[ { "uniprot_canonical_ac": "A0A8V0YAW3-1", "uniprot_ac": "A0A8V0YAW3", "uniprot_id": "A0A8V0YAW3_CHICK", "mass": { "chemical_mass": 14241.0, "monoisotopic_mass": 14241.0 }, "refseq": { "ac": "XP_025000955", "name": "potassium voltage-gated channel subfamily E member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000955" }, "gene_names": [ { "name": "KCNE1", "type": "recommended", "evidence": [ { "id": "A0A8V0YAW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ] }, { "name": "KCNE1", "type": "synonym", "evidence": [ { "id": "XP_025000955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000955" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily E member 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YAW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily E member 1", "type": "synonym", "evidence": [ { "id": "XP_025000955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025000955.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000955" } ] }, { "annotation": "Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE1 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit. Associates with KCNQ1/KVLQT1 alpha subunit to form the slowly activating delayed rectifier cardiac potassium (IKs) channel responsible for ventricular muscle action potential repolarization. The outward current reaches its steady state only after 50 seconds. Assembly with KCNH2/HERG alpha subunit Kv channel may regulate the rapidly activating component of the delayed rectifying potassium current (IKr) in heart.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3#function" }, { "database": "UniProtKB", "id": "ARBA00045479", "url": "https://www.uniprot.org/uniprotkb/ARBA00045479#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3", "locus": { "chromosome": "1", "start_pos": 105974571, "end_pos": 105991704, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012863", "url": "https://www.ensembl.org/id/ENSGALG00010012863" } ] } } ], "crossref": [ { "id": "101748386", "url": "https://www.ncbi.nlm.nih.gov/gene/101748386", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ESCRACY", "url": "https://omabrowser.org/oma/group/ESCRACY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAW3", "url": "https://www.orthodb.org/?gene=A0A8V0YAW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15282:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15282:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5576890", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576890", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025000955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVLSNDTALSILLSKLLQDHLEQTNSTAPSTVGSTGSSLEIIYVLMMVGLFGFFTVGVMVTNIRARRLEDSHNPYNTYIATDIWHKKDQEYFQAKLIENYKLCCVFENQLAVEQPSIHIPEEKSS", "length": 126, "header": "tr|A0A8V0YAW3-1|A0A8V0YAW3_CHICK Isoform 1 of Potassium voltage-gated channel subfamily E member 1 OS=Gallus gallus OX=9031 GN=KCNE1 PE=3 SV=1 CANONICAL=A0A8V0YAW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3/entry", "sequence": { "sequence": "MLVLSNDTALSILLSKLLQDHLEQTNSTAPSTVGSTGSSLEIIYVLMMVGLFGFFTVGVMVTNIRARRLEDSHNPYNTYIATDIWHKKDQEYFQAKLIENYKLCCVFENQLAVEQPSIHIPEEKSS", "length": 126, "header": "tr|A0A8V0YAW3-1|A0A8V0YAW3_CHICK Isoform 1 of Potassium voltage-gated channel subfamily E member 1 OS=Gallus gallus OX=9031 GN=KCNE1 PE=3 SV=1 CANONICAL=A0A8V0YAW3-1" }, "locus": { "chromosome": "1", "start_pos": 105977235, "end_pos": 105976858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030850.1", "url": "https://www.ensembl.org/id/ENSGALT00010030850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017901.1", "url": "https://www.ensembl.org/id/ENSGALP00010017901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5576890", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576890", "resource": "Reactome", "description": "Phase 3 - rapid repolarisation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I2H9-1", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "Kcne1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILSNSTTVMPFLATLWRETAQQGGDASGLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQKKDKAFFQARVLESCRACYVIENQVAVEQPATHLPELKPLS", "length": 129 }, "evidence": [ { "id": "A0A8V0YAW3", "url": "https://omabrowser.org/oma/group/A0A8V0YAW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1TV48-1", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "KCNE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MILSNATAVTPFLTKLWQGTVQQGSNTSGLARRSPGHDDGKLAALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPYNVYIQSDSWQEKDKAYFQARVLENCRACYVIENQLAVERPSVYLPEMKRLS", "length": 129 }, "evidence": [ { "id": "A0A8V0YAW3", "url": "https://omabrowser.org/oma/group/A0A8V0YAW3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15382-1", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "KCNE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP", "length": 129 }, "evidence": [ { "id": "A0A8V0YAW3", "url": "https://omabrowser.org/oma/group/A0A8V0YAW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15383-1", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "Kcne1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALSNSTTVLPFLASLWQETDEPGGNMSADLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKALFQARVLESFRACYVIENQAAVEQPATHLPELKPLS", "length": 130 }, "evidence": [ { "id": "A0A8V0YAW3", "url": "https://omabrowser.org/oma/group/A0A8V0YAW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23299-1", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "Kcne1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLPNSTTVLPFLARLWQETAEQGGNVSGLARKSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKAVFQARVLESFRACYVIENQAAVEQPATHLPELKPLS", "length": 129 }, "evidence": [ { "id": "A0A8V0YAW3", "url": "https://omabrowser.org/oma/group/A0A8V0YAW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "id": "GO:1902282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902282", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "telethonin binding", "id": "GO:0031433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031433", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "membrane repolarization during action potential", "id": "GO:0086011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "ventricular cardiac muscle cell action potential", "id": "GO:0086005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "secretory granule organization", "id": "GO:0033363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "vestibular nucleus development", "id": "GO:0021750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW3" } ], "pmid": "" }, { "name": "potassium ion export across plasma membrane", "id": "GO:0097623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097623", "evidence": [ { 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERAASSIQVLLQAAEFLERRERRDRIPPCLAEAEHGYASPCPARPRQAGGGGRSVHNALEKHRRAQLRRCLEQLKQQVPLGTGPARPTTLSLLHRARLHIQRLQEQEVRARRVKDRLRSRQQSLRQRLEQLLSPCGAERSRADSLDSSQLSEQSGSDGEEAEIDVEGAGLGAEPLVGFSTGKDHSYSSPRGPWS", "length": 195, "header": "tr|A0A8V0YAZ9-1|A0A8V0YAZ9_CHICK Isoform 1 of Max dimerization protein 3 OS=Gallus gallus OX=9031 GN=MXD3 PE=4 SV=1 CANONICAL=A0A8V0YAZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9/entry", "sequence": { "sequence": "MERAASSIQVLLQAAEFLERRERRDRIPPCLAEAEHGYASPCPARPRQAGGGGRSVHNALEKHRRAQLRRCLEQLKQQVPLGTGPARPTTLSLLHRARLHIQRLQEQEVRARRVKDRLRSRQQSLRQRLEQLLSPCGAERSRADSLDSSQLSEQSGSDGEEAEIDVEGAGLGAEPLVGFSTGKDHSYSSPRGPWS", "length": 195, "header": "tr|A0A8V0YAZ9-1|A0A8V0YAZ9_CHICK Isoform 1 of Max dimerization protein 3 OS=Gallus gallus OX=9031 GN=MXD3 PE=4 SV=1 CANONICAL=A0A8V0YAZ9-1" }, "locus": { "chromosome": "13", "start_pos": 9812379, "end_pos": 9811482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022684.1", "url": "https://www.ensembl.org/id/ENSGALT00010022684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013100.1", "url": "https://www.ensembl.org/id/ENSGALP00010013100.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ9" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 104, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YB15-1", "uniprot_ac": "A0A8V0YB15", "uniprot_id": "A0A8V0YB15_CHICK", "mass": { "chemical_mass": 103498.0, "monoisotopic_mass": 103498.0 }, "refseq": { "ac": "XP_040559313", "name": "PMS1 protein homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559313" }, "gene_names": [ { "name": "PMS1", "type": "recommended", "evidence": [ { "id": "A0A8V0YB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ] }, { "name": "PMS1", "type": "synonym", "evidence": [ { "id": "XP_040559313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559313" } ] } ], "protein_names": [ { "name": "PMS1 homolog 1, mismatch repair system component", "type": "synonym", "evidence": [ { "id": "A0A8V0YB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15/entry#names_and_taxonomy" } ] }, { "name": "PMS1 protein homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040559313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040559313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PMS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15", "locus": { "chromosome": "7", "start_pos": 345800, "end_pos": 387382, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012885", "url": "https://www.ensembl.org/id/ENSGALG00010012885" } ] } } ], "crossref": [ { "id": "A0A8V0YB15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB15", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03485", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03485", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16926", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16926", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21985", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21985", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423980", "url": "https://www.ncbi.nlm.nih.gov/gene/423980", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB15", "url": "https://www.orthodb.org/?gene=A0A8V0YB15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGC3", "url": "https://www.orthodb.org/?gene=A0A8V0YGC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHE4", "url": "https://www.orthodb.org/?gene=A0A8V0YHE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJE2", "url": "https://www.orthodb.org/?gene=A0A8V0YJE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10073:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10073:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01119", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01119", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040559313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQLSAETIRLLSSSQVITSVVSVVKELIENSLDASATTIDIRLENYGFDKIEVRDNGNGIKVADVPVMAIKHYTSKISSSEDLERLTTYGFRGEALGSICCISEVLVTTRTADDDISTQYVLDSSGHVTSQKPSHLGQGTTVTVLKLFKNLPVRKQFYSTNRKCKEELKKVHDLLIAYGIIKPELRITFVHNKAVIWQKNRVSDHKMACMSVLGTAVMGSMVPFQHCCEDPEINLSGFLPKAESDSSLTSLSSSERSFIFVNSRPVHQKEILKLIRQYYSVLMQKDSTRLYPVFFLNITVPASAVDVNVTPDKTEVLLQYKESVLLAVENVLKSLYGPLPATVSGEANKTDVTSEDMFVHKAGQTDVVVNEKEPSGNNDLHAHTSFLSFNSDVQSYQAGKNTEICLNHQIFSGDTVHSCLEEKEASKNDAFQEGSLQLLCEEEQKGQNTTGIPSNSAPVDPGSKEEGGCLLSSDNAEEALVPEDLPEISADNWSMGNAFKNSSGDNLEPVKVLIPDAGGAINKQSERSDEQSHDPQIPDPSIRKTNVIDEKTGHITAYDLISGRIIRKSKSAFEHFIQEYRSKFVSENPRCSMKDILLKIEEQWKNLNEEEKQEYELKAARDLERYNREANKAMQQAARRPVKENERQKPRLKASLPKQQKLDKMLCAQIDKKPKSNQPVKVVTVPFSLSACRPQFQRHEKSDSDKHELCLIRRQSFPDIWIFATEKKLMLLNPYRLEEALLRKRLLMNHKLPVEKLEKPVVLSDSLLGESHYMDVLHKMQKDYQGLNGLSYLSDPRLVANGFQIKVIEGASATESHMEIEGMANCLSYYGISDLKEILNAVVNRNAKEVYECRPLKVINYLEGEAVRLARQLPLHLSKEDVENTIYRMKQQLGKENKGCVHGRPFFHHLTDIPEVNKP", "length": 920, "header": "tr|A0A8V0YB15-1|A0A8V0YB15_CHICK Isoform 1 of PMS1 homolog 1, mismatch repair system component OS=Gallus gallus OX=9031 GN=PMS1 PE=3 SV=1 CANONICAL=A0A8V0YB15-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15/entry", "sequence": { "sequence": "MKQLSAETIRLLSSSQVITSVVSVVKELIENSLDASATTIDIRLENYGFDKIEVRDNGNGIKVADVPVMAIKHYTSKISSSEDLERLTTYGFRGEALGSICCISEVLVTTRTADDDISTQYVLDSSGHVTSQKPSHLGQGTTVTVLKLFKNLPVRKQFYSTNRKCKEELKKVHDLLIAYGIIKPELRITFVHNKAVIWQKNRVSDHKMACMSVLGTAVMGSMVPFQHCCEDPEINLSGFLPKAESDSSLTSLSSSERSFIFVNSRPVHQKEILKLIRQYYSVLMQKDSTRLYPVFFLNITVPASAVDVNVTPDKTEVLLQYKESVLLAVENVLKSLYGPLPATVSGEANKTDVTSEDMFVHKAGQTDVVVNEKEPSGNNDLHAHTSFLSFNSDVQSYQAGKNTEICLNHQIFSGDTVHSCLEEKEASKNDAFQEGSLQLLCEEEQKGQNTTGIPSNSAPVDPGSKEEGGCLLSSDNAEEALVPEDLPEISADNWSMGNAFKNSSGDNLEPVKVLIPDAGGAINKQSERSDEQSHDPQIPDPSIRKTNVIDEKTGHITAYDLISGRIIRKSKSAFEHFIQEYRSKFVSENPRCSMKDILLKIEEQWKNLNEEEKQEYELKAARDLERYNREANKAMQQAARRPVKENERQKPRLKASLPKQQKLDKMLCAQIDKKPKSNQPVKVVTVPFSLSACRPQFQRHEKSDSDKHELCLIRRQSFPDIWIFATEKKLMLLNPYRLEEALLRKRLLMNHKLPVEKLEKPVVLSDSLLGESHYMDVLHKMQKDYQGLNGLSYLSDPRLVANGFQIKVIEGASATESHMEIEGMANCLSYYGISDLKEILNAVVNRNAKEVYECRPLKVINYLEGEAVRLARQLPLHLSKEDVENTIYRMKQQLGKENKGCVHGRPFFHHLTDIPEVNKP", "length": 920, "header": "tr|A0A8V0YB15-1|A0A8V0YB15_CHICK Isoform 1 of PMS1 homolog 1, mismatch repair system component OS=Gallus gallus OX=9031 GN=PMS1 PE=3 SV=1 CANONICAL=A0A8V0YB15-1" }, "locus": { "chromosome": "7", "start_pos": 384578, "end_pos": 346457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030926.1", "url": "https://www.ensembl.org/id/ENSGALT00010030926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017961.1", "url": "https://www.ensembl.org/id/ENSGALP00010017961.1" } ] } }, { "isoform_ac": "A0A8V0YGC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC3/entry", "sequence": { "sequence": "MRSLTKQLLHLVACKENYGFDKIEVRDNGNGIKVADVPVMAIKHYTSKISSSEDLERLTTYGFRGEALGSICCISEVLVTTRTADDDISTQYVLDSSGHVTSQKPSHLGQGTTVTVLKLFKNLPVRKQFYSTNRKCKEELKKVHDLLIAYGIIKPELRITFVHNKAVIWQKNRVSDHKMACMSVLGTAVMGSMVPFQHCCEDPEINLSGFLPKAESDSSLTSLSSSERSFIFVNSRPVHQKEILKLIRQYYSVLMQKDSTRLYPVFFLNITVPASAVDVNVTPDKTEVLLQYKESVLLAVENVLKSLYGPLPATVSGEANKTDVTSEDMFVHKAGQTDVVVNEKEPSGNNDLHAHTSFLSFNSDVQSYQAGKNTEICLNHQIFSGDTVHSCLEEKEASKNDAFQEGSLQLLCEEEQKGQNTTGIPSNSAPVDPGSKEEGGCLLSSDNAEEALVPEDLPEISADNWSMGNAFKNSSGDNLEPVKVLIPDAGGAINKQSERSDEQSHDPQIPDPSIRKTNVIDEKTGHITAYDLISGRIIRKSKSAFEHFIQEYRSKFVSENPRCSMKDILLKIEEQWKNLNEEEKQEYELKAARDLERYNREANKAMQQAARRPVKENERQKPRLKASLPKQQKLDKMLCAQIDKKPKSNQPVKVVTVPFSLSACRPQFQRHEKSDSDKHELCLIRRQSFPDIWIFATEKKLMLLNPYRLEEALLRKRLLMNHKLPVEKLEKPVVLSDSLLGESHYMDVLHKMQKDYQGLNGLSYLSDPRLVANGFQIKVIEGASATESHMEIEGMANCLSYYGISDLKEILNAVVNRNAKEVYECRPLKVINYLEGEAVRLARQLPLHLSKEDVENTIYRMKQQLGKENKGCVHGRPFFHHLTDIPEVNKP", "length": 891, "header": "tr|A0A8V0YGC3-1|A0A8V0YGC3_CHICK Computationally mapped isoform of PMS1 homolog 1, mismatch repair system component OS=Gallus gallus OX=9031 GN=PMS1 PE=3 SV=1 CANONICAL=A0A8V0YB15-1" }, "locus": { "chromosome": "7", "start_pos": 383478, "end_pos": 346457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030916.1", "url": "https://www.ensembl.org/id/ENSGALT00010030916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017955.1", "url": "https://www.ensembl.org/id/ENSGALP00010017955.1" } ] } }, { "isoform_ac": "A0A8V0YHE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE4/entry", "sequence": { "sequence": "MKQLSAETIRLLSSSQVITSVVSVVKELIENSLDASATTIDIRLENYGFDKIEVRDNGNGIKVADVPVMAIKHYTSKISSSEDLERLTTYGFRGEALGSICCISEVLVTTRTADDDISTQYVLDSSGHVTSQKPSHLGQGTTVTVLKLFKNLPVRKQFYSTNRKCKEELKKVHDLLIAYGIIKPELRITFVHNKINLSGFLPKAESDSSLTSLSSSERSFIFVNSRPVHQKEILKLIRQYYSVLMQKDSTRLYPVFFLNITVPASAVDVNVTPDKTEVLLQYKESVLLAVENVLKSLYGPLPATVSGEANKTDVTSEDMFVHKAGQTDVVVNEKEPSGNNDLHAHTSFLSFNSDVQSYQAGKNTEICLNHQIFSGDTVHSCLEEKEASKNDAFQEGSLQLLCEEEQKGQNTTGIPSNSAPVDPGSKEEGGCLLSSDNAEEALVPEDLPEISADNWSMGNAFKNSSGDNLEPVKVLIPDAGGAINKQSERSDEQSHDPQIPDPSIRKTNVIDEKTGHITAYDLISGRIIRKSKSAFEHFIQEYRSKFVSENPRCSMKDILLKIEEQWKNLNEEEKQEYELKAARDLERYNREANKAMQQAARRPVKENERQKPRLKASLPKQQKLDKMLCAQIDKKPKSNQPVKVVTVPFSLSACRPQFQRHEKSDSDKHELCLIRRQSFPDIWIFATEKKLMLLNPYRLEEALLRKRLLMNHKLPVEKLEKPVVLSDSLLGESHYMDVLHKMQKDYQGLNGLSYLSDPRLVANGFQIKVIEGASATESHMEIEGMANCLSYYGISDLKEILNAVVNRNAKEVYECRPLKVINYLEGEAVRLARQLPLHLSKEDVENTIYRMKQQLGKENKGCVHGRPFFHHLTDIPEVNKP", "length": 881, "header": "tr|A0A8V0YHE4-1|A0A8V0YHE4_CHICK Computationally mapped isoform of PMS1 homolog 1, mismatch repair system component OS=Gallus gallus OX=9031 GN=PMS1 PE=3 SV=1 CANONICAL=A0A8V0YB15-1" }, "locus": { "chromosome": "7", "start_pos": 384578, "end_pos": 346457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030920.1", "url": "https://www.ensembl.org/id/ENSGALT00010030920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017958.1", "url": "https://www.ensembl.org/id/ENSGALP00010017958.1" } ] } }, { "isoform_ac": "A0A8V0YJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE2/entry", "sequence": { "sequence": "MVTVSSRGQERCQRVLVTTRTADDDISTQYVLDSSGHVTSQKPSHLGQGTTVTVLKLFKNLPVRKQFYSTNRKCKEELKKVHDLLIAYGIIKPELRITFVHNKAVIWQKNRVSDHKMACMSVLGTAVMGSMVPFQHCCEDPEINLSGFLPKAESDSSLTSLSSSERSFIFVNSRPVHQKEILKLIRQYYSVLMQKDSTRLYPVFFLNITVPASAVDVNVTPDKTEVLLQYKESVLLAVENVLKSLYGPLPATVSGEANKTDVTSEDMFVHKAGQTDVVVNEKEPSGNNDLHAHTSFLSFNSDVQSYQAGKNTEICLNHQIFSGDTVHSCLEEKEASKNDAFQEGSLQLLCEEEQKGQNTTGIPSNSAPVDPGSKEEGGCLLSSDNAEEALVPEDLPEISADNWSMGNAFKNSSGDNLEPVKVLIPDAGGAINKQSERSDEQSHDPQIPDPSIRKTNVIDEKTGHITAYDLISGRIIRKSKSAFEHFIQEYRSKFVSENPRCSMKDILLKIEEQWKNLNEEEKQEYELKAARDLERYNREANKAMQQAARRPVKENERQKPRLKASLPKQQKLDKMLCAQIDKKPKSNQPVKVVTVPFSLSACRPQFQRHEKSDSDKHELCLIRRQSFPDIWIFATEKKLMLLNPYRLEEALLRKRLLMNHKLPVEKLEKPVVLSDSLLGESHYMDVLHKMQKDYQGLNGLSYLSDPRLVANGFQIKVIEGASATESHMEIEGMANCLSYYGISDLKEILNAVVNRNAKEVYECRPLKVINYLEGEAVRLARQLPLHLSKEDVENTIYRMKQQLGKENKGCVHGRPFFHHLTDIPEVNKP", "length": 829, "header": "tr|A0A8V0YJE2-1|A0A8V0YJE2_CHICK Computationally mapped isoform of PMS1 homolog 1, mismatch repair system component OS=Gallus gallus OX=9031 GN=PMS1 PE=3 SV=1 CANONICAL=A0A8V0YB15-1" }, "locus": { "chromosome": "7", "start_pos": 380770, "end_pos": 346457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030915.1", "url": "https://www.ensembl.org/id/ENSGALT00010030915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017954.1", "url": "https://www.ensembl.org/id/ENSGALP00010017954.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" }, { "name": "mismatched DNA binding", "id": "GO:0030983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" }, { "name": "mismatch repair complex", "id": "GO:0032300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB15" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 567, "end_pos": 635, "start_aa": "Ile", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 502, "end_pos": 504 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YB18-1", "uniprot_ac": "A0A8V0YB18", "uniprot_id": "A0A8V0YB18_CHICK", "mass": { "chemical_mass": 90286.0, "monoisotopic_mass": 90286.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100859022", "type": "recommended", "evidence": [ { "id": "A0A8V0YB18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ] } ], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YB18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859022", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18", "locus": {} } ], "crossref": [ { "id": "A0A8V0YB18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB18", "url": "https://www.orthodb.org/?gene=A0A8V0YB18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAAREGSCGRRQRALLCCVLVAAWEAARGQLRYSVPEELPKGSFVGDVAKDLALELATLGARGARVVSQGRRQYFALHASSGHLVTAERIDREQLCENEPQCVLRCELIVEGEMKVYAISVEIMDINDNAPSFKKVEAEEQINEMTSPGARFPLPEAHDPDVGVNSLQSYALSGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLTVTASDPDDGTNGDVLYTFPEISDKASNIFHLEPDSGAIRLLKNLDFEEAEFHELKVRARDGGALSDTAKVSISVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQVLYPPAAPAPGAGVGAWGSASGAWSWAGVELAPRSAEPGALVAKVVAVDADAGQNAWLSYELAKATEPGLFRVGLHSGEVRTARSPLARDAARHSLVVVVKDRGRPALSATATLTVVLAESVAELLSELGSAAAPAEPAGSLTRWLVLAVAAVSCLFLAFLLLLLALRLRRWRRSRLPPPPSAGAALRGVPASHFVGIDGVRAFLRSYSHDVSLTADSRKSQLRCAGGSCCDTLPARPPPDEAAPLRGEDAAAHRAAEPDGLPVSAATVHYTSTSGFFISVCFQP", "length": 847, "header": "tr|A0A8V0YB18-1|A0A8V0YB18_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100859022 PE=4 SV=1 CANONICAL=A0A8V0YB18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18/entry", "sequence": { "sequence": "MCAAREGSCGRRQRALLCCVLVAAWEAARGQLRYSVPEELPKGSFVGDVAKDLALELATLGARGARVVSQGRRQYFALHASSGHLVTAERIDREQLCENEPQCVLRCELIVEGEMKVYAISVEIMDINDNAPSFKKVEAEEQINEMTSPGARFPLPEAHDPDVGVNSLQSYALSGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLTVTASDPDDGTNGDVLYTFPEISDKASNIFHLEPDSGAIRLLKNLDFEEAEFHELKVRARDGGALSDTAKVSISVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQVLYPPAAPAPGAGVGAWGSASGAWSWAGVELAPRSAEPGALVAKVVAVDADAGQNAWLSYELAKATEPGLFRVGLHSGEVRTARSPLARDAARHSLVVVVKDRGRPALSATATLTVVLAESVAELLSELGSAAAPAEPAGSLTRWLVLAVAAVSCLFLAFLLLLLALRLRRWRRSRLPPPPSAGAALRGVPASHFVGIDGVRAFLRSYSHDVSLTADSRKSQLRCAGGSCCDTLPARPPPDEAAPLRGEDAAAHRAAEPDGLPVSAATVHYTSTSGFFISVCFQP", "length": 847, "header": "tr|A0A8V0YB18-1|A0A8V0YB18_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100859022 PE=4 SV=1 CANONICAL=A0A8V0YB18-1" }, "locus": { "chromosome": "13", "start_pos": 1455803, "end_pos": 1452457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027386.1", "url": "https://www.ensembl.org/id/ENSGALT00010027386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015640.1", "url": "https://www.ensembl.org/id/ENSGALP00010015640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YB18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB18" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 134, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YB32-1", "uniprot_ac": "A0A8V0YB32", "uniprot_id": "A0A8V0YB32_CHICK", "mass": { "chemical_mass": 40147.0, "monoisotopic_mass": 40147.0 }, "refseq": {}, "gene_names": [ { "name": "CRHBP", "type": "recommended", "evidence": [ { "id": "A0A8V0YB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ] } ], "protein_names": [ { "name": "Corticotropin-releasing factor-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32/entry#names_and_taxonomy" } ] }, { "name": "Corticotropin-releasing hormone-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YB32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32#function" }, { "database": "UniProtKB", "id": "ARBA00024997", "url": "https://www.uniprot.org/uniprotkb/ARBA00024997#function" }, { "database": "UniProtKB", "id": "A0A8V0YI07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI07#function" }, { "database": "UniProtKB", "id": "PIRNR009279", "url": "https://www.uniprot.org/uniprotkb/PIRNR009279#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRHBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32", "locus": { "chromosome": "Z", "start_pos": 23908404, "end_pos": 23917620, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011451", "url": "https://www.ensembl.org/id/ENSGALG00010011451" } ] } } ], "crossref": [ { "id": "A0A8V0YB32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB32", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB32", "url": "https://www.orthodb.org/?gene=A0A8V0YB32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI07", "url": "https://www.orthodb.org/?gene=A0A8V0YI07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10278:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10278:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373080", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373080", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRLLPAGSEQQVLSAHGGAATMPSAFQLQCHLVLILLAASKGDTRYLEVRDAGEDEPFLLLSEDLKRELSAGHIYRRSLPAGTGCVLPAGRAEPSPVSAGCIDMLSIEGQFTFTADQPQLHCATFFIGEPEELLTIEYDFVNIDCQGGDFLKVFDGWILKGEKFPSSLDHPLPTSQRYTDFCESGAVQRSIRSSQNVAMIFFRIHQPGNGFTITVKKSANLFPCNVISQTPSGRFTMVIPHQHRNCSFSIIYPVVIKISDLILGHLNGLFLKNPSVGCAGVGDFVELLGGTGLDPSKMFPLADLCHSFHGSAQMKIGCDNTVLRMVSSGKHINRVTFEYYQLDLQEIENRKENSIEEFCFPGI", "length": 365, "header": "tr|A0A8V0YB32-1|A0A8V0YB32_CHICK Isoform 1 of Corticotropin-releasing factor-binding protein OS=Gallus gallus OX=9031 GN=CRHBP PE=3 SV=1 CANONICAL=A0A8V0YB32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32/entry", "sequence": { "sequence": "MPRRLLPAGSEQQVLSAHGGAATMPSAFQLQCHLVLILLAASKGDTRYLEVRDAGEDEPFLLLSEDLKRELSAGHIYRRSLPAGTGCVLPAGRAEPSPVSAGCIDMLSIEGQFTFTADQPQLHCATFFIGEPEELLTIEYDFVNIDCQGGDFLKVFDGWILKGEKFPSSLDHPLPTSQRYTDFCESGAVQRSIRSSQNVAMIFFRIHQPGNGFTITVKKSANLFPCNVISQTPSGRFTMVIPHQHRNCSFSIIYPVVIKISDLILGHLNGLFLKNPSVGCAGVGDFVELLGGTGLDPSKMFPLADLCHSFHGSAQMKIGCDNTVLRMVSSGKHINRVTFEYYQLDLQEIENRKENSIEEFCFPGI", "length": 365, "header": "tr|A0A8V0YB32-1|A0A8V0YB32_CHICK Isoform 1 of Corticotropin-releasing factor-binding protein OS=Gallus gallus OX=9031 GN=CRHBP PE=3 SV=1 CANONICAL=A0A8V0YB32-1" }, "locus": { "chromosome": "Z", "start_pos": 23916826, "end_pos": 23908972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027397.1", "url": "https://www.ensembl.org/id/ENSGALT00010027397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015651.1", "url": "https://www.ensembl.org/id/ENSGALP00010015651.1" } ] } }, { "isoform_ac": "A0A8V0YI07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI07/entry", "sequence": { "sequence": "MVTVHKAWMDRLRSELQCHLVLILLAASKGDTRYLEVRDAGEDEPFLLLSEDLKRELSAGHIYRRSLRCIDMLSIEGQFTFTADQPQLHCATFFIGEPEELLTIEYDFVNIDCQGGDFLKVFDGWILKGEKFPSSLDHPLPTSQRYTDFCESGAVQRSIRSSQNVAMIFFRIHQPGNGFTITVKKSANLFPCNVISQTPSGRFTMVIPHQHRNCSFSIIYPVVIKISDLILGHLNGLFLKNPSVGCAGVGDFVELLGGTGLDPSKMFPLADLCHSFHGSAQMKIGCDNTVLRMVSSGKHINRVTFEYYQLDLQEIENRKENSIEEFCFPGI", "length": 331, "header": "tr|A0A8V0YI07-1|A0A8V0YI07_CHICK Computationally mapped isoform of Corticotropin-releasing factor-binding protein OS=Gallus gallus OX=9031 GN=CRHBP PE=3 SV=1 CANONICAL=A0A8V0YB32-1" }, "locus": { "chromosome": "Z", "start_pos": 23917490, "end_pos": 23908972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027401.1", "url": "https://www.ensembl.org/id/ENSGALT00010027401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015655.1", "url": "https://www.ensembl.org/id/ENSGALP00010015655.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-373080", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373080", "resource": "Reactome", "description": "Class B/2 (Secretin family receptors)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "maternal aggressive behavior", "id": "GO:0002125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "synaptic transmission, dopaminergic", "id": "GO:0001963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "behavioral response to ethanol", "id": "GO:0048149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "negative regulation of corticotropin secretion", "id": "GO:0051460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051460", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB32" } ], "pmid": "" }, { "name": "cellular response to gonadotropin-releasing hormone", "id": "GO:0097211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB32", "url": 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This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147938.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147938" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CES1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34", "locus": {} } ], "crossref": [ { "id": "A0A8V0YB34", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB34", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415786", "url": "https://www.ncbi.nlm.nih.gov/gene/415786", 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"categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEKNTLLSLILTAGITALVATGQKAEQPEVVTKYGTARGYQFKVDAAERSVNVFLGLPFAKAPVGPLRFSEPQPPEPWKGVRDATSYPPMCLQDKVLGQFLSDVFTNRKEKVRLQMSEDCLYLNIYTPVSTEKQEKLPVFVWIHGGGLVLGAASSYDGSALAAFDNVVVVTIQYRLGIVGYFSTGDKYARGNWGYLDQVAALQWIQENIIHFGGDPGSVTICGESAGGISVSALVLSPLAKGLFHKAISESGTAIRALFTDKPEEEAQRIAAASGCEKSSSAALVECLREKTEEEMEQITLKMDMTTLKLCYTSPGKCEQPSMFISSTVDGVFFPKSPRELLSEKAINAVPYIIGVNNCEFGWVIPEMMKVPDFTEGLDKEVARQVLQSSFVLSFKSVPSDIVDLVFNEYIGKAESRAQVRDGLLDAIGDHMFVFPAIEVAGYHRDAGHPVYFYEFQHRPSSATGVVPEFVKADHGDEIAFVFGKPFLAGNATEEENKLSRAVMKYWTNFARNGNPNGEGLVHWPQYDLDERYLEIDLIQKAAKKLKEDKMEFWVQLTEQMRSERRRERTDL", "length": 574, "header": "tr|A0A8V0YB34-1|A0A8V0YB34_CHICK Isoform 1 of Carboxylic ester hydrolase OS=Gallus gallus OX=9031 GN=CES1L1 PE=1 SV=1 CANONICAL=A0A8V0YB34-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34/entry", "sequence": { "sequence": "MATEKNTLLSLILTAGITALVATGQKAEQPEVVTKYGTARGYQFKVDAAERSVNVFLGLPFAKAPVGPLRFSEPQPPEPWKGVRDATSYPPMCLQDKVLGQFLSDVFTNRKEKVRLQMSEDCLYLNIYTPVSTEKQEKLPVFVWIHGGGLVLGAASSYDGSALAAFDNVVVVTIQYRLGIVGYFSTGDKYARGNWGYLDQVAALQWIQENIIHFGGDPGSVTICGESAGGISVSALVLSPLAKGLFHKAISESGTAIRALFTDKPEEEAQRIAAASGCEKSSSAALVECLREKTEEEMEQITLKMDMTTLKLCYTSPGKCEQPSMFISSTVDGVFFPKSPRELLSEKAINAVPYIIGVNNCEFGWVIPEMMKVPDFTEGLDKEVARQVLQSSFVLSFKSVPSDIVDLVFNEYIGKAESRAQVRDGLLDAIGDHMFVFPAIEVAGYHRDAGHPVYFYEFQHRPSSATGVVPEFVKADHGDEIAFVFGKPFLAGNATEEENKLSRAVMKYWTNFARNGNPNGEGLVHWPQYDLDERYLEIDLIQKAAKKLKEDKMEFWVQLTEQMRSERRRERTDL", "length": 574, "header": "tr|A0A8V0YB34-1|A0A8V0YB34_CHICK Isoform 1 of Carboxylic ester hydrolase OS=Gallus gallus OX=9031 GN=CES1L1 PE=1 SV=1 CANONICAL=A0A8V0YB34-1" }, "locus": { "chromosome": "11", "start_pos": 10823588, "end_pos": 10815860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022735.1", "url": "https://www.ensembl.org/id/ENSGALT00010022735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013140.1", "url": "https://www.ensembl.org/id/ENSGALP00010013140.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415786", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415786", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" }, { "id": "R-GGA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" }, { "id": "R-GGA-5578768", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578768", "resource": "Reactome", "description": "Physiological factors" }, { "id": "R-GGA-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z298-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLYALILLSLSAMAWGGYPSSPPVVNTTHGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMYEFQSRPSFSSELKPKTVTGDHGDEVYSVFGAPILREGSSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYNQKKGYLQIGATTQQAQGLKDKEVSLWTELRAKKPPQTGHTEL", "length": 562 }, "evidence": [ { "id": "A0A8V0YB34", "url": "https://omabrowser.org/oma/group/A0A8V0YB34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-5693702" ], "output_participant_list": [ "R-ALL-5693711", "R-ALL-5693712" ], "enzyme_list": [ "A0A8V0YB34-1" ], "evidence": [ { "id": "R-GGA-5693691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693691" } ] }, { "id": "R-GGA-9619024", "name": "CES1 trimer hydrolyses ACEI pro-drugs to ACEIs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [ "R-ALL-140972" ], "enzyme_list": [ "A0A8V0YB34-1" ], "evidence": [ { "id": "R-GGA-9619024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9619024" } ] }, { "id": "R-GGA-9727567", "name": "CES1 hydrolyses sacubitril to sacubitrilat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046791799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARSRRPWLSVVLGLVLGFTAASWLIAPRVAEMNEKKRRGASLCSYYSRAAGPGAAGGAAAAGEQPAAAAVLGGTGVRSSPWELPAAEDGTVSSPAAGGEAEQEEEEEGGEKRSGRPGGSRNGSGDWGGAAGCAKPRNFLYVGVMTAQKYLGSRAVAAQRTWAPSVPGRVEFFSSQGSAAPPGLPPLPVVALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGEKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRMGYIQDLHNSKIHTAITLHPNKRPAYQYRLHNYILSRKISELRYRTILLHRECALMSKLSNSKVTKEDQQLGVIPSFNHFQPRERSEVIEWEFLTGKFLYSMVESQPPRQSVSSVLRAALDDTVMQVMEMINENSRSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKVTVPVRRHAFLQQLFSKPFFREAEELDVRSLLEDTNTDTQSFSFPSNSFKIFSSSFQGTKDIVGHSDKKIHILVPLIGRFDIFSRFMENFEKTCLIPRQNVKLAIILFSSELGQDSIKHIDLMKEYSIKYPKADMTLVPMTGKFSRGLGLEMASSQFDNGTLLLFCDVDLIFTPDFLQRCRENTIQGEQVYYPIIFSQYDPKVVYGGNPPADSSFIFTKRTGFWREYGFGITCIYKSDLLTAGGFDTSIQGWGLEDVDLYTKVITSGLKAFRSQEVGVVHIFHPVRCDPSLDPKQYKMCLGSKASTFASTMQLAELWLEKRLGVRYNQTVS", "length": 850, "header": "tr|A0A8V0YBC7-1|A0A8V0YBC7_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=CHSY3 PE=3 SV=1 CANONICAL=A0A8V0YBC7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7/entry", "sequence": { "sequence": "MAARSRRPWLSVVLGLVLGFTAASWLIAPRVAEMNEKKRRGASLCSYYSRAAGPGAAGGAAAAGEQPAAAAVLGGTGVRSSPWELPAAEDGTVSSPAAGGEAEQEEEEEGGEKRSGRPGGSRNGSGDWGGAAGCAKPRNFLYVGVMTAQKYLGSRAVAAQRTWAPSVPGRVEFFSSQGSAAPPGLPPLPVVALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGEKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRMGYIQDLHNSKIHTAITLHPNKRPAYQYRLHNYILSRKISELRYRTILLHRECALMSKLSNSKVTKEDQQLGVIPSFNHFQPRERSEVIEWEFLTGKFLYSMVESQPPRQSVSSVLRAALDDTVMQVMEMINENSRSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKVTVPVRRHAFLQQLFSKPFFREAEELDVRSLLEDTNTDTQSFSFPSNSFKIFSSSFQGTKDIVGHSDKKIHILVPLIGRFDIFSRFMENFEKTCLIPRQNVKLAIILFSSELGQDSIKHIDLMKEYSIKYPKADMTLVPMTGKFSRGLGLEMASSQFDNGTLLLFCDVDLIFTPDFLQRCRENTIQGEQVYYPIIFSQYDPKVVYGGNPPADSSFIFTKRTGFWREYGFGITCIYKSDLLTAGGFDTSIQGWGLEDVDLYTKVITSGLKAFRSQEVGVVHIFHPVRCDPSLDPKQYKMCLGSKASTFASTMQLAELWLEKRLGVRYNQTVS", "length": 850, "header": "tr|A0A8V0YBC7-1|A0A8V0YBC7_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=CHSY3 PE=3 SV=1 CANONICAL=A0A8V0YBC7-1" }, "locus": { "chromosome": "Z", "start_pos": 45956526, "end_pos": 45809202, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022907.1", "url": "https://www.ensembl.org/id/ENSGALT00010022907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013241.1", "url": "https://www.ensembl.org/id/ENSGALP00010013241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415598", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415598", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N783-1", "protein_name": "Hexosyltransferase", "gene_name": "CHSY3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPGAQQPLPEPHARQWPGQSPPPARQELRGPQLPEAAPGVTSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPVAEGEPEEEDGGAAGHRRSGQPGSSHNGSGDGGAAASSSRPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGVGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDIYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSHEVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGVMPSFNHFQPRERDEVIEWEFLTGKLLYSASENQPPRQSINSILRTALDDTVLQVMEMINENAKTRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSDTQSFSFISNSLKILSSFQGAKEVGGHSEKKIHILVPLIGRYDTFLRFMENFENTCLIPKQNVKLVIILFSKDSGQDSNKHIELIQEYQNKYPKAEITLIPMKGEFSRGLGLEMGSSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGSPPTDDDFVFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTVQLAELWLEKHLGVRYNRTLS", "length": 882 }, "evidence": [ { "id": "A0A8V0YBC7", "url": "https://omabrowser.org/oma/group/A0A8V0YBC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R6S5-1", "protein_name": "Hexosyltransferase", "gene_name": "Chsy3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSQPRLQQSPPPASHQLPGPLRPEVAPGGPSLRSSPWQQPAPLPQRRRGHKPEGATALPGAPAAKGEPEEEDGGAAGPRKGGRPRSSQNGSGDGGAAAPTSGPGDFLYVGVMTAQKYLGSRALAAHRTWARFIPGRVEFFSSQQPPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGMMPSFNHFQPQERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREMEELDINSLVESINSGTPATGFSFISNSLKILSSLQEPKEIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCIIPKQNVKLVIILFSRDSGQESIKHIELIQEYQNRYPSAEMTLIPMKGEFSRGLGLEMGSSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTRMGNSPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVIQSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMKLAELWLEKHLGVRDNRTLS", "length": 886 }, "evidence": [ { "id": "A0A8V0YBC7", "url": "https://omabrowser.org/oma/group/A0A8V0YBC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DTK1-1", "protein_name": "Chondroitin sulfate synthase 3", "gene_name": "Chsy3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSRPRLEQSPPPASHELPGPQQPEAAPGGPSFRSSPWQQPALLPQRRRGHTPEGATALPGAPAAKGEPEEEDGGAADPRKGGRPGSSHNGSGDGGAAVPTSGPGDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQSPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGRTPSFNHFQPRERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREVEELDVNRLVESINSGTQSFSVISNSLKILSSLQEAKDIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCLIPKQNVKLVIILFSRDAGQESIKHIELIQEYQSRYPSAEMMLIPMKGEFSRGLGLEMASSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTHMRNPPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRDNRTLS", "length": 884 }, "evidence": [ { "id": "A0A8V0YBC7", "url": "https://omabrowser.org/oma/group/A0A8V0YBC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q70JA7-1", "protein_name": "Chondroitin sulfate synthase 3", "gene_name": "CHSY3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAENQPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNSLKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFSRDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVDLIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS", "length": 882 }, "evidence": [ { "id": "A0A8V0YBC7", "url": "https://omabrowser.org/oma/group/A0A8V0YBC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KUZ9-1", "protein_name": "Hexosyltransferase", "gene_name": "Chsy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLQHTMTKRKTLIIGFFGIALGLCIGTMLKNYLALEIVKRCSLRPTNLKTPADIIGLRDEDTIQNSQRNLVFVGVMTAKSFLEGRARAVYDTWGKEVPGRMAFFSSEGSYSDDLPVVGLKNVDDRYPPQKKSFMMLYYMYEHYIDRFEWFIRADDDVYMEPDKLERFLRSIDSSKPQFIGQAGKGNSEEFGLLSLEFDENFCMGGPGVILSSETLRRVAPHIPSCLKNLYSTHEDVEVGRCVQKFAGIPCTWNYEMQYILRHNSSGRNAYTGKLKRKEIHNAITLHPIKQAPLMYRLHSYVQGLKAEEMRQESLLLHRDIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNILGISPELNKFVPASTDDLLDWSFIARSLYSASSANPKQKIDSAMREGLEDAITEVMENINNYSRQRGRVIEFRELLYGYHRLDALHGQDMILDLLLIYKKYRGKKMTVPVRRHLYVQRAFTGIFVKEVDEDFYNVTLQQSLLGSLFQNGMARLSSHFTMPSGLLSPTQDKIVFVLPIAGRLGTFERFLRTYERVCVRGEQHCDLLVVIFGSPDELGDHLQLLHDLHARHVYQQVNWIQRSSAFSRGVALDVAARSSYIRQEDIILFIDVDMVFEVETLQRVRMHTQRGKQVYLPIVFSQYDPQRRSGDAGGSEDEGETPRIDDERGYFRQFGFGICAIYKSDILDEDINGFDKDITGWGLEDVKFLEKIVRVGTRQRGFLANTAELAMDYNEAAEQWRRLSVFRAPDPTLVHIYHDISCDVQLDAPQYNMCLGTKANSLGSTRLMEQLFHSSPENVQFAADFNRQKQQQQQQQQAR", "length": 832 }, "evidence": [ { "id": "A0A8V0YBC7", "url": "https://omabrowser.org/oma/group/A0A8V0YBC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ], "pmid": "" }, { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1971487", "name": "Chondroitin polymerase complex transfers GalNAc to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RW56-1", "A0A8V0Z8G8-1", "A0A8V0YBC7-1", "A0A8V0ZC44-1" ], "evidence": [ { "id": "R-GGA-1971487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971487" } ] }, { "id": "R-GGA-1971491", "name": "Chondroitin polymerase complex transfers GlcA to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RW56-1", "A0A8V0Z8G8-1", "A0A8V0YBC7-1", "A0A8V0ZC44-1" ], "evidence": [ { "id": "R-GGA-1971491", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971491" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1L1RW56", "gene_name": "CHPF2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A1L1RW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RW56" } ] } ] }, { "uniprot_ac": "A0A8V0YBC7", "gene_name": "CHSY3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G8", "gene_name": "CHSY1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0Z8G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G8" } ] } ] }, { "uniprot_ac": "A0A8V0ZC44", "gene_name": "CHPF", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZC44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 846, "end_pos": 848 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YDL7-1", "uniprot_ac": "A0A8V0YDL7", "uniprot_id": "A0A8V0YDL7_CHICK", "mass": { "chemical_mass": 52009.0, "monoisotopic_mass": 52009.0 }, "refseq": { "ac": "NP_001264350", "name": "carboxypeptidase Q precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" }, "gene_names": [ { "name": "CPQ", "type": "recommended", "evidence": [ { "id": "A0A8V0YDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7" } ] }, { "name": "CPQ", "type": "synonym", "evidence": [ { "id": "NP_001264350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ] }, { "name": "PGCP", "type": "synonym", "evidence": [ { "id": "NP_001264350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ] } ], "protein_names": [ { "name": "Carboxypeptidase Q", "type": "recommended", "evidence": [ { "id": "A0A8V0YDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7/entry#names_and_taxonomy" } ] }, { "name": "Plasma glutamate carboxypeptidase", "type": "synonym", "evidence": [ { "id": "A0A8V0YDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7/entry#names_and_taxonomy" } ] }, { "name": "carboxypeptidase Q precursor", "type": "synonym", "evidence": [ { "id": "NP_001264350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ] }, { "name": "plasma glutamate carboxypeptidase", "type": "synonym", "evidence": [ { "id": "NP_001264350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01002787.1, BX934029.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_001264350.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ] }, { "annotation": "Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD5#function" }, { "database": "UniProtKB", "id": "ARBA00025534", "url": "https://www.uniprot.org/uniprotkb/ARBA00025534#function" }, { "database": "UniProtKB", "id": "A0A8V0YDL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7#function" } ] }, { "annotation": "Identification and validation of quantitative trait loci for ascites syndrome in broiler chickens using whole genome resequencing. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001264350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" }, { "database": "PubMed", "id": "32434464", "url": "https://glygen.org/publication/PubMed/32434464" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPQ", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7", "locus": { "chromosome": "2", "start_pos": 126738152, "end_pos": 126574447, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011497", "url": "https://www.ensembl.org/id/ENSGALG00010011497" } ] } } ], "crossref": [ { "id": "A0A8V0YDL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03883", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03883", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420238", "url": "https://www.ncbi.nlm.nih.gov/gene/420238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420238", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVFYNRP", "url": "https://omabrowser.org/oma/group/IVFYNRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBD5", "url": "https://www.orthodb.org/?gene=A0A8V0YBD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDL7", "url": "https://www.orthodb.org/?gene=A0A8V0YDL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12053", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12053", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12053:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12053:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYLFLIFFMNLLPRYAGRSLSRDGNYPKAFEGIRNEIAGYYDVAKAIIDLAVYGKAQNRSYERLAVFADTIGPRLSGSANLDAAIKYMYNALQKDGLENVHLEPVKVPHWERGEEFAMMLEPRNHSIAILGLGSSVATPPEGITAEVIVVSSFDELHRRAQEAKGKIVVYNQPFISYGETVRYRSLGAVEAAKVGAVASLIRSVASFSIDSPHTGWQNYQSGVPQIPTACISVEDAEMMSRMSFRGTKIIVYLKMGAKTYPDSTSFNTVAEIVGSKYPEQIVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTGEEQGGIGAEQYYQLHKENISNFDIVMESDEGTFKPSGLAFTGNAKARDIIKEIMALLLPINITEVYDTADGTDINFWMRDGVPGASLRDDLSKYFWFHHSQGDTMTVQDPNQMNLCAAVWTVVSYIIADMEEMLPR", "length": 469, "header": "tr|A0A8V0YDL7-1|A0A8V0YDL7_CHICK Isoform 1 of Carboxypeptidase Q OS=Gallus gallus OX=9031 GN=CPQ PE=1 SV=1 CANONICAL=A0A8V0YDL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD5/entry", "sequence": { "sequence": "MTEVRRIVTFSWSLLNLVNIELFEEYSPRPSVEKRERMKYLFLIFFMNLLPRYAGRSLSRDGNYPKAFEGIRNEIAGYYDVAKAIIDLAVYGKAQNRSYERLAVFADTIGPRLSGSANLDAAIKYMYNALQKDGLENVHLEPVKVPHWERGEEFAMMLEPRNHSIAILGLGSSVATPPEGITAEVIVVSSFDELHRRAQEAKGKIVVYNQPFISYGETVRYRSLGAVEAAKVGAVASLIRSVASFSIDSPHTGWQNYQSGVPQIPTACISVEDAEMMSRMSFRGTKIIVYLKMGAKTYPDSTSFNTVAEIVGSKYPEQIVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTGEEQGGIGAEQYYQLHKENISNFDIVMESDEGTFKPSGLAFTGNAKARDIIKEIMALLLPINITEVYDTADGTDINFWMRDGVPGASLRDDLSKYFWFHHSQGDTMTVQDPNQMNLCAAVWTVVSYIIADMEEMLPR", "length": 506, "header": "tr|A0A8V0YBD5-1|A0A8V0YDL7_CHICK Computationally mapped isoform of Carboxypeptidase Q OS=Gallus gallus OX=9031 GN=CPQ PE=1 SV=1 CANONICAL=A0A8V0YDL7-1" }, "locus": { "chromosome": "2", "start_pos": 126737818, "end_pos": 126575922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027531.1", "url": "https://www.ensembl.org/id/ENSGALT00010027531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015768.1", "url": "https://www.ensembl.org/id/ENSGALP00010015768.1" } ] } }, { "isoform_ac": "A0A8V0YDL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL7/entry", "sequence": { "sequence": "MKYLFLIFFMNLLPRYAGRSLSRDGNYPKAFEGIRNEIAGYYDVAKAIIDLAVYGKAQNRSYERLAVFADTIGPRLSGSANLDAAIKYMYNALQKDGLENVHLEPVKVPHWERGEEFAMMLEPRNHSIAILGLGSSVATPPEGITAEVIVVSSFDELHRRAQEAKGKIVVYNQPFISYGETVRYRSLGAVEAAKVGAVASLIRSVASFSIDSPHTGWQNYQSGVPQIPTACISVEDAEMMSRMSFRGTKIIVYLKMGAKTYPDSTSFNTVAEIVGSKYPEQIVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTGEEQGGIGAEQYYQLHKENISNFDIVMESDEGTFKPSGLAFTGNAKARDIIKEIMALLLPINITEVYDTADGTDINFWMRDGVPGASLRDDLSKYFWFHHSQGDTMTVQDPNQMNLCAAVWTVVSYIIADMEEMLPR", "length": 469, "header": "tr|A0A8V0YDL7-1|A0A8V0YDL7_CHICK Isoform 1 of Carboxypeptidase Q OS=Gallus gallus OX=9031 GN=CPQ PE=1 SV=1 CANONICAL=A0A8V0YDL7-1" }, "locus": { "chromosome": "2", "start_pos": 126737818, "end_pos": 126594619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027532.1", "url": "https://www.ensembl.org/id/ENSGALT00010027532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015769.1", "url": "https://www.ensembl.org/id/ENSGALP00010015769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification and validation of quantitative trait loci for ascites syndrome in broiler chickens using whole genome resequencing.", "journal": "BMC genetics", "date": "2020-05-20", "authors": "Parveen Alia, Jackson Christa D, Dey Shatovisha, Tarrant Katy, Anthony Nicholas, Rhoads Douglas D", "evidence": [ { "database": "RefSeq", "id": "NP_001264350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264350" } ], "reference": [ { "type": "PubMed", "id": "32434464", "url": "https://glygen.org/publication/PubMed/32434464" } ] } ], "pathway": [ { "id": "gga:420238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HK39-1", "protein_name": "Carboxypeptidase Q", "gene_name": "Cpq", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKVLFFMLVSAVHLLSQGSGKPIYKSDFSQRTFQEIKREIASYEDVAKAIIDLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQHDGLENVHLEPVKIPHWERGEESAVMLLPRIHKMSILGLGSSVATPPGGITAEVLVVTSFDELQRRASEARGKIIVYNQPYISYGMTVQYRVHGAVEAAKVGAVASLIRSVASFSIYSPHTGFQAYQDGVPKIPTACITVEDAEMMSRMASRGNKIVVHLEMGAKTYPDADSYNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGIGASQYYEQHKANISNYSLVMESDSGIILPTGLQFTGSDKARAIMKEVMSLLQPLNVTNLFSDGEGTDIDFWIQAGVPGASLRDDDLYKYFSFHHTNGDTMTVMDPKQMNVAAAVWAVVAYVVADMEEMLPRS", "length": 473 }, "evidence": [ { "id": "A0A8V0YDL7", "url": "https://omabrowser.org/oma/group/A0A8V0YDL7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q17QK3-1", "protein_name": "Carboxypeptidase Q", "gene_name": "CPQ", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFLLFMFVGVVHLLPLASGKAIYGNGPSQRTFQEIKEEIAHYGDVAKSIINLTVYGKAQNRSYERLALLVDTVGPRLSGSKNLERAIEIMQQNLKGDGLENVHLEPVKIPHWERGEESAVMLEPRIHKMAILGLGSSIGTPPEGITAEVLVVTSFDELQRRGPDAEGKIVVYNQPYTNYSAAVQYRMEGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQKGVPKIPTACITVEDAEMMSRMASRGNRIVVQLKMGAKSYPDADSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGSSQYYQLHKANSSNYSLVMESDLGTFLPSGLKFTGSDKARVIMEEVMSLLQPINITQVLKAGDGTDINFWIQDGVPGASLLDDLYKYFSFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADLEEMLPRS", "length": 472 }, "evidence": [ { "id": "A0A8V0YDL7", "url": "https://omabrowser.org/oma/group/A0A8V0YDL7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54MN6-1", "protein_name": "Carboxypeptidase Q", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASQYTKLQSIEVEDNLLLPYQVSNPTQKKSQNKFASYFYRVKGYIIKKWKILLLLMFVLLLIAGVILIPVLVLRYKTSTISDQCDEYGKEIINNAVQKGTEAYSRLSTLVTLFPGRLSGSEQLENAIDWIQDMMLDDGFDLVKTDDVEVTHWVRGDESATILQPYHRKMNMLGLGGSIAGNVTAEVIVVSSFDELDTLQDQVKGKIVLFNAIFTNYSSTVQYRSGGASAAAKYGGVAALVRSITPYSLGTPHTGVMFYQDGIDKIPTAAITLEDADLIQNLAILNQTVIVNLYMEAQTMPTNAISRNVMAQINGSTYPDEVVVIGGHTDSWDVAQGAMDDGGGIVVAWEALRLIKSLGIIPKRTIRVVGWTNEENGAAGGAAYAQLYTNETFFSIESDIGVTQPLGFNVMASEQTITDLQLIADKVLSPIKTTSIVEGEVGTDNGFLVSNGKPGAQLITDESKYFWYHHTAGDAMDKMDPSQMNQCVAAMATMALCISNWVGQLN", "length": 506 }, "evidence": [ { "id": "A0A8V0YDL7", "url": "https://omabrowser.org/oma/group/A0A8V0YDL7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6IRK9-1", "protein_name": "Carboxypeptidase Q", "gene_name": "Cpq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLFFLFVAVVHLFSLGSGKAIYKSGVSQRTFQEIKEEIANYEDVAKAIINLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLENVHLEQVRIPHWERGEESAVMVVPRIHKLAILGLGGSIGTPPEGITAEVLVVASFVELQRRASEARGKIVVYNQPYTDYGKTVQYRERGAVEAAKVGAVASLIRSVASFSIYSPHTGHQGYQDGVPKIPTACITIEDAEMMSRMASRGDKIVIHLKMGAKTYPDTDSFNTVAEITGSKYPEEVVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGVGASQYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDKARAIMKEVMSLLQPLNITKVFNDAEGTDINFWIQAGVPGASLRDDLYKYFFFHHSHGDTMTAMDPKQMNVAAAVWAVVAYVVADMEEMLPRS", "length": 472 }, "evidence": [ { "id": "A0A8V0YDL7", "url": "https://omabrowser.org/oma/group/A0A8V0YDL7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WVJ3-1", "protein_name": "Carboxypeptidase Q", "gene_name": "Cpq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSLFFLFIVHLLALGSGKAVFKNGVSQRTFREIKEEIANYEDVAKAIINLAVYGKYQNRSYERLGLLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLENVHLEQVRIPHWERGEESAVMLEPRIHKMAILGLGSSIGTPPGGITAEVLVVASFDELQRRASEARGKIIVYNQPYTGYEKTVQYRVQGAVEAAKVGAVASLIQSVASFSIYSPHTGIQKYQDGVPKIPTACITVEDAEMMSRMASRGNKIVIHLEMGAKTYPDTDSFNTVAEITGSMYPEEVVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLRLVLWTAEEQGGIGASQYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDKARAIMKEVMNLLQPLNVTKVFSNGEGTDINFWIQAGVPGASLRDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVAYVVADMDEMLPRS", "length": 470 }, "evidence": [ { "id": "A0A8V0YDL7", "url": "https://omabrowser.org/oma/group/A0A8V0YDL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y646-1", "protein_name": "Carboxypeptidase Q", "gene_name": "CPQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YBE7-1", "uniprot_ac": "A0A8V0YBE7", "uniprot_id": "A0A8V0YBE7_CHICK", "mass": { "chemical_mass": 84273.0, "monoisotopic_mass": 84273.0 }, "refseq": {}, "gene_names": [ { "name": "UIMC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YBE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE7" } ] } ], "protein_names": [ { "name": "BRCA1-A complex subunit RAP80", "type": "recommended", "evidence": [ { "id": "A0A8V0YBE7", "database": "UniProtKB", "url": 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"MPRRRKATEGPDSRGQDGEEEEEEKRAAANAKKKRSFVDAFIVISDSDGEQESKEDSGLQTKRTKQQLDRTKFAAKRKIAQMTEEEQFALALKMSEQEARQVNCQEEEEEELLRKAIAESLNSCQPLDSSSATPQLSVEVLDTQSQSHPAEQEGCGILGGLAPCPDTLCSEDSSHSQSTRADGSGQMDVARSPLVVLRRLSQEIVESSLVSSIIVSPGKSQPLTRSSEKSSSPPKSDSSNMLPSTLREDLISLSPTFGRVPSGSWRLTPRRLFTSPSGSSKAADHKPKEQPLPCSGHPAGEASAGNSAQLFKSWTTEQGGSPRMSGAGAGTKHTLQSRRAATVCVTTEQAEQNEVSDSSPELCMLNVAEEKHEEEARDTVHYYWGIPFCPKGVDPNQYTNVILCQLEVYQKSLKQAQRQLLHKKEFGNPIVPSSSLSQNELRKGEQISRENGVADDTEDGDPGTPKECESITWLLPSKKREAESPGHNVEEEKNSTSDDEPTTSYCQASHVLSTEDVRGDGEPMQTAQSVCTLTPLGSKRSPDIARENCAEEEISVCPETQPSPSESIEPEREELSSVSKEAPMQAGGDGSADRTLSEGNHMPADHVPCPLCDRGFPAAEIELHAMYCNGIVGEDAATDSPVLTRGRRESRSKAAGGESSQTSSDSDKLWQGTRGDSSACWSSQRASLQVGSCFLCLPAGSGLQNIPSPLPLSLSLSLSLSPLSLWGWVALRPGMLLEPGLWELRVCSTSLQDTWQHSECSQGSPNAWLWEVAVLPHG", "length": 778, "header": "tr|A0A8V0YBE7-1|A0A8V0YBE7_CHICK Isoform 1 of BRCA1-A complex subunit RAP80 OS=Gallus gallus OX=9031 GN=UIMC1 PE=3 SV=1 CANONICAL=A0A8V0YBE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBE7-1", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "netrin receptor activity", "id": "GO:0005042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "anterior/posterior axon guidance", "id": "GO:0033564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 994, "end_pos": 996, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 363, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG7" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 619, "end_pos": 762, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 994, "end_pos": 996 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YBI4-1", "uniprot_ac": "A0A8V0YBI4", "uniprot_id": "A0A8V0YBI4_CHICK", "mass": { "chemical_mass": 43034.0, "monoisotopic_mass": 43034.0 }, "refseq": { "ac": "XP_046794267", "name": "KRR1 small subunit processome component homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267" }, "gene_names": [ { "name": "KRR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YBI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ] }, { "name": "HRB2", "type": "synonym", "evidence": [ { "id": "XP_046794267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267" } ] }, { "name": "KRR1", "type": "synonym", "evidence": [ { "id": "XP_046794267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267" } ] } ], "protein_names": [ { "name": "KRR1 small subunit processome component", "type": "recommended", "evidence": [ { "id": "A0A8V0YBI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4/entry#names_and_taxonomy" } ] }, { "name": "KRR-R motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YBI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4/entry#names_and_taxonomy" } ] }, { "name": "KRR1 small subunit processome component homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046794267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046794267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267" } ] }, { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4#function" }, { "database": "UniProtKB", "id": "ARBA00035000", "url": "https://www.uniprot.org/uniprotkb/ARBA00035000#function" } ] }, { "annotation": "Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4#function" }, { "database": "UniProtKB", "id": "PIRNR006515", "url": "https://www.uniprot.org/uniprotkb/PIRNR006515#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KRR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4", "locus": { "chromosome": "1", "start_pos": 37903805, "end_pos": 37910031, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012975", "url": "https://www.ensembl.org/id/ENSGALG00010012975" } ] } } ], "crossref": [ { "id": "A0A8V0YBI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417863", "url": "https://www.ncbi.nlm.nih.gov/gene/417863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TPDIDKW", "url": "https://omabrowser.org/oma/group/TPDIDKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBI4", "url": "https://www.orthodb.org/?gene=A0A8V0YBI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12581:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12581:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21800", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21800", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046794267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEAVEGNVRRPGKKKAVKAVDESELLTVPDGWKEPAFTREDNPRGLLEESSFATLFPKYREAYLKECWPLVQKALSEHYVNATLDLIEGSMTVTTTKKTFDPYAIIRARDLIKLLARSVPFEQAVRILQDDVACDIIKIGSLVRNRESFVKRRGRLLGPKGSTLKALELLTNCYIMVQGNTVSALGPFSGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELSKDPELRTQNWERFLPKFKRKNLKKRKEPKKKNIKKEYTPFPPPQPESQIDKELASGEYFLKESQKKRKRVEEIKAKQADAVKKRQEERNKAFIPPKEKPVVKAKKASTEKKIDIEAIKEKVKNAKKKKLGALPMEEVKLKMAADEKKKKKK", "length": 375, "header": "tr|A0A8V0YBI4-1|A0A8V0YBI4_CHICK Isoform 1 of KRR1 small subunit processome component OS=Gallus gallus OX=9031 GN=KRR1 PE=1 SV=1 CANONICAL=A0A8V0YBI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4/entry", "sequence": { "sequence": "MAAPEAVEGNVRRPGKKKAVKAVDESELLTVPDGWKEPAFTREDNPRGLLEESSFATLFPKYREAYLKECWPLVQKALSEHYVNATLDLIEGSMTVTTTKKTFDPYAIIRARDLIKLLARSVPFEQAVRILQDDVACDIIKIGSLVRNRESFVKRRGRLLGPKGSTLKALELLTNCYIMVQGNTVSALGPFSGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELSKDPELRTQNWERFLPKFKRKNLKKRKEPKKKNIKKEYTPFPPPQPESQIDKELASGEYFLKESQKKRKRVEEIKAKQADAVKKRQEERNKAFIPPKEKPVVKAKKASTEKKIDIEAIKEKVKNAKKKKLGALPMEEVKLKMAADEKKKKKK", "length": 375, "header": "tr|A0A8V0YBI4-1|A0A8V0YBI4_CHICK Isoform 1 of KRR1 small subunit processome component OS=Gallus gallus OX=9031 GN=KRR1 PE=1 SV=1 CANONICAL=A0A8V0YBI4-1" }, "locus": { "chromosome": "1", "start_pos": 37910005, "end_pos": 37905081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031134.1", "url": "https://www.ensembl.org/id/ENSGALT00010031134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018128.1", "url": "https://www.ensembl.org/id/ENSGALP00010018128.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "P25586-1", "protein_name": "KRR1 small subunit processome component", "gene_name": "KRR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN", "length": 316 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13601-1", "protein_name": "KRR1 small subunit processome component homolog", "gene_name": "KRR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPSLERPEKGAGKSEFRNQKPKPENQDESELLTVPDGWKEPAFSKEDNPRGLLEESSFATLFPKYREAYLKECWPLVQKALNEHHVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK", "length": 381 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3B7L9-1", "protein_name": "KRR1 small subunit processome component homolog", "gene_name": "KRR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSKQNGPTTASGKSELRSPKPTSENRDESELLTVPDGWKEPAFSKEDNPRGLLEESSFATLFPKYREAYLKECWPLVQKALNEHHINATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLLARSVSFEQAIRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKASQKKRQKMEAIKAKQAEALSKRQEERNKAFIPPKEKPVHLKKPKEASTETKIDVAALKEKVKKAKNKKLGALTAEEVKLKMEADEKKKKKK", "length": 382 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54UU6-1", "protein_name": "KRR1 small subunit processome component homolog", "gene_name": "krr1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKKDKTEIKVEEENKEKKQYKKKKEREELEIPKGIDPWKPLELKRDDVGKRVLYDDSSFATLFPKYREKYLQEIWKLVENVLHEHGIECKLDLIEGSMTVTTTKKCWDPVAILKARDLIKLLSRSVPFEHAQKVLNDDYNCDIIKIGGFVRNKERFVKRRQRLVGPDGSTLKAIELLTKCYVLVQGNTVSSIGPWNGLVQVRKIVEDCLKNIHPIYNIKELMIKRELEKDETLKNENWERYLPQFKKTNQNKKKKVQKKKKDRDAAPFAPPQLPRKEDLAMESGEYFASEEKKRRKIQADREAKHAESDQKRKDERQKSQIAPAEKDRSTTTTTNTSNIQDTLSNIKNNLKNNKRKEAPTNNADDFVLKKNKK", "length": 374 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BGA5-1", "protein_name": "KRR1 small subunit processome component homolog", "gene_name": "Krr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSAEAPAKEAQKRDSQPQKQKRETQDEAELLTVPDGWKEPAFSKEDNPRGLLEESSFATLFPKYREAYLKECWPLVQKALNEHHVKATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYVMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKSVKKEYTPFPPPQPESQIDKELASGEYFLKASQKKRQKMEAIKAKQAEALTKRQEERNKAFIPPKEKPAVKPKEASTETKIDVAAIKEKVKKAKTKKLGALTAEEVKLKMEADEKKQKRKK", "length": 380 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FT93-1", "protein_name": "KRR1 small subunit processome component", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEVEEIAHEEQNIEKREKKKGKHEKPKPWDDDPNIDRWTIEKFDPAWNPTGMTETSTFSTLFPQYREKYLQECWPRVESALKEYGVACKLNLVEGSMTVSTTRKTRDPYIIVKARDLIKLLSRSVPAPQAIKILEDEVQCDIIKIGNLVRNKERFVKRRQRLVGPNSSTLKALEILTNCYILVQGSTVAAMGPFKGLKQLRRIVEDCVQNIMHPVYHIKTLMMKKELEKDPALANESWDRFLPTFRKKNVKQKKPKSKEKKPYTPFPPPQPPSKIDMQLESGEYFMSDKKKSEKKWQEKQEKQSEKSTENKRKRDASFLPPEEPMNNNSNANKSEDGKNDITELTNSLKSKTKELKKQKKTHERVNAEEYIAGPSSSADKSSKKSKKIRD", "length": 391 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VPU8-1", "protein_name": "KRR1 small subunit processome component homolog", "gene_name": "dbe", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSESEAEETKISTEPVDNAWSMKIPAFRQEDNPHGMVEESSFATLFPKYRERYLKEVWPLVEQCLAEHHLKAELDLMEGSMVVKTSRKTWDPYIIIKARDMIKLMARSVPFEQAKRVLQDDIGCDIIKIGNLVHKKEKFVKRRQRLIGPNGATLKSIELLTDCYVLVQGNTVSALGPYKGLQQVRDIVLETMNNVHPIYNIKALMIKRELMKDPRLANEDWSRFLPKFKNKNISKRKQPKVKKQKKEYTPFPPSQPESKVDKQLASGEYFLNQEQKQAKRNQERTEKQKEAAKRQDERRNKDFVPPTEESAASSRKKEDGSSSSKVDVKALKAKLIKANKKARSS", "length": 345 }, "evidence": [ { "id": "A0A8V0YBI4", "url": "https://omabrowser.org/oma/group/A0A8V0YBI4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI4" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 206, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YE05-1", "uniprot_ac": "A0A8V0YE05", "uniprot_id": "A0A8V0YE05_CHICK", "mass": { "chemical_mass": 134626.0, "monoisotopic_mass": 134626.0 }, "refseq": { "ac": "NP_001039292", "name": "protocadherin-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" }, "gene_names": [ { "name": "PCDH1", "type": "recommended", "evidence": [ { "id": "A0A8V0YE05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ] }, { "name": "PCDH1", "type": "synonym", "evidence": [ { "id": "NP_001039292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] }, { "name": "protocadherin-1", "type": "synonym", "evidence": [ { "id": "NP_001039292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] } ], "protein_names": [ { "name": "Protocadherin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YE05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05/entry#names_and_taxonomy" } ] }, { "name": "cadherin", "type": "synonym", "evidence": [ { "id": "NP_001039292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] }, { "name": "protocadherin 1 (cadherin-like 1)", "type": "synonym", "evidence": [ { "id": "NP_001039292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] }, { "name": "protocadherin-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001039292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On or before Dec 9, 2021 this sequence version replaced XP_015149085.2, NP_001039292.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001039292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ] }, { "annotation": "Pcdh1-mediated cell adhesion plays an important role as neural crest cells coalesce to form the dorsal root ganglia, where it serves to sort cells to the mitotically active perimeter", "evidence": [ { "database": "RefSeq", "id": "NP_001039292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" }, { "database": "PubMed", "id": "18718533", "url": "https://glygen.org/publication/PubMed/18718533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCDH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05", "locus": { "chromosome": "13", "start_pos": 1724825, "end_pos": 1677836, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011619", "url": "https://www.ensembl.org/id/ENSGALG00010011619" } ] } } ], "crossref": [ { "id": "A0A8V0YE05", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE05", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416194", "url": "https://www.ncbi.nlm.nih.gov/gene/416194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416194", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRGAIWT", "url": "https://omabrowser.org/oma/group/HRGAIWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBS3", "url": "https://www.orthodb.org/?gene=A0A8V0YBS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE05", "url": "https://www.orthodb.org/?gene=A0A8V0YE05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIP5", "url": "https://www.orthodb.org/?gene=A0A8V0YIP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTPLDQRSGSRHGAQRRPHPTPLKHRMRTLTSCLALWFLCQLPALACGTRVVYKVQEEQPPNTLIGSLASDYGFPDVGHLYKLEVGAPYLRVDGKTGDIYTTETSIDRESLRECQHLLPGEPCYLEFEVSITDLMQNNSPRLLEGQIEVLDINDNTPNFASPVLTLTIPENTNIGTLFSIPPAMDRDSGPNGVASYELLAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDREQWDSYDLTIKVQDGGNPPRASSALLRITIVDMNDNAPKFEKALYEAELSENSPVGHSVIQVKANDSDQGANAEIDYSFHQASDMVRRLLRLDRNTGLITVQGPIDREDVSILKFSVMAKDKGANPRSARTQVVVTIKDMNDNAPSIEIRGIGLVTHQDGMANISEDVPVETAVALVQVSDRDEGENAVVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYESVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFSQSFTEVAFPENNEPNDLVMEVSASDADSGSNAKLVYSLVTDPSSKDSFTIDPDSGEIRVKAVLDREQRERYEFLVVAADKGSPSLKGTASVAINVMDRNDNDPKFMLSGYNFSVMENMPPLSPVGMVTVIDADKGENARIQLSVEQDNGDFVIQNGTGTILSSISFDREQQSTYTFRLKAVDGGDPPRSAYVGVTINVLDENDNAPFITSPSNATYKHILPHTSPGQQVSKVKAEDIDTGVNAELTYSITGGNPFELFQISPQSGDITLEKEILRKHHGLHRLVVRVNDKGKPSRHGTALVHFYVNETLANRTLLDTLVGHSLDTPLDIDIAGDPEYERSKQRSNILFGVIAGIVAVTLVIVLVVLVRYCRQREAKSGYQAGKKETKDLYAPKQASKSGKSKNKVKKSKSPKPPKPTEDEEETGLQKSLKFNLMNDSVSDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPATNTFVGTGDNNSTGSEQYSDYSYRTNPQKYTNKQLPHRRVTFSAASQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECTEFGHSDTCWMPGQSSPSRRPKNALKLSTFVPYQDRGSQEQVGNGSPRLSEERSTKMANLRLLPTYSAFSNSSHETCKDSPMEEIPLTQTSDFQPATTPSSQTTKREIYL", "length": 1225, "header": "tr|A0A8V0YE05-1|A0A8V0YE05_CHICK Isoform 1 of Protocadherin 1 OS=Gallus gallus OX=9031 GN=PCDH1 PE=1 SV=1 CANONICAL=A0A8V0YE05-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS3/entry", "sequence": { "sequence": "MQTPLDQRSGSRHGAQRRPHPTPLKHRMRTLTSCLALWFLCQLPALACGTRVVYKVQEEQPPNTLIGSLASDYGFPDVGHLYKLEVGAPYLRVDGKTGDIYTTETSIDRESLRECQHLLPGEPCYLEFEVSITDLMQNNSPRLLEGQIEVLDINDNTPNFASPVLTLTIPENTNIGTLFSIPPAMDRDSGPNGVASYELLAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDREQWDSYDLTIKVQDGGNPPRASSALLRITIVDMNDNAPKFEKALYEAELSENSPVGHSVIQVKANDSDQGANAEIDYSFHQASDMVRRLLRLDRNTGLITVQGPIDREDVSILKFSVMAKDKGANPRSARTQVVVTIKDMNDNAPSIEIRGIGLVTHQDGMANISEDVPVETAVALVQVSDRDEGENAVVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYESVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFSQSFTEVAFPENNEPNDLVMEVSASDADSGSNAKLVYSLVTDPSSKDSFTIDPDSGEIRVKAVLDREQRERYEFLVVAADKGSPSLKGTASVAINVMDRNDNDPKFMLSGYNFSVMENMPPLSPVGMVTVIDADKGENARIQLSVEQDNGDFVIQNGTGTILSSISFDREQQSTYTFRLKAVDGGDPPRSAYVGVTINVLDENDNAPFITSPSNATYKHILPHTSPGQQVSKVKAEDIDTGVNAELTYSITGGNPFELFQISPQSGDITLEKEILRKHHGLHRLVVRVNDKGKPSRHGTALVHFYVNETLANRTLLDTLVGHSLDTPLDIDIAGDPEYERSKQRSNILFGVIAGIVAVTLVIVLVVLVRYCRQREAKSGYQAGKKETKDLYAPKQASKSGKSKNKVKKSKSPKPPKPTEDEEETGLQKSLKFNLMNDSVSDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPATNTFVGTGDNNSTGSEQYSDYSYRTNPQKYTNKQLPHRRVTFSAASQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENESPERSRL", "length": 1105, "header": "tr|A0A8V0YBS3-1|A0A8V0YE05_CHICK Computationally mapped isoform of Protocadherin 1 OS=Gallus gallus OX=9031 GN=PCDH1 PE=1 SV=1 CANONICAL=A0A8V0YE05-1" }, "locus": { "chromosome": "13", "start_pos": 1722113, "end_pos": 1677962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027769.1", "url": "https://www.ensembl.org/id/ENSGALT00010027769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015918.1", "url": "https://www.ensembl.org/id/ENSGALP00010015918.1" } ] } }, { "isoform_ac": "A0A8V0YE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05/entry", "sequence": { "sequence": "MQTPLDQRSGSRHGAQRRPHPTPLKHRMRTLTSCLALWFLCQLPALACGTRVVYKVQEEQPPNTLIGSLASDYGFPDVGHLYKLEVGAPYLRVDGKTGDIYTTETSIDRESLRECQHLLPGEPCYLEFEVSITDLMQNNSPRLLEGQIEVLDINDNTPNFASPVLTLTIPENTNIGTLFSIPPAMDRDSGPNGVASYELLAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDREQWDSYDLTIKVQDGGNPPRASSALLRITIVDMNDNAPKFEKALYEAELSENSPVGHSVIQVKANDSDQGANAEIDYSFHQASDMVRRLLRLDRNTGLITVQGPIDREDVSILKFSVMAKDKGANPRSARTQVVVTIKDMNDNAPSIEIRGIGLVTHQDGMANISEDVPVETAVALVQVSDRDEGENAVVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYESVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFSQSFTEVAFPENNEPNDLVMEVSASDADSGSNAKLVYSLVTDPSSKDSFTIDPDSGEIRVKAVLDREQRERYEFLVVAADKGSPSLKGTASVAINVMDRNDNDPKFMLSGYNFSVMENMPPLSPVGMVTVIDADKGENARIQLSVEQDNGDFVIQNGTGTILSSISFDREQQSTYTFRLKAVDGGDPPRSAYVGVTINVLDENDNAPFITSPSNATYKHILPHTSPGQQVSKVKAEDIDTGVNAELTYSITGGNPFELFQISPQSGDITLEKEILRKHHGLHRLVVRVNDKGKPSRHGTALVHFYVNETLANRTLLDTLVGHSLDTPLDIDIAGDPEYERSKQRSNILFGVIAGIVAVTLVIVLVVLVRYCRQREAKSGYQAGKKETKDLYAPKQASKSGKSKNKVKKSKSPKPPKPTEDEEETGLQKSLKFNLMNDSVSDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPATNTFVGTGDNNSTGSEQYSDYSYRTNPQKYTNKQLPHRRVTFSAASQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECTEFGHSDTCWMPGQSSPSRRPKNALKLSTFVPYQDRGSQEQVGNGSPRLSEERSTKMANLRLLPTYSAFSNSSHETCKDSPMEEIPLTQTSDFQPATTPSSQTTKREIYL", "length": 1225, "header": "tr|A0A8V0YE05-1|A0A8V0YE05_CHICK Isoform 1 of Protocadherin 1 OS=Gallus gallus OX=9031 GN=PCDH1 PE=1 SV=1 CANONICAL=A0A8V0YE05-1" }, "locus": { "chromosome": "13", "start_pos": 1723821, "end_pos": 1677962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027770.1", "url": "https://www.ensembl.org/id/ENSGALT00010027770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015919.1", "url": "https://www.ensembl.org/id/ENSGALP00010015919.1" } ] } }, { "isoform_ac": "A0A8V0YIP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP5/entry", "sequence": { "sequence": "MQTPLDQRSGSRHGAQRRPHPTPLKHRMRTLTSCLALWFLCQLPALACGTRVVYKVQEEQPPNTLIGSLASDYGFPDVGHLYKLEVGAPYLRVDGKTGDIYTTETSIDRESLRECQHLLPGEPCYLEFEVSITDLMQNNSPRLLEGQIEVLDINDNTPNFASPVLTLTIPENTNIGTLFSIPPAMDRDSGPNGVASYELLAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDREQWDSYDLTIKVQDGGNPPRASSALLRITIVDMNDNAPKFEKALYEAELSENSPVGHSVIQVKANDSDQGANAEIDYSFHQASDMVRRLLRLDRNTGLITVQGPIDREDVSILKFSVMAKDKGANPRSARTQVVVTIKDMNDNAPSIEIRGIGLVTHQDGMANISEDVPVETAVALVQVSDRDEGENAVVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYESVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFSQSFTEVAFPENNEPNDLVMEVSASDADSGSNAKLVYSLVTDPSSKDSFTIDPDSGEIRVKAVLDREQRERYEFLVVAADKGSPSLKGTASVAINVMDRNDNDPKFMLSGYNFSVMENMPPLSPVGMVTVIDADKGENARIQLSVEQDNGDFVIQNGTGTILSSISFDREQQSTYTFRLKAVDGGDPPRSAYVGVTINVLDENDNAPFITSPSNATYKHILPHTSPGQQVSKVKAEDIDTGVNAELTYSITGGNPFELFQISPQSGDITLEKEILRKHHGLHRLVVRVNDKGKPSRHGTALVHFYVNETLANRTLLDTLVGHSLDTPLDIDIAGDPEYERSKQRSNILFGVIAGIVAVTLVIVLVVLVRYCRQREAKSGYQAGKKETKDLYAPKQASKSGKSKNKVKKSKSPKPPKPTEDEEETGLQKSLKFNLMNDSVSDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPATNTFVGTGDNNSTGSEQYSDYSYRTNPQKYTNKQLPHRRVTFSAASQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENDS", "length": 1099, "header": "tr|A0A8V0YIP5-1|A0A8V0YIP5_CHICK Computationally mapped isoform of Protocadherin 1 OS=Gallus gallus OX=9031 GN=PCDH1 PE=1 SV=1 CANONICAL=A0A8V0YE05-1" }, "locus": { "chromosome": "13", "start_pos": 1714247, "end_pos": 1677962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027768.1", "url": "https://www.ensembl.org/id/ENSGALT00010027768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015917.1", "url": "https://www.ensembl.org/id/ENSGALP00010015917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken protocadherin-1 functions to localize neural crest cells to the dorsal root ganglia during PNS formation.", "journal": "Mechanisms of development", "date": "2008", "authors": "Bononi Judy, Cole Angela, Tewson Paul, Schumacher Andrew, Bradley Roger", "evidence": [ { "database": "RefSeq", "id": "NP_001039292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039292" } ], "reference": [ { "type": "PubMed", "id": "18718533", "url": "https://glygen.org/publication/PubMed/18718533" } ] } ], "pathway": [ { "id": "gga:416194", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416194", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XVV3-1", "protein_name": "Protocadherin 1", "gene_name": "Pcdh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRRKTVLLILEPARMGPLRPSPGPGGQRLLLPPLLLALLLLLAPSASHTTQVVYKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQISGSPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGANPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLRVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEVRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLVHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKAAKGSKSKGKKSKSPKPVKPVEDEDDTGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSRRTKSSALKLSTFVPYQDRGGQEPAGAGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHDSCKDSATLEEIPLTQTSDFPPTATPASAQTSAKREIYL", "length": 1231 }, "evidence": [ { "id": "A0A8V0YE05", "url": "https://omabrowser.org/oma/group/A0A8V0YE05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AI27-1", "protein_name": "Protocadherin-1 isoform X1", "gene_name": "pcdh1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCQSANAMWSRWSAMLVWILLLLCCSANVVNTILYQVTEEQPPNTLIGSLASDQGLPDTGHLYKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNLFEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVEGLVGHSLYTPLEMDIAGDPDYSRDPHSNILFAVLGGFSVVILIIVVAMIIRHLVLKENKSGYQAGKKETKDLYAPKPGPKSNKNKKAKKSKAPKPANPSEEDEGGTLQKGLKFNLMNENVNDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQAVQDLPATNTFVGTGDNNSTGSDQYSDYSYKANSSKYSTKQLPHRRVTFSTANQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGKCTRECTEYGHSDSCWMPGQPSPNRSKSAKSGPKLSTFVPYQEREGQERLMADSSSKPHGEERSGGGSNKVASIRFLPPYTSAYSTGGDSGKDCPREEIPLNQTADYVPATTPSSQGSKREIYL", "length": 1211 }, "evidence": [ { "id": "A0A8V0YE05", "url": "https://omabrowser.org/oma/group/A0A8V0YE05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08174-1", "protein_name": "Protocadherin-1", "gene_name": "PCDH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQVGQPFQLSTPQPLPHPYHGAIWTEVWE", "length": 1060 }, "evidence": [ { "id": "A0A8V0YE05", "url": "https://omabrowser.org/oma/group/A0A8V0YE05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1159, "end_pos": 1161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE05" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 160, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YBU4-1", "uniprot_ac": "A0A8V0YBU4", "uniprot_id": "A0A8V0YBU4_CHICK", "mass": { "chemical_mass": 35015.0, "monoisotopic_mass": 35015.0 }, "refseq": { "ac": "NP_001265013", "name": "pyridoxal kinase isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013" }, "gene_names": [ { "name": "PDXK", "type": "recommended", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "name": "PDXK", "type": "synonym", "evidence": [ { "id": "NP_001265013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013" } ] } ], "protein_names": [ { "name": "Pyridoxal kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.35", "type": "synonym", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4/entry#names_and_taxonomy" } ] }, { "name": "Pyridoxine kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4/entry#names_and_taxonomy" } ] }, { "name": "pyridoxal kinase isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001265013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013" } ] }, { "name": "pyridoxal kinase", "type": "synonym", "evidence": [ { "id": "NP_001265013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01052550.1, BX934150.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000020.1. On May 10, 2013 this sequence version replaced XP_416755.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013" } ] }, { "annotation": "Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively. PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4#function" }, { "database": "UniProtKB", "id": "ARBA00045787", "url": "https://www.uniprot.org/uniprotkb/ARBA00045787#function" }, { "database": "UniProtKB", "id": "A0A8V0YFC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC5#function" }, { "database": "UniProtKB", "id": "A0A8V0YK35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK35#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDXK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4", "locus": { "chromosome": "1", "start_pos": 110191346, "end_pos": 110146949, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011950", "url": "https://www.ensembl.org/id/ENSGALG00010011950" } ] } } ], "crossref": [ { "id": "A0A8V0YBU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418549", "url": "https://www.ncbi.nlm.nih.gov/gene/418549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418549", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTQYGQW", "url": "https://omabrowser.org/oma/group/HTQYGQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBU4", "url": "https://www.orthodb.org/?gene=A0A8V0YBU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFC5", "url": "https://www.orthodb.org/?gene=A0A8V0YFC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK35", "url": "https://www.orthodb.org/?gene=A0A8V0YK35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10534", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10534", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10534:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10534:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08543", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08543", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-964975", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964975", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10224", "url": "https://www.rhea-db.org/rhea/10224", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25104", "url": "https://www.rhea-db.org/rhea/25104", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25108", "url": "https://www.rhea-db.org/rhea/25108", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPERECRVLSIQSHVVRGYVGNKAATFPLQVLGFEVDTVNSVQFSNHTGYAHWKGQVLNSDELHELYEGLKLNKVNQYDYVLTGYTRDTSFLAMVVDIVQELKQQNSNLVYVCDPVMGDKWNGEGSMYVPKDLLPVYRDKVVPVADIITPNQFEAELLTGRKIYTEKDALEVMDMLHAMGPETVVITSSDLQAPLGNDYLIALGSYRKTNADGTKITQRIRMESPKVDAAFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMQHVLQRTIKSAKAQAGEGNKPNSANLELRMVQSKKDIENPEIIVKATVL", "length": 314, "header": "tr|A0A8V0YBU4-1|A0A8V0YBU4_CHICK Isoform 1 of Pyridoxal kinase OS=Gallus gallus OX=9031 GN=PDXK PE=1 SV=1 CANONICAL=A0A8V0YBU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4/entry", "sequence": { "sequence": "MEPERECRVLSIQSHVVRGYVGNKAATFPLQVLGFEVDTVNSVQFSNHTGYAHWKGQVLNSDELHELYEGLKLNKVNQYDYVLTGYTRDTSFLAMVVDIVQELKQQNSNLVYVCDPVMGDKWNGEGSMYVPKDLLPVYRDKVVPVADIITPNQFEAELLTGRKIYTEKDALEVMDMLHAMGPETVVITSSDLQAPLGNDYLIALGSYRKTNADGTKITQRIRMESPKVDAAFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMQHVLQRTIKSAKAQAGEGNKPNSANLELRMVQSKKDIENPEIIVKATVL", "length": 314, "header": "tr|A0A8V0YBU4-1|A0A8V0YBU4_CHICK Isoform 1 of Pyridoxal kinase OS=Gallus gallus OX=9031 GN=PDXK PE=1 SV=1 CANONICAL=A0A8V0YBU4-1" }, "locus": { "chromosome": "1", "start_pos": 110185181, "end_pos": 110147053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028603.1", "url": "https://www.ensembl.org/id/ENSGALT00010028603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016427.1", "url": "https://www.ensembl.org/id/ENSGALP00010016427.1" } ] } }, { "isoform_ac": "A0A8V0YFC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC5/entry", "sequence": { "sequence": "MEPERECRVLSIQSHVVRGYVGNKAATFPLQVLGFEVDTVNSVQFSNHTGYAHWKGQVLNSDELHELYEGLKLNKVNQYDYVLTGYTRDTSFLAMVVDIVQELKQQNSNLVYVCDPVMGDKWNGEGSMYVPKDLLPVYRDKVVPVADIITPNQFEAELLTGRKIYTEKDALEFARKRA", "length": 178, "header": "tr|A0A8V0YFC5-1|A0A8V0YFC5_CHICK Computationally mapped isoform of Pyridoxal kinase OS=Gallus gallus OX=9031 GN=PDXK PE=1 SV=1 CANONICAL=A0A8V0YBU4-1" }, "locus": { "chromosome": "1", "start_pos": 110180513, "end_pos": 110147053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028602.1", "url": "https://www.ensembl.org/id/ENSGALT00010028602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016426.1", "url": "https://www.ensembl.org/id/ENSGALP00010016426.1" } ] } }, { "isoform_ac": "A0A8V0YK35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK35/entry", "sequence": { "sequence": "MFLRSQFFNVFGTHRRITGVGRDLMRSSSPVYPTIGHTGYAHWKGQVLNSDELHELYEGLKLNKVNQYDYVLTGYTRDTSFLAMVVDIVQELKQQNSNLVYVCDPVMGDKWNGEGSMYVPKDLLPVYRDKVVPVADIITPNQFEAELLTGRKIYTEKDALEVMDMLHAMGPETVVITSSDLQAPLGNDYLIALGSYRKTNADGTKITQRIRMESPKVDAAFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMQHVLQRTIKSAKAQAGEGNKPNSANLELRMVQSKKDIENPEIIVKATVL", "length": 303, "header": "tr|A0A8V0YK35-1|A0A8V0YK35_CHICK Computationally mapped isoform of Pyridoxal kinase OS=Gallus gallus OX=9031 GN=PDXK PE=1 SV=1 CANONICAL=A0A8V0YBU4-1" }, "locus": { "chromosome": "1", "start_pos": 110185181, "end_pos": 110165907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028599.1", "url": "https://www.ensembl.org/id/ENSGALT00010028599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016424.1", "url": "https://www.ensembl.org/id/ENSGALP00010016424.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418549", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418549", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-964975", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964975", "resource": "Reactome", "description": "Vitamin B6 activation to pyridoxal phosphate" } ], "orthologs": [ { "uniprot_canonical_ac": "B8A4Q2-1", "protein_name": "Pyridoxal kinase", "gene_name": "pdxkb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MECRVLSIQSHVVRGYVGNKSASFPLQVMGFEVDSINSVQFSNHTGYAHWKGQVLTADELHVLYEGIKLNNVNHYDYVLTGYNRDTSFLEMVADIVQELKRANPNLVYVCDPVLGDHGSMYVPQNLHPVYKNKVVPVADIITPNQFEAELLTGKNISTEKDAVEVMDLLHKMGPDTVVITSSDLPPRLGDRFLVSLGSQRILMPDGTRTTQRIRIEVPKVDAVFVGTGDLFAAMLLAWTHHYPTDLKTACEKTFSVMHHVIQRTISYAHEMAGPGRRPSPSQLELRMVQSKADIEDPAIVMEATVL", "length": 306 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O00764-1", "protein_name": "Pyridoxal kinase", "gene_name": "PDXK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL", "length": 312 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35331-1", "protein_name": "Pyridoxal kinase", "gene_name": "Pdxk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGECRVLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGYAHWKGQVLTSQELHALYEGLKANNVNKYDYVLTGYTRDKSFLGMVVDIVQELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYREKVVPMADIITPNQFEAELLSGRKIHSQEEAFAVMDVLHRMGPDTVVITSSDLPSPKGSDYLMALGSQRMRKPDGSTVTQRIRMEMRKVDPVFVGTGDLFAAMLLAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSRKDIEDPEIVVQATVL", "length": 312 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39988-1", "protein_name": "Putative pyridoxal kinase BUD16", "gene_name": "BUD16", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPRLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETDLKELLSGLFDNFSQDYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDEGQLYVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQTIPVIIVTSCDCKMFDDKDFIYCVASMEGKTPIVYRVPFIDSYFTGVGDLFSALLLDRVYKILSNPTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYETINIHQTDYIYARL", "length": 312 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0II59-1", "protein_name": "Pyridoxal kinase", "gene_name": "PDXK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYSHWKGQVLNSDELQELYDGLKLNSVNQYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVMGDQRDGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHTQEEALEVMDMLHSMGPDTVVITSSDLLSPRGSDYLMALGSQRTRAPDGSMVTQRIRMEMHKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDIESPEIVVQATVL", "length": 312 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55EK9-1", "protein_name": "Pyridoxal kinase", "gene_name": "pykA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPKVLSIQSWVCHGYVGNKCAVFALQHLGIEVDPINSVHLSNNTAYPTWKGESLTPNKLGDLFQGLEDNHLTSNYTHVLTGYNNSVQTLHTVLKIVKKLKSENPNLIYVCDPVLGDNNELYVPEDLVEVYKNEVIPNADYIFPNQTEVEFLTGIKIKNDQDALKAIDQFHKMGVKNVVITSLFFDTNPNDIIVIGSTINDDDNNNKYNQFKIKVGPKFNDYYTGTGDLLSSLLLGWSIREPTDLSLVCEKAISILYNIINETHNSKKSIPSNKEKQYYELRLVQSRKFIENSEIRFKSEKL", "length": 302 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7KUC2-1", "protein_name": "Pyridoxal kinase", "gene_name": "Pdxk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGATNADIKRVLSIQSHVVHGYVGNKVATYPLQLLGFDVDPLNSVQFSNHTGYKTFKGPVSNEKELATIFEGLEENELLPLYSHLLTGYIGNPLFLRQVGHILKKLRQANPGLVYVCDPVMGDNGQLYVPKELLPVYRDEIIPLADIITPNQFEVELLTEKEVRSEAAVWEAMEWFHQRGIKTVVISSSDLGQPGVLRAFLSQQNGPRLAIDIPKQGGKDLVFTGTGDLFASLFLAHSHGSKDIANVFEKTIASLQAVIKRTVASLPNGGNGPVKAAERELKLVQSKTEIEQPQVLLKAQRLN", "length": 304 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K183-1", "protein_name": "Pyridoxal kinase", "gene_name": "Pdxk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGECRVLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGYAHWKGQVLKSQELHELYEGLKVNDVNKYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYRDKVVPVADIITPNQFEAELLSGRKIHSQEEAFEVMDMLHCMGPDTVVITSSDLPSSQGSDYLIALGSQRMRKPDGSTVTQRIRMEMRKVEAVFVGTGDLFAAMLLAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSKRDIEDPEIVVQATVL", "length": 312 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8W1X2-1", "protein_name": "Pyridoxal kinase", "gene_name": "PK", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTTPPVLSLALPSDTGRVLSIQSHTVQGYVGNKSAVFPLQLLGYDVDPINSVQFSNHTGYPTFKGQVLNGQQLCDLIEGLEANDLLFYTHVLTGYIGSVSFLDTILEVINKLRSVNPNLTYVCDPVMGDEGKLYVPEELVHVYREKVVPLASMLTPNQFEAEKLTGLRINSEEDGREACAILHAAGPSKVVITSITIGGILLLIGSHQKEKGLKPEQFKILIHKIPAYFTGTGDLMTALLLGWSNKYPDNLDKAAELAVSTLQALLRRTLDDYKRAGYDPTSSSLEIRLIQSQEDIRNPKVELKAERYS", "length": 309 }, "evidence": [ { "id": "A0A8V0YBU4", "url": "https://omabrowser.org/oma/group/A0A8V0YBU4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "lithium ion binding", "id": "GO:0031403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031403", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "sodium ion binding", "id": "GO:0031402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "pyridoxal kinase activity", "id": "GO:0008478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008478", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyridoxal 5'-phosphate salvage", "id": "GO:0009443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009443", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10224", "name": "", "equation": "pyridoxal + ATP = pyridoxal 5'-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "10224", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10224" } ] }, { "id": "25104", "name": "", "equation": "pyridoxamine + ATP = pyridoxamine 5'-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "25104", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25104" } ] }, { "id": "25108", "name": "", "equation": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "25108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25108" } ] }, { "id": "R-GGA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V0XQ57-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "O57535-1", "Q90835-1", "A0A8V0ZIP8-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "A0A8V0YHC8-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q02977-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y5M6-1", "A0A8V0YBU4-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798748" } ] }, { "id": "R-GGA-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XAC6-1", "A0A8V0XIL3-1", "A0A8V1AD74-1", "A0A8V1AMW1-1", "A0A8V0ZNL2-1", "Q8QFM7-1", "E1C9D9-1", "A0A8V0YW12-1", "A0A8V0ZJW2-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1", "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798749" } ] }, { "id": "R-GGA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-964945" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-964958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964958" } ] }, { "id": "R-GGA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-965053" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-964962", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964962" } ] }, { "id": "R-GGA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-965131" ], "output_participant_list": [ "R-ALL-29390" ], "enzyme_list": [ "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-964970", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964970" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29390", "participant_name": "PXLP [cytosol]", "crossref": [ { "id": "597326", "database": "ChEBI", "url": "" }, { "id": "C00018", "database": "COMPOUND", "url": "" }, { "id": "ZINC000001532514", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-964945", "participant_name": "PXA [cytosol]", "crossref": [ { "id": "16410", "database": "ChEBI", "url": "" }, { "id": "C00534", "database": "COMPOUND", "url": "" }, { "id": "ZINC000034926229", "database": "ZINC", "url": "" }, { "id": "HMDB0001431", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-965053", "participant_name": "PDX [cytosol]", "crossref": [ { "id": "16709", "database": "ChEBI", "url": "" }, { "id": "C00314", "database": "COMPOUND", "url": "" }, { "id": "ZINC000000049154", "database": "ZINC", "url": "" }, { "id": "HMDB0000239", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-965131", "participant_name": "PXL [cytosol]", "crossref": [ { "id": "17310", "database": "ChEBI", "url": "" }, { "id": "C00250", "database": "COMPOUND", "url": "" }, { "id": "ZINC000000120249", "database": "ZINC", "url": "" }, { "id": "HMDB0001545", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XAC6", "gene_name": "HPSE", "activity": [ { "ec_number": "3.2.1.166", "activity": "endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan.", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] }, { "ec_number": "3.2.1.166", "activity": "", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XIL3", "gene_name": "NIT2", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] } ] }, { "uniprot_ac": "A0A8V0XQ57", "gene_name": "APRT", "activity": [ { "ec_number": "2.4.2.7", "activity": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine.", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] }, { "ec_number": "2.4.2.7", "activity": "", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": 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Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040513972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513972" } ] }, { "annotation": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV3#function" }, { "database": "UniProtKB", "id": "ARBA00002025", "url": "https://www.uniprot.org/uniprotkb/ARBA00002025#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YBX8-1", "uniprot_ac": "A0A8V0YBX8", "uniprot_id": "A0A8V0YBX8_CHICK", "mass": { "chemical_mass": 42642.0, "monoisotopic_mass": 42642.0 }, "refseq": { "ac": "NP_001292081", "name": "stimulator of interferon genes protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" }, "gene_names": [ { "name": "TMEM173", "type": "recommended", "evidence": [ { "id": "A0A8V0YBX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8" } ] }, { "name": "STING1", "type": "synonym", "evidence": [ { "id": "NP_001292081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] }, { "name": "STING", "type": "synonym", "evidence": [ { "id": "NP_001292081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] }, { "name": "TMEM173", "type": "synonym", "evidence": [ { "id": "NP_001292081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] } ], "protein_names": [ { "name": "Stimulator of interferon genes protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YBX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8/entry#names_and_taxonomy" } ] }, { "name": "stimulator of IFN genes", "type": "synonym", "evidence": [ { "id": "NP_001292081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] }, { "name": "stimulator of interferon genes protein", "type": "synonym", "evidence": [ { "id": "NP_001292081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888496.12656.1, SRR12888547.147797.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000254.1. On Nov 16, 2021 this sequence version replaced NP_001292081.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ] }, { "annotation": "Cryo-electron microscopy structures of full-length STING from human and chicken in the inactive dimeric state (about 80 kDa in size), as well as cGAMP-bound chicken STING in both the dimeric and tetrameric states", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" }, { "database": "PubMed", "id": "30842659", "url": "https://glygen.org/publication/PubMed/30842659" } ] }, { "annotation": "IRF7 Is Involved in Both STING and MAVS Mediating IFN-beta Signaling in IRF3-Lacking Chickens.", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" }, { "database": "PubMed", "id": "31366714", "url": "https://glygen.org/publication/PubMed/31366714" } ] }, { "annotation": "Mutational analyses validate the interaction mode between TBK1 and STING and support a model in which high-order oligomerization of STING and TBK1, induced by cGAMP, leads to STING phosphorylation by TBK1", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" }, { "database": "PubMed", "id": "30842653", "url": "https://glygen.org/publication/PubMed/30842653" } ] }, { "annotation": "These results indicated that chSTING is an important regulator of chicken innate immune signaling and might be involved in the MDA5 signaling pathway in chicken cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" }, { "database": "PubMed", "id": "26392466", "url": "https://glygen.org/publication/PubMed/26392466" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM173", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8", "locus": { "chromosome": "13", "start_pos": 826133, "end_pos": 823186, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011969", "url": "https://www.ensembl.org/id/ENSGALG00010011969" } ] } } ], "crossref": [ { "id": "A0A8V0YBX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768990", "url": "https://www.ncbi.nlm.nih.gov/gene/768990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055434", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055434", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768990", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYGQAGF", "url": "https://omabrowser.org/oma/group/QYGQAGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBX8", "url": "https://www.orthodb.org/?gene=A0A8V0YBX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34339:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34339:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1834941", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1834941", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3134975", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134975", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3249367", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3249367", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34979", "url": "https://www.rhea-db.org/rhea/34979", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQDPSTRSSPARLLIPEPRAGRARHAACVLLAVCFVVLFLSGEPLAPITRRVCTQLAALQLGVLLKGCCCLAEEIFHLHSRHHGSLWQVLCSCFPPRWHLALLLVGGSAYLDPLEDNGHSPRLALTLSCLCQLLVLALGLQKLSAVEVSELTESSKKNVAHGLAWSYYIGYLKVVLPRLKECMEEISRTNPMLRAHRDTWKLHILVPLGCDIWDDLEKADSNIQYLADLPETILTRAGIKRRVYRHSLYVIRDKDNKLRPCVLEFASPLQTLCAMSQDDCAAFSREQRLEQARLFYRSLRDILGSSKECAGLYRLIAYEEPAEPESHFLSGLILWHLQQQQREEYMVQEELPLGTGSVELSLQVSSSDLPQPLRSDCP", "length": 379, "header": "tr|A0A8V0YBX8-1|A0A8V0YBX8_CHICK Isoform 1 of Stimulator of interferon genes protein OS=Gallus gallus OX=9031 GN=TMEM173 PE=3 SV=1 CANONICAL=A0A8V0YBX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX8/entry", "sequence": { "sequence": "MPQDPSTRSSPARLLIPEPRAGRARHAACVLLAVCFVVLFLSGEPLAPITRRVCTQLAALQLGVLLKGCCCLAEEIFHLHSRHHGSLWQVLCSCFPPRWHLALLLVGGSAYLDPLEDNGHSPRLALTLSCLCQLLVLALGLQKLSAVEVSELTESSKKNVAHGLAWSYYIGYLKVVLPRLKECMEEISRTNPMLRAHRDTWKLHILVPLGCDIWDDLEKADSNIQYLADLPETILTRAGIKRRVYRHSLYVIRDKDNKLRPCVLEFASPLQTLCAMSQDDCAAFSREQRLEQARLFYRSLRDILGSSKECAGLYRLIAYEEPAEPESHFLSGLILWHLQQQQREEYMVQEELPLGTGSVELSLQVSSSDLPQPLRSDCP", "length": 379, "header": "tr|A0A8V0YBX8-1|A0A8V0YBX8_CHICK Isoform 1 of Stimulator of interferon genes protein OS=Gallus gallus OX=9031 GN=TMEM173 PE=3 SV=1 CANONICAL=A0A8V0YBX8-1" }, "locus": { "chromosome": "13", "start_pos": 826021, "end_pos": 824066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028649.1", "url": "https://www.ensembl.org/id/ENSGALT00010028649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016462.1", "url": "https://www.ensembl.org/id/ENSGALP00010016462.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken STING Mediates Activation of the IFN Gene Independently of the RIG-I Gene.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2015-10-15", "authors": "Cheng Yuqiang, Sun Yingjie, Wang Hengan, Yan Yaxian, Ding Chan, Sun Jianhe", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ], "reference": [ { "type": "PubMed", "id": "26392466", "url": "https://glygen.org/publication/PubMed/26392466" } ] }, { "title": "Structural basis of STING binding with and phosphorylation by TBK1.", "journal": "Nature", "date": "2019", "authors": "Zhang C, Shang G, Gui X, Zhang X, Bai XC, Chen ZJ", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ], "reference": [ { "type": "PubMed", "id": "30842653", "url": "https://glygen.org/publication/PubMed/30842653" } ] }, { "title": "Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.", "journal": "Nature", "date": "2019", "authors": "Shang G, Zhang C, Chen ZJ, Bai XC, Zhang X", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ], "reference": [ { "type": "PubMed", "id": "30842659", "url": "https://glygen.org/publication/PubMed/30842659" } ] }, { "title": "IRF7 Is Involved in Both STING and MAVS Mediating IFN-\u03b2 Signaling in IRF3-Lacking Chickens.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2019-10-01", "authors": "Cheng Yuqiang, Zhu Wenxian, Ding Chan, Niu Qiaona, Wang Hengan, Yan Yaxian, Sun Jianhe", "evidence": [ { "database": "RefSeq", "id": "NP_001292081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292081" } ], "reference": [ { "type": "PubMed", "id": "31366714", "url": "https://glygen.org/publication/PubMed/31366714" } ] } ], "pathway": [ { "id": "gga:768990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768990", "resource": "KEGG Pathway" }, { "id": "R-GGA-1834941", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1834941", "resource": "Reactome", "description": "STING mediated induction of host immune responses" }, { "id": "R-GGA-3134975", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134975", "resource": "Reactome", "description": "Regulation of innate immune responses to cytosolic DNA" }, { "id": "R-GGA-3249367", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3249367", "resource": "Reactome", "description": "STAT6-mediated induction of chemokines" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N0V3-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "Sting1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYSSLHPSIPRPRGHRSKQAALVLLVASLMILWWLEDPPNHTLRYLVFYLASLQLGLLLKEICCLAEELCHVHSRYQSSYRKAVYACLGCPIRRMALLLLSIYFYCFLPSTTGLHLIWMLALLGLSQSLSILLGLQNLAPAEISAVCEKKNFNVAHGLAWSYYIGYLRLILPGLQARIRMFNQRHDNLLSGAGSRRLYILFPLDCGVPDDLSVADPNIRFRDMLPQQNMNRAGIKNRVYSNSVYELLEKGQPAGACILEYATPLQTLFAMSQDGKAGFSREDRLEQAKLFCRTLEDILDDVPETRNNCCLIVYQEPEEGNSFSLSQEVLRHIRQEEREEVAMSGPQTSVASHSSVLSQEPRLLISDMEQPLPLRTDLF", "length": 379 }, "evidence": [ { "id": "A0A8V0YBX8", "url": "https://omabrowser.org/oma/group/A0A8V0YBX8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F4N7-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "sting1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVMGEDALVPRARSRLPVMCAAGLGFLTLAVAWLLDSDKFSERAGIIAFGLMLERFIYCICLLAEELLFHSRQRYHGRMSEIFRACFRGSGILGMCAIFLMLMLGGVSFSVKQWSHFNLMCAGYMLLNSLGVLGPAPVEISEICEAKKMNVAHGLAWSFYIGYLKFLLPALEVNVREYSRRERLSSPRLHILLPLNARVPSKPEEEDTNVVFHENLPDLKLDRAGVRKRSYTNSVYKITHNNETFSCILEYATPLLTLYQMSQESSAGFGERERKQQVLLFYRTLSQILDNSLECRNRYRLILLNDEHTGDPHYLSRELFQNLKQQDGEIFMDPTNEVHPVPEEGPVGNCNGALQATFHEEPMSDEPTLMFSRPQSLRSEPVETTDYFNPSSAMKQN", "length": 398 }, "evidence": [ { "id": "A0A8V0YBX8", "url": "https://omabrowser.org/oma/group/A0A8V0YBX8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M391-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "Sting1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPYSNLHPSIPRPRSYRFKLAAFVLLVGSLMSLWMTGEPPSHTLHYLALHVASQQLGLLLKKLCCLAEELCHVQSRYQGSYWKAVRACVGSPICFMALILLSFYFYCSLENTSDLRLAWHLGILVLSKSLSMTLDLQSLAPAEVSAVCEEKNFNVAHGLAWSYYIGYLKLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDDLSVADPNIRFRDMLPQQNTDRAGVKNRAYSNSVYELLENGQPAGACILEYATPLQTLFAMSQDGKAGFSREDRLEQAKLFCRTLEEILADVPESRNHCRLIVYQESEEGNSFSLSQEVLRHIRQEEKEEVTMSGPPTSVAPRPSLLSQEPRLLISGMEQPLPLRTDLI", "length": 379 }, "evidence": [ { "id": "A0A8V0YBX8", "url": "https://omabrowser.org/oma/group/A0A8V0YBX8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KI99-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPHSSLHPSIPQPRGLRAQKAALVLLSACLVALWGLGEPPDYTLKWLVLHLASQQMGLLIKGICSLAEELCHVHSRYHGSYWRAVRACLCSSMRCGALLLLSCYFYCSLPNMADLPFTWMLALLGLSQALNILLGLQGLAPAEVSAICEKRNFNVAHGLAWSYYIGYLRLILPGLPARIQIYNQFHNNTLQGAGSHRLHILFPLDCGVPDDLNVADPNIRFLHELPQQSADRAGIKGRVYTNSIYELLENGQRAGVCVLEYATPLQTLFAMSQDGRAGFSREDRLEQAKLFCRTLEDILANAPESQNNCRLIVYQEPAEGSSFSLSQEILQHLRQEEREVTMGSTETSVMPGSSVLSQEPELLISGLEKPLPLRSDVF", "length": 378 }, "evidence": [ { "id": "A0A8V0YBX8", "url": "https://omabrowser.org/oma/group/A0A8V0YBX8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TBT3-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "Sting1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDLI", "length": 378 }, "evidence": [ { "id": "A0A8V0YBX8", "url": "https://omabrowser.org/oma/group/A0A8V0YBX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSGALP00010015154.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY9" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 258, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 219, "end_pos": 221 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCT5-1", "uniprot_ac": "A0A8V0YCT5", "uniprot_id": "A0A8V0YCT5_CHICK", "mass": { "chemical_mass": 67210.0, "monoisotopic_mass": 67210.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121108229", "type": "recommended", "evidence": [ { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ] } ], "protein_names": [ { "name": "Malic enzyme", "type": "recommended", "evidence": [ { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC37#function" }, { "database": "UniProtKB", "id": "ARBA00055709", "url": "https://www.uniprot.org/uniprotkb/ARBA00055709#function" }, { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5#function" }, { "database": "UniProtKB", "id": "A0A8V0YG79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG79#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121108229", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "121108229", "url": "https://www.ncbi.nlm.nih.gov/gene/121108229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ANYDTAN", "url": "https://omabrowser.org/oma/group/ANYDTAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC37", "url": "https://www.orthodb.org/?gene=A0A8V0YC37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCT5", "url": "https://www.orthodb.org/?gene=A0A8V0YCT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG79", "url": "https://www.orthodb.org/?gene=A0A8V0YG79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03949", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03949", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70268", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70268", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12653", "url": "https://www.rhea-db.org/rhea/12653", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "15641", "url": "https://www.rhea-db.org/rhea/15641", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSRFRLTLQRCVHTREKGKPLMLNPRTNKGMAFTLLERQMLGLQGLLPPKIETQDIQALRFHKNMAKMSDPLQKYIYLMGIQERNEKLFYRVLQDDIERLLPVVYTPTVGLACTQYGHIFRRPKGLFISISDRGHIRSVVNNWPENDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIHPHKCLPVCIDVGTDNTSLLKDPFYMGLYQKRDRSPAYDDLIDEFMEAITDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKATGKPIAEHKVLFLGAGEVLQGGDRVPKWGCFPPLSTPQPPSPPHNPPQAALGIANLIVMAMVENGVPVEDARRRIWMYDKHGLVRQGREEKVDSNQEPFAHPAPDSIPHSFEEAVTLLKPSAIIGVAGAGRLFTPSVLQKMAAINDRPIIFALSNPTAKAECTAEEAYTLTEGRCLFASGSPFDVVTLPDGRSFKAGQGNNAYIFPGVALAVILSSVRHISDRVFLEAAKALSEQLSPPDLAQGRLYPPLSHIREVSVCIAVRVMEFLYANGMAFHYPEPPEKEPYVRSKVWTSQYDSFVPDVYQWPRNAPS", "length": 603, "header": "tr|A0A8V0YCT5-1|A0A8V0YCT5_CHICK Isoform 1 of Malic enzyme OS=Gallus gallus OX=9031 GN=LOC121108229 PE=3 SV=1 CANONICAL=A0A8V0YCT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC37/entry", "sequence": { "sequence": "MLSRFRLTLQRCVHTREKGKPLMLNPRTNKGMAFTLLERQMLGLQGLLPPKIETQDIQALRFHKNMAKMSDPLQKYIYLMGIQERNEKLFYRVLQDDIERLLPVVYTPTVGLACTQYGHIFRRPKGLFISISDRGHIRSVVNNWPENDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIHPHKCLPVCIDVGTDNTSLLKDPFYMGLYQKRDRSPAYDDLIDEFMEAITDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKATGKPIAEHKVLFLGAGEAALGIANLIVMAMVENGVPVEDARRRIWMYDKHGLVRQGREEKVDSNQEPFAHPAPDSIPHSFEEAVTLLKPSAIIGVAGAGRLFTPSVLQKMAAINDRPIIFALSNPTAKAECTAEEAYTLTEGRCLFASGSPFDVVTLPDGRSFKAGQGNNAYIFPGVALAVILSSVRHISDRVFLEAAKALSEQLSPPDLAQGRLYPPLSHIREVSVCIAVRVMEFLYANGMAFHYPEPPEKEPYVRSKVWTSQYDSFVPDVYQWPRNAPS", "length": 572, "header": "tr|A0A8V0YC37-1|A0A8V0YCT5_CHICK Computationally mapped isoform of Malic enzyme OS=Gallus gallus OX=9031 GN=LOC121108229 PE=3 SV=1 CANONICAL=A0A8V0YCT5-1" }, "locus": { "chromosome": "Z", "start_pos": 94053, "end_pos": 55428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026662.1", "url": "https://www.ensembl.org/id/ENSGALT00010026662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015212.1", "url": "https://www.ensembl.org/id/ENSGALP00010015212.1" } ] } }, { "isoform_ac": "A0A8V0YCT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5/entry", "sequence": { "sequence": "MLSRFRLTLQRCVHTREKGKPLMLNPRTNKGMAFTLLERQMLGLQGLLPPKIETQDIQALRFHKNMAKMSDPLQKYIYLMGIQERNEKLFYRVLQDDIERLLPVVYTPTVGLACTQYGHIFRRPKGLFISISDRGHIRSVVNNWPENDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIHPHKCLPVCIDVGTDNTSLLKDPFYMGLYQKRDRSPAYDDLIDEFMEAITDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKATGKPIAEHKVLFLGAGEVLQGGDRVPKWGCFPPLSTPQPPSPPHNPPQAALGIANLIVMAMVENGVPVEDARRRIWMYDKHGLVRQGREEKVDSNQEPFAHPAPDSIPHSFEEAVTLLKPSAIIGVAGAGRLFTPSVLQKMAAINDRPIIFALSNPTAKAECTAEEAYTLTEGRCLFASGSPFDVVTLPDGRSFKAGQGNNAYIFPGVALAVILSSVRHISDRVFLEAAKALSEQLSPPDLAQGRLYPPLSHIREVSVCIAVRVMEFLYANGMAFHYPEPPEKEPYVRSKVWTSQYDSFVPDVYQWPRNAPS", "length": 603, "header": "tr|A0A8V0YCT5-1|A0A8V0YCT5_CHICK Isoform 1 of Malic enzyme OS=Gallus gallus OX=9031 GN=LOC121108229 PE=3 SV=1 CANONICAL=A0A8V0YCT5-1" }, "locus": { "chromosome": "W", "start_pos": 481459, "end_pos": 443846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028982.1", "url": "https://www.ensembl.org/id/ENSGALT00010028982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016741.1", "url": "https://www.ensembl.org/id/ENSGALP00010016741.1" } ] } }, { "isoform_ac": "A0A8V0YG79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG79/entry", "sequence": { "sequence": "MLSRFRLTLQRCVHTREKGKPLMLNPRTNKGMAFTLLERQMLGLQGLLPPKIETQDIQALRFHKNMAKMSDPLQKYIYLMGIQERNEKLFYRVLQDDIERLLPVVYTPTVGLACTQYGHIFRRPKGLFISISDRGHIRSVVNNWPENDVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIHPHKCLPVCIDVGTDNTSLLKDPFYMGLYQKRDRSPAYDDLIDEFMEAITDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKATGKPIAEHKVLFLGAGEAALGIANLIVMAMVENGVPVEDARRRIWMYDKHGLVRQGREEKVDSNQEPFAHPAPDSIPHSFEEAVTLLKPSAIIGVAGAGRLFTPSVLQKMAAINDRPIIFALSNPTAKAECTAEEAYTLTEGRCLFASGSPFDVVTLPDGRSFKAGQGNNAYIFPGVALAVILSSVRHISDRVFLEAAKVMEFLYANGMAFHYPEPPEKEPYVRSKVWTSQYDSFVPDVYQWPRNAPS", "length": 539, "header": "tr|A0A8V0YG79-1|A0A8V0YG79_CHICK Computationally mapped isoform of Malic enzyme OS=Gallus gallus OX=9031 GN=LOC121108229 PE=3 SV=1 CANONICAL=A0A8V0YCT5-1" }, "locus": { "chromosome": "Z", "start_pos": 94053, "end_pos": 55428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026659.1", "url": "https://www.ensembl.org/id/ENSGALT00010026659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015210.1", "url": "https://www.ensembl.org/id/ENSGALP00010015210.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-70268", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70268", "resource": "Reactome", "description": "Pyruvate metabolism" }, { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K502-1", "protein_name": "Malic enzyme", "gene_name": "Me2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKWHLCAGIGRREKMFSRLRAVTTPCTLTCRRVHLKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLKKYQEKYCTFNDDIQGTAAVALSGLLAAQRVINKPISEHRILFLGAGEAALGIAKLIVISMMESGLSEEEAQRKIWMFDKNGLLVKGRTARIDSNQEPYAHAASENIPATFEDAVNKLKPSVIIGVAGAGPLFTPGVIKAMAAINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVRLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTSQLTDEELAQGRLYPSLANIQEVSANIAIKIAEYLYANKMAFRYPEPEDKAKYVKERIWRSNYVSLLPDVYDWPESSLKPPQIPE", "length": 598 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5PN55-1", "protein_name": "Malic enzyme", "gene_name": "me2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSRLSTSVRPCVSMCRWVHTKEKGKPLMLNPRTNKGMAFTLKERQMLGIHGLLPSKIETQDTQAMRFQKNLKKMSDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIKDQGHIRSILDNWPDTSVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDVGTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQFEDFGNHNAFRFLKKYREKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALGIANLIVMAMMESGMSQADARKKIWMFDKYGLLVKDRAYETDSNQEAFVHPDPGDVKSFLDAVNVIKPTAIIGVSGAGRLFTHDVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPFAPVSLEDGRILTPGQGNNAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEELSQGRLYPPLSNIREVSLQMAIKVVEYVYSKGMAFRYPEPVDKESYVRSVVWNTNYDSFLPDIYDWPGVSHTPIVD", "length": 581 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" }, { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HTR9-1", "protein_name": "Malic enzyme", "gene_name": "Me2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSRVRAIVTPCTLTCRHLHLKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNKALLKDPFYMGLYQKRDRSQLYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALSGLLATQKVINKPVSEHKILFLGAGEAALGIANLIVMSMVESGLSEEEARRKVWMFDKNGLLVKGRSASIDSNQEPFAHGAPENVPGTFEDAVNKLKPSVIIGVAGAGRLFTPGVIKAMASINERPIIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCQTRHISDSVFLEAAKALTSQLTDEELAQGRLYPSLANIQEVSVNIAIKVTEYLYANKMAFRYPEPEDKAKYVKERIWRSDYVSLLPDVYDWPESSLKPPQISE", "length": 584 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P23368-1", "protein_name": "NAD-dependent malic enzyme, mitochondrial", "gene_name": "ME2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE", "length": 584 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6TU48-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "malA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQNKPSFILRNPSANKGTGFNNEEREKLGLKGLLPPKVESLQEQSDRALSQFTSFNTNLERYIFLNCLRDRNETLFYYLLSNNLELMMPIIYTPTVGEACQKFGNEFRFAQGMYFASQDKGNIRAMMDNWPAEGVDIIVVSDGSRILGLGDLGTNGMGIPVGKLQLYVAGAGFCPTRTLPVIIDSGTNTKKYLEDKYYLGERHPRIPDSEYYPLVDEFLAAAFNKWPKVIVQFEDISNDHCFNLLDEYRNKYLCFNDDIQGTGSVILSGFINAVRSVQKPIKEHRMVFLGAGSAGIGVADCIMSLFDEAGVSKEEARKSFWFVDSKGLITTTRGDELTSQKKQYAREDYTYQLKSLLEVVRDVKPTAIIGLSGIGGSFSQEVIEEMAKHVEKPIVFALSNPTTNAECTAEQAYQWTDGRCIFASGSPFKPVEYKGKTFVPGQGNNMYIFPGLGLAASVCEAKHVTDAMIITAAKTLASFVEDSEVLTGKIYPGLQHIREISTRIAVKVIEKAYEEGMAQLPRPDNIEALVKSRQYVPSYDKSKN", "length": 544 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99KE1-1", "protein_name": "NAD-dependent malic enzyme, mitochondrial", "gene_name": "Me2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLRAVTTPCTLTCRRVHLKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLLVKGRTASIDSNQEPYAHAAPESIPATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLTDAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYVRERIWRSNYVSLLPDVYDWPESSLTPPQITEEKLPH", "length": 589 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CA83-1", "protein_name": "NADP-dependent malic enzyme 4, chloroplastic", "gene_name": "NADP-ME4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MISLTPSLFLNKTVVPGCSTRLSLRQPRTIITPPASLRVFSSLGSNQDPTGSVLIETTATSSSSLETSAADIVPKSTVSGGVQDVYGEDAATEDMPITPWSLSVASGYTLLRDPHHNKGLAFSHRERDAHYLRGLLPPTVISQDLQVKKIMHTLRQYQVPLQKYMAMMDLQETNERLFYKLLIDHVEELLPVIYTPTVGEACQKYGSIFLRPQGLFISLKEKGKIHEVLRNWPEKNIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQRRATGEEYSELMHEFMTAVKQNYGEKVVIQFEDFANHNAFDLLAKYGTTHLVFNDDIQGTASVVLAGLIAALRFVGGSLSDHRFLFLGAGEAGTGIAELIALEISKKSHIPLEEARKNIWLVDSKGLIVSSRKESIQHFKKPWAHDHEPIRELVDAVKAIKPTVLIGTSGVGQTFTQDVVETMAKLNEKPIILSLSNPTSQSECTAEEAYTWSQGRAIFASGSPFAPVEYEGKTFVPGQANNAYIFPGFGLGLIMSGTIRVHDDMLLAASEALAEELMEEHYEKGMIYPPFRNIRKISARIAAKVAAKAYELGLATRLPQPKELEQCAESSMYSPSYRSYR", "length": 646 }, "evidence": [ { "id": "A0A8V0YCT5", "url": "https://omabrowser.org/oma/group/A0A8V0YCT5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NAD+) activity", "id": "GO:0004471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NADP+) activity", "id": "GO:0004473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004473", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12653", "name": "", "equation": "(S)-malate + NAD(+) = pyruvate + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12653", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12653" } ] }, { "id": "15641", "name": "", "equation": "oxaloacetate + H(+) = pyruvate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q92060-1", "F1NXZ7-1" ], "evidence": [ { "id": "15641", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15641" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1NXZ7", "gene_name": "FAHD1", "activity": [ { "ec_number": "3.7.1.5", "activity": "a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+).", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] }, { "ec_number": "4.1.1.112", "activity": "oxaloacetate + H(+) = pyruvate + CO2.", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] }, { "ec_number": "5.3.2.2", "activity": "oxaloacetate = enol-oxaloacetate.", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] }, { "ec_number": "4.1.1.112", "activity": "", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] }, { "ec_number": "3.7.1.5", "activity": "", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] }, { "ec_number": "5.3.2.2", "activity": "", "evidence": [ { "id": "F1NXZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXZ7" } ] } ] }, { "uniprot_ac": "Q92060", "gene_name": "ME1", "activity": [ { "ec_number": "1.1.1.40", "activity": "(S)-malate + NADP(+) = pyruvate + CO2 + NADPH.", "evidence": [ { "id": "Q92060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92060" } ] }, { "ec_number": "1.1.1.40", "activity": "", "evidence": [ { "id": "Q92060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92060" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" }, { "id": "SM01274", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01274" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malic enzyme N-terminal", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 264, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" }, { "id": "SM00919", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malic enzyme NAD-binding", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 560, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "binding_site_uniprot": 249, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 249, "end_pos": 249, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "binding_site_uniprot": 250, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 250, "end_pos": 250, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR000106-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000106-3" }, { "id": "A0A8V0YCT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT5" } ], "binding_site_uniprot": 273, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 273, "end_pos": 273, "start_aa": "Asp", "end_aa": "Asp", 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"length": 2005, "header": "tr|A0A8V0YC42-1|A0A8V0YC42_CHICK Isoform 1 of Doublecortin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42/entry", "sequence": { "sequence": "MTQVPADYLSTTSSYNYDQPLPSVGRTSTVTQVPPAKKITFFKSGDPQFGGVKMAINQRSFKSFNALMDDLSHRVPLPFGVRTITTPRGIHCISELDQLEDGGCYLCSDKKYVKPINITTAGHRPGPPRNGRPSSTLRRAAQEGRLDDYSTPFTQHGPRIPKKITLVKNGETSFRRSIILNRRNARSFKTLLDEISEILQFPVKKLFTVDGKKIDSMQALLHCPNVLVCVGREPFKPVSMENLRKHSVENHFKQWGTNTKKSVIHPRSASSNRSMRFSLSSEKSYPNGLAASPDNGAPFCPHSKPGDLVHSLVNDDIEKRVHVNKDGSLSVEMKVRFRLLNDETLQWSTQIKKSNLMNRMPCEESGLEEDSGVDPIQKMNPEASSEADDSLYPCDVDSYMSKLEESECDEAHCHSCGKKHQDYDIWKNPMHASQREEPSVRSTWHTRSSCSSTSSRRRVIHKKKASVDSLRTTSSEEFSEHIVHESSSYSETIENRVAYRSIKKCTCRSDLSTGASNGEDQQEYTRTSTSNSQRPSSLGLMSHSSCENNLDTQEAPEDYEASKTNSQKEDENCFEISSVKCLKDDAEEAESSRVGSIISRSSVQSRQSKNICEETSSVGRTMSSSSLQKANEGDNTMCSTPANSVHSRSSNCSTPRAKSEHDDNSENNAVVSSFSSESCPKKEAEEIEEEENEVNEISSVSTNTKPNQSGKDESSEGEQCSAPGTPQSIASVRNSRRSDSNEIVPCNASCSSKGSKKSKYSHLYLDAQSEMSVSSLESTQNKKKNSLHAEELRSCSRVSNYSKSSCEIKKRSIGDPMSHNSGSFQSNISSTSEAEAIAITTEEKSSKSTTNGYSASSKGSKRGSHREENSKASSLCSSVSGPSRKAGEGHSKMNSEAHSSRHGSISESVCSKGDHLTETGIRNGNPESVSSRVSSKSEVEDKRLLTQVSQESDGRCSQSNMSQSSKSRQNKSRNLNVAMSNSSRASPSETMSICSKHFPAPPKGKPNSKKPRSAILKNSSISSIGTESVFTTGRQQKDVVDSSKPTSFGSKSVATEANDQKNTKLNGSCSGKVEEVLEDTGVQEEWSGLMPSSLPNTSPEEVVQEWLSKIPSETLLMKYEMEDNAEEECIEAITEISCCTNAEEIPEDEKGEEKNAAEAENEAVDEVEKETVEVIAVNEEAEEYANQEQIPEVMSEAVKADQAECSQSVTSSQNNNKKDLPTSVQTSVQIMKALLSSKHEAKFDRSNSLPEVSPTMGRKLSNSATVLITCLASLQLLDEESEDPSDKSKCLNKPRYMELLNIFQALWFGQTAEKSGPSSGQEASGQEKSASGFKVPKSVNGDFTPMSSSGVDVSSGSGGSGEEITAGAKDCNLLAQKTVEFKSDGQAEDGETATELTETEEQSKQEEHSSRPSTACSKSKGEEKENSTREESLLQDQCSNCENDQEKGEENENTENSRLVENGEKEEAEAVNEALLKENLEEAADQLSTTIETNVSDADCGTELKADIQEQLEKGSTKDPEPKVDTATSMGTSLVQQNSVDPDPVWVLRLLKKIEKEFMAHYVNAMNELKVRWNLQNNQQMDEMILELKEEVSKRIQRSIEKELKKIKSRAGTKMPRPPDGPLKRESTLQTEQRRRRLQTMHKKSFFSDKTGTHSRLADTSDLSLDVDEDTAFSAAFEASISEQPSEEEYCPCDACVRKKMASKPARNPVVATNAPVVKAFDLQQILRRKKDENEEACVSEAAQDNKATPSSNVEEAEETKEVEEEEEEKAEDITLKAEEEEETKEEVEGETKEEEEGKEEEEETKEEEQEEEEEIKEEEEGKEEEEETKEEEQEEEEEIKEEEEEGKEEEEETREEEEGKEEEEEGKEEEEETKEEEQEEEEEIKEEEEEGKEEEEETREEEEGKEEEEEGKEEEEETKEEEQEEEEEIKEEEEEGKEEEEETREEEEGKEEEEEGKEEEEETKEEEEKEEGKAEEEEVNEEEETKEEGEGKEEEEEVNEEEET", "length": 2005, "header": "tr|A0A8V0YC42-1|A0A8V0YC42_CHICK Isoform 1 of Doublecortin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC42-1" }, "locus": { "chromosome": "3", "start_pos": 106571729, "end_pos": 106547854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026677.1", "url": "https://www.ensembl.org/id/ENSGALT00010026677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015217.1", "url": "https://www.ensembl.org/id/ENSGALP00010015217.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1255, "start_aa": "Thr", "end_pos": 1255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1255", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" }, { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1018, "end_pos": 1020, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1066, "end_pos": 1068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1494, "end_pos": 1496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": 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4a-hydroxytetrahydrobiopterin dehydratase OS=Gallus gallus OX=9031 GN=PCBD2 PE=3 SV=1 CANONICAL=A0A8V0YC59-1" }, "locus": { "chromosome": "13", "start_pos": 15270795, "end_pos": 15254467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031460.1", "url": "https://www.ensembl.org/id/ENSGALT00010031460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018367.1", "url": "https://www.ensembl.org/id/ENSGALP00010018367.1" } ] } }, { "isoform_ac": "A0A8V0YII8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII8/entry", "sequence": { "sequence": "VRNVSLKPACSDIESNSPPAHFSSQSHWLTAEERTQVLLDLKASGWSESGERDAIYKEFNFKNFNQAFGFMTRVALQAEKMNHHPEWFNVYSKVQITLISHDCGGLTKRDVKLAQFIDKAAASV", "length": 124, "header": "tr|A0A8V0YII8-1|A0A8V0YII8_CHICK Computationally mapped isoform of 4a-hydroxytetrahydrobiopterin dehydratase OS=Gallus gallus OX=9031 GN=PCBD2 PE=3 SV=1 CANONICAL=A0A8V0YC59-1" }, "locus": { "chromosome": "13", "start_pos": 15270087, "end_pos": 15254467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031455.1", "url": "https://www.ensembl.org/id/ENSGALT00010031455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018364.1", "url": "https://www.ensembl.org/id/ENSGALP00010018364.1" } ] } }, { "isoform_ac": "A0A8V0YKI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI8/entry", "sequence": { "sequence": "MRWFSYSIRKQQSMRRGWRMPSPACCSPWLLFILRVKAFGFMTRVALQAEKMNHHPEWFNVYSKVQITLISHDCGGLTKRDVKLAQFIDKAAASV", "length": 95, "header": "tr|A0A8V0YKI8-1|A0A8V0YKI8_CHICK Computationally mapped isoform of 4a-hydroxytetrahydrobiopterin dehydratase OS=Gallus gallus OX=9031 GN=PCBD2 PE=3 SV=1 CANONICAL=A0A8V0YC59-1" }, "locus": { "chromosome": "13", "start_pos": 15268746, "end_pos": 15254467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031449.1", "url": "https://www.ensembl.org/id/ENSGALT00010031449.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018360.1", 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147332.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDE3A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57", "locus": { "chromosome": "1", "start_pos": 65179434, "end_pos": 64942643, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011688", "url": "https://www.ensembl.org/id/ENSGALG00010011688" } ] } } ], "crossref": [ { "id": "A0A8V0YC57", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YC57", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00077", 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and Pathway" ] }, { "id": "CIPREQI", "url": "https://omabrowser.org/oma/group/CIPREQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC57", "url": "https://www.orthodb.org/?gene=A0A8V0YC57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14653", "url": "https://www.rhea-db.org/rhea/14653", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16957", "url": "https://www.rhea-db.org/rhea/16957", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25277", "url": "https://www.rhea-db.org/rhea/25277", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAVTSAARTTSLVALERVPASWRPYLAYLLGLLGVLLAGYAERLWPPRRAAPLAEPPAAPPAADEAPALRRRRRSSSMISAEMSGGGGGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRTVSNLLNTQLTFQAIHKPRVNPLVSFSENYTCSDSEECPEKGEKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHESSSSSTDSWNSSLLMTITKSRSFSTSYAMSPTNHLNAKRQSRQGIPPNISPLTSPCHSPLQGTPATSPTGKTSSVSFPDSTDTDTKQGLKPHKVLTATQSAPSLSEPNISPSVICSSCGRPYNQIEAGDGTLDRSDGTTHTLNRTDDPAQATSDYETNNSDSSDIVQNDDETDCSKEKARKGSVCRTYAPETIILHPLIPPEDKPVLAPEPLVMDNLDPLMEQLNSWNFPIFDLVEKIGKKCGRILSQVSYRLFEDMGLFETFKIPVREFMNYFHALECGYREIPYHNRIHATDVLHAVWYLTTQPIPGLPTVINDHGSASDSDSDSGITHGHMGYVFSKTYTPTDDSYGCLAGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDLHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLAHLQESFITHIVGPLCNSYDSAGLMPGKWIEDSDESGDTDEHEEEETAEMETCENAESRKKKFKRRKIYCQITQHLLQNHKMWKKVIEDEERLAGTEKQGAEQSTLHPSSEQIQAIREEDEEKGKPKRDEEENTTVEPNQ", "length": 928, "header": "tr|A0A8V0YC57-1|A0A8V0YC57_CHICK Isoform 1 of Phosphodiesterase OS=Gallus gallus OX=9031 GN=PDE3A PE=1 SV=1 CANONICAL=A0A8V0YC57-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57/entry", "sequence": { "sequence": "MLAVTSAARTTSLVALERVPASWRPYLAYLLGLLGVLLAGYAERLWPPRRAAPLAEPPAAPPAADEAPALRRRRRSSSMISAEMSGGGGGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRTVSNLLNTQLTFQAIHKPRVNPLVSFSENYTCSDSEECPEKGEKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHESSSSSTDSWNSSLLMTITKSRSFSTSYAMSPTNHLNAKRQSRQGIPPNISPLTSPCHSPLQGTPATSPTGKTSSVSFPDSTDTDTKQGLKPHKVLTATQSAPSLSEPNISPSVICSSCGRPYNQIEAGDGTLDRSDGTTHTLNRTDDPAQATSDYETNNSDSSDIVQNDDETDCSKEKARKGSVCRTYAPETIILHPLIPPEDKPVLAPEPLVMDNLDPLMEQLNSWNFPIFDLVEKIGKKCGRILSQVSYRLFEDMGLFETFKIPVREFMNYFHALECGYREIPYHNRIHATDVLHAVWYLTTQPIPGLPTVINDHGSASDSDSDSGITHGHMGYVFSKTYTPTDDSYGCLAGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDLHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLAHLQESFITHIVGPLCNSYDSAGLMPGKWIEDSDESGDTDEHEEEETAEMETCENAESRKKKFKRRKIYCQITQHLLQNHKMWKKVIEDEERLAGTEKQGAEQSTLHPSSEQIQAIREEDEEKGKPKRDEEENTTVEPNQ", "length": 928, "header": "tr|A0A8V0YC57-1|A0A8V0YC57_CHICK Isoform 1 of Phosphodiesterase OS=Gallus gallus OX=9031 GN=PDE3A PE=1 SV=1 CANONICAL=A0A8V0YC57-1" }, "locus": { "chromosome": "1", "start_pos": 65177925, "end_pos": 64942753, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027962.1", "url": "https://www.ensembl.org/id/ENSGALT00010027962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016045.1", "url": "https://www.ensembl.org/id/ENSGALP00010016045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418185", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418185", "resource": "KEGG Pathway" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B8Q1-1", "protein_name": "Phosphodiesterase", "gene_name": "pde3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALESVRNGYVRTCVTPVEQDCWHSCLRSRRSLSSAVCVASLSVLLALLWDAERTHAHSGSHLVTLVELVWQLLSPVLTLVCAFFWVGVYLLRCGVLIRTAVFLLTVCHLGEAAAQSLLDAQQLYSFTATALVLLACLASGALMVVRLGQGISVLLFISIIRTVSLLSLQKVRASWRPYLAYLLGLLGVLLARYADRLLPEQGASHREGSRGDIPVFKRRRRSSSVVSSDMAQHGQSRSKSHRRTSLPCLQREQMLPQQEWDNKRGARGSQQPSGLMQSSGTSVTVDIAVMGEAHGLISDLLADQSLAPNICSTLRAVSNLLNTQLTFQPLHHRPRLGPLLAFSDGHTCSDSEEAPEKGERLAIPKRLRRSLHPGLLRRISSTWTTTTSATGLPTLEPGPVRRDRSASIKAPHDGPSSSLVNSDSWNNSNMLSISKSRSMSASYAASSNTTNHIYSKSRRGCSSSTISPLASPCHSPPVQSSPLTSPTNKTPSVELPDPELPPPRSPHKALTHSQSAPSSSAALWPPPTPLCSSCGRPYSKQRHSDGSTEPAERTQQSDEPAMMSSDYDSTYETNHSDSSDFAQTDEDREARRTLTLATLIPAEEKPILAPEPLLMEGLEPLLCQINNWNFPIFSLVEKTNGRCGCILSQMSYRLFVDTGLFETFKIPVREFMNYFHALENGYRDIPYHNRIHATDVLHAVWYLTTQPVPGLPTLRTLGSSDSDSGLAHGRMKYLMSRTNAVEEEGYGCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAASAWNLFMSRPEYNFLASLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKVGDDGCSGIDWTNENDRLLVCQMCIKLADINGPLKCKDLHLQWTEGIVNEFYEQGDEESSLGLPISPFMDRSAPQLAKLQESFITHIVGPLCSSYDSAALMPGRWVHPLPKDGDEVEDESEEEDEDTAEEEEEDASTSSELSQKPAPKKRRKVFCQISHHLLENHEMWKKVIAEESQSQTEGEESTCLSTTPEPILAIDEEEEEPGSKEEPTDDQGEGSTEEEEGPVPEDTHETQEPDGETVEEADEKNTETVEDIEGKQDEDQKDPE", "length": 1124 }, "evidence": [ { "id": "A0A8V0YC57", "url": "https://omabrowser.org/oma/group/A0A8V0YC57/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L6S5-1", "protein_name": "Phosphodiesterase", "gene_name": "PDE3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPGKAARVGAKPGHGEARPAPADGRDKHPRVATAPPRDSGCRGCWGDLVLRPLRRCRKLSSALYAGSLSFLLALLVRLVRGEIGCDLERSKEAAAAAEEEEAAPGAEGGVFPGPRGGAPGGGAPLGPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAYLAGVLGILLARYVEQILPQSAGAAPREHFGSQLLAGTKEDIPVFKRRRRSSSVVSAEMSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPAVSFSENYTCSDSEESAEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSAINPDSWKNPVMMTLTKSRSFTSSYAVSASNHVKAKKQSRPGSLVKISPLSSPCSSPLQGTPASSPVSKISTVQFPEPADATAKQGLSSHKALTYTQSAPDLSPHILTPPVICSSCGRPYSQGNPADGPLERSGPAIQAQSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECSREPLRKASACSAYTPDTMMFLDKPILAPEPLVMDNLDSIMEHLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRTEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDEVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGDTDDPEEEEEEEEAPKEEETCENNDSPRKKTFKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIESQSLDQAPQQHSSEQIQAIKEEDEDKGKPRGEETPTPKPNQ", "length": 1145 }, "evidence": [ { "id": "A0A8V0YC57", "url": "https://omabrowser.org/oma/group/A0A8V0YC57/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14432-1", "protein_name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "gene_name": "PDE3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPGDAARVRDKPVHSGVSQAPTAGRDCHHRADPASPRDSGCRGCWGDLVLQPLRSSRKLSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAAEEEEAAPGAEGGVFPGPRGGAPGGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAYLAGVLGILLARYVEQILPQSAEAAPREHLGSQLIAGTKEDIPVFKRRRRSSSVVSAEMSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWNNPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYAPETMMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQAIKEEEEEKGKPRGEEIPTQKPDQ", "length": 1141 }, "evidence": [ { "id": "A0A8V0YC57", "url": "https://omabrowser.org/oma/group/A0A8V0YC57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62865-1", "protein_name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "gene_name": "Pde3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRGEAAQDWAKPGLRGPSPAPVARGDHRCRGGSPSSPRGSGCCWRALALQPLRRSPQLSSALCAGSLSVLLALLVRLVGGEVGGELESSQEAAAEEEEEEGARGGVFPGPRGGAPGGGAQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDGRLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVALTSALRTVALVSLERFKVAWRPYLAYLAAVLGLLLARYAEQLLPQCSGPAPPRERFGSQSSARTKEEIPGWKRRRRSSSVVAGEMSGCGGKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQSGTSVTVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWNAPVLMTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLDKISPVPSPSSSPPQGSPTSSPVSGIASVQFPESPEVTTKRGPGSHRALTYTQSAPDLSPQIPPSPVICSSCGRPYSQGNPADGPSERSGPAMQKPNRTDDTSQVTSDYETNNNSDSSDILQNDEEAECQREPLRKASACGTYTPQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIGDHGSASDSDSDSGFTHGHMGYVFSKAYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDLHLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKWVDDSDDSGDTDDPEEEEEEAETPHEEETCENSEAPRKKSFKRRRIYCQITQHLLQNHMMWKKVIEEEQCLSGTENQAPDQAPLQHSSEQIQAIKEEEEEKGKPRAEETLAPQPDL", "length": 1141 }, "evidence": [ { "id": "A0A8V0YC57", "url": "https://omabrowser.org/oma/group/A0A8V0YC57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0X4-1", "protein_name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", "gene_name": "Pde3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVRGEAAQDLAKPGLGGASPARVARGNHRHRGESSPSPRGSGCCWRALALQPLRRSPQLSSALCAGSLSVLLALLVRLVGGEVGGELEKSQEAAAEEEEEEGARGGVFPGPRGGAPGGGAQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDGRLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVAWTSVLRTVALVSLERFKVAWRPYLAYLAAVLGLLLARYAEQILPQCSGPAPPRERFGSQLSARTKEEIPGWKRRRRSSSVVAGEMSGCSGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKQAISKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWNAPGLTTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLAKISPVPSPSSSPPQGSPASSPVSNSASQQFPESPEVTIKRGPGSHRALTYTQSAPDLSPQIPPPSVICSSCGRPYSQGNPADGPSERSGPAMLKPNRTDDTSQVTSDYETNNNSDSSDILQNEEEAECQREPQRKASACGTYTSQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLMENIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIGDHGSASDSDSDSGFTHGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKWVDDSDDSGDTDDPEEEEEEAETPHEDEACESSIAPRKKSFKRRRIYCQITQHLLQNHMMWKKVIEEEQCLSGTENQSLDQVPLQHPSEQIQAIKEEEEEKGKPRAEETLAPQPDL", "length": 1141 }, "evidence": [ { "id": "A0A8V0YC57", "url": "https://omabrowser.org/oma/group/A0A8V0YC57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "nuclear estrogen receptor activity", "id": "GO:0030284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "estrogen binding", "id": "GO:0099130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of vascular permeability", "id": "GO:0043116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "positive regulation of vascular permeability", "id": "GO:0043117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "cellular response to cGMP", "id": "GO:0071321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0106072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14653", "name": "", "equation": "a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U726-1", "A0A8V0ZHM1-1", "A0A8V0ZVD4-1", "A0A8V0XWK8-1", "A0A8V0YC57-1", "A0A8V0ZTR9-1" ], "evidence": [ { "id": "14653", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14653" } ] }, { "id": "16957", "name": "", "equation": "3',5'-cyclic GMP + H2O = GMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U726-1", "A0A8V0ZHM1-1", "P52731-1", "A0A8V0ZVD4-1", "A0A8V0XWK8-1", "A0A8V0YC57-1", "E1BZ04-1", "A0A8V0ZTR9-1", "A0A8V0ZWY1-1" ], "evidence": [ { "id": "16957", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16957" } ] }, { "id": "25277", "name": "", "equation": "3',5'-cyclic AMP + H2O = AMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A706-1", "A0A3Q2U726-1", "A0A8V0ZHM1-1", "A0A8V0ZVD4-1", "A0A1D5PP20-1", "A0A8V1ADY1-1", "A0A8V0XWK8-1", "A0A8V0XFR6-1", "A0A8V0Y8J0-1", "A0A3Q2TZX9-1", "A0A8V0YC57-1", "A0A8V0ZTR9-1", "A0A8V0ZWY1-1" ], "evidence": [ { "id": "25277", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25277" } ] }, { "id": "R-GGA-9629675", "name": "PDE3A hydrolyses cAMP to AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YC57-1" ], "evidence": [ { "id": "R-GGA-9629675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629675" } ] }, { "id": "R-GGA-9629679", "name": "PDE3A inhibitors bind PDE3A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YC57-1" ], "evidence": [ { "id": "R-GGA-9629679", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629679" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PP20", "gene_name": "PDE4D", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A1D5PP20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP20" } ] } ] }, { "uniprot_ac": "A0A3Q2TZX9", "gene_name": "PDE7B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A3Q2TZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZX9" } ] }, { "ec_number": "3.1.4.53", "activity": "3',5'-cyclic AMP + H2O = AMP + H(+).", "evidence": [ { "id": "A0A3Q2TZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZX9" } ] }, { "ec_number": "3.1.4.53", "activity": "", "evidence": [ { "id": "A0A3Q2TZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZX9" } ] } ] }, { "uniprot_ac": "A0A3Q2U726", "gene_name": "PDE1B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A3Q2U726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U726" } ] } ] }, { "uniprot_ac": "A0A8V0XFR6", "gene_name": "PDE7A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0XFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR6" } ] } ] }, { "uniprot_ac": "A0A8V0XWK8", "gene_name": "PDE10A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0XWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWK8" } ] } ] }, { "uniprot_ac": "A0A8V0Y8J0", "gene_name": "PDE8B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0Y8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8J0" } ] } ] }, { "uniprot_ac": "A0A8V0YC57", "gene_name": "PDE3A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0YC57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC57" } ] } ] }, { "uniprot_ac": "A0A8V0ZHM1", "gene_name": "", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZHM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR9", "gene_name": "PDE3B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZTR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR9" } ] } ] }, { "uniprot_ac": "A0A8V0ZVD4", "gene_name": "PDE1A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVD4" } ] } ] }, { "uniprot_ac": "A0A8V0ZWY1", "gene_name": "PDE11A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWY1" } ] } ] }, { "uniprot_ac": "A0A8V1A706", "gene_name": "PDE4B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V1A706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A706" } ] } ] }, { "uniprot_ac": "A0A8V1ADY1", "gene_name": "PDE4C", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V1ADY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADY1" } ] } ] }, { "uniprot_ac": "E1BZ04", "gene_name": "PDE9A", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "E1BZ04", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_425472.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425472" } ] }, { "annotation": "Plays a role in endocytic trafficking. 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], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ICB4-1", "protein_name": "Sesquipedalian-2", "gene_name": "PHETA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP", "length": 259 }, "evidence": [ { "id": "A0A8V0YC83", "url": "https://omabrowser.org/oma/group/A0A8V0YC83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC83" } ], "pmid": "" }, { 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"PTHR46276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46276:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46276:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YC92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNSDGSKLSSGSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSIIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNAPVQSPVSLGEDLQWWPDKDGTKFISIGALYSELVAVNSKGELYQWKWSESEPYRNAQNPSLHHPRAMFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENNLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQEPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQSSSNSDPDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERSVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLTNLPANSTIKKKAAIIIMAVEKQTLMQHILRCDFEACRQYLMNLEQAVVLDQNPQVLQTFLGHRCDGNRNILHACVSVCFPTSNKETKEEEGLPHSVHKMDGAHRMEAERSERNTFAERLSAVEAIANAISVVSSNGPGSRAGSSSSRSLRLREMMRRSLRAAGLGRQEAGASSSDHQDPVSPPIAPPSWVPDPPAIDTDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEATSSEKEDDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTTTNLVTMPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTANPEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIIPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDMEQETFMLDEPLERTTNSSHATGAAQAPRSMQWAVRNTQNQRTTSTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGLDNEDSEHENDDDTNQSAALNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSANSGKCLMEVTVDRNCLEVLPTKMSYAANLKNVMSMQNRQKREGEEQNVPTEESESSKPGPSAHDLAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLTLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSDKVQENRKRHGSSRSVVDMELDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSTDADAVFAAMDLAFAIDLCKEEGGGQVELISNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "length": 2807, "header": "tr|A0A8V0YDJ7-1|A0A8V0YDJ7_CHICK Isoform 1 of E3 ubiquitin-protein ligase UBR5 OS=Gallus gallus OX=9031 GN=UBR5 PE=1 SV=1 CANONICAL=A0A8V0YDJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC92/entry", "sequence": { "sequence": "MQENVDSVVRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNSDGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSIIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNAPVQSPVSLGEDLQWWPDKDGTKFISIGALYSELVAVNSKGELYQWKWSESEPYRNAQNPSLHHPRAMFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENNLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQEPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQSSSNSDPDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERSVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLTNLPANSTIKKKAAIIIMAVEKQTLMQHILRCDFEACRQYLMNLEQAVVLDQNPQVLQTFLGHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNGPGSRAGSSSSRSLRLREMMRRSLRAAGLGRQEAGASSSDHQDPVSPPIAPPSWVPDPPAIDTDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEATSSEKEDDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTTTNLVTMPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTANPEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIIPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDMEQETFMLDEPLERTTNSSHATGAAQAPRSMQWAVRNTQNQRTTSTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGLDNEDSEHENDDDTNQSAALNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSANSGKCLMEVTVDRNCLEVLPTKMSYAANLKNVMSMQNRQKREGEEQNVPTEESESSKPGPSAHDLAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLTLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSDKVQENRKRHGSSRSVVDMELDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSTDADAVFAAMDLAFAIDLCKEEGGGQVELISNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "length": 2741, "header": "tr|A0A8V0YC92-1|A0A8V0YDJ7_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase UBR5 OS=Gallus gallus OX=9031 GN=UBR5 PE=1 SV=1 CANONICAL=A0A8V0YDJ7-1" }, "locus": { "chromosome": "2", "start_pos": 128752183, "end_pos": 128686407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028806.1", "url": "https://www.ensembl.org/id/ENSGALT00010028806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016574.1", "url": "https://www.ensembl.org/id/ENSGALP00010016574.1" } ] } }, { "isoform_ac": "A0A8V0YDJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7/entry", "sequence": { "sequence": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNSDGSKLSSGSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSIIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNAPVQSPVSLGEDLQWWPDKDGTKFISIGALYSELVAVNSKGELYQWKWSESEPYRNAQNPSLHHPRAMFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENNLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQEPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQSSSNSDPDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERSVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLTNLPANSTIKKKAAIIIMAVEKQTLMQHILRCDFEACRQYLMNLEQAVVLDQNPQVLQTFLGHRCDGNRNILHACVSVCFPTSNKETKEEEGLPHSVHKMDGAHRMEAERSERNTFAERLSAVEAIANAISVVSSNGPGSRAGSSSSRSLRLREMMRRSLRAAGLGRQEAGASSSDHQDPVSPPIAPPSWVPDPPAIDTDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEATSSEKEDDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTTTNLVTMPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTANPEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIIPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDMEQETFMLDEPLERTTNSSHATGAAQAPRSMQWAVRNTQNQRTTSTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGLDNEDSEHENDDDTNQSAALNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSANSGKCLMEVTVDRNCLEVLPTKMSYAANLKNVMSMQNRQKREGEEQNVPTEESESSKPGPSAHDLAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLTLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSDKVQENRKRHGSSRSVVDMELDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSTDADAVFAAMDLAFAIDLCKEEGGGQVELISNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "length": 2807, "header": "tr|A0A8V0YDJ7-1|A0A8V0YDJ7_CHICK Isoform 1 of E3 ubiquitin-protein ligase UBR5 OS=Gallus gallus OX=9031 GN=UBR5 PE=1 SV=1 CANONICAL=A0A8V0YDJ7-1" }, "locus": { "chromosome": "2", "start_pos": 128764903, "end_pos": 128686407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028811.1", "url": "https://www.ensembl.org/id/ENSGALT00010028811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016577.1", "url": "https://www.ensembl.org/id/ENSGALP00010016577.1" } ] } }, { "isoform_ac": "A0A8V0YFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR9/entry", "sequence": { "sequence": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNSDGSKLSSGSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSIIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNAPVQSPVSLGEDLQWWPDKDGTKFISIGALYSELVAVNSKGELYQWKWSESEPYRNAQNPSLHHPRAMFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENNLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQEPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQSSSNSDPDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERSVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLTNLPANSTIKKKAAIIIMAVEKQTLMQHILRCDFEACRQYLMNLEQAVVLDQNPQVLQTFLGHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNGPGSRAGSSSSRSLRLREMMRRSLRAAGLGRQEAGASSSDHQDPVSPPIAPPSWVPDPPAIDTDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEATSSEKEDDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTTTNLVTMPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTANPEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIIPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDMEQETFMLDEPLERTTNSSHATGAAQAPRSMQWAVRNTQNQRTTSTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGLDNEDSEHENDDDTNQSAALNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSANSGKCLMEVTVDRNCLEVLPTKMSYAANLKNVMSMQNRQKREGEEQNVPTEESESSKPGPSAHDLAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLTLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSDKVQENRKRHGSSRSVVDMELDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSTDADAVFAAMDLAFAIDLCKEEGGGQVELISNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "length": 2792, "header": "tr|A0A8V0YFR9-1|A0A8V0YFR9_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase UBR5 OS=Gallus gallus OX=9031 GN=UBR5 PE=1 SV=1 CANONICAL=A0A8V0YDJ7-1" }, "locus": { "chromosome": "2", "start_pos": 128764903, "end_pos": 128686407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028821.1", "url": "https://www.ensembl.org/id/ENSGALT00010028821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016583.1", "url": "https://www.ensembl.org/id/ENSGALP00010016583.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1745, "start_aa": "Thr", "end_pos": 1745, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1745", 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}, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ7" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDJ7", "url": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCA1-1", "uniprot_ac": "A0A8V0YCA1", "uniprot_id": "A0A8V0YCA1_CHICK", "mass": { "chemical_mass": 39563.0, "monoisotopic_mass": 39563.0 }, "refseq": { "ac": "XP_015149021", "name": "WD repeat-containing protein 55", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149021" }, "gene_names": [ { "name": "WDR55", "type": "recommended", "evidence": [ { "id": "A0A8V0YCA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ] }, { "name": "WDR55", "type": "synonym", "evidence": [ { "id": "XP_015149021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149021" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 55", "type": "recommended", "evidence": [ { "id": "A0A8V0YCA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 55", "type": "synonym", "evidence": [ { "id": "XP_015149021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149021" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149021.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149021" } ] }, { "annotation": "Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1#function" }, { "database": "UniProtKB", "id": "PIRNR038169", "url": "https://www.uniprot.org/uniprotkb/PIRNR038169#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1", "locus": { "chromosome": "13", "start_pos": 865348, "end_pos": 863245, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011726", "url": "https://www.ensembl.org/id/ENSGALG00010011726" } ] } } ], "crossref": [ { "id": "A0A8V0YCA1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858589", "url": "https://www.ncbi.nlm.nih.gov/gene/100858589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858589", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAIHPTE", "url": "https://omabrowser.org/oma/group/QAIHPTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCA1", "url": "https://www.orthodb.org/?gene=A0A8V0YCA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44019:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44019:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149021", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEEEPPAEPQLRDTPDDICLEAAANAIALHPARELLAAGDVDGDVYLYSYCCVQGENRQLWSSGHHLKSCRDVAFSRDGQRLLTVAKDKAVHVLAVEDGRLETRIAKAHGTALNCVLPVDQHLLATGDDNGELKVWDLRKGGAVLEARQHEEYISAMAVDGAGKILLTASGDGTMGVFNIKRRRFELLSEPQSGDLTSVVLLKRGKKVACGSSEGTIYLFNWNGFGATSDRFSLRAESVDCMVPITESIVCTGSLDGVIRAVNILPNRVLGCVGQHLGEPIEQLAVAPGGQLLASCAHDQKVKFWDISSLGSMVVDEYRKKKKRGGPLKALSSKAAGSGEDFFADLREEQEATAEAATGSDSDDSD", "length": 369, "header": "tr|A0A8V0YCA1-1|A0A8V0YCA1_CHICK Isoform 1 of WD repeat-containing protein 55 OS=Gallus gallus OX=9031 GN=WDR55 PE=3 SV=1 CANONICAL=A0A8V0YCA1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1/entry", "sequence": { "sequence": "MAAPEEEPPAEPQLRDTPDDICLEAAANAIALHPARELLAAGDVDGDVYLYSYCCVQGENRQLWSSGHHLKSCRDVAFSRDGQRLLTVAKDKAVHVLAVEDGRLETRIAKAHGTALNCVLPVDQHLLATGDDNGELKVWDLRKGGAVLEARQHEEYISAMAVDGAGKILLTASGDGTMGVFNIKRRRFELLSEPQSGDLTSVVLLKRGKKVACGSSEGTIYLFNWNGFGATSDRFSLRAESVDCMVPITESIVCTGSLDGVIRAVNILPNRVLGCVGQHLGEPIEQLAVAPGGQLLASCAHDQKVKFWDISSLGSMVVDEYRKKKKRGGPLKALSSKAAGSGEDFFADLREEQEATAEAATGSDSDDSD", "length": 369, "header": "tr|A0A8V0YCA1-1|A0A8V0YCA1_CHICK Isoform 1 of WD repeat-containing protein 55 OS=Gallus gallus OX=9031 GN=WDR55 PE=3 SV=1 CANONICAL=A0A8V0YCA1-1" }, "locus": { "chromosome": "13", "start_pos": 865077, "end_pos": 863281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028048.1", "url": "https://www.ensembl.org/id/ENSGALT00010028048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016092.1", "url": "https://www.ensembl.org/id/ENSGALP00010016092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RGE2-1", "protein_name": "WD repeat-containing protein 55", "gene_name": "WDR55", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRTCEEKPTDEVSDEEDPDSTEAPARIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFRYSCQEGDTKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHFLDVEQGRLERRISKAHGAPINSLLLVDENVLATGDDTGGVRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVTLMKCGKKVVCGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCAGSTDGVIRAVHILPNRVVGSVGQHAGEPVEKLALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRRRKKKGGPLRALSSKAWSPDDFFAGLREEGEDAAAPVQEEEESEDDSD", "length": 384 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O80775-1", "protein_name": "WD repeat-containing protein 55", "gene_name": "WDR55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEIDLGANAFGIDFHPSTNLVAAGLIDGHLHLYRYDSDSSLVRERKVRAHKESCRAVRFIDDGQRIVTASADCSILATDVETGAQVAHLENAHEDAVNTLINVTETTIASGDDKGCVKIWDTRQRSCSHEFNAHEDYISGMTFASDSMKLVVTSGDGTLSVCNLRTSKVQSQSEFSEDELLSVVIMKNGRKVICGTQNGTLLLYSWGFFKDCSDRFVDLAPNSVDALLKLDEDRLITGCDNGIISLVGILPNRIIQPIGSHDYPIEDLALSHDKKFLGSTAHDSMLKLWNLEEILEGSNVNSGNASGAAEDSDSDNDGMDLDNDPSKSSKGSKRKTKSKANTLNATNNFFADL", "length": 353 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q06214-1", "protein_name": "WD repeat-containing protein JIP5", "gene_name": "JIP5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKSKKKTDVVDSTNLPILELLSLKAPIFQSLLHPELPIIITGFGTGHIVCHRYDPAKLQSHLDRRRRIDTATTGKDAKKGVCPWIRLDIDLETGDLKFVDIEEQQQQKQTGKDEDLGVKTLWKTKRHKGSVRAMCFDSKGDNIFSVGSDNVLKKANTMTGKVVKKVNLSSLFNSEEKKNDKFTKLCASQTHPFILIGDESGNIHVINSENLALSNSIRSIHFGDSINDIFHFDKRSAYKFISLGQTTLAYFDVRDKDAKPNVAGNEDGKILISDDQEDEVLCGCFVDPEVADTLLCGMGEGIVTVWKPNKNDLEDQMSRIKISKDESIDCIVPTLQDDNCVWCGCSNGNIYKVNAKLGKVVEIRNHSELDEVSFVDLDFEYRVVSGGLENIKIWELSSDDVEENASVESDSDEPLSHSDEDLSDDTSSDDETTLVGLSKEELLDELDKDLKEDHQEEKESNSKSVKKRKIMKENNKKKDLYEHGIKKFDDL", "length": 492 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54SA5-1", "protein_name": "WD repeat-containing protein 55 homolog", "gene_name": "wdr55", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTSSEGDHELAPNDISFNTIPFSLNFHPTEDLLVVSDAEGRLKLFKYSLDENEVKLSLRPHQSGCRQANFSSDGKYIFTASSDCSMKVIDINTGSILYTREEAHDYPINCLVSKEFMVFTGDDEGTIKVWDMRQQNIVCEFQEHGDFISDITTIDDRHIAATSGDGGVSIYNFVRKSMDDISEKSDNELLSCLSLDNGQKLVCGSQDGSILIYDRNNLENVKKFAGHPQSVDALVKVNNNTFFSGSSDGIIRFIGLRPKKLLGVVGEHSTFPIERMAISRDNRYLGSISHDFSLKFWNVASFYEEDESEDADSANANANEIENDDDDDDDDDEIEDIENATKVDDDSGSEMGDDDDDDDDEEQEEEEESSSDEDIKRKKPQQNPIKAQQIEKQKQKQNQKRSFFKDL", "length": 408 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q58DT8-1", "protein_name": "WD repeat-containing protein 55", "gene_name": "WDR55", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRMCEERAAEDGSDEEDPDATEAPARIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHFLDVELGRLERRISKAHGAPINSLLLVDENVLATGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPDKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVTLMKYGRKVACGSSEGTIYLFNWDGFGATSDRFALRAESIDCMVPVTESLLCAGSTDGVIRAVNILPNRVVGSVGQHAEEPVENLALSHCGCFLASSGHDQRLKFWDMAQLRALVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREEGEDAKTLEEEESEDDSD", "length": 382 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CX97-1", "protein_name": "WD repeat-containing protein 55", "gene_name": "Wdr55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPTCEESPAEDSNNEEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHILDVEQGQLERRISKAHSAPINSVLLVDENALVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCIVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEALALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEDAKAPEEVVRESDDDDDDSD", "length": 388 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6Y2-1", "protein_name": "WD repeat-containing protein 55", "gene_name": "WDR55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRTCEERPAEDGSDEEDPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETKELWSSGHHLKACRAVAFSEDGQKLITVSKDKAIHVLDVEQGQLERRVSKAHGAPINSLLLVDENVLATGDDTGGICLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGIFNIKRRRFELLSEPQSGDLTSVTLMKWGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVEELALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRRRKKKGGPLRALSSKTWSTDDFFAGLREEGEDSMAQEEKEETGDDSD", "length": 383 }, "evidence": [ { "id": "A0A8V0YCA1", "url": "https://omabrowser.org/oma/group/A0A8V0YCA1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"header": "tr|A0A8V0YCB2-1|A0A8V0YCB2_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112533425 PE=4 SV=1 CANONICAL=A0A8V0YCB2-1" }, "locus": { "chromosome": "13", "start_pos": 1314603, "end_pos": 1311832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026835.1", "url": "https://www.ensembl.org/id/ENSGALT00010026835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015292.1", "url": "https://www.ensembl.org/id/ENSGALP00010015292.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCB2", 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"XP_040505985", "name": "poly(U)-specific endoribonuclease-A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505985" }, "gene_names": [ { "name": "ENDOUL", "type": "recommended", "evidence": [ { "id": "A0A8V0YCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" } ] }, { "name": "ENDOUL", "type": "synonym", "evidence": [ { "id": "XP_040505985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505985" } ] } ], "protein_names": [ { "name": "Uridylate-specific endoribonuclease", "type": "recommended", "evidence": [ { "id": "A0A8V0YCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6/entry#names_and_taxonomy" } ] }, { "name": "poly(U)-specific endoribonuclease-A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040505985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505985" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505985" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENDOUL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418221", "url": "https://www.ncbi.nlm.nih.gov/gene/418221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418221", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERNDGGW", "url": "https://omabrowser.org/oma/group/ERNDGGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCC6", "url": "https://www.orthodb.org/?gene=A0A8V0YCC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"A0A8V0YCC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6/entry", "sequence": { "sequence": "MADRKALNHELSKLFNEMWDMDVNRFTPGKDYAIELQGKADAVLQGDSVVQDSAARHLFHYVNEERLKNIKTFATFISLLDNYETSTGVEEIVTPEEIAENNCFLDAILMTGVMKVSHEFSFVTEDTELQIHISLFSILQLAHEYLLKKKLAKPNLADFKYQLYDIWFQLYPRKEGDRPDSCGFEHVFVGETRRGKQILGLHNWVQFYLQEKHKQIDYKGYIARKNKTRPDRDDQVLSIQFSWKGSVKPIGSTFIGVSPEFEFALYTVIFLLSEERVTRKTVKIEEYELQIVVCRHGRHIGTAYPVLLNTSNED", "length": 314, "header": "tr|A0A8V0YCC6-1|A0A8V0YCC6_CHICK Isoform 1 of Uridylate-specific endoribonuclease OS=Gallus gallus OX=9031 GN=ENDOUL PE=1 SV=1 CANONICAL=A0A8V0YCC6-1" }, "locus": { "chromosome": "1", "start_pos": 68407780, "end_pos": 68398771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031579.1", "url": "https://www.ensembl.org/id/ENSGALT00010031579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018450.1", "url": "https://www.ensembl.org/id/ENSGALP00010018450.1" } ] } }, { "isoform_ac": "A0A8V0YKR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR0/entry", "sequence": { "sequence": "MADRKALNHELSKLFNEMWDMDVNRFTPGKDYAIELQGKADAVLQGDSVVQDSAARHLFHYVNEERLKNIKTFATFISLLDNYETSTGVEEIVTPEEIAENNCFLDAILMTGVMKLAHEYLLKKKLAKPNLADFKYQLYDIWFQLYPRKEGDRPDSCGFEHVFVGETRRGKQILGLHNWVQFYLQEKHKQIDYKGYIARKNKTRPDRDDQVLSIQFSWKGSVKPIGSTFIGVSPEFEFALYTVIFLLSEERVTRKTVKIEEYELQIVVCRHGRHIGTAYPVLLNTSNED", "length": 289, "header": "tr|A0A8V0YKR0-1|A0A8V0YKR0_CHICK Computationally mapped isoform of Uridylate-specific endoribonuclease OS=Gallus gallus OX=9031 GN=ENDOUL PE=1 SV=1 CANONICAL=A0A8V0YCC6-1" }, "locus": { "chromosome": "1", "start_pos": 68407780, "end_pos": 68398771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031583.1", "url": "https://www.ensembl.org/id/ENSGALT00010031583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018453.1", "url": "https://www.ensembl.org/id/ENSGALP00010018453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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"pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67792", "name": "", "equation": "ribonucleotidyl-uridine-RNA = a 5'-end dephospho-uridine-RNA + a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZSQ1-1", "A0A8V0YCC6-1" ], "evidence": [ { "id": "67792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67792" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YCC6", "gene_name": "ENDOUL", "activity": [ { "ec_number": "4.6.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZSQ1", "gene_name": "ENDOU", "activity": [ { "ec_number": "4.6.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZSQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC6" }, { "id": "PS51959", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51959" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EndoU", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 309, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 309, "end_pos": 311 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCD3-1", "uniprot_ac": "A0A8V0YCD3", "uniprot_id": "A0A8V0YCD3_CHICK", "mass": { "chemical_mass": 48745.0, "monoisotopic_mass": 48745.0 }, "refseq": { "ac": "XP_424990", "name": "cyclic AMP-responsive element-binding protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424990" }, "gene_names": [ { "name": "CREB3L4", "type": "recommended", "evidence": [ { "id": "A0A8V0YCD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3" } ] }, { "name": "CREB3L4", "type": "synonym", "evidence": [ { "id": "XP_424990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424990" } ] } ], "protein_names": [ { "name": "cAMP responsive element binding protein 3 like 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YCD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3/entry#names_and_taxonomy" } ] }, { "name": "cyclic AMP-responsive element-binding protein 3", "type": "synonym", "evidence": [ { "id": "XP_424990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424990" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424990" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CREB3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427417", "url": "https://www.ncbi.nlm.nih.gov/gene/427417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427417", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHRTDEM", "url": "https://omabrowser.org/oma/group/QHRTDEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCD3", "url": "https://www.orthodb.org/?gene=A0A8V0YCD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8874211", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8874211", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPEPLAALPDGDLLDFLLNDDAPAAGSPAGDGPLLGDWVLPELELLDKEMDSFISSLLSPSEDEPCLLQGCLPADSDSSTSEDQNPFHSSGSDVASSPQSSDIVQFDHNYSLHQDWPALESVRSDMAEGDVSIDLETWMCLEGTNETLQESCSFPVTVAVDAGPQLMPGAPMQSNFPELVLTEEERQLLEKDGVSLPTCLPLTKAEERLLKKVRRKIRNKQSAQDSRRRKKIYVDGLENRVAACTAQNHELQKKVQLLQKQNMSLLEQLRKLQALVRQSTTKTTTASTCIMVLVLSFCLILSPSLYSFGSRGPQPEFRVLSRQIREFPNKVWQAAPAVQEEVVLERLSPEPEDTSLGSLNQSREEGQSPPKPDPRSAFNGNSSSDPPAGSELGHPQPQEQQSRRDALHSEVLAPWKDENQEWVERTTSVVIQQHRTDEM", "length": 441, "header": "tr|A0A8V0YCD3-1|A0A8V0YCD3_CHICK Isoform 1 of cAMP responsive element binding protein 3 like 4 OS=Gallus gallus OX=9031 GN=CREB3L4 PE=3 SV=1 CANONICAL=A0A8V0YCD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD3/entry", "sequence": { "sequence": "MAGPEPLAALPDGDLLDFLLNDDAPAAGSPAGDGPLLGDWVLPELELLDKEMDSFISSLLSPSEDEPCLLQGCLPADSDSSTSEDQNPFHSSGSDVASSPQSSDIVQFDHNYSLHQDWPALESVRSDMAEGDVSIDLETWMCLEGTNETLQESCSFPVTVAVDAGPQLMPGAPMQSNFPELVLTEEERQLLEKDGVSLPTCLPLTKAEERLLKKVRRKIRNKQSAQDSRRRKKIYVDGLENRVAACTAQNHELQKKVQLLQKQNMSLLEQLRKLQALVRQSTTKTTTASTCIMVLVLSFCLILSPSLYSFGSRGPQPEFRVLSRQIREFPNKVWQAAPAVQEEVVLERLSPEPEDTSLGSLNQSREEGQSPPKPDPRSAFNGNSSSDPPAGSELGHPQPQEQQSRRDALHSEVLAPWKDENQEWVERTTSVVIQQHRTDEM", "length": 441, "header": "tr|A0A8V0YCD3-1|A0A8V0YCD3_CHICK Isoform 1 of cAMP responsive element binding protein 3 like 4 OS=Gallus gallus OX=9031 GN=CREB3L4 PE=3 SV=1 CANONICAL=A0A8V0YCD3-1" }, "locus": { "chromosome": "Z", "start_pos": 9725192, "end_pos": 9721592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028127.1", "url": "https://www.ensembl.org/id/ENSGALT00010028127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016130.1", "url": "https://www.ensembl.org/id/ENSGALP00010016130.1" } ] } } ], 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"MPEHLPLEPPGSASGFPLPEGRANTGSLHKWLHVQPLEKNETGDIEMELSAAETASAADPEELIETSGSASTDPTGHNQAPAGHAAGTSIQEEQDSQMFPEEEETKGLPSSSSEESAGLASVFSCLSFPQKLWVLVESDQVKSIQWGHGGNCIVIQEEMFKVEVLAREAPARAFESTCMKSFVRQLNLYGFTKVPQHLERSFLPQFLAEGEAFSAHRKLLLYSSPHFRKDYPQLLGHCKRRVAHKRRPMAAPVPVPAPALQEALNKNPQKSSPNGQPTQGVAAGPVRGLQAAEPQGTQAAAPMGPPPAKSPKNDTLRAQGGNVHILPGPAAATAPEHCQVLPCSMLPPSSSQTLVATCVPPSQGTLPFLLPSFTPGCPQQELLQPPETPQLQAPWAALTFLDSCFAMAMRAAAMMMPPDWQPHAIPHCPTCTCSRHQADAGHGTAP", "length": 446, "header": "tr|A0A8V0YCE1-1|A0A8V0YCE1_CHICK Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Gallus gallus OX=9031 GN=HSFX2 PE=3 SV=1 CANONICAL=A0A8V0YCE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE1/entry", "sequence": { "sequence": "MPEHLPLEPPGSASGFPLPEGRANTGSLHKWLHVQPLEKNETGDIEMELSAAETASAADPEELIETSGSASTDPTGHNQAPAGHAAGTSIQEEQDSQMFPEEEETKGLPSSSSEESAGLASVFSCLSFPQKLWVLVESDQVKSIQWGHGGNCIVIQEEMFKVEVLAREAPARAFESTCMKSFVRQLNLYGFTKVPQHLERSFLPQFLAEGEAFSAHRKLLLYSSPHFRKDYPQLLGHCKRRVAHKRRPMAAPVPVPAPALQEALNKNPQKSSPNGQPTQGVAAGPVRGLQAAEPQGTQAAAPMGPPPAKSPKNDTLRAQGGNVHILPGPAAATAPEHCQVLPCSMLPPSSSQTLVATCVPPSQGTLPFLLPSFTPGCPQQELLQPPETPQLQAPWAALTFLDSCFAMAMRAAAMMMPPDWQPHAIPHCPTCTCSRHQADAGHGTAP", "length": 446, "header": "tr|A0A8V0YCE1-1|A0A8V0YCE1_CHICK Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Gallus gallus OX=9031 GN=HSFX2 PE=3 SV=1 CANONICAL=A0A8V0YCE1-1" }, "locus": { "chromosome": "1", "start_pos": 68417084, "end_pos": 68414960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031597.1", "url": "https://www.ensembl.org/id/ENSGALT00010031597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018465.1", "url": "https://www.ensembl.org/id/ENSGALP00010018465.1" } ] } } ], 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"gene_name": "HSFX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDKRSLSMARCEERNSRGQDHGLERVPFPPQLQSETYLHPADPSPAWDDPGSTGSPNLRLLTEEIAFQPLAEEASFRRPHPDGDVPPQGEDNLLSLPFPQKLWRLVSSNQFSSIWWDDSGACRVINQKLFEKEILKRDVAHKVFATTSIKSFFRQLNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRVGVKSAPRHQEEDKPEAAGSCLAPADTEQQDHTSPNENDQVTPQHREPAGPNTQIRSGSAPPATPVMVPDSAVASDNSPVTQPAGEWSEGSQAHVTPVAAVPGPAALPFLYVPGSPTQMNSYGPVVALPTASRSTLAMDTTGLPAPGMLPFCHLWVPVTLVAAGAAQPAASMVMFPHLPALHHHCPHSHRTSQYMPASDGPQAYPDYADQST", "length": 423 }, "evidence": [ { "id": "A0A8V0YCE1", "url": "https://omabrowser.org/oma/group/A0A8V0YCE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE1", "url": 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"end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE1" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 241, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YDQ3-1", "uniprot_ac": "A0A8V0YDQ3", "uniprot_id": "A0A8V0YDQ3_CHICK", "mass": { "chemical_mass": 64200.0, "monoisotopic_mass": 64200.0 }, "refseq": { "ac": "NP_990190", "name": "interferon alpha/beta receptor 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" }, "gene_names": [ { "name": "IFNAR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YDQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ] }, { "name": "IFNAR1", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] } ], "protein_names": [ { "name": "Interferon alpha and beta receptor subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YDQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3/entry#names_and_taxonomy" } ] }, { "name": "interferon (alpha, beta and omega) receptor 1", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] }, { "name": "interferon alpha/beta receptor 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] }, { "name": "interferon alpha/beta receptor 1", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] }, { "name": "interferon receptor", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] }, { "name": "soluble receptor", "type": "synonym", "evidence": [ { "id": "NP_990190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF082664.1, SRR13267655.193321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000020.1. On Sep 23, 2021 this sequence version replaced NP_990190.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFNAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3", "locus": { "chromosome": "1", "start_pos": 105384094, "end_pos": 105365280, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012049", "url": "https://www.ensembl.org/id/ENSGALG00010012049" } ] } } ], "crossref": [ { "id": "A0A8V0YDQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395665", "url": "https://www.ncbi.nlm.nih.gov/gene/395665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395665", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCINTTV", "url": "https://omabrowser.org/oma/group/YCINTTV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCF5", "url": "https://www.orthodb.org/?gene=A0A8V0YCF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDQ3", "url": "https://www.orthodb.org/?gene=A0A8V0YDQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-909733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912694", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAACASGRLAAVLLCVLVVVSRCCAGQTNLKSPQDIQVYAVNTNFTLMWNYTGDGTNVTFSAQYQCFDDLQTSEPEWKELSGCQNVSHTECDFSSAITAYYDTHHIRIRAERREAKSPWSSIFEMIPYEIAQIGPPEIALQSINGAIKINISPPEANQVRKMWLISVFFKYNVVIWDNSSNVEKVRSILPIDVINDLAPETTYCLKVQATVPLEYKEGLFSPIHCIKTTRKVNDLLCPTNVRVFALNMKFYLLWDNHYNEHVTYTVQYLTGYLKNLYDDYSSKWQKVSGCENITSMKCNLSSVIKPTSASYYFRVQAMNEYNKSCLSKDVEVDPPVTNEIGPPDVKVDISDVLLHIKITPPGGPGNKIMSDLYDFSYQILYWKNSSDNEEEVKMKETKQTIATVSDLAPSTLYCVKVQAFSEAYNKSSDFSREECIGTAGGKHLPLIILATFAGALTVVLIVASLVIFFLYQVYNKIKYMFFPSCQTPLNIEGFGAQLFNSPFVPTVEEPVEICYIIESRITEEVNQIDFKDNKHFKQSSRDSGNYSYDDNTSQSKGSEETLGNDIL", "length": 569, "header": "tr|A0A8V0YDQ3-1|A0A8V0YDQ3_CHICK Isoform 1 of Interferon alpha and beta receptor subunit 1 OS=Gallus gallus OX=9031 GN=IFNAR1 PE=4 SV=1 CANONICAL=A0A8V0YDQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF5/entry", "sequence": { "sequence": "LLSWTALFLDILTILICLDIVFFIGQTNLKSPQDIQVYAVNTNFTLMWNYTGDGTNVTFSAQYQCFDDLQTSEPEWKELSGCQNVSHTECDFSSAITAYYDTHHIRIRAERREAKSPWSSIFEMIPYEIAQIGPPEIALQSINGAIKINISPPEANQVRKMWLISVFFKYNVVIWDNSSNVEKVRSILPIDVINDLAPETTYCLKVQATVPLEYKEGLFSPIHCIKTTRKVNDLLCPTNVRVFALNMKFYLLWDNHYNEHVTYTVQYLTGYLKNLYDDYSSKWQKVSGCENITSMKCNLSSVIKPTSASYYFRVQAMNEYNKSCLSKDVEVDPPVTNEIGPPDVKVDISDVLLHIKITPPGGPGNKIMSDLYDFSYQILYWKNSSDNEEEVKMKETKQTIATVSDLAPSTLYCVKVQAFSEAYNKSSDFSREECIGTAGGKHLPLIILATFAGALTVVLIVASLVIFFLYQVYNKIKYMFFPSCQTPLNIEGFGAQLFNSPFVPTVEEPVEICYIIESRITEEVNQIDFKDNKHFKQSSRDSGNYSYDDNTSQSKGSEETLGNDIL", "length": 566, "header": "tr|A0A8V0YCF5-1|A0A8V0YDQ3_CHICK Computationally mapped isoform of Interferon alpha and beta receptor subunit 1 OS=Gallus gallus OX=9031 GN=IFNAR1 PE=4 SV=1 CANONICAL=A0A8V0YDQ3-1" }, "locus": { "chromosome": "1", "start_pos": 105382743, "end_pos": 105370047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028866.1", "url": "https://www.ensembl.org/id/ENSGALT00010028866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016625.1", "url": "https://www.ensembl.org/id/ENSGALP00010016625.1" } ] } }, { "isoform_ac": "A0A8V0YDQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3/entry", "sequence": { "sequence": "MAEAACASGRLAAVLLCVLVVVSRCCAGQTNLKSPQDIQVYAVNTNFTLMWNYTGDGTNVTFSAQYQCFDDLQTSEPEWKELSGCQNVSHTECDFSSAITAYYDTHHIRIRAERREAKSPWSSIFEMIPYEIAQIGPPEIALQSINGAIKINISPPEANQVRKMWLISVFFKYNVVIWDNSSNVEKVRSILPIDVINDLAPETTYCLKVQATVPLEYKEGLFSPIHCIKTTRKVNDLLCPTNVRVFALNMKFYLLWDNHYNEHVTYTVQYLTGYLKNLYDDYSSKWQKVSGCENITSMKCNLSSVIKPTSASYYFRVQAMNEYNKSCLSKDVEVDPPVTNEIGPPDVKVDISDVLLHIKITPPGGPGNKIMSDLYDFSYQILYWKNSSDNEEEVKMKETKQTIATVSDLAPSTLYCVKVQAFSEAYNKSSDFSREECIGTAGGKHLPLIILATFAGALTVVLIVASLVIFFLYQVYNKIKYMFFPSCQTPLNIEGFGAQLFNSPFVPTVEEPVEICYIIESRITEEVNQIDFKDNKHFKQSSRDSGNYSYDDNTSQSKGSEETLGNDIL", "length": 569, "header": "tr|A0A8V0YDQ3-1|A0A8V0YDQ3_CHICK Isoform 1 of Interferon alpha and beta receptor subunit 1 OS=Gallus gallus OX=9031 GN=IFNAR1 PE=4 SV=1 CANONICAL=A0A8V0YDQ3-1" }, "locus": { "chromosome": "1", "start_pos": 105382743, "end_pos": 105365378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028869.1", "url": "https://www.ensembl.org/id/ENSGALT00010028869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016628.1", "url": "https://www.ensembl.org/id/ENSGALP00010016628.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395665", "resource": "KEGG Pathway" }, { "id": "R-GGA-909733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909733", "resource": "Reactome", "description": "Interferon alpha/beta signaling" }, { "id": "R-GGA-912694", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "resource": "Reactome", "description": "Regulation of IFNA/IFNB signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZDS9-1", "protein_name": "Interferon alpha/beta receptor 1", "gene_name": "Ifnar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAVVGAAALVLVAGAPWMLPVASGEPRALSEGRAAGRESWKRVNGVHAGSPRRPPARSSLRTLTRARALGRLEGEDNLRPPEDVAIYIIDDNYTLKWNHHRESMGNVTFSAEYQKGEGRIWLKVPKCQHITRTKCEFSLLGINVYSKTQFRVRAEEGNSTSSWNEADSFIPFYKAHVSPPRVHLKAEDKAILVYISPPGEDGTMWAQEKRCFNYTIRIWGRSFPVREIKPMYFPKKISKLLPETTYCLEVRAVHTSLQRHSNYSSARCINTTVANKIPVPENLEVDVQGDSYVLKWDHAFANMTFKAQWIPVYSKSSPGNHSDKWKPIPTCANVQTTHCVSPRETFHTGTFFLRVQASDGNNTSFWSEEKLIDSQKYTLLPPPVIAVTPTGDSLLVYVSCKDSKCNGLIYEVIFWENTSNTEKRQHPQSMIKEHPEFNVVNLRPLTVYCVQARVLSTGVWNKTSKFSDKLCKKTHPGNSSVTWIITGFGALLFSAMAFYAGRSLQKYLYYVFSPPLKPPCSIDEFFSELPSKSLLLLTAEEHTERCFVIENTGVVAGEENRAPEEELRKYSSQSSQDSGNYSNEEEESVGPESGQDMLSTAPSGSPWSLPCPAGTLEDGACFPGKEKHLQSPVLRTQPALHG", "length": 643 }, "evidence": [ { "id": "A0A8V0YDQ3", "url": "https://omabrowser.org/oma/group/A0A8V0YDQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P17181-1", "protein_name": "Interferon alpha/beta receptor 1", "gene_name": "IFNAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV", "length": 557 }, "evidence": [ { "id": "A0A8V0YDQ3", "url": "https://omabrowser.org/oma/group/A0A8V0YDQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P33896-1", "protein_name": "Interferon alpha/beta receptor 1", "gene_name": "Ifnar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAVVGAAALVLVAGAPWVLPSAAGGENLKPPENIDVYIIDDNYTLKWSSHGESMGSVTFSAEYRTKDEAKWLKVPECQHTTTTKCEFSLLDTNVYIKTQFRVRAEEGNSTSSWNEVDPFIPFYTAHMSPPEVRLEAEDKAILVHISPPGQDGNMWALEKPSFSYTIRIWQKSSSDKKTINSTYYVEKIPELLPETTYCLEVKAIHPSLKKHSNYSTVQCISTTVANKMPVPGNLQVDAQGKSYVLKWDYIASADVLFRAQWLPGYSKSSSGSRSDKWKPIPTCANVQTTHCVFSQDTVYTGTFFLHVQASEGNHTSFWSEEKFIDSQKHILPPPPVITVTAMSDTLLVYVNCQDSTCDGLNYEIIFWENTSNTKISMEKDGPEFTLKNLQPLTVYCVQARVLFRALLNKTSNFSEKLCEKTRPGSFSTIWIITGLGVVFFSVMVLYALRSVWKYLCHVCFPPLKPPRSIDEFFSEPPSKNLVLLTAEEHTERCFIIENTDTVAVEVKHAPEEDLRKYSSQTSQDSGNYSNEEEESVGTESGQAVLSKAPCGGPCSVPSPPGTLEDGTCFLGNEKYLQSPALRTEPALLC", "length": 590 }, "evidence": [ { "id": "A0A8V0YDQ3", "url": "https://omabrowser.org/oma/group/A0A8V0YDQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q04790-1", "protein_name": "Interferon alpha/beta receptor 1", "gene_name": "IFNAR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLALLGATTLMLVAGRWVLPAASGEANLKPENVEIHIIDDNFFLKWNSSSESVKNVTFSADYQILGTDNWKKLSGCQHITSTKCNFSSVELENVFEKIELRIRAEEGNNTSTWYEVEPFVPFLEAQIGPPDVHLEAEDKAIILSISPPGTKDSIMWAMDRSSFRYSVVIWKNSSSLEERTETVYPEDKIYKLSPEITYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENIQINADNQIYVLKWDYPYENATFQAQWLRAFFKKIPGNHSDKWKQIPNCENVTSTHCVFPREVSSRGIYYVRVRASNGNGTSFWSEEKEFNTEMKTIIFPPVISVKSVTDDSLHVSVGASEESENMSVNQLYPLIYEVIFWENTSNAERKVLEKRTNFIFPDLKPLTVYCVKARALIENDRRNKGSSFSDTVCEKTKPGNTSKTWLIVGTCTALFSIPVVIYVVSVFLRCVKYVFFPSSKPPSSVDEYFSDQPLRNLLLSTSEEQTERCFIIENASIITEIEETDEIDEVHKKYSSQTSQDSGNYSNEDENSGSKISEEFPQQDSV", "length": 560 }, "evidence": [ { "id": "A0A8V0YDQ3", "url": "https://omabrowser.org/oma/group/A0A8V0YDQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "type I interferon-mediated signaling pathway", "id": "GO:0060337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060337", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "pmid": "" }, { "name": "cellular response to interferon-beta", "id": "GO:0035458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "pmid": "" }, { "name": "positive regulation of cellular respiration", "id": "GO:1901857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via 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"https://www.uniprot.org/uniprotkb/A0A8V0YDQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YDQ8-1", "uniprot_ac": "A0A8V0YDQ8", "uniprot_id": "A0A8V0YDQ8_CHICK", "mass": { "chemical_mass": 138624.0, "monoisotopic_mass": 138624.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Myosin motor domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8", "locus": {} } ], "crossref": [ { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVFQQRSSNGSPPMEVLQCGSSSGGLPMWVLQQRSSKGGPPMEVLQRKSSNGSPPTEVLQRRSSNAGPPMEVLQCGSSSGGPPVEVLQRRSSNGSPPMWVFEWRSSSGSPPTEVLQCGSSKGGPPMWVLQWRTSNRGPPMWVLQRRSSNGSPPTEVLQRRSSSGGPPKEVLQWKSSNGGPPMWVLQWRTSNRGPPVWVLQCGSSNGGLPMWVLQWKSSKGGPPMEVLQCGSSHGGPPVWVLQCGSSNGGPPTEVLQWRSSNGGPPTEVLQRRSSNGGPPMEVLQGSPPTEVLQWRSSNGGPPMEVLQRRSSNGGPPMWVLQWRSSNGSPPTEVLQRKSSNGGPPVEVLQWKSSKGGPPLWVLQWRSSNGSPPTVVLQCGSSKGGPPMEVLQCGSSKEVLQRWSSNGSPPKEVLQRRSSNVGPPKEVLQRRSSNVSLPAEVLQWKSSNRGPPKEVLQCGSSNVGPPMEVLQWKSSNGGPPMEVLQWKSSNGSPPTEVLQWKSSNGGLPTEVLQCGSSNGSLPTEVLQWKSSNVGPPIEVFQWRSSNRGPPKEVLQWKSSNGSPPMWVLQWKSSNGGPPMWVLQCGSSNGSPPTEVLQWKSSSGGPPKEVLQCGSSNGGPPMEVLQRKSSNGSPPMEVLQRRSSKGSPPKEVLQRISSNGSPPVWVLQRRSSIVGPPMWVLQRRSSNAGPPMEVLQWKSSNGGPPMWVLQGSPPTEVLQRKSSKGGPPKEVLQCGSSKGSPPTEVLQCESSSGGPPMEVLQQRSSKGGPPVWVLQCGSSKGGPPKEVLQRRSSNGSPPTEVLQWKSSNGSPPTEVLRFGSSKGGLPTEVLQRKSSNGGPPKEVLQCGSSNGGLPTEVLQWKSSNGSPPMEVLQRKSSNVGPPTEVLQRRSSNVGPPTEVLQWRSSNVGPPMEVLQRRSSNGSPPMWVLQWRSSNGGPPTEVLQRRSSNGSPPTEVLQCGSSNGSPPTEILQRKSSNGGPPMEVLQRRSSNGSPPMEVLQRRSSNGGPPMEVLQWRFSNGGPPVWVLQWKSSKGGPPTEVLQWKSSNGGPPTEVLQRRSSNVGPPKEVLQRRSSNVSLPAEVLQWKSSNRGPPKEVLQWRSSNGSPPMEVLQYGSSKGGLLMWVLQRKSSNVGPPMEVFQCGSSNGGLPKEVLQRKSSSGGPPTEVLQQRSSKGGPPMEVLQRKSSNVGPPMEVLQRRSSNGSPPTEILQRKSSNGGPPKEVLQCGSSNGSPPTEVLQRRSPFGMGSLMGFWGSLPPQFRGSLQLLMETLNATTPHYVRCIKPNEEREPFR", "length": 1289, "header": "tr|A0A8V0YDQ8-1|A0A8V0YDQ8_CHICK Isoform 1 of Myosin motor domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YDQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF9/entry", "sequence": { "sequence": "MEVLQRRSSSVGPPMEVFQCGSSKGGPPTEVLQCGSSNGSPPTEVLQQRSSNGSPPTEVLQCGSSNGGLPTEVLQRKSSNGSPPMWVLQRRSSNVGPPTEVLQRRSSNGSPPTEVFQWKSSNGSPPAEVLQRGSSNGSPPMWVFEWRSSSGSPPTEVLQCGSSKGGPPMWVLQWRTSNRGPPVWVLQCGSSNGGLPMWVLQWKSSKGGPPMEVLQCGSSHGGPPVWVLQCGSSNGGPPTEVLQWRSSNGGPPTEVLQRRSSNGGPPMEVLQGSPPTEVLQWRSSNGGPPMEVLQRRSSNGGPPMWVLQWRSSNGSPPTEVLQRKSSNGGPPVEVLQWKSSKGGPPLWVLQWRSSNGSPPTVVLQCGSSKGGPPMEVLQCGSSKEVLQRWSSNGSPPKEVLQRRSSNVGPPKEVLQRRSSNVSLPAEVLQWKSSNRGPPKEVLQCGSSNVGPPMEVLQWKSSNGGPPMEVLQWKSSNGSPPTEVLQWKSSNGGLPTEVLQCGSSNGSLPTEVLQWKSSNVGPPIEVFQWRSSNRGPPKEVLQWKSSNGSPPMWVLQWKSSNGGPPMWVLQCGSSNGSPPTEVLQWKSSSGGPPKEVLQCGSSNGGPPMEVLQRKSSNGSPPMEVLQRRSSKGSPPKEVLQRISSNGSPPVWVLQRRSSIVGPPMWVLQRRSSNAGPPMEVLQWKSSNGGPPMWVLQGSPPTEVLQRKSSKGGPPKEVLQCGSSKGSPPTEVLQCESSSGGPPMEVLQQRSSKGGPPVWVLQCGSSKGGPPKEVLQRRSSNGSPPTEVLQWKSSNGSPPTEVLRFGSSKGGLPTEVLQRKSSNGGPPKEVLQCGSSNGGLPTEVLQWKSSNGSPPMEVLQRKSSNVGPPTEVLQRRSSNVGPPTEVLQWRSSNVGPPMEVLQRRSSNGSPPMWVLQWRSSNGGPPTEVLQRRSSNGSPPTEVLQRRSSNVGPPTEVLQRRSSSGGPRLGWGP", "length": 970, "header": "tr|A0A8V0YCF9-1|A0A8V0YDQ8_CHICK Computationally mapped isoform of Myosin motor domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YDQ8-1" }, "locus": { "chromosome": "W", "start_pos": 337756, "end_pos": 333573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028871.1", "url": "https://www.ensembl.org/id/ENSGALT00010028871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016630.1", "url": "https://www.ensembl.org/id/ENSGALP00010016630.1" } ] } }, { "isoform_ac": "A0A8V0YDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8/entry", "sequence": { "sequence": "MEVFQQRSSNGSPPMEVLQCGSSSGGLPMWVLQQRSSKGGPPMEVLQRKSSNGSPPTEVLQRRSSNAGPPMEVLQCGSSSGGPPVEVLQRRSSNGSPPMWVFEWRSSSGSPPTEVLQCGSSKGGPPMWVLQWRTSNRGPPMWVLQRRSSNGSPPTEVLQRRSSSGGPPKEVLQWKSSNGGPPMWVLQWRTSNRGPPVWVLQCGSSNGGLPMWVLQWKSSKGGPPMEVLQCGSSHGGPPVWVLQCGSSNGGPPTEVLQWRSSNGGPPTEVLQRRSSNGGPPMEVLQGSPPTEVLQWRSSNGGPPMEVLQRRSSNGGPPMWVLQWRSSNGSPPTEVLQRKSSNGGPPVEVLQWKSSKGGPPLWVLQWRSSNGSPPTVVLQCGSSKGGPPMEVLQCGSSKEVLQRWSSNGSPPKEVLQRRSSNVGPPKEVLQRRSSNVSLPAEVLQWKSSNRGPPKEVLQCGSSNVGPPMEVLQWKSSNGGPPMEVLQWKSSNGSPPTEVLQWKSSNGGLPTEVLQCGSSNGSLPTEVLQWKSSNVGPPIEVFQWRSSNRGPPKEVLQWKSSNGSPPMWVLQWKSSNGGPPMWVLQCGSSNGSPPTEVLQWKSSSGGPPKEVLQCGSSNGGPPMEVLQRKSSNGSPPMEVLQRRSSKGSPPKEVLQRISSNGSPPVWVLQRRSSIVGPPMWVLQRRSSNAGPPMEVLQWKSSNGGPPMWVLQGSPPTEVLQRKSSKGGPPKEVLQCGSSKGSPPTEVLQCESSSGGPPMEVLQQRSSKGGPPVWVLQCGSSKGGPPKEVLQRRSSNGSPPTEVLQWKSSNGSPPTEVLRFGSSKGGLPTEVLQRKSSNGGPPKEVLQCGSSNGGLPTEVLQWKSSNGSPPMEVLQRKSSNVGPPTEVLQRRSSNVGPPTEVLQWRSSNVGPPMEVLQRRSSNGSPPMWVLQWRSSNGGPPTEVLQRRSSNGSPPTEVLQCGSSNGSPPTEILQRKSSNGGPPMEVLQRRSSNGSPPMEVLQRRSSNGGPPMEVLQWRFSNGGPPVWVLQWKSSKGGPPTEVLQWKSSNGGPPTEVLQRRSSNVGPPKEVLQRRSSNVSLPAEVLQWKSSNRGPPKEVLQWRSSNGSPPMEVLQYGSSKGGLLMWVLQRKSSNVGPPMEVFQCGSSNGGLPKEVLQRKSSSGGPPTEVLQQRSSKGGPPMEVLQRKSSNVGPPMEVLQRRSSNGSPPTEILQRKSSNGGPPKEVLQCGSSNGSPPTEVLQRRSPFGMGSLMGFWGSLPPQFRGSLQLLMETLNATTPHYVRCIKPNEEREPFR", "length": 1289, "header": "tr|A0A8V0YDQ8-1|A0A8V0YDQ8_CHICK Isoform 1 of Myosin motor domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YDQ8-1" }, "locus": { "chromosome": "W", "start_pos": 337560, "end_pos": 333442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028874.1", "url": "https://www.ensembl.org/id/ENSGALT00010028874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016633.1", "url": "https://www.ensembl.org/id/ENSGALP00010016633.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ8" } ], "pmid": "" }, { 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCMF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YDR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770239", "url": "https://www.ncbi.nlm.nih.gov/gene/770239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRHEGVSCDACLKGNFRGRRFKCLICYDYDLCATCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGHTETTLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLISFSEMMQSLDFFFGGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSPGGLSSSQSSYSPSNREAMDPIAELLSQLSGVRRSAGGQINSSSPSASQLQQLQMQLQLERQHAQAARQQLETARNATRRTNTINVNTTITQSATTTNTSNTENSQQTIQNSQFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLMQEESSSSDEDERGEIADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL", "length": 392, "header": "tr|A0A8V0YDR9-1|A0A8V0YDR9_CHICK Isoform 1 of E3 ubiquitin-protein ligase KCMF1 OS=Gallus gallus OX=9031 GN=KCMF1 PE=1 SV=1 CANONICAL=A0A8V0YDR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH2/entry", "sequence": { "sequence": "MIIYGVSCDACLKGNFRGRRFKCLICYDYDLCATCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGHTETTLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLYDESSGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSPGGLSSSQSSYSPSNREAMDPIAELLSQLSGVRRSAGGQINSSSPSASQLQQLQMQLQLERQHAQAARQQLETARNATRRTNTINVNTTITQSATTTNTSNTENSQQTIQNSQFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLMQEESSSSDEDERGEIADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL", "length": 381, "header": "tr|A0A8V0YCH2-1|A0A8V0YDR9_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase KCMF1 OS=Gallus gallus OX=9031 GN=KCMF1 PE=1 SV=1 CANONICAL=A0A8V0YDR9-1" }, "locus": { "chromosome": "Z", "start_pos": 54493465, "end_pos": 54464580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028881.1", "url": "https://www.ensembl.org/id/ENSGALT00010028881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016640.1", "url": "https://www.ensembl.org/id/ENSGALP00010016640.1" } ] } }, { "isoform_ac": "A0A8V0YDR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9/entry", "sequence": { "sequence": "MSRHEGVSCDACLKGNFRGRRFKCLICYDYDLCATCYESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGHTETTLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLISFSEMMQSLDFFFGGVRHVRRMFHPGRGLGGPRARRSNMHFTSSSPGGLSSSQSSYSPSNREAMDPIAELLSQLSGVRRSAGGQINSSSPSASQLQQLQMQLQLERQHAQAARQQLETARNATRRTNTINVNTTITQSATTTNTSNTENSQQTIQNSQFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLMQEESSSSDEDERGEIADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL", "length": 392, "header": "tr|A0A8V0YDR9-1|A0A8V0YDR9_CHICK Isoform 1 of E3 ubiquitin-protein ligase KCMF1 OS=Gallus gallus OX=9031 GN=KCMF1 PE=1 SV=1 CANONICAL=A0A8V0YDR9-1" }, "locus": { "chromosome": "Z", "start_pos": 54517649, "end_pos": 54464580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028884.1", "url": "https://www.ensembl.org/id/ENSGALT00010028884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016643.1", "url": "https://www.ensembl.org/id/ENSGALP00010016643.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { 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This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046766679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046766679" } ] }, { "annotation": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCS7-1", "uniprot_ac": "A0A8V0YCS7", "uniprot_id": "A0A8V0YCS7_CHICK", "mass": { "chemical_mass": 88178.0, "monoisotopic_mass": 88178.0 }, "refseq": { "ac": "XP_015138454", "name": "E3 ubiquitin-protein ligase RNF19A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138454" }, "gene_names": [ { "name": "RNF19A", "type": "recommended", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "name": "RNF19A", "type": "synonym", "evidence": [ { "id": "XP_015138454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138454" } ] } ], "protein_names": [ { "name": "RBR-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.31", "type": "synonym", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF19A", "type": "synonym", "evidence": [ { "id": "XP_015138454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138454" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF19A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7", "locus": { "chromosome": "2", "start_pos": 128021731, "end_pos": 128080280, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011359", "url": "https://www.ensembl.org/id/ENSGALG00010011359" } ] } } ], "crossref": [ { "id": "A0A8V0YCS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16775", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16775", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20355", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20355", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20362", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20362", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420251", "url": "https://www.ncbi.nlm.nih.gov/gene/420251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420251", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQCSISL", "url": "https://omabrowser.org/oma/group/HQCSISL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCS7", "url": "https://www.orthodb.org/?gene=A0A8V0YCS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11685", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11685", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFNPLLMSDLDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISLGSLFRRKKDTKRKSRDLNGGVDGIASIESIHSEMCTDKNSIFSTCTSSDNGTTSSSKPSGDFMECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECSERFNPHDIRLILNDDILMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPAKFRHNSGSSSVDDGSAAGRSNAACSSACVPESKSGATKWSKETTAGKKCKGKLRKKSSMKINETREDMDAQLLEQQSTNSSEFDSPSLSDSIPSVADSHSSHFSEFSCSDMESMKTSCSHGSSDYHTRFTTVSVLPEVENDRLENSPQASGIPMPVPAAPGTDVQQLSYIAEESINNGSSTDVGLGVDETLKEANNNHSQRAAELSAAIQTEI", "length": 819, "header": "tr|A0A8V0YCS7-1|A0A8V0YCS7_CHICK Isoform 1 of RBR-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RNF19A PE=3 SV=1 CANONICAL=A0A8V0YCS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7/entry", "sequence": { "sequence": "MRFNPLLMSDLDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISLGSLFRRKKDTKRKSRDLNGGVDGIASIESIHSEMCTDKNSIFSTCTSSDNGTTSSSKPSGDFMECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECSERFNPHDIRLILNDDILMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDISKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPAKFRHNSGSSSVDDGSAAGRSNAACSSACVPESKSGATKWSKETTAGKKCKGKLRKKSSMKINETREDMDAQLLEQQSTNSSEFDSPSLSDSIPSVADSHSSHFSEFSCSDMESMKTSCSHGSSDYHTRFTTVSVLPEVENDRLENSPQASGIPMPVPAAPGTDVQQLSYIAEESINNGSSTDVGLGVDETLKEANNNHSQRAAELSAAIQTEI", "length": 819, "header": "tr|A0A8V0YCS7-1|A0A8V0YCS7_CHICK Isoform 1 of RBR-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RNF19A PE=3 SV=1 CANONICAL=A0A8V0YCS7-1" }, "locus": { "chromosome": "2", "start_pos": 128042797, "end_pos": 128023281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027166.1", "url": "https://www.ensembl.org/id/ENSGALT00010027166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015465.1", "url": "https://www.ensembl.org/id/ENSGALP00010015465.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 415, "start_aa": "Thr", "end_pos": 415, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr415", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420251", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LLQ3-1", "protein_name": "RBR-type E3 ubiquitin transferase", "gene_name": "Rnf19a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEQEISFIFKYNEGLCMNIDSDSVLMSILDMSLHQQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELTGGVDGIASIESIRSEVCAEKNSIFSTNASSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTMRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDRITTFTLTQRFFIVVTWIRREREGNSMEVQVDIESKPFKFRHHSGSSSVDDGGAARGHASGSSSGLPEGKSSATKWSKEATGGKKSKSGKLRKKGNTKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSGSLLSKTASCSEVPQPSHAADERATSSGGGKAAVDVCFGDALRETNNNHSHQAADLKVAVQTEI", "length": 861 }, "evidence": [ { "id": "A0A8V0YCS7", "url": "https://omabrowser.org/oma/group/A0A8V0YCS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BIP5-1", "protein_name": "RBR-type E3 ubiquitin transferase", "gene_name": "RNF19A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQEQEIDFIFKYNEGLCVNTDPDSILMSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQVGDFIECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVEDGSATRSHPGGSSGGLPEGKSSATKWSKEATAGKKSKSGKLRKKSNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSTDYHARFATVNILPEVENDRLENSPHQCSISVLTQTASCSEVPQLNHIAEEHGNSGIKPSVDLYFGSALKETNNNHSHQTMELKVAIQTDI", "length": 838 }, "evidence": [ { "id": "A0A8V0YCS7", "url": "https://omabrowser.org/oma/group/A0A8V0YCS7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P50636-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "Rnf19a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQEQEISFIFKYNEGLCMNIDSDSILMSILDMSLHQQMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDSKRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPFKFRHNSGSSSVDDSGATRGHTGGASSGLPEGKSSATKWSKEATGGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSSALLSKAASCSDVPQPSHAADEHGTSRSGGKPMVDLCFGDALRETNNNHSHQTADLKVAVQTEI", "length": 840 }, "evidence": [ { "id": "A0A8V0YCS7", "url": "https://omabrowser.org/oma/group/A0A8V0YCS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2VJ60-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "RNF19A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQEQEIGLLSKYNEGLCINTDPNSILMSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKENKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSAARSHPGGLSGGLPEGKSSATKWSKEATAGKKSKSGKLRKKSNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSTDYHARFATVNILPEVENDRLENSPHQCSISVLTKTASCSEDPQLNHIAEEHSNNGIRPNVDLYFGNALKETNNNHSHQTMELKVAIQTDI", "length": 838 }, "evidence": [ { "id": "A0A8V0YCS7", "url": "https://omabrowser.org/oma/group/A0A8V0YCS7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NV58-1", "protein_name": "E3 ubiquitin-protein ligase RNF19A", "gene_name": "RNF19A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI", "length": 838 }, "evidence": [ { "id": "A0A8V0YCS7", "url": "https://omabrowser.org/oma/group/A0A8V0YCS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" }, { "id": "PS51873", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51873" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 332, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.31", "ec_name": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "2.3.2.31", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.31" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 415 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCU7-1", "uniprot_ac": "A0A8V0YCU7", "uniprot_id": "A0A8V0YCU7_CHICK", "mass": { "chemical_mass": 33048.0, "monoisotopic_mass": 33048.0 }, "refseq": {}, "gene_names": [ { "name": "ART4", "type": "recommended", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ] } ], "protein_names": [ { "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.31", "type": "synonym", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7/entry#names_and_taxonomy" } ] }, { "name": "Mono(ADP-ribosyl)transferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ART4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7", "locus": { "chromosome": "1", "start_pos": 48091759, "end_pos": 48087190, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012098", "url": "https://www.ensembl.org/id/ENSGALG00010012098" } ] } } ], "crossref": [ { "id": "A0A8V0YCU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCU7", "url": "https://www.orthodb.org/?gene=A0A8V0YCU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19149", "url": "https://www.rhea-db.org/rhea/19149", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMLLLASILLLILQRLAGSHLMMDMALHSFDDQYLGCREQMMEELERGDYFQKEIAANKNYSSLWKKAQEALLKSSVGLLREMHDSHATALMAYTMNSSLHSQLNWATSTAGRSPEQYRHNFSFKYFHFYLTTAIQIMKQWQSSKDNVGKRHCYRVHRGVKDLYIKATVGSMVRFGRFTSTSRLWNEAQKFGNETLFTVTTCLGAAMQGFSYYTSEKEVLIPPYEIFLVKNFFRTRCGNRLHLHSVGNYSKYHCQLLEASRIKNGGSPASAAIILPSVIGVFLCLAKQ", "length": 289, "header": "tr|A0A8V0YCU7-1|A0A8V0YCU7_CHICK Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Gallus gallus OX=9031 GN=ART4 PE=3 SV=1 CANONICAL=A0A8V0YCU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7/entry", "sequence": { "sequence": "MSMLLLASILLLILQRLAGSHLMMDMALHSFDDQYLGCREQMMEELERGDYFQKEIAANKNYSSLWKKAQEALLKSSVGLLREMHDSHATALMAYTMNSSLHSQLNWATSTAGRSPEQYRHNFSFKYFHFYLTTAIQIMKQWQSSKDNVGKRHCYRVHRGVKDLYIKATVGSMVRFGRFTSTSRLWNEAQKFGNETLFTVTTCLGAAMQGFSYYTSEKEVLIPPYEIFLVKNFFRTRCGNRLHLHSVGNYSKYHCQLLEASRIKNGGSPASAAIILPSVIGVFLCLAKQ", "length": 289, "header": "tr|A0A8V0YCU7-1|A0A8V0YCU7_CHICK Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Gallus gallus OX=9031 GN=ART4 PE=3 SV=1 CANONICAL=A0A8V0YCU7-1" }, "locus": { "chromosome": "1", "start_pos": 48089688, "end_pos": 48087210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028997.1", "url": "https://www.ensembl.org/id/ENSGALT00010028997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016756.1", "url": "https://www.ensembl.org/id/ENSGALP00010016756.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" }, { "name": "cytolytic granule", "id": "GO:0044194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to antibiotic", "id": "GO:0046677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" }, { "name": "NAD+-protein-arginine ADP-ribosyltransferase activity", "id": "GO:0106274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19149", "name": "", "equation": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9K0-1", "P55806-1", "P55807-1", "Q92080-1", "A0A8V0X9F6-1", "A0A8V0X5H1-1", "A0A8V0XCF8-1", "A0A8V0XHM3-1", "A0A8V0YCU7-1" ], "evidence": [ { "id": "19149", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19149" } ] }, { "id": "R-GGA-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-2197633" ], "enzyme_list": [ "A0A8V0XCF8-1", "A0A8V0YRT8-1", "A0A8V0ZZE4-1", "A0A8V0Z2E4-1", "F1NN44-1", "A0A8V0XZX7-1", "A0A8V0Y5N7-1", "A0A8V0YCU7-1" ], "evidence": [ { "id": "R-GGA-8940388", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8940388" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2197633", "participant_name": "PI [extracellular region]", "crossref": [ { "id": "57880", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X5H1", "gene_name": "ART1D", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0X5H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5H1" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0X5H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5H1" } ] } ] }, { "uniprot_ac": "A0A8V0X9F6", "gene_name": "ART1A", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0X9F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9F6" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0X9F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9F6" } ] } ] }, { "uniprot_ac": "A0A8V0X9K0", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0X9K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K0" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0X9K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K0" } ] } ] }, { "uniprot_ac": "A0A8V0XCF8", "gene_name": "ART1", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0XCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCF8" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0XCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCF8" } ] } ] }, { "uniprot_ac": "A0A8V0XHM3", "gene_name": "ART1C", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0XHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHM3" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0XHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHM3" } ] } ] }, { "uniprot_ac": "A0A8V0XZX7", "gene_name": "GPLD1", "activity": [ { "ec_number": "3.1.4.50", "activity": "[protein]-C-terminal carboxyl phosphoethanolamide-(1-radyl-2-octadecanoyl)-GPI(deacylinositol-H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-glycosylinositol (deacylinositol-H7) + 1-radyl-2-octadecanoyl-sn-glycero-3-phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZX7" } ] }, { "ec_number": "3.1.4.50", "activity": "", "evidence": [ { "id": "A0A8V0XZX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZX7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5N7", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] } ] }, { "uniprot_ac": "A0A8V0YCU7", "gene_name": "ART4", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU7" } ] } ] }, { "uniprot_ac": "A0A8V0YRT8", "gene_name": "XPNPEP2", "activity": [ { "ec_number": "3.4.11.9", "activity": "Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.", "evidence": [ { "id": "A0A8V0YRT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRT8" } ] }, { "ec_number": "3.4.11.9", "activity": "", "evidence": [ { "id": "A0A8V0YRT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRT8" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E4", "gene_name": "ALPI", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8V0Z2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E4" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "P55806", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "P55806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55806" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "P55806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55806" } ] } ] }, { "uniprot_ac": "P55807", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "P55807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55807" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "P55807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55807" } ] } ] }, { "uniprot_ac": "Q92080", "gene_name": "MADPRT", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "Q92080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92080" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "Q92080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92080" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.2.31", "ec_name": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "2.4.2.31", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.31" }, { "id": "2.4.2.31", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.2.31" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCV1-1", "uniprot_ac": "A0A8V0YCV1", "uniprot_id": "A0A8V0YCV1_CHICK", "mass": { "chemical_mass": 78701.0, "monoisotopic_mass": 78701.0 }, "refseq": {}, "gene_names": [ { "name": "HAL", "type": "recommended", "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ] } ], "protein_names": [ { "name": "Histidine ammonia-lyase", "type": "recommended", "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1/entry#names_and_taxonomy" } ] }, { "name": "4.3.1.3", "type": "synonym", "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1", "locus": { "chromosome": "1", "start_pos": 45730979, "end_pos": 45743641, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011891", "url": "https://www.ensembl.org/id/ENSGALG00010011891" } ] } } ], "crossref": [ { "id": "A0A8V0YCV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00332", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00332", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCV1", "url": "https://www.orthodb.org/?gene=A0A8V0YCV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJS7", "url": "https://www.orthodb.org/?gene=A0A8V0YJS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70921", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70921", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "21232", "url": "https://www.rhea-db.org/rhea/21232", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHRSHLFTKVGISGGGFLPLSAQDTAIQSAILPCVNVRLLHSAAALRRGTVWGGNMPRYTVHVRGEWLAVPCPHGTNTVGWLGKEAVRRYMKNKPDNGGFTSVEEVKFFVRRCKGLGLLDLDDTVEDALEDNEFVEVVIEGDIMSPDFIPSQPEGVHLYSKYREPEQYISLDGNSLTTQDLVNLGKGLYKIKLTPEAEAKVKQSREVIERIVKEQTVVYGITTGFGKFARTVIPNSKLMELQMNLVRSHSAGVGKPLTPERSRMLLALRINVLAKGYSGISLETLQQVIEAFNASCLPYIPEKGTVGASGDLAPLSHLALGLTGEGKMWSPKSGWADAKYVLEAHGLKPITLKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQAEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTMRCCPQVHGVVNDTIAFVKDIMTTEINSATDNPMVFAERAETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVTEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWSARKALRVIEHVEQVLAIELLAACQGIEFLRPLRTTTPLEKVYDLVRSVVRPWMKDRFMAPDIEAAHRLLVEQKVWEVAEPYIEKYRREHIPESRPGSPTAFSLGSLERKTHDGHNHRHHSEL", "length": 715, "header": "tr|A0A8V0YCV1-1|A0A8V0YCV1_CHICK Isoform 1 of Histidine ammonia-lyase OS=Gallus gallus OX=9031 GN=HAL PE=1 SV=1 CANONICAL=A0A8V0YCV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1/entry", "sequence": { "sequence": "MHRSHLFTKVGISGGGFLPLSAQDTAIQSAILPCVNVRLLHSAAALRRGTVWGGNMPRYTVHVRGEWLAVPCPHGTNTVGWLGKEAVRRYMKNKPDNGGFTSVEEVKFFVRRCKGLGLLDLDDTVEDALEDNEFVEVVIEGDIMSPDFIPSQPEGVHLYSKYREPEQYISLDGNSLTTQDLVNLGKGLYKIKLTPEAEAKVKQSREVIERIVKEQTVVYGITTGFGKFARTVIPNSKLMELQMNLVRSHSAGVGKPLTPERSRMLLALRINVLAKGYSGISLETLQQVIEAFNASCLPYIPEKGTVGASGDLAPLSHLALGLTGEGKMWSPKSGWADAKYVLEAHGLKPITLKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQAEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTMRCCPQVHGVVNDTIAFVKDIMTTEINSATDNPMVFAERAETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVTEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWSARKALRVIEHVEQVLAIELLAACQGIEFLRPLRTTTPLEKVYDLVRSVVRPWMKDRFMAPDIEAAHRLLVEQKVWEVAEPYIEKYRREHIPESRPGSPTAFSLGSLERKTHDGHNHRHHSEL", "length": 715, "header": "tr|A0A8V0YCV1-1|A0A8V0YCV1_CHICK Isoform 1 of Histidine ammonia-lyase OS=Gallus gallus OX=9031 GN=HAL PE=1 SV=1 CANONICAL=A0A8V0YCV1-1" }, "locus": { "chromosome": "1", "start_pos": 45743442, "end_pos": 45731664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028436.1", "url": "https://www.ensembl.org/id/ENSGALT00010028436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016309.1", "url": "https://www.ensembl.org/id/ENSGALP00010016309.1" } ] } }, { "isoform_ac": "A0A8V0YJS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS7/entry", "sequence": { "sequence": "MPRYTVHVRGEWLAVPCPHGTNTVGWLGKEAVRRYMKNKPDNGGFTSVEEVKFFVRRCKGLGLLDLDDTVEDALEDNEFVEVVIEGDIMSPDFIPSQPEGVHLYSKYREPEQYISLDGNSLTTQDLVNLGKGLYKIKLTPEAEAKVKQSREVIERIVKEQTVVYGITTGFGKFARTVIPNSKLMELQMNLVRSHSAGVGKPLTPERSRMLLALRINVLAKGYSGISLETLQQVIEAFNASCLPYIPEKGTVGASGDLAPLSHLALGLTGEGKMWSPKSGWADAKYVLEAHGLKPITLKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQAEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTMRCCPQVHGVVNDTIAFVKDIMTTEINSATDNPMVFAERAETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVTEGGLNSGFMIAHCTAAALVLAIELLAACQGIEFLRPLRTTTPLEKVYDLVRSVVRPWMKDRFMAPDIEAAHRLLVEQKVWEVAEPYIEKYRREHIPESRPGSPTAFSLGSLERKTHDGHNHRHHSEL", "length": 615, "header": "tr|A0A8V0YJS7-1|A0A8V0YJS7_CHICK Computationally mapped isoform of Histidine ammonia-lyase OS=Gallus gallus OX=9031 GN=HAL PE=1 SV=1 CANONICAL=A0A8V0YCV1-1" }, "locus": { "chromosome": "1", "start_pos": 45743277, "end_pos": 45731664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028434.1", "url": "https://www.ensembl.org/id/ENSGALT00010028434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016307.1", "url": "https://www.ensembl.org/id/ENSGALP00010016307.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-70921", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70921", "resource": "Reactome", "description": "Histidine catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histidine ammonia-lyase activity", "id": "GO:0004397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-histidine catabolic process", "id": "GO:0006548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21232", "name": "", "equation": "L-histidine = trans-urocanate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YCV1-1" ], "evidence": [ { "id": "21232", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21232" } ] }, { "id": "R-GGA-70899", "name": "histidine => urocanate + NH4+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-30721" ], "enzyme_list": [ "A0A8V0YCV1-1" ], "evidence": [ { "id": "R-GGA-70899", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70899" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-30721", "participant_name": "UCA [cytosol]", "crossref": [ { "id": "ZINC000034633903", "database": "ZINC", "url": "" }, { "id": "17771", "database": "ChEBI", "url": "" }, { "id": "C00785", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YCV1", "gene_name": "HAL", "activity": [ { "ec_number": "4.3.1.3", "activity": "L-histidine = trans-urocanate + NH4(+).", "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ] }, { "ec_number": "4.3.1.3", "activity": "", "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV1" }, { "id": "PF12053", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Par3/HAL N-terminal", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 135, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.3.1.3", "ec_name": "L-histidine = trans-urocanate + NH4(+).", "evidence": [ { "id": "4.3.1.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.1.3" }, { "id": "4.3.1.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.3.1.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 463, "end_pos": 465 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YCV9-1", "uniprot_ac": "A0A8V0YCV9", "uniprot_id": "A0A8V0YCV9_CHICK", "mass": { "chemical_mass": 88915.0, "monoisotopic_mass": 88915.0 }, "refseq": { "ac": "NP_990013", "name": "serine/threonine-protein kinase SIK2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990013" }, "gene_names": [ { "name": "SIK1", "type": "recommended", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "name": "SIK1", "type": "synonym", 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kinase 2", "type": "synonym", "evidence": [ { "id": "NP_990013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990013" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF219232.1, ERR2365565.58406.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000020.1. On Sep 23, 2021 this sequence version replaced NP_990013.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990013" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9", "locus": { "chromosome": "1", "start_pos": 109984522, "end_pos": 109997486, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011896", "url": "https://www.ensembl.org/id/ENSGALG00010011896" } ] } } ], "crossref": [ { "id": "A0A8V0YCV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCV9", "database": "AlphaFoldDB", "categories": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVIMSEYASVPAPSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKRITISQIKQHKWMQADPSLRQQQSLSFSMQNYNSNLGDYNEQVLGIMQTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRSSQLSSRPATGRQQRPRSSEISNAEMPQDSLTSETLRSSLLYQQPQSLIQPSLQAEMDCDMNNPLQPVFFPVDPNFNGLFRNRSISPSSLLETTISEEVRQEKELEDEIKAYDHPIRIPSNTSRRHTLAEVTTHFYQHAPPCIVISSSASPTEGTSSDSCLTSSSNDSSVALSSCLAGQVMTGSPATARMTSAFLASQSDAPVLQVQGCMGGASLLPVSFQEGRRASDTSLTQGLKAFRQQLRKNARAKGFLGLNKIKGFARQVCQSSSSRAARSAMSPFQHAQPNTCIYSSSGSSREGRNLLEEVLQQQRMLQLQHHQLLQPACPQTSQTSATNGLPPSDSAGTCKASNSLLLSELQRENSFELAFGGNSQLLQPHFFGVSVSPVSSAAHLLDTHLYISSNVSPVGTTFSQQQSFSAQSPSYDAVTLQHGDCEMEDLTSNQLGKFVLVK", "length": 798, "header": "tr|A0A8V0YCV9-1|A0A8V0YCV9_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=SIK1 PE=4 SV=1 CANONICAL=A0A8V0YCV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9/entry", "sequence": { "sequence": "MVIMSEYASVPAPSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKRITISQIKQHKWMQADPSLRQQQSLSFSMQNYNSNLGDYNEQVLGIMQTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRSSQLSSRPATGRQQRPRSSEISNAEMPQDSLTSETLRSSLLYQQPQSLIQPSLQAEMDCDMNNPLQPVFFPVDPNFNGLFRNRSISPSSLLETTISEEVRQEKELEDEIKAYDHPIRIPSNTSRRHTLAEVTTHFYQHAPPCIVISSSASPTEGTSSDSCLTSSSNDSSVALSSCLAGQVMTGSPATARMTSAFLASQSDAPVLQVQGCMGGASLLPVSFQEGRRASDTSLTQGLKAFRQQLRKNARAKGFLGLNKIKGFARQVCQSSSSRAARSAMSPFQHAQPNTCIYSSSGSSREGRNLLEEVLQQQRMLQLQHHQLLQPACPQTSQTSATNGLPPSDSAGTCKASNSLLLSELQRENSFELAFGGNSQLLQPHFFGVSVSPVSSAAHLLDTHLYISSNVSPVGTTFSQQQSFSAQSPSYDAVTLQHGDCEMEDLTSNQLGKFVLVK", "length": 798, "header": "tr|A0A8V0YCV9-1|A0A8V0YCV9_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=SIK1 PE=4 SV=1 CANONICAL=A0A8V0YCV9-1" }, "locus": { "chromosome": "1", "start_pos": 109997239, "end_pos": 109987162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028446.1", "url": "https://www.ensembl.org/id/ENSGALT00010028446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016319.1", "url": "https://www.ensembl.org/id/ENSGALP00010016319.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395417", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395417", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "regulation of myotube differentiation", "id": "GO:0010830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "cardiac muscle cell differentiation", "id": "GO:0055007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "positive regulation of anoikis", "id": "GO:2000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000210", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "anoikis", "id": "GO:0043276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "negative regulation of triglyceride biosynthetic process", "id": "GO:0010868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "cAMP response element binding protein binding", "id": "GO:0008140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { 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"https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": 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}, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": 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"id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": 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"MAENTSHKSYRPLCVLTFKLNILLAGMNPFYFHAVNVILHCLVTLVLMYTCDKAVFKDCRLAFVTALFFAVHPIHTEAVTGIVGRADVLACLLFLLAFLSYNRSVDQLYVGEHFPPTASPFFLLLSLFLGTCAMLVKETGVTVFGVCLVYDFFSLSCNGLKLRNGGTHTRPVRHPAASLPASLPVQSRENGKHRFAHRTAWSSCHPEEPRSGGLPVPSKAIWAIRRSKVGEQGMEKNVYRWLFLTQRYPSQYIFGYLTANNNENFLYTARPFLKRAALVISYVILILYFRLWIMGGSMPMFSEQDNPASFSPHLLTRFLTYSYLLAFNAWLLLAPITLCYDWQVGSIPLVESVWDVRNLATVFLVLVLVLLSLHCLAEFKKLEHKEVLVGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLKKLTTWLNKWRITVLTLFALLLLLFSWKTVKQNEIWLSRESLFSSGVRTLPHNAKVHYNYANFLKDQGRNIEAIYHYKTALKLYPRHASALNNLGTLTKDVVEAKDYYRRALQLNPQHNRALFNLGNLLKSQGKKEEAVILLRDSIKYGPDFADAYSSLASLLAEQERLKEAEEVYKAGIENCPESSDLHNNYGVFLVDTGAPERAVSHYRQAIHLSPTHHVAMVNLGRLHRSLGQNKEAEAWYKRALKVSRKAEILSPLGALYYNTGRYEEALQVYREAASLQPSNKETRLALAQVLAMMGRTKEAEKMTNHVLDEDVECLECYRLLSAIYSKQEHYAKALEAIDKALQLKPKDPKIISELFFTKGNQLREQNLLDEAFENYKRAVELNSDQAQAWMNMGGIEHIKGNYITARGYYEKALQLVPNSKLLKENLAKLDRLEKRFQEVQEKDQT", "length": 885, "header": "tr|A0A8V0YE60-1|A0A8V0YE60_CHICK Isoform 1 of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC1 PE=3 SV=1 CANONICAL=A0A8V0YE60-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW5/entry", "sequence": { "sequence": "MSCFTGNELGSISGLNILLAGMNPFYFHAVNVILHCLVTLVLMYTCDKAVFKDCRLAFVTALFFAVHPIHTEAVTGIVGRADVLACLLFLLAFLSYNRSVDQLYVGEHFPPTASPFFLLLSLFLGTCAMLVKETGVTVFGVCLVYDFFSLSCNGLKLRNGGTHTRPVRHPAASLPASLPVQSRENGKHRFAHRTAWSSCHPEEPRSGGLPVPSKAIWAIRSYLTANNNENFLYTARPFLKRAALVISYVILILYFRLWIMGGSMPMFSEQDNPASFSPHLLTRFLTYSYLLAFNAWLLLAPITLCYDWQVGSIPLVESVWDVRNLATVFLVLVLVLLSLHCLAEFKKLEHKEVLVGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLKKLTTWLNKWRITVLTLFALLLLLFSWKTVKQNEIWLSRESLFSSGVRTLPHNAKVHYNYANFLKDQGRNIEAIYHYKTALKLYPRHASALNNLGTLTKDVVEAKDYYRRALQLNPQHNRALFNLGNLLKSQGKKEEAVILLRDSIKYGPDFADAYSSLASLLAEQERLKEAEEVYKAGIENCPESSDLHNNYGVFLVDTGAPERAVSHYRQAIHLSPTHHVAMVNLGRLHRSLGQNKEAEAWYKRALKVSRKAEILSPLGALYYNTGRYEEALQVYREAASLQPSNKETRLALAQVLAMMGRTKEAEKMTNHVLDEDVECLECYRLLSAIYSKQEHYAKALEAIDKALQLKPKDPKIISELFFTKGNQLREQNLLDEAFENYKRAVELNSDQAQAWMNMGGIEHIKGNYITARGYYEKALQLVPNSKLLKENLAKLDRLEKRFQEVQEKDQT", "length": 851, "header": "tr|A0A8V0YCW5-1|A0A8V0YE60_CHICK Computationally mapped isoform of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC1 PE=3 SV=1 CANONICAL=A0A8V0YE60-1" }, "locus": { "chromosome": "1", "start_pos": 59898973, "end_pos": 59757667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029017.1", "url": "https://www.ensembl.org/id/ENSGALT00010029017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016776.1", "url": "https://www.ensembl.org/id/ENSGALP00010016776.1" } ] } }, { "isoform_ac": "A0A8V0YE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60/entry", "sequence": { "sequence": "MAENTSHKSYRPLCVLTFKLNILLAGMNPFYFHAVNVILHCLVTLVLMYTCDKAVFKDCRLAFVTALFFAVHPIHTEAVTGIVGRADVLACLLFLLAFLSYNRSVDQLYVGEHFPPTASPFFLLLSLFLGTCAMLVKETGVTVFGVCLVYDFFSLSCNGLKLRNGGTHTRPVRHPAASLPASLPVQSRENGKHRFAHRTAWSSCHPEEPRSGGLPVPSKAIWAIRRSKVGEQGMEKNVYRWLFLTQRYPSQYIFGYLTANNNENFLYTARPFLKRAALVISYVILILYFRLWIMGGSMPMFSEQDNPASFSPHLLTRFLTYSYLLAFNAWLLLAPITLCYDWQVGSIPLVESVWDVRNLATVFLVLVLVLLSLHCLAEFKKLEHKEVLVGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLKKLTTWLNKWRITVLTLFALLLLLFSWKTVKQNEIWLSRESLFSSGVRTLPHNAKVHYNYANFLKDQGRNIEAIYHYKTALKLYPRHASALNNLGTLTKDVVEAKDYYRRALQLNPQHNRALFNLGNLLKSQGKKEEAVILLRDSIKYGPDFADAYSSLASLLAEQERLKEAEEVYKAGIENCPESSDLHNNYGVFLVDTGAPERAVSHYRQAIHLSPTHHVAMVNLGRLHRSLGQNKEAEAWYKRALKVSRKAEILSPLGALYYNTGRYEEALQVYREAASLQPSNKETRLALAQVLAMMGRTKEAEKMTNHVLDEDVECLECYRLLSAIYSKQEHYAKALEAIDKALQLKPKDPKIISELFFTKGNQLREQNLLDEAFENYKRAVELNSDQAQAWMNMGGIEHIKGNYITARGYYEKALQLVPNSKLLKENLAKLDRLEKRFQEVQEKDQT", "length": 885, "header": "tr|A0A8V0YE60-1|A0A8V0YE60_CHICK Isoform 1 of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC1 PE=3 SV=1 CANONICAL=A0A8V0YE60-1" }, "locus": { "chromosome": "1", "start_pos": 59898973, "end_pos": 59752459, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029021.1", "url": "https://www.ensembl.org/id/ENSGALT00010029021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016780.1", "url": "https://www.ensembl.org/id/ENSGALP00010016780.1" } ] } }, { "isoform_ac": "A0A8V0YGC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC1/entry", "sequence": { "sequence": "MAENTSHKSYRPLCVLTFKLNILLAGMNPFYFHAVNVILHCLVTLVLMYTCDKAVFKDCRLAFVTALFFAVHPIHTEAVTGIVGRADVLACLLFLLAFLSYNRSVDQLYVGEHFPPTASPFFLLLSLFLGTCAMLVKETGVTVFGVCLVYDFFSLSCNGLKLRNGGTHTRPVRHPAASLPASLPVQSRENGKHRFAHRTAWSSCHPEEPRSGGLPVPSKAIWAIRSYLTANNNENFLYTARPFLKRAALVISYVILILYFRLWIMGGSMPMFSEQDNPASFSPHLLTRFLTYSYLLAFNAWLLLAPITLCYDWQVGSIPLVESVWDVRNLATVFLVLVLVLLSLHCLAEFKKLEHKEVLVGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLKKLTTWLNKWRITVLTLFALLLLLFSWKTVKQNEIWLSRESLFRLYPRHASALNNLGTLTKDVVEAKDYYRRALQLNPQHNRALFNLGNLLKSQGKKEEAVILLRDSIKYGPDFADAYSSLASLLAEQERLKEAEEVYKAGIENCPESSDLHNNYGVFLVDTGAPERAVSHYRQAIHLSPTHHVAMVNLGRLHRSLGQNKEAEAWYKRALKVSRKAEILSPLGALYYNTGRYEEALQVYREAASLQPSNKETRLALAQVLAMMGRTKEAEKMTNHVLDEDVECLECYRLLSAIYSKQEHYAKALEAIDKALQLKPKDPKIISELFFTKGNQLREQNLLDEAFENYKRAVELNSDQAQAWMNMGGIEHIKGNYITARGYYEKALQLVPNSKLLKENLAKLDRLEKRFQEVQEKDQT", "length": 818, "header": "tr|A0A8V0YGC1-1|A0A8V0YGC1_CHICK Computationally mapped isoform of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC1 PE=3 SV=1 CANONICAL=A0A8V0YE60-1" }, "locus": { "chromosome": "1", "start_pos": 59898973, "end_pos": 59752459, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029022.1", "url": "https://www.ensembl.org/id/ENSGALT00010029022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016781.1", "url": "https://www.ensembl.org/id/ENSGALP00010016781.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE60" }, { "id": "PF08409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1736", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 368, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.109", "ec_name": "a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+).", "evidence": [ { "id": "2.4.1.109", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.109" }, { "id": "2.4.1.109", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.109" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YD24-1", "uniprot_ac": "A0A8V0YD24", "uniprot_id": "A0A8V0YD24_CHICK", "mass": { "chemical_mass": 94307.0, "monoisotopic_mass": 94307.0 }, "refseq": { "ac": "XP_040555216", "name": "uncharacterized protein LOC112532301", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555216" }, "gene_names": [ { "name": "LOC112532301", "type": "recommended", "evidence": [ { "id": "A0A8V0YD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ] }, { "name": "LOC112532301", "type": "synonym", "evidence": [ { "id": "XP_040555216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555216" } ] } ], "protein_names": [ { "name": "Threonylcarbamoyl-AMP synthase", "type": "recommended", "evidence": [ { "id": "A0A8V0YD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.87", "type": "synonym", "evidence": [ { "id": "A0A8V0YD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC112532301", "type": "synonym", "evidence": [ { "id": "XP_040555216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555216" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040555216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555216" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112532301", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24", "locus": {} } ], "crossref": [ { "id": "A0A8V0YD24", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD24", "database": "AlphaFoldDB", "categories": [] }, { "id": "112532301", "url": "https://www.ncbi.nlm.nih.gov/gene/112532301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SFGYMKS", "url": "https://omabrowser.org/oma/group/SFGYMKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD24", "url": "https://www.orthodb.org/?gene=A0A8V0YD24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17490:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17490:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040555216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555216", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36407", "url": "https://www.rhea-db.org/rhea/36407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSTAGFAAVFYSEPAVLGLLANVISAFLLCLQNFATAHTGLKPQGAEDVLAGVHLILIGGFVQLLAGFLAFRKYDHLGGAAFLTFSALWSSYGTTRIISAAYPPMQNITLSSGNASQLLSSTMTHLSTSQSAVAGLVAYISISFILSFCSATVNYIMPFIFGAIALALVFEAVALFGQWALIVSGVIELVIVLCGLYGAMALLLKGITQRYILPGFGHPLFNVLLLGSAQKSSSKAIGEEKKKNTKYAEPMALGNICDTVSPFIFAFYFFGYMKTFCVGAAWISIISSCQLLSSFYSYLRGDVYYTTKFGAHSLFWLVMSWEEFVLTTFLEPGKAQESRLGMFGGWFFLVVACMLFLMSTHKDTLEMLQNASFIILTSAFIHQIPLSGAYPFLGAACSLCTALSMYATFASLINSIGEKALIPIGKQAMSSSALQTTLMAAKIRFTRSKNLPSGTKAEVPDALFYICNGLAAVSAIQGTLSDPSRQQLSIPSVLIPGAIVQLYVCRIQVQGGRRFGCVLPFCYAAFWGAWTWLRFAGHLMNIGAGNSEGFTAGAIAFLVLNAFLMILASSFNVVLLCMTLAVELLTICFLLFTLENLPLPFEIVILCIFGIICFYGATASLANSMFGKDLMMMGPSLFTAESSKKNTEEPPPCICPKSHCTSGLRTIADLLNTGAVCGVPTDTVYALAASCRHPQAIEKVYRIKDRPQEKPICIFISNLDQLRAAAPPISPLLWEFMENVYPGGVGCIIKKGEWLKKLGVGEGYSRVGTQDSIMIRVPDLTVLVHLIDMTGPLAITSANPSGEVDSTHHDMVISRLGHKLEGVLCDGESDEVVASTVVNCTRIDESGITILREGCIPASKVMQIFERVKNRAV", "length": 874, "header": "tr|A0A8V0YD24-1|A0A8V0YD24_CHICK Isoform 1 of Threonylcarbamoyl-AMP synthase OS=Gallus gallus OX=9031 GN=LOC112532301 PE=3 SV=1 CANONICAL=A0A8V0YD24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24/entry", "sequence": { "sequence": "MVSTAGFAAVFYSEPAVLGLLANVISAFLLCLQNFATAHTGLKPQGAEDVLAGVHLILIGGFVQLLAGFLAFRKYDHLGGAAFLTFSALWSSYGTTRIISAAYPPMQNITLSSGNASQLLSSTMTHLSTSQSAVAGLVAYISISFILSFCSATVNYIMPFIFGAIALALVFEAVALFGQWALIVSGVIELVIVLCGLYGAMALLLKGITQRYILPGFGHPLFNVLLLGSAQKSSSKAIGEEKKKNTKYAEPMALGNICDTVSPFIFAFYFFGYMKTFCVGAAWISIISSCQLLSSFYSYLRGDVYYTTKFGAHSLFWLVMSWEEFVLTTFLEPGKAQESRLGMFGGWFFLVVACMLFLMSTHKDTLEMLQNASFIILTSAFIHQIPLSGAYPFLGAACSLCTALSMYATFASLINSIGEKALIPIGKQAMSSSALQTTLMAAKIRFTRSKNLPSGTKAEVPDALFYICNGLAAVSAIQGTLSDPSRQQLSIPSVLIPGAIVQLYVCRIQVQGGRRFGCVLPFCYAAFWGAWTWLRFAGHLMNIGAGNSEGFTAGAIAFLVLNAFLMILASSFNVVLLCMTLAVELLTICFLLFTLENLPLPFEIVILCIFGIICFYGATASLANSMFGKDLMMMGPSLFTAESSKKNTEEPPPCICPKSHCTSGLRTIADLLNTGAVCGVPTDTVYALAASCRHPQAIEKVYRIKDRPQEKPICIFISNLDQLRAAAPPISPLLWEFMENVYPGGVGCIIKKGEWLKKLGVGEGYSRVGTQDSIMIRVPDLTVLVHLIDMTGPLAITSANPSGEVDSTHHDMVISRLGHKLEGVLCDGESDEVVASTVVNCTRIDESGITILREGCIPASKVMQIFERVKNRAV", "length": 874, "header": "tr|A0A8V0YD24-1|A0A8V0YD24_CHICK Isoform 1 of Threonylcarbamoyl-AMP synthase OS=Gallus gallus OX=9031 GN=LOC112532301 PE=3 SV=1 CANONICAL=A0A8V0YD24-1" }, "locus": { "chromosome": "4", "start_pos": 11285367, "end_pos": 11277219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029087.1", "url": "https://www.ensembl.org/id/ENSGALT00010029087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016846.1", "url": "https://www.ensembl.org/id/ENSGALP00010016846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9QKV1-1", "protein_name": "Threonylcarbamoyl-AMP synthase", "gene_name": "si:ch211-153b23.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASDGGFPASFYGEPGVLGLLANGISAFLVLLQNFHGARTGVPAEGVENILAGVHLILIGGLCQLVAGLLSFRKYDHLSGTSFVGYAALWASYGATRIYLGANQQSPNPFNESSMANSTFLDMNTNTGSINTTDIPLYIKESAIAGLVPYILLSFLLAFCSATVNYIMPFVFGAITLTLIFEAVGLVAGWALVVSGILELLILLFAIYGSSALLIKGLTQRYVLKGFGNPLFNVLLLGTTNAGSSQSLGQEKKKNTKYAEPMALGFFCDTVSPFIFAFYAFHYFPSNSVAAIWITINSAAQLLSSYYAYLRQDCYHATKFGLHCMFWLVKTWEEYVVSATTGQIEADNVRPAMVGNWFFLSAALVFCIASLNKDTLELIHNSFFALVTISTISQIPVKHYYMFFGVACSLFTLLSFYGTFARLINTIAEKSLIPVGPQPVSNESLQKHLSYLKKSKLIEPEDKGAQIPDALFYLCNGLAALSAIHNNQSNLAFFDLTVPWVLIPGAIMQAYISRLQVQGGQKFGSVVPSFYVAIWATWCWFRFAGHRLQLSTESAYGFAAGAIAFLVINAFLILVAAYGNLVNLALITVMEVIIVCFLLSTLGRLPYQLEVAMLAIFAIICLYGMLASLVNGMFSKTLIPVGPALIKDKKKNKSETTYPCLIANSRETSGLLKIAKLLENNGVCGIPTDTVYALAASCKNPSAIEKIYTIKDRPAEKPICICISSVEQLVAAKPPFSPLLWEFMRNVYPGGISCIVPKGDWLLKLGVGPAYDRVGTRESIMIRVPDHTATAHLCEFTGPLAITSANPSGEADSTHHDMVINRLGHKIEGVLCDGESNEVVASTVVNCLKIDEGAISILREGCVPALKVRQIFERVKNSML", "length": 880 }, "evidence": [ { "id": "A0A8V0YD24", "url": "https://omabrowser.org/oma/group/A0A8V0YD24/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" }, { "name": "L-threonylcarbamoyladenylate synthase", "id": "GO:0061710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061710", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36407", "name": "", "equation": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIR7-1", "A0A8V0YBX9-1", "A0A8V0YD24-1" ], "evidence": [ { "id": "36407", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36407" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YBX9", "gene_name": "LOC428714", 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"2.7.7.87", "ec_name": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.", "evidence": [ { "id": "2.7.7.87", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.87" }, { "id": "2.7.7.87", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.87" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 115, "end_pos": 117 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 840, "end_pos": 842 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"length": 1061, "header": "tr|A0A8V0YD39-1|A0A8V0YD39_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase B OS=Gallus gallus OX=9031 GN=INPP5B PE=1 SV=1 CANONICAL=A0A8V0YD39-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39/entry", "sequence": { "sequence": 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"length": 1061, "header": "tr|A0A8V0YD39-1|A0A8V0YD39_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase B OS=Gallus gallus OX=9031 GN=INPP5B PE=1 SV=1 CANONICAL=A0A8V0YD39-1" }, "locus": { "chromosome": "23", "start_pos": 3909153, "end_pos": 3894023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031902.1", "url": "https://www.ensembl.org/id/ENSGALT00010031902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018702.1", "url": "https://www.ensembl.org/id/ENSGALP00010018702.1" } ] } }, { "isoform_ac": "A0A8V0YJG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG2/entry", "sequence": { "sequence": "MDQSVAIQETLLDGATCRIISFALCASRGGMRSSLFLSPPSDPLDSHLGLPFLDPHRTPCREPWLWGRAWRADCWAWWSAAGGTRGIYVYTHRRMAITAEDVWLEKVIPITEGFAVEEVIPDGDLHVIGSDVTVRICSEGDGLTVQLPFGSHTRTFLQEVSKCSTEAVGSEGIKQNGKKLAVSPGWSQDSTDRSAPRQSKLKPEVTTEMVRSSNVMVSNVASILSEPKFGLRDTIVKSQLVQREDSYTYIQNFRFFVGTYNVNGQSPKESLQPWLRCDSAPPDIYCVGFQELDLSKEAFFFNDTPKEEEWFKAVTDSLHPDAKYAKVKLVRLVGIMLLLYVKADLALNISEVEIETVGTGIMGRMGNKGGVAIRFKFHNTSVCVVNSHLAAHMEEYERRNQDFKDICSRMQFCQSDPNLPPLTIGKHDVILWLGDLNYRLEELDVTKVKQLVDERAFPELCQYDQLKRQMNAKAVFEGFTEGEISFQPTYKYDAGCDEWDTSEKCRVPAWCDRILWKGQNIAQLSYRSHMALKISDHKPVSSVFDIGVKVVNEELYRKVFEEIVRSLDKVENANIPSVTLSQREFHFEDVKYMQLQVEKFTILNGQVPCQFEFISKPDEATYCKEWLIANPSKGFLLPGSEITIELELFVNKSTATRLNSGEEKLEDILVLHLDRGKDYFLSVTGNYLPSCFGSPIHTLCYMREPIQDMSAESIRNLTLMPLEMSDNATQAEKPLEIPKELWMMVDHLYRNASQQEDLFQQPGLRSEFEQIRDCLDKGMHDTLLGSNHSVAEALLLFLESLPEPVICYSFYSSCLECANNYVLSSQIISNLPECHKNVFEYLMAFLRELLKNSGKNNLDVNILASIFGGLLLRPPPGHPMPDITEKRKAQQFIHQFLLRENNLS", "length": 904, "header": "tr|A0A8V0YJG2-1|A0A8V0YJG2_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase B OS=Gallus gallus OX=9031 GN=INPP5B PE=1 SV=1 CANONICAL=A0A8V0YD39-1" }, "locus": { "chromosome": "23", "start_pos": 3909153, "end_pos": 3894023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031898.1", "url": "https://www.ensembl.org/id/ENSGALT00010031898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018699.1", "url": "https://www.ensembl.org/id/ENSGALP00010018699.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" }, { "id": "R-GGA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [], "go_annotation": { 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"https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" }, { "name": "inositol-1,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0052658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" }, { "name": "inositol phosphate phosphatase activity", "id": "GO:0052745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1059, "end_pos": 1061, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 944, "end_pos": 946, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALEDPVLIRPFRGHGAAVTGVGFSASAAELATSSLDRCLMIWKLKKQCRAYKFVGHTDAVTSVNFSPEGQLLASASQDRTVRLWIPCIHGESSVLKGHTASVRSVSFSHDGHLLVSASNDKSVKIWSVQRRRLLFSLFQHTHWVRCAKFSPDGRLIASCSEDKSVKIWDTVNKTCIDSFIDYEGFPNFADFNPSGTCIASAGSNHTVKLWDIRMNKLLQHYKVHRAEVNCVSFHPSGNYLITASTDGTLKILDLLEGRLIYTLHGHKGPVLSVAFSKGGEKFASGGADGQVLLWKTNFDSFDYKEVLKHHIRRIQTDDPPHLLDIYPRSPHLHDEKLQSVEVNPTFDVADTLTVDPPVVEISSSPSFGTLDDVSNEDLQYPSASVLATSSKRKSENESESAMHNVDKEIGLSPSLGNALENIVEQLDVLTLTISILEQRLTLTEDKLKECLENQQKILPQGRQEE", "length": 468, "header": "tr|A0A8V0YD61-1|A0A8V0YD61_CHICK Isoform 1 of POC1 centriolar protein homolog B OS=Gallus gallus OX=9031 GN=POC1B PE=3 SV=1 CANONICAL=A0A8V0YD61-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61/entry", "sequence": { "sequence": "MASALEDPVLIRPFRGHGAAVTGVGFSASAAELATSSLDRCLMIWKLKKQCRAYKFVGHTDAVTSVNFSPEGQLLASASQDRTVRLWIPCIHGESSVLKGHTASVRSVSFSHDGHLLVSASNDKSVKIWSVQRRRLLFSLFQHTHWVRCAKFSPDGRLIASCSEDKSVKIWDTVNKTCIDSFIDYEGFPNFADFNPSGTCIASAGSNHTVKLWDIRMNKLLQHYKVHRAEVNCVSFHPSGNYLITASTDGTLKILDLLEGRLIYTLHGHKGPVLSVAFSKGGEKFASGGADGQVLLWKTNFDSFDYKEVLKHHIRRIQTDDPPHLLDIYPRSPHLHDEKLQSVEVNPTFDVADTLTVDPPVVEISSSPSFGTLDDVSNEDLQYPSASVLATSSKRKSENESESAMHNVDKEIGLSPSLGNALENIVEQLDVLTLTISILEQRLTLTEDKLKECLENQQKILPQGRQEE", "length": 468, "header": "tr|A0A8V0YD61-1|A0A8V0YD61_CHICK Isoform 1 of POC1 centriolar protein homolog B OS=Gallus gallus OX=9031 GN=POC1B PE=3 SV=1 CANONICAL=A0A8V0YD61-1" }, "locus": { "chromosome": "1", "start_pos": 43423500, "end_pos": 43381642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031926.1", "url": "https://www.ensembl.org/id/ENSGALT00010031926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018723.1", "url": "https://www.ensembl.org/id/ENSGALP00010018723.1" } ] } }, { "isoform_ac": "A0A8V0YRD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD0/entry", "sequence": { "sequence": "MEAEEAMQSLQICRSHGCCDQREFLTRGTATCFSFPGSYCQTVDSLHYMFPFASHVPAWVLTDTEEHSHGESSVLKGHTASVRSVSFSHDGHLLVSASNDKSVKIWSVQRRRLLFSLFQHTHWVRCAKFSPDGRLIASCSEDKSVKIWDTVNKTCIDSFIDYEGFPNFADFNPSGTCIASAGSNHTVKLWDIRMNKLLQHYKVHRAEVNCVSFHPSGNYLITASTDGTLKILDLLEGRLIYTLHGHKGPVLSVAFSKGGEKFASGGADGQVLLWKTNFDSFDYKEVLKHHIRRIQTDDPPHLLDIYPRSPHLHDEKLQSVEVNPTFDVADTLTVDPPVVEISSSPSFGTLDDVSNEDLQYPSASVLATSSKRKSENESESAMHNVDKEIGLSPSLGNALENIVEQLDVLTLTISILEQRLTLTEDKLKECLENQQKILPQGRQEE", "length": 445, "header": "tr|A0A8V0YRD0-1|A0A8V0YD61_CHICK Computationally mapped isoform of POC1 centriolar protein homolog B OS=Gallus gallus OX=9031 GN=POC1B PE=3 SV=1 CANONICAL=A0A8V0YD61-1" }, "locus": { "chromosome": "1", "start_pos": 43409009, "end_pos": 43381642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031921.1", "url": "https://www.ensembl.org/id/ENSGALT00010031921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018718.1", "url": "https://www.ensembl.org/id/ENSGALP00010018718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "positive regulation of centriole elongation", "id": "GO:1903724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YD65-1", "uniprot_ac": "A0A8V0YD65", "uniprot_id": "A0A8V0YD65_CHICK", "mass": { "chemical_mass": 26102.0, "monoisotopic_mass": 26102.0 }, "refseq": { "ac": "NP_990515", "name": "ephrin-A5 isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" }, "gene_names": [ { "name": "EFNA5", "type": "recommended", "evidence": [ { "id": "A0A8V0YD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65" } ] }, { "name": "EFNA5", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] }, { "name": "RAGS", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] } ], "protein_names": [ { "name": "EPH-related receptor tyrosine kinase ligand 7", "type": "recommended", "evidence": [ { "id": "A0A8V0YD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65/entry#names_and_taxonomy" } ] }, { "name": "EPH-related receptor tyrosine kinase ligand 7", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] }, { "name": "LERK-7", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] }, { "name": "ephrin-A5 isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] }, { "name": "repulsive axon guidance signal protein", "type": "synonym", "evidence": [ { "id": "NP_990515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.20553.1, SRR13267649.6615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1. On Nov 20, 2021 this sequence version replaced NP_990515.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ] }, { "annotation": "Both soluble and membrane-attached ephrin-A5 inhibited growth of approximately half of each population of sensory axons in chick embryo. Ectopic expression of ephrin-A5 in ovo reduced arborization of cutaneous axons in skin on the limb", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" }, { "database": "PubMed", "id": "15949793", "url": "https://glygen.org/publication/PubMed/15949793" } ] }, { "annotation": "EphA4-ephrin-A5 signaling acts in a positive manner to constrain axons in the medial portion of the medial motor column to the rostral half-sclerotome [ephrin-A5]", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" }, { "database": "PubMed", "id": "14762125", "url": "https://glygen.org/publication/PubMed/14762125" } ] }, { "annotation": "Our data suggest that growth factors and the EphA-ephrinA system interact in a way that affects axon branching and synapse development.", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" }, { "database": "PubMed", "id": "19036963", "url": "https://glygen.org/publication/PubMed/19036963" } ] }, { "annotation": "Quantitative analysis of axon outgrowth shows that the stop reaction is controlled by a combination of the local ephrin concentration and the total amount of encountered ephrin.", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" }, { "database": "PubMed", "id": "16763203", "url": "https://glygen.org/publication/PubMed/16763203" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFNA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65", "locus": { "chromosome": "Z", "start_pos": 48925098, "end_pos": 48721980, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010266", "url": "https://www.ensembl.org/id/ENSGALG00010010266" } ] } } ], "crossref": [ { "id": "A0A8V0YD65", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD65", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10425", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10425", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396100", "url": "https://www.ncbi.nlm.nih.gov/gene/396100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396100", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCVKTIG", "url": "https://omabrowser.org/oma/group/NCVKTIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD65", "url": "https://www.orthodb.org/?gene=A0A8V0YD65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304", "database": "PANTHER", "categories": [ "Protein 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"https://www.uniprot.org/uniprotkb/A0A8V0YD65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHVEMLLLAVAALWVCVRGQEPGAKAVADRYAVYWNSTNPRFQQGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSSCDHISKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPANSCMKTIGVHDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPIRLLATLLFLLAMLLIL", "length": 228, "header": "tr|A0A8V0YD65-1|A0A8V0YD65_CHICK Isoform 1 of EPH-related receptor tyrosine kinase ligand 7 OS=Gallus gallus OX=9031 GN=EFNA5 PE=3 SV=1 CANONICAL=A0A8V0YD65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD65/entry", "sequence": { "sequence": 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cone navigation in substrate-bound ephrin gradients.", "journal": "Development (Cambridge, England)", "date": "2006-07", "authors": "von Philipsborn Anne C, Lang Susanne, Loeschinger J\u00fcrgen, Bernard Andr\u00e9, David Christian, Lehnert Dirk, Bonhoeffer Friedrich, Bastmeyer Martin", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990515" } ], "reference": [ { "type": "PubMed", "id": "16763203", "url": "https://glygen.org/publication/PubMed/16763203" } ] }, { "title": "A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2008-11-26", "authors": "Marler Katharine J M, Becker-Barroso Elena, Mart\u00ednez Albert, Llovera Marta, Wentzel Corinna, Poopalasundaram Subathra, Hindges Robert, Soriano Eduardo, Comella Joan, Drescher Uwe", "evidence": [ { "database": "RefSeq", "id": "NP_990515", "url": 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"https://www.ncbi.nlm.nih.gov/protein/XP_046795156" } ] } ], "protein_names": [ { "name": "WASH complex subunit 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046795156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795156" } ] }, { "name": "WASH complex subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YD94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046795156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795156" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WASHC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94", "locus": { "chromosome": "1", "start_pos": 59991889, "end_pos": 60032001, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012159", "url": "https://www.ensembl.org/id/ENSGALG00010012159" } ] } } ], "crossref": [ { "id": "A0A8V0YD94", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD94", "database": "AlphaFoldDB", "categories": [] }, { "id": "418145", "url": "https://www.ncbi.nlm.nih.gov/gene/418145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418145", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMDSPYE", "url": "https://omabrowser.org/oma/group/SMDSPYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD86", "url": "https://www.orthodb.org/?gene=A0A8V0YD86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD94", "url": "https://www.orthodb.org/?gene=A0A8V0YD94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH3", "url": "https://www.orthodb.org/?gene=A0A8V0YEH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23331:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23331:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11945", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11945", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046795156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795156", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YD86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLAALVRGTREGRAEARDGTMTTVAQKHFLEGQTYSVPLIQPDLRREEAVQQVADALQYLQKVSGDIFNRISQRVETSRAQLQAISERVTLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYCSIFAGAEDPAKQKWPRHKIQSKHRMLDEKSLQEKLKYFPVCVNTKIHQEDDAEEGLGSLPRNISSLSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVALETETEEKLFDAPLSITERGQLDRQVAENYFYVPDLGQVPEIDVPSYLPDLPGIAADLMYSADLGPGIAPSAPSSAIPELPTFSTESVEPSQADLQDPGLLPPPPPPPPPPPPVMPTTVPPPPPLPQPTAPSEPARTASEDSSKTVPAASVQGAPKEVVNPSTGRASLLESIRQAGGIGKANLRSVKERKLEKKKQKEQEQVRATGQGGDLMSDLFNKLVLRRKGISGKGPGASANPDAPGSPAGAFAHMSDSIPPLPPPQQPPGEEDEDDWES", "length": 498, "header": "tr|A0A8V0YD94-1|A0A8V0YD94_CHICK Isoform 1 of WASH complex subunit 1 OS=Gallus gallus OX=9031 GN=WASHC1 PE=1 SV=1 CANONICAL=A0A8V0YD94-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD86/entry", "sequence": { "sequence": "MHFSTCKRCQEIFSTGMRVETSRAQLQAISERVTLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYCSIFAGAEDPAKQKWPRHKIQSKHRMLDEKSLQEKLKYFPVCVNTKIHQEDDAEEGLGSLPRNISSLSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVALETETEEKLFDAPLSITERGQLDRQVAENYFYVPDLGQVPEIDVPSYLPDLPGIAADLMYSADLGPGIAPSAPSSAIPELPTFSTESVEPSQADLQDPGLLPPPPPPPPPPPPVMPTTVPPPPPLPQPTAPSEPARTASEDSSKTVPAASVQGAPKEVVNPSTGRASLLESIRQAGGIGKANLRSVKERKLEKKKQKEQEQVRATGQGGDLMSDLFNKLVLRRKGISGKGPGASANPDAPGSPAGAFAHMSDSIPPLPPPQQPPGEEDEDDWES", "length": 440, "header": "tr|A0A8V0YD86-1|A0A8V0YD94_CHICK Computationally mapped isoform of WASH complex subunit 1 OS=Gallus gallus OX=9031 GN=WASHC1 PE=1 SV=1 CANONICAL=A0A8V0YD94-1" }, "locus": { "chromosome": "1", "start_pos": 60020163, "end_pos": 59993411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029177.1", "url": "https://www.ensembl.org/id/ENSGALT00010029177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016920.1", "url": "https://www.ensembl.org/id/ENSGALP00010016920.1" } ] } }, { "isoform_ac": "A0A8V0YD94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94/entry", "sequence": { "sequence": "MAGLAALVRGTREGRAEARDGTMTTVAQKHFLEGQTYSVPLIQPDLRREEAVQQVADALQYLQKVSGDIFNRISQRVETSRAQLQAISERVTLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYCSIFAGAEDPAKQKWPRHKIQSKHRMLDEKSLQEKLKYFPVCVNTKIHQEDDAEEGLGSLPRNISSLSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVALETETEEKLFDAPLSITERGQLDRQVAENYFYVPDLGQVPEIDVPSYLPDLPGIAADLMYSADLGPGIAPSAPSSAIPELPTFSTESVEPSQADLQDPGLLPPPPPPPPPPPPVMPTTVPPPPPLPQPTAPSEPARTASEDSSKTVPAASVQGAPKEVVNPSTGRASLLESIRQAGGIGKANLRSVKERKLEKKKQKEQEQVRATGQGGDLMSDLFNKLVLRRKGISGKGPGASANPDAPGSPAGAFAHMSDSIPPLPPPQQPPGEEDEDDWES", "length": 498, "header": "tr|A0A8V0YD94-1|A0A8V0YD94_CHICK Isoform 1 of WASH complex subunit 1 OS=Gallus gallus OX=9031 GN=WASHC1 PE=1 SV=1 CANONICAL=A0A8V0YD94-1" }, "locus": { "chromosome": "1", "start_pos": 60031844, "end_pos": 59993411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029183.1", "url": "https://www.ensembl.org/id/ENSGALT00010029183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016925.1", "url": "https://www.ensembl.org/id/ENSGALP00010016925.1" } ] } }, { "isoform_ac": "A0A8V0YEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH3/entry", "sequence": { "sequence": "MTTVAQKHFLEGQTYSVPLIQPDLRREEAVQQVADALQYLQKVSGDIFNRISQRVETSRAQLQAISERVTLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYCSIFAGAEDPAKQKWPRHKIQSKHRMLDEKSLQEKLKYFPVCVNTKIHQEDDAEEGLGSLPRNISSLSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVALETETEEKLFDAPLSITERGQLDRQVAENYFYVPDLGQVPEIDVPSYLPDLPGIAADLMYSADLGPGIAPSAPSSAIPELPTFSTESVEPSQADLQDPGLLPPPPPPPPPPPPVMPTTVPPPPPLPQPTAPSEPARTASEDSSKTVPAASVQGAPKEVVNPSTGRASLLESIRQAGGIGKANLRSVKERKLEKKKQKEQEQVRATGQGGDLMSDLFNKLVLRRKGISGKGPGASANPDAPGSPAGAFAHMSDSIPPLPPPQQPPGEEDEDDWES", "length": 476, "header": "tr|A0A8V0YEH3-1|A0A8V0YEH3_CHICK Computationally mapped isoform of WASH complex subunit 1 OS=Gallus gallus OX=9031 GN=WASHC1 PE=1 SV=1 CANONICAL=A0A8V0YD94-1" }, "locus": { "chromosome": "1", "start_pos": 60020266, "end_pos": 59993411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029168.1", "url": "https://www.ensembl.org/id/ENSGALT00010029168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016913.1", "url": "https://www.ensembl.org/id/ENSGALP00010016913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418145", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418145", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LID2-1", "protein_name": "WASH complex subunit 1 isoform X1", "gene_name": "Washc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTPLKTQHCLVGQPYTVPLIQPDLRREEAIQQVADALQYLQSISGDIFSRISQRVELSRCQLQALRERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGALDPNLQRRPRYRVQSKHRPLDERALQEKLKYFPVCVNTKSEPEDEAEEGLGGLPSNISSISSLLLFNTTENLYKKYVFLDPLAGAVTKTHTMLGTEEEKLFDAPLSISKREQLEQQAPENYFYVPDLGQVPEIDVPSYLPDLPGIADDLMYNADLGPGIAPSAPGAIPELPTFHTEVAEPFQPELEDGALLAAPPPPPPPPPPPPPAPTVVVSAPQPPVFPEVATAPGQVAREEDRSSGVAHSASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGPGSGTSEGPAGAFTRMSDSIPPLPPPQQPAGDEDDDDWES", "length": 475 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A4IG59-1", "protein_name": "WASH complex subunit 1", "gene_name": "washc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRMTQKRYLEGQVYSVPLIQPDLRREEAVHQITDALQYLEMISTDIFTRVSESVEKNRAHLQSVTDRIKLAQARVQKIKGSKKATKVFSSAKYPAPEKLQDYSSIFTGAVDPASQKRPRIKVQSKLRPLDDKAQQEKLMYLPVCVNTKKRSEDETEEGLGSLPRNVNSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHTTLETEKEDKPFDAPLSITKREQLERQTAENYFYVPDLGQVPEIDVPSYLPDLPGIADDLMYSADLGPGFAPSVPASNSIPELPSFGTDHDESSGSDSQFKLEAPPPPPPPPPPPPEPTHVPVPPPGTSAAPPPPPPPPPMTADNTDASSPAPPTGTVKGAPSEVVQPSNGRASLLESIRNAGGIGKANLRNVKERKMEKKKQKEQEQVGATVSGGDLMSDLFNKLAMRRKGISGKGPAGQGDSSEAPASSGGAFARMSDVIPPLPAPQQSAADDEDDWEA", "length": 481 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A7Z063-1", "protein_name": "WASH complex subunit 1", "gene_name": "WASHC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPTGTQHSLAGQTYAVPLIQPDLRREEAIQQVADALQYLQKVSGDIFSRISQRVELSRSQLQAIGERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFMGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKFFPVCVNTKPEPEDEAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISRREQLERQVPENYFYVPDLGQVPDIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPGAIPELPTFHTEVAQPFKPDLEDGVLTARPPPPPPPPPPPAPAVLMSVPPPPPPPQAPPGQPAKGDDSGGASPSAPVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLAMRRKGISGKGPGSGASEGPGGAFARMSDSIPPLPPPQQPPGEEDEDDWES", "length": 471 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B2RYF7-1", "protein_name": "WASH complex subunit 1", "gene_name": "Washc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAVKTQHSLAGQVYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISQRVELSRRQLQAIGERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYNSVFTGALDPGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVSTKSEPEDEAEEGLGGLPSNISSISSLLLFNTTENLYKKYVFLDPLAGAVTKTHTMLGTEEEKLFDAPLSISKREQLEQPAPENYFYVPGLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPGAIPELPAFHTEVAEPFQPEREDGALLAPPPPPPPPPPPPPPAPTAVVSAPQPPMSPDVVTVTGKVAREEDSGSGEAHSASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGPGTGTSEGPGGAFSRMSDSIPPLPPPQQPAGDEDEDDWES", "length": 475 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54CK9-1", "protein_name": "WAS protein family homolog DDB_G0292878", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTQIYQVPVVSNGLRETESILQIVDSLEKLEKVFNDMYSTISARVSHEKSRIDNVANRLNNAQHKVNQIVGSKQAITVFSSAKYPADKKWGDYVPIYSGKHKLPFKPSHYHGLNSEDSPIKKRPEDSYLDVNDLVFIEKSIDTTSKEVEVKEGLGRIPAQIPSVSNLLLFNTQENPYKKYSNTLDNLSGGDGGEDDYTIFGDQLSKKKRLGDAPVTVKDGDSRIDAENVKIGYEPGTFEIPVYNFPSILPLPNVAENITWAAESQSIAPSQKATLNLLPTYDNSNSGSAPVNQSSGGDNNVNNNNNNNNSNNSTGIMQPPQPTNAPPPPPPPPQSANAPPPPPPPPVSAPPPFNPPSVNSNNDDDDDDDDDNGGGGGPGGAIGDLLADIRRGHKNRLKKADVGGDNGDGEDNKPPPVSDGGGGLMGDLFKKLALRRQSIATTKSTKKQSKSKKEDTDDQDGESDTDSSEWE", "length": 472 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7JW27-1", "protein_name": "WASH complex subunit 1", "gene_name": "wash", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEESPYLHSPYQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDALVGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADIFFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKRSLPPQNARRVASQSTQLTGEKQLAPAPHSLAHGTTKLATPAGDLRYNPAALAAPAIDVPLDLPDLPGIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVRRKSVGQCPSPVTAAPPPPPPPPPPPPPPPPAQTSAIPSPPPFPTKGAVKPLSPSLATPLNMPQPPPATEDPRSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVTGDLMADLHNKLMLRRKGISGSQNPVEATAGNPLMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDGWN", "length": 499 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VDD8-1", "protein_name": "WASH complex subunit 1", "gene_name": "Washc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPVKTQCSLAGQLYAVPLIQPDLRREEAIQQVADALQYLQNISGDIFSRISRRVELSRRQLQAISERVSLAQAKIEKIKGSKKAIKVFSSAKYPAPEHLQEYGSIFTGALDPGLQRRPRYRIQSKHRPLDERALQEKLKYFPVCVNTKSEPEDEAEEGLGGLPSNISSISSLLLFNTTENLYKKYVFLDPLAGAVTKTHTMLGTEEEKLFDAPLSISKREQLERQAPENYFYVPDLGQVPEIDVPSYLPDLPGVADDLMYSADLGPGIAPSAPGAIPELPAFHTEVAEPLQPELENEVLLAAPPPPPPPPPPPPPAPTALVSTPQPPMFPDMATAAGQVAREEDSSSSMAHTASVQGAPKEVVDPSSGRATLLESIRQAGGIGKAKLRSVKERKLEKKKQKEQEQVRATSQGGDLMSDLFNKLVMRRKGISGKGPSTGTSEGPGGAFSRMSDSIPPLPPPQQPAGDEDEEDWES", "length": 475 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQA3-1", "protein_name": "WAS protein family homolog 6", "gene_name": "WASH6P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFHEMQAHKNALGTSGEQQAADITGPTPHQGGWKQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPSIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKADLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDGSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPVPPPQQPQAEEDEDDWES", "length": 447 }, "evidence": [ { "id": "A0A8V0YD94", "url": "https://omabrowser.org/oma/group/A0A8V0YD94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD94" }, { "id": "PS51082", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH2", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 410, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 199, "end_pos": 201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YDA9-1", "uniprot_ac": "A0A8V0YDA9", "uniprot_id": "A0A8V0YDA9_CHICK", "mass": { "chemical_mass": 114185.0, "monoisotopic_mass": 114185.0 }, "refseq": {}, "gene_names": [ { "name": "TUBGCP3", "type": "recommended", "evidence": [ { "id": "A0A8V0YDA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9" } ] } ], "protein_names": [ { "name": "Tubulin gamma complex component 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YDA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUBGCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9", "locus": { "chromosome": "1", "start_pos": 137983754, "end_pos": 137933210, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013293", "url": "https://www.ensembl.org/id/ENSGALG00010013293" } ] } } ], "crossref": [ { "id": "A0A8V0YDA9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDA1", "url": "https://www.orthodb.org/?gene=A0A8V0YDA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDA9", "url": "https://www.orthodb.org/?gene=A0A8V0YDA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRI2", "url": "https://www.orthodb.org/?gene=A0A8V0YRI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLRLSAVLLKWRRRQRPSVQPAACTGRPAPPLRLPPCLPPLATASLFRPPGRRWRLRTKNPPTFCCRTSAAASWARAKVTAFPSAGPLGPLGREWPLGPRSVASSPASARGRCVGAAGGSLGRLPDAAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELVRQRREADAALFSELYRKLGSQGILKNKWSILYLLLSLSEDPRKQSNKVSSYATLFAQALPRDAHSTPYYYARPQSLPLNYQDRSAQSAQSSGSMGSSGISSINLYALNGPTPTPQSLLPGQSYQAPGVGDCLRQQLGSRLAWTLTASQPSLQSTTSKGFSNAVSRGVPRSRREGDSSGSVEITEANLVRDVLYVFQGIDGKNIKMCNSENCYKVEGKVSLSKSLRDTTSRLAELGWLHNKIRKYTDQRSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILGLVSHPVLNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMEQSKKVLLIGKSINFLHQVCHDQTPSTKMIAVAKSAESSKGAADLFTDLENAFQEKIDAAYFETSKYLLDVLNKKYNLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDNPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGHMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIIARCLLDSDSRVLLNQLRAVFDQIIELQNAQDAMYRAALEELQLRLQFEERKKQRELEGKWGVTASEEEEEKKRIKEFQDSIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHM", "length": 1007, "header": "tr|A0A8V0YDA9-1|A0A8V0YDA9_CHICK Isoform 1 of Tubulin gamma complex component 3 OS=Gallus gallus OX=9031 GN=TUBGCP3 PE=1 SV=1 CANONICAL=A0A8V0YDA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA1/entry", "sequence": { "sequence": "MQNIVRQRREADAALFSELYRKLGSQGILKNKWSILYLLLSLSEDPRKQSNKVSSYATLFAQALPRDAHSTPYYYARPQSLPLNYQDRSAQSAQSSGSMGSSGISSINLYALNGPTPTPQSLLPGQSYQAPGVGDCLRQQLGSRLAWTLTASQPSLQSTTSKGFSNAVSRGVPRSRREGDSSGSVEITEANLVRDVLYVFQGIDGKNIKMCNSENCYKVEGKVSLSKSLRDTTSRLAELGWLHNKIRKYTDQRSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILGLVSHPVLNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMEQSKKVLLIGKSINFLHQVCHDQTPSTKMIAVAKSAESSKGAADLFTDLENAFQEKIDAAYFETSKYLLDVLNKKYNLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDNPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGHMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIIARCLLDSDSRVLLNQLRAVFDQIIELQNAQDAMYRAALEELQLRLQFEERKKQRELEGKWGVTASEEEEEKKRIKEFQDSIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHM", "length": 849, "header": "tr|A0A8V0YDA1-1|A0A8V0YDA9_CHICK Computationally mapped isoform of Tubulin gamma complex component 3 OS=Gallus gallus OX=9031 GN=TUBGCP3 PE=1 SV=1 CANONICAL=A0A8V0YDA9-1" }, "locus": { "chromosome": "1", "start_pos": 137982757, "end_pos": 137945802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031974.1", "url": "https://www.ensembl.org/id/ENSGALT00010031974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018764.1", "url": "https://www.ensembl.org/id/ENSGALP00010018764.1" } ] } }, { "isoform_ac": "A0A8V0YDA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA9/entry", "sequence": { "sequence": "MPLRLSAVLLKWRRRQRPSVQPAACTGRPAPPLRLPPCLPPLATASLFRPPGRRWRLRTKNPPTFCCRTSAAASWARAKVTAFPSAGPLGPLGREWPLGPRSVASSPASARGRCVGAAGGSLGRLPDAAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELVRQRREADAALFSELYRKLGSQGILKNKWSILYLLLSLSEDPRKQSNKVSSYATLFAQALPRDAHSTPYYYARPQSLPLNYQDRSAQSAQSSGSMGSSGISSINLYALNGPTPTPQSLLPGQSYQAPGVGDCLRQQLGSRLAWTLTASQPSLQSTTSKGFSNAVSRGVPRSRREGDSSGSVEITEANLVRDVLYVFQGIDGKNIKMCNSENCYKVEGKVSLSKSLRDTTSRLAELGWLHNKIRKYTDQRSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILGLVSHPVLNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMEQSKKVLLIGKSINFLHQVCHDQTPSTKMIAVAKSAESSKGAADLFTDLENAFQEKIDAAYFETSKYLLDVLNKKYNLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDNPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGHMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIIARCLLDSDSRVLLNQLRAVFDQIIELQNAQDAMYRAALEELQLRLQFEERKKQRELEGKWGVTASEEEEEKKRIKEFQDSIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHM", "length": 1007, "header": "tr|A0A8V0YDA9-1|A0A8V0YDA9_CHICK Isoform 1 of Tubulin gamma complex component 3 OS=Gallus gallus OX=9031 GN=TUBGCP3 PE=1 SV=1 CANONICAL=A0A8V0YDA9-1" }, "locus": { "chromosome": "1", "start_pos": 137982757, "end_pos": 137933237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031984.1", "url": "https://www.ensembl.org/id/ENSGALT00010031984.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018774.1", "url": "https://www.ensembl.org/id/ENSGALP00010018774.1" } ] } }, { "isoform_ac": "A0A8V0YRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI2/entry", "sequence": { "sequence": "MATPDQKSPNVLLQNLCCRILGKSEVVRQRREADAALFSELYRKLGSQGILKNKWSILYLLLSLSEDPRKQSNKVSSYATLFAQALPRDAHSTPYYYARPQSLPLNYQDRSAQSAQSSGSMGSSGISSINLYALNGPTPTPQSLLPGQSYQAPGVGDCLRQQLGSRLAWTLTASQPSLQSTTSKGFSNAVSRGVPRSRREGDSSGSVEITEANLVRDVLYVFQGIDGKNIKMCNSENCYKVEGKVSLSKSLRDTTSRLAELGWLHNKIRKYTDQRSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILGLVSHPVLNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMEQSKKVLLIGKSINFLHQVCHDQTPSTKMIAVAKSAESSKGAADLFTDLENAFQEKIDAAYFETSKYLLDVLNKKYNLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETAVRATNAQFDNPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIWKGHMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIIARCLLDSDSRVLLNQLRAVFDQIIELQNAQDAMYRAALEELQLRLQFEERKKQRELEGKWGVTASEEEEEKKRIKEFQDSIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHM", "length": 871, "header": "tr|A0A8V0YRI2-1|A0A8V0YDA9_CHICK Computationally mapped isoform of Tubulin gamma complex component 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Classification" ] }, { "id": "A0A8V0YDF4", "url": "https://www.orthodb.org/?gene=A0A8V0YDF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046795368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795368", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFWNRSIRPWMEGYHGMMEHQDEHKNPWVKEFPYVWARYNMDCGLVAEQVEVTGDPVPYQEEKSFVPHVDRVVASLLRQMLGEGIVVMGSSPSNSPLHLISKDNGETLRLTLNFKAIHSVTPRQPTESLDRTDVAKVLSPRSRYFSTLDLSCASFAIPLTAASRRRFAFSFRGQQYLFTRLPPGFYLTNSIVHRRVACMLAQLPPEDKGWVSSYVDDMIISGRTREETESRTKRVLRLIQNTGFKVKLWKAQLVQPEVDYLGMKLSARGWELQASKLECIVNAPSPSDLRSLSSLLEKLCCHQDHVEDYQELVRPLKSLLNEEKWRWGQEQQQALRRLIKAVVTAPVLRFVDRSQPFIIRPTVYNETMGAALLQEDEQGRIVAIRFKSCVLKEHQVSYSPKEKQCMAVVRAVHKFQDLIGTAPIVIQMPHSPWKYLLRGDTETFCWPIPCKKQWNLLLVNGGKRMPAAPQRSDVLVHTAPLLHQLPSGVPHSDVWFTAGRRACVAALGFAATNLEERWLLGLMQHGSPADVELEAIRVLMQEHRSSKPLYVYANSQSVVQGLQNRDVKDRRVGDMQLWQSVLQWVSANPGVLHVGDSRDGEELKWNRKVVERAQSIQAWVLSSHGQRVWEPSKHERQEIVALSHVGHVGVTKMLKRVWQVARWEGDREQVARWVQCCSCTRSPPQPQRTEGPWSRLQLAHVKDLPLSSKGYSSLLVLLDEFSGWVDAFPMRKGNREEMVTEMVTLLQEHVVQRLGMPSCISMGHCERFLQDAVQMSLQMVVDVQFLLPNWVEAITTSLQRLAQSAGKHWADSLSLIMAALRAMCVRSAVLGPYQLCSHRPLVLRLSPVEGEAPPDPTESLLPWLARLREDRAEYKQRVQEAMGV", "length": 885, "header": "tr|A0A8V0YDF4-1|A0A8V0YDF4_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN=LOC121110417 PE=3 SV=1 CANONICAL=A0A8V0YDF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4/entry", "sequence": { "sequence": "MEFWNRSIRPWMEGYHGMMEHQDEHKNPWVKEFPYVWARYNMDCGLVAEQVEVTGDPVPYQEEKSFVPHVDRVVASLLRQMLGEGIVVMGSSPSNSPLHLISKDNGETLRLTLNFKAIHSVTPRQPTESLDRTDVAKVLSPRSRYFSTLDLSCASFAIPLTAASRRRFAFSFRGQQYLFTRLPPGFYLTNSIVHRRVACMLAQLPPEDKGWVSSYVDDMIISGRTREETESRTKRVLRLIQNTGFKVKLWKAQLVQPEVDYLGMKLSARGWELQASKLECIVNAPSPSDLRSLSSLLEKLCCHQDHVEDYQELVRPLKSLLNEEKWRWGQEQQQALRRLIKAVVTAPVLRFVDRSQPFIIRPTVYNETMGAALLQEDEQGRIVAIRFKSCVLKEHQVSYSPKEKQCMAVVRAVHKFQDLIGTAPIVIQMPHSPWKYLLRGDTETFCWPIPCKKQWNLLLVNGGKRMPAAPQRSDVLVHTAPLLHQLPSGVPHSDVWFTAGRRACVAALGFAATNLEERWLLGLMQHGSPADVELEAIRVLMQEHRSSKPLYVYANSQSVVQGLQNRDVKDRRVGDMQLWQSVLQWVSANPGVLHVGDSRDGEELKWNRKVVERAQSIQAWVLSSHGQRVWEPSKHERQEIVALSHVGHVGVTKMLKRVWQVARWEGDREQVARWVQCCSCTRSPPQPQRTEGPWSRLQLAHVKDLPLSSKGYSSLLVLLDEFSGWVDAFPMRKGNREEMVTEMVTLLQEHVVQRLGMPSCISMGHCERFLQDAVQMSLQMVVDVQFLLPNWVEAITTSLQRLAQSAGKHWADSLSLIMAALRAMCVRSAVLGPYQLCSHRPLVLRLSPVEGEAPPDPTESLLPWLARLREDRAEYKQRVQEAMGV", "length": 885, "header": "tr|A0A8V0YDF4-1|A0A8V0YDF4_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN=LOC121110417 PE=3 SV=1 CANONICAL=A0A8V0YDF4-1" }, "locus": { "chromosome": "3", "start_pos": 104997970, "end_pos": 104995316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024660.1", "url": "https://www.ensembl.org/id/ENSGALT00010024660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013990.1", "url": "https://www.ensembl.org/id/ENSGALP00010013990.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 858, "start_aa": "Thr", "end_pos": 858, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr858", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA metabolic process", "id": "GO:0006259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF4" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 266, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 858 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 366, "end_pos": 368 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YDI6-1", "uniprot_ac": "A0A8V0YDI6", "uniprot_id": "A0A8V0YDI6_CHICK", "mass": { "chemical_mass": 53550.0, "monoisotopic_mass": 53550.0 }, "refseq": {}, "gene_names": [ { "name": "SLC37A3", "type": "recommended", "evidence": [ { "id": "A0A8V0YDI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6" } ] } ], "protein_names": [ { "name": "Sugar phosphate exchanger 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YDI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 37 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YDI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC37A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6", "locus": { "chromosome": "1", "start_pos": 56781331, "end_pos": 56816703, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013328", "url": "https://www.ensembl.org/id/ENSGALG00010013328" } ] } } ], "crossref": [ { "id": "A0A8V0YDI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17342", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17342", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDI6", "url": "https://www.orthodb.org/?gene=A0A8V0YDI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ72", "url": "https://www.orthodb.org/?gene=A0A8V0YJ72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43184:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43184:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YDI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPGSSRRQPSNRGLVSHCTHHHIVVFLLTFFSNVKVSISSQWTPSCLNSTTFELRPNELWNSNHLFPNAEEATLFLGTLDTIFLFSYAVGLFVSGIVGDRLNLRWVLSFGMCSSALVVFFFGTLTEWLHFYNKWFYCCLWVVNGLLQSTGWPCVVAVMGNWFGKAGRGFVFGLWSACASVGNILGAFLASCVLKYGYEYAFLVTASVQFAGGVIVFCGLLTSPKEVGLPELGADEEGSVEEDANRPLMGDDDADDDEGNYSIQAADTDSQPKAIGFFQACCLPGVVLYSLAYACLKLVNYSFFFWLPFYLSNNFGWKEAEADQLSIWYDVGGIIGGTIQGLISDVLQKRAPVLAISLLFAVGSLFGYSRSPNSKPINAVIMAITGFFIGGPSNMISSAISADLGRQDLVRGSSEALATVTGIVDGTGSIGAAVGQYLVSLIQENLGWMWVFYFFILMTSSTILFISPLIVREIRLLLHERRLRMLAE", "length": 489, "header": "tr|A0A8V0YDI6-1|A0A8V0YDI6_CHICK Isoform 1 of Sugar phosphate exchanger 3 OS=Gallus gallus OX=9031 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A8V0YDI6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI6/entry", "sequence": { "sequence": "MAVPGSSRRQPSNRGLVSHCTHHHIVVFLLTFFSNVKVSISSQWTPSCLNSTTFELRPNELWNSNHLFPNAEEATLFLGTLDTIFLFSYAVGLFVSGIVGDRLNLRWVLSFGMCSSALVVFFFGTLTEWLHFYNKWFYCCLWVVNGLLQSTGWPCVVAVMGNWFGKAGRGFVFGLWSACASVGNILGAFLASCVLKYGYEYAFLVTASVQFAGGVIVFCGLLTSPKEVGLPELGADEEGSVEEDANRPLMGDDDADDDEGNYSIQAADTDSQPKAIGFFQACCLPGVVLYSLAYACLKLVNYSFFFWLPFYLSNNFGWKEAEADQLSIWYDVGGIIGGTIQGLISDVLQKRAPVLAISLLFAVGSLFGYSRSPNSKPINAVIMAITGFFIGGPSNMISSAISADLGRQDLVRGSSEALATVTGIVDGTGSIGAAVGQYLVSLIQENLGWMWVFYFFILMTSSTILFISPLIVREIRLLLHERRLRMLAE", "length": 489, "header": "tr|A0A8V0YDI6-1|A0A8V0YDI6_CHICK Isoform 1 of Sugar phosphate exchanger 3 OS=Gallus gallus OX=9031 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A8V0YDI6-1" }, "locus": { "chromosome": "1", "start_pos": 56814261, "end_pos": 56797741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032071.1", "url": "https://www.ensembl.org/id/ENSGALT00010032071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018861.1", "url": "https://www.ensembl.org/id/ENSGALP00010018861.1" } ] } }, { "isoform_ac": "A0A8V0YJ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ72/entry", "sequence": { "sequence": "MAVPGSSRRQPSNRGLVSHCTHHHIVVFLLTFFSYSLLHASRKTFSNVKVSISSQWTPSCLNSTTFELRPNELWNSNHLFPNAEEATLFLGTLDTIFLFSYAVGLFVSGIVGDRLNLRWVLSFGMCSSALVVFFFGTLTEWLHFYNKWFYCCLWVVNGLLQSTGWPCVVAVMGNWFGKAGRGFVFGLWSACASVGNILGAFLASCVLKYGYEYAFLVTASVQFAGGVIVFCGLLTSPKEVGLPELGADEEGSVEEDANRPLMGDDDADDDEGNYSIQAADTDSQPKAIGFFQACCLPGVVLYSLAYACLKLVNYSFFFWLPFYLSNNFGWKEAEADQLSIWYDVGGIIGGTIQGLISDVLQKRAPVLAISLLFAVGSLFGYSRSPNSKPINAVIMAITGFFIGGPSNMISSAISADLGRQDLVRGSSEALATVTGIVDGTGSIGAAVGQLSRN", "length": 453, "header": "tr|A0A8V0YJ72-1|A0A8V0YJ72_CHICK Computationally mapped isoform of Sugar phosphate exchanger 3 OS=Gallus gallus OX=9031 GN=SLC37A3 PE=3 SV=1 CANONICAL=A0A8V0YDI6-1" }, "locus": { "chromosome": "1", "start_pos": 56814261, "end_pos": 56781801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032076.1", 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"evidence": [ { "id": "XP_004943334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943334" } ] } ], "protein_names": [ { "name": "Neutrophil cytosolic factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YDM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1/entry#names_and_taxonomy" } ] }, { "name": "neutrophil cytosol factor 2", "type": "synonym", "evidence": [ { "id": "XP_004943334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943334" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943334.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943334" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1", "locus": { "chromosome": "8", "start_pos": 7615659, "end_pos": 7623229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011503", "url": "https://www.ensembl.org/id/ENSGALG00010011503" } ] } } ], "crossref": [ { "id": "A0A8V0YDM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06406", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06406", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12046", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12046", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424445", "url": "https://www.ncbi.nlm.nih.gov/gene/424445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YATMEDW", "url": "https://omabrowser.org/oma/group/YATMEDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDM1", "url": "https://www.orthodb.org/?gene=A0A8V0YDM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1236973", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236973", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5668599", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943334", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVETIRLWQEGVCAADGKEWGAALKAFTAVQNPPAKICFNIGCTHLVLGQLAEAEEAFTQSISCDKHLAVAYFQRGTVFYKRHNHEMALKDFKEALAQLRGNQLIDYKILGLRYRLFACEILYNIALVYATMENWKKAEEHLTLAMSSKSEPQHNKIDRAMEAILKQKLYEPVAIPTGKLFRPNEKQVAQLEKKDYLGKAMVVASVVDKDSFSGFAPLQPQASGPPPRPKTPEILRALEGQPHRVLYEFIPETAEELQVLPGNIVFVLKKEKDNWATVMFNGKKGIVPCNFLEPMELQHKLHVQDEAPLEPDIPEPPSSTAPRPRRPAPDCVPVTSTQQREASKESEPDIPKPYVLKVHYKYTVAMQVKPDLSYKELLGLVCDKLELQPEHTMLRYKSAASGELVTLSAQNLEEAWSHSKDQCLTVWCDCTEGEGFLPDSKPEEPQQAAAETGPTQVVAQYSYEATQPEDLEFQAGDVILVLSKVNEDWLEGQCNGKIGIFPSAFVRDGNTKDP", "length": 516, "header": "tr|A0A8V0YDM1-1|A0A8V0YDM1_CHICK Isoform 1 of Neutrophil cytosolic factor 2 OS=Gallus gallus OX=9031 GN=NCF2 PE=3 SV=1 CANONICAL=A0A8V0YDM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1/entry", "sequence": { "sequence": "MSLVETIRLWQEGVCAADGKEWGAALKAFTAVQNPPAKICFNIGCTHLVLGQLAEAEEAFTQSISCDKHLAVAYFQRGTVFYKRHNHEMALKDFKEALAQLRGNQLIDYKILGLRYRLFACEILYNIALVYATMENWKKAEEHLTLAMSSKSEPQHNKIDRAMEAILKQKLYEPVAIPTGKLFRPNEKQVAQLEKKDYLGKAMVVASVVDKDSFSGFAPLQPQASGPPPRPKTPEILRALEGQPHRVLYEFIPETAEELQVLPGNIVFVLKKEKDNWATVMFNGKKGIVPCNFLEPMELQHKLHVQDEAPLEPDIPEPPSSTAPRPRRPAPDCVPVTSTQQREASKESEPDIPKPYVLKVHYKYTVAMQVKPDLSYKELLGLVCDKLELQPEHTMLRYKSAASGELVTLSAQNLEEAWSHSKDQCLTVWCDCTEGEGFLPDSKPEEPQQAAAETGPTQVVAQYSYEATQPEDLEFQAGDVILVLSKVNEDWLEGQCNGKIGIFPSAFVRDGNTKDP", "length": 516, "header": "tr|A0A8V0YDM1-1|A0A8V0YDM1_CHICK Isoform 1 of Neutrophil cytosolic factor 2 OS=Gallus gallus OX=9031 GN=NCF2 PE=3 SV=1 CANONICAL=A0A8V0YDM1-1" }, "locus": { "chromosome": "8", "start_pos": 7622827, "end_pos": 7615817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027543.1", "url": "https://www.ensembl.org/id/ENSGALT00010027543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015774.1", "url": "https://www.ensembl.org/id/ENSGALP00010015774.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424445", "resource": "KEGG Pathway" }, { "id": "R-GGA-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-GGA-1236973", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236973", "resource": "Reactome", "description": "Cross-presentation of particulate exogenous antigens (phagosomes)" }, { "id": "R-GGA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T2A3-1", "protein_name": "Neutrophil cytosol factor 2", "gene_name": "NCF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLAEAISLWNEGVLAADKKDWKGALDAFTGVQDPHSRICFNVGCIYTILGNLPEAEKAFTKSINRDKHLAVSYFQRGMLYYQMEKYDSAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEVLYNIAFMYAKREEWKKAEEHLALAVSMKSEPRHSKIDRAMESVWKQKLYEPVVIPVGRLFRPNEKQVAQLVKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEETSLESDIPAPPSSSAPGRPQLSPDSFCWLSQQEIKLSVPKSYTLKVHYKYTVVMETQFRLPYSQVRDMVAKKLDLLPEHTKLSYRRQDSNELVPLSEFSMKDAWAQVKNYCLTLWCENTVGDQGFPDEPEESKKSDANNQTTEPELKEGSKVVALFSYEATQPEDLEFLEGDVILVISTVNEEWLEGECKGKVGIFPKAFVEQHPTTDLESTPGRV", "length": 526 }, "evidence": [ { "id": "A0A8V0YDM1", "url": "https://omabrowser.org/oma/group/A0A8V0YDM1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O70145-1", "protein_name": "Neutrophil cytosol factor 2", "gene_name": "Ncf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLAEAIRLWNEGVLAADKKDWKGALEAFSEVQDPHSRICFNIGCVNTILENLQAAEQAFTKSINRDKHSAVAYFQRGMLYYRMEKYDLAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEVLYNIALMHAKKEEWKKAEEQLALATNMKSEPRHSKIDKAMESIWKQKLFEPVVIPVGRLFRPNERQVAQLAKKDYLGKATVVASVVHQDNFSGFAPLQPQSAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSPESDIPPPPNSSPPGRLQLSPGHKQKEPKELKLSVPMPYMLKVHYKYTVVMETRLGLPYSQLRNMVSKKLALSPEHTKLSYRRRDSHELLLLSEESMKDAWGQVKNYCLTLWCEHTVGDQGLIDEPIQRENSDASKQTTEPQPKEGTQVVAIFSYEAAQPEDLEFVEGDVILVLSHVNEEWLEGECKGKVGIFPKAFVEGCAAKNLEGIPREV", "length": 525 }, "evidence": [ { "id": "A0A8V0YDM1", "url": "https://omabrowser.org/oma/group/A0A8V0YDM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19878-1", "protein_name": "Neutrophil cytosol factor 2", "gene_name": "NCF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGKLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV", "length": 526 }, "evidence": [ { "id": "A0A8V0YDM1", "url": "https://omabrowser.org/oma/group/A0A8V0YDM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "NADPH oxidase complex", "id": "GO:0043020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "respiratory burst", "id": "GO:0045730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" }, { "name": "superoxide-generating NAD(P)H oxidase activity", "id": "GO:0016175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM1" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 299, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YEV7-1", "uniprot_ac": "A0A8V0YEV7", "uniprot_id": "A0A8V0YEV7_CHICK", "mass": { "chemical_mass": 81292.0, "monoisotopic_mass": 81292.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM23", "type": "recommended", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM23", "type": "recommended", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein ARD-1", "type": "synonym", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase TRIM23", "type": "synonym", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] }, { "name": "Tripartite motif-containing protein 23", "type": "synonym", "evidence": [ { "id": "A0A8V0YEV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase 1/TBK1 by facilitating its dimerization and ability to phosphorylate the selective autophagy receptor SQSTM1. In order to achieve this function, TRIM23 mediates 'Lys-27'-linked auto-ubiquitination of its ADP-ribosylation factor (ARF) domain to induce its GTPase activity and its recruitment to autophagosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7#function" }, { "database": "UniProtKB", "id": "ARBA00057906", "url": "https://www.uniprot.org/uniprotkb/ARBA00057906#function" }, { "database": "UniProtKB", "id": "A0A8V0YLS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7", "locus": { "chromosome": "Z", "start_pos": 21136806, "end_pos": 21158045, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012247", "url": "https://www.ensembl.org/id/ENSGALG00010012247" } ] } } ], "crossref": [ { "id": "A0A8V0YEV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04158", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04158", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16645", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16645", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427164", "url": "https://www.ncbi.nlm.nih.gov/gene/427164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDN6", "url": "https://www.orthodb.org/?gene=A0A8V0YDN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEV7", "url": "https://www.orthodb.org/?gene=A0A8V0YEV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLS4", "url": "https://www.orthodb.org/?gene=A0A8V0YLS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YDN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRPRDLAAATREEVRKRSAGGAGTSEPGNSCSRYAPSDTATARETTAPTGRCACGALRRRTVASRALLGRCLLGCVVLEGSPRRQSRGARRELQFFAVWSEEACAVLLLPLQRSACAHWDWRRCFPVDPLCSAPSKMAALVVNKAGAVPDSSRGASNSRGPTGAAVKVRRAACCLALSSLWPARAVMEVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAVRCPFDRQVTELGDSGVWGLKKNFALLELLERLQNGPPGQCGTAEEAIGLSGESIIRCDEDEAHVASVYCTVCATHLCADCSQLTHSTKTLAKHKRVPLADKPHEKTMCSQHQVHAIEFVCLEEDCQASPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGVGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTELADHVQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRVSEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRNWYIQGCDARSGTGLFEGLDWLSRQLVAAGVLDVA", "length": 736, "header": "tr|A0A8V0YEV7-1|A0A8V0YEV7_CHICK Isoform 1 of E3 ubiquitin-protein ligase TRIM23 OS=Gallus gallus OX=9031 GN=TRIM23 PE=3 SV=1 CANONICAL=A0A8V0YEV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN6/entry", "sequence": { "sequence": "MAALVVNKAGAVPDSSRGASNSRGPTGAAVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAVRCPFDRQVTELGDSGVWGLKKNFALLELLERLQNGPPGQCGTAEEAIGLSGESIIRCDEDEAHVASVYCTVCATHLCADCSQLTHSTKTLAKHKRVPLADKPHEKTMCSQHQVHAIEFVCLEEDCQASPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGVGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTELADHVQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIAVVFVVDSSHRDRVSEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRNWYIQGCDARSGTGLFEGLDWLSRQLVAAGVLDVA", "length": 541, "header": "tr|A0A8V0YDN6-1|A0A8V0YEV7_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM23 OS=Gallus gallus OX=9031 GN=TRIM23 PE=3 SV=1 CANONICAL=A0A8V0YEV7-1" }, "locus": { "chromosome": "Z", "start_pos": 21157435, "end_pos": 21139775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029345.1", "url": "https://www.ensembl.org/id/ENSGALT00010029345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017042.1", "url": "https://www.ensembl.org/id/ENSGALP00010017042.1" } ] } }, { "isoform_ac": "A0A8V0YEV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7/entry", "sequence": { "sequence": "MVRPRDLAAATREEVRKRSAGGAGTSEPGNSCSRYAPSDTATARETTAPTGRCACGALRRRTVASRALLGRCLLGCVVLEGSPRRQSRGARRELQFFAVWSEEACAVLLLPLQRSACAHWDWRRCFPVDPLCSAPSKMAALVVNKAGAVPDSSRGASNSRGPTGAAVKVRRAACCLALSSLWPARAVMEVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAVRCPFDRQVTELGDSGVWGLKKNFALLELLERLQNGPPGQCGTAEEAIGLSGESIIRCDEDEAHVASVYCTVCATHLCADCSQLTHSTKTLAKHKRVPLADKPHEKTMCSQHQVHAIEFVCLEEDCQASPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGVGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTELADHVQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRVSEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRNWYIQGCDARSGTGLFEGLDWLSRQLVAAGVLDVA", "length": 736, "header": "tr|A0A8V0YEV7-1|A0A8V0YEV7_CHICK Isoform 1 of E3 ubiquitin-protein ligase TRIM23 OS=Gallus gallus OX=9031 GN=TRIM23 PE=3 SV=1 CANONICAL=A0A8V0YEV7-1" }, "locus": { "chromosome": "Z", "start_pos": 21157846, "end_pos": 21139775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029351.1", "url": "https://www.ensembl.org/id/ENSGALT00010029351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017047.1", "url": "https://www.ensembl.org/id/ENSGALP00010017047.1" } ] } }, { "isoform_ac": "A0A8V0YLS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS4/entry", "sequence": { "sequence": "MAALVVNKAGAVPDSSRGASNSRGPTGAAVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAVRCPFDRQVTELGDSGVWGLKKNFALLELLERLQNGPPGQCGTAEEAIGLSGESIIRCDEDEAHVASVYCTVCATHLCADCSQLTHSTKTLAKHKRVPLADKPHEKTMCSQHQVHAIEFVCLEEDCQASPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGVGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRVSEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRNWYIQGCDARSGTGLFEGLDWLSRQLVAAGVLDVA", "length": 533, "header": "tr|A0A8V0YLS4-1|A0A8V0YLS4_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM23 OS=Gallus gallus OX=9031 GN=TRIM23 PE=3 SV=1 CANONICAL=A0A8V0YEV7-1" }, "locus": { "chromosome": "Z", "start_pos": 21157435, "end_pos": 21139775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029349.1", "url": "https://www.ensembl.org/id/ENSGALT00010029349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017045.1", "url": "https://www.ensembl.org/id/ENSGALP00010017045.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": 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"sequence": { "sequence": "MDLFGDLRRMNKRQVLNFAMIVSSALMIWKGLIVITGSESPIVVVLSGSMEPAFHRGDLLFLTNFHDDPIRAGEIVVFKVEGRDIPIVHRVIKIHEKENGNIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES", "length": 173, "header": "tr|A0A8V0YDP0-1|A0A8V0YDP0_CHICK Isoform 1 of Signal peptidase complex catalytic subunit SEC11 OS=Gallus gallus OX=9031 GN=SEC11C PE=1 SV=1 CANONICAL=A0A8V0YDP0-1" }, "locus": { "chromosome": "Z", "start_pos": 1233376, "end_pos": 1228489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024827.1", "url": "https://www.ensembl.org/id/ENSGALT00010024827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014077.1", "url": "https://www.ensembl.org/id/ENSGALP00010014077.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-422085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422085", "resource": "Reactome", "description": "Synthesis, secretion, and deacylation of Ghrelin" }, { "id": "R-GGA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ], "pmid": "" }, { "name": "signal peptidase activity", "id": "GO:0009003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "signal peptidase complex", "id": "GO:0005787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-422051", "name": "Cleavage of the signal peptide of Preproghrelin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [ "R-GGA-422044" ], "output_participant_list": [ "R-GGA-422090" ], "enzyme_list": [ "A0A8V0YDP0-1" ], "evidence": [ { "id": "R-GGA-422051", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422051" } ] }, { "id": "R-GGA-9932162", "name": "Removal of CDH1 signal peptide", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-GGA-9816039" ], "output_participant_list": [ "R-GGA-9932158" ], "enzyme_list": [ "A0A8V0YDP0-1" ], "evidence": [ { "id": "R-GGA-9932162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9932162" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-422044", "participant_name": "GHRL [endoplasmic reticulum lumen]", "crossref": [ { "id": "A0A8V0ZA18", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010019047", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010027486", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010046112", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-422090", "participant_name": "GHRL [endoplasmic reticulum lumen]", "crossref": [ { "id": "ENSGALP00010027486", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0ZA18", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010019047", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010046112", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9816039", "participant_name": "CDH1 [endoplasmic reticulum membrane]", "crossref": [ { "id": "A0A8V0Y995", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010014165", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010024941", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010010422", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9932158", "participant_name": "CDH1 [endoplasmic reticulum lumen]", "crossref": [ { "id": "ENSGALP00010014165", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010010422", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0Y995", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010024941", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YDP0", "gene_name": "SEC11C", "activity": [ { "ec_number": "3.4.21.89", "activity": "Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.", "evidence": [ { "id": "A0A8V0YDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ] }, { "ec_number": "3.4.21.89", "activity": "", "evidence": [ { "id": "A0A8V0YDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP0" }, { "id": "PF00717", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00717" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S24/S26A/S26B/S26C", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 120, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.89", "ec_name": "Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.", "evidence": [ { "id": "3.4.21.89", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.89" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"name": "E3 ubiquitin-protein ligase", "type": "recommended", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WWP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1", "locus": { "chromosome": "2", "start_pos": 122719898, "end_pos": 122659411, "strand": "-", "evidence": [ { "database": "Ensembl 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1253288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253288", "database": "Reactome", "categories": [ "Enzyme 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"MATASPRTDTSNNHNGRLQMQVTVSSAKLKRKKNWFGTTFYTELTADGEIKKTAKSSSSSNPKWDEQLTVNVTPQTTLEFRVWSHHTLKADALLGRATVDLRQALEIHNRKLDKVKEQLKLSLENKSGMVQTGELTVVLDGLVVEQESLTNLSSPATIEVQQNGEAVHENRDASARSTSRSACDVSNGNDNQVPSNSVVQNAFCIEAVNGNNSPSPTHIAARPKNTPVPKPLGAELVNSTVNGETSSSAPETGNSSVSEAMVGSEEAPMSTDCTNTTAEPQSTEEAASCSESHTSALSVASAGLEASTTTDCAQPNTSTAADAAKPRDSSSASSASGDPVRQQTVNAGTEPLPPGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSKFGMQLLYSLCVCLFVFSFSLERRVDSNDRVYFVNHNTKTTQWEDPRTQGLQNEDPLPEGWEIRYTREGVRYFVDHNTRTTTFNDPRTGKSSVNKGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKSNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECNLEMYFCVDMELLGKVTSHELKSGGSNILVTEENKEEYIGLMAEWRFSRGVREQTKAFLDGFNEVVPLQWLHYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "length": 925, "header": "tr|A0A8V0YDQ1-1|A0A8V0YDQ1_CHICK Isoform 1 of E3 ubiquitin-protein ligase OS=Gallus gallus OX=9031 GN=WWP1 PE=4 SV=1 CANONICAL=A0A8V0YDQ1-1" }, "locus": { "chromosome": "2", "start_pos": 122718548, "end_pos": 122682528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032150.1", "url": "https://www.ensembl.org/id/ENSGALT00010032150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018940.1", "url": "https://www.ensembl.org/id/ENSGALP00010018940.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1253288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253288", "resource": "Reactome", "description": "Downregulation of ERBB4 signaling" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1253282", "name": "ERBB4 ubiquitination by WWP1/ITCH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZZH3-1", "A0A8V0YDQ1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1253282", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253282" } ] }, { "id": "R-GGA-1253300", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZZH3-1", "A0A8V0YDQ1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1253300", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253300" } ] }, { "id": "R-GGA-2682349", "name": "RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-947590" ], "enzyme_list": [ "A0A8V0XFW1-1", "A0A8V1AHA8-1", "Q6U1I9-1", "A0A3Q2UC96-1", "A0A8V0ZFT3-1", "P05625-1", "A0A8V0YDQ1-1" ], "evidence": [ { "id": "R-GGA-2682349", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2682349" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-947590", "participant_name": "Pi [plasma membrane]", "crossref": [ { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { 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In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1#function" }, { "database": "UniProtKB", "id": "ARBA00056760", "url": "https://www.uniprot.org/uniprotkb/ARBA00056760#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WRNIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1", "locus": { "chromosome": "2", "start_pos": 67355777, "end_pos": 67330173, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011593", "url": "https://www.ensembl.org/id/ENSGALG00010011593" } ] } } ], "crossref": [ { "id": "A0A8V0YDY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18139", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18139", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008921", "database": 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"sequence": { "sequence": "MEGAEVQVRCPVCLRELPGALINSHLDRCLQAADGEAQRSCSPPSKRPRLASAQPGGEAEGQPVEARPEAAPVFSLFNKGQSPGAPGRRSGAGRGDAAEKPEEGGGPTLRGASVAQRLEGQPLADRLRPDTLRDYVGQERVLGAHTLLRSLLESHEIPSLILWGPPGCGKTTLAHIIANSSKKKGMRFVTLSATSAKTNDVRDVISQAQNEKRLFKRKTILFIDEIHRFNKSQQLFLLPSHTQDTFLPHVECGTVTLIGATTENPSFQVNAALLSRCRVIVLEKLSVEAMEAILLRAVKSLGVQVLGQGNQHSSSATGSSKESSELPVYVEEKALSTLAYLCDGDARTGLNGLQLAVQARLAAGKTTLLSFTEGCSVNGVLITEEHVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDENASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPLALTQAVAAYQGCHFIGMPECEVILAQCVVYFARAPKSIEVYRAYGNVKECLRMHTGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYKEPVEQDYLPEELKGTDFFKERRT", "length": 571, "header": "tr|A0A8V0YDY1-1|A0A8V0YDY1_CHICK Isoform 1 of ATPase WRNIP1 OS=Gallus gallus OX=9031 GN=WRNIP1 PE=3 SV=1 CANONICAL=A0A8V0YDY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1/entry", "sequence": { "sequence": "MEGAEVQVRCPVCLRELPGALINSHLDRCLQAADGEAQRSCSPPSKRPRLASAQPGGEAEGQPVEARPEAAPVFSLFNKGQSPGAPGRRSGAGRGDAAEKPEEGGGPTLRGASVAQRLEGQPLADRLRPDTLRDYVGQERVLGAHTLLRSLLESHEIPSLILWGPPGCGKTTLAHIIANSSKKKGMRFVTLSATSAKTNDVRDVISQAQNEKRLFKRKTILFIDEIHRFNKSQQLFLLPSHTQDTFLPHVECGTVTLIGATTENPSFQVNAALLSRCRVIVLEKLSVEAMEAILLRAVKSLGVQVLGQGNQHSSSATGSSKESSELPVYVEEKALSTLAYLCDGDARTGLNGLQLAVQARLAAGKTTLLSFTEGCSVNGVLITEEHVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDENASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPLALTQAVAAYQGCHFIGMPECEVILAQCVVYFARAPKSIEVYRAYGNVKECLRMHTGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYKEPVEQDYLPEELKGTDFFKERRT", "length": 571, "header": "tr|A0A8V0YDY1-1|A0A8V0YDY1_CHICK Isoform 1 of ATPase WRNIP1 OS=Gallus gallus OX=9031 GN=WRNIP1 PE=3 SV=1 CANONICAL=A0A8V0YDY1-1" }, "locus": { "chromosome": "2", "start_pos": 67355284, "end_pos": 67330423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027729.1", "url": "https://www.ensembl.org/id/ENSGALT00010027729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015894.1", "url": "https://www.ensembl.org/id/ENSGALP00010015894.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "DNA synthesis involved in DNA repair", "id": "GO:0000731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY1" } ], "pmid": "" } ] } ] }, 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"A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": 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{ "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": 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"gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { 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phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": 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} ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of 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"id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": 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"A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": 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"activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155100" } ] }, { "annotation": "Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. 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of Glutamate receptor OS=Gallus gallus OX=9031 GN=GRIK1 PE=3 SV=1 CANONICAL=A0A8V0YE44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE39/entry", "sequence": { "sequence": "MDFPPPEHPGGIFETVENEPVNIEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPTVDHKDAFYINLYPDYAAISRAVLDLVLYYNWKIVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDARPLLKEMKKGKEFYVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTLDLFALDLEPYRYSGVNMTGFRLLNIENPQVSSVIEKWSMERLQAPPKPETGLLDGMMTTEAALMYDAVYMVAVASQRASQMTVSSLQCHRHKPWRFGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKIGVWNSYSGLNMTDSNKDRSTNITDSLANRTLIVTTILEDPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYEVKLVSDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNSDIEQCLSFNAIMEELGISLKHQKKLKKRSRTKAKSSFTSILTCHQRRTLRKETIA", "length": 875, "header": "tr|A0A8V0YE39-1|A0A8V0YE44_CHICK Computationally mapped isoform of Glutamate receptor OS=Gallus gallus OX=9031 GN=GRIK1 PE=3 SV=1 CANONICAL=A0A8V0YE44-1" }, "locus": { "chromosome": "1", "start_pos": 104372116, "end_pos": 104254247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027820.1", "url": "https://www.ensembl.org/id/ENSGALT00010027820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015954.1", "url": "https://www.ensembl.org/id/ENSGALP00010015954.1" } ] } }, { "isoform_ac": "A0A8V0YE44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44/entry", "sequence": { "sequence": "MASAFGPRWPRRAAPGGGGGGGGGLLFVLLCASAGLPLSGQQVLRIGGIFETVENEPVNIEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPTVDHKDAFYINLYPDYAAISRAVLDLVLYYNWKIVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDARPLLKEMKKGKEFYVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTLDLFALDLEPYRYSGVNMTGFRLLNIENPQVSSVIEKWSMERLQAPPKPETGLLDGMMTTEAALMYDAVYMVAVASQRASQMTVSSLQCHRHKPWRFGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKAAGEVSNHLYKVWKKIGVWNSYSGLNMTDSNKDRSTNITDSLANRTLIVTTILEDPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYEVKLVSDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNSDIEQCLSFNAIMEELGISLKHQKKLKKRSRTKAKSSFTSILTCHQRRTLRKETIA", "length": 927, "header": "tr|A0A8V0YE44-1|A0A8V0YE44_CHICK Isoform 1 of Glutamate receptor OS=Gallus gallus OX=9031 GN=GRIK1 PE=3 SV=1 CANONICAL=A0A8V0YE44-1" }, "locus": { "chromosome": "1", "start_pos": 104415159, "end_pos": 104254247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027829.1", "url": "https://www.ensembl.org/id/ENSGALT00010027829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015959.1", "url": "https://www.ensembl.org/id/ENSGALP00010015959.1" } ] } }, { "isoform_ac": "A0A8V0YIT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT1/entry", "sequence": { "sequence": "MASAFGPRWPRRAAPGGGGGGGGGLLFVLLCASAGLPLSGQQVLRIGGIFETVENEPVNIEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPTVDHKDAFYINLYPDYAAISRAVLDLVLYYNWKIVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDARPLLKEMKKGKEFYVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTLDLFALDLEPYRYSGVNMTGFRLLNIENPQVSSVIEKWSMERLQAPPKPETGLLDGMMTTEAALMYDAVYMVAVASQRASQMTVSSLQCHRHKPWRFGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKIGVWNSYSGLNMTDSNKDRSTNITDSLANRTLIVTTILEDPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYEVKLVSDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNSDIEQAFCFFYGLQCKQTHPSNSTSGTTLSTELDCGKLIREERGIRTQPSIHTV", "length": 910, "header": "tr|A0A8V0YIT1-1|A0A8V0YIT1_CHICK Computationally mapped isoform of Glutamate receptor OS=Gallus gallus OX=9031 GN=GRIK1 PE=3 SV=1 CANONICAL=A0A8V0YE44-1" }, "locus": { "chromosome": "1", "start_pos": 104415159, "end_pos": 104262222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027825.1", "url": "https://www.ensembl.org/id/ENSGALT00010027825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015957.1", "url": "https://www.ensembl.org/id/ENSGALP00010015957.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418489", "resource": "KEGG Pathway" }, { "id": "R-GGA-451307", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-451307", "resource": "Reactome", "description": "Activation of Na-permeable kainate receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "P22756-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "Grik1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERSTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRKLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPCALGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEAYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKESLGVEKCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA", "length": 949 }, "evidence": [ { "id": "A0A8V0YE44", "url": "https://omabrowser.org/oma/group/A0A8V0YE44/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39086-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "GRIK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTDLECGKLIREERGIRKQSSVHTV", "length": 918 }, "evidence": [ { "id": "A0A8V0YE44", "url": "https://omabrowser.org/oma/group/A0A8V0YE44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60934-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "Grik1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERGTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGVMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQPSALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRLRFYFRNKVRFHGSKTESLGVEKCLSFNAIMEELGISLKNQKKIKKKSRTKGKSSFTSILTCHQRRTQRKETVA", "length": 836 }, "evidence": [ { "id": "A0A8V0YE44", "url": "https://omabrowser.org/oma/group/A0A8V0YE44/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SDQ4-1", "protein_name": "Glutamate receptor 3.7", "gene_name": "GLR3.7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGLGIDPSVAITALIVVILVVPMDCQRPQLVNIGAVFAFDSVIGRAAKVALEAAVSDVNNDKSFLKETELRLLMEDSACNVFRGSFGAFELLEKEVVAMIGPISSSVAHTISDIAKGLHFPLVSFAATDPTLSALQFPFFLRTTPNDAHQMSALVDLINFYGWKEVISVYSDDELGRNGVSALDDELYKKRSRISYKVPLSVHSDEKFLTNALNKSKSIGPRVYILHFGPDPLLRIFDIAQKLQMMTHEYVWLATDWLSVTLDSLSDKGTLKRLEGVVGLRQHIPESVKMEHFTHKLQSNRSMNAYALHAYDTVWMIAHGIEELLNEGINITFSYSEKLLHARGTKLHLEKIKFFNSGELLLEKLLKVNFTGIAGQVQFGSGRNVIGCDYEIINVNKTDVHTVGFWSKNGGFSVVAPKTRHSQKKTSFVSDEKLGDITWPGGGREKPRGWVIADSADPLKIVVPRRVSFVEFVTEEKNSSHRIQGFCIDVFIEALKFVPYSVPYIFEPFGNGHSSPNYNHLIQMVTDGVYDAAVGDIAIVPSRSKLVDFSQPYASTGLVVVIPANDDNATWIFLRPFTSRLWCVVLVSFLVIAVVIWILEHRINEDFRGPPRRQLSTMLLFSFSTLFKRNQEDTISNLARLVMIVWLFLLMVLTASYTANLTSILTVQQLPSAITGIDSLRASEVPIGYQAGTFTLEYLTYSLGMARSRLVPLDSTEEYEKALKLGPTNWGGVAAIVDELPYIELFLAERTGFKIVGEPFMHRGWGFAFKRDSPLAIDMSTAILKLSETRKLQEIRKKWLCKTNCAGKSNWNPEPNQLHLKSFKGLYLVCIAITVSAFLVFVLRMIRQFVRYRRMERTSSMPRASWSASPTLRLRELVFDFVEFVDEKEEAIKRMFRRSDDSNNNPSHVGEVQADTEVPRN", "length": 921 }, "evidence": [ { "id": "A0A8V0YE44", "url": "https://omabrowser.org/oma/group/A0A8V0YE44/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "kainate selective glutamate receptor activity", "id": "GO:0015277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "kainate selective glutamate receptor complex", "id": "GO:0032983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" }, { "id": "SM00079", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ionotropic glutamate receptor C-terminal", "eco_id": "ECO_0000259", "start_pos": 455, "end_pos": 823, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE44" }, { "id": "SM00918", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ionotropic glutamate receptor L-glutamate and glycine-binding", "eco_id": "ECO_0000259", "start_pos": 465, "end_pos": 529, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YE45-1", "uniprot_ac": "A0A8V0YE45", "uniprot_id": "A0A8V0YE45_CHICK", "mass": { "chemical_mass": 310531.0, "monoisotopic_mass": 310531.0 }, "refseq": { "ac": "NP_001001754", "name": "cHz-cadherin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" }, "gene_names": [ { "name": "LOC414835", "type": "recommended", "evidence": [ { "id": "A0A8V0YE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ] }, { "name": "LOC414835", "type": "synonym", "evidence": [ { "id": "NP_001001754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" } ] } ], "protein_names": [ { "name": "Neural-cadherin", "type": "recommended", "evidence": [ { "id": "A0A8V0YE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45/entry#names_and_taxonomy" } ] }, { "name": "cHz-cadherin precursor", "type": "synonym", "evidence": [ { "id": "NP_001001754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY312363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992528 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Dec 10, 2021 this sequence version replaced NP_001001754.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" } ] }, { "annotation": "A chicken Hz-cadherin (cHz-cadherin) expressed in horizontal cells of the neural retina.", "evidence": [ { "database": "RefSeq", "id": "NP_001001754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" }, { "database": "PubMed", "id": "15042713", "url": "https://glygen.org/publication/PubMed/15042713" } ] }, { "annotation": "Cadherins are calcium-dependent cell adhesion proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45#function" }, { "database": "UniProtKB", "id": "RU004357", "url": "https://www.uniprot.org/uniprotkb/RU004357#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC414835", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45", "locus": {} } ], "crossref": [ { "id": "cd00053", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00053", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414835", "url": "https://www.ncbi.nlm.nih.gov/gene/414835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:414835", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYHTSQK", "url": "https://omabrowser.org/oma/group/PYHTSQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE45", "url": "https://www.orthodb.org/?gene=A0A8V0YE45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001001754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAGGLLLALPLLCGAAAGLGAPRLLRFSGHVPEDSPAGTRVRGVRVPLRGPGEPPARWALRGDGAHHFSLQRRPGGERGALEARTARRLDRGARAEYRLLLRAAVRPRAALLRVRVLARDDRRPRLPPAARLEPSPRGSELARLRSSDGEESPEVPLAYRARPALSADSLPASRRLSLWVWARDRGRPRRLLPAVRGPGEERRRRRPRSLSPGPRRYAARLPPGARVGDTVFTLPRGRDAGGWFELAAPGAAPLGVDRASGRLYLRRELPAGGGAEALVKVHRGGGRDDDWYLCHVTLLAPEEELLSWAMYPYPYLARVDPDARKGTLVYRLAARYSNSENTSAGVSYTLIAGGEERFQVDVDTGIIVTTGLPLVWNKEYVVTVQASDEYGNKSPFASISILVGSRPPQFTNMSYSVFVPENTPPGEKVAVVEAVSFQSQPLSYSLLTNPSGLFTVRQESGELLLTHPVDYEGEHHLYHLLLKAVEAESALSSVAEVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQSTDFSITRHGVISSNQRLNFERANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAGPSTLVATVRAKDPDGDGVLYLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVLENQPPGMYVLQVEAYDADLGVNGEVKYGLMHRDGASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTATDQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSMLAHQVQYFQINPSTGWVYVNHRISQTTRISHYIVATDGGNRSSTVELTVTITNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKATSPLGDPRVTYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFILKDASEDYQFFTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGQPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLIIINVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTNAVLTYRIIQNVQNEINLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTATILVTDVNDHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDRKFSIETDKGNNCGFIRLRKQIDFEKPHERVFNLTLKAEDMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNKSDPGGQFSVASDGWVIVAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAHYNPVVWENTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTALHTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILPTTVLGQVLAPDEDDWDRKIYQFEGKTSRYFILNDNSGLLTIKEGTPPGTYNIKVRVIDGVWPDVVSTVKVIVKEIKDDALHNAGSLQIKDTTPEEFISQFPEKESKYNQLKKLLSEIISVQLENVHIFSVLKSSQTRGVDVWFAVYGPPYYKAEKLNGNVAASRAWLENILDINITQIGIDECVTANCTHSSGCISKYEHSHVPTITTAGSISLVSVTVLSSALCSCAARESPHLSCSSYQTNPCLNGGTCVDTDLGYRCRCSANFHGPDCQQTKHSFKGHGYAWFPPLKPCFESRISLEFITEVADGLLLYQGPVARGQPGQLEDFIALELSGGVPALTVSHSSGELFLQLSKKVNVADRRWHNIKIKSDGKKVKLVLDHCTNGSVRHSGSVDKKISQVDLSACEASEETMGTWSMSRIFSGHQPLQLGGVKKILPYRDSQKRFRGFVGCIRNVVVDTKVYDLEHPAESLNSSPGCILTDEMCQSAGMVSCGVHGRCVGDWGFFHCDCAPGYAGPACDKVLPEWAFGRDSWIHYEPRNTLSTLSTRIQLMVRTRISRSTLLSLASADGSSFIRLEVDEGYFCVNFSLGGKSHSLRMKTLRINNGQWVLLTMERYNNEFTLRVNSGGGDQEVTSVLGTDRWFEMDWASVVLGNRLPSHSESDFQGCLRDVQLNGQPLLVEGRSTEFGFVLRRQGVTMGCHSSACSSHPCYSPFLCVDLWRKYECRCPAGKVEVTDNLTGLRHCSSSPCGHWTCRNGGTCVAQSQHKTICQCPEGYKGRWCEISQVKAGRPVGLSSGSILAISMCLLVFLALLVSYTVWSQWGSSGFRKGGIYHIPEERESWEDVRENVFNYNEEGGGEHDQNAYNVAELKKPLRSIPHFSLRATFPRSRTPTRPKRGSVPNRAQQKQSTSAVSSVPDFKEYVSQIIQDADNDLQNPPADTVHFYCLEGECSLAGSLSSLNSISGDEDLNYDCLQEWGSKFDKLKELYEPSHGHL", "length": 2819, "header": "tr|A0A8V0YE45-1|A0A8V0YE45_CHICK Isoform 1 of Neural-cadherin OS=Gallus gallus OX=9031 GN=LOC414835 PE=4 SV=1 CANONICAL=A0A8V0YE45-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45/entry", "sequence": { "sequence": "MLGAGGLLLALPLLCGAAAGLGAPRLLRFSGHVPEDSPAGTRVRGVRVPLRGPGEPPARWALRGDGAHHFSLQRRPGGERGALEARTARRLDRGARAEYRLLLRAAVRPRAALLRVRVLARDDRRPRLPPAARLEPSPRGSELARLRSSDGEESPEVPLAYRARPALSADSLPASRRLSLWVWARDRGRPRRLLPAVRGPGEERRRRRPRSLSPGPRRYAARLPPGARVGDTVFTLPRGRDAGGWFELAAPGAAPLGVDRASGRLYLRRELPAGGGAEALVKVHRGGGRDDDWYLCHVTLLAPEEELLSWAMYPYPYLARVDPDARKGTLVYRLAARYSNSENTSAGVSYTLIAGGEERFQVDVDTGIIVTTGLPLVWNKEYVVTVQASDEYGNKSPFASISILVGSRPPQFTNMSYSVFVPENTPPGEKVAVVEAVSFQSQPLSYSLLTNPSGLFTVRQESGELLLTHPVDYEGEHHLYHLLLKAVEAESALSSVAEVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQSTDFSITRHGVISSNQRLNFERANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAGPSTLVATVRAKDPDGDGVLYLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVLENQPPGMYVLQVEAYDADLGVNGEVKYGLMHRDGASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTATDQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSMLAHQVQYFQINPSTGWVYVNHRISQTTRISHYIVATDGGNRSSTVELTVTITNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKATSPLGDPRVTYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFILKDASEDYQFFTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGQPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLIIINVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTNAVLTYRIIQNVQNEINLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTATILVTDVNDHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDRKFSIETDKGNNCGFIRLRKQIDFEKPHERVFNLTLKAEDMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNKSDPGGQFSVASDGWVIVAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAHYNPVVWENTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTALHTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILPTTVLGQVLAPDEDDWDRKIYQFEGKTSRYFILNDNSGLLTIKEGTPPGTYNIKVRVIDGVWPDVVSTVKVIVKEIKDDALHNAGSLQIKDTTPEEFISQFPEKESKYNQLKKLLSEIISVQLENVHIFSVLKSSQTRGVDVWFAVYGPPYYKAEKLNGNVAASRAWLENILDINITQIGIDECVTANCTHSSGCISKYEHSHVPTITTAGSISLVSVTVLSSALCSCAARESPHLSCSSYQTNPCLNGGTCVDTDLGYRCRCSANFHGPDCQQTKHSFKGHGYAWFPPLKPCFESRISLEFITEVADGLLLYQGPVARGQPGQLEDFIALELSGGVPALTVSHSSGELFLQLSKKVNVADRRWHNIKIKSDGKKVKLVLDHCTNGSVRHSGSVDKKISQVDLSACEASEETMGTWSMSRIFSGHQPLQLGGVKKILPYRDSQKRFRGFVGCIRNVVVDTKVYDLEHPAESLNSSPGCILTDEMCQSAGMVSCGVHGRCVGDWGFFHCDCAPGYAGPACDKVLPEWAFGRDSWIHYEPRNTLSTLSTRIQLMVRTRISRSTLLSLASADGSSFIRLEVDEGYFCVNFSLGGKSHSLRMKTLRINNGQWVLLTMERYNNEFTLRVNSGGGDQEVTSVLGTDRWFEMDWASVVLGNRLPSHSESDFQGCLRDVQLNGQPLLVEGRSTEFGFVLRRQGVTMGCHSSACSSHPCYSPFLCVDLWRKYECRCPAGKVEVTDNLTGLRHCSSSPCGHWTCRNGGTCVAQSQHKTICQCPEGYKGRWCEISQVKAGRPVGLSSGSILAISMCLLVFLALLVSYTVWSQWGSSGFRKGGIYHIPEERESWEDVRENVFNYNEEGGGEHDQNAYNVAELKKPLRSIPHFSLRATFPRSRTPTRPKRGSVPNRAQQKQSTSAVSSVPDFKEYVSQIIQDADNDLQNPPADTVHFYCLEGECSLAGSLSSLNSISGDEDLNYDCLQEWGSKFDKLKELYEPSHGHL", "length": 2819, "header": "tr|A0A8V0YE45-1|A0A8V0YE45_CHICK Isoform 1 of Neural-cadherin OS=Gallus gallus OX=9031 GN=LOC414835 PE=4 SV=1 CANONICAL=A0A8V0YE45-1" }, "locus": { "chromosome": "2", "start_pos": 125938725, "end_pos": 125895633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029576.1", "url": "https://www.ensembl.org/id/ENSGALT00010029576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017199.1", "url": "https://www.ensembl.org/id/ENSGALP00010017199.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 700, "start_aa": "Thr", "end_pos": 700, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr700", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Identification of a nonchordate-type classic cadherin in vertebrates: chicken Hz-cadherin is expressed in horizontal cells of the neural retina and contains a nonchordate-specific domain complex.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2004-04", "authors": "Tanabe Koji, Takeichi Masatoshi, Nakagawa Shinichi", "evidence": [ { "database": "RefSeq", "id": "NP_001001754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001754" } ], "reference": [ { "type": "PubMed", "id": "15042713", "url": "https://glygen.org/publication/PubMed/15042713" } ] } ], "pathway": [ { "id": "gga:414835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IM59-1", "protein_name": "Neural-cadherin isoform X1", "gene_name": "si:dkey-22o22.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRAHLRNPTFCRFLTACLLIILLAFANADSTLFYGHVEESALPGTVVAGFTFPLGDKCKEDNLAGLKTVLTGDDSLDFSLEYLGNKGFVLKTTETFATDSKLSYTVSARLPRCNGTTEEVTVKIKMLQKDDETRRFNESSVSTGVIGVKSGSRKPRAVSEEVSYTVTVSEDVKVGDLIFTVPDQKFEKKWFEVVSEGNSPIQMERDSGRVYLAHRLVSATEVMVKIHNMRGDEWYLCRLTLTLPNMSNLQWAMFPYPYLAAVGPDTGAGSVVYKLVAQSPDGSVGTAHFLLVDGGEDSFEVDQTTGEVKTTGRPLTPSKEYTLTVQAVDSQGRRGTHASLFILAGFRPPQFTNTTYTIHIPESSAVGQAVAVVQAISFQRKTLSYMLLVNPSNLFSINQESGALSLTRTVDYESGQHLHHLQVRASEPDTGLSNMAEVVVHITDENDCTPEFMHSIYSRDNVPETTPTGTSLLQVLARDCDTGLNAELSYFIQSVDFDITSQGVVSPSQRLDYERPNHMYECTVVAVDKGTPPRTGTASIRIRMANVNDEAPVFSQTIYKTFLSEDAGPETLVAIVHAKDPDGDGVTYAITGGNEDSNFELDNQKGIIKLRRSPPPRLRGPQYVLNVTATDDNAAGGALPLSSCAQVIVGINDINNNKPVFDECHNYSVNALVLENQPPGTFVLRVQAHDADTGVNGEVKYGIMQRDGASPGFTINPDTGVISTAVSFDREKQREYTLSVTATDQAQEPLIGICQITVLIADQNDNDPKFENSRYQYFLREDTPVGTSFLRAAAHDDDQGTNSAITYSLSQQNPAYFHINPSTGWIYVNQPISQTSRISQQIIATDGGSRSSSVDLTVIITNVHNQPPQWEQAEYWVTIPENTPRDTKIVTIKATSPLGDPRVTYNLEEGQVPETNMPVRFYIKPNRRDGSASILVAENLDYETTGFFTLRVRVQNVAAVPLASFTTVYVNITDVNDNVPFFMSSTYEATVPEGAEIGTSVAQVSATDLDSGLHGMINYIILKDQSGDSQFFSINSYTGIIHTRATFDREQKGSYLIEVQSQDSSESARPGQQGQPNTDTAYVRVFVTDVNDNAPAFSQPVYEISVEEDKEVGFVVITVTANDEDEGANAKLRYQITSGNTMGTFDVEPEVGTIFIAQRLDYEQVQRYELRLVASDGKWENQTMVVINVINQNDEAPLFTQTEYHASVMEELTELPVLVLEVSATDPDQEADQRAVRYSLHGQGAGSEFTIDEINGRIFAQRRLDREVRSAWQFLVLATDENGAGLTGFADVLVDVQDINDNAPVFLCATDNCFLGHVPENSPADTSIMEMRATDLDDPKAGKNAILTYRIVQNVRNEINLNLFSINPTTGTIYTVLRSLDREVVDRYLVVVEARDGGGLSGTGTATIVISDVNDHPPVFTQRVYMASMSENLDINSEVMVVAATDGDEGENSVMTFSIIGGDEDRKFFIETDKVNRRGIVRLKKKIDFEKPHERTFNLTVKVEDADFFSLAYCIIQVEDSNDHTPVFFPQFYEAGSMFEDVPVGTIVAQVTAMDLDSGQNGRFTYSIAPESDPFQQFLVDKSGWVVVADSLDREKVAQHRLMILATDMGSPALTGSAIVLVTVQDVNDNGPEFEAPYRPIVWENTIAPQVIHMNDTSTLLHAIDRDTSSNGGPFSIRLLMLTSDVTNFNLTDMRNGSAMITALRSFDREQQKQYLLPILMIDSGSPPMSSTSTLTVIIGDKNDHPHAPGHSEFIVYNIQGTLPTTVLGQVQSPDLDDWSEKVYKFEGKPPRQFILNQNNGQLSVREGTAAGLYSLQVRVADKSWPDVTSSAEVTVMELQEEALRNAASIRLANLTANEFFRASANEESRYMRLRRLLSELFQTDVENVDVFSLASGRQPAQHHLSVWFAAHGSPYYKPEKLHGYIAMHKAKLESALGVTILQVGVDECVYAACGQTGGCSSKVTFSDTPTTLNNGNISLVSVSAKASVQCGCLGRESVHLHCSSYSQSPCLNGGTCVDSELGYRCKCPPMFDGPECQQTKHSFLGNGYAWFHPIKPCFQSHISLEFITEAANGLLFYNGPMGAPQPREKEDFIALELKNGVPVLSVNHGSGTLTLQLSARATVTDRRWHHLDIISDGKSVQMILDHCSGAVVNEVEGLGVEMFETDQSVCKASGETPGSERFLDVYQPLQLGGVKETHSLRRSHPHYKGFVGCMRNLVVDSQVYDLSSAAESENTAPGCALTDGVCLTAGGPSCGVHGRCLGEWGSFSCDCHPGYSGHKCDKALPEWSFERDSVLRYQLRGGGSPRRTQAHFLLRTRSSTGTLLSMASRDANEFIILEIVDGYLNVRANLGDGTHSLKLTGQRVNHGQWVLISILRHDNIFILRLEQGGGSREVTGVLGQKKEIVVHPSSVFLGNSASPNTQGDFQGCMRDVRLNGHSLSLDGQSTEFSTVLERRGVVPGCHSDACSAKPCLSPLYCVDMWRKHECRCPANQVAVLDEVTGLMRCAPSPCSASTCRNGGTCLAHSTKSYQCRCPEGFRGQWCEIGQLKSLRLAALSPSSILAISMCLLVFFAVLVAVTVWNQKGSRNKFRKRGVYHIPAEHESWEDIRENILNYNEEGGGEQDQNAYDITELKRPLCSSLSQSSSCTTAPLIKSSQGSQEEVHPCGAIQNAAMLPYQHHSGGHCSMDFKSYVSRIIWEADNDSLSFPMDTYHVYCIEGSGSNAGSLSSLGSFISDDGFSYDTLRRWGSKFEGLSELYRRPELDIPYMDTVQSQSLEQQQ", "length": 2780 }, "evidence": [ { "id": "A0A8V0YE45", "url": "https://omabrowser.org/oma/group/A0A8V0YE45/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15943-1", "protein_name": "Neural-cadherin", "gene_name": "CadN", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAARRCLNQLRQRYITNRFNICTCAIFLISLPFILAIEETTFAGLSAENAARMLAGSPGDVEKSSLSHHSEMSLVLPHDTYPGFSIKKFKTHPVKINGSSHSGAAAYHMLDTDYSKYFTVLEDGVVMTTADISPLVNRPVQLVVVEQTPNATNTHNLQLFVMHRNDMLRFSGSLLDASGEVRENQPAGTRVRGVPLMQAFSGSILDEELATPKKVRYTIIDGNVDDAFALQERKANKNIQISAKSLVINGDDESGVWLVTNRPLDREERAHYDLSVEASDVDGLDRTVSKIQITVLDENDNRPIFKSLDYKFAIAGQKSASMESNSSVTYQRFAIMGKVEATDADGDKIAYRLKSPSNVVIIVPQTGEIMLAGEPTSNELLIEVIAHDLRYPSLVSAKPAKVLLEFLAAEPVSFIMQHLEHDDINNHSHHREKRRVTRAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVETNGAVRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFINRPLPMQAVVQLNAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGGRFEVDERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPSYEAEIPENQKKDSDIISIKAKSFADREIRYTLKAQGQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVTATEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVSDDHFAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKDGDNVRFGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEYFEIQAESGWIVLKKPLDRETYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWDHTVYGPIYVKENMPVGGKVVSIKASSGIEGNPTVFYRLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTKFIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEITSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDNLKENYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDINDMPPQFTKDEWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQNGSVTIQRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAPKFLKDYRPVLPEHVPPRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQDQKGANGDGMAVISSLRSFDREQQKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQPGSKDIFVYNYQGQSPDTPIGRVYVYDLDDWDLPDKKFYWEAMEHPRFKLDEDSGMVTMRAGTREGRYHLRFKVYDRKHTQTDIPANVTVTVREIPHEAVVNSGSVRLSGISDEDFIRVWNYRTQSMSRSKMDRFRDKLADLLNTERENVDIFSVQLKRKHPPLTDVRFSAHGSPYYKPVRLNGIVLMHREEIEKDVGINITMVGIDECLYENQMCEGSCTNSLEISPLPYMVNANKTALVGVRVDTIADCTCGARNFTKPESCRTTPCHNGGRCVDTRFGPHCSCPVGYTGPRCQQTTRSFRGNGWAWYPPLEMCDESHLSLEFITRKPDGLIIYNGPIVPPERDETLISDFIALELERGYPRLLIDFGSGTLELRVKTKKTLDDGEWHRIDLFWDTESIRMVVDFCKSAEIAEMEDGTPPEFDDMSCQARGQIPPFNEYLNVNAPLQVGGLYREQFDQSLYFWHYMPTAKGFDGCIRNLVHNSKLYDLAHPGLSRNSVAGCPQTEEVCAQTETTARCWEHGNCVGSLSEARCHCRPGWTGPACNIPTIPTTFKAQSYVKYALSFEPDRFSTQVQLRFRTREEYGELFRVSDQHNREYGILEIKDGHLHFRYNLNSLRTEEKDLWLNAIVVNDGQWHVVKVNRYGSAATLELDGGEGRRYNETFEFVGHQWLLVDKQEGVYAGGKAEYTGVRTFEVYADYQKSCLDDIRLEGKHLPLPPAMNGTQWGQATMARNLEKGCPSNKPCSNVICPDPFECVDLWNVYECTCGEGRIMSPDSKGCMDRNECLDMPCMNGATCINLEPRLRYRCICPDGFWGENCELVQEGQTLKLSMGALAAILVCLLIILILVLVFVVYNRRREAHIKYPGPDDDVRENIINYDDEGGGEDDMTAFDITPLQIPIGGPMPPELAPMKMPIMYPVMTLMPGQEPNVGMFIEEHKKRADGDPNAPPFDDLRNYAYEGGGSTAGSLSSLASGTDDEQQEYDYLGAWGPRFDKLANMYGPEAPNPHNTELEL", "length": 3097 }, "evidence": [ { "id": "A0A8V0YE45", "url": "https://omabrowser.org/oma/group/A0A8V0YE45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE45" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07445", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07445", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857733", "url": "https://www.ncbi.nlm.nih.gov/gene/100857733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857733", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCLMPDQ", "url": "https://omabrowser.org/oma/group/TCLMPDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE77", "url": "https://www.orthodb.org/?gene=A0A8V0YE77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEA8", "url": "https://www.orthodb.org/?gene=A0A8V0YEA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMH7", "url": "https://www.orthodb.org/?gene=A0A8V0YMH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMI1", "url": "https://www.orthodb.org/?gene=A0A8V0YMI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMI6", "url": "https://www.orthodb.org/?gene=A0A8V0YMI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSH7", "url": "https://www.orthodb.org/?gene=A0A8V0YSH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSI2", "url": "https://www.orthodb.org/?gene=A0A8V0YSI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140976", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQTLCQEGDQRCTSCPDPCGTSLCEMRNSQTNCSQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1130, "header": "tr|A0A8V0YE77-1|A0A8V0YE77_CHICK Isoform 1 of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQTLCQEGDQRCTSCPDPCGTSLCEMRNSQTNCSQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1130, "header": "tr|A0A8V0YE77-1|A0A8V0YE77_CHICK Isoform 1 of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032345.1", "url": "https://www.ensembl.org/id/ENSGALT00010032345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019123.1", "url": "https://www.ensembl.org/id/ENSGALP00010019123.1" } ] } }, { "isoform_ac": "A0A8V0YEA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA8/entry", "sequence": { "sequence": "MSVICNFPEDVEFAGGSYRITVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQTLCQEGDQRCTSCPDPCGTSLCEMRNSQTNCSQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1126, "header": "tr|A0A8V0YEA8-1|A0A8V0YEA8_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66165958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032384.1", "url": "https://www.ensembl.org/id/ENSGALT00010032384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019153.1", "url": "https://www.ensembl.org/id/ENSGALP00010019153.1" } ] } }, { "isoform_ac": "A0A8V0YMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH7/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1097, "header": "tr|A0A8V0YMH7-1|A0A8V0YMH7_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032355.1", "url": "https://www.ensembl.org/id/ENSGALT00010032355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019131.1", "url": "https://www.ensembl.org/id/ENSGALP00010019131.1" } ] } }, { "isoform_ac": "A0A8V0YMI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI1/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQTLCQEGDQRCTSCPDPCGTSLCEMRNSQTNCSQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1092, "header": "tr|A0A8V0YMI1-1|A0A8V0YMI1_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032362.1", "url": "https://www.ensembl.org/id/ENSGALT00010032362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019136.1", "url": "https://www.ensembl.org/id/ENSGALP00010019136.1" } ] } }, { "isoform_ac": "A0A8V0YMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI6/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCCQCEPITLELCMNLPYNYTSYPNYLGHRTQKEASVSWESSLFPALVQTNCYKYLMFFACTVLVPKCDPHTNQRIPPCRTLCVQSKERCESVLGIVGLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1058, "header": "tr|A0A8V0YMI6-1|A0A8V0YMI6_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=4 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032369.1", "url": "https://www.ensembl.org/id/ENSGALT00010032369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019141.1", "url": "https://www.ensembl.org/id/ENSGALP00010019141.1" } ] } }, { "isoform_ac": "A0A8V0YSH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH7/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSESQTLCQEGDQRCTSCPDPCGTSLCEMRNSQTNCSLQWPEDTDCTQFPDENSDNQTCLTPDEDVEECSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 1035, "header": "tr|A0A8V0YSH7-1|A0A8V0YE77_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032374.1", "url": "https://www.ensembl.org/id/ENSGALT00010032374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019144.1", "url": "https://www.ensembl.org/id/ENSGALP00010019144.1" } ] } }, { "isoform_ac": "A0A8V0YSI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSI2/entry", "sequence": { "sequence": "MLSMQQFPALPAEEERYRQVLSARRVLGTDEDNVGDGCSQKLASAKFLRLLLLILIPCICALILLLVILLTFVGVLEKTCFYSNGSEVLTVNGDIETSSILLPNMVENDSKTNPTVGISTWTPSWTTTSLSQVSQMNTNSNMLRETLQENAFAPTSPASVLNPDLTNDAALSEDSKYSTQLFATTEGEPSWSTGSSFNITERMTTLPVLSPTHPSVSQKKQQKESACINITNSQCQMLPYNYTTLTSVLSIVKSTEMEKFLKFFSYLSRLSCYQHIMLFGCSLALPECISDGDDSRVLLPCRTFCEAAKEGCEPVLGMVNASWPEFLKCSQFHNQTENDTTARVCFSPHQEKGKQTLCGGEESFLCASGICIPGKLQCNGYNDCDDWSDEVHCNCSDDLFHCNTGKCLNYTFVCDGYDDCGDLSDEENCDCNPMTDHQCGDGRCITADWVCDGDHDCIDKSDEINCSCHSQGLVECKNGQCIPSAFKCDGDKDCKDGSDEENCSEKCSPSHFKCRSGRCVLASRRCDGQADCEDDSDEDSCGCKERGLWECPLKKLCIKHTMICDGFPDCPDMMDEKNCSFCEKDELECANHECVPRELWCDGQADCSDTSDEWDCVTLSKNMNSLMFLTVHRSAADNHVCADEWQENLSQLACNQMGLGGPSKTVIVLEDGEMQHQKWLHLHSDWKSKNASTLHALLVNGQMCQSRSKVALLCTKEDCGHRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKRWVLTVAHCFEGRENAAVWKVVFGISNLDHPSSFMQTRLVKSIILHPRYNRAVVDYDISIVQLDEEINETSYVRPVCLPSKEQLVQPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEQCQSYFDMKTITSRMLCAGYESGTVDSCMGDSGGPLVCEQPAGRWTLFGLTSWGSVCFSKVLGPGVYSNVSHFIDWIEKQIYIHTFLLN", "length": 971, "header": "tr|A0A8V0YSI2-1|A0A8V0YE77_CHICK Computationally mapped isoform of Corin, serine peptidase OS=Gallus gallus OX=9031 GN=CORIN PE=3 SV=1 CANONICAL=A0A8V0YE77-1" }, "locus": { "chromosome": "4", "start_pos": 66275513, "end_pos": 66155307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032380.1", "url": "https://www.ensembl.org/id/ENSGALT00010032380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019149.1", "url": "https://www.ensembl.org/id/ENSGALP00010019149.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q80YN4-1", "protein_name": "Atrial natriuretic peptide-converting enzyme", "gene_name": "Corin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVSFNVRVSSVRRARCSCPGRCYLSCRVPPTTALHALNGFGRAGVLGETAGGTVGLGPSGTRGFLSGSKFQASGSLKDCFGAPPAPDVLRADSSVGEGCPQKLVTANLLRFLLLVLIPCICALIVLLAILLSFVGTLKKVYFKSNDSEPLVTDGEVRVPGVIHVNRYENTGAPSMPPSQSIPAWTPRAPSLEDQSHGNTSTCVNITHRQCQILPYHSTLAPLLPIVKNMDTEKFLKFFTYLHRLGCYQHILLFGCSLAFPKCIVDGDDRHGLLPCRSFCEAAKEGCESVLGMVNSSWPDSLRCSQFRYHTENNSDASRICFSLQQEHGKQSLCGGGESFLCTSGLCISKKLQCNGYNDCDDWSDEAHCNCSEDLFHCGTGKCLHHSLVCDGYDDCGDLSDEQNCDCNLTKEHRCGDGRCIAAEWVCDGDHDCVDKSDEVNCSCPSQGLVECRSGQCIPSTFQCDGDEDCKDGSDEENCSDRPTPCPGGDRGCLDSSCVESCAGSSLCDSDSSLSNCSHCEPITLELCMNLPYNLTHYPNYLGHRTQKEASISWESALFPALVQTNCYKYLMFFACTILVPKCDVNTGQRVPPCRLLCEHSKERCESVLGIVGLQWPEDTDCSQFPEQSSDNQTCLLPNEDVEECSPSHFKCRSGRCVLGSRRCDGQADCDDDSDEENCGCKERDLWECPLNKQCLKHTLICDGFPDCSDSMDEKNCSFCQDDELECANHECVPRDLWCDGWTDCSDSSDEWGCVTLSKNGNSSSFLTVHRSARDHHVCADGWQETLSQLACRQMGLGEPSVTELVQGQEGQQWLRLHSSWENLNGSTLQELLVHRRSCPSGSEISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGREDADVWKVVFGINNLDHPSGFMQTRFVKTILLHPRYSRAVVDYDISVVELSDDINETSYVRPVCLPSPREFLEPDTYCYITGWGHMGNKMPFKLQEGEVRIIPLEQCQSYFDMKTITNRMICAGYESGTVDSCMIDSGGPLVCERPGGQWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVDWIERQIYIQTFLQKKSQG", "length": 1111 }, "evidence": [ { "id": "A0A8V0YE77", "url": "https://omabrowser.org/oma/group/A0A8V0YE77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y5Q5-1", "protein_name": "Atrial natriuretic peptide-converting enzyme", "gene_name": "CORIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKQSPALAPEERCRRAGSPKPVLRADDNNMGNGCSQKLATANLLRFLLLVLIPCICALVLLLVILLSYVGTLQKVYFKSNGSEPLVTDGEIQGSDVILTNTIYNQSTVVSTAHPDQHVPAWTTDASLPGDQSHRNTSACMNITHSQCQMLPYHATLTPLLSVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGCTLAFPECIIDGDDSHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRICFSPQQENGKQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSLNNCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQMGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN", "length": 1042 }, "evidence": [ { "id": "A0A8V0YE77", "url": "https://omabrowser.org/oma/group/A0A8V0YE77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z319-1", "protein_name": "Atrial natriuretic peptide-converting enzyme", "gene_name": "Corin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRVSFSVRVSSVRRARCSCPGRCYLSCRVPPTTALRALNGLGCAGVPGETAGGAVGPGPLGTRGFLSGSKFQAPGSWKDCFGAPPAPDVLRADRSVGEGCPQKLVTANLLRFLLLVLIPCICALIVLLAILLSFVGTLKRVYFKSNDSEPLVTDGEARVPGVIPVNTVYYENTGAPSLPPSQSTPAWTPRAPSPEDQSHRNTSTCMNITHSQCQILPYHSTLAPLLPIVKNMDMEKFLKFFTYLHRLSCYQHILLFGCSLAFPECVVDGDDRHGLLPCRSFCEAAKEGCESVLGMVNSSWPDSLRCSQFRDHTETNSSVRKSCFSLQQEHGKQSLCGGGESFLCTSGLCVPKKLQCNGYNDCDDWSDEAHCNCSKDLFHCGTGKCLHYSLLCDGYDDCGDLSDEQNCDCNLTKEHRCGDGRCIAAEWVCDGDHDCVDKSDEVNCSCHSQGLVECRSGQCIPSTFQCDGDEDCKDGSDEENCSDSQTPCPEGEQGCLGSSCVESCAGSSLCDSDSSLSNCSQCEPITLELCMNLPYNHTHYPNYLGHRTQKEASISWESSLFPALVQTNCYKYLMFFACTILVPKCDVNTGQRIPPCRLLCEHSKERCESVLGIVGLQWPEDTDCNQFPEESSDNQTCLLPNEDVEECSPSHFKCRSGRCVLGSRRCDGQADCDDDSDEENCGCKERALWECPFNKQCLKHTLICDGFPDCPDSMDEKNCSFCQDNELECANHECVPRDLWCDGWVDCSDSSDEWGCVTLSKNGNSSSLLTVHKSAKEHHVCADGWRETLSQLACKQMGLGEPSVTKLIPGQEGQQWLRLYPNWENLNGSTLQELLVYRHSCPSRSEISLLCSKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGREDADVWKVVFGINNLDHPSGFMQTRFVKTILLHPRYSRAVVDYDISVVELSDDINETSYVRPVCLPSPEEYLEPDTYCYITGWGHMGNKMPFKLQEGEVRIIPLEQCQSYFDMKTITNRMICAGYESGTVDSCMGDSGGPLVCERPGGQWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVGWIERQIYIQTFLQKKSQG", "length": 1113 }, "evidence": [ { "id": "A0A8V0YE77", "url": "https://omabrowser.org/oma/group/A0A8V0YE77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "id": "GO:0003050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" }, { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" }, { "name": "regulation of renal sodium excretion", "id": "GO:0035813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1110, "end_pos": 1112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" }, { "id": "PS50038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FZ", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 348, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE77" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 890, "end_pos": 1123, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 1110, "end_pos": 1112 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 653, "end_pos": 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"glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE89" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE89" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YEA2-1", "uniprot_ac": "A0A8V0YEA2", "uniprot_id": "A0A8V0YEA2_CHICK", "mass": { "chemical_mass": 74829.0, "monoisotopic_mass": 74829.0 }, "refseq": { "ac": "XP_416731", "name": "lebercilin-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416731" }, "gene_names": [ { "name": "LCA5L", "type": "recommended", "evidence": [ { "id": "A0A8V0YEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2" } ] }, { "name": "LCA5L", "type": "synonym", "evidence": [ { "id": "XP_416731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416731" } ] } ], "protein_names": [ { "name": "Lebercilin-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2/entry#names_and_taxonomy" } ] }, { "name": "Leber congenital amaurosis 5-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2/entry#names_and_taxonomy" } ] }, { "name": "lebercilin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416731.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416731" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LCA5L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2", "locus": { "chromosome": "1", "start_pos": 108092001, "end_pos": 108107160, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013449", "url": "https://www.ensembl.org/id/ENSGALG00010013449" } ] } } ], "crossref": [ { "id": "A0A8V0YEA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "418522", "url": "https://www.ncbi.nlm.nih.gov/gene/418522", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MKHQETQ", "url": "https://omabrowser.org/oma/group/MKHQETQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEA2", "url": "https://www.orthodb.org/?gene=A0A8V0YEA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK10", "url": "https://www.orthodb.org/?gene=A0A8V0YK10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK15", "url": "https://www.orthodb.org/?gene=A0A8V0YK15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLRLRLPGCSAAAVRPRGNGGAQRLCRKIGSPSKYVTQTIPQSTEELEAAAEAEVMTEGNAVENAEVKIIKLTILRALSVTCSETARSSRCLELSGTEEKKMQKNERKRKKKKEQQIFSQNNKGGKKLPAKKIPHEKSSFLSLQNNTISQKKNKVAQRILSARLHKIKELKNEISDLQHKLEASNLENQVLKRLLYRHSKAIGGYESSESVLPDLLTRHYSEVSALRKHLRISQEEERRASRKLRKVEAELLKAKDDLQALYKLSEDKTLAERDELYHRLSVLTEKMEVNNKRIQSLEKQLKLNNSTFSRQLANENKKAVEAGIITKNLQMEINSLHQKIKEKDRQLYIKNIYTNRLLKIPKDKGDAVSHKKSLSINTSLQADKQHFRSLQLPQYQPQETEESLVLLHEEKKASEGKNQKAKASEAYTDAQCETEKQSSKKIPKPETFSRTHKEYLKENKPLTVHTCLEFISQEERKRDLLKQKPEKAEETLLNDSVKENNQEEDAVEEKEKKSEEQLSKSGKAGSDFLTPRNRTLSKLKKQYVFSETTENLHQGLPTSGAKSTKGNLCNQRHASQDQCKEAESKVKKLFGLYEQPFSKVTKTRQKDSSTEAEGCAHTIFSERKKSLMKELFGEGGVCKDNHSCSNRRGMERKL", "length": 656, "header": "tr|A0A8V0YEA2-1|A0A8V0YEA2_CHICK Isoform 1 of Lebercilin-like protein OS=Gallus gallus OX=9031 GN=LCA5L PE=3 SV=1 CANONICAL=A0A8V0YEA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2/entry", "sequence": { "sequence": "MAGLRLRLPGCSAAAVRPRGNGGAQRLCRKIGSPSKYVTQTIPQSTEELEAAAEAEVMTEGNAVENAEVKIIKLTILRALSVTCSETARSSRCLELSGTEEKKMQKNERKRKKKKEQQIFSQNNKGGKKLPAKKIPHEKSSFLSLQNNTISQKKNKVAQRILSARLHKIKELKNEISDLQHKLEASNLENQVLKRLLYRHSKAIGGYESSESVLPDLLTRHYSEVSALRKHLRISQEEERRASRKLRKVEAELLKAKDDLQALYKLSEDKTLAERDELYHRLSVLTEKMEVNNKRIQSLEKQLKLNNSTFSRQLANENKKAVEAGIITKNLQMEINSLHQKIKEKDRQLYIKNIYTNRLLKIPKDKGDAVSHKKSLSINTSLQADKQHFRSLQLPQYQPQETEESLVLLHEEKKASEGKNQKAKASEAYTDAQCETEKQSSKKIPKPETFSRTHKEYLKENKPLTVHTCLEFISQEERKRDLLKQKPEKAEETLLNDSVKENNQEEDAVEEKEKKSEEQLSKSGKAGSDFLTPRNRTLSKLKKQYVFSETTENLHQGLPTSGAKSTKGNLCNQRHASQDQCKEAESKVKKLFGLYEQPFSKVTKTRQKDSSTEAEGCAHTIFSERKKSLMKELFGEGGVCKDNHSCSNRRGMERKL", "length": 656, "header": "tr|A0A8V0YEA2-1|A0A8V0YEA2_CHICK Isoform 1 of Lebercilin-like protein OS=Gallus gallus OX=9031 GN=LCA5L PE=3 SV=1 CANONICAL=A0A8V0YEA2-1" }, "locus": { "chromosome": "1", "start_pos": 108107048, "end_pos": 108093528, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032379.1", "url": "https://www.ensembl.org/id/ENSGALT00010032379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019148.1", "url": "https://www.ensembl.org/id/ENSGALP00010019148.1" } ] } }, { "isoform_ac": "A0A8V0YK10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK10/entry", "sequence": { "sequence": "MRFVSSSSSFFFLPVCRKIGSPSKYVTQTIPQSTEELEAAAEAEVMTEGNAVENAEVKIIKLTILRALSVTCSETARSSRCLELSGTEEKKMQKNERKRKKKKEQQIFSQNNKGGKKLPAKKIPHEKSSFLSLQNNTISQKKNKVAQRILSARLHKIKELKNEISDLQHKLEASNLENQVLKRLLYRHSKAIGGYESSESVLPDLLTRHYSEVSALRKHLRISQEEERRASRKLRKVEAELLKAKDDLQALYKLSEDKTLAERDELYHRLSVLTEKMEVNNKRIQEKDRQLYIKNIYTNRLLKIPKDKGDAVSHKKSLSINTSLQADKQHFRSLQLPQYQPQETEESLVLLHEEKKASEGKNQKAKASEAYTDAQCETEKQSSKKIPKPETFSRTHKEYLKENKPLTVHTCLEFISQEERKRDLLKQKPEKAEETLLNDSVKENNQEEDAVEEKEKKSEEQLSKSGKAGSDFLTPRNRTLSKLKKQYVFSETTENLHQGLPTSGAKSTKGNLCNQRHASQDQCKEAESKVKKLFGLYEQPFSKVTKTRQKDSSTEAEGCAHTIFSERKKSLMKELFGEGGVCKDNHSCSNRRGMERKL", "length": 598, "header": "tr|A0A8V0YK10-1|A0A8V0YK10_CHICK Computationally mapped isoform of Lebercilin-like protein OS=Gallus gallus OX=9031 GN=LCA5L PE=3 SV=1 CANONICAL=A0A8V0YEA2-1" }, "locus": { "chromosome": "1", "start_pos": 108106749, "end_pos": 108093528, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032378.1", "url": "https://www.ensembl.org/id/ENSGALT00010032378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019147.1", "url": "https://www.ensembl.org/id/ENSGALP00010019147.1" } ] } }, { "isoform_ac": "A0A8V0YK15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK15/entry", "sequence": { "sequence": "MAGLRLRLPGCSAAAVRPRGNGGAQRLCRKIGSPSKYVTQTIPQSTEELEAAAEAEVMTEGNAVENAEVKIIKLTILRALSVTCSETARSSRCLELSGTEEKKMQKNERKRKKKKEQQIFSQNNKGGKKLPAKKIPHEKSSFLSLQNNTISQKKNKVAQRILSARLHKIKELKNEISDLQHKLEASNLENQVLKRLLYRHSKAIGGYESSESVLPDLLTRHYSEVSALRKHLRISQEEERRASRKLRKVEAELLKAKDDLQALYKLSEDKTLAERDELYHRLSVLTEKMEVNNKRIQEKDRQLYIKNIYTNRLLKIPKDKGDAVSHKKSLSINTSLQADKQHFRSLQLPQYQPQETEESLVLLHEEKKASEGKNQKAKASEAYTDAQCETEKQSSKKIPKPETFSRTHKEYLKENKPLTVHTCLEFISQEERKRDLLKQKPEKAEETLLNDSVKENNQEEDAVEEKEKKSEEQLSKSGKAGSDFLTPRNRTLSKLKKQYVFSETTENLHQGLPTSGAKSTKGNLCNQRHASQDQCKEAESKVKKLFGLYEQPFSKVTKTRQKDSSTEAEGCAHTIFSERKKSLMKELFGEGGVCKDNHSCSNRRGMERKL", "length": 610, "header": "tr|A0A8V0YK15-1|A0A8V0YK15_CHICK Computationally mapped isoform of Lebercilin-like protein OS=Gallus gallus OX=9031 GN=LCA5L PE=3 SV=1 CANONICAL=A0A8V0YEA2-1" }, "locus": { "chromosome": "1", "start_pos": 108107048, "end_pos": 108093528, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032383.1", "url": "https://www.ensembl.org/id/ENSGALT00010032383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019152.1", "url": "https://www.ensembl.org/id/ENSGALP00010019152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AG60-1", "protein_name": "Lebercilin-like protein", "gene_name": "Lca5l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLWTMSLADTTEAHTNEHFPSLALGSNRKSAEGKHSPGAGGLSRNSRASSGSVDYSRSRCSCTSLTSRYDYSEDFLSECSETAVSRHQPEQLLGKEKEKRKYNTCKFPQPKGQKDIPAEKRHIWNASFFSSQIQTIAKRRDTMTHRILSARLHKIKELKNELADIHRKLEATILENQFLKQLQLRHLKAIGTYVNSQNNLPQITVKHQNEVKNLRQLLRKSQEKERAVSRKLRETDSELLRTKDALQALQRLSEDKNLAEREELTHRLTDLTAKMEANDKKIQNLEKQLRLNNRSFSRQLAKENRKTLAAQTATKALQAEVRQLQQKLKEKDRELEIKNIYTNRILKNLHDKEDYPKVSSTKSVQADRKSLPFVNVRHQETQKSDVPFWITKDKKAKGNIVHKEKSTEINHDISYHVRKLPRQEESKRKCEANLTVLKNMPSPRVSWEQVATEQICAFHLECHSCTQTDLSKEVEHPKPQTSLETPRRPKERKEDQEKRAIPEEAEPTAKGSEVPEDAEDKALARAACDVGDAGDAGDAGDADHASDAGDVRDVVEDSEVIGAHELPGANQAGEVHGASEAGDVEPGRGRRKTPRSRKHYSFTEATENLHHGLPTSCRQASGSPHCRCRHCTGKHRSEQELRLEPAGYEPSFGKAARTRARATAFRDRKSSLMEELFGSGFAGRAGPNDGEAPSKSPQPGPQASAGNAFGDSKATVARSIQASPPEANRKTAV", "length": 734 }, "evidence": [ { "id": "A0A8V0YEA2", "url": "https://omabrowser.org/oma/group/A0A8V0YEA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7E3D8-1", "protein_name": "Lebercilin-like protein", "gene_name": "LCA5L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLAGPTETNLGGHFPGTAVENGGSSSKRESSSPGFPRNSNASDKSVDYSRSRCSCRSPSSHYDYSEDFLSACSETTARNNYLEKPTVKEKKEKKKYNVSKISQLKGQKEISVRKKHSWNVPFLNSQISVAAQRRDAMIHRILSARLHKIKELKNELADLHHKAEATVIENQFLKQVQLKHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQGKERATSRKLREMDGELLRTKDALQALQKISEENNLPEREELTQRLSILTAKMEANDKKIQDLEKQLRLNNKAFTRQLTFENRKTLAAQAATKTLQMEIKHLQQKLKEKDRELEIRNIYSNRIVGNLHDKEDYPKVSSTKSVQADRRSFPFISMRHQETQKSEDVASWTTKSKKTTGNNGHKEKSIEIIHAMPPCITKLPNQEDSKRKYEDLSKEEQHLEAQPSLKNTGQQRYRTENQEKKITLVKEEQELPPKRIEVIHPEGEGGQEDDTEKYKFKRSPEISDMGDMPDKNAAPHIKIPFRQRKHYSFTEAIENLHHGLPASGGLANAGSTRYPHSTGKHHSHSEEMKLEHPAIAYEPSFAKSYRTKAKDTTFREKKSNLMEELFGSDYVLKNNQTSTTVMKEPEETLQSTKIHHLPPSQASASNAFGDSGVTVVNSIKSSSPTEGNRKIII", "length": 670 }, "evidence": [ { "id": "A0A8V0YEA2", "url": "https://omabrowser.org/oma/group/A0A8V0YEA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95447-1", "protein_name": "Lebercilin-like protein", "gene_name": "LCA5L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLADLTKTNIDEHFFGVALENNRRSAACKRSPGTGDFSRNSNASNKSVDYSRSQCSCGSLSSQYDYSEDFLCDCSEKAINRNYLKQPVVKEKEKKKYNVSKISQSKGQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII", "length": 670 }, "evidence": [ { "id": "A0A8V0YEA2", "url": "https://omabrowser.org/oma/group/A0A8V0YEA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C0X0-2", "protein_name": "Lebercilin-like protein", "gene_name": "Lca5l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLWTMSLADTTEAHTNEHFPSLALGSNKKSTEGKRSPGAGGQSQNSQASNGSVDYSRSQCSCTSLTSHYDYSEDFLSDCSETAVRRLQSEKPLAKAKEKRKYNAGKLPQPRGQKDIPAEKKQFWNASLISSQIQTIAKRRDTMTHRILSARLHKIKELKNELADVHRKLEASAIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERAVSRKLRETDGELLRTKDVLQALQRLSEDKNLAEREELTDRLTDLTAKMEANDKKIQNLEKQLRLNNRSYSRQLAKENRKTLAAQTATKTLQAEVRQLQQKLKEKDRELEIKNIYTNRILKNLNDKEDYPKVSSTKSVQADRKSLPSVNMRHQETQKSDVPFWITKGKRGKGNIAHKEKSTETNHDIPYYVCKLPKQEESKRKYEANLTVLKSMPSPPASWGLVATEQICAFHLECHSCTHTADLSKEVEHRKPQTSLETPRRPKENKEDQEKRAIPAEAEPTAKESEAHKDAEDKALTRAAGNAGDAGDAGDAGNDREVVGEHKVVGAQEVVGAQELPGADEADEVHGAGEAPRDVEPGRGRRKTPRKHYSFTEATENLHHGLPTSCRQVSGSPHCRCRHDMGKHRSEQELRLEPAGYEPSFGKGAGARARARARATAFRDRKSSLMEELFGAGFAGRAGSSDSEAVSKSPQTGPQASAGNAFGDSRATVAGSIQASPTEANRKTVV", "length": 735 }, "evidence": [ { "id": "A0A8V0YEA2", "url": "https://omabrowser.org/oma/group/A0A8V0YEA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA2" }, { "id": "PF15619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lebercilin", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 349, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 643, "end_pos": 645 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YEC4-1", "uniprot_ac": "A0A8V0YEC4", "uniprot_id": "A0A8V0YEC4_CHICK", "mass": { "chemical_mass": 92681.0, "monoisotopic_mass": 92681.0 }, "refseq": {}, "gene_names": [ { "name": "NPAS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ] } ], "protein_names": [ { "name": "Neuronal PAS domain protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPAS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4", "locus": { "chromosome": "1", "start_pos": 133473345, "end_pos": 133377318, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013436", "url": "https://www.ensembl.org/id/ENSGALG00010013436" } ] } } ], "crossref": [ { "id": "A0A8V0YEC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016774", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016774", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395433", "url": "https://www.ncbi.nlm.nih.gov/gene/395433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395433", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPCRMPL", "url": "https://omabrowser.org/oma/group/RPCRMPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEC4", "url": "https://www.orthodb.org/?gene=A0A8V0YEC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK25", "url": "https://www.orthodb.org/?gene=A0A8V0YK25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKS2", "url": "https://www.orthodb.org/?gene=A0A8V0YKS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YML8", "url": "https://www.orthodb.org/?gene=A0A8V0YML8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZV0", "url": "https://www.orthodb.org/?gene=E1BZV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46055:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46055:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZV0", "url": "https://www.uniprot.org/uniprotkb/E1BZV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BZV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLWKNCLDNLMDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKTDNELEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYSNVPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQASLPSQPSCELLPQQLLPQATLQSQPAPLAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 827, "header": "tr|A0A8V0YEC4-1|A0A8V0YEC4_CHICK Isoform 1 of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=1 CANONICAL=A0A8V0YEC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4/entry", "sequence": { "sequence": "MLLLWKNCLDNLMDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKTDNELEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYSNVPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQASLPSQPSCELLPQQLLPQATLQSQPAPLAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 827, "header": "tr|A0A8V0YEC4-1|A0A8V0YEC4_CHICK Isoform 1 of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=1 CANONICAL=A0A8V0YEC4-1" }, "locus": { "chromosome": "1", "start_pos": 133472287, "end_pos": 133377463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032402.1", "url": "https://www.ensembl.org/id/ENSGALT00010032402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019169.1", "url": "https://www.ensembl.org/id/ENSGALP00010019169.1" } ] } }, { "isoform_ac": "A0A8V0YK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK25/entry", "sequence": { "sequence": "MKLASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKTDNELEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYSNVPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQASLPSQPSCELLPQQLLPQATLQSQPAPLAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 807, "header": "tr|A0A8V0YK25-1|A0A8V0YK25_CHICK Computationally mapped isoform of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=1 CANONICAL=A0A8V0YEC4-1" }, "locus": { "chromosome": "1", "start_pos": 133472287, "end_pos": 133428103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032395.1", "url": "https://www.ensembl.org/id/ENSGALT00010032395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019162.1", "url": "https://www.ensembl.org/id/ENSGALP00010019162.1" } ] } }, { "isoform_ac": "A0A8V0YKS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS2/entry", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKMPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQASLPSQPSCELLPQQLLPQATLQSQPAPLAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 777, "header": "tr|A0A8V0YKS2-1|A0A8V0YKS2_CHICK Computationally mapped isoform of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=1 CANONICAL=A0A8V0YEC4-1" }, "locus": { "chromosome": "1", "start_pos": 133472287, "end_pos": 133424291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032416.1", "url": "https://www.ensembl.org/id/ENSGALT00010032416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019181.1", "url": "https://www.ensembl.org/id/ENSGALP00010019181.1" } ] } }, { "isoform_ac": "A0A8V0YML8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML8/entry", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKTDNELEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYSNVPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 784, "header": "tr|A0A8V0YML8-1|A0A8V0YML8_CHICK Computationally mapped isoform of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=1 CANONICAL=A0A8V0YEC4-1" }, "locus": { "chromosome": "1", "start_pos": 133472287, "end_pos": 133424291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032412.1", "url": "https://www.ensembl.org/id/ENSGALT00010032412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019177.1", "url": "https://www.ensembl.org/id/ENSGALP00010019177.1" } ] } }, { "isoform_ac": "E1BZV0-1", "url": "https://www.uniprot.org/uniprotkb/E1BZV0/entry", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEISEIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTGGSIIYVSDSITPLLGHLPCDVLDQNLLNFLPEQEHSEIYKMLSSCMLMTDSASSDYLKTDNELEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYSNVPNSTCNGFDEAVPRAYRASPGKQICFVATVRLATPQFLKEMCIVEEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHEHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHMVVSYADVRVERRQEMGLEEVSSEVVSSALKDSGSSLDPDQHFNALDIGASILSASRTPSVSSRSSPKSSHTPKSDPASTPTKLTAEASTPLQRTSSTQQDLSAHRLSQPTALQASLPSQPSCELLPQQLLPQATLQSQPAPLAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELQKIQEQLCLVQDSSVQMFLQQPAVSLSFSNIQQPEPQPLQQRPGVISQQQLVLSPQLPGQIASPQTPSQQVLREASVISSQGPKAERSTELTTGSSRPTRSTATLFGPSTSLSRRGPGPSSGPGASAAGCSHDQQLRLLLSQPIQPMMPTSCNARHPSDLSMAGSQAKYSQNQQMFQSLEVQTSSSGSPIVLMGQAVLNQGFATTPPSQSSSLPPMQLQHQQHQQQRYLQVQTPSSLHNEQTDSLLLSSYSPQQGNMGYHQTQQQQQQQQLPRRSNSLSESSNLPQPLR", "length": 815, "header": "tr|E1BZV0-1|A0A8V0YEC4_CHICK Computationally mapped isoform of Neuronal PAS domain protein 2 OS=Gallus gallus OX=9031 GN=NPAS2 PE=4 SV=2 CANONICAL=A0A8V0YEC4-1" }, "locus": { "chromosome": "1", "start_pos": 133472287, "end_pos": 133424291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032407.1", "url": "https://www.ensembl.org/id/ENSGALT00010032407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019173.1", "url": "https://www.ensembl.org/id/ENSGALP00010019173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395433", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7ETJ2-1", "protein_name": "Neuronal PAS domain-containing protein 2 isoform X1", "gene_name": "Npas2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEICDVQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKMLSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDASLEPPQHFNALDMGASGLTTSPSPSVSSRSSHKSSHTAMSEPTSTPTKLMAENSNAALPRSATLPQELPVPGLSQAATMPAPLPSPSSCDLAKQLLPQTILQSPPAPMTQFSAQFSMFQSIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFGGAQRPASQQQLQQRPSAAQSQLVVDTALPGQITSTQVTNQHLLRDSNVIATQGPKPMRSSQLLPASGRSVSSLPSQFSSAAAVLPPGLSLTTAAPTSQDASQCQPSPDFSHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQAMFPSPDSHPASSSASTPVLLMGQAVLHPSFPTSQPSPLQPAQAQQQTPHYLQAPTSLHSEQPDSLLLSTFSQQPGTLGYATTQPTQPQPQRPSRRVSRLSESSGLQQPPR", "length": 819 }, "evidence": [ { "id": "A0A8V0YEC4", "url": "https://omabrowser.org/oma/group/A0A8V0YEC4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LTY6-1", "protein_name": "Neuronal PAS domain protein 2", "gene_name": "Npas2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKLDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPGTEEESMKGLHRSRTLRLCLRSEVHPVERASFSLYFLLQSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDLAKQLLPQSLPQTVLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSGAQRPAAQQPLQQRPSAPSQPPLVVNTPLPGQITSTQVTNQHLLRESNVMSAQGPKPIRSSQLLPASSRSLSSLPSQFSSTASVLPPGLSLTTVAPTPQDTSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVTFPSPDSHPTSSSAPTPVLLMGQAVLHPGFPASQPSPLQPTQVQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPAPLGYAATQPTQPQPPRPSRRVSRLSES", "length": 855 }, "evidence": [ { "id": "A0A8V0YEC4", "url": "https://omabrowser.org/oma/group/A0A8V0YEC4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97460-1", "protein_name": "Neuronal PAS domain-containing protein 2", "gene_name": "Npas2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHLPADVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCHVPLGKDVCFIATVRLATPQFLKEMCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYNYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPTEAMHPSAVKEKDSSLEPPQPFNALDMGASGLPSSPSPSASSRSSHKSSHTAMSEPTSTPTKLMAENSTTALPRPATLPQELPVQGLSQAATMPTALHSSASCDLTKQLLLQSLPQTGLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSSTQRPAAQQQLQQRPAAPSQPQLVVNTPLQGQITSTQVTNQHLLRESNVISAQGPKPMRSSQLLPASGRSLSSLPSQFSSTASVLPPGLSLTTIAPTPQDDSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVMFPSPDSHPTNSSASTPVLLMGQAVLHPSFPASRPSPLQPAQAQQQPPPYLQAPTSLHSEQPDSLLLSTFSQQPGTLGYAATQSTPPQPPRPSRRVSRLSES", "length": 816 }, "evidence": [ { "id": "A0A8V0YEC4", "url": "https://omabrowser.org/oma/group/A0A8V0YEC4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99743-1", "protein_name": "Neuronal PAS domain-containing protein 2", "gene_name": "NPAS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEYLKSDSDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRVPLGKEVCFIATVRLATPQFLKEMCIVDEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARCHQHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPSEALHSSALKDKGSSLEPRQHFNTLDVGASGLNTSHSPSASSRSSHKSSHTAMSEPTSTPTKLMAEASTPALPRSATLPQELPVPGLSQAATMPAPLPSPSSCDLTQQLLPQTVLQSTPAPMAQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSSTQRPEAQQQLQQRSAAVTQPQLGAGPQLPGQISSAQVTSQHLLRESSVISTQGPKPMRSSQLMQSSGRSGSSLVSPFSSATAALPPSLNLTTPASTSQDASQCQPSPDFSHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQTVFQNPDAHPANSSSAPMPVLLMGQAVLHPSFPASQPSPLQPAQARQQPPQHYLQVQAPTSLHSEQQDSLLLSTYSQQPGTLGYPQPPPAQPQPLRPPRRVSSLSESSGLQQPPR", "length": 824 }, "evidence": [ { "id": "A0A8V0YEC4", "url": "https://omabrowser.org/oma/group/A0A8V0YEC4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "CLOCK-BMAL transcription complex", "id": "GO:1990513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "response to redox state", "id": "GO:0051775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC4" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": 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"start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YEJ3-1", "uniprot_ac": "A0A8V0YEJ3", "uniprot_id": "A0A8V0YEJ3_CHICK", "mass": { "chemical_mass": 93177.0, "monoisotopic_mass": 93177.0 }, "refseq": { "ac": "NP_001186424", "name": "cadherin-17 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" }, "gene_names": [ { "name": "CDH17", "type": "recommended", "evidence": [ { "id": "A0A8V0YEJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3" } ] }, { "name": "CDH17", "type": "synonym", "evidence": [ { "id": "NP_001186424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" } ] }, { "name": "cadherin-17", "type": "synonym", "evidence": [ { "id": "NP_001186424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" } ] } ], "protein_names": [ { "name": "Cadherin-17", "type": "recommended", "evidence": [ { "id": "A0A8V0YEJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3/entry#names_and_taxonomy" } ] }, { "name": "Liver-intestine cadherin", "type": "synonym", "evidence": [ { "id": "A0A8V0YEJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3/entry#names_and_taxonomy" } ] }, { "name": "cadherin 17, LI cadherin (liver-intestine)", "type": "synonym", "evidence": [ { "id": "NP_001186424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" } ] }, { "name": "cadherin-17 precursor", "type": "synonym", "evidence": [ { "id": "NP_001186424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.18609.1, SRR13267654.130969.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_001186424.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDH17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3", "locus": { "chromosome": "2", "start_pos": 125569600, "end_pos": 125595457, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012171", "url": "https://www.ensembl.org/id/ENSGALG00010012171" } ] } } ], "crossref": [ { "id": "A0A8V0YEJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420225", "url": "https://www.ncbi.nlm.nih.gov/gene/420225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420225", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420225", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVNNEMP", "url": "https://omabrowser.org/oma/group/DVNNEMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186424", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKLCGLQFLLAVQWAACQNLGDLHLTGPLKDMNFSIPEGTGVRAIYQFTSESPDVIFRATGEKDGLIDIVPDTGILYLNGSLDWETKAVHKLQVEILNKNGDVVKGPCAVTIYVEDINDNPPKFDQAQYTGVVRQNSRAGKPFMRVHATDLDDPTTPHAQLNYSIPHHFPNPYSEMLFQINSLTGEISPSRTGSFYLDPQKQDTFTLVVSVKDMAGLTENAFKNSVDVKITVKESLWKAPPTITIKENSTQPHPVNISQVHSNEADVIYEVFEKETLAKLPFSIDQNGSIYVTEPLDREEKDAYSFFVITKDKGGELVDKPLKINIIVEDINDNPPVCQNAVTTLEVQENESGGSSIGTLSATDMDQKDTLNSRLKFKILSQDPAVPTSNLFFIQQDTGVLQLHGHSLNKRIASNYSLKVQVTDEVFQTICDVQIHVIDINDQIPIFEKSDYYSVTVAESLPVGTVLLEIQATDGDEPATGSSYIIYQVKEGDPDNTFIIETDPETNRGFLKINKALDFETAEVHNLVINATNPEPLVSGVQYNSSSLTLFKVFVTNVDEPPAFHKEVYTTELSEDVPVNTLVVTVEAHDPEGDAVRYSLEGDWRKWLRIDSTTGQIYTASALDREQEQVYRVDVVASEISNAAQKFKTPLVLNLKDVNDNAPRLNMDYPLFFCYPLRGGDRTLIRATDDDEQKFYSTITFSLKDDVATRNNWEILKVNATHAYLSPRHTNFEEKVYTVPMIISDNGVPPLEREVILEVNICTCSSENSCFIPVEREHSKPSTGQAIGILLGVLIVIGVIVGGAFFHMRYKEKNKKKSQQKDAKDQTECDKLNA", "length": 835, "header": "tr|A0A8V0YEJ3-1|A0A8V0YEJ3_CHICK Isoform 1 of Cadherin-17 OS=Gallus gallus OX=9031 GN=CDH17 PE=4 SV=1 CANONICAL=A0A8V0YEJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ3/entry", "sequence": { "sequence": "MLKLCGLQFLLAVQWAACQNLGDLHLTGPLKDMNFSIPEGTGVRAIYQFTSESPDVIFRATGEKDGLIDIVPDTGILYLNGSLDWETKAVHKLQVEILNKNGDVVKGPCAVTIYVEDINDNPPKFDQAQYTGVVRQNSRAGKPFMRVHATDLDDPTTPHAQLNYSIPHHFPNPYSEMLFQINSLTGEISPSRTGSFYLDPQKQDTFTLVVSVKDMAGLTENAFKNSVDVKITVKESLWKAPPTITIKENSTQPHPVNISQVHSNEADVIYEVFEKETLAKLPFSIDQNGSIYVTEPLDREEKDAYSFFVITKDKGGELVDKPLKINIIVEDINDNPPVCQNAVTTLEVQENESGGSSIGTLSATDMDQKDTLNSRLKFKILSQDPAVPTSNLFFIQQDTGVLQLHGHSLNKRIASNYSLKVQVTDEVFQTICDVQIHVIDINDQIPIFEKSDYYSVTVAESLPVGTVLLEIQATDGDEPATGSSYIIYQVKEGDPDNTFIIETDPETNRGFLKINKALDFETAEVHNLVINATNPEPLVSGVQYNSSSLTLFKVFVTNVDEPPAFHKEVYTTELSEDVPVNTLVVTVEAHDPEGDAVRYSLEGDWRKWLRIDSTTGQIYTASALDREQEQVYRVDVVASEISNAAQKFKTPLVLNLKDVNDNAPRLNMDYPLFFCYPLRGGDRTLIRATDDDEQKFYSTITFSLKDDVATRNNWEILKVNATHAYLSPRHTNFEEKVYTVPMIISDNGVPPLEREVILEVNICTCSSENSCFIPVEREHSKPSTGQAIGILLGVLIVIGVIVGGAFFHMRYKEKNKKKSQQKDAKDQTECDKLNA", "length": 835, "header": "tr|A0A8V0YEJ3-1|A0A8V0YEJ3_CHICK Isoform 1 of Cadherin-17 OS=Gallus gallus OX=9031 GN=CDH17 PE=4 SV=1 CANONICAL=A0A8V0YEJ3-1" }, "locus": { "chromosome": "2", "start_pos": 125593011, "end_pos": 125571070, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029199.1", "url": "https://www.ensembl.org/id/ENSGALT00010029199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016934.1", "url": "https://www.ensembl.org/id/ENSGALP00010016934.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGVGAARRSWAAAVVVLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPAAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVQRGDENLESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGNLVARVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDYEVVRLCELQIEARDNGFPPLSGHCKVVVQVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAALAAVGAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPAPKETPQEPPSLLDT", "length": 850, "header": "tr|A0A8V0YEJ4-1|A0A8V0YEJ4_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4/entry", "sequence": { "sequence": "MVGVGAARRSWAAAVVVLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPAAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVQRGDENLESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGNLVARVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDYEVVRLCELQIEARDNGFPPLSGHCKVVVQVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAALAAVGAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPAPKETPQEPPSLLDT", "length": 850, "header": "tr|A0A8V0YEJ4-1|A0A8V0YEJ4_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEJ4-1" }, "locus": { "chromosome": "13", "start_pos": 952028, "end_pos": 949479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029789.1", "url": "https://www.ensembl.org/id/ENSGALT00010029789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017343.1", "url": "https://www.ensembl.org/id/ENSGALP00010017343.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ4" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 131, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 556, "end_pos": 558 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YER6-1", "uniprot_ac": "A0A8V0YER6", "uniprot_id": "A0A8V0YER6_CHICK", "mass": { "chemical_mass": 37430.0, "monoisotopic_mass": 37430.0 }, "refseq": { "ac": "NP_001183965", "name": "transcriptional adapter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" }, "gene_names": [ { "name": "TADA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ] }, { "name": "TADA1L", "type": "synonym", "evidence": [ { "id": "NP_001183965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" } ] }, { "name": "TADA1", "type": "synonym", "evidence": [ { "id": "NP_001183965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" } ] } ], "protein_names": [ { "name": "Transcriptional adapter 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6/entry#names_and_taxonomy" } ] }, { "name": "Transcriptional adapter 1-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6/entry#names_and_taxonomy" } ] }, { "name": "transcriptional adapter 1", "type": "synonym", "evidence": [ { "id": "NP_001183965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" } ] }, { "name": "transcriptional adaptor 1 (HFI1 homolog, yeast)-like", "type": "synonym", "evidence": [ { "id": "NP_001183965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000148.1, HAEL01000762.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Jun 2, 2011 this sequence version replaced XP_426619.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001183965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965" } ] }, { "annotation": "Probably involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6#function" }, { "database": "UniProtKB", "id": "ARBA00003228", "url": "https://www.uniprot.org/uniprotkb/ARBA00003228#function" }, { "database": "UniProtKB", "id": "A0A8V0YES1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TADA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6", "locus": { "chromosome": "8", "start_pos": 4339066, "end_pos": 4321824, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013553", "url": "https://www.ensembl.org/id/ENSGALG00010013553" } ] } } ], "crossref": [ { "id": "A0A8V0YER6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YER6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22934", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22934", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769871", "url": "https://www.ncbi.nlm.nih.gov/gene/769871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769871", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIMTEDQ", "url": "https://omabrowser.org/oma/group/NIMTEDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YER6", "url": "https://www.orthodb.org/?gene=A0A8V0YER6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YES1", "url": "https://www.orthodb.org/?gene=A0A8V0YES1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21277:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21277:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12767", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12767", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001183965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YER6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YES1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YES1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATYVSELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDLEARRLLTQDNVHSHNDFLLAILTRCQILVSAPEGAGSLPWPGGSATKPGKPKGKKKISSVRQKFDHRFQPQNPLSGAQQFVAKDPQEEDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEDAVTAVVYAVENHLKDILTSVISRRKAYRLRDGHFKYAFGSNVNPQPYLKNSVVAYNNLIECPPTCVTPSAGQTVAPQPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHKEVIPAHTVYALNIERIVMKLWHPNHEELQQDKIHRQHLAAKEGLLLC", "length": 335, "header": "tr|A0A8V0YER6-1|A0A8V0YER6_CHICK Isoform 1 of Transcriptional adapter 1 OS=Gallus gallus OX=9031 GN=TADA1 PE=3 SV=1 CANONICAL=A0A8V0YER6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YER6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6/entry", "sequence": { "sequence": "MATYVSELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDLEARRLLTQDNVHSHNDFLLAILTRCQILVSAPEGAGSLPWPGGSATKPGKPKGKKKISSVRQKFDHRFQPQNPLSGAQQFVAKDPQEEDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEDAVTAVVYAVENHLKDILTSVISRRKAYRLRDGHFKYAFGSNVNPQPYLKNSVVAYNNLIECPPTCVTPSAGQTVAPQPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHKEVIPAHTVYALNIERIVMKLWHPNHEELQQDKIHRQHLAAKEGLLLC", "length": 335, "header": "tr|A0A8V0YER6-1|A0A8V0YER6_CHICK Isoform 1 of Transcriptional adapter 1 OS=Gallus gallus OX=9031 GN=TADA1 PE=3 SV=1 CANONICAL=A0A8V0YER6-1" }, "locus": { "chromosome": "8", "start_pos": 4335284, "end_pos": 4321864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032600.1", "url": "https://www.ensembl.org/id/ENSGALT00010032600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019319.1", "url": "https://www.ensembl.org/id/ENSGALP00010019319.1" } ] } }, { "isoform_ac": "A0A8V0YES1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES1/entry", "sequence": { "sequence": "MATYVSELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDLEARRLLTQDNEGAGSLPWPGGSATKPGKPKGKKKISSVRQKFDHRFQPQNPLSGAQQFVAKDPQEEDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEDAVTAVVYAVENHLKDILTSVISRRKAYRLRDGHFKYAFGSNVNPQPYLKNSVVAYNNLIECPPTCVTPSAGQTVAPQPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHKEVIPAHTVYALNIERIVMKLWHPNHEELQQDKIHRQHLAAKEGLLLC", "length": 313, "header": "tr|A0A8V0YES1-1|A0A8V0YES1_CHICK Computationally mapped isoform of Transcriptional adapter 1 OS=Gallus gallus OX=9031 GN=TADA1 PE=3 SV=1 CANONICAL=A0A8V0YER6-1" }, "locus": { "chromosome": "8", "start_pos": 4335284, "end_pos": 4321864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032610.1", "url": "https://www.ensembl.org/id/ENSGALT00010032610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019324.1", "url": "https://www.ensembl.org/id/ENSGALP00010019324.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 237, "start_aa": "Thr", "end_pos": 237, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:769871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769871", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QR06-1", "protein_name": "Transcriptional adapter 1", "gene_name": "TADA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILSSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNSLIESPPALSAPFAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLFC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S248-1", "protein_name": "Transcriptional adapter 1", "gene_name": "TADA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFSAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HE77-1", "protein_name": "Transcriptional adapter 1", "gene_name": "Tada1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFSAPCASQNSASQPHPDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BJQ7-1", "protein_name": "Transcriptional adapter 1", "gene_name": "Tada1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IPA1-1", "protein_name": "Transcriptional adapter 1-2", "gene_name": "Ada1-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTDRVLATKEALVVALGDNWERYRANMKNWFRSRWTKEEFDAESRKILTPDKLHLHNQFLLALLNKIDAFAPLENPPAVQTSSSSGNRSKRRKRSSRTFAERLNFELSDVLDFVAEDNMQIIRPPTTIGIPSDQQQQQLQSQRYCAQELFLPDAGFIMGRFLIGAWEIGLVSVDDNVAEYVAMAVQVLLKDLLSAIIKKRKHYKTSGEGNFYYDVGAPLRDPSLRNTVTRQKVDDTPLELDKELNTANFMRRQNDDVTFLSACEEVQPTERTVITLKDCQLALRDRNLIGSHAVYSINMERLNMMMH", "length": 308 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96BN2-1", "protein_name": "Transcriptional adapter 1", "gene_name": "TADA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LM9-1", "protein_name": "Transcriptional adapter 1", "gene_name": "Tada1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKEPQGDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFSAPCANQSPASQPHPDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "A0A8V0YER6", "url": "https://omabrowser.org/oma/group/A0A8V0YER6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YER6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 237 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YES7-1", "uniprot_ac": "A0A8V0YES7", "uniprot_id": "A0A8V0YES7_CHICK", "mass": { "chemical_mass": 104746.0, "monoisotopic_mass": 104746.0 }, "refseq": { "ac": "XP_040511563", "name": "complement component C6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511563" }, "gene_names": [ { "name": "C6", "type": "recommended", "evidence": [ { "id": "A0A8V0YES7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ] }, { "name": "C6", "type": "synonym", "evidence": [ { "id": "XP_040511563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511563" } ] } ], "protein_names": [ { "name": "Complement C6", "type": "synonym", "evidence": [ { "id": "A0A8V0YES7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7/entry#names_and_taxonomy" } ] }, { "name": "complement component C6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040511563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7", "locus": { "chromosome": "Z", "start_pos": 13496589, "end_pos": 13523114, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012485", "url": "https://www.ensembl.org/id/ENSGALG00010012485" } ] } } ], "crossref": [ { "id": "A0A8V0YES7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YES7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431585", "url": "https://www.ncbi.nlm.nih.gov/gene/431585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YYRKNFC", "url": "https://omabrowser.org/oma/group/YYRKNFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YES7", "url": "https://www.orthodb.org/?gene=A0A8V0YES7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS4", "url": "https://www.orthodb.org/?gene=A0A8V0YMS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45742:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45742:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21288", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21288", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-166665", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166665", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YES7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKTVLIQLILLSLVVGSCQGCYCEHYPWGSWSSCSKTCNYGTQTRHRQIKMDEYYNQNFCDRLCTKQESRACNQQTCPINCQLGDFGPWSECDPCIEKQFRVRKLLRPSQFGGQACTEPLVQSRPCFPAKLCNIVDVDCKNKFQCENGRCIAKKLECNGDNDCGDNSDERYCGRKKVVCSRKFESIPGVHLIGSGFHILSGESRGEVLGNSFNGGECRTVRRNETRKSYRVPANLEAVSFQVIDEEDDVKSDFYRDLTPLSDGDVGSSTSSHSSQRRSGIPGLFSKKRKVQITSSSSFKKAIEASHEKNSNFIRIHKVISVANFTMKESNLQLSDVFLKALNQLPLEYNYALYSRIFDDFGTHYYTSGKMGGSYDILYQYSSEELKNSGLSVDESMECIRTETTRRVFFRKKKKVSTECITNKMTVKHDGSILESAERSVSLVKGGRSEYAAALAWEKKGAFPGNTIFTNWLESTKDNPVVIDFEVSSIVDLVKNMPCAVTRRRNLRRALREYAGRFDPCQCAPCPNNGRPVLSGTECLCLCQAGTYGTNCEIRAPGYESVAVDGRWSCWSEWSSCDASFKRRRTRECNNPSPINGGKPCKGEREEEEDCYVSVFMDNGAPCINDDEAKSELDIVVGVLETGCSRPDPPENGFIRNEKNQYAVGEEAEIACVSGHVLIGYQFLRCLPDQTWTQQPVECQPSLCLRPPTSDSVEISPFKLHYNIGETVKLSCRAGFVVTGQTQYTCGKDLSWFPSILRSITCEKDEQTKIRGVCNPGQKQVGSECVCMNPEEDCGHYSEDICVLHALSEQHVTKPSCQFSAEKCLGEQSFHFLHAGPCHSTSSVHWAIERAKLSANSLKKVPCGYDTCYDWEECPESQMQCSCLMPYQCPREESQLHCIRMESTGRRKRVSHCVLAAMKCAGIGLEVLEEGSCLG", "length": 935, "header": "tr|A0A8V0YES7-1|A0A8V0YES7_CHICK Isoform 1 of Complement C6 OS=Gallus gallus OX=9031 GN=C6 PE=1 SV=1 CANONICAL=A0A8V0YES7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YES7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7/entry", "sequence": { "sequence": "MEKTVLIQLILLSLVVGSCQGCYCEHYPWGSWSSCSKTCNYGTQTRHRQIKMDEYYNQNFCDRLCTKQESRACNQQTCPINCQLGDFGPWSECDPCIEKQFRVRKLLRPSQFGGQACTEPLVQSRPCFPAKLCNIVDVDCKNKFQCENGRCIAKKLECNGDNDCGDNSDERYCGRKKVVCSRKFESIPGVHLIGSGFHILSGESRGEVLGNSFNGGECRTVRRNETRKSYRVPANLEAVSFQVIDEEDDVKSDFYRDLTPLSDGDVGSSTSSHSSQRRSGIPGLFSKKRKVQITSSSSFKKAIEASHEKNSNFIRIHKVISVANFTMKESNLQLSDVFLKALNQLPLEYNYALYSRIFDDFGTHYYTSGKMGGSYDILYQYSSEELKNSGLSVDESMECIRTETTRRVFFRKKKKVSTECITNKMTVKHDGSILESAERSVSLVKGGRSEYAAALAWEKKGAFPGNTIFTNWLESTKDNPVVIDFEVSSIVDLVKNMPCAVTRRRNLRRALREYAGRFDPCQCAPCPNNGRPVLSGTECLCLCQAGTYGTNCEIRAPGYESVAVDGRWSCWSEWSSCDASFKRRRTRECNNPSPINGGKPCKGEREEEEDCYVSVFMDNGAPCINDDEAKSELDIVVGVLETGCSRPDPPENGFIRNEKNQYAVGEEAEIACVSGHVLIGYQFLRCLPDQTWTQQPVECQPSLCLRPPTSDSVEISPFKLHYNIGETVKLSCRAGFVVTGQTQYTCGKDLSWFPSILRSITCEKDEQTKIRGVCNPGQKQVGSECVCMNPEEDCGHYSEDICVLHALSEQHVTKPSCQFSAEKCLGEQSFHFLHAGPCHSTSSVHWAIERAKLSANSLKKVPCGYDTCYDWEECPESQMQCSCLMPYQCPREESQLHCIRMESTGRRKRVSHCVLAAMKCAGIGLEVLEEGSCLG", "length": 935, "header": "tr|A0A8V0YES7-1|A0A8V0YES7_CHICK Isoform 1 of Complement C6 OS=Gallus gallus OX=9031 GN=C6 PE=1 SV=1 CANONICAL=A0A8V0YES7-1" }, "locus": { "chromosome": "Z", "start_pos": 13522017, "end_pos": 13498126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029936.1", "url": "https://www.ensembl.org/id/ENSGALT00010029936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017420.1", "url": "https://www.ensembl.org/id/ENSGALP00010017420.1" } ] } }, { "isoform_ac": "A0A8V0YMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS4/entry", "sequence": { "sequence": "MEKTVLIQLILLSLVVGSCQGCYCEHYPWGSWSSCSKTCNYGTQTRHRQIKMDEYYNQNFCDRLCTKQESRACNQQTCPINCQLGDFGPWSECDPCIEKQFRVRKLLRPSQFGGQACTEPLVQSRPCFPAKLCNIVDVDCKNKFQCENGRCIAKKLECNGDNDCGDNSDERYCGRKKVVCSRKFETSFAFFTESRGEVLGNSFNGGECRTVRRNETRKSYRVPANLEAVSFQVIDEEDDVKSDFYRDLTPLSDGDVGSSTSSHSSQRRSGIPGLFSKKRKVQITSSSSFKKAIEASHEKNSNFIRIHKVISVANFTMKESNLQLSDVFLKALNQLPLEYNYALYSRIFDDFGTHYYTSGKMGGSYDILYQYSSEELKNSGLSVDESMECIRTETTRRVFFRKKKKVSTECITNKMTVKHDGSILESAERSVSLVKGGRSEYAAALAWEKKGAFPGNTIFTNWLESTKDNPVVIDFEVSSIVDLVKNMPCAVTRRRNLRRALREYAGRFDPCQCAPCPNNGRPVLSGTECLCLCQAGTYGTNCEIRAPGYESVAVDGRWSCWSEWSSCDASFKRRRTRECNNPSPINGGKPCKGEREEEEDCYVSVFMDNGAPCINDDEAKSELDIVVGVLETGCSRPDPPENGFIRNEKNQYAVGEEAEIACVSGHVLIGYQFLRCLPDQTWTQQPVECQPSLCLRPPTSDSVEISPFKLHYNIGETVKLSCRAGFVVTGQTQYTCGKDLSWFPSILRSITCEKDEQTKIRGVCNPGQKQVGSECVCMNPEEDCGHYSEDICVLHALSEQHVTKPSCQFSAEKCLGEQSFHFLHAGPCHSTSSVHWAIERAKLSANSLKKVPCGYDTCYDWEECPESQMQCSCLMPYQCPREESQLHCIRMESTGRRKRVSHCVLAAMKCAGIGLEVLEEGSCLG", "length": 925, "header": "tr|A0A8V0YMS4-1|A0A8V0YMS4_CHICK Computationally mapped isoform of Complement C6 OS=Gallus gallus OX=9031 GN=C6 PE=1 SV=1 CANONICAL=A0A8V0YES7-1" }, "locus": { "chromosome": "Z", "start_pos": 13522017, "end_pos": 13498126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029946.1", "url": "https://www.ensembl.org/id/ENSGALT00010029946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017423.1", "url": "https://www.ensembl.org/id/ENSGALP00010017423.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-166665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166665", "resource": "Reactome", "description": "Terminal pathway of complement" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q6D8-1", "protein_name": "Complement component C6", "gene_name": "C6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRHLTLCFILLVMLIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQVVVNDYYWKNLCDKLCIKQETRECNLQTCPINCVLGDYGTWSDCDPCTEKQVKVKSVLRPSQFGGQPCTEPLVTFQPCVPSKLCKIEETNCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCTRIYTPIPSVQLMGTGFHFLAGEPRGEVLDNSFTGGICKLVKTSRASNPYRVSANLENVNFEVQTIEDDLKTEFYKNLISFEKNKNEDSLSVDERTKFFPIPIFHFSEKNEHSHYSSAFNKVIKASHKKDSSFIRIHKLIKVLNFTMKATDLQLSDVFLKALVHLPLEYNSAVYSRIFDDFGTHYFTSGSLGGKYDLIYQFSRQELQNSGLTEEEAQNCVQYETKKLKFLYMEIHKEDTCTKNKLSEKYGGSFLQGSEKSISLVQGGRSQQAAALAWEKGTSGPEENVYSEWLESVKENPAVVDYKLAPITDLVRNIPCAVTKRNNLRRALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCERRSPGYKSDAVDGNWGCWSSWSACNAAYRRSRTRECNNPAPQRGGQSCGGKDQQEEDCTVSIMENVGQPCINDDEEMKEVDLAEPEAESGCSQPPLPENAFTWNEKKLYSVGEEVEISCLTGFTAVGFQYLRCLPDRTWSQGDVECQRTSCLKPVVQDVLTISPFQRVYQIGESIELTCPRGFVVAGPSRYTCKEDSWTPPISNSLTCEQAILTKSKDLCPPGQKQSGSKCICMSPEEDCSAYSEDLCIFDGGSSQYFTSSACKFLAGKCLNNTQSHFVHSGSCQEGLQLEWGLERLKLAVNSTKRVSCGYNTCYDWENCSAHTSNCVCLLPPQCSKDENQLYCVKIGSSMREKTVNICTLGAVRCANIKVEILNPGRCPD", "length": 934 }, "evidence": [ { "id": "A0A8V0YES7", "url": "https://omabrowser.org/oma/group/A0A8V0YES7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MM86-1", "protein_name": "Complement component C6", "gene_name": "C6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARHSVLYFILLSALIDKSQACFCDHYPWSQWSSCSKTCNSGTQTRQRRIVTDKYYFENFCGQLCTKQESRECNWQTCPINCRLGDYGPWSDCDPCVQKRFKVRSILRPSQFGGQPCTEPLMTFQPCIPSKLCKIEEIDCKNKFRCDSGRCIASKLECNGENDCGDNSDERNCGRKKTVCSRSHNPIPGVQLMGMGFHFLAGEPRGEVLDNSFTGGVCRTVKSSRASNPYRVPANLENVNFEVQTKEDDLEADFYDDLIPLEDNKDQEALGSGLATSSFRVPIFYSSKRSQSSSHSSAFKQAIQASQKKASSFIRIHKVIKVLNFTMKTKDLQLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSKEELKNSGLTKEEAKNCIRIETKKRFLFVKKTKVEHRCTTNKLSEKYEGSFMQGSEKSISLVQGGRSAYAAALAWEKGSPVPEERVFSDWLESVKENPSVIDFALAPITDLVRNIPCAVTRRNNLRRAFREYAAKFDPCQCARCPNSGRPVLSGTECLCVCQSGTYGENCERRSPDYKSNAVDGNWGCWSSWSSCDATYRRSRTRECNNPAPQQGGKRCEGERRQEEHCTFSIMQNDGQPCISDDEDMKETDLPELESDSGCPQPVPPENGFIRNEKKQYSVGEEVEILCFTGFKAVGYQYFRCLPDRSWRQGDVECQRTECLKPIVPEGLTLSPFQTLYKIGDSIELTCPRGLVVNGPSRYTCSGDSWTPPISDSLSCEKDVLTGLRGHCQPGQKQLGSECVCMSPEEDCGHYSEEICVLDTTSSDYFTSSACKLLAEKCLNNQQLHFLHIGSCEEGPQLKWGLERIKLSSSSTKNESCGYDTCYNWEKCSATTSKCVCLLPSQCTKGGDQLFCVQIGSSANGKTMNICEVGAVKCAKREMEILHSGRC", "length": 932 }, "evidence": [ { "id": "A0A8V0YES7", "url": "https://omabrowser.org/oma/group/A0A8V0YES7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P13671-1", "protein_name": "Complement component C6", "gene_name": "C6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRSVLYFILLNALINKGQACFCDHYAWTQWTSCSKTCNSGTQSRHRQIVVDKYYQENFCEQICSKQETRECNWQRCPINCLLGDFGPWSDCDPCIEKQSKVRSVLRPSQFGGQPCTAPLVAFQPCIPSKLCKIEEADCKNKFRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAVCTRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGGICKTVKSSRTSNPYRVPANLENVGFEVQTAEDDLKTDFYKDLTSLGHNENQQGSFSSQGGSSFSVPIFYSSKRSENINHNSAFKQAIQASHKKDSSFIRIHKVMKVLNFTTKAKDLHLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVLFAKKTKVEHRCTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEVDLPEIEADSGCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGNSWTPPISNSLTCEKDTLTKLKGHCQLGQKQSGSECICMSPEEDCSHHSEDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLHFLHIGSCQDGRQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA", "length": 934 }, "evidence": [ { "id": "A0A8V0YES7", "url": "https://omabrowser.org/oma/group/A0A8V0YES7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q811M5-1", "protein_name": "Complement component C6", "gene_name": "C6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRHLTLCFILLIILIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQIVVNDYYRDNSCDQLCTKQETRQCNVETCPINCVLGDYGTWSDCDPCIRKQVKVRSVLRPSQFGGQPCTEPLVTFQPCVPSELCKIEETDCKNKFLCDSGRCIPSKLKCNGENDCGDNSDERNCGRTKPVCSRTYTPIPSVQLMGAGFHFLAGEPRGDVPDNSFTGGICKSVRSSRTSNPHRVPANLENVNFEVQTIEDDLKTDFYKDLATIGKNKNEDRSLSGEKKDSFYVPIFYSSKKSENFQRNSGFKNAIEASHKKDSSFVRIHKVIKVLNFTMKTTDLQLSDVFLKALIHLPLEYNFALYSRIFDDFGTHYFTSGSLGGKYDLLYQFSRQELQNSGLTEEETRNCVRYETKKRFLFFTKTYKEDRCTTNRLSEKYKGSFLQGSEKSISLVQGGRSQQAAALAWEKGSSGPEANVFSEWLESVKENPAVVDYELAPIIDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCEKRSPDYKSNAVDGNWGCWSSWSACNAAYRRSRSRECNNPEPQRGGQRCEGKHWQEEDCTFSIMEKVGQPCISDDEEIKEVDLAEPEADSGCPQPPLPENAFVWNEKKLYSVGEEVEISCLTGFKAVGYQYFRCLPDRTWRQGDVECQRTECLKPVVQDVLTISPFQSVYKIGESIELTCPRGFVVAGPSRYTCKGDSWTPPIPNSLSCEKDILTKSKGLCQPGQKQSGSECVCMSPEEDCSSYSEDLCIFDEGSSQYFTSSACKFLAEKCLNSNQFHFVHAGSCQEGPQLEWGLERLKLAMKSTKRVPCGYDTCYDWEKCSAHTSNCVCLLPPQCPKDENQLHCVKMGSSMRGKTVNICTLGAVRCANRKVEILNPGRCLD", "length": 934 }, "evidence": [ { "id": "A0A8V0YES7", "url": "https://omabrowser.org/oma/group/A0A8V0YES7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" }, { "name": "membrane attack complex", "id": "GO:0005579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" }, { "name": "other organism cell membrane", "id": "GO:0044218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YES7" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YES7", "url": 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CANONICAL=A0A8V0YEW3-1" }, "locus": { "chromosome": "Z", "start_pos": 51492461, "end_pos": 51482019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030038.1", "url": "https://www.ensembl.org/id/ENSGALT00010030038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017456.1", "url": "https://www.ensembl.org/id/ENSGALP00010017456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YEW5-1", "uniprot_ac": "A0A8V0YEW5", "uniprot_id": "A0A8V0YEW5_CHICK", "mass": { "chemical_mass": 112015.0, "monoisotopic_mass": 112015.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112530482", "type": "recommended", "evidence": [ { "id": "A0A8V0YEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112530482", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YEW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEW5", "url": "https://www.orthodb.org/?gene=A0A8V0YEW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00692", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00692", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHMRRQCQATGSWCQTCRMDNYNTNACRCWSGNPQPSARKKRRLRADTSSRFQPAAALQPATPGSLSLDLAAAVTTTLMTTKPERVSTGIRGPVMINGTTVGALLLGRSSASMLGLFVLPGVIDADFQGEIQIMVYTPFPPIKIEKGQRIAQLVPLEQLTKALTPCQSSPRGEQGFGSSGGLALLSLNLRDRPKKTVTLKYREEEIKLQGLLDTGADSSIVSPEIWPPHWPLQAAIATVTGIGGLSLAKKSPPLQIHLDEQVVHTSVSVAPLPPTLQCLIGRNVLSQLGALQPGLPNPAMLPYNWPLLIIDLKDCFFTITLHPEDTKRFAFTLPALNREHPDQRFEWTVLPQGMKNSPTLCQLYVDHALQPLRREWKQMVIYHYMDDILFAQPEAFTQEQIWQIEKTLNREGLMIAPEKVQLSAPRKYLGWAMTNTIVTPQKLQLNTEIETLHDAQRLLGDLQWLRPVVGIPNELLESLRPFLQGTDPAQPVTVTTQHKRLLQQIIDCIIHGSVRRCDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQQSKTLLQKTELLAEVTKKGRERTLQITGMEPVCVQLSVQKDTLTWYVQHSPELQDALLRAGSMVSMEKIPNVSLHWIGQWSWLRIPKRPETPLQNAITAYTDAGRKSRTAAVTWQQGGSWRHHLIVADDKDSLQTLELVAVVWAMMNLIDPLFVVTDSLYVAGVCHRIEEAYIKKVQNLWLYELFVQLQRAIRIREHSYAVVLVRGHKWEIDLGEGNARADRLVSLAQRPLVSQHVLAREAHSMFHQNAKGLRREFQITYEDAKAIVRLCPVCSHHNGGMGLGLGVSPRGLKANENWQMDVTHVGEFGQLKYVHVSIDTYSHFMWATAQSGEKAMYVERHLSCCFAVMGISLQIKTDNGPAYTSRRLGEFLQTWGVKHSTGIPNSPTGQAIVERGNCGWTADPARSCFSPPGSVQVKQLLWITVSHRTMMGVGERNAELR", "length": 1000, "header": "tr|A0A8V0YEW5-1|A0A8V0YEW5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC112530482 PE=3 SV=1 CANONICAL=A0A8V0YEW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5/entry", "sequence": { "sequence": "MGHMRRQCQATGSWCQTCRMDNYNTNACRCWSGNPQPSARKKRRLRADTSSRFQPAAALQPATPGSLSLDLAAAVTTTLMTTKPERVSTGIRGPVMINGTTVGALLLGRSSASMLGLFVLPGVIDADFQGEIQIMVYTPFPPIKIEKGQRIAQLVPLEQLTKALTPCQSSPRGEQGFGSSGGLALLSLNLRDRPKKTVTLKYREEEIKLQGLLDTGADSSIVSPEIWPPHWPLQAAIATVTGIGGLSLAKKSPPLQIHLDEQVVHTSVSVAPLPPTLQCLIGRNVLSQLGALQPGLPNPAMLPYNWPLLIIDLKDCFFTITLHPEDTKRFAFTLPALNREHPDQRFEWTVLPQGMKNSPTLCQLYVDHALQPLRREWKQMVIYHYMDDILFAQPEAFTQEQIWQIEKTLNREGLMIAPEKVQLSAPRKYLGWAMTNTIVTPQKLQLNTEIETLHDAQRLLGDLQWLRPVVGIPNELLESLRPFLQGTDPAQPVTVTTQHKRLLQQIIDCIIHGSVRRCDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQQSKTLLQKTELLAEVTKKGRERTLQITGMEPVCVQLSVQKDTLTWYVQHSPELQDALLRAGSMVSMEKIPNVSLHWIGQWSWLRIPKRPETPLQNAITAYTDAGRKSRTAAVTWQQGGSWRHHLIVADDKDSLQTLELVAVVWAMMNLIDPLFVVTDSLYVAGVCHRIEEAYIKKVQNLWLYELFVQLQRAIRIREHSYAVVLVRGHKWEIDLGEGNARADRLVSLAQRPLVSQHVLAREAHSMFHQNAKGLRREFQITYEDAKAIVRLCPVCSHHNGGMGLGLGVSPRGLKANENWQMDVTHVGEFGQLKYVHVSIDTYSHFMWATAQSGEKAMYVERHLSCCFAVMGISLQIKTDNGPAYTSRRLGEFLQTWGVKHSTGIPNSPTGQAIVERGNCGWTADPARSCFSPPGSVQVKQLLWITVSHRTMMGVGERNAELR", "length": 1000, "header": "tr|A0A8V0YEW5-1|A0A8V0YEW5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC112530482 PE=3 SV=1 CANONICAL=A0A8V0YEW5-1" }, "locus": { "chromosome": "W", "start_pos": 2197308, "end_pos": 2194309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028347.1", "url": "https://www.ensembl.org/id/ENSGALT00010028347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016243.1", "url": "https://www.ensembl.org/id/ENSGALP00010016243.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW5" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEW5", "url": 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"chromosome": "23", "start_pos": 491526, "end_pos": 520661, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014470", "url": "https://www.ensembl.org/id/ENSGALG00010014470" } ] } } ], "crossref": [ { "id": "A0A8V0YHN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037136", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037136", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "386579", "url": "https://www.ncbi.nlm.nih.gov/gene/386579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5L9", "url": "https://www.orthodb.org/?gene=A0A3Q2U5L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3ADZ8", "url": "https://www.orthodb.org/?gene=A0A3Q3ADZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AVG7", "url": "https://www.orthodb.org/?gene=A0A3Q3AVG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN2", "url": "https://www.orthodb.org/?gene=A0A8V0YHN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP02", "url": "https://www.orthodb.org/?gene=A0A8V0YP02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP12", "url": "https://www.orthodb.org/?gene=A0A8V0YP12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQT6", "url": "https://www.orthodb.org/?gene=A0A8V0YQT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVU9", "url": "https://www.orthodb.org/?gene=A0A8V0YVU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVW3", "url": "https://www.orthodb.org/?gene=A0A8V0YVW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-198753", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-199920", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-442742", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442742", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-444257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-444257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-881907", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-881907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U5L9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AVG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AVG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AVG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AVG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLCWDVHQQSSPAPTSATSCTQSCRARMAALFFSRSAEAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 756, "header": "tr|A0A8V0YHN2-1|A0A8V0YHN2_CHICK Isoform 1 of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U5L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L9/entry", "sequence": { "sequence": "MLRLLFRSKPRIQEAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 730, "header": "tr|A0A3Q2U5L9-1|A0A8V0YHN2_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 509408, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034790.1", "url": "https://www.ensembl.org/id/ENSGALT00010034790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020389.1", "url": "https://www.ensembl.org/id/ENSGALP00010020389.1" } ] } }, { "isoform_ac": "A0A3Q3ADZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADZ8/entry", "sequence": { "sequence": "MPLAQLAEPWPNMELVQLDTEAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 737, "header": "tr|A0A3Q3ADZ8-1|A0A8V0YHN2_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 520573, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034824.1", "url": "https://www.ensembl.org/id/ENSGALT00010034824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020404.1", "url": "https://www.ensembl.org/id/ENSGALP00010020404.1" } ] } }, { "isoform_ac": "A0A3Q3AVG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AVG7/entry", "sequence": { "sequence": "MERDPKLPRICTFLTLWLHRKHRAKPCSLQLPAPSPLPSPGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 738, "header": "tr|A0A3Q3AVG7-1|A0A8V0YHN2_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 505990, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034779.1", "url": "https://www.ensembl.org/id/ENSGALT00010034779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020383.1", "url": "https://www.ensembl.org/id/ENSGALP00010020383.1" } ] } }, { "isoform_ac": "A0A8V0YHN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2/entry", "sequence": { "sequence": "MSHLCWDVHQQSSPAPTSATSCTQSCRARMAALFFSRSAEAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 756, "header": "tr|A0A8V0YHN2-1|A0A8V0YHN2_CHICK Isoform 1 of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 508880, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034786.1", "url": "https://www.ensembl.org/id/ENSGALT00010034786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020386.1", "url": "https://www.ensembl.org/id/ENSGALP00010020386.1" } ] } }, { "isoform_ac": "A0A8V0YP02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP02/entry", "sequence": { "sequence": "MNGQAAPEEGGNPPCKAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 732, "header": "tr|A0A8V0YP02-1|A0A8V0YP02_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 517025, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034801.1", "url": "https://www.ensembl.org/id/ENSGALT00010034801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020395.1", "url": "https://www.ensembl.org/id/ENSGALP00010020395.1" } ] } }, { "isoform_ac": "A0A8V0YP12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP12/entry", "sequence": { "sequence": "MELVQLDTENGQAAPEEGGNPPCKAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 740, "header": "tr|A0A8V0YP12-1|A0A8V0YP12_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 520537, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034833.1", "url": "https://www.ensembl.org/id/ENSGALT00010034833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020406.1", "url": "https://www.ensembl.org/id/ENSGALP00010020406.1" } ] } }, { "isoform_ac": "A0A8V0YQT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT6/entry", "sequence": { "sequence": "MPLAQLAEPWPNMELVQLDTENGQAAPEEGGNPPCKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 734, "header": "tr|A0A8V0YQT6-1|A0A8V0YQT6_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 520573, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034813.1", "url": "https://www.ensembl.org/id/ENSGALT00010034813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020399.1", "url": "https://www.ensembl.org/id/ENSGALP00010020399.1" } ] } }, { "isoform_ac": "A0A8V0YVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVU9/entry", "sequence": { "sequence": "MLSICPPEFKGMNFQPCGKSPSRLQAKSDITWVEKDLVDSTDKGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 741, "header": "tr|A0A8V0YVU9-1|A0A8V0YHN2_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 512962, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034795.1", "url": "https://www.ensembl.org/id/ENSGALT00010034795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020392.1", "url": "https://www.ensembl.org/id/ENSGALP00010020392.1" } ] } }, { "isoform_ac": "A0A8V0YVW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVW3/entry", "sequence": { "sequence": "MPLAQLAEPWPNMELVQLDTEGEGVVKEINITHHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQDVQLVKGAMAATYSALNSSKPSPQLKPIESSILAQRRVKKLPSTTL", "length": 719, "header": "tr|A0A8V0YVW3-1|A0A8V0YHN2_CHICK Computationally mapped isoform of Ribosomal protein S6 kinase OS=Gallus gallus OX=9031 GN=RPS6KA1 PE=3 SV=1 CANONICAL=A0A8V0YHN2-1" }, "locus": { "chromosome": "23", "start_pos": 520573, "end_pos": 493655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034838.1", "url": "https://www.ensembl.org/id/ENSGALT00010034838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020408.1", "url": "https://www.ensembl.org/id/ENSGALP00010020408.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-198753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198753", "resource": "Reactome", "description": "ERK/MAPK targets" }, { "id": "R-GGA-199920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199920", "resource": "Reactome", "description": "CREB phosphorylation" }, { "id": "R-GGA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-GGA-442742", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442742", "resource": "Reactome", "description": "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" }, { "id": "R-GGA-444257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-444257", "resource": "Reactome", "description": "RSK activation" }, { "id": "R-GGA-881907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-881907", "resource": "Reactome", "description": "Gastrin-CREB signalling pathway via PKC and MAPK" }, { "id": "R-GGA-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "ribosomal protein S6 kinase activity", "id": "GO:0004711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "positive regulation of hepatic stellate cell activation", "id": "GO:2000491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X3D6-1", "A0A8V0XW11-1", "A0A1D5NWT4-1", "A0A8V1A4Q4-1", "A0A8V0YHN2-1" ], "evidence": [ { "id": "R-GGA-198746", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198746" } ] }, { "id": "R-GGA-199895", "name": "RSK1/2/3 phosphorylates CREB at Serine 119", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XW11-1", "A0A1D5NWT4-1", "A0A8V0YHN2-1" ], "evidence": [ { "id": "R-GGA-199895", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199895" } ] }, { "id": "R-GGA-442724", "name": "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XW11-1", "A0A1D5NWT4-1", "A0A8V0YSH3-1", "A0A8V0YHN2-1" ], "evidence": [ { "id": "R-GGA-442724", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442724" } ] }, { "id": "R-GGA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XW11-1", "A0A1D5NWT4-1", "A0A8V0YSH3-1", "A0A8V0YHN2-1" ], "evidence": [ { "id": "R-GGA-9029434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029434" } ] }, { "id": "R-GGA-9824994", "name": "RPS6KA1-dependent phosphorylation of MITF-M", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08156-1", "A0A8V0YHN2-1" ], "evidence": [ { "id": "R-GGA-9824994", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9824994" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": 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{ "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": 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"https://www.ensembl.org/id/ENSGALP00010020394.1" } ] } }, { "isoform_ac": "A0A3Q3AQ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQ02/entry", "sequence": { "sequence": "MHYQFEILRYIYESVELSGLEDIRHEASDFPCKVAKHPRNKNRNRYRDVSPFDHSRIKLNQGDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSIKCAQYWPRKEEKEMFFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPEYGPVVVHCSAGIGRSGTFCLVDTCLLLMDKRKDPSSVDVKQVLLEMRKYRMGLIQTADQLRFSYLAVIEGAKFIMGDASVQEQWKELSNEDLDPPPEHTPPPPRPPKRTSEMHNGRMHEHAEFFPKHQVVEEEIRCSVSTAEETVSDGRVFSSVPLITDSTSQDTEIRRRTVGENLHVTAHKEESKSESVEEDDENMMTTWKPFLVNICMFTFLTAGAYLCYRVCFH", "length": 434, "header": "tr|A0A3Q3AQ02-1|A0A8V0YHN7_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPN1 PE=3 SV=1 CANONICAL=A0A8V0YHN7-1" }, "locus": { "chromosome": "20", "start_pos": 13896251, "end_pos": 13881378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034783.1", "url": "https://www.ensembl.org/id/ENSGALT00010034783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020385.1", "url": "https://www.ensembl.org/id/ENSGALP00010020385.1" } ] } }, { "isoform_ac": "A0A3Q3AWY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AWY5/entry", "sequence": { "sequence": "MTRQPYSQDIRHEASDFPCKVAKHPRNKNRNRYRDVSPFDHSRIKLNQGDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSIKCAQYWPRKEEKEMFFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPEYGPVVVHCSAGIGRSGTFCLVDTCLLLMDKRKDPSSVDVKQVLLEMRKYRMGLIQTADQLRFSYLAVIEGAKFIMGDASVQEQWKELSNEDLDPPPEHTPPPPRPPKRTSEMHNGRMHEHAEFFPKHQVVEEEIRCSVSTAEETVSDGRVFSSVPLITDSTSQDTEIRRRTVGENLHVTAHKEESKSESVEEDDENMMTTWKPFLVNICMFTFLTAGAYLCYRVCFH", "length": 421, "header": "tr|A0A3Q3AWY5-1|A0A8V0YHN7_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPN1 PE=3 SV=1 CANONICAL=A0A8V0YHN7-1" }, "locus": { "chromosome": "20", "start_pos": 13907889, "end_pos": 13881378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034789.1", "url": "https://www.ensembl.org/id/ENSGALT00010034789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020388.1", "url": "https://www.ensembl.org/id/ENSGALP00010020388.1" } ] } }, { "isoform_ac": "A0A8V0YHN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7/entry", "sequence": { "sequence": "MQSRQPGPREQQQQQQLEPEPEPESPEQRVLGSQAGRGVPAMEIEKEFHRLDQAASWAAIYQDIRHEASDFPCKVAKHPRNKNRNRYRDVSPFDHSRIKLNQGDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSIKCAQYWPRKEEKEMFFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPEYGPVVVHCSAGIGRSGTFCLVDTCLLLYVSNFYLQMDKRKDPSSVDVKQVLLEMRKYRMGLIQTADQLRFSYLAVIEGAKFIMGDASVQEQWKELSNEDLDPPPEHTPPPPRPPKRTSEMHNGRMHEHAEFFPKHQVVEEEIRCSVSTAEETVSDGRVFSSVPLITDSTSQDTEIRRRTVGENLHVTAHKEESKSESVEEDDENMMTTWKPFLVNICMFTFLTAGAYLCYRVCFH", "length": 483, "header": "tr|A0A8V0YHN7-1|A0A8V0YHN7_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPN1 PE=3 SV=1 CANONICAL=A0A8V0YHN7-1" }, "locus": { "chromosome": "20", "start_pos": 13919746, "end_pos": 13881378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034794.1", "url": "https://www.ensembl.org/id/ENSGALT00010034794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020391.1", "url": "https://www.ensembl.org/id/ENSGALP00010020391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-354192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "resource": "Reactome", "description": "Integrin signaling" }, { "id": "R-GGA-6807004", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "resource": "Reactome", "description": "Negative regulation of MET activity" }, { "id": "R-GGA-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-GGA-912694", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "resource": "Reactome", "description": "Regulation of IFNA/IFNB signaling" }, { "id": "R-GGA-982772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-982772", "resource": "Reactome", "description": "Growth hormone receptor signaling" }, { "id": "R-GGA-9860927", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860927", "resource": "Reactome", "description": "Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells" } ], "orthologs": [ { "uniprot_canonical_ac": "P18031-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "PTPN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT", "length": 435 }, "evidence": [ { "id": "A0A8V0YHN7", "url": "https://omabrowser.org/oma/group/A0A8V0YHN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20417-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "Ptpn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMEKEFEQIDKAGNWAAIYQDIRHEASDFPCRIAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHVPPPPRPPKRTLEPHNGKCKELFSNHQWVSEESCEDEDILAREESRAPSIAVHSMSSMSQDTEVRKRMVGGGLQSAQASVPTEEELSPTEEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH", "length": 432 }, "evidence": [ { "id": "A0A8V0YHN7", "url": "https://omabrowser.org/oma/group/A0A8V0YHN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35821-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 1", "gene_name": "Ptpn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLDLPPEHVPPPPRPPKRTLEPHNGKCKELFSSHQWVSEETCGDEDSLAREEGRAQSSAMHSVSSMSPDTEVRRRMVGGGLQSAQASVPTEEELSSTEEEHKAHWPSHWKPFLVNVCMATLLATGAYLCYRVCFH", "length": 432 }, "evidence": [ { "id": "A0A8V0YHN7", "url": "https://omabrowser.org/oma/group/A0A8V0YHN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "endosome lumen", "id": "GO:0031904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "sorting endosome", "id": "GO:0097443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097443", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "positive regulation of receptor catabolic process", "id": "GO:2000646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "IRE1-mediated unfolded protein response", "id": "GO:0036498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor-beta signaling pathway", "id": "GO:0035791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "regulation of intracellular protein transport", "id": "GO:0033157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "negative regulation of vascular endothelial growth factor receptor signaling pathway", "id": "GO:0030948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030948", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "negative regulation of PERK-mediated unfolded protein response", "id": "GO:1903898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "regulation of hepatocyte growth factor receptor signaling pathway", "id": "GO:1902202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" }, { "name": "insulin receptor recycling", "id": "GO:0038020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-GGA-1168445", "name": "PTP1B binds the GH receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNY4-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-1168445", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1168445" } ] }, { "id": "R-GGA-1169192", "name": "PTP1B dephosphorylates GHR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNY4-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-1169192", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169192" } ] }, { "id": "R-GGA-377643", "name": "Dephosphorylation of inactive SRC by PTPB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX1-1", "F1NSA8-1", "A0A8V0ZDU6-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-377643", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-377643" } ] }, { "id": "R-GGA-6807027", "name": "PTPN1 and PTPN2 dephosphorylate MET", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X4H3-1", "A0M8T9-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-6807027", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807027" } ] }, { "id": "R-GGA-74733", "name": "Insulin receptor de-phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2TZZ7-1", "A0A8V1AFM7-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-74733", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74733" } ] }, { "id": "R-GGA-9865167", "name": "PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-9865224" ], "output_participant_list": [ "R-GGA-9865163" ], "enzyme_list": [ "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-9865167", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9865167" } ] }, { "id": "R-GGA-997311", "name": "Dephosphorylation of TYK2 by PTP1B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X5W9-1", "A0A8V0ZSN8-1", "A0A8V0YHN7-1" ], "evidence": [ { "id": "R-GGA-997311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-997311" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-9865163", "participant_name": "phospho-ANXA2 [cytosol]", "crossref": [ { "id": "XP_046780507.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010024693", "database": "ENSEMBL", "url": "" }, { "id": "NP_990682.1", "database": "RefSeq", "url": "" }, { "id": "P17785", "database": "PRO", "url": "" }, { "id": "XP_040562137.1", "database": "RefSeq", "url": "" }, { "id": "XP_015134249.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010060304", "database": "ENSEMBL", "url": "" }, { "id": "XP_025009571.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780509.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780508.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780504.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010037063", "database": "ENSEMBL", "url": "" }, { "id": "XP_046780506.1", "database": "RefSeq", "url": "" }, { "id": "P17785", "database": "UniProt", "url": "" }, { "id": "XP_046780505.1", "database": "RefSeq", "url": "" }, { "id": "XP_025009569.1", "database": "RefSeq", "url": "" }, { "id": "1BT6", "database": "PDB", "url": "" } ] }, { "participant_id": "R-GGA-9865224", "participant_name": "phospho-ANXA2 [cytosol]", "crossref": [ { "id": "P17785", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010024693", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010037063", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010060304", "database": "ENSEMBL", "url": "" }, { "id": "1BT6", "database": "PDB", "url": "" }, { "id": "P17785", "database": "PRO", "url": "" }, { "id": "XP_046780508.1", "database": "RefSeq", "url": "" }, { "id": "XP_015134249.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780505.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780507.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780506.1", "database": "RefSeq", "url": "" }, { "id": "XP_025009571.1", "database": "RefSeq", "url": "" }, { "id": "XP_025009569.1", "database": "RefSeq", "url": "" }, { "id": "NP_990682.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780504.1", "database": "RefSeq", "url": "" }, { "id": "XP_040562137.1", "database": "RefSeq", "url": "" }, { "id": "XP_046780509.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM182", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH46", "locus": { "chromosome": "1", "start_pos": 134184640, "end_pos": 134160420, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013012", "url": "https://www.ensembl.org/id/ENSGALG00010013012" } ] } } ], "crossref": [ { "id": "A0A8V0YH46", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH46", "database": 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"n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YL81-1", "uniprot_ac": "A0A8V0YL81", "uniprot_id": "A0A8V0YL81_CHICK", "mass": { "chemical_mass": 88067.0, "monoisotopic_mass": 88067.0 }, "refseq": { "ac": "XP_040516713", "name": "PR domain zinc finger protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516713" }, "gene_names": [ { "name": "PRDM4", "type": "recommended", "evidence": [ { "id": "A0A8V0YL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ] }, { "name": "PRDM4", "type": "synonym", "evidence": [ { "id": "XP_040516713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516713" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 4", "type": "recommended", "evidence": [ { "id": "A0A8V0YL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81/entry#names_and_taxonomy" } ] }, { "name": "PR domain zinc finger protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040516713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516713" } ] }, { "name": "PR domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040516713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516713" } ] }, { "annotation": "May function as a transcription factor involved in cell differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YZC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC0#function" }, { "database": "UniProtKB", "id": "ARBA00059546", "url": "https://www.uniprot.org/uniprotkb/ARBA00059546#function" }, { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81#function" }, { "database": "UniProtKB", "id": "PIRNR037161", "url": "https://www.uniprot.org/uniprotkb/PIRNR037161#function" }, { "database": "UniProtKB", "id": "A0A8V0YSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL1#function" }, { "database": "UniProtKB", "id": "A0A8V0YSV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRDM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81", "locus": { "chromosome": "1", "start_pos": 53389044, "end_pos": 53364540, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015583", "url": "https://www.ensembl.org/id/ENSGALG00010015583" } ] } } ], "crossref": [ { "id": "A0A8V0YL81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL81", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19189", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19189", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418065", "url": "https://www.ncbi.nlm.nih.gov/gene/418065", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041493", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041493", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418065", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418065", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTGPHEL", "url": "https://omabrowser.org/oma/group/QTGPHEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL81", "url": "https://www.orthodb.org/?gene=A0A8V0YL81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSL1", "url": "https://www.orthodb.org/?gene=A0A8V0YSL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSV6", "url": "https://www.orthodb.org/?gene=A0A8V0YSV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZC0", "url": "https://www.orthodb.org/?gene=A0A8V0YZC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040516713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYPRMNEMNLSPVGMDQLTSSSVSNALPVSGSHLGLAASPSHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGIPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPNTINVDSNPALSVPSNPSALDPYQPSGTVGLEPGIVPMDSRTVNAHGAQNMHPSDSHEVALDSTITMESVSRVTSPISTDGMTEELTMDDVAGDHSQIPNGSRSHEPLAVDTVGSNLTPDSVGHGGVIPIHSSTLELPVPVVMEPDHIAGRVAGMSASTLNDSIHTVAMSTNSVSVALSTSHNLASLDSVALHEVGLSLEPVAVSSINQEVAMGPGHVDVSADNLAFVPSSLQMEDSNSNKENMATLFTIWCTLCDKAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSLMGAEVGVWTRETIPVRTCFGPLIGQQSHSLEVADWTDKAASHIWKIYHSGVLEFCIITTDETECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSRDIPPEHELFFYYSRDYARQLGVPEHPDVHICHCGKECASYADFKAHLSSHIHSHLPSQGHSSSHGPGHGKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCEKLFMRRQDLKQHVLTHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKICKGPTSSLSAPEEEEEDSEEELIDSLRTEDCRINNGVYSTGDALTGHK", "length": 801, "header": "tr|A0A8V0YL81-1|A0A8V0YL81_CHICK Isoform 1 of PR domain zinc finger protein 4 OS=Gallus gallus OX=9031 GN=PRDM4 PE=4 SV=1 CANONICAL=A0A8V0YL81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81/entry", "sequence": { "sequence": "MYPRMNEMNLSPVGMDQLTSSSVSNALPVSGSHLGLAASPSHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGIPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPNTINVDSNPALSVPSNPSALDPYQPSGTVGLEPGIVPMDSRTVNAHGAQNMHPSDSHEVALDSTITMESVSRVTSPISTDGMTEELTMDDVAGDHSQIPNGSRSHEPLAVDTVGSNLTPDSVGHGGVIPIHSSTLELPVPVVMEPDHIAGRVAGMSASTLNDSIHTVAMSTNSVSVALSTSHNLASLDSVALHEVGLSLEPVAVSSINQEVAMGPGHVDVSADNLAFVPSSLQMEDSNSNKENMATLFTIWCTLCDKAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSLMGAEVGVWTRETIPVRTCFGPLIGQQSHSLEVADWTDKAASHIWKIYHSGVLEFCIITTDETECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSRDIPPEHELFFYYSRDYARQLGVPEHPDVHICHCGKECASYADFKAHLSSHIHSHLPSQGHSSSHGPGHGKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCEKLFMRRQDLKQHVLTHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKICKGPTSSLSAPEEEEEDSEEELIDSLRTEDCRINNGVYSTGDALTGHK", "length": 801, "header": "tr|A0A8V0YL81-1|A0A8V0YL81_CHICK Isoform 1 of PR domain zinc finger protein 4 OS=Gallus gallus OX=9031 GN=PRDM4 PE=4 SV=1 CANONICAL=A0A8V0YL81-1" }, "locus": { "chromosome": "1", "start_pos": 53388183, "end_pos": 53371533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037504.1", "url": "https://www.ensembl.org/id/ENSGALT00010037504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021707.1", "url": "https://www.ensembl.org/id/ENSGALP00010021707.1" } ] } }, { "isoform_ac": "A0A8V0YSL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL1/entry", "sequence": { "sequence": "MASSQCEWLMYFTLCFLRWTLIVSVPNFEFVFVPHDAFFHTMQSVLRNALVSVSLLLTSALCSLPSRMNEMNLSPVGMDQLTSSSVSNALPVSGSHLGLAASPSHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGIPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPNTINVDSNPALSVPSNPSALDPYQPSGTVGLEPGIVPMDSRTVNAHGAQNMHPSDSHEVALDSTITMESVSRVTSPISTDGMTEELTMDDVAGDHSQIPNGSRSHEPLAVDTVGSNLTPDSVGHGGVIPIHSSTLELPVPVVMEPDHIAGRVAGMSASTLNDSIHTVAMSTNSVSVALSTSHNLASLDSVALHEVGLSLEPVAVSSINQEVAMGPGHVDVSADNLAFVPSSLQMEDSNSNKENMATLFTIWCTLCDKAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSLMGAEVGVWTRETIPVRTCFGPLIGQQSHSLEVADWTDKAASHIWKIYHSGVLEFCIITTDETECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSRDIPPEHELFFYYSRDYARQLGVPEHPDVHICHCGKECASYADFKAHLSSHIHSHLPSQGHSSSHGPGHGKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCEKLFMRRQDLKQHVLTHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKICKGPTSSLSAPEEEEEDSEEELIDSLRTEDCRINNGVYSTGDALTGHK", "length": 864, "header": "tr|A0A8V0YSL1-1|A0A8V0YL81_CHICK Computationally mapped isoform of PR domain zinc finger protein 4 OS=Gallus gallus OX=9031 GN=PRDM4 PE=4 SV=1 CANONICAL=A0A8V0YL81-1" }, "locus": { "chromosome": "1", "start_pos": 53388183, "end_pos": 53372530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037499.1", "url": "https://www.ensembl.org/id/ENSGALT00010037499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021704.1", "url": "https://www.ensembl.org/id/ENSGALP00010021704.1" } ] } }, { "isoform_ac": "A0A8V0YSV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV6/entry", "sequence": { "sequence": "MKIEQKLNEKKNATIQRMNEMNLSPVGMDQLTSSSVSNALPVSGSHLGLAASPSHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGIPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPNTINVDSNPALSVPSNPSALDPYQPSGTVGLEPGIVPMDSRTVNAHGAQNMHPSDSHEVALDSTITMESVSRVTSPISTDGMTEELTMDDVAGDHSQIPNGSRSHEPLAVDTVGSNLTPDSVGHGGVIPIHSSTLELPVPVVMEPDHIAGRVAGMSASTLNDSIHTVAMSTNSVSVALSTSHNLASLDSVALHEVGLSLEPVAVSSINQEVAMGPGHVDVSADNLAFVPSSLQMEDSNSNKENMATLFTIWCTLCDKAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSLMGAEVGVWTRETIPVRTCFGPLIGQQSHSLEVADWTDKAASHIWKIYHSGVLEFCIITTDETECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSRDIPPEHELFFYYSRDYARQLGVPEHPDVHICHCGKECASYADFKAHLSSHIHSHLPSQGHSSSHGPGHGKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCEKLFMRRQDLKQHVLTHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKICKGPTSSLSAPEEEEEDSEEELIDSLRTEDCRINNGVYSTGDALTGHK", "length": 814, "header": "tr|A0A8V0YSV6-1|A0A8V0YL81_CHICK Computationally mapped isoform of PR domain zinc finger protein 4 OS=Gallus gallus OX=9031 GN=PRDM4 PE=4 SV=1 CANONICAL=A0A8V0YL81-1" }, "locus": { "chromosome": "1", "start_pos": 53388183, "end_pos": 53364556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037509.1", "url": "https://www.ensembl.org/id/ENSGALT00010037509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021711.1", "url": "https://www.ensembl.org/id/ENSGALP00010021711.1" } ] } }, { "isoform_ac": "A0A8V0YZC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC0/entry", "sequence": { "sequence": "MEEMRLCILDRKQSTVLRFVFLIWLSTVGHCCQVRLVYLGHGIITVMNEMNLSPVGMDQLTSSSVSNALPVSGSHLGLAASPSHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGIPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPNTINVDSNPALSVPSNPSALDPYQPSGTVGLEPGIVPMDSRTVNAHGAQNMHPSDSHEVALDSTITMESVSRVTSPISTDGMTEELTMDDVAGDHSQIPNGSRSHEPLAVDTVGSNLTPDSVGHGGVIPIHSSTLELPVPVVMEPDHIAGRVAGMSASTLNDSIHTVAMSTNSVSVALSTSHNLASLDSVALHEVGLSLEPVAVSSINQEVAMGPGHVDVSADNLAFVPSSLQMEDSNSNKENMATLFTIWCTLCDKAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSLMGAEVGVWTRETIPVRTCFGPLIGQQSHSLEVADWTDKAASHIWKIYHSGVLEFCIITTDETECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSRDIPPEHELFFYYSRDYARQLGVPEHPDVHICHCGKECASYADFKAHLSSHIHSHLPSQGHSSSHGPGHGKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCEKLFMRRQDLKQHVLTHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKICKGPTSSLSAPEEEEEDSEEELIDSLRTEDCRINNGVYSTGDALTGHK", "length": 843, "header": "tr|A0A8V0YZC0-1|A0A8V0YL81_CHICK Computationally mapped isoform of PR domain zinc finger protein 4 OS=Gallus gallus OX=9031 GN=PRDM4 PE=4 SV=1 CANONICAL=A0A8V0YL81-1" }, "locus": { "chromosome": "1", "start_pos": 53388183, "end_pos": 53372409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037493.1", "url": "https://www.ensembl.org/id/ENSGALT00010037493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021703.1", "url": "https://www.ensembl.org/id/ENSGALP00010021703.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 758, "start_aa": "Thr", "end_pos": 758, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr758", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418065", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418065", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZM81-1", "protein_name": "PR domain zinc finger protein 4", "gene_name": "PRDM4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNAALSIANNPSALDPYQSNGNVGLEPGIVSIDARSVNTHGAQSLHPTDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVAGEHTQIPNGSRSHEPLSVDSVSSNLAAETVGHGGVIPIHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPPSLQIEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYTEFKAHLTSHIHNHLPSQGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAQEEEEDDDSEEEELADSVGTEDCRINSAVYSAEESLSTHK", "length": 801 }, "evidence": [ { "id": "A0A8V0YL81", "url": "https://omabrowser.org/oma/group/A0A8V0YL81/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1R3R6-1", "protein_name": "PR domain zinc finger protein 4", "gene_name": "prdm4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDMNLSPVGMDQLSVPVSASHLGLPTSPTHNPITTPGMPVAIPSLGPSLGPLPSALSLMLPMGPLGDRGVMCGLPERNYTLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPSSLNMDGTLSVSNNNPSGLDPYSGPGGPLEQGLVTLDTRQVGGQADLHQGGSHEVQLGATGLTMESRVSSPMSPDGIEEDLATMEGVVVAESQQQLGSRSQTHEGLAGVDSSGGVMPLHGAGLELPVVMEQEHMGGRVGSGGTGAGGPGTLSEALHSAGELNSGVVSVVLTGAMLPQTQLERVSLHGPSGLGLEQVNVSAQVSLGPDNSLVLVNSTLQLEDSTSNKENMATAFNIWCTLCERSYPSDCPEHGPVTFIPDTPIQSRARLSLPRPLCLRISVTDEPIGVFSRESIPSRTCFGPMVGQHCSSVELTDWSDKDTPQIWKMFHNDIQEFCIVTTDEHECNWMMFVRKARTTGEQNLVAYIDNGKLYFCTTREILPDQELLFYFSRDYSRQLGVPRVPEGQICHCGKECASFTEFKSHLGSHAQSHSPTQDHPAHPGHSQSHSQDKVTNEPLRSTSSPQWQCHSDVNEHSSSSSGNGHGRERKFKCSMCTRAFTTSTKLNVHFMGHMGMRPHKCSYCSKAFSDPSNLRKHLRIHTGQKNFRCTVCGKSFTQKAHVESHMVIHIGAKNLKCDHCDKMFVRKQDLKQHMYSHSLDRQINCPKCDKQFLKPDHLKKHLNSHEGKRDFICEKCNKGFLTKYHLTRHLKICKGPKIGRGATQGEEEEEEDEEEEEEEDEEREAEIHPANQEECAIGMGGYASEKNM", "length": 822 }, "evidence": [ { "id": "A0A8V0YL81", "url": "https://omabrowser.org/oma/group/A0A8V0YL81/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80V63-1", "protein_name": "PR domain zinc finger protein 4", "gene_name": "Prdm4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNDMNLSPVGMEQLSSSSVSNALPVSGSHLGLAASPSHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPVGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQANGNVGLELGIVSIDSRSVNTHGAQSLHPNDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVTGEHPQIPNGSRSHEPLSVDSVSNSLTAEAVGHGGVIPIHGNGLELPVVMETDHIANRVNGMSDSTLSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPSSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGTDVVGVLPLIGVWTAETIPVRTCFGPLIGQQSHSLEVAEWTDKAVNHVWKIYHTGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPESELLFYYSRNYAQQIGVPEHPDVHLCNCGKECSSYSEFKAHLTSHIHNHLPSQGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKEPSSSSSAQEEEDDESEEEDLADSMRTEDCRMGSAVYSTDESLSAHK", "length": 803 }, "evidence": [ { "id": "A0A8V0YL81", "url": "https://omabrowser.org/oma/group/A0A8V0YL81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZP2-1", "protein_name": "PR domain zinc finger protein 4", "gene_name": "Prdm4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNDMNLSPVGMEQLSSSSVSNALPVSGSHLGLAASPSHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQANGNVGLELGIVSIDSRSVNTHGAQSLHPNDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVTGEHSQIPNGSRSHEPLSVDSVSNNLTADTVGHGGVIPIHGNGLELPVVMETDHIANRVNGISDSVLSDSIHTVAMSTNSVSVALSTSHNFASLESVSLQEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPSSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGTDVGVWTAETIPVRTCFGPLIGQQSHSMEVAEWTDKAVSHVWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYSEFKAHLTSHIHNHLPSQGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGRRDYVCEKCTKAYLTKYHLTRHLKACKEPASSSSAQDDEDEDGDSGEDGLPGSMTTEGCRMSSAVYSADESLSAHK", "length": 798 }, "evidence": [ { "id": "A0A8V0YL81", "url": "https://omabrowser.org/oma/group/A0A8V0YL81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKN5-1", "protein_name": "PR domain zinc finger protein 4", "gene_name": "PRDM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK", "length": 801 }, "evidence": [ { "id": "A0A8V0YL81", "url": "https://omabrowser.org/oma/group/A0A8V0YL81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 619, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL81" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 414, "end_pos": 531, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 758 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 89, "end_pos": 91 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YID9-1", "uniprot_ac": "A0A8V0YID9", "uniprot_id": "A0A8V0YID9_CHICK", "mass": { "chemical_mass": 94162.0, "monoisotopic_mass": 94162.0 }, "refseq": { "ac": "NP_001384495", "name": "prolactin receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" }, "gene_names": [ { "name": "PRLR", "type": "recommended", "evidence": [ { "id": "A0A8V0YID9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ] }, { "name": "PRL-R", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "PRLRb", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "PRLR", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] } ], "protein_names": [ { "name": "Prolactin receptor", "type": "recommended", "evidence": [ { "id": "A0A8V0YID9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9/entry#names_and_taxonomy" } ] }, { "name": "PRL-R", "type": "synonym", "evidence": [ { "id": "A0A8V0YID9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9/entry#names_and_taxonomy" } ] }, { "name": "cPRLR", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "dPRLR-dSPEF2 fusion", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "equates to base 1078-1204 of D13154", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "prolactin receptor b", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "name": "prolactin receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_001384495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000087.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ] }, { "annotation": "A comprehensive survey for the presence or absence of ev21 and incomplete duplication (ID) of prolactin receptor (PRLR) and sperm flagellar protein 2 (SPEF2) genes across 1,994 birds from 52 chicken breeds, three commercial hybrid groups, and the Red Jungle Fowl revealed that almost all LF breeds have both ev21 and ID.", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" }, { "database": "PubMed", "id": "29253229", "url": "https://glygen.org/publication/PubMed/29253229" } ] }, { "annotation": "DPRLR causes differences in immune responses between early and late feathering chickens after ALV-J infection. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" }, { "database": "PubMed", "id": "34998433", "url": "https://glygen.org/publication/PubMed/34998433" } ] }, { "annotation": "Prlr expression in the skin did not show significant difference between early- (EF) and late-feathering (LF) phenotype chicks, while Spef2 expression displayed a significant difference between EF and LF chicks, suggesting that Spef2 may be a good candidate gene for chicken feathering. Moreover, dPrlr/dSpef2, the fusion gene, was also a good candidate gene as it was expressed only in LF chicks.", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" }, { "database": "PubMed", "id": "27081197", "url": "https://glygen.org/publication/PubMed/27081197" } ] }, { "annotation": "Study presents the causal mutation for feathering rate in turkey that causes a partial C-terminal loss of the prolactin receptor, and this truncated PRLR protein is strikingly similar to the protein encoded by the slow feathering K allele in chicken. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" }, { "database": "PubMed", "id": "29566646", "url": "https://glygen.org/publication/PubMed/29566646" } ] }, { "annotation": "This is a receptor for the anterior pituitary hormone prolactin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9#function" }, { "database": "UniProtKB", "id": "RU365035", "url": "https://www.uniprot.org/uniprotkb/RU365035#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRLR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9", "locus": { "chromosome": "Z", "start_pos": 11166761, "end_pos": 11188768, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014796", "url": "https://www.ensembl.org/id/ENSGALG00010014796" } ] } } ], "crossref": [ { "id": "A0A8V0YID9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YID9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003446", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003446", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395660", "url": "https://www.ncbi.nlm.nih.gov/gene/395660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANITCTW", "url": "https://omabrowser.org/oma/group/ANITCTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID9", "url": "https://www.orthodb.org/?gene=A0A8V0YID9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1170546", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1170546", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9020933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-982772", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-982772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUU9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQDLISSVQIILFLPLTTVGLAGQSFPGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSDPQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADANSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMRYVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELKKPINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKPEEGEEWETIFVGQQTQYKMFSLNPGKKYIIQIHCKPDHHGSWSEWSSENYIQIPNDFRVKDMIVWIVLGVLSSLICLIMSWTMVLKGYRMITFILPPVPGPKIKGIDTHLLETGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKITRKETDSDSGRGSCDSPSLLSEKCRETCALPSVLQTQEVRDVQEKKAAKRSWETQYVASERKALLSNSESAKSSTWPAVQLPNNQPPMFAYHSIVDAHKITLNTTNTNVAAVLVEDEEEHQSQCSLTETIPGEMEKQGEMENLHSKTEQTTAQVKQNRSNERLPFLDAALMDYVEVHKVIRQDEEPAVLLKHKENSGKIEKYTISGASKEYTKVSTVMDHNILVLMPDSRVPHTPASQEPAKETSQSLQQGQVEKNMSYCLTAPSDCKRETGGSEYMDPSSFMPSFK", "length": 831, "header": "tr|A0A8V0YID9-1|A0A8V0YID9_CHICK Isoform 1 of Prolactin receptor OS=Gallus gallus OX=9031 GN=PRLR PE=3 SV=1 CANONICAL=A0A8V0YID9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUU9/entry", "sequence": { "sequence": "MKQDLISSVQIILFLPLTTVGLAGQSFPGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSDPQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADANSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMRYVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGSGFCASDIFWNSTSNNIFKVEEGSPYTVGFYRLLWIVMAQRRTSL", "length": 316, "header": "tr|A0A1D5NUU9-1|A0A8V0YID9_CHICK Computationally mapped isoform of Prolactin receptor OS=Gallus gallus OX=9031 GN=PRLR PE=3 SV=2 CANONICAL=A0A8V0YID9-1" }, "locus": { "chromosome": "Z", "start_pos": 11188724, "end_pos": 11175460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035597.1", "url": "https://www.ensembl.org/id/ENSGALT00010035597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020668.1", "url": "https://www.ensembl.org/id/ENSGALP00010020668.1" } ] } }, { "isoform_ac": "A0A8V0YID9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9/entry", "sequence": { "sequence": "MKQDLISSVQIILFLPLTTVGLAGQSFPGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSDPQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADANSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMRYVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELKKPINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKPEEGEEWETIFVGQQTQYKMFSLNPGKKYIIQIHCKPDHHGSWSEWSSENYIQIPNDFRVKDMIVWIVLGVLSSLICLIMSWTMVLKGYRMITFILPPVPGPKIKGIDTHLLETGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKITRKETDSDSGRGSCDSPSLLSEKCRETCALPSVLQTQEVRDVQEKKAAKRSWETQYVASERKALLSNSESAKSSTWPAVQLPNNQPPMFAYHSIVDAHKITLNTTNTNVAAVLVEDEEEHQSQCSLTETIPGEMEKQGEMENLHSKTEQTTAQVKQNRSNERLPFLDAALMDYVEVHKVIRQDEEPAVLLKHKENSGKIEKYTISGASKEYTKVSTVMDHNILVLMPDSRVPHTPASQEPAKETSQSLQQGQVEKNMSYCLTAPSDCKRETGGSEYMDPSSFMPSFK", "length": 831, "header": "tr|A0A8V0YID9-1|A0A8V0YID9_CHICK Isoform 1 of Prolactin receptor OS=Gallus gallus OX=9031 GN=PRLR PE=3 SV=1 CANONICAL=A0A8V0YID9-1" }, "locus": { "chromosome": "Z", "start_pos": 11188724, "end_pos": 11167170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035607.1", "url": "https://www.ensembl.org/id/ENSGALT00010035607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020675.1", "url": "https://www.ensembl.org/id/ENSGALP00010020675.1" } ] } }, { "isoform_ac": "A0A8V0YRI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI7/entry", "sequence": { "sequence": "MKSGIVFLWRELGTGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKITRKETDSDSGRGSCDSPSLLSEKCRETCALPSVLQTQEVRDVQEKKAAKRSWETQYVASERKALLSNSESAKSSTWPAVQLPNNQPPMFAYHSIVDAHKITLNTTNTNVAAVLVEDEEEHQSQCSLTETIPGEMEKQGEMENLHSKTEQTTAQVKQNRSNERLPFLDAALMDYVEVHKVIRQDEEPAVLLKHKENSGKIEKYTISGASKEYTKVSTVMDHNILVLMPDSRVPHTPASQEPAKETSQSLQQGQVEKNMSYCLTAPSDCKRETGGSEYMDPSSFMPSFK", "length": 355, "header": "tr|A0A8V0YRI7-1|A0A8V0YID9_CHICK Computationally mapped isoform of Prolactin receptor OS=Gallus gallus OX=9031 GN=PRLR PE=3 SV=1 CANONICAL=A0A8V0YID9-1" }, "locus": { "chromosome": "Z", "start_pos": 11168408, "end_pos": 11167170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035583.1", "url": "https://www.ensembl.org/id/ENSGALT00010035583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020659.1", "url": "https://www.ensembl.org/id/ENSGALP00010020659.1" } ] } }, { "isoform_ac": "A0A8V0YRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ7/entry", "sequence": { "sequence": "MKQDLISSVQIILFLPLTTVGLAGQSFPGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSDPQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADANSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMRYVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGSGFCASDIFWNSTSNNIFKVEEGSPYTVGFYRLLWIVMAQWRITSSDC", "length": 319, "header": "tr|A0A8V0YRJ7-1|A0A8V0YID9_CHICK Computationally mapped isoform of Prolactin receptor OS=Gallus gallus OX=9031 GN=PRLR PE=3 SV=1 CANONICAL=A0A8V0YID9-1" }, "locus": { "chromosome": "Z", "start_pos": 11188724, "end_pos": 11176571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035612.1", "url": "https://www.ensembl.org/id/ENSGALT00010035612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020678.1", "url": "https://www.ensembl.org/id/ENSGALP00010020678.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of candidate genes for chicken early- and late-feathering.", "journal": "Poultry science", "date": "2016-07-01", "authors": "Zhao J, Yao J, Li F, Yang Z, Sun Z, Qu L, Wang K, Su Y, Zhang A, Montgomery S A, Geng T, Cui H", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ], "reference": [ { "type": "PubMed", "id": "27081197", "url": "https://glygen.org/publication/PubMed/27081197" } ] }, { "title": "Endogenous viral gene ev21 is not responsible for the expression of late feathering in chickens.", "journal": "Poultry science", "date": "2018-02-01", "authors": "Takenouchi A, Toshishige M, Ito N, Tsudzuki M", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ], "reference": [ { "type": "PubMed", "id": "29253229", "url": "https://glygen.org/publication/PubMed/29253229" } ] }, { "title": "Early and late feathering in turkey and chicken: same gene but different mutations.", "journal": "Genetics, selection, evolution : GSE", "date": "2018-03-22", "authors": "Derks Martijn F L, Herrero-Medrano Juan M, Crooijmans Richard P M A, Vereijken Addie, Long Julie A, Megens Hendrik-Jan, Groenen Martien A M", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ], "reference": [ { "type": "PubMed", "id": "29566646", "url": "https://glygen.org/publication/PubMed/29566646" } ] }, { "title": "dPRLR causes differences in immune responses between early and late feathering chickens after ALV-J infection.", "journal": "Veterinary research", "date": "2022-01-08", "authors": "Mo Guodong, Hu Bowen, Zhang Qihong, Ruan Zhuohao, Li Wangyu, Liang Jiaying, Shen Yizi, Mo Zhixin, Zhang Zihao, Wu Zhuyue, Shi Meiqing, Zhang Xiquan", "evidence": [ { "database": "RefSeq", "id": "NP_001384495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384495" } ], "reference": [ { "type": "PubMed", "id": "34998433", "url": "https://glygen.org/publication/PubMed/34998433" } ] } ], "pathway": [ { "id": "gga:395660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395660", "resource": "KEGG Pathway" }, { "id": "R-GGA-1170546", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1170546", "resource": "Reactome", "description": "Prolactin receptor signaling" }, { "id": "R-GGA-9020933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020933", "resource": "Reactome", "description": "Interleukin-23 signaling" }, { "id": "R-GGA-982772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-982772", "resource": "Reactome", "description": "Growth hormone receptor signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QET6-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKENVPSTVVFILLLFLNISLLNGQSPPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKTGGPNSCYFNKKHTSIWTIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPYLWIKWLPPTLVDVRSGWLTLQYEIRLQPEKTAEWETHFAGQQTQFKILSLYPGQKYLVQVRCKPDHGFWSEWPESSIQIPNDFSMKDTTMWIFVAILSAVVCLIMIWAVALKGYSMVACILPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDSEDQQLMPAHSKEHPSQGRKPTHLDPDSDSGRGSCDSPSLLSEKCDEPRANPPKFHTPEGIEKPGDPETNLPRPQDPQSTSVESKLLYFHADGSKSSTWPLPQPPILHDPGSSYHNLADVGQLVLGTAGATAALLEKTDRHAFNPPKTTETGGEGRATEQKESESFHSKTDQGTVWLLPQDKGPFVSPKPMEYVEIHKVSKDGALALLPKQQENGDRPEKAGAPETSKEYAQVSRVMDNHILVLVQDPRARNVAPFEEPTKETPPSRPQNPAAKDLASFTTAPGHCRHPLGGLDYLDPAGFMHSFQ", "length": 624 }, "evidence": [ { "id": "A0A8V0YID9", "url": "https://omabrowser.org/oma/group/A0A8V0YID9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FHZ0-1", "protein_name": "Prolactin receptor", "gene_name": "Prlr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKESMPSALAFILLFLNISLLNGQSPPGKPEIYKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTHECPDYETSGPNSCFFSKQYTSIWKIYVITVIATNQMGSSASDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWIKWSPPTITDVKTGWFTMEYEIRLKSEEADEWEVHFTGQQTHFKVFDLYPGQKYIVQTRCKPDHGYWSRWGQENSIEIPNDFTLKNTTMWIIVAVLSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLTALGCQDFPPTSDSEDLLVEFLEVDDNEDVQLMPSHSKEYPGQGVKPTHLDPDNDSGHGSYDSHSLLSEKCEEPQVYPPAFHIPEILEKPENPEANIPPTQDARSSTPYFHADVSKWSTWPLLPSQHMTRSPYHSIADVCKLAGGPVDTLASFLDKAGKNVLKFSKTLETEEEKVAEQEKKKSFHSETKQNTSWPLLQKNAPIVYAKPPDYVEIHKVNKDGVLSLFPKQKENDQVEKPGVPETSKEYTKVSGVMDDNILVLVPDSRAENTALFAESAKKVPPSLEQNQSAKDLASFAATSNNCRLQLGRLDYLDPTCFTHSFH", "length": 615 }, "evidence": [ { "id": "A0A8V0YID9", "url": "https://omabrowser.org/oma/group/A0A8V0YID9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABI0NV40-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"MPSALAFVLLVLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWSQESSVEMPNDFTLKDTTVWIIVAILSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVKPTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPTLHIPEITEKPENPEANIPPTVDPQSTNPNFHVDAPKSSTWPLLPGQHMPRSPYHSVADVCKLAGSPVNTLDSFLDKAEENVLKLSKALETGEEEVAEQKGAKSFPSDKQNTPWPLLQEKSPTVYVKPPDYVEIHKVNKDGVLSLFPKQRENNQTEKPGVPETSKEYAKVSGITDNNILVLVPDSRAQNTALLEESAKKAPPSFEADQSEKDLASFTATSSNRRLQLGRLDYLDPTCFMHSFH", "length": 610 }, "evidence": [ { "id": "A0A8V0YID9", "url": "https://omabrowser.org/oma/group/A0A8V0YID9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16471-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID9" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFH4-1", "uniprot_ac": "A0A8V0YFH4", "uniprot_id": "A0A8V0YFH4_CHICK", "mass": { "chemical_mass": 143619.0, "monoisotopic_mass": 143619.0 }, "refseq": { "ac": "XP_040554792", "name": "nik-related protein kinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792" }, "gene_names": [ { "name": "NRK", "type": "recommended", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "name": "MAP4K4", "type": "synonym", "evidence": [ { "id": "XP_040554792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792" } ] }, { "name": "NRK", "type": "synonym", "evidence": [ { "id": "XP_040554792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4/entry#names_and_taxonomy" } ] }, { "name": "nik-related protein kinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040554792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040554792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4", "locus": { "chromosome": "4", "start_pos": 17252839, "end_pos": 17147577, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012384", "url": "https://www.ensembl.org/id/ENSGALG00010012384" } ] } } ], "crossref": [ { "id": "A0A8V0YFH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008970", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008970", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06636", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06636", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422380", "url": "https://www.ncbi.nlm.nih.gov/gene/422380", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QPSLQWP", "url": "https://omabrowser.org/oma/group/QPSLQWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHW5", "url": "https://www.orthodb.org/?gene=A0A1D5PHW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y983", "url": "https://www.orthodb.org/?gene=A0A8V0Y983", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEA1", "url": "https://www.orthodb.org/?gene=A0A8V0YEA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFG1", "url": "https://www.orthodb.org/?gene=A0A8V0YFG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFH4", "url": "https://www.orthodb.org/?gene=A0A8V0YFH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK4", "url": "https://www.orthodb.org/?gene=A0A8V0YHK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC6", "url": "https://www.orthodb.org/?gene=A0A8V0YMC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040554792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554792", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PHW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y983", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y983-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGSQRAGSIPKGWRRPPKIQFLFFSFFLLSSKKGEAGGLGTPDVWLDLSNEDPAGIFELVQVVGNGTYGQVYKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1270, "header": "tr|A0A8V0YFH4-1|A0A8V0YFH4_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW5/entry", "sequence": { "sequence": "MARECAARSLDGIDLAALRDPAGIFELVQVVGNGTYGQVYKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKECDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1185, "header": "tr|A0A1D5PHW5-1|A0A8V0YFH4_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=2 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17155298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029673.1", "url": "https://www.ensembl.org/id/ENSGALT00010029673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017267.1", "url": "https://www.ensembl.org/id/ENSGALP00010017267.1" } ] } }, { "isoform_ac": "A0A8V0Y983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y983/entry", "sequence": { "sequence": "MSQKERIKWEYKHGPLLHCSQKHDQPQPTKHSKCRKDPAGIFELVQVVGNGTYGQVYKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1253, "header": "tr|A0A8V0Y983-1|A0A8V0YFH4_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17147686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029683.1", "url": "https://www.ensembl.org/id/ENSGALT00010029683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017272.1", "url": "https://www.ensembl.org/id/ENSGALP00010017272.1" } ] } }, { "isoform_ac": "A0A8V0YEA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA1/entry", "sequence": { "sequence": "MPVFVHHQPLKEASLVSRGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1213, "header": "tr|A0A8V0YEA1-1|A0A8V0YFH4_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17170685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029657.1", "url": "https://www.ensembl.org/id/ENSGALT00010029657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017256.1", "url": "https://www.ensembl.org/id/ENSGALP00010017256.1" } ] } }, { "isoform_ac": "A0A8V0YFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG1/entry", "sequence": { "sequence": "SVGYQEKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVGKVIFVLSLDSCLIIPLHPMPLVFFFSYSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1196, "header": "tr|A0A8V0YFG1-1|A0A8V0YFG1_CHICK Computationally mapped isoform of Nik related kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17181301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029653.1", "url": "https://www.ensembl.org/id/ENSGALT00010029653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017254.1", "url": "https://www.ensembl.org/id/ENSGALP00010017254.1" } ] } }, { "isoform_ac": "A0A8V0YFH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4/entry", "sequence": { "sequence": "MSDGSQRAGSIPKGWRRPPKIQFLFFSFFLLSSKKGEAGGLGTPDVWLDLSNEDPAGIFELVQVVGNGTYGQVYKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1270, "header": "tr|A0A8V0YFH4-1|A0A8V0YFH4_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17150818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029677.1", "url": "https://www.ensembl.org/id/ENSGALT00010029677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017269.1", "url": "https://www.ensembl.org/id/ENSGALP00010017269.1" } ] } }, { "isoform_ac": "A0A8V0YHK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK4/entry", "sequence": { "sequence": "MARECAARSLDGIDLAALRDPAGIFELVQVVGNGTYGQVYKGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEVCEPVSVAGVISQYQSKELGLAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1257, "header": "tr|A0A8V0YHK4-1|A0A8V0YHK4_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17155298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029666.1", "url": "https://www.ensembl.org/id/ENSGALT00010029666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017260.1", "url": "https://www.ensembl.org/id/ENSGALP00010017260.1" } ] } }, { "isoform_ac": "A0A8V0YMC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC6/entry", "sequence": { "sequence": "MVILCQPWCRTVSAVALSVLVCLVGRHVKTGQLAAIKVMNVTENEEEEIKLEINMLKKYSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLVKKTKGNCFKEDWIAYICREVLRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEENPDSTYDYRSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSRKWSKKFLNFVESCLVKNYLHRPSTETLLKHSFIRDMQNERQVRIMLKDHLDRTRKKKGEKEETDYDYSGSEEEDDELNEDEGEPSSIVNLPGESTLRREFLRLQQENKNRSDPQRQQQQLKDQEKYKKQLLTERQKRIEQQKEQRRRLEDHQRREQELRRQQECDQRWTEANDVQRREERCKEDKRAVEDDERFIADGQRKSEKKQKKVEDVQHNKKGHRTLPKDQTQLLSLQHDHKQKKKEPSKSSSSAAHLPSSNTTKEAEGQRKRSDGIQPALQWPAALGHDVMPQAKVGSGSSSSPCTPALQRAVLVQCDNFQASKDVYHSSSLSDMVTTLVSLGQDDVFWSGNQSEEQPPKVPERTTSKFYSRDQPGQQRCHSSNSHQLSPGGHALKLNSSSSSTAGNKPWEMASHQNSRSTSGNPGPAKGENALSQNHIQLHKKPEKVSHLGQMASPCSFAKGKDSANLFLKAADYSSSSDEVSSSDEDDTNHTRQLLSSRVADFSRTRVPDGIELKPQSTIAEQKDQVLGKQISSTQEGLWNINNQNYLLPDLLQQSQISNAAVNPPKVPLTNQEPQNKSLSKTPSTESTPSKSSTSSTTSFTSFIDPRLLPITPPTSPVGPPCSSPSSAKPEPVRRENARKGSVVNVNPTNIRPQSDSPEIRKYKKKFNSEVICAALWGVNLLVGTENGLWLLDRSGQGRVYSLITRRRFQQMDVLEGLNVLITISGKKNKLRVYYLSWLRNKILRNDPEVEKRQGWVSVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFTSLHHKPLSVDLTVENGQRLKVIYGSLVGFHAIDVDSGSVYDLYLPTHIQGAIRPHAIIILPNTSGMELLLAYEDEGIYIDIYGHFTKETVLQWGEMPASVAYLQSNQVMGWGEKAIELRSVETGNLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNVLFNW", "length": 1219, "header": "tr|A0A8V0YMC6-1|A0A8V0YMC6_CHICK Computationally mapped isoform of Nik related kinase OS=Gallus gallus OX=9031 GN=NRK PE=3 SV=1 CANONICAL=A0A8V0YFH4-1" }, "locus": { "chromosome": "4", "start_pos": 17249227, "end_pos": 17161865, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029662.1", "url": "https://www.ensembl.org/id/ENSGALT00010029662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017258.1", "url": "https://www.ensembl.org/id/ENSGALP00010017258.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 877, "start_aa": "Thr", "end_pos": 877, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr877", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 901, "start_aa": "Thr", "end_pos": 901, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr901", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1158, "end_pos": 1160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", 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"https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { 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"uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { 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"ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", 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"https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ] } ], "protein_names": [ { "name": "Decorin", "type": "recommended", "evidence": [ { "id": "A0A8V0YJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May affect the rate of fibrils formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8#function" }, { "database": "UniProtKB", "id": "PIRNR002490", "url": "https://www.uniprot.org/uniprotkb/PIRNR002490#function" }, { "database": "UniProtKB", "id": "RU364097", "url": "https://www.uniprot.org/uniprotkb/RU364097#function" }, { "database": "UniProtKB", "id": "A0A1L1RX77", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX77#function" }, { "database": "UniProtKB", "id": "ARBA00004025", "url": "https://www.uniprot.org/uniprotkb/ARBA00004025#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8", "locus": { "chromosome": "1", "start_pos": 44073194, "end_pos": 44224274, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013345", "url": "https://www.ensembl.org/id/ENSGALG00010013345" } ] } } ], "crossref": [ { "id": "A0A8V0YJB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011274", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011274", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FRCIYER", "url": "https://omabrowser.org/oma/group/FRCIYER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RX77", "url": "https://www.orthodb.org/?gene=A0A1L1RX77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJB8", "url": "https://www.orthodb.org/?gene=A0A8V0YJB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1971475", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971475", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022923", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022923", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RX77", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RX77-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLVLLFVLLLPVCLATPFHQKGLFDFMIEDEGSADMAPTDDPVISGFGPVCPFRCQCHLRVVQCSDLDLRTPRVPSQCSFCRCDLGVCVLLEATSDNSLERVPKDLPPDTTLLDLQNNKITEIKEGDFKNLKNLHALILVNNKISKISPAAFAPLKKLERLYLSKNNLKELPENMPKSLQEIRAHENEISKLRKAVFNGLNQVIVLELGTNPLKSSGIENGAFQGMKRLSYIRIADTNITSIPKGLPPSLTELHLDGNKISKIDAEGLSGLTNLAKLGLSFNSISSVENGSLNNVPHLRELHLNNNELVRVPSGLGEHKYIQVVYLHNNKIASIGINDFCPLGYNTKKATYSGVSLFSNPVQYWEIQPSAFRCIHERSAVQIGNYK", "length": 387, "header": "tr|A0A8V0YJB8-1|A0A8V0YJB8_CHICK Isoform 1 of Decorin OS=Gallus gallus OX=9031 GN=DCN PE=3 SV=1 CANONICAL=A0A8V0YJB8-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RX77-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX77/entry", "sequence": { "sequence": "MRLVLLFVLLLPVCLATPFHQKGLFDFMIEDEGSADMAPTDDPVISGFGPVCPFRCQCHLRVVQCSDLGLERVPKDLPPDTTLLDLQNNKITEIKEGDFKNLKNLHALILVNNKISKISPAAFAPLKKLERLYLSKNNLKELPENMPKSLQEIRAHENEISKLRKAVFNGLNQVIVLELGTNPLKSSGIENGAFQGMKRLSYIRIADTNITSIPKGLPPSLTELHLDGNKISKIDAEGLSGLTNLAKLGLSFNSISSVENGSLNNVPHLRELHLNNNELVRVPSGLGEHKYIQVVYLHNNKIASIGINDFCPLGYNTKKATYSGVSLFSNPVQYWEIQPSAFRCIHERSAVQIGNYK", "length": 357, "header": "tr|A0A1L1RX77-1|A0A8V0YJB8_CHICK Computationally mapped isoform of Decorin OS=Gallus gallus OX=9031 GN=DCN PE=3 SV=2 CANONICAL=A0A8V0YJB8-1" }, "locus": { "chromosome": "1", "start_pos": 44108131, "end_pos": 44074519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032123.1", "url": "https://www.ensembl.org/id/ENSGALT00010032123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018913.1", "url": "https://www.ensembl.org/id/ENSGALP00010018913.1" } ] } }, { "isoform_ac": "A0A8V0YJB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8/entry", "sequence": { "sequence": "MRLVLLFVLLLPVCLATPFHQKGLFDFMIEDEGSADMAPTDDPVISGFGPVCPFRCQCHLRVVQCSDLDLRTPRVPSQCSFCRCDLGVCVLLEATSDNSLERVPKDLPPDTTLLDLQNNKITEIKEGDFKNLKNLHALILVNNKISKISPAAFAPLKKLERLYLSKNNLKELPENMPKSLQEIRAHENEISKLRKAVFNGLNQVIVLELGTNPLKSSGIENGAFQGMKRLSYIRIADTNITSIPKGLPPSLTELHLDGNKISKIDAEGLSGLTNLAKLGLSFNSISSVENGSLNNVPHLRELHLNNNELVRVPSGLGEHKYIQVVYLHNNKIASIGINDFCPLGYNTKKATYSGVSLFSNPVQYWEIQPSAFRCIHERSAVQIGNYK", "length": 387, "header": "tr|A0A8V0YJB8-1|A0A8V0YJB8_CHICK Isoform 1 of Decorin OS=Gallus gallus OX=9031 GN=DCN PE=3 SV=1 CANONICAL=A0A8V0YJB8-1" }, "locus": { "chromosome": "1", "start_pos": 44108131, "end_pos": 44074519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032122.1", "url": "https://www.ensembl.org/id/ENSGALT00010032122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018912.1", "url": "https://www.ensembl.org/id/ENSGALP00010018912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" }, { "id": "R-GGA-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" }, { "id": "R-GGA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" }, { "id": "R-GGA-2022923", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022923", "resource": "Reactome", "description": "DS-GAG biosynthesis" }, { "id": "R-GGA-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "resource": "Reactome", "description": "CS/DS degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HJG6-1", "protein_name": "Decorin", "gene_name": "Dcn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKATLIFLLLAQVSWAGPFEQRGLFDFMLEDEASGVGPEDSGFPPDLPHLEPLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHTLILVNNKINKISSGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEISKVRKTVFNGLNQMIVIELGTNPLKSSGIESGAFQGMKRLSYIRIADTNITAIPQGLPPSLTELHLDGNKITKVDASSLKGLTNLAKLGLSFNSISAIDNGTLANTPHLRELHLDNNKLIRVPGGLAEHKYIQVVYLHNNNISAVGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK", "length": 362 }, "evidence": [ { "id": "A0A8V0YJB8", "url": "https://omabrowser.org/oma/group/A0A8V0YJB8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P07585-1", "protein_name": "Decorin", "gene_name": "DCN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK", "length": 359 }, "evidence": [ { "id": "A0A8V0YJB8", "url": "https://omabrowser.org/oma/group/A0A8V0YJB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21793-1", "protein_name": "Decorin", "gene_name": "DCN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKATIIFLLVAQVSWAGPFQQKGLFDFMLEDEASGIGPEEHFPEVPEIEPMGPVCPFRCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISAIGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRAAVQLGNYK", "length": 360 }, "evidence": [ { "id": "A0A8V0YJB8", "url": "https://omabrowser.org/oma/group/A0A8V0YJB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P28654-1", "protein_name": "Decorin", "gene_name": "Dcn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKATLIFFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPVRYWEIFPNTFRCVYVRSAIQLGNYK", "length": 354 }, "evidence": [ { "id": "A0A8V0YJB8", "url": "https://omabrowser.org/oma/group/A0A8V0YJB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01129-1", "protein_name": "Decorin", "gene_name": "Dcn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKATLVLFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKSVFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHLDGNKIAKVDAASLKGMSNLSKLGLSFNSITVVENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYVQVVYLHNNNISEVGQHDFCLPSYQTRKTSYTAVSLYSNPVRYWQIHPHTFRCVFGRSTIQLGNYK", "length": 354 }, "evidence": [ { "id": "A0A8V0YJB8", "url": "https://omabrowser.org/oma/group/A0A8V0YJB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix binding", "id": "GO:0050840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJB8" }, { "id": "PF01462", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 77, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFD5-1", "uniprot_ac": "A0A8V0YFD5", "uniprot_id": "A0A8V0YFD5_CHICK", "mass": { "chemical_mass": 23831.0, "monoisotopic_mass": 23831.0 }, "refseq": {}, "gene_names": [ { "name": "POLR3H", "type": "recommended", "evidence": [ { "id": "A0A8V0YFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase subunit", "type": "recommended", "evidence": [ { "id": "A0A8V0YFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With CRCP/RPC9 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZW5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZW5#function" }, { "database": "UniProtKB", "id": "ARBA00054245", "url": "https://www.uniprot.org/uniprotkb/ARBA00054245#function" }, { "database": "UniProtKB", "id": "A0A8V0Y278", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y278#function" }, { "database": "UniProtKB", "id": "A0A8V0YFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5#function" } ] }, { "annotation": "DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZW5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZW5#function" }, { "database": "UniProtKB", "id": "RU369086", "url": "https://www.uniprot.org/uniprotkb/RU369086#function" }, { "database": "UniProtKB", "id": "A0A8V0Y278", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y278#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H3#function" }, { "database": "UniProtKB", "id": "A0A8V0YFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLR3H", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5", "locus": { "chromosome": "1", "start_pos": 49646054, "end_pos": 49639688, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010891", "url": "https://www.ensembl.org/id/ENSGALG00010010891" } ] } } ], "crossref": [ { "id": "A0A8V0YFD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011947", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011947", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZW5", "url": "https://www.orthodb.org/?gene=A0A1L1RZW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y278", "url": "https://www.orthodb.org/?gene=A0A8V0Y278", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8H3", "url": "https://www.orthodb.org/?gene=A0A8V0Y8H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFD5", "url": "https://www.orthodb.org/?gene=A0A8V0YFD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12709:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12709:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RZW5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y278", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y278", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y278-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y278-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVLVEMTDTVRIPPWQFERKLNESIAEELNKKLANKVVYNVGLCICLYDITKLEDSYIFPGDGASHTKVHFRYVVFHPFLDEILVGEIKSCSQDGVHVSIGFFDDIVIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDIGEEIRFRVVDETFVDTSPTGPSSAEASTSNATEEVQKKEAPYTLVVTMCIIPIVSQSQWLILFLK", "length": 209, "header": "tr|A0A8V0YFD5-1|A0A8V0YFD5_CHICK Isoform 1 of DNA-directed RNA polymerase subunit OS=Gallus gallus OX=9031 GN=POLR3H PE=3 SV=1 CANONICAL=A0A8V0YFD5-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZW5/entry", "sequence": { "sequence": "MLVTKAAPARLCSLPVSPEAAMFVLVEMTDTVRIPPWQFERKLNESIAEELNKKLANKVVYNVGLCICLYDITKLEDSYIFPGDGASHTKVHFRYVVFHPFLDEILVGEIKSCSQDGVHVSIGFFDDIVIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDIGEEIRFRVVDETFVDTSPTGPSSAEASTSNATEEVQKKEAPYTLVGSISEPGLGLLSWWTNS", "length": 227, "header": "tr|A0A1L1RZW5-1|A0A8V0YFD5_CHICK Computationally mapped isoform of DNA-directed RNA polymerase subunit OS=Gallus gallus OX=9031 GN=POLR3H PE=3 SV=2 CANONICAL=A0A8V0YFD5-1" }, "locus": { "chromosome": "1", "start_pos": 49645235, "end_pos": 49639974, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026059.1", "url": "https://www.ensembl.org/id/ENSGALT00010026059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014699.1", "url": "https://www.ensembl.org/id/ENSGALP00010014699.1" } ] } }, { "isoform_ac": "A0A8V0Y278-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y278/entry", "sequence": { "sequence": "MFVLVEMTDTVRIPPWQFERKLNESIAEELNKKLANKVVYNVGLCICLYDITKLEDSYIFPGDGASHTKVHFRYVVFHPFLDEILVGEIKSCSQDGVHVSIGFFDDIVIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDIGEEIRFRVVDETFVDTSPTGPSSAEASTSNATEEVQKKEAPYTLVGSISEPVLTGTGEETAKDWS", "length": 209, "header": "tr|A0A8V0Y278-1|A0A8V0YFD5_CHICK Computationally mapped isoform of DNA-directed RNA polymerase subunit OS=Gallus gallus OX=9031 GN=POLR3H PE=3 SV=1 CANONICAL=A0A8V0YFD5-1" }, "locus": { "chromosome": "1", "start_pos": 49645686, "end_pos": 49640037, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026055.1", "url": "https://www.ensembl.org/id/ENSGALT00010026055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014695.1", "url": "https://www.ensembl.org/id/ENSGALP00010014695.1" } ] } }, { "isoform_ac": "A0A8V0Y8H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H3/entry", "sequence": { "sequence": "MFVLVEMTDTVRIPPWQFERKLNESIAEELNKKLANKVVYNVGLCICLYDITKLEDSYIFPGDGASHTKVHFRYVVFHPFLDEILVGEIKSCSQDGVHALGVASDEAEQVWVWEYETEEGAHDLYMDIGEEIRFRVVDETFVDTSPTGPSSAEASTSNATEEVQKKEAPYTLVGSISEPGLGLLSWWTNS", "length": 190, "header": "tr|A0A8V0Y8H3-1|A0A8V0YFD5_CHICK Computationally mapped isoform of DNA-directed RNA polymerase subunit OS=Gallus gallus OX=9031 GN=POLR3H PE=3 SV=1 CANONICAL=A0A8V0YFD5-1" }, "locus": { "chromosome": "1", "start_pos": 49645235, "end_pos": 49640037, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026062.1", "url": "https://www.ensembl.org/id/ENSGALT00010026062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014702.1", "url": "https://www.ensembl.org/id/ENSGALP00010014702.1" } ] } }, { "isoform_ac": "A0A8V0YFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD5/entry", "sequence": { "sequence": 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"id": "A0A8V0YFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAVEPNGGTPRRRPLSFCPCCAHEGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2261, "header": "tr|A0A8V0YI48-1|A0A8V0YI48_CHICK Isoform 1 of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TTZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTZ5/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAVEPNGGTPRRRPLSFCPCCAHEGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2229, "header": "tr|A0A3Q2TTZ5-1|A0A8V0YI48_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030048.1", "url": "https://www.ensembl.org/id/ENSGALT00010030048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017461.1", "url": "https://www.ensembl.org/id/ENSGALP00010017461.1" } ] } }, { "isoform_ac": "A0A3Q2U3Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Z6/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEADYWGESYYSDLIDLHLGGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2224, "header": "tr|A0A3Q2U3Z6-1|A0A8V0YI48_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030067.1", "url": "https://www.ensembl.org/id/ENSGALT00010030067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017469.1", "url": "https://www.ensembl.org/id/ENSGALP00010017469.1" } ] } }, { "isoform_ac": "A0A8V0YF07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF07/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2081, "header": "tr|A0A8V0YF07-1|A0A8V0YI48_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030121.1", "url": "https://www.ensembl.org/id/ENSGALT00010030121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017496.1", "url": "https://www.ensembl.org/id/ENSGALP00010017496.1" } ] } }, { "isoform_ac": "A0A8V0YF13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF13/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRESIYVPHALAFKRSYSSKRAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2180, "header": "tr|A0A8V0YF13-1|A0A8V0YF13_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030131.1", "url": "https://www.ensembl.org/id/ENSGALT00010030131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017501.1", "url": "https://www.ensembl.org/id/ENSGALP00010017501.1" } ] } }, { "isoform_ac": "A0A8V0YFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ9/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2142, "header": "tr|A0A8V0YFZ9-1|A0A8V0YFZ9_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030033.1", "url": "https://www.ensembl.org/id/ENSGALT00010030033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017454.1", "url": "https://www.ensembl.org/id/ENSGALP00010017454.1" } ] } }, { "isoform_ac": "A0A8V0YI03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI03/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEADYWGESYYSDLIDLHLGGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2047, "header": "tr|A0A8V0YI03-1|A0A8V0YI03_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029986.1", "url": "https://www.ensembl.org/id/ENSGALT00010029986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017430.1", "url": "https://www.ensembl.org/id/ENSGALP00010017430.1" } ] } }, { "isoform_ac": "A0A8V0YI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAVEPNGGTPRRRPLSFCPCCAHEGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2261, "header": "tr|A0A8V0YI48-1|A0A8V0YI48_CHICK Isoform 1 of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030080.1", "url": "https://www.ensembl.org/id/ENSGALT00010030080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017475.1", "url": "https://www.ensembl.org/id/ENSGALP00010017475.1" } ] } }, { "isoform_ac": "A0A8V0YI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI62/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEEGEYCPWEKELQQGLWLQRLSNEEDTGTFKAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRESIYVPHALAFKRSYSSKRAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2224, "header": "tr|A0A8V0YI62-1|A0A8V0YI62_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030107.1", "url": "https://www.ensembl.org/id/ENSGALT00010030107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017490.1", "url": "https://www.ensembl.org/id/ENSGALP00010017490.1" } ] } }, { "isoform_ac": "A0A8V0YMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU7/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEVPQCGSLEPEFIRGEPKCLTAAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAVEPNGGTPRRRPLSFCPCCAHEGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2252, "header": "tr|A0A8V0YMU7-1|A0A8V0YMU7_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030016.1", "url": "https://www.ensembl.org/id/ENSGALT00010030016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017448.1", "url": "https://www.ensembl.org/id/ENSGALP00010017448.1" } ] } }, { "isoform_ac": "A0A8V0YMY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY5/entry", "sequence": { "sequence": "MEESKNEKVNQAHVLFDRFVQASTCKGTLKAFQELCDYLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACANTKCLIIGAGPCGLRTAIDLSFLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILLKVALILGIEIHVNVEFQGLVYPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVIRHDYADTELLLSRENVDQEALLNYAREAADFSTNQQLPSLDFAINHYGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGASPLEVLAERESIYRLLPQTTPENVSKNFSHYSIDPATRYPNINVNFLRPQQVRHLYNTGDLKDIHLEIENFVNSRTPKLTRNESVARSSKLLSWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEHNVEKNNQLAFDIAEKEFGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDTIPSSDSVDLNAEEKAALIASTKSPISFLSKLGQSISRKRTPKDKKEKELDGAGKRRKTSQSEDEDVPRSYREERPTLVSALTERRIDAAIGNQNKVKSMATQLLAKFEENAPVQSSTLRRQQPVLPYQERVHNQPSSRREQGRLAPIPQWKQMRSKERSRTCPKKVIMLSSSTPPSSPPYPRLQRYREPGAGYPGEQSPRQERRSPRLFSDDQVPENVEQRACQLAALLEPRPAARHQPETEPSRRFFVDQWELSLSLRSSNRPSSPSSDSLRQKYIKMYTGGVSSLAEQIANQLQRKEQPKTLLDKKELGSLKKEFPQNLGGSDVCYFCRKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSSYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVSGKDTKGPLQDTMASDGSGRANSISSSAERAPGPNVNGLEEPSLAKRLRGTPERIELENYRLSLQREEELEEVPEETLAEHNLSSVLDKGAEEDVPSSSSESEMEEEDEDEDDELLLPQQPPSDLGGVPWKEAVRIHALLKGKSEEEIEAEENHEYDDKEEDEEEEDDEEYEEESSEVPQCGSLEPEFIRGEPKCLTAAGNLRLQQIVNPVDPLEILADVHWTHIREKEEEEKMVPASKSSTSRASDLPSVRHEAVQAWLETVPGASCEDNGVEDELGTEPADTEGQAGEEGDTGAELDDDDIPSDAEAEYRLHRSNVEEPGLKVSEDEEGAEDASCSVSEDPCKASAPNQSTNDIVLPLSPADSLKAEQVEDVKDPLAAVKSPEARFFPELFLLEEGPKDDIPKDRKAKSPSVPLSPVLSQPVASPETTAPTSPAESQPAAPKLASSPTSSQKPICSQPLPSAETSIPSPVEPPVCFQPGPALTSTPLAKLVLRNQDSEVEKLGSPTTAEEALKRSNLVEEFWMKSAEIRRSLGLTPVDRNKRSESNFPVSALETTPLKTFNSESVAGDERMHLVKPQPAPRRQGLSKLENEQISLLTPKSPSEKELRSSHEVKRDVSSSSGLGLQESSSNMRTLASQSFNTSDSTMLTPPSSPPPPPPQDEEPATLRRKRYQALWQNEVESKSPPTPASTPPVPPRHEPTSAAKEPTQAKKDDVRKSFAESVDEIPFADDVEDTYDDRTEDSSLHEKFFTPPTSRPRLEKPLVLPLVKENGGPPSMEGGVNQKKRVLPEISAEAKELAEERMRAREKSVKSQALRDAMAKQLCKMKDMEMAAAAGATRARKASSMPLKTKELFHDSPKHLALKIAEGSTLKHDAASEKFSTPAADVAGPEGSVTSSEGSSGKSKKRTSLFSPRKNKKEKKSKNDSRLSDKSSGGTEEATKSRSLWKSVFSGYKKDKKKKADDKSCPSTPSSSATVDSGKHKASPFITAADLQLRRHLSFSEDSDLSSDDVLERSSQKSKRERAYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTDEELSEEKRILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFSLNWS", "length": 2230, "header": "tr|A0A8V0YMY5-1|A0A8V0YMY5_CHICK Computationally mapped isoform of F-actin monooxygenase OS=Gallus gallus OX=9031 GN=MICAL3 PE=3 SV=1 CANONICAL=A0A8V0YI48-1" }, "locus": { "chromosome": "1", "start_pos": 62026259, "end_pos": 61926726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030093.1", "url": "https://www.ensembl.org/id/ENSGALT00010030093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017483.1", "url": "https://www.ensembl.org/id/ENSGALP00010017483.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1718, "start_aa": "Thr", "end_pos": 1718, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1718", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2000, "start_aa": "Thr", "end_pos": 2000, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2000", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "F-actin monooxygenase activity", "id": "GO:0120501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen", "id": "GO:0016709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1380, "end_pos": 1382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1672, "end_pos": 1674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1955, "end_pos": 1957, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2259, "end_pos": 2261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51308", "name": "", "equation": "L-methionyl-[F-actin] + NADPH + O2 + H(+) = L-methionyl-(R)-S-oxide-[F-actin] + NADP(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZN88-1", "A0A8V0YI48-1" ], "evidence": [ { "id": "51308", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51308" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YI48", "gene_name": "MICAL3", "activity": [ { "ec_number": "1.14.13.225", "activity": "L-methionyl(47)-[F-actin] + NADPH + O2 + H(+) = L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+) + H2O.", "evidence": [ { "id": "A0A8V0YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ] }, { "ec_number": "1.14.13.225", "activity": "", "evidence": [ { "id": "A0A8V0YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" } ] } ] }, { "uniprot_ac": "A0A8V0ZN88", "gene_name": "MICAL2", "activity": [ { "ec_number": "1.14.13.225", "activity": "L-methionyl(47)-[F-actin] + NADPH + O2 + H(+) = L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+) + H2O.", "evidence": [ { "id": "A0A8V0ZN88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN88" } ] }, { "ec_number": "1.14.13.225", "activity": "", "evidence": [ { "id": "A0A8V0ZN88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN88" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" }, { "id": "PS51848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BMERB", "eco_id": "ECO_0000259", "start_pos": 2078, "end_pos": 2249, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 517, "end_pos": 623, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI48" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 950, "end_pos": 1012, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.13.225", "ec_name": "L-methionyl(47)-[F-actin] + NADPH + O2 + H(+) = L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+) + H2O.", "evidence": [ { "id": "1.14.13.225", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.225" }, { "id": "1.14.13.225", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.13.225" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1718, 2000 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1103, "end_pos": 1105 }, { "start_pos": 1380, "end_pos": 1382 }, { "start_pos": 1672, "end_pos": 1674 }, { "start_pos": 1955, "end_pos": 1957 }, { "start_pos": 2259, "end_pos": 2261 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 538, "end_pos": 540 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YG16-1", "uniprot_ac": "A0A8V0YG16", "uniprot_id": "A0A8V0YG16_CHICK", "mass": { "chemical_mass": 82859.0, "monoisotopic_mass": 82859.0 }, "refseq": {}, "gene_names": [ { "name": "MARCHF7", "type": "recommended", "evidence": [ { "id": "A0A8V0YG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MARCHF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16", "locus": { "chromosome": "7", "start_pos": 36319993, "end_pos": 36294652, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010987", "url": "https://www.ensembl.org/id/ENSGALG00010010987" } ] } } ], "crossref": [ { "id": "A0A8V0YG16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012584", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16812", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16812", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424332", "url": "https://www.ncbi.nlm.nih.gov/gene/424332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424332", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMMSGNR", "url": "https://omabrowser.org/oma/group/RMMSGNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U0H6", "url": "https://www.orthodb.org/?gene=A0A3Q2U0H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2X0", "url": "https://www.orthodb.org/?gene=A0A8V0Y2X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7L3", "url": "https://www.orthodb.org/?gene=A0A8V0Y7L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7L8", "url": "https://www.orthodb.org/?gene=A0A8V0Y7L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG16", "url": "https://www.orthodb.org/?gene=A0A8V0YG16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG25", "url": "https://www.orthodb.org/?gene=A0A8V0YG25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14471", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14471", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14471:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14471:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U0H6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRFINLARTLQAHMEDIESRCFPSSPPSLSHWT", "length": 748, "header": "tr|A0A8V0YG16-1|A0A8V0YG16_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U0H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0H6/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRFINLARTLQAHMEDIETSEDDSED", "length": 741, "header": "tr|A0A3Q2U0H6-1|A0A8V0YG16_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36319059, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026332.1", "url": "https://www.ensembl.org/id/ENSGALT00010026332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014956.1", "url": "https://www.ensembl.org/id/ENSGALP00010014956.1" } ] } }, { "isoform_ac": "A0A8V0Y2X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X0/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRLLRMILKTDAGITFMLKETEVLQKC", "length": 742, "header": "tr|A0A8V0Y2X0-1|A0A8V0YG16_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36319111, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026329.1", "url": "https://www.ensembl.org/id/ENSGALT00010026329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014953.1", "url": "https://www.ensembl.org/id/ENSGALP00010014953.1" } ] } }, { "isoform_ac": "A0A8V0Y7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L3/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRFINLARTLQAHMEDIESRCFPSSPPSLSHWT", "length": 693, "header": "tr|A0A8V0Y7L3-1|A0A8V0YG16_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36317232, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026323.1", "url": "https://www.ensembl.org/id/ENSGALT00010026323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014947.1", "url": "https://www.ensembl.org/id/ENSGALP00010014947.1" } ] } }, { "isoform_ac": "A0A8V0Y7L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7L8/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRFINLARTLQAHMEDIETSEDDSED", "length": 688, "header": "tr|A0A8V0Y7L8-1|A0A8V0YG16_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36319059, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026328.1", "url": "https://www.ensembl.org/id/ENSGALT00010026328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014952.1", "url": "https://www.ensembl.org/id/ENSGALP00010014952.1" } ] } }, { "isoform_ac": "A0A8V0YG16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQADYEFISSGLYLVVLLHLCEQRFSDMLGTASEASTRVRFINLARTLQAHMEDIESRCFPSSPPSLSHWT", "length": 748, "header": "tr|A0A8V0YG16-1|A0A8V0YG16_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36317232, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026325.1", "url": "https://www.ensembl.org/id/ENSGALT00010026325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014949.1", "url": "https://www.ensembl.org/id/ENSGALP00010014949.1" } ] } }, { "isoform_ac": "A0A8V0YG25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG25/entry", "sequence": { "sequence": "MESKPSRIPRRISVQAPSSTLGSRTLTGNSLAGAYSARDSSRRLDSGYQESDVLSSSDRDWGIGERETHENPWKLTTSSSTHYSGTLDHPRSGRFLGTRNRLSTSSSSHFTSGCYDDSERTQGAYSRLHSQQQDSDSKRPKLSCTSTSSVRSNGLTAFSDSSWRYSRIPRSSSVMFGSLGTELVRERRELERTDQSFNNLVDHSYRNSDFSSSAYFQDRPASTYAEGARPKENSLSALRLNASMNHQLPSGHQTSFFNRDSNIRSSRTSYSSRQRRNEIESPQRNIHPAFSHSTTRGETSSSSSERVFSSQRSLNDAAADTEGRRTTRQLLSRLASSMSSTFFSRRSSQDSLQTRSLGSEESSLVPRVQASTLSSTNGAATPEAPGLHTSEASQGFSFLRRRWGLSGVSQSLNTDSDGESYRPDSESRSTGSWLSSSLRNRCTPLFSRRRREGRDESARISTSDAAARSQHVLRRRESGEETSLEASDGPPRASVSRPPTPAVSGIPTATASPPDSAHNRRSSGILPSSLFRFSVPPTLGSSLSDNLMITVDIIPSGWSQSDGQESDKSKIPPSRDPERLQKIKESLLLEDSEDEEGDLCRICQMSSASTDNNLIEPCKCTGSLQYVHQECMKKWLQSKINSGSSLEAVTTCELCKEKLHLNLEDFDIHELYRAHANEQTMNLSALVSTLWCCYTYVSSAFLICLEPQVRPAHVSDLLTLQELFRHIWKILKLLRMILKTDAGITFMLKETEVLQKC", "length": 757, "header": "tr|A0A8V0YG25-1|A0A8V0YG25_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF7 PE=4 SV=1 CANONICAL=A0A8V0YG16-1" }, "locus": { "chromosome": "7", "start_pos": 36319111, "end_pos": 36299788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026335.1", "url": "https://www.ensembl.org/id/ENSGALT00010026335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014959.1", "url": "https://www.ensembl.org/id/ENSGALP00010014959.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 500, "start_aa": "Thr", "end_pos": 500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr500", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424332", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NG75-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "marchf7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSKSRRFPFAVSSSSSLSSPSSLSSSSSALSASRLYGRGSVLGRDRFSRDASVKLDSDYQGSRLLSSPRVYSSTESRHSNWKLSTPVTSSSSSSSSCDRSWTESSSGDRARLTDSERRLGTYCGLLGTSQDSESKRAKLSYTNREVYSRSPSTSKPATSYSTLGSSWKSSISPLSRSSSSSSSSSVSTQSEGLWARRDLEKRVDSGLSSLGESSYRPSSLTSSLYRSERVASTYAQGARPKDSQYSSHRENSSSSRRIPSEYIPSPLERNSQRLTSDYQSNLFPRDTPRSSSTRTSTSVSDTSHHSSWSSTPYTALSACTSSPPSISPAPTPLPAQNTGESDGRGTTRRLLSRLFSRRSSQESNSTASTASDSRSYDSSPDEAPPTEAPPPISRENLEAELRNSDPAQAFSFLRRRGPSLAPVQESTDVEPEQESLRPPAGLSWLNWNRCTPLFSRRRREGRDESARMDPHRSPQFSLGDRDGRKTPDQGTHCEDDDDEDDDDEDESSEGAAAGPSSGASALSASLLQDGAHLAGRSHGMGRGMNSPLFRLPENVLIGVGVEGRSQADEQPKDKPAPSRDPERLRKIQESLLLEESDEEEGDLCRICQMGEQWSSNPLIEPCKCTGSLQYVHQDCIKKWLRSKISSGSNLEAITTCELCKEKLHLNIENFDINELYRSHERSEYEFISCGLYLVVLLHLCEQRFSDVLGAVNDAGFFNLARTLHEHMDNLESSYAESDEDEVEDSRPSIDFCDLEDDDEEEEEEEEV", "length": 768 }, "evidence": [ { "id": "A0A8V0YG16", "url": "https://omabrowser.org/oma/group/A0A8V0YG16/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3H8K8-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF7", "gene_name": "Marchf7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESKPSRIPRRISVQPSGSLSARMVSGNRGASLNDSYHSRDSSFRLDSEYQSASASASASPFQSTWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTSTSAGRNIGSGLNTVSDSSWRHSQVPRSSSMVLGSFGTDLIRERRDLERRADSSISNLMDYNHRSGDFTTSSYVQERVPSSYSQGARPKENSMSTLQLNSSSTNHQLPSEHQTVSSSRDSSRNSFRSHFSPRQSQSFRNSSHPTFSYLSSRDETPIISNSERVGSSRRPFQESSDNDGRRSTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSENYISPRTLTSQSRSSGASSSEVNDGRASEASQGFRFLRRRWGLSSLSQNHSSEPDAENFNQESEGRSTGPWLSSSLRNRCTPLFSRRRREGRDESSRISPSDVPPRSHIFRRESNEVVHLEAQSDPLGAAANRPQASGASSSAAGGSPPDLPQGGRSTGIAGILPGSLFRFAVPPALGSNLTDNVMITVDIIPSGWNAADGKSDKTKSAPSRDPEKLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA", "length": 704 }, "evidence": [ { "id": "A0A8V0YG16", "url": "https://omabrowser.org/oma/group/A0A8V0YG16/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XI50-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF7", "gene_name": "Marchf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESKPSRIPRRISVQPSGSLSARMVSGNRGTSLNDSYHSRDSSFRLDSEYQSASASASASPYQSTWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTSTSAGRNIGSGLNTLSDSSWRPGQVPRSSSMVLGSFGTDLMRERRDLERRRDSSISSLMDYSHRSGDFTAPAYVQERVPSSYSQGARPKENAANTLQLNSSTNHQLPSEHQTVPSSRDSSRSSFRSHFSPRQSESFRNSSHPAFSYLSSRNETPTISSSERAGSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSENYISPRTLTSQSRNNGASSSEVNDGRASEASQGFRFLRRRWGLSSLSQNHSSEPDAENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRISPSDVPPRSHLFRRESNEVVHLEAQGDSLGAAASRPQASGASGNASASGSTPDLPQGGRNTGIAGILPGSLFRFAVPPALGSNLTDNVTITVDIIPSGWSSADGKSEKAKSAPSRDPEKLQKIKESLLLEDSDEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF", "length": 692 }, "evidence": [ { "id": "A0A8V0YG16", "url": "https://omabrowser.org/oma/group/A0A8V0YG16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H992-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF7", "gene_name": "MARCHF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA", "length": 704 }, "evidence": [ { "id": "A0A8V0YG16", "url": "https://omabrowser.org/oma/group/A0A8V0YG16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV66-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF7", "gene_name": "Marchf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESKPSRIPRRISVQPSGSLSTRMVSGNRGTSLNDSYHSRDSSFRLDSEYQSASASACASPCQPAWYSESEIPQGARARAQTQQRDHDSKRPKLSCTNCASTSAGRNGGSGLNTVSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLDRRRESSISNLMDYNHRSGDFTTSSYVQERVPSSYSQGARPKENAVSTLQLNSSSTNHQLPSDHQTVPSSRDSSRSSFRSHFSPRQSESFRNSSHPAFSYFSSRNETPTISNSERGSSQRPYRESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLSSENYISPRTLTSQSRNNGTSSSSDVSEGRAAEASQGFRFLRRRWGLSSLSQNHSSEPEAENFNQESEGRNSGPWLSSSLRNRCTPLFSRRRREGRDESSRMSTSDVPPRSHIFRRDSNEVVHLEAQGDSLGAAANRPQASGASSSAAAGGSTPELPQGGRNPGLTGILPGSLFRFAVPPALGSNLADNVMITVDIIPSGWNSTDGKNDKAKSAPSRDPEKLQKIKESLLLEDSDDEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQECMKKWLQAKINSGSSLEAVTTCELCKEKLQLNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTIEPSTRVRFINLARTLQAHMEDLETSEDEF", "length": 693 }, "evidence": [ { "id": "A0A8V0YG16", "url": "https://omabrowser.org/oma/group/A0A8V0YG16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "negative regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "negative regulation of proteasomal protein catabolic process", "id": "GO:1901799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901799", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:1902166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "positive regulation of protein polyubiquitination", "id": "GO:1902916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902916", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG16" } ], "pmid": "" }, { "name": "negative regulation of protein autoubiquitination", "id": 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"MKEREIGLFHYKHILDSEEPLRGKGCKGDLAWAALIAAVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1300, "header": "tr|A0A8V0YIT6-1|A0A8V0YIT6_CHICK Isoform 1 of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N9/entry", "sequence": { "sequence": "MGFGSVCKVSPSPSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPTAYTPMSGNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1292, "header": "tr|A0A8V0Y5N9-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3542213, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027817.1", "url": "https://www.ensembl.org/id/ENSGALT00010027817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015951.1", "url": "https://www.ensembl.org/id/ENSGALP00010015951.1" } ] } }, { "isoform_ac": "A0A8V0YAE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE2/entry", "sequence": { "sequence": "MGFGSVCKVSPSPSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRVMMWKFPCTPLLRSRMNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1292, "header": "tr|A0A8V0YAE2-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3542213, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027816.1", "url": "https://www.ensembl.org/id/ENSGALT00010027816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015950.1", "url": "https://www.ensembl.org/id/ENSGALP00010015950.1" } ] } }, { "isoform_ac": "A0A8V0YAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF6/entry", "sequence": { "sequence": "MCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1262, "header": "tr|A0A8V0YAF6-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3628295, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027839.1", "url": "https://www.ensembl.org/id/ENSGALT00010027839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015965.1", "url": "https://www.ensembl.org/id/ENSGALP00010015965.1" } ] } }, { "isoform_ac": "A0A8V0YBU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU2/entry", "sequence": { "sequence": "MKRSPFHRHGWSHLFSLVSLEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1169, "header": "tr|A0A8V0YBU2-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3364069, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027801.1", "url": "https://www.ensembl.org/id/ENSGALT00010027801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015938.1", "url": "https://www.ensembl.org/id/ENSGALP00010015938.1" } ] } }, { "isoform_ac": "A0A8V0YBU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU6/entry", "sequence": { "sequence": "SAYAAVNMCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPDCVLCTQLFSGPSPHLTTKSLILIARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1262, "header": "tr|A0A8V0YBU6-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3448191, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027809.1", "url": "https://www.ensembl.org/id/ENSGALT00010027809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015943.1", "url": "https://www.ensembl.org/id/ENSGALP00010015943.1" } ] } }, { "isoform_ac": "A0A8V0YBV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV2/entry", "sequence": { "sequence": "CGLLSICSVLLLCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPDCVLCTQLFSGPSPHLTTKSLILIARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1266, "header": "tr|A0A8V0YBV2-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3448237, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027814.1", "url": "https://www.ensembl.org/id/ENSGALT00010027814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015948.1", "url": "https://www.ensembl.org/id/ENSGALP00010015948.1" } ] } }, { "isoform_ac": "A0A8V0YBV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV7/entry", "sequence": { "sequence": "MGFGSVCKVSPSPSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1251, "header": "tr|A0A8V0YBV7-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3542213, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027819.1", "url": "https://www.ensembl.org/id/ENSGALT00010027819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015953.1", "url": "https://www.ensembl.org/id/ENSGALP00010015953.1" } ] } }, { "isoform_ac": "A0A8V0YBW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW2/entry", "sequence": { "sequence": "MGFGSVCKVSPSPSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVIFIVAFPEMMM", "length": 1286, "header": "tr|A0A8V0YBW2-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3542213, "end_pos": 3139602, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027827.1", "url": "https://www.ensembl.org/id/ENSGALT00010027827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015958.1", "url": "https://www.ensembl.org/id/ENSGALP00010015958.1" } ] } }, { "isoform_ac": "A0A8V0YE48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE48/entry", "sequence": { "sequence": "MPAAAGGLLWWSCCVLAAAAAGAPRAAAAQAVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCIGPRIEDCVGLMDRTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1283, "header": "tr|A0A8V0YE48-1|A0A8V0YIT6_CHICK Computationally mapped isoform of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3625049, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027838.1", "url": "https://www.ensembl.org/id/ENSGALT00010027838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015964.1", "url": "https://www.ensembl.org/id/ENSGALP00010015964.1" } ] } }, { "isoform_ac": "A0A8V0YIT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6/entry", "sequence": { "sequence": "MKEREIGLFHYKHILDSEEPLRGKGCKGDLAWAALIAAVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFEYLPLENLRIVRGTKLYEDRYALAIFLNYRKDGNFGLRELGLKNLTEILNGGVYVGQNKFLCFADTIHWQDIVRNPWASNFTLVPTNGSSGCGRCHKSCTGRCWGPTENHCQTLTKTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNHNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLVSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYHTIAAINPEKLNIFQTVREITGYLNIQSWPENMTDFRVFSNLVTIGGRALYSGLSLLILKQQGITSLQFQSLKQISAGNIYITDNSNLCYYHTVNWTSLFSTPSQKTVIHRNKKAENCTADGMVCNELCSSDGCWGPGPDQCLSCKRFIRGRTCIESCNLYDGEFREFANGSVCMECDPQCEKMEDNMITCYGPGPDHCTKCFHFKDGPNCVEKCPDGLQGANSFIFKYADEDRECHPCHPNCTQGCRGPASHDCIYYPWTRQSTLPQHARTPLIAAGVIGGLFIIVIMGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRNQFVYRDGGYAAEQGVPMPYRAPGCIIPEAPVAQGATAEIFEDTCCNGTLRKQVATLAKEDSSTQRYSADPTVFIPERVIRGELDEDGYMTPMRDKPKTDYLNPVEENPFVSRRKNGDLQAVDNPEYHNAPNGQPKAEDEYVNEPLYLNTFANTLENAEYLKNNLPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "length": 1300, "header": "tr|A0A8V0YIT6-1|A0A8V0YIT6_CHICK Isoform 1 of Receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=ERBB4 PE=3 SV=1 CANONICAL=A0A8V0YIT6-1" }, "locus": { "chromosome": "7", "start_pos": 3561100, "end_pos": 3140212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027834.1", "url": "https://www.ensembl.org/id/ENSGALT00010027834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015962.1", "url": "https://www.ensembl.org/id/ENSGALP00010015962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1227986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227986", "resource": "Reactome", "description": "Signaling by ERBB2" }, { "id": "R-GGA-1236394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236394", "resource": "Reactome", "description": "Signaling by ERBB4" }, { "id": "R-GGA-1250196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250196", "resource": "Reactome", "description": "SHC1 events in ERBB2 signaling" }, { "id": "R-GGA-1250342", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250342", "resource": "Reactome", "description": "PI3K events in ERBB4 signaling" }, { "id": "R-GGA-1250347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250347", "resource": "Reactome", "description": "SHC1 events in ERBB4 signaling" }, { "id": "R-GGA-1251985", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1251985", "resource": "Reactome", "description": "Nuclear signaling by ERBB4" }, { "id": "R-GGA-1253288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253288", "resource": "Reactome", "description": "Downregulation of ERBB4 signaling" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-1963640", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963640", "resource": "Reactome", "description": "GRB2 events in ERBB2 signaling" }, { "id": "R-GGA-1963642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963642", "resource": "Reactome", "description": "PI3K events in ERBB2 signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-6785631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6785631", "resource": "Reactome", "description": "ERBB2 Regulates Cell Motility" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" }, { "id": "R-GGA-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "neuregulin receptor activity", "id": "GO:0038131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "epidermal growth factor receptor activity", "id": "GO:0005006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "GABA receptor binding", "id": "GO:0050811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 32, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "ERBB4 signaling pathway", "id": "GO:0038130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of signaling", "id": "GO:0023056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of phosphate metabolic process", "id": "GO:0045937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045937", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of cell communication", "id": "GO:0010647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "central nervous system morphogenesis", "id": "GO:0021551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021551", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "cardiac muscle tissue regeneration", "id": "GO:0061026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046427", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell proliferation", "id": "GO:0050679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "mitochondrial fragmentation involved in apoptotic process", "id": "GO:0043653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "olfactory bulb interneuron differentiation", "id": "GO:0021889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "positive regulation of cardiac muscle cell proliferation", "id": "GO:0060045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "ERBB4-ERBB4 signaling pathway", "id": "GO:0038138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" }, { "name": "ERBB2-ERBB4 signaling pathway", "id": "GO:0038135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038135", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1010, "end_pos": 1012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1236, "end_pos": 1238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-1236398", "name": "ERBB4 binds NRGs or EGF-like ligands", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1236398", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236398" } ] }, { "id": "R-GGA-1250195", "name": "SHC1 phosphorylation by ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250195" } ] }, { "id": "R-GGA-1250220", "name": "Homodimerization of ERBB4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250220", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250220" } ] }, { "id": "R-GGA-1250315", "name": "Trans-autophosphorylation of ERBB4 homodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250315", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250315" } ] }, { "id": "R-GGA-1250346", "name": "Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZXS7-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250346", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250346" } ] }, { "id": "R-GGA-1250348", "name": "Phosphorylation of SHC1 by ERBB4 homodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250348", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250348" } ] }, { "id": "R-GGA-1250353", "name": "Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250353", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250353" } ] }, { "id": "R-GGA-1250357", "name": "SHC1 binds P-ERBB4 isoform dimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250357", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250357" } ] }, { "id": "R-GGA-1250370", "name": "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250370", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250370" } ] }, { "id": "R-GGA-1250380", "name": "Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250380", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250380" } ] }, { "id": "R-GGA-1250383", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "P08642-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1250383", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250383" } ] }, { "id": "R-GGA-1251997", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5X8-1", "A0A3Q2UE42-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1251997", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1251997" } ] }, { "id": "R-GGA-1252013", "name": "Translocation of ERBB4s80 to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZDU6-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1252013", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1252013" } ] }, { "id": "R-GGA-1253282", "name": "ERBB4 ubiquitination by WWP1/ITCH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZZH3-1", "A0A8V0YDQ1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1253282", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253282" } ] }, { "id": "R-GGA-1253300", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZZH3-1", "A0A8V0YDQ1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1253300", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253300" } ] }, { "id": "R-GGA-1253343", "name": "WWOX binds ERBB4s80", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F389-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1253343", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1253343" } ] }, { "id": "R-GGA-1254248", "name": "Translocation of ERBB4s80:YAP1 complex to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254248", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254248" } ] }, { "id": "R-GGA-1254251", "name": "ERBB4s80 binds YAP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254251", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254251" } ] }, { "id": "R-GGA-1254285", "name": "ERBB4s80:STAT5A complex translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254285", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254285" } ] }, { "id": "R-GGA-1254291", "name": "ERBB4s80 binds STAT5A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254291", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254291" } ] }, { "id": "R-GGA-1254376", "name": "Translocation of cytosolic ERBB4s80 to mitochondrial matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254376", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254376" } ] }, { "id": "R-GGA-1254386", "name": "ERBB4s80 forms a complex with estrogen receptor ESR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1254386", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1254386" } ] }, { "id": "R-GGA-1306969", "name": "GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZXS7-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1306969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1306969" } ] }, { "id": "R-GGA-1306972", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V0ZXS7-1", "P08642-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1306972", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1306972" } ] }, { "id": "R-GGA-1306979", "name": "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZXS7-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1306979", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1306979" } ] }, { "id": "R-GGA-1963563", "name": "MATK (CSK homologous kinase) binds phosphorylated ERBB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C2C8-1", "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963563", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963563" } ] }, { "id": "R-GGA-1963581", "name": "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963581", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963581" } ] }, { "id": "R-GGA-1963582", "name": "Trans-autophosphorylation of ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963582", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963582" } ] }, { "id": "R-GGA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "P09324-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1963586", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963586" } ] }, { "id": "R-GGA-1973956", "name": "NEDD4 binds ERBB4jmAcyt1s80 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVX3-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1973956", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1973956" } ] }, { "id": "R-GGA-1977296", "name": "NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZVX3-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1977296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1977296" } ] }, { "id": "R-GGA-1977958", "name": "ERBB4 forms heterodimers with ERBB3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1977958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1977958" } ] }, { "id": "R-GGA-1977959", "name": "ERBB4 forms heterodimers with EGFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-1977959", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1977959" } ] }, { "id": "R-GGA-2316434", "name": "PI3K phosphorylates PIP2 to PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q91044-1", "E1C093-1", "A0A8V0YHK2-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q90687-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YCV8-1", "A0A8V0YYZ7-1", "A0A8V0ZE65-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "F1NHX1-1", "A0A8V0YZE5-1", "A0A8V0Z0R8-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-2316434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2316434" } ] }, { "id": "R-GGA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0YWD3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q5F352-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YYZ7-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YZE5-1", "A0A8V0ZB33-1", "A0A3Q2U639-1", "A0A3Q2UKD3-1", "P08642-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672965" } ] }, { "id": "R-GGA-6785636", "name": "Phosphorylated ERBB2 heterodimers bind MEMO1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-6785636", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6785636" } ] }, { "id": "R-GGA-8863804", "name": "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNF4-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YAF3-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-8863804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8863804" } ] }, { "id": "R-GGA-9612219", "name": "ERBB4s80 binds to SRC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZDU6-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-9612219", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9612219" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UE42", "gene_name": "PSEN1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "A0A3Q2UE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { 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"L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z5X8", "gene_name": "PSEN2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5X8" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0Z8U4", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "A0M8T9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NHX1", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5F352", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + 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ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q8AXY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AXY6" } ] } ] }, { "uniprot_ac": "Q8JH64", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q8JH64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JH64" } ] } ] }, { "uniprot_ac": "Q8QHL3", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QHL3", "database": 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O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 729, "end_pos": 996, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.1", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YK23-1", "uniprot_ac": "A0A8V0YK23", "uniprot_id": "A0A8V0YK23_CHICK", "mass": { "chemical_mass": 76902.0, "monoisotopic_mass": 76902.0 }, "refseq": {}, "gene_names": [ { "name": "GFPT2", "type": "recommended", "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ] } ], "protein_names": [ { "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "type": "recommended", "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.16", "type": "synonym", "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GFPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23", "locus": { "chromosome": "13", "start_pos": 13602622, "end_pos": 13521291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015161", "url": "https://www.ensembl.org/id/ENSGALG00010015161" } ] } } ], "crossref": [ { "id": "A0A8V0YK23", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK23", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426962", "url": "https://www.ncbi.nlm.nih.gov/gene/426962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GCTAKYW", "url": "https://omabrowser.org/oma/group/GCTAKYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK23", "url": "https://www.orthodb.org/?gene=A0A8V0YK23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRG4", "url": "https://www.orthodb.org/?gene=A0A8V0YRG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGIFAYLNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEDKERFIKLVKKRGKVKALEEELYKQDGLDSKADFETHFGIAHTRWATHGVPSAINSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIPKLIKYMYDNRESEDTSFSALVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCNIENMKNMCNSRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVTDGKLSIHRLERSASDDPSRVIQTLQMELQQIMKGNFSAFMQKEIFEQPESVVNTMRGRVNFENSTVLLGGLKDHLKEIRRCRRLIIIGCGTSYHAATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMALRYCKERRALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFGLMMSEDRISLQKRRREIISGLKSLPEMIKEVLSLDEKIHDLALELYKQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFTKCQNALQQVTARQGRPIILCSKEDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 680, "header": "tr|A0A8V0YK23-1|A0A8V0YK23_CHICK Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Gallus gallus OX=9031 GN=GFPT2 PE=4 SV=1 CANONICAL=A0A8V0YK23-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23/entry", "sequence": { "sequence": "MCGIFAYLNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEDKERFIKLVKKRGKVKALEEELYKQDGLDSKADFETHFGIAHTRWATHGVPSAINSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIPKLIKYMYDNRESEDTSFSALVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCNIENMKNMCNSRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVTDGKLSIHRLERSASDDPSRVIQTLQMELQQIMKGNFSAFMQKEIFEQPESVVNTMRGRVNFENSTVLLGGLKDHLKEIRRCRRLIIIGCGTSYHAATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMALRYCKERRALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFGLMMSEDRISLQKRRREIISGLKSLPEMIKEVLSLDEKIHDLALELYKQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFTKCQNALQQVTARQGRPIILCSKEDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 680, "header": "tr|A0A8V0YK23-1|A0A8V0YK23_CHICK Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Gallus gallus OX=9031 GN=GFPT2 PE=4 SV=1 CANONICAL=A0A8V0YK23-1" }, "locus": { "chromosome": "13", "start_pos": 13542591, "end_pos": 13527207, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036534.1", "url": "https://www.ensembl.org/id/ENSGALT00010036534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021283.1", "url": "https://www.ensembl.org/id/ENSGALP00010021283.1" } ] } }, { "isoform_ac": "A0A8V0YRG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRG4/entry", "sequence": { "sequence": "MHHSAFFERQQGIFAYLNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEDKERFIKLVKKRGKVKALEEELYKQDGLDSKADFETHFGIAHTRWATHGVPSAINSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIPKLIKYMYDNRESEDTSFSALVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCNIENMKNMCNSRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVTDGKLSIHRLERSASDDPSRVIQTLQMELQQIMKGNFSAFMQKEIFEQPESVVNTMRGRVNFENSTVLLGGLKDHLKEIRRCRRLIIIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMALRYCKERRALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFGLMMSEDRISLQKRRREIISGLKSLPEMIKEVLSLDEKIHDLALELYKQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFTKCQNALQQVTARQGRPIILCSKEDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 691, "header": "tr|A0A8V0YRG4-1|A0A8V0YK23_CHICK Computationally mapped isoform of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Gallus gallus OX=9031 GN=GFPT2 PE=4 SV=1 CANONICAL=A0A8V0YK23-1" }, "locus": { "chromosome": "13", "start_pos": 13542591, "end_pos": 13523469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036536.1", "url": "https://www.ensembl.org/id/ENSGALT00010036536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021285.1", "url": "https://www.ensembl.org/id/ENSGALP00010021285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S5Q1-1", "protein_name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "gene_name": "GFPT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNTEVKERHIQLVKKRGNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQVPILYRTRNIENVKNICKTRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "A0A8V0YK23", "url": "https://omabrowser.org/oma/group/A0A8V0YK23/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O94808-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "GFPT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLENVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "A0A8V0YK23", "url": "https://omabrowser.org/oma/group/A0A8V0YK23/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4KMC4-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "Gfpt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERHIHLVKKKGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNVVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCTIENVKNICKTRLKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQTRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "A0A8V0YK23", "url": "https://omabrowser.org/oma/group/A0A8V0YK23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LIP9-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "gene_name": "GFAT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MCGIFAYLNFHANKERRYILDVLFNGLRRLEYRGYDSAGIAIDNSSPSSSPLVFRQAGNIESLVNSVNEEITNTDLNLDEVFYFHAGIAHTRWATHGEPAPRNSHPQSSGPGDDFLVVHNGVITNYEVLKETLVRHGFTFESDTDTEVIPKLAKFVFDKANEEGGQTVTFCEVVFEVMRHLEGAYALIFKSWHYPNELIACKLGSPLLLGVKELDQGESNSHVFQDAHFLSKNDHPKEFFLSSDPHALVEHTKKVLVIEDGEVVNLKDGGVSILKFENERGRCNGLSRPASVERALSVLEMEVEQISKGKYDHYMQKEIHEQPESLTTTMRGRLIRGGSRKTKTVLLGGLKDHLKTIRRSRRIVFIGCGTSYNAALASRPILEELSGIPVSMEIASDLWDRQGPIYREDTAVFVSQSGETADTLLALDYARENGALCVGITNTVGSSIARKTHCGVHINAGAEIGVASTKAYTSQIVVMVMLALAIGSDTISSQKRREAIIDGLLDLPYKVKEVLKLDDEMKDLAQLLIDEQSLLVFGRGYNYATALEGALKVKEVALMHSEGILAGEMKHGPLALVDENLPIAVIATRDACFSKQQSVIQQLHARKGRLIVMCSKGDAASVSSSGSCRAIEVPQVEDCLQPVINIVPLQLLAYHLTVLRGHNVDQPRNLAKSVTTQ", "length": 677 }, "evidence": [ { "id": "A0A8V0YK23", "url": "https://omabrowser.org/oma/group/A0A8V0YK23/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z2Z9-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "Gfpt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERHIHLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYPTCNIENVKNICKTRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSATDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "A0A8V0YK23", "url": "https://omabrowser.org/oma/group/A0A8V0YK23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine metabolic process", "id": "GO:0006047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" }, { "name": "fructose 6-phosphate metabolic process", "id": "GO:0006002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" }, { "name": "carbohydrate derivative biosynthetic process", "id": "GO:1901137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutamine-fructose-6-phosphate transaminase (isomerizing) activity", "id": "GO:0004360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-449701" ], "enzyme_list": [ "A0A8V0YK23-1", "A0A8V0Z9C7-1" ], "evidence": [ { "id": "R-GGA-449715", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449715" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449701", "participant_name": "GlcN6P [cytosol]", "crossref": [ { "id": "75989", "database": "ChEBI", "url": "" }, { "id": "ZINC000004097103", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YK23", "gene_name": "GFPT2", "activity": [ { "ec_number": "2.6.1.16", "activity": "D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.", "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ] }, { "ec_number": "2.6.1.16", "activity": "", "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" } ] } ] }, { "uniprot_ac": "A0A8V0Z9C7", "gene_name": "GFPT1", "activity": [ { "ec_number": "2.6.1.16", "activity": "D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.", "evidence": [ { "id": "A0A8V0Z9C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C7" } ] }, { "ec_number": "2.6.1.16", "activity": "", "evidence": [ { "id": "A0A8V0Z9C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" }, { "id": "PS51278", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutamine amidotransferase type-2", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 288, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YK23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK23" }, { "id": "PS51464", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51464" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SIS", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 497, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.6.1.16", "ec_name": "D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.", "evidence": [ { "id": "2.6.1.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.16" }, { "id": "2.6.1.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 }, { "start_pos": 349, "end_pos": 351 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YG36-1", "uniprot_ac": "A0A8V0YG36", "uniprot_id": "A0A8V0YG36_CHICK", "mass": { "chemical_mass": 61922.0, "monoisotopic_mass": 61922.0 }, "refseq": { "ac": "XP_015140055", "name": "wiskott-Aldrich syndrome protein family member 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140055" }, "gene_names": [ { "name": "WASF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YG36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ] }, { "name": "WASF1", "type": "synonym", "evidence": [ { "id": "XP_015140055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140055" } ] } ], "protein_names": [ { "name": "Wiskott-Aldrich syndrome protein family member", "type": "recommended", "evidence": [ { "id": "A0A8V0YG36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36/entry#names_and_taxonomy" } ] }, { "name": "WASP family protein member", "type": "synonym", "evidence": [ { "id": "A0A8V0YG36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36/entry#names_and_taxonomy" } ] }, { "name": "wiskott-Aldrich syndrome protein family member 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015140055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140055" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140055.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140055" } ] }, { "annotation": "Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. Also involved in the regulation of mitochondrial dynamics.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG31#function" }, { "database": "UniProtKB", "id": "ARBA00045579", "url": "https://www.uniprot.org/uniprotkb/ARBA00045579#function" }, { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36#function" }, { "database": "UniProtKB", "id": "A0A8V0YUA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA1#function" }, { "database": "UniProtKB", "id": "A0A8V0YUA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WASF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36", "locus": { "chromosome": "3", "start_pos": 66435829, "end_pos": 66355447, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014030", "url": "https://www.ensembl.org/id/ENSGALG00010014030" } ] } } ], "crossref": [ { "id": "A0A8V0YG36", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG36", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421761", "url": "https://www.ncbi.nlm.nih.gov/gene/421761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WGEQESN", "url": "https://omabrowser.org/oma/group/WGEQESN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG31", "url": "https://www.orthodb.org/?gene=A0A8V0YG31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG36", "url": "https://www.orthodb.org/?gene=A0A8V0YG36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUA1", "url": "https://www.orthodb.org/?gene=A0A8V0YUA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUA4", "url": "https://www.orthodb.org/?gene=A0A8V0YUA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12902:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12902:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015140055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YG31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTTQDQQLFDRKTLPIPLQETYDICEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFESRSQAYVDHMDGSYSLSALPYSQMSELLNRAEERVLVRPHEPPPPPPMHGAGDAKPVPPCVSSTTGLVENRPQSPATGRPPVFVSPTPPPPPPPPLPSALSTSSLRAAMTSTPPPPVPPPPPPPAAALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLAQPSPPVTRAAQVCEAVPVHPVPPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALSHPTPVLHPPPTTIVPGPHAPLMPPSPPSQVIPAPEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 562, "header": "tr|A0A8V0YG36-1|A0A8V0YG36_CHICK Isoform 1 of Wiskott-Aldrich syndrome protein family member OS=Gallus gallus OX=9031 GN=WASF1 PE=3 SV=1 CANONICAL=A0A8V0YG36-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG31/entry", "sequence": { "sequence": "MRAASFIRERKSLRFAGPLIHFRMPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTTQDQQLFDRKTLPIPLQETYDICEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFESRSQAYVDHMDGSYSLSALPYSQMSELLNRAEERVLVRPHEPPPPPPMHGAGDAKPVPPCVSSTTGLVENRPQSPATGRPPVFVSPTPPPPPPPPLPSALSTSSLRAAMTSTPPPPVPPPPPPPAAALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLAQPSPPVTRAAQVCEAVPVHPVPPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALSHPTPVLHPPPTTIVPGPHAPLMPPSPPSQVIPAPEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 585, "header": "tr|A0A8V0YG31-1|A0A8V0YG31_CHICK Computationally mapped isoform of Wiskott-Aldrich syndrome protein family member OS=Gallus gallus OX=9031 GN=WASF1 PE=3 SV=1 CANONICAL=A0A8V0YG36-1" }, "locus": { "chromosome": "3", "start_pos": 66435074, "end_pos": 66404230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033650.1", "url": "https://www.ensembl.org/id/ENSGALT00010033650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019812.1", "url": "https://www.ensembl.org/id/ENSGALP00010019812.1" } ] } }, { "isoform_ac": "A0A8V0YG36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36/entry", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTTQDQQLFDRKTLPIPLQETYDICEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFESRSQAYVDHMDGSYSLSALPYSQMSELLNRAEERVLVRPHEPPPPPPMHGAGDAKPVPPCVSSTTGLVENRPQSPATGRPPVFVSPTPPPPPPPPLPSALSTSSLRAAMTSTPPPPVPPPPPPPAAALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLAQPSPPVTRAAQVCEAVPVHPVPPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALSHPTPVLHPPPTTIVPGPHAPLMPPSPPSQVIPAPEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 562, "header": "tr|A0A8V0YG36-1|A0A8V0YG36_CHICK Isoform 1 of Wiskott-Aldrich syndrome protein family member OS=Gallus gallus OX=9031 GN=WASF1 PE=3 SV=1 CANONICAL=A0A8V0YG36-1" }, "locus": { "chromosome": "3", "start_pos": 66435074, "end_pos": 66407969, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033655.1", "url": "https://www.ensembl.org/id/ENSGALT00010033655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019817.1", "url": "https://www.ensembl.org/id/ENSGALP00010019817.1" } ] } }, { "isoform_ac": "A0A8V0YUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA1/entry", "sequence": { "sequence": "MEARVIWLIRASLPHYCTLQVCSILITCSKRGWKRMLLVLNEGSLQWFAGPLIHFRMPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTTQDQQLFDRKTLPIPLQETYDICEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFESRSQAYVDHMDGSYSLSALPYSQMSELLNRAEERVLVRPHEPPPPPPMHGAGDAKPVPPCVSSTTGLVENRPQSPATGRPPVFVSPTPPPPPPPPLPSALSTSSLRAAMTSTPPPPVPPPPPPPAAALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLAQPSPPVTRAAQVCEAVPVHPVPPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALSHPTPVLHPPPTTIVPGPHAPLMPPSPPSQVIPAPEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 618, "header": "tr|A0A8V0YUA1-1|A0A8V0YG36_CHICK Computationally mapped isoform of Wiskott-Aldrich syndrome protein family member OS=Gallus gallus OX=9031 GN=WASF1 PE=3 SV=1 CANONICAL=A0A8V0YG36-1" }, "locus": { "chromosome": "3", "start_pos": 66435074, "end_pos": 66357523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033651.1", "url": "https://www.ensembl.org/id/ENSGALT00010033651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019813.1", "url": "https://www.ensembl.org/id/ENSGALP00010019813.1" } ] } }, { "isoform_ac": "A0A8V0YUA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA4/entry", "sequence": { "sequence": "MGGLLFILSYAAASRFAGPLIHFRMPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTTQDQQLFDRKTLPIPLQETYDICEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFESRSQAYVDHMDGSYSLSALPYSQMSELLNRAEERVLVRPHEPPPPPPMHGAGDAKPVPPCVSSTTGLVENRPQSPATGRPPVFVSPTPPPPPPPPLPSALSTSSLRAAMTSTPPPPVPPPPPPPAAALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLAQPSPPVTRAAQVCEAVPVHPVPPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALSHPTPVLHPPPTTIVPGPHAPLMPPSPPSQVIPAPEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 586, "header": "tr|A0A8V0YUA4-1|A0A8V0YG36_CHICK Computationally mapped isoform of Wiskott-Aldrich syndrome protein family member OS=Gallus gallus OX=9031 GN=WASF1 PE=3 SV=1 CANONICAL=A0A8V0YG36-1" }, "locus": { "chromosome": "3", "start_pos": 66435074, "end_pos": 66355500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033656.1", "url": "https://www.ensembl.org/id/ENSGALT00010033656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019818.1", "url": "https://www.ensembl.org/id/ENSGALP00010019818.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 323, "start_aa": "Thr", "end_pos": 323, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr323", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-5663213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "resource": "Reactome", "description": "RHO GTPases Activate WASPs and WAVEs" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V6V5-1", "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "WASF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPTTALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 559 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GXM4-1", "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "Wasf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLLETRPQSPAAGRAPVFVSPTPPPPPPPLPSTLSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 559 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0IIJ3-1", "protein_name": "Actin-binding protein WASF1", "gene_name": "WASF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPTTALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVTPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 559 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54NF8-1", "protein_name": "Protein SCAR", "gene_name": "scrA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLITRYLPSVTDNNQPALEGQSKDQIVDTVITSTTVGIINQLTMLVAHSNSIFTALANDANLVTQRIEKLGSRIRPLIQSIPSIEDYHRNTSIDTMNSKPRAEFHADNSERNQHFTHASIPASINTVYEKCKPPPNLQLLDPYMDDGQKSLKLYTNPDFFMDEWVAEQQKLHEEARQRKRERREARLKKKGEKNEVEVKKVKSVTKVRYDPVTGEKITINIESPHTSSPQIQHQSNNTATPQHTTQHFGTNQYQAPPPPPLSQSSPSQQHSPINSYTPPPPPLNTSTPSPSSSFQGRPPSTGFNTPPPPMSNNNNMPPPPPMQQNGGAANNRLSVHNSAPIVAAPAPPPPPPPPSAPAPPPPPMAKAGGGASDIKPKASGARSDLLSSIMQGMALKPAEERKVAEAPKKEEALNVADILARRIAWAGDSDSSEDESDDSDWD", "length": 443 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJU7-1", "protein_name": "Actin-binding protein WASF1", "gene_name": "Wasf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNVLTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLSRAEERVLVRPHEPPPPPPMHAAGDARPTPTCVSSAAGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAPALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSPAPGPHAPLMPPSPPSQVLPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 559 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R5H6-1", "protein_name": "Actin-binding protein WASF1", "gene_name": "Wasf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHYETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPTPTCISSATGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVAVAALAHPPSGLHPAPSTAPGPHAPLMPPSPPSQVLPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE", "length": 559 }, "evidence": [ { "id": "A0A8V0YG36", "url": "https://omabrowser.org/oma/group/A0A8V0YG36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "modification of postsynaptic actin cytoskeleton", "id": "GO:0098885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "cellular response to brain-derived neurotrophic factor stimulus", "id": "GO:1990416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "positive regulation of neurotrophin TRK receptor signaling pathway", "id": "GO:0051388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "positive regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:2000601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "lamellipodium morphogenesis", "id": "GO:0072673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "dendrite extension", "id": "GO:0097484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "SCAR complex", "id": "GO:0031209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG36" }, { "id": "PS51082", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH2", "eco_id": "ECO_0000259", "start_pos": 500, "end_pos": 517, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 323 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJM9-1", "uniprot_ac": "A0A8V0YJM9", "uniprot_id": "A0A8V0YJM9_CHICK", "mass": { "chemical_mass": 91822.0, "monoisotopic_mass": 91822.0 }, "refseq": { "ac": "XP_003642088", "name": "PH and SEC7 domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642088" }, "gene_names": [ { "name": "PSD2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ] }, { "name": "PSD2", "type": "synonym", "evidence": [ { "id": "XP_003642088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642088" } ] } ], "protein_names": [ { "name": "PH and SEC7 domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642088" } ] }, { "name": "Pleckstrin and Sec7 domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003642088.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642088" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9", "locus": { "chromosome": "13", "start_pos": 561349, "end_pos": 621894, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011875", "url": "https://www.ensembl.org/id/ENSGALG00010011875" } ] } } ], "crossref": [ { "id": "A0A8V0YJM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030836", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030836", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427605", "url": "https://www.ncbi.nlm.nih.gov/gene/427605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427605", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427605", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKETHDK", "url": "https://omabrowser.org/oma/group/PKETHDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P0H4", "url": "https://www.orthodb.org/?gene=A0A1D5P0H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJM9", "url": "https://www.orthodb.org/?gene=A0A8V0YJM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P0H4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSESRHFPLSVAARSELHSSGSQPTVQAHSDGDEQLGQPAEPASGRASPLDDAEPSPSADEEHHGDQHLAASTGEWEQEVHATSNSEGCKELALTNGVDVELGAGGEEVRLQPPDGSVPSPGSVDSGEEGSPGPQARSQALSKVLLHGFLGSAGALSADEPEEQLGFAAGDAKLSCSEDDKEHFQFKDIRDGFSSTFEKIVESDLMKGTYYSSLDSLDVLSLTDETDSCVSFEAPLTPLIQQRVKESPELLEQKLVAQQRESPHHMVADKQEQAAAKPAEVDFGSPLRHSITSSRSENVLSRLSLKNIPNGFHVEGSEEDATKIINSISDASLKDALSDSDSDMGSTEQLDQGSTDTLANGCRADSEAAKRLAKRLYNLEGFKRCDVARQLGKNNEFSKLVAEEYLSFFDFTGLTLDKALRTFLKAFPLMGETQERERVLIHFSRRYCQCNPEESTSEDGVHTLTCALMLLNTDLHGHVNIGKKMSCQQFITNLDGLNDGKDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGASAKKVTRIVDSSNPFLDIPQALNAVTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYKPDKDLSEVDLKNAIRVHHALATKASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAICSMKKFCRPLLPSSMTKLCQEEQLRSHENKMKQIADELAEHKSHPVEKSLKSKEAEEYRLKEHYLIFEKSRYETYINLLCMKIKVGTDDLERIETSFFKVEADDIALRKTHSSPSLSQGHMSVSCKVEKDIIEQNT", "length": 828, "header": "tr|A0A8V0YJM9-1|A0A8V0YJM9_CHICK Isoform 1 of Pleckstrin and Sec7 domain containing 2 OS=Gallus gallus OX=9031 GN=PSD2 PE=4 SV=1 CANONICAL=A0A8V0YJM9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0H4/entry", "sequence": { "sequence": "MSESRHFPLSVAARSELHSSGSQPTVQAHSDGDEQLGQPAEPASGRASPLDDAEPSPSADEEHHGDQHLAASTGEWEQEVHATSNSEGCKELALTNGVDVELGAGGEEVRLQPPDGSVPSPGSVDSGEEGSPGPQARSQALSKVLLHGFLGSAGALSADEPEEQLGFAAGDAKLSCSEDDKEHFQFKDIRDGFSSTFEKIVESDLMKGTYYSSLDSLDVLSLTDETDSCVSFEAPLTPLIQQRVKESPELLEQKLVAQQRESPHHMVADKQEQAAAKPAEVDFGSPLRHSITSSRSENVLSRLSLKNIPNGFHVEGSEEDATKIINSISDASLKDALSDSDSDMGSTEQLDQGSTDTLANGCRADSEAAKRLAKRLYNLEGFKRCDVARQLGKNNEFSKLVAEEYLSFFDFTGLTLDKALRTFLKAFPLMGETQERERVLIHFSRRYCQCNPEESTSEDGVHTLTCALMLLNTDLHGHNIGKKMSCQQFITNLDGLNDGKDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGASAKKVTRIVDSSNPFLDIPQALNAVTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYKPDKDLSEVDLKNAIRVHHALATKASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAICSMKKFCRPLLPSSMTKLCQEEQLRSHENKMKQIADELAEHKSHPVEKSLKSKEAEEYRLKEHYLIFEKSRYETYINLLCMKIKVGTDDLERIETSFFKVEADDIALRKTHSSPSLSQGHMSVSCKVEKDIIEQNT", "length": 827, "header": "tr|A0A1D5P0H4-1|A0A1D5P0H4_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 2 OS=Gallus gallus OX=9031 GN=PSD2 PE=4 SV=1 CANONICAL=A0A8V0YJM9-1" }, "locus": { "chromosome": "13", "start_pos": 603664, "end_pos": 562353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028373.1", "url": "https://www.ensembl.org/id/ENSGALT00010028373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016262.1", "url": "https://www.ensembl.org/id/ENSGALP00010016262.1" } ] } }, { "isoform_ac": "A0A8V0YJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9/entry", "sequence": { "sequence": "MSESRHFPLSVAARSELHSSGSQPTVQAHSDGDEQLGQPAEPASGRASPLDDAEPSPSADEEHHGDQHLAASTGEWEQEVHATSNSEGCKELALTNGVDVELGAGGEEVRLQPPDGSVPSPGSVDSGEEGSPGPQARSQALSKVLLHGFLGSAGALSADEPEEQLGFAAGDAKLSCSEDDKEHFQFKDIRDGFSSTFEKIVESDLMKGTYYSSLDSLDVLSLTDETDSCVSFEAPLTPLIQQRVKESPELLEQKLVAQQRESPHHMVADKQEQAAAKPAEVDFGSPLRHSITSSRSENVLSRLSLKNIPNGFHVEGSEEDATKIINSISDASLKDALSDSDSDMGSTEQLDQGSTDTLANGCRADSEAAKRLAKRLYNLEGFKRCDVARQLGKNNEFSKLVAEEYLSFFDFTGLTLDKALRTFLKAFPLMGETQERERVLIHFSRRYCQCNPEESTSEDGVHTLTCALMLLNTDLHGHVNIGKKMSCQQFITNLDGLNDGKDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGASAKKVTRIVDSSNPFLDIPQALNAVTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYKPDKDLSEVDLKNAIRVHHALATKASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAICSMKKFCRPLLPSSMTKLCQEEQLRSHENKMKQIADELAEHKSHPVEKSLKSKEAEEYRLKEHYLIFEKSRYETYINLLCMKIKVGTDDLERIETSFFKVEADDIALRKTHSSPSLSQGHMSVSCKVEKDIIEQNT", "length": 828, "header": "tr|A0A8V0YJM9-1|A0A8V0YJM9_CHICK Isoform 1 of Pleckstrin and Sec7 domain containing 2 OS=Gallus gallus OX=9031 GN=PSD2 PE=4 SV=1 CANONICAL=A0A8V0YJM9-1" }, "locus": { "chromosome": "13", "start_pos": 603664, "end_pos": 562353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028363.1", "url": "https://www.ensembl.org/id/ENSGALT00010028363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016256.1", "url": "https://www.ensembl.org/id/ENSGALP00010016256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427605", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427605", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACB6-1", "protein_name": "Pleckstrin and Sec7 domain containing 2", "gene_name": "Psd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEEKLPSDLHKEEGAIQDHSLEPEEGPGVQNGTAASESLNSHVISPVSEKTGTLEGTMEPVGNPDVALPGLSLSLTNGLALGQDGNILEDSVESRPWRASGPAEEEDTPRSLCLDAEDTQLGLDCPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPEPAGLGIGDIGPEGDLGAAGGGDGELGSPLRRSISSSRSENVLSHLSLTSMPNGFHEDEPGGSGGDDEDDEDTDKVLNSASDTSLKDGLSDSDSELSSSEGLEPGSTDPMANGCQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHVNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRFCQEEQLRSHENKLRQVTAELAEHRCHPLERGLKSKEAEEYRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATLEGEDPALRKTHSSPALSLGHGPVTGSKAAKDASASDT", "length": 772 }, "evidence": [ { "id": "A0A8V0YJM9", "url": "https://omabrowser.org/oma/group/A0A8V0YJM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MZN6-1", "protein_name": "Pleckstrin and Sec7 domain containing 2", "gene_name": "PSD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEDTLLSTLPGEDGATWDPSLEPEEEPGVQNGMASSEDLNSSHTSPGHAMRGPLAGTEGHTKGLDVALHGLSLGLSLTNGLALGPDSNVLEHSTDPRPWRAGGLAEGDDASRSLCPDTEDPPLGPGGPGEPDVRDGFSATFEKIVESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPELGAGLGTGDMGSEGDMGAAGGGGVLGSPLRRSISGSRSENVLSRLSLTAVPNGFHEDGPLGPRGDEEDDEEEEEEEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLESGSTDPLANGGQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGSNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPSFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHKCHPVERGIKSKEAEENRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHGTVTGSKAMRDTTGPDT", "length": 780 }, "evidence": [ { "id": "A0A8V0YJM9", "url": "https://omabrowser.org/oma/group/A0A8V0YJM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P1I6-1", "protein_name": "PH and SEC7 domain-containing protein 2", "gene_name": "Psd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEEKLPCELHKEGSATQEDHGLEPEEEPGLQNGTAASEGLSSHISGPGGEKTLEGTMEPVRGPDVALPGLNLSLTNGLALGQDGNILEDSIEFKTWRSGPAEEEDVPGSPCPDAGDPQLGLDCPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPEAGAGLGNGDMGPEGDLGATGGCDGELGSPLRRSISSSRSENVLSHLSLTSVPNGFHEDGPGGSGGDDEDDEDTDKLLNSASDTSLKDGLSDSDSELSSSEGLEPGSTDPLANGCQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALNATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRLDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHRCHPLERGLKSKEAEEYRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATIEGDDPALRKTHSSPALSLGHGPVTGSKATKDTSASDT", "length": 770 }, "evidence": [ { "id": "A0A8V0YJM9", "url": "https://omabrowser.org/oma/group/A0A8V0YJM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQI7-1", "protein_name": "PH and SEC7 domain-containing protein 2", "gene_name": "PSD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDKLLSAVPEEGDATRDPGPEPEEEPGVRNGMASEGLNSSLCSPGHERRGTPADTEEPTKDPDVAFHGLSLGLSLTNGLALGPDLNILEDSAESRPWRAGVLAEGDNASRSLYPDAEDPQLGLDGPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDGLSLTDESDSCVSFEAPLTPLIQQRARDSPEPGAGLGIGDMAFEGDMGAAGGDGELGSPLRRSISSSRSENVLSRLSLMAMPNGFHEDGPQGPGGDEDDDEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLEPGSADPLANGCQGVSEAAHRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDGALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQLTAELAEHRCHPVERGIKSKEAEEYRLKEHYLTFEKSRYETYIHLLAMKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHVTGSKTTKDATGPDT", "length": 771 }, "evidence": [ { "id": "A0A8V0YJM9", "url": "https://omabrowser.org/oma/group/A0A8V0YJM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 568, "end_pos": 681, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM9" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 518, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIU8-1", "uniprot_ac": "A0A8V0YIU8", "uniprot_id": "A0A8V0YIU8_CHICK", "mass": { "chemical_mass": 72344.0, "monoisotopic_mass": 72344.0 }, "refseq": {}, "gene_names": [ { "name": "GTPBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] } ], "protein_names": [ { "name": "GTP-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.3", "type": "synonym", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8#function" }, { "database": "UniProtKB", "id": "ARBA00094218", "url": "https://www.uniprot.org/uniprotkb/ARBA00094218#function" }, { "database": "UniProtKB", "id": "A0A1D5P2N4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N4#function" }, { "database": "UniProtKB", "id": "A0A8V0YNM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTPBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8", "locus": { "chromosome": "1", "start_pos": 50856198, "end_pos": 50873412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012753", "url": "https://www.ensembl.org/id/ENSGALG00010012753" } ] } } ], "crossref": [ { "id": "A0A8V0YIU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030783", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030783", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03694", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03694", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03708", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03708", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418022", "url": "https://www.ncbi.nlm.nih.gov/gene/418022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418022", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418022", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P2N4", "url": "https://www.orthodb.org/?gene=A0A1D5P2N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGR6", "url": "https://www.orthodb.org/?gene=A0A8V0YGR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIU8", "url": "https://www.orthodb.org/?gene=A0A8V0YIU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNM9", "url": "https://www.orthodb.org/?gene=A0A8V0YNM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43721:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43721:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P2N4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAERSRSPAGGSPVPACMFAPEPGSPGGRPRLAAAACSLRSSFEAEDGEALNGEPEIDLTSKLVMVSPTSEQYDSLLRQMSERIDEGCGETIYVIGQGSDGTEYGLSEADMEASYATLKSMAEQIEADVILLREHQEAGGKVQDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQEETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLPIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGALTKREDGVPPVGMATGGPLVGDEPPSTAAAPPTPTALQPSSKVGGGGRRRGGQRHKVKSQGACVTPASGC", "length": 669, "header": "tr|A0A8V0YIU8-1|A0A8V0YIU8_CHICK Isoform 1 of GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=GTPBP1 PE=1 SV=1 CANONICAL=A0A8V0YIU8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N4/entry", "sequence": { "sequence": "MAAAERSRSPAGGSPVPACMFAPEPGSPGGRPRLAAAACSLRSSFEAEDGEALNGEPEIDLTSKLVMVSPTSEQYDSLLRQMSERIDEGCGETIYVIGQGSDGTEYGLSEADMEASYATLKSMAEQIEADVILLREHQEAGGKVQDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLPIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGALTKREDGVPPVGMATGGPLVGDEPPSTAAAPPTPTALQPSSKVGGGGRRRGGQRHKVKSQGACVTPASGC", "length": 668, "header": "tr|A0A1D5P2N4-1|A0A1D5P2N4_CHICK Computationally mapped isoform of GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=GTPBP1 PE=1 SV=1 CANONICAL=A0A8V0YIU8-1" }, "locus": { "chromosome": "1", "start_pos": 50873378, "end_pos": 50858353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030570.1", "url": "https://www.ensembl.org/id/ENSGALT00010030570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017736.1", "url": "https://www.ensembl.org/id/ENSGALP00010017736.1" } ] } }, { "isoform_ac": "A0A8V0YGR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR6/entry", "sequence": { "sequence": "MAAAERSRSPAGGSPVPACMFAPEPGSPGGRPRLAAAACSLRSSFEAEDGEALNGEPEIDLTSKLVMVSPTSEQYDSLLRQMSERIDEGCGETIYVIGQGSDGTEYGLMHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGALTKREDGVPPVGMATGGPLVGDEPPSTAAAPPTPTALQPSVSEGSSLSFLALCSLFSSCWRKDALEHHHYSLIALTLRLAVWQKQMEI", "length": 282, "header": "tr|A0A8V0YGR6-1|A0A8V0YIU8_CHICK Computationally mapped isoform of GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=GTPBP1 PE=1 SV=1 CANONICAL=A0A8V0YIU8-1" }, "locus": { "chromosome": "1", "start_pos": 50873378, "end_pos": 50859842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030534.1", "url": "https://www.ensembl.org/id/ENSGALT00010030534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017711.1", "url": "https://www.ensembl.org/id/ENSGALP00010017711.1" } ] } }, { "isoform_ac": "A0A8V0YIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8/entry", "sequence": { "sequence": "MAAAERSRSPAGGSPVPACMFAPEPGSPGGRPRLAAAACSLRSSFEAEDGEALNGEPEIDLTSKLVMVSPTSEQYDSLLRQMSERIDEGCGETIYVIGQGSDGTEYGLSEADMEASYATLKSMAEQIEADVILLREHQEAGGKVQDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQEETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLPIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGALTKREDGVPPVGMATGGPLVGDEPPSTAAAPPTPTALQPSSKVGGGGRRRGGQRHKVKSQGACVTPASGC", "length": 669, "header": "tr|A0A8V0YIU8-1|A0A8V0YIU8_CHICK Isoform 1 of GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=GTPBP1 PE=1 SV=1 CANONICAL=A0A8V0YIU8-1" }, "locus": { "chromosome": "1", "start_pos": 50873378, "end_pos": 50858353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030563.1", "url": "https://www.ensembl.org/id/ENSGALT00010030563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017732.1", "url": "https://www.ensembl.org/id/ENSGALP00010017732.1" } ] } }, { "isoform_ac": "A0A8V0YNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM9/entry", "sequence": { "sequence": "MAAAERSRSPAGGSPVPACMFAPEPGSPGGRPRLAAAACSLRSSFEAEDGEALNGEPEIDLTSKLVMVSPTSEQYDSLLRQMSERIDEGCGETIYVIGQGSDGTEYGLSEADMEASYATLKSMAEQIEADVILLREHQEAGGKVQDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLPIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGALTKREDGVPPVGMATGGPLVGDEPPSTAAAPPTPTALQPSPALDEEPHIREGNKSQKLEEEAGDEEVSAIK", "length": 669, "header": "tr|A0A8V0YNM9-1|A0A8V0YNM9_CHICK Computationally mapped isoform of GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=GTPBP1 PE=1 SV=1 CANONICAL=A0A8V0YIU8-1" }, "locus": { "chromosome": "1", "start_pos": 50873378, "end_pos": 50858394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030556.1", "url": "https://www.ensembl.org/id/ENSGALT00010030556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017725.1", "url": "https://www.ensembl.org/id/ENSGALP00010017725.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 664, "start_aa": "Thr", "end_pos": 664, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr664", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418022", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418022", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "alpha-aminoacyl-tRNA binding", "id": "GO:1904678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "RNA surveillance", "id": "GO:0071025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHRIVKVNRKGPGRPSQRAHDSSFPKPSPSSTASRPRGSPRSRARPPPMPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 550, "header": "tr|A0A8V0YK52-1|A0A8V0YK52_CHICK Isoform 1 of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMN7/entry", "sequence": { "sequence": "MMAQGNSCRKIVFMWSFDYGQTPPPAEPPMPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 531, "header": "tr|A0A1D5PMN7-1|A0A1D5PMN7_CHICK Computationally mapped isoform of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "locus": { "chromosome": "2", "start_pos": 129571117, "end_pos": 129544435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031242.1", "url": "https://www.ensembl.org/id/ENSGALT00010031242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018207.1", "url": "https://www.ensembl.org/id/ENSGALP00010018207.1" } ] } }, { "isoform_ac": "A0A8V0YH61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH61/entry", "sequence": { "sequence": "MPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKQSRVGSKNFSNMRLPRKPFWSVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 523, "header": "tr|A0A8V0YH61-1|A0A8V0YK52_CHICK Computationally mapped isoform of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "locus": { "chromosome": "2", "start_pos": 129570350, "end_pos": 129544435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031236.1", "url": "https://www.ensembl.org/id/ENSGALT00010031236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018203.1", "url": "https://www.ensembl.org/id/ENSGALP00010018203.1" } ] } }, { "isoform_ac": "A0A8V0YI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI47/entry", "sequence": { "sequence": "MPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRSVSQFLLRENHMQVWSQQHPAHQDNSCIPQVCFLQIKADENDPDVSTEAVHVLFTTSFSRANVKQQ", "length": 475, "header": "tr|A0A8V0YI47-1|A0A8V0YK52_CHICK Computationally mapped isoform of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "locus": { "chromosome": "2", "start_pos": 129570350, "end_pos": 129542821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031246.1", "url": "https://www.ensembl.org/id/ENSGALT00010031246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018211.1", "url": "https://www.ensembl.org/id/ENSGALP00010018211.1" } ] } }, { "isoform_ac": "A0A8V0YK52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK52/entry", "sequence": { "sequence": "MHRIVKVNRKGPGRPSQRAHDSSFPKPSPSSTASRPRGSPRSRARPPPMPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 550, "header": "tr|A0A8V0YK52-1|A0A8V0YK52_CHICK Isoform 1 of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "locus": { "chromosome": "2", "start_pos": 129574329, "end_pos": 129544435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031248.1", "url": "https://www.ensembl.org/id/ENSGALT00010031248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018212.1", "url": "https://www.ensembl.org/id/ENSGALP00010018212.1" } ] } }, { "isoform_ac": "A0A8V0YPX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX7/entry", "sequence": { "sequence": "MPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 449, "header": "tr|A0A8V0YPX7-1|A0A8V0YK52_CHICK Computationally mapped isoform of Dihydropyrimidinase OS=Gallus gallus OX=9031 GN=DPYS PE=1 SV=1 CANONICAL=A0A8V0YK52-1" }, "locus": { "chromosome": "2", "start_pos": 129570350, "end_pos": 129544435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031231.1", "url": "https://www.ensembl.org/id/ENSGALT00010031231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018200.1", "url": "https://www.ensembl.org/id/ENSGALP00010018200.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 545, "start_aa": "Thr", "end_pos": 545, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr545", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420266", "resource": "KEGG Pathway" }, { "id": "R-GGA-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S1E7-1", "protein_name": "Dihydropyrimidinase", "gene_name": "DPYS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCDYSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAARVIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDLTTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAGTSKQAHH", "length": 519 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14117-1", "protein_name": "Dihydropyrimidinase", "gene_name": "DPYS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP", "length": 519 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55DL0-1", "protein_name": "Dihydropyrimidinase", "gene_name": "pyd2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRVDQTGTILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPKEGIKVVDATDKLLLPGGIDTHTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWADEKVNCDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRCKELGAIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCTPVYIVHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIRPDPRTKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWENGVNTGKLTWCQFVRATSSEAARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHAVDFNIFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGPVFDGIEQRDKVRNELLRKVDRKPYEDDNTKNSSK", "length": 503 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63150-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKMFMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKGEVITLKPRETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IPQ2-1", "protein_name": "dihydropyrimidinase", "gene_name": "CRMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTSPKPVKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSISEELDRSGVRACIKVKNPPGGKSSGFW", "length": 594 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EQF5-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPVPVKRAPYKGEVTTLKARETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FMP3-1", "protein_name": "Dihydropyrimidinase", "gene_name": "PYD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALDAFFFIVSLFLLFPSPSASESTTQFCSAGRENGVGSCGVSSTRILIKGGTVVNAHHQELADVYVENGIIVAVQPNIKVGDEVTVLDATGKFVMPGGIDPHTHLAMEFMGTETIDDFFSGQAAALAGGTTMHIDFVIPVNGNLVAGFEAYENKSRESCMDYGFHMAITKWDEGVSRDMEMLVKEKGINSFKFFLAYKGSLMVTDDLLLEGLKRCKSLGALAMVHAENGDAVFEGQKRMIELGITGPEGHALSRPPVLEGEATARAIRLARFINTPLYVVHVMSVDAMDEIAKARKSGQKVIGEPVVSGLILDDHWLWDPDFTIASKYVMSPPIRPVGHGKALQDALSTGILQLVGTDHCTFNSTQKALGLDDFRRIPNGVNGLEERMHLIWDTMVESGQLSATDYVRITSTECARIFNIYPRKGAILAGSDADIIILNPNSSYEISSKSHHSRSDTNVYEGRRGKGKVEVTIAGGRIVWENEELKVVPRSGKYIEMPPFSYLFDGIEKSDANYLSSLRAPVKRVRTEAT", "length": 531 }, "evidence": [ { "id": "A0A8V0YK52", "url": "https://omabrowser.org/oma/group/A0A8V0YK52/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK52", "url": 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}, { "id": "A0A8V0YTD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 2357, "header": "tr|A0A8V0YKX1-1|A0A8V0YKX1_CHICK Isoform 1 of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVP8/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKDSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSESMHLDRNTLPKKGLRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKWWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2337, "header": "tr|A0A3Q2TVP8-1|A0A3Q2TVP8_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032869.1", "url": "https://www.ensembl.org/id/ENSGALT00010032869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019459.1", "url": "https://www.ensembl.org/id/ENSGALP00010019459.1" } ] } }, { "isoform_ac": "A0A3Q3AWS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AWS2/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKDSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRSMHLDRNTLPKKGLRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2200, "header": "tr|A0A3Q3AWS2-1|A0A8V0YKX1_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032905.1", "url": "https://www.ensembl.org/id/ENSGALT00010032905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019472.1", "url": "https://www.ensembl.org/id/ENSGALP00010019472.1" } ] } }, { "isoform_ac": "A0A8V0YF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF40/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKDSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSERYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2349, "header": "tr|A0A8V0YF40-1|A0A8V0YF40_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032853.1", "url": "https://www.ensembl.org/id/ENSGALT00010032853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019454.1", "url": "https://www.ensembl.org/id/ENSGALP00010019454.1" } ] } }, { "isoform_ac": "A0A8V0YF53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF53/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKADSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSESMHLDRNTLPKKGLRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2334, "header": "tr|A0A8V0YF53-1|A0A8V0YF53_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032884.1", "url": "https://www.ensembl.org/id/ENSGALT00010032884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019464.1", "url": "https://www.ensembl.org/id/ENSGALP00010019464.1" } ] } }, { "isoform_ac": "A0A8V0YKV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV9/entry", "sequence": { "sequence": "MQRSAELSVFKGKEVRRGCVRLQKQKSLTNLTLISEGEKRRHSYRENWFGNASKSSQSYHQQEAEAGSKGLLSKALSRSVHSLCQPGLTAPQAFQALPPAGSRTSKRSGDRRTDECFGIDNQERGKSDDENVSCTAHFPSRNWAEEEEEGCLREGTAHLDEDVIITMLGDLEQVLYTDILGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSERYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 1849, "header": "tr|A0A8V0YKV9-1|A0A8V0YKV9_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38909635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032820.1", "url": "https://www.ensembl.org/id/ENSGALT00010032820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019437.1", "url": "https://www.ensembl.org/id/ENSGALP00010019437.1" } ] } }, { "isoform_ac": "A0A8V0YKX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX1/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKADSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSESMHLDRNTLPKKGLRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2357, "header": "tr|A0A8V0YKX1-1|A0A8V0YKX1_CHICK Isoform 1 of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032837.1", "url": "https://www.ensembl.org/id/ENSGALT00010032837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019448.1", "url": "https://www.ensembl.org/id/ENSGALP00010019448.1" } ] } }, { "isoform_ac": "A0A8V0YL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL09/entry", "sequence": { "sequence": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGPTGTQHYSPKSLELTGAESSMLSCQLTLKSTCDFGERRALQGKTQELEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKADSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2180, "header": "tr|A0A8V0YL09-1|A0A8V0YL09_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38761129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032923.1", "url": "https://www.ensembl.org/id/ENSGALT00010032923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019478.1", "url": "https://www.ensembl.org/id/ENSGALP00010019478.1" } ] } }, { "isoform_ac": "A0A8V0YLJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ8/entry", "sequence": { "sequence": "MDLSSEMNKHGRNPVSHKLEDQKKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKADSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSESMHLDRNTLPKKGLRYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", "length": 2300, "header": "tr|A0A8V0YLJ8-1|A0A8V0YLJ8_CHICK Computationally mapped isoform of Neuron navigator 3 OS=Gallus gallus OX=9031 GN=NAV3 PE=3 SV=1 CANONICAL=A0A8V0YKX1-1" }, "locus": { "chromosome": "1", "start_pos": 39014225, "end_pos": 38624367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032936.1", "url": "https://www.ensembl.org/id/ENSGALT00010032936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019481.1", "url": "https://www.ensembl.org/id/ENSGALP00010019481.1" } ] } }, { "isoform_ac": "A0A8V0YTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTD5/entry", "sequence": { "sequence": "MDLSSEMNKHGRNPVSHKLEDQKKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQQVPSSPAEISQSKTQDMQSSLTARYATQSNHSGIATSQKKASRLPGPSRVPAAGSSTKVQGASNLNRRSQSFNSIDKNKPPQYANGNEKDSPKGPQPSAGMNGNVQHPTSTGQQQVSAIPSPSASKPWRSKSMNVKHSATSTMLSVKQPSPATSPTPSSDRLKPPPSEGVKPPSSGQKSMLEKFKLVNARTALRPPLSLSSGPSDSGREDDTFSECGEVDVLSGGVNSGGSTSSSPKVSPKLTPPKAGSKNLSNKKSLLQPKDKEEKNRDKNKVCTEKTVKEEKDQVTETSTKKSSKIASLIPKGSKTATAKKESLIPSSSGIPKPGSKVPTAKQNASSACAGSKEAEKLRTTKGNQSQSTPKSQLNEKASPSCGLAFSEVKEPNTALTPGPSTALSGTATSSGQSTGNGVVQLPQQQQYSHPNTATVAPFIYRTLSENDSTSLPPSDSCTSPTKMDLSFSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRSIPSLTSRSTPVTWRLGQASPRLQAGDAPSLGAGYPRSSASRFIHTDPSRFMYTTPLRRAAVSRLGNISQIDVSEKASSDLDMSSEVDAGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDLATSRDVIQRGVHDVTVDADSKDLDNISWDDSSSVSSGLSDTLDNLSTDDLNTTSSVSSYSNITASSRKNAHAQLKTDLEKRSVTDSETWGSTEELKKPEEDFDSNIDSSGKWKGLSSGLSEESEKGGQKAPLSQTGSWRRGMTTQVGATQSRHKAGTSALKTPGKTDDAKASEKVKTPLKGASIQRSPSDAGKSSGDEGKKPPSGIGRSTVTGSFGFKKSGMGSSTIITTSGATITSGSATLGKMPKSSAIGGKSSAGRKTSLDGSQNQDDGVLHMNSKTTLQYRSLPRPSKSSGSGIPGRGGHRSSTSSIDSNVSSKSAGAAATKLREPSKIGSGRSSPVTINQTDKEKEKVAVSDSESVSLSSSPKSSPTSASASGTPGLRQPGSKYPDIASPTFRRLFGAKASGKAASAPSTEGVKPTSAMPSPSTTLARQGSLESPSSGTGSMGSAGGQSGSSSPLFSKPSDLNADVVSLSHSLASSPASVHSFTSGALVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTSTQEVQSLLMRTGSVRSTLSERYTPSSRQTSQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSTSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDTSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIQKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHTHKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWLRSSFKQAFGKKKSTKPPSSHSDIEEQTDSSLPSSPKLPHSSGECGATSMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTGKPARPSSESSSSTSSSSSRQSLGLSLNNLNITESVTSDILLDDVTDGALHKEGHSVKILVTINKGYSRSKDQKSHTYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPAASLGLSSDCIASYCIGDVIRAHSLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHRRIILSGPSGTGKTYLANRLAEYIITKSGRKKTEDAIATFNVDHKSSKDLRQYLANLAEQCSADNNGADLPVVIILDNLHHISSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIETEIEKNIRNNELIKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVDGSRVWFTDLWNYSLVPYLLEAVREGLQMYGKRAPWEDPSKWVADTYPWSSASLQHEWPSLLQLRPEDVGYEGYASAKEGTTSKHVPQTDTEGDPLMNMLMRLQEAANFSSAQSCDSDSTSHHDDILDSSLESTL", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLCWRQSRTLLSLLEDTSRLVGRMKLLAFCGFLFVFLLCLSAFAAEGRNVKKGCCLKLTKMNRKVHKVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 913, "header": "tr|A0A8V0YFL4-1|A0A8V0YFL4_CHICK Isoform 1 of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y2F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2F1/entry", "sequence": { "sequence": "MNNTCVQKRETEAVSCHHHWSFRSVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 869, "header": "tr|A0A8V0Y2F1-1|A0A8V0YFL4_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3786870, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026162.1", "url": "https://www.ensembl.org/id/ENSGALT00010026162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014786.1", "url": "https://www.ensembl.org/id/ENSGALP00010014786.1" } ] } }, { "isoform_ac": "A0A8V0Y750-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y750/entry", "sequence": { "sequence": "MKQWELLLHPRNSPNLLRDHPLPMTAICVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 873, "header": "tr|A0A8V0Y750-1|A0A8V0YFL4_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3781055, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026156.1", "url": "https://www.ensembl.org/id/ENSGALT00010026156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014780.1", "url": "https://www.ensembl.org/id/ENSGALP00010014780.1" } ] } }, { "isoform_ac": "A0A8V0Y759-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y759/entry", "sequence": { "sequence": "MNNTCVQKRETEAVSCHHHWSFRSGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 837, "header": "tr|A0A8V0Y759-1|A0A8V0YFL4_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3786870, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026166.1", "url": "https://www.ensembl.org/id/ENSGALT00010026166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014790.1", "url": "https://www.ensembl.org/id/ENSGALP00010014790.1" } ] } }, { "isoform_ac": "A0A8V0Y8N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8N6/entry", "sequence": { "sequence": "MKMPSGCCQGGIGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 825, "header": "tr|A0A8V0Y8N6-1|A0A8V0YFL4_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3777363, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026145.1", "url": "https://www.ensembl.org/id/ENSGALT00010026145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014768.1", "url": "https://www.ensembl.org/id/ENSGALP00010014768.1" } ] } }, { "isoform_ac": "A0A8V0Y8P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P1/entry", "sequence": { "sequence": "MILHISSDGNRLWRVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 859, "header": "tr|A0A8V0Y8P1-1|A0A8V0YFL4_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3778657, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026150.1", "url": "https://www.ensembl.org/id/ENSGALT00010026150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014773.1", "url": "https://www.ensembl.org/id/ENSGALP00010014773.1" } ] } }, { "isoform_ac": "A0A8V0YFI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI7/entry", "sequence": { "sequence": "MKHVRHFIPSLFLSLVHVCLVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 865, "header": "tr|A0A8V0YFI7-1|A0A8V0YFI7_CHICK Computationally mapped isoform of Photoreceptor cadherin OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3775237, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026137.1", "url": "https://www.ensembl.org/id/ENSGALT00010026137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014761.1", "url": "https://www.ensembl.org/id/ENSGALP00010014761.1" } ] } }, { "isoform_ac": "A0A8V0YFK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK1/entry", "sequence": { "sequence": "MILHISSDGNRLWRGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 827, "header": "tr|A0A8V0YFK1-1|A0A8V0YFK1_CHICK Computationally mapped isoform of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3778657, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026153.1", "url": "https://www.ensembl.org/id/ENSGALT00010026153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014777.1", "url": "https://www.ensembl.org/id/ENSGALP00010014777.1" } ] } }, { "isoform_ac": "A0A8V0YFL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4/entry", "sequence": { "sequence": "MKLCWRQSRTLLSLLEDTSRLVGRMKLLAFCGFLFVFLLCLSAFAAEGRNVKKGCCLKLTKMNRKVHKVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNSAAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI", "length": 913, "header": "tr|A0A8V0YFL4-1|A0A8V0YFL4_CHICK Isoform 1 of Cadherin-related family member 1 OS=Gallus gallus OX=9031 GN=CDHR1 PE=4 SV=1 CANONICAL=A0A8V0YFL4-1" }, "locus": { "chromosome": "6", "start_pos": 3792053, "end_pos": 3742194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026168.1", "url": "https://www.ensembl.org/id/ENSGALT00010026168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014792.1", "url": "https://www.ensembl.org/id/ENSGALP00010014792.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M326-1", "protein_name": "Cadherin-related family member 1", "gene_name": "Cdhr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRHGPRAALVLGLLHIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREKEDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYVVLVPENTPAGSSIFKVHAEDKDTGSGGSVTYFLQNLHSSKFTMDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATATVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRFLNESDGVFEINETSGAISVLHSPAQLRREVYELHVQVTEVNSPGSPGAQAIVPVTIRIVDLNNHPPTFYGESGPQNKFELSIYEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVQYSIYGTGSELFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSIQEKTMVLGTPVKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIWLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITDTETLSRGSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKILPVKRVLRRRPSPAPRTVRIEWLKFKRAKAASKFILKEDPPNENCNNSRAGVTVPPRAPALPPPPKIAQRTVPTVSGSLTPQPPQPLPKPKPLGGAIQSSLVSELKQKFEKKSLDNKAYF", "length": 854 }, "evidence": [ { "id": "A0A8V0YFL4", "url": "https://omabrowser.org/oma/group/A0A8V0YFL4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8VHP6-1", "protein_name": "Cadherin-related family member 1", "gene_name": "Cdhr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRGPRVALVLGLLRIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRGSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAATKFILKEDSPNENCNNSRVGVMVPPRAPALPPPPKMASSMVAQQTVPTVSGSLTPQPSPQLPTPKTLGGPVQSSLVSELKQKFEKKSLDNKAYI", "length": 859 }, "evidence": [ { "id": "A0A8V0YFL4", "url": "https://omabrowser.org/oma/group/A0A8V0YFL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91XU7-1", "protein_name": "Cadherin-related family member 1", "gene_name": "Cdhr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRGPQVALVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVIVVTDANDEAPRFLQEPYNILVPENTPAGSSIFKVQAEDKDTGSGGSVTYFLQSLHSSKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGLFEINETSGAISVLQSPAQLRREVYELHVQVTEVNSSGSPAAQSTVPVIIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKSLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVPGGSNVVAVTAVDPDTGPWGKVQYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGEYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRSSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAASKFILKEDPPNENCNNSRVGVTVPPRAPALPPPPKMASSTVAQQTVPTVSGSLTPQPSQQLPTPKPLGGPAQSSLVSELKQKFEKKSLGNKAYV", "length": 859 }, "evidence": [ { "id": "A0A8V0YFL4", "url": "https://omabrowser.org/oma/group/A0A8V0YFL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96JP9-1", "protein_name": "Cadherin-related family member 1", "gene_name": "CDHR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRCRWAALALGLLRLCLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSLVNGNDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLVGPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYSTYGTGADLFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDMEGKYSVAEVFITLLDVNDHPPQFGKSVQKKTMVLGTPVKIEAIDEDAEEPNNLVDYSITHAEPANVFDINSHTGEIWLKNSIRSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKIDITDAETLSRSPMAAFLIQTKDNPMKAVGVLAGTMATVVAITVLISTATFWRNKKSNKVLPMRRVLRKRPSPAPRTIRIEWLKSKSTKAATKFMLKEKPPNENCNNNSPESSLLPRAPALPPPPSVAPSTGAAQWTVPTVSGSLTPQPTQPPPKPKTMGSPVQSTLISELKQKFEKKSVHNKAYF", "length": 859 }, "evidence": [ { "id": "A0A8V0YFL4", "url": "https://omabrowser.org/oma/group/A0A8V0YFL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "photoreceptor outer segment membrane", "id": "GO:0042622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL4" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 185, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 694, "end_pos": 696 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGI0-1", "uniprot_ac": "A0A8V0YGI0", "uniprot_id": "A0A8V0YGI0_CHICK", "mass": { "chemical_mass": 217082.0, "monoisotopic_mass": 217082.0 }, "refseq": { "ac": "XP_004935945", "name": "kinesin-like protein KIF13B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935945" }, "gene_names": [ { "name": "KIF13B", "type": "recommended", "evidence": [ { "id": "A0A8V0YGI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ] }, { "name": "KIF13B", "type": "synonym", "evidence": [ { "id": "XP_004935945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935945" } ] } ], "protein_names": [ { "name": "Kinesin family member 13B", "type": "synonym", "evidence": [ { "id": "A0A8V0YGI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIF13B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935945" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935945.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935945" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIF13B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0", "locus": { "chromosome": "3", "start_pos": 106027218, "end_pos": 106146655, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011061", "url": "https://www.ensembl.org/id/ENSGALG00010011061" } ] } } ], "crossref": [ { "id": "cd01365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422026", "url": "https://www.ncbi.nlm.nih.gov/gene/422026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LVCSIKI", "url": "https://omabrowser.org/oma/group/LVCSIKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3B3", "url": "https://www.orthodb.org/?gene=A0A8V0Y3B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7Z3", "url": "https://www.orthodb.org/?gene=A0A8V0Y7Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y805", "url": "https://www.orthodb.org/?gene=A0A8V0Y805", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9I7", "url": "https://www.orthodb.org/?gene=A0A8V0Y9I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH6", "url": "https://www.orthodb.org/?gene=A0A8V0YGH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGI0", "url": "https://www.orthodb.org/?gene=A0A8V0YGI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004935945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935945", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y805", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y805-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y805-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDSKVKVAVRVRPMNRRELDLHTKCVVDVDANKVILHPVNTNLSKGDASRTQPKVFAYDHCFWSMDESVKEKYAGQDVVFKCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERAQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHSVYGPYVDGLSKLAVASYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKIILTHTLYDVQSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQAAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKNIVNHAVVNEDPNARIIRELREEVEKLREQLTKAEAMKSPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDNKCFLVNLNADPALNELLVYYLKEHTLIGSDNSQDIQLCGMGILPEHCIIDITPEGQVMLTPQKNTRTFVNGSAVAGPIQLHHGDRILWGNNHFFRLNLPKKKKKLDHEDEERDNSMKCSNSVEQLDVDGDNSSEVSSEINFSYEYAQMEVTMKALGSNDPMQSILQSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQHFRSMDRFSFHSPSAQQRLRQWAEEREEMLTHSLRKLREQIVKANLYVREANFIGEELDKRTEYKVTLQIPASSLNANSKRGAILSEPAIQVRRKGKGKQIWSLEKLENRLVDMRDLYQEWKDCEEDNPVMRAYFRRADPFYDEQENHSLIGVANVFLECLFYDVKLQYAVPIINQKGEVSGRLHVEVVRVSGEIDDRLVGGEDSPDYFNENDTQERKLVCRIKILQATGLPQHLSNFVFCKYTFWDHLEPVNVAPEVDPSLSPISKEPRCMVVFDHCNEFSVNISEDFMEHLYDGALAIEVYGHKQSGDRKNPTLWDLGIIQAKTRSLRDRWSEVTRKVELWVQILELNENGEYCPVEVTPAKDVCTGGIFQLRQGQSRRIQVEVRSVQESGTLPLMEESILSVGIGCVQIKHVKSQKVPEIYQEEEDEMDSYQDRDLERLRRKWLCALTKRQEYLDQQLQKLVGKPDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDSEAGGWDATLVAEEEEEFFELQIVKHHDSEVKVEASWDSTVHDCIQLSKGTAADERVYLIVRATVQLSHPAEMHLVLRKRICVNVYGRQGFAQSFLRRMSHRSSIPGCGVTFEIVSNIPEDAQGAEEREALARMAANVEDAASADSEAYIEKYLRSVLAVENILTLDRLRQEVAVKEQLMGKGKLYRRSLSSPNVNRLSASRQDLAPPYNLSSNRSPKVPAEGRWESQQDVSQGVTNSNRGISPTRSSLPGSGQQNHSPDAGLGSLAASYLNPVKSFVPQMPKLLKSLFPVRDEKKGRQTSPLAQQAVPRIMVQSASIDASAAKIKQLNQEAAGKRPFEAAVRMTEVEKSPEKMPKVPLQQPTGDAQAQDSQEGPPSPLSEASSGYFSHSVSTATLSEALAAGSDAVVQPGGQTPALSDFPAPAVAQGFSDTPGHSNSPSESCLNNKGESLPTSSLPSAHTRSKDSTEVNGSDALKSKSSASPVTHSEQANDASVATDAKTILSTSALRMESSKQSMESAGQAAGRKETTSGASELGAPKPQVQPNQLSQPSVAASPFKIQKVKTSELKSFTSMLGTDPSCSLNTEEEQQEGEKSASAAHGLSQNGSEMAEEKLEVVSDSEDANEIPEWLKEGEYVTVGANKTGIVRYVGPTDFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVKPGRVKKAVGPARRRSTGVRLQGGASGENRRSGNFSGSASSLTSLTALAAKSEGGPTVRLEKSQKNAENRKSWAS", "length": 1957, "header": "tr|A0A8V0YGI0-1|A0A8V0YGI0_CHICK Isoform 1 of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B3/entry", "sequence": { "sequence": "MCLCLSELDLHTKCVVDVDANKVILHPVNTNLSKGDASRTQPKVFAYDHCFWSMDESVKEKYAGQDVVFKCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERAQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHSVYGPYVDGLSKLAVASYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKIILTHTLYDVQSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQAAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKNIVNHAVVNEDPNARIIRELREEVEKLREQLTKAEAMKSPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDNKCFLVNLNADPALNELLVYYLKEHTLIGSDNSQDIQLCGMGILPEHCIIDITPEGQVMLTPQKNTRTFVNGSAVAGPIQLHHGDRILWGNNHFFRLNLPKKKKKLDHEDEERDNSMKCSNSVEQLDVDGDNSSEVSSEINFSYEYAQMEVTMKALGSNDPMQSILQSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQHFRSMDRFSFHSPSAQQRLRQWAEEREEMLTHSLRKLREQIVKANLYVREANFIGEELDKRTEYKVTLQIPASSLNANSKRGAILSEPAIQVRRKGKGKQIWSLEKLENRLVDMRDLYQEWKDCEEDNPVMRAYFRRADPFYDEQENHSLIGVANVFLECLFYDVKLQYAVPIINQKGEVSGRLHVEVVRVSGEIDDRLVGGEDSPDYFNENDTQERKLVCRIKILQATGLPQHLSNFVFCKYTFWDHLEPVNVAPEVDPSLSPISKEPRCMVVFDHCNEFSVNISEDFMEHLYDGALAIEVYGHKQSGDRKNPTLWDLGIIQAKTRSLRDRWSEVTRKVELWVQILELNENGEYCPVEVTPAKDVCTGGIFQLRQGQSRRIQVEVRSVQESGTLPLMEESILSVGIGCVQIKHVKSQKVPEIYQEEEDEMDSYQDRDLERLRRKWLCALTKRQEYLDQQLQKLVGKPDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDSEAGGWDATLVAEEEEEFFELQIVKHHDSEVKVEASWDSTVHDCIQLSKGTAADERVYLIVRATVQLSHPAEMHLVLRKRICVNVYGRQGFAQSFLRRMSHRSSIPGCGVTFEIVSNIPEDAQGAEEREALARMAANVEDAASADSEAYIEKYLRSVLAVENILTLDRLRQEVAVKEQLMGKGKLYRRSLSSPNVNRLSASRQDLAPPYNLSSNRGRWESQQDVSQGVTNSNRGISPTRSSLPGSGQQNHSPDAGLGSLAASYLNPVKSFVPQMPKLLKSLFPVRDEKKGRQTSPLAQQAVPRIMVQSASIDASAAKIKQLNQEAAGKRPFEAAVRMTEVEKSPEKMPKVPLQQPTGDAQAQDSQEGPPSPLSEASSGYFSHSVSTATLSEALAAGSDAVVQPGGQTPALSDFPAPAVAQGFSDTPGHSNSPSESCLNNKGESLPTSSLPSAHTRSKDSTEVNGSDALKSKSSASPVTHSEQANDASVATDAKTILSTSALRMESSKQSMESAGQAAGRKETTSGASELGAPKPQVQPNQLSQPSVAASPFKIQKVKTSELKSFTSMLGTDPSCSLNTEEEQQEGEKSASAAHGLSQNGSEMAEEKLEVVSDSEDANEIPEWLKEGEYVTVGANKTGIVRYVGPTDFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVKPGRVKKAVGPARRRSTGVRLQGGASGENRRSGNFSGSASSLTSLTALAAKSEGGPTVRLEKSQKNAENRKSWAS", "length": 1938, "header": "tr|A0A8V0Y3B3-1|A0A8V0YGI0_CHICK Computationally mapped isoform of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106146347, "end_pos": 106028222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026510.1", "url": "https://www.ensembl.org/id/ENSGALT00010026510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015095.1", "url": "https://www.ensembl.org/id/ENSGALP00010015095.1" } ] } }, { "isoform_ac": "A0A8V0Y7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Z3/entry", "sequence": { "sequence": "MGDSKVKVAVRVRPMNRRELDLHTKCVVDVDANKVILHPVNTNLSKGDASIELIPGTVWHWTVISAKKVNLRIFTLLQPRINVHLWPEYC", "length": 90, "header": "tr|A0A8V0Y7Z3-1|A0A8V0YGI0_CHICK Computationally mapped isoform of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106146557, "end_pos": 106114168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026486.1", "url": "https://www.ensembl.org/id/ENSGALT00010026486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015079.1", "url": "https://www.ensembl.org/id/ENSGALP00010015079.1" } ] } }, { "isoform_ac": "A0A8V0Y805-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y805/entry", "sequence": { "sequence": "MCGGCGCKQGYSSSCKHQPFKRRCQVFAYDHCFWSMDESVKEKYAGQDVVFKCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERAQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHSVYGPYVDGLSKLAVASYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKIILTHTLYDVQSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQAAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKNIVNHAVVNEDPNARIIRELREEVEKLREQLTKAEAMKSPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDNKCFLVNLNADPALNELLVYYLKEHTLIGSDNSQDIQLCGMGILPEHCIIDITPEGQVMLTPQKNTRTFVNGSAVAGPIQLHHGDRILWGNNHFFRLNLPKKKKKLDHEDEERDNSMKCSNSVEQLDVDGDNSSEVSSEINFSYEYAQMEVTMKALGSNDPMQSILQSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQHFRSMDRFSFHSPSAQQRLRQWAEEREEMLTHSLRKLREQIVKANLYVREANFIGEELDKRTEYKVTLQIPASSLNANSKRGAILSEPAIQVRRKGKGKQIWSLEKLENRLVDMRDLYQEWKDCEEDNPVMRAYFRRADPFYDEQENHSLIGVANVFLECLFYDVKLQYAVPIINQKGEVSGRLHVEVVRVSGEIDDRLVGGEDSPDYFNENDTQERKLVCRIKILQATGLPQHLSNFVFCKYTFWDHLEPVNVAPEVDPSLSPISKEPRCMVVFDHCNEFSVNISEDFMEHLYDGALAIEVYGHKQSGDRKNPTLWDLGIIQAKTRSLRDRWSEVTRKVELWVQILELNENGEYCPVEVTPAKDVCTGGIFQLRQGQSRRIQVEVRSVQESGTLPLMEESILSVGIGCVQIKHVKSQKVPEIYQEEEDEMDSYQDRDLERLRRKWLCALTKRQEYLDQQLQKLVGKPDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDSEAGGWDATLVAEEEEEFFELQIVKHHDSEVKVEASWDSTVHDCIQLSKGTAADERVYLIVRATVQLSHPAEMHLVLRKRICVNVYGRQGFAQSFLRRMSHRSSIPGCGVTFEIVSNIPEDAQGAEEREALARMAANVEDAASADSEAYIEKYLRSVLAVENILTLDRLRQEVAVKEQLMGKGKLYRRSLSSPNVNRLSASRQDLAPPYNLSSNRGRWESQQDVSQGVTNSNRGISPTRSSLPGSGQQNHSPDAGLGSLAASYLNPVKSFVPQMPKLLKSLFPVRDEKKGRQTSPLAQQAVPRIMVQSASIDASAAKIKQLNQEAAGKRPFEAAVRMTEVEKSPEKMPKVPLQQPTGDAQAQDSQEGPPSPLSEASSGYFSHSVSTATLSEALAAGSDAVVQPGGQTPALSDFPAPAVAQGFSDTPGHSNSPSESCLNNKGESLPTSSLPSAHTRSKDSTEVNGSDALKSKSSASPVTHSEQANDASVATDAKTILSTSALRMESSKQSMESAGQAAGRKETTSGASELGAPKPQVQPNQLSQPSVAASPFKIQKVKTSELKSFTSMLGTDPSCSLNTEEEQQEGEKSASAAHGLSQNGSEMAEEKLEVVSDSEDANEIPEWLKEGEYVTVGANKTGIVRYVGPTDFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVKPGRVKKAVGPARRRSTGVRLQGGASGENRRSGNFSGSASSLTSLTALAAKSEGGPTVRLEKSQKNAENRKSWAS", "length": 1920, "header": "tr|A0A8V0Y805-1|A0A8V0YGI0_CHICK Computationally mapped isoform of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106134576, "end_pos": 106028222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026500.1", "url": "https://www.ensembl.org/id/ENSGALT00010026500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015089.1", "url": "https://www.ensembl.org/id/ENSGALP00010015089.1" } ] } }, { "isoform_ac": "A0A8V0Y9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9I7/entry", "sequence": { "sequence": "MGDSKVKVAVRVRPMNRRELDLHTKCVVDVDANKVILHPVNTNLSKGDASCDCIDSHSDKL", "length": 61, "header": "tr|A0A8V0Y9I7-1|A0A8V0YGI0_CHICK Computationally mapped isoform of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106146557, "end_pos": 106121116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026484.1", "url": "https://www.ensembl.org/id/ENSGALT00010026484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015077.1", "url": "https://www.ensembl.org/id/ENSGALP00010015077.1" } ] } }, { "isoform_ac": "A0A8V0YGH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH6/entry", "sequence": { "sequence": "MCGGCGCKQGYSSSCKHQPFKRRCQQDPAKDVVFKCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERAQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHSVYGPYVDGLSKLAVASYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKIILTHTLYDVQSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQAAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKNIVNHAVVNEDPNARIIRELREEVEKLREQLTKAEAMKSPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDNKCFLVNLNADPALNELLVYYLKEHTLIGSDNSQDIQLCGMGILPEHCIIDITPEGQVMLTPQKNTRTFVNGSAVAGPIQLHHGDRILWGNNHFFRLNLPKKKKKLDHEDEERDNSMKCSNSVEQLDVDGDNSSEVSSEINFSYEYAQMEVTMKALGSNDPMQSILQSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQHFRSMDRFSFHSPSAQQRLRQWAEEREEMLTHSLRKLREQIVKANLYVREANFIGEELDKRTEYKVTLQIPASSLNANSKRGAILSEPAIQVRRKGKGKQIWSLEKLENRLVDMRDLYQEWKDCEEDNPVMRAYFRRADPFYDEQENHSLIGVANVFLECLFYDVKLQYAVPIINQKGEVSGRLHVEVVRVSGEIDDRLVGGEDSPDYFNENDTQERKLVCRIKILQATGLPQHLSNFVFCKYTFWDHLEPVNVAPEVDPSLSPISKEPRCMVVFDHCNEFSVNISEDFMEHLYDGALAIEVYGHKQSGDRKNPTLWDLGIIQAKTRSLRDRWSEVTRKVELWVQILELNENGEYCPVEVTPAKDVCTGGIFQLRQGQSRRIQVEVRSVQESGTLPLMEESILSVGIGCVQIKHVKSQKVPEIYQEEEDEMDSYQDRDLERLRRKWLCALTKRQEYLDQQLQKLVGKPDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDSEAGGWDATLVAEEEEEFFELQIVKHHDSEVKVEASWDSTVHDCIQLSKGTAADERVYLIVRATVQLSHPAEMHLVLRKRICVNVYGRQGFAQSFLRRMSHRSSIPGCGVTFEIVSNIPEDAQGAEEREALARMAANVEDAASADSEAYIEKYLRSVLAVENILTLDRLRQEVAVKEQLMGKGKLYRRSLSSPNVNRLSASRQDLAPPYNLSSNRGRWESQQDVSQGVTNSNRGISPTRSSLPGSGQQNHSPDAGLGSLAASYLNPVKSFVPQMPKLLKSLFPVRDEKKGRQTSPLAQQAVPRIMVQSASIDASAAKIKQLNQEAAGKRPFEAAVRMTEVEKSPEKMPKVPLQQPTGDAQAQDSQEGPPSPLSEASSGYFSHSVSTATLSEALAAGSDAVVQPGGQTPALSDFPAPAVAQGFSDTPGHSNSPSESCLNNKGESLPTSSLPSAHTRSKDSTEVNGSDALKSKSSASPVTHSEQANDASVATDAKTILSTSALRMESSKQSMESAGQAAGRKETTSGASELGAPKPQVQPNQLSQPSVAASPFKIQKVKTSELKSFTSMLGTDPSCSLNTEEEQQEGEKSASAAHGLSQNGSEMAEEKLEVVSDSEDANEIPEWLKEGEYVTVGANKTGIVRYVGPTDFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVKPGRVKKAVGPARRRSTGVRLQGGASGENRRSGNFSGSASSLTSLTALAAKSEGGPTVRLEKSQKNAENRKSWAS", "length": 1903, "header": "tr|A0A8V0YGH6-1|A0A8V0YGH6_CHICK Computationally mapped isoform of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106134576, "end_pos": 106028222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026518.1", "url": "https://www.ensembl.org/id/ENSGALT00010026518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015101.1", "url": "https://www.ensembl.org/id/ENSGALP00010015101.1" } ] } }, { "isoform_ac": "A0A8V0YGI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0/entry", "sequence": { "sequence": "MGDSKVKVAVRVRPMNRRELDLHTKCVVDVDANKVILHPVNTNLSKGDASRTQPKVFAYDHCFWSMDESVKEKYAGQDVVFKCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERAQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHSVYGPYVDGLSKLAVASYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKIILTHTLYDVQSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQAAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKNIVNHAVVNEDPNARIIRELREEVEKLREQLTKAEAMKSPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDNKCFLVNLNADPALNELLVYYLKEHTLIGSDNSQDIQLCGMGILPEHCIIDITPEGQVMLTPQKNTRTFVNGSAVAGPIQLHHGDRILWGNNHFFRLNLPKKKKKLDHEDEERDNSMKCSNSVEQLDVDGDNSSEVSSEINFSYEYAQMEVTMKALGSNDPMQSILQSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQHFRSMDRFSFHSPSAQQRLRQWAEEREEMLTHSLRKLREQIVKANLYVREANFIGEELDKRTEYKVTLQIPASSLNANSKRGAILSEPAIQVRRKGKGKQIWSLEKLENRLVDMRDLYQEWKDCEEDNPVMRAYFRRADPFYDEQENHSLIGVANVFLECLFYDVKLQYAVPIINQKGEVSGRLHVEVVRVSGEIDDRLVGGEDSPDYFNENDTQERKLVCRIKILQATGLPQHLSNFVFCKYTFWDHLEPVNVAPEVDPSLSPISKEPRCMVVFDHCNEFSVNISEDFMEHLYDGALAIEVYGHKQSGDRKNPTLWDLGIIQAKTRSLRDRWSEVTRKVELWVQILELNENGEYCPVEVTPAKDVCTGGIFQLRQGQSRRIQVEVRSVQESGTLPLMEESILSVGIGCVQIKHVKSQKVPEIYQEEEDEMDSYQDRDLERLRRKWLCALTKRQEYLDQQLQKLVGKPDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDSEAGGWDATLVAEEEEEFFELQIVKHHDSEVKVEASWDSTVHDCIQLSKGTAADERVYLIVRATVQLSHPAEMHLVLRKRICVNVYGRQGFAQSFLRRMSHRSSIPGCGVTFEIVSNIPEDAQGAEEREALARMAANVEDAASADSEAYIEKYLRSVLAVENILTLDRLRQEVAVKEQLMGKGKLYRRSLSSPNVNRLSASRQDLAPPYNLSSNRSPKVPAEGRWESQQDVSQGVTNSNRGISPTRSSLPGSGQQNHSPDAGLGSLAASYLNPVKSFVPQMPKLLKSLFPVRDEKKGRQTSPLAQQAVPRIMVQSASIDASAAKIKQLNQEAAGKRPFEAAVRMTEVEKSPEKMPKVPLQQPTGDAQAQDSQEGPPSPLSEASSGYFSHSVSTATLSEALAAGSDAVVQPGGQTPALSDFPAPAVAQGFSDTPGHSNSPSESCLNNKGESLPTSSLPSAHTRSKDSTEVNGSDALKSKSSASPVTHSEQANDASVATDAKTILSTSALRMESSKQSMESAGQAAGRKETTSGASELGAPKPQVQPNQLSQPSVAASPFKIQKVKTSELKSFTSMLGTDPSCSLNTEEEQQEGEKSASAAHGLSQNGSEMAEEKLEVVSDSEDANEIPEWLKEGEYVTVGANKTGIVRYVGPTDFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVKPGRVKKAVGPARRRSTGVRLQGGASGENRRSGNFSGSASSLTSLTALAAKSEGGPTVRLEKSQKNAENRKSWAS", "length": 1957, "header": "tr|A0A8V0YGI0-1|A0A8V0YGI0_CHICK Isoform 1 of Kinesin family member 13B OS=Gallus gallus OX=9031 GN=KIF13B PE=1 SV=1 CANONICAL=A0A8V0YGI0-1" }, "locus": { "chromosome": "3", "start_pos": 106146557, "end_pos": 106028222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026525.1", "url": "https://www.ensembl.org/id/ENSGALT00010026525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015106.1", "url": "https://www.ensembl.org/id/ENSGALP00010015106.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1011, "start_aa": "Thr", "end_pos": 1011, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1011", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1843, "start_aa": "Thr", "end_pos": 1843, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1843", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286YCV9-1", "protein_name": "Kinesin family member 13B", "gene_name": "Kif13b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDSKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPVNTNLSKGDARGQPKIFAYDHCFWSMDESVREKYAGQEDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQTSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHGIIDITPEGQVVLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDREASLKNDSSSEQLDADGDSSSEVSSEINFNFEYAQMEVTMKALGSNDPMQSILSSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPERQNCRGVDRLSFHSPSAQQRLKQWAEEREATLNNSLMRLREQIVKANLLVREASYIAEELDKRTEYKVTLQIPTSSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLENRLLDMRDLYQEWKECEEDSPVSRSYFKRADPFYDEQENHSLIGVANVFLETLFYDVKLQYAVPIINQKGEVAGRLHVEVMRLSGAIGERIAGGDDPTEVSSEKEAQENRLVCMVKILQATGLPQHLCHFVFCKYDFWDQQEPVTVAPEVDTSSSPTSKQPQCMVVFDHCSEFSVNITEDFIEYLSEGALAIEVYGHKMNDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGDYCPVEVIAAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRSPKIHENVHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKHDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHSCPQLSKGTPADERVFLILRVTVQLSHPADMQLVLRKRICVHVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSISSPSMNRLSGSRQELSPSHSLGSNKGRWESQQDVSQTLVSRGIAPGPPALSVSPQNNQSPDPGLGGVAASYLNPVKSLVPQMPKLLKSLFPVRDDRRGRHSSPLAHQPVPRILVQPTFSDTWATRTEEAQQGSPGPSGALESMVKMAAPAVKICDKPVKVSSPPSPMVVTQPPEGQDGPPSPLSEASSGYFSHSVSSATLSETLTLGLDTTGLGSQTPGSPPALCQVTPEPELAFLSCTQSHPPAPEEAHVPAAPTQSTELEVPRAPLLSEPASAVPTSPFRIRKVRTSELKSFTGMLGGASSGAEEDPLASEDPSNARGQTLGRLEVTSDSEDASEVPEWLREGEYVVVGTNKTGIVRYIGPTDFQEGTWIGVELDLPAGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRAVGTGRRRSSGLQPQGAPEVRRSATISGSATNLASLTAALAKGDRSYKNPENRKSWAS", "length": 1847 }, "evidence": [ { "id": "A0A8V0YGI0", "url": "https://omabrowser.org/oma/group/A0A8V0YGI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8M2BH26-1", "protein_name": "Kinesin-like protein KIF13B isoform X1", "gene_name": "kif13ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGDANLNDSNVKVAVRVRPMNRREKDLNTKCVVEMEGNQTFLYSTNLGKDSSRGQPKTFAYDYCFWSMDESETEKFAGQDVVFQCLGESLLHNAFQGYNACIFAYGQTGSGKSYTMMGSVDQPGLIPRLCSSLFERTVLHQREEESFTVEVSYMEIYNEKVRDLLDPKGSRQALRVREHKVLGPYVDGLSRLAVESYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIILTHTLKDLQSGTSGEKVSKLSLVDLAGSERAAKTGAAGERLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSRTAMVATVSPAADNYDETLSTLRYADRAKSIVNHAVVNEDPNARIIRELREEVEKLRDQLTQAESMKAPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGEDKCFLVNLNADPALNELLVYYLKEHTKVGSADSQDIQLCGMGIQAEHCVINITPEGAVFINPYRNSRTCVNGSPVTSRQQLHHGDRILWGNNHFFRINLPKRRLRGEEEEGEGGNMKSSNSNEQLDGEGDTASEVSSEVSFSYEFAQTEVMMKALGSNDPMQAVLQSLERQHEEEKRTALERQRLMYEQELQQLRRQLTPDRQSMQIPQSQPLQPHYRSMERLSQGGMSSSSSAQHRLRQWSEEREVVLTRSLRKLREQIVRANLLVQEASFIAEELDKRTEYRVTLQIPAANLNANRKRDAVLSEPAIQVRRKGKGKQIWALEKMENRLVDMRELYQEWKDFDEDNSVMRSYFKRADPFFDEQVNHSLIGVANVFLSCLFYDVKLQYAVPIINQKGEVAGRLHVEVMRMGGGFDDSVGGGEESDGSPDGDVQERKLVCMIKILQATGLPQYLSNFVFCQYSFWDQAEPIIVAPEVDPSASFSSSKDPHCMVVFDSLKEHAVNVTEEFIEYLTEGAVGIEVYGHRQADPGRNPALWDLSIIQAKTRTLRDRWSEVTRKLEMWVQILELNENGEYMPVEVVPARDVRTGGIFQLKQGQSRRVQVEVRSVQDSGTMPLISEIILGVSIGCVQIRQVPMTKNNEPQEPEGDEMDSYQERDLERLRHQWLTALTKRQEYLDQHLQTLVSKSDKSEDDVEREAQLLEGRLTLTEERNAVMVPSAGSGIPGAPAEWVPVPGMETHIPVLFLDLSADDFSSQENLDVPEAGGWDATLSSEDEDEFFDLQIVKHYDGEVKAEASWDSTVHECQQLSRGATADQRVYLIVRTVVQLSHPAEMQLVLRKRICVNITGRQGFAQNFLRRMSTRSTIPGCGVTFEVVSNIPGQDSQSSEDREMLARVAASAENPKSSDNEAAIEKYLRSVLAVENILTLDRLRQEVAVKEHLAGKGKGSRRSLSSPSVHRLSGSRQDLSLNSVLDDNKNRWESQQDIFATSSGFSKTLPRPSRPPTPPTQSQDPEQGFSGLAASYISPVKALVPQMPKLLKSLFPVRDEKKDLRPSPHSQQHMPRIMMQTANNPDEGRVRIEPVAVMGKSPSSDRHSDAPDAPSSMHDPHDLPLSPISEASSGYFSTSVSTATLSDVSIACGDLTPTPNTQLGSVASRQRGEDSEECLATPVNASIAPVEAGIRSDRHKHEEAAHRNGVTTSQQEAQLQTNPVLSTSTDNPFSLQKVKANELRSFSNILGDGDGKATTNILEKLEITFEDAEPKELAWLKVGGRVTVGTSKSGTVRYIGPTHFSEGVWVGVELDTPSGKNDGSVEGHQYFRCNPGFGVLVRPDRLSRREASKRHNENRRSGEFSQQLRGGTGTAIQKAENRKSWTS", "length": 1822 }, "evidence": [ { "id": "A0A8V0YGI0", "url": "https://omabrowser.org/oma/group/A0A8V0YGI0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LK29-1", "protein_name": "Kinesin family member 13B", "gene_name": "Kif13b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTSSRERRAYFPASASAGLVRTSNPGMPRGAPVLAPRRSRPLSPQPPPAGLASESLSGGRGKRRCSKNPGGSTMGDSKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINTNLSKGDARGQPKIFAYDHCFWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQTSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHGIIDIMPEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEEREASLKNDSSSEQLDADGDSSSEVSSEINFNFEYAQMEVTMKALGSNDPMQSILSSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPERQNCRGVDRLSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREASYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLENRLLDMRDLYQEWKECEEDSPVSRSYFKRADPFYDEQENHSLIGVANVFLETLFYDVKLQYAVPIINQKGEVAGRLHVEVMRLSGAIGERIAGGDDPTEVSSEKEVQENRLVCMVKILQATGLPQHLCHFVFCKYDFWDQQEPVTVAPEVDTSSSPTSKEPQCMVVFDHCSEFSVNITEDFIEYLSEGALAIEVYGHKMNDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVIAAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRSPKTHENIHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKHDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMEAHIPVVFLDLNADDFSSQDNLDDPEAGWDATLTGEEEEEFFELQIVKHHDGEVKAEASWDSAVHNCPQLSKGTPADERVFLILRVAVQLSHPADMQLVLRKRICVHVHGRQGFAQSLLKKMTHRSSIPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENAASADSEACIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLNRRSISSPSMNRLSGSRQELSPSHSLSSNKGRWESQQDVSQTLVSRGIASGPPALSVSPQNNQSPDPGLNPASYLNPVKSLVPQMPKLLKSLFPDRRGRHSSPLVQQPVPRILVQPTFSDARATRTEEAQQGSPGPSGALESMVKMAAPTVKICDKPVRVSSPPSTMVVTQPQEGQDGPPSPLSEASSGYFSHSVSTATLSETLTLGLDTTGLGSQTPGSPPALCQVTQEPELAFLSCTQSHPTDPEEPHIPPATPTQSTELEVPRPPLLSDPTPAVPTSPFRIRKVRPSELTSFTGMLGGASSGAQEDPVVSEDPSHARGQTLGRLEVTSDSEDASEVPEWLREGEYVVVGTNKTGIVRYIGPTDFQEGTWIGVELDLPAGKNDGSIGGKQYFRCNPGYGLLVRPGRVRRAAGTGRRRSSGLQPQGAPEARRSATISGSATNLASLTAALAKGDRSYKNPENRKSWAS", "length": 1917 }, "evidence": [ { "id": "A0A8V0YGI0", "url": "https://omabrowser.org/oma/group/A0A8V0YGI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NQT8-1", "protein_name": "Kinesin-like protein KIF13B", "gene_name": "KIF13B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1826 }, "evidence": [ { "id": "A0A8V0YGI0", "url": "https://omabrowser.org/oma/group/A0A8V0YGI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" }, { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1405, "end_pos": 1407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1447, "end_pos": 1449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1661, "end_pos": 1663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1796, "end_pos": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ] }, { "name": "RPEL1", "type": "synonym", "evidence": [ { "id": "XP_015144800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144800" } ] } ], "protein_names": [ { "name": "Ribulose-phosphate 3-epimerase", "type": "recommended", "evidence": [ { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1/entry#names_and_taxonomy" } ] }, { "name": "5.1.3.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1/entry#names_and_taxonomy" } ] }, { "name": "ribulose-phosphate 3-epimerase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015144800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144800" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144800" } ] }, { "annotation": "Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4F2#function" }, { "database": "UniProtKB", "id": "ARBA00057323", "url": "https://www.uniprot.org/uniprotkb/ARBA00057323#function" }, { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770045", "url": "https://www.ncbi.nlm.nih.gov/gene/770045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770045", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHLMIED", "url": "https://omabrowser.org/oma/group/CHLMIED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4F2", "url": "https://www.orthodb.org/?gene=A0A8V0Y4F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK1", "url": "https://www.orthodb.org/?gene=A0A8V0YHK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11749", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11749", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015144800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13677", "url": "https://www.rhea-db.org/rhea/13677", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGCRIGPSILNSDLAALGAECSRMLDCGADYLHLDVMDGHFVPNITFGHPVVESLRKRLGQEPFFDMHMMVARPEQWVQPMAVAGANQYTFHLEATDGPGALIKDIRENGMKVGLAIKPGTTVEQLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVQWLRTQFPSLDIEVDGGVGPDTIHKCAEAGANMIVSGSAIMKSADPRSVINLLRNVCSEAAQKRCLDR", "length": 228, "header": "tr|A0A8V0YHK1-1|A0A8V0YHK1_CHICK Isoform 1 of Ribulose-phosphate 3-epimerase OS=Gallus gallus OX=9031 GN=RPEL1 PE=1 SV=1 CANONICAL=A0A8V0YHK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4F2/entry", "sequence": { "sequence": "MASGCRIGPSILNSDLAALGAECSRMLDCGADYLHLDVMDGHFVPNITFGHPVVESLRKRLGQEPFFDMHMMVARPEQWVQPMAVAGANQYTFHLEATDGPGALIKDIRENGMKVGLAIKPGTTVEQLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVQWLRTQFPSLDIEVDGGVGPDTIHKCAEAGANMIVSGSAIMKSADPRSVINLLRNVCSEAAQKRCLDRVGNAMV", "length": 234, "header": "tr|A0A8V0Y4F2-1|A0A8V0YHK1_CHICK Computationally mapped isoform of Ribulose-phosphate 3-epimerase OS=Gallus gallus OX=9031 GN=RPEL1 PE=1 SV=1 CANONICAL=A0A8V0YHK1-1" }, "locus": { "chromosome": "7", "start_pos": 2762762, "end_pos": 2761205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027206.1", "url": "https://www.ensembl.org/id/ENSGALT00010027206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015493.1", "url": "https://www.ensembl.org/id/ENSGALP00010015493.1" } ] } }, { "isoform_ac": "A0A8V0YHK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1/entry", "sequence": { "sequence": "MASGCRIGPSILNSDLAALGAECSRMLDCGADYLHLDVMDGHFVPNITFGHPVVESLRKRLGQEPFFDMHMMVARPEQWVQPMAVAGANQYTFHLEATDGPGALIKDIRENGMKVGLAIKPGTTVEQLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVQWLRTQFPSLDIEVDGGVGPDTIHKCAEAGANMIVSGSAIMKSADPRSVINLLRNVCSEAAQKRCLDR", "length": 228, "header": "tr|A0A8V0YHK1-1|A0A8V0YHK1_CHICK Isoform 1 of Ribulose-phosphate 3-epimerase OS=Gallus gallus OX=9031 GN=RPEL1 PE=1 SV=1 CANONICAL=A0A8V0YHK1-1" }, "locus": { "chromosome": "7", "start_pos": 2762561, "end_pos": 2761205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027209.1", "url": "https://www.ensembl.org/id/ENSGALT00010027209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015494.1", "url": "https://www.ensembl.org/id/ENSGALP00010015494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770045", "resource": "KEGG Pathway" }, { "id": "R-GGA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQY9-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "RPE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASGCRIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGPDTIHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR", "length": 228 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MKD3-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "Rpe", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDAPCSSGRSVFLHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATDNPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRSVINLLRNVCSEAAQKRSLDR", "length": 235 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6GEB4-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "Rpe", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFGSLLSTFYLLSSVCPDAMPPSYPTHFFFLDLDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR", "length": 259 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P46969-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "RPE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD", "length": 238 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54YE7-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "rpe", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLKPIICPSLLSSDFAFLARDSNYMLECGADWLHIDVMDNHFVPNLTLGAPIVKSLRKHTKGYFDCHLMVTNPETMIEDFKNAGANSITFHIEATEPRGITQKVITQIKEAGMKVALCVKPKTPIEEVFPYVDQLDFVLIMTVEPGFGGQSFMKDMMPKVKTLRSKYPNLNIQVDGGLDPSTIDMAAEAGANVIVAGSALFKPNQDPKETIKLFKDSINKHSSN", "length": 225 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEE0-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "Rpe", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR", "length": 228 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AT9-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "RPE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR", "length": 228 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C8T3-1", "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVGVSPKIAPSMLSSDFANLAAEAKRMIDLGANWLHMDIMDGHFVSNLTIGAPVIESLRKHTNAYLDCHLMVTNPMDYVDQMAKAGASGFTFHVEVAQENWQELVKKIKAAGMRPGVALKPGTPVEQVYPLVEGTNPVEMVLVMTVEPGFGGQKFMPSMMDKVRALRNKYPTLDIEVDGGLGPSTIDAAAAAGANCIVAGSSVFGAPKPGDVISLLRASVEKAQPST", "length": 227 }, "evidence": [ { "id": "A0A8V0YHK1", "url": "https://omabrowser.org/oma/group/A0A8V0YHK1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "D-ribulose-phosphate 3-epimerase activity", "id": "GO:0004750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "pentose-phosphate shunt, non-oxidative branch", "id": "GO:0009052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" }, { "name": "pentose-phosphate shunt", "id": "GO:0006098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13677", "name": "", "equation": "D-ribulose 5-phosphate = D-xylulose 5-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK1-1" ], "evidence": [ { "id": "13677", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13677" } ] }, { "id": "R-GGA-199803", "name": "RPE dimers isomerize XY5P to RU5P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK1-1" ], "evidence": [ { "id": "R-GGA-199803", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199803" } ] }, { "id": "R-GGA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK1-1" ], "evidence": [ { "id": "R-GGA-71303", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71303" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YHK1", "gene_name": "RPEL1", "activity": [ { "ec_number": "5.1.3.1", "activity": "D-ribulose 5-phosphate = D-xylulose 5-phosphate.", "evidence": [ { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ] }, { "ec_number": "5.1.3.1", "activity": "", "evidence": [ { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "PIRSR001461-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001461-2" }, { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "binding_site_uniprot": 175, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 175, "end_pos": 175, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR001461-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001461-2" }, { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "binding_site_uniprot": 35, "amino_acid": "His", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 35, "end_pos": 35, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR001461-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001461-2" }, { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "binding_site_uniprot": 37, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 37, "end_pos": 37, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR001461-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001461-2" }, { "id": "A0A8V0YHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK1" } ], "binding_site_uniprot": 70, "amino_acid": "His", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 70, "end_pos": 70, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.1.3.1", "ec_name": "D-ribulose 5-phosphate = D-xylulose 5-phosphate.", "evidence": [ { "id": "5.1.3.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.1" }, { "id": "5.1.3.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.1.3.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YI81-1", "uniprot_ac": "A0A8V0YI81", "uniprot_id": "A0A8V0YI81_CHICK", "mass": { "chemical_mass": 54249.0, "monoisotopic_mass": 54249.0 }, "refseq": { "ac": "XP_003643035", "name": "doublesex- and mab-3-related transcription factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643035" }, "gene_names": [ { "name": "DMRT2", "type": "recommended", "evidence": [ { "id": "A0A8V0YI81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ] }, { "name": "DMRT2", "type": "synonym", "evidence": [ { "id": "XP_003643035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643035" } ] } ], "protein_names": [ { "name": "Doublesex and mab-3 related transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YI81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81/entry#names_and_taxonomy" } ] }, { "name": "doublesex- and mab-3-related transcription factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643035" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_003643035.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMRT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81", "locus": { "chromosome": "Z", "start_pos": 26550619, "end_pos": 26545467, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011482", "url": "https://www.ensembl.org/id/ENSGALG00010011482" } ] } } ], "crossref": [ { "id": "A0A8V0YI81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI81", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858556", "url": "https://www.ncbi.nlm.nih.gov/gene/100858556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858556", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDLKGTR", "url": "https://omabrowser.org/oma/group/WDLKGTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y522", "url": "https://www.orthodb.org/?gene=A0A8V0Y522", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBA7", "url": "https://www.orthodb.org/?gene=A0A8V0YBA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI81", "url": "https://www.orthodb.org/?gene=A0A8V0YI81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y522", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y522", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y522-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y522-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGRAAGEWEIDVESLEGEAAEGPGAPREEEEEEGEEAVAVPRRGGGGEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLAGKQASLERKTVYQRHVRTPSLLAKSILEGYRPIPADAYLGGNSPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMMEATQAAALFLPNRMVHGAEYNAYKTAFSPSQVDAPGKEFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLPSRFLVWPKCGPISDALLYQQCLLNATTVQALKPGAGWDTKVAQSPECPNTEQDIMSPKLENPLLLTHTPDIQQACGEVLCLPQEARERSAFSPPKRTFSQISDKDSLTPQEQALGKVSKDTAKPAPPIKYSPFQSLFPQTFPDKSGAELRTSFMKETFEEASKKYRELSIKENQKYKFAIDKCAKDFFGPKQAATKLSAPEPLSFSVESILK", "length": 487, "header": "tr|A0A8V0YI81-1|A0A8V0YI81_CHICK Isoform 1 of Doublesex and mab-3 related transcription factor 2 OS=Gallus gallus OX=9031 GN=DMRT2 PE=3 SV=1 CANONICAL=A0A8V0YI81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y522-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y522/entry", "sequence": { "sequence": "MPAAETRCWKDPCFNGCYRPIPADAYLGGNSPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMMEATQAAALFLPNRMVHGAEYNAYKTAFSPSQVDAPGKEFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLPSRFLVWPKCGPISDALLYQQCLLNATTVQALKPGAGWDTKVAQSPECPNTEQDIMSPKLENPLLLTHTPDIQQACGEVLCLPQEARERSAFSPPKRTFSQISDKDSLTPQEQALGKVSKDTAKPAPPIKYSPFQSLFPQTFPDKSGAELRTSFMKETFEEASKKYRELSIKENQKYKFAIDKCAKDFFGPKQAATKLSAPEPLSFSVESILK", "length": 357, "header": "tr|A0A8V0Y522-1|A0A8V0YI81_CHICK Computationally mapped isoform of Doublesex and mab-3 related transcription factor 2 OS=Gallus gallus OX=9031 GN=DMRT2 PE=3 SV=1 CANONICAL=A0A8V0YI81-1" }, "locus": { "chromosome": "Z", "start_pos": 26549093, "end_pos": 26547032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027488.1", "url": "https://www.ensembl.org/id/ENSGALT00010027488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015735.1", "url": "https://www.ensembl.org/id/ENSGALP00010015735.1" } ] } }, { "isoform_ac": "A0A8V0YBA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBA7/entry", "sequence": { "sequence": "MAAAIGYRPIPADAYLGGNSPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMMEATQAAALFLPNRMVHGAEYNAYKTAFSPSQVDAPGKEFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLPSRFLVWPKCGPISDALLYQQCLLNATTVQALKPGAGWDTKVAQSPECPNTEQDIMSPKLENPLLLTHTPDIQQACGEVLCLPQEARERSAFSPPKRTFSQISDKDSLTPQEQALGKVSKDTAKPAPPIKYSPFQSLFPQTFPDKSGAELRTSFMKETFEEASKKYRELSIKENQKYKFAIDKCAKDFFGPKQAATKLSAPEPLSFSVESILK", "length": 346, "header": "tr|A0A8V0YBA7-1|A0A8V0YI81_CHICK Computationally mapped isoform of Doublesex and mab-3 related transcription factor 2 OS=Gallus gallus OX=9031 GN=DMRT2 PE=3 SV=1 CANONICAL=A0A8V0YI81-1" }, "locus": { "chromosome": "Z", "start_pos": 26549093, "end_pos": 26547437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027491.1", "url": "https://www.ensembl.org/id/ENSGALT00010027491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015737.1", "url": "https://www.ensembl.org/id/ENSGALP00010015737.1" } ] } }, { "isoform_ac": "A0A8V0YI81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81/entry", "sequence": { "sequence": "MAEGRAAGEWEIDVESLEGEAAEGPGAPREEEEEEGEEAVAVPRRGGGGEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLAGKQASLERKTVYQRHVRTPSLLAKSILEGYRPIPADAYLGGNSPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMMEATQAAALFLPNRMVHGAEYNAYKTAFSPSQVDAPGKEFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLPSRFLVWPKCGPISDALLYQQCLLNATTVQALKPGAGWDTKVAQSPECPNTEQDIMSPKLENPLLLTHTPDIQQACGEVLCLPQEARERSAFSPPKRTFSQISDKDSLTPQEQALGKVSKDTAKPAPPIKYSPFQSLFPQTFPDKSGAELRTSFMKETFEEASKKYRELSIKENQKYKFAIDKCAKDFFGPKQAATKLSAPEPLSFSVESILK", "length": 487, "header": "tr|A0A8V0YI81-1|A0A8V0YI81_CHICK Isoform 1 of Doublesex and mab-3 related transcription factor 2 OS=Gallus gallus OX=9031 GN=DMRT2 PE=3 SV=1 CANONICAL=A0A8V0YI81-1" }, "locus": { "chromosome": "Z", "start_pos": 26549093, "end_pos": 26546062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027495.1", "url": "https://www.ensembl.org/id/ENSGALT00010027495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015741.1", "url": "https://www.ensembl.org/id/ENSGALP00010015741.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858556", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480RGK4-1", "protein_name": "Doublesex and mab-3 related transcription factor 2", "gene_name": "DMRT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEGQKGPATDWEIDVESLELEEDSSGLALPAPPGTTQPPADGDGEDDEDAEDEDDEDAEDEGDGEEAGAFPEVPGRLEEQGALAPRPPPAPQASQARAGPPERGANAVCGSEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGNLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLEASQAAALFLPNRMGHGPEYNSYKSAYSPTPVDPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFFVWPKCGPISDTLLYQQCLLNATTSVQTLKPGSSWDLKGARLQEGLGADHDMMPLKLEGSLVLPHTPEGQTLRNDLQGHQTGSERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISKESTRHPLPLKHNPFHSLFQQTLHDKSSPELKTSSVKEAFEEAPKKPRECLVRENQKYTFTIDRCAKDLLVAKQVGTKLSVNEPLSFSVESILKRPSSAITHVSQ", "length": 561 }, "evidence": [ { "id": "A0A8V0YI81", "url": "https://omabrowser.org/oma/group/A0A8V0YI81/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A098-1", "protein_name": "Doublesex and mab-3 related transcription factor 2", "gene_name": "Dmrt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TMEGQAVPGVGDWEIDVESLELEEDGCGTPLRATPQEPSPSTADGEEDEDEEEEDEDAEDEGEGEDSSASPEVPGRPEQPGGLAPRPPPAAQALPAAAVVPERGVTAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEGYRPMTAAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGAFSPSAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGAGWDLKGTRVQDGLSAEHDGMPPKPEGSLVLPQLSEVPTSRTDLQAHQAVPERSAFSPPSRNFSPIVDMDCLAAQGHVLTKISKENTRYPLPLKRNPFHSVFQPTLNDKSGPELKAPFVKEAFEETPKKHRECLVKENPKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAVTPVSQ", "length": 561 }, "evidence": [ { "id": "A0A8V0YI81", "url": "https://omabrowser.org/oma/group/A0A8V0YI81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BC71-1", "protein_name": "Doublesex and mab-3 related transcription factor 2", "gene_name": "DMRT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADGQPGPAVDWEIDVESLELEEDSRGAPPPTPPGPSPPPAYEDDDDAEDEDDVDAEDEGDGEEAAASPGVPGRPERQGALAPRPSTAPQASQAPAGPPERGANAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPPETYVGGSLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLEASQAAALFLPNRMVHGSEYSSYKSAYSPTPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRLLVWPKCGPISDTVLYQQCLLNTTTSVQALKPGTSWDLKGVRLQDGLGADHDMMPPKLEGSLVLPHTPEGHILRSDLQGHQALPERSAFSPPRRNFSPVVDTDTLAAQGHVLTKISKESTRHPLPLKHNPFHSLFQQTHNDKSGPELKTSSVKEAFEEAPKKPRECLVKENQKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITHVSQ", "length": 558 }, "evidence": [ { "id": "A0A8V0YI81", "url": "https://omabrowser.org/oma/group/A0A8V0YI81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BG36-1", "protein_name": "Doublesex- and mab-3-related transcription factor 2", "gene_name": "Dmrt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEGQAVPGVGDWEIDVESLDLEEDSCGTPLRATPPQEPSPAAADGEEDEDEEEEDEDVEDEGDGEEPGVSSEVPGRPEQPGGLAPRPPPAAQALPAAAAAPERGATAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEGYRPMTAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGTYSPTAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGTGWDLKGTRVQDGLSAEQDMMPPKLEGSLVLPHLPEVPASRTDLQVHQVVPERSAFSPPGRNFSPIVDMDCLAAQGHVLTKLSKENTRPSLPLKTNPFHSVFQQTLSDKSGPELNAPFVKEAFEETPKKHRECLVKESQKYTFTIDRCAKDLFVAKQVGTKLSANEPLSFSVESILKRPSSAVTHVSQ", "length": 561 }, "evidence": [ { "id": "A0A8V0YI81", "url": "https://omabrowser.org/oma/group/A0A8V0YI81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5R5-1", "protein_name": "Doublesex- and mab-3-related transcription factor 2", "gene_name": "DMRT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISKENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ", "length": 561 }, "evidence": [ { "id": "A0A8V0YI81", "url": "https://omabrowser.org/oma/group/A0A8V0YI81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI81" }, { "id": "PS50809", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50809" }, { "id": "PRU00070", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DM", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 107, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 }, { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJZ6-1", "uniprot_ac": "A0A8V0YJZ6", "uniprot_id": "A0A8V0YJZ6_CHICK", "mass": { "chemical_mass": 49357.0, "monoisotopic_mass": 49357.0 }, "refseq": {}, "gene_names": [ { "name": "ELK3", "type": "recommended", "evidence": [ { "id": "A0A8V0YJZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ] } ], "protein_names": [ { "name": "ELK3, ETS transcription factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YJZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ELK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6", "locus": { "chromosome": "1", "start_pos": 45847165, "end_pos": 45801686, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011929", "url": "https://www.ensembl.org/id/ENSGALG00010011929" } ] } } ], "crossref": [ { "id": "A0A8V0YJZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6U3", "url": "https://www.orthodb.org/?gene=A0A8V0Y6U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF88", "url": "https://www.orthodb.org/?gene=A0A8V0YF88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YJZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK02", "url": "https://www.orthodb.org/?gene=A0A8V0YK02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y6U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILRKNVFTVRVTKYWNRLPREVVEAPSLEIFKTCLDAFLCMESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKMATESRDVHKHSLSALKSTSRNEYIHSGLYSSFTINSLQNQPDTYKPIKTEKLEEKSEGNTPVEEVRTVIRFVTNKTDKQVMRPMVSLPSTSETAAASAFLSSPVSAKISSLMLPNSASISSPSSSSSRSPSLSPTSPLPSEHRSLFFESSCHDSDSLEPLNLSSGSKAKSPSLPPKAKKPKGLEISAPPLVLSSTDIGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHIPVPLPSLDGASSPVLLSPNAQKS", "length": 448, "header": "tr|A0A8V0YJZ6-1|A0A8V0YJZ6_CHICK Isoform 1 of ELK3, ETS transcription factor OS=Gallus gallus OX=9031 GN=ELK3 PE=3 SV=1 CANONICAL=A0A8V0YJZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6U3/entry", "sequence": { "sequence": "MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKMATESRDVHKHSLSALKSTSRNEYIHSGLYSSFTINSLQNQPDTYKPIKTEKLEEKSEGNTPVEEVRTVIRFVTNKTDKQVMRPMVSLPSTSETAAASAFLSSPVSAKISSLMLPNSASISSPSSSSSGSKAKSPSLPPKAKKPKGLEISAPPLVLSSTDIGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHIPVPLPSLDGASSPVLLSPNAQKS", "length": 370, "header": "tr|A0A8V0Y6U3-1|A0A8V0YJZ6_CHICK Computationally mapped isoform of ELK3, ETS transcription factor OS=Gallus gallus OX=9031 GN=ELK3 PE=3 SV=1 CANONICAL=A0A8V0YJZ6-1" }, "locus": { "chromosome": "1", "start_pos": 45834569, "end_pos": 45819069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028546.1", "url": "https://www.ensembl.org/id/ENSGALT00010028546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016387.1", "url": "https://www.ensembl.org/id/ENSGALP00010016387.1" } ] } }, { "isoform_ac": "A0A8V0YF88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF88/entry", "sequence": { "sequence": "MRRLLGRNAACLQQHWLPCESSVNGGMESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKMATESRDVHKHSLSALKSTSRNEYIHSGLYSSFTINSLQNQPDTYKPIKTEKLEEKSEGNTPVEEVRTVIRFVTNKTDKQVMRPMVSLPSTSETAAASAFLSSPVSAKISSLMLPNSASISSPSSSSSRSPSLSPTSPLPSEHRSLFFESSCHDSDSLEPLNLSSGSKAKSPSLPPKAKKPKGLEISAPPLVLSSTDIGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHIPVPLPSLDGASSPVLLSPNAQKS", "length": 433, "header": "tr|A0A8V0YF88-1|A0A8V0YJZ6_CHICK Computationally mapped isoform of ELK3, ETS transcription factor OS=Gallus gallus OX=9031 GN=ELK3 PE=3 SV=1 CANONICAL=A0A8V0YJZ6-1" }, "locus": { "chromosome": "1", "start_pos": 45834569, "end_pos": 45812341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028544.1", "url": "https://www.ensembl.org/id/ENSGALT00010028544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016385.1", "url": "https://www.ensembl.org/id/ENSGALP00010016385.1" } ] } }, { "isoform_ac": "A0A8V0YJZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6/entry", "sequence": { "sequence": "MILRKNVFTVRVTKYWNRLPREVVEAPSLEIFKTCLDAFLCMESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKMATESRDVHKHSLSALKSTSRNEYIHSGLYSSFTINSLQNQPDTYKPIKTEKLEEKSEGNTPVEEVRTVIRFVTNKTDKQVMRPMVSLPSTSETAAASAFLSSPVSAKISSLMLPNSASISSPSSSSSRSPSLSPTSPLPSEHRSLFFESSCHDSDSLEPLNLSSGSKAKSPSLPPKAKKPKGLEISAPPLVLSSTDIGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPNTLFQFPTLLNGHIPVPLPSLDGASSPVLLSPNAQKS", "length": 448, "header": "tr|A0A8V0YJZ6-1|A0A8V0YJZ6_CHICK Isoform 1 of ELK3, ETS transcription factor OS=Gallus gallus OX=9031 GN=ELK3 PE=3 SV=1 CANONICAL=A0A8V0YJZ6-1" }, "locus": { "chromosome": "1", "start_pos": 45834569, "end_pos": 45816033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028540.1", "url": "https://www.ensembl.org/id/ENSGALT00010028540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016381.1", "url": "https://www.ensembl.org/id/ENSGALP00010016381.1" } ] } }, { "isoform_ac": "A0A8V0YK02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK02/entry", "sequence": { "sequence": "MRRLLGRNAACLQQHWLPCESSVNGGMESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKMATESRDVHKHSLSALKSTSRNEYIHSGLYSSFTINSLQNQPDTYKPIKTEKLEEKSEGNTPVEEVRTVIRFVTNKTDKQVMRPMVSLPSTSETAAASAFLSSPVSAKISSLMLPNSASISSPSSSSSRSPSLSPTSPLPSEHRSLFFESSCHDSDSLEPLNLSSGSKAKSPSLPPKAKKPKGLEISAPPLVLSSTDIGSIALNSPALPSGSLTPAFFTAQTPSGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPNTLFQMYSSHRKSI", "length": 410, "header": "tr|A0A8V0YK02-1|A0A8V0YJZ6_CHICK Computationally mapped isoform of ELK3, ETS transcription factor OS=Gallus gallus OX=9031 GN=ELK3 PE=3 SV=1 CANONICAL=A0A8V0YJZ6-1" }, "locus": { "chromosome": "1", "start_pos": 45846161, "end_pos": 45812341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028547.1", "url": "https://www.ensembl.org/id/ENSGALT00010028547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016388.1", "url": "https://www.ensembl.org/id/ENSGALP00010016388.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "purine-rich negative regulatory element binding", "id": "GO:0032422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032422", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ6" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 126, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFD0-1", "uniprot_ac": "A0A8V0YFD0", "uniprot_id": "A0A8V0YFD0_CHICK", "mass": { "chemical_mass": 34076.0, "monoisotopic_mass": 34076.0 }, "refseq": {}, "gene_names": [ { "name": "NOL12", "type": "recommended", "evidence": [ { "id": "A0A8V0YFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0" } ] } ], "protein_names": [ { "name": "Nucleolar protein 12", "type": "recommended", "evidence": [ { "id": "A0A8V0YFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0", "locus": { "chromosome": "1", "start_pos": 51190705, "end_pos": 51203699, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010890", "url": "https://www.ensembl.org/id/ENSGALG00010010890" } ] } } ], "crossref": [ { "id": "A0A8V0YFD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6W4", "url": "https://www.orthodb.org/?gene=A0A8V0Y6W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YAQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFC6", "url": "https://www.orthodb.org/?gene=A0A8V0YFC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFD0", "url": "https://www.orthodb.org/?gene=A0A8V0YFD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14577:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14577:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y6W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVFFTSSSLAAPPVFAGPKISRLCGLVDSSFSRVSVFSQLRCWGRAVRSRKWSNRKRRGFIGPEEEVDRKWGWRQRGLAMGRKKKGPGSAASRLVVTFDEERRREYLTGFHKRKVERRKVALEEIKRKLKEEQRKMKEERHKEYMKMLREREEALDEFDELEHLVTSRTESVNIDHPNHIVTVTTISDLDLSGARQLGLTTSEGKSDGSEEEKGEEVVNKPARTMPKKSRNPFLSEKISSLTATLHMHSRKKKKGKRPQRGQGPFKKIQKPSTRRTTKTQRRRLTGRMGRDQD", "length": 294, "header": "tr|A0A8V0YFD0-1|A0A8V0YFD0_CHICK Isoform 1 of Nucleolar protein 12 OS=Gallus gallus OX=9031 GN=NOL12 PE=3 SV=1 CANONICAL=A0A8V0YFD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6W4/entry", "sequence": { "sequence": "MGRKKKGPGSAASRLVVTFDEERRREYLTGFHKRKVERRKMKEERHKEYMKMLREREEALDEFDELEHLVTSRTESVNIDHPNHIVTVTTISDLDLSGARQLGLTTSEGKSDGSEEEKGEEVVNKPARTMPKKSRNPFLSEKISSLTATLHMHSRKKKKGKRPQRGQGPFKKIQKPSTRRTTKTQRRRLTGRMGRDQD", "length": 198, "header": "tr|A0A8V0Y6W4-1|A0A8V0YFD0_CHICK Computationally mapped isoform of Nucleolar protein 12 OS=Gallus gallus OX=9031 GN=NOL12 PE=3 SV=1 CANONICAL=A0A8V0YFD0-1" }, "locus": { "chromosome": "1", "start_pos": 51195248, "end_pos": 51191812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026048.1", "url": "https://www.ensembl.org/id/ENSGALT00010026048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014688.1", "url": "https://www.ensembl.org/id/ENSGALP00010014688.1" } ] } }, { "isoform_ac": "A0A8V0YAQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ1/entry", "sequence": { "sequence": "MVLSNTSWEYLTGFHKRKVERRKVALEEIKRKLKEEQRKMKEERHKEYMKMLREREEALDEFDELEHLVTSRTESVNIDHPNHIVTVTTISDLDLSGARQLGLTTSEGKSDGSEEEKGEEVVNKPARTMPKKSRNPFLSEKISSLTATLHMHSRKKKKGKRPQRGQGPFKKIQKPSTRRTTKTQRRRLTGRMGRDQD", "length": 197, "header": "tr|A0A8V0YAQ1-1|A0A8V0YFD0_CHICK Computationally mapped isoform of Nucleolar protein 12 OS=Gallus gallus OX=9031 GN=NOL12 PE=3 SV=1 CANONICAL=A0A8V0YFD0-1" }, "locus": { "chromosome": "1", "start_pos": 51198187, "end_pos": 51191812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026054.1", "url": "https://www.ensembl.org/id/ENSGALT00010026054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014693.1", "url": "https://www.ensembl.org/id/ENSGALP00010014693.1" } ] } }, { "isoform_ac": "A0A8V0YFC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC6/entry", "sequence": { "sequence": "MAQTQQMLKKGHLLPFKTDRCKEMSVFFTSSSLAAPPVFAGPKISRLCGLVDSSFSRVSVFSQLRCWRHKEYMKMLREREEALDEFDELEHLVTSRTESVNIDHPNHIVTVTTISDLDLSGARQLGLTTSEGKSDGSEEEKGEEVVNKPARTMPKKSRNPFLSEKISSLTATLHMHSRKKKKGKRPQRGQGPFKKIQKPSTRRTTKTQRRRLTGRMGRDQD", "length": 221, "header": "tr|A0A8V0YFC6-1|A0A8V0YFD0_CHICK Computationally mapped isoform of Nucleolar protein 12 OS=Gallus gallus OX=9031 GN=NOL12 PE=3 SV=1 CANONICAL=A0A8V0YFD0-1" }, "locus": { "chromosome": "1", "start_pos": 51203585, "end_pos": 51191812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026051.1", "url": "https://www.ensembl.org/id/ENSGALT00010026051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014691.1", "url": "https://www.ensembl.org/id/ENSGALP00010014691.1" } ] } }, { "isoform_ac": "A0A8V0YFD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0/entry", "sequence": { "sequence": "MSVFFTSSSLAAPPVFAGPKISRLCGLVDSSFSRVSVFSQLRCWGRAVRSRKWSNRKRRGFIGPEEEVDRKWGWRQRGLAMGRKKKGPGSAASRLVVTFDEERRREYLTGFHKRKVERRKVALEEIKRKLKEEQRKMKEERHKEYMKMLREREEALDEFDELEHLVTSRTESVNIDHPNHIVTVTTISDLDLSGARQLGLTTSEGKSDGSEEEKGEEVVNKPARTMPKKSRNPFLSEKISSLTATLHMHSRKKKKGKRPQRGQGPFKKIQKPSTRRTTKTQRRRLTGRMGRDQD", "length": 294, "header": "tr|A0A8V0YFD0-1|A0A8V0YFD0_CHICK Isoform 1 of Nucleolar protein 12 OS=Gallus gallus OX=9031 GN=NOL12 PE=3 SV=1 CANONICAL=A0A8V0YFD0-1" }, "locus": { "chromosome": "1", "start_pos": 51203421, "end_pos": 51191812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026057.1", "url": "https://www.ensembl.org/id/ENSGALT00010026057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014696.1", "url": "https://www.ensembl.org/id/ENSGALP00010014696.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFE8-1", "uniprot_ac": "A0A8V0YFE8", "uniprot_id": "A0A8V0YFE8_CHICK", "mass": { "chemical_mass": 45010.0, "monoisotopic_mass": 45010.0 }, "refseq": { "ac": "XP_422261", "name": "torsin-1A-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422261" }, "gene_names": [ { "name": "TOR1AIP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ] }, { "name": "TOR1AIP1", "type": "synonym", "evidence": [ { "id": "XP_422261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422261" } ] } ], "protein_names": [ { "name": "Torsin-1A-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8/entry#names_and_taxonomy" } ] }, { "name": "torsin-1A-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422261" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_422261.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422261" } ] }, { "annotation": "Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y6Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y7#function" }, { "database": "UniProtKB", "id": "ARBA00037580", "url": "https://www.uniprot.org/uniprotkb/ARBA00037580#function" }, { "database": "UniProtKB", "id": "A0A8V0Y6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Z2#function" }, { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOR1AIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8", "locus": { "chromosome": "8", "start_pos": 6068782, "end_pos": 6087610, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010904", "url": "https://www.ensembl.org/id/ENSGALG00010010904" } ] } } ], "crossref": [ { "id": "A0A8V0YFE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "424418", "url": "https://www.ncbi.nlm.nih.gov/gene/424418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424418", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRYHVTP", "url": "https://omabrowser.org/oma/group/PRYHVTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6Y7", "url": "https://www.orthodb.org/?gene=A0A8V0Y6Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6Z2", "url": "https://www.orthodb.org/?gene=A0A8V0Y6Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFE8", "url": "https://www.orthodb.org/?gene=A0A8V0YFE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18843:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18843:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGDGEEQAPPHAPELKHRRKSPRFAAEAEPDSGGAQEGGEPAFGSPGSLTRPPIRACRVVGGSSSSFLPESPAKEKVNDYDVSEPKNPAGDQPNAYTPLKESKADFSEKTQEYHATKSQSRSKFRDQPSTGKQSQHLAKKDGSQSGFPKGWTLLLVLLVSISLFSILWIKGLNLPDATLSIRNTQILQAFRTRMKKLRNTYQSQDPNLWKRTHVFLERHLNTSHLHLEPAILLFTAGQEAEKALRCLSDEIANAFAFSQNGTTIKINGADKAILDSDVVKLEVDDELSSGFREGKKVAVVHRFELLPAGSTLIFYKYCDHENAAFKDVALLLTVLLDEQSLRRSLTLKEVEEKVRDFLWTKFTSSDAPSSFNSIDTDKLSGLWSRISHLVLPVWPEKGLPIEGCT", "length": 406, "header": "tr|A0A8V0YFE8-1|A0A8V0YFE8_CHICK Isoform 1 of Torsin-1A-interacting protein 1 OS=Gallus gallus OX=9031 GN=TOR1AIP1 PE=1 SV=1 CANONICAL=A0A8V0YFE8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y7/entry", "sequence": { "sequence": "MVGDGEEQAPPHAPELKHRRKSPRFAAEAEPDSGGAQEGGSSSSFLPESPAKEKVNDYDVSEPKNPAGDQPNAYTPLKESKADFSEKTQEYHATKSQSRSKFRDQPSTGKQSQHLAKKDGSQSGFPKGWTLLLVLLVSISLFSILWIKGLNLPDATLSIRNTQILQAFRTRMKKLRNTYQSQDPNLWKRTHVFLERHLNTSHLHLEPAILLFTAGQEAEKALRCLSDEIANAFAFSQNGTTIKINGADKAILDSDVVKLEVDDELSSGFREGKKVAVVHRFELLPAGSTLIFYKYCDHENAAFKDVALLLTVLLDEQSLRRSLTLKEVEEKVRDFLWTKFTSSDAPSSFNSIDTDKLSGLWSRISHLVLPVWPEKGLPIEGCT", "length": 383, "header": "tr|A0A8V0Y6Y7-1|A0A8V0YFE8_CHICK Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Gallus gallus OX=9031 GN=TOR1AIP1 PE=1 SV=1 CANONICAL=A0A8V0YFE8-1" }, "locus": { "chromosome": "8", "start_pos": 6076582, "end_pos": 6071572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026079.1", "url": "https://www.ensembl.org/id/ENSGALT00010026079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014714.1", "url": "https://www.ensembl.org/id/ENSGALP00010014714.1" } ] } }, { "isoform_ac": "A0A8V0Y6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Z2/entry", "sequence": { "sequence": "MQEAKVRTCIEHDLPQRSALGCHPSRTVAIGGEPAFGSPGSLTRPPIRACRVVGGSSSSFLPESPAKEKVNDYDVSEPKNPAGDQPNAYTPLKESKADFSEKTQEYHATKSQSRSKFRDQPSTGKQSQHLAKKDGSQSGFPKGWTLLLVLLVSISLFSILWIKGLNLPDATLSIRNTQILQAFRTRMKKLRNTYQSQDPNLWKRTHVFLERHLNTSHLHLEPAILLFTAGQEAEKALRCLSDEIANAFAFSQNGTTIKINGADKAILDSDVVKLEVDDELSSGFREGKKVAVVHRFELLPAGSTLIFYKYCDHENAAFKDVALLLTVLLDEQSLRRSLTLKEVEEKVRDFLWTKFTSSDAPSSFNSIDTDKLSGLWSRISHLVLPVWPEKGLPIEGCT", "length": 398, "header": "tr|A0A8V0Y6Z2-1|A0A8V0YFE8_CHICK Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Gallus gallus OX=9031 GN=TOR1AIP1 PE=1 SV=1 CANONICAL=A0A8V0YFE8-1" }, "locus": { "chromosome": "8", "start_pos": 6076943, "end_pos": 6071572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026084.1", "url": "https://www.ensembl.org/id/ENSGALT00010026084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014719.1", "url": "https://www.ensembl.org/id/ENSGALP00010014719.1" } ] } }, { "isoform_ac": "A0A8V0YFE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8/entry", "sequence": { "sequence": "MVGDGEEQAPPHAPELKHRRKSPRFAAEAEPDSGGAQEGGEPAFGSPGSLTRPPIRACRVVGGSSSSFLPESPAKEKVNDYDVSEPKNPAGDQPNAYTPLKESKADFSEKTQEYHATKSQSRSKFRDQPSTGKQSQHLAKKDGSQSGFPKGWTLLLVLLVSISLFSILWIKGLNLPDATLSIRNTQILQAFRTRMKKLRNTYQSQDPNLWKRTHVFLERHLNTSHLHLEPAILLFTAGQEAEKALRCLSDEIANAFAFSQNGTTIKINGADKAILDSDVVKLEVDDELSSGFREGKKVAVVHRFELLPAGSTLIFYKYCDHENAAFKDVALLLTVLLDEQSLRRSLTLKEVEEKVRDFLWTKFTSSDAPSSFNSIDTDKLSGLWSRISHLVLPVWPEKGLPIEGCT", "length": 406, "header": "tr|A0A8V0YFE8-1|A0A8V0YFE8_CHICK Isoform 1 of Torsin-1A-interacting protein 1 OS=Gallus gallus OX=9031 GN=TOR1AIP1 PE=1 SV=1 CANONICAL=A0A8V0YFE8-1" }, "locus": { "chromosome": "8", "start_pos": 6076582, "end_pos": 6071572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026081.1", "url": "https://www.ensembl.org/id/ENSGALT00010026081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014716.1", "url": "https://www.ensembl.org/id/ENSGALP00010014716.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424418", "resource": "KEGG Pathway" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE8", "url": 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"https://www.ensembl.org/id/ENSGALP00010016441.1" } ] } }, { "isoform_ac": "A0A8V0YK45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK45/entry", "sequence": { "sequence": "MCLEYCSIKLPSPGDQGQQHLEVTVLHTVIIGSLKNEELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "length": 176, "header": "tr|A0A8V0YK45-1|A0A8V0YK45_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 D2 OS=Gallus gallus OX=9031 GN=UBE2D2 PE=3 SV=1 CANONICAL=A0A8V0YFD9-1" }, "locus": { "chromosome": "13", "start_pos": 812460, "end_pos": 790836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028613.1", "url": "https://www.ensembl.org/id/ENSGALT00010028613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016434.1", "url": "https://www.ensembl.org/id/ENSGALP00010016434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" }, { "id": "R-GGA-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" }, { "id": "R-GGA-8866652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866652", "resource": "Reactome", "description": "Synthesis of active ubiquitin: roles of E1 and E2 enzymes" }, { "id": "R-GGA-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" }, { "id": "R-GGA-937041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-937041", "resource": "Reactome", "description": "IKK complex recruitment mediated by RIP1" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1234163", "name": "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C8C0-1", "A0A8V0YY10-1", "A0A8V0XX07-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-1234163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234163" } ] }, { "id": "R-GGA-1234172", "name": "Nuclear VBC complex ubiquitinylates HIF-alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-1234172", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234172" } ] }, { "id": "R-GGA-168915", "name": "K63-linked ubiquitination of RIP1 bound to the activated TLR complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-168915", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168915" } ] }, { "id": "R-GGA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8852127", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8852127" } ] }, { "id": "R-GGA-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "R4GIV8-1", "A0A8V1A052-1", "A0A8V1A5P4-1", "A0A8V0Z1W7-1", "A0A8V1A4H7-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8852129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8852129" } ] }, { "id": "R-GGA-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V1A052-1", "A0A8V0Z082-1", "A0A8V1A4H7-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8852130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8852130" } ] }, { "id": "R-GGA-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0ZC97-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8953917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953917" } ] }, { "id": "R-GGA-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0ZC97-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8953946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953946" } ] }, { "id": "R-GGA-8956106", "name": "VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8956106", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8956106" } ] }, { "id": "R-GGA-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0ZC97-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9033485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033485" } ] }, { "id": "R-GGA-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YY10-1", "A0A8V0ZC97-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9033527", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033527" } ] }, { "id": "R-GGA-9815507", "name": "MIB2 ubiquitinates CYLD at K338, K530", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZJV9-1", "A0A8V0ZJC8-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9815507", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9815507" } ] }, { "id": "R-GGA-9815510", "name": "MIB2 binds CYLD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZJV9-1", "A0A8V0ZJC8-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9815510", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9815510" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V0YPW4-1", "Q5ZKX6-1", "R4GIV8-1", "A0A8V0ZBK2-1", "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0Z082-1", "A0A8V0YY10-1", "A0A8V0Z1W7-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V1ACU3-1", "A0A8V0Y059-1", "A0A8V0YFD9-1", "A0A1D5NVE2-1" ], "evidence": [ { "id": "R-GGA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983152" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] }, { "id": "R-GGA-9948301", "name": "ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPA9-1", "A0A8V0YY10-1", "A0A8V0YZ50-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9948301", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9948301" } ] }, { "id": "R-GGA-9948317", "name": "ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPA9-1", "A0A8V0YY10-1", "A0A8V0YZ50-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9948317", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9948317" } ] }, { "id": "R-GGA-9954721", "name": "NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 K48 polyubiquitinates alanine-tailed nascent peptide", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9954721", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954721" } ] }, { "id": "R-GGA-9954727", "name": "RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9954727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954727" } ] }, { "id": "R-GGA-9954737", "name": "RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-9954737", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954737" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XNP1", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0XX07", "gene_name": "EGLN1", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0A8V0XX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX07" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0A8V0XX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX07" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0YZ50", "gene_name": "ZNF598", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ50" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ50" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZBK2", "gene_name": "UBA3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJC8", "gene_name": "CYLD", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0A8V0ZJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJC8" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0A8V0ZJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJC8" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C8C0", "gene_name": "EGLN3", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "E1C8C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8C0" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "E1C8C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8C0" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFX7-1", "uniprot_ac": "A0A8V0YFX7", "uniprot_id": "A0A8V0YFX7_CHICK", "mass": { "chemical_mass": 107276.0, "monoisotopic_mass": 107276.0 }, "refseq": {}, "gene_names": [ { "name": "PGAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ] } ], "protein_names": [ { "name": "GPI inositol-deacylase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7/entry#names_and_taxonomy" } ] }, { "name": "3.1.-.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GPI inositol-deacylase that catalyzes the remove of the acyl chain linked to the 2-OH position of inositol ring from the GPI-anchored protein (GPI-AP) in the endoplasmic reticulum. Initiates the post-attachment remodeling phase of GPI-AP biogenesis and participates in endoplasmic reticulum (ER)-to-Golgi transport of GPI-anchored protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7#function" }, { "database": "UniProtKB", "id": "RU365011", "url": "https://www.uniprot.org/uniprotkb/RU365011#function" }, { "database": "UniProtKB", "id": "ARBA00093318", "url": "https://www.uniprot.org/uniprotkb/ARBA00093318#function" }, { "database": "UniProtKB", "id": "A0A8V0Y7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7H0#function" }, { "database": "UniProtKB", "id": "A0A8V0YB96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB96#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7", "locus": { "chromosome": "7", "start_pos": 9622497, "end_pos": 9659675, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010973", "url": "https://www.ensembl.org/id/ENSGALG00010010973" } ] } } ], "crossref": [ { "id": "A0A8V0YFX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7H0", "url": "https://www.orthodb.org/?gene=A0A8V0Y7H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB96", "url": "https://www.orthodb.org/?gene=A0A8V0YB96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX7", "url": "https://www.orthodb.org/?gene=A0A8V0YFX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15495", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15495", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15495:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15495:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24660", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24660", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "83663", "url": "https://www.rhea-db.org/rhea/83663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83787", "url": "https://www.rhea-db.org/rhea/83787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRVGRRLPAVAAVLYGALAALVLLGVRDVLFVYEENRCSMTYMYEYPEYLKIKLPKKTARRYPAYELYLYGEGNYAEENKNLILTGIPILFLPGNAGSYKQVRSLGSIALRKAEDLDFKYHFNFFSVNFNEELVALYGGTLQRQTKFVHECLKVILKLYRGQEFAPTSVAIVGHSMGGLVARALLTLKNFKPELINLLITQATPHVAPVMPLDRYLTDFYAAVNNHWILKAQDLRNLTTLSVAGGFRDYQVRSGLAFLPRLSQHDSALSVVSSAVPRAWASTDHLSIVWCKELILATIRAFFDLIDENTRQITEDPKKRMSVLNHHFVRHPGKIFEENPEAFTELTGVQQFPPEQDPVILLGTFAWIKVKTSKWTYSVYNDSDGKYFTFPLASHRESYSHIYCENTMLDTSSWIYGCMNSNSSVCLEATDLSWRAELLPTIKVVILKLQDYPSLSHIVILVPPSAGNKFTLDCEFFKEDSRTIQLPVTNLFSFGLSSSKILLNSSGLFYNVQLQHFNQVYQAFKIHVESHCQSLIERKPSVYRLHIPWSHEDSVTVVNVPSFTEISAKLHIAQPENESRVPVLNIYSSSDCQYEVILKTSFLQVLGQIIRFHAGALPVYVVSNILLTYGGQLNTLMSTGQCSEFSLELVRTAKPYKVEPIISIVVFLQGFNWFREIWDSLLLPEVDAAVLSSQDAWFPLVSLILFLFGTGIAYWSAVFFSTSLRIFSSLWLTLTRPTVLSKAKLITPRRLCMVGSLALVSWTTCGAFALFIIYLQYLVKVIKLSVNVRAEQNVLNRDLDHSKETSQNSIGCTVKNQDLIDSTSGATQSLSSSTTAEAANTLKIHVTVLNLFTWIVLLNLPSLVYWLKNLRYSVRLDPDPCRTTAIILVCILEILMNSSTSEMKSSQLLKIAAKVPLLLSVAALAFGRMHLYKVPHFVTFSLLLHLLCCFV", "length": 951, "header": "tr|A0A8V0YFX7-1|A0A8V0YFX7_CHICK Isoform 1 of GPI inositol-deacylase OS=Gallus gallus OX=9031 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A8V0YFX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7H0/entry", "sequence": { "sequence": "MGRVGRRLPAVAAVLYGALAALVLLGVRDVLFVYEENRCSMTYMYEYPEYLKIKLPKKTARRYPAYELYLYGEGNYAEENKNLILTGIPILFLPGNAGSYKQVRSLGSIALRKAEDLDFKYHFNFFSVNFNEELVALYGGTLQRQTKFVHECLKVILKLYRGQEFAPTSVAIVGHSMGGLVARALLTLKNFKPELINLLITQATPHVAPVMPLDRYLTDFYAAVNNHWILKAQDLRNLTTLSVAGGFRDYQVRSGLAFLPRLSQHDSALSVVSSAVPRAWASTDHLSIVWCKELILATIRAFFDLIDENTRQITEDPKKRMSVLNHHFVRHPGKIFEENPEAFTELTGTFAWIKVKTSKWTYSVYNDSDGKYFTFPLASHRESYSHIYCENTMLDTSSWIYGCMNSNSSVCLEATDLSWRAELLPTIKVVILKLQDYPSLSHIVILVPPSAGNKFTLDCEFFKEDSRTIQLPVTNLFSFGLSSSKILLNSSGLFYNVQLQHFNQVYQAFKIHVESHCQSLIERKPSVYRLHIPWSHEDSVTVVNVPSFTEISAKLHIAQPENESRVPVLNIYSSSDCQYEVILKTSFLQVLGQIIRFHAGALPVYVVSNILLTYGGQLNTLMSTGQCSEFSLELVRTAKPYKVEPIISIVVFLQGFNWFREIWDSLLLPEVDAAVLSSQDAWFPLVSLILFLFGTGIAYWSAVFFSTSLRIFSSLWLTLTRPTVLSKAKLITPRRLCMVGSLALVSWTTCGAFALFIIYLQYLVKVIKLSVNVRAEQNVLNRDLDHSKETSQNSIGCTVKNQDLIDSTSGATQSLSSSTTAEAANTLKIHVTVLNLFTWIVLLNLPSLVYWLKNLRYSVRLDPDPCRTTAIILVCILEILMNSSTSEMKSRRK", "length": 893, "header": "tr|A0A8V0Y7H0-1|A0A8V0YFX7_CHICK Computationally mapped isoform of GPI inositol-deacylase OS=Gallus gallus OX=9031 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A8V0YFX7-1" }, "locus": { "chromosome": "7", "start_pos": 9659632, "end_pos": 9630823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026278.1", "url": "https://www.ensembl.org/id/ENSGALT00010026278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014902.1", "url": "https://www.ensembl.org/id/ENSGALP00010014902.1" } ] } }, { "isoform_ac": "A0A8V0YB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB96/entry", "sequence": { "sequence": "MGRVGRRLPAVAAVLYGALAALVLLGVRDVLFVYEENRCSMTYMYEYPEYLKIKLPKKTARRYPAYELYLYGEGNYAEENKNLILTGIPILFLPGNAGSYKQVRSLGSIALRKAEDLDFKYHFNFFSVNFNEELVALYGGTLQRQTKFVHECLKVILKLYRGQEFAPTSVAIVGHSMGGLVARALLTLKNFKPELINLLITQATPHVAPVMPLDRYLTDFYAAVNNHWILKAQDLRNLTTLSVAGGFRDYQVRSGLAFLPRLSQHDSALSVVSSAVPRAWASTDHLSIVWCKELILATIRAFFDLIDENTRQITEDPKKRMSVLNHHFVRHPGKIFEENPEAFTELTGTFAWIKVKTSKWTYSVYNDSDGKYFTFPLASHRESYSHIYCENTMLDTSSWIYGCMNSNSSVCLEATDLSWRAELLPTIKVVILKLQDYPSLSHIVILVPPSAGNKFTLDCEFFKEDSRTIQLPVTNLFSFGLSSSKILLNSSGLFYNVQLQHFNQVYQAFKIHVESHCQSLIERKPSVYRLHIPWSHEDSVTVVNVPSFTEISAKLHIAQPENESRVPVLNIYSSSDCQYEVILKTSFLQVLGQIIRFHAGALPVYVVSNILLTYGGQLNTLMSTGQCSEFSLELVRTAKPYKVEPIISIVVFLQGFNWFREIWDSLLLPEVDAAVLSSQDAWFPLVSLILFLFGTGIAYWSAVFFSTSLRIFSSLWLTLTRPTVLSKAKLITPRRLCMVGSLALVSWTTCGAFALFIIYLQYLVKVIKLSVNVRAEQNVLNRDLDHSKETSQNSIGCTVKNQDLIDSTSGATQSLSSSTTAEAANTLKIHVTVLNLFTWIVLLNLPSLVYWLKNLRYSVRLDPDPCRTTAIILVCILEILMNSSTSEMKSSQLLKIAAKVPLLLSVAALAFGRMHLYKNKAFTVSRELV", "length": 929, "header": "tr|A0A8V0YB96-1|A0A8V0YFX7_CHICK Computationally mapped isoform of GPI inositol-deacylase OS=Gallus gallus OX=9031 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A8V0YFX7-1" }, "locus": { "chromosome": "7", "start_pos": 9659632, "end_pos": 9622714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026287.1", "url": "https://www.ensembl.org/id/ENSGALT00010026287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014911.1", "url": "https://www.ensembl.org/id/ENSGALP00010014911.1" } ] } }, { "isoform_ac": "A0A8V0YFX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7/entry", "sequence": { "sequence": "MGRVGRRLPAVAAVLYGALAALVLLGVRDVLFVYEENRCSMTYMYEYPEYLKIKLPKKTARRYPAYELYLYGEGNYAEENKNLILTGIPILFLPGNAGSYKQVRSLGSIALRKAEDLDFKYHFNFFSVNFNEELVALYGGTLQRQTKFVHECLKVILKLYRGQEFAPTSVAIVGHSMGGLVARALLTLKNFKPELINLLITQATPHVAPVMPLDRYLTDFYAAVNNHWILKAQDLRNLTTLSVAGGFRDYQVRSGLAFLPRLSQHDSALSVVSSAVPRAWASTDHLSIVWCKELILATIRAFFDLIDENTRQITEDPKKRMSVLNHHFVRHPGKIFEENPEAFTELTGVQQFPPEQDPVILLGTFAWIKVKTSKWTYSVYNDSDGKYFTFPLASHRESYSHIYCENTMLDTSSWIYGCMNSNSSVCLEATDLSWRAELLPTIKVVILKLQDYPSLSHIVILVPPSAGNKFTLDCEFFKEDSRTIQLPVTNLFSFGLSSSKILLNSSGLFYNVQLQHFNQVYQAFKIHVESHCQSLIERKPSVYRLHIPWSHEDSVTVVNVPSFTEISAKLHIAQPENESRVPVLNIYSSSDCQYEVILKTSFLQVLGQIIRFHAGALPVYVVSNILLTYGGQLNTLMSTGQCSEFSLELVRTAKPYKVEPIISIVVFLQGFNWFREIWDSLLLPEVDAAVLSSQDAWFPLVSLILFLFGTGIAYWSAVFFSTSLRIFSSLWLTLTRPTVLSKAKLITPRRLCMVGSLALVSWTTCGAFALFIIYLQYLVKVIKLSVNVRAEQNVLNRDLDHSKETSQNSIGCTVKNQDLIDSTSGATQSLSSSTTAEAANTLKIHVTVLNLFTWIVLLNLPSLVYWLKNLRYSVRLDPDPCRTTAIILVCILEILMNSSTSEMKSSQLLKIAAKVPLLLSVAALAFGRMHLYKVPHFVTFSLLLHLLCCFV", "length": 951, "header": "tr|A0A8V0YFX7-1|A0A8V0YFX7_CHICK Isoform 1 of GPI inositol-deacylase OS=Gallus gallus OX=9031 GN=PGAP1 PE=1 SV=1 CANONICAL=A0A8V0YFX7-1" }, "locus": { "chromosome": "7", "start_pos": 9659632, "end_pos": 9630617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026285.1", "url": "https://www.ensembl.org/id/ENSGALT00010026285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014909.1", "url": "https://www.ensembl.org/id/ENSGALP00010014909.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" }, { "name": "deacylase activity", "id": "GO:0160215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160215", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 897, "end_pos": 899, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83663", "name": "", "equation": "[protein]-C-terminal carboxyl phosphoethanolamide-GPI(H8) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-GPI(deacylinositol-H8) + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFX7-1" ], "evidence": [ { "id": "83663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83663" } ] }, { "id": "83787", "name": "", "equation": "[protein]-C-terminal carboxyl phosphoethanolamide-GPI(H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-GPI(deacylinositol-H7) + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFX7-1" ], "evidence": [ { "id": "83787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83787" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YFX7", "gene_name": "PGAP1", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" }, { "id": "PF07819", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07819" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI inositol-deacylase PGAP1-like alpha/beta", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 304, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YFX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX7" }, { "id": "PF25140", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI inositol-deacylase transmembrane", "eco_id": "ECO_0000259", "start_pos": 616, "end_pos": 950, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 897, "end_pos": 899 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFZ7-1", "uniprot_ac": "A0A8V0YFZ7", "uniprot_id": "A0A8V0YFZ7_CHICK", "mass": { "chemical_mass": 214084.0, "monoisotopic_mass": 214084.0 }, "refseq": {}, "gene_names": [ { "name": "PTPRD", "type": "recommended", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ], "protein_names": [ { "name": "Receptor-type tyrosine-protein phosphatase S", "type": "recommended", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPRD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7", "locus": { "chromosome": "Z", "start_pos": 29202134, "end_pos": 29561525, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012063", "url": "https://www.ensembl.org/id/ENSGALG00010012063" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05739", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05739", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14628", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14628", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431602", "url": "https://www.ncbi.nlm.nih.gov/gene/431602", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7M0", "url": "https://www.orthodb.org/?gene=A0A8V0Y7M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDT5", "url": "https://www.orthodb.org/?gene=A0A8V0YDT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDU0", "url": "https://www.orthodb.org/?gene=A0A8V0YDU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YFZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YFZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKR4", "url": "https://www.orthodb.org/?gene=A0A8V0YKR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y7M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIELSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYMIQLKPKNSEEPYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIGNLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTISSYELVYKDGEHGEEQRVSTEPTTSYRLQGLKPNSLYLFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWKPPPVENQNGIITAYSIKYIEIDGEDVKPHEILGISSDSTQYLLEQLEKWTEYRISVTAHTDVGPGPESLAVLIRTDEDVPSGPPRKVEVEAVNSTAVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDIMLADAQEMIISGLQPDTTYSFTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVISHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDVDAFTTMEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEIVKEISVPEEVPSGFPQNLHSESSTSTSVQLTWQMPLLAERNGIITKYTILYRDINVAYQPVELPVVPADTTMTLSGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSALPFKILYDDGKMVMEVDGRATQKLITNLKPETSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPVFIGKTNLDGMITVELPEVPSNENIKGYYIVIVPLKRSRGKFIKPWESPDEMELDELLKEIARKRRSIRFGREAELKPYIAAHFEVLPTEFTLGDKKHYGGFENKQLQSGQEYVFFVLAVMEHSESTMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSIPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFVDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT", "length": 1911, "header": "tr|A0A8V0YFZ7-1|A0A8V0YFZ7_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7M0/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIELSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYMIQLKPKNSEEPYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIGNLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTISSYELVYKDGEHGEEQRVSTEPTTSYRLQGLKPNSLYLFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSALPFKILYDDGKMVMEVDGRATQKLITNLKPETSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPVFIGKTNLDGMITVELPEVPSNENIKGYYIVIVPLKRSRGKFIKPWESPDEMELDELLKEIARKRRSIRFGREAELKPYIAAHFEVLPTEFTLGDKKHYGGFENKQLQSGQEYVFFVLAVMEHSESTMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSIPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFVDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT", "length": 1509, "header": "tr|A0A8V0Y7M0-1|A0A8V0YFZ7_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29203976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028907.1", "url": "https://www.ensembl.org/id/ENSGALT00010028907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016666.1", "url": "https://www.ensembl.org/id/ENSGALP00010016666.1" } ] } }, { "isoform_ac": "A0A8V0YDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT5/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSGALQIELSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYMIQLKPKNSEEPYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIGNLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTISSYELVYKDGEHGEEQRVSTEPTTSYRLQGLKPNSLYLFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWKPPPVENQNGIITAYSIKYIEIDGEDVKPHEILGISSDSTQYLLEQLEKWTEYRISVTAHTDVGPGPESLAVLIRTDEDVPSGPPRKVEVEAVNSTAVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDIMLADAQWEYDDTTEHEMIISGLQPDTTYSFTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVISHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDVDAFTTMEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEIVKEISVPEEVPSGFPQNLHSESSTSTSVQLTWQMPLLAERNGIITKYTILYRDINVAYQPVELPVVPADTTMTLSGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQAVFAKNFHVKAVMKTSVLLSWEIPENYNSALPFKILYDDGKMVMEVDGRATQKLITNLKPETSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPVFIGKTNLDGMITVELPEVPSNENIKGYYIVIVPLKRSRGKFIKPWESPDEMELDELLKEIARKRRSIRFGREAELKPYIAAHFEVLPTEFTLGDKKHYGGFENKQLQSGQEYVFFVLAVMEHSESTMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFVDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT", "length": 1907, "header": "tr|A0A8V0YDT5-1|A0A8V0YFZ7_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29203976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028899.1", "url": "https://www.ensembl.org/id/ENSGALT00010028899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016658.1", "url": "https://www.ensembl.org/id/ENSGALP00010016658.1" } ] } }, { "isoform_ac": "A0A8V0YDU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU0/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSGALQIELSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYMIQLKPKNSEEPYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIGNLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTISSYELVYKDGEHGEEQRVSTEPTTSYRLQGLKPNSLYLFRLAARSPQGLGASTAEISARTMQSIPSGPPRKVEVEAVNSTAVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDIMLADAQWEYDDTTEHEMIISGLQPDTTYSFTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVISHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDVDAFTTMEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEIVKEISVPEEVPSGFPQNLHSESSTSTSVQLTWQMPLLAERNGIITKYTILYRDINVAYQPVELPVVPADTTMTLSGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSALPFKILYDDGKMVMEVDGRATQKLITNLKPETSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPVFIGKTNLDGMITVELPEVPSNENIKGYYIVIVPLKRSRGKFIKPWESPDEMELDELLKEIARKRRSIRFGREAELKPYIAAHFEVLPTEFTLGDKKHYGGFENKQLQSGQEYVFFVLAVMEHSESTMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSIPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFVDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT", "length": 1808, "header": "tr|A0A8V0YDU0-1|A0A8V0YFZ7_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29203976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028904.1", "url": "https://www.ensembl.org/id/ENSGALT00010028904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016663.1", "url": "https://www.ensembl.org/id/ENSGALP00010016663.1" } ] } }, { "isoform_ac": "A0A8V0YFZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ1/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSESIGKCLVLKRTSPPLISIFKI", "length": 209, "header": "tr|A0A8V0YFZ1-1|A0A8V0YFZ7_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29346798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028890.1", "url": "https://www.ensembl.org/id/ENSGALT00010028890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016649.1", "url": "https://www.ensembl.org/id/ENSGALP00010016649.1" } ] } }, { "isoform_ac": "A0A8V0YFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIELSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYMIQLKPKNSEEPYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIGNLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTISSYELVYKDGEHGEEQRVSTEPTTSYRLQGLKPNSLYLFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWKPPPVENQNGIITAYSIKYIEIDGEDVKPHEILGISSDSTQYLLEQLEKWTEYRISVTAHTDVGPGPESLAVLIRTDEDVPSGPPRKVEVEAVNSTAVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDIMLADAQEMIISGLQPDTTYSFTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVISHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDVDAFTTMEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEIVKEISVPEEVPSGFPQNLHSESSTSTSVQLTWQMPLLAERNGIITKYTILYRDINVAYQPVELPVVPADTTMTLSGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSALPFKILYDDGKMVMEVDGRATQKLITNLKPETSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPVFIGKTNLDGMITVELPEVPSNENIKGYYIVIVPLKRSRGKFIKPWESPDEMELDELLKEIARKRRSIRFGREAELKPYIAAHFEVLPTEFTLGDKKHYGGFENKQLQSGQEYVFFVLAVMEHSESTMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSIPNSKEVPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFVDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT", "length": 1911, "header": "tr|A0A8V0YFZ7-1|A0A8V0YFZ7_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29203976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028896.1", "url": "https://www.ensembl.org/id/ENSGALT00010028896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016654.1", "url": "https://www.ensembl.org/id/ENSGALP00010016654.1" } ] } }, { "isoform_ac": "A0A8V0YKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR4/entry", "sequence": { "sequence": "MLVPSSWMMHVVRPVVVLLCFLLCADAETPPKFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGEISVSTRLTVLRGPNFGHSGTPFSPRPGKELQGMARPVQCHPGQARQGMARPGMAKLVSCSQFRLICNVFILIICCFILKNEYETITSKSVICLLISIFNTEYK", "length": 216, "header": "tr|A0A8V0YKR4-1|A0A8V0YFZ7_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase S OS=Gallus gallus OX=9031 GN=PTPRD PE=3 SV=1 CANONICAL=A0A8V0YFZ7-1" }, "locus": { "chromosome": "Z", "start_pos": 29476467, "end_pos": 29355521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028888.1", "url": "https://www.ensembl.org/id/ENSGALT00010028888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016647.1", "url": "https://www.ensembl.org/id/ENSGALP00010016647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine morphogenesis", "id": "GO:0061003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "presynaptic membrane assembly", "id": "GO:0097105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "regulation of postsynaptic density assembly", "id": "GO:0099151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" }, { "name": "trans-synaptic signaling by trans-synaptic complex", "id": "GO:0099545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099545", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1502, "end_pos": 1504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1639, "end_pos": 1641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1700, "end_pos": 1702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1735, "end_pos": 1737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-GGA-388824", "name": "PTPRF, PTPRS, PTPRD bind Liprins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB05-1", "A0A3Q2TZZ7-1", "A0A8V0YFZ7-1" ], "evidence": [ { "id": "R-GGA-388824", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388824" } ] }, { "id": "R-GGA-6797803", "name": "PTPRD binds SLITRK1-6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFZ7-1" ], "evidence": [ { "id": "R-GGA-6797803", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6797803" } ] }, { "id": "R-GGA-6797810", "name": "PTPRD binds IL1RAPL1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFZ7-1" ], "evidence": [ { "id": "R-GGA-6797810", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6797810" } ] }, { "id": "R-GGA-6800380", "name": "PTPRD binds IL1RAP-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFZ7-1" ], "evidence": [ { "id": "R-GGA-6800380", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800380" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": 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"ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": 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}, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLC1-1", "uniprot_ac": "A0A8V0YLC1", "uniprot_id": "A0A8V0YLC1_CHICK", "mass": { "chemical_mass": 102650.0, "monoisotopic_mass": 102650.0 }, "refseq": { "ac": "XP_040561332", "name": "ATP-dependent DNA helicase DDX11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561332" }, "gene_names": [ { "name": "DDX11", "type": "recommended", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "name": "DDX11", "type": "synonym", "evidence": [ { "id": "XP_040561332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561332" } ] } ], "protein_names": [ { "name": "ATP-dependent DNA helicase DDX11", "type": "recommended", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.3", "type": "synonym", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent DNA helicase DDX11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040561332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561332" } ] }, { "name": "DEAD/H-box protein 11", "type": "synonym", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1/entry#names_and_taxonomy" } ] }, { "name": "DNA 5'-3' helicase DDX11", "type": "synonym", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDX11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1", "locus": { "chromosome": "1", "start_pos": 59991935, "end_pos": 59970874, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012138", "url": "https://www.ensembl.org/id/ENSGALG00010012138" } ] } } ], "crossref": [ { "id": "A0A8V0YLC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18788", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18788", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418144", "url": "https://www.ncbi.nlm.nih.gov/gene/418144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QTHQFRD", "url": "https://omabrowser.org/oma/group/QTHQFRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLC1", "url": "https://www.orthodb.org/?gene=A0A8V0YLC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11472", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11472", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11472:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11472:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040561332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y856", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y856", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y856-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y856-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y861", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y861", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y861-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y861-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDPSPTSAAVSGPGRASFPFPYTPYRIQEQFMAALYAALEAGRIGIFESPTGTGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQNLCVNEEVRRLGALQLINDRCTEMQKNKHEKKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGPLQSPPVEADSDQLRAASPLMHIEGFLSALTNANEDGRVILNRQGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 910, "header": "tr|A0A8V0YLC1-1|A0A8V0YLC1_CHICK Isoform 1 of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y856-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y856/entry", "sequence": { "sequence": "MDGGTAEGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQNLCVNEEVRRLGALQLINDRCTEMQKNKHEKKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGPLQSPPVEADSDQLRAASPLMHIEGFLSALTNANEDGRVILNRQGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 863, "header": "tr|A0A8V0Y856-1|A0A8V0YLC1_CHICK Computationally mapped isoform of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "locus": { "chromosome": "1", "start_pos": 59991656, "end_pos": 59972424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029119.1", "url": "https://www.ensembl.org/id/ENSGALT00010029119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016878.1", "url": "https://www.ensembl.org/id/ENSGALP00010016878.1" } ] } }, { "isoform_ac": "A0A8V0Y861-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y861/entry", "sequence": { "sequence": "MDGGTAEAVSGPGRASFPFPYTPYRIQEQFMAALYAALEAGRIGIFESPTGTGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQNLCVNEEVRRLGALQLINDRCTEMQKNKHEKKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGPLQSPPVEADSDQLRAASPLMHIEGFLSALTNANEDGRVILNRQGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 908, "header": "tr|A0A8V0Y861-1|A0A8V0YLC1_CHICK Computationally mapped isoform of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "locus": { "chromosome": "1", "start_pos": 59991656, "end_pos": 59972424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029125.1", "url": "https://www.ensembl.org/id/ENSGALT00010029125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016883.1", "url": "https://www.ensembl.org/id/ENSGALP00010016883.1" } ] } }, { "isoform_ac": "A0A8V0YEE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE1/entry", "sequence": { "sequence": "MDGGTAEAVSGPGRASFPFPYTPYRIQEQFMAALYAALEAGRIGIFESPTGTGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQNLCVNEEVRRLGALQLINDRCTEMQKNKHEKKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 863, "header": "tr|A0A8V0YEE1-1|A0A8V0YLC1_CHICK Computationally mapped isoform of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "locus": { "chromosome": "1", "start_pos": 59991656, "end_pos": 59972424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029116.1", "url": "https://www.ensembl.org/id/ENSGALT00010029116.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016875.1", "url": "https://www.ensembl.org/id/ENSGALP00010016875.1" } ] } }, { "isoform_ac": "A0A8V0YGK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK0/entry", "sequence": { "sequence": "MDGGTAEAVSGPGRASFPFPYTPYRIQEQFMAALYAALEAGRIGIFESPTGTGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGPLQSPPVEADSDQLRAASPLMHIEGFLSALTNANEDGRVILNRQGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 877, "header": "tr|A0A8V0YGK0-1|A0A8V0YGK0_CHICK Computationally mapped isoform of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "locus": { "chromosome": "1", "start_pos": 59991656, "end_pos": 59972424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029123.1", "url": "https://www.ensembl.org/id/ENSGALT00010029123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016881.1", "url": "https://www.ensembl.org/id/ENSGALP00010016881.1" } ] } }, { "isoform_ac": "A0A8V0YLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1/entry", "sequence": { "sequence": "MRDPSPTSAAVSGPGRASFPFPYTPYRIQEQFMAALYAALEAGRIGIFESPTGTGKSLSLICGALSWLQDFEKKKQEEEARLLAPEGSGQEEKQTLASGGLACPNSRDASGEPDWVTAFVQKKEEQDLVHRLKEEQIRRKKREERLEKIRHNVQLKYAAKRKRSEEDETKRLLQLSKEILSEGAGAAVPEQLDHNEEELILAEYESDEEKKVASGLEEDDDDDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKDTRLVSLGSRQNLCVNEEVRRLGALQLINDRCTEMQKNKHEKKSDAEVEGKKRRVSRTVCPFYSYEQMQFLRDEVLVEVKDIEQLVTLGKETKACPYYGSRYAIPAAQLVVLPYQMLLHEATRSAAGIILKDQVVIIDEAHNLIDTITCIYSAEVSGSQLCCAHSQLLQYMERYRKRLKAKNLMYIKQILYLLERFVVMLGGNVNQNPSCQVVSQTGTELKSINDFLFQSQIDNINLFKVQRYCEKSLISRKLFGFVERYGNPAPVVKTNKENQKLAGLQNFLMTLQQGSYKEGPLQSPPVEADSDQLRAASPLMHIEGFLSALTNANEDGRVILNRQGTIGQSSLKFLLLNPAVHFAKVVKECRAVIIAGGTMQPVADFREQLLSYAGVDPARIVEFSCGHVIPPENILPIILCSGPSNQQLEFTYQTRDLPQMMDETGRILCNLCNVVPGGVVCFFPSYDYEKQVYAHWEKTGLLTRLATKKKIFQEPKKANQVEQVLAEYAKCIKRCSQAGGQMTGALLLSVVGGKMSEGINFSDDLGRCVIMVGMPYPNIKSPELQEKMTWLDKTMPRSASQAPSRVLIENLCMKAVNQSIGRAIRHQKDYASILLLDHRYARPAILNKLPQWIRERIQVKPAFGSAFAELRKFHRGKSD", "length": 910, "header": "tr|A0A8V0YLC1-1|A0A8V0YLC1_CHICK Isoform 1 of ATP-dependent DNA helicase DDX11 OS=Gallus gallus OX=9031 GN=DDX11 PE=3 SV=1 CANONICAL=A0A8V0YLC1-1" }, "locus": { "chromosome": "1", "start_pos": 59991656, "end_pos": 59970906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029127.1", "url": "https://www.ensembl.org/id/ENSGALT00010029127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016884.1", "url": "https://www.ensembl.org/id/ENSGALP00010016884.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LEZ3-1", "protein_name": "ATP-dependent DNA helicase DDX11", "gene_name": "Ddx11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEESQEMGGIHFPFPFPPYPIQKDFMAELYKVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKLQAEAGLLAPASGPTSSGRNSVLSSSSCQEPSDTLRPAGDPDWVTEFVQKKEERDLVERLREEQLRRRKREERLQEVCQDGRRRFAAKRSRQEEEETETLLRLSREMLAADTAPEQLGQLECGEEHLVLAEYESDEERRGSRADEGEDDLEEEHITKIYYCSRTHSQLAQFVREVQKSPFGKETRLVSLGSRQSLCVNEDVKSLGSVHLMNDRCVDMQRRKHKKMRIGEDKPKRRRQKMQASCPFYNHEQMELLRDEILLEVKDMEQLVALGKEAQACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLDKFVAVLGGNVKQNPSTQSLPQTGSELQSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECFGVVLPSLSDSEENRGLGGFQQFLKSLQSGPPEDSLEEGQAVALRPASPLMHIEAFLEALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRALVIAGGTMQPALRSQGLMSLLQVSDFREQLLACSGVEASRVVEFSCGHVIPPDNILPLIICSGPSNQQLEFTYQRRELPQMMEETGRILCNLCNVVPGGMVCFLPSYEYLRQVHAHWDKTGLLARLSVRKKIFQEPKRASQVEQVLTAYSTCIASCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLDQTIPRTHGQPPPGTVLIENLCMKAINQSIGRAIRHQKDFASIVLLDHRYARPSILAKLPAWIRDRVEVKATFGPAFAAMRKFHREKSHPCLGFVVNL", "length": 923 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R345-1", "protein_name": "ATP-dependent DNA helicase DDX11", "gene_name": "ddx11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESKSGRFPFPFQPYPIQESFMEALYTALDQRKVGIFESPTGTGKSLSLICGALTWLRDYEEQRKQEAARLLEGQKDSDVVKEKNSNSGPPEPDWVSEFVQKKAERDMVNKLKDEELKRKKREERLEMIRHNAQLRYAMKRKADEDDEAVKLLQLSREGAEPETHSPEEEGLIVAEYESDDEATPKSRLCDDDNDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYGDAVRLVNLGSRQNLCINPEVVRLGNVQMMNERCLEMQKNKHEKRQKASDSESKRSRGLAKATCVFSRFENLMAMKDEVLVKVRDVEQLIQHGRETHTCPYYSTRMSIPAAQVVVLPYQSLLHASTRKASGIKLKDQIVIIDEAHNLMDTISAIHSAEISGGQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGQNPNTQSCQTGSELLTINDFLFKAQVDNINLFKVQKYFEKSMISRKLCGFAEKYEGSGINTHSSSKNKENRRTEGLGRFLQTLQSKPTDVSEQQMAVEDKPIMASPMMLAESFLFALTNANKDGRVVIQRQACVAQSSLKFLLLNAAVHFAQILQECRAVIIAGGTMQPVADFKEQLLFSAGVTEERILEFSCGHVIPPENILPIVLCAGPSGQQLEFTFQTRDSPQMMEETGRVLSNLCNIVPGGVVCFFPSYEYEKRILGHWESTGILQRLQSKKKIFQEPKKASQVEQVLSEYSKCIQRCSNIGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVAGKSPGKALVESLCMKAVNQSIGRAIRHRGDYACIVLCDHRYARTGTLQKLPEWIRSSTHTHATFGPAFASARRFFLEKRQKATL", "length": 890 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P22516-1", "protein_name": "ATP-dependent DNA helicase CHL1", "gene_name": "CHL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDKKEYSETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSEDITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTTHQVISSTRKFFSMRSLNSR", "length": 861 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6AXC6-1", "protein_name": "ATP-dependent DNA helicase DDX11", "gene_name": "Ddx11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADENQEIGGIHFPFPFPPYPIQKDFMAELYKVLEGGKIGIFESPTGTGKSLSLICGALSWLRDFEKKKLQAEALLLAPGSGPPSSEKNSLLTSSSCQEPTDTPRPAGEPDWVTEFVQKKEERDLVERLREEQVRRRKREERLKEVCQDGRLRFAAKRTKHEEEETEALLRLSREMLDAGTGPEQLEQLECGEEHLVLAEYESDEERRGSRVDEAEDDLEEEHITKIYYCSRTHSQLAQFVREVLKSPFGKETRLVSLGSRQTLCVNEDVKNLGSVQLMNDRCVDMQRSKREKNGTGEDKPKRKRQKIQTSCPFYNHEQMELLRDEILLEVKDMEQLVALGKEARACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLEKFVAVLGGNVKQNPTTQSLSQTGSELKSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECFGVVLPSLSDSQENRGLAGFQQFLKSLQSGPTEDSPEEGQAVALRPASPLMHIEAFLAALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPMSDFREQLLACSGVEAGRVVEFSCGHVIPPDNILPLIICSGPSNQQLEFTYQRRELPQMVEETGRILCNLCNVVPGGVVCFLPSYEYLRQVHAHWDKTGLLTRLSVRKKIFQEPKRASQVEQVLMAYSKCIMSCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLNQTLPRTQGQPLPGTVLIENLCMKAINQSIGRAIRHQRDFASIVLLDHRYARPSILAKLPAWIRDRVEVKATFGPAFAAVRKFHREKSHPSLV", "length": 906 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FC9-1", "protein_name": "ATP-dependent DNA helicase DDX11", "gene_name": "DDX11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANETQKVGAIHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKREEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQLESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLSPRPGTPREGSGGEPVHEGRQPVHRQGHQAPEGFCQRSAPGPAICPAPCPGQAAGLDPSPCGGQSYLWPRHCCCAEVSPGEVGLFLMGNHTTAWRRALPLSCPLETVFVVGVVCGDPVTKVKPRRRVWSPECCQDPGTGVSSRRRKWGNPE", "length": 970 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CA92-1", "protein_name": "RAD3-like DNA-binding helicase protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTEIREFPAFPYKPYSIQIDFMNALYQFLDKGGVSMLESPTGTGKSLSIICSALQWLTDRKEKRNSGLTEESHKVDGNDDEDEPDWMRNFTLNEADGANGDKSIKNTKSPFSLRKHAKEVFTEGEKADELNDQEFLLDEYESQDESSPGGGNSKRKPARGFDSSSSEDEEDENDCSDDEQGGFKVFFCSRTHSQLSQFVKELRKTVFAKKLKVVCLGSRKNLCINEDVLKLGNVTRINERCLDLQKKKISQVSKKKNLGANVRIVRTKASCRCPMLRKHKLQREFKAESFQQEAMDIEDLVQLGREMRTCPYYGSRRMAPAADLVILPYQSLLSKSSRESLGLSLKNSVVIIDEAHNLADTLLSMHDAKLTVSQLEDIHCSIESYLGRFQNLLGAGNRRYIQIMLILTRAFLKPLASDRNLSSVNVGLDTENPSKSKPCGACSMAIYDFLFSLNIDNINLVKLLAYIKESNIIHKVSGYGERVAAMLQKDPVAHEEMSKLTSFRAFSDMLVALTNNNGDGRIIISRTSSSTSGQHGGYIKYVMLTGAKLFSEVVDEAHAVILAGGTLQPIEETRERLFPWLPSNQLQFFSCSHIVPPESIMPIAVSHGPSGQSFDFSHSSRSSIGMIQELGLLMSNLVAVVPEGIIVFFSSFEYETQVHTAWSNSGILRRIVKKKRVFREPRKNTEVEAVLRDYKEAIESERGAIMLAVVGGKVSEGINFSDSMCRCVVMVGLPYPSPSDIELLERIKHIEGRADSDSIKPSVTLVDDSYYSGDVQAGFGVLKSCKRRGKEYYENLCMKAVNQSIGRAIRHEKDYASILLVDARYSNDPSKRTSHSHPSNKLPKWIKDRLIYSTKGYGDVHRLLHQFFKHKNVENSSETNQH", "length": 882 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9XZS9-1", "protein_name": "DNA 5'-3' helicase", "gene_name": "cg11403", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQYTPNQRLDTPGAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIRGVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGRVHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSNAEDGRILVDPVGGTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKEQLFTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAEQLLDNYALAIKRPASYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEANAANGGFGAVQGRTARFFKGR", "length": 861 }, "evidence": [ { "id": "A0A8V0YLC1", "url": "https://omabrowser.org/oma/group/A0A8V0YLC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 17, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "triplex DNA binding", "id": "GO:0045142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045142", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" 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"https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "id": "GO:1901838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "cellular response to bleomycin", "id": "GO:1904976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "nucleolar chromatin organization", "id": "GO:1990700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair", "id": "GO:2000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" }, { "name": "establishment of sister chromatid cohesion", "id": "GO:0034085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", 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{ "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": 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"gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ] }, { "uniprot_ac": "A0A8V0ZC95", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] } ] }, { "uniprot_ac": "A0A8V0ZE45", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZNU6", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZNU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZNU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZNW3", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS56" } ] } ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] } ] }, { "uniprot_ac": "A0A8V0ZUQ0", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": 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"activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 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"A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] } ] }, { "uniprot_ac": "A0A8V1AFG8", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643097" }, "gene_names": [ { "name": "TRABD2A", "type": "recommended", "evidence": [ { "id": "A0A8V0YH73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ] }, { "name": "TRABD2A", "type": "synonym", "evidence": [ { "id": "XP_003643097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643097" } ] } ], "protein_names": [ { "name": "Metalloprotease TIKI", "type": "recommended", "evidence": [ { "id": "A0A8V0YH73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73/entry#names_and_taxonomy" } ] }, { "name": "3.4.-.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YH73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73/entry#names_and_taxonomy" } ] }, { "name": "TRAB domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YH73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73/entry#names_and_taxonomy" } ] }, { "name": "metalloprotease TIKI1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643097" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643097.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643097" } ] }, { "annotation": "Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y8U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U9#function" }, { "database": "UniProtKB", "id": "RU369069", "url": "https://www.uniprot.org/uniprotkb/RU369069#function" }, { "database": "UniProtKB", "id": "A0A8V0YH68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH68#function" }, { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRABD2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73", "locus": { "chromosome": "Z", "start_pos": 53591599, "end_pos": 53676642, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012308", "url": "https://www.ensembl.org/id/ENSGALG00010012308" } ] } } ], "crossref": [ { "id": "A0A8V0YH73", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH73", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14789", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14789", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427288", "url": "https://www.ncbi.nlm.nih.gov/gene/427288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427288", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHHDLER", "url": "https://omabrowser.org/oma/group/HHHDLER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8U9", "url": "https://www.orthodb.org/?gene=A0A8V0Y8U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH68", "url": "https://www.orthodb.org/?gene=A0A8V0YH68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH73", "url": "https://www.orthodb.org/?gene=A0A8V0YH73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31120:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31120:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHPGWVCLLQSLLLLARARQSRGPAGACPLRGKSELNSFLWTIKRDPPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHVVYFELDLTDPYTISALTSCQLLPQGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPDQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLNGLNFSQVIFALNQTLLQQESLRAGSFQIPYTTEDLIKHYNCGDLSSIIFNHDTSQVPNFINATLPAHERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEYPNRSFFFAFGAGHFMGNNTVIDVLRREGYDVEHTPAGQAINNGKLPKTLLAFSSSSPVHHPYVVSQELPVPLHTLKEEEEELLPHLLLPDGIDVLEKVERKYKKKKKQQKKQRLRQFNDLWVRFEESATDPPPRIRIINGYITVEPQPRGHGRFSPARTDTSGSHQLSHSLLLSLLTSAMHLMRLH", "length": 502, "header": "tr|A0A8V0YH73-1|A0A8V0YH73_CHICK Isoform 1 of Metalloprotease TIKI OS=Gallus gallus OX=9031 GN=TRABD2A PE=3 SV=1 CANONICAL=A0A8V0YH73-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U9/entry", "sequence": { "sequence": "MVHPGWVCLLQSLLLLARARQSRGPAGACPLRGKSELNSFLWTIKRDPPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHVVYFELDLTDPYTISALTSCQLLPQGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPDQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLNGLNFSQVIFALNQTLLQQESLRAGSFQIPYTTEDLIKHYNCGDLSSIIFNHDTSQVPNFINATLPAHERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEYPNRSFFFAFGAVPPTLLPVSVSSMATSRWNPSPGAMDDSVPLAQTPAALTSSPTPSCSHY", "length": 376, "header": "tr|A0A8V0Y8U9-1|A0A8V0YH73_CHICK Computationally mapped isoform of Metalloprotease TIKI OS=Gallus gallus OX=9031 GN=TRABD2A PE=3 SV=1 CANONICAL=A0A8V0YH73-1" }, "locus": { "chromosome": "Z", "start_pos": 53676358, "end_pos": 53592345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029469.1", "url": "https://www.ensembl.org/id/ENSGALT00010029469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017126.1", "url": "https://www.ensembl.org/id/ENSGALP00010017126.1" } ] } }, { "isoform_ac": "A0A8V0YH68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH68/entry", "sequence": { "sequence": "MKARRPGIDCCLCCGDACKSELNSFLWTIKRDPPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHVVYFELDLTDPYTISALTSCQLLPQGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPDQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLNGLNFSQVIFALNQTLLQQESLRAGSFQIPYTTEDLIKHYNCGDLSSIIFNHDTSQVPNFINATLPAHERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEYPNRSFFFAFGAGHFMGNNTVIDVLRREGYDVEHTPAGQAINNGKLPKTLLAFSSSSPVHHPYVVSQELPVPLHTLKEEEEELLPHLLLPDGIDVLEKVERKYKKKKKQQKKQRLRQFNDLWVRFEESATDPPPRIRIINGYITVEPQPRGHGRFSPARTDTSGSHQLSHSLLLSLLTSAMHLMRLH", "length": 487, "header": "tr|A0A8V0YH68-1|A0A8V0YH68_CHICK Computationally mapped isoform of Metalloprotease TIKI OS=Gallus gallus OX=9031 GN=TRABD2A PE=3 SV=1 CANONICAL=A0A8V0YH73-1" }, "locus": { "chromosome": "Z", "start_pos": 53670844, "end_pos": 53592313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029459.1", "url": "https://www.ensembl.org/id/ENSGALT00010029459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017119.1", "url": "https://www.ensembl.org/id/ENSGALP00010017119.1" } ] } }, { "isoform_ac": "A0A8V0YH73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73/entry", "sequence": { "sequence": "MVHPGWVCLLQSLLLLARARQSRGPAGACPLRGKSELNSFLWTIKRDPPSYFFGTIHVPYTRVWDFIPENSKKAFQQSHVVYFELDLTDPYTISALTSCQLLPQGENLQDVLPRDIYRRLKRHLEYVKLMMPSWMTPDQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTEVDIKSRGVPVLDLYLAQEAERLRKQTGAVEKVEEQCHPLNGLNFSQVIFALNQTLLQQESLRAGSFQIPYTTEDLIKHYNCGDLSSIIFNHDTSQVPNFINATLPAHERITAQEIDSYFRQELIYKRNERMGRRVKDLLEEYPNRSFFFAFGAGHFMGNNTVIDVLRREGYDVEHTPAGQAINNGKLPKTLLAFSSSSPVHHPYVVSQELPVPLHTLKEEEEELLPHLLLPDGIDVLEKVERKYKKKKKQQKKQRLRQFNDLWVRFEESATDPPPRIRIINGYITVEPQPRGHGRFSPARTDTSGSHQLSHSLLLSLLTSAMHLMRLH", "length": 502, "header": "tr|A0A8V0YH73-1|A0A8V0YH73_CHICK Isoform 1 of Metalloprotease TIKI OS=Gallus gallus OX=9031 GN=TRABD2A PE=3 SV=1 CANONICAL=A0A8V0YH73-1" }, "locus": { "chromosome": "Z", "start_pos": 53676358, "end_pos": 53592313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029466.1", "url": "https://www.ensembl.org/id/ENSGALT00010029466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017124.1", "url": "https://www.ensembl.org/id/ENSGALP00010017124.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427288", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F6V0-1", "protein_name": "Metalloprotease TIKI1", "gene_name": "trabd2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTMMTMMMVSWSAFLQICWILMVRANQFNPGEPSGCRTNTPQSDLNSFLWTIKRDPPSYLYGTIHVPYTRVWDFIPQNSKQAFQESSVVYFELELTDPSTISALSRCQLLPAGQNLQDVLPPELYLRLKTHLEYVRLMLPSWMTPDQRGKGLYAEYLFNAIAGNWERKRPVWVMLMVNSLTEADIKTRGVPVLDLYLAQEAERMKKQTGAVEKVEEQCSPLNTLDFSQVIFALNQTLLQQESVRAGSLQVPYTTEHLITHYNCGDLHSIISHDTAQVPNFNNVTLRPSDQVTAQQIDSYFRRELIYKRNERMGRRVTALLQEQPHKTFFFAFGAGHFLGNNSVIDVLRREGYEVEHTPAGQPLHRRSGWRSADPADTDAALQPFLHHSRHHELQLLEGLELLEKVEHKLKKKHRRNKLKKQRQFNDLWVRMEDSVTAEAPPPLIHIINGYITVQTHPQEHERANHDRTFSGSSSRTGPALSALAVCVQMLRLLL", "length": 494 }, "evidence": [ { "id": "A0A8V0YH73", "url": "https://omabrowser.org/oma/group/A0A8V0YH73/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YF83-1", "uniprot_ac": "A0A8V0YF83", "uniprot_id": "A0A8V0YF83_CHICK", "mass": { "chemical_mass": 302615.0, "monoisotopic_mass": 302615.0 }, "refseq": {}, "gene_names": [ { "name": "WNK1", "type": "recommended", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WNK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83", "locus": { "chromosome": "1", "start_pos": 60589717, "end_pos": 60491607, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012339", "url": "https://www.ensembl.org/id/ENSGALG00010012339" } ] } } ], "crossref": [ { "id": "cd14030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y906", "url": "https://www.orthodb.org/?gene=A0A8V0Y906", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE18", "url": "https://www.orthodb.org/?gene=A0A8V0YE18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE30", "url": "https://www.orthodb.org/?gene=A0A8V0YE30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF83", "url": "https://www.orthodb.org/?gene=A0A8V0YF83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM64", "url": "https://www.orthodb.org/?gene=A0A8V0YM64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y906", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y906", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y906-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y906-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVPQRGRSMSVCVPHLPALPYMSCIPLSAPCTPPPALSAPLSPFYLRTVPEETFAEKLSKALESVLPMHSASPRKHRRSSLPSLSVSPPQHPRGGTPTFPDSQIFFPTVHERPVSFSPPPVCPPKVAVAQRRKSTSFLEAQTCHFQPLLKTGQSLVPPGGSPTNWTPEALVMLGTTSHRVAGEPLHVQVNPVFEPAPVHSDYRSGPTPPEDAHYRMHPEAVYLVGMHYPSQVSEQYDQVAYNSHVTEQHLKQVSESKHVQGGPPQSSVFDYQSGQAFLARHVQNLRLDAGLSPLSPLSSVSAPLSADPAQMTFHQVFVPHSAPAVLSHSGDGRTSCVFEFHVHTPSSAPAEGVALPQRVYRSRRGSMETSQEESTQGIGLHGRLQPVTEEHYNYLGPDLAGPRGGSASRSWPEGSPEYSSDSSQLTSSDTGDFQSPPPTGGPSAFGSDFSLPIVQLPQKVLQESQLFICFPQGASTQQALSTSLSSGPPAHYPQTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQLPVSQPVSIIQGEPQLPVAAPSLPQPSVAPSVPIGSHFLPVGQPLPTSIVPQFSVSQLPVAAPHVSVAQPGFQSLPISMAGSMNQPLLTLATSAAATAVPVGSTVVPSQLPTLMQPVAQLPSQVLPQLLQPAVQSMGLPVSIGQAADASLPAGDALYQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPVLPVGSELPAGTPSSEPLPPFPGPSLTQSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2880, "header": "tr|A0A8V0YF83-1|A0A8V0YF83_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y906-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y906/entry", "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVPQHPRGGTPTFPDSQIFFPTVHERPVSFSPPPVCPPKVAVAQRRKSTSFLEAQTCHFQPLLKTGQSLVPPGGSPTNWTPEALVMLGTTSHRVAGEPLHVQVNPVFEPAPVHSDYRSGPTPPEDAHYRMHPEAVYLVGMHYPSQVSEQYDQVAYNSHVTEQHLKQVSESKHVQGGPPQSSVFDYQSGQAFLARHVQNLRLDAGLSPLSPLSSVSAPLSADPAQMTFHQVFVPHSAPAVLSHSGDGRTSCVFEFHVHTPSSAPAEGVALPQRVYRSRRGSMETSQEESTQGIGLHGRLQPVTEEHYNYLGPDLAGPRGGSASRSWPEGSPEYSSDSSQLTSSDTGDFQSPPPTGGPSAFGSDFSLPIVQLPQKVLQESQLFICFPQGASTQQALSTSLSSGPPAHYPQTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQLPVSQPVSIIQGEPQLPVAAPSLPQPSVAPSVPIGSHFLPVGQPLPTSIVPQFSVSQLPVAAPHVSVAQPGFQSLPISMAGSMNQPLLTLATSAAATAVPVGSTVVPSQLPTLMQPVAQLPSQVLPQLLQPAVQSMGLPVSIGQAADASLPAGDALYQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPVLPVGSELPAGTPSSEPLPPFPGPSLTQSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2794, "header": "tr|A0A8V0Y906-1|A0A8V0YF83_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "locus": { "chromosome": "1", "start_pos": 60588903, "end_pos": 60491806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029556.1", "url": "https://www.ensembl.org/id/ENSGALT00010029556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017183.1", "url": "https://www.ensembl.org/id/ENSGALP00010017183.1" } ] } }, { "isoform_ac": "A0A8V0YE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE18/entry", "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVPQRGRSMSVCVPHLPALPYMSCIPLSAPCTPPPALSAPLSPFYLRTVPEETFAEKLSKALESVLPMHSASPRKHRRSSLPSLSVSPPQHPRGGTPTFPDSQIFFPTVHERPVSFSPPPVCPPKVAVAQRRKSTSFLEAQTCHFQPLLKTGQSLVPPGGSPTNWTPEALVMLGTTSHRVAGEPLHVQVNPVFEPAPVHSDYRSGPTPPEDAHYRMHPEAVYLVGMHYPSQVSEQYDQVAYNSHVTEQHLKQVSESKHVQGGPPQSSVFDYQSGQAFLARHVQNLRLDAGLSPLSPLSSVSAPLSADPAQMTFHQVFVPHSAPAVLSHSGDGRTSCVFEFHVHTPSSAPAEGVALPQRVYRSRRGSMETSQEESTQGIGLHGRLQPVTEEHYNYLGPDLAGPRGGSASRSWPEGSPEYSSDSSQLTSSDTGDFQSPPPTGGPSAFGSDFSLPIVQLPQKVLQESQLFICFPQGASTQQALSTSLSSGPPAHYPQTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPVLPVGSELPAGTPSSEPLPPFPGPSLTQSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2722, "header": "tr|A0A8V0YE18-1|A0A8V0YF83_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "locus": { "chromosome": "1", "start_pos": 60588903, "end_pos": 60491806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029550.1", "url": "https://www.ensembl.org/id/ENSGALT00010029550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017177.1", "url": "https://www.ensembl.org/id/ENSGALP00010017177.1" } ] } }, { "isoform_ac": "A0A8V0YE30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE30/entry", "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQLPVSQPVSIIQGEPQLPVAAPSLPQPSVAPSVPIGSHFLPVGQPLPTSIVPQFSVSQLPVAAPHVSVAQPGFQSLPISMAGSMNQPLLTLATSAAATAVPVGSTVVPSQLPTLMQPVAQLPSQVLPQLLQPAVQSMGLPVSIGQAADASLPAGDALYQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEQNVMPMWGPCCHWLFCWEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPVLPVGSELPAGTPSSEPLPPFPGPSLTQSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2406, "header": "tr|A0A8V0YE30-1|A0A8V0YF83_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "locus": { "chromosome": "1", "start_pos": 60588903, "end_pos": 60491806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029560.1", "url": "https://www.ensembl.org/id/ENSGALT00010029560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017187.1", "url": "https://www.ensembl.org/id/ENSGALP00010017187.1" } ] } }, { "isoform_ac": "A0A8V0YF83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83/entry", "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVPQRGRSMSVCVPHLPALPYMSCIPLSAPCTPPPALSAPLSPFYLRTVPEETFAEKLSKALESVLPMHSASPRKHRRSSLPSLSVSPPQHPRGGTPTFPDSQIFFPTVHERPVSFSPPPVCPPKVAVAQRRKSTSFLEAQTCHFQPLLKTGQSLVPPGGSPTNWTPEALVMLGTTSHRVAGEPLHVQVNPVFEPAPVHSDYRSGPTPPEDAHYRMHPEAVYLVGMHYPSQVSEQYDQVAYNSHVTEQHLKQVSESKHVQGGPPQSSVFDYQSGQAFLARHVQNLRLDAGLSPLSPLSSVSAPLSADPAQMTFHQVFVPHSAPAVLSHSGDGRTSCVFEFHVHTPSSAPAEGVALPQRVYRSRRGSMETSQEESTQGIGLHGRLQPVTEEHYNYLGPDLAGPRGGSASRSWPEGSPEYSSDSSQLTSSDTGDFQSPPPTGGPSAFGSDFSLPIVQLPQKVLQESQLFICFPQGASTQQALSTSLSSGPPAHYPQTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQLPVSQPVSIIQGEPQLPVAAPSLPQPSVAPSVPIGSHFLPVGQPLPTSIVPQFSVSQLPVAAPHVSVAQPGFQSLPISMAGSMNQPLLTLATSAAATAVPVGSTVVPSQLPTLMQPVAQLPSQVLPQLLQPAVQSMGLPVSIGQAADASLPAGDALYQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPVLPVGSELPAGTPSSEPLPPFPGPSLTQSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2880, "header": "tr|A0A8V0YF83-1|A0A8V0YF83_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "locus": { "chromosome": "1", "start_pos": 60588903, "end_pos": 60491806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029543.1", "url": "https://www.ensembl.org/id/ENSGALT00010029543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017174.1", "url": "https://www.ensembl.org/id/ENSGALP00010017174.1" } ] } }, { "isoform_ac": "A0A8V0YM64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM64/entry", "sequence": { "sequence": "MSGGAADGAPPAPRFLAPPPPPPKNGSSSDSSVGEKLGAAEHAASGTGGASGGAGSGGRSEEYRRRRHTMDKDSRGAAATEHRFFRRSVICDSNATALELPSLQPAAPSAPVSGGSAAPLVSPPECVRTSCIAVGASQAPSLLQQPPPPAPLPLEGRSAQEPPATKDAAPLLPKEEEDEAAALPPTSAAGSTVTASREFEERRAQQEDIEELETKAVGISPDGRFLKFDIEIGRGSFKTVYKGLDTDTTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKGERYAIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKLQEEGSQKQQLEQQQPSSASHAGSKHPVSVSGTTPVPTTSASVSTQVEPEEPEADQHQQLQFQQPSISILSDGAVDSGQGSSVYTESCVSSQQTVSYGSQHDQPISTAAVQGYAASVGQVQSQQHGGYQPPAVTQVQGQSASSSTSVPSQPTQHTQQNAQQPASSQQPGQYQLQQPSVSTGATPTQTVSQTQTSQVMPMPQAAAGTQLPVSQPVSIIQGEPQLPVAAPSLPQPSVAPSVPIGSHFLPVGQPLPTSIVPQFSVSQLPVAAPHVSVAQPGFQSLPISMAGSMNQPLLTLATSAAATAVPVGSTVVPSQLPTLMQPVAQLPSQVLPQLLQPAVQSMGLPVSIGQAADASLPAGDALYQGFPSRLPPQYPGDSSVAPSSAVASVSIPSAILSPPLPTDVMTQPGYIAPVVQPYVEQSVLVPMGNVGGQVQVPQPTVSLTQQASSASSQQAVVEGTQGASQTAPSESLPSTQPAQSTPLASSMDSAHSDVASGMSDGNENVPASSGRHEGRTTKRHMRRSVRSRSRHEKTARPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIASIMVQNEFILATERDSFVEQVREIIEKADEMLSEDVSVEPEGDQGLESMQTKDDGFIPGSQKLEFKQPDPTSSMPQRIGVPPSSFTQVVHSAGRRFIVSPVPESRLKEQGFFTSPIPGGKETSDVVAASPLHGPGMNLSHSASSLSLQQAFSEIGHGQMTEGPSTAPPVFNQTIPPFPPALSTMASSGAPPASVAAPSISIPSSTGVSLPSSVTLSSENAAVGVAPSASVPSSVSPPLASQSGQQLSGGVASSVSAPASFSLTITSQPAQPVTGDIAPSISTPASLALPATQVPGVTGLGVVAPAVTSQSTPQIVSSLAAPQTSVALSQAQNVALQLPQLTSSGSVSSLAETTVVSAPQSLPESGQSADKSQPSSAAGLSLPISAPLSSSVATSLCGSVTQPVIHPLLIPSAITSTPVLSQIPGATPVLPQVPLPGVLPQPVTNLPAVQQTLIHSQPQPAPLPNQPHIHCLEADADAQSKAPGIDDIKTLEEKLRSLFSEHGNVGAAHPSVSLETSLIMETTVIPGIPTTVVAPTKPLTSVSTCIPPSSLPLGPAGLPVLTPVATPGQVITPVSYISAPSSVATAVVKPGTSPSKPPLSRVPSQQPLEDLDAKLRRTLSPETVPVTSAPACSVPSVASTAVTGLVSTAAQSLKDASASCGGESSGTASTTGAGVLKMGRFQVSVAVDDVLKESDKAETKPLQFETTSSDSSPLSGSSPESTLVKQAGGRKSEAVAHGSPQPVPVLQLPVDDGQPTKVGRFQVTTTTDQVGRFSVSKTQDEVTCAEREPMTLPLSVDLEQVASSAAAPRKELESRQSPHMNGPSSEPEAAFLSGMAKDLDDGSASPDSLQATASKISLPVQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQELQSRQKQEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKGKSSKSSRSSSQGNKSPQLSGNLSAQSAPSVLPPQQTLHPPGSVPETGQNHLLQPLKPSPSSENLYSAFTSDGALSVPSLSAPGQGTSSTNAVGATVNSQAPQSQPTAIASSRKGTFTDDLHKLVDNWARDAMNLSGKKVGKGHSNYEGPGMARKFSAPGQLCISMTSSLGATPISAASATSLGPFTKAMCPPQQYGYPAASFAAPWSGTSGPAQQPLSQFQPVGATSLQSFNISGLQKSISNPPGSNLRTT", "length": 2360, "header": "tr|A0A8V0YM64-1|A0A8V0YM64_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=WNK1 PE=1 SV=1 CANONICAL=A0A8V0YF83-1" }, "locus": { "chromosome": "1", "start_pos": 60588903, "end_pos": 60491806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029562.1", "url": "https://www.ensembl.org/id/ENSGALT00010029562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017189.1", "url": "https://www.ensembl.org/id/ENSGALP00010017189.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1520, "start_aa": "Thr", "end_pos": 1520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1520", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2224, "start_aa": "Thr", "end_pos": 2224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2224", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 441, "start_aa": "Thr", "end_pos": 441, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr441", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 925, "start_aa": "Thr", "end_pos": 925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr925", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "potassium channel inhibitor activity", "id": "GO:0019870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 28, "go_terms": [ { "name": "intracellular chloride ion homeostasis", "id": "GO:0030644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030644", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "negative regulation of cell-cell adhesion mediated by integrin", "id": "GO:0033633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "positive regulation of T cell chemotaxis", "id": "GO:0010820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "negative regulation of heterotypic cell-cell adhesion", "id": "GO:0034115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "regulation of mRNA export from nucleus", "id": "GO:0010793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "negative regulation of leukocyte cell-cell adhesion", "id": "GO:1903038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF83", "url": 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"uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"chemical_mass": 139451.0, "monoisotopic_mass": 139451.0 }, "refseq": { "ac": "NP_989748", "name": "receptor-type tyrosine-protein phosphatase C precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" }, "gene_names": [ { "name": "PTPRC", "type": "recommended", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "name": "PTPRC", "type": "synonym", "evidence": [ { "id": "NP_989748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" } ] } ], "protein_names": [ { "name": "Receptor-type tyrosine-protein phosphatase C", "type": "recommended", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8/entry#names_and_taxonomy" } ] }, { "name": "Leukocyte common antigen", "type": "synonym", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8/entry#names_and_taxonomy" } ] }, { "name": "leukocyte common antigen, CD45", "type": "synonym", "evidence": [ { "id": "NP_989748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" } ] }, { "name": "receptor-type tyrosine-protein phosphatase C precursor", "type": "synonym", "evidence": [ { "id": "NP_989748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" } ] }, { "name": "receptor-type tyrosine-protein phosphatase C", "type": "synonym", "evidence": [ { "id": "NP_989748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: L13285.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Sep 23, 2021 this sequence version replaced NP_989748.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989748", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPRC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8", "locus": { "chromosome": "8", "start_pos": 2035004, "end_pos": 2093100, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012352", "url": "https://www.ensembl.org/id/ENSGALG00010012352" } ] } } ], "crossref": [ { "id": "A0A8V0YFC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "386580", "url": "https://www.ncbi.nlm.nih.gov/gene/386580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:386580", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHGYWGP", "url": "https://omabrowser.org/oma/group/IHGYWGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y922", "url": "https://www.orthodb.org/?gene=A0A8V0Y922", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y930", "url": "https://www.orthodb.org/?gene=A0A8V0Y930", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y943", "url": "https://www.orthodb.org/?gene=A0A8V0Y943", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFA6", "url": "https://www.orthodb.org/?gene=A0A8V0YFA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFC8", "url": "https://www.orthodb.org/?gene=A0A8V0YFC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHF2", "url": "https://www.orthodb.org/?gene=A0A8V0YHF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHG4", "url": "https://www.orthodb.org/?gene=A0A8V0YHG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM93", "url": "https://www.orthodb.org/?gene=A0A8V0YM93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134:SF539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134:SF539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416700", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989748", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y922", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y922", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y922-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y922-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y930", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y930-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y930-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y943", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y943", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y943-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y943-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQAGNDNLTSASSLSSTLPTPTRSTSFSPPSTTAGVQPASTGASPTASTHLSTHSGSGPTTGLGHLQHSSPAALTTRTLTAFHQTVSDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1237, "header": "tr|A0A8V0YFC8-1|A0A8V0YFC8_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y922-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y922/entry", "sequence": { "sequence": "MSFSPSCISHLMISFSHCAAGNDNLTSASSLSSTLPTPTRSTSFSPPSTTAGVQPASTESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1159, "header": "tr|A0A8V0Y922-1|A0A8V0YFC8_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2063187, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029577.1", "url": "https://www.ensembl.org/id/ENSGALT00010029577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017200.1", "url": "https://www.ensembl.org/id/ENSGALP00010017200.1" } ] } }, { "isoform_ac": "A0A8V0Y930-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y930/entry", "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1152, "header": "tr|A0A8V0Y930-1|A0A8V0YFC8_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2092915, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029589.1", "url": "https://www.ensembl.org/id/ENSGALT00010029589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017210.1", "url": "https://www.ensembl.org/id/ENSGALP00010017210.1" } ] } }, { "isoform_ac": "A0A8V0Y943-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y943/entry", "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQAGNDNLTSASSLSSTLPTPTRSTSFSPPSTTAAFDAVPLTTGASPTASTHLSTHSGSGPTTGLGHLQHSSPAALTTRTLTAFHQTVSDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLRQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1223, "header": "tr|A0A8V0Y943-1|A0A8V0YFC8_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2092915, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029609.1", "url": "https://www.ensembl.org/id/ENSGALT00010029609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017225.1", "url": "https://www.ensembl.org/id/ENSGALP00010017225.1" } ] } }, { "isoform_ac": "A0A8V0YFA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFA6/entry", "sequence": { "sequence": "MSFSPSCISHLMISFSHCAAGNDNLTSASSLSSTLPTPTRSTSFSPPSTTAGVQPASTGASPTASTHLSTHSGSGPTTGLGHLQHSSPAALTTRTLTAFHQTVSDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1234, "header": "tr|A0A8V0YFA6-1|A0A8V0YFA6_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2063187, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029573.1", "url": "https://www.ensembl.org/id/ENSGALT00010029573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017197.1", "url": "https://www.ensembl.org/id/ENSGALP00010017197.1" } ] } }, { "isoform_ac": "A0A8V0YFC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8/entry", "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQAGNDNLTSASSLSSTLPTPTRSTSFSPPSTTAGVQPASTGASPTASTHLSTHSGSGPTTGLGHLQHSSPAALTTRTLTAFHQTVSDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1237, "header": "tr|A0A8V0YFC8-1|A0A8V0YFC8_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2092915, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029596.1", "url": "https://www.ensembl.org/id/ENSGALT00010029596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017217.1", "url": "https://www.ensembl.org/id/ENSGALP00010017217.1" } ] } }, { "isoform_ac": "A0A8V0YHF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF2/entry", "sequence": { "sequence": "MPLCCKSGVQPASTESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1115, "header": "tr|A0A8V0YHF2-1|A0A8V0YHF2_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2082427, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029580.1", "url": "https://www.ensembl.org/id/ENSGALT00010029580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017203.1", "url": "https://www.ensembl.org/id/ENSGALP00010017203.1" } ] } }, { "isoform_ac": "A0A8V0YHG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG4/entry", "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQVQPASTDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1158, "header": "tr|A0A8V0YHG4-1|A0A8V0YHG4_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2092915, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029592.1", "url": "https://www.ensembl.org/id/ENSGALT00010029592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017213.1", "url": "https://www.ensembl.org/id/ENSGALP00010017213.1" } ] } }, { "isoform_ac": "A0A8V0YM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM93/entry", "sequence": { "sequence": "MFLCLKLLAFGVAFLCQDAFAQGVQPASTGASPTASTHLSTHSGSGPTTGLGHLQHSSPAALTTRTLTAFHQTVSDYYSSTSLHNTTSPVITPASTETIPTSTIESTTTTEEPCDNSIDYGNIEEKNNSAEVTLKNLKENRIYDILLEDGKSLSVNASNNIVMLNWCRRYTVQSRNCIVMYLTIPPDEKRYTFDVESIGNDNATLRLNPLCIDCEDVCSNVTVSCKTNSINSGGTGNLTGSYELMKHDINADNITILSLSSDSEYLCRVTVRFFEKNFTKEVNITTDYDAPKAPENLTVHPTARNVTVTWMKPTGTLEEHIDGYIVKCNNTSQNVNRNETSFTCGDLEPYSTGSVSVRAFKKSKYKNKNFEGEKVNGSFQTKPAKPEKVTDFKLTLLADNTVKVACRSQKVYGNETKFKLSWNSSSNSGENQRKNECNFTVRDLSYLTKYTFKISVFNGVYTGDSVCEEIYTRYNSRALIIFLVFLIVVTSIALLLVLYKIYDLHQKKLSNSSEVISLVAVKDDERQLLNIEPIPSEKLLETYKRKIADEGRLFLDEFQSIPRIFTKFPMKEAKRSHNQNKNRYIDILPYDHNRVELSEIPGDPGSDYINASYIDGFKEPRKYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEGNRNKCAQYWPSMENGSATYGDITVKINESKICPDYIIQKLHITNGRERTSGRDVTHIQFTSWPDHGVPEDPHLLLKLRRRVNALSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLDAEGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYNQYGETEVSLSELHSYLNNLKRKDPPSEPSLLEAEFQRLPSYKGWRTQNTGNREENKNKNRSANTIPYDFNRVPIRSEEEQSKEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPKAMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEGDQELCAQYWGEGRQTYDDIEVQVTDVNCCPSYTIRAFDVTHLKRKETQKVYQYQYHKWNGLDVPEDPKDLVDMILSLKQKVPSRPASEDSRNSRSVPFVIHCCDGSQQTGVFCALMTLLESAETEEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYPAQNGQIKNIHQEDKVEFCNEVEKKDQESDLITIDLTPSTPEENDTPECCDDFKAADTNKGTESSTNGPTTPVLT", "length": 1205, "header": "tr|A0A8V0YM93-1|A0A8V0YM93_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase C OS=Gallus gallus OX=9031 GN=PTPRC PE=1 SV=1 CANONICAL=A0A8V0YFC8-1" }, "locus": { "chromosome": "8", "start_pos": 2092915, "end_pos": 2036108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029595.1", "url": "https://www.ensembl.org/id/ENSGALT00010029595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017216.1", "url": "https://www.ensembl.org/id/ENSGALP00010017216.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:386580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386580", "resource": "KEGG Pathway" }, { "id": "R-GGA-416700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416700", "resource": "Reactome", "description": "Other semaphorin interactions" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "bleb", "id": "GO:0032059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 34, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of antigen receptor-mediated signaling pathway", "id": "GO:0050857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of stem cell proliferation", "id": "GO:2000648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000648", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of B cell proliferation", "id": "GO:0030890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of T cell proliferation", "id": "GO:0042102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "positive regulation of interleukin-2 production", "id": "GO:0032743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of T cell mediated cytotoxicity", "id": "GO:0001915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "negative regulation of interleukin-4-mediated signaling pathway", "id": "GO:1902215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902215", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "bone marrow development", "id": "GO:0048539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "regulation of T cell receptor signaling pathway", "id": "GO:0050856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "cell cycle phase transition", "id": "GO:0044770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "regulation of interleukin-8 production", "id": "GO:0032677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "plasma membrane raft distribution", "id": "GO:0044855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044855", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" 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protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan binding", "id": "GO:0043395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "ankyrin binding", "id": "GO:0030506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ], "pmid": "" }, { "name": "protein tyrosine 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"A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-GGA-373746", "name": "SEMA4D interacts with CD45", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFC8-1" ], "evidence": [ { "id": "R-GGA-373746", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373746" } ] }, { "id": "R-GGA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X882", "gene_name": "MME", "activity": [ { "ec_number": "3.4.24.11", "activity": "Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1'.", "evidence": [ { "id": "A0A8V0X882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X882" } ] }, { "ec_number": "3.4.24.11", "activity": "", "evidence": [ { "id": "A0A8V0X882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X882" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y298", "gene_name": "B4GALT1", "activity": [ { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] }, { "ec_number": "2.4.1.90", "activity": "", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z0I1", "gene_name": "ANPEP", "activity": [ { "ec_number": "3.4.11.-", "activity": "", "evidence": [ { "id": "A0A8V0Z0I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0I1" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8U4", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U4" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144629.1. 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"id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL6A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1", "locus": { "chromosome": "7", "start_pos": 4933213, "end_pos": 4879953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012362", "url": "https://www.ensembl.org/id/ENSGALG00010012362" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22629", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22629", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396548", "url": "https://www.ncbi.nlm.nih.gov/gene/396548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396548", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396548", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSPDQMC", "url": "https://omabrowser.org/oma/group/CSPDQMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y950", "url": "https://www.orthodb.org/?gene=A0A8V0Y950", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y970", "url": "https://www.orthodb.org/?gene=A0A8V0Y970", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ9", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMB7", "url": "https://www.orthodb.org/?gene=A0A8V0YMB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015144629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y950", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y950", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y950-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y950-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y970", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y970", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y970-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y970-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAVRNVAVADIIFLVDSSWSIGKEHFQLVREFLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGKGLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDAVEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSADPFLQVSNDLARAGVLTFAVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTYVSGGVEEVPLAPTESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASADLRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMGDDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCPCCYGPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENDLADPCLLDFDMGMQCKDYQVVWFFDYKHKICSQGWYGGCGGNANRFETEAECNSKCLKPSAAEKAMQQPPLEKRLSPVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3215, "header": "tr|A0A8V0YHJ1-1|A0A8V0YHJ1_CHICK Isoform 1 of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y950-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y950/entry", "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSADPFLQVSNDLARAGVLTFAVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTYVSGGVEEVPLAPTESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASADLRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMGDDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCPCCYGPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENDLADPCLLDFDMGMQCKDYQVVWFFDYKHKICSQGWYGGCGGNANRFETEAECNSKCLKPSAAEKAMQQPPLEKRLSPVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3009, "header": "tr|A0A8V0Y950-1|A0A8V0YHJ1_CHICK Computationally mapped isoform of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "locus": { "chromosome": "7", "start_pos": 4932339, "end_pos": 4885850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029621.1", "url": "https://www.ensembl.org/id/ENSGALT00010029621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017235.1", "url": "https://www.ensembl.org/id/ENSGALP00010017235.1" } ] } }, { "isoform_ac": "A0A8V0Y970-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y970/entry", "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAVRNVAVADIIFLVDSSWSIGKEHFQLVREFLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGKGLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDAVEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASADLRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMGDDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCREYLSPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENDLADPCLLDFDMGMQCKDYQVVWFFDYKHKICSQGWYGGCGGNANRFETEAECNSKCLKPSAAEKAMQQPPLEKRLSPVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3015, "header": "tr|A0A8V0Y970-1|A0A8V0YHJ1_CHICK Computationally mapped isoform of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "locus": { "chromosome": "7", "start_pos": 4932339, "end_pos": 4885850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029659.1", "url": "https://www.ensembl.org/id/ENSGALT00010029659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017257.1", "url": "https://www.ensembl.org/id/ENSGALP00010017257.1" } ] } }, { "isoform_ac": "A0A8V0YHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1/entry", "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAVRNVAVADIIFLVDSSWSIGKEHFQLVREFLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGKGLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDAVEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSADPFLQVSNDLARAGVLTFAVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTYVSGGVEEVPLAPTESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASADLRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMGDDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCPCCYGPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENDLADPCLLDFDMGMQCKDYQVVWFFDYKHKICSQGWYGGCGGNANRFETEAECNSKCLKPSAAEKAMQQPPLEKRLSPVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3215, "header": "tr|A0A8V0YHJ1-1|A0A8V0YHJ1_CHICK Isoform 1 of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "locus": { "chromosome": "7", "start_pos": 4932339, "end_pos": 4885850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029636.1", "url": "https://www.ensembl.org/id/ENSGALT00010029636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017245.1", "url": "https://www.ensembl.org/id/ENSGALP00010017245.1" } ] } }, { "isoform_ac": "A0A8V0YHJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ9/entry", "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAVRNVAVADIIFLVDSSWSIGKEHFQLVREFLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGKGLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDAVEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSADPFLQVSNDLARAGVLTFAVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTYVSGGVEEVPLAPTESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVSQNQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKVRCWICRAGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMVSAVMDQLQGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSVSQCALVQNIKDKCREYLSPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3095, "header": "tr|A0A8V0YHJ9-1|A0A8V0YHJ9_CHICK Computationally mapped isoform of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "locus": { "chromosome": "7", "start_pos": 4932339, "end_pos": 4885850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029654.1", "url": "https://www.ensembl.org/id/ENSGALT00010029654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017255.1", "url": "https://www.ensembl.org/id/ENSGALP00010017255.1" } ] } }, { "isoform_ac": "A0A8V0YMB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB7/entry", "sequence": { "sequence": "MRKHRHLPLAAILGLLLSGFCSVGAQQQAAVRNVAVADIIFLVDSSWSIGKEHFQLVREFLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGKGLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDAVEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQESADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYSTKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIVGVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPDLIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERDFVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSADPFLQVSNDLARAGVLTFAVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTYVSGGVEEVPLAPTESKKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELPSKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLKTIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYSNAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQLDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSPVGVKRDVVFLVDGSRYAAQEFYLIRDLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVTTIPDVSGEEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRTHKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILEELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYEDGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAGQNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQPELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASADLRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERTCCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGSSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESGADNTQRGTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERGRIGPLGQKGEPGNPGPRGPNGQQGPRGEMGDDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCPCCYGPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIILPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIRKQCKWLQADQTPKSPGHTGQKAVYIAPNGTVTQTISTTTTLSTTFKPAASTSAHAKTTTASTMAQTRATERPTESTTVQVNATVQSQGSTAANTKATSRTTTSTTAAAASGRRRQGAKMNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSGQKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALANMMLNAEPLEGPENVMDICLLQKEEGTCRNFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISPGVVTTIGT", "length": 3137, "header": "tr|A0A8V0YMB7-1|A0A8V0YMB7_CHICK Computationally mapped isoform of Collagen alpha-3(VI) chain OS=Gallus gallus OX=9031 GN=COL6A3 PE=1 SV=1 CANONICAL=A0A8V0YHJ1-1" }, "locus": { "chromosome": "7", "start_pos": 4932339, "end_pos": 4885850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029644.1", "url": "https://www.ensembl.org/id/ENSGALT00010029644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017248.1", "url": "https://www.ensembl.org/id/ENSGALP00010017248.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2356, "start_aa": "Thr", "end_pos": 2356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2356", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396548", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396548", "resource": "KEGG Pathway" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A087WS16-1", "protein_name": "Collagen, type VI, alpha 3", "gene_name": "Col6a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRKHRHLPLVAVFSLLLSGIATTHAQQHGVMEVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNSYTNKRDAITAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDEVSQPAQELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNMLPSLMAPLRTLTGTTEESKRDILFLFDGSVNVLGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQIVSLLKAEQGSGPVSGEKDVVFLIDGSEGVRSGFPLLKDFVQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERVIQLNREELSSLKPILTPSTGAGVGSKKDVVFLIDGSRNAGPEFQYIRTLIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSDDEVDDSAVELKQFGVAPLTIARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQIHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDIILNRISQIQRISCSGNQLPTVRVSVMANTPSGPVEAFDFAEYQPELFEKFRNMRSQRPYVLTADTLKLYQNKFRQSSPDTVKVVIHFTDGADGDMADLYRASEELRQAGAQALILVGLERVANLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIGPKGISGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPKGETGDIGPMGLPGRDGIPGSPGDPGKDGGSGRRGPAGAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQGIPGPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGSIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQKGDPGYPGPSGHKGNRGDSVDQCALIQSIRDKCPCCYGPLECPVFPTELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTFKRVRSGFLMRKVAVFFSNKPTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTDFLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTDYGAKEKLLDFLSRRMTQLQGTMGLGNAIEYTIENIFESAPNPRDLKIMVLMLTGDMQRQQLEEAQRAILQAKCKGYFFVVLGIGRKVNIKEVYSFASEPNDVFFKFVDKSTELNEEPLMRFGRLLPSFVSSENAFYLPPDLRKQCDWFQGDQPVKNGVKFGHKQINPPHTANSSLTSKVVTTMKPVTTTKPTAIVNLPPAKPAPARPAPAQPVLAKPDPAKPAQARPAPAKPASAKLVPPQPVHVQPAPAQTASVRPAPAKPAPPQPAAAKPVPAKPAVPAQPAPPQPAAAKPVPAKPAVPAQPAPPQPAAAKPVPAKPAVPAQPAAAQPMPAQPVLTKSAAVKPASANKPVAAKPVATNTATATARPALAAKPAAAKPAATRPLAAAIRPVATKPEAPRQQAKPAATKPATTKPLARVSREVQVSEVTENSARLHWERPEPSSSFFYDLTVTSAHDQSLVLRQNLTVTDRVIGGLLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPPLQAAHRASSSTINLMVNTEPLFLTKTDICKLSRDAGTCVDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPDLLV", "length": 2677 }, "evidence": [ { "id": "A0A8V0YHJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZVG7-1", "protein_name": "Collagen alpha-3(VI) chain", "gene_name": "COL6A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRKHRHLPLVAIFCLFFSGFSFTRAQQQADVKKGAAADIIFLVDSSWSIGKEHFQLVREFLYDVIKSLAVGENDFRFALVQFNGNPHTEFLLNTYRSKQDVLSHVSNLSYFGGSNQTGKGLEYVMQNHLTEAAGSRARDGVPQVIVVLTDRPSKDGLVLPSAELKSADVNVFAVGVEDADEGALKEIASEPLNMHVFNLENFTSLHDLVGNLVSCVHSSMTPEGAGGTETLKDITAQESADIIFLIDGSNETGSVHFAVILDFLVNLLERLSVGAQQIRVGVVQYSDEPRTMFSLNSFATKAQVLDAVKALGFLGGELANVGLALDFVVDHHFTRAGGSRVEEGVPQVLVLISAAPSSDKIRDAVLALKQASVFSFGLGAQAASKAELQHIATNDNFVFTVPEFRSFGDLQDQLLPYIVGIAHRHIVLQPPTIVTQVIEVNKRDIVFLVDGSSALGPANFQAIRDFIAKVIQRLDIGQDLIQVAVAQYADTVRPEFYFNTHPNKREVMAAVRRMKPLDGAALYTGSALEFVRNNMFTSEAGYRAAEGVPRLLVLITGGKSLDDVSQPAQELKRSSIMAFAVGNKAADQAELEEIAFDPSLVFIPTEFRASPLQGVLSSLLAPLRTLSGTTEDPAVTLVTMDIIFLLDGSVNVGRTRFPYVRDFVMNLVNSLDVGGDNIRVGLVQFSDTPVTEFSLNTYQTKSDLLAHVRQLQLKGGSGLNTGAALSYVHANHFTEAGGSRIQEQVPQLLLLLTAGPSEDSYLQAANALARSGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSGNLLGQFSAVRDFLYKVIDELDVKPDGTRIAVAQYSDNVRIESSFAEHQTKPEILNLVKRMKLKTGKALNLGYALDFAQRYIFVKSNGSRIEDGVLQILVLLVAGRSSDSVDRPALNLKQSGVVPFILQAKNADPGELELIVPSPAFILAAESLPKIGDLQPHIVNLLKSVQNGAPTPVSGEKDVVFLIDGSEGVRSGFPLLKEFVQRVVESLDVGPDRVRVAVVQYSDRTRPEFYLNSYMDQQSVVNAVRQLTLLGGPIPNTGAALDFVLRDILTESAGSRIAEGIPQLLIVLTADRSGDDVRGPSVVLKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTRLDREELRRLQASVVPLTSVSGKRDVVFLIDGSQTAGPEFQYIRTLIERLVDSLDVGFDTSRVAVIQFSEDPRVEFLLNAHSSKDEVQNAVRRLRPKGGRRINIGGALEYVSKNIFKRPLGSRIEEGVPQFLILISSGKSDDEVDDSAAELKQFGVAPLTIARNADPEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTAEQIQQLLASTRPDIVSMRIDAADIVFLIDSSDGVKPDGIAHIRDFVIRIVRRLNIGPNKVRVGVVQFSNDVFPEFYLKTYRSQASVLDAIRRLRFKGGSPLNTGKALEFVARNFFVKSAGSRIEDGVPQHLVLFLGGKSQDDVSRYSQVMGSSGIVRLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERVMNSFGPSGVTPAPPGKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEGGDSIQVGLVQYNSDPTDEFFLKDFSTKQQIIDAINKVVYKGGRHANTKVGLEHLRLNQFVPEAGSRLEQRVPQIAFVITGGKSVEDAQEASLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDISKACNLEVILGFDGSRDQNIFVAQKGFESKVDTILNRISQMQRISCSGTQMPTVRVSVVATTPAGPVEAFDFAEYQPEMFEKILGMRTQHPYVLTADTLKLYQNKFRQGSPGSVKVSAAALASASWAREADRVQALILVGLERVPNLEQLMQLEFGRGFTYNRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGMNGTQGFQGCPGQRGIKGSRGFPGEKGELGEIGLDGLDGEDGDKGLPGTSGDKGSPGRRGDKGPKGDKGERGDVGIRGDPVRGTFRRPWKMPFPVSSVSVPPHLPPPPRPTGPLECPVFPTELAFALDTSEGVTQDTFSLMRDVVLRIVDELTIAESNCPRGARVAVVTYNNEVITEIRFADSRKKSVLLDKIKNLQVVLTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNKPTRASPQLREAVLKLSDAGITPLFLTSQEDRVLINALQINNTAVGHALVLPARRDLPDFLKNVLTCHVCLDICNIDPSCSLGSWRPSFRDRRAAGSDVDIDMAFIVDSSETTTPFQFNEMRKYIGYVVRQLDLSPDPKASQHFARVAVVQHAPWESVGNASVPPVKVDFSLTDYGSKEKLVAFLSSRMTQLQGTRALGSAIYYTVENVFESAPNPRDLKIVVLMLTGEVQKEQLEEAQRAILQAKCKGYFFVILGIGRKVNVKELYSFASEPNDVFFKLVDKSSELNEEPLMRFGRLLPSFVSSENAFYLSPDVRKQCDWFQGDQPAKNLVKFGHKQVPASKPVTTTKPVTTTEPVTATTKPVTMVNLPASKLAAPKPVAGRPVATKTEATKPEVTKTEAAKPETTKPVAAKPETAKPVAAKPEAAKPVAARPEAAKVHVSEITENSAKLHWERPEPPSPYFYDLTVTSAQDQSLVLKQNLTVPDRVIGGLLAGQTYHVSVVCYLKSQVRATYHGSFSTSKSTVGLWKVASSSTINLMVNTEPLAGSEADVCKLPKDGGTCRKFIIKWYHDAVTGNCARFWYGGCGGNENRFDSQEECEKVCSPGK", "length": 2901 }, "evidence": [ { "id": "A0A8V0YHJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AHL9-1", "protein_name": "Collagen alpha-3(VI) chain", "gene_name": "Col6a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKHRHLPLVAVFSLLLSGITMTHAQQQSDVKNGAAADILFLVDSSWSAGKDRFLLVQEFLSDVVESLSVGDNDFHFALVRLNGNPHTEFLLNAYHSKQEVLSHILNMSYIGESNQTGKGLEYIIHSHLTEASGSRAADGVPQVIVVLTDGQSEEDGFALPSAELKSADVNVFAVGVEDADERTLREIASEPLSMHVFNLENVTSLHDMVGNLVSCIHSSVNPERAGDKESLKDITAQDSADIIFLIDGSQNTGKANFDVIRDFLVNVLERLSVGNQQVRVGVVQYSDEPRTMFSLDSYPSKAAVLDAVKRLSFAGGELANIGQALDFVVENHFTRTGGSRVEEGVPQVLVLISAGPSSDEIRDAVVALKQGSVFSFGLGAQAASRVELQHIATDDNLVFTVPEFRSFGDLQEQLLPYLVGVAQRHFVLQPPAIVTQVMEVNKRDIVFLVDGSSSLGQANFNAIRDFISRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNTYSTKKDAITTVRKMKALEGSALYTGSALDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDDVSQAAQELQKGSIMALVIGSRAADEDELKEIAFDSSLVFIPAEFRPAPLQSMLPSLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGTGLNAGSALSYVHANHFTEAGGSRIREHVPQLLLLLMAGPSEDVYLQAANALVRSGVLTFCVGTNQADKAELERIAFNPSLVYLMDDFSALPALPQQLIQPLTTYVSGGVQEVPLSQPEVKRDILFLFDGSVNVMGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRVESRFNEHQTKAEILNLVKKMKLKTGKGLNLGLALDHALRTIFVRSAGSRIEDNVQQFLVLLVAGRSTDAVAGPASSLKQRGVIPFIFQAKNANPSELEQIVPSPAFILAAESLPKIGDLQSEIVGLLKAKQTSDTVSGEKDVVFLIDGSEGVRSGFPLLKEFVQRVVESLDVGPNQVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALDFVLRNILTSSTGSRIEEGVPQLLIVLTAERSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERVIQLNREQLSSLTPVLMPSPSAGPGNKKDVVFLIDGSQNAGAEFQHIRTLIERLVEYLDIGFDTTRVAVIQFSEDTKMEFPLNAHFSKDEVQNAVRRLRPKGGRQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSADEVDDSAVELKQFGVAPLTVARHTDQEELVKISLSPEYVFSVSTFRELPRLEQRLLTPITTLTSQQIQQILASTRYPPSVAESDAADIVFLIDSSDAMKPDGIAHIRDFVSRIVRRLNIGPNKVRIGVVQFSNDVFPEFYLKTHKSQNSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVSRHAQVISSSGIMSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGPTPQPPEVEFPSSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVIYKGGRHANTRVGIEHLLKNHFVSEAGSRLDERVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDTILNRISQIQRISCSSNQLPTVRVSVVANTPSGPVEAFDFAEYQPDLFEKFRTMRSQHPYVLTADTLKLYQNKFRQSSPDTVKVVIHFTDGADGDMADLYRASEELRQAGVQALILVGLERVANLERLMQVEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIGPKGISGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPKGETGDIGPMGLPGRDGIPGSPGDPGKDGGFGRRGPAGAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQGIPGPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGGTGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGVVGQKGDPGYPGPSGHRGNRGDSVDQCALIQSIRDKCPCCYGPLECPVFPTELAFALDTSEGVTQDTFSRMREVLLSIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKKKSALLDSIQNLQVALTSKQPSLETAMSFVARNTFKRVRNGFLMRKVAIFFSNQPTKPSLQLREAVLKLSDAGITPLFLTSQEDRELINALQINNTAVGHALVLPARRDLRDFLKNVLTCHVCLDICNIDPSCGFGNWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYISYMVRQLDLSPDPKASQHFARVAVVQQATYESVDNTSVPPVKVEFSLTDYGAKEKLLDFLSRRMTQLQGTMDLGNAIEYTIENIFESAPNPRDLKIVVLMLTGEIPREQLEEAQRAILQAKCKGYFFVVLGIGRKVNVKEVYSFASEPNDVFFKFMDKSTELNEEPLMRFGRLLPSFVGSGNAFYLPPDLRKQCDWFQGDQPVKNGVKFGHRQINTPHTVNSSLTSKVVTTMKPVTTTKPTSIVNLPPAKPAPVRPAPAQPVLAKPDPAKPVSAKSVPPQPVHAQPDPAQPVHVQSASAQTASAKPAPAKPAPPQTAAAKPAPPQTAAAKPAPPQTAAAKPAPPQTAAAKPVPVKPAPAQPVHVQSASAQTASAKPVPAKPAPPQTAAAKPVPVKPAVPAQPAPAQPVHAQPAPAQPVLTKPAAMKPASANKPVAAKPVATNTATVRPASAVKPAAASKPAATRPLPAAVRPVATKPEAPRPQAKPAATKPATTKPMARVSREVQVSEVTENSARLHWERPEPSSSYFYDLTVTSAHDQSLVLRQNLTVTDRVIGGLLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPVLQAAHRASSSTINLMVNTEPLFLTKTDICKLPKDAGTCEDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPELSV", "length": 3316 }, "evidence": [ { "id": "A0A8V0YHJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12111-1", "protein_name": "Collagen alpha-3(VI) chain", "gene_name": "COL6A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT", "length": 3177 }, "evidence": [ { "id": "A0A8V0YHJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "collagen type VI trimer", "id": "GO:0005589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2084, "end_pos": 2086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2436, "end_pos": 2438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2563, "end_pos": 2565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2581, "end_pos": 2583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2683, "end_pos": 2685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2867, "end_pos": 2869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2920, "end_pos": 2922, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3003, "end_pos": 3005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3204, "end_pos": 3206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 3073, "end_pos": 3124, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 2957, "end_pos": 3051, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ1" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 212, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 2084, "end_pos": 2086 }, { "start_pos": 2436, "end_pos": 2438 }, { "start_pos": 2563, "end_pos": 2565 }, { "start_pos": 2581, "end_pos": 2583 }, { "start_pos": 2683, "end_pos": 2685 }, { "start_pos": 2867, "end_pos": 2869 }, { "start_pos": 2920, "end_pos": 2922 }, { "start_pos": 3003, "end_pos": 3005 }, { "start_pos": 3204, "end_pos": 3206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"MLAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGIGGIASMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGVSAVSSVSVDQRLPEEPALEEEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGKLIPEKQLLNDQLKQVQQNSLHRDSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNRQQLQKQKNLEAERLKQKEQERKTELEKQKEAQRRIQDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPSKLFQPHQEPVKPAVQAPWSNAGKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTECTTTANNWADFSSTWPANTNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKATMSGEEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTSKTTPTELPKSTALPSVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINESFKGLMQMYLMYTFRSQRATGIGRLMVNIVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTMQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "length": 1674, "header": "tr|A0A8V0YF29-1|A0A8V0YF29_CHICK Isoform 1 of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9F5/entry", "sequence": { "sequence": "MLAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGIGGIASMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGVSAVSSVSVDQRLPEEPALEEEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGKLIPEKQLLNDQLKQVQQNSLHRDSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNRQQLQKQKNLEAERLKQKEQERKTELEKQKEAQRRIQDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPSKLFQPHQEPVKPAVQAPWSNAGKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTECTTTANNWADFSSTWPANTNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKATMSGEEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTSKTTPTELPKSTALPSVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQCK", "length": 1119, "header": "tr|A0A8V0Y9F5-1|A0A8V0YF29_CHICK Computationally mapped isoform of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105650240, "end_pos": 105585985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029797.1", "url": "https://www.ensembl.org/id/ENSGALT00010029797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017349.1", "url": "https://www.ensembl.org/id/ENSGALP00010017349.1" } ] } }, { "isoform_ac": "A0A8V0Y9U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U7/entry", "sequence": { "sequence": "PELCFPSNLDIWAITVEERAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGNMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFSSVSVDQRLPEEPALEEEQQQLEKKLPDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERRECQSFSLIFLGIGDIHGFPAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGKLIPEKQLLNDQLKQVQQNRDSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKEDVKIVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTECTTTANNWADFSSTYVWPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYIIFYSALQMIIEQFIKCFPMLCIYFLLAEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTKLFLYLTVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTMQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLSCHKTLIGLV", "length": 1504, "header": "tr|A0A8V0Y9U7-1|A0A8V0YF29_CHICK Computationally mapped isoform of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105669139, "end_pos": 105585713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030122.1", "url": "https://www.ensembl.org/id/ENSGALT00010030122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017497.1", "url": "https://www.ensembl.org/id/ENSGALP00010017497.1" } ] } }, { "isoform_ac": "A0A8V0Y9W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9W5/entry", "sequence": { "sequence": "AEKMKVELRSMLLEHSTVESNLDIWAITVEERAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGNMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPGMLHTEPLCTILLLTNQWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFSLILLCPMFPHIKVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQVRKFFSFCSQSYSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPRKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTESQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYIIFYSALQMIIEQFIKCFPMLCIYFLLAEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTKLFLYLTVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTMQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLSCHKTLIGLV", "length": 1535, "header": "tr|A0A8V0Y9W5-1|A0A8V0YF29_CHICK Computationally mapped isoform of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105669139, "end_pos": 105585528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030150.1", "url": "https://www.ensembl.org/id/ENSGALT00010030150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017512.1", "url": "https://www.ensembl.org/id/ENSGALP00010017512.1" } ] } }, { "isoform_ac": "A0A8V0YF29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF29/entry", "sequence": { "sequence": "MLAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGIGGIASMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGVSAVSSVSVDQRLPEEPALEEEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGKLIPEKQLLNDQLKQVQQNSLHRDSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNRQQLQKQKNLEAERLKQKEQERKTELEKQKEAQRRIQDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPSKLFQPHQEPVKPAVQAPWSNAGKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTECTTTANNWADFSSTWPANTNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKATMSGEEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTSKTTPTELPKSTALPSVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINESFKGLMQMYLMYTFRSQRATGIGRLMVNIVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTMQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "length": 1674, "header": "tr|A0A8V0YF29-1|A0A8V0YF29_CHICK Isoform 1 of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105669043, "end_pos": 105585985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030163.1", "url": "https://www.ensembl.org/id/ENSGALT00010030163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017517.1", "url": "https://www.ensembl.org/id/ENSGALP00010017517.1" } ] } }, { "isoform_ac": "A0A8V0YFW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW0/entry", "sequence": { "sequence": "MLAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGIGGIASMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGVSAVSSVSVDQRLPEEPALEEEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGKLIPEKQLLNDQLKQVQQNRDSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNRQQLQKQKNLEAERLKQKEQERKTELEKQKEAQRRIQDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPSKLFQPHQEPVKPAVQAPWSNAGKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMVRTDCDIIVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTECTTTANNWADFSSTWPANTNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKATMSGEEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTSKTTPTELPKSTALPSVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELNTSGAITRRADASISW", "length": 1467, "header": "tr|A0A8V0YFW0-1|A0A8V0YFW0_CHICK Computationally mapped isoform of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105666462, "end_pos": 105585985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029919.1", "url": "https://www.ensembl.org/id/ENSGALT00010029919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017413.1", "url": "https://www.ensembl.org/id/ENSGALP00010017413.1" } ] } }, { "isoform_ac": "A0A8V0YG20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG20/entry", "sequence": { "sequence": "PELCFPSNLDIWAITVEERAKHDQQFHSLKPTSGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYQLPSALPPVMKQPPIALPSAPGFGNMPSLTTVAPVPMASIPVVGMSPPLVSSVPAAAVPPLANGAPAVIQPLPAFAHPGMLHTEPLCTILLLTNQWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFSSVSVDQRLPEEPALEEEQQQLEKKLPDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKNQLEGKLQDIRCRLSTQRQEIESTNKSRELRIAEITHLQQQLQVRKFFSFCSQSYSLLTIKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKDRDKQRLDRVQQEEEPQWQKKNQEDDKQKREEIIKKKESEDKGKQEIQEKPSKLFQPHQEPVKPAVQAPWSNAVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPESEVPASIKPAEAAPAPKVSVHETTTSLGTAASTESQPSLTVPSAGQLRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYIIFYSALQMIIEQFIKCFPMLCIYFLLAEYVAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGTLGDKTGVFPSNYVRLKDSEASGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQGKKRQIGWFPANYVKLLSPGTKLFLYLTVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTMQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLSCHKTLIGLV", "length": 1539, "header": "tr|A0A8V0YG20-1|A0A8V0YG20_CHICK Computationally mapped isoform of Intersectin-1 OS=Gallus gallus OX=9031 GN=ITSN1 PE=1 SV=1 CANONICAL=A0A8V0YF29-1" }, "locus": { "chromosome": "1", "start_pos": 105669139, "end_pos": 105585713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030078.1", "url": "https://www.ensembl.org/id/ENSGALT00010030078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017474.1", "url": "https://www.ensembl.org/id/ENSGALP00010017474.1" } ] } }, { "isoform_ac": "A0A8V0YG52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG52/entry", "sequence": { "sequence": 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"start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF29" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 717, "end_pos": 778, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1525, "end_pos": 1527 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFX3-1", "uniprot_ac": "A0A8V0YFX3", "uniprot_id": "A0A8V0YFX3_CHICK", "mass": { "chemical_mass": 82467.0, "monoisotopic_mass": 82467.0 }, "refseq": { "ac": "XP_015137163", "name": "nuclear protein MDM1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137163" }, "gene_names": [ { "name": "MDM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ] }, { "name": "MDM1", "type": "synonym", "evidence": [ { "id": "XP_015137163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137163" } ] } ], "protein_names": [ { "name": "Nuclear protein MDM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3/entry#names_and_taxonomy" } ] }, { "name": "nuclear protein MDM1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137163" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015137163.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137163" } ] }, { "annotation": "Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET7#function" }, { "database": "UniProtKB", "id": "ARBA00045771", "url": "https://www.uniprot.org/uniprotkb/ARBA00045771#function" }, { "database": "UniProtKB", "id": "A0A8V0YEU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU2#function" }, { "database": "UniProtKB", "id": "A0A8V0YEU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU6#function" }, { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9M5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MDM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3", "locus": { "chromosome": "1", "start_pos": 35240495, "end_pos": 35264677, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012508", "url": "https://www.ensembl.org/id/ENSGALG00010012508" } ] } } ], "crossref": [ { "id": "A0A8V0YFX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417839", "url": "https://www.ncbi.nlm.nih.gov/gene/417839", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LAWGEQD", "url": "https://omabrowser.org/oma/group/LAWGEQD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9M5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YET7", "url": "https://www.orthodb.org/?gene=A0A8V0YET7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEU2", "url": "https://www.orthodb.org/?gene=A0A8V0YEU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEU6", "url": "https://www.orthodb.org/?gene=A0A8V0YEU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX3", "url": "https://www.orthodb.org/?gene=A0A8V0YFX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32078:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32078:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YET7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YET7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "length": 738, "header": "tr|A0A8V0YFX3-1|A0A8V0YFX3_CHICK Isoform 1 of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9M5/entry", "sequence": { "sequence": "MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEVFTEVSGRGTILRSPDKGDCM", "length": 723, "header": "tr|A0A8V0Y9M5-1|A0A8V0YFX3_CHICK Computationally mapped isoform of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "locus": { "chromosome": "1", "start_pos": 35264611, "end_pos": 35241973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029974.1", "url": "https://www.ensembl.org/id/ENSGALT00010029974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017427.1", "url": "https://www.ensembl.org/id/ENSGALP00010017427.1" } ] } }, { "isoform_ac": "A0A8V0YET7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET7/entry", "sequence": { "sequence": "MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "length": 647, "header": "tr|A0A8V0YET7-1|A0A8V0YFX3_CHICK Computationally mapped isoform of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "locus": { "chromosome": "1", "start_pos": 35264611, "end_pos": 35241704, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029989.1", "url": "https://www.ensembl.org/id/ENSGALT00010029989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017431.1", "url": "https://www.ensembl.org/id/ENSGALP00010017431.1" } ] } }, { "isoform_ac": "A0A8V0YEU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU2/entry", "sequence": { "sequence": "MPGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "length": 734, "header": "tr|A0A8V0YEU2-1|A0A8V0YFX3_CHICK Computationally mapped isoform of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "locus": { "chromosome": "1", "start_pos": 35264611, "end_pos": 35241704, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030000.1", "url": "https://www.ensembl.org/id/ENSGALT00010030000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017436.1", "url": "https://www.ensembl.org/id/ENSGALP00010017436.1" } ] } }, { "isoform_ac": "A0A8V0YEU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU6/entry", "sequence": { "sequence": "MPGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "length": 721, "header": "tr|A0A8V0YEU6-1|A0A8V0YFX3_CHICK Computationally mapped isoform of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "locus": { "chromosome": "1", "start_pos": 35264611, "end_pos": 35241704, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030006.1", "url": "https://www.ensembl.org/id/ENSGALT00010030006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017441.1", "url": "https://www.ensembl.org/id/ENSGALP00010017441.1" } ] } }, { "isoform_ac": "A0A8V0YFX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3/entry", "sequence": { "sequence": "MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNVSKPVPPLKSPAITSETENVRNLKGSPAAKGPQEKCSEEKEFLVHEQTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTEEKDSQQLTEEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLLNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "length": 738, "header": "tr|A0A8V0YFX3-1|A0A8V0YFX3_CHICK Isoform 1 of Nuclear protein MDM1 OS=Gallus gallus OX=9031 GN=MDM1 PE=1 SV=1 CANONICAL=A0A8V0YFX3-1" }, "locus": { "chromosome": "1", "start_pos": 35264611, "end_pos": 35241704, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029982.1", "url": "https://www.ensembl.org/id/ENSGALT00010029982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017429.1", "url": "https://www.ensembl.org/id/ENSGALP00010017429.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1SH67-1", "protein_name": "Nuclear protein MDM1", "gene_name": "MDM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPVRFKGLSEYQRNFLWKKSYLSESYNPSVGRRYPWAGLRSDQLGITKEPSFISKRRVPHHDPQISKSLEWNGATSEKDVVLSPEPEGPRTPESQEAEKKEDINQERVLALEASRVPKRTRSHSADSRAEGASDIVENKEDIAANHVPVSENVELEHSTKLLSENVDDGLDRLLRKKAGLTVVPTRNTLRNSEYQRQFVWKTPKETAPAFAANQVFHNKSKFVPQFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLKENRNFEIISPEKKCNKTDDPLKLEAEMESKDSNQPKKKVTPWKHQRLGKVNSEYRAKFLSPSQYLYKAGAWTRVKENIPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDNNRCWDVSSTTSSEGTISSNIRALDLAGDPTSLKASQKCPTKLEERTSVLEEQPEKTTTEKLDVSDAPIPVRRRLAWDAENTTEDQKHLREEEEEEEKEERDKQVNVGELEKLEVQEESKADKMQEGSESSSVSSGKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKVKPPVPEQKKRTSSQDGLEALKNDFRKKESRAISLLTSPAAGLKTVDPLPLREDSEPNISRSAEATLPVSKIPDYPTNTPKQSPSPPVPHPTGIQLVEFRAP", "length": 655 }, "evidence": [ { "id": "A0A8V0YFX3", "url": "https://omabrowser.org/oma/group/A0A8V0YFX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5PQN4-1", "protein_name": "Stabilizer of axonemal microtubules 6", "gene_name": "Saxo6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVRFKGLSEYQRNFLWKKSYLSESYNPSVGQKYTWAGLRSDQLGITKEPSFISKRRVPYYDPQISKYLEWNGTVRENDALAPPEPQIIRTPKPQEAEQREDANHETVLPQEASRVPKRTRSHSADSRAEGASDGVEKHQDVTKNHSLVNADVELRPSTKPLPESIEPRLDRHLRKKAGLAVVPLNNALRNSEYQRQFVWKTCKETAPVCAANQVFRNKSQVIPQFQGNTFIHESEYKRNFKGLTPVKEPKLREYLKGNSSFEILSPEKKADEPLDLEVDMASEDSDQPIKKPAPWRHQRLGKVNSEYRAKFLSPAQYLYKAGAWTRVKESLSHQGSLNAMWYAEVKELREKAESYRKRVQGTHFSRDHLNQIMSDSNCCWDVSSVASSEGTISSNIQALDLAGDLTSHRTLQKHPPTKLEEKKVALAEQPLENTIRSLELPEAPTMARRKLAWDAAEGTQKEDTQEEPSGEEDGREARGKDKQVCAGELQKVDMQTSKADGPTEGSETSSVSSGKGGRLPTPRLRELGIQRTHHDLTTPAVGGAVLVSPAKAKPSALEQRRRPSSQDGLETLKKGITKKGKHRPLSLLTSPTAGMKTVDPLPLRQDCDANVLRVAEGTLPVLKNLDHQTNTPGQPSPCTLPYCHPSSRIQGRLRDPEFQHNIGKPRMNNTQLLPHGAFNDEDADRLSEISARSAVSSLQAFQTLARAQKRKENFWGKP", "length": 719 }, "evidence": [ { "id": "A0A8V0YFX3", "url": "https://omabrowser.org/oma/group/A0A8V0YFX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RHU7-1", "protein_name": "Stabilizer of axonemal microtubules 6", "gene_name": "saxo6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVRFKGISEYRSKYKGRTSRSRSDSPHRRMRLAGLRSDQSGITQEPQFISKRRVPFYPSQVSSSFRWEGRDHSQQQLEKSRSPAVSPVLRATSAERQVTPLAPRDPPEGTTAPSQPPQAEAAQTSTFAVQKQKQALNGINHALRMKAGLRSEHQRNGLNSEYQRQFMWKTPVAESPLLAAHQMLYSNNRAIPPFKTNPVIMESEYKRSFKGSPLPRPPRLRRDVEQYEVPEFLTESKTPEKSKRKKKKKERPHSRKSSPEQEVAYLQQQEVKSPHNLKDPSPKVMRKGKTEYRSNFHSPLQYSYKDGAWLKIKSAKEEVKELRERAEAYKKRAWGTHFSRQHLNQILSDQNWMWEPSSGTSSSSIESEACRSTSHIIEALDLARAGSVRESSSPGHSASVVVSRRSSSGEVGLPEEPTLPVQRKLAWDEEEQLGEREEIVQDRLTDKEGKTRNENGMERNERLNSLESESLSSAEEGSEASVNGGRLPTPKLKTMQTVQRTHHDRTTPSIDFNLHYIAKAANGSLPRSSPVAGLTTVDVLPMREDVWSDEEVTDYRSLKPPKPSRKQQSSQRHKANAAPPANRIQGTMRNAEFQHNGNLGIFRPELFVLPQSDSALSDNDDKMSQISSRSAASCSMASEVLGRAQRRKQEFWGKS", "length": 656 }, "evidence": [ { "id": "A0A8V0YFX3", "url": "https://omabrowser.org/oma/group/A0A8V0YFX3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of centriole replication", "id": "GO:0046600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 389, "end_pos": 391 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A8V0YG47-1", "uniprot_ac": "A0A8V0YG47", "uniprot_id": "A0A8V0YG47_CHICK", "mass": { "chemical_mass": 98239.0, "monoisotopic_mass": 98239.0 }, "refseq": { "ac": "XP_015144753", "name": "arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144753" }, "gene_names": [ { "name": "AGAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ] }, { "name": "AGAP1", "type": "synonym", "evidence": [ { "id": "XP_015144753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144753" } ] } ], "protein_names": [ { "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47/entry#names_and_taxonomy" } ] }, { "name": "Centaurin-gamma-2", "type": "synonym", "evidence": [ { "id": "A0A8V0YG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_015144753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144753" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144753" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47", "locus": { "chromosome": "7", "start_pos": 5266055, "end_pos": 5556030, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012571", "url": "https://www.ensembl.org/id/ENSGALG00010012571" } ] } } ], "crossref": [ { "id": "A0A8V0YG47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG47", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04103", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04103", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424024", "url": "https://www.ncbi.nlm.nih.gov/gene/424024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein 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"Protein Classification" ] }, { "id": "PTHR45819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45819:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45819:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144753", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTTSTSVSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSGISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGISGTAEAKRKAWKLNRVGSLRNIYSSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 888, "header": "tr|A0A8V0YG47-1|A0A8V0YG47_CHICK Isoform 1 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9V2/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTTSTSVSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSGISSEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 808, "header": "tr|A0A8V0Y9V2-1|A0A8V0YG47_CHICK Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "locus": { "chromosome": "7", "start_pos": 5555909, "end_pos": 5268165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030133.1", "url": "https://www.ensembl.org/id/ENSGALT00010030133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017502.1", "url": "https://www.ensembl.org/id/ENSGALP00010017502.1" } ] } }, { "isoform_ac": "A0A8V0YF23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF23/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGISGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 752, "header": "tr|A0A8V0YF23-1|A0A8V0YF23_CHICK Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "locus": { "chromosome": "7", "start_pos": 5555909, "end_pos": 5268165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030149.1", "url": "https://www.ensembl.org/id/ENSGALT00010030149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017511.1", "url": "https://www.ensembl.org/id/ENSGALP00010017511.1" } ] } }, { "isoform_ac": "A0A8V0YG47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTTSTSVSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSGISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGISGTAEAKRKAWKLNRVGSLRNIYSSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 888, "header": "tr|A0A8V0YG47-1|A0A8V0YG47_CHICK Isoform 1 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "locus": { "chromosome": "7", "start_pos": 5555909, "end_pos": 5268165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030127.1", "url": "https://www.ensembl.org/id/ENSGALT00010030127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017499.1", "url": "https://www.ensembl.org/id/ENSGALP00010017499.1" } ] } }, { "isoform_ac": "A0A8V0YG57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG57/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQEWNHLGKNKGSEFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGISGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 816, "header": "tr|A0A8V0YG57-1|A0A8V0YG57_CHICK Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "locus": { "chromosome": "7", "start_pos": 5555909, "end_pos": 5268165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030145.1", "url": "https://www.ensembl.org/id/ENSGALT00010030145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017509.1", "url": "https://www.ensembl.org/id/ENSGALP00010017509.1" } ] } }, { "isoform_ac": "A0A8V0YI78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI78/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEVSFQTVYHYYSRMANYRNTSEIPMVLVGTQDAISSSNPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKVLESRTDSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGISGTAEAKRKAWKLNRVGSLRNIYSSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQNEAMALQSIRNIRGNSHCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGHMKPSSDSTREEKERWIRAKYEQKLFLAPLQCLELSLGQHLLRATAEEDLRTVILLLAHGTREEVNETCGDGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNNRNNSSGRMPTII", "length": 834, "header": "tr|A0A8V0YI78-1|A0A8V0YI78_CHICK Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Gallus gallus OX=9031 GN=AGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG47-1" }, "locus": { "chromosome": "7", "start_pos": 5555909, "end_pos": 5268165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030140.1", "url": "https://www.ensembl.org/id/ENSGALT00010030140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017505.1", "url": "https://www.ensembl.org/id/ENSGALP00010017505.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 640, "end_pos": 760, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG47" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 619, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 289 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 869, "end_pos": 871 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 879, "end_pos": 881 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG86" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"https://www.ncbi.nlm.nih.gov/protein/NP_989453" } ] } ], "protein_names": [ { "name": "Receptor-type tyrosine-protein phosphatase O", "type": "recommended", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5/entry#names_and_taxonomy" } ] }, { "name": "Glomerular epithelial protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5/entry#names_and_taxonomy" } ] }, { "name": "Protein tyrosine phosphatase U2", "type": "synonym", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5/entry#names_and_taxonomy" } ] }, { "name": "extracellular protein tyrosine phosphatase CRYP-2", "type": "synonym", "evidence": [ { "id": "NP_989453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989453" } ] }, { "name": "receptor-type tyrosine-protein phosphatase O", "type": "synonym", "evidence": [ { "id": "NP_989453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989453" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: U65891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_989453.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989453" } ] }, { "annotation": "Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5#function" }, { "database": "UniProtKB", "id": "ARBA00056314", "url": "https://www.uniprot.org/uniprotkb/ARBA00056314#function" }, { "database": "UniProtKB", "id": "A0A8V0YAB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB2#function" }, { "database": "UniProtKB", "id": "A0A8V0YFK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK8#function" }, { "database": "UniProtKB", "id": "A0A8V0YAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPRO", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5", "locus": { "chromosome": "1", "start_pos": 62990143, "end_pos": 62808411, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012702", "url": "https://www.ensembl.org/id/ENSGALG00010012702" } ] } } ], "crossref": [ { "id": "A0A8V0YGL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14614", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14614", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "373911", "url": "https://www.ncbi.nlm.nih.gov/gene/373911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:373911", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TISFITX", "url": "https://omabrowser.org/oma/group/TISFITX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAA7", "url": "https://www.orthodb.org/?gene=A0A8V0YAA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAB2", "url": "https://www.orthodb.org/?gene=A0A8V0YAB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFK8", "url": "https://www.orthodb.org/?gene=A0A8V0YFK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGL5", "url": "https://www.orthodb.org/?gene=A0A8V0YGL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIM4", "url": "https://www.orthodb.org/?gene=A0A8V0YIM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47028:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47028:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26586", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26586", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPQFAIAGHGSEPGGGRRGAAARGRGAEEPQPPPPGRSRGPRPPRSPMPDRRRRGARGGPGARSCLLWLFVLLKNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1268, "header": "tr|A0A8V0YGL5-1|A0A8V0YGL5_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase O OS=Gallus gallus OX=9031 GN=PTPRO PE=3 SV=1 CANONICAL=A0A8V0YGL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA7/entry", "sequence": { "sequence": "MLYMWSMFLSELPKNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1179, "header": "tr|A0A8V0YAA7-1|A0A8V0YGL5_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase O OS=Gallus gallus OX=9031 GN=PTPRO PE=3 SV=1 CANONICAL=A0A8V0YGL5-1" }, "locus": { "chromosome": "1", "start_pos": 62987660, "end_pos": 62916702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030451.1", "url": "https://www.ensembl.org/id/ENSGALT00010030451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017664.1", "url": "https://www.ensembl.org/id/ENSGALP00010017664.1" } ] } }, { "isoform_ac": "A0A8V0YAB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB2/entry", "sequence": { "sequence": "MLPQFAIAGHGSEPGGGRRGAAARGRGAEEPQPPPPGRSRGPRPPRSPMPDRRRRGARGGPGARSCLLWLFVLLKNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1240, "header": "tr|A0A8V0YAB2-1|A0A8V0YGL5_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase O OS=Gallus gallus OX=9031 GN=PTPRO PE=3 SV=1 CANONICAL=A0A8V0YGL5-1" }, "locus": { "chromosome": "1", "start_pos": 62987660, "end_pos": 62841224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030460.1", "url": "https://www.ensembl.org/id/ENSGALT00010030460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017669.1", "url": "https://www.ensembl.org/id/ENSGALP00010017669.1" } ] } }, { "isoform_ac": "A0A8V0YFK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK8/entry", "sequence": { "sequence": "MPQGSEQNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1172, "header": "tr|A0A8V0YFK8-1|A0A8V0YFK8_CHICK Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase O OS=Gallus gallus OX=9031 GN=PTPRO PE=3 SV=1 CANONICAL=A0A8V0YGL5-1" }, "locus": { "chromosome": "1", "start_pos": 62987660, "end_pos": 62808519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030468.1", "url": "https://www.ensembl.org/id/ENSGALT00010030468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017673.1", "url": "https://www.ensembl.org/id/ENSGALP00010017673.1" } ] } }, { "isoform_ac": "A0A8V0YGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5/entry", "sequence": { "sequence": "MLPQFAIAGHGSEPGGGRRGAAARGRGAEEPQPPPPGRSRGPRPPRSPMPDRRRRGARGGPGARSCLLWLFVLLKNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPMNRCKNRYTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1268, "header": "tr|A0A8V0YGL5-1|A0A8V0YGL5_CHICK Isoform 1 of Receptor-type tyrosine-protein phosphatase O OS=Gallus gallus OX=9031 GN=PTPRO PE=3 SV=1 CANONICAL=A0A8V0YGL5-1" }, "locus": { "chromosome": "1", "start_pos": 62987660, "end_pos": 62841224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030454.1", "url": "https://www.ensembl.org/id/ENSGALT00010030454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017666.1", "url": "https://www.ensembl.org/id/ENSGALP00010017666.1" } ] } }, { "isoform_ac": "A0A8V0YIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM4/entry", "sequence": { "sequence": "MEKSPLGPISRGKGNAEPFQVTVQEDNCIVVSLEASDVVSSSSVYVVKIAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPLPVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINRNNWEEHSGNFAEESFMGQQEIISKEKLSRFPSDPPEIPVVNTTAAWPDYRSNSTEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGASEANASGKLTAEPAPFLPVQMVLTWLPPKPPTAFDGFHINIEREENSTELLTVSEDTHKFVAELKEPGKYKLSVTTFSSSGSCEVRGSQSTKTLSFYISPTGEWIEELTEKPQHVTVTVLSSTTALTSWTASHESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPLVGPPSDPVTFSIVPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTSEWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSVTRSVMTAVLSLPPGDIYNLSVTACTERGSNTSLPQLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVYCQQAGSNQEVKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHNSPSVPTYIAVSTMVTEMNPNIVVISVLAILSILLIGLLLVTLVVLRRKHLQMARECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDGYIKDMAKDSDYKFSLQFEVNLQHFPRCGSASHLILQNFKGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEDPIAYGDITVEMLSEEEHTDWVYRNFRISYADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQKKKQQFCISDVIYENVSKS", "length": 1172, "header": "tr|A0A8V0YIM4-1|A0A8V0YIM4_CHICK Computationally mapped isoform of Protein tyrosine phosphatase, receptor type O OS=Gallus gallus OX=9031 GN=PTPRO PE=4 SV=1 CANONICAL=A0A8V0YGL5-1" }, "locus": { "chromosome": "1", "start_pos": 62987660, "end_pos": 62924569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030442.1", "url": "https://www.ensembl.org/id/ENSGALT00010030442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017657.1", "url": "https://www.ensembl.org/id/ENSGALP00010017657.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 596, "start_aa": "Thr", "end_pos": 596, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr596", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:373911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q612-1", "protein_name": "Receptor-type tyrosine-protein phosphatase O", "gene_name": "Ptpro", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS", "length": 1226 }, "evidence": [ { "id": "A0A8V0YGL5", "url": "https://omabrowser.org/oma/group/A0A8V0YGL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q16827-1", "protein_name": "Receptor-type tyrosine-protein phosphatase O", "gene_name": "PTPRO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS", "length": 1216 }, "evidence": [ { "id": "A0A8V0YGL5", "url": "https://omabrowser.org/oma/group/A0A8V0YGL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "glomerulus development", "id": "GO:0032835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "slit diaphragm assembly", "id": "GO:0036060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "regulation of glomerular filtration", "id": "GO:0003093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "monocyte chemotaxis", "id": "GO:0002548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "podocyte differentiation", "id": "GO:0072112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" }, { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1148, "end_pos": 1150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1264, "end_pos": 1266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-NUL-9603766", "name": "PTPRO dephosphorylate NTRK3", "equation": "", "summary": "Recombinant chicken protein tyrosine phosphatase PTPRO dephosphorylates recombinant human NTRK3 (TRKC), activated by recombinant human NTF3 (NT-3) (Hower et al. 2009).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YGL5-1" ], "evidence": [ { "id": "R-NUL-9603766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-NUL-9603766" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YGL5", "gene_name": "PTPRO", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 380, "end_pos": 476, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 1164, "end_pos": 1238, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL5" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 990, "end_pos": 1247, "start_aa": "Phe", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": 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842, "end_pos": 844 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGX3-1", "uniprot_ac": "A0A8V0YGX3", "uniprot_id": "A0A8V0YGX3_CHICK", "mass": { "chemical_mass": 122241.0, "monoisotopic_mass": 122241.0 }, "refseq": { "ac": "XP_003643003", "name": "AP-3 complex subunit beta-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643003" }, "gene_names": [ { "name": "AP3B1", "type": "recommended", "evidence": [ { "id": "A0A8V0YGX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3" } ] }, { "name": "AP3B1", "type": "synonym", "evidence": [ { "id": "XP_003643003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643003" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit beta", "type": "recommended", "evidence": [ { "id": "A0A8V0YGX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3/entry#names_and_taxonomy" } ] }, { "name": "AP-3 complex subunit beta-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003643003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643003" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643003.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643003" } ] }, { "annotation": "Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU1#function" }, { "database": "UniProtKB", "id": "ARBA00023570", "url": "https://www.uniprot.org/uniprotkb/ARBA00023570#function" }, { "database": "UniProtKB", "id": "A0A8V0YIY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIY2#function" }, { "database": "UniProtKB", "id": "A0A8V0YAI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAI9#function" }, { "database": "UniProtKB", "id": "A0A8V0YGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV9#function" }, { "database": "UniProtKB", "id": "A0A8V0YGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3#function" }, { "database": "UniProtKB", "id": "A0A8V0YIV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP3B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3", "locus": { "chromosome": "Z", "start_pos": 23489211, "end_pos": 23329518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012751", "url": "https://www.ensembl.org/id/ENSGALG00010012751" } ] } } ], "crossref": [ { "id": "A0A8V0YGX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "427646", "url": "https://www.ncbi.nlm.nih.gov/gene/427646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002553", "url": 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Classification" ] }, { "id": "IPR029394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427646", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFNPIDS", "url": "https://omabrowser.org/oma/group/TFNPIDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAG8", "url": "https://www.orthodb.org/?gene=A0A8V0YAG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAI9", "url": "https://www.orthodb.org/?gene=A0A8V0YAI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFU1", "url": "https://www.orthodb.org/?gene=A0A8V0YFU1", "database": "OrthoDB", "categories": 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"Protein Classification" ] }, { "id": "PTHR11134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24080", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24080", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643003", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1100, "header": "tr|A0A8V0YGX3-1|A0A8V0YGX3_CHICK Isoform 1 of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAG8/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQACLCALYLLSNPRTTST", "length": 1020, "header": "tr|A0A8V0YAG8-1|A0A8V0YGX3_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23472308, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030552.1", "url": "https://www.ensembl.org/id/ENSGALT00010030552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017724.1", "url": "https://www.ensembl.org/id/ENSGALP00010017724.1" } ] } }, { "isoform_ac": "A0A8V0YAI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAI9/entry", "sequence": { "sequence": "MLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1050, "header": "tr|A0A8V0YAI9-1|A0A8V0YGX3_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23488358, "end_pos": 23344947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030596.1", "url": "https://www.ensembl.org/id/ENSGALT00010030596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017750.1", "url": "https://www.ensembl.org/id/ENSGALP00010017750.1" } ] } }, { "isoform_ac": "A0A8V0YFU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU1/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHSLGRALHLVIVFLTNRILSASAGNN", "length": 1074, "header": "tr|A0A8V0YFU1-1|A0A8V0YFU1_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23484404, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030584.1", "url": "https://www.ensembl.org/id/ENSGALT00010030584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017744.1", "url": "https://www.ensembl.org/id/ENSGALP00010017744.1" } ] } }, { "isoform_ac": "A0A8V0YGV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV9/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1040, "header": "tr|A0A8V0YGV9-1|A0A8V0YGV9_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23488358, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030612.1", "url": "https://www.ensembl.org/id/ENSGALT00010030612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017757.1", "url": "https://www.ensembl.org/id/ENSGALP00010017757.1" } ] } }, { "isoform_ac": "A0A8V0YGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1100, "header": "tr|A0A8V0YGX3-1|A0A8V0YGX3_CHICK Isoform 1 of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23488358, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030656.1", "url": "https://www.ensembl.org/id/ENSGALT00010030656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017773.1", "url": "https://www.ensembl.org/id/ENSGALP00010017773.1" } ] } }, { "isoform_ac": "A0A8V0YIT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT4/entry", "sequence": { "sequence": "MNAVLLHIVGNFEVTLKPYISIEEKRLAADDPYEYMAQYFALNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQACLCALYLLSNPR", "length": 1014, "header": "tr|A0A8V0YIT4-1|A0A8V0YIT4_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23472092, "end_pos": 23340188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030543.1", "url": "https://www.ensembl.org/id/ENSGALT00010030543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017717.1", "url": "https://www.ensembl.org/id/ENSGALP00010017717.1" } ] } }, { "isoform_ac": "A0A8V0YIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV3/entry", "sequence": { "sequence": "MERNSTVLDKIVEVSCTIKSAFKVGNFEVTLKPYISIEEKRLAADDPYEYMAQYFALNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1113, "header": "tr|A0A8V0YIV3-1|A0A8V0YIV3_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23488358, "end_pos": 23340881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030571.1", "url": "https://www.ensembl.org/id/ENSGALT00010030571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017737.1", "url": "https://www.ensembl.org/id/ENSGALP00010017737.1" } ] } }, { "isoform_ac": "A0A8V0YIY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIY2/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQGMLTGMNETSATIDVAPQNSTSRVITERLMKAANLGVVPSGQDKIHRFAAKTVHSGSLMLVTVELKESSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1039, "header": "tr|A0A8V0YIY2-1|A0A8V0YIY2_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23488358, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030637.1", "url": "https://www.ensembl.org/id/ENSGALT00010030637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017768.1", "url": "https://www.ensembl.org/id/ENSGALP00010017768.1" } ] } }, { "isoform_ac": "A0A8V0YNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN1/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQEPRAHRRSVLGE", "length": 1015, "header": "tr|A0A8V0YNN1-1|A0A8V0YNN1_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23472330, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030560.1", "url": "https://www.ensembl.org/id/ENSGALT00010030560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017730.1", "url": "https://www.ensembl.org/id/ENSGALP00010017730.1" } ] } }, { "isoform_ac": "A0A8V0YNP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP5/entry", "sequence": { "sequence": "MSGNGIGYGEQGGEVAPELAQEAAPTTAPSVPAAFGLFSSDTKKNEDLKQMLESSKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLMRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASSDLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLRDRSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKTDEDVGDEYNENNFYESDEEQKEKDRKVKKTYTMDPDHRLLLRNTKPLLQSRNAAVVMAVAQLYWHLAPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEIMTNLANEANISTLLREFQTYVKSQDKQFAAATIQAIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQTQPAHHGEIIKHMAKLLDNITVPVARASILWLIGEYCERVPKIAPDVLRKTAKSFTNEDDLVKLQILNLGAKLYLTNSKQTKLLTQYVLNLGKYDQSYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNSRATGYLELSDWPEVAPDPAVRNVEVAESAKEWTAILSKTKKEKPTEKFYSESEEEEEDSASTSATESESGSESEKERKEESSSNESSESSSSTGVSSDSESEESTEKKTSGAAEESDSEDIKKKAKEISKSRSTFSSSDTESSSSEESSSNSKSESDSNNDSDTEKSRNATSSKKGEKTVQGRKAPNKQDVFLLDLDDFYPVTTPVAVPAAAILSPSLTADLEGLSLSGSPVIDVTTQVFVPTKMHEMLHRMTGKGLSAHYQFSRQPCIFGDRMVSVQVTLTNTSDQKIENIHIGEKKLPPGMRMHEFNPIECLEPERSVTVSMGIDFCDSTQTASFQLCTKDDHFNVNIQPPVGELLLPVTMSEKDFKKEQACLCALYLLSNPRDADRNE", "length": 1022, "header": "tr|A0A8V0YNP5-1|A0A8V0YNP5_CHICK Computationally mapped isoform of AP-3 complex subunit beta OS=Gallus gallus OX=9031 GN=AP3B1 PE=1 SV=1 CANONICAL=A0A8V0YGX3-1" }, "locus": { "chromosome": "Z", "start_pos": 23476166, "end_pos": 23329586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030590.1", "url": "https://www.ensembl.org/id/ENSGALT00010030590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017746.1", "url": "https://www.ensembl.org/id/ENSGALP00010017746.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427646", "resource": "KEGG Pathway" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIE5-1", "protein_name": "AP-3 complex subunit beta", "gene_name": "Ap3b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSNSFAYNEQSGGGEAAELGQEATSTISSSGAFGLFSSDWKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPVMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWREDDGVEDNEKNFYDSDDEEKKSGKKKPYSMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPRSEAGVISKSLVRLLRSHREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDKQFAAATIQTIGRCATSIAEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNVKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPLGKTKKEKPEKKFYSESEEEEEEEEEDEEDEEEDPSDSSSDSESGSGRESGDSGSSSEDSSEDSSSGQDSETGSEAEAEHQRVAKTNSKTKRKSASEDREKKNGKSQASESSSEESSSTEESSSESESGSDSEPAPRKTAKAKERKPQQERHPPSKDVFLLDLDDFNPVSTPVALPTPALSPSLIADLEGLNLSTSSSIINVSTPVFVPTKTHELLHRMRGKGLAAHYCFPRQPCIFGDKMVSVQITLTNTSDGKIENIHVGGKKLAVGVQMHVFHPIESLEPEGSVTVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQASQGMLTGMNETSATLIAAPQNFTPSMILQKVVNVANLGAVPSSQDNIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1099 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2G1-1", "protein_name": "AP-3 complex subunit beta", "gene_name": "AP3B1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSNSFAYNEQSGGGEATELGQEATSTISPSGAFGLFSSDMKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEIIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEDDGLEDNEKDFYDSDEEQKEKSDKRKKAYTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHIAPKSEVGIISKPLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKILKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATNISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPIQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPIIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSRQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNTKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTPAGKAKKEKPDKKFYSESEEEEDSSESSSDSESESGSESGEQDEEGDSSEDSSEDSSEHQSESGSESEAENKRAGQKSSRTKGKRDSEDVDKENENSKTSDSSDAESSSIEGSSSGSESESVSESESESRKVTKEKGKKPKQDGNPLTKDVSLLDLDDFNPVSTPVALPVPALSPSLIADLEGLNLSASSSVISVSTPVFVPMTTHVLLHRMSGKGLAAHYSFPRQPCIFGDKMVSVQITLNNTTDRKIENIHIGEKKLPMGMQMHVFNPIGSLEPGGSITVSMGIDFCDSTQTASLQLCTKDDCFSVNIQPPVGELLLPVAMSEKDFKKEQGRLTGMNETSTLIIAAPQNFTSSVILQKVVNVANLGVVPSGQDNVHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQGTPSTVEREELQKPLSRVWENRRYALFMCVPQETYSPAGNK", "length": 1130 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H316-1", "protein_name": "AP-3 complex subunit beta", "gene_name": "Ap3b1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSNSFAYNEQSGGGEAAELGQEATSTISPSGAFGLFSSDWKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWREDDGLEDNEKNFYESDDEEKEKSDKKRPYTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGVISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATSITEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKTFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPVGKSKKEKPAKKFYSESEEEEAEEEESSDSSSDSEGESGSESGDTGSSSEDSSEDSSSGQESETGSEAEAEGKRAGKRNSRLKRKSDSEDGEKKNEKSKTSESSSAESSSMEESSSGSESASESDNEPVPRKVAQAKERKPQQERHPPPKDVFLLDLDDFNPVSTPVALPTPALSPSLIADLEGLNLSTSSSVINVSTPVFVPTKTHELLHRMSGKGLAAWYCFPRQPCIFGDKMVSVQITLKNTSDRKIENIHIGEKKLPVGMQMHVFHPIDSLEPEGSVTVSVGIDFCDSTQTACFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKERGMLTGMNETSATVIAAPQNFTPSMILQKVVNVANLGAVPSGQDNVHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTLIGSVLLRELKPVLSQG", "length": 1091 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00203-1", "protein_name": "AP-3 complex subunit beta-1", "gene_name": "AP3B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSNSFPYNEQSGGGEATELGQEATSTISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEGDELEDNGKNFYESDDDQKEKTDKKKKPYTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNVKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDLDDFNPVSTPVALPTPALSPSLMADLEGLHLSTSSSVISVSTPAFVPTKTHVLLHRMSGKGLAAHYFFPRQPCIFGDKMVSIQITLNNTTDRKIENIHIGEKKLPIGMKMHVFNPIDSLEPEGSITVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQGVLTGMNETSAVIIAAPQNFTPSVIFQKVVNVANVGAVPSGQDNIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1094 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32PG1-1", "protein_name": "AP-3 complex subunit beta-1", "gene_name": "AP3B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSNSFAYNEQSGGGEATELGQEATSTISPSGAFGLFSSDMKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEIIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWRQGDVLEDNEKDFYDSDEEQKEKADKRKRPYAMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHIAPKSEAGIISKSLVRLLRSSREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDATMIKILKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATSITEVSDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPMQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKTAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNTKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTPAGKAKKENPDKKFYSESEEEEDSSESSSDSESESGSESGEDEEDDRSGDSAEDSGESGSEPEAGKGRAATRSRARGRGDSKDVDKEKENSKTSESSSGESSSIEESSSDSESESESESESESRKVTKEKEKKTKQERNPLTKDVSLLDLDDFNLVSTPVALPTPALSPSLIADLEGLNLSATSSVISVSTPVFVPGKTHVLLHRMSGKGLAAHYFFPRQPCIFGDKMVSVQITLNNTTDQKIENIHVGGKKLPMGMQMHVFNPIESLEPAGSITVSMGIDFCDSTQTASFQLCTKDDCFSVNIQPPVGELLLPVAMSEKDFKKEQGMLSGMNETSTTIIAAPQNFASSVILQKIVNVANVGVVPSGQDNIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1084 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Z1T1-1", "protein_name": "AP-3 complex subunit beta-1", "gene_name": "Ap3b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSNSFAYNEQSGGGEAAELGQEATSTISPSGAFGLFSSDWKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPVMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWREDGGLEDNEKNFYESEEEEEEKEKSSRKKSYAMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGVISKSLVRLLRSNREVQYIVLQNIATMSIERKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDKQFAAATIQTIGRCATSISEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIRHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLAAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNEKSGALSKYAKKIFLAPKPAPLLESPFKDRDRFQLGTLSHTLNIKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPLGKTKKEKPMKKFYSESEEEEDEDEDEDEEEEEKEDEDENPSDSSSDSESGSGSESGDTGTEDSSEDSSSGQDSETGSQAEAERQKVAKRNSKTKRKSDSENREKKNENSKASESSSEESSSMEDSSSESESESGSDSEPAPRNVAPAKERKPQQERHPPSKDVFLLDLDDFNPVSTPVALPTPALSPSLIADLEGLNLSTSSSVINVSTPVFVPTKTHELLHRMHGKGLAAHYCFPRQPCIFSDKMVSVQITLTNTSDRKIENIHIGGKGLPVGMQMHAFHPIDSLEPKGSVTVSVGIDFCDSTQTASFQLCTKDDCFNVTLQPPVGELLSPVAMSEKDFKKEQGTLTGMNETSATLIAAPQNFTPSMILQKVVNVANLGAVPSSQDNVHRFAARTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG", "length": 1105 }, "evidence": [ { "id": "A0A8V0YGX3", "url": "https://omabrowser.org/oma/group/A0A8V0YGX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX3" } ], "pmid": "" }, { "name": "melanosome organization", "id": "GO:0032438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032438", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX3", "url": 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:: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004937790.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937790" } ] }, { "annotation": "May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN3#function" }, { "database": "UniProtKB", "id": "PIRNR005856", "url": "https://www.uniprot.org/uniprotkb/PIRNR005856#function" }, { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18#function" } ] }, { "annotation": "Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18#function" }, { "database": "UniProtKB", "id": "ARBA00056818", "url": "https://www.uniprot.org/uniprotkb/ARBA00056818#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18", "locus": { "chromosome": "1", "start_pos": 50915920, "end_pos": 50901428, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012801", "url": "https://www.ensembl.org/id/ENSGALG00010012801" } ] } } ], "crossref": [ { "id": "A0A8V0YJ18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19514", "url": 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] }, { "id": "IPR020587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427903", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANPMKPV", "url": "https://omabrowser.org/oma/group/ANPMKPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAN3", "url": "https://www.orthodb.org/?gene=A0A8V0YAN3", "database": "OrthoDB", "categories": [ 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937790", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAMEDQVVQEESGYHDDEESFFQDIDLLQKHGINVADIKKLKSVGICTIKGVQMTTRRALCNVKGLSEVKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGPKGYTGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPVGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITPGGIGDAKE", "length": 342, "header": "tr|A0A8V0YJ18-1|A0A8V0YJ18_CHICK Isoform 1 of Meiotic recombination protein OS=Gallus gallus OX=9031 GN=DMC1 PE=3 SV=1 CANONICAL=A0A8V0YJ18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN3/entry", "sequence": { "sequence": "MKAMEDQVVQEESGYHDDEESFFQDIDLLQKHGINVADIKKLKSVGICTIKGVQMTTRRALCNVKGLSEVKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCGEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPVGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITPGGIGDAKE", "length": 287, "header": "tr|A0A8V0YAN3-1|A0A8V0YJ18_CHICK Computationally mapped isoform of Meiotic recombination protein OS=Gallus gallus OX=9031 GN=DMC1 PE=3 SV=1 CANONICAL=A0A8V0YJ18-1" }, "locus": { "chromosome": "1", "start_pos": 50915611, "end_pos": 50904351, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030707.1", "url": "https://www.ensembl.org/id/ENSGALT00010030707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017808.1", "url": "https://www.ensembl.org/id/ENSGALP00010017808.1" } ] } }, { "isoform_ac": "A0A8V0YJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18/entry", "sequence": { "sequence": "MKAMEDQVVQEESGYHDDEESFFQDIDLLQKHGINVADIKKLKSVGICTIKGVQMTTRRALCNVKGLSEVKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGPKGYTGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPVGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITPGGIGDAKE", "length": 342, "header": "tr|A0A8V0YJ18-1|A0A8V0YJ18_CHICK Isoform 1 of Meiotic recombination protein OS=Gallus gallus OX=9031 GN=DMC1 PE=3 SV=1 CANONICAL=A0A8V0YJ18-1" }, "locus": { "chromosome": "1", "start_pos": 50915611, "end_pos": 50904351, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030710.1", "url": "https://www.ensembl.org/id/ENSGALT00010030710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017811.1", "url": "https://www.ensembl.org/id/ENSGALP00010017811.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427903", "resource": "KEGG Pathway" }, { "id": "R-GGA-912446", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912446", "resource": "Reactome", "description": "Meiotic recombination" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJ85-1", "protein_name": "Meiotic recombination protein", "gene_name": "Dmc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEDQVVQEESGFQDEEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGDAKE", "length": 340 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N1D2-1", "protein_name": "Meiotic recombination protein", "gene_name": "DMC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKEDQVVLEEPGFQDEDESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHNAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "length": 340 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SKQ1-1", "protein_name": "Meiotic recombination protein", "gene_name": "DMC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKEDQVVLEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPVGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "length": 340 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P25453-1", "protein_name": "Meiotic recombination protein DMC1", "gene_name": "DMC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVTGTEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD", "length": 334 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14565-1", "protein_name": "Meiotic recombination protein DMC1 homolog", "gene_name": "DMC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "length": 340 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61880-1", "protein_name": "Meiotic recombination protein DMC1 homolog", "gene_name": "Dmc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE", "length": 340 }, "evidence": [ { "id": "A0A8V0YJ18", "url": "https://omabrowser.org/oma/group/A0A8V0YJ18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "DNA strand exchange activity", "id": "GO:0000150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "mitotic recombination", "id": "GO:0006312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006312", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "double-strand break repair involved in meiotic recombination", "id": "GO:1990918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990918", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "female gamete generation", "id": "GO:0007292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "DNA recombinase assembly", "id": "GO:0000730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "DNA strand invasion", "id": "GO:0042148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" }, { "name": "chromosome organization involved in meiotic cell cycle", "id": "GO:0070192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" }, { "id": "PS50162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 1", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 272, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ18" }, { "id": "PS50163", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50163" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 2", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 342, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 333 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"MTPRKKLEGLVAATVTPMTPDGRINLSVIHQYVDYLVSEQNVKNIFVNGTTGEGLSLSIQERKQLAEEWMCQGKDKLDHVIIHVGALSLLESQELARHAAAIGASGIAVIAPSFFKPTNKDELLGFLQKVASEAPTVPFYYYHIPAMTGVKIRVEELLDGIREQIPTFQGVKFSDTDLLDLAQCINKKEREQFVFLYGVDEQLLSALAIGANGAVGSTYNYLGRKTNLMLQAFAKPDLALARKYQVQYFCYPHREQTFFLLYLPWGVLCVVLSPVPSDIPVKVNCFQLQPPAFYS", "length": 295, "header": "tr|A0A8V0YAY7-1|A0A8V0YHW4_CHICK Computationally mapped isoform of N-acetylneuraminate lyase OS=Gallus gallus OX=9031 GN=NPL PE=3 SV=1 CANONICAL=A0A8V0YHW4-1" }, "locus": { "chromosome": "8", "start_pos": 7439259, "end_pos": 7432826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027354.1", "url": "https://www.ensembl.org/id/ENSGALT00010027354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015608.1", "url": "https://www.ensembl.org/id/ENSGALP00010015608.1" } ] } }, { "isoform_ac": "A0A8V0YD71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD71/entry", "sequence": { "sequence": "MTPRKKLEGLVAATVTPMTPDGRINLSVIHQYVDYLVSEQNVKNIFVNGTTGEGLSLSIQERKQLAEEWMCQGKDKLDHVIIHVGALSLLESQELARHAAAIGASGIAVIAPSFFKPTNKDELLGFLQKVASEAPTVPFYYYHIPAMTGVKIRVEELLDGIREQIPTFQGVKFSDTDLLDLAQCINKKEREQFVFLYGVDEQLLSALAIGANGAVGSTYNYLGRKTNLMLQAFAKPDLALARKYQTKAVMTSVSGIPMGPPRLPLVGASEEFIAKAKAKLESIVWPDGD", "length": 289, "header": "tr|A0A8V0YD71-1|A0A8V0YHW4_CHICK Computationally mapped isoform of N-acetylneuraminate lyase OS=Gallus gallus OX=9031 GN=NPL PE=3 SV=1 CANONICAL=A0A8V0YHW4-1" }, "locus": { "chromosome": "8", "start_pos": 7441544, "end_pos": 7432826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027356.1", "url": "https://www.ensembl.org/id/ENSGALT00010027356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015610.1", "url": "https://www.ensembl.org/id/ENSGALP00010015610.1" } ] } }, { "isoform_ac": "A0A8V0YD78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD78/entry", "sequence": { "sequence": "MTPRKKLEGLVAATVTPMTPDGRINLSVIHQYVDYLVSEQNVKNIFVNGTTGEGLSLSIQERKQLAEEWMCQGKDKLDHVIIHVGALSLLESQELARHAAAIGASGIAVIAPSFFKPTNKDELLGFLQKVASEAPTVPFYYYHIPAMTGVKIRVEELLDGIREQIPTFQGVKFSDTDLLDLAQCINKKEREQFVFLYGVDEQLLSALAIGANGAVGSTYNYLGRKTNLMLQAFAKPDLALARKYQFLTGEFLSFVIKLGFGVAQTKAVMTSVSGIPMGPPRLPLVGASEEFIAKAKAKLESIVWPDGD", "length": 308, "header": "tr|A0A8V0YD78-1|A0A8V0YHW4_CHICK Computationally mapped isoform of N-acetylneuraminate lyase OS=Gallus gallus OX=9031 GN=NPL PE=3 SV=1 CANONICAL=A0A8V0YHW4-1" }, "locus": { "chromosome": "8", "start_pos": 7441544, "end_pos": 7432826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027361.1", "url": "https://www.ensembl.org/id/ENSGALT00010027361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015615.1", "url": "https://www.ensembl.org/id/ENSGALP00010015615.1" } ] } }, { "isoform_ac": "A0A8V0YHW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4/entry", "sequence": { "sequence": "MTPRKKLEGLVAATVTPMTPDGRINLSVIHQYVDYLVSEQNVKNIFVNGTTGEGLSLSIQERKQLAEEWMCQGKDKLDHVIIHVGALSLLESQELARHAAAIGASGIAVIAPSFFKPTNKDELLGFLQKVASEAPTVPFYYYHIPAMTGVKIRVEELLDGIREQIPTFQGVKFSDTDLLDLAQCINKKEREQFVFLYGVDEQLLSALAIGANGAVGRESLLSSLYCTYNYLGRKTNLMLQAFAKPDLALARKYQFLTGEFLSFVIKLGFGVAQTKAVMTSVSGIPMGPPRLPLVGASEEFIAKAKAKLESIVWPDGD", "length": 317, "header": "tr|A0A8V0YHW4-1|A0A8V0YHW4_CHICK Isoform 1 of N-acetylneuraminate lyase OS=Gallus gallus OX=9031 GN=NPL PE=3 SV=1 CANONICAL=A0A8V0YHW4-1" }, "locus": { "chromosome": "8", "start_pos": 7441544, "end_pos": 7432826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027359.1", "url": "https://www.ensembl.org/id/ENSGALT00010027359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015613.1", "url": "https://www.ensembl.org/id/ENSGALP00010015613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:429074", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429074", "resource": "KEGG Pathway" }, { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "Q29RY9-1", "protein_name": "N-acetylneuraminate lyase", "gene_name": "NPL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASPKKKLQGLVAATITPMTEHGEINFSVIGRYVDYLVEEQGVKNVFVNGTTGEGLSLSISERCQVAEEWVTKGKNKLDQIVIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWNKDVLINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGIQDKIPSFQGLKFSDTDLLDFGQCVDQNRQRQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTKQMLEAFERKDFSSALNHQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDNAEAKLKSLDFLSCTDLKDGNMEACS", "length": 320 }, "evidence": [ { "id": "A0A8V0YHW4", "url": "https://omabrowser.org/oma/group/A0A8V0YHW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylneuraminate lyase activity", "id": "GO:0008747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008747", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "N-acetylneuraminate catabolic process", "id": "GO:0019262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23296", "name": "", "equation": "aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZKD4-1", "A0A8V0YHW4-1" ], "evidence": [ { "id": "23296", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23296" } ] }, { "id": "R-GGA-4085217", "name": "NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHW4-1" ], "evidence": [ { "id": "R-GGA-4085217", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085217" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YHW4", "gene_name": "NPL", "activity": [ { "ec_number": "4.1.3.3", "activity": "aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate.", "evidence": [ { "id": "A0A8V0YHW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ] }, { "ec_number": "4.1.3.3", "activity": "", "evidence": [ { "id": "A0A8V0YHW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW4" } ] } ] }, { "uniprot_ac": "Q5ZKD4", "gene_name": "NPL", "activity": [ { "ec_number": "4.1.3.3", "activity": "aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate.", "evidence": [ { "id": "Q5ZKD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD4" } ] }, { "ec_number": "4.1.3.3", "activity": "", "evidence": [ { "id": "Q5ZKD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.3.3", "ec_name": "aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate.", "evidence": [ { "id": "4.1.3.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.3" }, { "id": "4.1.3.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.3.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGA5-1", "uniprot_ac": "A0A8V0YGA5", "uniprot_id": "A0A8V0YGA5_CHICK", "mass": { "chemical_mass": 63874.0, "monoisotopic_mass": 63874.0 }, "refseq": {}, "gene_names": [ { "name": "HSF2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ] } ], "protein_names": [ { "name": "Heat shock transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YGA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5", "locus": { "chromosome": "3", "start_pos": 60968000, "end_pos": 60990044, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012875", "url": "https://www.ensembl.org/id/ENSGALG00010012875" } ] } } ], "crossref": [ { "id": "A0A8V0YGA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "421724", "url": "https://www.ncbi.nlm.nih.gov/gene/421724", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "423684", "url": "https://www.iedb.org/epitope/423684", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421724", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421724", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKQCGID", "url": "https://omabrowser.org/oma/group/GKQCGID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YAZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGA5", "url": "https://www.orthodb.org/?gene=A0A8V0YGA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJC8", "url": "https://www.orthodb.org/?gene=A0A8V0YJC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGAEWRWLPSSRAPPPVRRRRSRATMKQEPQQQQPAQQPPPAGAGVPAFLSKLWALVGEAPSNQLITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHVDSGIVKLERDGLVEFQHPYFKQGREDLLEHIKRKVSSSRPEENKISQEDLSKIISSAQKVEIKQETIESRLSALKRENESLWREVAELRAKHLKQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGPTKSNVFQQIVKEPADNNHVPLNRTEGLKQREQISDDIIIYDVTEDVADEENTMVDEENAPITPETNEDTTSDSSNCSRSPDIVIVEDDNEEEYAPVIQGDKSTESVAVSANDPLSPVSDSTSPLMSSAVQLNNQSTLTAEDPVSMMDSILNENGVISQNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLFDMETKGIETTKSNAGPAASQETQVSKPKSDKQLIQYTAFPLLAFLDGNPGSTVESGSSATETPSSVDKPLEVDELLESSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPMDTDMPFLDN", "length": 572, "header": "tr|A0A8V0YGA5-1|A0A8V0YGA5_CHICK Isoform 1 of Heat shock transcription factor 2 OS=Gallus gallus OX=9031 GN=HSF2 PE=3 SV=1 CANONICAL=A0A8V0YGA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ7/entry", "sequence": { "sequence": "MKQEPQQQQPAQQPPPAGAGVPAFLSKLWALVGEAPSNQLITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMCKFSYFVFILDLQKKIVSSSRPEENKISQEDLSKIISSAQKVEIKQETIESRLSALKRENESLWREVAELRAKHLKQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGPTKSNVFQQIVKEPADNNHVPLNRTEGLKQREQISDDIIIYDVTEDVADEENTMVDEENAPITPETNEDTTSDSSNCSRSPDIVIVEDDNEEEYAPVIQGDKSTESVAVSANDPLSPVSDSTSPLMSSAVQLNNQSTLTAEDPVSMMDSILNENGVISQNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLFDLFTSSVQMNPTDHIPNTKMETKGIETTKSNAGPAASQETQVSKPKSDKQLIQYTAFPLLAFLDGNPGSTVESGSSATETPSSVDKPLEVDELLESSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPMDTDMPFLDN", "length": 536, "header": "tr|A0A8V0YAZ7-1|A0A8V0YGA5_CHICK Computationally mapped isoform of Heat shock transcription factor 2 OS=Gallus gallus OX=9031 GN=HSF2 PE=3 SV=1 CANONICAL=A0A8V0YGA5-1" }, "locus": { "chromosome": "3", "start_pos": 60989956, "end_pos": 60969285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030898.1", "url": "https://www.ensembl.org/id/ENSGALT00010030898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017941.1", "url": "https://www.ensembl.org/id/ENSGALP00010017941.1" } ] } }, { "isoform_ac": "A0A8V0YGA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5/entry", "sequence": { "sequence": "MRGGAEWRWLPSSRAPPPVRRRRSRATMKQEPQQQQPAQQPPPAGAGVPAFLSKLWALVGEAPSNQLITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHVDSGIVKLERDGLVEFQHPYFKQGREDLLEHIKRKVSSSRPEENKISQEDLSKIISSAQKVEIKQETIESRLSALKRENESLWREVAELRAKHLKQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGPTKSNVFQQIVKEPADNNHVPLNRTEGLKQREQISDDIIIYDVTEDVADEENTMVDEENAPITPETNEDTTSDSSNCSRSPDIVIVEDDNEEEYAPVIQGDKSTESVAVSANDPLSPVSDSTSPLMSSAVQLNNQSTLTAEDPVSMMDSILNENGVISQNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLFDMETKGIETTKSNAGPAASQETQVSKPKSDKQLIQYTAFPLLAFLDGNPGSTVESGSSATETPSSVDKPLEVDELLESSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPMDTDMPFLDN", "length": 572, "header": "tr|A0A8V0YGA5-1|A0A8V0YGA5_CHICK Isoform 1 of Heat shock transcription factor 2 OS=Gallus gallus OX=9031 GN=HSF2 PE=3 SV=1 CANONICAL=A0A8V0YGA5-1" }, "locus": { "chromosome": "3", "start_pos": 60990037, "end_pos": 60969285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030891.1", "url": "https://www.ensembl.org/id/ENSGALT00010030891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017935.1", "url": "https://www.ensembl.org/id/ENSGALP00010017935.1" } ] } }, { "isoform_ac": "A0A8V0YJC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC8/entry", "sequence": { "sequence": "MKQEPQQQQPAQQPPPAGAGVPAFLSKLWALVGEAPSNQLITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHVDSGIVKLERDGLVEFQHPYFKQGREDLLEHIKRKVSSSRPEENKISQEDLSKIISSAQKVEIKQETIESRLSALKRENESLWREVAELRAKHLKQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGPTKSNVFQQIVKEPADNNHVPLNRTEGLKQREQISDDIIIYDVTEDVADEENTMVDEENAPITPETNEDTTSDSSNCSRSPDIVIVEDDNEEEYAPVIQGDKSTESVAVSANDPLSPVSDSTSPLMSSAVQLNNQSTLTAEDPVSMMDSILNENGVISQNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLFDLFTSSVQMNPTDHIPNTKMETKGIETTKSNAGPAASQETQVSKPKSDKQLIQYTAFPLLAFLDGNPGSTVESGSSATETPSSVDKPLEVDELLESSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPMDTDMPFLDN", "length": 563, "header": "tr|A0A8V0YJC8-1|A0A8V0YJC8_CHICK Computationally mapped isoform of Heat shock transcription factor 2 OS=Gallus gallus OX=9031 GN=HSF2 PE=3 SV=1 CANONICAL=A0A8V0YGA5-1" }, "locus": { "chromosome": "3", "start_pos": 60989956, "end_pos": 60969285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030895.1", "url": "https://www.ensembl.org/id/ENSGALT00010030895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017939.1", "url": "https://www.ensembl.org/id/ENSGALP00010017939.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421724", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421724", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L2J2-1", "protein_name": "Heat shock transcription factor 2", "gene_name": "Hsf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIESGIVKQERDGPVEFQHPHFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAPKKNLFQHIVKEPTDNHHHKVPHSRTEGLKSRERISDDIIIYDVTEDNVDEENIPVIPETNEDVVVDPSSQYPDIVIVEDDNEDEYAPVIQSGEQSEPARVGSASSSSPLMSSAVQLNGSSNLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLEATKNSVVQQVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASAVEQGTTTASSEVVPSVDKPIEVDELLDSNLDQEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS", "length": 531 }, "evidence": [ { "id": "A0A8V0YGA5", "url": "https://omabrowser.org/oma/group/A0A8V0YGA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SF56-1", "protein_name": "Heat shock transcription factor 2", "gene_name": "HSF2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPADNHHHKVPHSRSEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGDQSEPARESLSSGSDGTSPLMSSAIQLNGSSSLTTEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKSSVVQPVSEEGRKSKPKTDKQLIQYTAFPLLAFLDGNPASAVEQGNTASSEVMSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS", "length": 535 }, "evidence": [ { "id": "A0A8V0YGA5", "url": "https://omabrowser.org/oma/group/A0A8V0YGA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P38533-1", "protein_name": "Heat shock factor protein 2", "gene_name": "Hsf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIESGIIKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAPKKNLYQHIVKEPTDNHHHKVPHSRTEGLKSRERISDDIIIYDVTDDNVDEENIPVIPETNEDVVVDSSNQYPDIVIVEDDNEDEYAPVIQSGEQSEPAREPLRVGSAGSSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDNIKYTKSENKGLEATKSSVVQHVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNSASAIEQGSTTASSEVVPSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS", "length": 535 }, "evidence": [ { "id": "A0A8V0YGA5", "url": "https://omabrowser.org/oma/group/A0A8V0YGA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03933-1", "protein_name": "Heat shock factor protein 2", "gene_name": "HSF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS", "length": 536 }, "evidence": [ { "id": "A0A8V0YGA5", "url": "https://omabrowser.org/oma/group/A0A8V0YGA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding", "id": "GO:0001162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA5" }, { "id": "PS00434", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00434" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 114, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHI3-1", "uniprot_ac": "A0A8V0YHI3", "uniprot_id": "A0A8V0YHI3_CHICK", "mass": { "chemical_mass": 42313.0, "monoisotopic_mass": 42313.0 }, "refseq": {}, "gene_names": [ { "name": "NKAIN1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3" } ] } ], "protein_names": [ { "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NKAIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3", "locus": { "chromosome": "23", "start_pos": 913788, "end_pos": 934783, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012905", "url": "https://www.ensembl.org/id/ENSGALG00010012905" } ] } } ], "crossref": [ { "id": "A0A8V0YHI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB52", "url": "https://www.orthodb.org/?gene=A0A8V0YB52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH5", "url": "https://www.orthodb.org/?gene=A0A8V0YGH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGI1", "url": "https://www.orthodb.org/?gene=A0A8V0YGI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHI3", "url": "https://www.orthodb.org/?gene=A0A8V0YHI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13084", "url": 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] }, { "id": "A0A8V0YGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPYSARWSCSSRDGVEAAPGAAGARGGDSGRCELCLQLRALRSEGGLQGCCSGSPASAAVTAKLGAAAALCKLRTERHRSAGRQRESGVWYDGAVGIGNNRVPRFRRPRIHLHHAADRGPGEGSAFRSNRQPARLQLIIQALPRFVKPCGQAAPLDVPRQQRQRWAQRESPECCRDVPVALGCPSARGCVGEIAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTIQYRSKYLIMYAVWLVLWVGWNAFIICFYLEVGHLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVITVSGCLLDYQYIEVLSSAAQIFLALFGFVYACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG", "length": 382, "header": "tr|A0A8V0YHI3-1|A0A8V0YHI3_CHICK Isoform 1 of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Gallus gallus OX=9031 GN=NKAIN1 PE=3 SV=2 CANONICAL=A0A8V0YHI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB52/entry", "sequence": { "sequence": "MGRCNGRCTLVGFCCLQLIAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTIQYRSKYLIMYAVWLVLWVGWNAFIICFYLEVGHLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVITVSGCLLDYQYIEVLSSAAQIFLALFGFVYACYVSKVFLFLRLGFQFEQRVLFL", "length": 187, "header": "tr|A0A8V0YB52-1|A0A8V0YHI3_CHICK Computationally mapped isoform of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Gallus gallus OX=9031 GN=NKAIN1 PE=3 SV=1 CANONICAL=A0A8V0YHI3-1" }, "locus": { "chromosome": "23", "start_pos": 934310, "end_pos": 915208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030978.1", "url": "https://www.ensembl.org/id/ENSGALT00010030978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018001.1", "url": "https://www.ensembl.org/id/ENSGALP00010018001.1" } ] } }, { "isoform_ac": "A0A8V0YGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH5/entry", "sequence": { "sequence": "MGRCNGRCTLVGFCCLQLIAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTIQYRSKYLIMYAVWLVLWVGWNAFIICFYLEVGHLSQVTTGFHSTARHCCLLAFLSLSSLNPSFPFLPFPSLLSLSIPLHPSLSISSVPSYPFHNNLSIPFLHPVPSLPSHLAPSHSILPFSSIPSLLFYPILSLPSSSLPPHPFKIQFLPPKPFIPSLLSISIPSISPLSFFLPYPNLSIPSNSVPPHPSHPFNSFLPHPIPFLSSHPYSSHAFYSTLFHPSHPFLLFHPIPLHPMSSVPSHPIPSFPLLPSFPFHPFPLISSFPVSFLLFHSIHPHPFLGM", "length": 337, "header": "tr|A0A8V0YGH5-1|A0A8V0YGH5_CHICK Computationally mapped isoform of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Gallus gallus OX=9031 GN=NKAIN1 PE=3 SV=1 CANONICAL=A0A8V0YHI3-1" }, "locus": { "chromosome": "23", "start_pos": 934310, "end_pos": 919599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030971.1", "url": "https://www.ensembl.org/id/ENSGALT00010030971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017995.1", "url": "https://www.ensembl.org/id/ENSGALP00010017995.1" } ] } }, { "isoform_ac": "A0A8V0YGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI1/entry", "sequence": { "sequence": "MDGEDAGGDGAGKKVAGLESGAWPCCPPEAPRAAAEEPEEGDAQPRRGDPRLRLGNHGEMQREMHAGWILLPAAAPLDVPRQQRQRWAQRESPECCRDVPVALGCPSARGCVGEVRALRSRSFRIKAMGVSLCAGLPRLSATLFFSIGQLKRSLAGVVLQGNIAALYREVIRIAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTIQYRSKYLIMYAVWLVLWVGWNAFIICFYLEVGHLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVITVSGCLLDYQYIEVLSSAAQIFLALFGFVYACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG", "length": 361, "header": "tr|A0A8V0YGI1-1|A0A8V0YGI1_CHICK Computationally mapped isoform of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Gallus gallus OX=9031 GN=NKAIN1 PE=3 SV=1 CANONICAL=A0A8V0YHI3-1" }, "locus": { "chromosome": "23", "start_pos": 934620, "end_pos": 915639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030976.1", "url": "https://www.ensembl.org/id/ENSGALT00010030976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018000.1", "url": "https://www.ensembl.org/id/ENSGALP00010018000.1" } ] } }, { "isoform_ac": "A0A8V0YHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3/entry", "sequence": { "sequence": "MLPYSARWSCSSRDGVEAAPGAAGARGGDSGRCELCLQLRALRSEGGLQGCCSGSPASAAVTAKLGAAAALCKLRTERHRSAGRQRESGVWYDGAVGIGNNRVPRFRRPRIHLHHAADRGPGEGSAFRSNRQPARLQLIIQALPRFVKPCGQAAPLDVPRQQRQRWAQRESPECCRDVPVALGCPSARGCVGEIAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTIQYRSKYLIMYAVWLVLWVGWNAFIICFYLEVGHLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVITVSGCLLDYQYIEVLSSAAQIFLALFGFVYACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG", "length": 382, "header": "tr|A0A8V0YHI3-1|A0A8V0YHI3_CHICK Isoform 1 of Sodium/potassium-transporting ATPase subunit beta-1-interacting protein OS=Gallus gallus OX=9031 GN=NKAIN1 PE=3 SV=2 CANONICAL=A0A8V0YHI3-1" }, "locus": { "chromosome": "23", "start_pos": 934105, "end_pos": 915639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030974.1", "url": "https://www.ensembl.org/id/ENSGALT00010030974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017998.1", "url": "https://www.ensembl.org/id/ENSGALP00010017998.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of sodium ion transport", "id": "GO:0002028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHJ7-1", "uniprot_ac": "A0A8V0YHJ7", "uniprot_id": "A0A8V0YHJ7_CHICK", "mass": { "chemical_mass": 90325.0, "monoisotopic_mass": 90325.0 }, "refseq": {}, "gene_names": [ { "name": "SELP", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ] } ], "protein_names": [ { "name": "p-selectin", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry#names_and_taxonomy" } ] }, { "name": "CD62 antigen-like family member P", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry#names_and_taxonomy" } ] }, { "name": "Granule membrane protein 140", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry#names_and_taxonomy" } ] }, { "name": "Leukocyte-endothelial cell adhesion molecule 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry#names_and_taxonomy" } ] }, { "name": "Platelet activation dependent granule-external membrane protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB73#function" }, { "database": "UniProtKB", "id": "ARBA00045502", "url": "https://www.uniprot.org/uniprotkb/ARBA00045502#function" }, { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7#function" }, { "database": "UniProtKB", "id": "A0A8V0YHK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK8#function" }, { "database": "UniProtKB", "id": "A0A8V0YJJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": 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}, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB58", "url": "https://www.orthodb.org/?gene=A0A8V0YB58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB73", "url": "https://www.orthodb.org/?gene=A0A8V0YB73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK8", "url": "https://www.orthodb.org/?gene=A0A8V0YHK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YJJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YB58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPVGQHCARRMWALSSCGVCCLGIAAFTCGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAISCSVLRAPEHGELNCSHLHGNFTFGSTCNLSCQPGFELLGPQSRECMPTRAWTGETSRCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEEDSAFLKQVLVYTSTSALAAAGLVLSGTLIVLLVKQLSNRGTKTPAANGRFVARDSQPRWLQGPKDSGLIKRV", "length": 824, "header": "tr|A0A8V0YHJ7-1|A0A8V0YHJ7_CHICK Isoform 1 of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB58/entry", "sequence": { "sequence": "MQSSAALWASSGSGMQYGTRTLLGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAISCSVLRAPEHGELNCSHLHGNFTFGSTCNLSCQPGFELLGPQSRECMPTRAWTGETSRCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEEDSAFLKQVLVYTSTSALAAAGLVLSGTLIVLLVKQLSNREEKKKLLSPTSDLGAPGIFTNAAYDSTL", "length": 811, "header": "tr|A0A8V0YB58-1|A0A8V0YHJ7_CHICK Computationally mapped isoform of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "locus": { "chromosome": "8", "start_pos": 3719848, "end_pos": 3713104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030988.1", "url": "https://www.ensembl.org/id/ENSGALT00010030988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018007.1", "url": "https://www.ensembl.org/id/ENSGALP00010018007.1" } ] } }, { "isoform_ac": "A0A8V0YB73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB73/entry", "sequence": { "sequence": "MGTPVGQHCARRMWALSSCGVCCLGIAAFTCGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAISCSVLRAPEHGELNCSHLHGNFTFGSTCNLSCQPGFELLGPQSRECMPTRAWTGETSRCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEEDSAFLKQVLVYTSTSALAAAGLVLSGTLIVLLVKQLSNREEKKKLLSPTSDLGAPGIFTNAAYDSTL", "length": 819, "header": "tr|A0A8V0YB73-1|A0A8V0YHJ7_CHICK Computationally mapped isoform of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "locus": { "chromosome": "8", "start_pos": 3719848, "end_pos": 3711552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031011.1", "url": "https://www.ensembl.org/id/ENSGALT00010031011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018022.1", "url": "https://www.ensembl.org/id/ENSGALP00010018022.1" } ] } }, { "isoform_ac": "A0A8V0YHJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7/entry", "sequence": { "sequence": "MGTPVGQHCARRMWALSSCGVCCLGIAAFTCGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAISCSVLRAPEHGELNCSHLHGNFTFGSTCNLSCQPGFELLGPQSRECMPTRAWTGETSRCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEEDSAFLKQVLVYTSTSALAAAGLVLSGTLIVLLVKQLSNRGTKTPAANGRFVARDSQPRWLQGPKDSGLIKRV", "length": 824, "header": "tr|A0A8V0YHJ7-1|A0A8V0YHJ7_CHICK Isoform 1 of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "locus": { "chromosome": "8", "start_pos": 3719181, "end_pos": 3711552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030998.1", "url": "https://www.ensembl.org/id/ENSGALT00010030998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018014.1", "url": "https://www.ensembl.org/id/ENSGALP00010018014.1" } ] } }, { "isoform_ac": "A0A8V0YHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK8/entry", "sequence": { "sequence": "MGTPVGQHCARRMWALSSCGVCCLGIAAFTCGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEEDSAFLKQVLVYTSTSALAAAGLVLSGTLIVLLVKQLSNREEKKKLLSPTSDLGAPGIFTNAAYDSTL", "length": 757, "header": "tr|A0A8V0YHK8-1|A0A8V0YHK8_CHICK Computationally mapped isoform of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "locus": { "chromosome": "8", "start_pos": 3719848, "end_pos": 3711552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031013.1", "url": "https://www.ensembl.org/id/ENSGALT00010031013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018024.1", "url": "https://www.ensembl.org/id/ENSGALP00010018024.1" } ] } }, { "isoform_ac": "A0A8V0YJJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ2/entry", "sequence": { "sequence": "MGTPVGQHCARRMWALSSCGVCCLGIAAFTCGVVMQVGAWTYNYSEKDYEWDEARAYCKTFFTDLVAIQNKEEIEYLNRTLPYHNKYYWIGIRKQKGTWTWVGTNKTLTKEATNWAAREPNNRGSNQDCVEIYIKRPSEAGKWNDEPCTKKKKALCYKASCQPLLCGLHGDCVEVIQSYKCECHPGFEGDNCENAVQCPILEPRGASMNCSHPFGDFRYNSTCTFRCPEGFERRGADELQCLDDRQWSAETPTCIAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGNWTGEIPRCKAISCPVLSAPEHGELNCSHLHGSFTFNSTCDFSCQPGFELVGSQSRECTATGNWTGDTSRCKAVTCPVLSAPEHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAMGNWTGDTTQCKAISCSVLRAPEHGELNCSHLHGNFTFGSTCNLSCQPGFELLGPQSRECMPTRAWTGETSRCKAVTCPVLSAPKHGELNCSHLHGNFTFNSTCDFSCQPGFELTGPQSRECTAVGTWSKDTPRCKAVTCPVLSAPEHGELNCSHLHENFTFGSTCDFSCQPGFELLGSQSRECTATRTWTRESPQCKAISCSLLSAPEHGELSCFHLYENFTFGSVCDFSCQPGFELIGPQSRECTATGTWTGNTSQCQAVSCPVLDVPSHGHLSCSNLHGNFTFNSTCTFSCKEGFIRVGAEMLRCAATGNWTRHPPVCEGMVGLCFPASYSISRGWRRHPAALSLWNPSDNKLFVGLFQRILPF", "length": 796, "header": "tr|A0A8V0YJJ2-1|A0A8V0YJJ2_CHICK Computationally mapped isoform of p-selectin OS=Gallus gallus OX=9031 GN=SELP PE=1 SV=1 CANONICAL=A0A8V0YHJ7-1" }, "locus": { "chromosome": "8", "start_pos": 3718978, "end_pos": 3711552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030991.1", "url": "https://www.ensembl.org/id/ENSGALT00010030991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018010.1", "url": "https://www.ensembl.org/id/ENSGALP00010018010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "leukocyte tethering or rolling", "id": "GO:0050901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "oligosaccharide binding", "id": "GO:0070492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" }, { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB83#function" }, { "database": "HAMAP", "id": "MF_03179", "url": "https://hamap.expasy.org/signature/MF_03179" }, { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8#function" }, { "database": "UniProtKB", "id": "A0A8V0YJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM3#function" }, { "database": "UniProtKB", "id": "A0A8V0YPG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSGEPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8", "locus": { "chromosome": "7", "start_pos": 405929, "end_pos": 393027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012926", "url": "https://www.ensembl.org/id/ENSGALG00010012926" } ] } } ], "crossref": [ { "id": "A0A8V0YJL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd24134", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24134", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423982", "url": "https://www.ncbi.nlm.nih.gov/gene/423982", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NAAMIGC", "url": "https://omabrowser.org/oma/group/NAAMIGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB83", "url": "https://www.orthodb.org/?gene=A0A8V0YB83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJL8", "url": "https://www.orthodb.org/?gene=A0A8V0YJL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJM3", "url": "https://www.orthodb.org/?gene=A0A8V0YJM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPG8", "url": "https://www.orthodb.org/?gene=A0A8V0YPG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11735:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11735:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "37059", "url": "https://www.rhea-db.org/rhea/37059", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YB83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSTALRFLQPVRHSMAAGLSGPPRHVRPPRLVLGIETSCDDTGAAVLDEAGTVLGEALQSQKEVHLKAGGIIPHVAQQLHRESIQQVVKEALSASGVSVNELAAIATTVKPGLALSLEVGLQYSLQLVDRYQKPFIPIHHMEAHALTIRLTEQVEFPFLVLLLSGGHCILAVARGVSDFLLLGQSIDIAPGDMLDKVARRLSLVKHPECHSMAGGKAIEHLAQTGDWQQYTFRLPMQQYRNCDFSFSGLQSLVNKAILQKEKEEGIQEGEILSCVKDIAAAAQHVVAAHIIQRTHRAMLFCMKNSILLPNTATLVVSGGVASNQYIRKGLQTLANANGFAFLSPPPRLCTDNGVMIAWNGIERLRAGCGILYSTDGIRYEPKAPLGIDISKRVEEDSIKVPRLRKIQWC", "length": 410, "header": "tr|A0A8V0YJL8-1|A0A8V0YJL8_CHICK Isoform 1 of N(6)-L-threonylcarbamoyladenine synthase OS=Gallus gallus OX=9031 GN=OSGEPL1 PE=3 SV=1 CANONICAL=A0A8V0YJL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB83/entry", "sequence": { "sequence": "MGSTALRFLQPVRHSMAAGLSGPPRHVRPPRLVLGIETSCDDTGAAVLDEAGTVLGEALQSQKEVHLKAGGIIPHVAQQLHRESIQQVVKEALSASGVSVNELAAIATTVKPGLALSLEVGLQYSLQLVDRYQKPFIPIHHMEAHALTIRLTEQVEFPFLVLLLSGGHCILAVARGVSDFLLLGQSIDIAPGDMLDKVARRLSLVKHPECHSMAGGKAIEHLAQTGDWQQYTFRLPMQQYRNCDFSFSGLQSLVNKAILQKEKEEGEILSCVKDIAAAAQHVVAAHIIQRTHRAMLFCMKNSILLPNTATLVVSGGVASNQYIRKGLQTLANANGFAFLSPPPRLCTDNGVMIAWNGIERLRAGCGILYSTDGIRYEPKAPLGIDISKRVEEDSIKVPRLRKIQWSAC", "length": 408, "header": "tr|A0A8V0YB83-1|A0A8V0YJL8_CHICK Computationally mapped isoform of N(6)-L-threonylcarbamoyladenine synthase OS=Gallus gallus OX=9031 GN=OSGEPL1 PE=3 SV=1 CANONICAL=A0A8V0YJL8-1" }, "locus": { "chromosome": "7", "start_pos": 400185, "end_pos": 394887, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031021.1", "url": "https://www.ensembl.org/id/ENSGALT00010031021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018032.1", "url": "https://www.ensembl.org/id/ENSGALP00010018032.1" } ] } }, { "isoform_ac": "A0A8V0YJL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8/entry", "sequence": { "sequence": "MGSTALRFLQPVRHSMAAGLSGPPRHVRPPRLVLGIETSCDDTGAAVLDEAGTVLGEALQSQKEVHLKAGGIIPHVAQQLHRESIQQVVKEALSASGVSVNELAAIATTVKPGLALSLEVGLQYSLQLVDRYQKPFIPIHHMEAHALTIRLTEQVEFPFLVLLLSGGHCILAVARGVSDFLLLGQSIDIAPGDMLDKVARRLSLVKHPECHSMAGGKAIEHLAQTGDWQQYTFRLPMQQYRNCDFSFSGLQSLVNKAILQKEKEEGIQEGEILSCVKDIAAAAQHVVAAHIIQRTHRAMLFCMKNSILLPNTATLVVSGGVASNQYIRKGLQTLANANGFAFLSPPPRLCTDNGVMIAWNGIERLRAGCGILYSTDGIRYEPKAPLGIDISKRVEEDSIKVPRLRKIQWC", "length": 410, "header": "tr|A0A8V0YJL8-1|A0A8V0YJL8_CHICK Isoform 1 of N(6)-L-threonylcarbamoyladenine synthase OS=Gallus gallus OX=9031 GN=OSGEPL1 PE=3 SV=1 CANONICAL=A0A8V0YJL8-1" }, "locus": { "chromosome": "7", "start_pos": 400281, "end_pos": 394887, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031028.1", "url": "https://www.ensembl.org/id/ENSGALT00010031028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018035.1", "url": "https://www.ensembl.org/id/ENSGALP00010018035.1" } ] } }, { "isoform_ac": "A0A8V0YJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM3/entry", "sequence": { "sequence": "MAPPPPNSGNVTSGVCPAPRPAGRLRLGLWSGGGRAAPGGYCAAPPLQAFTHQVSGSRTAQGTRGAPFQASPRAQLLPMGSTALRFLQPVRHSMAAGLSGPPRHVRPPRLVLGIETSCDDTGAAVLDEAGTVLGEALQSQKEVHLKAGGIIPHVAQQLHRESIQQVVKEALSASGVSVNELAAIATTVKPGLALSLEVGLQYSLQLVDRYQKPFIPIHHMEAHALTIRLTEQVEFPFLVLLLSGGHCILAVARGVSDFLLLGQSIDIAPGDMLDKVARRLSLVKHPECHSMAGGKAIEHLAQTGDWQQYTFRLPMQQYRNCDFSFSGLQSLVNKAILQKEKEEGIQEGEILSCVKDIAAAAQHVVAAHIIQRTHRAMLFCMKNSILLPNTATLVVSGGVASNQYIRKGLQTLANANGFAFLSPPPRLCTDNGVMIAWNGIERLRAGCGILYSTDGIRYEPKAPLGIDISKRVEEDSIKVPRLRKIQ", "length": 486, "header": "tr|A0A8V0YJM3-1|A0A8V0YJM3_CHICK Computationally mapped isoform of N(6)-L-threonylcarbamoyladenine synthase OS=Gallus gallus OX=9031 GN=OSGEPL1 PE=3 SV=1 CANONICAL=A0A8V0YJL8-1" }, "locus": { "chromosome": "7", "start_pos": 400175, "end_pos": 394306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031034.1", "url": "https://www.ensembl.org/id/ENSGALT00010031034.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018040.1", "url": "https://www.ensembl.org/id/ENSGALP00010018040.1" } ] } }, { "isoform_ac": "A0A8V0YPG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG8/entry", "sequence": { "sequence": "MAPPPPNSGNVTSGVCPAPRPAGRLRLGLWSGGGRAAPGGYCAAPPLQAFTHQVSGSRTAQGTRGAPFQASPRAQLLPMGSTALRFLQPVRHSMAAGLSGPPRHVRPPRLVLGIETSCDDTGAAVLDEAGTVLGEALQSQKEVHLKAGGIIPHVAQQLHRESIQQVVKEALSASGVSVNELAAIATTVKPGLALSLEVGLQYSLQLVDRYQKPFIPIHHMEAHALTIRLTEQVEFPFLVLLLSGGHCILAVARGVSDFLLLGQSIDIAPGDMLDKVARRLSLVKHPECHSMAGGKAIEHLAQTGDWQQYTFRLPMQQYRNCDFSFSGLQSLVNKAILQKEKEEGIQEGEILSCVKDIAAAAQHVVAAHIIQRTHRAMLFCMKNSILLPNTATLVVSGGVASNQYIRKGLQTLANANGFAFLSPPPRLCTDNGVMIAWNGIERLRAGCGILYSTDGIRYEPKDLP", "length": 464, "header": "tr|A0A8V0YPG8-1|A0A8V0YPG8_CHICK Computationally mapped isoform of N(6)-L-threonylcarbamoyladenine synthase OS=Gallus gallus OX=9031 GN=OSGEPL1 PE=3 SV=1 CANONICAL=A0A8V0YJL8-1" }, "locus": { "chromosome": "7", "start_pos": 405271, "end_pos": 394306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031039.1", "url": "https://www.ensembl.org/id/ENSGALT00010031039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018043.1", "url": "https://www.ensembl.org/id/ENSGALP00010018043.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B3M8-1", "protein_name": "N(6)-L-threonylcarbamoyladenine synthase", "gene_name": "OSGEPL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLILNKTTGVFSNLSKGKNYEFLRSFNIQPGKLFLHKLVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIIPPVAQQLHRENIQRIVQEALSASKVSPSELSAVATTVKPGLALSLGVGLFFSLQLVDQFKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALVRGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLSKQGNKLHFDFKPPMQRAKNCDFSFSGLQHVIDKTIMQKEKEEGIEKGQILSSAADIAAAVQHTVACHIAKRTHRAILFCKQRDLLCQSNAVLVVSGGVASNLYIRKALEVVTNATQCTLLCPPPRLCTDNGIMIAWNGVERLHAGLGILYNTEGIRYEPKCPLGIDISKEVGEAAIKVPRLKMKP", "length": 414 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O22145-1", "protein_name": "Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "GCP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVRLFLTLSPAISRFNLYPGISILARNNNSLRLQKHHKLKTKTPTFSLISPSSSPNFQRTRFYSTETRISSLPYSENPNFDDNLVVLGIETSCDDTAAAVVRGNGEILSQVISSQAELLVQYGGVAPKQAEEAHSRVIDKVVQDALDKANLTEKDLSAVAVTIGPGLSLCLRVGVRKARRVAGNFSLPIVGVHHMEAHALVARLVEQELSFPFMALLISGGHNLLVLAHKLGQYTQLGTTVDDAIGEAFDKTAKWLGLDMHRSGGPAVEELALEGDAKSVKFNVPMKYHKDCNFSYAGLKTQVRLAIEAKEIDAKCPVSSATNEDRRNRADIAASFQRVAVLHLEEKCERAIDWALELEPSIKHMVISGGVASNKYVRLRLNNIVENKNLKLVCPPPSLCTDNGVMVAWTGLEHFRVGRYDPPPPATEPEDYVYDLRPRWPLGEEYAKGRSEARSMRTARIHPSLTSIIRADSLQQQTQT", "length": 480 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P43122-1", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "QRI7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQL", "length": 407 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q4V7F3-1", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "Osgepl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLMLSKTAGAIPRPPRSNVRGFIRRFNVQPRALFHHKLVLGIETSCDDTAAAVVDETGNVLGEALHSQTEVHLKTGGIVPPVAQQLHRENIQRIVEEALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSVQLVNQFKKPFIPIHHMEAHALTIRLTHKVGFPFLVLLISGGHCLLALVQSVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKEGNRFHFTINPPMQNAKNCDFSFTGLQHVTDKLITHKEKEEGIEKGQILSSAADIAAAVQHATACHLAKRTHRAILFCQQKNLLSPANAVLVVSGGVASNLYIRRALEIVANATQCTLLCPPPRLCTDNGIMIAWNGIERLRAGLGILHDVEDIRYEPKCPLGIDISREVAEAAIKVPRLKMTL", "length": 414 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54EW4-1", "protein_name": "N(6)-L-threonylcarbamoyladenine synthase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSGSGLNNNNINNKKIFNVIGIETSCDDTSIGIVNSEGKIMAEYSKPQWSLHKVHNGIVPSIAFEAHQNEIDNAIEKTLDKAGMTMEDIDVIAVTTGPGMGKSLEVGLNKAKQLYREFKKPFCSVNHMEGHSLVVRMENHSIEFPFLIVLVSGGHSQILICNDVSKYQLIGNTLDDSIGEALDKAARILGCPYGQVWDGQSLIENIHGGQAIEILASKGDPNSHHFTLPMKDSNNCDFSFSGIKSSLARLVKEIKSKSSSSSSITNNTTTKTTTTTTTTTIITTETNNLITDENELSFVDKCNLAASFQNVAFNHLEHRIKKSLDWYYNFKTPKQKKNELLASKTKSGKPPAIEIIKREPLKGIVVSGGVSKNNNLRKRIDDIGKRYNLPIYFPRPELCNDNGTMIAWAGVEMFKKGMTVDDPEKVIYLPVWPLDLNPKQIFKSNLKEKDKQIRKGWYDNTIKKYGIQ", "length": 468 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6PEB4-1", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "Osgepl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLMLRRTAGAIPKPPKSKVYGFLRRFSVHPRTLSCHKLVLGIETSCDDTGAAVVDETGNVLGEALHSQTQVHLKTGGIVPPVAQQLHRENIQRIVEETLSACRITPSDLSAIATTIKPGLALSLGVGLSFSLQLVNQFKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEQLAKDGNRFHFTINPPMQNAKNCDFSFTGLQHITDKLITHKEKEEGIEKGQILSSAADIAAAVQHATACHLAKRTHRAILFCKQKNLLSPANAVLVVSGGVASNLYIRKALEIVANATQCTLLCPPPRLCTDNGIMIAWNGIERLRAGLGVLHDVEDIRYEPKCPLGVDISREVAEAAIKVPRLKMAL", "length": 414 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4B0-1", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "OSGEPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIKPPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNGIMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI", "length": 414 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWD6-1", "protein_name": "Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial", "gene_name": "Tcs4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHALRNFAGNGIANVFGCGIRRRLSYVLGIETSCDDTGIAIVDTTGRVIANVLESQQEFHTRYGGIIPPRAQDLHRARIESAYQRCMEAAQLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARMEHPEQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEYRLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRNCNFSFAGIKNNSFRAIRARERAERTPPDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDAIYANIEHLAAQYGCRSFRPSKRYCSDNGVMIAWHGVEQLLQDKEASTRYDYDSIDIQGSAGFAESHEEAVAAAAIKCKWIQPLV", "length": 409 }, "evidence": [ { "id": "A0A8V0YJL8", "url": "https://omabrowser.org/oma/group/A0A8V0YJL8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ], "pmid": "" }, { "name": "tRNA N(6)-L-threonylcarbamoyladenine synthase activity", "id": "GO:0061711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "37059", "name": "", "equation": "L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJL8-1" ], "evidence": [ { "id": "37059", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37059" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJL8", "gene_name": "OSGEPL1", "activity": [ { "ec_number": "2.3.1.234", "activity": "L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+).", "evidence": [ { "id": "A0A8V0YJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ] }, { "ec_number": "2.3.1.234", "activity": "", "evidence": [ { "id": "A0A8V0YJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL8" }, { "id": "PF00814", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00814" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gcp-like", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 359, "start_aa": "Thr", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.234", "ec_name": "L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+).", "evidence": [ { "id": "2.3.1.234", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.234" }, { "id": "2.3.1.234", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.234" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHT7-1", "uniprot_ac": "A0A8V0YHT7", "uniprot_id": "A0A8V0YHT7_CHICK", "mass": { "chemical_mass": 35026.0, "monoisotopic_mass": 35026.0 }, "refseq": {}, "gene_names": [ { "name": "DERA", "type": "recommended", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ], "protein_names": [ { "name": "Deoxyribose-phosphate aldolase", "type": "recommended", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7/entry#names_and_taxonomy" } ] }, { "name": "2-deoxy-D-ribose 5-phosphate aldolase", "type": "synonym", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7/entry#names_and_taxonomy" } ] }, { "name": "4.1.2.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7/entry#names_and_taxonomy" } ] }, { "name": "Phosphodeoxyriboaldolase", "type": "synonym", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT6#function" }, { "database": "UniProtKB", "id": "ARBA00054733", "url": "https://www.uniprot.org/uniprotkb/ARBA00054733#function" }, { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7#function" }, { "database": "UniProtKB", "id": "A0A8V0YJT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT9#function" }, { "database": "UniProtKB", "id": "A0A8V0YBE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE2#function" }, { "database": "UniProtKB", "id": "A0A8V0YGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU8#function" }, { "database": "UniProtKB", "id": "A0A8V0YPL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DERA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7", "locus": { "chromosome": "1", "start_pos": 63223380, "end_pos": 63168588, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012957", "url": "https://www.ensembl.org/id/ENSGALG00010012957" } ] } } ], "crossref": [ { "id": "A0A8V0YHT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00959", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00959", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418176", "url": "https://www.ncbi.nlm.nih.gov/gene/418176", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBE2", "url": "https://www.orthodb.org/?gene=A0A8V0YBE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGT6", "url": "https://www.orthodb.org/?gene=A0A8V0YGT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGU8", "url": "https://www.orthodb.org/?gene=A0A8V0YGU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHT7", "url": "https://www.orthodb.org/?gene=A0A8V0YHT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJT9", "url": "https://www.orthodb.org/?gene=A0A8V0YJT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPL3", "url": "https://www.orthodb.org/?gene=A0A8V0YPL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10889:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10889:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12821", "url": "https://www.rhea-db.org/rhea/12821", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARNAGTELETELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 320, "header": "tr|A0A8V0YHT7-1|A0A8V0YHT7_CHICK Isoform 1 of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE2/entry", "sequence": { "sequence": "MLFLAQRRKQTVGGQLLLGQSCFEMLVKLQPRAFFSFLFRHLKELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 351, "header": "tr|A0A8V0YBE2-1|A0A8V0YHT7_CHICK Computationally mapped isoform of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63222567, "end_pos": 63172467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031094.1", "url": "https://www.ensembl.org/id/ENSGALT00010031094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018088.1", "url": "https://www.ensembl.org/id/ENSGALP00010018088.1" } ] } }, { "isoform_ac": "A0A8V0YGT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT6/entry", "sequence": { "sequence": "ALLKQAELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 314, "header": "tr|A0A8V0YGT6-1|A0A8V0YGT6_CHICK Computationally mapped isoform of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63222567, "end_pos": 63175557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031093.1", "url": "https://www.ensembl.org/id/ENSGALT00010031093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018087.1", "url": "https://www.ensembl.org/id/ENSGALP00010018087.1" } ] } }, { "isoform_ac": "A0A8V0YGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU8/entry", "sequence": { "sequence": "MAARNAGTELELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQMAAEGQSDRMASDMEVHLKQRCGIECLHVEKMAPTDIHGYMLNVSGDQTVNAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 369, "header": "tr|A0A8V0YGU8-1|A0A8V0YGU8_CHICK Computationally mapped isoform of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63222567, "end_pos": 63168787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031103.1", "url": "https://www.ensembl.org/id/ENSGALT00010031103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018097.1", "url": "https://www.ensembl.org/id/ENSGALP00010018097.1" } ] } }, { "isoform_ac": "A0A8V0YHT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7/entry", "sequence": { "sequence": "MAARNAGTELETELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 320, "header": "tr|A0A8V0YHT7-1|A0A8V0YHT7_CHICK Isoform 1 of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63222567, "end_pos": 63168787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031106.1", "url": "https://www.ensembl.org/id/ENSGALT00010031106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018100.1", "url": "https://www.ensembl.org/id/ENSGALP00010018100.1" } ] } }, { "isoform_ac": "A0A8V0YJT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT9/entry", "sequence": { "sequence": "MAARNAGTELGKGRRLAGRELCGAQTGPCALYDGWRAAGARRGRLHARFGGPAAASRCRVTSPPACPLLTERNLFKLGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQIFHHVTGSYALPHDLAMA", "length": 383, "header": "tr|A0A8V0YJT9-1|A0A8V0YJT9_CHICK Computationally mapped isoform of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63222567, "end_pos": 63168787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031107.1", "url": "https://www.ensembl.org/id/ENSGALT00010031107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018101.1", "url": "https://www.ensembl.org/id/ENSGALP00010018101.1" } ] } }, { "isoform_ac": "A0A8V0YPL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL3/entry", "sequence": { "sequence": "MAARNAGTELELGWISKVYVNPPAVVRHAEQIQKWRTVKGNWQAAWLLKAVTCIDLTTLSGDDTPSNVHRLCFKAKHPIREDLLKAMDMHDKGITVAAVCVYPARVTDAVNALKAAGCDIPVASVAAGFPSGQTPLETKLAEIKLAVQYGAREIDIVISRSLVLSGQWEGLYEEIRQCREACGEAHMKTILATGELGSLANVYKASMIAMMAGSDFIKTSTGKEVENATLPVGVVMMRAIKEFYWQTGFKVGFKPAGGIRTAKEAITWLMLVKEELGVEWLKPELFRLGASSLLEDIEKQTSGILVSQASDNCYVQAHSVVSKGAPFVHM", "length": 330, "header": "tr|A0A8V0YPL3-1|A0A8V0YPL3_CHICK Computationally mapped isoform of Deoxyribose-phosphate aldolase OS=Gallus gallus OX=9031 GN=DERA PE=1 SV=1 CANONICAL=A0A8V0YHT7-1" }, "locus": { "chromosome": "1", "start_pos": 63221090, "end_pos": 63168787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031095.1", "url": "https://www.ensembl.org/id/ENSGALT00010031095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018089.1", "url": "https://www.ensembl.org/id/ENSGALP00010018089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "deoxyribose-phosphate aldolase activity", "id": "GO:0004139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "deoxyribonucleotide catabolic process", "id": "GO:0009264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" }, { "name": "carbohydrate catabolic process", "id": "GO:0016052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" }, { "name": "deoxyribonucleoside catabolic process", "id": "GO:0046121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12821", "name": "", "equation": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHT7-1" ], "evidence": [ { "id": "12821", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12821" } ] }, { "id": "R-GGA-6787321", "name": "DERA cleaves dR5P to GA3P and CH3CHO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6787328" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6787321", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787321" } ] }, { "id": "R-GGA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V0XQ57-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "O57535-1", "Q90835-1", "A0A8V0ZIP8-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "A0A8V0YHC8-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q02977-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y5M6-1", "A0A8V0YBU4-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798748" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6787328", "participant_name": "dR5P [cytosol]", "crossref": [ { "id": "62877", "database": "ChEBI", "url": "" }, { "id": "ZINC000004228296", "database": "ZINC", "url": "" }, { "id": "ZINC000003869833", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XQ57", "gene_name": "APRT", "activity": [ { "ec_number": "2.4.2.7", "activity": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine.", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] }, { "ec_number": "2.4.2.7", "activity": "", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V1A3K8", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": 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"gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] } ] }, { "uniprot_ac": "A0A8V1AMW1", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] } ] }, { "uniprot_ac": "F1NG97", "gene_name": "AMPD3", "activity": [ { "ec_number": "3.5.4.6", "activity": "AMP + H2O + H(+) = IMP + NH4(+).", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] }, { "ec_number": "3.5.4.6", "activity": "", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] } ] }, { "uniprot_ac": "F1NI04", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] } ] }, { "uniprot_ac": "F1NN63", "gene_name": "PGM1", "activity": [ { "ec_number": "5.4.2.2", "activity": "alpha-D-glucose 1-phosphate = 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Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] } ] }, { "uniprot_ac": "Q90835", "gene_name": "EEF1A", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q90835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90835" } ] } ] }, { "uniprot_ac": "R4GH41", "gene_name": "ASAH1", "activity": [ { "ec_number": "3.5.1.23", "activity": "an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid.", "evidence": [ { "id": "R4GH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH41" } ] }, { "ec_number": "3.5.1.23", "activity": "", "evidence": [ { "id": "R4GH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH41" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.2.4", "ec_name": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "4.1.2.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.4" }, { "id": "4.1.2.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.2.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJV1-1", "uniprot_ac": "A0A8V0YJV1", "uniprot_id": "A0A8V0YJV1_CHICK", "mass": { "chemical_mass": 164051.0, "monoisotopic_mass": 164051.0 }, "refseq": {}, "gene_names": [ { "name": "KIF24", "type": "recommended", "evidence": [ { "id": "A0A8V0YJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ] } ], "protein_names": [ { "name": "Kinesin-like protein KIF24", "type": "recommended", "evidence": [ { "id": "A0A8V0YJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle. Plays an important role in recruiting MPHOSPH9, a negative regulator of cilia formation to the distal end of mother centriole.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1#function" }, { "database": "UniProtKB", "id": "ARBA00057466", "url": "https://www.uniprot.org/uniprotkb/ARBA00057466#function" }, { "database": "UniProtKB", "id": "A0A8V0YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL2#function" }, { "database": "UniProtKB", "id": "A0A8V0YCX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX5#function" }, { "database": "UniProtKB", "id": "A0A8V0YF51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF51#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIF24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1", "locus": { "chromosome": "Z", "start_pos": 8116918, "end_pos": 8150140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011904", "url": "https://www.ensembl.org/id/ENSGALG00010011904" } ] } } ], "crossref": [ { "id": "cd01367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09541", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09541", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBL2", "url": "https://www.orthodb.org/?gene=A0A8V0YBL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCX5", "url": "https://www.orthodb.org/?gene=A0A8V0YCX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCY0", "url": "https://www.orthodb.org/?gene=A0A8V0YCY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF51", "url": "https://www.orthodb.org/?gene=A0A8V0YF51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJV1", "url": "https://www.orthodb.org/?gene=A0A8V0YJV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47971:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47971:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASCLFECLCEADLEKYYPHFAAFGLQKIDELAKISMKDYTKLGVHDMNDRKRLFQLIRIIKIMQEEEAVRDVSKQDFQPSGLFIQPQVTRPGPRRQLRFESFFEENNGTVKESESESYGSSDFNANEEKNSLMDMLEHIQPHDSDLTRLTVRDVNTAGIYTKTELNCTAVSDDIAPLLGDSETPIIQRVTHISGYNYGLPHSYVRSSTSEKETPWTESEKIRVCVRKRPLGQREERRGEVNIITVKDKETLLLHEKKEAVDLTQYILQHVFYFDEVFGESCTNQDVYMKTAHPLIQHVFNGGNATCFAYGQTGAGKTYTMIGTQRNPGLYALAAKDIFRHLEASPSRKDLLVLISFYEIYCGQLYDLLNGRKRLFAREDSKHVVQIVGLREVQVDSVDLLLEVILKGGKERSTGATGVNSDSSRSHAIIQIQIKDTANRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHAHTPFRQSKLTQVLKDSFIGNSKTCMIANVSPSHIATEHTLNTLRYADRVKELKKGVKCSTPVTNRHRTAGNVSPKRIQNSPSLPPGEKSSPKKVKLGLHHPSGATKTKACPPPALQTLSGPLTSTPKGLNKGHSYKGNSGSLWFHHSSPIKGVLRIGHHLKKKTDDLSSCSEKNHTAKDFIIKNAATAETKESLQRDKYMQDRAPAQCLKVQTVQPVQKQYVSRDDFSLGDGNLPSDSRQEWGNTFAKQYVEAWTNLSPFQKEREEHLRLYHQQFQQPPILQQKQSYQPLDRFLTQYKPQEIQVKEELSPTATEAQSKEGMQLEDLDDSDFSEDSFSPVCSQKSVKRRNSNKCSQHSFFLHQREQGTEEEQKGQKRQDLFFKYAIPTQEHEIDDSWDSSEGRPKMEESIKNVGCNKTPSDWSYDLAIGSSLSNTAEKPYCLQDDPACNWNNSKDFLADHKQYKSKHGCLTYSTEDTSTPEKSLSNPYVSPILKLVPPECKQILLQQEKEESSLDGQDVDTGDIKWKTQKNDVSHCRSSSCSSEFSSELMAPLALSLLDCEEGTDTENVSSKRVKSPHMKQMLGRKVHSSQLRFEEETWQCTRSRALTDSMLELREQAHRGARHCILQHSPQAEDKWLSPPWCGEKPCCCLQGPGSSNQGVLHSFVVGNDLTETSTAESTEAREEREGALFLLGKKCEEYSDGRQCDADVNENTGSSGKSDSSQKPNVKSQKINTELTEKSYFSGASCFLTVGNTDYAVQSPPQECGLLQPVSGLRNEDFSSKDSAKSSFSSEEIGLLKSKLMQTIFTQEAFAVDSGSATKVTKLLTNANSPSGSNSGSPTAVPEVGKLHKEALEKAQQAMIRAHQQQLDEMASLCFKEEHLINQMSGMDFQNFIIKLDEILVLKSKSVTELLPCLKCCVPARHQNWAHGLQKKLPKLLQKMVPFLSPSLGLLPGCCFNPCECATSVPPPPAV", "length": 1464, "header": "tr|A0A8V0YJV1-1|A0A8V0YJV1_CHICK Isoform 1 of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL2/entry", "sequence": { "sequence": "MASCLFECLCEADLEKYYPHFAAFGLQKIDELAKISMKDYTKLGVHDMNDRKRLFQLIRIIKIMQEEEAVRDVSKQDFQPSGLFIQPQVTRPGPRRQLRFESFFEENNGTVKESESESYGSSDFNANEEKNSLMDMLEHIQPHDSDLTRLTVRDVNTAGIYTKTELNCTAVSDDIAPLLGDSETPIIQRVTHISGYNYGLPHSYVRSSTSEKETPWTESEKIRVCVRKRPLGQREERRGEVNIITVKDKETLLLHEKKEAVDLTQYILQHVFYFDEVFGESCTNQDVYMKTAHPLIQHVFNGGNATCFAYGQTGAGKTYTMIGTQRNPGLYALAAKDIFRHLEASPSRKDLLVLISFYEIYCGQLYDLLNGRKRLFAREDSKHVVQIVGLREVQVDSVDLLLEVILKGGKERSTGATGVNSDSSRSHAIIQIQIKDTANRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHAHTPFRQSKLTQVLKDSFIGNSKTCMIANVSPSHIATEHTLNTLRYADSMTASKANLISRVKELKKGVKCSTPVTNRHRTAGNVSPKRIQNSPSLPPGEKSSPKKVKLGLHHPSGATKTKACPPPALQTLSGPLTSTPKGLNKGHSYKGNSGSLWFHHSSPIKGVLRIGHHLKKKTDDLSSCSEKNHTAKDFIIKNAATAETKESLQRDKYMQDRAPAQCLKVQTVQPVQKQYVSRDDFSLGDGNLPSDSRQEWGNTFAKQYVEAWTNLSPFQKEREEHLRLYHQQFQQPPILQQKQSYQPLDRFLTQYKPQEIQVKEELSPTATEAQSKEGMQLEDLDDSDFSEDSFSPVCSQKSVKRRNSNKCSQHSFFLHQREQGTEEEQKGQKRQDLFFKYAIPTQEHEIDDSWDSSEGRPKMEESIKNVGCNKTPSDWSYDLAIGSSLSNTAEKPYCLQDDPACNWNNSKDFLADHKQYKSKHGCLTYSTEDTSTPEKSLSNPYVSPILKLVPPECKQILLQQEKEESSLDGQDVDTGDIKWKTQKNDVSHCRSSSCSSEFSSELMAPLALSLLDCEEGTDTENVSSKRVKSPHMKQMLGRKVHSSQLRFEEETWQCTRSRALTDSMLELREQAHRGARHCILQHSPQAEDKWLSPPWCGEKPCCCLQGPGSSNQGVLHSFVVGNDLTETSTAESTEAREEREGALFLLGKKCEEYSDGRQCDADVNENTGSSGKSDSSQKPNVKSQKINTELTEKSYFSGASCFLTVGNTDYAVQSPPQECGLLQPVSGLRNEDFSSKDSAKSSFSSEEIGLLKSKLMQTIFTQEAFAVDSGSATKVTKLLTNANSPSGSNSGSPTAVPEVGKLHKEALEKAQQAMIRAHQQQLDEMASLCFKEEHLINQMSGMDFQNFIIKLDEILVLKSKCIQTMRAQLQLYLSDSPSPDTSLQTSPPV", "length": 1438, "header": "tr|A0A8V0YBL2-1|A0A8V0YJV1_CHICK Computationally mapped isoform of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "locus": { "chromosome": "Z", "start_pos": 8144676, "end_pos": 8119839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028472.1", "url": "https://www.ensembl.org/id/ENSGALT00010028472.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016336.1", "url": "https://www.ensembl.org/id/ENSGALP00010016336.1" } ] } }, { "isoform_ac": "A0A8V0YCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX5/entry", "sequence": { "sequence": "MASCLFECLCEADLEKYYPHFAAFGLQKIDELAKISMKDYTKLGVHDMNDRKRLFQLIRIIKIMQEEEAVRDVSKQDFQPSGLFIQPQVTRPGPRRQLRFESFFEENNGTVKESESESYGSSDFNANEEKNSLMDMLEHIQPHDSDLTRLTVRDVNTAGIYTKTELNCTAVSDDIAPLLGDSETPIIQRVTHISGYNYGLPHSYVRSSTSEKETPWTESEKIRVCVRKRPLGQREERRGEVNIITVKDKETLLLHEKKEAVDLTQYILQHVFYFDEVFGESCTNQDVYMKTAHPLIQHVFNGGNATCFAYGQTGAGKTYTMIGTQRNPGLYALAAKDIFRHLEASPSRKDLLVLISFYEIYCGQLYDLLNGRKRLFAREDSKHVVQIVGLREVQVDSVDLLLEVILKGGKERSTGATGVNSDSSRSHAIIQIQIKDTANRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHAHTPFRQSKLTQVLKDSFIGNSKTCMIANVSPSHIATEHTLNTLRYADRVKELKKGVKCSTPVTNRHRTAGNVSPKRIQNSPSLPPGEKSSPKKVKLGLHHPSGATKTKACPPPALQTLSGPLTSTPKGLNKGHSYKGNSGSLWFHHSSPIKGVLRIGHHLKKKTDDLSSCSEKNHTAKDFIIKNAATAETKESLQRDKYMQDRAPAQCLKVQTVQPVQKQYVSRDDFSLGDGNLPSDSRQEWGNTFAKQYVEAWTNLSPFQKEREEHLRLYHQQFQQPPILQQKQSYQPLDRFLTQYKPQEIQVKEELSPTATEAQSKEGMQLEDLDDSDFSEDSFSPVCSQKSVKRRNSNKCSQHSFFLHQREQGTEEEQKGQKRQDLFFKYAIPTQEHEIDDSWDSSEGRPKMEESIKNVGCNKTPSDWSYDLAIGSSLSNTAEKPYCLQDDPACNWNNSKDFLADHKQYKSKHGCLTYSTEDTSTPEKSLSNPYVSPILKLVPPECKQILLQQEKEESSLDGQDVDTGDIKWKTQKNDVSHCRSSSCSSEFSSELMAPLALSLLDCEEGTDTENVSSKRVKSPHMKQMLGRKVHSSQLRFEEETWQCTRSRALTDSMLELREQAHRGARHCILQHSPQAEDKWLSPPWCGEKPCCCLQGPGSSNQGVLHSFVVGNDLTETSTAESTEAREEREGALFLLGKKCEEYSDGRQCDADVNENTGSSGKSDSSQKPNVKSQKINTELTEKSYFSGASCFLTVGNTDYAVQSPPQECGLLQPVSGLRNEDFSSKDSAKSSFSSEEIGLLKSKLMQTIFTQEAFAVDSGSATKVTKLLTNANSPSGSNSGSPTAVPEVGKLHKEALEKAQQAMIRAHQQQLDEMASLCFKEEHLINQMSGMFRFVAWLQGLFPQGIWNGAIMWFICCDFQLHVMYFQITHESL", "length": 1422, "header": "tr|A0A8V0YCX5-1|A0A8V0YJV1_CHICK Computationally mapped isoform of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "locus": { "chromosome": "Z", "start_pos": 8144676, "end_pos": 8120956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028469.1", "url": "https://www.ensembl.org/id/ENSGALT00010028469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016334.1", "url": "https://www.ensembl.org/id/ENSGALP00010016334.1" } ] } }, { "isoform_ac": "A0A8V0YCY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY0/entry", "sequence": { "sequence": "MASCLFECLCEADLEKYYPHFAAFGLQKIDELAKISMKDYTKLGVHDMNDRKRLFQLIRIIKIMQEEEAVRDVSKQDFQPSGLFIQPQVTRPGPRRQLRFESFFEENNGTVKESESESYGSSDFNANEEKNSLMDMLEHIQPHDSDLTRLTVRDVNTAGIYTKTELNCTAVSDDIAPLLGDSETPIIQRVTHISGYNYGLPHSYVRSSTSEKETPWTESEKIRVCVRKRPLGQREERRGEVNIITVKDKETLLLHEKKEAVDLTQYILQHVFYFDEVFGESCTNQDVYMKTAHPLIQHVFNGGNATCFAYGQTGAGKTYTMIGTQRNPGLYALAAKDIFRHLEASPSRKDLLVLISFYEIYCGQLYDLLNGRKRLFAREDSKHVVQIVGLREVQVDSVDLLLELKECIRALDQEHAHTPFRQSKLTQVLKDSFIGNSKTCMIANVSPSHIATEHTLNTLRYADRVKELKKGVKCSTPVTNRHRTAGNVSPKRIQNSPSLPPGEKSSPKKVKLGLHHPSGATKTKACPPPALQTLSGPLTSTPKGLNKGHSYKGNSGSLWFHHSSPIKGVLRIGHHLKKKTDDLSSCSEKNHTAKDFIIKNAATAETKESLQRDKYMQDRAPAQCLKVQTVQPVQKQYVSRDDFSLGDGNLPSDSRQEWGNTFAKQYVEAWTNLSPFQKEREEHLRLYHQQFQQPPILQQKQSYQPLDRFLTQYKPQEIQVKEELSPTATEAQSKEGMQLEDLDDSDFSEDSFSPVCSQKSVKRRNSNKCSQHSFFLHQREQGTEEEQKGQKRQDLFFKYAIPTQEHEIDDSWDSSEGRPKMEESIKNVGCNKTPSDWSYDLAIGSSLSNTAEKPYCLQDDPACNWNNSKDFLADHKQYKSKHGCLTYSTEDTSTPEKSLSNPYVSPILKLVPPECKQILLQQEKEESSLDGQDVDTGDIKWKTQKNDVSHCRSSSCSSEFSSELMAPLALSLLDCEEGTDTENVSSKRVKSPHMKQMLGRKVHSSQLRFEEETWQCTRSRALTDSMLELREQAHRGARHCILQHSPQAEDKWLSPPWCGEKPCCCLQGPGSSNQGVLHSFVVGNDLTETSTAESTEAREEREGALFLLGKKCEEYSDGRQCDADVNENTGSSGKSDSSQKPNVKSQKINTELTEKSYFSGASCFLTVGNTDYAVQSPPQECGLLQPVSGLRNEDFSSKDSAKSSFSSEEIGLLKSKLMQTIFTQEAFAVDSGSATKVTKLLTNANSPSGSNSGSPTAVPEVGKLHKEALEKAQQAMIRAHQQQLDEMASLCFKEEHLINQMSGMDFQNFIIKLDEILVLKSKCIQTMRAQLQLYLSDSPSPDTSLQTSPPV", "length": 1351, "header": "tr|A0A8V0YCY0-1|A0A8V0YJV1_CHICK Computationally mapped isoform of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "locus": { "chromosome": "Z", "start_pos": 8144676, "end_pos": 8119839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028476.1", "url": "https://www.ensembl.org/id/ENSGALT00010028476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016339.1", "url": "https://www.ensembl.org/id/ENSGALP00010016339.1" } ] } }, { "isoform_ac": "A0A8V0YF51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF51/entry", "sequence": { "sequence": "MASCLFECLCEADLEKYYPHFAAFGLQKIDELAKISMKDYTKLGVHDMNDRKRLFQLIRIIKIMQEEEAVRDVSKQDFQPSGLFIQPQVTRPGPRRQLRFESFFEENNGTVKESESESYGSSDFNANEEKNSLMDMLEHIQPHDSDLTRLTVRDVNTAGIYTKTELNCTAVSDDIAPLLGDSETPIIQRVTHISGYNYGLPHSYVRGNATCFAYGQTGAGKTYTMIGTQRNPGLYALAAKDIFRHLEASPSRKDLLVLISFYEIYCGQLYDLLNGRKRLFAREDSKHVVQIVGLREVQVDSVDLLLEVILKGGKERSTGATGVNSDSSRSHAIIQIQIKDTANRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHAHTPFRQSKLTQVLKDSFIGNSKTCMIANVSPSHIATEHTLNTLRYADRVKELKKGVKCSTPVTNRHRTAGNVSPKRIQNSPSLPPGEKSSPKKVKLGLHHPSGATKTKACPPPALQTLSGPLTSTPKGLNKGHSYKGNSGSLWFHHSSPIKGVLRIGHHLKKKTDDLSSCSEKNHTAKDFIIKNAATAETKESLQRDKYMQDRAPAQCLKVQTVQPVQKQYVSRDDFSLGDGNLPSDSRQEWGNTFAKQYVEAWTNLSPFQKEREEHLRLYHQQFQQPPILQQKQSYQPLDRFLTQYKPQEIQVKEELSPTATEAQSKEGMQLEDLDDSDFSEDSFSPVCSQKSVKRRNSNKCSQHSFFLHQREQGTEEEQKGQKRQDLFFKYAIPTQEHEIDDSWDSSEGRPKMEESIKNVGCNKTPSDWSYDLAIGSSLSNTAEKPYCLQDDPACNWNNSKDFLADHKQYKSKHGCLTYSTEDTSTPEKSLSNPYVSPILKLVPPECKQILLQQEKEESSLDGQDVDTGDIKWKTQKNDVSHCRSSSCSSEFSSELMAPLALSLLDCEEGTDTENVSSKRVKSPHMKQMLGRKVHSSQLRFEEETWQCTRSRALTDSMLELREQAHRGARHCILQHSPQAEDKWLSPPWCGEKPCCCLQGPGSSNQGVLHSFVVGNDLTETSTAESTEAREEREGALFLLGKKCEEYSDGRQCDADVNENTGSSGKSDSSQKPNVKSQKINTELTEKSYFSGASCFLTVGNTDYAVQSPPQECGLLQPVSGLRNEDFSSKDSAKSSFSSEEIGLLKSKLMQTIFTQEAFAVDSGSATKVTKLLTNANSPSGSNSGSPTAVPEVGKLHKEALEKAQQAMIRAHQQQLDEMASLCFKEEHLINQMSGMDFQNFIIKLDEILVLKSKCIQTMRAQLQLYLSDSPSPDTSLQTSPPV", "length": 1331, "header": "tr|A0A8V0YF51-1|A0A8V0YF51_CHICK Computationally mapped isoform of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "locus": { "chromosome": "Z", "start_pos": 8144676, "end_pos": 8119839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028477.1", "url": "https://www.ensembl.org/id/ENSGALT00010028477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016340.1", "url": "https://www.ensembl.org/id/ENSGALP00010016340.1" } ] } }, { "isoform_ac": "A0A8V0YJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1/entry", "sequence": { "sequence": 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"length": 1464, "header": "tr|A0A8V0YJV1-1|A0A8V0YJV1_CHICK Isoform 1 of Kinesin-like protein KIF24 OS=Gallus gallus OX=9031 GN=KIF24 PE=3 SV=1 CANONICAL=A0A8V0YJV1-1" }, "locus": { "chromosome": "Z", "start_pos": 8144676, "end_pos": 8117164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028466.1", "url": "https://www.ensembl.org/id/ENSGALT00010028466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016333.1", "url": "https://www.ensembl.org/id/ENSGALP00010016333.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": 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"microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV1" } ], "pmid": "" }, { 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"MRKPGPQKAIDWKDGKKHKYGRPPESPSQYQGHFTWEKYLKETCAVPAPPHCFKQSYTPPANEFKINMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSQNFFKTGMKLEAVDRKNPHFICPATIGEVRGSEVLITFDGWRGAFDYWCRYDSRDIFPVGWCSLTGDNLQPPGTKVVIPKSPLPASEVNSEKPSMHSSTKTVLGHQQGQGRRKAGKKRGRTTKALIHHPMPAPSKSVEPLKFPRKRGPKPGSKRKPRTLLSPAPTSPTTSTPEPDTSTVPQDAATVPSSAMQAPTVCIYLNKNGSAGPHLDKKKIQRLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFSQHSHAPRSHEYDHDRYLPGETFVLGDGPPGPLEPRMDPMDSALNAVNASGHSRSSREFRLQGYRHLHQPCSLSQGSTSALGRLGSTGSERYREGTRLSSRDPSCWTVEEVMQFIREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLTYHIDKLKQGKQARR", "length": 650, "header": "tr|A0A8V0YI36-1|A0A8V0YI31_CHICK Computationally mapped isoform of Polycomb protein SCMH1 OS=Gallus gallus OX=9031 GN=SCMH1 PE=3 SV=1 CANONICAL=A0A8V0YI31-1" }, "locus": { "chromosome": "23", "start_pos": 1637486, "end_pos": 1613063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"tr|A0A8V0YHE2-1|A0A8V0YHE2_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A8V0YHE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC01/entry", "sequence": { "sequence": "MKSGGGAGGSCPGSMAGRGPGCSLQLPAGTQPPGGGHLYPGESEGPEEESEVFELRPRGREKVRRSTSRDRLDGIILLTKDIQEGDTLNAIALQYCCSVADIKRVNNLINDQDFFALRSIKIPVKKFSVLTETHVSPKGRTVLRPAHYSPEVQEASPDKFTANETAGNFLKEVDRDIEEIVKCNDTKRENLNEVVSALAAQQVCFETDGRSKKCKDPYYGADWGIGWWTAVVIMLIIGIVTPVFYLLYYEVLVKADVSHHSTMESAHSFVTAASHQKQIEHGRSPANSINVDSQGDIRPYNRKPQANVIHRHIT", "length": 314, "header": "tr|A0A8V0YC01-1|A0A8V0YHE2_CHICK Computationally mapped isoform of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=LYSMD3 PE=4 SV=1 CANONICAL=A0A8V0YHE2-1" }, "locus": { "chromosome": "Z", "start_pos": 60506503, "end_pos": 60503651, "strand": "-", "evidence": [ { "database": "Ensembl 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"end_pos": 60503651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031362.1", "url": "https://www.ensembl.org/id/ENSGALT00010031362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018294.1", "url": "https://www.ensembl.org/id/ENSGALP00010018294.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidoglycan binding", "id": "GO:0042834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042834", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE2" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 183, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKD1-1", "uniprot_ac": "A0A8V0YKD1", "uniprot_id": "A0A8V0YKD1_CHICK", "mass": { "chemical_mass": 35013.0, "monoisotopic_mass": 35013.0 }, "refseq": { "ac": "XP_004947761", "name": "GPN-loop GTPase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947761" }, "gene_names": [ { "name": "GPN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YKD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1" } ] }, { "name": "GPN2", "type": "synonym", "evidence": [ { "id": "XP_004947761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947761" } ] } ], "protein_names": [ { "name": "GPN-loop GTPase 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YKD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1/entry#names_and_taxonomy" } ] }, { "name": "GPN-loop GTPase 2", "type": "synonym", "evidence": [ { "id": "XP_004947761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947761" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947761.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947761" } ] }, { "annotation": "Small GTPase involved in the correct assembly of RNA polymerase RNA polymerase II and III (RNAPII and RNAPIII) complexes, ensuring their proper nuclear import.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1#function" }, { "database": "UniProtKB", "id": "RU365059", "url": "https://www.uniprot.org/uniprotkb/RU365059#function" }, { "database": "UniProtKB", "id": "ARBA00094199", "url": "https://www.uniprot.org/uniprotkb/ARBA00094199#function" }, { "database": "UniProtKB", "id": "A0A8V0YQ72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ72#function" }, { "database": "UniProtKB", "id": "A0A8V0YC06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC06#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"categories": [ "Genome Annotation" ] }, { "id": "IPR004130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419576", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATHNYFL", "url": "https://omabrowser.org/oma/group/ATHNYFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC06", "url": "https://www.orthodb.org/?gene=A0A8V0YC06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKD1", "url": "https://www.orthodb.org/?gene=A0A8V0YKD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ72", "url": "https://www.orthodb.org/?gene=A0A8V0YQ72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21231:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21231:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSESSEGSSPLAFGQVVIGPPGSGKTTYCHGMQEFLGRVGRAVAVVNLDPANEGMPYSCAVDISELITLTDVMENLKLGPNGGLIYCMEYLEANFDWLQEKLAAFRGHYYLFDCPGQVELYTHHDALKNVFAQLAKWNFRLAAVHLVDSHYCTDPGKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYGKLAFNLDYYTEVLDLSYLVDHLASDPFFRNYRRLNAKLVEVIEDYSLVSFVPLNVQDKDSMRQVMQAVDKANGCSFGDQEHRSLEALMSAAVGADFHFASTLAVQEKYVQSQDKTVEEEVMDM", "length": 313, "header": "tr|A0A8V0YKD1-1|A0A8V0YKD1_CHICK Isoform 1 of GPN-loop GTPase 2 OS=Gallus gallus OX=9031 GN=GPN2 PE=3 SV=1 CANONICAL=A0A8V0YKD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC06/entry", "sequence": { "sequence": "MSESSEGSSPLAFGQVVIGPPGSGKTTYCHGMQEFLGRVGRAVAVVNLDPANEGMPYSCAVDISELITLTDVMENLKLGPNGGLIYCMEYLEANFDWLQEKLAAFRGHYYLFDCPGQVELYTHHDALKNVFAQLAKWNFRLAAVHLVDSHYCTDPGKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYGKLAFNLDYYTEVLDLSYLVDHLASDPFFRNYRRLNAKLVEVIEDYSLVSFVPLNVQDKDSMRQVMQAVDKANGCSFGDQEHRSLEALMSAAVGADFHFASAGEVCAISGQDGGGRSDGYVTHPTPPQPHSALTALLLLLLKGLSVV", "length": 336, "header": "tr|A0A8V0YC06-1|A0A8V0YKD1_CHICK Computationally mapped isoform of GPN-loop GTPase 2 OS=Gallus gallus OX=9031 GN=GPN2 PE=3 SV=1 CANONICAL=A0A8V0YKD1-1" }, "locus": { "chromosome": "23", "start_pos": 2176135, "end_pos": 2172149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031376.1", "url": "https://www.ensembl.org/id/ENSGALT00010031376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018305.1", "url": "https://www.ensembl.org/id/ENSGALP00010018305.1" } ] } }, { "isoform_ac": "A0A8V0YKD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1/entry", "sequence": { "sequence": "MSESSEGSSPLAFGQVVIGPPGSGKTTYCHGMQEFLGRVGRAVAVVNLDPANEGMPYSCAVDISELITLTDVMENLKLGPNGGLIYCMEYLEANFDWLQEKLAAFRGHYYLFDCPGQVELYTHHDALKNVFAQLAKWNFRLAAVHLVDSHYCTDPGKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYGKLAFNLDYYTEVLDLSYLVDHLASDPFFRNYRRLNAKLVEVIEDYSLVSFVPLNVQDKDSMRQVMQAVDKANGCSFGDQEHRSLEALMSAAVGADFHFASTLAVQEKYVQSQDKTVEEEVMDM", "length": 313, "header": "tr|A0A8V0YKD1-1|A0A8V0YKD1_CHICK Isoform 1 of GPN-loop GTPase 2 OS=Gallus gallus OX=9031 GN=GPN2 PE=3 SV=1 CANONICAL=A0A8V0YKD1-1" }, "locus": { "chromosome": "23", "start_pos": 2176135, "end_pos": 2172229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031366.1", "url": "https://www.ensembl.org/id/ENSGALT00010031366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018298.1", "url": "https://www.ensembl.org/id/ENSGALP00010018298.1" } ] } }, { "isoform_ac": "A0A8V0YQ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ72/entry", "sequence": { "sequence": "MSESSEGSSPLAFGQVVIGPPGSGKTTYCHGMQEFLGRVGRAVAVVNLDPANEGMPYSCAVDISELITLTDVMENLKLGPNGGLIYCMEYLEANFDWLQEKLAAFRGHYYLFDCPGQVELYTHHDALKNVFAQLAKWNFRLAAVHLVDSHYCTDPGKFISVLCTSLSTMLHVELPHVNVLSKMDLIEQYGKLAFNLDYYTEVLDLSYLVDHLASDPFFRNYRRLNAKLVEVIEDYSLVSFVPLNVQVMWWEERGREGRECWRSSQDVWEQLGCTWGKYTFCKGHPCCLCCFSICTQNWL", "length": 299, "header": "tr|A0A8V0YQ72-1|A0A8V0YQ72_CHICK Computationally mapped isoform of GPN-loop GTPase 2 OS=Gallus gallus OX=9031 GN=GPN2 PE=3 SV=1 CANONICAL=A0A8V0YKD1-1" }, "locus": { "chromosome": "23", "start_pos": 2176135, "end_pos": 2173507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031370.1", "url": "https://www.ensembl.org/id/ENSGALT00010031370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018301.1", "url": "https://www.ensembl.org/id/ENSGALP00010018301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419576", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H7F2-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "GPN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALQLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSIFSQMTQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQQVLQAVDKANGYCFGVQEQRSLEAMMSAAMGADFHFSSTLGLQEKYLAPSEQSVEQEAMQL", "length": 310 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A7C0-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "Gpn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLEPLRGHYFLFDCPGQVELCTHHTSLRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFSHYRQLNEKLVQLIEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQRSLEALMSAAVGADFHFSSTLGIQEKYLASSDQTAEQEAMQL", "length": 310 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08726-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "GPN2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPFAQIVIGPPGSGKSTYCNGCSQFFNAIGRHSQVVNMDPANDALPYPCAVDIRDFITLEEIMQEQQLGPNGGLMYAVESLDNSIDLFILQIKSLVEEEKAYLVFDCPGQVELFTHHSSLFNIFKKMEKELDIRFCVVNLIDCFYMTSPSQYISILLLALRSMLMMDLPHINVFSKIDMLKSYGELPFRLDYYTEVQDLDYLEPYIEKEGSSVLGKKYSKLTETIKELVSDFNLVSFEVLSVDDKESMINLQGVIDKANGYIFGASEVGGDTVWAEASREGALIANYDIQDRWIDNKEKYDKEEEEKRTALLKEQELQNKAVDVNEEDEWENALKEWEEKQGMDFVR", "length": 347 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54TE7-1", "protein_name": "GPN-loop GTPase 2 homolog", "gene_name": "gpn2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGFGQVVIGPPGSGKTVYCNGMSQFLQSIGRKVSIINLDPSNENIPYEPAVNIQELIDFQTVVNETDLGPNGGLIFCMEYLEKNLDWLKEKLLPLKDHYIIFDCPGQVELYTHYKIISNILDNIMKWSFRLTVIQVFDSFYCKNPSNFISILLVSLSGMVRIELPHINVLSKMDLIEQNGPLDFNLDFYTDVLDLKYLDAFLDKDPRLKKYSKLNKAIAGVIEDFSLVSFIPLNIMDKKSVANLIASIDKSNGYIYGSLDTNTAILEIQERETQWNFDKYQETQEKYYKSYEDDDVIFENDQDEDYDEFSKYLNR", "length": 315 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q56XY2-1", "protein_name": "GPN-loop GTPase QQT1", "gene_name": "QQT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVFGQVVIGPPGSGKTTYCNGMSQFLSLMGRKVAIVNLDPANDALPYECGVNIEELIKLEDVMSEHSLGPNGGLVYCMEYLEKNIDWLESKLKPLLKDHYILFDFPGQVELFFIHDSTKNVLTKLIKSLNLRLTAVQLIDSHLCCDPGNYVSSLLLSLSTMLHMELPHVNVLSKIDLIGSYGKLAFNLDFYTDVQDLSYLEHHLSQDPRSAKYRKLTKELCSVIEDYSLVNFTTLDIQDKESVGDLVKLIDKSNGYIFAGIDASVVEYSKIAIGQTDWDYNRVAAVQEKYMEDEEIQD", "length": 298 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VEJ1-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "Gpn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANDGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLEPLRGHYFLFDCPGQVELCTHHTALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLEHLASDPFFRRYRQLNEKLVQLVEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSEQTAEQEAMQL", "length": 310 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9Y4-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "GPN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFRAQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSNQSVEQEAMQL", "length": 310 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VU67-1", "protein_name": "GPN-loop GTPase 2", "gene_name": "Dmel\\CG10222", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMQRFPTQATVENPRYGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERERYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTDVLDLKYLLDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGYVYKAGEEQTVNSLLACAVGAETEAARMEHDVQPYME", "length": 307 }, "evidence": [ { "id": "A0A8V0YKD1", "url": "https://omabrowser.org/oma/group/A0A8V0YKD1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKI3-1", "uniprot_ac": "A0A8V0YKI3", "uniprot_id": "A0A8V0YKI3_CHICK", "mass": { "chemical_mass": 70281.0, "monoisotopic_mass": 70281.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ribonuclease H", "type": "recommended", "evidence": [ { "id": "A0A8V0YKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3/entry#names_and_taxonomy" } ] }, { "name": "3.1.26.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3", "locus": {} } ], "crossref": [ { "id": "cd03715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YC50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGEPKFPKTRVSRGDRRPYVELMIHWSRKNVQRVMALVDTGAETSIIYGDPNQFSGSKAMIGGFGGQMIPVTQTWLKLGVGRLPPREYKVYIAPIPEYILGIDILSGLTLQTTVGEFRLRERCISIRAVQAIIRGHAEIEPICLSQPRRITNTKQYRLPGGQQEITKTVQELERVGIIRPAHSPYNSPIWPVRKPDGTWRMTVDYRELNKVTPLIHAAVPNIASLMDTLSREIETYHCVLDLANAFFSIPIAKESQDQFAFTWEGRQWTFQVLPQGYVHSPTFCHNLVARDLANWNKPSTVKMFHYIDYLMLTSDSIEVLEKTVPSLITYLQEKGWAINPQKVQGPGLSVKFLGVVWSGKTKVLPSAIIDKIQAFPVPTKPKQLQEFWGILGYWRSFIPHLAQLLKPLYRLTKKGQVWDWGRTEQEAFQQAKIAVKQAQALGIFDPTLPAELDVHVTQEGFGWGLWQRQSSVRIPIGFWSQIWHGAEERYSMVEKLLLATYSALQAVEPITQTTEVIVKTTLPIQGWVKDLTHIPKTWVAQPQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSTGGEIPYPRRCLVYRWIQQREPK", "length": 616, "header": "tr|A0A8V0YKI3-1|A0A8V0YKI3_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YKI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC50/entry", "sequence": { "sequence": "MTVDYRELNKVTPLIHAAVPNIASLMDTLSREIETYHCVLDLANAFFSIPIAKESQDQFAFTWEGRQWTFQVLPQGYVHSPTFCHNLVARDLANWNKPSTVKMFHYIDYLMLTSDSIEVLEKTVPSLITYLQEKGWAINPQKVQGPGLSVKFLGVVWSGKTKVLPSAIIDKIQAFPVPTKPKQLQEFWGILGYWRSFIPHLAQLLKPLYRLTKKGQVWDWGRTEQEAFQQAKIAVKQAQALGIFDPTLPAELDVHVTQEGFGWGLWQRQSSVRIPIGFWSQIWHGAEERYSMVEKLLLATYSALQAVEPITQTTEVIVKTTLPIQGWVKDLTHIPKTWVAQPQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSTGGEIPYPRRCLVYRWIQQREPK", "length": 415, "header": "tr|A0A8V0YC50-1|A0A8V0YKI3_CHICK Computationally mapped isoform of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YKI3-1" }, "locus": { "chromosome": "4", "start_pos": 18015442, "end_pos": 18015340, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031444.1", "url": "https://www.ensembl.org/id/ENSGALT00010031444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018357.1", "url": "https://www.ensembl.org/id/ENSGALP00010018357.1" } ] } }, { "isoform_ac": "A0A8V0YKI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3/entry", "sequence": { "sequence": "MTGEPKFPKTRVSRGDRRPYVELMIHWSRKNVQRVMALVDTGAETSIIYGDPNQFSGSKAMIGGFGGQMIPVTQTWLKLGVGRLPPREYKVYIAPIPEYILGIDILSGLTLQTTVGEFRLRERCISIRAVQAIIRGHAEIEPICLSQPRRITNTKQYRLPGGQQEITKTVQELERVGIIRPAHSPYNSPIWPVRKPDGTWRMTVDYRELNKVTPLIHAAVPNIASLMDTLSREIETYHCVLDLANAFFSIPIAKESQDQFAFTWEGRQWTFQVLPQGYVHSPTFCHNLVARDLANWNKPSTVKMFHYIDYLMLTSDSIEVLEKTVPSLITYLQEKGWAINPQKVQGPGLSVKFLGVVWSGKTKVLPSAIIDKIQAFPVPTKPKQLQEFWGILGYWRSFIPHLAQLLKPLYRLTKKGQVWDWGRTEQEAFQQAKIAVKQAQALGIFDPTLPAELDVHVTQEGFGWGLWQRQSSVRIPIGFWSQIWHGAEERYSMVEKLLLATYSALQAVEPITQTTEVIVKTTLPIQGWVKDLTHIPKTWVAQPQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSTGGEIPYPRRCLVYRWIQQREPK", "length": 616, "header": "tr|A0A8V0YKI3-1|A0A8V0YKI3_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YKI3-1" }, "locus": { "chromosome": "4", "start_pos": 18015442, "end_pos": 18013336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031440.1", "url": "https://www.ensembl.org/id/ENSGALT00010031440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018355.1", "url": "https://www.ensembl.org/id/ENSGALP00010018355.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" }, { "id": "PS50175", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A2", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 105, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI3" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 358, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHU1-1", "uniprot_ac": "A0A8V0YHU1", "uniprot_id": "A0A8V0YHU1_CHICK", "mass": { "chemical_mass": 175910.0, "monoisotopic_mass": 175910.0 }, "refseq": { "ac": "XP_015147044", "name": "ATP-binding cassette sub-family C member 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147044" }, "gene_names": [ { "name": "ABCC9", "type": "recommended", "evidence": [ { "id": "A0A8V0YHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ] }, { "name": "ABCC9", "type": "synonym", "evidence": [ { "id": "XP_015147044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147044" } ] } ], "protein_names": [ { "name": "ATP binding cassette subfamily C member 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family C member 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147044" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147044.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABCC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1", "locus": { "chromosome": "1", "start_pos": 66997879, "end_pos": 66924027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013156", "url": "https://www.ensembl.org/id/ENSGALG00010013156" } ] } } ], "crossref": [ { "id": "cd03288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418200", "url": "https://www.ncbi.nlm.nih.gov/gene/418200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418200", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418200", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLYALTX", "url": "https://omabrowser.org/oma/group/LLYALTX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCA9", "url": "https://www.orthodb.org/?gene=A0A8V0YCA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHU1", "url": "https://www.orthodb.org/?gene=A0A8V0YHU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHU7", "url": "https://www.orthodb.org/?gene=A0A8V0YHU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP2", "url": "https://www.orthodb.org/?gene=A0A8V0YKP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5578775", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSLEASRSKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPENLLSQEDGIFASFVRADM", "length": 1558, "header": "tr|A0A8V0YHU1-1|A0A8V0YHU1_CHICK Isoform 1 of ATP binding cassette subfamily C member 9 OS=Gallus gallus OX=9031 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A8V0YHU1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA9/entry", "sequence": { "sequence": "MRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSLEASRSKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSHILDANIVLVLSDGFLVECDTASNLLLKEDGLFTTLVKTHK", "length": 1558, "header": "tr|A0A8V0YCA9-1|A0A8V0YHU1_CHICK Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Gallus gallus OX=9031 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A8V0YHU1-1" }, "locus": { "chromosome": "1", "start_pos": 66996399, "end_pos": 66931170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031551.1", "url": "https://www.ensembl.org/id/ENSGALT00010031551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018430.1", "url": "https://www.ensembl.org/id/ENSGALP00010018430.1" } ] } }, { "isoform_ac": "A0A8V0YHU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1/entry", "sequence": { "sequence": "MRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSLEASRSKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPENLLSQEDGIFASFVRADM", "length": 1558, "header": "tr|A0A8V0YHU1-1|A0A8V0YHU1_CHICK Isoform 1 of ATP binding cassette subfamily C member 9 OS=Gallus gallus OX=9031 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A8V0YHU1-1" }, "locus": { "chromosome": "1", "start_pos": 66997711, "end_pos": 66931170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031558.1", "url": "https://www.ensembl.org/id/ENSGALT00010031558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018434.1", "url": "https://www.ensembl.org/id/ENSGALP00010018434.1" } ] } }, { "isoform_ac": "A0A8V0YHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU7/entry", "sequence": { "sequence": "MRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPENLLSQEDGIFASFVRADM", "length": 1545, "header": "tr|A0A8V0YHU7-1|A0A8V0YHU7_CHICK Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Gallus gallus OX=9031 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A8V0YHU1-1" }, "locus": { "chromosome": "1", "start_pos": 66997711, "end_pos": 66931170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031563.1", "url": "https://www.ensembl.org/id/ENSGALT00010031563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018439.1", "url": "https://www.ensembl.org/id/ENSGALP00010018439.1" } ] } }, { "isoform_ac": "A0A8V0YKP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP2/entry", "sequence": { "sequence": "MFWMHESAADVGVRCFSDCILQSVQNRVIIQQADLLEAMRLAFCGNDNASAYNITAGVLRNVCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFTLLFVHVCEIAEGIVSDTQMKSRHLHLFLPAIIGFVAATVSIVYYHNIETSNFPKLLLALFLYWIMAFVTKTIKFVRYCQDGVSFSQLRFCITGIMVILYGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPVDLKAIGKLPIAMRALTNYVCLKEAYEEQKKKVADQPNRSPSIWLAMYSAFGRPILLSSTFRYLADLLGFAGPLCISGIVQGFQNTTNGTNTTEKDPSNSYLSSEEFFRNVYVLAVLLFLALILQRTFLQASYYVTTETGINLRGALLAMIYDKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGIILLHHLLGVSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKNVEETRMKELTSLKTFALHTSLSIFMNAAIPIAAVLATFVTYAYSNDEPLQPAQAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGDDSWRGGDNSVAYESCKKHTGLHTKAINRRQPLRYQLENYEQSSRRQTRPVETDDIAIKVTNGYFSWGSGLATLSNINIRIPTGQMTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSLEASRSKNRYSVAYAAQKPWLLNATVEENIIFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNVVFLDDPFSALDIHLSDHLMQEGILKFLQEDKRTLVLVTHKLQYLPHADWIIAMKDGMVLREGTLKDIQNNDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYPRESKAQLEDEDEEEEEEEDEDDNMSTVLRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSTDNRKEFGNADVQNTGKTYHVAVFGILSGAGIVLCLITSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDMTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPWFLVALMPLGIAFYFIQKYFRVASKDLQELDDSTLLPLLCHFSETAEGLTTIRAFRHESRFKQRMLELTDTNNIAYLFLSAANIWLEVRMDYLGACIVLTAAITSITEGPDSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVHSFLNMESENYDGYLDASQVPKDWPQEGEIKIENLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGRIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDTLWEALEIAQLKNMVKSLPGGLDAMVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPENLLSQEDGIFASFVRADM", "length": 1596, "header": "tr|A0A8V0YKP2-1|A0A8V0YKP2_CHICK Computationally mapped isoform of ATP binding cassette subfamily C member 9 OS=Gallus gallus OX=9031 GN=ABCC9 PE=3 SV=1 CANONICAL=A0A8V0YHU1-1" }, "locus": { "chromosome": "1", "start_pos": 66997711, "end_pos": 66924510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031554.1", "url": "https://www.ensembl.org/id/ENSGALT00010031554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018433.1", "url": "https://www.ensembl.org/id/ENSGALP00010018433.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418200", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296025", "resource": "Reactome", "description": "ATP sensitive Potassium channels" }, { "id": "R-GGA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-GGA-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578775", "resource": "Reactome", "description": "Ion homeostasis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VEZ1-1", "protein_name": "ATP binding cassette subfamily C member 9", "gene_name": "ABCC9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLSFCGNNISSYNIYDGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQSGWGVSDLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYTAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNATGISEKLSSKEFLENSYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRSGESSLPFESCKKHTGVPPKTINRKQPGRYHLDSYEQSTRRLHPAETEDIAIKVTNGYFSWGSGLATLSNINIQIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQLEDEDEEEEEEEEEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYNIKNTGKTDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDTTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPVLFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAREDGVFASFVRADM", "length": 1549 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BBT3-1", "protein_name": "ATP-binding cassette sub-family C member 9 isoform X1", "gene_name": "abcc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALSFCGNDRDSNAYSVDNGVLDNGCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNMRWILTFTLLFVHVCEIAEGIVSNTQMESNHLHLFMPAFMGFIAATTSVVYYHNIETANFPKLLLALFIYWILAFITKMIKLWKFAEASLGVQHLRFCITALLVVLYGLLMAVEINVIRVRKYVFFANPQRVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNPLIIGAHKRPIELKKIGKLPIAMRALTNYLRLKDSYEEQRQNTEDPEKSPSIWKSMYRAFGGSILLSSTFRYMADLLGFAGPLCISGIVEHLHNSTEIDRTNKTGNMTFGVYFMSSTELLQNTSVLAVLLFLALVLQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNMSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYYLLGNSALIGAGVILLLAPVQYLIATKLADIQKSTLDYSTDRLKKTTEILKGIKLLKLYAWENIFCDRVEETRGKELTSLKTFALHTSMSIFMNAAIPIAAVLATFVTHAYIEEDRLSPAKAFASLALFHILVTPLFLLSTVVRFAVKALVSVQKLSEFLQSDEIGDDSWRNGDMCMSLEVGKKYKYQGDTKAINRKGRYRMDNYEQPVRRQLRPSETEDVAVQVNDGFFTWGSNLSTLSDINIRIPTGQLTMIVGQVGCGKSSLLLAMLGEMQTISGKVYWSKLPDCEILFDGNISGHDMELSHEERSKNRYSVAYATQKSWLLNATVEENITFGSPFNKQRYKAVIDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLIHADWIIAMKDGSVLREGTLKDIQTHDVELYEHWKTLMNRQDQELEKDTDLESQTTLERKTLRRAFYSREAKNHVDDEDEEEEVEEEDDDNMSTTTSRRSKIPWKMCCCYLSSGGFLMVFLMVSSKLAKHSVMVAIDYWLAAWTSSNPHNQSFVNSSFNHTLNDDATQIAEHRSYVPVFIILCAAAIALCLITSLTVEFLGVAAATNLHHNLLNKIIHAPIRFFDVTPLGQILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGVIAFVTPAFLIALVPLAVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHEARFKQRMLELTDTNNTAYLFLSAANRWLEVRTDYLGAVIVLTAAVAAIWSTSPSGLVGLGLTYALTLTNYLNWVVRNLADLEVQMAAVKKVNSFLSTESENYEGSMDVSQVPEDWPQHGEITIHDLCVRYDSMLKPVLKHVNAHINPGQKVGICGRTGSGKSSLSLAFFNMVDVFEGKIVIDGIDICKLPLQTLRSRLSIILQDPVLFSGSIRLNLDPERTCTDDRLWEALEIAQLKNMVKALPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHLVSSILEAEQVLVFSSGILVENDSAINLLAQEDSLFGILVRTHK", "length": 1583 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60706-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "ABCC9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTGESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK", "length": 1549 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70170-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "Abcc9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSFCGNNISSYNIYYGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSHRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGVSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEKTNTTREMFPETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRAGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQARRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEEDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK", "length": 1546 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63563-1", "protein_name": "ATP-binding cassette sub-family C member 9", "gene_name": "Abcc9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSFCGNNISSYNIYHGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSQRASRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYWQLGWGMSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKAIGKLPIAMRAVTNYVCLKEAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNEPKNNTTRFSETLSSKEFLENAHVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDNYEQARRLRPAETEDVAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSSFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINDPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLIALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK", "length": 1545 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8LGU1-1", "protein_name": "ABC transporter C family member 8", "gene_name": "ABCC8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAFIGSLPWCDVELNLASSCFQRTAIAFVNLLFLCIFYLFLIASCVSTHFIVRGRKKGWIFVAVAICCAITSFIFLGVGLNSLIHGGNDVTEISWVACFVEGIIWVSLAVSLLVNGSKWVNILVSVWWVSFALLDLVAKSGILLQGNGIRILDILTLPMSLLLLLCSWMNLRSSSAAAQDCSVTGLSDPLLTKNPRKESARLATAGFFSILSFSWMNPLLSLGFKKPLSPEDIPSVVPEDEAQLAYKKFSQAWDTLLGDESSTKERNLVFRAVVKVYFKENIFIAVFAFLRTFAVVSLPLMLYVFVDYANSDHRDLRNGFFNLACLVMLKLVESLTMRHWYFASRRSGMRIRSALMVAAYKKQLKLSSLGRKRHSSGEIVNYIAVDAYRMGEFLWWFHSGWSLSLQLLLSTAVLFGVVGAGAFPGLILLLLCGLLNLPFAKMLQNCQTQFMIAQDKRLRSTSEILNSMKVIKLQSWEDEFKKKIESCRDDEFTWLAKAQLTKAFGSFLYWMSPTIVSSVVFLGCALLKSAPLNASTIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFLLDDELKMDEIERSGLDASGTAVDIQVGNFGWEPETKIPTLRNIHLEIKHGQKVAVCGPVGAGKSSLLHAVLGEIPKVSGTVKVFGSIAYVSQTSWIQSGTIRDNILYGKPMESRRYNAAIKACALDKDMNGFGHGDLTEIGQRGINLSGGQKQRIQLARAVYADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKEKTVILVTHQVEFLSEVDQILVMEEGTITQSGKYEELLMMGTAFQQLVNAHNDAVTVLPLASNESLGDLRKEGKDREIRNMTVVEKIEEEIEKTDIPGVQLTQEEEKESGYVGMKPFLDYIGVSRGWCLLWSSVLGQVGFVVFQAASTYWLAFAIGIPKITNTMLIGVYSIISTLSAGFVYARAITTAHLGLKASKAFFSGFTNAVFKAPMLFFDSTPVGRILTRASSDLNVLDYDVPFAFIFVVAPAVELTAALLIMTYVTWQVIIIALLALAATKVVQDYYLASARELIRINGTTKAPVMNYAAETSLGVVTIRAFGTAERFFKNYLNLVDADAVLFFLSNAAMEWVILRIETLQNVTLFTCALLLILIPKGYIAPGLVGLSLSYALTLTQTQVFLTRWYCTLSNSIISVERIKQYMNIPEEPPAIIDDKRPPSSWPSNGTIHLQELKIRYRPNAPLVLKGISCTFREGTRVGVVGRTGSGKSTLISALFRLVEPASGCILIDGIDISKIGLKDLRMKLSIIPQEPTLFRGCIRTNLDPLGVYSDDEIWKALEKCQLKTTISNLPNKLDSSVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASIDSATDAIIQRIIREEFADCTVITVAHRVPTVIDSDMVMVLSFGDLVEYNEPSKLMETDSYFSKLVAEYWASCRGNSSQNLQL", "length": 1464 }, "evidence": [ { "id": "A0A8V0YHU1", "url": "https://omabrowser.org/oma/group/A0A8V0YHU1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "sulfonylurea receptor activity", "id": "GO:0008281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "inward rectifying potassium channel", "id": "GO:0008282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008282", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to ATP", "id": "GO:0033198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": 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"Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU1" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 676, "end_pos": 916, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 1457, "end_pos": 1459 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 328, 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"name": "2.7.10.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VEGFRKDRL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8", "locus": {} } ], "crossref": [ { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCG4", "url": "https://www.orthodb.org/?gene=A0A8V0YCG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX4", "url": "https://www.orthodb.org/?gene=A0A8V0YFX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP8", "url": "https://www.orthodb.org/?gene=A0A8V0YKP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416:SF552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRNAGLAEDEFFEKPVLSIAKDHIVILPGEDLKIKCRGARPVSWLLGEAQRKDPRVDISSCRNNSRQSCSTLLLRNVTASDTGYLTCVHDDAPSREELTAKIYVFVEDYRNPFVEFYPEHPQIIYLLEAKKTVVIPCRVTSPDIRPQLMQYPHREKLKFKKMVWDPKRGFVIPSPAFTYSGVLTCTAGINGSVFTSYYLVQKLEDRVQNLALKATPKKLLVGETLYLECKAETFINGRIEFIWTCPNGKHPYPRRGMDRSKPVYKFGSSLTIENVTMEDGGLYICRTFNLTSLEANVTVTVYDKPFLEVSHKKGLYYEITSGHKSLKLAAKVDAFPRPTVTWYKDGKLIKDNQSCYEPDPAKYRLGIRDVRPKHAGNYTIVLSNAKHGLYKNLTMQLVVTERPKIYEKETDFDKIERVELRSEHKIQCTVSGNPDPKVEWKWQPCSLTDTRCNPKGQKIVVQENMFIGNKIKSIENITMKHGDKRKIVSTLTMENSSTSGIYYCVASNKVGEEERSIEFYVSDVPSGLQTAPQVTAIAGSTAQLTCRASRYIYSNLAWSYPSLGAAHGSSLTRSADAYSISLTLIIANVTEEHSGLYKCRAQHQHNGSDTLEQHTRLLIRAKAAPYILQNLTDLEVNISGKIILECRVSGTPEPQVTWSKDGYPISAASGISMENNTLVIERVKKDDEGLYECKATNDMGQDSTSAFIKIQGSEEKSNIEVIILVCTGLAATLFWLLLTLFIRKLRKPDATDIKTGYLSIIMDPEEMPLDEQCDRLPYDSSKWEFPRDRLRLGKTLGHGAFGKVVEASAFGIDKSSTCKTVAVKMLKECATTNECKALMSELKILIHIGHHLNVVNLLGACTKAGGPLMVIVEYCKYGNLSNYLRGKRGDFIAYKSQENSGQAEKSLDESSSDLTELIKRRLESVASTGSSASSGFIEDKSYSDSEEDEEDAEDLYKRPLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLLWEIFSLGASPYPGVQIDEDFCRRLKEGTRMRSPEYSTPEVYQTMLDCWHGVPTERPTFTELVERLGDLLQANVQQDGKDYIPLNITLCPDGEPNSKTCPVEENLNNCVNRWSAVETGSGSKRRPLSVKTFDEVSVGKEKVMHEESDSGMVLTSDEIKSPKRLEIRSWPYGIMALARRAVNKSKESILSDHEREAVKYQPAVQVEEDTMDFPLEDSVLLPMDPSLECHSPPPDYNSVVQCSAPPV", "length": 1300, "header": "tr|A0A8V0YKP8-1|A0A8V0YKP8_CHICK Isoform 1 of receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=VEGFRKDRL PE=3 SV=1 CANONICAL=A0A8V0YKP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG4/entry", "sequence": { "sequence": 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"length": 1297, "header": "tr|A0A8V0YCG4-1|A0A8V0YKP8_CHICK Computationally mapped isoform of receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=VEGFRKDRL PE=3 SV=1 CANONICAL=A0A8V0YKP8-1" }, "locus": { "chromosome": "4", "start_pos": 12001531, "end_pos": 11883633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028876.1", "url": "https://www.ensembl.org/id/ENSGALT00010028876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016635.1", "url": "https://www.ensembl.org/id/ENSGALP00010016635.1" } ] } }, { "isoform_ac": "A0A8V0YFX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX4/entry", "sequence": { "sequence": "MLGGPSAALAACALQALLLTLGLAEDEFFEKPVLSIAKDHIVILPGEDLKIKCRGARPVSWLLGEAQRKDPRVDISSCRNNSRQSCSTLLLRNVTASDTGYLTCVHDDAPSREELTAKIYVFVEDYRNPFVEFYPEHPQIIYLLEAKKTVVIPCRVTSPDIRPQLMQYPHREKLKFKKMVWDPKRGFVIPSPAFTYSGVLTCTAGINGSVFTSYYLVQKLEDRVQNLALKATPKKLLVGETLYLECKAETFINGRIEFIWTCPNGKHPYPRRGMDRSKPVYKFGSSLTIENVTMEDGGLYICRTFNLTSLEANVTVTVYDKPFLEVSHKKGLYYEITSGHKSLKLAAKVDAFPRPTVTWYKDGKLIKDNQSCYEPDPAKYRLGIRDVRPKHAGNYTIVLSNAKHGLYKNLTMQLVVTERPKIYEKETDFDKIERVELRSEHKIQCTVSGNPDPKVEWKWQPCSLTDTRCNPKGQKIVVQENMFIGNKIKSIENITMKHGDKRKIVSTLTMENSSTSGIYYCVASNKVGEEERSIEFYVSDVPSGLQTAPQVTAIAGSTAQLTCRASRYIYSNLAWSYPSLGAAHGSSLTRSADAYSISLTLIIANVTEEHSGLYKCRAQHQHNGSDTLEQHTRLLIRAKAAPYILQNLTDLEVNISGKIILECRVSGTPEPQVTWSKDGYPISAASGISMENNTLVIERVKKDDEGLYECKATNDMGQDSTSAFIKIQGSEEKSNIEVIILVCTGLAATLFWLLLTLFIRKLRKPDATDIKTGYLSIIMDPEEMPLDEQCDRLPYDSSKWEFPRDRLRLECATTNECKALMSELKILIHIGHHLNVVNLLGACTKAGGPLMVIVEYCKYGNLSNYLRGKRGDFIAYKSQENSGQAEKSLDESSSDLTELIKRRLESVASTGSSASSGFIEDKSYSDSEEDEEDAEDLYKRPLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLLWEIFSLGASPYPGVQIDEDFCRRLKEGTRMRSPEYSTPEVYQTMLDCWHGVPTERPTFTELVERLGDLLQANVQQDGKDYIPLNITLCPDGEPNSKTCPVEENLNNCVNRWSAVETGSGSKRRPLSVKTFDEVSVGKEKVMHEESDSGMVLTSDEIKSPKRLEIRSWPYGIMALARRAVNKSKESILSDHEREAVKYQPAVQVEEDTMDFPLEDSVLLPMDPSLECHSPPPDYNSVVQCSAPPV", "length": 1281, "header": "tr|A0A8V0YFX4-1|A0A8V0YFX4_CHICK Computationally mapped isoform of receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=VEGFRKDRL PE=4 SV=1 CANONICAL=A0A8V0YKP8-1" }, "locus": { "chromosome": "4", "start_pos": 12001531, "end_pos": 11883633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028875.1", "url": "https://www.ensembl.org/id/ENSGALT00010028875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016634.1", "url": "https://www.ensembl.org/id/ENSGALP00010016634.1" } ] } }, { "isoform_ac": "A0A8V0YKP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8/entry", "sequence": { "sequence": "MSRNAGLAEDEFFEKPVLSIAKDHIVILPGEDLKIKCRGARPVSWLLGEAQRKDPRVDISSCRNNSRQSCSTLLLRNVTASDTGYLTCVHDDAPSREELTAKIYVFVEDYRNPFVEFYPEHPQIIYLLEAKKTVVIPCRVTSPDIRPQLMQYPHREKLKFKKMVWDPKRGFVIPSPAFTYSGVLTCTAGINGSVFTSYYLVQKLEDRVQNLALKATPKKLLVGETLYLECKAETFINGRIEFIWTCPNGKHPYPRRGMDRSKPVYKFGSSLTIENVTMEDGGLYICRTFNLTSLEANVTVTVYDKPFLEVSHKKGLYYEITSGHKSLKLAAKVDAFPRPTVTWYKDGKLIKDNQSCYEPDPAKYRLGIRDVRPKHAGNYTIVLSNAKHGLYKNLTMQLVVTERPKIYEKETDFDKIERVELRSEHKIQCTVSGNPDPKVEWKWQPCSLTDTRCNPKGQKIVVQENMFIGNKIKSIENITMKHGDKRKIVSTLTMENSSTSGIYYCVASNKVGEEERSIEFYVSDVPSGLQTAPQVTAIAGSTAQLTCRASRYIYSNLAWSYPSLGAAHGSSLTRSADAYSISLTLIIANVTEEHSGLYKCRAQHQHNGSDTLEQHTRLLIRAKAAPYILQNLTDLEVNISGKIILECRVSGTPEPQVTWSKDGYPISAASGISMENNTLVIERVKKDDEGLYECKATNDMGQDSTSAFIKIQGSEEKSNIEVIILVCTGLAATLFWLLLTLFIRKLRKPDATDIKTGYLSIIMDPEEMPLDEQCDRLPYDSSKWEFPRDRLRLGKTLGHGAFGKVVEASAFGIDKSSTCKTVAVKMLKECATTNECKALMSELKILIHIGHHLNVVNLLGACTKAGGPLMVIVEYCKYGNLSNYLRGKRGDFIAYKSQENSGQAEKSLDESSSDLTELIKRRLESVASTGSSASSGFIEDKSYSDSEEDEEDAEDLYKRPLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLLWEIFSLGASPYPGVQIDEDFCRRLKEGTRMRSPEYSTPEVYQTMLDCWHGVPTERPTFTELVERLGDLLQANVQQDGKDYIPLNITLCPDGEPNSKTCPVEENLNNCVNRWSAVETGSGSKRRPLSVKTFDEVSVGKEKVMHEESDSGMVLTSDEIKSPKRLEIRSWPYGIMALARRAVNKSKESILSDHEREAVKYQPAVQVEEDTMDFPLEDSVLLPMDPSLECHSPPPDYNSVVQCSAPPV", "length": 1300, "header": "tr|A0A8V0YKP8-1|A0A8V0YKP8_CHICK Isoform 1 of receptor protein-tyrosine kinase OS=Gallus gallus OX=9031 GN=VEGFRKDRL PE=3 SV=1 CANONICAL=A0A8V0YKP8-1" }, "locus": { "chromosome": "4", "start_pos": 12001531, "end_pos": 11914108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028873.1", "url": "https://www.ensembl.org/id/ENSGALT00010028873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016632.1", "url": "https://www.ensembl.org/id/ENSGALP00010016632.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "endothelial cell differentiation", "id": "GO:0045446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor activity", "id": "GO:0005021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1236, "end_pos": 1238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", 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"L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWW2", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] } ] }, { "uniprot_ac": "A0A8V0YXM5", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] } ] }, { "uniprot_ac": "A0A8V0YYC1", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YYC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC1" } ] } ] }, { "uniprot_ac": "A0A8V0YYI3", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ7", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": 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"ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": 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{ "start_pos": 496, "end_pos": 498 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 880, "end_pos": 882 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIS9-1", "uniprot_ac": "A0A8V0YIS9", "uniprot_id": "A0A8V0YIS9_CHICK", "mass": { "chemical_mass": 177271.0, "monoisotopic_mass": 177271.0 }, "refseq": { "ac": "XP_003643023", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643023" }, "gene_names": [ { "name": "ADAMTS12", "type": "recommended", "evidence": [ { "id": "A0A8V0YIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS9" } ] }, { "name": "ADAMTS12", "type": "synonym", "evidence": [ { "id": "XP_003643023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643023" } ] } ], "protein_names": [ { "name": "A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643023" } ] }, { "name": "ADAM metallopeptidase with thrombospondin type 1 motif 12", "type": "synonym", "evidence": [ { "id": "A0A8V0YIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643023.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAMTS12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS9", "locus": { "chromosome": "Z", "start_pos": 10663212, "end_pos": 10862979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013174", "url": "https://www.ensembl.org/id/ENSGALG00010013174" } ] } } ], "crossref": [ { "id": "cd04273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04273", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGLHHPV", "url": 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"MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1580, "header": "tr|A0A8V0YIS9-1|A0A8V0YIS9_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH3/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1529, "header": "tr|A0A8V0YCH3-1|A0A8V0YIS9_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10694816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031635.1", "url": "https://www.ensembl.org/id/ENSGALT00010031635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018500.1", "url": "https://www.ensembl.org/id/ENSGALP00010018500.1" } ] } }, { "isoform_ac": "A0A8V0YHX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX8/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTPLAFSNKKIIGGRNGNKIMWLSERFLGDLSARSDGWRRLWLQTVRWLNIMEA", "length": 212, "header": "tr|A0A8V0YHX8-1|A0A8V0YIS9_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10770296, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031596.1", "url": "https://www.ensembl.org/id/ENSGALT00010031596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018464.1", "url": "https://www.ensembl.org/id/ENSGALP00010018464.1" } ] } }, { "isoform_ac": "A0A8V0YIS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS5/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNEQAIQLFTNHTRSTVL", "length": 233, "header": "tr|A0A8V0YIS5-1|A0A8V0YIS9_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10780906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031594.1", "url": "https://www.ensembl.org/id/ENSGALT00010031594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018462.1", "url": "https://www.ensembl.org/id/ENSGALP00010018462.1" } ] } }, { "isoform_ac": "A0A8V0YIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS9/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1580, "header": "tr|A0A8V0YIS9-1|A0A8V0YIS9_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10694816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031599.1", "url": "https://www.ensembl.org/id/ENSGALT00010031599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018467.1", "url": "https://www.ensembl.org/id/ENSGALP00010018467.1" } ] } }, { "isoform_ac": "A0A8V0YIT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT3/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1565, "header": "tr|A0A8V0YIT3-1|A0A8V0YIT3_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10694816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031605.1", "url": "https://www.ensembl.org/id/ENSGALT00010031605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018472.1", "url": "https://www.ensembl.org/id/ENSGALP00010018472.1" } ] } }, { "isoform_ac": "A0A8V0YIU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU5/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1552, "header": "tr|A0A8V0YIU5-1|A0A8V0YIU5_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10694816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031615.1", "url": "https://www.ensembl.org/id/ENSGALT00010031615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018482.1", "url": "https://www.ensembl.org/id/ENSGALP00010018482.1" } ] } }, { "isoform_ac": "A0A8V0YQP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP3/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTGLPCSKDQLSIHFCQRLRGIGKCLVPSIQLQCCFTCSHPRIRNKARYWDQQGLKQQYYTKSRRKSPRNQENNSQAAQH", "length": 1532, "header": "tr|A0A8V0YQP3-1|A0A8V0YQP3_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10694816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031625.1", "url": "https://www.ensembl.org/id/ENSGALT00010031625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018491.1", "url": "https://www.ensembl.org/id/ENSGALP00010018491.1" } ] } }, { "isoform_ac": "A0A8V0YQQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ9/entry", "sequence": { "sequence": "MPCVPPSWAASGSFWLLVLHVPALLCGTGASLFPDGRQGQFIKTLQEYEVVDPARVDANGHFVSFNLHHHISNTRKRRDLGKKENVVYYKINHKEKDLFFNLTIHMGFLSHNYIVERRRGNHSRAKIAMHSGVPCHFIGSVLQPGSGSGTAAISTCNGLTGYFHLPHGDYFIEPIKKHLQKKGTPQPHIIYEANTLPNALRRRRAVPVEEEQACGVNDTLSFFKQEDHRREKWEQNHVAVRKVSRRSVSKERWVETLVVADSKMVEYHGSDHVESYILTIMNMVTGLFHDPSIGNAIHIVLVRLILFEEEEQGLKIVHHADKTLASFCKWQKSVNPKSDVNPTHHDVAVLLTRKDICAGMNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGKRPYIMSRQLQYDPTPLTWSQCSKEYITRFLDRGWGFCLDDIPQKEVLKSPVIAPGVIYDVHHQCQLQYGSNATFCEDVDNLCQTLWCSVKGSCRSKLDAAADGTRCGENKWCFSGECITVGKTPEAIHGGWGVWSPWSHCTRTCGAGVQSAERPCDNPEPQFGGDYCTGERKRYRMCNISPCRKGLPTFRQMQCTEFDTVPYQNEFYHWVPVYNTANPCELHCRPIDHHFSEKMLDAVTDGTPCFEGRHSRDICINGMCKAVGCDYEINSNATEDQCGVCLGDGSACHTVKMTFNQSEGSGYVDIGLIPKGARGIRVTEVAEAGNFLAVRSKDPEKYYLNGGFIIQWNGEYKVAGTVFQYDRTGDLENLTAPGPTNESIWIQLLFQETNPGIKYEYTVRKEENNENEIGEPEYFWQYGEWTACTVTCGRGVRRQIAHCMRKGGGVIKNSFCDPATQPNGRQKKCYEKDCPPRWWAGEWQKCSTTCGPTGQKKRTVLCIQTVGSDEQALAVTECQHLLKPKTHQSCNRDVLCPSDWTVSNWTECTVTCGGGIRTRSVTCAKNSHEPCDSSKRPNSKALCGLQQCPSARRFLIPPLAPKRGKIIIRKTTNPKWSPPRRIPVPSPRFHTTTGVPKPESVTPSPTSSGLGKIPQKEETDNATLENSFAVSTDVYNYPVFSTENSFHQNTTLWPFPSSLGTEIIKHAEKISKSETVSTVEGELQRSEDTPVSSFTSSPEITSNYDYLTEESDDVDGSTEGSEKPTDRLYSTEHNLEIRTSSTTQDTNSPIFQNGDVTSDPPPSSHPQEPSMPPPDSRAGQGLTFPTTASSTSLQVDVPIREVTTQEAVTEVPTTFGNVLRGQADSRTEMKLPDNITSSTQLLVNKHALKNHMETSERILMNVTESSLLITSSSLPGDAYWIVGNWSECSTTCGMGAFWRHVECSSKNVSHCQHTKKPDHARKCYLRPCASWKTGNWSKCSAYCNGGFKTRDVQCIDVREKQLLRPFHCQLLGYKPQLTTSCNTEPCLQWRVEPWNECTVSCGGGIQQRTVKCRNIETDETEDDNMCVKKPKPTEHQQCNQQECRKNTENPTQR", "length": 1508, "header": "tr|A0A8V0YQQ9-1|A0A8V0YQQ9_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 12 OS=Gallus gallus OX=9031 GN=ADAMTS12 PE=4 SV=1 CANONICAL=A0A8V0YIS9-1" }, "locus": { "chromosome": "Z", "start_pos": 10862881, "end_pos": 10663394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031642.1", "url": "https://www.ensembl.org/id/ENSGALT00010031642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018506.1", "url": "https://www.ensembl.org/id/ENSGALP00010018506.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Thr", "end_pos": 1057, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1057", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1061, "start_aa": "Thr", "end_pos": 1061, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1061", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427428", "resource": "KEGG Pathway" }, { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTJ3-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 12", "gene_name": "Adamts12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCAQGNWMAKLSMVAQLLNFGAFCHGRQAQPWPVRFPDPKQEHFIKSLPEYHIVSPVQVDASGHFLSYGLHHPVTGSRKKRAAGGSGDQVYYRISHEEKNLFFNLTVNWEFLSNGYVVERRYGNLSHVKMAASSGQPCHLRGTVLQQGPTIRMGTAALSACQGLTGFFHLPHGDFFIEPVKKHPLTEEGYQPHVIYRRQSYRVPETKEPTCGLKDSLDNSVKQELQREKWERKNWPSRSLSRRSISKERWVETLVVADTKMVEYHGSENVESYILTIMNMVTGLFHNPSIGNAVHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLITRKDICAGVNRPCETLGLSQLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSQQIQYDPTPLTWSKCSKEYITRFLDRGRGFCLDDVPRKKGLKSNVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTRCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGAQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSDTPTFRQMQCSEFDTVPYKNQFYRWFPVFNPAHPCELYCRPIDEQFSERMLEAVIDGTPCFEGGNSRNVCINGICKRVGCDYEIDSNATEDRCGVCLGDGSACQTVKKVFRQKEGSGYIDIGLIPKGARDIRVMEIKAAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLERLMAPGPTNESVWLQLLFQVTNPGIKYEYTVRKDGLDNDVEKLLYFWQFGRWTECSVTCGTGIRRQTAHCVKKGHGIVKTTFCNPETQPSVRQKKCYEKDCPPRWWAGEWEACSMTCGPYGEKKRTVLCIQTMGSDEQALPATDCQHLLKPKTLVSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNLNEPCDKTRKPNSRALCGLQQCPFSRRVLKPNKDTVPSGKNPTTSEHDHFKPIPASTSRPTPLSTPTVPESVSTSTPTINSLGSTITSQEEPDGIGWQNNSTQAEEDSHIPTSVGSTSQTPLTSWSWSMQPDDENVSSSAIGPTSESDFWATTSDSGLSSSNAMTWQVTPFYSTATTEPEVEIHSGSGEDSDQPLNKEENNSVLWNKIRVPERDAPMEMDAEIPLGPPPTSYVTEESSWPPFSTMMKSSLPAWSFKNETPRDEGMITEKSGNIPLPLGGDHQTTSPEKLGNNDQLASANSTNPTQGSGPVLTEEDASTLIEEGFLLNASNYKHLMKDHSPAHWIVGNWSKCSTTCGLGAYWRSVECSTGMNADCAAIQRPDPAKKCHLRPCAGWRVGNWSKCSRNCSGGFKIREVQCMDGVDHHRSLRPFHCQFLAGVPPPLSMSCNLEPCEEWKVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPASTVPCNRHLCCHWATGNWELCTTSCGGGSQKRTVHCIPSENSTTEDQDQCFCDHQARPPEFQNCNQQACRKSADLTCTKDRLSTSFCQTLKSMKKCSVPSVRVQCCLSCPQTQSIHTQRQRKQQMLQNHDTL", "length": 1599 }, "evidence": [ { "id": "A0A8V0YIS9", "url": "https://omabrowser.org/oma/group/A0A8V0YIS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MXQ0-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif 12", "gene_name": "ADAMTS12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPCAQRSWLAKLSVVAQLLNLGALCYGRQPQPGPVRFPDKRQEHFIKALPEYHVVAPVRVDASGRFLSYGLHHSVSNGRRKRDLDDPEGRVYYRISHHEKDLFFNLTVNQGLLSKNYIVERRYGNLSRVKMEASSGPPCHLRGTVLQQGTRVGTAALSTCHGLTGFFHLPHGDFFIEPVKNHPLAEGEYHPHVVYRRQRRGVPEMKDPTCGLKDSPGTSQKQELLREKWERSHLRGRSLSRRSISKERWVETLVVADTKMIEYHGRENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPAHHDVAVLLTRKDLCAGVNHRCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTVAHELGHSFGIQHDGKENDCEPLGRHLYIMSRQLQYNPAPLTWSKCSKDYITRFLDRGWGFCLDDIPQKKGLKSNIIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGAQSAERLCNNPEPKFGGKYCTGERKRYRLCNIHPCRPDTPTFRQMQCSEFDTVPYRNAFYHWFPVFNPARPCELYCRPIDGHFSEKMLDAVIDGTPCFEGGNSRNVCINGMCKMVGCDYEIDSNATEDRCGVCLGDGSACQTVKKMFKQKEGSGYVDIGLIPKGARDIRVMEVEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTIFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPGIKYEYTVRKDGLDNDVEKLVYFWQYGRWTECSVTCGTGIRRQTAHCVKKGRGIVKATFCDPETQPNGRQKKCHEQDCPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMGSDEQALPTQDCQHLLKPKTLVSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDMTRKPNSRALCGLQQCPSSRRILKPNRGTIFSGKKLPTPDPFKPVPPTTPSPRTLTTPSPRVLTSPTVPGPLSTSTPTMNSPGPTTASKEGDLDGKQGQNSSIQTELDTHNVISTGSTSQPILTSWSLSIQPNEENVSNPDTGPTSEGDLVIMTTSGSDSSTSSNAMTWQVTSFYSPLTKEPEMEIHSGSGEGSEPSEKKNENNSVTWTKIRVPGNDAPGERSTEIPLGPPPTPYLGGESLWPLFSTVSEGLVPSQRPITLKNGTSRAKGTVTEKPANTPLPLGEDHQPAYSKKPVNPHPTELPSNMNLTQSSGPVLTKEDATSLMAEGFLLNASDYKHLSMGRSPAYWIVGNWSECSTTCGLGTYWRSVQCSTHVDSDCATLQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFQIREIQCVDSRDHRSLRPFHCRFLAGLPPPLTTSCNLEPCEEWQVEPWSQCSSSCGGGVQKRGVTCPGLCDWTERPTSTTPCSGQPCCHWAAGNWDPCTVSCGGGFQKRTVHCVASENNKTEGQDQCLCDHERRPPEFQKCNPQACRKNADLLCIKDNLSASFCQTLKTMKKCSVPTVRAQCCLSCSQTHVAHTQRPRKRQPLKNPKAP", "length": 1607 }, "evidence": [ { "id": "A0A8V0YIS9", "url": "https://omabrowser.org/oma/group/A0A8V0YIS9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P58397-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "gene_name": "ADAMTS12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDWVYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTGFFQLPHGDFFIEPVKKHPLVEGGYHPHIVYRRQKVPETKEPTCGLKDSVNISQKQELWREKWERHNLPSRSLSRRSISKERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSRQLQYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGICKMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFKQKEGSGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPELSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITWPVTPFYNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPFSTVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDHQPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWIVGNWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSVPTVRAECCFSCPQTHITHTQRQRRQRLLQKSKEL", "length": 1594 }, "evidence": [ { "id": "A0A8V0YIS9", "url": "https://omabrowser.org/oma/group/A0A8V0YIS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q811B3-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 12", "gene_name": "Adamts12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPCARGSWLAKLSIVAQLINFGAFCHGRQTQPWPVRFPDPRQEHFIKSLPEYHIVSPVQVDAGGHVLSYGLHHPVTSSRKKRAAGGSGDQLYYRISHEEKDLFFNLTVNWEFLSNGYVVEKRYGNLSHVKMVASSGQPCHLRGTVLQQGTTVGIGTAALSACQGLTGFFHLPHGDFFIEPVKKHPLTEEGSYPHVVYRRQSIRAPETKEPICGLKDSLDNSVKQELQREKWERKTLRSRSLSRRSISKERWVETLVVADTKTVEYHGSENVESYILTIMNMVTGLFHSPSIGNLVHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLITRKDICAGVNRPCETLGLSQLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSQQIQYDPTPLTWSKCSKEYITRFLDRGRGFCLDDIPSKKGLKSNVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTRCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGAQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSDTPTFRQMQCSEFDTVPYKNQFYRWFPVFNAAHPCELYCRPIDEQFSERMLEAVIDGTPCFEGGNSRNVCINGICKRVGCDYEIDSNATEDRCGVCLGDGSACQTVKKLFRQKEGSGYVDIGLIPKGARDIRVMEIKAAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLIAPGPTNESVWLQLLFQVTNPGIKYEYTVRKDGLDNDVEKLLYFWQFGRWTECSVTCGTGIRRQAAHCVKKGHGIVKTTFCNPETQPSVRQKKCHEKDCPPRWWAGEWEACSTTCGPYGEKKRTVLCIQTMGSDEQALPATDCQHLLKPKALVSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNLNEPCDKTRKPNSRALCGLQQCPFSRRVLKPNKDIAPSGKNQSTAEHDPFKPIPAPTSRPTPLSTPTVPESMSTSTPTINSLGSTIASQEDANGMGWQNNSTQAEEGSHFPTSSGSTSQVPVTSWSLSIQPDDENVSSSAIGPTSEGDFWATTTSDSGLSSSDAMTWQVTPFYSTMTTDPEVEIHSGSGEDSDQPLNKDKSNSVIWNKIGVPEHDAPMETDAELPLGPPPTSYMGEEPSWPPFSTKMEGSLPAWSFKNETPRDDGMIAEKSRKIPLPLAGDHHPATSEKLENHDKLALPNTTNPTQGFGPVLTEEDASNLIAEGFLLNASDYKHLMKDHSPAYWIVGNWSKCSTTCGLGAYWRSVECSSGVDADCTTIQRPDPAKKCHLRPCAGWRVGNWSKCSRNCSGGFKIREVQCMDSLDHHRSLRPFHCQFLAGAPPPLSMSCNLEPCGEWQVEPWSQCSRSCGGGVQERGVSCPGGLCDWTKRPATTVPCNRHLCCHWATGNWELCNTSCGGGSQKRTIHCIPSENSTTEDQDQCLCDHQVKPPEFQTCNQQACRKSADLTCLKDRLSISFCQTLKSMRKCSVPSVRAQCCLSCPQAPSIHTQRQRKQQLLQNHDML", 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"ENSGALT00010028903.1", "url": "https://www.ensembl.org/id/ENSGALT00010028903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016662.1", "url": "https://www.ensembl.org/id/ENSGALP00010016662.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": 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"MPAGLAAGGSECWRLRAGRSLAVCASTLLCSRPVEGSVFMETSHCPGLLSLLQCWALPWWPPVTMGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVLVMSLTIFMMLMNGLAQLLTTKRLELSRRTKHHSM", "length": 997, "header": "tr|A0A8V0YKZ7-1|A0A8V0YKZ7_CHICK Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCQ8/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKPFPHCSCDFRHYGFALFLFG", "length": 856, "header": "tr|A0A8V0YCQ8-1|A0A8V0YKZ7_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68150116, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028951.1", "url": "https://www.ensembl.org/id/ENSGALT00010028951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016710.1", "url": "https://www.ensembl.org/id/ENSGALP00010016710.1" } ] } }, { "isoform_ac": "A0A8V0YCR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR3/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALH", "length": 876, "header": "tr|A0A8V0YCR3-1|A0A8V0YKZ7_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68159431, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028957.1", "url": "https://www.ensembl.org/id/ENSGALT00010028957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016716.1", "url": "https://www.ensembl.org/id/ENSGALP00010016716.1" } ] } }, { "isoform_ac": "A0A8V0YDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY0/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKLCICHVRSSISTVFSSGLAEVFIISAKKGLNEVRIIRVF", "length": 875, "header": "tr|A0A8V0YDY0-1|A0A8V0YKZ7_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68145084, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028939.1", "url": "https://www.ensembl.org/id/ENSGALT00010028939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016698.1", "url": "https://www.ensembl.org/id/ENSGALP00010016698.1" } ] } }, { "isoform_ac": "A0A8V0YG41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG41/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVSNCTFVKFSQRTV", "length": 850, "header": "tr|A0A8V0YG41-1|A0A8V0YG41_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68144075, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028935.1", "url": "https://www.ensembl.org/id/ENSGALT00010028935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016694.1", "url": "https://www.ensembl.org/id/ENSGALP00010016694.1" } ] } }, { "isoform_ac": "A0A8V0YG51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG51/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSPCDSSVAFLLQRCLLLL", "length": 910, "header": "tr|A0A8V0YG51-1|A0A8V0YG51_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68151980, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028945.1", "url": "https://www.ensembl.org/id/ENSGALT00010028945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016704.1", "url": "https://www.ensembl.org/id/ENSGALP00010016704.1" } ] } }, { "isoform_ac": "A0A8V0YG66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG66/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKRLWKLA", "length": 866, "header": "tr|A0A8V0YG66-1|A0A8V0YG66_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68150137, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028961.1", "url": "https://www.ensembl.org/id/ENSGALT00010028961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016720.1", "url": "https://www.ensembl.org/id/ENSGALP00010016720.1" } ] } }, { "isoform_ac": "A0A8V0YKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW7/entry", "sequence": { "sequence": "METSHCPGLLSLLQCWALPWWPPVTMGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSISHYVLVMSLTIFMMLMNGLAQLLTTKRLELSRRTKHHSM", "length": 926, "header": "tr|A0A8V0YKW7-1|A0A8V0YKW7_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68159549, "end_pos": 68067343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028943.1", "url": "https://www.ensembl.org/id/ENSGALT00010028943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016702.1", "url": "https://www.ensembl.org/id/ENSGALP00010016702.1" } ] } }, { "isoform_ac": "A0A8V0YKY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY8/entry", "sequence": { "sequence": "MGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVLVMSLTIFMMLMNGLAQLLTTKRLELSRRTKHHSM", "length": 913, "header": "tr|A0A8V0YKY8-1|A0A8V0YKY8_CHICK Computationally mapped isoform of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68159549, "end_pos": 68067723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028969.1", "url": "https://www.ensembl.org/id/ENSGALT00010028969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016728.1", "url": "https://www.ensembl.org/id/ENSGALP00010016728.1" } ] } }, { "isoform_ac": "A0A8V0YKZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7/entry", "sequence": { "sequence": "MPAGLAAGGSECWRLRAGRSLAVCASTLLCSRPVEGSVFMETSHCPGLLSLLQCWALPWWPPVTMGVPVFILAGLLVHFVFLASIFDIYFSSPLVHGMTPQQTPLPPPAKRLVLFVADGLRADSLFELNSNNTPQAPYLRAILENNGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESKHTWSWGSPDILPMFAKGATGDHVYTFCYTAESEDFGAQDAAELDTWVFDHVKSFFNSSRSNQTLFSALNEEKVVLFLHLLGIDTNGHAHRPYSKEYKENIRKVDEGVEEIVSMLESFYGNDGKTAYILTSDHGMTDWGSHGAGHPSETLTPLIAWGAGVNYPQEVTSQLFEDNFLKEWKLENLKRMDVNQADIAPLMASLIGVPFPLNSVGTLPLEYLNNSDHFKAESMFTNAVQVLEQFKVKMSQKKRTTLSFLFTPFKPLSDSEQINFLKKARLYIQQQKYSEAVSLCKTLINLALEGLSYYHTYDRLFLGLSIAVSFVGWTTYVILVIIKTHTNLIKAAQINNKESTGPLYSFMFAGMIIAFFLLIQASPWTYYVYCLLPVPIWYAVVRELHVIQDLAANLWSLPVGHSVGFLLICILGIELLVFSFFYRSTLTVGLLVFAGWPVITQMWVQAKRTTLIWTLLCVFLAVFPLMPVVGREPNIPLVIVAGLTTLLISCFSLASFSRSENKYRGKEDLKVYFYQMFSIALSTYVVSSTHNSLKNKQGLPVFNQIVSWMTLASSSALPLLSPTLLFQRLFSILLSLMATYLLLSTGYEALFPLVLSGLMLVWIQMEQEALQHYGLSLRSKLAVFNFAYATDITQFRQLHLDDIRRSFFFVFFIVTAFFGTGNIASVNSFDPASVYCFLTVFSPFMMGGLLLLKVVIPFVLVSCAFEAVQVTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVLVMSLTIFMMLMNGLAQLLTTKRLELSRRTKHHSM", "length": 997, "header": "tr|A0A8V0YKZ7-1|A0A8V0YKZ7_CHICK Isoform 1 of GPI ethanolamine phosphate transferase 1 OS=Gallus gallus OX=9031 GN=PIGN PE=3 SV=1 CANONICAL=A0A8V0YKZ7-1" }, "locus": { "chromosome": "2", "start_pos": 68159549, "end_pos": 68057357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028979.1", "url": "https://www.ensembl.org/id/ENSGALT00010028979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016738.1", "url": "https://www.ensembl.org/id/ENSGALP00010016738.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1I9LQ21-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLVGELGRSMRSDGILGVGGSDQSRATAVVVASRRRWLKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVQKKDSGKVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVVTSGAIIIVISLAAKWLDTHAEGNKFWQSITFHESRTQMCSMLYCIQIFLVGVSSVMVFLSTKHRTQNQELHSSHQFINWLVAGSSMVLPLFSANGILSRLSSIFLGFAPPFLLLSIGYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRSIRIKPLSTSPSLKTL", "length": 1001 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8C2M2G6-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLLFFALGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADALYGLDEDGNSSAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAQDATKLDTWVFDKVKDFFDAARNNQSLFSKVNEEKIVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSVFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKFPEKVSAQQFDDKFLKEWKLENWKRRDVDQADIAPLMASLIGVPFPLNSVGTLPVDYLNNTGLFKAESMLTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALKGLSYYHTYDRFFLGISVASGFVGWTSYASLLILKSHSNFTRSSRKEVKKPHYLLLCSFVAIGVLVVCFLLIQVCPWTYYVYCLLPVPIWYAVLREYQVIQDLVASLLTFPPSHFVAHLLVFILGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQPWTQAKITYLSWALFSLLLAVFPLMPVVGRKPDLSLVMGAGLLVLLLALAIVTVLTKRKITLVKEELLVLLLQVLSTVLSMYVVYSTHHSLLEKEGLPLMNQIVSWTTLASSLVVPLLSSTILFQRLSSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLHQPGVSCKQKLTSIQFTCNTDIAQLRLLDLDDVRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLIVLVISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLL", "length": 931 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LNZ1-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLFFALGLLVHFVFFASIFDIYFTSPLVHGMTPQVTPLPPPAKRLVLFVADGLRADALYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFSIVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYEDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYEDEFLKEWRLENWKRQDINQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDDVVSLCEELIDLALRGLSYYHTYDRLFLGISVAVGFVGWTSYASLLIIKSHSDIPRGTRREGKKPHHLLPCSFIVAGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLKEREVIQALVESLLAFPLSRFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITCLSWAFFSLLLAVFPLMPVVGRKPDLSLVMGAGLLVLLLSLAVLATLVKRKLNLVKDELLVLLLQVLSTVLSMYVVYSTHHSLLKKEGLPLLNQIVSWATLASSLVVPLLSPTALWQRLTSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIHVEQETLQQSGVSCKQKLASIQFTYNTDITQFRQLCLDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLVISDIMALHFFFLVKDSGSWLDIGTSEKWIGKVGQENVAKASLQ", "length": 909 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z838-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIG-N", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFFEENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGAHGSGSPHETDTPFMLWGAGASRAVPKPGGRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENFQWKSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSARAERSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVMLVIFYTAKQLLRVIPWEEIDFKMLPLRLIHWDVISAKHH", "length": 894 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E1BM45-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIGN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLYITLGLLVHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLMLFVADGLRADKLYELDEDGNSRAPFVRNIIMNEGSWGISHTRVPTESRPGHVAMIAGFYEDVSAVAKGWKENPVEFDSLLNETRYTWSWGSPDILAMFAKGDLRSHIFTESYDASSEDFGAHDVTKLDTWVFDHVKEFFHAARNNQSLFSKVNEDKIVFFLHLLGIDTNGHAHRPSSREYSDNIKLVDKELKEIESTVKDFYGNDGKTAFIFTADHGMTDWGSHGAGHPLETCTPFIAWGAGIRLPQKVSAQKFDDSYLQEWKLENWKRQDINQADVAPLMAALIGVPFPLNSVGIIPVDMLNTSDLFKAESMFTNAVQILEQFKVKMTQKKEATLSFLFTPFKSLSDTKQANILRKARYYIKQKKYDEAVSLCRQLIHLALRGLAYYHTYDRFFLAFNVVLGFVGWTSYASLLIIKSHCNLMRGVSTEAKNPSRLLPCAFGAVGVSVTFFLLIQACPWTYYVYCLLPLPIWYAVLREIPVIQGFVTLLSTFPPRRFLGYLLLFILGVEVLVLSFFYRYMLTAGLVALAAWPFITALWTRAKSISLSWIFFCLLLAVFPLMPVVGRKPDIFLVVGAGLLVLLLSLFVVTSVIKRKDSFINEELVLHLLQMLSVMFSMCVVYGTHHSLLKKQGLPLLNQIVSWTILASSFVMPLLSPPVLFDRLFSILVSSMSTYLLLSTGYEALFPLVLSCLMFVWIHMEQETLQHSVVSCKQKVSTIQFACNTDAAQCRDLCLDDIRRAFFLVFFLVTAFFGTGNIASVNSFDPSSVYCFLTVFSPFKMGALIMWKILIPFVLVMCAFEAVQVTTQLSSKSLFLMVINISDIMALHFFFLIKDYGSWLDIGTSISHYVIVMSMTIFMVFLNCLAQMLTTRKLSLCGRPKSHVI", "length": 931 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7EXW2-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "pign", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMVTFFVVGLIVHVVFFLCIFDIYFTSPLVHGMTPQRVSLPPPAKRLVLFVADGLRADSLFKPDDSGTSRAPYLRSVIEEGGTWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESRYTWCWGSPDILPMFAKGATGDHVYTHTYPPEREDFASTDASRLDTWVFDEVKDFLTAAKSNETLLKKLHEEQNVFFLHLLGIDTNGHAHRPMSKECLENIGLVDAGVADIVTVMDDFYGHDGKTAYVFTSDHGMTNWGSHGAGHPSETLTPLVVWGAGVQKAQWETSQKYEDNYLKEWGLESYRRVDVNQADIAPLMSSLIGIPFPLNSVGVLPLSYLNNSQHFKAESMYANAIQILEQFRVKLAQKKETTISFLFTPYQPLTDSKQVDFIRQARDLIQKGRFDEAIVYCKDLIAQAMEGLSYYHTYDRLFLGSSVVLGFIGWTSYVVLYILKTHASLRKPPTNTSMVTERLLGWGFLCVGLLMALFLLVQSSPWSYYIYSLMPVAVWYAVLKEFKTLVGLVRSIPSLPLTKCFGYFVLVAFGIELLVMSFFYRAMLSLGLVVLALWPVVSGFYTKAKFKSLSWTLSCLSLAVFPLLPVVGREPNINYVISAGGLILFNSSSFLWSSWRDSPLMRRDRQLFIFQMVQVALCAYTLTSTHSSLQLKQGLPIFNQLVSWSTLVSSFLIPLLSSTRLFHRLLSILMSLTCVYLLLSTGHEALFPLMLSWLMLAWIHIEQEAMSRQGSSNRNELSCIDFAENIDITKVRQLRLDDIRKSYFFVFFIIIAFFGCGNIASINSFDPASVYCFLTVFNPFIMGGLLMWKVLIPFVIVMCTFESIQVSTQLSSRSLFLIVLVISDLMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLMLLSVMTHILTSKKILLGRSRKMHFR", "length": 932 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95427-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "PIGN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM", "length": 931 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36051-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "MCD4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDKTKKTQ", "length": 919 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WY9-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "pigN", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYHIISSNINNINNKSNKPNDNKNDKTKFNSKILVIVLIGIIFHAVFTLSIFDIYFRSPLVHGMTPHPINLPAPAKRLVLFVADGLRADKFFEIDENTGKSRSPFLRNIIENKGTWGISHTRVPTETRPGHVALIAGFYEDVSAVTKGWKANPVEFDHLFNETTYSFGYGSPDVLPMFSEGVPHMQSESYPEEAEDFASDASKLDTWVFDKVQQLLLNASTNDQELNRKLRSDKVSIFLHLLGLDTNGHAYRPNSKEYFDNIALVDRGIEKIVKLIEDFYGNDGKTAFVFTADHGMSNRGSHGDGERANTETPLVVWGSGVRGPLSSDLQMERIASLRGKAKEMLPVNVETPTNWKLSSLFRSDVSQADIAPLMTSLLGVPSPLNSVGVLPTEILSEDTPQYTTAALRANTLQIWEMYKIKSSSKQQSTLIFFSPFTKLSDADRMFERIEQHISLSQWEDAQILCHQMIDLCLMGLNYFQTYDRPFLMTVITMGYFGWIITLSLYVLNNYTSIGIENCNQQKLSTQMKRFKTLSNYLIFIESIALVGFLLATDAPLLYYLYCVFLVLFWAKTIPSNIVPLYIFICDSFSQVSSTRGHFINTNNSANLSIIKNFIILSVSAISVMELLVVSYFHRGVLSLLYQILGVVSVFFFYNRSGAGKTSTLLKSLWLISCLLMSIFPSLPIDYGSDTKLVCFGGILISILGVLTSLFKFRNNSKQQQQSSSSSQQKLQKSKKNQIINSILIISILLSSFIVYTTDSSLEKKIGLPFINQLLSWILLVSGVLILAIYRGKGFYDHWTFLCLSLSIPFLLLSISYEVLFFGNLILNLTLWMYFELKVDNDHTIPKLVSITPNSEPSTSLSFSKSASKSNLMNITQHDIRRAIFYIFFCYVGFFGVGNIASISSFEISSTYRFTTIFRPFLMGALLLVKIFIPLLLVAISFSLLNNNLNVPRPGSFLIVIALTDIMSINFFFLVKDTGSWLEIGVSISHYAISNAFIILQLLLFAVSALLVPTTLKYINNNSNNNNNTIKSK", "length": 1032 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9R1S3-1", "protein_name": "GPI ethanolamine phosphate transferase 1", "gene_name": "Pign", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLM", "length": 931 }, "evidence": [ { "id": "A0A8V0YKZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8855659" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKZ7-1" ], "evidence": [ { "id": "R-GGA-162798", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162798" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8855659", "participant_name": "mannose (a1-4) glucosaminyl-acyl-PI [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "53056", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKZ7", "gene_name": "PIGN", "activity": [ { "ec_number": "2.-.-.-", "activity": "", "evidence": [ { "id": "A0A8V0YKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ7" }, { "id": "PF04987", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04987" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI ethanolamine phosphate transferase 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 496, "end_pos": 950, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 416, "end_pos": 418 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIM0-1", "uniprot_ac": "A0A8V0YIM0", "uniprot_id": "A0A8V0YIM0_CHICK", "mass": { "chemical_mass": 22202.0, "monoisotopic_mass": 22202.0 }, "refseq": {}, "gene_names": [ { "name": "SAR1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAR1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0", "locus": { "chromosome": "13", "start_pos": 15356715, "end_pos": 15342187, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013254", "url": "https://www.ensembl.org/id/ENSGALG00010013254" } ] } } ], "crossref": [ { "id": "A0A8V0YIM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00879", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00879", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YCZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIL5", "url": "https://www.orthodb.org/?gene=A0A8V0YIL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIM0", "url": "https://www.orthodb.org/?gene=A0A8V0YIM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8963888", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8963888", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPKELTIAGMTFTTFDLGGHAQARRVWKNYLPAINGIVFLVDCADHDRLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGNIPLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "length": 196, "header": "tr|A0A8V0YIM0-1|A0A8V0YIM0_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=SAR1B PE=1 SV=1 CANONICAL=A0A8V0YIM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ5/entry", "sequence": { "sequence": "MGEERGVPEFCFEFRLKDSDMSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHAQARRVWKNYLPAINGIVFLVDCADHDRLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGNIPLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "length": 218, "header": "tr|A0A8V0YCZ5-1|A0A8V0YIM0_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=SAR1B PE=1 SV=1 CANONICAL=A0A8V0YIM0-1" }, "locus": { "chromosome": "13", "start_pos": 15352890, "end_pos": 15346402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031858.1", "url": "https://www.ensembl.org/id/ENSGALT00010031858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018662.1", "url": "https://www.ensembl.org/id/ENSGALP00010018662.1" } ] } }, { "isoform_ac": "A0A8V0YIL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL5/entry", "sequence": { "sequence": "MSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTRRVWKNYLPAINGIVFLVDCADHDRLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGNIPLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "length": 176, "header": "tr|A0A8V0YIL5-1|A0A8V0YIM0_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=SAR1B PE=1 SV=1 CANONICAL=A0A8V0YIM0-1" }, "locus": { "chromosome": "13", "start_pos": 15352890, "end_pos": 15346691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031862.1", "url": "https://www.ensembl.org/id/ENSGALT00010031862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018666.1", "url": "https://www.ensembl.org/id/ENSGALP00010018666.1" } ] } }, { "isoform_ac": "A0A8V0YIM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0/entry", "sequence": { "sequence": "MSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPKELTIAGMTFTTFDLGGHAQARRVWKNYLPAINGIVFLVDCADHDRLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGNIPLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID", "length": 196, "header": "tr|A0A8V0YIM0-1|A0A8V0YIM0_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=SAR1B PE=1 SV=1 CANONICAL=A0A8V0YIM0-1" }, "locus": { "chromosome": "13", "start_pos": 15352890, "end_pos": 15346691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031867.1", "url": "https://www.ensembl.org/id/ENSGALT00010031867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018671.1", "url": "https://www.ensembl.org/id/ENSGALP00010018671.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" }, { "id": "R-GGA-8963888", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8963888", "resource": "Reactome", "description": "Chylomicron assembly" }, { "id": "R-GGA-983170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983170", "resource": "Reactome", "description": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "regulation of lipid transport", "id": "GO:0032368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "COPII vesicle coating", "id": "GO:0048208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "regulation of COPII vesicle coating", "id": "GO:0003400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "cellular response to leucine starvation", "id": "GO:1990253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "lipid export from cell", "id": "GO:0140353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "amino acid sensor activity", "id": "GO:0140785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-174587", "name": "nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-174587", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174587" } ] }, { "id": "R-GGA-203973", "name": "Vesicle budding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "COPII-coated ER to Golgi transport vesicle, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNR7-1", "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-203973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203973" } ] }, { "id": "R-GGA-203977", "name": "SAR1 Activation And Membrane Binding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-203977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203977" } ] }, { "id": "R-GGA-203979", "name": "Coat Assembly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-203979", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203979" } ] }, { "id": "R-GGA-5694417", "name": "SEC16 complex binds SAR1B:GTP:SEC23:SEC24", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNR7-1", "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-5694417", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694417" } ] }, { "id": "R-GGA-5694522", "name": "Inner coat assembly and cargo binding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNR7-1", "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-5694522", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694522" } ] }, { "id": "R-GGA-5694527", "name": "Loss of SAR1B GTPase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNR7-1", "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-5694527", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694527" } ] }, { "id": "R-GGA-983422", "name": "Disassembly of COPII coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, ER to Golgi transport vesicle membrane", "input_participant_list": [], "output_participant_list": [ "R-GGA-203972", "R-GGA-203981", "R-GGA-203983" ], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-983422", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983422" } ] }, { "id": "R-GGA-983424", "name": "Budding of COPII coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum lumen, endoplasmic reticulum membrane, ER to Golgi transport vesicle membrane, lumenal side of endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-983424", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983424" } ] }, { "id": "R-GGA-983425", "name": "Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIM0-1" ], "evidence": [ { "id": "R-GGA-983425", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983425" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-203972", "participant_name": "SEC23A [cytosol]", "crossref": [ { "id": "XP_040528624.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010006343", "database": "ENSEMBL", "url": "" }, { "id": "XP_046775062.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010015134", "database": "ENSEMBL", "url": "" }, { "id": "XP_040528625.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010008895", "database": "ENSEMBL", "url": "" }, { "id": "XP_421250.1", "database": "RefSeq", "url": "" }, { "id": "A0A1D5P0E2", "database": "UniProt", "url": "" }, { "id": "XP_046775061.1", "database": "RefSeq", "url": "" }, { "id": "XP_040557911.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-203981", "participant_name": "SEC13 [cytosol]", "crossref": [ { "id": "ENSGALP00010033312", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0ZWR5", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010022642", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010055088", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-203983", "participant_name": "SEC31A [cytosol]", "crossref": [ { "id": "A0A8V0XFB2", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010005382", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010009092", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010003925", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": "A0A8V0Y4A4", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R6", "gene_name": "RAP1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] } ] }, { "uniprot_ac": "A0A8V0YA62", "gene_name": "RAB28", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] } ] }, { "uniprot_ac": "A0A8V0YDI7", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] } ] }, { "uniprot_ac": "A0A8V0YIU8", "gene_name": "GTPBP1", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] } ] }, { "uniprot_ac": "A0A8V0YTL7", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] } ] }, { "uniprot_ac": "A0A8V0YTY9", "gene_name": "EIF5B", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJI3-1", "uniprot_ac": "A0A8V0YJI3", "uniprot_id": "A0A8V0YJI3_CHICK", "mass": { "chemical_mass": 140292.0, "monoisotopic_mass": 140292.0 }, "refseq": { "ac": "XP_040518473", "name": "phospholipid-transporting ATPase IH isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518473" }, "gene_names": [ { "name": "ATP11A", "type": "recommended", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] }, { "name": "ATP11A", "type": "synonym", "evidence": [ { "id": "XP_040518473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518473" } ] } ], "protein_names": [ { "name": "Phospholipid-transporting ATPase", "type": "recommended", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3/entry#names_and_taxonomy" } ] }, { "name": "phospholipid-transporting ATPase IH isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040518473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518473" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518473" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP11A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3", "locus": { "chromosome": "1", "start_pos": 137780003, "end_pos": 137900103, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013263", "url": "https://www.ensembl.org/id/ENSGALG00010013263" } ] } } ], "crossref": [ { "id": "A0A8V0YJI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJI3", "database": 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"MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQSFSCISSILIQNNCVLLGEPSCCKRCSMSENASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1224, "header": "tr|A0A8V0YJI3-1|A0A8V0YJI3_CHICK Isoform 1 of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD23/entry", "sequence": { "sequence": "MAGGWELDGPSDLFQPRPFCEILVIFKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQKSMRHKTALNALVNSDGPLLEGTLSASSHN", "length": 1112, "header": "tr|A0A8V0YD23-1|A0A8V0YJI3_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137830664, "end_pos": 137784932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031884.1", "url": "https://www.ensembl.org/id/ENSGALT00010031884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018687.1", "url": "https://www.ensembl.org/id/ENSGALP00010018687.1" } ] } }, { "isoform_ac": "A0A8V0YD66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD66/entry", "sequence": { "sequence": "MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQLMTTNTHMMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQNASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1202, "header": "tr|A0A8V0YD66-1|A0A8V0YJI3_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137899855, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031931.1", "url": "https://www.ensembl.org/id/ENSGALT00010031931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018728.1", "url": "https://www.ensembl.org/id/ENSGALP00010018728.1" } ] } }, { "isoform_ac": "A0A8V0YD75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD75/entry", "sequence": { "sequence": "MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQTKHQCLSVEQSTIFMLSQTSSSLSF", "length": 1134, "header": "tr|A0A8V0YD75-1|A0A8V0YJI3_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137899855, "end_pos": 137787617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031938.1", "url": "https://www.ensembl.org/id/ENSGALT00010031938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018733.1", "url": "https://www.ensembl.org/id/ENSGALP00010018733.1" } ] } }, { "isoform_ac": "A0A8V0YIP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP7/entry", "sequence": { "sequence": "MIWLTNSLKCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQNASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1190, "header": "tr|A0A8V0YIP7-1|A0A8V0YIP7_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137843774, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031894.1", "url": "https://www.ensembl.org/id/ENSGALT00010031894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018696.1", "url": "https://www.ensembl.org/id/ENSGALP00010018696.1" } ] } }, { "isoform_ac": "A0A8V0YIQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ7/entry", "sequence": { "sequence": "MEQSPRTECAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQNASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1189, "header": "tr|A0A8V0YIQ7-1|A0A8V0YIQ7_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137897263, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031908.1", "url": "https://www.ensembl.org/id/ENSGALT00010031908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018706.1", "url": "https://www.ensembl.org/id/ENSGALP00010018706.1" } ] } }, { "isoform_ac": "A0A8V0YIR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR2/entry", "sequence": { "sequence": "MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQKSMRHKTALNALVNSDGPLLEGTLSASSHN", "length": 1139, "header": "tr|A0A8V0YIR2-1|A0A8V0YIR2_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137899855, "end_pos": 137784932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031913.1", "url": "https://www.ensembl.org/id/ENSGALT00010031913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018711.1", "url": "https://www.ensembl.org/id/ENSGALP00010018711.1" } ] } }, { "isoform_ac": "A0A8V0YJF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF7/entry", "sequence": { "sequence": "MIWLTNSLKWAAKRHVVTRSVLHSRMGRRIIKCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQNASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1213, "header": "tr|A0A8V0YJF7-1|A0A8V0YJF7_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137843774, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031892.1", "url": "https://www.ensembl.org/id/ENSGALT00010031892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018694.1", "url": "https://www.ensembl.org/id/ENSGALP00010018694.1" } ] } }, { "isoform_ac": "A0A8V0YJI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3/entry", "sequence": { "sequence": "MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQSFSCISSILIQNNCVLLGEPSCCKRCSMSENASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1224, "header": "tr|A0A8V0YJI3-1|A0A8V0YJI3_CHICK Isoform 1 of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137899855, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031923.1", "url": "https://www.ensembl.org/id/ENSGALT00010031923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018720.1", "url": "https://www.ensembl.org/id/ENSGALP00010018720.1" } ] } }, { "isoform_ac": "A0A8V0YLE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE2/entry", "sequence": { "sequence": "MVTDLGSCGKASKAVPFYNCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQNASRHCRDHISEFTPLACLKSPRYRSNDCSNSPARRSHSRSKKTMFTHWRGIDYSVLPSVFGYSNKHCRSSAGYRYSGSGLETSV", "length": 1200, "header": "tr|A0A8V0YLE2-1|A0A8V0YLE2_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137858505, "end_pos": 137783183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031899.1", "url": "https://www.ensembl.org/id/ENSGALT00010031899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018700.1", "url": "https://www.ensembl.org/id/ENSGALP00010018700.1" } ] } }, { "isoform_ac": "A0A8V0YLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH4/entry", "sequence": { "sequence": "MDCSLLRTLVSRYCAGEENWVDSRTIYVGHREPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLLFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRGDGTCFVTTASLDGESSHKTHYAVQDTKAFHSEQEIDALHATIECEQPQPDLYKFVGRINVYHDRNEPTARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLIVYLCILISKALINTVLKYVWQSEPFRDEPWYNQKTEPERKRNQFLQAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFLTWDEEMFDEDTGEGPLVNTSDLNEELGQIEYVFTDKTGTLTENNMEFVECCIEGHVYIPHVICNGQILHDCTGIDMIDSSPGGSGKEREELFFRALCLCHTVQVKDDDSVDGLKKSQLSRRSRIYISSSPDEVALVEGIQRLGYTYLCLKDNYMEILNRENNREKFELLEVLSFDSVRRRMSVIVKSSTGDIFLFCKGADSSIFPRVKEGKIDQIRSRVERNAVEGLRTLCVAYKKLTAEEYSNAQKMLQNAKLALQDREKKLAEVYEKIERDFILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQILELTTKKIEEQSLHDVLFDLSKTVLRHSGSLTRDSLSGLSTDMQDYGLIIDGAALSLIMKPRQDGSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGIIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYVRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHVSADTLKREPSLYRDVAKNALLRWRAFIYWTFLGVFDAVVFFFGAYFLFDNTILTSNGQLMTTNTHMMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFMIWGSLLFYIVFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLGIILLITVSLLPDVLKKVLCRQLWPTATERIQTKHQCLSVEQSTIFMLSQTSSSLSF", "length": 1142, "header": "tr|A0A8V0YLH4-1|A0A8V0YLH4_CHICK Computationally mapped isoform of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP11A PE=3 SV=1 CANONICAL=A0A8V0YJI3-1" }, "locus": { "chromosome": "1", "start_pos": 137899855, "end_pos": 137787617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031935.1", "url": "https://www.ensembl.org/id/ENSGALT00010031935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018731.1", "url": "https://www.ensembl.org/id/ENSGALP00010018731.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418749", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9T8-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP11A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRCSLVRTLVNRYCAGEEDWVDSRTVYVGHREPPPGAEAYIPQRYPDNRIVSAKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFVQHGRLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSSRADGTCHVTTASLDGESSHKTHYAVQDTKGFHSEEDIDSLHATIECEQPQPDLYKFVGRINVYNDQNDPVVRSLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNVFLVVYLCILISKALINTTLKYVWQSEPSRDEPWYNRKTEAERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVELQKFLGSYFLTWDEDMFDEEMGEGPLVNTSDLNEELGQVEYVFTDKTGTLTENNMEFKECCVEGHVCVPHAVCNGQVLPDASAIDMIDASPGASGREREELFFRALCLCHTIQVKDDDEVDGPQKSPDSGKRSAYISSSPDEVALVEGIQRFGFTYLRLKDNYMELLNRDNDIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVTEGKVDQIQSRVERNAVEGLRTLCVAYKTLIPEEYEGIRELLQDAKVALQDRDKKLAEAYEQIETDLVLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLEVTTKRLEEQSLHDVLFELSKTVLRSSASLTRDNFSGLSADMQDYGLIIDGAALSLIMKPREDGSSSNYRELFLDICRNCSAVLCCRMAPLQKAQIVKLIKLSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVAMDTLKRDPALYRDIAKNALLRWRAFIYWTLLGLFNALVFFFGAYFMFENTTVTSNGQVFGNWTFGTLVFTVMVLTVTLKLALDTHYWTWVNHFVIWGSLLFYIVFSLLWGGVIWPFLSYQRMYYVFIQMLSSGPAWLAIVLLVTVSLLPDVLKKVLCRQLWPSATERVQVPLGRGAQLGPRGGPGEAAGKVVHPMATPGAHWGPAARGAPWGGPREAAGKVVRPVLLMVTCDFTPELNVQWLDLDR", "length": 1187 }, "evidence": [ { "id": "A0A8V0YJI3", "url": "https://omabrowser.org/oma/group/A0A8V0YJI3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M9Q0D3-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "atp11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDFSTIRNLITRYCTGEENWVDSRTVYIGHKEPPPGTEAYIPQRFPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPMTSGLPLFFVITVTAIKQGYEDWIRHKADNSVNQCPVHIVQHGKVVRKQSQKLRVGDIVQVKENETFPCDLILLSTSREDGTCFVTTASLDGESSHKTYYAVQDTKAFSTAEEVDTLHATIECEQPQPDLYKFVGRINIYLDRDEPIARPLGSENLLLRGATLKNTEYIHAVAIYTGMETKMALNYQSKSQKRSAVEKSMNAYLIVYLCILISKALINTVLKYVWQADPNRDEPWYNQRTESERQRHVLIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFILWDDDMFDEEVGERPLVNTSDLNEELGQVEYVFTDKTGTLTENNMELRECCVDGHVYVPHAICNGQILPGAAGMDMIDSSPGVEGKEREELFFRALCLCHTVQVKEEETVDGIKRGIHQGKATSFYISSSPDEVALVEGMKRLGFTYLRLKDSHMEILNREDEMERFELLDVLNFDSVRRRMSVIVRSNSGEYYLFCKGADSSVFPRVVSGKVEQVRARVEHNAVEGLRTLCVAYKRLSQEEYEETCRLLTSAKLALQERDKKLAEAYDVIEKDFILLGATAVEDRLQDKAADTIESLHKAGIKVWVLTGDKMETAAATCYASKLFHRNTQILELTTKRTEEQSLHDVLFDLSRTVLRQHGSMTRDTFSGLSGDYQDYGLIIDGATLSAVLKPTQDATSNSGNYKEIFLEICRNCSAVLCCRMAPLQKAQIVKLIKASKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAITKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLMEQHINMDILKRDPSLYRDIAKNSLLTWPTFIYWTFLGVFDAVVFFFGAFFLFDNTTFTSNGQLMATNTQMMFGNWTFGTLVFTVLVFTVTLKLALDTHYWTWINHFVIWGSLLFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLIIVSLLPDVLKKVLCRALWPTTTERIQNADKLYKGHLSEFSPLTSLHAPPARKHERRGNERQNHAHRRSDSSPTKKLMCTYWGGKPDYCTFSSFLRIGENPRFSGAAYAYSAPGPETSV", "length": 1212 }, "evidence": [ { "id": "A0A8V0YJI3", "url": "https://omabrowser.org/oma/group/A0A8V0YJI3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A7K5-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDCSLLRTLVRRYCAGEENWVDSRTIYVGHKEPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADSAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDTKGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNQKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVPHVICNGQVLPDSSGIDMIDSSPGVSGREREELFFRAICLCHTVQVKDDHCGDDVDGPQKSPDAKSCVYISSSPDEVALVEGMQRLGFTYLRLKDNYMEILNRENDIERFELLEVLTFDSVRRRMSVIVKSTTGEIYLFCKGADSSIFPRVIEGKVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQDAKVALQDREKKLAEAYEQIEKDLILLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFELSKTVLRCSGSLTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPSLYRDIAKNALLRWRLFIYWTFLGVFDALVFFFGAYFMFENTTVTINGQMFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYIVFSLLWGGIIWPFLSYQRMYYVFIYMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQTVQLRDSISEFTPLASLQSRGAQGTRLLAAQCSSPSGRVVCSRWESEEYPVLPTHPGLLHKARYGCCRSSLETPT", "length": 1187 }, "evidence": [ { "id": "A0A8V0YJI3", "url": "https://omabrowser.org/oma/group/A0A8V0YJI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98196-1", "protein_name": "Phospholipid-transporting ATPase IH", "gene_name": "ATP11A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQTKSQCLSVEQSTIFMLSQTSSSLSF", "length": 1134 }, "evidence": [ { "id": "A0A8V0YJI3", "url": "https://omabrowser.org/oma/group/A0A8V0YJI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P98197-1", "protein_name": "Phospholipid-transporting ATPase IH", "gene_name": "Atp11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCSLLRTLVRRYCAGEENWVDSRTIYVGHKEPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDTKGFHTEADVDSLHATIECEQPQPDLYKFVGRINVYNDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNEKTESERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVPHVICNGQVLPDSSGIDMIDSSPGVCGREREELFFRAICLCHTVQVKDDHCGDDVDGPQKSPDAKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENDIERFELLEVLTFDSVRRRMSVIVKSTTGEIYLFCKGADSSIFPRVIEGKVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYEDACRLLQSAKVALQDREKKLAEAYEQIEKDLVLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFDLSKTVLRCSGSMTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSSGNYRELFLEICRNCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWTFLGVFDALVFFFGAYFIFENTTVTINGQMFGNWTFGTLVFTVMVLTVTLKLALDTHYWTWINHFVIWGSLLFYIAFSLLWGGVIWPFLSYQRMYYVFISMLSSGPAWLGIILLVTVGLLPDVLKKVLCRQLWPTATERTQNIQHQDSISEFTPLASLPSWGAQGSRLLAAQCSSPSGRVVCSRWESEECPVLPLHPGLPHKARYGCCRSSLEMPT", "length": 1187 }, "evidence": [ { "id": "A0A8V0YJI3", "url": "https://omabrowser.org/oma/group/A0A8V0YJI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of myotube differentiation", "id": "GO:0010831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010831", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "phosphatidylethanolamine flippase activity", "id": "GO:0090555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090555", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "phosphatidylserine flippase activity", "id": "GO:0140346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38567", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR09-1", "A0A8V0Y7I0-1", "A0A3Q2U2N5-1", "A0A8V0YUZ4-1", "A0A8V0YJI3-1", "A0A8V0YYJ1-1" ], "evidence": [ { "id": "38567", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38567" } ] }, { "id": "66132", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUZ4-1", "A0A8V0YJI3-1", "A0A8V0YYJ1-1" ], "evidence": [ { "id": "66132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66132" } ] }, { "id": "R-GGA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, tertiary granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "P15120-1", "Q5F352-1", "A0A8V0ZZE4-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6798747", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798747" } ] }, { "id": "R-GGA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "A0A3Q2U2N5-1", "A0A8V1AKE3-1", "P15120-1", "A0A1D5P3W4-1", "Q5F3C1-1", "A0A8V1AN75-1", "A0A8V0ZZE4-1", "F1NSA8-1", "A0A8V0YXK7-1", "A0A8V0Y5N7-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799350" } ] }, { "id": "R-GGA-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR09-1", "A0A8V1AG66-1", "A0A8V1AKE5-1", "A0A1D5P8E2-1", "A0A3Q2U2N5-1", "F1NUR8-1", "A0A8V0Y7I0-1", "E1BX05-1", "A0A8V0YU83-1", "A0A8V0YUZ4-1", "A0A8V0YYJ1-1", "A0A8V0YJI3-1", "A0A8V0YKR1-1" ], "evidence": [ { "id": "R-GGA-939763", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-939763" } ] }, { "id": "R-GGA-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR09-1", "A0A8V1AG66-1", "A0A8V1AKE5-1", "A0A1D5P8E2-1", "A0A3Q2U2N5-1", "F1NUR8-1", "A0A8V0Y7I0-1", "E1BX05-1", "A0A8V0YU83-1", "A0A8V0YUZ4-1", "A0A8V0YYJ1-1", "A0A8V0YJI3-1", "A0A8V0YKR1-1" ], "evidence": [ { "id": "R-GGA-947591", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-947591" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5P8E2", "gene_name": "ATP9B", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A1D5P8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E2" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A1D5P8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E2" } ] } ] }, { "uniprot_ac": "A0A3Q2U2N5", "gene_name": "ATP8A1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XR09", "gene_name": "ATP8A2", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0XR09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR09" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0XR09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR09" } ] } ] }, { "uniprot_ac": "A0A8V0Y5N7", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] } ] }, { "uniprot_ac": "A0A8V0Y7I0", "gene_name": "ATP8B1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0Y7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7I0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7I0" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YJI3", "gene_name": "ATP11A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] } ] }, { "uniprot_ac": "A0A8V0YKR1", "gene_name": "ATP10D", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ] } ] }, { "uniprot_ac": "A0A8V0YMC7", "gene_name": "PLD1", "activity": [ { "ec_number": "3.1.4.4", "activity": "a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ] }, { "ec_number": "3.1.4.4", "activity": "", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ] } ] }, { "uniprot_ac": "A0A8V0YU83", "gene_name": "ATP10A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU83" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU83" } ] } ] }, { "uniprot_ac": "A0A8V0YUZ4", "gene_name": "ATP11C", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YUZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ4" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YUZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ4" } ] } ] }, { "uniprot_ac": "A0A8V0YXK7", "gene_name": "HMOX2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0A8V0YXK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXK7" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "A0A8V0YXK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXK7" } ] } ] }, { "uniprot_ac": "A0A8V0YYJ1", "gene_name": "ATP11B", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YYJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYJ1" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YYJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYJ1" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V1AG66", "gene_name": "ATP8B2", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V1AG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG66" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V1AG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG66" } ] } ] }, { "uniprot_ac": "A0A8V1AKE3", "gene_name": "AGPAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0A8V1AKE3", "database": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJK8-1", "uniprot_ac": "A0A8V0YJK8", "uniprot_id": "A0A8V0YJK8_CHICK", "mass": { "chemical_mass": 52415.0, "monoisotopic_mass": 52415.0 }, "refseq": {}, "gene_names": [ { "name": "RNF14", "type": "recommended", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF14", "type": "recommended", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.31", "type": "synonym", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 14", "type": "synonym", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8", "locus": { "chromosome": "13", "start_pos": 16777238, "end_pos": 16770515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013286", "url": "https://www.ensembl.org/id/ENSGALG00010013286" } ] } } ], "crossref": [ { "id": "A0A8V0YJK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16628", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16628", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20354", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20354", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23820", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23820", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD80", "url": "https://www.orthodb.org/?gene=A0A8V0YD80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD85", "url": "https://www.orthodb.org/?gene=A0A8V0YD85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJK8", "url": "https://www.orthodb.org/?gene=A0A8V0YJK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11685", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11685", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEDREAQEDELLALASIYDEDEFKRAESAQGGETRICLELPQNFRVFVSGNSTEGPQSSGFECTVCFLPPLVLNFELPPDYPSTSPPAFTLSSKWLSPAQLSALCKHLDNLWEENRGCVVLFAWMQFLKEETLSYLNISSPYELKMCQQGNTQGGTPSVHQDAEDCGAAVGCAAAEEEIDERAVQDVESLSSLIREILDFDQAQRRKCFNSKMYLCNICFCEKLGTECMYFTECSHVYCKACLKDYFEIQIRDGQVHCLNCPEPKCSSVATPGQVKELVGEQLFARYDRLLLQSTLDLMADVVYCPRPGCQTPVMQEPGCTMGICSCCNYAFCTLCKMTYHGVSPCKITAEKLMDLRNEYLEADEATKRFLEQRYGKRVIQKALEEMESKEWLEKNSKACPCCSTPIEKLDGCNKMTCTGCMQYFCWLCMASLSRVNPYKHFNDPSSPCFDRLFQAMQIDVL", "length": 464, "header": "tr|A0A8V0YJK8-1|A0A8V0YJK8_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF14 OS=Gallus gallus OX=9031 GN=RNF14 PE=1 SV=1 CANONICAL=A0A8V0YJK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD80/entry", "sequence": { "sequence": "MSSEDREAQEDELLALASIYDEDEFKRAESAQGGETRICLELPQNFRVFVSGNSTEGPQSSGFECTVCFLPPLVLNFELPPDYPSTSPPAFTLSSKWLSPAQLSALCKHLDNLWEENRGCVVLFAWMQFLKEETLSYLNISSPYELKMCQQGNTQGGTPSVHQDAEDCGCRGLCCS", "length": 176, "header": "tr|A0A8V0YD80-1|A0A8V0YJK8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF14 OS=Gallus gallus OX=9031 GN=RNF14 PE=1 SV=1 CANONICAL=A0A8V0YJK8-1" }, "locus": { "chromosome": "13", "start_pos": 16772900, "end_pos": 16771545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031945.1", "url": "https://www.ensembl.org/id/ENSGALT00010031945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018738.1", "url": "https://www.ensembl.org/id/ENSGALP00010018738.1" } ] } }, { "isoform_ac": "A0A8V0YD85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD85/entry", "sequence": { "sequence": "MSSEDREAQEDELLALASIYDEDEFKRAESAQGGETRICLELPQNFRVFVSGNSTEGPQSSGFECTVCFLPPLVLNFELPPDYPSTSPPAFTLSSKWLSPAQLSALCKHLDNLWEENRGCVVLFAWMQFLKEETLSYLNISSPYELKMCQQGNTQGGTPSVHQDAEDCGAAVGCAAAEEEIDERAVQDVESLSSLIREILDFDQAQRRKCFNSKMYLCNICFCEKLGTECMYFTECSHVYCKACLKDYFEIQIRDGQVHCLNCPEPKCSSVATPGQVKELVGEQLFARYDRLLLQSTLDLMADVVYCPRPGCQTPVMQEPGCTMGICSCCNYAFCTLCKMTYHGVSPCKITAEKLMDLRNEYLEADEATKRFLEQRYGKRVIQKALEEMESKEWLEKNSKACPCCSTPIEVNCFKLCRLTVSSGKMKTSVLL", "length": 432, "header": "tr|A0A8V0YD85-1|A0A8V0YJK8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF14 OS=Gallus gallus OX=9031 GN=RNF14 PE=1 SV=1 CANONICAL=A0A8V0YJK8-1" }, "locus": { "chromosome": "13", "start_pos": 16776043, "end_pos": 16771545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031952.1", "url": "https://www.ensembl.org/id/ENSGALT00010031952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018744.1", "url": "https://www.ensembl.org/id/ENSGALP00010018744.1" } ] } }, { "isoform_ac": "A0A8V0YJK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8/entry", "sequence": { "sequence": "MSSEDREAQEDELLALASIYDEDEFKRAESAQGGETRICLELPQNFRVFVSGNSTEGPQSSGFECTVCFLPPLVLNFELPPDYPSTSPPAFTLSSKWLSPAQLSALCKHLDNLWEENRGCVVLFAWMQFLKEETLSYLNISSPYELKMCQQGNTQGGTPSVHQDAEDCGAAVGCAAAEEEIDERAVQDVESLSSLIREILDFDQAQRRKCFNSKMYLCNICFCEKLGTECMYFTECSHVYCKACLKDYFEIQIRDGQVHCLNCPEPKCSSVATPGQVKELVGEQLFARYDRLLLQSTLDLMADVVYCPRPGCQTPVMQEPGCTMGICSCCNYAFCTLCKMTYHGVSPCKITAEKLMDLRNEYLEADEATKRFLEQRYGKRVIQKALEEMESKEWLEKNSKACPCCSTPIEKLDGCNKMTCTGCMQYFCWLCMASLSRVNPYKHFNDPSSPCFDRLFQAMQIDVL", "length": 464, "header": "tr|A0A8V0YJK8-1|A0A8V0YJK8_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF14 OS=Gallus gallus OX=9031 GN=RNF14 PE=1 SV=1 CANONICAL=A0A8V0YJK8-1" }, "locus": { "chromosome": "13", "start_pos": 16776117, "end_pos": 16771545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031949.1", "url": "https://www.ensembl.org/id/ENSGALT00010031949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018741.1", "url": "https://www.ensembl.org/id/ENSGALP00010018741.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "regulation of androgen receptor signaling pathway", "id": "GO:0060765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "protein K6-linked ubiquitination", "id": "GO:0085020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "protein-RNA covalent cross-linking repair", "id": "GO:0160127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", 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"IPR007529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DESFCIR", "url": "https://omabrowser.org/oma/group/DESFCIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDB0", "url": "https://www.orthodb.org/?gene=A0A8V0YDB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEK3", "url": "https://www.orthodb.org/?gene=A0A8V0YEK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YGQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLG6", "url": "https://www.orthodb.org/?gene=A0A8V0YLG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH0", "url": "https://www.orthodb.org/?gene=A0A8V0YLH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04438", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04438", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDTMLKMGFQQQVLDILEDISHDHQTILVSATIPVGIEHLANQLLHNFVRITIGEKNLPCSNVRQIILWVEEPSKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 622, "header": "tr|A0A8V0YGQ1-1|A0A8V0YGQ1_CHICK Isoform 1 of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDB0/entry", "sequence": { "sequence": "MNLGGNGLEAVFRSMFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDEVDTMLKMGFQQQVLDILEDISHDHQTILVSATIPVGIEHLANQLLHNFVRITIGEKNLPCSNVRQIILWVEEPSKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 639, "header": "tr|A0A8V0YDB0-1|A0A8V0YGQ1_CHICK Computationally mapped isoform of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "locus": { "chromosome": "8", "start_pos": 1465389, "end_pos": 1452480, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029212.1", "url": "https://www.ensembl.org/id/ENSGALT00010029212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016941.1", "url": "https://www.ensembl.org/id/ENSGALP00010016941.1" } ] } }, { "isoform_ac": "A0A8V0YEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK3/entry", "sequence": { "sequence": "MTTLVDFRKLQTHIRLKRSMFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDEVDTMLKMGFQQQVLDILEDISHDHQTILVSATIPVGIEHLANQLLHNFVRITIGEKNLPCSNVRQIILWVEEPSKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 644, "header": "tr|A0A8V0YEK3-1|A0A8V0YGQ1_CHICK Computationally mapped isoform of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "locus": { "chromosome": "8", "start_pos": 1465389, "end_pos": 1445238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029216.1", "url": "https://www.ensembl.org/id/ENSGALT00010029216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016944.1", "url": "https://www.ensembl.org/id/ENSGALP00010016944.1" } ] } }, { "isoform_ac": "A0A8V0YGQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1/entry", "sequence": { "sequence": "MFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDTMLKMGFQQQVLDILEDISHDHQTILVSATIPVGIEHLANQLLHNFVRITIGEKNLPCSNVRQIILWVEEPSKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 622, "header": "tr|A0A8V0YGQ1-1|A0A8V0YGQ1_CHICK Isoform 1 of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "locus": { "chromosome": "8", "start_pos": 1465389, "end_pos": 1458128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029209.1", "url": "https://www.ensembl.org/id/ENSGALT00010029209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016940.1", "url": "https://www.ensembl.org/id/ENSGALP00010016940.1" } ] } }, { "isoform_ac": "A0A8V0YLG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG6/entry", "sequence": { "sequence": "MFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDEDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 541, "header": "tr|A0A8V0YLG6-1|A0A8V0YLG6_CHICK Computationally mapped isoform of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "locus": { "chromosome": "8", "start_pos": 1465389, "end_pos": 1458128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029205.1", "url": "https://www.ensembl.org/id/ENSGALT00010029205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016938.1", "url": "https://www.ensembl.org/id/ENSGALP00010016938.1" } ] } }, { "isoform_ac": "A0A8V0YLH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH0/entry", "sequence": { "sequence": "MDFIQLFLKGKYILVEISAYSTKVSVYIGLLQICLIPKRSMFLPRSVKVKRSADEDKSCTAKRNRLSSGGSSLEESTEFQDGKSAETATSTSKCNSNEVVQHTEPVAVPSDLGVPDASSGEDKGNTAEESSSEEPVKSFSKSQRWAEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQMQEKEEKLKSAHLAKGESQEESHLLNTAYFYKDHSFILSLQDEQVENLKLQLGIAIQGQQVPRPIIEFEHCGFPETLNSNLKNSGYEVPTPIQMQMIPVGLLGRDIVASADTGSGKTAAFLLPVIMKVLNETETPSALILAPTRELAIQIERQAKELMAGLPNMRTVLLVGGLPLPPQLHRLKQSVKVIIATPGRLLEILRQSSVQLHGIKIVVVDEVDTMLKMGFQQQVLDILEDISHDHQTILVSATIPVGIEHLANQLLHNFVRITIGEKNLPCSNVRQIILWVEEPSKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSDAVHKITGLQCTSMHSEKSQVERTAILQGLLQEKYEVIVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRAGRLGHSGTAITFINNNGKKLFWDVVKRVKPTGTILPPQLLNSPYLHDQKRREQQRLKQLENSLVTGDNIMDIIRKHDKNNSQR", "length": 665, "header": "tr|A0A8V0YLH0-1|A0A8V0YLH0_CHICK Computationally mapped isoform of RNA helicase OS=Gallus gallus OX=9031 GN=DDX59 PE=3 SV=1 CANONICAL=A0A8V0YGQ1-1" }, "locus": { "chromosome": "8", "start_pos": 1465389, "end_pos": 1451241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029214.1", "url": "https://www.ensembl.org/id/ENSGALT00010029214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016943.1", "url": "https://www.ensembl.org/id/ENSGALP00010016943.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NMG4-1", "protein_name": "Probable ATP-dependent RNA helicase DDX59", "gene_name": "DDX59", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFVPRSLKIKRNANDDSGNCVAKKVKAEAEDRGLDAGGDSLADASGTEGAAAAAHQGAQPHPLPGPTGPVSEGTLPDSEPGTQAGDLPEEPVKSFSKTQRQAEPGEPICVVCGRYGEYVCDETDEDVCSLECKAKHLLQVRGVEAASEPSRPQKAGSEPAAPGPAPYVYTEHAFVSHLREDQIENLRRQLGITVRGRGVPRPIVDFEHCGFPEALNRNLKASGYEVPTPIQMQMIPVGLLGRDVLASADTGSGKTAAFLLPVILRALSQSKSPSGLVLTPTRELAIQIERQAKELMSGLPCLRTALLVGGLPAPPQRHRLRQRIQVIIATPGRLLDIIKQRSVELGSIKIVVVDEADTMLKMGFQQQVLDVLEQLPHDCQTVLASATIPASVEQLACQLLRDPVAITAGERNLPCPSVRQIVLWVEEPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSTSVHSDKTQMERKNILKGLLEGDYDVVVSTGVLGRGLDLVGVKLVVNFDMPSSMDEYVHQIGRVGRLGQHGTAITFINNNSKRLFWDIAKRVKPTGSLLPPQLLNSPYLHDQKRKEQQKDRQTQDNLVTGANLMDIIRKHDRSNAQK", "length": 620 }, "evidence": [ { "id": "A0A8V0YGQ1", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3EBD3-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 41", "gene_name": "RH41", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNEEGCVPHNSDVVKQKSIDQRAPLSGEPKCVICSRYGEYICDETNDDVCSLECKQALLRRVDSARVFPATDECFYVRDPGSSSHDAQLLRRKLDIHVQGQGSAVPPPVLTFTSCGLPPKLLLNLETAGYDFPTPIQMQAIPAALTGKSLLASADTGSGKTASFLVPIISRCTTYHSEHPSDQRRNPLAMVLAPTRELCVQVEDQAKMLGKGLPFKTALVVGGDPMSGQLYRIQQGVELIIGTPGRVVDLLSKHTIELDNIMTFVLDEVDCMLQRGFRDQVMQIFQALSQPQVLLFSATISREVEKVGGSLAKEIILVSIGNPNKPNKAVNQLAIWVDAKQKKQKLFDILRSQNHFKPPAVVYVSSRVGADLLANAITVVTGVKALSIHGEKPMKERRDVMGSFLGGEVPVLVSTGVLGRGVDLLVVRQVIVFDMPSTIKEYIHVIGRASRMGEKGTAIVFVNEDDRNLFPDLVAALKSSGAAIPKELINLTSREMHNKKRRVGY", "length": 505 }, "evidence": [ { "id": "A0A8V0YGQ1", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5T1V6-1", "protein_name": "Probable ATP-dependent RNA helicase DDX59", "gene_name": "DDX59", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVPRSLKIKRNANDDGKSCVAKIIKPDPEDLQLDKSRDVPVDAVATEAATIDRHISESCPFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYICDKTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVTGANLMDIIRKHDKSNSQK", "length": 619 }, "evidence": [ { "id": "A0A8V0YGQ1", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66HG7-1", "protein_name": "Probable ATP-dependent RNA helicase DDX59", "gene_name": "Ddx59", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVPRSLKLKRNSNDDLKSCEAKKSKPEAAGLQLEGNRETLVLESVTKEAVTADRPGSASSTSSPSCQLAEVCSTGPDQGVKDSHPSEEPVKSFSKTQRWPEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQVKEEEGSLKPSSPQGAASEPESPLDAFYVYKEHPFIVALRDDQIETLKQQLGISVQGQEVARPIIDFEHCGFPETLNQNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIIRALPEDKTPSALILTPTRELAIQIERQAKELMRGLPRMKTVLLVGGLPLPPQLYRLQQHVKADTMLKMGFQQQVLDVLEHTPSDCQTVLVSATIPDSIDQLADQLLHNPVRIVTGDKNLPCSSVRQIILWVEDPAKKKKLFEILNDQKLFKPPVLVFVDCKLGADLLSEAVQKITGLSSTSIHSEKSQVERREILKGLLEGDYEVVVSTGILGRGLDLVNVKLVVNFDMPSSLDEYVHQVGRVGRLGQNGTAITFINNNSKRLFWDVAKRVKPTGSILPPQLLNSPYLHEQKRKEQQKDRQTQSSLVTGANLMDIIRKHEKSSSQK", "length": 589 }, "evidence": [ { "id": "A0A8V0YGQ1", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DBN9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX59", "gene_name": "Ddx59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFVPRSLKIKRSSNDDLKSGEAKKSKPEAGGLQVEGDRDTPVHTSVTEEAVTADKPGHASSTNSPSCQLAEVSSTGPDEGVKDSHPSEEPVKSFSKTQRWPEPGEPVCVVCGRYGEYICDKTDEDVCSLECKAKHLLQVKEGEGSLRPSSPQRVAAEPESPLDAFYVYKEHPFIVTLKEDQIETLKQQLGISVQGQDVARPIIDFEHCGFPETLNQNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIIRAFSEDKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLRQHVKVIIATPGRLLDIIKQSSVSLSGIKIVVVDEADTMLKMGFQQQVLDVLEHTPGDCQTILVSATIPDSIEQLTDQLLHNPVRIITGDKNLPCASVRQIILWVEDPAKKKKLFEILNDQKLFKPPVLVFVDCKLGADLLSEAVQKITGLNSTSIHSEKSQVERRDILKGLLEGDYEVVVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQVGRVGRLGQNGTAITFINNNSKRLFWDVAKRVKPTGSILPPQLLNSPYLHEQKRKEQQKDRQTQNSLVTGANLMDIIRKHEKSSSQK", "length": 619 }, "evidence": [ { "id": "A0A8V0YGQ1", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": 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"ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": 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"ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": 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] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 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"uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", 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"activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": 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5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] } ] }, { "uniprot_ac": "O93295", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] } ] }, { "uniprot_ac": "P08023", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08023" } ] } ] }, { "uniprot_ac": "P08110", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08110" } ] } ] }, { "uniprot_ac": "P37383", "gene_name": "RAD51A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P37383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37383" } ] } ] }, { "uniprot_ac": "P53478", 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"MAAPLRLGRAARLLPAAAARVAASEPLPRLSSSSSRHSAPPPAMQAFQYPEVYRDEAAVLDYHGHQISDPYCWLEDPDSEQTKAFVEAQNKLTVPFLEQCPVRGLFKERMTELYDYPKYSCHFKKGKSHFAIFCSFRYFHFYNTGLQNQRVLYVQDSLDADAKVFLDPNKLSDDGTVALRGYAFSEDGEYFAYGLSSSGSDWVTIKFMKVEGPEELPDTLERVKFSCMAWTHDGKGMFYNCYPKQDGKSDGTETSTNLHQKLHYHVLGTNQSEDILCAEFPDEPKWMGGAEISDDGRYVLLSIREGCDPVNRLWYCDLQKESQGISGILQWVKLIDNFEAEYEYVTNEGTVFTFKTNRHSPNYRLINIDFSDPEESKWKVLIPEHERDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGAHLKTFPLDVGSIVGYSGQKKDNEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGFDPSVYQTIQVFYPSKDGTKIPMFIIHKKGIKLDGSHPAFLYGYGGFNISITPSYSVSRLIFVRHLGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQYAAKYLIREGYTSPKKLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDHKEQFEWLCKYSPLHNVKLPEEDGIQYPATLLLTADHDDRVVPLHSLKFIATLQYVVGRSRKQTNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNLDWIE", "length": 762, "header": "tr|A0A8V0YJW4-1|A0A8V0YJW4_CHICK Isoform 1 of Prolyl endopeptidase OS=Gallus gallus OX=9031 GN=PREP PE=1 SV=1 CANONICAL=A0A8V0YJW4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDG8/entry", "sequence": { "sequence": "RTLLLTQNVCRDELVLDYHGHQISDPYCWLEDPDSEQTKAFVEAQNKLTVPFLEQCPVRGLFKERMTELYDYPKYSCHFKKGKRYFHFYNTGLQNQRVLYVQDSLDADAKVFLDPNKLSDDGTVALRGYAFSEDGEYFAYGLSSSGSDWVTIKFMKVEGPEELPDTLERVKFSCMAWTHDGKGMFYNCYPKQDGKSDGTETSTNLHQKLHYHVLGTNQSEDILCAEFPDEPKWMGGAEISDDGRYVLLSIREGCDPVNRLWYCDLQKESQGISGILQWVKLIDNFEAEYEYVTNEGTVFTFKTNRHSPNYRLINIDFSDPEESKWKVLIPEHERDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGAHLKTFPLDVGSIVGYSGQKKDNEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGFDPSVYQTIQVFYPSKDGTKIPMFIIHKKGIKLDGSHPAFLYGYGGFNISITPSYSVSRLIFVRHLGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQYAAKYLIREGYTSPKKLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDHKEQFEWLCKYSPLHNVKLPEEDGIQYPATLLLTADHDDRVVPLHSLKFIATLQYVVGRSRKQTNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNLDWIE", "length": 709, "header": "tr|A0A8V0YDG8-1|A0A8V0YJW4_CHICK Computationally mapped isoform of Prolyl endopeptidase OS=Gallus gallus OX=9031 GN=PREP PE=1 SV=1 CANONICAL=A0A8V0YJW4-1" }, "locus": { "chromosome": "3", "start_pos": 68500917, "end_pos": 68409323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032051.1", "url": "https://www.ensembl.org/id/ENSGALT00010032051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018841.1", "url": "https://www.ensembl.org/id/ENSGALP00010018841.1" } ] } }, { "isoform_ac": "A0A8V0YDH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH3/entry", "sequence": { "sequence": "MISKLCWRVLEKVRKGSVLRKREKMATSFMVLDYHGHQISDPYCWLEDPDSEQTKAFVEAQNKLTVPFLEQCPVRGLFKERMTELYDYPKYSCHFKKGKRYFHFYNTGLQNQRVLYVQDSLDADAKVFLDPNKLSDDGTVALRGYAFSEDGEYFAYGLSSSGSDWVTIKFMKVEGPEELPDTLERVKFSCMAWTHDGKGMFYNCYPKQDGKSDGTETSTNLHQKLHYHVLGTNQSEDILCAEFPDEPKWMGGAEISDDGRYVLLSIREGCDPVNRLWYCDLQKESQGISGILQWVKLIDNFEAEYEYVTNEGTVFTFKTNRHSPNYRLINIDFSDPEESKWKVLIPEHERDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGAHLKTFPLDVGSIVGYSGQKKDNEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGFDPSVYQTIQVFYPSKDGTKIPMFIIHKKGIKLDGSHPAFLYGYGGFNISITPSYSVSRLIFVRHLGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQYAAKYLIREGYTSPKKLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDHKEQFEWLCKYSPLHNVKLPEEDGIQYPATLLLTADHDDRVVPLHSLKFIATLQYVVGRSRKQTNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNLDWIE", "length": 725, "header": "tr|A0A8V0YDH3-1|A0A8V0YJW4_CHICK Computationally mapped isoform of Prolyl endopeptidase OS=Gallus gallus OX=9031 GN=PREP PE=1 SV=1 CANONICAL=A0A8V0YJW4-1" }, "locus": { "chromosome": "3", "start_pos": 68500917, "end_pos": 68405897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032056.1", "url": "https://www.ensembl.org/id/ENSGALT00010032056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018846.1", "url": "https://www.ensembl.org/id/ENSGALP00010018846.1" } ] } }, { "isoform_ac": "A0A8V0YJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW0/entry", "sequence": { "sequence": "MTMTTVRKGSVLRKREKMATSFMVLDYHGHQISDPYCWLEDPDSEQTKAFVEAQNKLTVPFLEQCPVRGLFKERMTELYDYPKYSCHFKKGKRYFHFYNTGLQNQRVLYVQDSLDADAKVFLDPNKLSDDGTVALRGYAFSEDGEYFAYGLSSSGSDWVTIKFMKVEGPEELPDTLERVKFSCMAWTHDGKGMFYNCYPKQDGKSDGTETSTNLHQKLHYHVLGTNQSEDILCAEFPDEPKWMGGAEISDDGRYVLLSIREGCDPVNRLWYCDLQKESQGISGILQWVKLIDNFEAEYEYVTNEGTVFTFKTNRHSPNYRLINIDFSDPEESKWKVLIPEHERDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGAHLKTFPLDVGSIVGYSGQKKDNEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGFDPSVYQTIQVFYPSKDGTKIPMFIIHKKGIKLDGSHPAFLYGYGGFNISITPSYSVSRLIFVRHLGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQYAAKYLIREGYTSPKKLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDHKEQFEWLCKYSPLHNVKLPEEDGIQYPATLLLTADHDDRVVPLHSLKFIATLQYVVGRSRKQTNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNLDWIE", "length": 718, "header": "tr|A0A8V0YJW0-1|A0A8V0YJW0_CHICK Computationally mapped isoform of Prolyl endopeptidase OS=Gallus gallus OX=9031 GN=PREP PE=1 SV=1 CANONICAL=A0A8V0YJW4-1" }, "locus": { "chromosome": "3", "start_pos": 68500917, "end_pos": 68405776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032063.1", "url": "https://www.ensembl.org/id/ENSGALT00010032063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018853.1", "url": "https://www.ensembl.org/id/ENSGALP00010018853.1" } ] } }, { "isoform_ac": "A0A8V0YJW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4/entry", "sequence": { "sequence": "MAAPLRLGRAARLLPAAAARVAASEPLPRLSSSSSRHSAPPPAMQAFQYPEVYRDEAAVLDYHGHQISDPYCWLEDPDSEQTKAFVEAQNKLTVPFLEQCPVRGLFKERMTELYDYPKYSCHFKKGKSHFAIFCSFRYFHFYNTGLQNQRVLYVQDSLDADAKVFLDPNKLSDDGTVALRGYAFSEDGEYFAYGLSSSGSDWVTIKFMKVEGPEELPDTLERVKFSCMAWTHDGKGMFYNCYPKQDGKSDGTETSTNLHQKLHYHVLGTNQSEDILCAEFPDEPKWMGGAEISDDGRYVLLSIREGCDPVNRLWYCDLQKESQGISGILQWVKLIDNFEAEYEYVTNEGTVFTFKTNRHSPNYRLINIDFSDPEESKWKVLIPEHERDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGAHLKTFPLDVGSIVGYSGQKKDNEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGFDPSVYQTIQVFYPSKDGTKIPMFIIHKKGIKLDGSHPAFLYGYGGFNISITPSYSVSRLIFVRHLGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQYAAKYLIREGYTSPKKLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDHKEQFEWLCKYSPLHNVKLPEEDGIQYPATLLLTADHDDRVVPLHSLKFIATLQYVVGRSRKQTNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNLDWIE", "length": 762, "header": "tr|A0A8V0YJW4-1|A0A8V0YJW4_CHICK Isoform 1 of Prolyl endopeptidase OS=Gallus gallus OX=9031 GN=PREP PE=1 SV=1 CANONICAL=A0A8V0YJW4-1" }, "locus": { "chromosome": "3", "start_pos": 68500917, "end_pos": 68408661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032068.1", "url": "https://www.ensembl.org/id/ENSGALT00010032068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018858.1", "url": "https://www.ensembl.org/id/ENSGALP00010018858.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "oligopeptidase activity", "id": "GO:0070012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" }, { "name": "angiotensin maturation", "id": "GO:0002003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 535, "end_pos": 757, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW4" }, { "id": "PF02897", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9A N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 474, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 270, "end_pos": 272 }, { "start_pos": 529, "end_pos": 531 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YK20-1", "uniprot_ac": "A0A8V0YK20", "uniprot_id": "A0A8V0YK20_CHICK", "mass": { "chemical_mass": 169945.0, "monoisotopic_mass": 169945.0 }, "refseq": {}, "gene_names": [ { "name": "ASXL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ] } ], "protein_names": [ { "name": "ASXL transcriptional regulator 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YK20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASXL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20", "locus": { "chromosome": "20", "start_pos": 10515725, "end_pos": 10501076, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013352", "url": "https://www.ensembl.org/id/ENSGALG00010013352" } ] } } ], "crossref": [ { "id": "428158", "url": "https://www.ncbi.nlm.nih.gov/gene/428158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428158", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428158", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGHFKRR", "url": "https://omabrowser.org/oma/group/DGHFKRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP1", "url": "https://www.orthodb.org/?gene=A0A8V0YDP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJC9", "url": "https://www.orthodb.org/?gene=A0A8V0YJC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK20", "url": "https://www.orthodb.org/?gene=A0A8V0YK20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13922", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13922", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YDP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFHLVDLTWLQCPLVSACPLGQCRAVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGDGLFYKLPGRISLFTLKKDALQWSRNLSVPEGDELEDTADAESCESNETSTVSGDNDGKCLITFILSCKYLLLCLTEGTSVSVSLDETSSNASCSTESQSKGPSTARESNRTASQTTKQKRKTGVMLPRVVLTPLKVNGAHMESASGFTGRHADGESSSTSSSSSSSLALCSATLRSRTEINRDPPQLLRGIRKPTAGQMKRNRGEDIDFETPGSILVNTNLRALINSRTFNALPSHFQQQLLYLLPEVDRQVGADGLMRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKRVEQWKEKFFEDYYGQKLGLTQEESQEQNLVQEDAENRTAVSVKGETRLPRGPSTRQRDGHFKKRSRADLRCRARRSLYKLRDSEQKEASKETASVGVDSSLHKDTKPEVDLKKDDLTSASATVLKPESSELHLSPETSKLHSKSEDLSLATANRIPCLSQESSAREPKDQKRKCFEEAASASFPEKKPRLEDRQSFRNTIESVHSEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPAYQICPRIIPNTEPSTRGRSGARTLADIKARALQARAQREAAAAAIGGGGGPGGGRNAEGSGGEPSSHRRRRRSKRTRRKRSSDLQRAQLLSSLRLNGEKASSEAAARAASTNSFASSKQDSFSSKREGSGVLECTAGAGSGGAQPGDGSPGGQCCDALTVSALDSTALERPEESPEQLFCDARTEASSCAVSQEAQSTEVTHVVPPAVGLSCPQAQGAEIGPAGGRVVSELRDVGIPTVQLDYSADVKENSTSRPALLPELPSGGKECHEPKVISRFRFNGSETTFVEQCVKNYSGDSKTVTAGAEEGVPALCNFTHLQAGRESDGKPSNEEQNAESLLKSSSCDDFISQNRIDTSEKLRERHPRTESEDGCQTLREAREFKANGDDEVQSTHSESTDTASDFEADVADENVEMEMCYRNLSCREVARKGSFCQSSTEECDKISSNSSLEAGNLPCVVDFPSVATVNTAPPPQRWGLHAPLPPKPERPSGSAQPVSSDASSPLVKQLLKGNRLLEEVLPVSHANIQVEGAQPPDMQSESLSVPMERGSSCYFGKESSPDVQIKTSALSRSDDFRPVRSSVDPQEKTCGSGAALPRAEDMENQPVPEKHSKIGLTLSCQDQLANVASASQKPEDTSPRERTFSSCSFEEQKESSKVHRVPQHNPLTNVITSQSPEKPNPTPEPPFLSPNVGSLGPNQMGNTSVNQNYVGVQGKKLFGSGFPCNPSVRLHHSRASDQVSVMGALAPSKQIPLTKSCASAEGMPAAREEWTSKQHGNSLGGIKNENVLACGSPAKSSGESQKDAAPNPAELREHSQSVPLVMDLPFLKLSREAGKRHNHPLEPSSIPSQFNIKQAFYGKLSKLQLNSTSFNYSSSAPAFPRSLAGSMMQLTHKANFAANHNTSLSVQMFADSSNVEEISFKCSCSLKAMIMCKGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1568, "header": "tr|A0A8V0YK20-1|A0A8V0YK20_CHICK Isoform 1 of ASXL transcriptional regulator 1 OS=Gallus gallus OX=9031 GN=ASXL1 PE=3 SV=1 CANONICAL=A0A8V0YK20-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP1/entry", "sequence": { "sequence": "MFHLVDLTWLQCPLVSACPLGQCRAVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGDGLFYKLPGRISLFTLKKDALQWSRNLSVPEGDELEDTADAESCESNETSTVSGDNDVSLDETSSNASCSTESQSKGPSTARESNRTASQTTKQKRKTGVMLPRVVLTPLKVNGAHMESASGFTGRHADGESSSTSSSSSSSLALCSATLRSRTEINRDPPQLLRGIRKPTAGQMKRNRGEDIDFETPGSILVNTNLRALINSRTFNALPSHFQQQLLYLLPEVDRQVGADGLMRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKRVEQWKEKFFEDYYGQKLGLTQEESQEQNLVQEDAENRTAVSVKGETRLPRGPSTRQRDGHFKKRSRADLRCRARRSLYKLRDSEQKEASKETASVGVDSSLHKDTKPEVDLKKDDLTSASATVLKPESSELHLSPETSKLHSKSEDLSLATANRIPCLSQESSAREPKDQKRKCFEEAASASFPEKKPRLEDRQSFRNTIESVHSEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPAYQICPRIIPNTEPSTRGRSGARTLADIKARALQARAQREAAAAAIGGGGGPGGGRNAEGSGGEPSSHRRRRRSKRTRRKRSSDLQRAQLLSSLRLNGEKASSEAAARAASTNSFASSKQDSFSSKREGSGVLECTAGAGSGGAQPGDGSPGGQCCDALTVSALDSTALERPEESPEQLFCDARTEASSCAVSQEAQSTEVTHVVPPAVGLSCPQAQGAEIGPAGGRVVSELRDVGIPTVQLDYSADVKENSTSRPALLPELPSGGKECHEPKVISRFRFNGSETTFVEQCVKNYSGDSKTVTAGAEEGVPALCNFTHLQAGRESDGKPSNEEQNAESLLKSSSCDDFISQNRIDTSEKLRERHPRTESEDGCQTLREAREFKANGDDEVQSTHSESTDTASDFEADVADENVEMEMCYRNLSCREVARKGSFCQSSTEECDKISSNSSLEAGNLPCVVDFPSVATVNTAPPPQRWGLHAPLPPKPERPSGSAQPVSSDASSPLVKQLLKGNRLLEEVLPVSHANIQVEGAQPPDMQSESLSVPMERGSSCYFGKESSPDVQIKTSALSRSDDFRPVRSSVDPQEKTCGSGAALPRAEDMENQPVPEKHSKIGLTLSCQDQLANVASASQKPEDTSPRERTFSSCSFEEQKESSKVHRVPQHNPLTNVITSQSPEKPNPTPEPPFLSPNVGSLGPNQMGNTSVNQNYVGVQGKKLFGSGFPCNPSVRLHHSRASDQVSVMGALAPSKQIPLTKSCASAEGMPAAREEWTSKQHGNSLGGIKNENVLACGSPAKSSGESQKDAAPNPAELREHSQSVPLVMDLPFLKLSREAGKRHNHPLEPSSIPSQFNIKQAFYGKLSKLQLNSTSFNYSSSAPAFPRSLAGSMMQLTHKANFAANHNTSLSVQMFADSSNVEEISFKCSCSLKAMIMCKGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1543, "header": "tr|A0A8V0YDP1-1|A0A8V0YK20_CHICK Computationally mapped isoform of ASXL transcriptional regulator 1 OS=Gallus gallus OX=9031 GN=ASXL1 PE=3 SV=1 CANONICAL=A0A8V0YK20-1" }, "locus": { "chromosome": "20", "start_pos": 10514638, "end_pos": 10502896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032140.1", "url": "https://www.ensembl.org/id/ENSGALT00010032140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018930.1", "url": "https://www.ensembl.org/id/ENSGALP00010018930.1" } ] } }, { "isoform_ac": "A0A8V0YJC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC9/entry", "sequence": { "sequence": "MREMKQRRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGDGLFYKLPGRISLFTLKKDALQWSRNLSVPEGDELEDTADAESCESNETSTVSGDNDGKCLITFILSCKYLLLCLTEGTSVSVSLDETSSNASCSTESQSKGPSTARESNRTASQTTKQKRKTGVMLPRVVLTPLKVNGAHMESASGFTGRHADGESSSTSSSSSSSLALCSATLRSRTEINRDPPQLLRGIRKPTAGQMKRNRGEDIDFETPGSILVNTNLRALINSRTFNALPSHFQQQLLYLLPEVDRQVGADGLMRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKRVEQWKEKFFEDYYGQKLGLTQEESQEQNLVQEDAENRTAVSVKGETRLPRGPSTRQRDGHFKKRSRADLRCRARRSLYKLRDSEQKEASKETASVGVDSSLHKDTKPEVDLKKDDLTSASATVLKPESSELHLSPETSKLHSKSEDLSLATANRIPCLSQESSAREPKDQKRKCFEEAASASFPEKKPRLEDRQSFRNTIESVHSEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPAYQICPRIIPNTEPSTRGRSGARTLADIKARALQARAQREAAAAAIGGGGGPGGGRNAEGSGGEPSSHRRRRRSKRTRRKRSSDLQRAQLLSSLRLNGEKASSEAAARAASTNSFASSKQDSFSSKREGSGVLECTAGAGSGGAQPGDGSPGGQCCDALTVSALDSTALERPEESPEQLFCDARTEASSCAVSQEAQSTEVTHVVPPAVGLSCPQAQGAEIGPAGGRVVSELRDVGIPTVQLDYSADVKENSTSRPALLPELPSGGKECHEPKVISRFRFNGSETTFVEQCVKNYSGDSKTVTAGAEEGVPALCNFTHLQAGRESDGKPSNEEQNAESLLKSSSCDDFISQNRIDTSEKLRERHPRTESEDGCQTLREAREFKANGDDEVQSTHSESTDTASDFEADVADENVEMEMCYRNLSCREVARKGSFCQSSTEECDKISSNSSLEAGNLPCVVDFPSVATVNTAPPPQRWGLHAPLPPKPERPSGSAQPVSSDASSPLVKQLLKGNRLLEEVLPVSHANIQVEGAQPPDMQSESLSVPMERGSSCYFGKESSPDVQIKTSALSRSDDFRPVRSSVDPQEKTCGSGAALPRAEDMENQPVPEKHSKIGLTLSCQDQLANVASASQKPEDTSPRERTFSSCSFEEQKESSKVHRVPQHNPLTNVITSQSPEKPNPTPEPPFLSPNVGSLGPNQMGNTSVNQNYVGVQGKKLFGSGFPCNPSVRLHHSRASDQVSVMGALAPSKQIPLTKSCASAEGMPAAREEWTSKQHGNSLGGIKNENVLACGSPAKSSGESQKDAAPNPAELREHSQSVPLVMDLPFLKLSREAGKRHNHPLEPSSIPSQFNIKQAFYGKLSKLQLNSTSFNYSSSAPAFPRSLAGSMMQLTHKANFAANHNTSLSVQMFADSSNVEEISFKCSCSLKAMIMCKGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1563, "header": "tr|A0A8V0YJC9-1|A0A8V0YK20_CHICK Computationally mapped isoform of ASXL transcriptional regulator 1 OS=Gallus gallus OX=9031 GN=ASXL1 PE=3 SV=1 CANONICAL=A0A8V0YK20-1" }, "locus": { "chromosome": "20", "start_pos": 10514638, "end_pos": 10501151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032133.1", "url": "https://www.ensembl.org/id/ENSGALT00010032133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018923.1", "url": "https://www.ensembl.org/id/ENSGALP00010018923.1" } ] } }, { "isoform_ac": "A0A8V0YK20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20/entry", "sequence": { "sequence": "MFHLVDLTWLQCPLVSACPLGQCRAVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGDGLFYKLPGRISLFTLKKDALQWSRNLSVPEGDELEDTADAESCESNETSTVSGDNDGKCLITFILSCKYLLLCLTEGTSVSVSLDETSSNASCSTESQSKGPSTARESNRTASQTTKQKRKTGVMLPRVVLTPLKVNGAHMESASGFTGRHADGESSSTSSSSSSSLALCSATLRSRTEINRDPPQLLRGIRKPTAGQMKRNRGEDIDFETPGSILVNTNLRALINSRTFNALPSHFQQQLLYLLPEVDRQVGADGLMRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKRVEQWKEKFFEDYYGQKLGLTQEESQEQNLVQEDAENRTAVSVKGETRLPRGPSTRQRDGHFKKRSRADLRCRARRSLYKLRDSEQKEASKETASVGVDSSLHKDTKPEVDLKKDDLTSASATVLKPESSELHLSPETSKLHSKSEDLSLATANRIPCLSQESSAREPKDQKRKCFEEAASASFPEKKPRLEDRQSFRNTIESVHSEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPAYQICPRIIPNTEPSTRGRSGARTLADIKARALQARAQREAAAAAIGGGGGPGGGRNAEGSGGEPSSHRRRRRSKRTRRKRSSDLQRAQLLSSLRLNGEKASSEAAARAASTNSFASSKQDSFSSKREGSGVLECTAGAGSGGAQPGDGSPGGQCCDALTVSALDSTALERPEESPEQLFCDARTEASSCAVSQEAQSTEVTHVVPPAVGLSCPQAQGAEIGPAGGRVVSELRDVGIPTVQLDYSADVKENSTSRPALLPELPSGGKECHEPKVISRFRFNGSETTFVEQCVKNYSGDSKTVTAGAEEGVPALCNFTHLQAGRESDGKPSNEEQNAESLLKSSSCDDFISQNRIDTSEKLRERHPRTESEDGCQTLREAREFKANGDDEVQSTHSESTDTASDFEADVADENVEMEMCYRNLSCREVARKGSFCQSSTEECDKISSNSSLEAGNLPCVVDFPSVATVNTAPPPQRWGLHAPLPPKPERPSGSAQPVSSDASSPLVKQLLKGNRLLEEVLPVSHANIQVEGAQPPDMQSESLSVPMERGSSCYFGKESSPDVQIKTSALSRSDDFRPVRSSVDPQEKTCGSGAALPRAEDMENQPVPEKHSKIGLTLSCQDQLANVASASQKPEDTSPRERTFSSCSFEEQKESSKVHRVPQHNPLTNVITSQSPEKPNPTPEPPFLSPNVGSLGPNQMGNTSVNQNYVGVQGKKLFGSGFPCNPSVRLHHSRASDQVSVMGALAPSKQIPLTKSCASAEGMPAAREEWTSKQHGNSLGGIKNENVLACGSPAKSSGESQKDAAPNPAELREHSQSVPLVMDLPFLKLSREAGKRHNHPLEPSSIPSQFNIKQAFYGKLSKLQLNSTSFNYSSSAPAFPRSLAGSMMQLTHKANFAANHNTSLSVQMFADSSNVEEISFKCSCSLKAMIMCKGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1568, "header": "tr|A0A8V0YK20-1|A0A8V0YK20_CHICK Isoform 1 of ASXL transcriptional regulator 1 OS=Gallus gallus OX=9031 GN=ASXL1 PE=3 SV=1 CANONICAL=A0A8V0YK20-1" }, "locus": { "chromosome": "20", "start_pos": 10514638, "end_pos": 10502896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032136.1", "url": "https://www.ensembl.org/id/ENSGALT00010032136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018926.1", "url": "https://www.ensembl.org/id/ENSGALP00010018926.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1293, "start_aa": "Thr", "end_pos": 1293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1293", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428158", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GKY0-1", "protein_name": "ASXL transcriptional regulator 1", "gene_name": "Asxl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMSREREENVHSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDAVQWSRNVATLDGEEPEDSADVESCGSNEASTVSGENDVSLDETSSNASCATEPQGRSLSNPRDGHRASSQANKQKKRTGVMLPRVVLTPLKVNGAHVEPASGFSGRHADGESGSPSSSSSGSLALGNSTIRSQAEVTRDPAPLLRGFRKPATGQMKRNRGEEVDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLAEGEFTHEMQVRLRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQKEDQEEAKIKSGFCVSGESVRPQRGPNTRQRDGHFKKRSRPDLRTRSRRNLYKKQEPEQAGIAKDANAAPDVSLSKDAKTDSPGVNSPPGPDVSSPASGQEGPKCPSEPVASQIQTEMDNLACASTSPDRTPTLPQDSVDQETKDQKRKSFEQEASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVAKGRPTYQICPRIVPITESSCRGWTGARTLADIKARALQARGARGYHCNREAAATAIGGGGGPGGGGSGAIDEGGGRDGSSGDGSEACGHSEPRGASSNPGESASDLQRTQLLPSCPLNGEHTQADAAMVRAKGEDSASLRKEENGLLTRAPGVLTSGLEDASQPPVAPTGDQPCQALPPLSSQTPVAEMLAEQAKLLPDDRTECEPRTPSWEKGGEDQGPTVPSEGSSGQSPLGDILGGGNDQIFDNMKEPVNMTPAFISELSLANSLQDRPSDDELGVGATGPHIRESRQETLKTEAFVSGSPGSWVPILSNYEVIKESYPEARENAPCLEPQDGKGWERTVPLVAAMPGGHAEVLPYHESCASHWTAPPPGVLGSTCSDSQQVDLERLEMNGISDILSPHNESTDTASDSEGHFSEDSSEVDACEITVVKGLLGGSEKQDWDPSASLSKASTDLSVLTRTEGVATPQSWVSRVCAVPHKIPDSLLLSSTECQPRSVCPPKPGSSAEVTNPLVMHLLHGNLPLEKVLAPGHRSNQPESPHLPLREQNQDRGTLQGTGGDNHLVARSNPGSVQTLKESILAQSYGASAGLVRAKASKAPGMSQKIARLVPSSDSQHPVTELTPSSSNLEEIDSKEHLSSFLCEEQKEAHSLSQGSDPGAAPGQFLGDHTTSKVPCFSSTNVSLSFGSEQTDGTLSDQNDVGGREKKLFGPRNTVATLQYPRSEEQIPLPAEVPPVFPSRKIEPSKNSVPDGVQTARENRTPKPPAVSAGSIKTEQTFLRDPIKADAENRKAAGYSSLELVGHLQGMPFVVDLPFWKLPREPGKGFSQPLEPPSIPSQLSIKQALYGKFSKLQLSPSSFNYSSSSAAFPRGLAGGVVQLSHKASFGTGHTASLSLQMFTDSSAVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1535 }, "evidence": [ { "id": "A0A8V0YK20", "url": "https://omabrowser.org/oma/group/A0A8V0YK20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59598-1", "protein_name": "Polycomb group protein ASXL1", "gene_name": "Asxl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDKQKRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDAVQWSRNAATVDGDEPEDSADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSHRASSQANKQKKRTGVMLPRVVLTPLKVNGAHVEPASGFSGRHADGESGSPSSSSSGSLALGNSAIRGQAEVTRDPAPLLRGFRKPATGQMKRNRGEEVDFETPGSILVNTNLRALINSRTFHALPLHFQQQLLLLLPEVDRQVGTDGLLRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRLRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQKEVQEEAKVKSGLCVSGESVRPQRGPNTRQRDGHFKKRSRPDLRTRSRRNIYKKQEPEQAGVAKDASAAPDVSLSKDTKTDLAGVNSTPGPDVSSATSGQEGPKCPSEPVASQIQAERDNLACASASPDRIPTLPQDTVDQETKDQKRKSFEQEASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVAKGRPTYQICPRIVPITESSCRGWTGARTLADIKARALQARGARGYHCNRETATTAIGGGGGPGGGGSGAIDEGGGRDSSSGDGSEACGHPEPRGAPSTSGESASDLQRTQLLPPCPLNGEHTPAEAAMPRARREDSASLRKEESCLLKRVPGVLTSGLEDASQPPIAPTGDQPCQALPPLSSQTPVAEMLTEQPKLLLDDRTECESSREDQGPTIPSESSSGRFPLGDLLGGGSDQAFDNMKEPVSMTPTFISELSLANYLQDRPDDDGLGLGATGLLIRESSRQEALTEAFASGSPTSWVPILSNYEVIKTSDPESRENIPCPEPQDEKEWERAVPLIAATESVPQPESCISHWTPPPAAVGSTGSDSEQVDLERLEMNGISEAPSPHSESTDTASDSEGHLSEDSSEVDASEVTVVKGSLGGDEKQDWDPSASLSKVNNDLSVLTRTGGVAASQSWVSRVCSVPHKIPDSLLLSSTECQPRSVCPLRPGSSVEVTNPLVMHLLHGNLPLEKVLPPGHRSSRLESSQLPLREQSQDRGTLQGTGENNRLAARINPGSAQTLKESILAQSYGASAGLVRAMASKAPAMSQKIAKMVTSLDSQHPETELTPSSGNLEEIDSKEHLSSFLCEEQKEGHSLSQGSDPGAAPGQCLGDHTTSKVPCFSSTNVSLSFGSEQTDGTLSDQNNAGGHEKKLFGPGNTVTTLQCPRSEEQTPLPAEVPPVFPSRKIEPSKNSVSGGVQTTRENRMPKPPPVSADSIKTEQTFLRDPIKADAENRKAAGYSSLELVGHLQGMPFVVDLPFWKLPREPGKGFSQPLEPSSIPSQLNIKQALYGKLSKLQLSPTSFNYSSSSATFPKGLAGGVVQLSHKASFGTGHTASLSLQMFADSSAVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1514 }, "evidence": [ { "id": "A0A8V0YK20", "url": "https://omabrowser.org/oma/group/A0A8V0YK20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXJ9-1", "protein_name": "Polycomb group protein ASXL1", "gene_name": "ASXL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLWTVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTREAAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSLLLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTKDQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAPQKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPGKSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPADPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKANAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1541 }, "evidence": [ { "id": "A0A8V0YK20", "url": "https://omabrowser.org/oma/group/A0A8V0YK20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "nuclear retinoic acid receptor binding", "id": "GO:0042974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "peroxisome proliferator activated receptor binding", "id": "GO:0042975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "PR-DUB complex", "id": "GO:0035517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035517", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "negative regulation of fat cell differentiation", "id": "GO:0045599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "negative regulation of peroxisome proliferator activated receptor signaling pathway", "id": "GO:0035359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "positive regulation of retinoic acid receptor signaling pathway", "id": "GO:0048386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "podocyte development", "id": "GO:0072015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" }, { "name": "regulation of kidney size", "id": "GO:0035564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1313, "end_pos": 1315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1477, "end_pos": 1479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1482, "end_pos": 1484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1512, "end_pos": 1514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJG5-1", "uniprot_ac": "A0A8V0YJG5", "uniprot_id": "A0A8V0YJG5_CHICK", "mass": { "chemical_mass": 87432.0, "monoisotopic_mass": 87432.0 }, "refseq": { "ac": "XP_040532384", "name": "protein FAM171B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040532384" }, "gene_names": [ { "name": "FAM171B", "type": "recommended", "evidence": [ { "id": "A0A8V0YJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" } ] }, { "name": "FAM171B", "type": "synonym", "evidence": [ { "id": "XP_040532384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040532384" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 171 member B", "type": "synonym", "evidence": [ { "id": "A0A8V0YJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5/entry#names_and_taxonomy" } ] }, { "name": "protein FAM171B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040532384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040532384" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052579.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040532384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040532384" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM171B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5", "locus": { "chromosome": "7", "start_pos": 1367440, "end_pos": 1399470, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013355", "url": "https://www.ensembl.org/id/ENSGALG00010013355" } ] } } ], "crossref": [ { "id": "A0A8V0YJG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "423991", "url": "https://www.ncbi.nlm.nih.gov/gene/423991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423991", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIAAPHP", "url": "https://omabrowser.org/oma/group/WIAAPHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP6", "url": "https://www.orthodb.org/?gene=A0A8V0YDP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJF3", "url": "https://www.orthodb.org/?gene=A0A8V0YJF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJG5", "url": "https://www.orthodb.org/?gene=A0A8V0YJG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK24", "url": "https://www.orthodb.org/?gene=A0A8V0YK24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRY3", "url": "https://www.orthodb.org/?gene=A0A8V0YRY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040532384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040532384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGTRGPPPSLLLALLLLLLQGRPTAAAATRPQPERAALPGGAPAAAASGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 792, "header": "tr|A0A8V0YJG5-1|A0A8V0YJG5_CHICK Isoform 1 of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP6/entry", "sequence": { "sequence": "MAALFVHSVSALSWAALRCVEAVYCCGDLMAALWLYCGGCCSFIGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 787, "header": "tr|A0A8V0YDP6-1|A0A8V0YJG5_CHICK Computationally mapped isoform of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "locus": { "chromosome": "7", "start_pos": 1389140, "end_pos": 1368855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032145.1", "url": "https://www.ensembl.org/id/ENSGALT00010032145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018935.1", "url": "https://www.ensembl.org/id/ENSGALP00010018935.1" } ] } }, { "isoform_ac": "A0A8V0YJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF3/entry", "sequence": { "sequence": "MVAVAGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 748, "header": "tr|A0A8V0YJF3-1|A0A8V0YJG5_CHICK Computationally mapped isoform of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "locus": { "chromosome": "7", "start_pos": 1395913, "end_pos": 1368855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032152.1", "url": "https://www.ensembl.org/id/ENSGALT00010032152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018945.1", "url": "https://www.ensembl.org/id/ENSGALP00010018945.1" } ] } }, { "isoform_ac": "A0A8V0YJG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5/entry", "sequence": { "sequence": "MPGTRGPPPSLLLALLLLLLQGRPTAAAATRPQPERAALPGGAPAAAASGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 792, "header": "tr|A0A8V0YJG5-1|A0A8V0YJG5_CHICK Isoform 1 of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "locus": { "chromosome": "7", "start_pos": 1399377, "end_pos": 1368855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032165.1", "url": "https://www.ensembl.org/id/ENSGALT00010032165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018955.1", "url": "https://www.ensembl.org/id/ENSGALP00010018955.1" } ] } }, { "isoform_ac": "A0A8V0YK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK24/entry", "sequence": { "sequence": "MQLFQKVSSGLHVELGNQAGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 762, "header": "tr|A0A8V0YK24-1|A0A8V0YJG5_CHICK Computationally mapped isoform of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "locus": { "chromosome": "7", "start_pos": 1384821, "end_pos": 1368855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032142.1", "url": "https://www.ensembl.org/id/ENSGALT00010032142.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018932.1", "url": "https://www.ensembl.org/id/ENSGALP00010018932.1" } ] } }, { "isoform_ac": "A0A8V0YRY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRY3/entry", "sequence": { "sequence": "MRGAERDPSLIARLPRGARGGSVFMLKVQVNDIISHQYLAQAVVEVFVNYTKTNSTLTGNNGAVLIKVPYKLGLSLTIVSYKDGYMLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLSDAKSQPSVQFQKSLIKLPTDHHITNVTAYLTVPEQFLKVDSFLYTTGILLNKSGFKSIELTPLAAICANILLAGQELKVNGPIQITLPLPMSTVKSGDAIPAWTFDMKTGAWVSRGLGMVKEANDQLIWTYTAQHLGYWIAAPLPGTRESIISAVSKDITAYHTVFLTAILGGTVIIIIGFFAVLLCYCRDKCGRTQKKEKNTTKLDVIKKDQTTSTTHINHINAVKGSLKLEDKSQLYTPKMSSYSPQRRMSTDTEDGKSRDNFKIYSEDASYQSSYQTGQSINSPHSLEPSAGLRHLQPPKHTNGATSQAPRDIQEQNRYLTLQEEIYGLSHIPEHLMHIYNQPIAILQTSDLFHSPEQLHTAKSATLPRKGQLVYSPMMEPVNRDGYIQTLPKMPLHSHPQPSVCRDEKSTLDGEQGLPSQTSNWGRYTNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPIAQVRHSFIDIKKGRKTESNDTSLDSGVDMNEHHPGRKLEREKTFIKNMPHSKILYLEDLDLSSSESGTTVCTPEDQAVRHILDGGNGPAIEQHDEEGLRRKTVSGSQESGIPSPKKRDRPSLTKRDSKTNIWKKREERPLIPIN", "length": 763, "header": "tr|A0A8V0YRY3-1|A0A8V0YJG5_CHICK Computationally mapped isoform of Family with sequence similarity 171 member B OS=Gallus gallus OX=9031 GN=FAM171B PE=3 SV=1 CANONICAL=A0A8V0YJG5-1" }, "locus": { "chromosome": "7", "start_pos": 1399035, "end_pos": 1368855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032162.1", "url": "https://www.ensembl.org/id/ENSGALT00010032162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018952.1", "url": "https://www.ensembl.org/id/ENSGALP00010018952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423991", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MIA3-1", "protein_name": "Family with sequence similarity 171 member B", "gene_name": "FAM171B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARLSRRVPCTLLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQRQREEAEEERPEVPGASSTAAAPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTRNNGAVLISVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQNQANIWLFEDTILITGKLADAKSQPSVQFSKALIKLPNNHHISNVTGYLTVLQQFLKVDNFLYTTGITLNKSGFESIELTPLAAICVKIYSGGKELKVDGSIQISLPLLHTNDVSAGDHVPAWTFDMNTGAWVNHGQGMVKEYNSHLIWTYDAPHLGYWIAAPLPGTRGSGMNGDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNTTKLEVLKRDQTTSTTHINHISSVKVALKTEDKSQLFNAKSSSYSPQKKESSKVEAEERVSMVKTRDNLKIYNEDVSFLSVNQNNYSRNPAQSLEPNVGSKQLKHVNNNMSSSLGDTQEEKRYLTGNEEAYGHPHVPEQIMHIYSQPIAILQTSDLFPTPEQLHPAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHAQPPDAREENFPLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRAQSNDTSLDSGVDMNEHHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGAIMEHPGEESPGRKSTAEDFEANISPTKKRGRPPPLAKRDSKTNIWKKREERPLIPIN", "length": 820 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZTG3-1", "protein_name": "Family with sequence similarity 171, member B", "gene_name": "Fam171b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLCRRVSCALLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQEQRQREEAEEERMEVAGASFTLVVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTRSNGAVLIKVPYRLGLSLTIIAYKDGYVLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLTDAKSQPSVQFSKASIKLPDNHHISNVTGYLTVLQQFLKGDNFLSAIGITYSTGFENVELTPHAAICVKIYSGGKELNVAGPIHISLPLLHTSNVNVGDRIPAWTFNMKIGAWVHHDWGTVKEHNGHLIWTYDAPHLGYWIAAPSPSTLDLGINEDFPNVIGYHTAFLTAILGGTIVIIIVCLAALLCYCREKYGTPQKRERNITKLEILKRDQTTSTTHINHISSVKVALKAEDKPQLFNAKTSSYSPQKKETTKTETEERIPMVKTRDNFKIYNEDVSFLSVNHNNYSRNPTQSLEPSIGSKQPKHMNNNLSPSLGDAQEEKRYLTGNDEVYGRSHLPEQLMHIYSQPIAILQTSDLFSMPDQLHAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHTQDPDAREEDIVLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQLSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGGGVIIEHPREESPGSKSTVEDFEANVSPTKKRGRPLPLAKRDSKTNIWKKREERPLIPIN", "length": 823 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3IRX1-1", "protein_name": "Protein FAM171B precursor", "gene_name": "fam171b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLSGCLLLAALLIFSKDVSVRRAEGAALTRGLASLSDQDNAEDTRTSPVQGQGDATVSPPSSESLLTLKVWVKDASSQRFLTGALVSVFLNGSQIHSSRTLGNGEVTIIVPYRLGLTLTLVASMEGYMLTQLPWKTTKIPIFSVITLSVHPQTQGNIWLFEDTVLIARKTSDLSFQPSVQFPKSLLKLPENTTISMLSAYLTAPGLPTEKDSNYFTLNLNGKGGYRNIKLSPLAMISAQIVSNGKEVDVKGPIQLTIPLPYYTHLRPSDSLPAWTFNMTIGTWVNKGLGIVQMEKNGLVWTYTAPQLGNWIAAPLPSSGYMGLASSMDFIYYHTYLLVGILGGTLVVVVGFLSVIVFHCRDLNHEAGRRRWNSTRLTVLKKDQTTSTSSDEAQELFFHNGERSYSLAARGISHDASDSPRHQANYNIYVENVGRPGGNLYENIGAVGLEGLRAPMSNLYVNSDEVAKLREKMEQNGARHGGVENVVFKDKLFHIYNQPLAIVQAPELFNSQGQADPSGSRSATFPRNGMEHGAQTERNLKDSFTQTLPKAPQQDNDEQQSLEGAQAVAINPGLWGRYSHLLESVSVPGTLNEAAGMGPFRGELQGISEQTLLELTKGKPSIHPPRAWFVSLDGKPAAQVRHSVIELQGRHRPGSSNDTSLDSGVDMNELQQPLRKSEEPSSASMAKISGNQEQDLSSSEIGSPEDSSLRNTLESSSAAIPNLPEDRDAGDTSSESKSTPPPRRLRKVRDKKPDKKTSRHMREERPQTKH", "length": 771 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LET1-1", "protein_name": "Family with sequence similarity 171 member B", "gene_name": "FAM171B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARLSRRVPCTLLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQRQREEAEEEKPEVPEASSIATVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTRNNGAVLIRVPYKLGLSLTIIAYKDGYVLTHLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLYTTGITLNKSGFESIELTPLAAICVKIYSGGRELKVDGSIQVSLPLLHTNDISAGDHIPAWTFDMNTGAWVNHGRGMVKEYNNHLIWTYDAPHLGYWIAAPLLGTRGSGINGDSKDITAYHTVFLTAILGGTVVIVIGFFAVLLCYCRDKCGTTQKRERNITKLEVLKRDQTTSTTHINHISSVKVALKTEDKSQLFNAKNSSYSPQKKEPSKVEVEERVSMVKTRDNLKIYNEDVSFLSVNQNNYSRNTTQSLEPNVGSKQPKHINNNLSPSLGNAQEEKRYLTGSEEVYGHSHLPEQLVHIYSQPIAILQTSDLFSTPEQLHSAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHAQPPDAREESIPLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRAQSNDTSLDSGVDMNEHHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGAIMEHPGEESPGRKNTVDDFEANISPTKKRGRPPLAKKDSKTNIWRKREERPLLPIN", "length": 821 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14CH0-1", "protein_name": "Protein FAM171B", "gene_name": "Fam171b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLCRRVPCALLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQLQEQKQREEAEEGRPEVPGASSTLVAPVSVFMLKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKAFIKLPDNHHISNVTGYLTVLHQFLKVDSFLPATGVTYKSGLENVELTPHAAICVKIYSGGKELKVDGSIHVSLPLLHTSNIKIGDRIPAWTFDMNAGVWVHHGWGTVKEHNSHLIWTYDAPHLGYWIAAPSPATLDFGINDDFQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNITKLEILKRDQTTSTTHINHISSVKTALKAEDKPQLFNAKTSSYSPQRKETTKTEAEERISMVKTRDNFKIYNEDVSFLSVNHNYSRNPTQSLEPSMGSKQPKHINNNLSPSLGDAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFSMPEQLHAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHVQAPDAREEDIVLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILEGGSGVIIEHPGEESPGRKSTVEDFEANTSPTKKRGRPPPLAKRDSKTNIWKKREERPLIPLN", "length": 825 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P995-1", "protein_name": "Protein FAM171B", "gene_name": "FAM171B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLCRRVPCTLLLGLAVVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQQQQKQLEEAEEERTEVPGATSTLTVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRRGRPPLAKRDSKTNIWKKREERPLIPIN", "length": 826 }, "evidence": [ { "id": "A0A8V0YJG5", "url": "https://omabrowser.org/oma/group/A0A8V0YJG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" }, { "id": "PF20771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM171 C-terminal", "eco_id": "ECO_0000259", "start_pos": 577, "end_pos": 789, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG5" }, { "id": "PF10577", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10577" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM171 N-terminal", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 300, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YH22-1", "uniprot_ac": "A0A8V0YH22", "uniprot_id": "A0A8V0YH22_CHICK", "mass": { "chemical_mass": 120114.0, "monoisotopic_mass": 120114.0 }, "refseq": {}, "gene_names": [ { "name": "B4GALNT3", "type": "recommended", "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ] } ], "protein_names": [ { "name": "Beta-1,4-N-acetylgalactosaminyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.244", "type": "synonym", "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR5#function" }, { "database": "UniProtKB", "id": "RU364016", "url": "https://www.uniprot.org/uniprotkb/RU364016#function" }, { "database": "UniProtKB", "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22#function" }, { "database": "UniProtKB", "id": "A0A8V0YLU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "B4GALNT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22", "locus": { "chromosome": "1", "start_pos": 60414354, "end_pos": 60356304, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012274", "url": "https://www.ensembl.org/id/ENSGALG00010012274" } ] } } ], "crossref": [ { "id": "A0A8V0YH22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00761", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00761", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDR5", "url": "https://www.orthodb.org/?gene=A0A8V0YDR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH22", "url": "https://www.orthodb.org/?gene=A0A8V0YH22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLU8", "url": "https://www.orthodb.org/?gene=A0A8V0YLU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07691", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07691", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20493", "url": "https://www.rhea-db.org/rhea/20493", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERCSRDGNLIPKCMRWSKANIPDSQNKTQSKHSQGYESWRELAKVLADPNVPGGDLSLPFYYSQKVGHQNQEHQRSGRNKSNYAAMNNPVPWMPEFQGQANLHVFEDWCGSSTEQLRRNLHFPLYPHTRTVLKKLAVSPKWTNYGLRIFGYLHPFTDGEFQFAIAADDNAEFWLSSDEKTSGLQLLASVGKTGKEWTAPGEFGKFWSQQSKVVRLSAAGRYYFEVLHKQDDKGTDHVEVAWKLNDPDAKFKVIDSQYLSLFANETLLKMDEVGHIPQTLASHKRRATDSTGSKAHPADMLKPDPRDTLYKVPLLSKSRLRRALPDCPYKPSYLVNGFPLQRYQGLQFIHLSFVYPNDYSRLSHMEKENKCFYQENPYYLERFGFYKYIKMDRRKQSLDSEEKTEQPGFQEGNLDDLQYGEQDVESTVSPAHPNMQRAEPADTAPGTVVGSHRVYEDYSLREHRRLLSVGDIGEVTQRRRTKKSGVKTALLAPANQSLSRAGPERNPATKRPHLKAGVKDNSRSPPQHARAAQGRAPAKKENPPSRSRSQREQPLSSPRDSGVRIPKGNRGDLSVMEDGLQPAGTEQARRADAASSKTSRHLVDTAGPSKDPPRLEQWLNQVEAYVAEQKRAAGGDAGKEETQVASLAKGKSRPDKMAAEEEEEEVDGEPEEEDEEGFDYVPVFDQLVNWEQTFSASNLDFHVLRTDWIDLKCNTSGNLLLKEREALEVTRVFLKKLNQRIKGRFQLQRIVNVEKRQDRMRGSRYLLELELLEQGERLVRFSEYIFARGWQGVGGDEQEERNMRNLAWGRRRHLMAVAKEPELCWPQGFSWNHRAVVHFVVPVKNQARWVLQFISDMEELFRVTKDPYFNVIITDYSSDDMNVETALKRSSLRSYRYLKLMGNFERSAGLQAGIDLVTDPHSIIFLCDLHIHFPPGIIDSIRKHCVEGKMAFAPMVMRLHCGMSPQSPDGYWEVNGFGLLGIYKSDLDKIGGMNTKEFRDRWGGEDWELLDRILQAGLEVERLSLRNFFHWFHSKRGMWNRRQLKTL", "length": 1047, "header": "tr|A0A8V0YH22-1|A0A8V0YH22_CHICK Isoform 1 of Beta-1,4-N-acetylgalactosaminyltransferase OS=Gallus gallus OX=9031 GN=B4GALNT3 PE=3 SV=1 CANONICAL=A0A8V0YH22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR5/entry", "sequence": { "sequence": "MYVELCYATRYESWRELAKVLADPNVPGGDLSLPFYYSQKVGHQNQEHQRSGRNKSNYAAMNNPVPWMPEFQGQANLHVFEDWCGSSTEQLRRNLHFPLYPHTRTVLKKLAVSPKWTNYGLRIFGYLHPFTDGEFQFAIAADDNAEFWLSSDEKTSGLQLLASVGKTGKEWTAPGEFGKFWSQQSKVVRLSAAGRYYFEVLHKQDDKGTDHVEVAWKLNDPDAKFKVIDSQYLSLFANETLLKMDEVGHIPQTLASHKRRATDSTGSKAHPADMLKPDPRDTLYKVPLLSKSRLRRALPDCPYKPSYLVNGFPLQRYQGLQFIHLSFVYPNDYSRLSHMEKENKCFYQENPYYLERFGFYKYIKMDRRKQSLDSEEKTEQPGFQEGNLDDLQYGEQDVESTVSPAHPNMQRAEPADTAPGTVVGSHRVYEDYSLREHRRLLSVGDIGEVTQRRRTKKSGVKTALLAPANQSLSRAGPERNPATKRPHLKAGVKDNSRSPPQHARAAQGRAPAKKENPPSRSRSQREQPLSSPRDSGVRIPKGNRGDLSVMEDGLQPAGTEQARRADAASSKTSRHLVDTAGPSKDPPRLEQWLNQVEAYVAEQKRAAGGDAGKEETQVASLAKGKSRPDKMAAEEEEEEVDGEPEEEDEEGFDYVPVFDQLVNWEQTFSASNLDFHVLRTDWIDLKCNTSGNLLLKEREALEVTRVFLKKLNQRIKGRFQLQRIVNVEKRQDRMRGSRYLLELELLEQGERLVRFSEYIFARGWQGVGGDEQEERNMRNLAWGRRRHLMAVAKEPELCWPQGFSWNHRAVVHFVVPVKNQARWVLQFISDMEELFRVTKDPYFNVIITDYSSDDMNVETALKRSSLRSYRYLKLMGNFERSAGLQAGIDLVTDPHSIIFLCDLHIHFPPGIIDSIRKHCVEGKMAFAPMVMRLHCGMSPQSPDGYWEVNGFGLLGIYKSDLDKIGGMNTKEFRDRWGGEDWELLDRILQAGLEVERLSLRNFFHWFHSKRGMWNRRQLKTL", "length": 1021, "header": "tr|A0A8V0YDR5-1|A0A8V0YH22_CHICK Computationally mapped isoform of Beta-1,4-N-acetylgalactosaminyltransferase OS=Gallus gallus OX=9031 GN=B4GALNT3 PE=3 SV=1 CANONICAL=A0A8V0YH22-1" }, "locus": { "chromosome": "1", "start_pos": 60413975, "end_pos": 60358956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029393.1", "url": "https://www.ensembl.org/id/ENSGALT00010029393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017072.1", "url": "https://www.ensembl.org/id/ENSGALP00010017072.1" } ] } }, { "isoform_ac": "A0A8V0YH22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22/entry", "sequence": { "sequence": "MERCSRDGNLIPKCMRWSKANIPDSQNKTQSKHSQGYESWRELAKVLADPNVPGGDLSLPFYYSQKVGHQNQEHQRSGRNKSNYAAMNNPVPWMPEFQGQANLHVFEDWCGSSTEQLRRNLHFPLYPHTRTVLKKLAVSPKWTNYGLRIFGYLHPFTDGEFQFAIAADDNAEFWLSSDEKTSGLQLLASVGKTGKEWTAPGEFGKFWSQQSKVVRLSAAGRYYFEVLHKQDDKGTDHVEVAWKLNDPDAKFKVIDSQYLSLFANETLLKMDEVGHIPQTLASHKRRATDSTGSKAHPADMLKPDPRDTLYKVPLLSKSRLRRALPDCPYKPSYLVNGFPLQRYQGLQFIHLSFVYPNDYSRLSHMEKENKCFYQENPYYLERFGFYKYIKMDRRKQSLDSEEKTEQPGFQEGNLDDLQYGEQDVESTVSPAHPNMQRAEPADTAPGTVVGSHRVYEDYSLREHRRLLSVGDIGEVTQRRRTKKSGVKTALLAPANQSLSRAGPERNPATKRPHLKAGVKDNSRSPPQHARAAQGRAPAKKENPPSRSRSQREQPLSSPRDSGVRIPKGNRGDLSVMEDGLQPAGTEQARRADAASSKTSRHLVDTAGPSKDPPRLEQWLNQVEAYVAEQKRAAGGDAGKEETQVASLAKGKSRPDKMAAEEEEEEVDGEPEEEDEEGFDYVPVFDQLVNWEQTFSASNLDFHVLRTDWIDLKCNTSGNLLLKEREALEVTRVFLKKLNQRIKGRFQLQRIVNVEKRQDRMRGSRYLLELELLEQGERLVRFSEYIFARGWQGVGGDEQEERNMRNLAWGRRRHLMAVAKEPELCWPQGFSWNHRAVVHFVVPVKNQARWVLQFISDMEELFRVTKDPYFNVIITDYSSDDMNVETALKRSSLRSYRYLKLMGNFERSAGLQAGIDLVTDPHSIIFLCDLHIHFPPGIIDSIRKHCVEGKMAFAPMVMRLHCGMSPQSPDGYWEVNGFGLLGIYKSDLDKIGGMNTKEFRDRWGGEDWELLDRILQAGLEVERLSLRNFFHWFHSKRGMWNRRQLKTL", "length": 1047, "header": "tr|A0A8V0YH22-1|A0A8V0YH22_CHICK Isoform 1 of Beta-1,4-N-acetylgalactosaminyltransferase OS=Gallus gallus OX=9031 GN=B4GALNT3 PE=3 SV=1 CANONICAL=A0A8V0YH22-1" }, "locus": { "chromosome": "1", "start_pos": 60413975, "end_pos": 60368263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029391.1", "url": "https://www.ensembl.org/id/ENSGALT00010029391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017071.1", "url": "https://www.ensembl.org/id/ENSGALP00010017071.1" } ] } }, { "isoform_ac": "A0A8V0YLU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU8/entry", "sequence": { "sequence": "MFVCTGGGNARPGDARCWPGNGYESWRELAKVLADPNVPGGDLSLPFYYSQKVGHQNQEHQRSGRNKSNYAAMNNPVPWMPEFQGQANLHVFEDWCGSSTEQLRRNLHFPLYPHTRTVLKKLAVSPKWTNYGLRIFGYLHPFTDGEFQFAIAADDNAEFWLSSDEKTSGLQLLASVGKTGKEWTAPGEFGKFWSQQSKVVRLSAAGRYYFEVLHKQDDKGTDHVEVAWKLNDPDAKFKVIDSQYLSLFANETLLKMDEVGHIPQTLASHKRRATDSTGSKAHPADMLKPDPRDTLYKVPLLSKSRLRRALPDCPYKPSYLVNGFPLQRYQGLQFIHLSFVYPNDYSRLSHMEKENKCFYQENPYYLERFGFYKYIKMDRRKQSLDSEEKTEQPGFQEGNLDDLQYGEQDVESTVSPAHPNMQRAEPADTAPGTVVGSHRVYEDYSLREHRRLLSVGDIGEVTQRRRTKKSGVKTALLAPANQSLSRAGPERNPATKRPHLKAGVKDNSRSPPQHARAAQGRAPAKKENPPSRSRSQREQPLSSPRDSGVRIPKGNRGDLSVMEDGLQPAGTEQARRADAASSKTSRHLVDTAGPSKDPPRLEQWLNQVEAYVAEQKRAAGGDAGKEETQVASLAKGKSRPDKMAAEEEEEEVDGEPEEEDEEGFDYVPVFDQLVNWEQTFSASNLDFHVLRTDWIDLKCNTSGNLLLKEREALEVTRVFLKKLNQRIKGRFQLQRIVNVEKRQDRMRGSRYLLELELLEQGERLVRFSEYIFARGWQGVGGDEQEERNMRNLAWGRRRHLMAVAKEPELCWPQGFSWNHRAVVHFVVPVKNQARWVLQFISDMEELFRVTKDPYFNVIITDYSSDDMNVETALKRSSLRSYRYLKLMGNFERSAGLQAGIDLVTDPHSIIFLCDLHIHFPPGIIDSIRKHCVEGKMAFAPMVMRLHCGMSPQSPDGYWEVNGFGLLGIYKSDLDKIGGMNTKEFRDRWGGEDWELLDRILQAGLEVERLSLRNFFHWFHSKRGMWNRRQLKTL", "length": 1033, "header": "tr|A0A8V0YLU8-1|A0A8V0YLU8_CHICK Computationally mapped isoform of Beta-1,4-N-acetylgalactosaminyltransferase OS=Gallus gallus OX=9031 GN=B4GALNT3 PE=3 SV=1 CANONICAL=A0A8V0YH22-1" }, "locus": { "chromosome": "1", "start_pos": 60413975, "end_pos": 60356605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029398.1", "url": "https://www.ensembl.org/id/ENSGALT00010029398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017075.1", "url": "https://www.ensembl.org/id/ENSGALP00010017075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0033842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ], "pmid": "" }, { "name": "acetylgalactosaminyltransferase activity", "id": "GO:0008376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20493", "name": "", "equation": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YH22-1", "A0A8V0ZM09-1" ], "evidence": [ { "id": "20493", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20493" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YH22", "gene_name": "B4GALNT3", "activity": [ { "ec_number": "2.4.1.244", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ] }, { "ec_number": "2.4.1.244", "activity": "", "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" } ] } ] }, { "uniprot_ac": "A0A8V0ZM09", "gene_name": "B4GALNT4", "activity": [ { "ec_number": "2.4.1.244", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "A0A8V0ZM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM09" } ] }, { "ec_number": "2.4.1.244", "activity": "", "evidence": [ { "id": "A0A8V0ZM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM09" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH22" }, { "id": "PS51820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PA14", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 257, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.244", "ec_name": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "2.4.1.244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.244" }, { "id": "2.4.1.244", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.244" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YF14-1", "uniprot_ac": "A0A8V0YF14", "uniprot_id": "A0A8V0YF14_CHICK", "mass": { "chemical_mass": 43782.0, "monoisotopic_mass": 43782.0 }, "refseq": { "ac": "XP_001233320", "name": "carbonic anhydrase 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233320" }, "gene_names": [ { "name": "CA9", "type": "recommended", "evidence": [ { "id": "A0A8V0YF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ] }, { "name": "CA9", "type": "synonym", "evidence": [ { "id": "XP_001233320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233320" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase", "type": "recommended", "evidence": [ { "id": "A0A8V0YF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14/entry#names_and_taxonomy" } ] }, { "name": "carbonic anhydrase 9", "type": "synonym", "evidence": [ { "id": "XP_001233320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233320" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233320.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233320" } ] }, { "annotation": "Reversible hydration of carbon dioxide.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14#function" }, { "database": "UniProtKB", "id": "RU367011", "url": "https://www.uniprot.org/uniprotkb/RU367011#function" }, { "database": "UniProtKB", "id": "A0A8V0YDU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14", "locus": { "chromosome": "Z", "start_pos": 9779343, "end_pos": 9789503, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012303", "url": "https://www.ensembl.org/id/ENSGALG00010012303" } ] } } ], "crossref": [ { "id": "A0A8V0YF14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF14", "database": "AlphaFoldDB", "categories": [] }, { "id": "770004", "url": "https://www.ncbi.nlm.nih.gov/gene/770004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770004", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770004", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNFRATQ", "url": "https://omabrowser.org/oma/group/MNFRATQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDU8", "url": "https://www.orthodb.org/?gene=A0A8V0YDU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF14", "url": "https://www.orthodb.org/?gene=A0A8V0YF14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1475029", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1475029", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10748", "url": "https://www.rhea-db.org/rhea/10748", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYVRQSRPAGSRGPSRTPHLLEMNRTALRVCVLLLAGLGRAAGGQEHDHNDENAPHSAEKGPSDSHWSYEDPGQWAKHFPACSGTMQSPININTETTIFSPQLRPIQLSGYSLPASQMLALKNNGHTVVLKLPESLAITGGYAQQYRAVQLHLHWGSPSNPGSEHTVDHKRFAGELHVVHYNTKYENFEAAVTQPDGLAVLGVFLEVGPRENPYYQQILEHLRSIQEEDGEVFVPGFNIAGLLPDNLHLYFHYNGSLTTPPCLESVKWTVFNQTVMLSKEQMSVLVSSLQTDDNHLLMNNFRQDQSLHRRWVLASFEPSSSRDRQVPAGGSSSVTAGHTSSFHAGDVLAVLFGVLFAITMLAFLLYVYKNRSQNARLDSPTKSKVIYTAATAENTA", "length": 396, "header": "tr|A0A8V0YF14-1|A0A8V0YF14_CHICK Isoform 1 of Carbonic anhydrase OS=Gallus gallus OX=9031 GN=CA9 PE=1 SV=1 CANONICAL=A0A8V0YF14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDU8/entry", "sequence": { "sequence": "MYVRQSRPAGSRGPSRTPHLLEMNRTALRVCVLLLAGLGRAAGGQEHDHNDENAPHSAEKGPSDSHWSYEDPGQWAKHFPACSGTMQSPININTETTIFSPQLRPIQLSGYSLPASQMLALKNNGHTVVLKLPESLAITGGYAQQYRAVQLHLHWGSPSNPGSEHTVDHKRFAGELHVVHYNTKYENFEAAVTQPDGLAVLGVFLEVGPRENPYYQQILEHLRSIQEEDGEVFVPGFNIAGLLPDNLHLYFHYNGSLTTPPCLESVKWTVFNQTVMLSKEQMSVLVSSLQTDDNHLLMNNFRQDQSLHRRWVLASFEPSSSRDRQVPAAGHTSSFHAGDVLAVLFGVLFAITMLAFLLYVYKNRSQNARLDSPTKSKVIYTAATAENTA", "length": 389, "header": "tr|A0A8V0YDU8-1|A0A8V0YF14_CHICK Computationally mapped isoform of Carbonic anhydrase OS=Gallus gallus OX=9031 GN=CA9 PE=1 SV=1 CANONICAL=A0A8V0YF14-1" }, "locus": { "chromosome": "Z", "start_pos": 9789272, "end_pos": 9779461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029450.1", "url": "https://www.ensembl.org/id/ENSGALT00010029450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017110.1", "url": "https://www.ensembl.org/id/ENSGALP00010017110.1" } ] } }, { "isoform_ac": "A0A8V0YF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14/entry", "sequence": { "sequence": "MYVRQSRPAGSRGPSRTPHLLEMNRTALRVCVLLLAGLGRAAGGQEHDHNDENAPHSAEKGPSDSHWSYEDPGQWAKHFPACSGTMQSPININTETTIFSPQLRPIQLSGYSLPASQMLALKNNGHTVVLKLPESLAITGGYAQQYRAVQLHLHWGSPSNPGSEHTVDHKRFAGELHVVHYNTKYENFEAAVTQPDGLAVLGVFLEVGPRENPYYQQILEHLRSIQEEDGEVFVPGFNIAGLLPDNLHLYFHYNGSLTTPPCLESVKWTVFNQTVMLSKEQMSVLVSSLQTDDNHLLMNNFRQDQSLHRRWVLASFEPSSSRDRQVPAGGSSSVTAGHTSSFHAGDVLAVLFGVLFAITMLAFLLYVYKNRSQNARLDSPTKSKVIYTAATAENTA", "length": 396, "header": "tr|A0A8V0YF14-1|A0A8V0YF14_CHICK Isoform 1 of Carbonic anhydrase OS=Gallus gallus OX=9031 GN=CA9 PE=1 SV=1 CANONICAL=A0A8V0YF14-1" }, "locus": { "chromosome": "Z", "start_pos": 9789272, "end_pos": 9779461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029446.1", "url": "https://www.ensembl.org/id/ENSGALT00010029446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017108.1", "url": "https://www.ensembl.org/id/ENSGALP00010017108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770004", "resource": "KEGG Pathway" }, { "id": "R-GGA-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BPA4-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPITFWLGTYLPLTPPHSHLAIGEGAQGQLDPQDFGSISKRPFCESACSPPGLLLPHPPPISYARTARTHCVPGHPTVSHMAPLCPSPRLPLWIPAPAPGPAVQLLLLLLLLVPAHPQKLLWMQGAPTTGGDSSGEDDPLGEEDLPSEEDIPEEEDSPEEEDLPGLKTDPGEENSLKLEDLPTVEAPRDTEGPQNNAHRDEKGDGHSHWRYGGAPPWPQVSPACAGRFQSPVDIRPELTAFCPALRPLEFLGFELPPQPKLRLCNNGHTVQLSLPSGLKMALGPGQEYRALQLHLHWGAAGRPGSEHTVDGHRFPAEIHVVHLSTAFEEFDEALGRPGGLAVLAAFLQEGPEENSAYEQLLSRLGEITEKDSETWVPGLDVSALLPSDLSRYFRYEGSLTTPPCAQGVIWTVFNQTVKLSAKQLHTLSDSLWGPDDSRLQLNFRATQPLNGRIIEASFPAGVDGSPRTVEPVHLNSCLAAGDILALVFGLLFAVTSIAFLVQMRRQQRHLSETKGSVSYHPAEVTETVA", "length": 530 }, "evidence": [ { "id": "A0A8V0YF14", "url": "https://omabrowser.org/oma/group/A0A8V0YF14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FL00-1", "protein_name": "Carbonic anhydrase", "gene_name": "Ca9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHVQPVHTVSWDTPVSCMASLGLSPWVPLLTPAPTVQLLLLLLLLVSAHPQSLSGMQGVPSLGESSSGEDDLGVEDLPSEEDTPGEADPPGGEDPPEVNSKARKEDSLALEDLPTPEAPENRQGSHRDEKGGGHSLWSYGGTLLWPQVSPACAGRFQSPVDIRLELTSFCRTLQPLELLGYELQSLPELSLCNNGHTVQLTLPPGLKMVLGPGQEYRALQLHLHWGTSDHPGSEHTVNGHRFPAEIHVVHLSTAFSELHEALGRPGGLAVLAAFLQESPEENSAYEQLLSHLEEIAEEGSKIEIPGLDVSALLPSDLSRYYRYEGSLTTPPCSQGVIWTVFNETVKLSAKQLHTLSVSLWGLRDSRLQLNFRATQPLNGRTIEASFPAVADSSPEPVHVNSCLSAGDILALVFGLLFAATSIAFLLQLRRQHRHRSGTKDGVTYSPAEMTETGA", "length": 454 }, "evidence": [ { "id": "A0A8V0YF14", "url": "https://omabrowser.org/oma/group/A0A8V0YF14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16790-1", "protein_name": "Carbonic anhydrase 9", "gene_name": "CA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHPQRLPRMQEDSPLGGGSSGEDDPLGEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA", "length": 459 }, "evidence": [ { "id": "A0A8V0YF14", "url": "https://omabrowser.org/oma/group/A0A8V0YF14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHB5-1", "protein_name": "Carbonic anhydrase 9", "gene_name": "Ca9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLGPSPWAPLSTPAPTAQLLLFLLLQVSAQPQGLSGMQGEPSLGDSSSGEDELGVDVLPSEEDAPEEADPPDGEDPPEVNSEDRMEESLGLEDLSTPEAPEHSQGSHGDEKGGGHSHWSYGGTLLWPQVSPACAGRFQSPVDIRLERTAFCRTLQPLELLGYELQPLPELSLSNNGHTVQLTLPPGLKMALGPGQEYRALQLHLHWGTSDHPGSEHTVNGHRFPAEIHVVHLSTAFSELHEALGRPGGLAVLAAFLQESPEENSAYEQLLSHLEEISEEGSKIEIPGLDVSALLPSDLSRYYRYEGSLTTPPCSQGVIWTVFNETVKLSAKQLHTLSVSLWGPRDSRLQLNFRATQPLNGRTIEASFPAAEDSSPEPVHVNSCFTAGDILALVFGLLFAVTSIAFLLQLRRQHRHRSGTKDRVSYSPAEMTETGA", "length": 437 }, "evidence": [ { "id": "A0A8V0YF14", "url": "https://omabrowser.org/oma/group/A0A8V0YF14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ], "pmid": "" }, { "name": "molecular function activator activity", "id": "GO:0140677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10748", "name": "", "equation": "hydrogencarbonate + H(+) = CO2 + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NX31-1", "A0A1D5NTS2-1", "A0A1D5P5F4-1", "A0A8V0XZG4-1", "A0A8V0YA50-1", "A0A8V0YF14-1", "A0A8V0Z0V6-1", "P07630-1", "A0A8V0ZXU7-1", "A0A8V1AKN8-1" ], "evidence": [ { "id": "10748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10748" } ] }, { "id": "R-GGA-1475017", "name": "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJK8-1", "A0A8V1AKN8-1", "A0A8V0ZXU7-1", "A0A8V0YF14-1" ], "evidence": [ { "id": "R-GGA-1475017", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1475017" } ] }, { "id": "R-GGA-1475025", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJK8-1", "A0A8V1AKN8-1", "A0A8V0ZXU7-1", "A0A8V0YF14-1" ], "evidence": [ { "id": "R-GGA-1475025", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1475025" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTS2", "gene_name": "CA3A", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A1D5NTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTS2" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A1D5NTS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTS2" } ] } ] }, { "uniprot_ac": "A0A1D5NX31", "gene_name": "CA13", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A1D5NX31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX31" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A1D5NX31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX31" } ] } ] }, { "uniprot_ac": "A0A1D5P5F4", "gene_name": "CA3B", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A1D5P5F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5F4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A1D5P5F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5F4" } ] } ] }, { "uniprot_ac": "A0A8V0XZG4", "gene_name": "CA7", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8V0XZG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZG4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0XZG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZG4" } ] } ] }, { "uniprot_ac": "A0A8V0YA50", "gene_name": "CA5A", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8V0YA50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA50" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0YA50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA50" } ] } ] }, { "uniprot_ac": "A0A8V0YF14", "gene_name": "CA9", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8V0YF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0YF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF14" } ] } ] }, { "uniprot_ac": "A0A8V0Z0V6", "gene_name": "CA6", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8V0Z0V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V6" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Z0V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V6" } ] } ] }, { "uniprot_ac": "A0A8V0ZXU7", "gene_name": "CA12", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8V0ZXU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXU7" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXU7" } ] } ] }, { "uniprot_ac": "A0A8V1AJK8", "gene_name": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKA3-1", "uniprot_ac": "A0A8V0YKA3", "uniprot_id": "A0A8V0YKA3_CHICK", "mass": { "chemical_mass": 55068.0, "monoisotopic_mass": 55068.0 }, "refseq": { "ac": "XP_422226", "name": "D-3-phosphoglycerate dehydrogenase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422226" }, "gene_names": [ { "name": "PHGDH", "type": "recommended", "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ] }, { "name": "PHGDH", "type": "synonym", "evidence": [ { "id": "XP_422226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422226" } ] } ], "protein_names": [ { "name": "D-3-phosphoglycerate dehydrogenase", "type": "recommended", "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.95", "type": "synonym", "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3/entry#names_and_taxonomy" } ] }, { "name": "D-3-phosphoglycerate dehydrogenase", "type": "synonym", "evidence": [ { "id": "XP_422226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422226" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422226.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHGDH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3", "locus": { "chromosome": "8", "start_pos": 4252503, "end_pos": 4256109, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013380", "url": "https://www.ensembl.org/id/ENSGALG00010013380" } ] } } ], "crossref": [ { "id": "A0A8V0YKA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424381", "url": "https://www.ncbi.nlm.nih.gov/gene/424381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424381", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIAGMQV", "url": "https://omabrowser.org/oma/group/NIAGMQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDX2", "url": "https://www.orthodb.org/?gene=A0A8V0YDX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJN1", "url": "https://www.orthodb.org/?gene=A0A8V0YJN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKA3", "url": "https://www.orthodb.org/?gene=A0A8V0YKA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS37", "url": "https://www.orthodb.org/?gene=A0A8V0YS37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42938:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42938:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19304", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19304", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-977347", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977347", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12641", "url": "https://www.rhea-db.org/rhea/12641", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFAKLQKVLISDSLDPCCRDILQAGGIQVLEKPGLSKEELLQEIRDCDGLIVRSATKVSADVLEAAGRLQVVGRAGTGVDNVDVDAATRKGVLVMNTPTGNSLSAAELTCGMILCLARQIPQAAASMKEGKWDRKKYMGMELNGKTLGVLGLGRIGREVATRMQAFGMKTIGYDPIITPETSAAFGVEQLPLEQIWPRCDFITVHTPLLPSTTGLLNDSTFAKCRRGVQVVNCARGGIVDEGALLRALRSGQCGGAALDVFTQEPPKDRDLVDHPNVICCPHLGASTREAQSRCGKEIAMQIVDMATGKGLVGVVNGQALSKAFAPQTKPWIALAKALGTVLHGLAKQATGNVQVCTLGAPLKDASSYLAPAVVSGMLARGKKEATLVNAMLLAQEAGLKVTATHGDTCPEPEGLLQVALQGTPHRVTGTVQGSSPVLRELNGATFKQPAPLVGPLLIYRAKASETNALPTLTGLLGKAGIQLQSYHSSNAVVGEQWSIAGLSAPLSDLAGLKPCTAEVFQLHL", "length": 525, "header": "tr|A0A8V0YKA3-1|A0A8V0YKA3_CHICK Isoform 1 of D-3-phosphoglycerate dehydrogenase OS=Gallus gallus OX=9031 GN=PHGDH PE=1 SV=1 CANONICAL=A0A8V0YKA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX2/entry", "sequence": { "sequence": "MAFAKLQKVLISDSLDPCCRDILQAGGIQVLEKPGLSKEELLQEIRDCDGLIVRSATKVSADVLEAAGRLQVVGRAGTGVDNVDVDAATRKGVLVMNTPTGNSLSAAELTCGMILCLARQIPQAAASMKEGKWDRKKYMGMELNGKTLGVLGLGRIGREVATRMQAFGMKTIGYDPIITPETSAAFGVEQLPLEQIWPRCDFITVHTPLLPSTTGLLNDSTFAKCRRGVQVVNCARGGIVDEGALLRALRSGQCGGAALDVFTQEPPKDRDLVDHPNVICCPHLGASTREAQSRCGKEIAMQIVDMATGKGLVGVVNGQALSKAFAPQTKPWIALAKQATGNVQVCTLGAPLKDASSYLAPAVVSGMLARGKKEATLVNAMLLAQEAGLKVTATHGDTCPEPEGLLQVALQGTPHRVTGTVQGSSPVLRELNGATFKQPAPLVGPLLIYRAKASETNALPTLTGLLGKAGIQLQSYHSSNAVVGEQWSIAGLSAPLSDLAGLKPCTAEVFQLHL", "length": 514, "header": "tr|A0A8V0YDX2-1|A0A8V0YKA3_CHICK Computationally mapped isoform of D-3-phosphoglycerate dehydrogenase OS=Gallus gallus OX=9031 GN=PHGDH PE=1 SV=1 CANONICAL=A0A8V0YKA3-1" }, "locus": { "chromosome": "8", "start_pos": 4255724, "end_pos": 4252580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032226.1", "url": "https://www.ensembl.org/id/ENSGALT00010032226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019017.1", "url": "https://www.ensembl.org/id/ENSGALP00010019017.1" } ] } }, { "isoform_ac": "A0A8V0YJN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN1/entry", "sequence": { "sequence": "MAFAKLQKVLISDSLDPCCRDILQAGGIQVLEKPGLSKEELLQEIRDCDGLIVRSATKVSADVLEAAGRLQVVGRAGTGVDNVDVDAATRKGVLVMNTPTGNSLSAAELTCGMILCLARQIPQAAASMKEGKWDRKKYMGMELNGKTLGVLGLGRIGREVATRMQAFGMKTIGYDPIITPETSAAFGVEQLPLEQIWPRCDFITVHTPLLPSTTGLLNDSTFAKCRRGVQVVNCARGGIVDEGALLRALRSGQCGGAALDVFTQEPPKDRDLVDHPNVICCPHLGASTREAQSRCGKEIAMQIVDMATGKGLVGVVNGQALSKAFAPQTKPWIALAKALGTVLHGLAKQATGNVQVCTLGAPLKDASSYLAPAVVSGMLARGKKEATLVNAMLLAQEAGLKVTATHGDTCPEPEGLLQGSSPVLRELNGATFKQPAPLVGPLLIYRAKASETNALPTLTGLLGKAGIQLQSYHSSNAVVGEQWSIAGLSAPLSDLAGLKPCTAEVFQLHL", "length": 510, "header": "tr|A0A8V0YJN1-1|A0A8V0YJN1_CHICK Computationally mapped isoform of D-3-phosphoglycerate dehydrogenase OS=Gallus gallus OX=9031 GN=PHGDH PE=1 SV=1 CANONICAL=A0A8V0YKA3-1" }, "locus": { "chromosome": "8", "start_pos": 4255724, "end_pos": 4252580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032231.1", "url": "https://www.ensembl.org/id/ENSGALT00010032231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019021.1", "url": "https://www.ensembl.org/id/ENSGALP00010019021.1" } ] } }, { "isoform_ac": "A0A8V0YKA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3/entry", "sequence": { "sequence": "MAFAKLQKVLISDSLDPCCRDILQAGGIQVLEKPGLSKEELLQEIRDCDGLIVRSATKVSADVLEAAGRLQVVGRAGTGVDNVDVDAATRKGVLVMNTPTGNSLSAAELTCGMILCLARQIPQAAASMKEGKWDRKKYMGMELNGKTLGVLGLGRIGREVATRMQAFGMKTIGYDPIITPETSAAFGVEQLPLEQIWPRCDFITVHTPLLPSTTGLLNDSTFAKCRRGVQVVNCARGGIVDEGALLRALRSGQCGGAALDVFTQEPPKDRDLVDHPNVICCPHLGASTREAQSRCGKEIAMQIVDMATGKGLVGVVNGQALSKAFAPQTKPWIALAKALGTVLHGLAKQATGNVQVCTLGAPLKDASSYLAPAVVSGMLARGKKEATLVNAMLLAQEAGLKVTATHGDTCPEPEGLLQVALQGTPHRVTGTVQGSSPVLRELNGATFKQPAPLVGPLLIYRAKASETNALPTLTGLLGKAGIQLQSYHSSNAVVGEQWSIAGLSAPLSDLAGLKPCTAEVFQLHL", "length": 525, "header": "tr|A0A8V0YKA3-1|A0A8V0YKA3_CHICK Isoform 1 of D-3-phosphoglycerate dehydrogenase OS=Gallus gallus OX=9031 GN=PHGDH PE=1 SV=1 CANONICAL=A0A8V0YKA3-1" }, "locus": { "chromosome": "8", "start_pos": 4255724, "end_pos": 4252580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032223.1", "url": "https://www.ensembl.org/id/ENSGALT00010032223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019013.1", "url": "https://www.ensembl.org/id/ENSGALP00010019013.1" } ] } }, { "isoform_ac": "A0A8V0YS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS37/entry", "sequence": { "sequence": "MAFAKLQKVLISDSLDPCCRDILQAGGIQVLEKPGLSKEELLQEIRDCDGLIVRSATKVSADVLEAAGRLQVVGRAGTGVDNVDVDAATRKGVLVMKQIPQAAASMKEGKWDRKKYMGMELNGKTLGVLGLGRIGREVATRMQAFGMKTIGYDPIITPETSAAFGVEQLPLEQIWPRCDFITVHTPLLPSTTGLLNDSTFAKCRRGVQVVNCARGGIVDEGALLRALRSGQCGGAALDVFTQEPPKDRDLVDHPNVICCPHLGASTREAQSRCGKEIAMQIVDMATGKGLVGVVNGQALSKAFAPQTKPWIALAKALGTVLHGLAKQATGNVQVCTLGAPLKDASSYLAPAVVSGMLARGKKEATLVNAMLLAQEAGLKVTATHGDTCPEPEGLLQVALQGTPHRVTGTVQGSSPVLRELNGATFKQPAPLVGPLLIYRAKASETNALPTLTGLLGKAGIQLQSYHSSNAVVGEQWSIAGLSAPLSDLAGLKPCTAEVFQLHL", "length": 503, "header": "tr|A0A8V0YS37-1|A0A8V0YKA3_CHICK Computationally mapped isoform of D-3-phosphoglycerate dehydrogenase OS=Gallus gallus OX=9031 GN=PHGDH PE=1 SV=1 CANONICAL=A0A8V0YKA3-1" }, "locus": { "chromosome": "8", "start_pos": 4255724, "end_pos": 4252580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032217.1", "url": "https://www.ensembl.org/id/ENSGALT00010032217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019007.1", "url": "https://www.ensembl.org/id/ENSGALP00010019007.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424381", "resource": "KEGG Pathway" }, { "id": "R-GGA-977347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977347", "resource": "Reactome", "description": "Serine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A5GFY8-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFANLRKVLISDSLDPCCREILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTSDVINAAKKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMILCLARQIPQATASMKDGKWERKKFMGTELNGKVLGILGLGRIGREVATRMQSFGMKTIGYDPIIAPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFALCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHEKVISCPHLGASTREAQSRCGEEIAIQFVDMVKGRSLAGVVNAQALTSAFSPHTKPWIGLAEALGALMQAWAGSPKGTIQVVTQGTSLKNSGTCLSPAVIVGLLKEASHRADVNLVNAKLLEKEAGLHVTTSHNPAAPEEQGGAECFLTVALAGAPYQAVGLVQGTAPMLHALNGAVFRPEVPLRRGLPLLLFRAQPSNPTMLPTMIGLLAEARVQLLSYQTSVVSDGETWHVMAISSLLPSLEPWKQHVTEAFQFHF", "length": 533 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QEY8-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "phgdh", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPISVKRVLISESVDPCCKSVLQENGIEVTEKQQMTKEELIAEIRNYDGLIVRSATKVTADVINAGSSLKIIGRAGTGVDNVDVDAATKRGIIVMNTPSGNTLSAAELTCALVMSLSRHIPQAVISMKDGKWDRKKFMGSELYGKVLGIVGLGRIGKEVATRMQSFGMKTIGYDPITPPEVSASWGVEQMTLDQLWPQCDYITVHTPLMASTTGLLNDASFAKCKKGVKVVNCARGGIIDEAALLRALESGQCGGAGLDVFVEEPPRERALVNHPNVISCPHLGASTKEAQARCGKDIALQIVDMATGKALVGAVNAQVLASTFSPDSQQWIRLGESMGKVLKACSASTQPCSQLHVTSLGEALKKSTGFLSSAAVVGLLTEAPHNGPNLVNALPLAKETGITVHTDHKASDEREACVMEVSVNGSRYKAVGSVQAGVPVLLELNGSVFRQPVPLTGHLLFFRANCSTEFLSSITGVLATAGVELQSFSASSSSSGGEKWYCMGISSLLGDIGALKSLVKDAAQLTV", "length": 528 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HP75-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "Phgdh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHNPVVPGDQSSGECLLTVALAGAPYQAVGLVQGTTPMLQVLNGAVFRPEVPLRRGQPLLMFRAQPSNPVMLPTMIGLLAEAGVQLLSYQTSKASDGETWHVMGLSSLLPSLEAWKQHVSEAFQFCF", "length": 533 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08651-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "Phgdh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFANLRKILISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF", "length": 533 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43175-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF", "length": 533 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O49485-1", "protein_name": "D-3-phosphoglycerate dehydrogenase 1, chloroplastic", "gene_name": "PGDH1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSATAAASSSIAVATNSLRNVTLSSRSPLPSAISVAFPSRGRNTLQRRLVLVSCSTGDGSKPTILVAEKLGDAGIKLLEDVANVDCSYNMTPEELNIKISLCDALIVRSGTKVGREVFESSHGRLKVVGRAGVGIDNVDLSAATEFGCLVVNAPTANTIAAAEHGIALMAAMARNVAQADASVKAGEWKRNKYVGVSLVGKTLAVLGFGKVGTEVARRAKGLGMRVIAHDPYAPADRAHAIGVDLVSFDEALATADFISLHMPLTPTTSKILNDETFAKMKKGVRIVNVARGGVIDEDALVRALDAGIVAQAALDVFTKEPPAKDSKLVQHERVTVTPHLGASTMEAQEGVAIEIAEAVVGALNGELAATAVNAPMVSAEVLTELKPYVVLAEKLGRLAVQLVAGGSGVKNAKITYASARATDDLDTRLLRAMITKGIIEPISDVYVNLVNADFTAKQRGLRLSEERVLLDGSPESPLETITVQLSNVESKFASSLSESGEVKVEGKVKDGVPHLTKVGSFEVDVTLEGSIILCRQVDQPGMIGTVGSILGESNVNVNFMSVGRIAPRKQAIMAIGVDDIPSKETLKKIGEIPAVEEFVFLKL", "length": 603 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q61753-1", "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "Phgdh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEAMGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHNPGVPGEQGSGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLVFRAQPSDPGMLPTMIGLLAEAGVQLLSYQTSMVSDGEPWHVMGLSSLLPSLETWKQHVLEAFQFCF", "length": 533 }, "evidence": [ { "id": "A0A8V0YKA3", "url": "https://omabrowser.org/oma/group/A0A8V0YKA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ], "pmid": "" }, { "name": "phosphoglycerate dehydrogenase activity", "id": "GO:0004617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-serine biosynthetic process", "id": "GO:0006564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12641", "name": "", "equation": "(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKA3-1" ], "evidence": [ { "id": "12641", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12641" } ] }, { "id": "R-GGA-977348", "name": "PHGDH tetramer dehydrogenates 3PG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKA3-1" ], "evidence": [ { "id": "R-GGA-977348", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977348" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKA3", "gene_name": "PHGDH", "activity": [ { "ec_number": "1.1.1.95", "activity": "(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+).", "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ] }, { "ec_number": "1.1.1.95", "activity": "", "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" }, { "id": "PF19304", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-3-phosphoglycerate dehydrogenase ASB", "eco_id": "ECO_0000259", "start_pos": 330, "end_pos": 434, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" }, { "id": "PF02826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 285, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YKA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA3" }, { "id": "PF00389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-isomer specific 2-hydroxyacid dehydrogenase catalytic", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 317, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.95", "ec_name": "(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+).", "evidence": [ { "id": "1.1.1.95", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.95" }, { "id": "1.1.1.95", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.95" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKB7-1", "uniprot_ac": "A0A8V0YKB7", "uniprot_id": "A0A8V0YKB7_CHICK", "mass": { "chemical_mass": 114821.0, "monoisotopic_mass": 114821.0 }, "refseq": {}, "gene_names": [ { "name": "ITGAV", "type": "recommended", "evidence": [ { "id": "A0A8V0YKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ] } ], "protein_names": [ { "name": "Integrin alpha-V", "type": "recommended", "evidence": [ { "id": "A0A8V0YKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7/entry#names_and_taxonomy" } ] }, { "name": "Vitronectin receptor subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITGAV", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7", "locus": { "chromosome": "7", "start_pos": 1402712, "end_pos": 1455735, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013386", "url": "https://www.ensembl.org/id/ENSGALG00010013386" } ] } } ], "crossref": [ { "id": "A0A8V0YKB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "396420", "url": "https://www.ncbi.nlm.nih.gov/gene/396420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396420", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396420", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRMQCEE", "url": "https://omabrowser.org/oma/group/GRMQCEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDX7", "url": "https://www.orthodb.org/?gene=A0A8V0YDX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP7", "url": "https://www.orthodb.org/?gene=A0A8V0YJP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKB7", "url": "https://www.orthodb.org/?gene=A0A8V0YKB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS72", "url": "https://www.orthodb.org/?gene=A0A8V0YS72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS77", "url": "https://www.orthodb.org/?gene=A0A8V0YS77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1236973", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236973", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1566948", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-210990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2173789", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-445144", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445144", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRASLLLSCALTAARAFNLDAERPAVYSGAEGSYFGFAVDFFAPDASSMFLLVGAPKANTSQSNVVEGGQVLQCNWNSNRNCQPIIFDSTGNRDFAPDDPLEFKSHQWFGASVRSKNDKILACAPLYHWRTETKQEREPVGTCYLFDGSKSVEYAPCRSTTIDADGQGFCQGGFSIDFTKGDRVLLGGPGSFYWQGQLISDRVAEILAKYDSKVYSTKYDDQLATRPASAAFDDSYLGHSALETECYMGVLFCISDFVSGVPRAARTLGMVSIYNGKNMSSMYNFTGEQMAAYFGYSVATTDINGDDYTDLFIGAPLFMDRGSDGKLQEVGQVSICLQRASGGFQIAKLNGFEIFARFGSAIAPLGDLDQDGFNDIAVAAPYGGEDKRGLVYIYNGRATGLNAVPSQILEGQWAARTMPPSFGYSLKGATDVDKNGYPDLIVGAFGVDTAVLYRARPVIRVNAALEVNPTILNPENKACSLADVKVSCFKVKFCLKADGKGKLPSSLNFQVELLLDKLKQKGAIRRALFLHSKQPSHSKNMTITKGGKMNCEELDAFLRDESEFRDKLTPITIFMEYRLDYKTAVDATGLHPILNQFIPANMSRQAHILLDCGEDNICKPKLEVSVRSDQKKIYIGDDNPLTLIVTAENQGEGAYEAELFVIVPPQADFIGVVRNNEALARLSCAFKTENQTRMVVCDLGNPMKAGTKLLAGLRFSVHQQSEMDTSVKFDLQIRSSNLFDNLSPVAFYQVDLAISAAVEIRGVSSPDHIFLPIANWQPKENPETEDDIGPLVQHIYELRNNGPSAFSKVMMTLQWPYKYKNYTLLYIVQYDIDGPMNCTSDMEINPLKIKISAPKEDEKNETFSREDNRNHRISRRDLTAIEGDVQTLGCGNADCLKIVCQVGHLERGKSAILYLKSRLWTQTFMNKENQNHSYSLQSSASFNVIEFPYKNLSFEDIHNSTVVTTNITWGIQPQPMPVPVWVIILAVLAGLLLLAVLVLVMYRMGFFKRVRPPQEEQEREQLQPHENGEGTSEA", "length": 1037, "header": "tr|A0A8V0YKB7-1|A0A8V0YKB7_CHICK Isoform 1 of Integrin alpha-V OS=Gallus gallus OX=9031 GN=ITGAV PE=1 SV=1 CANONICAL=A0A8V0YKB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX7/entry", "sequence": { "sequence": "MKAARRSRMFLLVGAPKANTSQSNVVEGGQVLQCNWNSNRNCQPIIFDSTGNRDFAPDDPLEFKSHQWFGASVRSKNDKILACAPLYHWRTETKQEREPVGTCYLFDGSKSVEYAPCRSTTIDADGQGFCQGGFSIDFTKGDRVLLGGPGSFYWQGQLISDRVAEILAKYDSKVYSTKYDDQLATRPASAAFDDSYLGYSVAVGDFSGDGIEDFVSGVPRAARTLGMVSIYNGKNMSSMYNFTGEQMAAYFGYSVATTDINGDDYTDLFIGAPLFMDRGSDGKLQEVGQVSICLQRASGGFQIAKLNGFEIFARFGSAIAPLGDLDQDGFNDIAVAAPYGGEDKRGLVYIYNGRATGLNAVPSQILEGQWAARTMPPSFGYSLKGATDVDKNGYPDLIVGAFGVDTAVLYRARPVIRVNAALEVNPTILNPENKACSLADVKVSCFKVKFCLKADGKGKLPSSLNFQVELLLDKLKQKGAIRRALFLHSKQPSHSKNMTITKGGKMNCEELDAFLRDESEFRDKLTPITIFMEYRLDYKTAVDATGLHPILNQFIPANMSRQAHILLDCGEDNICKPKLEVSVRSDQKKIYIGDDNPLTLIVTAENQGEGAYEAELFVIVPPQADFIGVVRNNEALARLSCAFKTENQTRMVVCDLGNPMKAGTKLLAGLRFSVHQQSEMDTSVKFDLQIRSSNLFDNLSPVAFYQVDLAISAAVEIRGVSSPDHIFLPIANWQPKENPETEDDIGPLVQHIYELRNNGPSAFSKVMMTLQWPYKYKNYTLLYIVQYDIDGPMNCTSDMEINPLKIKISAPKEDEKNETFSREDNRNHRISRRDLTAIEGDVQTLGCGNADCLKIVCQVGHLERGKSAILYLKSRLWTQTFMNKENQNHSYSLQSSASFNVIEFPYKNLSFEDIHNSTVVTTNITWGIQPQPMPVPVWVIILAVLAGLLLLAVLVLVMYRMGFFKRVRPPQEEQEREQLQPHENGEGTSEA", "length": 991, "header": "tr|A0A8V0YDX7-1|A0A8V0YKB7_CHICK Computationally mapped isoform of Integrin alpha-V OS=Gallus gallus OX=9031 GN=ITGAV PE=1 SV=1 CANONICAL=A0A8V0YKB7-1" }, "locus": { "chromosome": "7", "start_pos": 1449105, "end_pos": 1408003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032232.1", "url": "https://www.ensembl.org/id/ENSGALT00010032232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019022.1", "url": "https://www.ensembl.org/id/ENSGALP00010019022.1" } ] } }, { "isoform_ac": "A0A8V0YJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP7/entry", "sequence": { "sequence": "MAALRASLLLSCALTAARAFNLDAERPAVYSGAEGSYFGFAVDFFAPDASSMFLLVGAPKANTSQSNVVEGGQVLQCNWNSNRNCQPIIFDSTGNRDFAPDDPLEFKSHQWFGASVRSKNDKILACAPLYHWRTETKQEREPVGTCYLFDGSKSVEYAPCRSTTIDADGQGFCQGGFSIDFTKGDRVLLGGPGSFYWQGQLISDRVAEILAKYDSKVYSTKYDDQLATRPASAAFDDSYLGYSVAVGDFSGDGIEDFVSGVPRAARTLGMVSIYNGKNMSSMYNFTGEQMAAYFGYSVATTDINGDDYTDLFIGAPLFMDRGSDGKLQEVGQVSICLQRASGGFQIAKLNGFEIFARFGSAIAPLGDLDQDGFNDIAVAAPYGGEDKRGLVYIYNGRATGLNAVPSQILEGQWAARTMPPSFGYSLKGATDVDKNGYPDLIVGAFGVDTAVLYRARPVIRVNAALEVNPTILNPENKACSLADVKVSCFKVKFCLKADGKGKLPSSLNFQVELLLDKLKQKGAIRRALFLHSKQPSHSKNMTITKGGKMNCEELDAFLRDESEFRDKLTPITIFMEYRLDYKTAVDATGLHPILNQFIPANMSRQAHILLDCGEDNICKPKLEVSVRSDQKKIYIGDDNPLTLIVTAENQGEGAYEAELFVIVPPQADFIGVVRNNEALARLSCAFKTENQTRMVVCDLGNPMKAGTKLLAGLRFSVHQQSEMDTSVKFDLQIRSSNLFDNLSPVAFYQVDLAISAAVEIRGVSSPDHIFLPIANWQPKENPETEDDIGPLVQHIYELRNNGPSAFSKVMMTLQWPYKYKNYTLLYIVQYDIDGPMNCTSDMEINPLKIKISAPKEDEKNETFSREDNRNHRISRRDLTAIEGDVQTLGCGNADCLKIVCQVGHLERGKSAILYLKSRLWTQTFMNKENQNHSYSLQSSASFNVIEFPYKNLSFEDIHNSTVVTTNITWGIQPQPMPVPVWVIILAVLAGLLLLAVLVLVMYRMGFFKRVRPPQEEQEREQLQPHENGEGTSEA", "length": 1034, "header": "tr|A0A8V0YJP7-1|A0A8V0YJP7_CHICK Computationally mapped isoform of Integrin alpha-V OS=Gallus gallus OX=9031 GN=ITGAV PE=1 SV=1 CANONICAL=A0A8V0YKB7-1" }, "locus": { "chromosome": "7", "start_pos": 1451254, "end_pos": 1408003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032246.1", "url": "https://www.ensembl.org/id/ENSGALT00010032246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019036.1", "url": "https://www.ensembl.org/id/ENSGALP00010019036.1" } ] } }, { "isoform_ac": "A0A8V0YKB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7/entry", "sequence": { "sequence": "MAALRASLLLSCALTAARAFNLDAERPAVYSGAEGSYFGFAVDFFAPDASSMFLLVGAPKANTSQSNVVEGGQVLQCNWNSNRNCQPIIFDSTGNRDFAPDDPLEFKSHQWFGASVRSKNDKILACAPLYHWRTETKQEREPVGTCYLFDGSKSVEYAPCRSTTIDADGQGFCQGGFSIDFTKGDRVLLGGPGSFYWQGQLISDRVAEILAKYDSKVYSTKYDDQLATRPASAAFDDSYLGHSALETECYMGVLFCISDFVSGVPRAARTLGMVSIYNGKNMSSMYNFTGEQMAAYFGYSVATTDINGDDYTDLFIGAPLFMDRGSDGKLQEVGQVSICLQRASGGFQIAKLNGFEIFARFGSAIAPLGDLDQDGFNDIAVAAPYGGEDKRGLVYIYNGRATGLNAVPSQILEGQWAARTMPPSFGYSLKGATDVDKNGYPDLIVGAFGVDTAVLYRARPVIRVNAALEVNPTILNPENKACSLADVKVSCFKVKFCLKADGKGKLPSSLNFQVELLLDKLKQKGAIRRALFLHSKQPSHSKNMTITKGGKMNCEELDAFLRDESEFRDKLTPITIFMEYRLDYKTAVDATGLHPILNQFIPANMSRQAHILLDCGEDNICKPKLEVSVRSDQKKIYIGDDNPLTLIVTAENQGEGAYEAELFVIVPPQADFIGVVRNNEALARLSCAFKTENQTRMVVCDLGNPMKAGTKLLAGLRFSVHQQSEMDTSVKFDLQIRSSNLFDNLSPVAFYQVDLAISAAVEIRGVSSPDHIFLPIANWQPKENPETEDDIGPLVQHIYELRNNGPSAFSKVMMTLQWPYKYKNYTLLYIVQYDIDGPMNCTSDMEINPLKIKISAPKEDEKNETFSREDNRNHRISRRDLTAIEGDVQTLGCGNADCLKIVCQVGHLERGKSAILYLKSRLWTQTFMNKENQNHSYSLQSSASFNVIEFPYKNLSFEDIHNSTVVTTNITWGIQPQPMPVPVWVIILAVLAGLLLLAVLVLVMYRMGFFKRVRPPQEEQEREQLQPHENGEGTSEA", 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"length": 989, "header": "tr|A0A8V0YS72-1|A0A8V0YKB7_CHICK Computationally mapped isoform of Integrin alpha-V OS=Gallus gallus OX=9031 GN=ITGAV PE=1 SV=1 CANONICAL=A0A8V0YKB7-1" }, "locus": { "chromosome": "7", "start_pos": 1452051, "end_pos": 1408003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032253.1", "url": "https://www.ensembl.org/id/ENSGALT00010032253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019043.1", "url": "https://www.ensembl.org/id/ENSGALP00010019043.1" } ] } }, { "isoform_ac": "A0A8V0YS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS77/entry", "sequence": { "sequence": "MGAHSWMFLLVGAPKANTSQSNVVEGGQVLQCNWNSNRNCQPIIFDSTGNRDFAPDDPLEFKSHQWFGASVRSKNDKILACAPLYHWRTETKQEREPVGTCYLFDGSKSVEYAPCRSTTIDADGQGFCQGGFSIDFTKGDRVLLGGPGSFYWQGQLISDRVAEILAKYDSKVYSTKYDDQLATRPASAAFDDSYLGYSVAVGDFSGDGIEDFVSGVPRAARTLGMVSIYNGKNMSSMYNFTGEQMAAYFGYSVATTDINGDDYTDLFIGAPLFMDRGSDGKLQEVGQVSICLQRASGGFQIAKLNGFEIFARFGSAIAPLGDLDQDGFNDIAVAAPYGGEDKRGLVYIYNGRATGLNAVPSQILEGQWAARTMPPSFGYSLKGATDVDKNGYPDLIVGAFGVDTAVLYRARPVIRVNAALEVNPTILNPENKACSLADVKVSCFKVKFCLKADGKGKLPSSLNFQVELLLDKLKQKGAIRRALFLHSKQPSHSKNMTITKGGKMNCEELDAFLRDESEFRDKLTPITIFMEYRLDYKTAVDATGLHPILNQFIPANMSRQAHILLDCGEDNICKPKLEVSVRSDQKKIYIGDDNPLTLIVTAENQGEGAYEAELFVIVPPQADFIGVVRNNEALARLSCAFKTENQTRMVVCDLGNPMKAGTKLLAGLRFSVHQQSEMDTSVKFDLQIRSSNLFDNLSPVAFYQVDLAISAAVEIRGVSSPDHIFLPIANWQPKENPETEDDIGPLVQHIYELRNNGPSAFSKVMMTLQWPYKYKNYTLLYIVQYDIDGPMNCTSDMEINPLKIKISAPKEDEKNETFSREDNRNHRISRRDLTAIEGDVQTLGCGNADCLKIVCQVGHLERGKSAILYLKSRLWTQTFMNKENQNHSYSLQSSASFNVIEFPYKNLSFEDIHNSTVVTTNITWGIQPQPMPVPVWVIILAVLAGLLLLAVLVLVMYRMGFFKRVRPPQEEQEREQLQPHENGEGTSEA", "length": 989, "header": "tr|A0A8V0YS77-1|A0A8V0YKB7_CHICK Computationally mapped isoform of Integrin alpha-V OS=Gallus gallus OX=9031 GN=ITGAV PE=1 SV=1 CANONICAL=A0A8V0YKB7-1" }, "locus": { "chromosome": "7", "start_pos": 1455543, "end_pos": 1408003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032259.1", "url": "https://www.ensembl.org/id/ENSGALT00010032259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019048.1", "url": "https://www.ensembl.org/id/ENSGALP00010019048.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396420", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396420", "resource": "KEGG Pathway" }, { "id": "R-GGA-1236973", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236973", "resource": "Reactome", "description": "Cross-presentation of particulate exogenous antigens (phagosomes)" }, { "id": "R-GGA-1566948", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "resource": "Reactome", "description": "Elastic fibre formation" }, { "id": "R-GGA-210990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "resource": "Reactome", "description": "PECAM1 interactions" }, { "id": "R-GGA-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-2173789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173789", "resource": "Reactome", "description": "TGF-beta receptor signaling activates SMADs" }, { "id": "R-GGA-3000170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000170", "resource": 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"A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin complex", "id": "GO:0008305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008305", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "alphav-beta3 integrin-IGF-1-IGF1R complex", "id": "GO:0035867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "filopodium membrane", "id": "GO:0031527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "microvillus membrane", "id": "GO:0031528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin alphav-beta3 complex", "id": "GO:0034683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin alphav-beta5 complex", "id": "GO:0034684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034684", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin alphav-beta6 complex", "id": "GO:0034685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin alphav-beta8 complex", "id": "GO:0034686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "alphav-beta3 integrin-HMGB1 complex", "id": "GO:0035868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin alphav-beta1 complex", "id": "GO:0034682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 29, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": 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mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "negative regulation of macrophage derived foam cell differentiation", "id": "GO:0010745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "positive regulation of osteoblast proliferation", "id": "GO:0033690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "ERK1 and ERK2 cascade", "id": "GO:0070371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB7" } ], "pmid": "" }, { "name": "apolipoprotein A-I-mediated signaling pathway", "id": "GO:0038027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038027", "evidence": [ { "database": 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analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015137131.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137131" } ] }, { "annotation": "Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. 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Classification" ] }, { "id": "A0A8V0YFK0", "url": "https://www.orthodb.org/?gene=A0A8V0YFK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN1", "url": "https://www.orthodb.org/?gene=A0A8V0YHN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN6", "url": "https://www.orthodb.org/?gene=A0A8V0YHN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP2", "url": "https://www.orthodb.org/?gene=A0A8V0YHP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMG4", "url": "https://www.orthodb.org/?gene=A0A8V0YMG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GI10", "url": "https://www.orthodb.org/?gene=R4GI10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10173:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10173:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5676934", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5676934", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21260", "url": "https://www.rhea-db.org/rhea/21260", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24164", "url": "https://www.rhea-db.org/rhea/24164", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI10", "url": "https://www.uniprot.org/uniprotkb/R4GI10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI10-1", "url": "https://www.uniprot.org/uniprotkb/R4GI10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAAPPPPPLLSALVLALAAAAGAAGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 184, "header": "tr|A0A8V0YHP2-1|A0A8V0YHP2_CHICK Isoform 1 of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE8/entry", "sequence": { "sequence": "MPPWAAGPSPLSRGAEGGWGGVGAAAAAPSGLPSCALRRRRRRSSPHSSWRWRPPQEPQLLPLFFASGFVGEDITVMSAFNLLHLVTKSQPVALRACGLPSAFRSTYHQRCMITGGSSRGLKENKRSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 284, "header": "tr|A0A8V0YEE8-1|A0A8V0YHP2_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34114286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029725.1", "url": "https://www.ensembl.org/id/ENSGALT00010029725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017301.1", "url": "https://www.ensembl.org/id/ENSGALP00010017301.1" } ] } }, { "isoform_ac": "A0A8V0YFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK0/entry", "sequence": { "sequence": "SEELYCSLQLEGALWRGETGEFLFYAEERLCGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 190, "header": "tr|A0A8V0YFK0-1|A0A8V0YFK0_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34121483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029715.1", "url": "https://www.ensembl.org/id/ENSGALT00010029715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017294.1", "url": "https://www.ensembl.org/id/ENSGALP00010017294.1" } ] } }, { "isoform_ac": "A0A8V0YHN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN1/entry", "sequence": { "sequence": "MKEERRKQKLYCSLQLEGALWRGETGEFLFYAEERLCGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 196, "header": "tr|A0A8V0YHN1-1|A0A8V0YHN1_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34122642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029711.1", "url": "https://www.ensembl.org/id/ENSGALT00010029711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017290.1", "url": "https://www.ensembl.org/id/ENSGALP00010017290.1" } ] } }, { "isoform_ac": "A0A8V0YHN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN6/entry", "sequence": { "sequence": "RGVAGPAQVQPRAEPVVILTAGLAEQLLLPLFFASGFVGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 197, "header": "tr|A0A8V0YHN6-1|A0A8V0YHN6_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34118020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029716.1", "url": "https://www.ensembl.org/id/ENSGALT00010029716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017295.1", "url": "https://www.ensembl.org/id/ENSGALP00010017295.1" } ] } }, { "isoform_ac": "A0A8V0YHP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2/entry", "sequence": { "sequence": "MRAAPPPPPLLSALVLALAAAAGAAGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 184, "header": "tr|A0A8V0YHP2-1|A0A8V0YHP2_CHICK Isoform 1 of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34114387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029723.1", "url": "https://www.ensembl.org/id/ENSGALT00010029723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017300.1", "url": "https://www.ensembl.org/id/ENSGALP00010017300.1" } ] } }, { "isoform_ac": "A0A8V0YMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG4/entry", "sequence": { "sequence": "MRAAPPPPPLLSALVLALAAAAGAAELYCSLQLEGALWRGETGEFLFYAEERLCGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 213, "header": "tr|A0A8V0YMG4-1|A0A8V0YMG4_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34114387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029719.1", "url": "https://www.ensembl.org/id/ENSGALT00010029719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017298.1", "url": "https://www.ensembl.org/id/ENSGALP00010017298.1" } ] } }, { "isoform_ac": "R4GI10-1", "url": "https://www.uniprot.org/uniprotkb/R4GI10/entry", "sequence": { "sequence": "MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKDCKVVFSQEELRKRLTPLQYHVTQEKGTESAFEGEYTHHKAQGIYKCVVCGTPLFKSETKFDSNSGWPSFYDVISPDTITLTDDFSYGMHRIEISCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFKPAEKNSAGEGSGSTRPAQTGKAEL", "length": 184, "header": "tr|R4GI10-1|R4GI10_CHICK Computationally mapped isoform of Peptide-methionine (R)-S-oxide reductase OS=Gallus gallus OX=9031 GN=MSRB3 PE=1 SV=1 CANONICAL=A0A8V0YHP2-1" }, "locus": { "chromosome": "1", "start_pos": 34195600, "end_pos": 34132049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029721.1", "url": "https://www.ensembl.org/id/ENSGALT00010029721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017299.1", "url": "https://www.ensembl.org/id/ENSGALP00010017299.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417833", "resource": "KEGG Pathway" }, { "id": "R-GGA-5676934", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5676934", "resource": "Reactome", "description": "Protein repair" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "peptide-methionine (R)-S-oxide reductase activity", "id": "GO:0033743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" }, { "name": "L-methionine-(R)-S-oxide reductase activity", "id": "GO:0033745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" }, { "name": "protein repair", "id": "GO:0030091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21260", "name": "", "equation": "[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHP2-1" ], "evidence": [ { "id": "21260", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21260" } ] }, { "id": "24164", "name": "", "equation": "L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHP2-1" ], "evidence": [ { "id": "24164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24164" } ] }, { "id": "R-GGA-5676917", "name": "MRSBs reduce L-methyl-(R)-S-oxide to L-methionine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5676932" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHP2-1" ], "evidence": [ { "id": "R-GGA-5676917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5676917" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5676932", "participant_name": "L-methionine (R)-S-oxide [cytosol]", "crossref": [ { "id": "49032", "database": "ChEBI", "url": "" }, { "id": "C15998", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003861729", "database": "ZINC", "url": "" }, { "id": "ZINC000001529567", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YHP2", "gene_name": "MSRB3", "activity": [ { "ec_number": "1.8.4.12", "activity": "L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol.", "evidence": [ { "id": "A0A8V0YHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ] }, { "ec_number": "1.8.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP2" }, { "id": "PS51790", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51790" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MsrB", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 162, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.8.4.12", "ec_name": "L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol.", "evidence": [ { "id": "1.8.4.12", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.12" }, { "id": "1.8.4.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.8.4.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, 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"MMKFKPNQTRTYDREGYKKRAACLCFRSEREDEVSPVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLSCSPTNGNSVVPPLPDNNSLYVTSAQTSGLPSTVR", "length": 183, "header": "tr|A0A8V0YKW8-1|A0A8V0YKW8_CHICK Isoform 1 of diphosphoinositol-polyphosphate diphosphatase OS=Gallus gallus OX=9031 GN=NUDT4 PE=3 SV=1 CANONICAL=A0A8V0YKW8-1" }, "locus": { "chromosome": "1", "start_pos": 44888244, "end_pos": 44867957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032479.1", "url": "https://www.ensembl.org/id/ENSGALT00010032479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019226.1", "url": "https://www.ensembl.org/id/ENSGALP00010019226.1" } ] } }, { "isoform_ac": "A0A8V0YSP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSP6/entry", "sequence": { "sequence": "MMKFKPNQTRTYDREGYKKRAACLCFRSEREDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEELYYLCFSWHALKTLSFVVEAWELDVNVGCLKFPCLLVSE", "length": 109, "header": "tr|A0A8V0YSP6-1|A0A8V0YKW8_CHICK Computationally mapped isoform of diphosphoinositol-polyphosphate diphosphatase OS=Gallus gallus OX=9031 GN=NUDT4 PE=3 SV=1 CANONICAL=A0A8V0YKW8-1" }, "locus": { "chromosome": "1", "start_pos": 44880189, "end_pos": 44867957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032460.1", "url": "https://www.ensembl.org/id/ENSGALT00010032460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019210.1", "url": "https://www.ensembl.org/id/ENSGALP00010019210.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1855167", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855167", "resource": "Reactome", "description": "Synthesis of pyrophosphates in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "diphosphoinositol-polyphosphate diphosphatase activity", "id": "GO:0008486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "endopolyphosphatase activity", "id": "GO:0000298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "bis(5'-adenosyl)-hexaphosphatase activity", "id": "GO:0034431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "bis(5'-adenosyl)-pentaphosphatase activity", "id": "GO:0034432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034432", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "diphosphoinositol polyphosphate metabolic process", "id": "GO:0071543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "diadenosine pentaphosphate catabolic process", "id": "GO:1901907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901907", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "diadenosine hexaphosphate catabolic process", "id": "GO:1901909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" }, { "name": "adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "id": "GO:1901911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-1855165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855165" } ] }, { "id": "R-GGA-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-1855166", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855166" } ] }, { "id": "R-GGA-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-1855198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855198" } ] }, { "id": "R-GGA-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-2023971", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2023971" } ] }, { "id": "R-GGA-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-2023973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2023973" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKW8", "gene_name": "NUDT4", "activity": [ { "ec_number": "3.6.1.52", "activity": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ] }, { "ec_number": "3.6.1.52", "activity": "", "evidence": [ { "id": "A0A8V0YKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ] } ] }, { "uniprot_ac": "E1C4K9", "gene_name": "NUDT3", "activity": [ { "ec_number": "3.6.1.52", "activity": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "E1C4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4K9" } ] }, { "ec_number": "3.6.1.52", "activity": "", "evidence": [ { "id": "E1C4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4K9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" }, { "id": "PS51462", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nudix hydrolase", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 147, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.52", "ec_name": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "3.6.1.52", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.52" }, { "id": "3.6.1.52", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.52" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"type": "recommended", "evidence": [ { "id": "A0A8V0YKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPPNR1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05772", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05772", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771734", "url": "https://www.ncbi.nlm.nih.gov/gene/771734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771734", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK60", "url": "https://www.orthodb.org/?gene=A0A8V0YK60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK91", "url": "https://www.orthodb.org/?gene=A0A8V0YK91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKV7", "url": "https://www.orthodb.org/?gene=A0A8V0YKV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKX8", "url": "https://www.orthodb.org/?gene=A0A8V0YKX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS5", "url": "https://www.orthodb.org/?gene=A0A8V0YMS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSR6", "url": "https://www.orthodb.org/?gene=A0A8V0YSR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-391160", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391160", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYKDSSSNLRCSRVLSLLSLTPIGQTAHSTWSPQISHSCFCHGPSWLGCWRCVLSRMALNAHCIWEHCASPPPPCFPRSPHHNSTGLCAVPGGARGRQSSSSRRSPPCAGTAAAAPSLPASLRGGALPPAHLKKAAAGVPGGAPTHEFGRSQAVPGCGEPRRYRGRSRCQGNGGGAAEGRCGAERCGAERPRGRSGPGQEEPEMEPRPPAWPLLCLLLLCQSSCAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGKSSPSARLHEPEKSSGTTTTQESDPNNMTYADLNFAKEKRKSVRRVIELSQQSEYACIQGSNSSSSQPASSSDNLTYADLDMVHLSKAPRRPPPCPEESSSEYASVQIQRQ", "length": 709, "header": "tr|A0A8V0YKX8-1|A0A8V0YKX8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ6/entry", "sequence": { "sequence": "MQWEEPEMEPRPPAWPLLCLLLLCQSSCAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGKSSPSARLHEPEKSSGTTTTQESDPNNMTYADLNFAKEKRKSVRRVIELSQQSEYACIQGSNSSSSQPASSSDNLTYADLDMVHLSKAPRRPPPCPEESSSEYASVQIQRQ", "length": 512, "header": "tr|A0A8V0YEJ6-1|A0A8V0YKX8_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10138540, "end_pos": 10128677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032497.1", "url": "https://www.ensembl.org/id/ENSGALT00010032497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019240.1", "url": "https://www.ensembl.org/id/ENSGALP00010019240.1" } ] } }, { "isoform_ac": "A0A8V0YK60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK60/entry", "sequence": { "sequence": "MCVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSSESLYWGMLLDVPFSACSVTTLTLGLSGP", "length": 369, "header": "tr|A0A8V0YK60-1|A0A8V0YKX8_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10131287, "end_pos": 10129766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032444.1", "url": "https://www.ensembl.org/id/ENSGALT00010032444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019198.1", "url": "https://www.ensembl.org/id/ENSGALP00010019198.1" } ] } }, { "isoform_ac": "A0A8V0YK91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK91/entry", "sequence": { "sequence": "PAATAQAVPSLLSSDPAVLLLSPHAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSSE", "length": 366, "header": "tr|A0A8V0YK91-1|A0A8V0YKX8_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10146819, "end_pos": 10129931, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032481.1", "url": "https://www.ensembl.org/id/ENSGALT00010032481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019228.1", "url": "https://www.ensembl.org/id/ENSGALP00010019228.1" } ] } }, { "isoform_ac": "A0A8V0YKV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV7/entry", "sequence": { "sequence": "MQAPSPELNPGLLQSVQYQILQKVEIERKKMCHRDGKLAARGDGACCELGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGKSSPSARLHEPEKSSGTTTTQESDPNNMTYADLNFAKEKRKSVRRVIELSQQSEYACIQGSNSSSSQPASSSDNLTYADLDMVHLSKAPRRPPPCPEESSSEYASVQIQRQ", "length": 532, "header": "tr|A0A8V0YKV7-1|A0A8V0YKV7_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10133519, "end_pos": 10128677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032468.1", "url": "https://www.ensembl.org/id/ENSGALT00010032468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019216.1", "url": "https://www.ensembl.org/id/ENSGALP00010019216.1" } ] } }, { "isoform_ac": "A0A8V0YKX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8/entry", "sequence": { "sequence": "MGYKDSSSNLRCSRVLSLLSLTPIGQTAHSTWSPQISHSCFCHGPSWLGCWRCVLSRMALNAHCIWEHCASPPPPCFPRSPHHNSTGLCAVPGGARGRQSSSSRRSPPCAGTAAAAPSLPASLRGGALPPAHLKKAAAGVPGGAPTHEFGRSQAVPGCGEPRRYRGRSRCQGNGGGAAEGRCGAERCGAERPRGRSGPGQEEPEMEPRPPAWPLLCLLLLCQSSCAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGKSSPSARLHEPEKSSGTTTTQESDPNNMTYADLNFAKEKRKSVRRVIELSQQSEYACIQGSNSSSSQPASSSDNLTYADLDMVHLSKAPRRPPPCPEESSSEYASVQIQRQ", "length": 709, "header": "tr|A0A8V0YKX8-1|A0A8V0YKX8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10136301, "end_pos": 10128677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032493.1", "url": "https://www.ensembl.org/id/ENSGALT00010032493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019237.1", "url": "https://www.ensembl.org/id/ENSGALP00010019237.1" } ] } }, { "isoform_ac": "A0A8V0YMS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS5/entry", "sequence": { "sequence": "MEPRPPAWPLLCLLLLCQSSCAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGKSSPSARLHEPEKSSGTTTTQESDPNNMTYADLNFAKEKRKSVRRVIELSQQSEYACIQGSNSSSSQPASSSDNLTYADLDMVHLSKAPRRPPPCPEESSSEYASVQIQRQ", "length": 505, "header": "tr|A0A8V0YMS5-1|A0A8V0YMS5_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10135491, "end_pos": 10128677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032489.1", "url": "https://www.ensembl.org/id/ENSGALT00010032489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019233.1", "url": "https://www.ensembl.org/id/ENSGALP00010019233.1" } ] } }, { "isoform_ac": "A0A8V0YSR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSR6/entry", "sequence": { "sequence": "MQWEEPEMEPRPPAWPLLCLLLLCQSSCAGVGAQTYPDFKLQQPQSSEVVIKGDTLTLNCTVSGSGPVGPVKWVKGWGSDNQTVYEHKGSFPRVMRAVPDPSNDFTIRISNVSLEDAGTYYCVKFRKGTVDDVVFTKGGGTEVSVHARPSVPVVSGPSHRAVPGQSVPFTCSAKEFSPRDIRVKWLKNSTLVRAEPPHVTPELSNSSYRMSSTLQVKLSEDDVRSELTCEVQHPTLAAPLRKTYALHQALRVPPSVSVVAAPSGAVEVNKTVNFTCRVQGFYPGAVNVSWLENGTEMNTGNSTQPTETSRGLFELNDTVTVQAGEEKSGFKFTCLVVHEDQEPISGTGILWVTPPALGESNEGLIGDSKSLIYVAVGVVCTVLALLVIAILYLIRTKQSKGYTSRRRAAGPPPRRSLTPTT", "length": 421, "header": "tr|A0A8V0YSR6-1|A0A8V0YKX8_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=TPPNR1L PE=4 SV=1 CANONICAL=A0A8V0YKX8-1" }, "locus": { "chromosome": "20", "start_pos": 10138540, "end_pos": 10128928, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032485.1", "url": "https://www.ensembl.org/id/ENSGALT00010032485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019231.1", "url": "https://www.ensembl.org/id/ENSGALP00010019231.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771734", "resource": "KEGG Pathway" }, { "id": "R-GGA-202733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-GGA-391160", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391160", "resource": "Reactome", "description": "Signal regulatory protein family interactions" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 319, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 660, "end_pos": 662 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJP9-1", "uniprot_ac": "A0A8V0YJP9", "uniprot_id": "A0A8V0YJP9_CHICK", "mass": { "chemical_mass": 63439.0, "monoisotopic_mass": 63439.0 }, "refseq": { "ac": "NP_001006581", "name": "serine/threonine-protein kinase RIO2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006581" }, "gene_names": [ { "name": "RIOK2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "name": "RIOK2", "type": "synonym", "evidence": [ { "id": "NP_001006581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006581" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase RIO2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9/entry#names_and_taxonomy" } ] }, { "name": "RIO kinase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine-protein kinase rio2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase RIO2", "type": "synonym", "evidence": [ { "id": "NP_001006581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006581" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01053636.1, AJ719586.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1. On Sep 23, 2021 this sequence version replaced NP_001006581.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001006581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006581" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIOK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9", "locus": { "chromosome": "Z", "start_pos": 52229975, "end_pos": 52217541, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011881", "url": "https://www.ensembl.org/id/ENSGALG00010011881" } ] } } ], "crossref": [ { "id": "A0A8V0YJP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05144", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05144", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427278", "url": "https://www.ncbi.nlm.nih.gov/gene/427278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427278", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACPHLIA", "url": "https://omabrowser.org/oma/group/ACPHLIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YEZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP9", "url": "https://www.orthodb.org/?gene=A0A8V0YJP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45852", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45852", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45852:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45852:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01163", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01163", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKLNVVMLRYLSKEHFRVLTAVEMGMKNHEIVPASLIASIASLKHGGCNKILRELGKHRLLAYERTKTVQGYRLTNAGYDYLALKTLSSRQVISSVGNQMGVGKESDIYIVANEDEQQFAMKLHRLGRTSFRSLKNKRDYHKHRHKMSWLYLSRLAAMKEFAYMKALYDRKFPVPKPVDYNRHAVIMELLDGYPLCQVRQMEDPASVYSELMDLIVKLANHGLIHGDFNEFNLILDNDDHVTMIDFPQMISTSHPNAEWYFDRDVNCIKEFFKKRFNYESELFPEFKDIRRESSLDIEIAASGYTKEMQEDDELLHPLRSDEDDHTAEVSESEEFAESNLKFFRSNQEDNVELIHEEDSESRTSEDATYNNEEADTTETSENLQKLSLTESSSALDKVEGQPVCCKSSEDGVSYVTLFPEHERMLEGTSKNKATQGDHCIDKDKEDDECPDLVDLSTLHKTLKPYRNEDNIPHIAENKARTRTTSVSSLGSCSTIPPELVKKKIKRQLTKQQKSALRQRLQKGEANIYTKQRRENMQNIKSSLDAASFWG", "length": 551, "header": "tr|A0A8V0YJP9-1|A0A8V0YJP9_CHICK Isoform 1 of Serine/threonine-protein kinase RIO2 OS=Gallus gallus OX=9031 GN=RIOK2 PE=3 SV=1 CANONICAL=A0A8V0YJP9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ6/entry", "sequence": { "sequence": "MHLPGSRQAGSLSRRRSALCACAGVAEACCCAGRGLSGCRHGEAERGHAAVPLQGALPSPNSAVQGYRLTNAGYDYLALKTLSSRQVISSVGNQMGVGKESDIYIVANEDEQQFAMKLHRLGRTSFRSLKNKRDYHKHRHKMSWLYLSRLAAMKEFAYMKALYDRKFPVPKPVDYNRHAVIMELLDGYPLCQVRQMEDPASVYSELMDLIVKLANHGLIHGDFNEFNLILDNDDHVTMIDFPQMISTSHPNAEWYFDRDVNCIKEFFKKRFNYESELFPEFKDIRRESSLDIEIAASGYTKEMQEDDELLHPLRSDEDDHTAEVSESEEFAESNLKFFRSNQEDNVELIHEEDSESRTSEDATYNNEEADTTETSENLQKLSLTESSSALDKVEGQPVCCKSSEDGVSYVTLFPEHERMLEGTSKNKATQGDHCIDKDKEDDECPDLVDLSTLHKTLKPYRNEDNIPHIAENKARTRTTSVSSLGSCSTIPPELVKKKIKRQLTKQQKSALRQRLQKGEANIYTKQRRENMQNIKSSLDAASFWG", "length": 545, "header": "tr|A0A8V0YEZ6-1|A0A8V0YJP9_CHICK Computationally mapped isoform of Serine/threonine-protein kinase RIO2 OS=Gallus gallus OX=9031 GN=RIOK2 PE=3 SV=1 CANONICAL=A0A8V0YJP9-1" }, "locus": { "chromosome": "Z", "start_pos": 52229418, "end_pos": 52217740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028395.1", "url": "https://www.ensembl.org/id/ENSGALT00010028395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016278.1", "url": "https://www.ensembl.org/id/ENSGALP00010016278.1" } ] } }, { "isoform_ac": "A0A8V0YJP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9/entry", "sequence": { "sequence": "MGKLNVVMLRYLSKEHFRVLTAVEMGMKNHEIVPASLIASIASLKHGGCNKILRELGKHRLLAYERTKTVQGYRLTNAGYDYLALKTLSSRQVISSVGNQMGVGKESDIYIVANEDEQQFAMKLHRLGRTSFRSLKNKRDYHKHRHKMSWLYLSRLAAMKEFAYMKALYDRKFPVPKPVDYNRHAVIMELLDGYPLCQVRQMEDPASVYSELMDLIVKLANHGLIHGDFNEFNLILDNDDHVTMIDFPQMISTSHPNAEWYFDRDVNCIKEFFKKRFNYESELFPEFKDIRRESSLDIEIAASGYTKEMQEDDELLHPLRSDEDDHTAEVSESEEFAESNLKFFRSNQEDNVELIHEEDSESRTSEDATYNNEEADTTETSENLQKLSLTESSSALDKVEGQPVCCKSSEDGVSYVTLFPEHERMLEGTSKNKATQGDHCIDKDKEDDECPDLVDLSTLHKTLKPYRNEDNIPHIAENKARTRTTSVSSLGSCSTIPPELVKKKIKRQLTKQQKSALRQRLQKGEANIYTKQRRENMQNIKSSLDAASFWG", "length": 551, "header": "tr|A0A8V0YJP9-1|A0A8V0YJP9_CHICK Isoform 1 of Serine/threonine-protein kinase RIO2 OS=Gallus gallus OX=9031 GN=RIOK2 PE=3 SV=1 CANONICAL=A0A8V0YJP9-1" }, "locus": { "chromosome": "Z", "start_pos": 52229418, "end_pos": 52217861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028393.1", "url": "https://www.ensembl.org/id/ENSGALT00010028393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016276.1", "url": "https://www.ensembl.org/id/ENSGALP00010016276.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427278", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MBN7-1", "protein_name": "Serine/threonine-protein kinase RIO2", "gene_name": "RIOK2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPCSLVASIASLKHGGCNKVLRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDYHKHRHNMSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELISGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDEDDHITMIDFPQMVSTSHPNAEWYFDRDVKCIRDFFMKRFNYESELFPTFSDIRREDSLDVEVSASGYTKEMQADDELLHPAGPEDKNTETEERSDFPFSDEEMSERARDCRSENEGGWNCAAESVDCCCRSFENLEQIKEESLSEDSADAHRFEMTEFSQALEEIEGQVVENSSVSEFSGENRRERDARQDGETGQGGILVGPEEDEDECPHLIALSSLSKEFRPFRDEENMEDTNRHRTRTLSVTSVGSVLSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANTFTKQRRENMQNIKSSLEAASFWGE", "length": 551 }, "evidence": [ { "id": "A0A8V0YJP9", "url": "https://omabrowser.org/oma/group/A0A8V0YJP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BVS4-1", "protein_name": "Serine/threonine-protein kinase RIO2", "gene_name": "RIOK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESDHITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEVSASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTRTLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNIKSSLEAASFWGE", "length": 552 }, "evidence": [ { "id": "A0A8V0YJP9", "url": "https://omabrowser.org/oma/group/A0A8V0YJP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQS5-1", "protein_name": "Serine/threonine-protein kinase RIO2", "gene_name": "Riok2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPCSLIASIASLKHGGCNKILRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEAGQQLALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVIMELINGYPLCQIHHVEDPASVYDEAMELIVKLGNHGLIHGDFNEFNLMLDKDDHITMIDFPQMVSTSHPNAEWYFDRDVKCIREFFMKRFSYESELYPTFSDIRKEDSLDVEVSASGYTKEMQADDELLHPVGPDDKITETEEDSDFTFSDEEMLEKAKVWRSELEKEADPADESGGSWCCSSTDSKQIKDGGLPEESAHVSSFEVTALSQAVEEMERQVLPHRSVTEFSEESRRTENDGQPGQRSPAGSEDCDDEPPHLIALSSVNREFRPFRDEESMSSVTRHRTRTLSVTSAGSALSCSTIPPELVKQKVKRQLTRQQKAAARRRLQKGEANVFTKQRRENMQNIKSSLEAASFWGD", "length": 547 }, "evidence": [ { "id": "A0A8V0YJP9", "url": "https://omabrowser.org/oma/group/A0A8V0YJP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "positive regulation of ribosomal small subunit export from nucleus", "id": "GO:2000208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", 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Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"MVSAKEPAIAMSSGLSIALLHCLCLATCLTGPPGQSKKEEKLWPENFTSILNSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMETLIQANVIFIFLQFFCKIQEYTMDVFFRQTWVDKRLKYDGPIEILRLNNLMVSKVWTPDTFFRNGKKSVAHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPEESSSLVQYDLLGHTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMERAKRKTVKSLLEFPVAPIQREKCTEETHTSTDANSNVRKRTNATVQSEADGGSRIDTRHSSIQPPSVAQGSSDVTPHSLSASSPNPFTRINASETLSSARATPPAPPSTPILTGFVSQHATVGSPSIQHLLGSRLEQIQTTTPHTLGASAKPSAVTPPVPPASHSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM", "length": 574, "header": "tr|A0A8V0YKW6-1|A0A8V0YKW6_CHICK Isoform 1 of Gamma-aminobutyric acid type A receptor subunit alpha4 OS=Gallus gallus OX=9031 GN=GABRA4 PE=3 SV=1 CANONICAL=A0A8V0YKW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF30/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YF34" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF34" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFB8-1", "uniprot_ac": "A0A8V0YFB8", "uniprot_id": "A0A8V0YFB8_CHICK", "mass": { "chemical_mass": 134234.0, "monoisotopic_mass": 134234.0 }, "refseq": { "ac": "NP_001026485", "name": "probable cation-transporting ATPase 13A4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" }, "gene_names": [ { "name": "ATP13A4", "type": "recommended", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] }, { "name": "ATP13A4", "type": "synonym", "evidence": [ { "id": "NP_001026485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" } ] } ], "protein_names": [ { "name": "Cation-transporting ATPase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8/entry#names_and_taxonomy" } ] }, { "name": "7.2.2.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8/entry#names_and_taxonomy" } ] }, { "name": "ATPase type 13A4", "type": "synonym", "evidence": [ { "id": "NP_001026485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" } ] }, { "name": "P5-ATPase", "type": "synonym", "evidence": [ { "id": "NP_001026485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" } ] }, { "name": "probable cation-transporting ATPase 13A4", "type": "synonym", "evidence": [ { "id": "NP_001026485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992527, SAMEA103992648 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Nov 17, 2021 this sequence version replaced NP_001026485.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP13A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8", "locus": { "chromosome": "9", "start_pos": 12795396, "end_pos": 12762017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013759", "url": "https://www.ensembl.org/id/ENSGALG00010013759" } ] } } ], "crossref": [ { "id": "A0A8V0YFB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFB8", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR047821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424901", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTWEMAV", "url": "https://omabrowser.org/oma/group/TTWEMAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFB8", "url": "https://www.orthodb.org/?gene=A0A8V0YFB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YLQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45630:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45630:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGENPAKSHYAQLNLGEENEMEIFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVVLLRTTDEFRIYSRKNVTWISVSGIIKSRLDYPSFAEEDSIFSKALMKPSLQVKSIQVQKIRYVWNIYAKQFQKVGALEDHHTCSAIHTKFGSGLTCSEQSLRRVICGPNTIDVPVIPIWKLLIKEVLNPFYVFQLFSVCLWFAEDYMEYAAAIIIMSLLSISLTVYDLRQQSVKLQRLVESHNSIMVTVCRNKEGFQELESHHLVPGDMVVLKEGKALLPCDAILISGQCIVNESMLTGESIPVTKTQLPQADNLKPWKMHCAEDYKKHVLFCGTEVIQTKGDDRGVVKAVVLQTGFNTAKGDLVRSILYPKPMNFRLYRDALRFLMCLIAFAAIGMIYTVCVFALNGEEAGEVVKKALDVITIAVPPALPAALTTGIIYTQRRLKKKGIFCISPQRINMCGQLNLICFDKTGTLTEDGLDLWGLLPSEGNCFQDVRRFPADHSLPWGPAFRAMVVCHSLIVLEGKIQGDPLDVKMFEATNWVIDDSSGHQIEGQRSTHATVIRPGPKANTASVEGITILHQFPFSSALQRMSVIAQETGGEKQVFTKGAPEMVATLCRAETVPSNFESKLLFYTAQGFRVIGLAYKSLQSGKQSTDLTREEVESDLTFLGLLIMENRLKRETKPVLEELSDAHIRSVMVTGDNIQTAVTVAKNAGMISPTNRVILVEANKIPGSFSASVTWKPLKENKTEDDGNLDSGSQTGRRIRLAAEPGQFHFAMSGKSYQVVAQYFSHLLPKLLLNATVFARMSPSQKSSLVEEFQKLDYFVGMCGDGANDCGALKVAHAGISLSEQEASVASPFTSRTPSIACVPELIREGRAALVTSFCMFKYMALYSTIQYLGVLLLYWQLNSFGNYQFLFQDLAITTVIGMTMSFTEAYPKLVPYRPPSQLVSPPLLLSVILNILFSLGMQILGFLMVQKQPWYSKTDIHSACLSVNNHVENSSSASSLGLHGVGGGDPTEVDNGYKSYENTTVWLLSTINCLIIALVFSKGKPFRQPIYTNYVFIMVLVGQLGVCLFLVFADIDDLYSKMDLVCTPTTWRISMVMMLAVTLAVSFLVEEAIIENRALWLWLKKTFQYHSKSHYKRLQRVLEQDSAWPPLNETFSLDAVTVSVEEDMGGHSNPTFDSNEDAL", "length": 1205, "header": "tr|A0A8V0YFB8-1|A0A8V0YFB8_CHICK Isoform 1 of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A4 PE=3 SV=1 CANONICAL=A0A8V0YFB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8/entry", "sequence": { "sequence": "MGENPAKSHYAQLNLGEENEMEIFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVVLLRTTDEFRIYSRKNVTWISVSGIIKSRLDYPSFAEEDSIFSKALMKPSLQVKSIQVQKIRYVWNIYAKQFQKVGALEDHHTCSAIHTKFGSGLTCSEQSLRRVICGPNTIDVPVIPIWKLLIKEVLNPFYVFQLFSVCLWFAEDYMEYAAAIIIMSLLSISLTVYDLRQQSVKLQRLVESHNSIMVTVCRNKEGFQELESHHLVPGDMVVLKEGKALLPCDAILISGQCIVNESMLTGESIPVTKTQLPQADNLKPWKMHCAEDYKKHVLFCGTEVIQTKGDDRGVVKAVVLQTGFNTAKGDLVRSILYPKPMNFRLYRDALRFLMCLIAFAAIGMIYTVCVFALNGEEAGEVVKKALDVITIAVPPALPAALTTGIIYTQRRLKKKGIFCISPQRINMCGQLNLICFDKTGTLTEDGLDLWGLLPSEGNCFQDVRRFPADHSLPWGPAFRAMVVCHSLIVLEGKIQGDPLDVKMFEATNWVIDDSSGHQIEGQRSTHATVIRPGPKANTASVEGITILHQFPFSSALQRMSVIAQETGGEKQVFTKGAPEMVATLCRAETVPSNFESKLLFYTAQGFRVIGLAYKSLQSGKQSTDLTREEVESDLTFLGLLIMENRLKRETKPVLEELSDAHIRSVMVTGDNIQTAVTVAKNAGMISPTNRVILVEANKIPGSFSASVTWKPLKENKTEDDGNLDSGSQTGRRIRLAAEPGQFHFAMSGKSYQVVAQYFSHLLPKLLLNATVFARMSPSQKSSLVEEFQKLDYFVGMCGDGANDCGALKVAHAGISLSEQEASVASPFTSRTPSIACVPELIREGRAALVTSFCMFKYMALYSTIQYLGVLLLYWQLNSFGNYQFLFQDLAITTVIGMTMSFTEAYPKLVPYRPPSQLVSPPLLLSVILNILFSLGMQILGFLMVQKQPWYSKTDIHSACLSVNNHVENSSSASSLGLHGVGGGDPTEVDNGYKSYENTTVWLLSTINCLIIALVFSKGKPFRQPIYTNYVFIMVLVGQLGVCLFLVFADIDDLYSKMDLVCTPTTWRISMVMMLAVTLAVSFLVEEAIIENRALWLWLKKTFQYHSKSHYKRLQRVLEQDSAWPPLNETFSLDAVTVSVEEDMGGHSNPTFDSNEDAL", "length": 1205, "header": "tr|A0A8V0YFB8-1|A0A8V0YFB8_CHICK Isoform 1 of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A4 PE=3 SV=1 CANONICAL=A0A8V0YFB8-1" }, "locus": { "chromosome": "9", "start_pos": 12794501, "end_pos": 12762093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033035.1", "url": "https://www.ensembl.org/id/ENSGALT00010033035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019531.1", "url": "https://www.ensembl.org/id/ENSGALP00010019531.1" } ] } }, { "isoform_ac": "A0A8V0YLQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ6/entry", "sequence": { "sequence": "MGENPAKSHYAQLNLGEENEMEIFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVVLLRTTDEFRIYSRKNVTWISVSGIIKSRLDYPSFAEEDSIFSKALMKPSLQVKSIQVQKIRYVWNIYAKQFQKVGALEDHHTCSAIHTKFGSGLTCSEQSLRRVICGPNTIDVPVIPIWKLLIKEVLNPFYVFQLFSVCLWFAEDYMEYAAAIIIMSLLSISLTVYDLRQQSVKLQRLVESHNSIMVTVCRNKEGFQELESHHLVPGDMVVLKEGKALLPCDAILISGQCIVNESMLTGESIPVTKTQLPQADNLKPWKMHCAEDYKKHVLFCGTEVIQTKGDDRGVVKAVVLQTGFNTAKGDLVRSILYPKPMNFRLYRDALRFLMCLIAFAAIGMIYTVCVFALNGEEAGEVVKKALDVITIAVPPALPAALTTGIIYTQRRLKKKGIFCISPQRINMCGQLNLICFDKVTGWESLANFQDVRRFPADHSLPWGPAFRAMVVCHSLIVLEGKIQGDPLDVKMFEATNWVIDDSSGHQIEGQRSTHATVIRPGPKANTASVEGITILHQFPFSSALQRMSVIAQETGGEKQVFTKGAPEMVATLCRAETVPSNFESKLLFYTAQGFRVIGLAYKSLQSGKQSTDLTREEVESDLTFLGLLIMENRLKRETKPVLEELSDAHIRSVMVTGDNIQTAVTVAKNAGMISPTNRVILVEANKIPGSFSASVTWKPLKENKTEDDGNLDSGSQTGRRIRLAAEPGQFHFAMSGKSYQVVAQYFSHLLPKLLLNATVFARMSPSQKSSLVEEFQKLDYFVGMCGDGANDCGALKVAHAGISLSEQEASVASPFTSRTPSIACVPELIREGRAALVTSFCMFKYMALYSTIQYLGVLLLYWQLNSFGNYQFLFQDLAITTVIGMTMSFTEAYPKLVPYRPPSQLVSPPLLLSVILNILFSLGMQILGFLMVQKQPWYSKTDIHSACLSVNNHVENSSSASSLGLHGVGGGDPTEVDNGYKSYENTTVWLLSTINCLIIALVFSKGKPFRQPIYTNYVFIMVLVGQLGVCLFLVFADIDDLYSKMDLVCTPTTWRISMVMMLAVTLAVSFLVEEAIIENRALWLWLKKTFQYHSKSHYKRLQRVLEQDSAWPPLNETFSLDAVTVSVEEDMGGHSNPTFDSNEDAL", "length": 1193, "header": "tr|A0A8V0YLQ6-1|A0A8V0YLQ6_CHICK Computationally mapped isoform of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A4 PE=3 SV=1 CANONICAL=A0A8V0YFB8-1" }, "locus": { "chromosome": "9", "start_pos": 12794501, "end_pos": 12762093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033051.1", "url": "https://www.ensembl.org/id/ENSGALT00010033051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019543.1", "url": "https://www.ensembl.org/id/ENSGALP00010019543.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 724, "start_aa": "Thr", "end_pos": 724, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424901", "resource": "KEGG Pathway" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N236-1", "protein_name": "Cation-transporting ATPase", "gene_name": "Atp13a4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDHLETGQHALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGILPLVFHWRPAWHVWANCVPCSLQDADIVLLKTTDEFKVYSWKKVMWISLSALSRTPGLTPDHPLITDEEYIINRAIRKPDLKVRYIKVQKIRYVWNNLEGRFQKIGSLEDWLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEITPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVTSIALTVYDLRQQSVKLHHLVESHNSIIVSVFERKAGAQDLESRLLVPGDLLILTGSRVQMPCDAILIDGSCVVDEGMLTGESIPVTKTPLSQMASSAPWKMQTEADPRRHILFCGTEVIQARAAGSGTVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDPWGVVPCDQNGFKTVHSFASGKALPQGLLCAAMASCHSLILLDGTIQGDPLDLKMFEATKWVMTISGDDFHIKGMLAHTTVVKPTGTVGQVPAEGLAILHQFPFSSALQRMTVIVQEVGGDRLAFMKGAPERVASFCQPDTVPSSFISELQTYTTQGFRVIALAYKKLESDCPTTALMREKVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSEGQKVILVEANEATGSSSASISWELVEEKKHIPFGNQDNYINITEEASDNGREGTYHFALSGKSFNVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPSIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNMNGANPKLVPFRPAGRLISPPLLLSVILNILLSLAMHIVGFILVQKQPWYLMELHSACTMRNESISAMNMSPSVPEKTRSNSTFASFENTTIWFLGTINCILVALVFSKGKPFRQPTYTNYVFVLVLILQMGVCLFILFADIPELHRRLDLLCTPVPWRVYILIMISSNFVVSLAVEETIIENRALWLAVKRCFGYQSKSQYRIWQRNLANDSSWPPLNQTSYSDIQGVSYSNPVFESNEEQL", "length": 1193 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M9L4-1", "protein_name": "Cation-transporting ATPase", "gene_name": "Atp13a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDHLGKSQHALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGMLPLVFYWRPAWRVWANCVPCSLQEADIVLLRTTDEFKIYSWKKVMWISLSALSSTSGLTPDHPLIADEEFIINRAIRKPDLKVRYIKVQKIRYVWNNLEGQFQKIGSLEDCLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEIIPIWKLLVKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVISIALTVYDLRQQSVKLHHLVESHNSITVSVYERKAGAQDLESRLLVPGDLLILTGSRVQMPCDAVLIDGSCVVDEGMLTGESIPVTKTPLSQTASSAPWKMQSEADPRRHILFCGTEVIQAKAAGSGTVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDLWGVVPCDQNGFQAVHSFASGEAVPWGPLCAAMATCHSLILLDGTIQGDPLDLKMFEATQWEMTVSGDDFHNKEMLAHTMVVKPPDTVGQVPAEGLAILHQFPFSSALQRMTVIVQETGGGRMAFMKGAPERVASFCQPDTVPTTFISELQVYTTQGFRVIALAYKKLETDCPTTTLMREKVESDLIFLGLLILENRLKEETRPVLEELISARIRTAMITGDNLQTAITVARKSGMVSEGQKVILVEANEATDSSSASITWKLVEEKKHGLFGSQDTYINIREEVPENGREGNYHFALSGKSFQVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGVSLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWKTNSLSNYQFLFQDLAITTLIGVTMNLNGANPKLVPFRPAGRLISPPLLLSVILNILLSLAMHIVGFILVQKQPWYSMDYHSVCPVRNESVSALSASPNVPEKTRSNSTFASFENTTIWFLGTINCIVVALVFSKGKPFRQPTYTNYIFVLVLILQMGVCLFILFADIPELHRRLDLLCTPVLWRVYILIMVSSNFVVSLAVEKAIIENRALWTAVKRCFGYHSKSQYRVWQRNLATDSSWPPLNQTSYSDMQGVSYSNPVFESNEEQL", "length": 1193 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N272-1", "protein_name": "Cation-transporting ATPase", "gene_name": "ATP13A4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDHFEKGQHALLNEGEENEMEIFGYRTQSCRETLCLAGSIFSFGILPLVFYWKPAWHVWANCIPCSLQEADVVLLRTTDEFQTYSRKKVMWICLSALNSAFRLNPDNPFITDEESIINRAIRKPDLKVRCIKVQKIRYVWDNLEGQFRKIGCLEDWLSSAKIHLKFGSGLTTEEQEIRRLICGPNTIDVEITPIWKLLIKEVLNPFYVFQLFSVCLWFSEDYKEYAFAIIIMSIISIALTVYDLREQSVKLHRLVEAHNNITVSIYGKNAGVQELESRFLVPGDLLILMGNKVQMPCDAILIDGSCVVNEGMLTGESIPVTKTPLPKVDGSVPWKTQSEGEYKRHVLFCGTEVIQAKGACSSPVKAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGETPGEVVKKALDVITIAVPPALPAALTTGIMYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVPCDGNGFQEVHSFTSGRTLPWGPLYAAMTSCHSLILLDGTIQGDPLDLKMFEATTWEMVVSRDDFQLKGVPGCAMVVKPCGTSSQVPVEGIAILHQFPFSSVLQRMTVIVQEMGGDQLVFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIGLAYKKLEMDHHISALMRDQVESDLIFLGLLILENRLKEETKSVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWKLLEEKKHIACRNQDSYINIREEISDNSKEGSYHFALNGKSFQVISQHFSSLLPKILMNGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGVSLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNNLSNYQFLFQDLAITTIIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVILNILLSLAMHIVGFILVQRQPWYSLGIHSACTVQNDTISKLTVSPTAPVKNGTNGVFTSFENTTIWFLGTINCIIVALVFSKGKPFRQPTYKNYIFVLVLVVQLSVCLFILFADIPELYRCLDLLCTPVLWRVYIVIMLSSNFIVSLVVEEAIIENRALWMIIKRCFGYQSKSQYRILQRALANDPSWPPINQTSDSDMPECGRGVSYSNPVFESNEDQL", "length": 1197 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4VNC1-1", "protein_name": "Probable cation-transporting ATPase 13A4", "gene_name": "ATP13A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHFEKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMESNSTFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRALWMMIKRCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEEQL", "length": 1196 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54X63-1", "protein_name": "Cation-transporting ATPase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKETKIDKFEKSKYNKRYNEPNDPLEIDYMRGYQTTTLSNILHYGLIILSAGLLLLVYHWVPRWGIKMRFKECKLNDANYVYVKAKDKKYELSQVKHVLIGKKDLEFSESEKKDKYIEFKFTRLFYNVEKDLFIRPISNTDYHRSKINELVKTGLSMNKYQEGRDLFGPNLISVPLKSIPSLLLDEILHPFFIFQIYSIILWCTEDYYVYAGAILFIALVTAIFTLRETRNNLLRLNEIATYRCDVTVLRDGKLQVVSSETLVPGDIIEIQKSLVLPCDFCLLTGTVILNESMLTGESIPVTKYSLEECSGDQLSVDPLVNKRCAMSGGTKVVKTQAKEKDAKIFAMVTNTSWLTTKGGLVLSMLYPKESHFKFFEQSLKFLGVLCFIALIGFGVSVWRLIKAGEQLSEVVTKALDLITIVVPPALPMAQSVGTGFSIVRLKANKIFCISPPRVNMAGKVEVYCFDKTGTLTEDGLDLFGVLPSHQDSNNSGGFGTVIKTDLNRMTGPLFLTMATCHTLAHIDEQVSGDPLEEKIFTATNAKLNDNGEFGFCASIQLSKVDNISMVHQEYPISTVDVETSDQIALVERFEFQSALQRMSVVIRGIRATDGSTQSSKDLAIVKGSPEMIKKLSNPTSIPSDFEHVLSTYTKKGYRVLGCGYKEWDPSDSIGKTKDEIRSMVERDLMFLGFIIMENKIKPETAGALKVLKDANIRIIMVTGDNVLTAVSVSRECGLVTKEKTIFSSQLVNDPVTGKPTMVEWFDVTSPEESIPFTLDPYTLTINNAGGGSNYDDEYSLAVTGDVWKYYYDQFKANGQPTICFNQILRKGQVFARMTPDQKQNLIEELQVLGLYVGMCGDGANDCGALKAAHVGISLSQAEASIAAPFTSTITNVTCTYNLIKEGRASLTVSFKLFQFIGMYSLIQFCQVILLYFDGSVLNNYQYLYQDLWVIFPLVIFMGRTEPCSKLSIKRPSSRLISSTVIGSLLSHVTLTFVFQLLVYIFVRRNSWYKDLPDTSSNENEPRLDHLLASLFIYGNMQYSVMCFIYSWGKPFLRPIYTNRALFIFFCVTLTTSSLLLLLPVSIRFFGTTWLMDLPVRWRVELLILFIINAALAMAAEWIIIVYREIRSKSKRKLKQKQNSDPNIIAKNTVNERYTSLN", "length": 1158 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XF90-1", "protein_name": "Probable cation-transporting ATPase 13A4", "gene_name": "Atp13a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDHLEKSQHALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGMLPLVFYWRPAWRVWANCVPCSLQEADVVLLKTTDEFKIYSWKKVIWISLSALSSTSGLTPDHPLITDEGYIINRAIRKPDLKVRYIKVQKIRYVWNNLEGQFQKIGSLEDWLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEITPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVISIALTVYDLRQQSVKLHHLVESHNSITVSVYERKAGAQDLESRLLVPGDLLILTGSRVQMPCDAILIDGSCVVDEGMLTGESIPVTKTPLSQTASSVPWKMQSEADPRRHVLFCGTEVIQAKAAGSGAVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMVYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDPWGVVPCDQNGFQAVHSFASGKALPQGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATKWEMTASGDDLHIKEMLAHTIVVKPTDMVGQVPAEGLAIVHQFPFSSALQRMTVIVQEMGGGRLAFMKGAPERVASFCQPDTVPTSFISELQIYTTQGFRVIALAYKKLEMDCPTTALMREKVESDLVFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSEGQKVILVEANEATGSSSASISWKLVEEKKPGPFGSQDTYINIREEVPENGRDRSYHFALSGKSFHVISQYFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWKTNSLSNYQFLFQDLAITTLIGVTMNLNGANPKLVPFRPAGRLISPPLLLSVVLNILLSLAMHIVGFILVQKQPWYIMDYHSVCPVRNESASALAASPSVPEKTRSNSTFASFENTTIWFLGTINCIFVALVFSKGKPFRQPTYTNYIFVLVLILQMGVCLFILFADIPEMHRRLDLLCTPVLWRVYILIMISSNFVVSLAVEKAIIENRALWIAVKRCFGYQSKSQYRIWQRNLANDSSWPPLNQTSYSDMQGVSYSNPVFESNEEQL", "length": 1193 }, "evidence": [ { "id": "A0A8V0YFB8", "url": "https://omabrowser.org/oma/group/A0A8V0YFB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "ATPase-coupled monoatomic cation transmembrane transporter activity", "id": "GO:0019829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "P-type ion transporter activity", "id": "GO:0015662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015662", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "polyamine transmembrane transporter activity", "id": "GO:0015203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" }, { "name": "polyamine transmembrane transport", "id": "GO:1902047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1174, "end_pos": 1176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-GGA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-5252122" ], "output_participant_list": [ "R-ALL-5252016" ], "enzyme_list": [ "A0A8V0YFB8-1", "A0A8V0YFG2-1" ], "evidence": [ { "id": "R-GGA-5251989", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5251989" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5252016", "participant_name": "divalent metal cation [cytosol]", "crossref": [ { "id": "60240", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5252122", "participant_name": "divalent metal cation [extracellular region]", "crossref": [ { "id": "60240", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": 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"evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": 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"activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": 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"activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": 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"id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] } ] }, { "uniprot_ac": "O12944", "gene_name": "RAD54L", "activity": [ { 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVARRFPLTRPDLCKKWEAAVKRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFCYTEPSEKPEEFSEQPEDPLPPPPPPPPPPPPPPPPPPAAPMLPPSPSAPSFHLSQIDARFVDPSIGLLMPPLQTPSNLAVFCDHNYTVEDTVHQRKRIQQLEEQVEKLRKKLKTAQQRCRRQERQIEKLREIVQFQKEKDILAGKGYVILPNDYFEVVEVPA", "length": 225, "header": "tr|A0A8V0YFC0-1|A0A8V0YFC0_CHICK Isoform 1 of THAP domain-containing protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YFC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0/entry", "sequence": { "sequence": "MVARRFPLTRPDLCKKWEAAVKRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFCYTEPSEKPEEFSEQPEDPLPPPPPPPPPPPPPPPPPPAAPMLPPSPSAPSFHLSQIDARFVDPSIGLLMPPLQTPSNLAVFCDHNYTVEDTVHQRKRIQQLEEQVEKLRKKLKTAQQRCRRQERQIEKLREIVQFQKEKDILAGKGYVILPNDYFEVVEVPA", "length": 225, "header": "tr|A0A8V0YFC0-1|A0A8V0YFC0_CHICK Isoform 1 of THAP domain-containing protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YFC0-1" }, "locus": { "chromosome": "Z", "start_pos": 54332219, "end_pos": 54328210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028592.1", "url": "https://www.ensembl.org/id/ENSGALT00010028592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016421.1", "url": "https://www.ensembl.org/id/ENSGALP00010016421.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { 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"total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" }, { "name": "endothelial cell proliferation", "id": "GO:0001935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC0" }, { "id": "PS50950", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50950" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THAP-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 62, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"evidence": [ { "id": "A0A8V0YFE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1/entry#names_and_taxonomy" } ] }, { "name": "phosphoglycerate kinase 1", "type": "synonym", "evidence": [ { "id": "NP_990316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316" } ] }, { "name": "phosphoglycerate kinase", "type": "synonym", "evidence": [ { "id": "NP_990316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01155910.1, HAEK01090319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_990316.2.", "evidence": [ { "database": "RefSeq", "id": "NP_990316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316" } ] }, { "annotation": "Single nucleotide polymorphism of this enzyme is an adaptation to the external anoxic environment.", "evidence": [ { "database": "RefSeq", "id": "NP_990316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316" }, { "database": "PubMed", "id": "17609890", "url": "https://glygen.org/publication/PubMed/17609890" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1", "locus": { 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"https://www.reactome.org/PathwayBrowser/#R-GGA-70263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14801", "url": "https://www.rhea-db.org/rhea/14801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDHKITNNQRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSSV", "length": 417, "header": "tr|A0A8V0YFE1-1|A0A8V0YFE1_CHICK Isoform 1 of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC7/entry", "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDHKITNNQRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGNCSFVLTCLSKLGSSGYSALC", "length": 426, "header": "tr|A0A8V0YFC7-1|A0A8V0YFE1_CHICK Computationally mapped isoform of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "locus": { "chromosome": "4", "start_pos": 12906250, "end_pos": 12897123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033050.1", "url": "https://www.ensembl.org/id/ENSGALT00010033050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019541.1", "url": "https://www.ensembl.org/id/ENSGALP00010019541.1" } ] } }, { "isoform_ac": "A0A8V0YFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD6/entry", "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDHKITNNQRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGKVLPGVDALSSV", "length": 378, "header": "tr|A0A8V0YFD6-1|A0A8V0YFD6_CHICK Computationally mapped isoform of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "locus": { "chromosome": "4", "start_pos": 12907862, "end_pos": 12897123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033065.1", "url": "https://www.ensembl.org/id/ENSGALT00010033065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019551.1", "url": "https://www.ensembl.org/id/ENSGALP00010019551.1" } ] } }, { "isoform_ac": "A0A8V0YFE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1/entry", "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDHKITNNQRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSSV", "length": 417, "header": "tr|A0A8V0YFE1-1|A0A8V0YFE1_CHICK Isoform 1 of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "locus": { "chromosome": "4", "start_pos": 12907862, "end_pos": 12897123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033074.1", "url": "https://www.ensembl.org/id/ENSGALT00010033074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019556.1", "url": "https://www.ensembl.org/id/ENSGALP00010019556.1" } ] } }, { "isoform_ac": "A0A8V0YLQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ1/entry", "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDHKITNNQRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGIGILSNFG", "length": 413, "header": "tr|A0A8V0YLQ1-1|A0A8V0YLQ1_CHICK Computationally mapped isoform of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "locus": { "chromosome": "4", "start_pos": 12906546, "end_pos": 12897123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033045.1", "url": "https://www.ensembl.org/id/ENSGALT00010033045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019538.1", "url": "https://www.ensembl.org/id/ENSGALP00010019538.1" } ] } }, { "isoform_ac": "A0A8V0YTJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTJ7/entry", "sequence": { "sequence": "MSLSNKLTLDKVDVKGKRVVMRIKAAVPTIKHCLDHGAKSVVLMSHLGRPDGVPMPDKFSLAPVAVELKALLGREVSFLKDCVGPEVEKACANPADGSVILLENLRFHVEEEGKGKDASGNKIKADAAKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVHLPQKAAGFLMKKELDYFAKALESPERPFLAILGGAKVQDKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMQIGNSLFDEEGSKIVKDLMAKAEKNGVKITLPVDFITADKFDEHAQTGEATVASGIPAGWMGLDCGPESVKKFVEVVGRAKQIVWNGPVGVFEWDKFSKGTKALMDKVVEVTGKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSSV", "length": 400, "header": "tr|A0A8V0YTJ7-1|A0A8V0YFE1_CHICK Computationally mapped isoform of Phosphoglycerate kinase OS=Gallus gallus OX=9031 GN=PGK2 PE=1 SV=1 CANONICAL=A0A8V0YFE1-1" }, "locus": { "chromosome": "4", "start_pos": 12907862, "end_pos": 12897123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033055.1", "url": "https://www.ensembl.org/id/ENSGALT00010033055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019547.1", "url": "https://www.ensembl.org/id/ENSGALP00010019547.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Differential gene expression of phosphoglyceric kinase (PGK) and hypoxic adaptation in chicken.", "journal": "Science in China. Series C, Life sciences", "date": "2007-06", "authors": "Wang CunFang, Yuan CunZhong, Zhang Lao, Wu ChangXin, Li Ning", "evidence": [ { "database": "RefSeq", "id": "NP_990316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990316" } ], "reference": [ { "type": "PubMed", "id": "17609890", "url": "https://glygen.org/publication/PubMed/17609890" } ] } ], "pathway": [ { "id": "gga:395833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395833", "resource": "KEGG Pathway" }, { "id": "R-GGA-70171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70171", "resource": "Reactome", "description": "Glycolysis" }, { "id": "R-GGA-70263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70263", "resource": "Reactome", "description": "Gluconeogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RPH0-1", "protein_name": "Phosphoglycerate kinase", "gene_name": "PGK1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAIPSIKFCLDNGAKSVVLMSHLGRPDGIPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEEEGKGKDASGSKVKADPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPKKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGSKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKIGQATVASGIPAGWMGLDCGPESSKKYSEAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV", "length": 417 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00558-1", "protein_name": "Phosphoglycerate kinase 1", "gene_name": "PGK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI", "length": 417 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P00560-1", "protein_name": "Phosphoglycerate kinase", "gene_name": "PGK1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK", "length": 416 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P09411-1", "protein_name": "Phosphoglycerate kinase 1", "gene_name": "Pgk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV", "length": 417 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P16617-1", "protein_name": "Phosphoglycerate kinase 1", "gene_name": "Pgk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEVENACANPAAGTVILLENLRFHVEEEGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMAKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV", "length": 417 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01604-1", "protein_name": "Phosphoglycerate kinase", "gene_name": "Pgk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAFNKLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDGNKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKIVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIARAKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTGGGASLELLEGKTLPGVAALTSA", "length": 415 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3T0P6-1", "protein_name": "Phosphoglycerate kinase 1", "gene_name": "PGK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKYCLDSGAKSVVLMSHLGRPDGVPMPDKYSLQPVAVELKSLLGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPTKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPKKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLISNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGSKIVKDLMSKADKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSSV", "length": 417 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9GPM4-1", "protein_name": "Phosphoglycerate kinase", "gene_name": "pgkA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNKIGNKLSLDKVDVKGKRVLIRVDYNVPLDKNNNITSTQRIDASIPTLEYCLKNGAKSIVLMSHLGRPDGLVKPEYSLKPVVKVLEDQLKRPIKFLSDCVGEQVEKECANPEEGTVILLENLRFHIEEEGSGVDAEGKKVKANPEKVKEFRESLTKLGDVYVNDAFGTAHRAHSSMVGINLPQKAAGFLMKKELEYFAKALESPSKPFLAILGGAKVSDKIKLIENLLYKVDEMIIGGGMAFTFKKFIDNKEIGSSLFEKTAEQITKDIIAKAAKNNVKLHFPVDYVIADKFDNDANIKTVTQDQGIPEGWMGLDCGPETIKENRDTISRAKTIVWNGPMGVFEKSNFEAGTKAAMDDVVNATTNGAITIIGGGDTATCAAKYNTEDKVSHVSTGGGASLELLEGKELPGVTALSDL", "length": 420 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SAJ4-1", "protein_name": "Phosphoglycerate kinase 3, cytosolic", "gene_name": "PGK3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATKRSVGTLKEADLKGKSVFVRVDLNVPLDDNSNITDDTRIRAAVPTIKYLMGNGSRVVLCSHLGRPKGVTPKYSLKPLVPRLSELLGVEVVMANDSIGEEVQKLVAGLPEGGVLLLENVRFYAEEEKNDPEFAKKLAALADVYVNDAFGTAHRAHASTEGVAKFLKPSVAGFLMQKELDYLVGAVANPKKPFAAIVGGSKVSTKIGVIESLLNTVDILLLGGGMIFTFYKAQGLSVGSSLVEEDKLDLAKSLMEKAKAKGVSLLLPTDVVIADKFAPDANSKIVPATAIPDGWMGLDIGPDSIKTFSEALDTTKTIIWNGPMGVFEFDKFAAGTEAVAKQLAELSGKGVTTIIGGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKPLPGVLALDEA", "length": 401 }, "evidence": [ { "id": "A0A8V0YFE1", "url": "https://omabrowser.org/oma/group/A0A8V0YFE1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphoglycerate kinase activity", "id": "GO:0004618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004618", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14801", "name": "", "equation": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFE1-1", "P51903-1" ], "evidence": [ { "id": "14801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14801" } ] }, { "id": "R-GGA-70486", "name": "PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFE1-1" ], "evidence": [ { "id": "R-GGA-70486", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70486" } ] }, { "id": "R-GGA-71850", "name": "PGK complexes dephosphorylate 1,3BPG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YFE1-1" ], "evidence": [ { "id": "R-GGA-71850", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71850" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YFE1", "gene_name": "PGK2", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "A0A8V0YFE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YFE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE1" } ] } ] }, { "uniprot_ac": "P51903", "gene_name": "PGK", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P51903", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51903" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "P51903", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51903" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.2.3", "ec_name": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "2.7.2.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3" }, { "id": "2.7.2.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.2.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFC9-1", "uniprot_ac": "A0A8V0YFC9", "uniprot_id": "A0A8V0YFC9_CHICK", "mass": { "chemical_mass": 18118.0, "monoisotopic_mass": 18118.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Transcription factor JunB", "type": "recommended", "evidence": [ { "id": "A0A8V0YFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor AP-1 subunit JunB", "type": "synonym", "evidence": [ { "id": "A0A8V0YFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14696", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14696", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFC9", "url": "https://www.orthodb.org/?gene=A0A8V0YFC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11462:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11462:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRRAKRQSTAEHRISERGPSPSPAQPLRAGGRRRGARGRRRRRWGGQTAGPGRGVGPVAPGGGSVPAESRGLRAPAEQSRAAPYRGSAPTPPSLSPLDAESQERLKAERKRLRNRIAASKCRRRKLERIARLEEKVKALKGQNAELIWGGLAIKWQLYCMLFE", "length": 164, "header": "tr|A0A8V0YFC9-1|A0A8V0YFC9_CHICK Isoform 1 of Transcription factor JunB OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YFC9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9/entry", "sequence": { "sequence": "MDRRAKRQSTAEHRISERGPSPSPAQPLRAGGRRRGARGRRRRRWGGQTAGPGRGVGPVAPGGGSVPAESRGLRAPAEQSRAAPYRGSAPTPPSLSPLDAESQERLKAERKRLRNRIAASKCRRRKLERIARLEEKVKALKGQNAELIWGGLAIKWQLYCMLFE", "length": 164, "header": "tr|A0A8V0YFC9-1|A0A8V0YFC9_CHICK Isoform 1 of Transcription factor JunB OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YFC9-1" }, "locus": { "chromosome": "Z", "start_pos": 54335403, "end_pos": 54332916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028608.1", "url": "https://www.ensembl.org/id/ENSGALT00010028608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016431.1", "url": "https://www.ensembl.org/id/ENSGALP00010016431.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC9" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 147, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 91 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFG2-1", "uniprot_ac": "A0A8V0YFG2", "uniprot_id": "A0A8V0YFG2_CHICK", "mass": { "chemical_mass": 133275.0, "monoisotopic_mass": 133275.0 }, "refseq": { "ac": "XP_040535722", "name": "probable cation-transporting ATPase 13A5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535722" }, "gene_names": [ { "name": "ATP13A5", "type": "recommended", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] }, { "name": "ATP13A5", "type": "synonym", "evidence": [ { "id": "XP_040535722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535722" } ] } ], "protein_names": [ { "name": "Cation-transporting ATPase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2/entry#names_and_taxonomy" } ] }, { "name": "7.2.2.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2/entry#names_and_taxonomy" } ] }, { "name": "probable cation-transporting ATPase 13A5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040535722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535722" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052581.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040535722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP13A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2", "locus": { "chromosome": "9", "start_pos": 12827274, "end_pos": 12800166, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013786", "url": "https://www.ensembl.org/id/ENSGALG00010013786" } ] } } ], "crossref": [ { "id": "A0A8V0YFG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07542", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07542", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424902", "url": "https://www.ncbi.nlm.nih.gov/gene/424902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMEDCNV", "url": "https://omabrowser.org/oma/group/KMEDCNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFG2", "url": "https://www.orthodb.org/?gene=A0A8V0YFG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFH2", "url": "https://www.orthodb.org/?gene=A0A8V0YFH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTN3", "url": "https://www.orthodb.org/?gene=A0A8V0YTN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45630:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45630:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040535722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535722", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKIWKDHYALLNKDEENELEAFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVILLRTTDEFQKYTRKKVTWIDLSTLTLPTGSNSEYPLVADKDSVINRAIMKPQLKMRCIQVQKIRYIWDFSVKEFRKVGSLEDSNTCHSIHHKFGAGLTGEERKIRQLVCGPNAIEVEIRPIWRLLFKEILNPFYVFQAFTLTLWLSQGYIEYSVAIIVLSVISVGLTVYDLRQQSTKLHDLVEEHNKVQVTVCTKNEGFKELESHYLVPGDVFLLDGKKLSLPCDAVLIDGSCIVNEGMLTGESIPVMKTLLPFTESPEPWKTHSMEDYRRHVLFCGTEVIQAKSSGRGPARAVVLQTGFNTAKGDLVRSILYPRPLNFQLYRDAFKFIVGLSAIGVLGLIYTVCVFTYHKKPVADVVAMALLLLTAAVPPAIPAALTTGTVYAQRRLKKKKIFCITPQRINICGQINLVCFDKTGTLTEDGLDLWGILPSEGSRFQKIHKFPSSTPLPWGPVCGAMASCHSLVVLDKKIQGDPLDLKMFEGTHWEIEESSTARDRAGATDVCIVRPGPNASSAPVEGIAILHQFPFSSGLQRMSVVSQKIGEEQYDLYMKGAPETVSSFCRQETVPSDFLEELKTYTSQGFRVIALAHKVLSLPEDVDVSDLEREEAESGLEFLGLLVMENRLKPETKPVLRELAAARIRSIMVTGDNLQTAVTVARNADMIHEASKVIIVEASEPEGSTPASIAWRLAEGSKASAAAPTEMCANTQEKITLGGESSNYHFAMNGKSYQVLIKHFYSLLPKILLNATVFARMSPGQKSSLVEELQKLDYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSQIPNIQCVPELIREGRAALVASFAVVKYLTLYGLIQFVGTALLFWQLQIFGNYQYLIQDMVITLLVCLTMSLTEAYPKLAPYRPPGQLISPPLLLSVILNVCFTIAMQTCGFLLVKKQPWYVALASWRHCSLGNQTLPPASPGENSTSSSDHSTVLSYEGTTLWPLSSVNCIIVAFVFSKGKPFRKPIYTNYVFSALLTLQLATCLFLFLADMDAVYSGMQFLCTPVIWRVYVLLMLLVTFCVSFFTEDVLLQNKHLWMLIKACVGYQSKSQYRKWQRMLQRDPNWPPVNTKDFAARSTAEVYINPSYEHRD", "length": 1193, "header": "tr|A0A8V0YFG2-1|A0A8V0YFG2_CHICK Isoform 1 of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A5 PE=3 SV=1 CANONICAL=A0A8V0YFG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2/entry", "sequence": { "sequence": "MEEKIWKDHYALLNKDEENELEAFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVILLRTTDEFQKYTRKKVTWIDLSTLTLPTGSNSEYPLVADKDSVINRAIMKPQLKMRCIQVQKIRYIWDFSVKEFRKVGSLEDSNTCHSIHHKFGAGLTGEERKIRQLVCGPNAIEVEIRPIWRLLFKEILNPFYVFQAFTLTLWLSQGYIEYSVAIIVLSVISVGLTVYDLRQQSTKLHDLVEEHNKVQVTVCTKNEGFKELESHYLVPGDVFLLDGKKLSLPCDAVLIDGSCIVNEGMLTGESIPVMKTLLPFTESPEPWKTHSMEDYRRHVLFCGTEVIQAKSSGRGPARAVVLQTGFNTAKGDLVRSILYPRPLNFQLYRDAFKFIVGLSAIGVLGLIYTVCVFTYHKKPVADVVAMALLLLTAAVPPAIPAALTTGTVYAQRRLKKKKIFCITPQRINICGQINLVCFDKTGTLTEDGLDLWGILPSEGSRFQKIHKFPSSTPLPWGPVCGAMASCHSLVVLDKKIQGDPLDLKMFEGTHWEIEESSTARDRAGATDVCIVRPGPNASSAPVEGIAILHQFPFSSGLQRMSVVSQKIGEEQYDLYMKGAPETVSSFCRQETVPSDFLEELKTYTSQGFRVIALAHKVLSLPEDVDVSDLEREEAESGLEFLGLLVMENRLKPETKPVLRELAAARIRSIMVTGDNLQTAVTVARNADMIHEASKVIIVEASEPEGSTPASIAWRLAEGSKASAAAPTEMCANTQEKITLGGESSNYHFAMNGKSYQVLIKHFYSLLPKILLNATVFARMSPGQKSSLVEELQKLDYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSQIPNIQCVPELIREGRAALVASFAVVKYLTLYGLIQFVGTALLFWQLQIFGNYQYLIQDMVITLLVCLTMSLTEAYPKLAPYRPPGQLISPPLLLSVILNVCFTIAMQTCGFLLVKKQPWYVALASWRHCSLGNQTLPPASPGENSTSSSDHSTVLSYEGTTLWPLSSVNCIIVAFVFSKGKPFRKPIYTNYVFSALLTLQLATCLFLFLADMDAVYSGMQFLCTPVIWRVYVLLMLLVTFCVSFFTEDVLLQNKHLWMLIKACVGYQSKSQYRKWQRMLQRDPNWPPVNTKDFAARSTAEVYINPSYEHRD", "length": 1193, "header": "tr|A0A8V0YFG2-1|A0A8V0YFG2_CHICK Isoform 1 of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A5 PE=3 SV=1 CANONICAL=A0A8V0YFG2-1" }, "locus": { "chromosome": "9", "start_pos": 12826849, "end_pos": 12800306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033113.1", "url": "https://www.ensembl.org/id/ENSGALT00010033113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019576.1", "url": "https://www.ensembl.org/id/ENSGALP00010019576.1" } ] } }, { "isoform_ac": "A0A8V0YFH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH2/entry", "sequence": { "sequence": "MEEKIWKDHYALLNKDEENELEAFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVILLRTTMRCIQVQKIRYIWDFSVKEFRKVGSLEDSNTCHSIHHKFGAGLTGEERKIRQLVCGPNAIEVEIRPIWRLLFKEILNPFYVFQAFTLTLWLSQGYIEYSVAIIVLSVISVGLTVYDLRQSTKLHDLVEEHNKVQVTVCTKNEGFKELESHYLVPGDVFLLDGKKLSLPCDAVLIDGSCIVNEGMLTGESIPVMKTLLPFTESPEPWKTHSMEDYRRHVLFCGTEVIQAKSSGRGPARAVVLQTGFNTAKGDLVRSILYPRPLNFQLYRDAFKFIVGLSAIGVLGLIYTVCVFTYHKKPVADVVAMALLLLTAAVPPAIPAALTTGTVYAQRRLKKKKIFCITPQRINICGQINLVCFDKTGTLTEDGLDLWGILPSEGSRFQKIHKFPSSTPLPWGPVCGAMASCHSLVVLDKKIQGDPLDLKMFEGTHWEIEESSTARDRAGATDVCIVRPGPNASSAPVEGIAILHQFPFSSGLQRMSVVSQKIGEEQYDLYMKGAPETVSSFCRQETVPSDFLEELKTYTSQGFRVIALAHKVLSLPEDVDVSDLEREEAESGLEFLGLLVMENRLKPETKPVLRELAAARIRSIMVTGDNLQTAVTVARNADMIHEASKVIIVEASEPEGSTPASIAWRLAEGSKASAAAPTEMCANTQEKITLGGESSNYHFAMNGKSYQVLIKHFYSLLPKILLNATVFARMSPGQKSSLVEELQKLDYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSQIPNIQCVPELIREGRAALVASFAVVKYLTLYGLIQFVGTALLFWQLQIFGNYQYLIQDMVITLLVCLTMSLTEAYPKLAPYRPPGQLISPPLLLSVILNVCFTIAMQTCGFLLVKKQPWYVALASWRHCSLGNQTLPPASPGENSTSSSDHSTVLSYEGTTLWPLSSVNCIIVAFVFSKGKPFRKPIYTNYVFSALLTLQLATCLFLFLADMDAVYSGMQFLCTPVIWRVYVLLMLLVTFCVSFFTEDVLLQNKHLWMLIKACVGYQSKSQYRKWQRMLQRDPNWPPVNTKDFAARSTAEVYINPSYEHRD", "length": 1143, "header": "tr|A0A8V0YFH2-1|A0A8V0YFH2_CHICK Computationally mapped isoform of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A5 PE=3 SV=1 CANONICAL=A0A8V0YFG2-1" }, "locus": { "chromosome": "9", "start_pos": 12826849, "end_pos": 12800306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033131.1", "url": "https://www.ensembl.org/id/ENSGALT00010033131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019586.1", "url": "https://www.ensembl.org/id/ENSGALP00010019586.1" } ] } }, { "isoform_ac": "A0A8V0YTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN3/entry", "sequence": { "sequence": "MEEKIWKDHYALLNKDEENELEAFGYKTQCCRKALCIAGYILSCGALLLLFYWKPEWDVWANCVPCSLEEADVILLRTTDEFQKYTRKKVTWIDLSTLTLPTGSNSEYPLVADKDSVINRAIMKPQLKMRCIQVQKIRYIWDFSVKEFRKVGSLEDSNTCHSIHHKFGAGLTGEERKIRQLVCGPNAIEVEIRPIWRLLFKEQSTKLHDLVEEHNKVQVTVCTKNEGFKELESHYLVPGDVFLLDGKKLSLPCDAVLIDGSCIVNEGMLTGESIPVMKTLLPFTESPEPWKTHSMEDYRRHVLFCGTEVIQAKSSGRGPARAVVLQTGFNTAKGDLVRSILYPRPLNFQLYRDAFKFIVGLSAIGVLGLIYTVCVFTYHKKPVADVVAMALLLLTAAVPPAIPAALTTGTVYAQRRLKKKKIFCITPQRINICGQINLVCFDKTGTLTEDGLDLWGILPSEGSRFQKIHKFPSSTPLPWGPVCGAMASCHSLVVLDKKIQGDPLDLKMFEGTHWEIEESSTARDRAGATDVCIVRPGPNASSAPVEGIAILHQFPFSSGLQRMSVVSQKIGEEQYDLYMKGAPETVSSFCRQETVPSDFLEELKTYTSQGFRVIALAHKVLSLPEDVDVSDLEREEAESGLEFLGLLVMENRLKPETKPVLRELAAARIRSIMVTGDNLQTAVTVARNADMIHEASKVIIVEASEPEGSTPASIAWRLAEGSKASAAAPTEMCANTQEKITLGGESSNYHFAMNGKSYQVLIKHFYSLLPKILLNATVFARMSPGQKSSLVEELQKLDYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSQIPNIQCVPELIREGRAALVASFAVVKYLTLYGLIQFVGTALLFWQLQIFGNYQYLIQDMVITLLVCLTMSLTEAYPKLAPYRPPGQLISPPLLLSVILNVCFTIAMQTCGFLLVKKQPWYVALASWRHCSLGNQTLPPASPGENSTSSSDHSTVLSYEGTTLWPLSSVNCIIVAFVFSKGKPFRKPIYTNYVFSALLTLQLATCLFLFLADMDAVYSGMQFLCTPVIWRVYVLLMLLVTFCVSFFTEDVLLQNKHLWMLIKACVGYQSKSQYRKWQRMLQRDPNWPPVNTKDFAARSTAEVYINPSYEHRD", "length": 1148, "header": "tr|A0A8V0YTN3-1|A0A8V0YFG2_CHICK Computationally mapped isoform of Cation-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP13A5 PE=3 SV=1 CANONICAL=A0A8V0YFG2-1" }, "locus": { "chromosome": "9", "start_pos": 12826849, "end_pos": 12800306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033122.1", "url": "https://www.ensembl.org/id/ENSGALT00010033122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019582.1", "url": "https://www.ensembl.org/id/ENSGALP00010019582.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 729, "start_aa": "Thr", "end_pos": 729, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr729", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424902", "resource": "KEGG Pathway" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MA70-1", "protein_name": "Cation-transporting ATPase", "gene_name": "Atp13a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKSKTDGHQAVLNEGEENELEVFGYQTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADIVLLRTTDEFRRYMRKKVFCLHLSTLKIPISKNPGEPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEDHNKVQVTITVRDKGLQELESRLLVPGDILILPGKISLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACIGVVGFFYALGVYLYHEVPPRETVTMALILLTATVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHSFASGEAVPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEGTGWNMEDGQVASCKYSTADSGTVIKPGPNASQSPVDSITILRQFPFSSGLQRMSVIAQLAGDLRLHVYMKGAPEMVARFCSSETVPKNFPQELRNYTVQGFRVIALAHKTLKMEKVSDVERLAREKVESELAFLGLLIMENRLKNETRPVLQELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVIIVEANEPGDLVPASVTWQLVGTQEPGSEKKVSQGSQQCFRSPCRNHAFRFQDTYIDIGNSSVPCGKGYHFAMSGKSYQVLFHHFYSMLPQILVNGTVFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKVANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYPKLAPYRPAGQLLSPQLLLSVFMNSCFTCIVLVCTFLSVKQQPWYCEVYKYSECFLVNQSNFSTNMGLERNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYTNYLFSLLLTSAVGLTVFILFSDFQDIYRRMEFIPTTTSWRISILVAAFVQFCVAFFVEDAILQNRELWLFIKKEFGFYSKSQYRILQRKLAEDSTWPPTNRTDYAVNGKNGLYINRAYESPEQVPKGKLKLGGQASEQHFWTRL", "length": 1237 }, "evidence": [ { "id": "A0A8V0YFG2", "url": "https://omabrowser.org/oma/group/A0A8V0YFG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LUR3-1", "protein_name": "Cation-transporting ATPase", "gene_name": "ATP13A5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEKSRKDHRALLNPGEENELEVFGYETQNLRRVLCLLISVLTCGVLLLVFYWKPQWRVWATCIPCPLQEADTILLRTTDEFQRYMRKKVICLDLSTLKFPISKNPEEPLLADRHSIINQAVLKPELKLRYIQVQKIRYVWDNVEKRFQKVGLLEDSNSCYDIHHTFGLGLTSEDQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYATAIIILSVISIVLTVYDLRQQSVKLHKLVEDHNKVQVTISVKGQGLQELESRLLVPGDILILSGKSSLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPHTENTTSWKSHSLEDYRKHVLFCGTEVIQVKPTGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVCLAFLGVMGFFYALGVYMYHGVSSRDTVTMALLLLTVTVPPVLPAALTTGIVYAQKRLKRKNIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPAADSCFQEVHSFSSGKALPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFESTFWIMEDCNEDHCKFGISASNIIIKPGPKASQSPVEAITIVRQFPFSSSLQRMSVVAQLAGEDHFHVYMKGAPEMLARFCSSETVPKNFAQELRNYTVQGFRVIALAHKALKMGKFSEVESLTREKVESELTFLGLLIMENRLKKETKPVLKELSEARIRTVMITGDNLQTAITVARNSKMIPQGSQVILVEANEPEESVPASVTWQLVENQECEPGKNETYINIGNSSVPDGERGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTIFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKTANIECVPHLIKEGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLSVLLNTCFTCIVQVCAFLYVKQQPWYCEVYRYSECFLDNHSNFSTNESLERNWTGSATLIPGSVLSFESTTLWPITTINCITAAFIFSKGKPFRKPIYTNYIFSFLLVSALGLTVFILFSDFQDVYSGMEFIPTKTSWRVSVLVAAFTHFCVAFFAEDAILQNRKLWLWIKKELGIYSKSSYRNWQKKLAEDPTWPPTNRTDYSGDGKNGFYINQGYESSEQIPREKLELGGQTTEQHFWTRL", "length": 1219 }, "evidence": [ { "id": "A0A8V0YFG2", "url": "https://omabrowser.org/oma/group/A0A8V0YFG2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3TYU2-1", "protein_name": "Probable cation-transporting ATPase 13A5", "gene_name": "Atp13a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKSKKDGHQAVLNEGEENELEVFGYHTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADTILLRTTDEFRRYMRKKVFCLHLSTLKFPISKNPEEPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTNEEQEVRRLVCGPNSIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEEHNKVQVTITVRDKGLQELESRLLVPGDILILPGKISLPCDAILIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYRKHVLFCGTEVIQVKPSAQGLVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACVGVVGFFYALGVYMYHEVPPRETATMALILLSATVPPVLPAALTIGNVYAQKRLKKEKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHSFASGEAVPWGPLCAAMTSCHSLILLDGTIQGDPLDLKMFEGTGWNMEDSQVASCKFGMADSSTVIKPGPKASQSPVDSITILRQFPFSSGLQRMSVIAQLAGDLHLHVYMKGAPEMVARFCRSETVPKNFSQELRNYTVQGFRVIALAHKTLKMERLSDMDHLAREKVESELAFLGLLIMENRLKKETRPVLKELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVVIVEANEPGDLVPASVTWQLVGTQEPGSGKKDTYIDIGNSSVPAGKGYHFAMSGKSYQVLFHHFYSMLPQILVNGTIFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKTANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYPKLAPYRPAGQLLSPQLLLSVFMNSCFTCIVQVCTFLTVKQQPWYCEVYKYSECFLVNQSNLSANVSLDRNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYANYLFSLLLASAAGLTIFILFCDFQDLYRKMEFIPTPTSWRVSILIAAFVQFCVAFFVEDAVLQNRELWLFIKKEFGFYSKSQYRILQRKLAEDSTWPPVNRTDYAVNGKNGFYVNRAYESPEEVPKGKLKLEEQASEQHFWTRL", "length": 1216 }, "evidence": [ { "id": "A0A8V0YFG2", "url": "https://omabrowser.org/oma/group/A0A8V0YFG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4VNC0-1", "protein_name": "Probable cation-transporting ATPase 13A5", "gene_name": "ATP13A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEENSKKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHELWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPKRKLKLGGQPTEQHFWARL", "length": 1218 }, "evidence": [ { "id": "A0A8V0YFG2", "url": "https://omabrowser.org/oma/group/A0A8V0YFG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "ATPase-coupled monoatomic cation transmembrane transporter activity", "id": "GO:0019829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "P-type ion transporter activity", "id": "GO:0015662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015662", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "polyamine transmembrane transporter activity", "id": "GO:0015203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "P-type transmembrane transporter activity", "id": "GO:0140358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "polyamine transmembrane transport", "id": "GO:1902047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-GGA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-5252122" ], "output_participant_list": [ "R-ALL-5252016" ], "enzyme_list": [ "A0A8V0YFB8-1", "A0A8V0YFG2-1" ], "evidence": [ { "id": "R-GGA-5251989", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5251989" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5252016", "participant_name": "divalent metal cation [cytosol]", "crossref": [ { "id": "60240", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5252122", "participant_name": "divalent metal cation [extracellular region]", "crossref": [ { "id": "60240", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { 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phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": 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} ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of 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"id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": 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"A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": 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"activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": 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"refseq": {}, "gene_names": [ { "name": "GUF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ] } ], "protein_names": [ { "name": "GTP binding elongation factor GUF1", "type": "synonym", "evidence": [ { "id": "A0A8V0YFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1#function" }, { "database": "HAMAP", "id": "MF_03137", "url": "https://hamap.expasy.org/signature/MF_03137" }, { "database": "UniProtKB", "id": "A0A8V0YLH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH8#function" }, { "database": "UniProtKB", "id": "A0A8V0YLX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GUF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1", "locus": { "chromosome": "4", "start_pos": 67111481, "end_pos": 67135099, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013823", "url": "https://www.ensembl.org/id/ENSGALG00010013823" } ] } } ], "crossref": [ { "id": "A0A8V0YFJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01890", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01890", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03699", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03699", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16260", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16260", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422773", "url": "https://www.ncbi.nlm.nih.gov/gene/422773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422773", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVKCDEN", "url": "https://omabrowser.org/oma/group/QVKCDEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFI6", "url": "https://www.orthodb.org/?gene=A0A8V0YFI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YFJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH8", "url": "https://www.orthodb.org/?gene=A0A8V0YLH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLW7", "url": "https://www.orthodb.org/?gene=A0A8V0YLW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLX8", "url": "https://www.orthodb.org/?gene=A0A8V0YLX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43512:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43512:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTGRTVWWWVRLRRPCLTAAPRGPAVWLPTGLAACQRFYSSRDKEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLYAGQVGYLIAGMKEVTEAQIGDTLFMYKQPVEPLPGFKSAKPMVFAGMYPVDQTEYNNLKSALERLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNTSVILTAPTVPYKAVLSSAKLIKEHGKSEITIINPAQFPDKHSVSEYLEPTVLGTIITPQEYIGKIIVLCQDRRAVQKEMLYIDEHRVMLKYLFPLNEIVVDFYDALKSLSSGYASFDYEDAGYQAADLIKMDILINGNPVEELSTIIHNDKAYATGKYLCERLKDAIPRQLFEIAIQAAIGKKIIARETLKAYRKNVVAKCYGGDITRRMKLLKRFSSGNNDVGKSQQEKQITHFSGSKTDSSLSC", "length": 660, "header": "tr|A0A8V0YFJ1-1|A0A8V0YFJ1_CHICK Isoform 1 of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI6/entry", "sequence": { "sequence": "MSLTGRTVWWWVRLRRPCLTAAPRGPAVWLPTGLAACQRFYSSRDKEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLNYLV", "length": 308, "header": "tr|A0A8V0YFI6-1|A0A8V0YFJ1_CHICK Computationally mapped isoform of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "locus": { "chromosome": "4", "start_pos": 67134910, "end_pos": 67128372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033168.1", "url": "https://www.ensembl.org/id/ENSGALT00010033168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019601.1", "url": "https://www.ensembl.org/id/ENSGALP00010019601.1" } ] } }, { "isoform_ac": "A0A8V0YFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1/entry", "sequence": { "sequence": "MSLTGRTVWWWVRLRRPCLTAAPRGPAVWLPTGLAACQRFYSSRDKEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLYAGQVGYLIAGMKEVTEAQIGDTLFMYKQPVEPLPGFKSAKPMVFAGMYPVDQTEYNNLKSALERLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNTSVILTAPTVPYKAVLSSAKLIKEHGKSEITIINPAQFPDKHSVSEYLEPTVLGTIITPQEYIGKIIVLCQDRRAVQKEMLYIDEHRVMLKYLFPLNEIVVDFYDALKSLSSGYASFDYEDAGYQAADLIKMDILINGNPVEELSTIIHNDKAYATGKYLCERLKDAIPRQLFEIAIQAAIGKKIIARETLKAYRKNVVAKCYGGDITRRMKLLKRFSSGNNDVGKSQQEKQITHFSGSKTDSSLSC", "length": 660, "header": "tr|A0A8V0YFJ1-1|A0A8V0YFJ1_CHICK Isoform 1 of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "locus": { "chromosome": "4", "start_pos": 67134910, "end_pos": 67118509, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033181.1", "url": "https://www.ensembl.org/id/ENSGALT00010033181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019606.1", "url": "https://www.ensembl.org/id/ENSGALP00010019606.1" } ] } }, { "isoform_ac": "A0A8V0YLH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH8/entry", "sequence": { "sequence": "MHLLEKNYFSLKGFVRLHTGTVSVVCEKKLSLFQEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLYAGQVGYLIAGMKEVTEAQIGDTLFMYKQPVEPLPGFKSAKPMVFAGMYPVDQTEYNNLKSALERLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNTSVILTAPTVPYKAVLSSAKLIKEHGKSEITIINPAQFPDKHSVSEYLEPTVLGTIITPQEYIGKIIVLCQDRRAVQKEMLYIDEHRVMLKYLFPLNEIVVDFYDALKSLSSGYASFDYEDAGYQAADLIKMDILINGNPVEELSTIIHNDKAYATGKYLCERLKDAIPRQLFEIAIQAAIGKKIIARETLKAYRKNVVAKCYGGDITRRMKLLKRQAEGKKLMRKIGNVEVPRDAFIRVLKRQPEK", "length": 648, "header": "tr|A0A8V0YLH8-1|A0A8V0YLH8_CHICK Computationally mapped isoform of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "locus": { "chromosome": "4", "start_pos": 67134005, "end_pos": 67118993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033188.1", "url": "https://www.ensembl.org/id/ENSGALT00010033188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019610.1", "url": "https://www.ensembl.org/id/ENSGALP00010019610.1" } ] } }, { "isoform_ac": "A0A8V0YLW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW7/entry", "sequence": { "sequence": "MSLTGRTVWWWVRLRRPCLTAAPRGPAVWLPTGLAACQRFYSSRDKEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLNVSCRSNRI", "length": 313, "header": "tr|A0A8V0YLW7-1|A0A8V0YFJ1_CHICK Computationally mapped isoform of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "locus": { "chromosome": "4", "start_pos": 67134910, "end_pos": 67125919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033176.1", "url": "https://www.ensembl.org/id/ENSGALT00010033176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019603.1", "url": "https://www.ensembl.org/id/ENSGALP00010019603.1" } ] } }, { "isoform_ac": "A0A8V0YLX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX8/entry", "sequence": { "sequence": "MSLTGRTVWWWVRLRRPCLTAAPRGPAVWLPTGLAACQRFYSSRDKEKIDMSAYPVESIRNFSIIAHVDHGKSTLADRLLEITGTIAKTDRNKQVLDKLQVERERGITVKAQSASLFYNYKGVNYLLNLIDTPGHVDFNYEVSRSLSACQGVLLVVDANEGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIEKLFDIPVNECIRISAKQGTNIDKVLEKVIEKIPPPQCNTTDPLKALVFDSTFDHYRGVVANIAVFGGEIQKGHRIVSAHTNKRYEVNEVGILTPNEQPTHKLYAGQVGYLIAGMKEVTEAQIGDTLFMYKQPVEPLPGFKSAKPMVFAGMYPVDQTEYNNLKSALERLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNTSVILTAPTVPYKAVLSSAKLIKEHGKSEITIINPAQFPDKHSVSEYLEPTVLGTIITPQEYIGKIIVLCQDRRAVQKEMLYIDEHRVMLKYLFPLNEIVVDFYDALKSLSSGYASFDYEDAGYQAADLIKMDILINGNPVEELSTIIHNDKAYATGKYLCERLKDAIPRQLFEIAIQAAIGKKIIARETLKAYRKNVVAKCYGGDITRRMKLLKRQAEGKKLMRKIGNVEVPRDAFIRVLKRQPEK", "length": 660, "header": "tr|A0A8V0YLX8-1|A0A8V0YLX8_CHICK Computationally mapped isoform of GTP binding elongation factor GUF1 OS=Gallus gallus OX=9031 GN=GUF1 PE=3 SV=1 CANONICAL=A0A8V0YFJ1-1" }, "locus": { "chromosome": "4", "start_pos": 67134910, "end_pos": 67118993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033195.1", "url": "https://www.ensembl.org/id/ENSGALT00010033195.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019613.1", "url": "https://www.ensembl.org/id/ENSGALP00010019613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422773", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32T7J6-1", "protein_name": "Translation factor GUF1, mitochondrial isoform X1", "gene_name": "guf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLLRPHGLFLPFIKRLTDIKVCRVKRRSQGCTYNITVIRHRWMKSLGSVRDLSSSATEKETFDMSKFPAERIRNFSIIAHIDHGKSTLADRLLEMTGAIAKTASNKQVLDKLQVERERGITVKAQTASLFYQHHGQTYLLNLIDTPGHVDFSYEVSRSISACQGVLLIVDANQGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIETVFDIPKEECIRISAKLGTNVEQVLQEVVKRIPPPAVRVEDPFKGLVFDSTFDHYRGVVANIALFGGRVSRGDRIVSAHLGKSFEVNELGILRPDQHPTETLYAGQVGYVIAGMKEVKEAQIGDTLYLHKQPVEALPGFKPAKPMVFAGMYPMDQSEYTALRSALEKLTLNDSSVSIQKDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVIITAPTVPYKAVLASAKLIKEYGEEVITIINPAQFPDKSKVLEYLEPMVTGTIITPDDFTGKIMTLCQGRRGIQKNMVYIDDHRVMMKYVFPLNEIVVDFYDQLKSMSSGYASFDYEDAGYEAADLIKMDFLLNGQPVEELAVIVHKLWFLLIFRDKAYSSGKAICERLSNSIPRQMFEIAVQAAIGSKIIARETIKAFRKNVLAKCYGGDITRKMKLLKKQAEGKKKMRRIGNIDVPKDAFISVLKRK", "length": 680 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6QLJ3-1", "protein_name": "Translation factor GUF1, mitochondrial", "gene_name": "GUF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWTLAGQGWWRGRALAAWVTEAARKGLLWPHLAPARGTAAESRAPDRCYSSADRKEKIDMSCFPVENTRNFSIIAHVDHGKSTLADRLLELTGAIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNYEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSIIPVINKIDLKNADPERVEKQIEKVFDIPGDECIKISAKLGTNVESVLDAVIKRIPFPKAHCRNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLYLHKQPVEPLPGFKSAKPMVFAGMYPVDQSEYNNLKSAIEKLTLNDSSVVVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYREKEITIINPAQFPDKSKVTEYLEPVVLGTIITPDEYTGKIMMLCQARRAVQKNMMYIDQNRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGSIVEELVTVVHKDKAYSVGKAICERLKDSLPRQLFEIAIQAALGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKVGNVEVPKDAFIKVLKTQSDK", "length": 669 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0G189-1", "protein_name": "Translation factor GUF1 homolog, mitochondrial", "gene_name": "guf1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSRLLNRGNGGVNKNITSGLLLRRTTTTTTRLSYINNSPTLSIRSFCSKSTTITSDEKLDLSGYTTDRIRNFSIIAHIDHGKTTLSTKLLSLTGTLPKSIYGSGEDSLVQKEKSEERREQYLDKLQVEKERGITVKAQTCTMKYRNKEDGKDYLLNLIDTPGHVDFSYEVSRSLMACQGALLVVDAVQGVQAQTMANYYLALDSGLEVIPVINKIDLPTADVERVKQELKDAFGFHPDDAVLVSAKTGVGITDILPAVIDRIPPPQEPTKSPKVPFKALLFDSWFDRFRGVICLIKVVDGKVKKGDSIVSAGNKQTYEVFDVGIMHPEQRPAPSLFTGQVGYITPGMKTSKEARVGDTFYMKDFPVEPLPGFQPAKQMVFAGIYPVDSLDYTQLRESFEKLMLTDSSISMTNETSVALGMGFRCGFLGLLHMDVVLQRLEQEYGQVVIATPPTVPYRCLLTDGKEILISNPAGYPSAEHLSKTFEPMVTGHVTLPTEYFGAVVKLCMDSRGILTNQETLEGNRTRITFNFPLGEIVTDFYDNLKRISSGYASLDYEDNGYQESDVAKVRVLLNGEEVDSLSAIVHKSNAQRYSRSLVKRLRKVIDRQMFQVNIQAMVGSDVQARETISAMRKDVTAKCYGGDITRRRKLLDKQKEGKKRMKQMGCVELSQEGFLKLMKSTNDDD", "length": 685 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "D3ZHF8-1", "protein_name": "GTP binding elongation factor GUF1", "gene_name": "Guf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWALAGRALAPWAAGAARLLPPCPRHAGVLEPGVACRLFSAAELKEKPDMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTQKNKQVLDKLQVERERGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQAVIERIPPPKVHRANPLKALVFDSTFDQYRGVVASIALFDGMLSKGDKIVSAHTKKTYEVNQVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYKEKEITIINPAQFPDKSKVTEYLEPVVLGTVITPTEYTGKIMELCQARRAIQKNMTFIDENRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTADLIKMDILLNGNIVEELVTVVHREKAYTVGKSICERLKDSLPRQLFEIAVQAAIGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNIEIPKNAFIKVLKTQPNK", "length": 659 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S3T1-1", "protein_name": "GTP binding elongation factor GUF1", "gene_name": "GUF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWARAGPGWWPGRTLAAWASRSAGLGPPGALPASALGPAAEPRAPDRPFSSADRQEKIDMSRFPVENTRNFSIIAHVDHGKSTLADRFLELTGAIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVEKQIEKVFDIPSDECIKISAKLGTNVESVLQAVIKRIPPPKAHRKNSLRALVFDSTYDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPAYKLYAGQVGYLIAGMKDVTEAQIGDTLYLHKQPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKNAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYREKEITIINPAQFPDKSKVTEYLEPIVLGTIITPDEYTGKIIMLCQARRAVQKNMMYIDQTRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNIVEELVTVVHKDKAYSVGKTICERLKDSLPRQLFEIAIQAAIGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNIEVPKDAFIKVLKTQSDK", "length": 669 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P46943-1", "protein_name": "Translation factor GUF1, mitochondrial", "gene_name": "GUF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLENYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCSMFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFYLAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLPAIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGSVRKNDKVICAQTKEKYEVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFEEQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLHASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHEPFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGKLKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKFKEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKKHMKTVGNIQINQEAYQAFLRR", "length": 645 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8C3X4-1", "protein_name": "Translation factor Guf1, mitochondrial", "gene_name": "Guf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWALVGRALAPWAAGARHAAASEPRAACRLFSAAELKEKPDMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTKKNKQVLDKLQVERERGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQAVIERIPPPKVHRENPLKALVFDSTFDQYRGVIANIALFDGVVSKGDKIVSAHTKKAYEVNEVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYKEKEITIINPAQFPEKSQVTEYLEPVVLGTVITPTEYTGKIMALCQARRAIQKNMTFIDENRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNMVEELVTVVHREKAYTVGKSICERLKESLPRQLYEIAIQAAVGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQSEGKKKLRKIGNIEIPKDAFIKVLKTQPNK", "length": 651 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N442-1", "protein_name": "Translation factor GUF1, mitochondrial", "gene_name": "GUF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWTLVGRGWGCARALAPRATGAALLVAPGPRSAPTLGAAPESWATDRLYSSAEFKEKLDMSRFPVENIRNFSIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVENQIEKVFDIPSDECIKISAKLGTNVESVLQAIIERIPPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLCLHKQPVEPLPGFKSAKPMVFAGMYPLDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSSKLIKEHREKEITIINPAQFPDKSKVTEYLEPVVLGTIITPDEYTGKIMMLCEARRAVQKNMIFIDQNRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNTVEELVTVVHKDKAHSIGKAICERLKDSLPRQLFEIAIQAAIGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNVEVPKDAFIKVLKTQSSK", "length": 669 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRH6-1", "protein_name": "Translation factor waclaw, mitochondrial", "gene_name": "waw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIVGYSVFFHHTVTRRTWCAVTIFFCRQRNVNSAMIRAISIRWLLQRPGDKRHSAWLVARSKSLLVRNLSTTNQVKGETEEPSQADLLREFAHMPVERIRNFSIIAHVDHGKSTLADRLLELTGAIARNGGQHQVLDNLQVERERGITVKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHGVQAQTVANYHLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDPDEVLRVSAKLGTGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDIQSLATKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQAVAAAGSYRPQQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVFCQRLEQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMDISNAALFPEPHSIKEYYEPLVLGTIITPTEYVGQVISLCVERRGLQQSSVNIDDTRVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYEDHGYHPSHLVRLDIHLNGKPVEELCRIVHVSKATGVARQMVLKLRELIPKQMVQIAIQACVGSKVLARETIKAYRKDVTAKLYGGDVTRRMKLLKQQAEGKKKMRMFANIRVPHETFINVLKR", "length": 696 }, "evidence": [ { "id": "A0A8V0YFJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YFJ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "mitochondrial ribosome binding", "id": "GO:0097177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", 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"evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { 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}, { "id": "A0A8V0YNH0", "url": "https://www.orthodb.org/?gene=A0A8V0YNH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46055:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46055:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELCTMLQGHGHPLKMDKSTILQRTIDFLQKQKEITAQTEACEIRQDWKPSFLSNEEFTQLMLEALDGFLIALTTDGIIIYVSDSVSSLLGHLPSDLVDQNILNFLPEREQSEVYKLLSPRVLMTEPVAADFLNVEKQVEFCCHLARGSLDPNEPLTYEYVKFVVDFKYFTHVPTPSCNGFESAIARAFRSATEEQICLVATVRLVTPQFLKELCNVEEPCEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHADDLELLARCHEHLMQFGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHLVVSYAEVRAEKRRDLGLEESSIELASSSIKSHGSYLEVGRCGSSQDASREGMSLSSHSSRRSSHTALSDSASTSSMRHTDTSTPTRPAVPEKAALRLAAAGSAQAIATPPATGEHLPQQPAVPSQQTVMPVYQFPAPLGMMHQLKEQLEERTRILQADIKTQQEELHVIKEQLQLVQDSNLQMLMQQPIPLVFNNAQRQSPRRAPPPSRQPSTKKAPQPGPMAKHYGGPPVSTPRPFLREPCSTPSQVPQQQQHLMRGNQAQPTCLPGQTSISVPLYNNPMVFSQAQPITVAAQLPTDVRERQMQSDYSQDRSLRMLLDQSIQAMVPAANGSTQPTLSSSSRQLGKFVAEQQPLPPTTQMQPISGSTVRPPAPSPVFSPSVMLPHGSFVSHPGSTPLHLHPWPQQQVQQHRLYLQMQGAEAVPGGPSPRVFQPPHLPQQNPLSYFLHPQPQGRHAQGQPCNLPDLPEMQLP", "length": 822, "header": "tr|A0A8V0YFJ6-1|A0A8V0YFJ6_CHICK Isoform 1 of PAS domain containing repressor 1 OS=Gallus gallus OX=9031 GN=PASD1 PE=4 SV=1 CANONICAL=A0A8V0YFJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6/entry", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELCTMLQGHGHPLKMDKSTILQRTIDFLQKQKEITAQTEACEIRQDWKPSFLSNEEFTQLMLEALDGFLIALTTDGIIIYVSDSVSSLLGHLPSDLVDQNILNFLPEREQSEVYKLLSPRVLMTEPVAADFLNVEKQVEFCCHLARGSLDPNEPLTYEYVKFVVDFKYFTHVPTPSCNGFESAIARAFRSATEEQICLVATVRLVTPQFLKELCNVEEPCEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHADDLELLARCHEHLMQFGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHLVVSYAEVRAEKRRDLGLEESSIELASSSIKSHGSYLEVGRCGSSQDASREGMSLSSHSSRRSSHTALSDSASTSSMRHTDTSTPTRPAVPEKAALRLAAAGSAQAIATPPATGEHLPQQPAVPSQQTVMPVYQFPAPLGMMHQLKEQLEERTRILQADIKTQQEELHVIKEQLQLVQDSNLQMLMQQPIPLVFNNAQRQSPRRAPPPSRQPSTKKAPQPGPMAKHYGGPPVSTPRPFLREPCSTPSQVPQQQQHLMRGNQAQPTCLPGQTSISVPLYNNPMVFSQAQPITVAAQLPTDVRERQMQSDYSQDRSLRMLLDQSIQAMVPAANGSTQPTLSSSSRQLGKFVAEQQPLPPTTQMQPISGSTVRPPAPSPVFSPSVMLPHGSFVSHPGSTPLHLHPWPQQQVQQHRLYLQMQGAEAVPGGPSPRVFQPPHLPQQNPLSYFLHPQPQGRHAQGQPCNLPDLPEMQLP", "length": 822, "header": "tr|A0A8V0YFJ6-1|A0A8V0YFJ6_CHICK Isoform 1 of PAS domain containing repressor 1 OS=Gallus gallus OX=9031 GN=PASD1 PE=4 SV=1 CANONICAL=A0A8V0YFJ6-1" }, "locus": { "chromosome": "4", "start_pos": 17383688, "end_pos": 17361846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030452.1", "url": "https://www.ensembl.org/id/ENSGALT00010030452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017663.1", "url": "https://www.ensembl.org/id/ENSGALP00010017663.1" } ] } }, { "isoform_ac": "A0A8V0YNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH0/entry", "sequence": { "sequence": "MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELCTMLQGHGHPLKMDKSTILQRTIDFLQKQKEITAQTEACEIRQDWKPSFLSNEEFTQLMLEALDGFLIALTTDGIIIYVSDSVSSLLGHLPSDLVDQNILNFLPEREQSEVYKLLSPRVLMTEPVAADFLNVEKQVEFCCHLARGSLDPNEPLTYEYVKFVVDFKYFTHVPTPSCNGFESAIARAFRSATEEQICLVATVRLVTPQFLKELCNVEEPCEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHADDLELLARCHEHLMQFGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHLVVSYAEVRAEKRRDLGLEESSIELASSSIKSHGSYLEVGRCGSSQDASREGMSLSSHSSRRSSHTALSDSASTSSMRHTDTSTPTRPAVPEKAALRLAAAGSAQVGAAEGSRWQAVVSPLEGSDPQLQAIATPPATGEHLPQQPAVPSQQTVMPVYQFPAPLGMMHQLKEQLEERTRILQADIKTQQEELHVIKEQLQLVQDSNLQMLMQQPIPLVFNNAQRQSPRRAPPPSRQPSTKKAPQPGPMAKHYGGPPVSTPRPFLREPCSTPSQVPQQQQHLMRGNQAQPTCLPGQTSISVPLYNNPMVFSQAQPITVAAQLPTDVRERQMQSDYSQDRSLRFVAEQQPLPPTTQMQPISGSTVRPPAPSPVFSPSVMLPHGSFVSHPGSTPLHLHPWPQQQVQQHRLYLQMQGAEAVPGGPSPRVFQPPHLPQQNPLSYFLHPQPQGRHAQGQPCNLPDLPEMQLP", "length": 815, "header": "tr|A0A8V0YNH0-1|A0A8V0YNH0_CHICK Computationally mapped isoform of PAS domain containing repressor 1 OS=Gallus gallus OX=9031 GN=PASD1 PE=4 SV=1 CANONICAL=A0A8V0YFJ6-1" }, "locus": { "chromosome": "4", "start_pos": 17383688, "end_pos": 17361846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030453.1", "url": "https://www.ensembl.org/id/ENSGALT00010030453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017665.1", "url": "https://www.ensembl.org/id/ENSGALP00010017665.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 595, "start_aa": "Thr", "end_pos": 595, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr595", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "CLOCK-BMAL transcription complex", "id": "GO:1990513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 61, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ6" }, { "id": "PS50112", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAS", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 155, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 595 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFR6-1", "uniprot_ac": "A0A8V0YFR6", "uniprot_id": "A0A8V0YFR6_CHICK", "mass": { "chemical_mass": 155983.0, "monoisotopic_mass": 155983.0 }, "refseq": { "ac": "XP_025009505", "name": "TRAF2 and NCK-interacting protein kinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009505" }, "gene_names": [ { "name": "TNIK", "type": "recommended", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "name": "TNIK", "type": "synonym", "evidence": [ { "id": "XP_025009505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009505" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6/entry#names_and_taxonomy" } ] }, { "name": "TRAF2 and NCK-interacting protein kinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025009505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009505" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNIK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6", "locus": { "chromosome": "9", "start_pos": 19405916, "end_pos": 19272415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013911", "url": "https://www.ensembl.org/id/ENSGALG00010013911" } ] } } ], "crossref": [ { "id": "cd06637", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06637", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424987", "url": "https://www.ncbi.nlm.nih.gov/gene/424987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDTGTEY", "url": "https://omabrowser.org/oma/group/MDTGTEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFR6", "url": "https://www.orthodb.org/?gene=A0A8V0YFR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFU3", "url": "https://www.orthodb.org/?gene=A0A8V0YFU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YLQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLR5", "url": "https://www.orthodb.org/?gene=A0A8V0YLR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLS6", "url": "https://www.orthodb.org/?gene=A0A8V0YLS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT0", "url": "https://www.orthodb.org/?gene=A0A8V0YLT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTY6", "url": "https://www.orthodb.org/?gene=A0A8V0YTY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025009505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPASYKKAIDEGEMDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1367, "header": "tr|A0A8V0YFR6-1|A0A8V0YFR6_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPASYKKAIDEGEMDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1367, "header": "tr|A0A8V0YFR6-1|A0A8V0YFR6_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033373.1", "url": "https://www.ensembl.org/id/ENSGALT00010033373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019689.1", "url": "https://www.ensembl.org/id/ENSGALP00010019689.1" } ] } }, { "isoform_ac": "A0A8V0YFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU3/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPADLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1276, "header": "tr|A0A8V0YFU3-1|A0A8V0YFU3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033419.1", "url": "https://www.ensembl.org/id/ENSGALT00010033419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019715.1", "url": "https://www.ensembl.org/id/ENSGALP00010019715.1" } ] } }, { "isoform_ac": "A0A8V0YLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ5/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPASYKKAIDEGEMDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1258, "header": "tr|A0A8V0YLQ5-1|A0A8V0YLQ5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033353.1", "url": "https://www.ensembl.org/id/ENSGALT00010033353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019682.1", "url": "https://www.ensembl.org/id/ENSGALP00010019682.1" } ] } }, { "isoform_ac": "A0A8V0YLR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR5/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPASYKKAIDEHDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1365, "header": "tr|A0A8V0YLR5-1|A0A8V0YLR5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033383.1", "url": "https://www.ensembl.org/id/ENSGALT00010033383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019693.1", "url": "https://www.ensembl.org/id/ENSGALP00010019693.1" } ] } }, { "isoform_ac": "A0A8V0YLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS6/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPASYKKAIDEDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1364, "header": "tr|A0A8V0YLS6-1|A0A8V0YLS6_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033402.1", "url": "https://www.ensembl.org/id/ENSGALT00010033402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019704.1", "url": "https://www.ensembl.org/id/ENSGALP00010019704.1" } ] } }, { "isoform_ac": "A0A8V0YLT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT0/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPADLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVRETSGEKKRSGHAASNGFAGHINLPDLVQQSHSPAGTPTEALGRVSTHAQDMDSVPEYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1356, "header": "tr|A0A8V0YLT0-1|A0A8V0YLT0_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033409.1", "url": "https://www.ensembl.org/id/ENSGALT00010033409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019709.1", "url": "https://www.ensembl.org/id/ENSGALP00010019709.1" } ] } }, { "isoform_ac": "A0A8V0YTY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY6/entry", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPTTEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQAERLQRQLQQERDYLVSLQQQQQQQRQDQRPAEKKPLYHYKEGINASEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISSVQPARTPPLLRPVDPQIPHLVTVKSQGSSLSGSQSLHEQPAKGMAGFQEALTVTSHRTEMPRQNSDPTSENPPLPPRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPIIESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERNRVRGNVKPEGSPVLSHEPPKIKQEDNRDVTRPSRPADLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGENETHDGTVPVSDIPRLIPTGIPGSNEPYNLGMVTTHGLETSHADTFSNISREGTLMVREYGMGSSTKASFTPFVDTRVYQTSPTDEDEDEDEESSATALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1301, "header": "tr|A0A8V0YTY6-1|A0A8V0YFR6_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TNIK PE=3 SV=1 CANONICAL=A0A8V0YFR6-1" }, "locus": { "chromosome": "9", "start_pos": 19405109, "end_pos": 19272639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033363.1", "url": "https://www.ensembl.org/id/ENSGALT00010033363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019684.1", "url": "https://www.ensembl.org/id/ENSGALP00010019684.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 739, "start_aa": "Thr", "end_pos": 739, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr739", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K490-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tnik", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHGQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPLEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPQLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPVLESSLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPSKVKPEESRDIPRPSRPASYKKAIDEDLTALAKELRELRIEETNRPLKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGKNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDTGAEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1360 }, "evidence": [ { "id": "A0A8V0YFR6", "url": "https://omabrowser.org/oma/group/A0A8V0YFR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKE5-1", "protein_name": "TRAF2 and NCK-interacting protein kinase", "gene_name": "TNIK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "length": 1360 }, "evidence": [ { "id": "A0A8V0YFR6", "url": "https://omabrowser.org/oma/group/A0A8V0YFR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" }, { "name": "positive regulation of microvillus assembly", "id": "GO:1903698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903698", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": 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Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231879.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231879" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC768760", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGAGCGRGQLSLPSLLLLLAFLAAPHFTGGQLRYAVPEELEHGAFVANLGEDLGLDVSTLSARRFRIVTGAGVRQHLEVNLENGILFVNERIDREEVCETGGTCLLHLQLLVESPLELYRVEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELSPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQPSYSIYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTLFSLAPDTGELRTLRSFLEQDAARQRLVVQVRDGGQPALSATVSLLLSVVETMPQTLSDFSNFSLPPEASSSSPLTLYLLVSLGSISFTFLLAILILTAIRCRGMRYPWQGDSCCCCPRTRRSPDGLKTSNLASQPGASVAAHLDVPDGGPPGYCYKLCLGPESAQSDFMFLKPCSLPRNNEKGPGNLPAAGKRSRPGQPLHGPKQIKQPNTDWLPPTVQRPALKSSQSLEDVGEIRRALQKEHERLCTLVTPVAEFQKASAGTNSVWAPQYGPLYSGHIPAPDYQHNVYIPGTPTLLSSKDGPLVPGRESKNSFSTFGKKKKMTTYYDMPDSVVINNDLK", "length": 962, "header": "tr|A0A8V0YFV1-1|A0A8V0YFV1_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC768760 PE=4 SV=1 CANONICAL=A0A8V0YFV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1/entry", "sequence": { "sequence": "MRAGAGCGRGQLSLPSLLLLLAFLAAPHFTGGQLRYAVPEELEHGAFVANLGEDLGLDVSTLSARRFRIVTGAGVRQHLEVNLENGILFVNERIDREEVCETGGTCLLHLQLLVESPLELYRVEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELSPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQPSYSIYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTLFSLAPDTGELRTLRSFLEQDAARQRLVVQVRDGGQPALSATVSLLLSVVETMPQTLSDFSNFSLPPEASSSSPLTLYLLVSLGSISFTFLLAILILTAIRCRGMRYPWQGDSCCCCPRTRRSPDGLKTSNLASQPGASVAAHLDVPDGGPPGYCYKLCLGPESAQSDFMFLKPCSLPRNNEKGPGNLPAAGKRSRPGQPLHGPKQIKQPNTDWLPPTVQRPALKSSQSLEDVGEIRRALQKEHERLCTLVTPVAEFQKASAGTNSVWAPQYGPLYSGHIPAPDYQHNVYIPGTPTLLSSKDGPLVPGRESKNSFSTFGKKKKMTTYYDMPDSVVINNDLK", "length": 962, "header": "tr|A0A8V0YFV1-1|A0A8V0YFV1_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC768760 PE=4 SV=1 CANONICAL=A0A8V0YFV1-1" }, "locus": { "chromosome": "13", "start_pos": 909275, "end_pos": 905110, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026259.1", "url": "https://www.ensembl.org/id/ENSGALT00010026259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014883.1", "url": "https://www.ensembl.org/id/ENSGALP00010014883.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768760", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F647-1", "protein_name": "Protocadherin gamma-C3", "gene_name": "si:ch73-233f7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRRLPRRRWTLAGQIVCLLLCACALDRVLAQIRYSIPEELEHGAFVGNIAEDLGLDVAKLSSRRFRIVSGARKQYLEVNLENGILFVNEKIDREELCEQSPVCFLHLQVVIENPLELYRVEVEILDVNDNAPSFPWSEFNLEITESAAPGSRFPLESAQDLDVGSNSLRSYLLSANQHFVLDIQTRNDGSKFAELVLQSQLDREQQKMHEMVLTAVDGGSPLRSGTAQITVTVLDANDNVPVFDRSVYRVSLVENAPRGTLVLKLNATDLDEGANGEITYSFSGHAPLKVRELFSVDSHSGEIRVKGIVDYERASVYELYVQAKDKGPSAVAVHCKVLVDILDVNDNAPEVILTSVSTPVQEDAPPGTVIAVISVMDRDSGENGAVDCQIPGNVPFQLHSSFKNYYTLVTSEFLDRESVSEYNITLTARDLGSPPLSTRKTILVQVSDINDNPPRFIQPSYTVYVTENNAPGASICSVTAFDPDSNQNAYLSYSILEGQIQGMPVSTYVSINSDNGNIYALRSFDYEQLRNFQIRVQAQDAGFPPLSSNVTVNVFVLDQNDNAPVILSPLPRNGSVATEMVPRSVDSGYLVAKITALDADAGQNSRLSYQVLQATDPGLFSVALYTGEIRTIRRFVDKDAIRQRLVILVKDNGQPPLSATVSIILSVVDSVPESLSDFGDLSLSPQPPSNLALYLIVSLSTVSLIFLVAIIVLAAVKCYKDRDSLGGYALSSLSTACCSFEPEPPAEVFKKSNLNLQISTGAKVPTNCMEVNSNAGNLSQAYCYKVCLTPESAKSDFMFLKPCSPGTPRNNAARGADNLALSSQSRCSSVNNGATTPNELKQANTDWALTKNQTSSVKSCNSINMDGTLVRKAMQAEPEHYMGQMAAGQYWTWGTRSKEYRNQSPAGGVSQRAWTPHYTPQHNPTQNQHHLQQQQQQQATAQSHPNPPPDYQHNVYIPGTPSGFCTLRPSHRSELHVHNSFSTFGKKRRFISPSSFDPRDDTGAEVINNDLYNE", "length": 1015 }, "evidence": [ { "id": "A0A8V0YFV1", "url": "https://omabrowser.org/oma/group/A0A8V0YFV1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV1" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 137, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 683, "end_pos": 685 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFV5-1", "uniprot_ac": "A0A8V0YFV5", "uniprot_id": "A0A8V0YFV5_CHICK", "mass": { "chemical_mass": 129620.0, "monoisotopic_mass": 129620.0 }, "refseq": { "ac": "XP_003643030", "name": "integrin alpha-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643030" }, "gene_names": [ { "name": "ITGA2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5" } ] }, { "name": "ITGA2", "type": "synonym", "evidence": [ { "id": "XP_003643030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643030" } ] } ], "protein_names": [ { "name": "Integrin alpha-2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry#names_and_taxonomy" } ] }, { "name": "CD49 antigen-like family member B", "type": "synonym", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry#names_and_taxonomy" } ] }, { "name": "Collagen receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry#names_and_taxonomy" } ] }, { "name": "Platelet membrane glycoprotein Ia", "type": "synonym", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry#names_and_taxonomy" } ] }, { "name": "VLA-2 subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry#names_and_taxonomy" } ] }, { "name": "integrin alpha-2", "type": "synonym", "evidence": [ { "id": "XP_003643030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643030" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643030.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643030" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5", "locus": { "chromosome": "Z", "start_pos": 16464661, "end_pos": 16402199, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012771", "url": "https://www.ensembl.org/id/ENSGALG00010012771" } ] } } ], "crossref": [ { "id": "A0A8V0YFV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857227", "url": "https://www.ncbi.nlm.nih.gov/gene/100857227", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857227", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQYASQW", "url": "https://omabrowser.org/oma/group/IQYASQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFV5", "url": "https://www.orthodb.org/?gene=A0A8V0YFV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNQ2", "url": "https://www.orthodb.org/?gene=A0A8V0YNQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASASAALLLALGFLHNCCEAYNVGLLKAKIFSGPSREQFGYAVQQFINEQGKWLLVGSPWSGYPVNRTGDIYACPVGTPKTTCKKLNLQALINIPNVTEIKEDMNLGLTLIQNSKTGGFLTCGPLWAQQCGSQHYATGVCSEISPSFQILRSFSPAVQKCSSVIDIVVVCDESNSIYPWDAVRAFLKKFVQGLDIGINKTQVGLIQYANNPRVVFKLNEYRTKDDVVNATEKTFQQGGDLTNTFKAIDYARQHAFSAESGGRPTATKVMVVVTDGESHDGSNLKTVIGRCNEDNITRFGIAVLGYLIRNELDTKNLIKEIKGIASHPTEKYFFNVSSEAALLEEAGTLGERIFSIEGTDQGDTFQMEMSQVGFSAYFSEKKDVLLLGAVGAYDWSGTVLQESSNRVTTFPSNVFEKILQDRNHSSYLGYSVAVLSTQSSIYFVAGAPRSNYTGRVVVYDVDSQGNISIVQSQRGEQIGSYFGSVVCSVDVNKDSVTDVLLVGAPMFMNDMKKEEGRVYMFSITKGILDQQELLQGPQGSENARFGSAIAALTDIDLDGFNDIVIGAPLENQNSGAIYIYNGFQKTIRTKYSQKILGSDSAFGKRLKFFGRSVDGHRDLDDNDITDVSVGADGNVVLLWSQSIANVSVIALFTPEKISLLNKNTEITVKICFQATFRPAKRDNQVAIKCNATLDADLQSSRVTSRGLFKENNERYMQRDVMVTHSMNCVQDIFNVQEPSDAVNSLNVRIDIGLANPGTSPVLDTSSPASVAYSIPFIKDCGEDELCICDLVLNIQQKGDDGKQQFIVSSKNKRLTFNVKLRNKKENAYNTRIQATFSDNLFFASSSLPSDGTEVSCQTGTSQTTVICQISYPVFRTGQQVSFDISFDFNLKNLQNMAVLSFHALSESKEEQEPDNQISLSIPLRYDAEIHFTRLANINFYEVYSGHNIPSTVNNFEDIGPMFNFSVKVTTGSIPVKMASVKIHLPELTSKDNALMYITAVDTDQARGVTCQVQINPLQIGIRPYSASFKKENLRAVKELNCKNAKCSTITCKLEDLMLKGEYFVNVSTRIWNSTFAVSTFQTVQLFAEAEINVHNTDLFIIGENTLTIPVTIIKPDEKAEIPIGVVIGSILAGLLLLLALVAVLWKLGFFKRQYEKMTQDIEDIDEITELTKDKD", "length": 1175, "header": "tr|A0A8V0YFV5-1|A0A8V0YFV5_CHICK Isoform 1 of Integrin alpha-2 OS=Gallus gallus OX=9031 GN=ITGA2 PE=1 SV=1 CANONICAL=A0A8V0YFV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV5/entry", "sequence": { "sequence": "MASASAALLLALGFLHNCCEAYNVGLLKAKIFSGPSREQFGYAVQQFINEQGKWLLVGSPWSGYPVNRTGDIYACPVGTPKTTCKKLNLQALINIPNVTEIKEDMNLGLTLIQNSKTGGFLTCGPLWAQQCGSQHYATGVCSEISPSFQILRSFSPAVQKCSSVIDIVVVCDESNSIYPWDAVRAFLKKFVQGLDIGINKTQVGLIQYANNPRVVFKLNEYRTKDDVVNATEKTFQQGGDLTNTFKAIDYARQHAFSAESGGRPTATKVMVVVTDGESHDGSNLKTVIGRCNEDNITRFGIAVLGYLIRNELDTKNLIKEIKGIASHPTEKYFFNVSSEAALLEEAGTLGERIFSIEGTDQGDTFQMEMSQVGFSAYFSEKKDVLLLGAVGAYDWSGTVLQESSNRVTTFPSNVFEKILQDRNHSSYLGYSVAVLSTQSSIYFVAGAPRSNYTGRVVVYDVDSQGNISIVQSQRGEQIGSYFGSVVCSVDVNKDSVTDVLLVGAPMFMNDMKKEEGRVYMFSITKGILDQQELLQGPQGSENARFGSAIAALTDIDLDGFNDIVIGAPLENQNSGAIYIYNGFQKTIRTKYSQKILGSDSAFGKRLKFFGRSVDGHRDLDDNDITDVSVGADGNVVLLWSQSIANVSVIALFTPEKISLLNKNTEITVKICFQATFRPAKRDNQVAIKCNATLDADLQSSRVTSRGLFKENNERYMQRDVMVTHSMNCVQDIFNVQEPSDAVNSLNVRIDIGLANPGTSPVLDTSSPASVAYSIPFIKDCGEDELCICDLVLNIQQKGDDGKQQFIVSSKNKRLTFNVKLRNKKENAYNTRIQATFSDNLFFASSSLPSDGTEVSCQTGTSQTTVICQISYPVFRTGQQVSFDISFDFNLKNLQNMAVLSFHALSESKEEQEPDNQISLSIPLRYDAEIHFTRLANINFYEVYSGHNIPSTVNNFEDIGPMFNFSVKVTTGSIPVKMASVKIHLPELTSKDNALMYITAVDTDQARGVTCQVQINPLQIGIRPYSASFKKENLRAVKELNCKNAKCSTITCKLEDLMLKGEYFVNVSTRIWNSTFAVSTFQTVQLFAEAEINVHNTDLFIIGENTLTIPVTIIKPDEKAEIPIGVVIGSILAGLLLLLALVAVLWKLGFFKRQYEKMTQDIEDIDEITELTKDKD", "length": 1175, "header": "tr|A0A8V0YFV5-1|A0A8V0YFV5_CHICK Isoform 1 of Integrin alpha-2 OS=Gallus gallus OX=9031 GN=ITGA2 PE=1 SV=1 CANONICAL=A0A8V0YFV5-1" }, "locus": { "chromosome": "Z", "start_pos": 16464167, "end_pos": 16402289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030619.1", "url": "https://www.ensembl.org/id/ENSGALT00010030619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017759.1", "url": "https://www.ensembl.org/id/ENSGALP00010017759.1" } ] } }, { "isoform_ac": "A0A8V0YNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ2/entry", "sequence": { "sequence": "MKKLLVGSPWSGYPVNRTGDIYACPVGTPKTTCKKLNLQALINIPNVTEIKEDMNLGLTLIQNSKTGGFLTCGPLWAQQCGSQHYATGVCSEISPSFQILRSFSPAVQKCSSVIDIVVVCDESNSIYPWDAVRAFLKKFVQGLDIGINKTQVGLIQYANNPRVVFKLNEYRTKDDVVNATEKTFQQGGDLTNTFKAIDYARQHAFSAESGGRPTATKVMVVVTDGESHDGSNLKTVIGRCNEDNITRFGIAVLGYLIRNELDTKNLIKEIKGIASHPTEKYFFNVSSEAALLEEAGTLGERIFSIEGTDQGDTFQMEMSQVGFSAYFSEKKDVLLLGAVGAYDWSGTVLQESSNRVTTFPSNVFEKILQDRNHSSYLGYSVAVLSTQSSIYFVAGAPRSNYTGRVVVYDVDSQGNISIVQSQRGEQIGSYFGSVVCSVDVNKDSVTDVLLVGAPMFMNDMKKEEGRVYMFSITKGILDQQELLQGPQGSENARFGSAIAALTDIDLDGFNDIVIGAPLENQNSGAIYIYNGFQKTIRTKYSQKILGSDSAFGKRLKFFGRSVDGHRDLDDNDITDVSVGADGNVVLLWSQSIANVSVIALFTPEKISLLNKNTEITVKICFQATFRPAKRDNQVAIKCNATLDADLQSSRVTSRGLFKENNERYMQRDVMVTHSMNCVQDIFNVQEPSDAVNSLNVRIDIGLANPGTSPVLDTSSPASVAYSIPFIKDCGEDELCICDLVLNIQQKGDDGKQQFIVSSKNKRLTFNVKLRNKKENAYNTRIQATFSDNLFFASSSLPSDGTEVSCQTGTSQTTVICQISYPVFRTGQQVSFDISFDFNLKNLQNMAVLSFHALSESKEEQEPDNQISLSIPLRYDAEIHFTRLANINFYEVYSGHNIPSTVNNFEDIGPMFNFSVKVTTGSIPVKMASVKIHLPELTSKDNALMYITAVDTDQARGVTCQVQINPLQIGIRPYSASFKKENLRAVKELNCKNAKCSTITCKLEDLMLKGEYFVNVSTRIWNSTFAVSTFQTVQLFAEAEINVHNTDLFIIGENTLTIPVTIIKPDEKAEIPIGVVIGSILAGLLLLLALVAVLWKLGFFKRQYEKMTQDIEDIDEITELTKDKD", "length": 1124, "header": "tr|A0A8V0YNQ2-1|A0A8V0YNQ2_CHICK Computationally mapped isoform of Integrin alpha-2 OS=Gallus gallus OX=9031 GN=ITGA2 PE=1 SV=1 CANONICAL=A0A8V0YFV5-1" }, "locus": { "chromosome": "Z", "start_pos": 16464167, "end_pos": 16425472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030610.1", "url": "https://www.ensembl.org/id/ENSGALT00010030610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017756.1", "url": "https://www.ensembl.org/id/ENSGALP00010017756.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857227", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857227", "resource": "KEGG Pathway" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-3000170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000170", "resource": "Reactome", "description": "Syndecan interactions" }, { "id": "R-GGA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K470-1", "protein_name": "Integrin alpha-2", "gene_name": "Itga2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPGQAGGALLLQLLLLTQGLLSCLAYNVGLPGAKIFSGSSSEQFGYSVQQLTTPQGNWLLVGSPWSGFPDNRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQSLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLEKFVQGLDIGPKKTQVALIQYANDPRVVFNLTTYKNKEDMVQATSETRQYGGDLTNTFKAIQFARDIAYLPESGGRPGATKVMVVVTDGESHDGSKLQTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEHIFSIEGTVQGGDNFQMEMAQVGFSADYSPQNDILMLGAVGAFDWSGTVVQETSYEHLIFPKQAFDQVLQDRNHSSFLGYSVAAISTENGVHFVAGAPRANYTGQIVLYSVNKHGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMNDLKKEEGKVYLFTITKGVLNQHQFLEGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSDGAFKSHLQFFGRSLDGYGDLNGDSITDVSIGALGQVVQLWSQSVADVATEASFTPDKIILLNKEAKITLKLCFRAKFRPPGQNHQVAILFNMTLDADQYSSRVTSRGIFRENSERFLQKTMVVSEVENCSEYHISIQKPSDVVNPLDLRVDISLEKPGTSPALEAYSETVKVFSIPFYKECGSDGICISDLILDVRQLPALRNQPFIVSNQNKRLTFSVTLKNRGESAYNTAVLAEFSENLFFASFSMPVDGTEVTCQIGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQAAINFQAFSESQETNKADNSVSLIVPLLYDAELHLTRSTNINFYEISSDENAPSVINSVEDIGPEFIFSLKITAGSAPVSMASVTIHIPLHTKEKNPLLYLTGIQTDKAGDISCRAEINPLNLPHTASPVSFKSENFRHMKELDCKTTSCSNVSCWLKDLHMKAEYFINVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMVAGLWKLGFFKRQYKKMGQNPDETDETTELNS", "length": 1178 }, "evidence": [ { "id": "A0A8V0YFV5", "url": "https://omabrowser.org/oma/group/A0A8V0YFV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MBA3-1", "protein_name": "Integrin alpha-2", "gene_name": "ITGA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPGRTGGTPLQLVLVFSQGILNCCVAYNVGLPKAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPKNRMGDVYKCPVDLSTTTCEKLNLQTSTSMSNVTEMKTNMSLGLTLTRNVGTGGFLTCGPLWAQQCGSQYYTTGVCSDVSPDFQLRTSFAPAVQTCPSFIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQMGLIQYANNPRVVFNLNTFKSKDEMIKATSQTFQYGGDLTNTFKAIQYARDTAYSTAAGGRPGATKVMVVVTDGESHDGSKLKAVIDQCNKDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERHFFNVSDEADLLEKAGTIGEQIFSIEGTVQGGDNFQMEMSQVGFSAEYSPQNNILMLGAVGAYDWSGTVVQKTPHGHLIFSKQAFEQILQDRNHSSYLGYSVASISTGNSVHFVAGAPRANYTGQIVLYSVNENGNVTVIQSHRGDQIGSYFGSVLCAVDVNKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFLEGPKGLENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGMIRLRYSQKILGSDRAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQSIADVSVDASFTPKKITLLNKNAEIKLKLCFSAKFRPTNQNNQVAIVYNITIDEDQFSSRVISRGLFKENNERCLQKTMIVSQAQRCSEYIIHIQEPSDIISPLNLCMNISLENPGTNPALEAYSETVKVFSIPFHKDCGDDGVCISDLVLNVQQLPATQQQPFIVSNQNKRLTFSVQLKNKKESAYNTEIVVDFSENLFFASWSMPVDGTEVTCQIASSQKSVTCNVGYPALKSKQQVTFTINFDFNLQNLQNQASISFRALSESQEENMADNSVNLKLSLLYDAEIHITRSTNINFYEVSLDGNVSSVVHSFEDIGPKFIFSIKVTTGSVPVSMASVIIHIPQYTKDKNPLMYLTGVHTDQAGDISCEAEINPLKIGQTSSSVSFKSENFRHIKELNCRTASCSNIMCWLRDLQVKGEYFLNVSTRIWNGTFAASTFQTVQLTAAAEIDTYNPQIYVIEENTVTIPLTIMKPHEKVEVPTGVIVGSVIAGILLLLALVAILWKLGFFKRKYEKMAKNPDETDETTELNS", "length": 1179 }, "evidence": [ { "id": "A0A8V0YFV5", "url": "https://omabrowser.org/oma/group/A0A8V0YFV5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SMF4-1", "protein_name": "Integrin alpha-2", "gene_name": "ITGA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPRPTSGARLRLLLMLTQGILNCCVAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPIDPSTTTCEKLNLQTSTSISNVTEMKTNMSLGLTLTRNAGTGGFLTCGPLWAQQCGSQYYTTGVCSDVSPDFQLLTSFSPAVQACPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIPTKTQVGLIQYANNPRVVFNLNTFKTKAEMVEATSHTTQYGGDLTNTFKAIQYARDSAYSAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDQCNNDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEADLLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYAPQNDVLMLGAVGAYDWSGTVVQQTPHGHLIFPKQAFDQILQDRNHSSYLGYSVASISTGKSIHFVAGAPRANYTGQIVLYSVNEDGNVTVIQSHRGDQIGSYFGSVLCAVDVDKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGVLNWHQFLEGPEGVENARFGSAIAALADINMDGFNDVIVGSPLENQNSGAVYIYNGHEGTIRLRYSQKILGSDGAFRSRLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQTIADVSVDASFTPEKIILLNKNAELNLKLCFSAKFRPTDPNNQVAIIYNITIDADQYSSRVTSRGLFKENNERCLQKTMIVKQAQSCSEHIIHIQKPSDVVNSLDLCVNISLENPGTSPALEAYSESAKVFSIPFYKDCGDDGICISDLVLDVQQLPATQQQPFIVSNQNKRLTFSVTLKNKKESAYNTGIVIAFSENLFFASWSMPVDGTEVTCQIPSSQKSVTCDVGYPALKREEQVTFTINFDFNLQNLQNRASVSFQALSESNEENKADNSVSFNFSLLYDAEIHITRFTNINFYEVSSDGNIPSTVHSFEDIGPKFTFSIKVTTGSVPVSMASVSIHIPQYTKGKNPLMYVTGVHTDQVGDISCNAEINPLKIGQTSSSLSFKSENFRHIKELNCRTAACSNITCWLKDLQVKGEYFLNVSTRIWNGTFATSTFQTVQLTAAAEIDTYNPQIYVIEENTVMIPITIMKPHEKAEVPTGVIIGSVIAGILLLLALVAVLWKLGFFKRKYEKMTKNPDEIDETTELNS", "length": 1178 }, "evidence": [ { "id": "A0A8V0YFV5", "url": "https://omabrowser.org/oma/group/A0A8V0YFV5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P17301-1", "protein_name": "Integrin alpha-2", "gene_name": "ITGA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS", "length": 1181 }, "evidence": [ { "id": "A0A8V0YFV5", "url": "https://omabrowser.org/oma/group/A0A8V0YFV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62469-1", "protein_name": "Integrin alpha-2", "gene_name": "Itga2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPGQAGGALLLRLLMLVQGILNCLAYNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWLLVGSPWSGFPENRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMAQVGFSADYAPQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQAFDQVLQDRNHSSFLGYSVAAISTEDGVHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKITLLNKDAKITLKLCFRAEFRPAGQNNQVAILFNMTLDADGHSSRVTSRGVFRENSERFLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSIPFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLAEFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQAAINFQAFSESQETNKADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKSVEDIGPKFIFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAEINPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMTAGLWKLGFFKRQYKKMGQNPDEMDETTELNS", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFW4-1", "uniprot_ac": "A0A8V0YFW4", "uniprot_id": "A0A8V0YFW4_CHICK", "mass": { "chemical_mass": 22654.0, "monoisotopic_mass": 22654.0 }, "refseq": { "ac": "XP_015149337", "name": "ADP-ribosylation factor-like protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149337" }, "gene_names": [ { "name": "ARL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ] }, { "name": "ARL2", "type": "synonym", "evidence": [ { "id": "XP_015149337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149337" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015149337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149337" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149337.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769546", "url": "https://www.ncbi.nlm.nih.gov/gene/769546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFW4", "url": "https://www.orthodb.org/?gene=A0A8V0YFW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45697", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45697", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSRAPSSPLQNEGALQQPSTLQDSPSPPHPRGLLSVIQRLRGSPGQELRIVLLGLDNAGKTTLLKRLASEEVSTITPTQGFNIKSVHSHGFKLNIWDIGGQRAVRPYWRKYLGSTDLLIYVIDSADQKRFEETGQELAELTEEESLMGVPLLVFANKQDLVTAAPAAEIAEGLSLHTYRDREWQIQACSALSGEGVQPSLPLRME", "length": 206, "header": "tr|A0A8V0YFW4-1|A0A8V0YFW4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 3 OS=Gallus gallus OX=9031 GN=ARL2 PE=3 SV=1 CANONICAL=A0A8V0YFW4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4/entry", "sequence": { "sequence": "MDSRAPSSPLQNEGALQQPSTLQDSPSPPHPRGLLSVIQRLRGSPGQELRIVLLGLDNAGKTTLLKRLASEEVSTITPTQGFNIKSVHSHGFKLNIWDIGGQRAVRPYWRKYLGSTDLLIYVIDSADQKRFEETGQELAELTEEESLMGVPLLVFANKQDLVTAAPAAEIAEGLSLHTYRDREWQIQACSALSGEGVQPSLPLRME", "length": 206, "header": "tr|A0A8V0YFW4-1|A0A8V0YFW4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 3 OS=Gallus gallus OX=9031 GN=ARL2 PE=3 SV=1 CANONICAL=A0A8V0YFW4-1" }, "locus": { "chromosome": "13", "start_pos": 9719685, "end_pos": 9718175, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028865.1", "url": "https://www.ensembl.org/id/ENSGALT00010028865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016624.1", "url": "https://www.ensembl.org/id/ENSGALP00010016624.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0YFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 62, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 62, "end_pos": 62, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW4" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 79, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 79, "end_pos": 79, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFX9-1", "uniprot_ac": "A0A8V0YFX9", "uniprot_id": "A0A8V0YFX9_CHICK", "mass": { "chemical_mass": 118882.0, "monoisotopic_mass": 118882.0 }, "refseq": {}, "gene_names": [ { "name": "LOC427010", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ] } ], "protein_names": [ { "name": "Zinc finger RNA-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427010", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427010", "url": "https://www.ncbi.nlm.nih.gov/gene/427010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX9", "url": "https://www.orthodb.org/?gene=A0A8V0YFX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFY9", "url": "https://www.orthodb.org/?gene=A0A8V0YFY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG05", "url": "https://www.orthodb.org/?gene=A0A8V0YG05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI38", "url": "https://www.orthodb.org/?gene=A0A8V0YI38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANCQKGERRNMASATCHVGLHTAAFHLRCFPTIQHDPSVNRAYFISFSGSSLYGGASLACNSTSPGDIPNFLLSGQSMITSRIPGRLSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHAATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAESYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTGVTYSGTSYSGYEAAVYSAASSYYQQQQQQKQAVAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKETALKASQNTNNGSTSARGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVTQATSSASTSASKPAASASNVATSSSTVNSVASSAVKILTPVGNTLLNMASNNKTSSITANIAVKKISTPKINFVGKYRSGNKLQTTGSKLEETKSAESVKTTPVATIQTQEVKPDTATEPVTPTTIAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQYHWDDRRRIPDGGYPHGPPGPLGLLGVRPGMTPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDNMTEHEKNKSKEGDDKKDSSKDRALKGVLRVGVLAKGLLLRGDKNVNLVLLCAEKPSKTLLSHIVESLPKQLAVISPEKYDIKCAVPEAAIILNSCVEPKMQVTITLTSPVIREENMRDGDITSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSATGPQSPGDALRRVFECISSGIILKGGPGILDPCEKDPFDTLAVMTDQQREDITSSAQVRECTHKVNLTVLIALDIYLPSCNKVNTVICAKSSS", "length": 1094, "header": "tr|A0A8V0YFX9-1|A0A8V0YFX9_CHICK Isoform 1 of Zinc finger RNA-binding protein OS=Gallus gallus OX=9031 GN=LOC427010 PE=4 SV=1 CANONICAL=A0A8V0YFX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9/entry", "sequence": { "sequence": "MANCQKGERRNMASATCHVGLHTAAFHLRCFPTIQHDPSVNRAYFISFSGSSLYGGASLACNSTSPGDIPNFLLSGQSMITSRIPGRLSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHAATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAESYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTGVTYSGTSYSGYEAAVYSAASSYYQQQQQQKQAVAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKETALKASQNTNNGSTSARGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVTQATSSASTSASKPAASASNVATSSSTVNSVASSAVKILTPVGNTLLNMASNNKTSSITANIAVKKISTPKINFVGKYRSGNKLQTTGSKLEETKSAESVKTTPVATIQTQEVKPDTATEPVTPTTIAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQYHWDDRRRIPDGGYPHGPPGPLGLLGVRPGMTPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDNMTEHEKNKSKEGDDKKDSSKDRALKGVLRVGVLAKGLLLRGDKNVNLVLLCAEKPSKTLLSHIVESLPKQLAVISPEKYDIKCAVPEAAIILNSCVEPKMQVTITLTSPVIREENMRDGDITSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSATGPQSPGDALRRVFECISSGIILKGGPGILDPCEKDPFDTLAVMTDQQREDITSSAQVRECTHKVNLTVLIALDIYLPSCNKVNTVICAKSSS", "length": 1094, "header": "tr|A0A8V0YFX9-1|A0A8V0YFX9_CHICK Isoform 1 of Zinc finger RNA-binding protein OS=Gallus gallus OX=9031 GN=LOC427010 PE=4 SV=1 CANONICAL=A0A8V0YFX9-1" }, "locus": { "chromosome": "W", "start_pos": 5732110, "end_pos": 5688844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029997.1", "url": "https://www.ensembl.org/id/ENSGALT00010029997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017434.1", "url": "https://www.ensembl.org/id/ENSGALP00010017434.1" } ] } }, { "isoform_ac": "A0A8V0YFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY9/entry", "sequence": { "sequence": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHAATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAESYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTGVTYSGTSYSGYEAAVYSAASSYYQQQQQQKQAVAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKETALKASQNTNNGSTSARGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVTQATSSASTSASKPAASASNVATSSSTVNSVASSAVKILTPVGNTLLNMASNNKTSSITANIAVKKISTPKINFVGGNKLQTTGSKLEETKSAESVKTTPVATIQTQEVKPDTATEPVTPTTIAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQYHWDDRRRIPDGGYPHGPPGPLGLLGVRPGMTPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDNMTEHEKNKSKEGDDKKDSSKDRALKGVLRVGVLAKGLLLRGDKNVNLVLLCAEKPSKTLLSHIVESLPKQLAVISPEKYDIKCAVPEAAIILNSCVEPKMQVTITLTSPVIREENMRDGG", "length": 872, "header": "tr|A0A8V0YFY9-1|A0A8V0YFX9_CHICK Computationally mapped isoform of Zinc finger RNA-binding protein OS=Gallus gallus OX=9031 GN=LOC427010 PE=4 SV=1 CANONICAL=A0A8V0YFX9-1" }, "locus": { "chromosome": "W", "start_pos": 5793271, "end_pos": 5696017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030007.1", "url": "https://www.ensembl.org/id/ENSGALT00010030007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017444.1", "url": "https://www.ensembl.org/id/ENSGALP00010017444.1" } ] } }, { "isoform_ac": "A0A8V0YG05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG05/entry", "sequence": { "sequence": 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"length": 1050, "header": "tr|A0A8V0YG05-1|A0A8V0YG05_CHICK Computationally mapped isoform of Zinc finger RNA-binding protein OS=Gallus gallus OX=9031 GN=LOC427010 PE=4 SV=1 CANONICAL=A0A8V0YFX9-1" }, "locus": { "chromosome": "W", "start_pos": 5793271, "end_pos": 5688996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030043.1", "url": "https://www.ensembl.org/id/ENSGALT00010030043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017459.1", "url": "https://www.ensembl.org/id/ENSGALP00010017459.1" } ] } }, { "isoform_ac": "A0A8V0YI38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI38/entry", "sequence": { "sequence": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHAATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAESYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTGVTYSGTSYSGYEAAVYSAASSYYQQQQQQKQAVAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKETALKASQNTNNGSTSARGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVTQATSSASTSASKPAASASNVATSSSTVNSVASSAVKILTPVGNTLLNMASNNKTSSITANIAVKKISTPKINFVGKYRSGNKLQTTGSKLEETKSAESVKTTPVATIQTQEVKPDTATEPVTPTTIAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQYHWDDRRRIPDGGYPHGPPGPLGLLGVRPGMTPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDNMTEHEKNKSKEGDDKKDSSKDRALKGVLRVGVLAKGLLLRGDKNVNLVLLCAEKPSKTLLSHIVESLPKQLAVISPEKYDIKCAVPEAAIILNSCVEPKMQVTITLTSPVIREENMRDGDITSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSATGPQSPGDALRRVFECISSGIILKGGPGILDPCEKDPFDTLAVMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMNQRFNTHNNRKRRRDSDGVDGFEAEGKKDKKDYDNF", "length": 1069, "header": "tr|A0A8V0YI38-1|A0A8V0YI38_CHICK Computationally mapped isoform of Zinc finger RNA-binding protein OS=Gallus gallus OX=9031 GN=LOC427010 PE=4 SV=1 CANONICAL=A0A8V0YFX9-1" }, "locus": { "chromosome": "W", "start_pos": 5793271, "end_pos": 5688446, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030056.1", "url": "https://www.ensembl.org/id/ENSGALT00010030056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017465.1", "url": "https://www.ensembl.org/id/ENSGALP00010017465.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX9" }, { "id": "PS51703", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51703" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DZF", "eco_id": "ECO_0000259", "start_pos": 746, "end_pos": 1094, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 811, "end_pos": 813 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFY0-1", "uniprot_ac": "A0A8V0YFY0", "uniprot_id": "A0A8V0YFY0_CHICK", "mass": { "chemical_mass": 13240.0, "monoisotopic_mass": 13240.0 }, "refseq": { "ac": "XP_046760254", "name": "spexin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760254" }, "gene_names": [ { "name": "SPX", "type": "recommended", "evidence": [ { "id": "A0A8V0YFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0" } ] }, { "name": "SPX", "type": "synonym", "evidence": [ { "id": "XP_046760254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760254" } ] } ], "protein_names": [ { "name": "Spexin hormone", "type": "synonym", "evidence": [ { "id": "A0A8V0YFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0/entry#names_and_taxonomy" } ] }, { "name": "spexin", "type": "synonym", "evidence": [ { "id": "XP_046760254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760254" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046760254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPX", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0", "locus": { "chromosome": "1", "start_pos": 67192484, "end_pos": 67196777, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013963", "url": "https://www.ensembl.org/id/ENSGALG00010013963" } ] } } ], "crossref": [ { "id": "A0A8V0YFY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "107053973", "url": "https://www.ncbi.nlm.nih.gov/gene/107053973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107053973", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEVYIQE", "url": "https://omabrowser.org/oma/group/DEVYIQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFY0", "url": "https://www.orthodb.org/?gene=A0A8V0YFY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28590:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28590:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046760254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046760254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLRKLTASAMALFLAMSFLSFSRSAPQAHFQRRNWTPQAMLYLKGAQGRRFISDESQRKDLYGRMQLETRSQNTNPLSLSEAAALLLSSLWKAQEVEEENSDHPGYLMDNLSNR", "length": 116, "header": "tr|A0A8V0YFY0-1|A0A8V0YFY0_CHICK Isoform 1 of Spexin hormone OS=Gallus gallus OX=9031 GN=SPX PE=3 SV=1 CANONICAL=A0A8V0YFY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0/entry", "sequence": { "sequence": "MKGLRKLTASAMALFLAMSFLSFSRSAPQAHFQRRNWTPQAMLYLKGAQGRRFISDESQRKDLYGRMQLETRSQNTNPLSLSEAAALLLSSLWKAQEVEEENSDHPGYLMDNLSNR", "length": 116, "header": "tr|A0A8V0YFY0-1|A0A8V0YFY0_CHICK Isoform 1 of Spexin hormone OS=Gallus gallus OX=9031 GN=SPX PE=3 SV=1 CANONICAL=A0A8V0YFY0-1" }, "locus": { "chromosome": "1", "start_pos": 67196720, "end_pos": 67192643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033488.1", "url": "https://www.ensembl.org/id/ENSGALT00010033488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019751.1", "url": "https://www.ensembl.org/id/ENSGALP00010019751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107053973", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053973", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z752-1", "protein_name": "Spexin", "gene_name": "Spx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGPSVLAVTAVVLLLVLSALENSSGAPQRLSEKRNWTPQAMLYLKGAQGRRFLSDQSRRKELADRPPPERRNPDLELLTLPEAAALFLASLEKSQKDEGGNFDKSELLEDRLFNW", "length": 116 }, "evidence": [ { "id": "A0A8V0YFY0", "url": "https://omabrowser.org/oma/group/A0A8V0YFY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QQI2-1", "protein_name": "Spexin prohormone 1", "gene_name": "spx", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDLRTLAAYALALLLLATFVSHSWSAPKGSFQRRNWTPQAMLYLKGTQGRRFVSEDRNEGDLYDTIRLESRSQNTENLSISKAAAFLLNILQQARDEDEPY", "length": 102 }, "evidence": [ { "id": "A0A8V0YFY0", "url": "https://omabrowser.org/oma/group/A0A8V0YFY0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R8L2-1", "protein_name": "Spexin", "gene_name": "SPX", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGPSILAVAALALLLVLSVLENSSGAPQRLSEKRNWTPQAMLYLKGAQGHRFISDQSRRKELADRPPPERRNPNLQLLTLPEAAALFLASLEKPQKDEGGDFDKSKLLEDRRFYW", "length": 116 }, "evidence": [ { "id": "A0A8V0YFY0", "url": "https://omabrowser.org/oma/group/A0A8V0YFY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VC44-1", "protein_name": "Spexin", "gene_name": "SPX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKGFKSLVVMTLTLFLVFSFMGNCNSAPQRLFERRNWTPQAMLYLKGAQGRRFLSDQSRRKDLSDRPPLERRSPNSQQLTLPEAAAVLLAFLQKPQEAGDENLDQTRFLEDSLLNW", "length": 116 }, "evidence": [ { "id": "A0A8V0YFY0", "url": "https://omabrowser.org/oma/group/A0A8V0YFY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BT56-1", "protein_name": 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granule", "id": "GO:0031045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of gastro-intestinal system smooth muscle contraction", "id": "GO:1904306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YFZ0-1", "uniprot_ac": "A0A8V0YFZ0", "uniprot_id": "A0A8V0YFZ0_CHICK", "mass": { "chemical_mass": 60053.0, "monoisotopic_mass": 60053.0 }, "refseq": {}, "gene_names": [ { "name": "SLC2A2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ] } ], "protein_names": [ { "name": "Solute carrier family 2, facilitated glucose transporter member 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0/entry#names_and_taxonomy" } ] }, { "name": "Glucose transporter type 2, liver", "type": "synonym", "evidence": [ { "id": "A0A8V0YFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC2A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0", "locus": { "chromosome": "9", "start_pos": 19416886, "end_pos": 19407671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013965", "url": "https://www.ensembl.org/id/ENSGALG00010013965" } ] } } ], "crossref": [ { "id": "A0A8V0YFZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17431", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17431", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YFZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU53", "url": "https://www.orthodb.org/?gene=A0A8V0YU53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU59", "url": "https://www.orthodb.org/?gene=A0A8V0YU59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8981373", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8981373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "34915", "url": "https://www.rhea-db.org/rhea/34915", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60368", "url": "https://www.rhea-db.org/rhea/60368", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60372", "url": "https://www.rhea-db.org/rhea/60372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60376", "url": "https://www.rhea-db.org/rhea/60376", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60380", "url": "https://www.rhea-db.org/rhea/60380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTPGYICIRKAGAAQHGVGRRMDGKSKMQAEKHLTGTLVLSVFTAVLGFFQYGYSLGVINAPQKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFERAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEA", "length": 555, "header": "tr|A0A8V0YFZ0-1|A0A8V0YFZ0_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 2 OS=Gallus gallus OX=9031 GN=SLC2A2 PE=3 SV=1 CANONICAL=A0A8V0YFZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0/entry", "sequence": { "sequence": "MQTPGYICIRKAGAAQHGVGRRMDGKSKMQAEKHLTGTLVLSVFTAVLGFFQYGYSLGVINAPQKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFERAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEA", "length": 555, "header": "tr|A0A8V0YFZ0-1|A0A8V0YFZ0_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 2 OS=Gallus gallus OX=9031 GN=SLC2A2 PE=3 SV=1 CANONICAL=A0A8V0YFZ0-1" }, "locus": { "chromosome": "9", "start_pos": 19415070, "end_pos": 19407874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033506.1", "url": "https://www.ensembl.org/id/ENSGALT00010033506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019761.1", "url": "https://www.ensembl.org/id/ENSGALP00010019761.1" } ] } }, { "isoform_ac": "A0A8V0YU53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU53/entry", "sequence": { "sequence": "MDGKSKMQAEKHLTGTLVLSVFTAVLGFFQYGYSLGVINAPQKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFERAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEGCRRKR", "length": 538, "header": "tr|A0A8V0YU53-1|A0A8V0YFZ0_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 2 OS=Gallus gallus OX=9031 GN=SLC2A2 PE=3 SV=1 CANONICAL=A0A8V0YFZ0-1" }, "locus": { "chromosome": "9", "start_pos": 19415118, "end_pos": 19408382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033491.1", "url": "https://www.ensembl.org/id/ENSGALT00010033491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019752.1", "url": "https://www.ensembl.org/id/ENSGALP00010019752.1" } ] } }, { "isoform_ac": "A0A8V0YU59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU59/entry", "sequence": { "sequence": "MDGKSKMQAEKVIEAHYGRMLGAIPMVRHATNTSRDNATITVTIPGTEAWGSSEGTLAPSAGFEDPTVSPHILTMYWSLSVSMFAVGGMVSSFTVGWIGDRLGRVKAMLVVNVLSIAGNLLMGLAKMGPSHILIIAGRAITGLYCGLSSGLVPMYVSEVSPTALRGALGTLHQLAIVTGILISQVLGLDFLLGNDELWPLLLGLSGVAALLQFFLLLLCPESPRYLYIKLGKVEEAKKSLKRLRGNCDPMKEIAEMEKEKQEAASEKRVSIGQLFSSSKYRQAVIVALMVQISQQFSGINAIFYYSTNIFERAGVGQPVYATIGVGVVNTVFTVISVFLVEKAGRRSLFLAGLMGMLISAVAMTVGLVLLSQFAWMSYVSMVAIFLFVIFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFCNWACNFIVGMCFQYIADLCGPYVFVVFAVLLLVFFLFAYLKVPETKGKSFEEIAAAFRRKKLPAKSMTELEDLRGGEEA", "length": 501, "header": "tr|A0A8V0YU59-1|A0A8V0YFZ0_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 2 OS=Gallus gallus OX=9031 GN=SLC2A2 PE=3 SV=1 CANONICAL=A0A8V0YFZ0-1" }, "locus": { "chromosome": "9", "start_pos": 19415070, "end_pos": 19408382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033500.1", "url": "https://www.ensembl.org/id/ENSGALT00010033500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019757.1", "url": "https://www.ensembl.org/id/ENSGALP00010019757.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" }, { "id": "R-GGA-422356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" }, { "id": "R-GGA-8981373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8981373", "resource": "Reactome", "description": "Intestinal hexose absorption" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "dehydroascorbic acid transport", "id": "GO:0070837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ], "pmid": "" }, { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "dehydroascorbic acid transmembrane transporter activity", "id": "GO:0033300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ0" } ], "pmid": 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"annotation": "Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03#function" }, { "database": "UniProtKB", "id": "ARBA00056513", "url": "https://www.uniprot.org/uniprotkb/ARBA00056513#function" }, { "database": "UniProtKB", "id": "A0A8V0YG08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG08#function" }, { "database": "UniProtKB", "id": "A0A8V0YH18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH18#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DECR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03", "locus": { "chromosome": "2", "start_pos": 123997304, "end_pos": 123980023, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012812", "url": "https://www.ensembl.org/id/ENSGALG00010012812" } ] } } ], "crossref": [ { "id": "A0A8V0YG03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG03", "url": "https://www.orthodb.org/?gene=A0A8V0YG03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG08", "url": "https://www.orthodb.org/?gene=A0A8V0YG08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH18", "url": "https://www.orthodb.org/?gene=A0A8V0YH18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43658:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43658:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "44912", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8V0YH18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAMIGRGALRGNISVRFPGTRRVKGRSRATRALWGRAFLGKASPGEPFVFFSCGSNVLLQESKVPQAAFFSPLQKVMLPPNSFQGKVAFVTGGGTGIGKGITTALSSLGATCVIASRKLDVLKGTAEEISSKTGNKVHAIQCDVRDPASVKNAVAQLIQVAGHPNVVINNAAGNFISPSERLSPNAWKTITDIVLNGSAFVTLEIGKELIKVQKGAAFLCITTIYAESGSGFVMPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGVFEKKMIERIPCGRLGTVEEIANLAAYLCSDYASWINGAVIRMDGGEYVFMAGEFNHLKEVTKEQWEVMEAMIRKTKGS", "length": 363, "header": "tr|A0A8V0YG03-1|A0A8V0YG03_CHICK Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Gallus gallus OX=9031 GN=DECR1 PE=1 SV=1 CANONICAL=A0A8V0YG03-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03/entry", "sequence": { "sequence": "MAAAMIGRGALRGNISVRFPGTRRVKGRSRATRALWGRAFLGKASPGEPFVFFSCGSNVLLQESKVPQAAFFSPLQKVMLPPNSFQGKVAFVTGGGTGIGKGITTALSSLGATCVIASRKLDVLKGTAEEISSKTGNKVHAIQCDVRDPASVKNAVAQLIQVAGHPNVVINNAAGNFISPSERLSPNAWKTITDIVLNGSAFVTLEIGKELIKVQKGAAFLCITTIYAESGSGFVMPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGVFEKKMIERIPCGRLGTVEEIANLAAYLCSDYASWINGAVIRMDGGEYVFMAGEFNHLKEVTKEQWEVMEAMIRKTKGS", "length": 363, "header": "tr|A0A8V0YG03-1|A0A8V0YG03_CHICK Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Gallus gallus OX=9031 GN=DECR1 PE=1 SV=1 CANONICAL=A0A8V0YG03-1" }, "locus": { "chromosome": "2", "start_pos": 123994905, "end_pos": 123980072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030732.1", "url": "https://www.ensembl.org/id/ENSGALT00010030732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017822.1", "url": "https://www.ensembl.org/id/ENSGALP00010017822.1" } ] } }, { "isoform_ac": "A0A8V0YG08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG08/entry", "sequence": { "sequence": "MAAAMIGRGALRGNISVRFPGTRRFFSCGSNVLLQESKVPQAAFFSPLQKVMLPPNSFQGKVAFVTGGGTGIGKGITTALSSLGATCVIASRKLDVLKGTAEEISSKTGNKVHAIQCDVRDPASVKNAVAQLIQVAGHPNVVINNAAGNFISPSERLSPNAWKTITDIVLNGSAFVTLEIGKELIKVQKGAAFLCITTIYAESGSGFVMPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGVFEKKMIERIPCGRLGTVEEIANLAAYLCSDYASWINGANGWWRICFYGRRIQSFERGYQRAVGSDGSND", "length": 327, "header": "tr|A0A8V0YG08-1|A0A8V0YG08_CHICK Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Gallus gallus OX=9031 GN=DECR1 PE=1 SV=1 CANONICAL=A0A8V0YG03-1" }, "locus": { "chromosome": "2", "start_pos": 123994886, "end_pos": 123980072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030741.1", "url": "https://www.ensembl.org/id/ENSGALT00010030741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017827.1", "url": "https://www.ensembl.org/id/ENSGALP00010017827.1" } ] } }, { "isoform_ac": "A0A8V0YH18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH18/entry", "sequence": { "sequence": "MAAAMIGRGALRGNISVRFPGTRRFFSCGSNVLLQESKVPQAAFFSPLQKVMLPPNSFQGKVAFVTGGGTGIGKGITTALSSLGATCVIASRKLDVLKGTAEEISSKTGNKVHAIQCDVRDPASVKNAVAQLIQVAGHPNVVINNAAGNFISPSERLSPNAWKTITDIVLNGSAFVTLEIGKELIKVQKGAAFLCITTIYAESGSGFVMPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGVFEKKMIERIPCGRLGTVEEIANLAAYLCSDYASWINGAVTKEQWEVMEAMIRKTKGS", "length": 315, "header": "tr|A0A8V0YH18-1|A0A8V0YH18_CHICK Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Gallus gallus OX=9031 GN=DECR1 PE=1 SV=1 CANONICAL=A0A8V0YG03-1" }, "locus": { "chromosome": "2", "start_pos": 123994905, "end_pos": 123980072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030738.1", "url": "https://www.ensembl.org/id/ENSGALT00010030738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017825.1", "url": "https://www.ensembl.org/id/ENSGALP00010017825.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-77288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77288", "resource": "Reactome", "description": "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "2,4-dienoyl-CoA reductase (NADPH) activity", "id": "GO:0008670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" }, { "name": "catalytic complex", "id": "GO:1902494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "44912", "name": "", "equation": "(2E,4E)-hexadienoyl-CoA + NADPH + H(+) = (3E)-hexenoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YG03-1" ], "evidence": [ { "id": "44912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44912" } ] }, { "id": "45912", "name": "", "equation": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YG03-1", "F1NG68-1" ], "evidence": [ { "id": "45912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45912" } ] }, { "id": "61892", "name": "", "equation": "a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YG03-1", "F1NG68-1" ], "evidence": [ { "id": "61892", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61892" } ] }, { "id": "R-GGA-109343", "name": "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-109994" ], "enzyme_list": [ "A0A8V0YG03-1" ], "evidence": [ { "id": "R-GGA-109343", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109343" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-109994", "participant_name": "3-trans-decenoyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "ZINC000096061868", "database": "ZINC", "url": "" }, { "id": "84793", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YG03", "gene_name": "DECR1", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0YG03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "A0A8V0YG03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG03" } ] } ] }, { "uniprot_ac": "F1NG68", "gene_name": "DECR2", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.1.124", "ec_name": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "1.3.1.124", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124" }, { "id": "1.3.1.124", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.1.124" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHD0-1", "uniprot_ac": "A0A8V0YHD0", "uniprot_id": "A0A8V0YHD0_CHICK", "mass": { "chemical_mass": 24567.0, "monoisotopic_mass": 24567.0 }, "refseq": { "ac": "XP_425018", "name": "glial cell line-derived neurotrophic factor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425018" }, "gene_names": [ { "name": "GDNF", "type": "recommended", "evidence": [ { "id": "A0A8V0YHD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD0" } ] }, { "name": "GDNF", "type": "synonym", "evidence": [ { "id": "XP_425018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425018" } ] } ], "protein_names": [ { "name": "Glial cell line-derived neurotrophic factor", "type": "recommended", "evidence": [ { "id": "A0A8V0YHD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD0/entry#names_and_taxonomy" } ] }, { "name": "glial cell line-derived neurotrophic factor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_425018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_425018.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GDNF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD0", "locus": { "chromosome": "Z", "start_pos": 12277498, "end_pos": 12296137, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012878", "url": "https://www.ensembl.org/id/ENSGALG00010012878" } ] } } ], "crossref": [ { "id": "A0A8V0YHD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395569", "url": "https://www.ncbi.nlm.nih.gov/gene/395569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DYSDQFD", "url": "https://omabrowser.org/oma/group/DYSDQFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGA9", "url": "https://www.orthodb.org/?gene=A0A8V0YGA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHD0", "url": "https://www.orthodb.org/?gene=A0A8V0YHD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12173:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12173:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8853659", "url": 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"eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 653, "start_aa": "Trp", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGC2-1", "uniprot_ac": "A0A8V0YGC2", "uniprot_id": "A0A8V0YGC2_CHICK", "mass": { "chemical_mass": 85667.0, "monoisotopic_mass": 85667.0 }, "refseq": { "ac": "XP_015151810", "name": "targeting protein for Xklp2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151810" }, "gene_names": [ { "name": "TPX2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ] }, { "name": "TPX2", "type": "synonym", "evidence": [ { "id": "XP_015151810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151810" } ] } ], "protein_names": [ { "name": "TPX2, microtubule nucleation factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2/entry#names_and_taxonomy" } ] }, { "name": "targeting protein for Xklp2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015151810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151810" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151810.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151810" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2", "locus": { "chromosome": "20", "start_pos": 10390131, "end_pos": 10376532, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014099", "url": "https://www.ensembl.org/id/ENSGALG00010014099" } ] } } ], "crossref": [ { "id": "A0A8V0YGC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "395081", "url": "https://www.ncbi.nlm.nih.gov/gene/395081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGC2", "url": "https://www.orthodb.org/?gene=A0A8V0YGC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUI6", "url": "https://www.orthodb.org/?gene=A0A8V0YUI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14326:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14326:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRYSFDVPNPCINFATLSDDDVHNADSWFDQQANLENIPPAENLAKVLQNSPAFSKPALVLSSVTSQGMTKSENCEEDEAEVSETDVVPQNTVGSLTSWRATAPAEAPQRAGRRPATKQRKTQQRKQPARVRVEKNDTTLANKEEAPPLKKMKISSSKEKLTDVSPKKELLHHPDLSPARGKNKLTVPSTPTMLKRTNMAGKLKSTEEQELEKMQQLQREVMELRKRNEESLKAAIAGTGQPMKRAVGQVTKPVDFHFCTENRIKQHVESQPEKEYKEVDFAAALRKHPPSPMRMPKGPTVPKPFNLSTGSKRKLEDTSSEYVSLAQQVEAFQKRTPSRYHLRSRKSDEGPAPAKPVKARLTNPKTPVLQTKHRFRPVACKSAAELEAEEIEKIQQYKFKARELDHKILEGGPILPKKPPVKELTQPIGFELEIEKRIQDRENKKQQQEEHFKFHSRPCPTKILEDVVGVPEKKVLPVTVPKSPVFASKSRTRMTSRDEEKEKEVVPVIKAHPMPHYGVPFKPKMPEQRHVEVCPFSFDSRDRERLIQKEKKIEELQKEEVPKFKALPLPYFDHVKLPEKKVKTPTQPEPFNLQIDERGAAKQQSWKQQLKEDLKKQKEAACFKARPNVVVYQEPFVPKKENKMLSESLSGSVVPENFELATEKRAKERQEFEKRLANLEARREKLQEQVRQQEEEREKEEIAKLRQELVHKANPIRRYRSVEVKPSDQPLTMPKSPNFSDRFRC", "length": 746, "header": "tr|A0A8V0YGC2-1|A0A8V0YGC2_CHICK Isoform 1 of TPX2, microtubule nucleation factor OS=Gallus gallus OX=9031 GN=TPX2 PE=1 SV=1 CANONICAL=A0A8V0YGC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2/entry", "sequence": { "sequence": "MSRYSFDVPNPCINFATLSDDDVHNADSWFDQQANLENIPPAENLAKVLQNSPAFSKPALVLSSVTSQGMTKSENCEEDEAEVSETDVVPQNTVGSLTSWRATAPAEAPQRAGRRPATKQRKTQQRKQPARVRVEKNDTTLANKEEAPPLKKMKISSSKEKLTDVSPKKELLHHPDLSPARGKNKLTVPSTPTMLKRTNMAGKLKSTEEQELEKMQQLQREVMELRKRNEESLKAAIAGTGQPMKRAVGQVTKPVDFHFCTENRIKQHVESQPEKEYKEVDFAAALRKHPPSPMRMPKGPTVPKPFNLSTGSKRKLEDTSSEYVSLAQQVEAFQKRTPSRYHLRSRKSDEGPAPAKPVKARLTNPKTPVLQTKHRFRPVACKSAAELEAEEIEKIQQYKFKARELDHKILEGGPILPKKPPVKELTQPIGFELEIEKRIQDRENKKQQQEEHFKFHSRPCPTKILEDVVGVPEKKVLPVTVPKSPVFASKSRTRMTSRDEEKEKEVVPVIKAHPMPHYGVPFKPKMPEQRHVEVCPFSFDSRDRERLIQKEKKIEELQKEEVPKFKALPLPYFDHVKLPEKKVKTPTQPEPFNLQIDERGAAKQQSWKQQLKEDLKKQKEAACFKARPNVVVYQEPFVPKKENKMLSESLSGSVVPENFELATEKRAKERQEFEKRLANLEARREKLQEQVRQQEEEREKEEIAKLRQELVHKANPIRRYRSVEVKPSDQPLTMPKSPNFSDRFRC", "length": 746, "header": "tr|A0A8V0YGC2-1|A0A8V0YGC2_CHICK Isoform 1 of TPX2, microtubule nucleation factor OS=Gallus gallus OX=9031 GN=TPX2 PE=1 SV=1 CANONICAL=A0A8V0YGC2-1" }, "locus": { "chromosome": "20", "start_pos": 10388531, "end_pos": 10380469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033851.1", "url": "https://www.ensembl.org/id/ENSGALT00010033851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019909.1", "url": "https://www.ensembl.org/id/ENSGALP00010019909.1" } ] } }, { "isoform_ac": "A0A8V0YUI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI6/entry", "sequence": { "sequence": "MSRYSFDVPNPCINFATLSDDDVHNADSWFDQQANLENIPPAENLAKVLQNSPAFSKPALVLSSVTSQGMTKSENCEEDEAEVSETDVVPQNTVGSLTSWRATAPAEAPQRAGRRPATKQRKTQQRKQPARVRVEKNDTTLANKEEAPPLKKMKISSSKEKLTDVSPKKELLHHPDLSPARGKNKLTVPSTPTMLKRTNMAGKLKSTEEQELEKMQQLQREVMELRKRNEESLKAAIAGTGQPMKRAVGQVTKPVDFHFCTENRIKQHVESQPEKEYKEVDFAAALRKHPPSPMRMPKGPTVPKPFNLSTGSKRKLEDTSSEYVSLAQQVEAFQKRTPSRYHLRSRKSDEGPAPAKPVKARLTNPKTPVLQTKHRFRPVACKSAAELEAEEIEKIQQYKFKARELDHKILEGGPILPKKPPVKELTQPIGFELEIEKRIQDRENKKQQQEEHFKFHSRPCPTKILEDVVGVPEKKVLPVTVPKSPVFASKSRTRMTSRDEEKEKEVVPVIKAHPMPHYGVPFKPKMPEQRHVEVCPFSFDSRDRERLIQKEKKIEELQKEEVPKFKALPLPYFDHVKLPEKKVKTPTQPEPFNLQIDERGAAKQQSWKQQLKEDLKKQKEAACFKARPNVVVYQEPFVPKKENKMLSVPENFELATEKRAKERQEFEKRLANLEARREKLQEQVRQQEEEREKEEIAKLRQELVHKANPIRRYRSVEVKPSDQPLTMPKSPNFSDRFRC", "length": 739, "header": "tr|A0A8V0YUI6-1|A0A8V0YGC2_CHICK Computationally mapped isoform of TPX2, microtubule nucleation factor OS=Gallus gallus OX=9031 GN=TPX2 PE=1 SV=1 CANONICAL=A0A8V0YGC2-1" }, "locus": { "chromosome": "20", "start_pos": 10388531, "end_pos": 10380469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033865.1", "url": "https://www.ensembl.org/id/ENSGALT00010033865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019915.1", "url": "https://www.ensembl.org/id/ENSGALP00010019915.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "axon hillock", "id": "GO:0043203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGC2", "database": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF12214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TPX2 central", "eco_id": "ECO_0000259", "start_pos": 361, "end_pos": 487, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 301 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 739, "end_pos": 741 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGC5-1", "uniprot_ac": "A0A8V0YGC5", "uniprot_id": "A0A8V0YGC5_CHICK", "mass": { "chemical_mass": 154808.0, "monoisotopic_mass": 154808.0 }, "refseq": { "ac": "NP_001006379", "name": "ribonuclease 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" }, "gene_names": [ { "name": "DROSHA", "type": "recommended", "evidence": [ { "id": "A0A8V0YGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ] }, { "name": "DROSHA", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] }, { "name": "RNASEN", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] } ], "protein_names": [ { "name": "Ribonuclease 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5/entry#names_and_taxonomy" } ] }, { "name": "3.1.26.3", "type": "synonym", "evidence": [ { "id": "A0A8V0YGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5/entry#names_and_taxonomy" } ] }, { "name": "Ribonuclease III", "type": "synonym", "evidence": [ { "id": "A0A8V0YGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5/entry#names_and_taxonomy" } ] }, { "name": "drosha, ribonuclease type III", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] }, { "name": "protein Drosha", "type": "synonym", "evidence": [ { "id": "A0A8V0YGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5/entry#names_and_taxonomy" } ] }, { "name": "ribonuclease 3", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] }, { "name": "ribonuclease III, nuclear", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] }, { "name": "ribonuclease type III, nuclear", "type": "synonym", "evidence": [ { "id": "NP_001006379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720721.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000040.1. On Sep 23, 2021 this sequence version replaced NP_001006379.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379" } ] }, { "annotation": "Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. Plays a role in growth homeostasis in response to autophagy in motor neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5#function" }, { "database": "UniProtKB", "id": "ARBA00055411", "url": "https://www.uniprot.org/uniprotkb/ARBA00055411#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DROSHA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5", "locus": { "chromosome": "2", "start_pos": 68971440, "end_pos": 68902443, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011033", "url": "https://www.ensembl.org/id/ENSGALG00010011033" } ] } } ], "crossref": [ { "id": "cd00593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420911", "url": "https://www.ncbi.nlm.nih.gov/gene/420911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420911", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENFTIHE", "url": "https://omabrowser.org/oma/group/ENFTIHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGC5", "url": "https://www.orthodb.org/?gene=A0A8V0YGC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11207:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11207:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFHSGRGCPRGQGGPGARTSAQTYRPQNLRQLHPQQPSVQYQYDQQAAPAATYSNPSATSYMPPRPDFVPYPPPVPPSTQNPINQCPMRPPFPNHQMRQSFPVPPCFPPAPPPVPAPSNAPVPATATGQSTFPYMMPPPAVPHPPPPPVIPQQVNYQPVYSTGYSQQSFPPPNFNSYQHNSGSFQSSTTNSSSGSSHFRHTGQYQGEKSQSDRRSPERSKHYDEHRHREHSHIHGDRHRSNNHGDRRDRGRSPDRRRQESSRHRTEYDRGRMSPHHRSYERSRERDRDRHRHRDSRRSPSPDRSYKKDYKRAGSRSPSRERKRPRWEEERERWSESQSANKEKNYTSIKDKESEENASEKNEDEDDELLKPVWVRCTHSESYYSNDPMDQVGDSTVVGTSKLRDLYEKFEEELGKRQAKAKAARPPWEPPKTKLDEDLESSSESECDSDDDSSCSSSSDSEVFDVIAEIKRKKAHPDRLHEELWYNDPGQMNDGPLCKCSAKARRTGIRHGIYPGEEPIKPCRPMTNNAGRLYHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFSHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSSYLFKDILELYDWHLKGPSVENDSVSCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCNKALVPEEEIANMLQWEELEWQKYAEECKGMIVTSPGMKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQADKQKLSQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFRDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPAPSRINHNERLEFLGDAVVEFLTSVHLYYLFPTLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDKDLRDVWLNYPLHPLQLQESNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEFAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQERETDETEEARK", "length": 1336, "header": "tr|A0A8V0YGC5-1|A0A8V0YGC5_CHICK Isoform 1 of Ribonuclease 3 OS=Gallus gallus OX=9031 GN=DROSHA PE=3 SV=1 CANONICAL=A0A8V0YGC5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5/entry", "sequence": { "sequence": "MSFHSGRGCPRGQGGPGARTSAQTYRPQNLRQLHPQQPSVQYQYDQQAAPAATYSNPSATSYMPPRPDFVPYPPPVPPSTQNPINQCPMRPPFPNHQMRQSFPVPPCFPPAPPPVPAPSNAPVPATATGQSTFPYMMPPPAVPHPPPPPVIPQQVNYQPVYSTGYSQQSFPPPNFNSYQHNSGSFQSSTTNSSSGSSHFRHTGQYQGEKSQSDRRSPERSKHYDEHRHREHSHIHGDRHRSNNHGDRRDRGRSPDRRRQESSRHRTEYDRGRMSPHHRSYERSRERDRDRHRHRDSRRSPSPDRSYKKDYKRAGSRSPSRERKRPRWEEERERWSESQSANKEKNYTSIKDKESEENASEKNEDEDDELLKPVWVRCTHSESYYSNDPMDQVGDSTVVGTSKLRDLYEKFEEELGKRQAKAKAARPPWEPPKTKLDEDLESSSESECDSDDDSSCSSSSDSEVFDVIAEIKRKKAHPDRLHEELWYNDPGQMNDGPLCKCSAKARRTGIRHGIYPGEEPIKPCRPMTNNAGRLYHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFSHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSSYLFKDILELYDWHLKGPSVENDSVSCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCNKALVPEEEIANMLQWEELEWQKYAEECKGMIVTSPGMKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQADKQKLSQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFRDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPAPSRINHNERLEFLGDAVVEFLTSVHLYYLFPTLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDKDLRDVWLNYPLHPLQLQESNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEFAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQERETDETEEARK", "length": 1336, "header": "tr|A0A8V0YGC5-1|A0A8V0YGC5_CHICK Isoform 1 of Ribonuclease 3 OS=Gallus gallus OX=9031 GN=DROSHA PE=3 SV=1 CANONICAL=A0A8V0YGC5-1" }, "locus": { "chromosome": "2", "start_pos": 68971140, "end_pos": 68904619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026441.1", "url": "https://www.ensembl.org/id/ENSGALT00010026441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015050.1", "url": "https://www.ensembl.org/id/ENSGALP00010015050.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PTR3-1", "protein_name": "Ribonuclease 3", "gene_name": "Drosha", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPTYRPQNLRLLHPQQPPAQYQYEPPSAPSSSFSNSQAPNFMPPRPDFVPYPPPVAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVSGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPNFNSFQNNSSSFPPSANNSSTPHFRHLPPYSLPKAQSERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSEYDRGRTPPPRHRSYERSRERERERHRHRENRRSPSLERAYKKEYKRSGRSYGLPVTPEPAGCTAELPGEIIKNTDSWAPPQENVNHRSPSREKKRARWEEEKDRWSDSQSSGKEKSYTSIKEKEPEEAPPEKTEEEDEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGTLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDEAEDIKK", "length": 1373 }, "evidence": [ { "id": "A0A8V0YGC5", "url": "https://omabrowser.org/oma/group/A0A8V0YGC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5HZJ0-1", "protein_name": "Ribonuclease 3", "gene_name": "Drosha", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK", "length": 1373 }, "evidence": [ { "id": "A0A8V0YGC5", "url": "https://omabrowser.org/oma/group/A0A8V0YGC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRR4-1", "protein_name": "Ribonuclease 3", "gene_name": "DROSHA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK", "length": 1374 }, "evidence": [ { "id": "A0A8V0YGC5", "url": "https://omabrowser.org/oma/group/A0A8V0YGC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "microprocessor complex", "id": "GO:0070877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "DEAD/H-box RNA helicase binding", "id": "GO:0017151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "ribonuclease III activity", "id": "GO:0004525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" }, { "name": "primary miRNA binding", "id": "GO:0070878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070878", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1146, "end_pos": 1148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"3.1.26.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.3" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1146, "end_pos": 1148 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 633, "end_pos": 635 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "negative regulation of low-density lipoprotein particle clearance", "id": "GO:0010989", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010989", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "regulation of low-density lipoprotein particle receptor catabolic process", "id": "GO:0032803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8854628", "name": "MYLIP dimer ubiquitinates VLDLR on Lys-839", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-GGA-5216079" ], "output_participant_list": [ "R-GGA-8855136" ], "enzyme_list": [ "A0A8V0YGF4-1" ], "evidence": [ { "id": "R-GGA-8854628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854628" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-5216079", "participant_name": "VLDLR [plasma membrane]", "crossref": [ { "id": "P98165", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010011837", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010016204", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010028290", "database": "ENSEMBL", "url": "" }, { "id": "P98165", "database": "PRO", "url": "" }, { "id": "NP_990560.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-8855136", "participant_name": "VLDLR [plasma membrane]", "crossref": [ { "id": "ENSGALT00010028290", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010011837", "database": "ENSEMBL", "url": "" }, { "id": "NP_990560.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010016204", "database": "ENSEMBL", "url": "" }, { "id": "P98165", "database": "UniProt", "url": "" }, { "id": "P98165", "database": "PRO", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 279, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGH8-1", "uniprot_ac": "A0A8V0YGH8", "uniprot_id": "A0A8V0YGH8_CHICK", "mass": { "chemical_mass": 42151.0, "monoisotopic_mass": 42151.0 }, "refseq": { "ac": "XP_040512102", "name": "urea transporter 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512102" }, "gene_names": [ { "name": "SLC14A2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8" } ] }, { "name": "SLC14A2", "type": "synonym", "evidence": [ { "id": "XP_040512102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512102" } ] } ], "protein_names": [ { "name": "Urea transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0YGH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8/entry#names_and_taxonomy" } ] }, { "name": "urea transporter 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040512102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512102" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC14A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8", "locus": { "chromosome": "Z", "start_pos": 2612264, "end_pos": 2628568, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012134", "url": "https://www.ensembl.org/id/ENSGALG00010012134" } ] } } ], "crossref": [ { "id": "A0A8V0YGH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "770445", "url": "https://www.ncbi.nlm.nih.gov/gene/770445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YFPEVKI", "url": "https://omabrowser.org/oma/group/YFPEVKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH8", "url": "https://www.orthodb.org/?gene=A0A8V0YGH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10464", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10464", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10464:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10464:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-549127", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040512102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "32799", "url": "https://www.rhea-db.org/rhea/32799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSTDVKIETKGERKPRKQSQLSKGGKSVCRAVGYITGDMKEFGAWLKDKPIVIQFVDWVLRGISQVMFVNNPLSGLIVVAGFLVQNPWWTLTGCLGTVVSTLTALILGQDRSAIAAGLYGYNGVLVGLLMAVFSAKGDYHWWLLLPVALVSVTCPVFTSALGSVFCKWDLPVFTLPFNLALTLYLAASGPHNLFFPTIIIQPATATPNVTWTDADMPMLLQSIPIGVGQVYGCDNPWTGGIFLLALFISSPLICLHAAIGSAVGMLAALSLATPFSTIYSGLWSYNSSLSCIAIGGMFYAFTWQTHLLAITCALFSAYLGATVTNMLSVFGVPPGTWSFCLSALTFLLMTTNHSAIYKLPLSKVTYPEANRAYYLRMKKQHTSCCDV", "length": 389, "header": "tr|A0A8V0YGH8-1|A0A8V0YGH8_CHICK Isoform 1 of Urea transporter OS=Gallus gallus OX=9031 GN=SLC14A2 PE=3 SV=1 CANONICAL=A0A8V0YGH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8/entry", "sequence": { "sequence": "MENSTDVKIETKGERKPRKQSQLSKGGKSVCRAVGYITGDMKEFGAWLKDKPIVIQFVDWVLRGISQVMFVNNPLSGLIVVAGFLVQNPWWTLTGCLGTVVSTLTALILGQDRSAIAAGLYGYNGVLVGLLMAVFSAKGDYHWWLLLPVALVSVTCPVFTSALGSVFCKWDLPVFTLPFNLALTLYLAASGPHNLFFPTIIIQPATATPNVTWTDADMPMLLQSIPIGVGQVYGCDNPWTGGIFLLALFISSPLICLHAAIGSAVGMLAALSLATPFSTIYSGLWSYNSSLSCIAIGGMFYAFTWQTHLLAITCALFSAYLGATVTNMLSVFGVPPGTWSFCLSALTFLLMTTNHSAIYKLPLSKVTYPEANRAYYLRMKKQHTSCCDV", "length": 389, "header": "tr|A0A8V0YGH8-1|A0A8V0YGH8_CHICK Isoform 1 of Urea transporter OS=Gallus gallus OX=9031 GN=SLC14A2 PE=3 SV=1 CANONICAL=A0A8V0YGH8-1" }, "locus": { "chromosome": "Z", "start_pos": 2592916, "end_pos": 2585387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029095.1", "url": "https://www.ensembl.org/id/ENSGALT00010029095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016854.1", "url": "https://www.ensembl.org/id/ENSGALP00010016854.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-549127", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "resource": "Reactome", "description": "SLC-mediated transport of organic cations" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "urea transmembrane transport", "id": "GO:0071918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071918", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "urea transmembrane transporter activity", "id": "GO:0015204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32799", "name": "", "equation": "urea(in) = urea(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32799" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGK5-1", "uniprot_ac": "A0A8V0YGK5", "uniprot_id": "A0A8V0YGK5_CHICK", "mass": { "chemical_mass": 98397.0, "monoisotopic_mass": 98397.0 }, "refseq": { "ac": "XP_040555217", "name": "exocyst complex component 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555217" }, "gene_names": [ { "name": "LOC422308", "type": "recommended", "evidence": [ { "id": "A0A8V0YGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5" } ] }, { "name": "LOC422308", "type": "synonym", "evidence": [ { "id": "XP_040555217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555217" } ] } ], "protein_names": [ { "name": "Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040555217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555217" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040555217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555217" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422308", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422308", "url": "https://www.ncbi.nlm.nih.gov/gene/422308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PCVSRFQ", "url": "https://omabrowser.org/oma/group/PCVSRFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGK5", "url": "https://www.orthodb.org/?gene=A0A8V0YGK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16092:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16092:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040555217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLWSSLEKEVFNPQNKRLLEAIHVWKTGKKKKMSILCILVDAFRPTQPFLAKVKVDRGVQYKVAYRWPLAELKLVDGKSLDQVNPDFDLQFDKIYKWTASSFDEKKTFIRCLWKLNHRFLSSAITFVNVHSCSVEGRQRPQEDRRDTAETGNQEELSAYQEMTPKEAADVLKLMEEYEPLVNNSIAFAEQLSRDLHVLDEANLRAIISSEKQVTQLMSSIDEALAEVARVEETLQVYDVLLGSVKQQMDHIHQENSLLHHITSNKAKLMDEILFLTTHLDLGKEHCEALSCADLSSPSGVEACIAAAEALSACMNIQIQSGYRKLQAVAEQLIMFETLKQNFENRFIGHITNIFERQGSAQIPALTQPVDKLSAPSHGLQHEELMPYTPLMAWLKNANPMLFCDLPKVYAQNLSRLYDREIKAFFEQAKILLVERRKGSLQEGLEKPTGMGSRQHPRWSLPVSRECQEDTPNKGNVIKQILEQVLRELRPLCIAEQLFIEKFFQLSQNSTEPQVLEEEGSTASPEDPACAKPPSQPEEQTAQLLSEIFSSLDPELRCFLDVCSKAHPFSCLQILVTLNDCIFEMWGKTSALPSSFLNTVLGNMLLLAKSSFNKCIGTLCKEIEEAKVPSKLKVGILPSVSRFEEFVNFSEAVFRTAQRRAELDKAHLRLADSVFNSINSLSSANLKVNTDMVMMENFHHVHCFLCQKKIQCLEGKKREAKQRYSEHMEKYVIGSLGQPLEKLNHFFEGVKARVAQGVKEEEISFQLAYSKQELRKVIERYPGKEVKRALETLYRKIHKYLSPEENLFPVVWHAMEQELLRQYQEFEDLIQRCYVGSGITMEFTMEDLLSYFNSITLSST", "length": 861, "header": "tr|A0A8V0YGK5-1|A0A8V0YGK5_CHICK Isoform 1 of Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422308 PE=3 SV=1 CANONICAL=A0A8V0YGK5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5/entry", "sequence": { "sequence": "MASLWSSLEKEVFNPQNKRLLEAIHVWKTGKKKKMSILCILVDAFRPTQPFLAKVKVDRGVQYKVAYRWPLAELKLVDGKSLDQVNPDFDLQFDKIYKWTASSFDEKKTFIRCLWKLNHRFLSSAITFVNVHSCSVEGRQRPQEDRRDTAETGNQEELSAYQEMTPKEAADVLKLMEEYEPLVNNSIAFAEQLSRDLHVLDEANLRAIISSEKQVTQLMSSIDEALAEVARVEETLQVYDVLLGSVKQQMDHIHQENSLLHHITSNKAKLMDEILFLTTHLDLGKEHCEALSCADLSSPSGVEACIAAAEALSACMNIQIQSGYRKLQAVAEQLIMFETLKQNFENRFIGHITNIFERQGSAQIPALTQPVDKLSAPSHGLQHEELMPYTPLMAWLKNANPMLFCDLPKVYAQNLSRLYDREIKAFFEQAKILLVERRKGSLQEGLEKPTGMGSRQHPRWSLPVSRECQEDTPNKGNVIKQILEQVLRELRPLCIAEQLFIEKFFQLSQNSTEPQVLEEEGSTASPEDPACAKPPSQPEEQTAQLLSEIFSSLDPELRCFLDVCSKAHPFSCLQILVTLNDCIFEMWGKTSALPSSFLNTVLGNMLLLAKSSFNKCIGTLCKEIEEAKVPSKLKVGILPSVSRFEEFVNFSEAVFRTAQRRAELDKAHLRLADSVFNSINSLSSANLKVNTDMVMMENFHHVHCFLCQKKIQCLEGKKREAKQRYSEHMEKYVIGSLGQPLEKLNHFFEGVKARVAQGVKEEEISFQLAYSKQELRKVIERYPGKEVKRALETLYRKIHKYLSPEENLFPVVWHAMEQELLRQYQEFEDLIQRCYVGSGITMEFTMEDLLSYFNSITLSST", "length": 861, "header": "tr|A0A8V0YGK5-1|A0A8V0YGK5_CHICK Isoform 1 of Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422308 PE=3 SV=1 CANONICAL=A0A8V0YGK5-1" }, "locus": { "chromosome": "4", "start_pos": 11324463, "end_pos": 11303927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029130.1", "url": "https://www.ensembl.org/id/ENSGALT00010029130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016887.1", "url": "https://www.ensembl.org/id/ENSGALP00010016887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9SX86-1", "protein_name": "Exocyst complex component SEC3B", "gene_name": "SEC3B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKSSADDEELRRACEAAIEGTKQSIVMSIRVAKSRGVWGKSGKLGRQMAKPRVLALSVKSKGPRKKAILRVMKYSSGGVLEPAKMYDLKHLSKVEVITSDPSGCTFTLGFDNLRSQSVAPPQWTMRNTDDRNRLLVCILNICKDVLGRLPKVVGIDIVEMALWAKDNTPVVTTQRSTEDGEPVAESVTESALKVTVEKELVSQAEEEDMEALLGTYVIGIGEAEAFSERLKRELQALEAANVHAILESEPLVDEVLNGLEAATNIVDDMDEWLGIFNIKLRHMREDIESIEIRNNKLEMQSVNNKALIEELDKVIERLRVPSEYAASLTGGSFDEADMLQNIEACEWLAKALRGLEVPNLDPIYANMRAVKEKRAELEKLKATFVRRASEFLRDYFASLVDFKFSDKSYFSQRGQLKRPDHADLRYKCRTYARLMQHLKGLNKNCLGPLRKAYCSSLNLLLRREAREFAKELRASTKVSRNPTVWLEGSTGSSQNANTDTSAVSDAYAKMLTIFIPLLVDESSFFAHFMCFEVPALAPPGGAGNDKKSQSNNDDGNDNDDLGIMDIDEADKKPGKNSPDLTALNESLQDLLDGIQEDFYAVVDWAYKIDPLRSISMHGITERYLSGQKADAAGFVRLLLGDLESRISMQFSHFVDEACHQIEKNERNVRQMGVLPYIPRFAALATRMEQYIQGQSRNLVDQAYTKFVSILFVTLEKIAQQDPKYADILLLENYAAFQTCLFDLANVVPTLAKFYDQAMEAYEQACTRHISMIIYYQFERLFLFDKKIKDLMYTITPEEIPFQLGLSKVELRKMLKSSLSGVDKSIAAMYKKLQKNLASEELLPSLWDKCKKEFLDKYESFVQLVAKVYPSENVPGVTEMRGLLASM", "length": 887 }, "evidence": [ { "id": "A0A8V0YGK5", "url": "https://omabrowser.org/oma/group/A0A8V0YGK5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK5" } ], "pmid": "" } ] }, { "name": 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The reference sequence was derived from JAENSK010000012.1. 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[ { "id": "A0A8V0YGN2", "url": "https://omabrowser.org/oma/group/A0A8V0YGN2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H9Z1-1", "protein_name": "Microsomal glutathione S-transferase 1", "gene_name": "Mgst1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADLHQLKDNEVLMAFASYATIVLTKMMFMSSATAFQRLTNKIFANPEDCAGFGKGENAKKFLRTDEKVERVRRAHLNDIENIVPFLGIGLLYSLSGPDLSTALMHFRIFVGARIYHTIAYLTPLPQPNRALAFFAGYGVTLSMAYRLLKSRLYL", "length": 155 }, "evidence": [ { "id": "A0A8V0YGN2", "url": "https://omabrowser.org/oma/group/A0A8V0YGN2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P08011-1", "protein_name": "Microsomal glutathione S-transferase 1", "gene_name": "Mgst1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20137-1", "P20135-1", "A0A8V0ZJE0-1", "Q08392-1", "Q08393-1", "A0A8V0Y5A9-1", "A0A8V0YGN2-1", "F1N9G6-1", "A0A8V1AHJ8-1", "O73888-1", "P20136-1", "P26697-1", "E1BUB6-1", "A0A1D5PN41-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-GGA-176059", "name": "GST trimers transfer GS from GSH to luminal substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y9R9-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-176059", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176059" } ] }, { "id": "R-GGA-5423653", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y9R9-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-5423653", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423653" } ] }, { "id": "R-GGA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, azurophil granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U2N5-1", "Q98932-1", "A0A1D5PVG8-1", "Q5ZHX1-1", "A0A8V1AN75-1", "A0A8V0Z1E9-1", "A0A8V0YYJ1-1", "A0A8V0ZEG9-1", "A0A3Q2UE42-1", "A0A8V0Y298-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-6798739", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798739" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PN41", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5PN41", 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"A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] } ] }, { "uniprot_ac": "A0A8V0Y5A9", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0Y5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0Y5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A9" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R9", "gene_name": "MGST3", "activity": [ { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "A0A8V0Y9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R9" } ] }, { "ec_number": "4.4.1.20", "activity": "", "evidence": [ { "id": "A0A8V0Y9R9", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233648" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8", "locus": { "chromosome": "1", "start_pos": 36571927, "end_pos": 36559786, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012738", "url": "https://www.ensembl.org/id/ENSGALG00010012738" } ] } } ], "crossref": [ { "id": "A0A8V0YGN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04123", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04123", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771383", "url": "https://www.ncbi.nlm.nih.gov/gene/771383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771383", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NDEQHRN", "url": "https://omabrowser.org/oma/group/NDEQHRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGN8", "url": "https://www.orthodb.org/?gene=A0A8V0YGN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGTGAAAGGRSFSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSVQEAETYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERARGNGSSQSGTARRGVQIIDDEPQVQSSGGCCSSG", "length": 220, "header": "tr|A0A8V0YGN8-1|A0A8V0YGN8_CHICK Isoform 1 of Ras-related protein Rab-21 OS=Gallus gallus OX=9031 GN=RAB21 PE=1 SV=1 CANONICAL=A0A8V0YGN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8/entry", "sequence": { "sequence": "MAAGTGAAAGGRSFSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSVQEAETYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERARGNGSSQSGTARRGVQIIDDEPQVQSSGGCCSSG", "length": 220, "header": "tr|A0A8V0YGN8-1|A0A8V0YGN8_CHICK Isoform 1 of Ras-related protein Rab-21 OS=Gallus gallus OX=9031 GN=RAB21 PE=1 SV=1 CANONICAL=A0A8V0YGN8-1" }, "locus": { "chromosome": "1", "start_pos": 36570567, "end_pos": 36559976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030493.1", "url": "https://www.ensembl.org/id/ENSGALT00010030493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017686.1", "url": "https://www.ensembl.org/id/ENSGALP00010017686.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771383", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4W6-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "RAB21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAGGGGAAAARAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGATRRGVQIIDDEPQAQSGGGGCCSSG", "length": 222 }, "evidence": [ { "id": "A0A8V0YGN8", "url": "https://omabrowser.org/oma/group/A0A8V0YGN8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P35282-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "Rab21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSSGGCCSSG", "length": 222 }, "evidence": [ { "id": "A0A8V0YGN8", "url": "https://omabrowser.org/oma/group/A0A8V0YGN8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q17R06-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "RAB21", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAGGGGAAAGRTYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKVDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGAARRGVQIIDDEPQAQSVGGGCCSSG", "length": 222 }, "evidence": [ { "id": "A0A8V0YGN8", "url": "https://omabrowser.org/oma/group/A0A8V0YGN8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXT5-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "Rab21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSGSGGCCSSG", "length": 223 }, "evidence": [ { "id": "A0A8V0YGN8", "url": "https://omabrowser.org/oma/group/A0A8V0YGN8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UL25-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "RAB21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG", "length": 225 }, "evidence": [ { "id": "A0A8V0YGN8", "url": "https://omabrowser.org/oma/group/A0A8V0YGN8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "cytoplasmic side of early endosome membrane", "id": "GO:0098559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "anterograde axonal transport", "id": "GO:0008089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008089", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "positive regulation of early endosome to late endosome transport", "id": "GO:2000643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-8876837", "name": "RAB21 GEFs exchange GTP for GDP on RAB21", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YGN8-1" ], "evidence": [ { "id": "R-GGA-8876837", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876837" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": 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Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.5.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGN9-1", "uniprot_ac": "A0A8V0YGN9", "uniprot_id": "A0A8V0YGN9_CHICK", "mass": { "chemical_mass": 30563.0, "monoisotopic_mass": 30563.0 }, "refseq": { "ac": "XP_422279", "name": "calcyclin-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422279" }, "gene_names": [ { "name": "CACYBP", "type": "recommended", "evidence": [ { "id": "A0A8V0YGN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9" } ] }, { "name": "CACYBP", "type": "synonym", "evidence": [ { "id": "XP_422279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422279" } ] } ], "protein_names": [ { "name": "Calcyclin-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YGN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9/entry#names_and_taxonomy" } ] }, { "name": "calcyclin-binding protein", "type": "synonym", "evidence": [ { "id": "XP_422279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422279" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422279.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422279" } ] }, { "annotation": "May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9#function" }, { "database": "UniProtKB", "id": "ARBA00025145", "url": "https://www.uniprot.org/uniprotkb/ARBA00025145#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACYBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9", "locus": { "chromosome": "8", "start_pos": 7099281, "end_pos": 7106775, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011124", "url": "https://www.ensembl.org/id/ENSGALG00010011124" } ] } } ], "crossref": [ { "id": "A0A8V0YGN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06468", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06468", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424437", "url": "https://www.ncbi.nlm.nih.gov/gene/424437", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424437", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424437", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGWDQSA", "url": "https://omabrowser.org/oma/group/YGWDQSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGN9", "url": "https://www.orthodb.org/?gene=A0A8V0YGN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13164:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13164:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPRRRRRYTSVPLRGGGAGGRKVPEGLWSCRLCSGSAAQHCAACDMAAAREELQKDLEEVKELLAKATRKRLRDVLMMEKHKLELEIKNQPLPKPKDVIEEEKSSLGGYTVKINNYGWDQSDKFIKIYVSLNGVQKLPAENVQVNFTERSFDLLVKNLNGKNYTMTFNNLLKPISVEGSSRKIKTDTVLVMCKKKREEKWECLTQVEKESKEKEKAAYDTSDPSEGLMNLLKKMYAEGDDEMKRTINKAWVESREKQSKGDIPMDI", "length": 267, "header": "tr|A0A8V0YGN9-1|A0A8V0YGN9_CHICK Isoform 1 of Calcyclin-binding protein OS=Gallus gallus OX=9031 GN=CACYBP PE=1 SV=1 CANONICAL=A0A8V0YGN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9/entry", "sequence": { "sequence": "MRPRRRRRYTSVPLRGGGAGGRKVPEGLWSCRLCSGSAAQHCAACDMAAAREELQKDLEEVKELLAKATRKRLRDVLMMEKHKLELEIKNQPLPKPKDVIEEEKSSLGGYTVKINNYGWDQSDKFIKIYVSLNGVQKLPAENVQVNFTERSFDLLVKNLNGKNYTMTFNNLLKPISVEGSSRKIKTDTVLVMCKKKREEKWECLTQVEKESKEKEKAAYDTSDPSEGLMNLLKKMYAEGDDEMKRTINKAWVESREKQSKGDIPMDI", "length": 267, "header": "tr|A0A8V0YGN9-1|A0A8V0YGN9_CHICK Isoform 1 of Calcyclin-binding protein OS=Gallus gallus OX=9031 GN=CACYBP PE=1 SV=1 CANONICAL=A0A8V0YGN9-1" }, "locus": { "chromosome": "8", "start_pos": 7106770, "end_pos": 7101521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026609.1", "url": "https://www.ensembl.org/id/ENSGALT00010026609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015167.1", "url": "https://www.ensembl.org/id/ENSGALP00010015167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424437", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S710-1", "protein_name": "Calcyclin-binding protein", "gene_name": "CACYBP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASALEELQKDLEEVKVLLEKATRKRVRDTLTTEKSKIETEIKNKMQQKSQRKAELLENEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKNYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKAENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF", "length": 230 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4I4Q9-1", "protein_name": "Calcyclin-binding protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEEVGLDLEELRQLQNIAKRPRVLNLINSEISNLEKLRDSAVSSNAKPKVPVTVPAPVSSSGKPVSSSALNYVTLGTFSWDQDNDKVKMYISLEGVDEDKVQAEFKPMSLDIKIHDVQGKNYRCAIPKLCKEIMPEKCKVLVKPKRIVITMVKSSRGNWLDIHHKEDKYCLLFVQIKPSLEKEKDPMAGIMGMMKNLYEDGDEEMKKTIAKAWTDARSGKAADPLKGL", "length": 229 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3T168-1", "protein_name": "Calcyclin-binding protein", "gene_name": "CACYBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSALEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEMKNKMQQKSQRKAELTENEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLPGVHQVPAESVQVNFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKAENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTDF", "length": 230 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CXW3-1", "protein_name": "Calcyclin-binding protein", "gene_name": "Cacybp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVLEELQKDLEEVKVLLEKSTRKRLRDTLTSEKSKIETELKNKMQQKSQKKPELDNEKPAAVVAPLTTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKNYSMIVNNLLKPISVESSSKKVKTDTVIILCRKKAENTRWDYLTQVEKECKEKEKPSYDTEADPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAREDTEF", "length": 229 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB71-1", "protein_name": "Calcyclin-binding protein", "gene_name": "CACYBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF", "length": 228 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3Y3-1", "protein_name": "Calcyclin-binding protein", "gene_name": "Dmel\\CG3226", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLEQLKSDVAELAAFLQQAKGARVKDVLTTAKAEAEREIVNLELKAKIAAERQATGSSEAKRYLHELTDYGWDQSAKFVKLFITLNGVQGCTEENVTVTYTPNSLQLHVRDLQGKDFGLTVNNLLHSIDVEKSYRKIKTDMVAIYLQKVEDKHWDVLTAIQKRLKQKKDSELSKDGDNPESALVNIMKKMYNDGDSKTKQMIAKAWTESQDKAKLGKETGGGLDSFDDL", "length": 230 }, "evidence": [ { "id": "A0A8V0YGN9", "url": "https://omabrowser.org/oma/group/A0A8V0YGN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": 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"MPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKVKEEQKPQLTQWFPFSGITELVNNVLQPQQKQQNEKEPQTKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDSHYVTLPRSWYTQSTDHHHRDASQDHTIYPLFCEDAIRLLRSRKMCRTYSEGAYYDLERRTRHERRVPNTYYDDTTYTPERWYNGASSWADHIVNGSAENYGSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERKEKKADPENGDTGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSL", "length": 1537, "header": "tr|A0A8V0YI09-1|A0A8V0YI09_CHICK Isoform 1 of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS9/entry", "sequence": { "sequence": "MSAPAGPRGGPAPPQPLPATQPEMPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKVKEEQKPQLTQWFPFSGITELVNNVLQPQQKQQNEKEPQTKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKEDKVVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDRSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERNNGDKEIEPYEGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISVFTSKMQSRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 1498, "header": "tr|A0A8V0YGS9-1|A0A8V0YI09_CHICK Computationally mapped isoform of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495709, "end_pos": 129053163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031088.1", "url": "https://www.ensembl.org/id/ENSGALT00010031088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018082.1", "url": "https://www.ensembl.org/id/ENSGALP00010018082.1" } ] } }, { "isoform_ac": "A0A8V0YGV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV3/entry", "sequence": { "sequence": "MSAPAGPRGGPAPPQPLPATQPEMPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDRNCEAADRQPYQRSRSTEQRPMLERTNSRSRSTERPDSNLIRSMPSLMTGRSAPPSPALPRSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERKEKKADPENGDTGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 1507, "header": "tr|A0A8V0YGV3-1|A0A8V0YGV3_CHICK Computationally mapped isoform of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495709, "end_pos": 129053163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031108.1", "url": "https://www.ensembl.org/id/ENSGALT00010031108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018102.1", "url": "https://www.ensembl.org/id/ENSGALP00010018102.1" } ] } }, { "isoform_ac": "A0A8V0YH14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH14/entry", "sequence": { "sequence": "MSAPAGPRGGPAPPQPLPATQPEMPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKEDKVVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDRSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERNNGDKEIEPYEEEAESSRRRNSGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISVFTSKMQSRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 1469, "header": "tr|A0A8V0YH14-1|A0A8V0YH14_CHICK Computationally mapped isoform of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495709, "end_pos": 129053163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031172.1", "url": "https://www.ensembl.org/id/ENSGALT00010031172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018157.1", "url": "https://www.ensembl.org/id/ENSGALP00010018157.1" } ] } }, { "isoform_ac": "A0A8V0YH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH41/entry", "sequence": { "sequence": "MSAPAGPRGGPAPPQPLPATQPEMPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSSQSLSRRTTPFVPRVQIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDRSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERKEKKADPENGDTGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISVFTSKMQSRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 1471, "header": "tr|A0A8V0YH41-1|A0A8V0YH41_CHICK Computationally mapped isoform of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495709, "end_pos": 129053163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031208.1", "url": "https://www.ensembl.org/id/ENSGALT00010031208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018183.1", "url": "https://www.ensembl.org/id/ENSGALP00010018183.1" } ] } }, { "isoform_ac": "A0A8V0YHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW1/entry", "sequence": { "sequence": "MSAPAGPRGGPAPPQPLPATQPEMPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKEDKVVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDRNCEAADRQPYQRSRSTEQRPMLERTNSRSRSTERPDSNLIRSMPSLMTGRSAPPSPALPRSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERNNGDKEIEPYEGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISVFTSKMQSRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 1518, "header": "tr|A0A8V0YHW1-1|A0A8V0YHW1_CHICK Computationally mapped isoform of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495709, "end_pos": 129053163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031131.1", "url": "https://www.ensembl.org/id/ENSGALT00010031131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018125.1", "url": "https://www.ensembl.org/id/ENSGALP00010018125.1" } ] } }, { "isoform_ac": "A0A8V0YI09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI09/entry", "sequence": { "sequence": "MPDLSHLTEEERKIILAVMDRQKKEEEKEQSVLKVKEEQKPQLTQWFPFSGITELVNNVLQPQQKQQNEKEPQTKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGAWFYNSGSNAPQKPDQEGIRGLRNEEAPQEKKAKLQEHLQYQGPPGDISTQVLDKNRSQGLTRQDSIKNGSGVKHQITSDTASDRKRSPSISREQNRRYDQREERDEYSQYATSDSAMPRSPSDYSDRRSQRGPQLYEEPELGDYRDSNRRSRRRSKEYPVEEEDAQNREEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANTELEDSRISMLRMERPSRQRSVSERRAAMENQRSYSMERTREAQGPSPNRQRTTNHSPPTPRRSPIPLERPDMRRSDSLRKQHHLDPNSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKTKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVSEKGDMDYNWLDHTSWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWYDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYLPRRQLHGESPTRRLQRSKRISDSEVSDYDCDDGIGVVSDYRHNGRDLQSSTLSVPEQVMSSNHCSRSGSPHRGDSIGRTRSWSPSVPPPQSRNVDQGPRGTRSTAAHYNTLNRMERHRVIDDHYSPDRDSHYVTLPRSWYTQSTDHHHRDASQDHTIYPLFCEDAIRLLRSRKMCRTYSEGAYYDLERRTRHERRVPNTYYDDTTYTPERWYNGASSWADHIVNGSAENYGSHPRTGSVQTSPSSTPVVGRRGRQLPQLPPKGTLERKEKKADPENGDTGSMDIEERNRQMKMSKYKQVAGSDSRLEQDYHSKYRSGRDAQRGSDNVSNKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNKKISRQMGASGKNMTKSTSIGGDMYTLEKNDGSQSDTAVGTVGGGSKKRRSSIGAKMVAIVGLSRKSRSTSQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSL", "length": 1537, "header": "tr|A0A8V0YI09-1|A0A8V0YI09_CHICK Isoform 1 of Regulating synaptic membrane exocytosis 2 OS=Gallus gallus OX=9031 GN=RIMS2 PE=4 SV=1 CANONICAL=A0A8V0YI09-1" }, "locus": { "chromosome": "2", "start_pos": 129495625, "end_pos": 129053232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031198.1", "url": "https://www.ensembl.org/id/ENSGALT00010031198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018176.1", "url": "https://www.ensembl.org/id/ENSGALP00010018176.1" } ] } }, { "isoform_ac": "A0A8V0YPJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ8/entry", "sequence": { "sequence": "MGRQTAAGGRSMQRSQSRSSLSASFEALAVYFPCMNSLEEEDGEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLAADSQFSDFLDGLGPAQLVGRQTLATPSMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLENGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELDLSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYARS", "length": 281, "header": 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"https://www.uniprot.org/uniprotkb/A0A8V0YIX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGEAAVAFLGTPAPAAMVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMTLTFGDVVAVRHYEKA", "length": 150, "header": "tr|A0A8V0YIX7-1|A0A8V0YIX7_CHICK Isoform 1 of Fatty acid binding protein 7 OS=Gallus gallus OX=9031 GN=FABP7 PE=3 SV=1 CANONICAL=A0A8V0YIX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW3/entry", "sequence": { "sequence": "MRGGEAAVAFLGTPAPAAMVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMVSVTQNINPGEG", "length": 146, "header": "tr|A0A8V0YGW3-1|A0A8V0YIX7_CHICK Computationally mapped isoform of Fatty acid binding protein 7 OS=Gallus gallus OX=9031 GN=FABP7 PE=3 SV=1 CANONICAL=A0A8V0YIX7-1" }, "locus": { "chromosome": "3", "start_pos": 60867063, "end_pos": 60865368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030627.1", "url": "https://www.ensembl.org/id/ENSGALT00010030627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017762.1", "url": "https://www.ensembl.org/id/ENSGALP00010017762.1" } ] } }, { "isoform_ac": "A0A8V0YIX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7/entry", "sequence": { "sequence": "MRGGEAAVAFLGTPAPAAMVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMTLTFGDVVAVRHYEKA", "length": 150, "header": "tr|A0A8V0YIX7-1|A0A8V0YIX7_CHICK Isoform 1 of Fatty acid binding protein 7 OS=Gallus gallus OX=9031 GN=FABP7 PE=3 SV=1 CANONICAL=A0A8V0YIX7-1" }, "locus": { "chromosome": "3", "start_pos": 60867063, "end_pos": 60863937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030628.1", "url": "https://www.ensembl.org/id/ENSGALT00010030628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017763.1", "url": "https://www.ensembl.org/id/ENSGALP00010017763.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-163560", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" } ], "pmid": "" }, { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX7" }, { "id": "PS00214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytosolic fatty-acid binding proteins", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 42, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YGX9-1", "uniprot_ac": "A0A8V0YGX9", "uniprot_id": "A0A8V0YGX9_CHICK", "mass": { "chemical_mass": 32226.0, "monoisotopic_mass": 32226.0 }, "refseq": { "ac": "XP_004945118", "name": "receptor expression-enhancing protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945118" }, "gene_names": [ { "name": "REEP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9" } ] }, { "name": "REEP2", "type": "synonym", "evidence": [ { "id": "XP_004945118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945118" } ] } ], "protein_names": [ { "name": "Receptor expression-enhancing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YGX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9/entry#names_and_taxonomy" } ] }, { "name": "receptor expression-enhancing protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004945118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945118" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945118", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945118" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REEP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9", "locus": { "chromosome": "13", "start_pos": 17823591, "end_pos": 17813241, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014214", "url": "https://www.ensembl.org/id/ENSGALG00010014214" } ] } } ], "crossref": [ { "id": "A0A8V0YGX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "771891", "url": "https://www.ncbi.nlm.nih.gov/gene/771891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGX4", "url": "https://www.orthodb.org/?gene=A0A8V0YGX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGX9", "url": "https://www.orthodb.org/?gene=A0A8V0YGX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN40", "url": "https://www.orthodb.org/?gene=A0A8V0YN40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945118", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945118", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYEMSEEGEVGGNTAVWKHMEVQGRVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDAVHLQSHESQLRPSGGSLLETIEDSASCYSSGEESSVAQRPNGTPSEIRTDPSDEDAGDKLPKRTQSLKAPKKMTKSELPVKSVKARPKKKAAGSFTSGESS", "length": 288, "header": "tr|A0A8V0YGX9-1|A0A8V0YGX9_CHICK Isoform 1 of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP2 PE=3 SV=1 CANONICAL=A0A8V0YGX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX4/entry", "sequence": { "sequence": "MKFQDVSYDSREDSAILTCCIDYYYSFMLESFLSLYSFCLCCCLPVISICLCDDLDSNLHLSPSFSFSFFPFPLSLRFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDAVHLQSHESQLRPSGGSLLETIEDSASCYSSGEESSVAQRPNGTPSEIRTDPSDEDAGDKLPKRTQSLKAPKKMTKSELPVKSVKARPKKKAAGSFTSGESS", "length": 281, "header": "tr|A0A8V0YGX4-1|A0A8V0YGX9_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP2 PE=3 SV=1 CANONICAL=A0A8V0YGX9-1" }, "locus": { "chromosome": "13", "start_pos": 17821929, "end_pos": 17818880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034245.1", "url": "https://www.ensembl.org/id/ENSGALT00010034245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020120.1", "url": "https://www.ensembl.org/id/ENSGALP00010020120.1" } ] } }, { "isoform_ac": "A0A8V0YGX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX9/entry", "sequence": { "sequence": "MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYEMSEEGEVGGNTAVWKHMEVQGRVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDAVHLQSHESQLRPSGGSLLETIEDSASCYSSGEESSVAQRPNGTPSEIRTDPSDEDAGDKLPKRTQSLKAPKKMTKSELPVKSVKARPKKKAAGSFTSGESS", "length": 288, "header": "tr|A0A8V0YGX9-1|A0A8V0YGX9_CHICK Isoform 1 of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP2 PE=3 SV=1 CANONICAL=A0A8V0YGX9-1" }, "locus": { "chromosome": "13", "start_pos": 17821929, "end_pos": 17813301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034252.1", "url": "https://www.ensembl.org/id/ENSGALT00010034252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020125.1", "url": "https://www.ensembl.org/id/ENSGALP00010020125.1" } ] } }, { "isoform_ac": "A0A8V0YN40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN40/entry", "sequence": { "sequence": "MCWGFFSADIILVCGNDESSLLRGHFAVFLFSDSSDCSFAGEVDDVLDCFCLFHHCRNAHRHCSFLGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDAVHLQSHESQLRPSGGSLLETIEDSASCYSSGEESSVAQRPNGTPSEIRTDPSDEDAGDKLPKRTQSLKAPKKMTKSELPVKSVKARPKKKAAGSFTSGESS", "length": 249, "header": "tr|A0A8V0YN40-1|A0A8V0YGX9_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP2 PE=3 SV=1 CANONICAL=A0A8V0YGX9-1" }, "locus": { "chromosome": "13", "start_pos": 17821929, "end_pos": 17817633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034230.1", "url": "https://www.ensembl.org/id/ENSGALT00010034230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020114.1", "url": "https://www.ensembl.org/id/ENSGALP00010020114.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], 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"", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" }, "gene_names": [ { "name": "TBX22", "type": "recommended", "evidence": [ { "id": "A0A8V0YGY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ] }, { "name": "TBX22", "type": "synonym", "evidence": [ { "id": "NP_989437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" } ] } ], "protein_names": [ { "name": "T-box 22", "type": "synonym", "evidence": [ { "id": "A0A8V0YGY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4/entry#names_and_taxonomy" } ] }, { "name": "T-box transcription factor TBX22", "type": "synonym", "evidence": [ { "id": "NP_989437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF514777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992623, SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_989437.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" } ] }, { "annotation": "Genetic or environmental insults such as those affecting the BMP pathway could lead to a gain-of-function of TBX22 and predispose an individual to cleft lip.", "evidence": [ { "database": "RefSeq", "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" }, { "database": "PubMed", "id": "20033915", "url": "https://glygen.org/publication/PubMed/20033915" } ] }, { "annotation": "Results demonstrate that FGF8 induces Tbx22 in the early face while BMP4 represses and thus restricts its expression. This regulation is conserved between chicken and mouse.", "evidence": [ { "database": "RefSeq", "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" }, { "database": "PubMed", "id": "20845426", "url": "https://glygen.org/publication/PubMed/20845426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBX22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4", "locus": { "chromosome": "4", "start_pos": 1466596, "end_pos": 1461423, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014222", "url": "https://www.ensembl.org/id/ENSGALG00010014222" } ] } } ], "crossref": [ { "id": "A0A8V0YGY4", 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSSRAHAFSVEALVGRSAKRKGPDGRDEESGAGCRQSRRASEPEKRPKAGAESREVGDEVQVELQGSELWKRFHEIGTEMIITKAGRRMFPSVRVKVKGLEPLQQYYIAIDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRLYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVIAQDSRFDLAQIQSLPAEGVRTFSFQETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLEPFPWRPPLALDLKAFGADSQGSSSSSSPVTSSAGTPSPLNPLLSPPCSPPTFHLAVSGVGAPCPESHLPGLGVPLCYRLCPANVLRQQPLILPSHQKPGGPGPPILPHFVVDVPKLSSLGIASLKSAKSEDLSGPCLQVPNSASQMLYGLHASGNIFPSSPIAREALNCSLHPPYGLYGYSFSMPSRLTSAASHFGVSDSLPAAFRDSRCNHPSWHSAINHCL", 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1461600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034261.1", "url": "https://www.ensembl.org/id/ENSGALT00010034261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020130.1", "url": "https://www.ensembl.org/id/ENSGALP00010020130.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The function and regulation of TBX22 in avian frontonasal morphogenesis.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2010-02", "authors": "Higashihori Norihisa, Buchtov\u00e1 Marcela, Richman Joy M", "evidence": [ { "database": "RefSeq", "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" } ], "reference": [ { "type": "PubMed", "id": "20033915", "url": "https://glygen.org/publication/PubMed/20033915" } ] }, { "title": "Regulation of Tbx22 during facial and palatal development.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2010-11", "authors": "Fuchs Alisa, Inthal Andrea, Herrmann David, Cheng Shuofei, Nakatomi Mitsushiro, Peters Heiko, Neub\u00fcser Annette", "evidence": [ { "database": "RefSeq", "id": "NP_989437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989437" } ], "reference": [ { "type": "PubMed", "id": "20845426", "url": "https://glygen.org/publication/PubMed/20845426" } ] } ], "pathway": [ { "id": "gga:373895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373895", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUM5-1", "protein_name": "T-box transcription factor 22", "gene_name": "Tbx22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTKIPPAASSLPGMALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFIEEGEEILSSPSGDSEQPAEKRPKAESSKTVFSCSDNESNSLESLLEESIIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVVEEDSRIDLSLIQSFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWRPSFTMDFKPFVPDTQNGSSGSSPVTSSGGAPSPLNSLLSPSCSPPTVYIPPSSIGMTHPETYLHNVNVPFCYRICPTNYWRPQPFVLPTPERLPSFNSSQSFPPLMMEVPLVSSRGFINSNSGLHEDCNGHCLQASHSTSQMLYGLQNPGNIFHPNPIAQEAICCPFHPPNGCYRYNVSMPPRLENVANHLSENGTNQISFTGGSCDHSHWYPAINHYF", "length": 533 }, "evidence": [ { "id": "A0A8V0YGY4", "url": "https://omabrowser.org/oma/group/A0A8V0YGY4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3N243-1", "protein_name": "T-box transcription factor 22", "gene_name": "TBX22", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALSSRAHAFSVEALVGRPSKRKLQDPREETQPELLEKEGGEEEDRRSSAAAGTKSEPPEKRTKTDPLATTFGFNSFGSLEEKDIIQVELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYYVAIDVVPVDSKRYRYIYHSSQWMIAGNTDHSCITPRVYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVMKQDSRVDMSRIQSLPAEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLETYPWRPSLTLDFKTFSADTQSGSSSSSPVTSSGGAPSPLNSLLSPLCSPPTFHIPTSSLGMPRPEVYLHSINLPLCYKICPNNFWQQQPLVLSALESLASNNSSQSSAPLMMEVPMLSSLGVTNSKNGSSGDLNGQCLQAPKSSNQMYELQALENILSPNPIAQEAIACSFHPSYGFYRYNFSTPPRLVNAANRLKVNDNSQVSFIEGKYNHSHWYPKISHCL", "length": 513 }, "evidence": [ { "id": "A0A8V0YGY4", "url": "https://omabrowser.org/oma/group/A0A8V0YGY4/", "database": "OMA" } ], "glygen_name": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY4" } ], "pmid": "" }, { "name": 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], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-box", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 253, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 301 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 434, "end_pos": 436 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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The reference sequence was derived from JAENSK010000254.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HARS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5", "locus": { "chromosome": "13", "start_pos": 870029, "end_pos": 881458, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012992", "url": "https://www.ensembl.org/id/ENSGALG00010012992" } ] } } ], "crossref": [ { "id": "A0A8V0YJZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00859", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00859", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416132", "url": "https://www.ncbi.nlm.nih.gov/gene/416132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGGGNFK", "url": "https://omabrowser.org/oma/group/CGGGNFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH08", "url": "https://www.orthodb.org/?gene=A0A8V0YH08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YJZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11476:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11476:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00458", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00458", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001383805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17313", "url": "https://www.rhea-db.org/rhea/17313", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEAAVRQQAEVVRRLKQDKAEPDEIAKEVAKLLEMKAHLGGDEGKHKFVLKTPKGTRDYGPKQMAIRERVFSAIIACFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIVQEILSDLQLGDFLIKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKMPWEEVRNEMVGEKGLSPEAADRIGEYVQLHGGMDLIEQLLQDPKLSQNKLAKEGLGDMKLLFEYLTLFGITGKISFDLSLARGLDYYTGVIYEAVLLQQENDHGEESVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGISIGIERIFSILEQRVEASEEKIRTTETQVLVASAQKKLLEERLKLISELWDAGIKAEVLYKKNPKLLNQLQYCEDTGIPLVAIVGEQELKDGVVKLRVVATREEVNIRRESLVEEIRRRTNQL", "length": 501, "header": "tr|A0A8V0YJZ5-1|A0A8V0YJZ5_CHICK Isoform 1 of histidine--tRNA ligase OS=Gallus gallus OX=9031 GN=HARS1 PE=1 SV=1 CANONICAL=A0A8V0YJZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH08/entry", "sequence": { "sequence": "MADEAAVRQQAEVVRRLKQDKAEPDEIAKEVAKLLEMKAHLGGDEGKHKFVLKTPKGTRDYGPKQMAIRERVFSAIIACFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIVQEILSDLQLGDFLIKMPWEEVRNEMVGEKGLSPEAADRIGEYVQLHGGMDLIEQLLQDPKLSQNKLAKEGLGDMKLLFEYLTLFGITGKISFDLSLARGLDYYTGVIYEAVLLQQENDHGEESVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGISIGIERIFSILEQRVEASEEKIRTTETQVLVASAQKKLLEERLKLISELWDAGIKAEVLYKKNPKLLNQLQYCEDTGIPLVAIVGEQELKDGVVKLRVVATREEVNIRRESLVEEIRRRTNQL", "length": 468, "header": "tr|A0A8V0YH08-1|A0A8V0YJZ5_CHICK Computationally mapped isoform of histidine--tRNA ligase OS=Gallus gallus OX=9031 GN=HARS1 PE=1 SV=1 CANONICAL=A0A8V0YJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 881371, "end_pos": 870478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031167.1", "url": "https://www.ensembl.org/id/ENSGALT00010031167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018152.1", "url": "https://www.ensembl.org/id/ENSGALP00010018152.1" } ] } }, { "isoform_ac": "A0A8V0YJZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5/entry", "sequence": { "sequence": "MADEAAVRQQAEVVRRLKQDKAEPDEIAKEVAKLLEMKAHLGGDEGKHKFVLKTPKGTRDYGPKQMAIRERVFSAIIACFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIVQEILSDLQLGDFLIKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKMPWEEVRNEMVGEKGLSPEAADRIGEYVQLHGGMDLIEQLLQDPKLSQNKLAKEGLGDMKLLFEYLTLFGITGKISFDLSLARGLDYYTGVIYEAVLLQQENDHGEESVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGISIGIERIFSILEQRVEASEEKIRTTETQVLVASAQKKLLEERLKLISELWDAGIKAEVLYKKNPKLLNQLQYCEDTGIPLVAIVGEQELKDGVVKLRVVATREEVNIRRESLVEEIRRRTNQL", "length": 501, "header": "tr|A0A8V0YJZ5-1|A0A8V0YJZ5_CHICK Isoform 1 of histidine--tRNA ligase OS=Gallus gallus OX=9031 GN=HARS1 PE=1 SV=1 CANONICAL=A0A8V0YJZ5-1" }, "locus": { "chromosome": "13", "start_pos": 881371, "end_pos": 870478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031171.1", "url": "https://www.ensembl.org/id/ENSGALT00010031171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018156.1", "url": "https://www.ensembl.org/id/ENSGALP00010018156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8D2AAA4-1", "protein_name": "Histidine--tRNA ligase, cytoplasmic", "gene_name": "HARS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRETLEELVRLQGERVRGLKQQKASTEQIEEEVAKLLKLKAQLGPDEGKHKFVLKTPKGTRDYSPRQMAVREKVFDVIIGCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGLFAICGVPDTKFRTICSSVDKLDKMSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGVADKISFDLSLARGLDYYTGVIYEAVLLQPPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKVRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVVKLRSVTSREEVDVRREDLVEEIKRRTSQPSCTC", "length": 509 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8J8YFS5-1", "protein_name": "Histidine--tRNA ligase, cytoplasmic", "gene_name": "Hars1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADRAALEELVRLQGAHVRGLKEQKASAEQIEEEVTKLLKLKAQLGHDEGKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFQVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQAVEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMPTQAGEEPLGVGSIAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQKLEASEEKVRTTETQVLVASAQKKLLEERLKLISELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIRRRTSQPLSM", "length": 508 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QI36-1", "protein_name": "Histidine--tRNA ligase", "gene_name": "hars", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADKAQLQEAIKTQGEVVRKLKSEKASKEQIDEEVARLLQLKAQLGGDEGKHVFVLKTAKGTRDYNPKQMAIREKVFNIIINCFKRHGAETIDSPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQYDAMIPDAECLKLVYEILSELDLGDFRIKVNDRRILDGMFAICGVPDEKFRTICSTVDKLDKLAWEEVKKEMVNEKGLSEEVADRIRDYVSMQGGKDLAERLLQDPKLSQSKQACAGITDMKLLFSYLELFQITDKVVFDLSLARGLDYYTGVIYEAILTQANPAPASTPAEQNGAEDAGVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGVSIGIERVFSIMEQKAELSSEKVRTTETQVLVASAQKNLLEERLKLTAELWNAGIKAEVLYKKNPKLLSQLQHCEDTGIPLVAILGEQELKDGVVKLRNVASREEVDVPRAELVDEVKKRTS", "length": 513 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O82413-1", "protein_name": "Histidine--tRNA ligase, chloroplastic/mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRAIHIVTTRLSSSFRPILLLDLVSSCSPPRQFSIPRRLICAAANGGGRSGSIVAPLVTEEDFHKKIDVNPPKGTRDFPPEDMRLRNWLFNHFKEVSRLYGYEEVDYPVLETEALFIRKAGEEIRDQLYCFEDRGNRRVALRPELTPSLARLVIQKGKSVSLPLKWFAIGQCWRYERMTRGRRREHYQWNMDIIGVPQVTAEAELISSIVTFFKRIGITASDVGFKVSSRKVLQELLKKYGVPEDLFGRVCIIIDKIEKIPIDEIKKELGFTGISEDAIEQLLQVLSVKSLDDLEDIIGGAGEAIADLKQLFSLAEKFGYSEWIQFDASVVRGLAYYTGIVFEGFDRKGKLRAICGGGRYDRLLSTYGGDDFPACGFGFGDAVIVELLKEKDLLPELGQEVENIVCALDKDLQGAAATVATALRDKGQTVDLVLESKPLKWVFKRAARVNARRLVLVGKTEWEDGSVSVKVLSSGEQFQVKLSDLE", "length": 486 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P07263-1", "protein_name": "Histidine--tRNA ligase, mitochondrial", "gene_name": "HTS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSRSLNKVVTSIKSSSIIRMSSATAAATSAPTANAANALKASKAPKKGKLQVSLKTPKGTKDWADSDMVIREAIFSTLSGLFKKHGGVTIDTPVFELREILAGKYGEDSKLIYNLEDQGGELCSLRYDLTVPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVAGTFESMVPDSECLSILVEGLTSLGIKDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAVDKLDKSPWEAVKKEMTEEKGQSEETADKIGEYVKLNGSLKEIHAVLSADANITSNEKAKQGLDDIATLMKYTEAFDIDSFISFDLSLARGLDYYTGLIYEVVTSASAPPENASELKKKAKSAEDASEFVGVGSIAAGGRYDNLVNMFSEASGKKSTQIPCVGISFGVERIFSLIKQRINSSTTIKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGIEAEYVYKAKANPRKQFDAAEKAGCHIAVILGKEEYLEGKLRVKRLGQEFADDDGELVSAADIVPIVQEKLSQIHEDGLNEVTRLIKGL", "length": 546 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P12081-1", "protein_name": "Histidine--tRNA ligase, cytoplasmic", "gene_name": "HARS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC", "length": 509 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KI84-1", "protein_name": "Histidine--tRNA ligase, cytoplasmic", "gene_name": "HARS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADRAALEDLVRVQGERVRGLKQQKASAEQIEEEVAKLLKLKAQLGPDEGKPKFVLKTPKGTRDYSPRQMAVREKVFDVIISCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMLPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQPPARAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKVRTTETQVLVASAQKKLLEERLKLISELWDAGIKAELLYKKNPKLLNQLQYCEETGIPLVAIIGEQELKDGVIKLRSVASREEVDVRREDLVEEIKRRTSQPLCIC", "length": 509 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q61035-1", "protein_name": "Histidine--tRNA ligase, cytoplasmic", "gene_name": "Hars1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADRAALEELVRLQGAHVRGLKEQKASAEQIEEEVTKLLKLKAQLGQDEGKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFLVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQAVEGLGDLKLLFEYLILFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMPTQAGEEPLGVGSIAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEASEEKVRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVASREEVDVRREDLVEEIRRRTNQPLSTC", "length": 509 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IQX8-1", "protein_name": "histidine--tRNA ligase", "gene_name": "HisRS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDTREQILEQIKVQGDLVRQLKAAKESKEKTAPSGGGRVSSSGVPAQRQQQQQPQKQQQAQVQQQQHEQLHQIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGEAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLANEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPAKTSQQNGEQANEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYVASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQGLVKLREVTTREETNVKLEDLAAEIRRRQQASA", "length": 564 }, "evidence": [ { "id": "A0A8V0YJZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YJZ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "histidine-tRNA ligase activity", "id": "GO:0004821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA aminoacylation for protein translation", "id": "GO:0006418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "histidyl-tRNA aminoacylation", "id": "GO:0006427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006427", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17313", "name": "", "equation": "tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJZ5-1", "A0A8V0Y773-1" ], "evidence": [ { "id": "17313", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17313" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y773", "gene_name": "HARS2", "activity": [ { "ec_number": "6.1.1.21", "activity": "tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8V0Y773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y773" } ] }, { "ec_number": "6.1.1.21", "activity": "", "evidence": [ { "id": "A0A8V0Y773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y773" } ] } ] }, { "uniprot_ac": "A0A8V0YJZ5", "gene_name": "HARS1", "activity": [ { "ec_number": "6.1.1.21", "activity": "tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8V0YJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ] }, { "ec_number": "6.1.1.21", "activity": "", "evidence": [ { "id": "A0A8V0YJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" }, { "id": "PS50862", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-transfer RNA synthetases class-II family profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 389, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ5" }, { "id": "PS51185", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51185" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WHEP-TRS", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 55, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.21", "ec_name": "tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+).", "evidence": [ { "id": "6.1.1.21", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.21" }, { "id": "6.1.1.21", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.21" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJ40-1", "uniprot_ac": "A0A8V0YJ40", "uniprot_id": "A0A8V0YJ40_CHICK", "mass": { "chemical_mass": 42573.0, "monoisotopic_mass": 42573.0 }, "refseq": {}, "gene_names": [ { "name": "HIBCH", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ] } ], "protein_names": [ { "name": "3-hydroxyisobutyryl-CoA hydrolase", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry#names_and_taxonomy" } ] }, { "name": "3-hydroxyisobutyryl-coenzyme A hydrolase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry#names_and_taxonomy" } ] }, { "name": "HIB-CoA hydrolase", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry#names_and_taxonomy" } ] }, { "name": "HIBYL-CoA-H", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH36#function" }, { "database": "UniProtKB", "id": "ARBA00024871", "url": "https://www.uniprot.org/uniprotkb/ARBA00024871#function" }, { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HIBCH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40", "locus": { "chromosome": "7", "start_pos": 278051, "end_pos": 240997, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012824", "url": "https://www.ensembl.org/id/ENSGALG00010012824" } ] } } ], "crossref": [ { "id": "A0A8V0YJ40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423979", "url": "https://www.ncbi.nlm.nih.gov/gene/423979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH36", "url": "https://www.orthodb.org/?gene=A0A8V0YH36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ40", "url": "https://www.orthodb.org/?gene=A0A8V0YJ40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43176:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43176:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16113", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16113", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20888", "url": "https://www.rhea-db.org/rhea/20888", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARVLMAPRRLKPFNRLQVILQHLKTCKHTDSAADVLLQKQGGAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRDAGKAGDTMTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEKTVFAMPETAIGLFPDVGGGYFLPRLSGKIGHLLALTGFRLKGRDVLKAGIATHFVESGKLPELEKDLIALKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSANSMEEIVQKLKQDGSPFATKQLEAINKMSPTSLKLTLRQLREGATMSLQDVFTMEYRLSQACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDNCFKPLGNNDLKL", "length": 382, "header": "tr|A0A8V0YJ40-1|A0A8V0YJ40_CHICK Isoform 1 of 3-hydroxyisobutyryl-CoA hydrolase OS=Gallus gallus OX=9031 GN=HIBCH PE=3 SV=1 CANONICAL=A0A8V0YJ40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH36/entry", "sequence": { "sequence": "MTESDGAGCRHGGTRADGAAQKTCKHTDSAADVLLQKQGGAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRAIADAGKAGDTMTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEKTVFAMPETAIGLFPDVGGGYFLPRLSGKIGHLLALTGFRLKGRDVLKAGIATHFVESGKLPELEKDLIALKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSANSMEEIVQKLKQDGSPFATKQLEAINKMSPTSLKLTLRQLREGATMSLQDVFTMEYRLSQACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDNCFKPLGNNDLKL", "length": 381, "header": "tr|A0A8V0YH36-1|A0A8V0YJ40_CHICK Computationally mapped isoform of 3-hydroxyisobutyryl-CoA hydrolase OS=Gallus gallus OX=9031 GN=HIBCH PE=3 SV=1 CANONICAL=A0A8V0YJ40-1" }, "locus": { "chromosome": "7", "start_pos": 276297, "end_pos": 241233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030765.1", "url": "https://www.ensembl.org/id/ENSGALT00010030765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017840.1", "url": "https://www.ensembl.org/id/ENSGALP00010017840.1" } ] } }, { "isoform_ac": "A0A8V0YJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40/entry", "sequence": { "sequence": "MAARVLMAPRRLKPFNRLQVILQHLKTCKHTDSAADVLLQKQGGAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRDAGKAGDTMTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEKTVFAMPETAIGLFPDVGGGYFLPRLSGKIGHLLALTGFRLKGRDVLKAGIATHFVESGKLPELEKDLIALKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSANSMEEIVQKLKQDGSPFATKQLEAINKMSPTSLKLTLRQLREGATMSLQDVFTMEYRLSQACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDNCFKPLGNNDLKL", "length": 382, "header": "tr|A0A8V0YJ40-1|A0A8V0YJ40_CHICK Isoform 1 of 3-hydroxyisobutyryl-CoA hydrolase OS=Gallus gallus OX=9031 GN=HIBCH PE=3 SV=1 CANONICAL=A0A8V0YJ40-1" }, "locus": { "chromosome": "7", "start_pos": 276297, "end_pos": 241264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030760.1", "url": "https://www.ensembl.org/id/ENSGALT00010030760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017836.1", "url": "https://www.ensembl.org/id/ENSGALP00010017836.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "3-hydroxyisobutyryl-CoA hydrolase activity", "id": "GO:0003860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-valine catabolic process", "id": "GO:0006574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006574", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20888", "name": "", "equation": "3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJ60-1", "A0A8V0YJ40-1" ], "evidence": [ { "id": "20888", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20888" } ] }, { "id": "R-GGA-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJ40-1" ], "evidence": [ { "id": "R-GGA-70881", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70881" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJ40", "gene_name": "HIBCH", "activity": [ { "ec_number": "3.1.2.4", "activity": "3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ] }, { "ec_number": "3.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" } ] } ] }, { "uniprot_ac": "Q5ZJ60", "gene_name": "HIBCH", "activity": [ { "ec_number": "3.1.2.4", "activity": "3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+).", "evidence": [ { "id": "Q5ZJ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ60" } ] }, { "ec_number": "3.1.2.4", "activity": "", "evidence": [ { "id": "Q5ZJ60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ60" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ40" }, { "id": "PF16113", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16113" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enoyl-CoA hydratase/isomerase", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 372, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.4", "ec_name": "3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+).", "evidence": [ { "id": "3.1.2.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.4" }, { "id": "3.1.2.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_040560934" }, "gene_names": [ { "name": "METTL18", "type": "recommended", "evidence": [ { "id": "A0A8V0YH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ] }, { "name": "METTL18", "type": "synonym", "evidence": [ { "id": "XP_040560934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560934" } ] } ], "protein_names": [ { "name": "protein-histidine N-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.85", "type": "synonym", "evidence": [ { "id": "A0A8V0YH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60/entry#names_and_taxonomy" } ] }, { "name": "histidine protein methyltransferase 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_040560934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560934" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60", "locus": { "chromosome": "8", "start_pos": 5097686, "end_pos": 5088725, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014298", "url": "https://www.ensembl.org/id/ENSGALG00010014298" } ] } } ], "crossref": [ { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424400", "url": "https://www.ncbi.nlm.nih.gov/gene/424400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LCKCRFF", "url": "https://omabrowser.org/oma/group/LCKCRFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH60", "url": "https://www.orthodb.org/?gene=A0A8V0YH60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040560934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFRFNFFPDEDESKEPSAQRETQPCSPTGEHIEKRLAETKACIKAAKEHHIPADASKVLENKVLETASGLYYVNMSVVELTCQDGTHEEDIVSKSVSSHSDLIPGVYEGGLKIWECTYDLMDFLSEAEIQFANKTVLDLGCGAGLLGIVALRGNAEEVHFQDYNSTVIEEITMPNVVANCINAGNKADSEDDRKNIKPPSKRRKKSECLPDKLTKCRFFSGGWSEVSQLLLSSSKPWSKYDLILTSETIYNPDYYSALHDTLAQLLAKNGRVYLASKVHYFGVGGGTYLFEKFLEERKVFRSSIVKEVEEGLKRFILEIAFKDST", "length": 326, "header": "tr|A0A8V0YH60-1|A0A8V0YH60_CHICK Isoform 1 of protein-histidine N-methyltransferase OS=Gallus gallus OX=9031 GN=METTL18 PE=3 SV=1 CANONICAL=A0A8V0YH60-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60/entry", "sequence": { "sequence": "MDFRFNFFPDEDESKEPSAQRETQPCSPTGEHIEKRLAETKACIKAAKEHHIPADASKVLENKVLETASGLYYVNMSVVELTCQDGTHEEDIVSKSVSSHSDLIPGVYEGGLKIWECTYDLMDFLSEAEIQFANKTVLDLGCGAGLLGIVALRGNAEEVHFQDYNSTVIEEITMPNVVANCINAGNKADSEDDRKNIKPPSKRRKKSECLPDKLTKCRFFSGGWSEVSQLLLSSSKPWSKYDLILTSETIYNPDYYSALHDTLAQLLAKNGRVYLASKVHYFGVGGGTYLFEKFLEERKVFRSSIVKEVEEGLKRFILEIAFKDST", "length": 326, "header": "tr|A0A8V0YH60-1|A0A8V0YH60_CHICK Isoform 1 of protein-histidine N-methyltransferase OS=Gallus gallus OX=9031 GN=METTL18 PE=3 SV=1 CANONICAL=A0A8V0YH60-1" }, "locus": { "chromosome": "8", "start_pos": 5091247, "end_pos": 5090270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034408.1", "url": "https://www.ensembl.org/id/ENSGALT00010034408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020203.1", "url": "https://www.ensembl.org/id/ENSGALP00010020203.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RSC8-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "METTL18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MTFQFNFTIEDHLENELTPIRDGALTLDSSKELSVSESQKGEERDRKCSAEQFDLPQDHLWEHKSMENAAPSQDTDSPLSAASSSRNLEPHGKQPSLRAAKEHAMPKDLKKMLENKVIETLPGFQHVKLSVVKTILLKENFPGENIVSKSFSSHSDLITGVYEGGLKIWECTFDLLAYFTKAKVKFAGKKVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVIDEVTLPNVVANSTLEDEENDVNEPDVKRCRKPKVTQLYKCRFFSGEWSEFCKLVLSSEKLFVKYDLILTSETIYNPDYYSNLHQTFLRLLSKNGRVLLASKAHYFGVGGGVHLFQKFVEERDVFKTRILKIIDEGLKRFIIEITFKFPG", "length": 372 }, "evidence": [ { "id": "A0A8V0YH60", "url": "https://omabrowser.org/oma/group/A0A8V0YH60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KIJ2-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "METTL18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTFQFNFTIEDHLEDELTSLGDGALALHSSKESLVSERQKGTHRDKKCSTEQSDLLQDHLWEHKSERNEAPSQDPDSSFGAANSSSNLEPHEEKPCLKVAKEHAVPKDLKKVLENKVTETLPGLQHVNISIMKTTLLKENFPGENIISKSFSSHSDLISGVYEGGLKIWECTFDLLAYLTKAKVKFAGKKVLDLGCGSGLLGIMALKGGAKEIHFQDYNSVVIDEVTLPNVVANSTLEDEENDVNEPDVKRLRRSTVAQELCKCRFFSGEWSEFCKLVLSSEKLFEKYDLILTSETIYNPDYYVPLHQTFLRLLDKNGQVLLASKVHYFGVGGGTHLFQKFVEERNVFETRTLEIIDEGLKRCLIEMTFKYPT", "length": 373 }, "evidence": [ { "id": "A0A8V0YH60", "url": "https://omabrowser.org/oma/group/A0A8V0YH60/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KM84-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "Mettl18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFQFNFSIEEDLENKLTSLDDGTCVLKSQKGKEDKNQSTELPGLPQDRLWKCSSLGSAASSEDTDSPPSTADRSGVPEACEKQPSLKPAKEHVIPKDCDQVLENKVLEMLPGSQHVSTAVVKTISLKEKFPGENIVSQSFSSHSDLIPGVYEGGLKIWECTFDLMTYFTKAKVKFAGQKVLDLGCGSGLLGITASKGGAREVHFQDYNGLVIDEVTLPNVVANVPLQGDSNGINEPAGKRQRKSEVAQETCKCRLFSGEWAEFCKLVLSEKLFVKYDLILTSETIYNPDYYSTLHETLLRLLSRNGRVLLASKAHYFGVGGGVHLFQKFVEEKGVFETRTLEVIDEGLKRFLMEMTFKCPS", "length": 362 }, "evidence": [ { "id": "A0A8V0YH60", "url": "https://omabrowser.org/oma/group/A0A8V0YH60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CZ09-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "Mettl18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFQFNFSIEEDLENKLTSLDDGTCVLESQKGKQDKRQSTERPGLPRDHSWKCSSLGNAASSEDTGSPPPIADRSDDPEACKHQPSWKPAKEHVMPKDVNHVLENTVLEMLPGPQHANTAVVKTVSLKEKFPGENIVSKSFSSHSDLIPGVYEGGLKIWECTFDLLTYFTKAKVKFAGQKVLDLGCGSGLLGITASKGGAREVHFQDYNGLVIDEVTLPNVVANVPLQDDSNGKNEPDGKRQRKSEVGREICKCRLFSGEWAEFCKLVLREKLFVKYDLILTSETIYNPDYYSTLHETFLRLLSRSGRVLLASKAHYFGVGGGVHLFQKFVEEKGVFETRTLEVIDEGLKRFLMEMTFKHPS", "length": 362 }, "evidence": [ { "id": "A0A8V0YH60", "url": "https://omabrowser.org/oma/group/A0A8V0YH60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of rRNA processing", "id": "GO:2000232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "pmid": "" }, { "name": "regulation of translational elongation", "id": "GO:0006448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006448", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "pmid": "" }, { "name": "regulation of ribosome biogenesis", "id": "GO:0090069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13703:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFRSAGSRRTRRNRSARPNALFSSDGSGGAAHPAVERRRRATAERRSSRGCTYAAGGGRGCCPAKLPRGGGRGAAEGELKALTYAVLKRCKERQLEELLRAVESRGAARTPCVLLPARSEARLGAQRDALPTLLCRVFRWPELRHGAPLKRLRDCCQTDDAATTEFVCCNPHHLSRLCELESPPPPYSRYPMDFLKPMAGCPDSVPSSTETGGTNCLAPGGLSDSQVIQEPGDRSHWCVVAYWEEKMRVGRLYSVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGYGIQLTKEVDGVWVYNRSSYPIFIKSATLDNPDSRMLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWAGFTMQISFVKGWGQCYTRQFISSCPCWLEVIFNDQ", "length": 403, "header": "tr|A0A8V0YH96-1|A0A8V0YH96_CHICK Isoform 1 of Mothers against decapentaplegic homolog OS=Gallus gallus OX=9031 GN=SMAD7B PE=3 SV=1 CANONICAL=A0A8V0YH96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96/entry", "sequence": { "sequence": "MLFRSAGSRRTRRNRSARPNALFSSDGSGGAAHPAVERRRRATAERRSSRGCTYAAGGGRGCCPAKLPRGGGRGAAEGELKALTYAVLKRCKERQLEELLRAVESRGAARTPCVLLPARSEARLGAQRDALPTLLCRVFRWPELRHGAPLKRLRDCCQTDDAATTEFVCCNPHHLSRLCELESPPPPYSRYPMDFLKPMAGCPDSVPSSTETGGTNCLAPGGLSDSQVIQEPGDRSHWCVVAYWEEKMRVGRLYSVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGYGIQLTKEVDGVWVYNRSSYPIFIKSATLDNPDSRMLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWAGFTMQISFVKGWGQCYTRQFISSCPCWLEVIFNDQ", "length": 403, "header": "tr|A0A8V0YH96-1|A0A8V0YH96_CHICK Isoform 1 of Mothers against decapentaplegic homolog OS=Gallus gallus OX=9031 GN=SMAD7B PE=3 SV=1 CANONICAL=A0A8V0YH96-1" }, "locus": { "chromosome": "W", "start_pos": 4332872, "end_pos": 4306822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029507.1", "url": "https://www.ensembl.org/id/ENSGALT00010029507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017149.1", "url": "https://www.ensembl.org/id/ENSGALP00010017149.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "heteromeric SMAD protein complex", "id": "GO:0071144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071144", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "SMAD protein signal transduction", "id": "GO:0060395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" }, { "id": "PS51075", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51075" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MH1", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 184, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YH96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH96" }, { "id": "PS51076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MH2", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 403, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHB1-1", "uniprot_ac": "A0A8V0YHB1", "uniprot_id": "A0A8V0YHB1_CHICK", "mass": { "chemical_mass": 68257.0, "monoisotopic_mass": 68257.0 }, "refseq": {}, "gene_names": [ { "name": "LOC422276", "type": "recommended", "evidence": [ { "id": "A0A8V0YHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ] } ], "protein_names": [ { "name": "Sodium/hydrogen exchanger", "type": "recommended", "evidence": [ { "id": "A0A8V0YHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422276", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA0", "url": "https://www.orthodb.org/?gene=A0A8V0YHA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHB1", "url": "https://www.orthodb.org/?gene=A0A8V0YHB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQC9", "url": "https://www.orthodb.org/?gene=A0A8V0YQC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10110:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGIIYGLNDKSPPVMDSDIFFLYLLPPIVLDAGYFMPSRPFFENIGTILLYAVVGTIWNVFGIGFSLYGICQVRAFGLRDVSLLHNLLFGSLIAAVDPVAVLAVFEEIHVNEKLHILVFGESLLNDAVTVVLYKLFRSFCEMPAIKTVDVFAGVGKFFVVGIGGVLVGLTFGMTSAFTTRFTKDIRVIEPLFVFLYSYLSYLTAEMFHLSGIVAIIACAMGMKRYVEANISLKSHTTVKYFMKMWSSVSDTLIFIFLGVSTIGENHEWNWPYIFFTVIFCLIWRALGVLVLTFFVNRFHVNTVTSKDQFIIAYGGLRGAICFSLVFLLPDFRRKKLFIAATTVVILFTVFAQGMTIRPLVDLLHVKRKRESAPTVGEQIHIRFLDHLLAGIEDISGHWGQYYWKDKLEYFNSKYLQKFLLREYDQPKSSIVLLYEKLERKHAIELAEAGQLGHAPSHPSLLNSNRTVITEKKSEDTLCPDGLEDIQEILARNLYRIRRTGPAYSRHTLPGETEPVEQAQEILILQRRSLRVDASGSDRISPRKEKEGSSLARGDSDVQPRLCRSLTVEDAERVRAVKQNRSQSVCVIPARSKQEGAGKEMASDM", "length": 605, "header": "tr|A0A8V0YHB1-1|A0A8V0YHB1_CHICK Isoform 1 of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=LOC422276 PE=3 SV=1 CANONICAL=A0A8V0YHB1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA0/entry", "sequence": { "sequence": "ASFILVARRRWEGAAPPSAARLEYFNSKYLQKFLLREYDQPKSSIVLLYEKLERKHAIELAEAGQLGHAPSHPSLLNSNRTVITEKKSEDTLCPDGLEDIQEILARNLYRIRRTGPAYSRHTLPGETEPVEQAQEILILQRRSLRVDASGSDRISPRKEKEGSSLARGDSDVQPRLCRSLTVEDAERVRAVKQNRSQSVCVIPARSKQEGAGKEMASDM", "length": 219, "header": "tr|A0A8V0YHA0-1|A0A8V0YHB1_CHICK Computationally mapped isoform of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=LOC422276 PE=3 SV=1 CANONICAL=A0A8V0YHB1-1" }, "locus": { "chromosome": "4", "start_pos": 9270771, "end_pos": 9260636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034458.1", "url": "https://www.ensembl.org/id/ENSGALT00010034458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020240.1", "url": "https://www.ensembl.org/id/ENSGALP00010020240.1" } ] } }, { "isoform_ac": "A0A8V0YHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1/entry", "sequence": { "sequence": "MGGIIYGLNDKSPPVMDSDIFFLYLLPPIVLDAGYFMPSRPFFENIGTILLYAVVGTIWNVFGIGFSLYGICQVRAFGLRDVSLLHNLLFGSLIAAVDPVAVLAVFEEIHVNEKLHILVFGESLLNDAVTVVLYKLFRSFCEMPAIKTVDVFAGVGKFFVVGIGGVLVGLTFGMTSAFTTRFTKDIRVIEPLFVFLYSYLSYLTAEMFHLSGIVAIIACAMGMKRYVEANISLKSHTTVKYFMKMWSSVSDTLIFIFLGVSTIGENHEWNWPYIFFTVIFCLIWRALGVLVLTFFVNRFHVNTVTSKDQFIIAYGGLRGAICFSLVFLLPDFRRKKLFIAATTVVILFTVFAQGMTIRPLVDLLHVKRKRESAPTVGEQIHIRFLDHLLAGIEDISGHWGQYYWKDKLEYFNSKYLQKFLLREYDQPKSSIVLLYEKLERKHAIELAEAGQLGHAPSHPSLLNSNRTVITEKKSEDTLCPDGLEDIQEILARNLYRIRRTGPAYSRHTLPGETEPVEQAQEILILQRRSLRVDASGSDRISPRKEKEGSSLARGDSDVQPRLCRSLTVEDAERVRAVKQNRSQSVCVIPARSKQEGAGKEMASDM", "length": 605, "header": "tr|A0A8V0YHB1-1|A0A8V0YHB1_CHICK Isoform 1 of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=LOC422276 PE=3 SV=1 CANONICAL=A0A8V0YHB1-1" }, "locus": { "chromosome": "4", "start_pos": 9284592, "end_pos": 9260636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034469.1", "url": "https://www.ensembl.org/id/ENSGALT00010034469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020250.1", "url": "https://www.ensembl.org/id/ENSGALP00010020250.1" } ] } }, { "isoform_ac": "A0A8V0YNJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ2/entry", "sequence": { "sequence": "MERQRAGSKGTATVLAVLLSSFLRATGVGALHGSPVAENGSWAAEEAQDNASTEHTFFSLDYQHVQIPFEITLWIMLASLAKIAFHLYNKLPSVVPESCLLIFVGLIMGGIIYGLNDKSPPVMDSDIFFLYLLPPIVLDAGYFMPSRPFFENIGTILLYAVVGTIWNVFGIGFSLYGICQVRAFGLRDVSLLHNLLFGSLIAAVDPVAVLAVFEEIHVNEKLHILVFGESLLNDAVTVVLYKLFRSFCEMPAIKTVDVFAGVGKFFVVGIGGVLVGLTFGMTSAFTTRFTKDIRVIEPLFVFLYSYLSYLTAEMFHLSGIVA", "length": 322, "header": "tr|A0A8V0YNJ2-1|A0A8V0YNJ2_CHICK Computationally mapped isoform of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=LOC422276 PE=3 SV=1 CANONICAL=A0A8V0YHB1-1" }, "locus": { "chromosome": "4", "start_pos": 9285979, "end_pos": 9283844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034448.1", "url": "https://www.ensembl.org/id/ENSGALT00010034448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020234.1", "url": "https://www.ensembl.org/id/ENSGALP00010020234.1" } ] } }, { "isoform_ac": "A0A8V0YQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC9/entry", "sequence": { "sequence": "MERQRAGSKGTATVLAVLLSSFLRATGVGALHGSPVAENGSWAAEEAQDNASTEHTFFSLDYQHVQIPFEITLWIMLASLAKIAFHLYNKLPSVVPESCLLIFVGLIMGGIIYGLNDKSPPVMDSDIFFLYLLPPIVLDAGYFMPSRPFFENIGTILLYAVVGTIWNVFGIGFSLYGICQVRAFGLRDVSLLHNLLFGSLIAAVDPVAVLAVFEEIHVNEKLHILVFGESLLNDAVTVVLYKLFRSFCEMPAIKTVDVFAGVGKFFVVGIGGVLLPFLPHRRDVSPLWHCGVSVPQHLVSLGRTFGCVC", "length": 309, "header": "tr|A0A8V0YQC9-1|A0A8V0YQC9_CHICK Computationally mapped isoform of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=LOC422276 PE=3 SV=1 CANONICAL=A0A8V0YHB1-1" }, "locus": { "chromosome": "4", "start_pos": 9285979, "end_pos": 9283791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034438.1", "url": "https://www.ensembl.org/id/ENSGALT00010034438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020228.1", "url": "https://www.ensembl.org/id/ENSGALP00010020228.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" }, { "name": "regulation of pH", "id": "GO:0006885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" }, { "id": "PF00999", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation/H+ exchanger transmembrane", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 361, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB1" }, { "id": "PF16644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium/hydrogen exchanger regulatory region", "eco_id": "ECO_0000259", "start_pos": 468, "end_pos": 541, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 580, "end_pos": 582 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHF3-1", "uniprot_ac": "A0A8V0YHF3", "uniprot_id": "A0A8V0YHF3_CHICK", "mass": { "chemical_mass": 70989.0, "monoisotopic_mass": 70989.0 }, "refseq": { "ac": "XP_425551", "name": "chloride intracellular channel protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425551" }, "gene_names": [ { "name": "CLIC6", "type": "recommended", "evidence": [ { "id": "A0A8V0YHF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ] }, { "name": "CLIC6", "type": "synonym", "evidence": [ { "id": "XP_425551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425551" } ] } ], "protein_names": [ { "name": "Chloride intracellular channel protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3/entry#names_and_taxonomy" } ] }, { "name": "chloride intracellular channel protein 6", "type": "synonym", "evidence": [ { "id": "XP_425551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425551" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425551.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425551" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLIC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3", "locus": { "chromosome": "1", "start_pos": 106085634, "end_pos": 106056093, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012894", "url": "https://www.ensembl.org/id/ENSGALG00010012894" } ] } } ], "crossref": [ { "id": "A0A8V0YHF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427981", "url": "https://www.ncbi.nlm.nih.gov/gene/427981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427981", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427981", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEWESAA", "url": "https://omabrowser.org/oma/group/CEWESAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHF3", "url": "https://www.orthodb.org/?gene=A0A8V0YHF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPA4", "url": "https://www.orthodb.org/?gene=A0A8V0YPA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425551", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESPGQPVGSDEPRGAGEEEGAEAVGKPQTALCPNGAAEPTDESSDGGGGAGGQEAAAVASEVPSEGGSGEPGGATESPGTGQQEEGELPAPDRDGAALQGGEPAAAAGVDSAPAEVEPEQAAGKVVPVGTEPEEAAVAPAVAGPEEVTVTAPSGSDPEDVVQEVNAVGAEPEEAVRNEGPSGTVPEEAVREEGPLRSSPEEVVRDETASETDPEEAMREAAPSGPEPEEAMREEAPLGTEPEEAVREEAPSGLRPEEGVREDSPSGMEPEEEMREEARVGTDPEDAVQEEASSAPSPEDEGVTEEAPSGAELEKEEEEAPVGDEEAPQRPGVAEDALPAEGETDGGRRSPAGPEGEDGAEVLPGAERGAGTGEAAGTGEESAASGGGGAAAAGRPGGWPDPEGSEWESAGLSLNGVRGRAEDEEDETGSPTALKDEEEKQEYDISLFVKAGSDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLAPKHPESNSAGNDVFAKFSAFIKNPRKDANENLEKSLLKALRKLDNYLNSPLPDEIDAYSTEEITVSCRKFLDGDELTLADCNLLPKLHIIKVVAKKYRNFDFPPEMTGISRYLNNAYARDEFTNTCPADQEIEYAYLDVAKRMK", "length": 679, "header": "tr|A0A8V0YHF3-1|A0A8V0YHF3_CHICK Isoform 1 of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC6 PE=1 SV=1 CANONICAL=A0A8V0YHF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3/entry", "sequence": { "sequence": "MAESPGQPVGSDEPRGAGEEEGAEAVGKPQTALCPNGAAEPTDESSDGGGGAGGQEAAAVASEVPSEGGSGEPGGATESPGTGQQEEGELPAPDRDGAALQGGEPAAAAGVDSAPAEVEPEQAAGKVVPVGTEPEEAAVAPAVAGPEEVTVTAPSGSDPEDVVQEVNAVGAEPEEAVRNEGPSGTVPEEAVREEGPLRSSPEEVVRDETASETDPEEAMREAAPSGPEPEEAMREEAPLGTEPEEAVREEAPSGLRPEEGVREDSPSGMEPEEEMREEARVGTDPEDAVQEEASSAPSPEDEGVTEEAPSGAELEKEEEEAPVGDEEAPQRPGVAEDALPAEGETDGGRRSPAGPEGEDGAEVLPGAERGAGTGEAAGTGEESAASGGGGAAAAGRPGGWPDPEGSEWESAGLSLNGVRGRAEDEEDETGSPTALKDEEEKQEYDISLFVKAGSDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLAPKHPESNSAGNDVFAKFSAFIKNPRKDANENLEKSLLKALRKLDNYLNSPLPDEIDAYSTEEITVSCRKFLDGDELTLADCNLLPKLHIIKVVAKKYRNFDFPPEMTGISRYLNNAYARDEFTNTCPADQEIEYAYLDVAKRMK", "length": 679, "header": "tr|A0A8V0YHF3-1|A0A8V0YHF3_CHICK Isoform 1 of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC6 PE=1 SV=1 CANONICAL=A0A8V0YHF3-1" }, "locus": { "chromosome": "1", "start_pos": 106083842, "end_pos": 106056292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030933.1", "url": "https://www.ensembl.org/id/ENSGALT00010030933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017968.1", "url": "https://www.ensembl.org/id/ENSGALP00010017968.1" } ] } }, { "isoform_ac": "A0A8V0YPA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA4/entry", "sequence": { "sequence": "MAESPGQPVGSDEPRGAGEEEGAEAVGKPQTALCPNGAAEPTDESSDGGGGAGGQEAAAVASEVPSEGGSGEPGGATESPGTGQQEEGELPAPDRDGAALQGGEPAAAAGVDSAPAEVEPEQAAGKVVPVGTEPEEAAVAPAVAGPEEVTVTAPSGSDPEDVVQEVNAVGAEPEEAVRNEGPSGTVPEEAVREEGPLRSSPEEVVRDETASETDPEEAMREEAPLGTEPEEAVREEAPSGLRPEEGVREDSPSGMEPEEEMREEARVGTDPEDAVQEEASSAPSPEDEGVTEEAPSGAELEKEEEEAPVGDEEAPQRPGVAEDALPAEGETDGGRRSPAGPEGEDGAEVLPGAERGAGTGEAAGTGEESAASGGGGAAAAGRPGGWPDPEGSEWESAGLSLNGVRGRAEDEEDETGSPTALKDEEEKQEYDISLFVKAGSDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLAPKHPESNSAGNDVFAKFSAFIKNPRKDANENLEKSLLKALRKLDNYLNSPLPDEIDAYSTEEITVSCRKFLDGDELTLADCNLLPKLHIIKVVAKKYRNFDFPPEMTGISRYLNNAYARDEFTNTCPADQEIEYAYLDVAKRMK", "length": 665, "header": "tr|A0A8V0YPA4-1|A0A8V0YPA4_CHICK Computationally mapped isoform of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC6 PE=1 SV=1 CANONICAL=A0A8V0YHF3-1" }, "locus": { "chromosome": "1", "start_pos": 106083842, "end_pos": 106056292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030945.1", "url": "https://www.ensembl.org/id/ENSGALT00010030945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017977.1", "url": "https://www.ensembl.org/id/ENSGALP00010017977.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427981", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427981", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "D4 dopamine receptor binding", "id": "GO:0031751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031751", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "D2 dopamine receptor binding", "id": "GO:0031749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031749", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "D3 dopamine receptor binding", "id": "GO:0031750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ 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C-terminal", "eco_id": "ECO_0000259", "start_pos": 508, "end_pos": 679, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHG8-1", "uniprot_ac": "A0A8V0YHG8", "uniprot_id": "A0A8V0YHG8_CHICK", "mass": { "chemical_mass": 89540.0, "monoisotopic_mass": 89540.0 }, "refseq": { "ac": "XP_015133812", "name": "oligophrenin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133812" }, "gene_names": [ { "name": "OPHN1", "type": "recommended", "evidence": [ { "id": 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:: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015133812.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133812" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OPHN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8", "locus": { "chromosome": "4", "start_pos": 455832, "end_pos": 502180, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014367", "url": "https://www.ensembl.org/id/ENSGALG00010014367" } ] } } ], "crossref": [ { "id": "A0A8V0YHG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01249", "url": 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"url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015133812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIAAIRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLQEVELERSMMVQNASDLLIKPLENFRKEQIGFTKERKKKFEKDGEKFYSMLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLEYVYQIQEVQESKKFSIVEPVLAFLHSLFTYNNLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREELEDLKKRMKEAPLTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKEAKTLRMTPMDQKPGAKQGTLDLTLKSCVRRKTDSIDKRFCFDIETNERSGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINAVETKGISTEGVYRTVGSNIQVQKLLNAFFDPKCPGDVDLQSSEWDIKTITSSLKFYLRNLSEPVMTYKLHKELVLAAKSENLDYRLGAIHALVYKLPDKNREMLELLIRHLVNVCEHSRENLMSPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYSGPPEDSAAPPVPPPRVAARRHKPITISKRPLRERPVFFGASVEESGADQLSQTPNGSIVTEAPRPLLRSRLPAPRPGGEEPGRPSAELEVGKLVPRLQDGGVKLSSKAANGVVSSPALRTSTLHARRPAPRPGGCGRDGEYDGVPRPRPHGDKPVIMRPPVRPPDPPCRAPIPQKLEQRPDLIAGTAEEVPSSVVASRTKFFETASRRTSSSSSPQGRIPGDES", "length": 789, "header": "tr|A0A8V0YHG8-1|A0A8V0YHG8_CHICK Isoform 1 of Oligophrenin-1 OS=Gallus gallus OX=9031 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A8V0YHG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8/entry", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIAAIRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLQEVELERSMMVQNASDLLIKPLENFRKEQIGFTKERKKKFEKDGEKFYSMLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLEYVYQIQEVQESKKFSIVEPVLAFLHSLFTYNNLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREELEDLKKRMKEAPLTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKEAKTLRMTPMDQKPGAKQGTLDLTLKSCVRRKTDSIDKRFCFDIETNERSGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINAVETKGISTEGVYRTVGSNIQVQKLLNAFFDPKCPGDVDLQSSEWDIKTITSSLKFYLRNLSEPVMTYKLHKELVLAAKSENLDYRLGAIHALVYKLPDKNREMLELLIRHLVNVCEHSRENLMSPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYSGPPEDSAAPPVPPPRVAARRHKPITISKRPLRERPVFFGASVEESGADQLSQTPNGSIVTEAPRPLLRSRLPAPRPGGEEPGRPSAELEVGKLVPRLQDGGVKLSSKAANGVVSSPALRTSTLHARRPAPRPGGCGRDGEYDGVPRPRPHGDKPVIMRPPVRPPDPPCRAPIPQKLEQRPDLIAGTAEEVPSSVVASRTKFFETASRRTSSSSSPQGRIPGDES", "length": 789, "header": "tr|A0A8V0YHG8-1|A0A8V0YHG8_CHICK Isoform 1 of Oligophrenin-1 OS=Gallus gallus OX=9031 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A8V0YHG8-1" }, "locus": { "chromosome": "4", "start_pos": 502095, "end_pos": 458261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034590.1", "url": "https://www.ensembl.org/id/ENSGALT00010034590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020305.1", "url": "https://www.ensembl.org/id/ENSGALP00010020305.1" } ] } }, { "isoform_ac": "A0A8V0YQK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK6/entry", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIAAIRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLQEVELERSMMVQNASDLLIKPLENFRKEQIGFTKERKKKFEKDGEKFYSMLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLEYVYQIQEVQESKKFSIVEPTRNHFSSTREELEDLKKRMKEAPLTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKEAKTLRMTPMDQKPGAKQGTLDLTLKSCVRRKTDSIDKRFCFDIETNERSGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINAVETKGISTEGVYRTVGSNIQVQKLLNAFFDPKCPGDVDLQSSEWDIKTITSSLKFYLRNLSEPVMTYKLHKELVLAAKSENLDYRLGAIHALVYKLPDKNREMLELLIRHLVNVCEHSRENLMSPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYSGPPEDSAAPPVPPPRVAARRHKPITISKRPLRERPVFFGASVEESGADQLSQTPNGSIVTEAPRPLLRSRLPAPRPGGEEPGRPSAELEVGKLVPRLQDGGVKLSSKAANGVVSSPALRTSTLHARRPAPRPGGCGRDGEYDGVPRPRPHGDKPVIMRPPVRPPDPPCRAPIPQKLEQRPDLIAGTAEEVPSSVVASRTKFFETASRRTSSSSSPQGRIPGDES", "length": 754, "header": "tr|A0A8V0YQK6-1|A0A8V0YHG8_CHICK Computationally mapped isoform of Oligophrenin-1 OS=Gallus gallus OX=9031 GN=OPHN1 PE=4 SV=1 CANONICAL=A0A8V0YHG8-1" }, "locus": { "chromosome": "4", "start_pos": 502095, "end_pos": 458261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034583.1", "url": "https://www.ensembl.org/id/ENSGALT00010034583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020303.1", "url": "https://www.ensembl.org/id/ENSGALP00010020303.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422162", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N6J8-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTFTMTPMDQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDIDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTISSSIEPPKPPQYPKMPMQKSVEADPGRKSPSRLVSDVKLETCLEVDVGKLVSRLQDGGTKAIPKASNGPVPGPGTTKAPSFHIKRSAPRPLAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRATTTQKPEPKPDVMAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 803 }, "evidence": [ { "id": "A0A8V0YHG8", "url": "https://omabrowser.org/oma/group/A0A8V0YHG8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A5G2R782-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALIGAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMMPMEQKPGAKQQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINVIESKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFNNSDWDIKTVTSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLEILIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFVKIYSGPPEESTAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHRTPNGTIISSIELPKPLQYPKIPMQRSGEADSGRKSPSRPVSEGKLESCLEVDVGKLVSRLQDGGTKALPKATNGPVPGTGPTKAPSFHIKRPAPRAMAHHKEGDSDSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEIPSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 803 }, "evidence": [ { "id": "A0A8V0YHG8", "url": "https://omabrowser.org/oma/group/A0A8V0YHG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60890-1", "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMTPMEQKPGAKQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEESAAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGTITSSIEPPKPPQHPKLPIQRSGETDPGRKSPSRPILDGKLEPCPEVDVGKLVSRLQDGGTKITPKATNGPMPGSGPTKTPSFHIKRPAPRPLAHHKEGDADSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEITSSVVASRTRFFETASRKTGSSQGRLPGDES", "length": 802 }, "evidence": [ { "id": "A0A8V0YHG8", "url": "https://omabrowser.org/oma/group/A0A8V0YHG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CAX5-1", "protein_name": "Oligophrenin-1", "gene_name": "Ophn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGSALISAMRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCRYEKETRTLTMTPTEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIEANERTGTITLQAPSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFYNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKAVFYTPSLDDVEDEIHHPTPNGTIASNLDPPKQLQHLKLPMQKSGEMDPGRKSPSRPVSDCQTEPCLEADMGKLVYRLQDGGTKAIPKASNGPVPGSGHTKTSSFHIKRPAPRPIVHHKEGDTDCFSKVRPPGEKQTIIRPPVRPPDPPCRSSTSQKPESKPETVSSNAEEIPSSVVASRTRFFETASRKTGSSQGKLPGDES", "length": 802 }, "evidence": [ { "id": "A0A8V0YHG8", "url": "https://omabrowser.org/oma/group/A0A8V0YHG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99J31-1", "protein_name": "Oligophrenin-1", "gene_name": "Ophn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWAKYYCRYEKETRMLTMIPMEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQAPSEANRRLWMEAMDGKEPIYHTPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLYAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKTVFYTSSLDENKDESHHQTPNGTITSNLDPPKLLQHLKPPMQKSGETDPGRKSPSRPVSDCQSEPCLETDVGRLLFRLQDGGTKATPKASNGPVPGSGHTKTSSFHIRRPAPRPMAHHKEGDTDGFSKVRPPGEKQTIIRPPVRPPDPPCRSITPQKPEPKPETGSGNADEIPSSVVASRTRFFETASRKTGSSQGKLPGDES", "length": 802 }, "evidence": [ { "id": "A0A8V0YHG8", "url": "https://omabrowser.org/oma/group/A0A8V0YHG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "cell junction assembly", "id": "GO:0034329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034329", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "establishment of epithelial cell apical/basal polarity", "id": "GO:0045198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG8" } ], "pmid": "" }, { "name": "regulation of Rho protein 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gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"protein_name": "RNA polymerase III subunit G", "gene_name": "POLR3G", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYKPVPLKTGEGEDYVLALKQELRETMKRMPYFVETPEEKQDIERYSKRYMKVDKEEWIPAGPKSKKTKDPGKGTSLTNTADVLKKIEELEKRGDGEKSDEENEEKEGSKEKSKEGDDDDDDDAAEEEEYDEEEQEEENDYINSYFEDGDDFGADSDDNMDEATY", "length": 206 }, "evidence": [ { "id": "A0A8V0YIF2", "url": "https://omabrowser.org/oma/group/A0A8V0YIF2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A1K1-1", "protein_name": "RNA polymerase III subunit G", "gene_name": "Polr3g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYKPVPLKTGEDEDYMLALKQELRETVKRLPYFIETPEEKQDDIERYSKRYMKVYKEEWEPDWRRLPREMMPRKKCKKADPKSKAAKATSKGTTLMNSTDVLKKIEELERRGEGERSDEENDEKEGSKEKEKDEEEDGEEDAEQEEYDEEEQEEENDYINSYFDNGDDFVVDSDDNMDEATY", "length": 223 }, "evidence": [ { "id": "A0A8V0YIF2", "url": "https://omabrowser.org/oma/group/A0A8V0YIF2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15318-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC7", "gene_name": "POLR3G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGNKGRGRAAYTFNIEAVGFSKGEKLPDVVLKPPPLFPDTDYKPVPLKTGEGEEYMLALKQELRETMKRMPYFIETPEERQDIERYSKRYMKVYKEEWIPDWRRLPREMMPRNKCKKAGPKPKKAKDAGKGTPLTNTEDVLKKMEELEKRGDGEKSDEENEEKEGSKEKSKEGDDDDDDDAAEQEEYDEEEQEEENDYINSYFEDGDDFGADSDDNMDEATY", "length": 223 }, "evidence": [ { "id": "A0A8V0YIF2", "url": "https://omabrowser.org/oma/group/A0A8V0YIF2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXY9-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC7", "gene_name": "Polr3g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYKPVPLKTGEDEDYMLALKQELRETVKRLPYFIEPPEEKQDDIERYSKRYMKVYKEEWVPDWRRLPREMMPRKKCKKGDPKSKPSKAAAKATSLINSADVLKTIEELEKRGEGERSDEENEEKEGSKEKDKDDEEDGEEDAEQEDYDEEEQEEENDYINSYFDNGDDFGVDSDDNMDEATY", "length": 223 }, "evidence": [ { "id": "A0A8V0YIF2", "url": "https://omabrowser.org/oma/group/A0A8V0YIF2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF2" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHH3-1", "uniprot_ac": "A0A8V0YHH3", "uniprot_id": "A0A8V0YHH3_CHICK", "mass": { "chemical_mass": 63850.0, "monoisotopic_mass": 63850.0 }, "refseq": { "ac": "XP_046755379", "name": "probable cysteine--tRNA ligase, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755379" }, "gene_names": [ { "name": "CARS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ] }, { "name": "CARS2", "type": "synonym", "evidence": [ { "id": "XP_046755379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755379" } ] } ], "protein_names": [ { "name": "cysteine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.16", "type": "synonym", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3/entry#names_and_taxonomy" } ] }, { "name": "Cysteinyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3/entry#names_and_taxonomy" } ] }, { "name": "probable cysteine--tRNA ligase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046755379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755379" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755379" } ] }, { "annotation": "In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides. CysSSHs behave as potent antioxidants and cellular protectants.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3#function" }, { "database": "UniProtKB", "id": "ARBA00045476", "url": "https://www.uniprot.org/uniprotkb/ARBA00045476#function" }, { "database": "UniProtKB", "id": "A0A8V0YQL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL1#function" } ] }, { "annotation": "Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3#function" }, { "database": "UniProtKB", "id": "ARBA00043868", "url": "https://www.uniprot.org/uniprotkb/ARBA00043868#function" }, { "database": "UniProtKB", "id": "A0A8V0YQL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CARS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3", "locus": { "chromosome": "1", "start_pos": 139177862, "end_pos": 139211010, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014379", "url": "https://www.ensembl.org/id/ENSGALG00010014379" } ] } } ], "crossref": [ { "id": "A0A8V0YHH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00672", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00672", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418757", "url": "https://www.ncbi.nlm.nih.gov/gene/418757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HAWPASE", "url": "https://omabrowser.org/oma/group/HAWPASE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHH3", "url": "https://www.orthodb.org/?gene=A0A8V0YHH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQL1", "url": "https://www.orthodb.org/?gene=A0A8V0YQL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10890:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10890:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046755379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17773", "url": "https://www.rhea-db.org/rhea/17773", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78543", "url": "https://www.rhea-db.org/rhea/78543", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78627", "url": "https://www.rhea-db.org/rhea/78627", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78647", "url": "https://www.rhea-db.org/rhea/78647", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78651", "url": "https://www.rhea-db.org/rhea/78651", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLGAAVRRGRAGGGAARRWRSGAAPRREWVPPAGRACGVVAYNSRSRSKEPLVLAKDGVATWYSCGPTVYDHAHLGHACSYVRFDIIRRILTRFFETEVIMVMGITDIDDKIIRRANEMNISPVALARIYEEDFKQDMASLKVLPPTVYMRVTENIPQIISFIKTIIANGQAYATSQGNVYFDVNSWGERYGVLTAVSPDTQGEAVDTDKRHGRDFALWKAAKPQELSWSSPWGKGRPGWHIECSTISSAVFGKQLDIHTGGIDLAFPHHENEIAQCEVYHQCEQWGNYFLHSGHLHVKGSQEKMSKSLKNYITIKDFLKKFSSDQFRMFCLRSRYSSAVEFSDETMNDAKNVLQAISSFIRDANAYIKGQLVCDPVREDVLWERLASTKVNVKAAFADDFDTSRAVAAIMDLIHHGNRQLKAVTKDAVSPRSSVVYGSITSYIESFFNALGMSLEERQVAVGGGNTALLSNVMDELVSFRTKVRNYALVLPEATEAVQMEEGAVGAKGPKQEQKEKRRQLMQERKPLLEACDSLRGDLAAFGIHIKDRSTASTWEMAEGGRAEQQAEEKS", "length": 572, "header": "tr|A0A8V0YHH3-1|A0A8V0YHH3_CHICK Isoform 1 of cysteine--tRNA ligase OS=Gallus gallus OX=9031 GN=CARS2 PE=1 SV=1 CANONICAL=A0A8V0YHH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3/entry", "sequence": { "sequence": "MLLGAAVRRGRAGGGAARRWRSGAAPRREWVPPAGRACGVVAYNSRSRSKEPLVLAKDGVATWYSCGPTVYDHAHLGHACSYVRFDIIRRILTRFFETEVIMVMGITDIDDKIIRRANEMNISPVALARIYEEDFKQDMASLKVLPPTVYMRVTENIPQIISFIKTIIANGQAYATSQGNVYFDVNSWGERYGVLTAVSPDTQGEAVDTDKRHGRDFALWKAAKPQELSWSSPWGKGRPGWHIECSTISSAVFGKQLDIHTGGIDLAFPHHENEIAQCEVYHQCEQWGNYFLHSGHLHVKGSQEKMSKSLKNYITIKDFLKKFSSDQFRMFCLRSRYSSAVEFSDETMNDAKNVLQAISSFIRDANAYIKGQLVCDPVREDVLWERLASTKVNVKAAFADDFDTSRAVAAIMDLIHHGNRQLKAVTKDAVSPRSSVVYGSITSYIESFFNALGMSLEERQVAVGGGNTALLSNVMDELVSFRTKVRNYALVLPEATEAVQMEEGAVGAKGPKQEQKEKRRQLMQERKPLLEACDSLRGDLAAFGIHIKDRSTASTWEMAEGGRAEQQAEEKS", "length": 572, "header": "tr|A0A8V0YHH3-1|A0A8V0YHH3_CHICK Isoform 1 of cysteine--tRNA ligase OS=Gallus gallus OX=9031 GN=CARS2 PE=1 SV=1 CANONICAL=A0A8V0YHH3-1" }, "locus": { "chromosome": "1", "start_pos": 139210811, "end_pos": 139177950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034604.1", "url": "https://www.ensembl.org/id/ENSGALT00010034604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020311.1", "url": "https://www.ensembl.org/id/ENSGALP00010020311.1" } ] } }, { "isoform_ac": "A0A8V0YQL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL1/entry", "sequence": { "sequence": "MLLGAAVRRGRAGGGAARRWRSGAAPRREWVPPAGRACGVVAYNSRSRSKEPLVLAKDGVATWYSCGPTVYDHAHLGHACSYVRFDIIRRILTRFFETEVIMVMGITDIDDKIIRRANEMNISPVALARIYEEDFKQDMASLKVLPPTVYMRVTENIPQIISFIKTIIANGQAYATSQGNVYFDVNSWGERYGVLTAVSPDTQGEAVDTDKRHGRDFALWKAAKPQELSWSSPWGKGRPGWHIECSTISSAVFGKQLDIHTGGIDLAFPHHENEIAQCEVYHQCEQWGNYFLHSGHLHVKGSQEKMSKSLKNYITIKDFLKKFSSDQFRMFCLRSRYSSAVEFSDETMNDAKNVLQAISSFIRDANAYIKGQLVCDPVREDVLWERLASTKVNVKAAFADDFDTSRAVAAIMDLIHHGNRQLKAVTKVAVGGGNTALLSNVMDELVSFRTKVRNYALVLPEATEAVQMEEGAVGAKGPKQEQKEKRRQLMQERKPLLEACDSLRGDLAAFGIHIKDRSTASTWEMAEGGRAEQQAEEKS", "length": 539, "header": "tr|A0A8V0YQL1-1|A0A8V0YQL1_CHICK Computationally mapped isoform of cysteine--tRNA ligase OS=Gallus gallus OX=9031 GN=CARS2 PE=1 SV=1 CANONICAL=A0A8V0YHH3-1" }, "locus": { "chromosome": "1", "start_pos": 139210811, "end_pos": 139177950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034598.1", "url": "https://www.ensembl.org/id/ENSGALT00010034598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020309.1", "url": "https://www.ensembl.org/id/ENSGALP00010020309.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2J3-1", "protein_name": "cysteine--tRNA ligase", "gene_name": "CARS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRTRGARLGSQLLPAALGLGPASGRAASGARGQEWLQPAGYDTGVKVYNSLTRRKDPLIVSSADAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILTRVFGCSVVMVMGVTDVDDKIIKRANELNVSPASLANLYEEDFKQDMAALKVLPPTVYMRVTENIPQIVAFIAGIIASGHAYSTARGNVYFDLQSRGAKYGKLVGVVPDPMGEPGDSDKRHAGDFALWKAAKPQEPFWASPWGNGRPGWHIECSTLSSLVFGSRLDIHSGGIDLAFPHHENEIAQCEAFHRCPQWGNYFLHSGHLHVEGGEEKMSKSLRNYVTIKDFLRSASPDVFRLFCLRSSYRSAVDYSDGAILEARRLLHAVAAFVEDARAYMRGQLAGGPVREDVLWDRLGRTKGAVQAALADDFNTPRAVDAVVELIHHGNRELKAAAEEPRGPRSPAVLGALVSFVEQFFETVGISLAERQRAAGAGSPAALHSVVEELVRFRQTVRRFALAAGEAAGEARRRQLQERRALLEACDALRRDLSAHGVRIKDRSDVSTWELLDPRTEDPKAGR", "length": 557 }, "evidence": [ { "id": "A0A8V0YHH3", "url": "https://omabrowser.org/oma/group/A0A8V0YHH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZXZ9-1", "protein_name": "Probable cysteine--tRNA ligase, mitochondrial", "gene_name": "Cars2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLGVRASLPLLRCSLAQKPKHFQIPGNEAASGTGRSPVRHGRGFCSSGGAWPSWAWPGLQDFALRLFAGSVPNMLRALRPGPGAPLLRAALVLGRRGRAWQRPQGQDTGVQVHNSLTGKKEPLIVGRSDAVSWYSCGPTVYDHAHLGHACSYVRFDIIRRILTSVFGCNVVMAMSITDVDDKIIKRANEMNVSPASLASLFEEEFKQDMAALKVLPPTVYLRVTENIPQIISFIQGIIAHGHAYATATGSVYFDLRARGDKYGKLVNTVPSATAEPVDSDKRHSSDFALWKGAKPQEVFWASPWGDGRPGWHIECSAMASEVFGSQLDIHTGGIDLAFPHHENEIAQSEVFHQCQQWGNYFLHSGHLHVKGKEEKMSKSLKNYITIKDFLQTFSPDVFRLFCLRTNYRSAIDYSDSTLEEARHLLLGLASFVEDARAYVKGQLICGPVGEDVLWERLASTKKAVKAALANDFDTPRAVNSILDLVHHANRQLRAVSKEAGGPRSPTVFGAIVAYVEQFFETVGISLAKRQCVSGDSSTVALHCVVDELVRFRLKVRQYALATPGATGEARKQQLQERQPLLEACDALRQDLMTHGINVKVSDTAGTGAANVAGSKGADSGWSSSV", "length": 626 }, "evidence": [ { "id": "A0A8V0YHH3", "url": "https://omabrowser.org/oma/group/A0A8V0YHH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SEB2-1", "protein_name": "cysteine--tRNA ligase", "gene_name": "CARS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWTRRACGGAWLLRAARGPEPGRSASGARGQGWLQPTGYDTGVKVYNSLTRRKDPLIVSRADAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILSRVFGCTVVMVMGITDVDDKIIRRANEIRDLCLVSPRVRCPPWPPWKRSARSRDAGVAVGAMSVSPASLARLYEEDFKQDMAALKVLPPTAYLRVTEHVPQIVAFIERLIANGHAYCTAKGNVYFDLQSRGDRYGKLVGVAPGPVGEPVDSDKRHTSDFALWKAAKPQEPFWGSPWGDGRPGWHIECSTIASLVFGSQLDIHSGGVDLAFPHHENEIAQCEAFHQCPQWGNYFLHSGHLHVKGGGEKMSKSLKNYVTIKDFLRSTSPDVFRLFCLRSSYRSAIDYSEGALLEARSLLRATAAFVEDARAYLRGQLAGGPIQEDVLWERLGRTKAAVQAALADDFDTVRAVDAVMDLVHHGNRQLKAASEEPRGPRSPAVLGAVVASVEHFFETVGVSLAERQCVPGAGSPAALHSLVEELVCFRLKVRQFALASGEAPGEARRQRLLERQPLLEACDALRRDLAVHGISIKDRSGSSTWELLDPRTEDPKPRS", "length": 589 }, "evidence": [ { "id": "A0A8V0YHH3", "url": "https://omabrowser.org/oma/group/A0A8V0YHH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BYM8-1", "protein_name": "Probable cysteine--tRNA ligase, mitochondrial", "gene_name": "Cars2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRARGPGPGALLLRAALGLGRRGRSWQRPQGQDTGVQVHNSLTGRKEPLIVARSDAVSWYSCGPTVYDHAHLGHACSYVRFDIIRRILTRVFGCNVVMAMSITDVDDKIIKRANEMNVTPASLASLFEEEFKQDMAALKVLPPTVYLRVTENIPQIIAFIEGIIAHGHAYSTATGSVYFDLHARGDKYGKLVNTVPSATAEPGDSDKRHSSDFALWKAAKPQEVFWASPWGDGRPGWHIECSTMASEVFGSHLDIHTGGIDLAFPHHENEIAQSEVFHQCQQWGNYFLHSGHLHVKGTEEKMSKSLKNYITIKDFLKTFSPDVFRLFCLRTNYRSAIEYSDSTLVEAKHLLLGLASFVEDARAYVKGQLTCGPVEEDVLWERLTSTKKAVKAALANDFDTPRAVNTILDLVHHANRQLRAVSKEASGPRSPTVFGAIISYVEQFFETVGISLANRQCVSGDSSTVTLRCVVDELVRFRLKVRQYALDTPGAAGEARKRQLQERQPLLEACDTLRQDLVTHGINVKDRGSAASTWELLDPRTRHQKPGDRG", "length": 551 }, "evidence": [ { "id": "A0A8V0YHH3", "url": "https://omabrowser.org/oma/group/A0A8V0YHH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HA77-1", "protein_name": "Probable cysteine--tRNA ligase, mitochondrial", "gene_name": "CARS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTTRGPGLGPPLLQAALGLGRAGWHWPAGRAASGGRGRAWLQPTGRETGVQVYNSLTGRKEPLIVAHAEAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILTKVFGCSIVMVMGITDVDDKIIKRANEMNISPASLASLYEEDFKQDMAALKVLPPTVYLRVTENIPQIISFIEGIIARGNAYSTAKGNVYFDLKSRGDKYGKLVGVVPGPVGEPADSDKRHASDFALWKAAKPQEVFWASPWGPGRPGWHIECSAIASMVFGSQLDIHSGGIDLAFPHHENEIAQCEVFHQCEQWGNYFLHSGHLHAKGKEEKMSKSLKNYITIKDFLKTFSPDVFRFFCLRSSYRSAIDYSDSAMLQAQQLLLGLGSFLEDARAYMKGQLACGSVREAMLWERLSSTKRAVKAALADDFDTPRVVDAILGLAHHGNGQLRASLKEPEGPRSPAVFGAIISYFEQFFETVGISLANQQYVSGDGSEATLHGVVDELVRFRQKVRQFALAMPEATGDARRQQLLERQPLLEACDTLRRGLTAHGINIKDRSSTTSTWELLDQRTKDQKSAG", "length": 564 }, "evidence": [ { "id": "A0A8V0YHH3", "url": "https://omabrowser.org/oma/group/A0A8V0YHH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" }, { "name": "cysteine-tRNA ligase activity", "id": "GO:0004817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cysteinyl-tRNA aminoacylation", "id": "GO:0006423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17773", "name": "", "equation": "tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F408-1", "A0A8V0YHH3-1", "A0A8V0ZQK7-1" ], "evidence": [ { "id": "17773", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17773" } ] }, { "id": "78543", "name": "", "equation": "2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHH3-1" ], "evidence": [ { "id": "78543", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78543" } ] }, { "id": "78627", "name": "", "equation": "S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHH3-1" ], "evidence": [ { "id": "78627", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78627" } ] }, { "id": "78647", "name": "", "equation": "S-sulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHH3-1" ], "evidence": [ { "id": "78647", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78647" } ] }, { "id": "78651", "name": "", "equation": "S-disulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHH3-1" ], "evidence": [ { "id": "78651", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78651" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YHH3", "gene_name": "CARS2", "activity": [ { "ec_number": "6.1.1.16", "activity": "tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ] }, { "ec_number": "6.1.1.16", "activity": "", "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" } ] } ] }, { "uniprot_ac": "A0A8V0ZQK7", "gene_name": "CARS", "activity": [ { "ec_number": "6.1.1.16", "activity": "tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZQK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK7" } ] }, { "ec_number": "6.1.1.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK7" } ] } ] }, { "uniprot_ac": "Q5F408", "gene_name": "CARS1", "activity": [ { "ec_number": "6.1.1.16", "activity": "tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate.", "evidence": [ { "id": "Q5F408", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F408" } ] }, { "ec_number": "6.1.1.16", "activity": "", "evidence": [ { "id": "Q5F408", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F408" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH3" }, { "id": "PF01406", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA synthetases class I catalytic", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 352, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.16", "ec_name": "tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate.", "evidence": [ { "id": "6.1.1.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.16" }, { "id": "6.1.1.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHH9-1", "uniprot_ac": "A0A8V0YHH9", "uniprot_id": "A0A8V0YHH9_CHICK", "mass": { "chemical_mass": 22058.0, "monoisotopic_mass": 22058.0 }, "refseq": { "ac": "XP_040512539", "name": "interferon type A1/A2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512539" }, "gene_names": [ { "name": "LOC121106526", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9" } ] }, { "name": "LOC121106526", "type": "synonym", "evidence": [ { "id": "XP_040512539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512539" } ] } ], "protein_names": [ { "name": "Interferon alpha", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9/entry#names_and_taxonomy" } ] }, { "name": "interferon type A1/A2-like", "type": "synonym", "evidence": [ { "id": "XP_040512539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512539" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512539" } ] }, { "annotation": "Has antiviral activities.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9#function" }, { "database": "UniProtKB", "id": "ARBA00002718", "url": "https://www.uniprot.org/uniprotkb/ARBA00002718#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106526", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9", "locus": {} } ], "crossref": [ { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-909733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912694", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040512539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH9-1", "database": "UniProtKB", "categories": [ 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHI1-1", "uniprot_ac": "A0A8V0YHI1", "uniprot_id": "A0A8V0YHI1_CHICK", "mass": { "chemical_mass": 97095.0, "monoisotopic_mass": 97095.0 }, "refseq": { "ac": "XP_416073", "name": "inner nuclear membrane protein Man1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416073" }, "gene_names": [ { "name": "LEMD3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ] }, { "name": "LEMD3", "type": "synonym", "evidence": [ { "id": "XP_416073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416073" } ] } ], "protein_names": [ { "name": "Inner nuclear membrane protein Man1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1/entry#names_and_taxonomy" } ] }, { "name": "LEM domain-containing protein 3", "type": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416073.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416073" } ] }, { "annotation": "Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1#function" }, { "database": "UniProtKB", "id": "ARBA00057490", "url": "https://www.uniprot.org/uniprotkb/ARBA00057490#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LEMD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1", "locus": { "chromosome": "1", "start_pos": 34112506, "end_pos": 34065019, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012372", "url": "https://www.ensembl.org/id/ENSGALG00010012372" } ] } } ], "crossref": [ { "id": "A0A8V0YHI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12942", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12942", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417832", "url": "https://www.ncbi.nlm.nih.gov/gene/417832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13428:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13428:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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protein Man1 OS=Gallus gallus OX=9031 GN=LEMD3 PE=1 SV=1 CANONICAL=A0A8V0YHI1-1" }, "locus": { "chromosome": "1", "start_pos": 34112050, "end_pos": 34065104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029619.1", "url": "https://www.ensembl.org/id/ENSGALT00010029619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017233.1", "url": "https://www.ensembl.org/id/ENSGALP00010017233.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GK62-1", "protein_name": "Inner nuclear membrane protein Man1", "gene_name": "Lemd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"categories": [ "Protein" ] }, { "id": "A0A8V0YHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELRVGNKYRLGRKIGSGSFGDIYLGANIATGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFVTRNPEDMDRERREHEREERMGQLRGSATRALPPGPPAGATGNRLRNVAEPMASTPTSRIQQSGNTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRISASQTSVPFDHLGK", "length": 415, "header": "tr|A0A8V0YJI7-1|A0A8V0YJI7_CHICK Isoform 1 of non-specific serine/threonine protein 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"start_pos": 50987236, "end_pos": 50971237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030985.1", "url": "https://www.ensembl.org/id/ENSGALT00010030985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018005.1", "url": "https://www.ensembl.org/id/ENSGALP00010018005.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-201688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201688", "resource": "Reactome", "description": "WNT mediated activation of DVL" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "non-canonical Wnt signaling pathway", "id": "GO:0035567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" }, { "name": "positive regulation of non-canonical Wnt signaling pathway", "id": "GO:2000052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-2574840", "name": "AJUBA facilitates AURKA autophosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-GGA-2574841" ], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-2574840", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2574840" } ] }, { "id": "R-GGA-2574845", "name": "AJUBA binds centrosome-associated AURKA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-2574845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2574845" } ] }, { "id": "R-GGA-3000310", "name": "AURKA phosphorylates PLK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-3000310", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000310" } ] }, { "id": "R-GGA-3000319", "name": "BORA binds PLK1 and AURKA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-3000319", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000319" } ] }, { "id": "R-GGA-3772435", "name": "WNT signaling stimulates CSNK1-dependent phosphorylation of DVL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-3772435", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3772435" } ] }, { "id": "R-GGA-380272", "name": "Plk1-mediated phosphorylation of Nlp", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-380272", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380272" } ] }, { "id": "R-GGA-380283", "name": "Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V0XQQ4-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-380283", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380283" } ] }, { "id": "R-GGA-380294", "name": "Loss of C-Nap-1 from centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-380294", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380294" } ] }, { "id": "R-GGA-380311", "name": "Recruitment of Plk1 to centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZD40-1" ], "evidence": [ { "id": "R-GGA-380311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380311" } ] }, { "id": "R-GGA-380455", "name": "Recruitment of CDK11p58 to the centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZD40-1" ], "evidence": [ { "id": "R-GGA-380455", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380455" } ] }, { "id": "R-GGA-380508", "name": "Translocation of NuMA to the centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V0XQQ4-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-380508", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380508" } ] }, { "id": "R-GGA-5617816", "name": "RAB3IP stimulates nucleotide exchange on RAB8A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1ABB1-1", "A0A8V1AFH3-1", "A0A8V0Z564-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5617816", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5617816" } ] }, { "id": "R-GGA-5626220", "name": "C2CD3 binds the mother centriole", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-5626220", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626220" } ] }, { "id": "R-GGA-5626223", "name": "C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-5626223", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626223" } ] }, { "id": "R-GGA-5626227", "name": "CP110 and CEP97 dissociate from the centriole", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626227", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626227" } ] }, { "id": "R-GGA-5626228", "name": "The distal appendage proteins recruit TTBK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626228", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626228" } ] }, { "id": "R-GGA-5626681", "name": "Recruitment of transition zone proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626681", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626681" } ] }, { "id": "R-GGA-5638009", "name": "CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0Z564-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5638009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5638009" } ] }, { "id": "R-GGA-8853405", "name": "TPX2 binds AURKA at centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-8853405", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8853405" } ] }, { "id": "R-GGA-8853419", "name": "TPX2 promotes AURKA autophosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0YCY4-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-8853419", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8853419" } ] }, { "id": "R-GGA-9943736", "name": "Casein kinase I phosphorylates CDC25A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-143488" ], "output_participant_list": [ "R-GGA-9944032" ], "enzyme_list": [ "A0A8V1A896-1", "P67962-1", "A0A8V0YJI7-1" ], "evidence": [ { "id": "R-GGA-9943736", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9943736" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-143488", "participant_name": "phospho-CDC25A [nucleoplasm]", "crossref": [ { "id": "A0A8V1A896", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027269", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010040380", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010066114", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-2574841", "participant_name": "phospho-WTIP [cytosol]", "crossref": [ { "id": "ENSGALG00010009398", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010022437", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0Y3K2", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010012919", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9944032", "participant_name": "phospho-CDC25A [nucleoplasm]", "crossref": [ { "id": "ENSGALG00010027269", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010066114", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A896", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010040380", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YJI7", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] } ] }, { "uniprot_ac": "A0A8V0Z564", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z564" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z564" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1ABB1", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] } ] }, { "uniprot_ac": "A0A8V1AFH3", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 277, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHL1-1", "uniprot_ac": "A0A8V0YHL1", "uniprot_id": "A0A8V0YHL1_CHICK", "mass": { "chemical_mass": 63323.0, "monoisotopic_mass": 63323.0 }, "refseq": {}, "gene_names": [ { "name": "ARSK", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] } ], "protein_names": [ { "name": "Arylsulfatase K", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.18", "type": "synonym", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1/entry#names_and_taxonomy" } ] }, { "name": "Glucuronate-2-sulfatase", "type": "synonym", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate. Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1#function" }, { "database": "UniProtKB", "id": "ARBA00045156", "url": "https://www.uniprot.org/uniprotkb/ARBA00045156#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARSK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1", "locus": { "chromosome": "Z", "start_pos": 58228456, "end_pos": 58240423, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013117", "url": "https://www.ensembl.org/id/ENSGALG00010013117" } ] } } ], "crossref": [ { "id": "A0A8V0YHL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHL1", "url": "https://www.orthodb.org/?gene=A0A8V0YHL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46615:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46615:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17261", "url": "https://www.rhea-db.org/rhea/17261", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAVVLPPSTPRAAVCRTMGSGGPLLLLRGLLLVGAAYCAAPRPPRHSSRPNVLLVACDSFDGRLTFYPGNQTVDLPFINFMKRHGSVFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPDYVTWMDLMQKHGYYTQKYGKLDYTSGHHSVSNRVEAWTRDVEFLLRQEGRPKVNLTGDRRHVRVMKTDWQVTDKAVTWIKKEAVNLTQPFALYLGLNLPHPYPSPYAGENFGSSTFLTSPYWLEKVKYEAIKIPTWTALSEMHPVDYYSSYTKNCTGEFTKQEVRRIRAFYYAMCAETDAMLGEIISALQDTDLLKKTIIMFTSDHGELAMEHRQFYKMSMYEGSSHVPLLVMGPGIRKQQQVSAVVSLVDIYPTMLDLARIPVLQNLSGYSLLPLLLEKAEDEVPRRGPRPSWVLSEFHGCNVNASTYMLRTDQWKYITYSDGVSVPPQLFDLSADPDELTNVAIKFPETVQSLDKILRSIVNYPKVSSTVQNYNKKQFISWKQSLGQNYSNVIANLRWHQDWLKEPKKYEDAIDRWLSQREQRK", "length": 554, "header": "tr|A0A8V0YHL1-1|A0A8V0YHL1_CHICK Isoform 1 of Arylsulfatase K OS=Gallus gallus OX=9031 GN=ARSK PE=3 SV=1 CANONICAL=A0A8V0YHL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1/entry", "sequence": { "sequence": "MLGAVVLPPSTPRAAVCRTMGSGGPLLLLRGLLLVGAAYCAAPRPPRHSSRPNVLLVACDSFDGRLTFYPGNQTVDLPFINFMKRHGSVFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPDYVTWMDLMQKHGYYTQKYGKLDYTSGHHSVSNRVEAWTRDVEFLLRQEGRPKVNLTGDRRHVRVMKTDWQVTDKAVTWIKKEAVNLTQPFALYLGLNLPHPYPSPYAGENFGSSTFLTSPYWLEKVKYEAIKIPTWTALSEMHPVDYYSSYTKNCTGEFTKQEVRRIRAFYYAMCAETDAMLGEIISALQDTDLLKKTIIMFTSDHGELAMEHRQFYKMSMYEGSSHVPLLVMGPGIRKQQQVSAVVSLVDIYPTMLDLARIPVLQNLSGYSLLPLLLEKAEDEVPRRGPRPSWVLSEFHGCNVNASTYMLRTDQWKYITYSDGVSVPPQLFDLSADPDELTNVAIKFPETVQSLDKILRSIVNYPKVSSTVQNYNKKQFISWKQSLGQNYSNVIANLRWHQDWLKEPKKYEDAIDRWLSQREQRK", "length": 554, "header": "tr|A0A8V0YHL1-1|A0A8V0YHL1_CHICK Isoform 1 of Arylsulfatase K OS=Gallus gallus OX=9031 GN=ARSK PE=3 SV=1 CANONICAL=A0A8V0YHL1-1" }, "locus": { "chromosome": "Z", "start_pos": 58240400, "end_pos": 58229936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031442.1", "url": "https://www.ensembl.org/id/ENSGALT00010031442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018356.1", "url": "https://www.ensembl.org/id/ENSGALP00010018356.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "pmid": "" }, { "name": "arylsulfatase activity", "id": "GO:0004065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "pmid": "" }, { "name": "glucuronate-2-sulfatase activity", "id": "GO:0015024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17261", "name": "", "equation": "an aryl sulfate + H2O = a phenol + sulfate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZK90-1", "A0A8V0YHL1-1", "A0A8V1AI26-1" ], "evidence": [ { "id": "17261", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17261" } ] }, { "id": "R-GGA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-194653" ], "output_participant_list": [ "R-ALL-1663154" ], "enzyme_list": [ "A0A8V0XXM5-1", "A0A8V1AI26-1", "A0A8V0YHL1-1" ], "evidence": [ { "id": "R-GGA-1614362", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614362" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1663154", "participant_name": "H2S [endoplasmic reticulum lumen]", "crossref": [ { "id": "29919", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-194653", "participant_name": "NAD+ [endoplasmic reticulum lumen]", "crossref": [ { "id": "57540", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214766", "database": "ZINC", "url": "" }, { "id": "C00003", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YHL1", "gene_name": "ARSK", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] }, { "ec_number": "3.1.6.18", "activity": "Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHM9-1", "uniprot_ac": "A0A8V0YHM9", "uniprot_id": "A0A8V0YHM9_CHICK", "mass": { "chemical_mass": 21937.0, "monoisotopic_mass": 21937.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9/entry#names_and_taxonomy" } ] }, { "name": "Complex I-MWFE", "type": "synonym", "evidence": [ { "id": "A0A8V0YHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase MWFE subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0YHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9", "locus": { "chromosome": "4", "start_pos": 16450074, "end_pos": 16451906, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012934", "url": "https://www.ensembl.org/id/ENSGALG00010012934" } ] } } ], "crossref": [ { "id": "A0A8V0YHM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR017384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHM9", "url": "https://www.orthodb.org/?gene=A0A8V0YHM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17098:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17098:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LRRSSRPSRPPPPSRLPARQGPRAAPWAWRSPCPPSSRAAGQRRAPQRAHWPRASRGCASAGRQPRPRPRPLHPRAAWKATTSGAPRAEWKTTTSGVPLAAGRSAAPGAGRAGSALSRTESGGGGGRGGSTGAMWYEILPGMAIMGVCLSIPGLSTIYMHRWCNGGKEKRIARNPYQWTLMERDRRLSGVNKYYVSKGLENID", "length": 203, "header": "tr|A0A8V0YHM9-1|A0A8V0YHM9_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 OS=Gallus gallus OX=9031 GN=NDUFA1 PE=1 SV=1 CANONICAL=A0A8V0YHM9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9/entry", "sequence": { "sequence": "LRRSSRPSRPPPPSRLPARQGPRAAPWAWRSPCPPSSRAAGQRRAPQRAHWPRASRGCASAGRQPRPRPRPLHPRAAWKATTSGAPRAEWKTTTSGVPLAAGRSAAPGAGRAGSALSRTESGGGGGRGGSTGAMWYEILPGMAIMGVCLSIPGLSTIYMHRWCNGGKEKRIARNPYQWTLMERDRRLSGVNKYYVSKGLENID", "length": 203, "header": "tr|A0A8V0YHM9-1|A0A8V0YHM9_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 OS=Gallus gallus OX=9031 GN=NDUFA1 PE=1 SV=1 CANONICAL=A0A8V0YHM9-1" }, "locus": { "chromosome": "4", "start_pos": 16451146, "end_pos": 16450150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031040.1", "url": "https://www.ensembl.org/id/ENSGALT00010031040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018044.1", "url": "https://www.ensembl.org/id/ENSGALP00010018044.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHQ9-1", "uniprot_ac": "A0A8V0YHQ9", "uniprot_id": "A0A8V0YHQ9_CHICK", "mass": { "chemical_mass": 88037.0, "monoisotopic_mass": 88037.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGVGAARRSWAAAVVVLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVSENSPSGSRFPLEGASDADIGSNAQLSYTLSPSEHFALDVKISDEDRKSLFLVLTHPLDRESLSDHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVTATDPDEGINQEFSYSIVNTVPASQRDSFSIDPRTGEIRLTGPLDFEEVRINELQIEARDKGFPPLSGHCSVELEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPAPKETPQEPSSLLDT", "length": 844, "header": "tr|A0A8V0YHQ9-1|A0A8V0YHQ9_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9/entry", "sequence": { "sequence": "MVGVGAARRSWAAAVVVLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVSENSPSGSRFPLEGASDADIGSNAQLSYTLSPSEHFALDVKISDEDRKSLFLVLTHPLDRESLSDHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVTATDPDEGINQEFSYSIVNTVPASQRDSFSIDPRTGEIRLTGPLDFEEVRINELQIEARDKGFPPLSGHCSVELEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPAPKETPQEPSSLLDT", "length": 844, "header": "tr|A0A8V0YHQ9-1|A0A8V0YHQ9_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHQ9-1" }, "locus": { "chromosome": "13", "start_pos": 942498, "end_pos": 939967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029754.1", "url": "https://www.ensembl.org/id/ENSGALT00010029754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017321.1", "url": "https://www.ensembl.org/id/ENSGALP00010017321.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ9" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 131, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 556, "end_pos": 558 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHT1-1", "uniprot_ac": "A0A8V0YHT1", "uniprot_id": "A0A8V0YHT1_CHICK", "mass": { "chemical_mass": 92965.0, "monoisotopic_mass": 92965.0 }, "refseq": { "ac": "NP_001305331", "name": "complement component C7 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331" }, "gene_names": [ { "name": "C7", "type": "recommended", "evidence": [ { "id": "A0A8V0YHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ] }, { "name": "C7", "type": "synonym", "evidence": [ { "id": "NP_001305331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331" } ] } ], "protein_names": [ { "name": "Complement component C7", "type": "recommended", "evidence": [ { "id": "A0A8V0YHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1/entry#names_and_taxonomy" } ] }, { "name": "complement component 7", "type": "synonym", "evidence": [ { "id": "NP_001305331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331" } ] }, { "name": "complement component C7 precursor", "type": "synonym", "evidence": [ { "id": "NP_001305331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HQ878377.1, SRR12888548.203731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000089.1. On Sep 23, 2021 this sequence version replaced NP_001305331.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001305331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331" } ] }, { "annotation": "Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C7 serves as a membrane anchor. During MAC assembly, associates with C5b and C6 to form the C5b-7 complex, a key lipophilic precursor of the MAC complex, which associates with the outer leaflet and reduces the energy for membrane bending.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS1#function" }, { "database": "UniProtKB", "id": "ARBA00093281", "url": "https://www.uniprot.org/uniprotkb/ARBA00093281#function" }, { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1#function" }, { "database": "UniProtKB", "id": "A0A8V0YMK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1", "locus": { "chromosome": "Z", "start_pos": 13489464, "end_pos": 13469165, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012427", "url": "https://www.ensembl.org/id/ENSGALG00010012427" } ] } } ], "crossref": [ { "id": "A0A8V0YHT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427187", "url": "https://www.ncbi.nlm.nih.gov/gene/427187", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427187", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427187", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQNGGQP", "url": "https://omabrowser.org/oma/group/CQNGGQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHS1", "url": "https://www.orthodb.org/?gene=A0A8V0YHS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHT1", "url": "https://www.orthodb.org/?gene=A0A8V0YHT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMK1", "url": "https://www.orthodb.org/?gene=A0A8V0YMK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45742:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45742:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-166665", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166665", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001305331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMLGIFLLLEVSGFFPIFSSPSRPVNCHWNSFGPWSECDGCTHKQVRRRTVAVYGQYGGNPCSGDAFETRPCTPTRGCPTEDGCGDRFRCSSGQCISRSLVCNGDQDCEEDGTDEDQCEEKLTVCDTDKTPPNSELTGQGFDAVTGETRGRVIHTKNFGGQCRKVFSGDGREYYRLSESVLAYTFQVKIQNDFSYEFFNSSWSYMKHTEKKKKSNSGHSYSEKKNEQQSRKSRHLMVVENTVEVAQFINNNPEFLTLAEPFWKELANLPVFYDYSAYRRFIENFGTHFLHSGSLGGQYKVIFYMDTDKMKAEDMSITDMYQCTTSGWNFFIVKKKKTKCSKLDELLQTSSGSSGSKIRGDPYIEGGSPSAVAGLSYLDLDDPAGNNQRYSTWARSVTDYPRVIKQKLTPLYELVKEVPCSSVKKHYLKQSIEEYMAENDPCKCQPCQNGGEAAVEGTQCTCYCKPYTFGAACELGTLVQDQPGVVDGHWSCWSSWSSCSGERKARSRTCNNPSPSGGGKDCIGEQHESRPCEDEELQHFRFIEPHCFDTSITPTEFCSPPPVLANGFVRNAENSYPVGKTIVYACRHGYALIGNPVAKCGSNLEWQGGDRYCQETSCLLPLLEGGLQGEPWKPSYEIGERITLSCPHGMHLEGADSILCEPSLKWTPDMKTIQCKKAVPSVKPEVTEPKCQPWEKVQQSQCVCKLPYECGPSLDICATDPRTERSVHLTVCKMYALECMGRKYSLTNAANCKARQAAERSCGSCCSWEKCEARSNSCVCDEDAPCEEGGIRVCAAVSDFSAHQTMTECEVGRLQCRGQTVTIVSIRPCDAQTK", "length": 834, "header": "tr|A0A8V0YHT1-1|A0A8V0YHT1_CHICK Isoform 1 of Complement component C7 OS=Gallus gallus OX=9031 GN=C7 PE=1 SV=1 CANONICAL=A0A8V0YHT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS1/entry", "sequence": { "sequence": "MKMLGIFLLLEVSGFFPIFSSPSRPVNCHWNSFGPWSECDGCTHKQVRRRTVAVYGQYGGNPCSGDAFETRPCTPTRGCPTEDGCGDRFRCSSGQCISRSLVCNGDQDCEEDGTDEDQCEEKLTVCDTDKTPPNSELTGQGFDAVTGETRGRVIHTKNFGGQCRKVFSGDGREYYRLSESVLAYTFQVKIQNDFSYEFFNSSWSYMKHTEKKKKSNSGHSYSEKKNEQQSRKSRHLMVVENTVEVAQFINNNPEFLTLAEPFWKELANLPVFYDYSAYRRFIENFGTHFLHSGSLGGQYKVIFYMDTDKMKAEDMSITDMYQCTTSGWNFFIVKKKKTKCSKLDELLQTSSGSSGSKIRGDPYIEGGSPSAVAGLSYLDLDDPAGNNQRYSTWARSVTDYPRVIKQKLTPLYELVKEVPCSSVKKHYLKQSIEEYMAENDPCKCQPCQNGGEAAVEGTQCTCYCKPYTFGAACELGTLVQDQPGVVDGHWSCWSSWSSCSGERKARSRTCNNPSPSGGGKDCIGEQHESRPCEDEELQHFRFIEPHCFDTSITPTEFCSPPPVLANGFVRNAENSYPVGKTIVYACRHGYALIGNPVAKCGSNLEWQGGDRYCQETSCLLPLLEGGLQGEPWKPSYEIGERITLSCPHGMHLEGADSILCEPSLKWTPDMKTIQCKKAVPSVKPEVTEPKCQPWEKVQQSQCVCKLPYECGPSLDICATDPRTERSVHLTVCKMYALECMGRKYSLTNAANCKARQAAERSCGSCCSWEKCEVAVALCWCSTSNLPSSMGHTLLLSGYKPFTQCLVS", "length": 807, "header": "tr|A0A8V0YHS1-1|A0A8V0YHT1_CHICK Computationally mapped isoform of Complement component C7 OS=Gallus gallus OX=9031 GN=C7 PE=1 SV=1 CANONICAL=A0A8V0YHT1-1" }, "locus": { "chromosome": "Z", "start_pos": 13486914, "end_pos": 13469308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029777.1", "url": "https://www.ensembl.org/id/ENSGALT00010029777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017336.1", "url": "https://www.ensembl.org/id/ENSGALP00010017336.1" } ] } }, { "isoform_ac": "A0A8V0YHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1/entry", "sequence": { "sequence": "MKMLGIFLLLEVSGFFPIFSSPSRPVNCHWNSFGPWSECDGCTHKQVRRRTVAVYGQYGGNPCSGDAFETRPCTPTRGCPTEDGCGDRFRCSSGQCISRSLVCNGDQDCEEDGTDEDQCEEKLTVCDTDKTPPNSELTGQGFDAVTGETRGRVIHTKNFGGQCRKVFSGDGREYYRLSESVLAYTFQVKIQNDFSYEFFNSSWSYMKHTEKKKKSNSGHSYSEKKNEQQSRKSRHLMVVENTVEVAQFINNNPEFLTLAEPFWKELANLPVFYDYSAYRRFIENFGTHFLHSGSLGGQYKVIFYMDTDKMKAEDMSITDMYQCTTSGWNFFIVKKKKTKCSKLDELLQTSSGSSGSKIRGDPYIEGGSPSAVAGLSYLDLDDPAGNNQRYSTWARSVTDYPRVIKQKLTPLYELVKEVPCSSVKKHYLKQSIEEYMAENDPCKCQPCQNGGEAAVEGTQCTCYCKPYTFGAACELGTLVQDQPGVVDGHWSCWSSWSSCSGERKARSRTCNNPSPSGGGKDCIGEQHESRPCEDEELQHFRFIEPHCFDTSITPTEFCSPPPVLANGFVRNAENSYPVGKTIVYACRHGYALIGNPVAKCGSNLEWQGGDRYCQETSCLLPLLEGGLQGEPWKPSYEIGERITLSCPHGMHLEGADSILCEPSLKWTPDMKTIQCKKAVPSVKPEVTEPKCQPWEKVQQSQCVCKLPYECGPSLDICATDPRTERSVHLTVCKMYALECMGRKYSLTNAANCKARQAAERSCGSCCSWEKCEARSNSCVCDEDAPCEEGGIRVCAAVSDFSAHQTMTECEVGRLQCRGQTVTIVSIRPCDAQTK", "length": 834, "header": "tr|A0A8V0YHT1-1|A0A8V0YHT1_CHICK Isoform 1 of Complement component C7 OS=Gallus gallus OX=9031 GN=C7 PE=1 SV=1 CANONICAL=A0A8V0YHT1-1" }, "locus": { "chromosome": "Z", "start_pos": 13488365, "end_pos": 13469308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029795.1", "url": "https://www.ensembl.org/id/ENSGALT00010029795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017347.1", "url": "https://www.ensembl.org/id/ENSGALP00010017347.1" } ] } }, { "isoform_ac": "A0A8V0YMK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK1/entry", "sequence": { "sequence": "FQMLGIFLLLEVSGFFPIFSSPSRPVNCHWNSFGPWSECDGCTHKQVRRRTVAVYGQYGGNPCSGDAFETRPCTPTRGCPTEDGCGDRFRCSSGQCISRSLVCNGDQDCEEDGTDEDQCEEKLTVCDTDKTPPNSELTGQGFDAVTGETRGRVIHTKNFGGQCRKVFSGDGREYYRLSESVLAYTFQVKIQNDFSYEFFNSSWSYMKHTEKKKKSNSGHSYSEKKNEQQSRKSRHLMVVENTVEVAQFINNNPEFLTLAEPFWKELANLPVFYDYSAYRRFIENFGTHFLHSGSLGGQYKVIFYMDTDKMKAEDMSITDMYQCTTSGWNFFIVKKKKTKCSKLDELLQTSSGSSGSKIRGDPYIEGGSPSAVAGLSYLDLDDPAGNNQRYSTWARSVTDYPRVIKQKLTPLYELVKEVPCSSVKKHYLKQSIEEYMAENDPCKCQPCQNGGEAAVEGTQCTCYCKPYTFGAACELGTLVQDQPGVVDGHWSCWSSWSSCSGERKARSRTCNNPSPSGGGKDCIGEQHESRPCEDEELQHFRFIEPHCFDTSITPTEFCSPPPVLANGFVRNAENSYPVGKTIVYACRHGYALIGNPVAKCGSNLEWQGGDRYCQETSCLLPLLEGGLQGEPWKPSYEIGERITLSCPHGMHLEGADSILCEPSLKWTPDMKTIQCKKAVPSVKPEVTEPKCQPWEKVQQSQCVCKLPYECGPSLDICATDPRTERSVHLTVCKMYALECMGRKYSLTNAANCKARQAAERSCGSCCSWEKCEARSNSCVCDEDAPCEEGGIRVCAAVSDFSAHQTMTECEVGRLQCRGQTVTIVSIRPCDAQTK", "length": 834, "header": "tr|A0A8V0YMK1-1|A0A8V0YMK1_CHICK Computationally mapped isoform of Complement component C7 OS=Gallus gallus OX=9031 GN=C7 PE=1 SV=1 CANONICAL=A0A8V0YHT1-1" }, "locus": { "chromosome": "Z", "start_pos": 13488365, "end_pos": 13469585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029784.1", "url": "https://www.ensembl.org/id/ENSGALT00010029784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017340.1", "url": "https://www.ensembl.org/id/ENSGALP00010017340.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427187", "resource": "KEGG Pathway" }, { "id": "R-GGA-166665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166665", "resource": "Reactome", "description": "Terminal pathway of complement" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YXF5-1", "protein_name": "Complement component C7", "gene_name": "C7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVTSLLILVCFIAAFQVFSRASSPVNCKWDSYGPWSECNGCTKTQTRRRSVAVYGQYGGYPCEGSAFETQSCKPERGCPTEEGCGDRFRCFSGQCISKSLVCNGDPDCEEDGADEDKCENVANPSCNIDKPPPNIELTGYGYNVVTGQGKKRVINTKSFGGQCRKVFSGDGKDFYRLSGNILSYTFQVKVDNDFNYEFYNSSWSYIKHTSTEQNTFYSWKGLFSHSRNTYGHGSAKEEIDTKMKSYKLLVVQNTVEVAQFTNNNPEFLQVAEPFWKELSHLPTLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSGSAKETGFQSDQDNACSSADFQFLFTSSADQRCMKQLETEKSTSGNKGRLLRGKPLVRGGDSGFVADLSFLDLDNPAGNKQRYSSWAGSVTRLPQVIKEKLAPLYELVKEVPCASVKRLYLKRAIEEYFDEFDPCHCRPCQNGGLAIVVETQCQCLCKPYTFGSACEQGVLVGDQAGGVDGGWNCWSSWSPCVQGKRTRSRECNNPPPRDDGKSCLGETTESKQCEDQDLEKLRLLEPHCFHSSLAPKEFCLSPPALKDGFVQGEGTMVPVGQSVVYACDEGYSLIGDPVARCGEDLQWLVGEMHCQKLACVLPGEMNGMQSHPQKPFYMVGEKVTLSCVGGMSLEGPSTLLCGSSLKWSPELKDAKCVQKATSTPPPAAPACQPWEKLQNSKCICKMPYECGSSLDVCARDESRNKILSLTICKMHVVHCHKRNYTLVGKESCTLPSPAEKVCGACPIWSKCDAQNGKCICREASECQTAGYRICVEVNGKEETMSECEAGILRCRGQSISITAIKPCAEEAAQ", "length": 845 }, "evidence": [ { "id": "A0A8V0YHT1", "url": "https://omabrowser.org/oma/group/A0A8V0YHT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1N045-1", "protein_name": "Complement component C7", "gene_name": "C7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKAITLLFLVGFIGEFQVFSSASSPINCQWGSYAPWSECNGCTKTQTRRRSIAVYGQYGGHSCVGSAFETQPCQPTRGCPTEDGCGERFRCFSGQCISKSLVCNGDSDCEEDGADEDRCEDAESRPACDKDKPPPNIELTGRGYNALTGQFRNQVLNTKSFGGQCRKVYSGDGRDFYRLSGNILSYTFQVKINNDFNNEFYNSTWAYVKETSTEHSSSSKGRFLFFSSSSSSHGYSSNTNILTKKKSYQLLVLQNTVEVAQFINNNPEFLQLAESFWKELSYLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYKVIFHMDSEKVKKFDFHSEDKRKCASSHFQFLFTSSKQKCTTMEEVLKSVSENEGNLLRGVPFVRGGHSGFLAGLSYLDLNNPAGNKRRYSQWAGSVPDLPEVIKQKLTPLYELVKEVPCASVKKLYLKRAIEEYLDEFDPCHCRPCHNGGMATVQGSQCQCYCKPKTSGVACEQGVLLGDQAGGVDGGWNCWSSWGPCVQGKKTRSRQCNNPSPSAGGKSCIGETSETRQCEDGELEHLRLLEPHCFPLSLVPTKFCSSPPALKDGFVQDEGATFPVGKNIMYTCKEGYSLVGDPVARCGEDLQWLVGNMHCQKIACVLPALMDGIQSHPHKPFYTIGEKVTISCSGGRSLEGPSTFLCSSSLKWSPEVKDVQCVQREAPLTPKVPKCQPWEKLQNSRCVCKMPYECGSSLGVCARDERSKRILPLTVCKMHVLQCQGRNYTVAGRESCTLPASAEKACGVCPLWEKCDAEGSECVCRAASECEEAGFSVCVEVNGREQTMTECEAGVLRCRGLSISVTGIRPCAAEAA", "length": 843 }, "evidence": [ { "id": "A0A8V0YHT1", "url": "https://omabrowser.org/oma/group/A0A8V0YHT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10643-1", "protein_name": "Complement component C7", "gene_name": "C7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ", "length": 843 }, "evidence": [ { "id": "A0A8V0YHT1", "url": "https://omabrowser.org/oma/group/A0A8V0YHT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "membrane attack complex", "id": "GO:0005579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "other organism cell membrane", "id": "GO:0044218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "complement activation", "id": "GO:0006956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" }, { "name": "complement activation, GZMK pathway", "id": "GO:0160257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160257", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "wide pore channel activity", "id": "GO:0022829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" }, { "id": "PS51412", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51412" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MACPF", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 443, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT1" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 556, "end_pos": 615, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHV2-1", "uniprot_ac": "A0A8V0YHV2", "uniprot_id": "A0A8V0YHV2_CHICK", "mass": { "chemical_mass": 44332.0, "monoisotopic_mass": 44332.0 }, "refseq": { "ac": "NP_001019754", "name": "somatostatin receptor type 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754" }, "gene_names": [ { "name": "SSTR3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ] }, { "name": "SS3R", "type": "synonym", "evidence": [ { "id": "NP_001019754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754" } ] }, { "name": "SSTR3", "type": "synonym", "evidence": [ { "id": "NP_001019754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754" } ] } ], "protein_names": [ { "name": "Somatostatin receptor 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2/entry#names_and_taxonomy" } ] }, { "name": "somatostatin receptor type 3", "type": "synonym", "evidence": [ { "id": "NP_001019754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01019849.1, DQ003337.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992528 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 7, 2021 this sequence version replaced NP_001019754.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001019754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSTR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2", "locus": { "chromosome": "1", "start_pos": 51473976, "end_pos": 51463017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014599", "url": "https://www.ensembl.org/id/ENSGALG00010014599" } ] } } ], "crossref": [ { "id": "cd15972", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15972", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427907", "url": "https://www.ncbi.nlm.nih.gov/gene/427907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427907", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVPACPP", "url": "https://omabrowser.org/oma/group/EVPACPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHV2", "url": "https://www.orthodb.org/?gene=A0A8V0YHV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001019754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTSAFSLPTPTVSEEGNASGSWAGFTTPNSSTTTTSPGVVVSGILIPMVYLIVCVVGLIGNSLVIYVVLRHSVSESVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSFMCRLVMAVDAINQFTSIFCLTVMSVDRYLAVVHPGKSSKWRTARVAKAVSATVWMLSSIVVLPVVVFSDVPLGMNTCHIQWPEPASVWRAGFIIYTATLGFFGPLLVICLCYLLIVVKVRSSGRRVRALSSKHKLSERRVTRMVVTVVAVFVLCWLPFYVLNIINVVCPLPEEPSLFGVYFLVVVLPYANSCANPIIYGFLSYRFKQGFRRAIFRPSRRVQSQEVPECPPEKSDDGGEEKEISKITQNGNDREERPLSSRAGERNGQKPLPEEPVGCEKSSKLHVSYL", "length": 402, "header": "tr|A0A8V0YHV2-1|A0A8V0YHV2_CHICK Isoform 1 of Somatostatin receptor 3 OS=Gallus gallus OX=9031 GN=SSTR3 PE=3 SV=1 CANONICAL=A0A8V0YHV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2/entry", "sequence": { "sequence": "MDTSAFSLPTPTVSEEGNASGSWAGFTTPNSSTTTTSPGVVVSGILIPMVYLIVCVVGLIGNSLVIYVVLRHSVSESVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSFMCRLVMAVDAINQFTSIFCLTVMSVDRYLAVVHPGKSSKWRTARVAKAVSATVWMLSSIVVLPVVVFSDVPLGMNTCHIQWPEPASVWRAGFIIYTATLGFFGPLLVICLCYLLIVVKVRSSGRRVRALSSKHKLSERRVTRMVVTVVAVFVLCWLPFYVLNIINVVCPLPEEPSLFGVYFLVVVLPYANSCANPIIYGFLSYRFKQGFRRAIFRPSRRVQSQEVPECPPEKSDDGGEEKEISKITQNGNDREERPLSSRAGERNGQKPLPEEPVGCEKSSKLHVSYL", "length": 402, "header": "tr|A0A8V0YHV2-1|A0A8V0YHV2_CHICK Isoform 1 of Somatostatin receptor 3 OS=Gallus gallus OX=9031 GN=SSTR3 PE=3 SV=1 CANONICAL=A0A8V0YHV2-1" }, "locus": { "chromosome": "1", "start_pos": 51470833, "end_pos": 51469628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035048.1", "url": "https://www.ensembl.org/id/ENSGALT00010035048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020469.1", "url": "https://www.ensembl.org/id/ENSGALP00010020469.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427907", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TC77-1", "protein_name": "Somatostatin receptor 3", "gene_name": "SSTR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTPGSLSLLPVTSEPGNTSSAWPPDAVLGNVSAASSAAGLAVSGILIPLVYLVVCVVGLLGNSLVIYVVLRQTATPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVRAPSCQRRRHSERKVTRMVVAVVALFVLCWMPFYVLNIINVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVQNQEPPVGPPEKTEEEEEAGDGEDRHEGAGKQGDWGEMNGRVNQIIQPGPSGQERPPSSTTSKERQFLPQEPLAGEKSDTLHISYL", "length": 422 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IM09-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "Sstr3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASAAYASSVPTTLDPGNTSSAWPLDASLGNASAGTSLAGLAVSGILISLVYLVVCVVGLLGNSLVICVVLRHTASPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAAFIIYTAALGFFGPLLIICLCYLLIVVKVRSATRRVRAPSCQWVQASSCQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIINVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSGPPEKTEEEEEEEEEERREEEERRSRRKEMNGRAGQIAQPGTSGQEPSTGTAKEQQFLPQEATAGDKPGTLSHL", "length": 425 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LL93-1", "protein_name": "Somatostatin receptor 3", "gene_name": "SSTR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTPGYPSLVPTTSEPGNASSAWSLDAVLGNGSSAPSAAGLAVRGILIPLVYLVVCVVGLLGNSLVIYVVLRQTASPSVTSIYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVRAPSCQRRRPSERRVTRMVVAVVALFVLCWMPFYVLNIINVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRNQEPPVGPPEKTEEEEEDGGEHEKGGAGNQGERKEMNGRVIQITQPGPSGQERPPSGTATKEHQFLPQEPSAGDKSGPLHISYL", "length": 421 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P30935-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "Sstr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVTYPSSEPTTLDPGNASSTWPLDTTLGNTSAGASLTGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRIRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQAGTSGQQPRPCTGTAKEQQLLPQEATAGDKASTLSHL", "length": 428 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P30936-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "Sstr3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVTYPSSVPTTLDPGNASSAWPLDTSLGNASAGTSLAGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQPGPSGQQQRPCTGTAKEQQLLPQEATAGDKASTLSHL", "length": 428 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32745-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "SSTR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL", "length": 418 }, "evidence": [ { "id": "A0A8V0YHV2", "url": "https://omabrowser.org/oma/group/A0A8V0YHV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "somatostatin receptor activity", "id": "GO:0004994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004994", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "neuropeptide binding", "id": "GO:0042923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 312, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", 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"locus": {} } ], "crossref": [ { "id": "A0A8V0YHV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHV7", "url": "https://www.orthodb.org/?gene=A0A8V0YHV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12348:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12348:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QSWREKGKSRLSAGLCACTPASRELGVRPSPFIRGSRPPYSWSGEPASPPCTQHGLPKGECYPWVWRWGVGVPLGAKSCVPIAVGRPGLEFGGAASRACTPTGVVLCATWWAESASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEVLKEQIKELLEKNSQLERENSLLKTLASPEQLEKFQSRLPSEVLHPQEQSPGAAPPAQHSGGSAV", "length": 212, "header": "tr|A0A8V0YHV7-1|A0A8V0YHV7_CHICK Isoform 1 of TSC22 domain family protein 3 OS=Gallus gallus OX=9031 GN=TSC22D4 PE=3 SV=1 CANONICAL=A0A8V0YHV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7/entry", "sequence": { "sequence": "QSWREKGKSRLSAGLCACTPASRELGVRPSPFIRGSRPPYSWSGEPASPPCTQHGLPKGECYPWVWRWGVGVPLGAKSCVPIAVGRPGLEFGGAASRACTPTGVVLCATWWAESASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEVLKEQIKELLEKNSQLERENSLLKTLASPEQLEKFQSRLPSEVLHPQEQSPGAAPPAQHSGGSAV", "length": 212, "header": "tr|A0A8V0YHV7-1|A0A8V0YHV7_CHICK Isoform 1 of TSC22 domain family protein 3 OS=Gallus gallus OX=9031 GN=TSC22D4 PE=3 SV=1 CANONICAL=A0A8V0YHV7-1" }, "locus": { "chromosome": "4", "start_pos": 1749912, "end_pos": 1746157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035061.1", "url": "https://www.ensembl.org/id/ENSGALT00010035061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020472.1", "url": "https://www.ensembl.org/id/ENSGALP00010020472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7" } ], "pmid": "" }, { "name": "negative regulation of activation-induced cell death of T cells", "id": "GO:0070236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YHY0-1", "uniprot_ac": "A0A8V0YHY0", "uniprot_id": "A0A8V0YHY0_CHICK", "mass": { "chemical_mass": 41298.0, "monoisotopic_mass": 41298.0 }, "refseq": { "ac": "XP_015154922", "name": "carbonyl reductase [NADPH] 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922" }, "gene_names": [ { "name": "CBR3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0" } ] }, { "name": "CBR1", "type": "synonym", "evidence": [ { "id": "XP_015154922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922" } ] }, { "name": "CBR3", "type": "synonym", "evidence": [ { "id": "XP_015154922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922" } ] } ], "protein_names": [ { "name": "carbonyl reductase (NADPH)", "type": "recommended", "evidence": [ { "id": "A0A8V0YHY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.184", "type": "synonym", "evidence": [ { "id": "A0A8V0YHY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0/entry#names_and_taxonomy" } ] }, { "name": "carbonyl reductase [NADPH] 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015154922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154922.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0", "locus": { "chromosome": "1", "start_pos": 106673668, "end_pos": 106664804, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012964", "url": "https://www.ensembl.org/id/ENSGALG00010012964" } ] } } ], "crossref": [ { "id": "A0A8V0YHY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05324", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05324", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418512", "url": "https://www.ncbi.nlm.nih.gov/gene/418512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHX5", "url": "https://www.orthodb.org/?gene=A0A8V0YHX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHY0", "url": "https://www.orthodb.org/?gene=A0A8V0YHY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPP9", "url": "https://www.orthodb.org/?gene=A0A8V0YPP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43963:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43963:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2162123", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2162123", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015154922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGEYHFPPAPDSLQRERESIDGHAIPRKTHLAKRKNKPPLPLPSPTRPAPAAAGGGAARRHFRCARLPPRCAQLLLVGRPFPALRSAGSDCCFGIHPEKIMSNVPVAVVTGSNKGIGLAIVRDLCKQFKGDVYLTARDPARGQEAVAKLQEEGLHPLFHQLDIDDLQSIKVLRDFLKEKYGGLNVLVNNAGIAFKVSDRTPFAVQAEVTLKTNFFGTRNICTELLPLIKPYGRVVNVSSMVSISALGGCSQELQKKFRSDTITEDELVELMTKFVEDTKKSVHEKEGWPNTAYGVSKIGVTVLSRIQARMLNEKRKGDHILLNACCPGWVRTDMAGPKAPKSPEEGAETPVYLALLPSDADGPHGQFVSEKTVRTW", "length": 377, "header": "tr|A0A8V0YHY0-1|A0A8V0YHY0_CHICK Isoform 1 of carbonyl reductase (NADPH) OS=Gallus gallus OX=9031 GN=CBR3 PE=1 SV=1 CANONICAL=A0A8V0YHY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX5/entry", "sequence": { "sequence": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

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}, { "id": "A0A8V0YI53", "url": "https://www.orthodb.org/?gene=A0A8V0YI53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQS9", "url": "https://www.orthodb.org/?gene=A0A8V0YQS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19300:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19300:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022854", "url": 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"A0A8V0YI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWPRGPRGAWRLLPRRSLLAVLFLFSLSSSFLYFVYVAPGIVNTYLFMMQAQGIMIRENMRTIGAQVYEQVVRSAYAKRNSSVNDSDYPLDLNHNETFLQATTFLPEDFTYFPNHTCPERLPSMKGPIDVNMSEITMEDIHQFFSRDPSIKLGGHWKPSDCLPRWKVAILIPFRNRYEHLPVLFRHLIPMLQRQRLQFAFYVVEQAGTQPFNRAMLFNVGFREAMKDLDWDCLIFHDVDHIPENDRNYYGCGQMPRHFAAKLDKYMYLLPYNEFFGGVSGLTVEQFWKINGFPNAFWGWGGEDDDLWNRVQYAGYSVTRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQALDGLNNLNYFPNVTYDALYKNITVNLTPELALVTEY", "length": 392, "header": "tr|A0A8V0YI53-1|A0A8V0YI53_CHICK Isoform 1 of Beta-1,4-galactosyltransferase OS=Gallus gallus OX=9031 GN=B4GALT5 PE=3 SV=1 CANONICAL=A0A8V0YI53-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI46/entry", "sequence": { "sequence": "MFARCLWALKQQQQINKAYRINQENKYCSATVNTYLFMMQAQGIMIRENMRTIGAQVYEQVVRSAYAKRNSSVNDSDYPLDLNHNETFLQATTFLPEDFTYFPNHTCPERLPSMKGPIDVNMSEITMEDIHQFFSRDPSIKLGGHWKPSDCLPRWKVAILIPFRNRYEHLPVLFRHLIPMLQRQRLQFAFYVVEQAGTQPFNRAMLFNVGFREAMKDLDWDCLIFHDVDHIPENDRNYYGCGQMPRHFAAKLDKYMYLLPYNEFFGGVSGLTVEQFWKINGFPNAFWGWGGEDDDLWNRVQYAGYSVTRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQALDGLNNLNYFPNVTYDALYKNITVNLTPELALVTEY", "length": 381, "header": "tr|A0A8V0YI46-1|A0A8V0YI53_CHICK Computationally mapped isoform of Beta-1,4-galactosyltransferase OS=Gallus gallus OX=9031 GN=B4GALT5 PE=3 SV=1 CANONICAL=A0A8V0YI53-1" }, "locus": { "chromosome": "20", "start_pos": 14229028, "end_pos": 14212507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031665.1", "url": "https://www.ensembl.org/id/ENSGALT00010031665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018525.1", "url": "https://www.ensembl.org/id/ENSGALP00010018525.1" } ] } }, { "isoform_ac": "A0A8V0YI53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53/entry", "sequence": { "sequence": "MRWPRGPRGAWRLLPRRSLLAVLFLFSLSSSFLYFVYVAPGIVNTYLFMMQAQGIMIRENMRTIGAQVYEQVVRSAYAKRNSSVNDSDYPLDLNHNETFLQATTFLPEDFTYFPNHTCPERLPSMKGPIDVNMSEITMEDIHQFFSRDPSIKLGGHWKPSDCLPRWKVAILIPFRNRYEHLPVLFRHLIPMLQRQRLQFAFYVVEQAGTQPFNRAMLFNVGFREAMKDLDWDCLIFHDVDHIPENDRNYYGCGQMPRHFAAKLDKYMYLLPYNEFFGGVSGLTVEQFWKINGFPNAFWGWGGEDDDLWNRVQYAGYSVTRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQALDGLNNLNYFPNVTYDALYKNITVNLTPELALVTEY", "length": 392, "header": "tr|A0A8V0YI53-1|A0A8V0YI53_CHICK Isoform 1 of Beta-1,4-galactosyltransferase OS=Gallus gallus OX=9031 GN=B4GALT5 PE=3 SV=1 CANONICAL=A0A8V0YI53-1" }, "locus": { "chromosome": "20", "start_pos": 14229028, "end_pos": 14204911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031671.1", "url": "https://www.ensembl.org/id/ENSGALT00010031671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018530.1", "url": "https://www.ensembl.org/id/ENSGALP00010018530.1" } ] } }, { "isoform_ac": "A0A8V0YQS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS9/entry", "sequence": { "sequence": "MRWPRGPRGAWRLLPRRSLLAVLFLFSLSSSFLYFVYVAPGIVNTYLFMMQAQGIMIRENMRTIGAQVYEQVVRSAYAKRNSSVNDSEGPIDVNMSEITMEDIHQFFSRDPSIKLGGHWKPSDCLPRWKVAILIPFRNRYEHLPVLFRHLIPMLQRQRLQFAFYVVEQAGTQPFNRAMLFNVGFREAMKDLDWDCLIFHDVDHIPENDRNYYGCGQMPRHFAAKLDKYMYLLPYNEFFGGVSGLTVEQFWKINGFPNAFWGWGGEDDDLWNRVQYAGYSVTRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQALDGLNNLNYFPNVTYDALYKNITVNLTPELALVTEY", "length": 354, "header": "tr|A0A8V0YQS9-1|A0A8V0YQS9_CHICK Computationally mapped isoform of Beta-1,4-galactosyltransferase OS=Gallus gallus OX=9031 GN=B4GALT5 PE=3 SV=1 CANONICAL=A0A8V0YI53-1" }, "locus": { "chromosome": "20", "start_pos": 14229028, "end_pos": 14204911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031667.1", "url": "https://www.ensembl.org/id/ENSGALT00010031667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018527.1", "url": "https://www.ensembl.org/id/ENSGALP00010018527.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:107054826", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054826", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" }, { "id": "R-GGA-975577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975577", "resource": "Reactome", "description": "N-Glycan antennae elongation" }, { "id": "R-GGA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3K5-1", "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4galt5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRARRGLLRLPRRSLLAALFFFSLSSSLLYFVYVAPGIVNTYLFMVQAQGILLRDNVRTIGAQVYEQVVRSAYAKRNSSLNDSDYPLDLNHSEAFPPTTTFLPEDFTYFANHPCPERLPSMKGPIDINMSEIRMDDIHELFSRDPAIRLGGHWKPADCMPRWKVAILIPFRNRHEHLPVLLRHLLPMLQRQRLQFAFYVIEQAGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQGLDGLNNLSYSANVTYDALYKNITVNLTPELAQVTEY", "length": 388 }, "evidence": [ { "id": "A0A8V0YI53", "url": "https://omabrowser.org/oma/group/A0A8V0YI53/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9T0M7-1", "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4GALT5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTYLFMMQAQGILIRDNMRTIGAQVYEQVVRSAYAKRNSSVNDSDYPLDLNHSESFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDAIHELFSKDPTIKLGGHWKPSDCVPRWKVAILVPFRNRHEHLPVLLRHLIPMLQRQRLRFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQAVDGLNNLNYFANVTYDALYKNITVNLTPELAQVTEY", "length": 350 }, "evidence": [ { "id": "A0A8V0YI53", "url": "https://omabrowser.org/oma/group/A0A8V0YI53/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43286-1", "protein_name": "Beta-1,4-galactosyltransferase 5", "gene_name": "B4GALT5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRARRGLLRLPRRSLLAALFFFSLSSSLLYFVYVAPGIVNTYLFMMQAQGILIRDNVRTIGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKLGGHWKPSDCMPRWKVAILIPFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQGLDGLNNLNYFANITYDALYKNITVNLTPELAQVNEY", "length": 388 }, "evidence": [ { "id": "A0A8V0YI53", "url": "https://omabrowser.org/oma/group/A0A8V0YI53/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMK0-1", "protein_name": "Beta-1,4-galactosyltransferase 5", "gene_name": "B4galt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRARRGLLRLPRRSLLAALFFFSLSSSLLYFVYVAPGIVNTYLFMVQAQGILLRDNVRTIGAQVYEQVVRSAYAKRNSSLNDSDYPLDLNHSEAFPPTTTFLPEDFTYFANHPCPERLPSMKGPIDINMSEIAMDDIHELFSRDPAIKLGGHWKPADCVPRWKVAILIPFRNRHEHLPVLLRHLLPMLQRQRLQFAFYVIEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQGLDGLNNLNYSANVTYDALYKNITVNLTPELAQVTEY", "length": 388 }, "evidence": [ { "id": "A0A8V0YI53", "url": "https://omabrowser.org/oma/group/A0A8V0YI53/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity", "id": "GO:0008489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008489", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "N-acetyllactosamine synthase activity", "id": "GO:0003945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "central nervous system myelination", "id": "GO:0022010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "positive regulation of embryonic development", "id": "GO:0040019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "central nervous system neuron axonogenesis", "id": "GO:0021955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" }, { "name": "neuron maturation", "id": "GO:0042551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042551", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "31495", "name": "", "equation": "a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "31495", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31495" } ] }, { "id": "R-GGA-1964501", "name": "Addition of galactose to Core 6 glycoprotein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "R-GGA-1964501", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1964501" } ] }, { "id": "R-GGA-2025723", "name": "B4GALTs transfer Gal to the N-glycan precursor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V1A4L8-1", "A0A8V1A5K9-1", "A0A1D5PSH8-1", "A0A8V0Y298-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "R-GGA-2025723", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2025723" } ] }, { "id": "R-GGA-2046265", "name": "B4GALTs transfer Gal to the keratan chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V1A4L8-1", "A0A8V1A5K9-1", "A0A1D5PSH8-1", "A0A8V0Y298-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "R-GGA-2046265", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2046265" } ] }, { "id": "R-GGA-2046298", "name": "B4GALTs transfer Gal to a branch of keratan", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V1A4L8-1", "A0A8V1A5K9-1", "A0A1D5PSH8-1", "A0A8V0Y298-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "R-GGA-2046298", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2046298" } ] }, { "id": "R-GGA-975919", "name": "Addition of galactose by beta 4-galactosyltransferases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-981618" ], "enzyme_list": [ "A0A3S5ZPV4-1", "A0A8V1A4L8-1", "A0A8V1A5K9-1", "A0A1D5PSH8-1", "A0A8V0Y298-1", "A0A8V0YI53-1" ], "evidence": [ { "id": "R-GGA-975919", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975919" } ] }, { "id": "R-GGA-9851347", "name": "B4GALT5/6 transfer Gal to GlcCer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV4" } ] } ] }, { "uniprot_ac": "A0A8V0Y298", "gene_name": "B4GALT1", "activity": [ { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] }, { "ec_number": "2.4.1.90", "activity": "", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] } ] }, { "uniprot_ac": "A0A8V0YI53", "gene_name": "B4GALT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YI53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI53" } ] } ] }, { "uniprot_ac": "A0A8V1A4L8", "gene_name": "B4GALT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V1A4L8", "database": "UniProtKB", "url": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YI49-1", "uniprot_ac": "A0A8V0YI49", "uniprot_id": "A0A8V0YI49_CHICK", "mass": { "chemical_mass": 69274.0, "monoisotopic_mass": 69274.0 }, "refseq": {}, "gene_names": [ { "name": "LACAAT2L", "type": "recommended", "evidence": [ { "id": "A0A8V0YI49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI49" } ] } ], "protein_names": [ { "name": "Cationic amino acid transporter C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YI49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI49" } ], 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"XP_001233592", "name": "28S ribosomal protein S15, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233592" }, "gene_names": [ { "name": "MRPS15", "type": "recommended", "evidence": [ { "id": "A0A8V0YI69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ] }, { "name": "MRPS15", "type": "synonym", "evidence": [ { "id": "XP_001233592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233592" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS15m", "type": "recommended", "evidence": [ { "id": "A0A8V0YI69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S15, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_001233592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233592" }, { "id": "A0A8V0YI69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233592.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPS15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69", "locus": { "chromosome": "23", "start_pos": 4388227, "end_pos": 4381189, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014729", "url": "https://www.ensembl.org/id/ENSGALG00010014729" } ] } } ], "crossref": [ { "id": "A0A8V0YI69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI69", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00353", 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Computationally mapped isoform of Small ribosomal subunit protein uS15m OS=Gallus gallus OX=9031 GN=MRPS15 PE=3 SV=1 CANONICAL=A0A8V0YI69-1" }, "locus": { "chromosome": "23", "start_pos": 4387502, "end_pos": 4381241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035376.1", "url": "https://www.ensembl.org/id/ENSGALT00010035376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020588.1", "url": "https://www.ensembl.org/id/ENSGALP00010020588.1" } ] } }, { "isoform_ac": "A0A8V0YI69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69/entry", "sequence": { "sequence": "MLALGRGLAGAARGALTALRVGRGAAGAACSPFIQTARCYARPVRRKLKDIPSHLDDLPPTMLKKDYASIPVINSVDDVVKRLLSLEMANQRDKMKIKIQQLVEKVRRSPSDNGSFEVQTAILTAKIRTFEEHLHRHPKDKNNRRRMLMAMDRRNKLLAYLRRVRYDVFENTCKQLNIQYTPRPAYSRRVTKRWVVKKAFCVKVFQEARKLKAAERQKERRKWQERARAAKEKQAQSEGTPV", "length": 242, "header": "tr|A0A8V0YI69-1|A0A8V0YI69_CHICK Isoform 1 of Small ribosomal subunit protein uS15m OS=Gallus gallus OX=9031 GN=MRPS15 PE=3 SV=1 CANONICAL=A0A8V0YI69-1" }, "locus": { "chromosome": "23", "start_pos": 4387502, "end_pos": 4381241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035382.1", "url": "https://www.ensembl.org/id/ENSGALT00010035382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020593.1", "url": "https://www.ensembl.org/id/ENSGALP00010020593.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770261", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5H1ZRH5-1", "protein_name": "Small ribosomal subunit protein uS15m", "gene_name": "MRPS15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRAAWRALSSIRTQAVTQPPVLGLPGGGCAKLLSVQRDLPSSPGGLILQAARGYATQKPVQQSQEDDPPPSMLLKDYQNVPGIEKVDDVVKRLISLEMANKKEMLKIKKEQLMSKVVENPKDTSSLEAQIVALTVKIRSYEEHMQKHQKDKAHKRYLLMSIDKRQKMLKNLRKTNYPVFEKTCKELGIEYTFPPPYHRKIHRRLATKKALCIRVFQEVQKLKKQKRALKTAAAAVQKQGQRNPESPSEARSEAIKETQ", "length": 259 }, "evidence": [ { "id": "A0A8V0YI69", "url": "https://omabrowser.org/oma/group/A0A8V0YI69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A9J7GMX5-1", "protein_name": "Small ribosomal subunit protein uS15m", "gene_name": "Mrps15", "tax_id": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIA2-1", "uniprot_ac": "A0A8V0YIA2", "uniprot_id": "A0A8V0YIA2_CHICK", "mass": { "chemical_mass": 69263.0, "monoisotopic_mass": 69263.0 }, "refseq": { "ac": "XP_040511567", "name": "recQ-mediated genome instability protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511567" }, "gene_names": [ { "name": "RMI1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ] }, { "name": "RMI1", "type": "synonym", "evidence": [ { "id": "XP_040511567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511567" } ] } ], "protein_names": [ { "name": "RecQ-mediated genome instability protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2/entry#names_and_taxonomy" } ] }, { "name": "recQ-mediated genome instability protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040511567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511567" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511567" } ] }, { "annotation": "Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2#function" }, { "database": "UniProtKB", "id": "ARBA00024977", "url": "https://www.uniprot.org/uniprotkb/ARBA00024977#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2", "locus": { "chromosome": "Z", "start_pos": 40707695, "end_pos": 40702151, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014737", "url": "https://www.ensembl.org/id/ENSGALG00010014737" } ] } } ], "crossref": [ { "id": "431669", "url": "https://www.ncbi.nlm.nih.gov/gene/431669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SATWHVK", "url": "https://omabrowser.org/oma/group/SATWHVK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIA2", "url": "https://www.orthodb.org/?gene=A0A8V0YIA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14790", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14790", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14790:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14790:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5685938", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693579", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTPNVTARVETWLSSTWHVKVPLTWLEACINWIQEENGGGNLSQAQINRQVFEQWLLTDLRDLEYPILPDGILDAPKGELSGFYSLQIDSLLDVSQPAYSQLQKIRGKSTVNEEVTANTQAFQKPWEAKPTRMLMLQLTDGIHQIQGMEYQPVPVLHSNLPPGTKITVHGNVAYRLGVLLLKPENVKLLGGEVDALLEEYSQERVLARLLGEAENPDSVRQPGHEQIVPGPVDELGQTLGPSDEELLASLDENNDFILNNETSLESGYCSRSNNFSATSCSLTTYNENTTGFPLQQESVNLLPRSDEQTPPSVEYNDAFLNDFPLEDDILLEEEIQRELEEVPSVARNGNVNLSTERIPHTYRSSCGSSLNETSEKDDGCGSEKPVEVTSKQKNLARTVSTGDGTSTGGSLQCNSVSQACSSAIVLLKNPHEERRNDLGPDESSCQSRHAPDSRQLNKDPVSSSKTDPEADQQAILCRPGNACDLDLDSPPFTYISLLLAKKPETITLVKVKCFIVTLTGNLTSSNGSWGIKAKVSDGSAYLEVDFADDILTSLIGFSVPEMHTLRKDPALQPKLKDGLERCQKQLIDLCCLMTIEFNPFQSKATVLILQDTDARHLEQLKKRLNK", "length": 627, "header": "tr|A0A8V0YIA2-1|A0A8V0YIA2_CHICK Isoform 1 of RecQ-mediated genome instability protein 1 OS=Gallus gallus OX=9031 GN=RMI1 PE=3 SV=1 CANONICAL=A0A8V0YIA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2/entry", "sequence": { "sequence": "MSTPNVTARVETWLSSTWHVKVPLTWLEACINWIQEENGGGNLSQAQINRQVFEQWLLTDLRDLEYPILPDGILDAPKGELSGFYSLQIDSLLDVSQPAYSQLQKIRGKSTVNEEVTANTQAFQKPWEAKPTRMLMLQLTDGIHQIQGMEYQPVPVLHSNLPPGTKITVHGNVAYRLGVLLLKPENVKLLGGEVDALLEEYSQERVLARLLGEAENPDSVRQPGHEQIVPGPVDELGQTLGPSDEELLASLDENNDFILNNETSLESGYCSRSNNFSATSCSLTTYNENTTGFPLQQESVNLLPRSDEQTPPSVEYNDAFLNDFPLEDDILLEEEIQRELEEVPSVARNGNVNLSTERIPHTYRSSCGSSLNETSEKDDGCGSEKPVEVTSKQKNLARTVSTGDGTSTGGSLQCNSVSQACSSAIVLLKNPHEERRNDLGPDESSCQSRHAPDSRQLNKDPVSSSKTDPEADQQAILCRPGNACDLDLDSPPFTYISLLLAKKPETITLVKVKCFIVTLTGNLTSSNGSWGIKAKVSDGSAYLEVDFADDILTSLIGFSVPEMHTLRKDPALQPKLKDGLERCQKQLIDLCCLMTIEFNPFQSKATVLILQDTDARHLEQLKKRLNK", "length": 627, "header": "tr|A0A8V0YIA2-1|A0A8V0YIA2_CHICK Isoform 1 of RecQ-mediated genome instability protein 1 OS=Gallus gallus OX=9031 GN=RMI1 PE=3 SV=1 CANONICAL=A0A8V0YIA2-1" }, "locus": { "chromosome": "Z", "start_pos": 40705554, "end_pos": 40703674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035420.1", "url": "https://www.ensembl.org/id/ENSGALT00010035420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020616.1", "url": "https://www.ensembl.org/id/ENSGALP00010020616.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-5693579", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "resource": "Reactome", "description": "Homologous DNA Pairing and Strand Exchange" }, { "id": "R-GGA-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-GGA-5693616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "resource": "Reactome", "description": "Presynaptic phase of homologous DNA pairing and strand exchange" } ], "orthologs": [ { "uniprot_canonical_ac": "A4IF98-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVTSIALRVETWLSATWHVKVPVTWLEACINWIQEENDHVNLSQAQMNKQVFEQWLLTDLRDLEHRLLPSGILETPKGELNGFFALQINSLVDVSQPAYAQIQKLRGKNTTNDLITAETQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQSIPALHSDLPPGTKILIYGNISFRLGVLLLKPENVKMLGGEVDALLEEYAQEKVLARLIGEPDPIVSVIPNNSNQIIPRITDVLDPALGPSDEELLASLDENDELAANNNTSLERSCFIGNSSNTVPIRQSDFETELVISPRPREKPRNQSMLFTDEELDDFSLEEALLLEEAVQKEQMETKELQLLTLNRTTDESIEKFSHRSNTLNNFSFICKNGNNNWSEKNLSEQMTSEDKSLSCPSTRDQNSSSLSVNHNVPLPHDFTNKGKSSETYKIKQISSSDGHSLNNKMFNGELVSNVPKRSSDVPNENEHHLQTCSLQLSENSTGLPITMDLYSPPFIYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSVRAKISDGTAYLDVDFVDEILTSLIGFSVSEMKRLKKDPCKYQKFLEGLQKCQRELIDLCCLMTISFNPSLSKAMVLALQDVNTDHLENLKRRLKK", "length": 624 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZHX4-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "Rmi1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVASAVLRVETWLLATWNIKVPLMWLEACVNWIQEENNSANLSQAQINKQVLEQWLLTDLRDLEHPLLPDDILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKSTTNDLVSAETQTAPEPWQVRPSRMLMLQLTDGVTQVQGMEYQSIPALHSALPPGTKILVHGHILFRLGVLLLKAENVKVLGGEVDGLAEEYAQEKILARLIGEPDPTVSVIPNNSNPSAPRVSGDLDAALGPSDEELLASLDESEEPAASDDVTVGRLSFSTGPSSDTAPTIQTGFEPGCNISSRPKEKLPNQPVHFTDGEFDDFSLEEALLLEETVQKEKMEAKASQPLSLKESVGKRVEEAFSPRPGGLNHTASTHKQGNSHFSEKTSEQMIHEDTLFDCSSTRHHRKRLLAHDFTKDSKISEVDDVAQQTTNSSDVHCLSNKMLNRKPDLSEKSSQHSKGNGHPFQTCSSRSFENNTNLSIGMDLHCPPFIYLSVLMARKPKEVTTVKVKAFIVTLTGNLSSSGGFWCVTAKVSDGTAYLDVDFIDEILTSMIGYSVPEMKQLKKDPLKYKKFLEGLQKCQRDLIDLCCLMTVSYDPSSCKGMVLELQDVGVEHLENLKKRLNK", "length": 617 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S4G5-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVTSIASRVETWLLATWHVKVPLMWLEACINWIQEENDNVNLSQAQMNKQVFEQWLLTDLRDLEYPLLPDGILEVPKGELNGFFALQIISLVDVSQPAYAQIQKLRGKNTSNDLITAETQVVPKPWEAKPSRMLMLQLTDGIVQIQGMEYHSIPALHSDLPPGTKILIYGNISFRLGVLLLKPENVKVLGGEVDALLEEYAPQRVLARLIGEPDPTVSVIPNNSNQSIPRITDVLDPTLGPSDEELLASLDESDELAANNASLERSCFSTGSSSNAIPTTQLDFEPGLISPRPKERPQNQSMPFTDGELDDFSLEEALLLEEAVQKEQMETKELQPMTLNRTPDESIERFSHRSNTLNNFSLICKNGNNWNKKNLSEQMTNEDKSFSCPSARDRNSSTFSVNHNVPLPHDFTNEDKNSEPYNEIEQASSSGEHSFNNKILNGELVSYVPKKSGDISNENERHLQSCSLRSSENSTNLSVTMDLYSPPFIYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKISDGTAYLDVGFVHEILFSLIGFSVPEMKQLKKDPCKYQKFREGLQKCQRDLIDLCCLMTISFDPCLSKAMVLALQDVNMEHLENLKRRLKK", "length": 623 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IAT0-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "Rmi1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVNSAVLRVETWLLATWHVKVPLTWLEACVNWIQEENDNTSLSQAQVNKQVLEQWLLTDLRDLEHPLLPDNILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVSAETQITPKPWEARPSRMLMLQLTDGVTQIQGMEYQSIPALHGGLPPGTKILVHGRISFRLGVLLLKPENVKVLGGEVDGLSEEYAQEKVLGRLIGELDPTVSVVPNNSDHSMSRVSGGLDPALGPSDEELLASLYESEEPAANNDASTGGSCFSTGSSLNTTSTGQSDFEPGYSISSRQKEKPNQSVHFTDGEFDDFSLEEALLLEETVQKEQMETKALQPPTLKKNTDKRGEIFSHKPNTQNHTALIRKQGNSNCNEKKLSEQIIHEDKFFGCPSARDSHKTVLAHDFTNDSKTLGVDNTKKQNINSSGEQCLSNKMLKRKQGTCLSEESSEISNENSYPLQTCSSKSFENNTDLSVGMDLHSPPFIYLAVLMARKPKEVTTVKVKAFIVTLTGNLSSSGGCWGVTAKVSDGTAYLDVDFIDEILTSMIGFSVPEMKQLKKDPLKYQNFLKGLQKCQRDLIDLCCLMTISFNPSSCKAMVLELQDVSMEHLENLKKRLKK", "length": 618 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9D4G9-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "Rmi1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVASAVLRVETWLLATWHVKVPPMWLEACVNWIQEENNNATLSQAQINKQVLEQWLLTDLRDLEHPLLPDDILELPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVSAETQSTPKPWEVRPSRMLMLQLTDGVTHIQGMEYQSIPALHSGLPPGTKILVRGCILFRLGVLLLKPENVKVLGGEVDGLSEENAQEKVLARLIGELDPTVPVIPNNSIHNVPKVSGGLDAVLGPSDEELLASLDESEESAANNDVAMERSCFSTGTSSNTTPTNPSGFEPGCNISSRPKEKPPNQPTHFTDGEFDDFSLEEALLLEETVQKEQMETKASQPLTLKENTGKCMEIFSHKPSSLNHTALIHKQGNSNFDEKTSEQMIHEDKFFDCASTRNHHKRFSAHDFTNDSKISEVDDAAQQTLSSSNVHCLRNKILNRKLDLSEKSSQISKENGHPFQACSSRSFENNTYLSIGMDLHSPPFIYLSVLMARKPKEVTTVTVKAFIVTLTGNLSSSGGFWGVTAKVSDGTAYLDVDFIDEILTSMIGYSVPEMKQLRKDPLKYKTFLEGLQKCQRDLIDLCCLMTISYDPSSCKGVVLELQDVGMEHVENLKKRLNK", "length": 616 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTDLRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEAQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVLLLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPALGPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPSNLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTNNFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKNLETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINLSIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAYLDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSLSKAMVLALQDVNMEHLENLKKRLNK", "length": 625 }, "evidence": [ { "id": "A0A8V0YIA2", "url": "https://omabrowser.org/oma/group/A0A8V0YIA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" }, { "name": "resolution of DNA recombination intermediates", "id": "GO:0071139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" }, { "name": "RecQ family helicase-topoisomerase III complex", "id": "GO:0031422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031422", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" }, { "id": "PF21000", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RMI1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 63, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" }, { "id": "PF08585", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08585" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecQ mediated genome instability protein 1 OB-fold", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 205, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA2" }, { "id": "PF16099", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16099" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecQ-mediated genome instability protein 1 C-terminal OB-fold", "eco_id": "ECO_0000259", "start_pos": 490, "end_pos": 625, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 261, "end_pos": 263 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIB2-1", "uniprot_ac": "A0A8V0YIB2", "uniprot_id": "A0A8V0YIB2_CHICK", "mass": { "chemical_mass": 49255.0, "monoisotopic_mass": 49255.0 }, "refseq": { "ac": "XP_001231894", "name": "beta-1,3-galactosyltransferase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231894" }, "gene_names": [ { "name": "B3GALT2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ] }, { "name": "B3GALT2", "type": "synonym", "evidence": [ { "id": "XP_001231894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231894" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-galactosyltransferase 2", "type": "synonym", "evidence": [ { "id": "XP_001231894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231894" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231894.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231894" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "B3GALT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2", "locus": { "chromosome": "8", "start_pos": 3472285, "end_pos": 3433998, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012618", "url": "https://www.ensembl.org/id/ENSGALG00010012618" } ] } } ], "crossref": [ { "id": "769122", "url": "https://www.ncbi.nlm.nih.gov/gene/769122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769122", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TSYHFKY", "url": "https://omabrowser.org/oma/group/TSYHFKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIB2", "url": "https://www.orthodb.org/?gene=A0A8V0YIB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9037629", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9037629", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001231894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQWRRRHCCLAKMTWNTKRSLFRTHLIGLISLVFLFAVFLFFNHHDWLPGRAGFRENPMTYTIRGFRSTKSEMNHSSLRNTWKDAVPQTLRPQIVTNPNNTDLSPQGVTGLENTLSANGSIYNEKGTGHPISYHFKYIINEPEKCQEKVPFLILLIAAEPGQVEARQAIRQTWGNESLTPGIQIVRIFLLGLSTKTNGYLQRTIQEESRQYHDIVQQEYLDTYYNLTIKTLMGMNWVASHCPSVPYVMKTDSDMFVNTEYLIHKLLKPELPPRHKYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPMPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKASRYRHRKLH", "length": 422, "header": "tr|A0A8V0YIB2-1|A0A8V0YIB2_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=B3GALT2 PE=3 SV=1 CANONICAL=A0A8V0YIB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2/entry", "sequence": { "sequence": "MLQWRRRHCCLAKMTWNTKRSLFRTHLIGLISLVFLFAVFLFFNHHDWLPGRAGFRENPMTYTIRGFRSTKSEMNHSSLRNTWKDAVPQTLRPQIVTNPNNTDLSPQGVTGLENTLSANGSIYNEKGTGHPISYHFKYIINEPEKCQEKVPFLILLIAAEPGQVEARQAIRQTWGNESLTPGIQIVRIFLLGLSTKTNGYLQRTIQEESRQYHDIVQQEYLDTYYNLTIKTLMGMNWVASHCPSVPYVMKTDSDMFVNTEYLIHKLLKPELPPRHKYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPMPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKASRYRHRKLH", "length": 422, "header": "tr|A0A8V0YIB2-1|A0A8V0YIB2_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=B3GALT2 PE=3 SV=1 CANONICAL=A0A8V0YIB2-1" }, "locus": { "chromosome": "8", "start_pos": 3457594, "end_pos": 3456329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030215.1", "url": "https://www.ensembl.org/id/ENSGALT00010030215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017541.1", "url": "https://www.ensembl.org/id/ENSGALP00010017541.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:769122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769122", "resource": "KEGG Pathway" }, { "id": "R-GGA-9037629", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9037629", "resource": "Reactome", "description": "Lewis blood group biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LED7-1", "protein_name": "Hexosyltransferase", "gene_name": "B3galt2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLQWRRRHCCFAKMTWNAKRSLFRTHLVGVLSLVFLFAMFLFFNHHDWLPGRPGFKENPVTYTFRGFRSTKSETNHSSLRNIWKDAVPQTLRPQTATNSNNTDLSPQGVTGLENTLSANGSNYNEKGTGYPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNESLAPGIQITRIFLLGISIKLNGYLQHAILEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHIPYVMKTDSDMFVNTEYLIHKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRKLH", "length": 422 }, "evidence": [ { "id": "A0A8V0YIB2", "url": "https://omabrowser.org/oma/group/A0A8V0YIB2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SAB1-1", "protein_name": "Hexosyltransferase", "gene_name": "B3GALT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQRRRRHCCFAKMSWSAKRSLFRTRLTAVLSLVFLFAMFLCFNHHDWLPGRAGFKENPVTYTLRGFRSTKSETNHSSLRNIWKETVPQTLRPQTATNSNHTDLSPQGVTGLENTLSANGSIYSEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNESLAPGIRITRIFLLGVSVKLQGHLQRAILEESRQHHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPQSPYVMKTDSDMFVNTEYLIHKLLKPDLPPRHNYFTGYLMRGYAPNRNRDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRKLH", "length": 422 }, "evidence": [ { "id": "A0A8V0YIB2", "url": "https://omabrowser.org/oma/group/A0A8V0YIB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43825-1", "protein_name": "Beta-1,3-galactosyltransferase 2", "gene_name": "B3GALT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQWRRRHCCFAKMTWNAKRSLFRTHLIGVLSLVFLFAMFLFFNHHDWLPGRAGFKENPVTYTFRGFRSTKSETNHSSLRNIWKETVPQTLRPQTATNSNNTDLSPQGVTGLENTLSANGSIYNEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNESLAPGIQITRIFLLGLSIKLNGYLQRAILEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHIPYVMKTDSDMFVNTEYLINKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRKLH", "length": 422 }, "evidence": [ { "id": "A0A8V0YIB2", "url": "https://omabrowser.org/oma/group/A0A8V0YIB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O54905-1", "protein_name": "Beta-1,3-galactosyltransferase 2", "gene_name": "B3galt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQWRRRHCCFAKMTWSPKRSLLRTPLTGVLSLVFLFAMFLFFNHHDWLPGRPGFKENPVTYTFRGFRSTKSETNHSSLRTIWKEVAPQTLRPHTASNSSNTELSPQGVTGLQNTLSANGSIYNEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNETLAPGIQIIRVFLLGISIKLNGYLQHAIQEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHTPYVMKTDSDMFVNTEYLIHKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRVDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRKLH", "length": 422 }, "evidence": [ { "id": "A0A8V0YIB2", "url": "https://omabrowser.org/oma/group/A0A8V0YIB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ], "pmid": "" }, { "name": "glucosylceramide metabolic process", "id": "GO:0006678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity", "id": "GO:0008499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-9603989", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9604808" ], "output_participant_list": [ "R-ALL-9036984" ], "enzyme_list": [ "E1BZG7-1", "E1C4T5-1", "A0A8V0X6H6-1", "A0A8V0X6I2-1", "A0A8V0YIB2-1" ], "evidence": [ { "id": "R-GGA-9603989", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603989" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9036984", "participant_name": "Type 1 chain [Golgi lumen]", "crossref": [ { "id": "140162", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9604808", "participant_name": "GlcNAc-1,3-Gal-R [Golgi lumen]", "crossref": [ { "id": "140876", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X6H6", "gene_name": "", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0X6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6H6" } ] } ] }, { "uniprot_ac": "A0A8V0X6I2", "gene_name": "", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0X6I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6I2" } ] } ] }, { "uniprot_ac": "A0A8V0YIB2", "gene_name": "B3GALT2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" } ] } ] }, { "uniprot_ac": "E1BZG7", "gene_name": "B3GALT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BZG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZG7" } ] } ] }, { "uniprot_ac": "E1C4T5", "gene_name": "B3GALT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1C4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4T5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB2" }, { "id": "PF19341", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19341" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-1,3-galactosyltransferase 2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 154, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 119, "end_pos": 121 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIC8-1", "uniprot_ac": "A0A8V0YIC8", "uniprot_id": "A0A8V0YIC8_CHICK", "mass": { "chemical_mass": 50558.0, "monoisotopic_mass": 50558.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Fork-head domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46262", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46262", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46262:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46262:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTESGRQRLEPPVPLRSRSPAPGALQMSRPPSSALETSTSSSSTSTSTSSSSSAAAATSKSKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYRMMNGLGFGASILPQGFDFQAPAASLACHSNGYNLDVMPNAVAGGYEGLGGGHHVPHMSPNPGSTYMASCPVTANGDYGPDSSSSPVPSSPAMASAIECHSPYASPSAHWTASGASPYIKQQGLPAANAAPSAIHPSVPSYSLEQGYLHQSPRDDLSGTEGDGGDPHRGLGAPPASVGRGQKRGEKREGSGLRRLGPGGGQAVRLRASLHLVLLGPLRGSRALLSRLHHGSIPGLLPSRPALPPPPPPPPPSVYTALRTAIEKRLQYSPQSAVGGKRKAHKPNPANPLTWRNATR", "length": 476, "header": "tr|A0A8V0YIC8-1|A0A8V0YIC8_CHICK Isoform 1 of Fork-head domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8/entry", "sequence": { "sequence": "MTTESGRQRLEPPVPLRSRSPAPGALQMSRPPSSALETSTSSSSTSTSTSSSSSAAAATSKSKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYRMMNGLGFGASILPQGFDFQAPAASLACHSNGYNLDVMPNAVAGGYEGLGGGHHVPHMSPNPGSTYMASCPVTANGDYGPDSSSSPVPSSPAMASAIECHSPYASPSAHWTASGASPYIKQQGLPAANAAPSAIHPSVPSYSLEQGYLHQSPRDDLSGTEGDGGDPHRGLGAPPASVGRGQKRGEKREGSGLRRLGPGGGQAVRLRASLHLVLLGPLRGSRALLSRLHHGSIPGLLPSRPALPPPPPPPPPSVYTALRTAIEKRLQYSPQSAVGGKRKAHKPNPANPLTWRNATR", "length": 476, "header": "tr|A0A8V0YIC8-1|A0A8V0YIC8_CHICK Isoform 1 of Fork-head domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIC8-1" }, "locus": { "chromosome": "2", "start_pos": 66640423, "end_pos": 66638996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027574.1", "url": "https://www.ensembl.org/id/ENSGALT00010027574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015792.1", "url": "https://www.ensembl.org/id/ENSGALP00010015792.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC8" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 168, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YID1-1", "uniprot_ac": "A0A8V0YID1", "uniprot_id": "A0A8V0YID1_CHICK", "mass": { "chemical_mass": 45280.0, "monoisotopic_mass": 45280.0 }, "refseq": { "ac": "XP_427638", "name": "terminal nucleotidyltransferase 5B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427638" }, "gene_names": [ { "name": "FAM46B", "type": "recommended", "evidence": [ { "id": "A0A8V0YID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ] }, { "name": "FAM46B", "type": "synonym", "evidence": [ { "id": "XP_427638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427638" } ] } ], "protein_names": [ { "name": "Terminal nucleotidyltransferase 5B", "type": "recommended", "evidence": [ { "id": "A0A8V0YID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "A0A8V0YID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1/entry#names_and_taxonomy" } ] }, { "name": "Non-canonical poly(A) polymerase FAM46B", "type": "synonym", "evidence": [ { "id": "A0A8V0YID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1/entry#names_and_taxonomy" } ] }, { "name": "terminal nucleotidyltransferase 5B", "type": "synonym", "evidence": [ { "id": "XP_427638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427638" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_427638.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_427638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427638" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM46B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YID1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YID1", "database": "AlphaFoldDB", "categories": [] }, { "id": "430080", "url": "https://www.ncbi.nlm.nih.gov/gene/430080", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430080", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430080", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYDCLMT", "url": "https://omabrowser.org/oma/group/RYDCLMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID1", "url": "https://www.orthodb.org/?gene=A0A8V0YID1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN63", "url": "https://www.orthodb.org/?gene=A0A8V0YN63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_427638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAAEAAGCSEQRTGERFSVLTWEQVQRLDQILGETVPIHGRGNFPTLSVRPRTIVQVVRSRLEKKGIVVHNVRLNGSAASHVLHQDSGLGYKDLDLIFGVDLKSEDVFQQVKDVVMDCLLDFLPEGVNKDKITPMTLKEAYVQKLVKVCNETDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIILDSLLLFGECSENPMAENFHPTVTGESMYGDFEEAMDHLRSRVIATRNPEEIRGGGLLKYCNLLVRGFKPKSEVDMKALQRYMCSRFFIDFSDIGEQQRKLECYLQSHFVGMEDKRYDYLMTLHRVVNESTVCLMGHERRQTLNLIATLAVRVLAEQNILPTVTNVTCYYQPAPYISEININYYVTHVQPFLPCNQSYPTWLPCN", "length": 396, "header": "tr|A0A8V0YID1-1|A0A8V0YID1_CHICK Isoform 1 of Terminal nucleotidyltransferase 5B OS=Gallus gallus OX=9031 GN=FAM46B PE=3 SV=1 CANONICAL=A0A8V0YID1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YID1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1/entry", "sequence": { "sequence": "MLAAEAAGCSEQRTGERFSVLTWEQVQRLDQILGETVPIHGRGNFPTLSVRPRTIVQVVRSRLEKKGIVVHNVRLNGSAASHVLHQDSGLGYKDLDLIFGVDLKSEDVFQQVKDVVMDCLLDFLPEGVNKDKITPMTLKEAYVQKLVKVCNETDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIILDSLLLFGECSENPMAENFHPTVTGESMYGDFEEAMDHLRSRVIATRNPEEIRGGGLLKYCNLLVRGFKPKSEVDMKALQRYMCSRFFIDFSDIGEQQRKLECYLQSHFVGMEDKRYDYLMTLHRVVNESTVCLMGHERRQTLNLIATLAVRVLAEQNILPTVTNVTCYYQPAPYISEININYYVTHVQPFLPCNQSYPTWLPCN", "length": 396, "header": "tr|A0A8V0YID1-1|A0A8V0YID1_CHICK Isoform 1 of Terminal nucleotidyltransferase 5B OS=Gallus gallus OX=9031 GN=FAM46B PE=3 SV=1 CANONICAL=A0A8V0YID1-1" }, "locus": { "chromosome": "23", "start_pos": 2230806, "end_pos": 2227018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030275.1", "url": "https://www.ensembl.org/id/ENSGALT00010030275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017561.1", "url": "https://www.ensembl.org/id/ENSGALP00010017561.1" } ] } }, { "isoform_ac": "A0A8V0YN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN63/entry", "sequence": { "sequence": "MVLRVIPACCLLSNRANDSASYSMDKALQVVRSRLEKKGIVVHNVRLNGSAASHVLHQDSGLGYKDLDLIFGVDLKSEDVFQQVKDVVMDCLLDFLPEGVNKDKITPMTLKEAYVQKLVKVCNETDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIILDSLLLFGECSENPMAENFHPTVTGESMYGDFEEAMDHLRSRVIATRNPEEIRGGGLLKYCNLLVRGFKPKSEVDMKALQRYMCSRFFIDFSDIGEQQRKLECYLQSHFVGMEDKRYDYLMTLHRVVNESTVCLMGHERRQTLNLIATLAVRVLAEQNILPTVTNVTCYYQPAPYISEININYYVTHVQPFLPCNQSYPTWLPCN", "length": 368, "header": "tr|A0A8V0YN63-1|A0A8V0YN63_CHICK Computationally mapped isoform of Terminal nucleotidyltransferase 5B OS=Gallus gallus OX=9031 GN=FAM46B PE=3 SV=1 CANONICAL=A0A8V0YID1-1" }, "locus": { "chromosome": "23", "start_pos": 2228750, "end_pos": 2227018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030271.1", "url": "https://www.ensembl.org/id/ENSGALT00010030271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017559.1", "url": "https://www.ensembl.org/id/ENSGALP00010017559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:430080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430080", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BNK8-1", "protein_name": "Terminal nucleotidyltransferase 5B", "gene_name": "Tent5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPSESGDESLEQPAAQVGTGAASAVATAGAAGGGPDLEASSASLGRHQSRLSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEQGLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMDLQSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKVCTDLDRWSLISLSNKSGKNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQCSSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDPVEQRRILERYLEAHFGGAEAARRYACLVTLHRVVNESTVCLMSHERRQTLDLITMLALQALAEQGPAAMAALAWRRPGSDGVVPATVNYYVTPMQPLLPRAHSYPTWLPCN", "length": 427 }, "evidence": [ { "id": "A0A8V0YID1", "url": "https://omabrowser.org/oma/group/A0A8V0YID1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ], "pmid": "" }, { "name": "negative regulation of cell cycle", "id": "GO:0045786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID1", "url": 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"A0A8V0YIN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10314", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10314", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN4", "url": "https://www.orthodb.org/?gene=A0A8V0YIN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN9", "url": "https://www.orthodb.org/?gene=A0A8V0YIN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNH5", "url": "https://www.orthodb.org/?gene=A0A8V0YNH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEERATAPPRRLLSKTCIQTGSSKAPGARRRVPFPGEAICSPLPGSFCMACSSPALREALLLLATLFARGKGKETRCWLDLGLLEMSAGGGFQATVVPRGHGEPGTPYSCCPRGLDGASMGLVWRAARVRGCRTALPDFCPEERRGSGCTDSLCPVWVPAPRQGRMRLQLQTLVQRKFKVLLLLLLLLALLLHVTMDLALPATRRPCSSDAKEPKASGTSTGSPLLASPEKLSLRILQDFSGSNGSLEKSSQPQGAGPKGKDGDVGIQHRHGDVGPAWAKGSKLAALFEHPLYNIPLPEVKDKDKLFIANPMEKFSLRSSRSDEWVSSSKAEMVLPTGKTAYDTYPAWLKFHIGINRYELYPRRDPLMPTLLQDLATMKIVSSVQKSGGTQLKLIMTFSNYGQALFKPMKQSRNQETPADFFYFSDFERHNAEIAAFHLDRILDFRRIPPVSGRLVNITKEIRDITTDKKLARTFFISPAGNVCFYGECSYYCSTEHALCGKPDQLEGSMAALLPDKALAKRRSWRSPWRRSYHKSKKAEWELDPNYCSQVRRTPPYDSGHRLLDLIDMAVLDFLMGNMDRHHYETFEKFGNDTFLLHLDNGRGFGTHSRDEMSILAPLQQCCSIKKSTYLRLRLLATEPYRLSELLREALAADHLAPILAEPHLQALDRRLGKVLAAVGRCLATAAQPHQVLVDDIGPWL", "length": 701, "header": "tr|A0A8V0YIN9-1|A0A8V0YIN9_CHICK Isoform 1 of FAM20 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=FAM20CL PE=1 SV=1 CANONICAL=A0A8V0YIN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN4/entry", "sequence": { "sequence": "MRLQLQTLVQRKFKVLLLLLLLLALLLHVTMDLALPATRRPCSSDAKEPKASGTSTGSPLLASPEKLSLRILQDFSGSNGSLEKSSQPQGAGPKGKDGDVGIQHRHGDVGPAWAKGSKLAALFEHPLYNIPLPEVKDKDKLFIANPMEKFSLRSSRSDEWQSRNQETPADFFYFSDFERHNAEIAAFHLDRILDFRRIPPVSGRLVNITKEIRDITTDKKLARTFFISPGGSWIPTTAARCAGRRPMTVVIASLTSLTWQCLISSWATWTDTTMRPLRNLGTTPFCFTWTMAAASARTPATRCPSWPLSSSAAASRSPPTCGCGCWPPSPTA", "length": 332, "header": "tr|A0A8V0YIN4-1|A0A8V0YIN9_CHICK Computationally mapped isoform of FAM20 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=FAM20CL PE=1 SV=1 CANONICAL=A0A8V0YIN9-1" }, "locus": { "chromosome": "1", "start_pos": 50846642, "end_pos": 50842675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030455.1", "url": "https://www.ensembl.org/id/ENSGALT00010030455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017667.1", "url": "https://www.ensembl.org/id/ENSGALP00010017667.1" } ] } }, { "isoform_ac": "A0A8V0YIN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9/entry", "sequence": { "sequence": "MEERATAPPRRLLSKTCIQTGSSKAPGARRRVPFPGEAICSPLPGSFCMACSSPALREALLLLATLFARGKGKETRCWLDLGLLEMSAGGGFQATVVPRGHGEPGTPYSCCPRGLDGASMGLVWRAARVRGCRTALPDFCPEERRGSGCTDSLCPVWVPAPRQGRMRLQLQTLVQRKFKVLLLLLLLLALLLHVTMDLALPATRRPCSSDAKEPKASGTSTGSPLLASPEKLSLRILQDFSGSNGSLEKSSQPQGAGPKGKDGDVGIQHRHGDVGPAWAKGSKLAALFEHPLYNIPLPEVKDKDKLFIANPMEKFSLRSSRSDEWVSSSKAEMVLPTGKTAYDTYPAWLKFHIGINRYELYPRRDPLMPTLLQDLATMKIVSSVQKSGGTQLKLIMTFSNYGQALFKPMKQSRNQETPADFFYFSDFERHNAEIAAFHLDRILDFRRIPPVSGRLVNITKEIRDITTDKKLARTFFISPAGNVCFYGECSYYCSTEHALCGKPDQLEGSMAALLPDKALAKRRSWRSPWRRSYHKSKKAEWELDPNYCSQVRRTPPYDSGHRLLDLIDMAVLDFLMGNMDRHHYETFEKFGNDTFLLHLDNGRGFGTHSRDEMSILAPLQQCCSIKKSTYLRLRLLATEPYRLSELLREALAADHLAPILAEPHLQALDRRLGKVLAAVGRCLATAAQPHQVLVDDIGPWL", "length": 701, "header": "tr|A0A8V0YIN9-1|A0A8V0YIN9_CHICK Isoform 1 of FAM20 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=FAM20CL PE=1 SV=1 CANONICAL=A0A8V0YIN9-1" }, "locus": { "chromosome": "1", "start_pos": 50846818, "end_pos": 50840904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030466.1", "url": "https://www.ensembl.org/id/ENSGALT00010030466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017672.1", "url": "https://www.ensembl.org/id/ENSGALP00010017672.1" } ] } }, { "isoform_ac": "A0A8V0YNH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH5/entry", "sequence": { "sequence": "MRLQLQTLVQRKFKVLLLLLLLLALLLHVTMDLALPATRRPCSSDAKEPKASGTSTGSPLLASPEKLSLRILQDFSGSNGSLEKSSQPQGAGPKGKDGDVGIQHRHGDVGPAWAKGSKLAALFEHPLYNIPLPEVKDKDKLFIANPMEKFSLRSSRSDEWQSRNQETPADFFYFSDFERHNAEIAAFHLDRILDFRRIPPVSGRLVNITKEIRDITTDKKLARTFFISPAGNVCFYGECSYYCSTEHALCGKPDQLEGSMAALLPDKALAKRRSWRSPWRRSYHKSKKAEWELDPNYCSQVRRTPPYDSGHRLLDLIDMAVLDFLMGNMDRHHYETFEKFGNDTFLLHLDNGRGFGTHSRDEMSILAPLQQCCSIKKSTYLRLRLLATEPYRLSELLREALAADHLAPILAEPHLQALDRRLGKVLAAVGRCLATAAQPHQVLVDDIGPWL", "length": 451, "header": "tr|A0A8V0YNH5-1|A0A8V0YNH5_CHICK Computationally mapped isoform of FAM20 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=FAM20CL PE=1 SV=1 CANONICAL=A0A8V0YIN9-1" }, "locus": { "chromosome": "1", "start_pos": 50846818, "end_pos": 50842675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030461.1", "url": "https://www.ensembl.org/id/ENSGALT00010030461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017670.1", "url": "https://www.ensembl.org/id/ENSGALP00010017670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "enamel mineralization", "id": "GO:0070166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" }, { "id": "PF06702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 475, "end_pos": 687, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 178, "amino_acid": "Phe", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 178, "end_pos": 178, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 350, "amino_acid": "Lys", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 350, "end_pos": 350, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 428, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 428, "end_pos": 428, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN9" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 600, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 600, "end_pos": 600, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 592, "end_pos": 594 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIN5-1", "uniprot_ac": "A0A8V0YIN5", "uniprot_id": "A0A8V0YIN5_CHICK", "mass": { "chemical_mass": 247524.0, "monoisotopic_mass": 247524.0 }, "refseq": { "ac": "XP_015138425", "name": "receptor-type tyrosine-protein phosphatase beta isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138425" }, "gene_names": [ { "name": "PTPRB", "type": "recommended", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "name": "PTPRB", "type": "synonym", "evidence": [ { "id": "XP_015138425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138425" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5/entry#names_and_taxonomy" } ] }, { "name": "receptor-type tyrosine-protein phosphatase beta isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015138425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138425" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138425" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPRB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5", "locus": { "chromosome": "1", "start_pos": 35969050, "end_pos": 36031456, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013259", "url": "https://www.ensembl.org/id/ENSGALG00010013259" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417853", "url": "https://www.ncbi.nlm.nih.gov/gene/417853", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417853", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417853", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIN5", "url": "https://www.orthodb.org/?gene=A0A8V0YIN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJE9", "url": "https://www.orthodb.org/?gene=A0A8V0YJE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLC2", "url": "https://www.orthodb.org/?gene=A0A8V0YLC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138425", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLIHVLVFTCLALMFSEAFLIIHVQRQQCLSERRGVIMERCNMSSPNQQWQWMADDKLFHMKSGQCLSISTRSALSSRSIIINCSQAVRWTCHEEDGLLKVANSSLFLTKQGQKVMAKQSKKYLHTWMQLEASETGKPVYVNLCSKQDLQDADTFVWSTTTTSSPLNTTTSRPDNLPASSSTQMSIRNVTEHFTKNFIENLYFDLKSAVTEKPTVPTTPPQYSSTTEEAARGEAAGCSANLTERRVAARSAWLRWSAAAHACNFNLTGRSEDGRPAGCRPASAGNGSYGCTVRDLEAGTWYHLRIEPLADGEAANVTLQTDPLPPPRFEINKEKTTFTSLQVRWDPSPGKVDLYNIVVFDHSNKKLQESSIPGRFSKTEETFTGLVPGNKYNIVLTAVAGNKSTPEFRINGSTVPSPVKNIQVIVKTDSIHASWSPGSGHVDLYKLVLFDNHGTVHESHQENPLTSYIFSGLTAGHLYNLSVITQAAELESTAFRIVRTAPAEVLDLTVTNDDSFDTLKVKWRRPSGGVDFYNITLSHLRSVKEVKTLQPAVTETHFDKLTPGRLYQITARTISGELFTDKMATGRTFPQKVSELKAGGGGWLRTLRVNWLPPAGDLERYHLLLWNHSALVLNTTLGKNVTEYLVRDVGLIPGRQYEVEVVVESGDLQSRASCTGRTAPEPVLQLRVKHANESSLSVMWVTPVAEWDSYVVSLGDRDLTVIKKGLGKEAKEFTFNELVPGRKYTATVTTISGILSNWTSVEGRTVPAQVTGLTVASQGSTNSLFTNWTKALGDVDSYQVLLIHENVVIKNETVPSETNEYHFYPLKPGGLYSVVVTTVSGGISSRQTIAEGRTVPSSVTGVTVNNSGRSDYLSVSWLPASGDVDSYLVTLSHDDQIIQTLTISKSLSECSFSSLTPGTLYNVMITTKSGKYENHSFSRERTVPSGVQGLTVSNSARSDYLKVSWLHASGSFDSYEVIIKNNNDFIQTKSVPKDENECVFTNLVPGRQYSVTVSTRSGKYETSERVFGRTMPESVKGLTLSNRSTEDLRVTWSKAEGDVDKYEIQLLYNDMKIFPPIFLGNTIEECWFTALTPGRLYKIVVLTISGDAQRATFIEGLTIPSAVRNINVSPNGMTDSLKVSWTPGGGDVDSYTVTIFQQNHQLDSRSVSKDVSEHTFHDLEAGEQYRVVVQSNSGALHNSLAAFGRTIPASVQELLADHAYSSHSLLVSWQKAPGVAERYDILLLNEQGVLLSNKSEPATAKQHKFEDLLPGKKYKIHILTVSGGLFSKRAETVGRTVPAAVTNLKVTKNTTDQLSFSWTTSQGELDSYDIFLYNPDKSLHDRISGEQHLQQCSFQNLRQGRMYRMVIVTHSGDLTNESSVFGRTAPAPVVGLKASNRNMTDSLWFTWNPAAGDVDFYEFNLYNPNGTQKESLQGKDLKEWYFQGLVPGRKYTLVVVTHSGDLINTANAEGRTAPSPPNTVSFTDVANTSLSITWLGPPDWTDYDDFELQWLPKDPLTVFNPYSSSKSKVRIIYGLRPGRLYKFSVRTVSGDSWKTYSQSQSESVRTRPDKIQSLHCRPQTSTAIACSWTPPDSDFDGYSVECKKLDTREVEFSKRIEKDRTLLNIMTLVPHKRYLVSIKVHSADMTSEVVEDSTITMIDRPPQPPPDIRVNKKEVLITKSSINFTFNCSWFSDTNGAVKYFTVVVREADGSEGPKPDEQHPLPSYLEYKHNDSIRIYQTNYFASRCAENPDSDYKSFDIKLGGEMENLGGKCDPDQQKFCDGPLKPRTAYRISIRAFTQLFSEDPKELPQPLFADTFFSLPITTEAEPLFGVIEGVSAGLFLIVMLVAVTALFVCRQKVSNGHERPTARLSIRRDKPLAVHLNLGQKGNRKTSSPIKVSHFEAHFTKLQADSNYLLSKEYEDLKDVGRNQTCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDEFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPLDQDSLYYGDLIVEMLSESVLPEWTIREFKICSEEQLDSTRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPDTGPTVVHCSAGVGRTGTFIALDRILQQLDSKDTVDIYAAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDAVYSRH", "length": 2211, "header": "tr|A0A8V0YIN5-1|A0A8V0YIN5_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPRB PE=3 SV=1 CANONICAL=A0A8V0YIN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5/entry", "sequence": { "sequence": "MESLIHVLVFTCLALMFSEAFLIIHVQRQQCLSERRGVIMERCNMSSPNQQWQWMADDKLFHMKSGQCLSISTRSALSSRSIIINCSQAVRWTCHEEDGLLKVANSSLFLTKQGQKVMAKQSKKYLHTWMQLEASETGKPVYVNLCSKQDLQDADTFVWSTTTTSSPLNTTTSRPDNLPASSSTQMSIRNVTEHFTKNFIENLYFDLKSAVTEKPTVPTTPPQYSSTTEEAARGEAAGCSANLTERRVAARSAWLRWSAAAHACNFNLTGRSEDGRPAGCRPASAGNGSYGCTVRDLEAGTWYHLRIEPLADGEAANVTLQTDPLPPPRFEINKEKTTFTSLQVRWDPSPGKVDLYNIVVFDHSNKKLQESSIPGRFSKTEETFTGLVPGNKYNIVLTAVAGNKSTPEFRINGSTVPSPVKNIQVIVKTDSIHASWSPGSGHVDLYKLVLFDNHGTVHESHQENPLTSYIFSGLTAGHLYNLSVITQAAELESTAFRIVRTAPAEVLDLTVTNDDSFDTLKVKWRRPSGGVDFYNITLSHLRSVKEVKTLQPAVTETHFDKLTPGRLYQITARTISGELFTDKMATGRTFPQKVSELKAGGGGWLRTLRVNWLPPAGDLERYHLLLWNHSALVLNTTLGKNVTEYLVRDVGLIPGRQYEVEVVVESGDLQSRASCTGRTAPEPVLQLRVKHANESSLSVMWVTPVAEWDSYVVSLGDRDLTVIKKGLGKEAKEFTFNELVPGRKYTATVTTISGILSNWTSVEGRTVPAQVTGLTVASQGSTNSLFTNWTKALGDVDSYQVLLIHENVVIKNETVPSETNEYHFYPLKPGGLYSVVVTTVSGGISSRQTIAEGRTVPSSVTGVTVNNSGRSDYLSVSWLPASGDVDSYLVTLSHDDQIIQTLTISKSLSECSFSSLTPGTLYNVMITTKSGKYENHSFSRERTVPSGVQGLTVSNSARSDYLKVSWLHASGSFDSYEVIIKNNNDFIQTKSVPKDENECVFTNLVPGRQYSVTVSTRSGKYETSERVFGRTMPESVKGLTLSNRSTEDLRVTWSKAEGDVDKYEIQLLYNDMKIFPPIFLGNTIEECWFTALTPGRLYKIVVLTISGDAQRATFIEGLTIPSAVRNINVSPNGMTDSLKVSWTPGGGDVDSYTVTIFQQNHQLDSRSVSKDVSEHTFHDLEAGEQYRVVVQSNSGALHNSLAAFGRTIPASVQELLADHAYSSHSLLVSWQKAPGVAERYDILLLNEQGVLLSNKSEPATAKQHKFEDLLPGKKYKIHILTVSGGLFSKRAETVGRTVPAAVTNLKVTKNTTDQLSFSWTTSQGELDSYDIFLYNPDKSLHDRISGEQHLQQCSFQNLRQGRMYRMVIVTHSGDLTNESSVFGRTAPAPVVGLKASNRNMTDSLWFTWNPAAGDVDFYEFNLYNPNGTQKESLQGKDLKEWYFQGLVPGRKYTLVVVTHSGDLINTANAEGRTAPSPPNTVSFTDVANTSLSITWLGPPDWTDYDDFELQWLPKDPLTVFNPYSSSKSKVRIIYGLRPGRLYKFSVRTVSGDSWKTYSQSQSESVRTRPDKIQSLHCRPQTSTAIACSWTPPDSDFDGYSVECKKLDTREVEFSKRIEKDRTLLNIMTLVPHKRYLVSIKVHSADMTSEVVEDSTITMIDRPPQPPPDIRVNKKEVLITKSSINFTFNCSWFSDTNGAVKYFTVVVREADGSEGPKPDEQHPLPSYLEYKHNDSIRIYQTNYFASRCAENPDSDYKSFDIKLGGEMENLGGKCDPDQQKFCDGPLKPRTAYRISIRAFTQLFSEDPKELPQPLFADTFFSLPITTEAEPLFGVIEGVSAGLFLIVMLVAVTALFVCRQKVSNGHERPTARLSIRRDKPLAVHLNLGQKGNRKTSSPIKVSHFEAHFTKLQADSNYLLSKEYEDLKDVGRNQTCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDEFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPLDQDSLYYGDLIVEMLSESVLPEWTIREFKICSEEQLDSTRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPDTGPTVVHCSAGVGRTGTFIALDRILQQLDSKDTVDIYAAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDAVYSRH", "length": 2211, "header": "tr|A0A8V0YIN5-1|A0A8V0YIN5_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPRB PE=3 SV=1 CANONICAL=A0A8V0YIN5-1" }, "locus": { "chromosome": "1", "start_pos": 36031425, "end_pos": 35970172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031883.1", "url": "https://www.ensembl.org/id/ENSGALT00010031883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018686.1", "url": "https://www.ensembl.org/id/ENSGALP00010018686.1" } ] } }, { "isoform_ac": "A0A8V0YJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE9/entry", "sequence": { "sequence": "MESLIHVLVFTCLALMFSEAFLIIHVQRQQCLSERRGVIMERCNMSSPNQQWQWMADDKLFHMKSGQCLSISTRSALSSRSIIINCSQAVRWTCHEEDGLLKVANSSLFLTKQGQKVMAKQSKKYLHTWMQLEASETGKPVYVNLCSKQDLQDADTFVWSTTTTSSPLNTTTSRPDNLPASSSTQMSIRNVTEHFTKNFIENLYFDLKSAVTEKPTVPTTPPQYSSTTEEEKTTFTSLQVRWDPSPGKVDLYNIVVFDHSNKKLQESSIPGRFSKTEETFTGLVPGNKYNIVLTAVAGNKSTPEFRINGSTVPSPVKNIQVIVKTDSIHASWSPGSGHVDLYKLVLFDNHGTVHESHQENPLTSYIFSGLTAGHLYNLSVITQAAELESTAFRIVRTAPAEVLDLTVTNDDSFDTLKVKWRRPSGGVDFYNITLSHLRSVKEVKTLQPAVTETHFDKLTPGRLYQITARTISGELFTDKMATGRTFPQKVSELKAGGGGWLRTLRVNWLPPAGDLERYHLLLWNHSALVLNTTLGKNVTEYLVRDVGLIPGRQYEVEVVVESGDLQSRASCTGRTAPEPVLQLRVKHANESSLSVMWVTPVAEWDSYVVSLGDRDLTVIKKGLGKEAKEFTFNELVPGRKYTATVTTISGILSNWTSVEGRTVPAQVTGLTVASQGSTNSLFTNWTKALGDVDSYQVLLIHENVVIKNETVPSETNEYHFYPLKPGGLYSVVVTTVSGGISSRQTIAEGRTVPSSVTGVTVNNSGRSDYLSVSWLPASGDVDSYLVTLSHDDQIIQTLTISKSLSECSFSSLTPGTLYNVMITTKSGKYENHSFSRERTVPSGVQGLTVSNSARSDYLKVSWLHASGSFDSYEVIIKNNNDFIQTKSVPKDENECVFTNLVPGRQYSVTVSTRSGKYETSERVFGRTMPESVKGLTLSNRSTEDLRVTWSKAEGDVDKYEIQLLYNDMKIFPPIFLGNTIEECWFTALTPGRLYKIVVLTISGDAQRATFIEGLTIPSAVRNINVSPNGMTDSLKVSWTPGGGDVDSYTVTIFQQNHQLDSRSVSKDVSEHTFHDLEAGEQYRVVVQSNSGALHNSLAAFGRTIPASVQELLADHAYSSHSLLVSWQKAPGVAERYDILLLNEQGVLLSNKSEPATAKQHKFEDLLPGKKYKIHILTVSGGLFSKRAETVGRTVPAAVTNLKVTKNTTDQLSFSWTTSQGELDSYDIFLYNPDKSLHDRISGEQHLQQCSFQNLRQGRMYRMVIVTHSGDLTNESSVFGRTAPAPVVGLKASNRNMTDSLWFTWNPAAGDVDFYEFNLYNPNGTQKESLQGKDLKEWYFQGLVPGRKYTLVVVTHSGDLINTANAEGRTAPSPPNTVSFTDVANTSLSITWLGPPDWTDYDDFELQWLPKDPLTVFNPYSSSKSKVRIIYGLRPGRLYKFSVRTVSGDSWKTYSQSQSESVRTRPDKIQSLHCRPQTSTAIACSWTPPDSDFDGYSVECKKLDTREVEFSKRIEKDRTLLNIMTLVPHKRYLVSIKVHSADMTSEVVEDSTITMIDRPPQPPPDIRVNKKEVLITKSSINFTFNCSWFSDTNGAVKYFTVVVREADGSEGPKPDEQHPLPSYLEYKHNDSIRIYQTNYFASRCAENPDSDYKSFDIKLGGEMENLGGKCDPDQQKFCDGPLKPRTAYRISIRAFTQLFSEDPKELPQPLFADTFFSLPITTEAEPLFGVIEGVSAGLFLIVMLVAVTALFVCRQKVSNGHERPTARLSIRRDKPLAVHLNLGQKGNRKTSSPIKVSHFEAHFTKLQADSNYLLSKEYEDLKDVGRNQTCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDEFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPLDQDSLYYGDLIVEMLSESVLPEWTIREFKICSEEQLDSTRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPDTGPTVVHCSAGVGRTGTFIALDRILQQLDSKDTVDIYAAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDAVYSRH", "length": 2107, "header": "tr|A0A8V0YJE9-1|A0A8V0YJE9_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPRB PE=3 SV=1 CANONICAL=A0A8V0YIN5-1" }, "locus": { "chromosome": "1", "start_pos": 36031425, "end_pos": 35970172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031887.1", "url": "https://www.ensembl.org/id/ENSGALT00010031887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018689.1", "url": "https://www.ensembl.org/id/ENSGALP00010018689.1" } ] } }, { "isoform_ac": "A0A8V0YLC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC2/entry", "sequence": { "sequence": "MLSYGAGLALCTVLALSEAARGEAAGCSANLTERRVAARSAWLRWSAAAHACNFNLTGRSEDGRPAGCRPASAGNGSYGCTVRDLEAGTWYHLRIEPLADGEAANVTLQTDPLPPPRFEINKEKTTFTSLQVRWDPSPGKVDLYNIVVFDHSNKKLQESSIPGRFSKTEETFTGLVPGNKYNIVLTAVAGNKSTPEFRINGSTVPSPVKNIQVIVKTDSIHASWSPGSGHVDLYKLVLFDNHGTVHESHQENPLTSYIFSGLTAGHLYNLSVITQAAELESTAFRIVRTAPAEVLDLTVTNDDSFDTLKVKWRRPSGGVDFYNITLSHLRSVKEVKTLQPAVTETHFDKLTPGRLYQITARTISGELFTDKMATGRTFPQKVSELKAGGGGWLRTLRVNWLPPAGDLERYHLLLWNHSALVLNTTLGKNVTEYLVRDVGLIPGRQYEVEVVVESGDLQSRASCTGRTAPEPVLQLRVKHANESSLSVMWVTPVAEWDSYVVSLGDRDLTVIKKGLGKEAKEFTFNELVPGRKYTATVTTISGILSNWTSVEGRTVPAQVTGLTVASQGSTNSLFTNWTKALGDVDSYQVLLIHENVVIKNETVPSETNEYHFYPLKPGGLYSVVVTTVSGGISSRQTIAEGRTVPSSVTGVTVNNSGRSDYLSVSWLPASGDVDSYLVTLSHDDQIIQTLTISKSLSECSFSSLTPGTLYNVMITTKSGKYENHSFSRERTVPSGVQGLTVSNSARSDYLKVSWLHASGSFDSYEVIIKNNNDFIQTKSVPKDENECVFTNLVPGRQYSVTVSTRSGKYETSERVFGRTMPESVKGLTLSNRSTEDLRVTWSKAEGDVDKYEIQLLYNDMKIFPPIFLGNTIEECWFTALTPGRLYKIVVLTISGDAQRATFIEGLTIPSAVRNINVSPNGMTDSLKVSWTPGGGDVDSYTVTIFQQNHQLDSRSVSKDVSEHTFHDLEAGEQYRVVVQSNSGALHNSLAAFGRTIPASVQELLADHAYSSHSLLVSWQKAPGVAERYDILLLNEQGVLLSNKSEPATAKQHKFEDLLPGKKYKIHILTVSGGLFSKRAETVGRTVPAAVTNLKVTKNTTDQLSFSWTTSQGELDSYDIFLYNPDKSLHDRISGEQHLQQCSFQNLRQGRMYRMVIVTHSGDLTNESSVFGRTAPAPVVGLKASNRNMTDSLWFTWNPAAGDVDFYEFNLYNPNGTQKESLQGKDLKEWYFQGLVPGRKYTLVVVTHSGDLINTANAEGRTAPSPPNTVSFTDVANTSLSITWLGPPDWTDYDDFELQWLPKDPLTVFNPYSSSKSKVRIIYGLRPGRLYKFSVRTVSGDSWKTYSQSQSESVRTRPDKIQSLHCRPQTSTAIACSWTPPDSDFDGYSVECKKLDTREVEFSKRIEKDRTLLNIMTLVPHKRYLVSIKVHSADMTSEVVEDSTITMIDRPPQPPPDIRVNKKEVLITKSSINFTFNCSWFSDTNGAVKYFTVVVREADGSEGPKPDEQHPLPSYLEYKHNDSIRIYQTNYFASRCAENPDSDYKSFDIKLGGEMENLGGKCDPDQQKFCDGPLKPRTAYRISIRAFTQLFSEDPKELPQPLFADTFFSLPITTEAEPLFGVIEGVSAGLFLIVMLVAVTALFVCRQKVSNGHERPTARLSIRRDKPLAVHLNLGQKGNRKTSSPIKVSHFEAHFTKLQADSNYLLSKEYEDLKDVGRNQTCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDEFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPLDQDSLYYGDLIVEMLSESVLPEWTIREFKICSEEQLDSTRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPDTGPTVVHCSAGVGRTGTFIALDRILQQLDSKDTVDIYAAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDAVYSRH", 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"go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase inhibitor activity", "id": "GO:0030293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1254, "end_pos": 1256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1310, "end_pos": 1312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1377, "end_pos": 1379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1399, "end_pos": 1401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1488, "end_pos": 1490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1684, "end_pos": 1686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1688, "end_pos": 1690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1732, "end_pos": 1734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1930, "end_pos": 1932, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1973, "end_pos": 1975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2106, "end_pos": 2108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-GGA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, tertiary granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "P15120-1", "Q5F352-1", "A0A8V0ZZE4-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6798747", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798747" } ] }, { "id": "R-GGA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "A0A3Q2U2N5-1", "A0A8V1AKE3-1", "P15120-1", "A0A1D5P3W4-1", "Q5F3C1-1", "A0A8V1AN75-1", "A0A8V0ZZE4-1", "F1NSA8-1", "A0A8V0YXK7-1", "A0A8V0Y5N7-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799350" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2U2N5", "gene_name": "ATP8A1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y5N7", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YJI3", "gene_name": "ATP11A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] } ] }, { "uniprot_ac": "A0A8V0YMC7", "gene_name": "PLD1", "activity": [ { "ec_number": "3.1.4.4", "activity": "a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ] }, { "ec_number": "3.1.4.4", "activity": "", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0YXK7", "gene_name": "HMOX2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0A8V0YXK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXK7" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "A0A8V0YXK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXK7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "A0A8V1AKE3", "gene_name": "AGPAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0A8V1AKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE3" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0A8V1AKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE3" } ] } ] }, { "uniprot_ac": "A0A8V1AN75", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": 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"length": 1037, "header": "tr|A0A8V0YIQ4-1|A0A8V0YIQ4_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YIQ4-1" }, "locus": { "chromosome": "W", "start_pos": 6425937, "end_pos": 6417659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030500.1", "url": "https://www.ensembl.org/id/ENSGALT00010030500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017687.1", "url": "https://www.ensembl.org/id/ENSGALP00010017687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 773, "end_pos": 939, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" }, { "id": "PS50175", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 70, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 706, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ4" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 323, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIR7-1", "uniprot_ac": "A0A8V0YIR7", "uniprot_id": "A0A8V0YIR7_CHICK", "mass": { "chemical_mass": 27305.0, "monoisotopic_mass": 27305.0 }, "refseq": { "ac": "XP_015153269", "name": "yrdC domain-containing protein, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153269" }, "gene_names": [ { "name": "YRDC", "type": "recommended", "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ] }, { "name": "YRDC", "type": "synonym", "evidence": [ { "id": "XP_015153269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153269" } ] } ], "protein_names": [ { "name": "Threonylcarbamoyl-AMP synthase", "type": "recommended", "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.87", "type": "synonym", "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7/entry#names_and_taxonomy" } ] }, { "name": "yrdC domain-containing protein, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015153269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153269" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153269.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153269" } ] }, { "annotation": "Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7#function" }, { "database": "UniProtKB", "id": "ARBA00058524", "url": "https://www.uniprot.org/uniprotkb/ARBA00058524#function" }, { "database": "UniProtKB", "id": "A0A8V0YLG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YRDC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7", "locus": { "chromosome": "23", "start_pos": 3931880, "end_pos": 3929185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013277", "url": "https://www.ensembl.org/id/ENSGALG00010013277" } ] } } ], "crossref": [ { "id": "A0A8V0YIR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "419610", "url": "https://www.ncbi.nlm.nih.gov/gene/419610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419610", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDLCAVW", "url": "https://omabrowser.org/oma/group/RDLCAVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR7", "url": "https://www.orthodb.org/?gene=A0A8V0YIR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLG4", "url": "https://www.orthodb.org/?gene=A0A8V0YLG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17490:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17490:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6787450", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787450", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015153269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36407", "url": "https://www.rhea-db.org/rhea/36407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGRPGLGEMGGGRPPGREALSAETADQSPTRVRLRLRTEPAVSAGWREAVAAAVGALQEGGLVAVPTDTVYGVACLAQDSRAVQSIYSLKGRNGTKPLAICLGDVEHIYRYCHVNVPDELLQDLLPGPVTLVLKRSEELNKDLNPFTSLVGVRIPNHPFIRELARACPGPLALTSANISSQASTLTVSEFQDLWPQLSLVVDGGPIGDVQSPECRLGSTVVDLSVSGKFTIIRPGCALTSTVEILRQKYGLVPESS", "length": 258, "header": "tr|A0A8V0YIR7-1|A0A8V0YIR7_CHICK Isoform 1 of Threonylcarbamoyl-AMP synthase OS=Gallus gallus OX=9031 GN=YRDC PE=3 SV=1 CANONICAL=A0A8V0YIR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7/entry", "sequence": { "sequence": "MSGGRPGLGEMGGGRPPGREALSAETADQSPTRVRLRLRTEPAVSAGWREAVAAAVGALQEGGLVAVPTDTVYGVACLAQDSRAVQSIYSLKGRNGTKPLAICLGDVEHIYRYCHVNVPDELLQDLLPGPVTLVLKRSEELNKDLNPFTSLVGVRIPNHPFIRELARACPGPLALTSANISSQASTLTVSEFQDLWPQLSLVVDGGPIGDVQSPECRLGSTVVDLSVSGKFTIIRPGCALTSTVEILRQKYGLVPESS", "length": 258, "header": "tr|A0A8V0YIR7-1|A0A8V0YIR7_CHICK Isoform 1 of Threonylcarbamoyl-AMP synthase OS=Gallus gallus OX=9031 GN=YRDC PE=3 SV=1 CANONICAL=A0A8V0YIR7-1" }, "locus": { "chromosome": "23", "start_pos": 3931591, "end_pos": 3929348, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031919.1", "url": "https://www.ensembl.org/id/ENSGALT00010031919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018716.1", "url": "https://www.ensembl.org/id/ENSGALP00010018716.1" } ] } }, { "isoform_ac": "A0A8V0YLG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG4/entry", "sequence": { "sequence": "MLRVQRAALAGLVRVAEGLPGPGHARSSCLLPLPGSAARPEPRGWREAVAAAVGALQEGGLVAVPTDTVYGVACLAQDSRAVQSIYSLKGRNGTKPLAICLGDVEHIYRYCHVNVPDELLQDLLPGPVTLVLKRSEELNKDLNPFTSLVGVRIPNHPFIRELARACPGPLALTSANISSQASTLTVSEFQDLWPQLSLVVDGGPIGDVQSPECRLGSTVVDLSVSGKFTIIRPGCALTSTVEILRQKYGLVPESS", "length": 255, "header": "tr|A0A8V0YLG4-1|A0A8V0YLG4_CHICK Computationally mapped isoform of Threonylcarbamoyl-AMP synthase OS=Gallus gallus OX=9031 GN=YRDC PE=3 SV=1 CANONICAL=A0A8V0YIR7-1" }, "locus": { "chromosome": "23", "start_pos": 3931591, "end_pos": 3929190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031924.1", "url": "https://www.ensembl.org/id/ENSGALT00010031924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018721.1", "url": "https://www.ensembl.org/id/ENSGALP00010018721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419610", "resource": "KEGG Pathway" }, { "id": "R-GGA-6787450", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6787450", "resource": "Reactome", "description": "tRNA modification in the mitochondrion" } ], "orthologs": [ { "uniprot_canonical_ac": "F4K0E6-1", "protein_name": "Threonylcarbamoyl-AMP synthase", "gene_name": "MUP24.1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNLSTRLAEKLPGILPAPSSPLLRKGVSELRCFSIANQSRRLRWGLQKKMVWSLERAETCVVSKSCLVHPATEAYAQEAIEAIKSEKVIAVPTDTLYGFACDACSLEAVSRIYEIKGRKLTSPLAICVGDVLDIKRVATTSHLPHGLLDSLLPGPVTLVLQRGESSILEKSLNPGIGTIGVRVPDCEFIREVSRGSGSVLALTSANLSGDRSSVCVKDFENLWQHCAYVYDGGLLPSGRAGSTIVDLTKVGKYKIIRPGSAKQATVAILEKYLLEEEEEEDHKEKRAS", "length": 288 }, "evidence": [ { "id": "A0A8V0YIR7", "url": "https://omabrowser.org/oma/group/A0A8V0YIR7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3U5F4-1", "protein_name": "Threonylcarbamoyl-AMP synthase", "gene_name": "Yrdc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTARPCAGLRAAVAAGMGLSDGPASSGRGCRLLRPPEPAPALPGARLLRLPESEPVEAASPERSGWTEALRAAVAELRAGAVVAVPTDTLYGLACSASSSAALSCVYRLKGRSEAKPLAVCLGRVADVYRYCQVRVPRELLEDLFPGPVTLVMERSEELNKDLNPFTRLVGIRIPDHAFMLDLAQMFGGPLALTSANLSSQASSLSVEEFQDLWPHLSLVIDGGPIGDSQSPECRLGSTVVDLSVPGKFGIIRPGCALENTTSILQQKYGLLPSQGSCS", "length": 280 }, "evidence": [ { "id": "A0A8V0YIR7", "url": "https://omabrowser.org/oma/group/A0A8V0YIR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86U90-1", "protein_name": "Threonylcarbamoyl-AMP synthase", "gene_name": "YRDC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPARRCRGMRAAVAASVGLSEGPAGSRSGRLFRPPSPAPAAPGARLLRLPGSGAVQAASPERAGWTEALRAAVAELRAGAVVAVPTDTLYGLACAASCSAALRAVYRLKGRSEAKPLAVCLGRVADVYRYCRVRVPEGLLKDLLPGPVTLVMERSEELNKDLNPFTPLVGIRIPDHAFMQDLAQMFEGPLALTSANLSSQASSLNVEEFQDLWPQLSLVIDGGQIGDGQSPECRLGSTVVDLSVPGKFGIIRPGCALESTTAILQQKYGLLPSHASYL", "length": 279 }, "evidence": [ { "id": "A0A8V0YIR7", "url": "https://omabrowser.org/oma/group/A0A8V0YIR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "L-threonylcarbamoyladenylate synthase", "id": "GO:0061710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061710", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36407", "name": "", "equation": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIR7-1", "A0A8V0YBX9-1", "A0A8V0YD24-1" ], "evidence": [ { "id": "36407", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36407" } ] }, { "id": "R-GGA-9611218", "name": "YRDC synthesizes threonylcarbamoyladenylate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-379706" ], "output_participant_list": [ "R-ALL-9611204" ], "enzyme_list": [ "A0A8V0YIR7-1" ], "evidence": [ { "id": "R-GGA-9611218", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9611218" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-379706", "participant_name": "L-Thr [mitochondrial matrix]", "crossref": [ { "id": "57926", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895103", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9611204", "participant_name": "L-threonylcarbamoyladenylate [mitochondrial matrix]", "crossref": [ { "id": "ZINC000096095105", "database": "ZINC", "url": "" }, { "id": "73687", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YBX9", "gene_name": "LOC428714", "activity": [ { "ec_number": "2.7.7.87", "activity": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.", "evidence": [ { "id": "A0A8V0YBX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX9" } ] }, { "ec_number": "2.7.7.87", "activity": "", "evidence": [ { "id": "A0A8V0YBX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX9" } ] } ] }, { "uniprot_ac": "A0A8V0YD24", "gene_name": "LOC112532301", "activity": [ { "ec_number": "2.7.7.87", "activity": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.", "evidence": [ { "id": "A0A8V0YD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ] }, { "ec_number": "2.7.7.87", "activity": "", "evidence": [ { "id": "A0A8V0YD24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD24" } ] } ] }, { "uniprot_ac": "A0A8V0YIR7", "gene_name": "YRDC", "activity": [ { "ec_number": "2.7.7.87", "activity": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.", "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ] }, { "ec_number": "2.7.7.87", "activity": "", "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR7" }, { "id": "PS51163", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51163" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YrdC-like", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 239, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.87", "ec_name": "L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.", "evidence": [ { "id": "2.7.7.87", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.87" }, { "id": "2.7.7.87", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.87" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIT8-1", "uniprot_ac": "A0A8V0YIT8", "uniprot_id": "A0A8V0YIT8_CHICK", "mass": { "chemical_mass": 55560.0, "monoisotopic_mass": 55560.0 }, "refseq": { "ac": "XP_015144570", "name": "NGFI-A-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144570" }, "gene_names": [ { "name": "NAB1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ] }, { "name": "NAB1", "type": "synonym", "evidence": [ { "id": "XP_015144570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144570" } ] } ], "protein_names": [ { "name": "NGFI-A binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8/entry#names_and_taxonomy" } ] }, { "name": "NGFI-A-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015144570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144570.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144570" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8", "locus": { "chromosome": "7", "start_pos": 144883, "end_pos": 168663, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012758", "url": "https://www.ensembl.org/id/ENSGALG00010012758" } ] } } ], "crossref": [ { "id": "A0A8V0YIT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "374126", "url": "https://www.ncbi.nlm.nih.gov/gene/374126", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LCMRDTA", "url": "https://omabrowser.org/oma/group/LCMRDTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIT8", "url": "https://www.orthodb.org/?gene=A0A8V0YIT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12623:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12623:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALPRTLGELQLYRILQKANLLFYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPAWLGISCSSYERSSTTREPHLKMPKCAATTCVQSVAASKSDVVGSLALQGSSEPRLWQGQHTTESEQSLSPADLGSPASPKESSETLDAAAALSVAECVERMVPSLPKSDFNEVKEVLKTNKKLAKMIGHIFEMSDEDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQISREVTYKYTYRTTKSKCGERDELSPKRVKIEDGYPDFQDAVQTLYQPDKMPLALAKGKSEDSAALNAQSEKVMAKQMEFLCNQAGLERRLSTGCYRQNSEEHSPNGMSLDNVDGQGERPLNLRMSNLPNRQLQHISLDGEQHIGKPLCSELIRLYPGGEAKSQSSEGLGILKDFPHSAFNNIERKVIKTEPEDTR", "length": 499, "header": "tr|A0A8V0YIT8-1|A0A8V0YIT8_CHICK Isoform 1 of NGFI-A binding protein 1 OS=Gallus gallus OX=9031 GN=NAB1 PE=1 SV=1 CANONICAL=A0A8V0YIT8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8/entry", "sequence": { "sequence": "MASALPRTLGELQLYRILQKANLLFYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPAWLGISCSSYERSSTTREPHLKMPKCAATTCVQSVAASKSDVVGSLALQGSSEPRLWQGQHTTESEQSLSPADLGSPASPKESSETLDAAAALSVAECVERMVPSLPKSDFNEVKEVLKTNKKLAKMIGHIFEMSDEDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQISREVTYKYTYRTTKSKCGERDELSPKRVKIEDGYPDFQDAVQTLYQPDKMPLALAKGKSEDSAALNAQSEKVMAKQMEFLCNQAGLERRLSTGCYRQNSEEHSPNGMSLDNVDGQGERPLNLRMSNLPNRQLQHISLDGEQHIGKPLCSELIRLYPGGEAKSQSSEGLGILKDFPHSAFNNIERKVIKTEPEDTR", "length": 499, "header": "tr|A0A8V0YIT8-1|A0A8V0YIT8_CHICK Isoform 1 of NGFI-A binding protein 1 OS=Gallus gallus OX=9031 GN=NAB1 PE=1 SV=1 CANONICAL=A0A8V0YIT8-1" }, "locus": { "chromosome": "7", "start_pos": 165060, "end_pos": 147308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030550.1", "url": "https://www.ensembl.org/id/ENSGALT00010030550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017722.1", "url": "https://www.ensembl.org/id/ENSGALP00010017722.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NIJ0-1", "protein_name": "NGFI-A-binding protein 1b", "gene_name": "nab1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATLPRTLGELQLYRILQRANLLCYYDAFIQQGGDDVQQLCEAGEDEFLEIMALVGMASKPLHVRRLQKALRDWVTNPALFNQPLTSLPVCSIPVYKLPEGSPTLLPGNGARGDTQVKVPKCLAASCVDPGKGEPGNGNSSATVSPLQSGSEPRFWANHGTESEHSLSPAELGSPSSPRDGLEALDAAAVQSVAECVERITQTLPKSDPTEVKDQLKGNKKLAKMISHIFDMSEEDPHREEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCMKEVALLTRRDELFGLARQVSREVTYKYTYRTSKSRCGDRDEPSPKRIKTEEGCFDLQEALQAIHMRQETLKEQLAHARSKGEETLGRNIQVQLERLLAKQMEILHDAAAQDRLQALEWRVPPGPYKHSADRQNSNGLTADKNTEPQGERPLNLRVTNQRTSISDGDTPLGKQLANELKRHHHANAENKMSAATENGGDASSRALNLSEKKTIKSEPEDSR", "length": 500 }, "evidence": [ { "id": "A0A8V0YIT8", "url": "https://omabrowser.org/oma/group/A0A8V0YIT8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q13506-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "NAB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCSSYERSSNAREPHLKIPKCAATTCVQSLGQGKSDVVGSLALQSVGESRLWQGHHATESEHSLSPADLGSPASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMNDDDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQISREVTYKYTYRTTKSKCGERDELSPKRIKVEDGFPDFQDSVQTLFQQARAKSEELAALSSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQGERPLNLRMPNLQNRQPHHFVVDGELSRLYPSEAKSHSSESLGILKDYPHSAFTLEKKVIKTEPEDSR", "length": 487 }, "evidence": [ { "id": "A0A8V0YIT8", "url": "https://omabrowser.org/oma/group/A0A8V0YIT8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61122-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "Nab1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCNSYERSSSSREPHLKIPKCAATTCVQSLGQGKSEVGSLALQSVSDSRLWQGHHATESEHSLSPADLGSPASPKESSEALDAAAALSVAECVERMAPTLPKSDLSEVKELLKNNKKLAKMIGHIFEMSDEDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQVSREVTYKYTYRTTRLKCGERDELSPKRIKIEDGFPDFQESVPTLFQQARAKSEELAGLGSQQAEKGMAKQMELLCAQAGYERLQQERRLTAGLYRQSSGEQSPDGGLPSDSSDGQGERPLNLRIPSVQNRQPHHFVVDGELSRLYSSEAKSHSSESLGILKDYPHSAFTLEKKVIKTEPEDSR", "length": 486 }, "evidence": [ { "id": "A0A8V0YIT8", "url": "https://omabrowser.org/oma/group/A0A8V0YIT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62722-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "Nab1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCNSYERSSSAREPHLKVPKCAATTCVQSLGQGKSEVGSLALQSVSESRLWQGHHTTESEHSLSPADLGSPASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKNNKKLAKMIGHIFEMSDEDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQVSREVTYKYTYRTTRLKCGERDELSPKRIKMEDGFPDFQESVPTLFQQARAKSEELAGLSSQAEKGMAKQMELLCAQAGYERLQQERRLMAGLYRQSSGEQSPDGGLPSDGSDGQGERPLNLRIPSVQNRQPHHFVVDGELSRLYSNEVKSHSSESLGILKDYPHSAFTLEKKVIKTEPEDSR", "length": 485 }, "evidence": [ { "id": "A0A8V0YIT8", "url": "https://omabrowser.org/oma/group/A0A8V0YIT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" }, { "id": "PF04905", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAB co-repressor", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 317, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" }, { "id": "PF04904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nab N-terminal", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 83, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT8" }, { "id": "PF04902", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04902" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nab1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 498, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIW8-1", "uniprot_ac": "A0A8V0YIW8", "uniprot_id": "A0A8V0YIW8_CHICK", "mass": { "chemical_mass": 46455.0, "monoisotopic_mass": 46455.0 }, "refseq": { "ac": "NP_001038158", "name": "XK-related protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038158" }, "gene_names": [ { "name": "XKR8", "type": "recommended", "evidence": [ { "id": "A0A8V0YIW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ] }, { "name": "XKR8", "type": "synonym", "evidence": [ { "id": "NP_001038158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038158" } ] }, { "name": "XRG8", "type": "synonym", "evidence": [ { "id": "NP_001038158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038158" } ] } ], "protein_names": [ { "name": 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The reference sequence was derived from JAENSK010000339.1. On Sep 23, 2021 this sequence version replaced NP_001038158.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038158" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8", "locus": { "chromosome": "23", "start_pos": 1844356, "end_pos": 1842220, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012773", "url": "https://www.ensembl.org/id/ENSGALG00010012773" } ] } } ], "crossref": [ { "id": "A0A8V0YIW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "724081", "url": "https://www.ncbi.nlm.nih.gov/gene/724081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:724081", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:724081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THIAWLP", "url": "https://omabrowser.org/oma/group/THIAWLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIW8", "url": "https://www.orthodb.org/?gene=A0A8V0YIW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001038158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "38663", "url": "https://www.rhea-db.org/rhea/38663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGPARFGPWQWLLAAAGAAAAVWDAGADVWVAVGYARAGQPGCAALGLGLWAAGSAARQACSWLWFRSDPSTLRPELSRRPLAALHLLQLGFLYRCLRALRLGWRLCREEATEEERDHMAFLTHDISMLRLFETFLENAPQLAVLLYSVLRTNKAEPSQGMGICTAFLCVTWSLLDYHQSLRSFLQDKYEMGWGSSVIYFLWNLFLLCPRILALALFALLWPYGVAVHFPLVWLAMFIWVSLQGTDFMESPGPEQLYRAMVAVILYFSWFNVAPGRTLYRSIIYHSFILLDSTLLTLAWLWGHPPEEQRPYLIPVLCAALPCYLLGLLLRVTYYGWLHPNVRAQPRSGGDEVDAEGRHDGVVEFRSISEPSELRSVSGPDLVNSRLRCLARSHFPLSALAEPRLLNGAAAV", "length": 414, "header": "tr|A0A8V0YIW8-1|A0A8V0YIW8_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XKR8 PE=3 SV=1 CANONICAL=A0A8V0YIW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8/entry", "sequence": { "sequence": "MAARGPARFGPWQWLLAAAGAAAAVWDAGADVWVAVGYARAGQPGCAALGLGLWAAGSAARQACSWLWFRSDPSTLRPELSRRPLAALHLLQLGFLYRCLRALRLGWRLCREEATEEERDHMAFLTHDISMLRLFETFLENAPQLAVLLYSVLRTNKAEPSQGMGICTAFLCVTWSLLDYHQSLRSFLQDKYEMGWGSSVIYFLWNLFLLCPRILALALFALLWPYGVAVHFPLVWLAMFIWVSLQGTDFMESPGPEQLYRAMVAVILYFSWFNVAPGRTLYRSIIYHSFILLDSTLLTLAWLWGHPPEEQRPYLIPVLCAALPCYLLGLLLRVTYYGWLHPNVRAQPRSGGDEVDAEGRHDGVVEFRSISEPSELRSVSGPDLVNSRLRCLARSHFPLSALAEPRLLNGAAAV", "length": 414, "header": "tr|A0A8V0YIW8-1|A0A8V0YIW8_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XKR8 PE=3 SV=1 CANONICAL=A0A8V0YIW8-1" }, "locus": { "chromosome": "23", "start_pos": 1844141, "end_pos": 1842362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030600.1", "url": "https://www.ensembl.org/id/ENSGALT00010030600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017753.1", "url": "https://www.ensembl.org/id/ENSGALP00010017753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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"Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" }, { "name": "neutrophil clearance", "id": "GO:0097350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097350", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" }, { "name": "synapse pruning", "id": "GO:0098883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098883", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" }, { "name": "apoptotic process involved in development", "id": "GO:1902742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38663", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38663" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNWLRCALSIGALQPALPNPAMLPYNWPLLIIDLKDCFFTITLHPQDTKRFAFTLPALNRELPDQRFEWTVLPQRMKNSPTRCQLYVDHALQPLWRKWKQMVIYHCMDDILFAQPEVFTQERIWQIEKTLNREGLMIAPEKVQLSAPWKYLGWTLTNTIVTPQKLQLNIKIETLHDAQRLLGDLKGLRPVVGIPNKLLESLQPLLRGTDLAQPVTVTSQHKRLLQQIMDCIIHGSVRRRDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQQSKTLLQKTELLAEVIKKGRERTLQITGMEPVCVQLPMQKDTLTWYMQHSPQLQDALLGAGSTVSMEKIPNALLHWIGQWSWLWIPKQHETPLQNAIMAYTDTGWKSRTAAVTWQQGGSWRHHLIAADDKDLLQTLELVAIVWAMMNLIDPLNVVTNSLYVAGVCHQIEEAYIKEVQNRRLYELFVQLQRAIRIREHSYAVIHVRGRKWEIDLGEGNARANCLVSLAQRPLVSQHVLA", "length": 520, "header": "tr|A0A8V0YIX1-1|A0A8V0YIX1_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YIX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1/entry", "sequence": { "sequence": "MLNWLRCALSIGALQPALPNPAMLPYNWPLLIIDLKDCFFTITLHPQDTKRFAFTLPALNRELPDQRFEWTVLPQRMKNSPTRCQLYVDHALQPLWRKWKQMVIYHCMDDILFAQPEVFTQERIWQIEKTLNREGLMIAPEKVQLSAPWKYLGWTLTNTIVTPQKLQLNIKIETLHDAQRLLGDLKGLRPVVGIPNKLLESLQPLLRGTDLAQPVTVTSQHKRLLQQIMDCIIHGSVRRRDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQQSKTLLQKTELLAEVIKKGRERTLQITGMEPVCVQLPMQKDTLTWYMQHSPQLQDALLGAGSTVSMEKIPNALLHWIGQWSWLWIPKQHETPLQNAIMAYTDTGWKSRTAAVTWQQGGSWRHHLIAADDKDLLQTLELVAIVWAMMNLIDPLNVVTNSLYVAGVCHQIEEAYIKEVQNRRLYELFVQLQRAIRIREHSYAVIHVRGRKWEIDLGEGNARANCLVSLAQRPLVSQHVLA", "length": 520, "header": "tr|A0A8V0YIX1-1|A0A8V0YIX1_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YIX1-1" }, "locus": { "chromosome": "W", "start_pos": 7990082, "end_pos": 7989485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031640.1", "url": "https://www.ensembl.org/id/ENSGALT00010031640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018504.1", "url": "https://www.ensembl.org/id/ENSGALP00010018504.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 375, "end_pos": 511, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YIX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX1" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 156, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YIX8-1", "uniprot_ac": "A0A8V0YIX8", "uniprot_id": "A0A8V0YIX8_CHICK", "mass": { "chemical_mass": 49727.0, "monoisotopic_mass": 49727.0 }, "refseq": { "ac": "NP_001132950", "name": "monocyte differentiation antigen CD14 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" }, "gene_names": [ { "name": "CD14", "type": "recommended", "evidence": [ { "id": "A0A8V0YIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8" } ] }, { "name": "CD14", "type": "synonym", "evidence": [ { "id": "NP_001132950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" } ] }, { "name": "chCD14", "type": "synonym", "evidence": [ { "id": "NP_001132950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" } ] } ], "protein_names": [ { "name": "Monocyte differentiation antigen CD14", "type": "recommended", "evidence": [ { "id": "A0A8V0YIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8/entry#names_and_taxonomy" } ] }, { "name": "CD14 antigen", "type": "synonym", "evidence": [ { "id": "NP_001132950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" } ] }, { "name": "Myeloid cell-specific leucine-rich glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0YIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8/entry#names_and_taxonomy" } ] }, { "name": "monocyte differentiation antigen CD14 precursor", "type": "synonym", "evidence": [ { "id": "NP_001132950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.71781.1, SRR13267656.3675.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000254.1. On or before Dec 9, 2021 this sequence version replaced XP_015148994.2, NP_001132950.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001132950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" } ] }, { "annotation": "ChCD14 mRNA was expressed in most lymphoid and non-lymphoid tissues, except muscle. ChCD14 mRNA was also expressed in most cells examined but strongly expressed in chicken peripheral blood monocyte/macrophages and KUL01+ splenocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_001132950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950" }, { "database": "PubMed", "id": "18761368", "url": "https://glygen.org/publication/PubMed/18761368" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8", "locus": { "chromosome": "13", "start_pos": 841589, "end_pos": 846117, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011659", "url": "https://www.ensembl.org/id/ENSGALG00010011659" } ] } } ], "crossref": [ { "id": "A0A8V0YIX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100194427", "url": "https://www.ncbi.nlm.nih.gov/gene/100194427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100194427", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100194427", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSSCQWP", "url": "https://omabrowser.org/oma/group/SSSCQWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIX8", "url": "https://www.orthodb.org/?gene=A0A8V0YIX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10630:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10630:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-140534", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-140534", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-166016", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166016", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-166020", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-166166", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2562578", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2562578", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5686938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-936964", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936964", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-937041", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-937041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-937072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-937072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9824878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9824878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001132950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001132950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGAALLLLALGLQQAEGRCVFNRTQEYCLCYRLTQESAGSVIQCLAASAVEFQGGDLEKYADFPIEDLDDSTIDMLGSLQIRKIIFSDLLVPEVLLARVLRFFSYTQVQEMVFKSCSFVGRSSWADMAGRALPIVSLRFHNVTAAALAGREQDLSPLSRWLGALQELSVTASRLAVLPCAVGQALRALRSLDLARNSLGDDSLAPAFCQGAFTQLRVLSLRHNNLTSYSGVCGSVRLLGELQHLDLSHNALTAGTPSSPCQWPATLRIFNLSSAGLDHVLAPLPPALEVLDLSSNRLHAVDISLRSLQALFLSRNALPAAPSIRGCPALHTLHLDNNLIAELPRDEALLLEHLQDVAVAGNPFNCTCGGAGAVQALAAVGCLRQGWPQGYVCHAPARYQGVLLRDVPTSVLQCNPAAVLAPVCTGLALLCVAVAGGLLWARGARPRWLCGLGQREDACSGAEHL", "length": 465, "header": "tr|A0A8V0YIX8-1|A0A8V0YIX8_CHICK Isoform 1 of Monocyte differentiation antigen CD14 OS=Gallus gallus OX=9031 GN=CD14 PE=1 SV=1 CANONICAL=A0A8V0YIX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIX8/entry", "sequence": { "sequence": "MRGAALLLLALGLQQAEGRCVFNRTQEYCLCYRLTQESAGSVIQCLAASAVEFQGGDLEKYADFPIEDLDDSTIDMLGSLQIRKIIFSDLLVPEVLLARVLRFFSYTQVQEMVFKSCSFVGRSSWADMAGRALPIVSLRFHNVTAAALAGREQDLSPLSRWLGALQELSVTASRLAVLPCAVGQALRALRSLDLARNSLGDDSLAPAFCQGAFTQLRVLSLRHNNLTSYSGVCGSVRLLGELQHLDLSHNALTAGTPSSPCQWPATLRIFNLSSAGLDHVLAPLPPALEVLDLSSNRLHAVDISLRSLQALFLSRNALPAAPSIRGCPALHTLHLDNNLIAELPRDEALLLEHLQDVAVAGNPFNCTCGGAGAVQALAAVGCLRQGWPQGYVCHAPARYQGVLLRDVPTSVLQCNPAAVLAPVCTGLALLCVAVAGGLLWARGARPRWLCGLGQREDACSGAEHL", "length": 465, "header": "tr|A0A8V0YIX8-1|A0A8V0YIX8_CHICK Isoform 1 of Monocyte differentiation antigen CD14 OS=Gallus gallus OX=9031 GN=CD14 PE=1 SV=1 CANONICAL=A0A8V0YIX8-1" }, "locus": { "chromosome": "13", "start_pos": 844965, "end_pos": 843571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027891.1", "url": "https://www.ensembl.org/id/ENSGALT00010027891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016002.1", "url": "https://www.ensembl.org/id/ENSGALP00010016002.1" } ] } 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"R-GGA-203927", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203927", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-426486", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426486", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-426496", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426496", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSAADKGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "length": 862, "header": "tr|A0A8V0YJ08-1|A0A8V0YJ08_CHICK Isoform 1 of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08/entry", "sequence": { "sequence": "MGSSAADKGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "length": 862, "header": "tr|A0A8V0YJ08-1|A0A8V0YJ08_CHICK Isoform 1 of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "locus": { "chromosome": "23", "start_pos": 4539080, "end_pos": 4523482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036005.1", "url": "https://www.ensembl.org/id/ENSGALT00010036005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020900.1", "url": "https://www.ensembl.org/id/ENSGALP00010020900.1" } ] } }, { "isoform_ac": "A0A8V0YQF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF5/entry", "sequence": { "sequence": "MEISSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVPAVPHTIMFCGMITVLLQMNFSC", "length": 243, "header": "tr|A0A8V0YQF5-1|A0A8V0YJ08_CHICK Computationally mapped isoform of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "locus": { "chromosome": "23", "start_pos": 4543526, "end_pos": 4524311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036014.1", "url": "https://www.ensembl.org/id/ENSGALT00010036014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020907.1", "url": "https://www.ensembl.org/id/ENSGALP00010020907.1" } ] } }, { "isoform_ac": "A0A8V0YQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI4/entry", "sequence": { "sequence": "MNGNQQRREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "length": 804, "header": "tr|A0A8V0YQI4-1|A0A8V0YJ08_CHICK Computationally mapped isoform of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "locus": { "chromosome": "23", "start_pos": 4543530, "end_pos": 4523482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036023.1", "url": "https://www.ensembl.org/id/ENSGALT00010036023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020914.1", "url": "https://www.ensembl.org/id/ENSGALP00010020914.1" } ] } }, { "isoform_ac": "A0A8V0YS52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS52/entry", "sequence": { "sequence": "MEVLAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA", "length": 854, "header": "tr|A0A8V0YS52-1|A0A8V0YJ08_CHICK Computationally mapped isoform of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "locus": { "chromosome": "23", "start_pos": 4537982, "end_pos": 4523482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036001.1", "url": "https://www.ensembl.org/id/ENSGALT00010036001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020897.1", "url": "https://www.ensembl.org/id/ENSGALP00010020897.1" } ] } }, { "isoform_ac": "A0A8V0YX51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX51/entry", "sequence": { "sequence": "MEVLAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPSATHTCAAHDQFLYLHQRIMLTW", "length": 114, "header": "tr|A0A8V0YX51-1|A0A8V0YJ08_CHICK Computationally mapped isoform of Protein argonaute-3 OS=Gallus gallus OX=9031 GN=AGO3 PE=1 SV=1 CANONICAL=A0A8V0YJ08-1" }, "locus": { "chromosome": "23", "start_pos": 4537982, "end_pos": 4524230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035970.1", "url": "https://www.ensembl.org/id/ENSGALT00010035970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020877.1", "url": "https://www.ensembl.org/id/ENSGALP00010020877.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-203927", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203927", "resource": "Reactome", "description": "MicroRNA (miRNA) biogenesis" }, { "id": "R-GGA-426486", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426486", "resource": "Reactome", "description": "Small interfering RNA (siRNA) biogenesis" }, { "id": "R-GGA-426496", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426496", "resource": "Reactome", "description": "Post-transcriptional silencing by small RNAs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by inhibition of translation", "id": "GO:0035278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035278", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "regulation of stem cell proliferation", "id": "GO:0072091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "miRNA binding", "id": "GO:0035198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" }, { "name": "endoribonuclease activity, cleaving miRNA-paired mRNA", "id": "GO:0090624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ08" } ], "pmid": "" 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"glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 427, "end_pos": 429 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJ29-1", "uniprot_ac": "A0A8V0YJ29", "uniprot_id": "A0A8V0YJ29_CHICK", "mass": { "chemical_mass": 88413.0, "monoisotopic_mass": 88413.0 }, "refseq": { "ac": "XP_015144621", "name": "integrin beta-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621" }, "gene_names": [ { "name": "ITGB2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29" } ] }, { "name": "CD18", "type": "synonym", "evidence": [ { "id": "XP_015144621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621" } ] }, { "name": "ITGB2", "type": "synonym", "evidence": [ { "id": "XP_015144621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621" } ] } ], "protein_names": [ { "name": "Integrin beta", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29/entry#names_and_taxonomy" } ] }, { "name": "integrin beta-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015144621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITGB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29", "locus": { "chromosome": "7", "start_pos": 7210759, "end_pos": 7222675, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014976", "url": "https://www.ensembl.org/id/ENSGALG00010014976" } ] } } ], "crossref": [ { "id": "A0A8V0YJ29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ29", "database": "AlphaFoldDB", "categories": [] }, { "id": "396181", "url": "https://www.ncbi.nlm.nih.gov/gene/396181", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ20", "url": "https://www.orthodb.org/?gene=A0A8V0YJ20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ24", "url": 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"R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015144621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144621", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTGKDGAAAPSQNGTAERSPGLCHHDQEMPRDCCLWLPAMTWVLLLLTTAFAAECPKIKVGTCKNCIQSGPGCAWCKKLSFTKAGEPDSNRCDTIEQLQQRGCPENEIEFPVNEIKRTQDSAFSNKIQLTPQEVHLKLRIREPAEFDVKFRRATGYPIDIYYLMDLSYSMLDDLENVKKLGGQLLRALESTTPSRRIGFGSFVDKTVLPFVNTHPEKLKNPCPNKDSNCQPPFAFKHILSLTDNAEKFESEVGKQFISGNLDAPEGGLDAMMQAAVCGDLIGWRNVTRLLVYATDDGFHFAGDGKLGGILTPNDGQCHLEDNMYKKSNEFDYPSVGQLVQKLAENNIQPIFAVTSKMVDVYKKLSDMIPKSAVGELNEDSSNIIELIQVAYNNLSSRIILDHSTLPDVLDVKYDSICNNNTGAKNEARGQCDNVKINDEVTFKVKVTANECIKSQSFTIRPLGFTDTLTVHLDSICDCDCREQPDPTACSGNGKVVCGICSCNLSYTGKNCECDTKGKTSKELEGSCRKDNSSVICSGLGDCVCGQCVCHTSDVPGKEIYGTFCDCDNMNCEFHNGSLCGGEERGRCDCGECKCTPKYEGSACQCKKSTDGCRNSRQNECSLRGSCHCNRCQCRGGYQPPFCEECPGCPSPCGRHISCVECKSFNSGPLAKNCSVACTSIQLADEPRAGSRQCKEKDSENCWISFYMAQDDGEEMYTVTVDPKKECPEPPNIALIVGSTIAGVALIGLLLLLTWRLLTEIFDRREYRRFEKEKSKAKWNEADNPLFKSATTTVMNPRFDGQ", "length": 802, "header": "tr|A0A8V0YJ29-1|A0A8V0YJ29_CHICK Isoform 1 of Integrin beta OS=Gallus gallus OX=9031 GN=ITGB2 PE=1 SV=1 CANONICAL=A0A8V0YJ29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ20/entry", "sequence": { "sequence": "MPRDCCLWLPAMTWVLLLLTTAFAAECPKIKVGTCKNCIQSGPGCAWCKKLSFTKAGEPDSNRCDTIEQLQQRGCPENEIEFPVNEIKRTQDSAFSNKIQLTPQEVHLKLRIREPAEFDVKFRRATGYPIDIYYLMDLSYSMLDDLENVKKLGGQLLRALESTTPSRRIGFGSFVDKTVLPFVNTHPEKLKNPCPNKDSNCQPPFAFKHILSLTDNAEKFESEVGKQFISGNLDAPEGGLDAMMQAAVCGDLIGWRNVTRLLVYATDDGFHFAGDGKLGGILTPNDGQCHLEDNMYKKSNEFDYPSVGQLVQKLAENNIQPIFAVTSKMVDVYKKLSDMIPKSAVGELNEDSSNIIELIQVAYNNLSSRIILDHSTLPDVLDVKYDSICNNNTGAKNEARGQCDNVKINDEVTFKVKVTANECIKSQSFTIRPLGFTDTLTVHLDSICDCDCREQPDPTACSGNGKVVCGICSCNLSYTGKNCECDTKGKTSKELEGSCRKDNSSVICSGLGDCVCGQCVCHTSDVPGKEIYGTFCDCDNMNCEFHNGSLCGGEERGRCDCGECKCTPKYEGSACQCKKSTDGCRNSRQNECSLRGSCHCNRCQCRGGYQPPFCEECPGCPSPCGRHIWLCYSSCVECKSFNSGPLAKNCSVACTSIQLADEPRAGSRQCKEKDSENCWISFYMAQDDGEEMYTVTVDPKKECPEPPNIALIVGSTIAGVALIGLLLLLTWRLLTEIFDRREYRRFEKEKSKAKWNEADNPLFKSATTTVMNPRFDGQ", "length": 778, "header": "tr|A0A8V0YJ20-1|A0A8V0YJ29_CHICK Computationally mapped isoform of Integrin beta OS=Gallus gallus OX=9031 GN=ITGB2 PE=1 SV=1 CANONICAL=A0A8V0YJ29-1" }, "locus": { "chromosome": "7", "start_pos": 7217886, "end_pos": 7211691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036026.1", "url": "https://www.ensembl.org/id/ENSGALT00010036026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020915.1", "url": "https://www.ensembl.org/id/ENSGALP00010020915.1" } ] } }, { "isoform_ac": "A0A8V0YJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ24/entry", "sequence": { "sequence": 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142953" }, "gene_names": [ { "name": "KDM7A", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ] }, { "name": "KDM7A", "type": "synonym", "evidence": [ { "id": "XP_015142953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142953" } ] } ], "protein_names": [ { "name": "Lysine-specific demethylase 7A", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28/entry#names_and_taxonomy" } ] }, { "name": "JmjC domain-containing histone demethylation protein 1D", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28/entry#names_and_taxonomy" } ] }, { "name": "Lysine-specific demethylase 7", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28/entry#names_and_taxonomy" } ] }, { "name": "lysine-specific demethylase 7A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015142953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142953.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142953" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KDM7A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28", "locus": { "chromosome": "1", "start_pos": 56720299, "end_pos": 56776576, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013316", "url": "https://www.ensembl.org/id/ENSGALG00010013316" } ] } } ], "crossref": [ { "id": "A0A8V0YJ28", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ28", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15640", 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Lysine-specific demethylase 7A OS=Gallus gallus OX=9031 GN=KDM7A PE=3 SV=1 CANONICAL=A0A8V0YJ28-1" }, "locus": { "chromosome": "1", "start_pos": 56776562, "end_pos": 56722425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032034.1", "url": "https://www.ensembl.org/id/ENSGALT00010032034.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018824.1", "url": "https://www.ensembl.org/id/ENSGALP00010018824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "histone H3K36 demethylase activity", "id": 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"GO:0032452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "histone H3K27me2/H3K27me3 demethylase activity", "id": "GO:0071558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "histone H3K9me/H3K9me2 demethylase activity", "id": "GO:0140683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ28" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJ63-1", "uniprot_ac": "A0A8V0YJ63", "uniprot_id": "A0A8V0YJ63_CHICK", "mass": { "chemical_mass": 113871.0, "monoisotopic_mass": 113871.0 }, "refseq": { "ac": "XP_417710", "name": "guanylate-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417710" }, "gene_names": [ { "name": "GBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ63" } ] }, { "name": "GBP1", "type": "synonym", "evidence": [ { "id": "XP_417710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417710" } ] } ], "protein_names": [ { "name": "Guanylate binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ63", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417710.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417710" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ63", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJ63", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ63", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ95/entry#names_and_taxonomy" } ] }, { "name": "avidin-related protein 1", "type": "synonym", "evidence": [ { "id": "XP_040512439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512439" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512439" } ] }, { "annotation": "Forms a strong non-covalent specific complex with biotin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ95#function" }, { "database": "UniProtKB", "id": "RU369114", "url": "https://www.uniprot.org/uniprotkb/RU369114#function" }, { "database": "UniProtKB", "id": "ARBA00059199", "url": "https://www.uniprot.org/uniprotkb/ARBA00059199#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus 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"id": "IPR051764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TYYLCAL", "url": "https://omabrowser.org/oma/group/TYYLCAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ95", "url": "https://www.orthodb.org/?gene=A0A8V0YJ95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34399:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34399:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040512439", "url": 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displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. 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Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9#function" }, { "database": "UniProtKB", "id": "ARBA00045425", "url": "https://www.uniprot.org/uniprotkb/ARBA00045425#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYLY", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01561", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01561", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04608", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04608", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJF9", "url": "https://www.orthodb.org/?gene=A0A8V0YJF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10314", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10314", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1614603", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10112", "url": "https://www.rhea-db.org/rhea/10112", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMETAKACLLMNGSCMGSQESKADSGWILPNLPSKCTWTAATPANKSPHSCIPLSEETKILPNILKKIGSTPMVRVNKIGKSYGLKCELLAKCEYFNAGGSVKDRISLRMVEDAERAGIIKPGDTLIEPTSGNTGIGLALVAAVKGYRCIIVLPEKMSMEKVDILKALGVEIVRTPCTRFDAPESNIRVAWKLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCEGKVHMVVIGSGTGGTVTGVARKLKEKCPECKIIGVDPEGSIVALPSELNRTNNITVEVEGIGHDFIPTVLDRSVVDQWYKCNDRDSFLMSRRLIREEGLLCGGSSGSAMSVAVQAAKDLKDGQRCVVILPDSVRNYMSKFLNDKWMIKNGFLNDVQEHKPWWWNIKVQKLNLSAPLILLPEVSCQKAIEILREKGYDQAPVVAESGLILGMVTLSNTLTSVLAGSAQFSDPVTKVIYDQFSKISLEDSLGKLSCILENDHFAIVVHEQMQLGMAVPS", "length": 507, "header": "tr|A0A8V0YJF9-1|A0A8V0YJF9_CHICK Isoform 1 of Cystathionine beta-synthase OS=Gallus gallus OX=9031 GN=CYLY PE=3 SV=1 CANONICAL=A0A8V0YJF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9/entry", "sequence": { "sequence": "MAEMETAKACLLMNGSCMGSQESKADSGWILPNLPSKCTWTAATPANKSPHSCIPLSEETKILPNILKKIGSTPMVRVNKIGKSYGLKCELLAKCEYFNAGGSVKDRISLRMVEDAERAGIIKPGDTLIEPTSGNTGIGLALVAAVKGYRCIIVLPEKMSMEKVDILKALGVEIVRTPCTRFDAPESNIRVAWKLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCEGKVHMVVIGSGTGGTVTGVARKLKEKCPECKIIGVDPEGSIVALPSELNRTNNITVEVEGIGHDFIPTVLDRSVVDQWYKCNDRDSFLMSRRLIREEGLLCGGSSGSAMSVAVQAAKDLKDGQRCVVILPDSVRNYMSKFLNDKWMIKNGFLNDVQEHKPWWWNIKVQKLNLSAPLILLPEVSCQKAIEILREKGYDQAPVVAESGLILGMVTLSNTLTSVLAGSAQFSDPVTKVIYDQFSKISLEDSLGKLSCILENDHFAIVVHEQMQLGMAVPS", "length": 507, "header": "tr|A0A8V0YJF9-1|A0A8V0YJF9_CHICK Isoform 1 of Cystathionine beta-synthase OS=Gallus gallus OX=9031 GN=CYLY PE=3 SV=1 CANONICAL=A0A8V0YJF9-1" }, "locus": { "chromosome": "1", "start_pos": 109774865, "end_pos": 109755998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028240.1", "url": "https://www.ensembl.org/id/ENSGALT00010028240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016179.1", "url": "https://www.ensembl.org/id/ENSGALP00010016179.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1614603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614603", "resource": "Reactome", "description": "Cysteine formation from homocysteine" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" }, { "name": "cystathionine beta-synthase activity", "id": "GO:0004122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cysteine biosynthetic process from serine", "id": "GO:0006535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" }, { "name": "cysteine biosynthetic process via cystathionine", "id": "GO:0019343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019343", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" }, { "name": "homocysteine metabolic process", "id": "GO:0050667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10112", "name": "", "equation": "L-homocysteine + L-serine = L,L-cystathionine + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y6C9-1", "A0A8V0YJF9-1" ], "evidence": [ { "id": "10112", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10112" } ] }, { "id": "R-GGA-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-174369", "R-ALL-200736" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJF9-1" ], "evidence": [ { "id": "R-GGA-1614524", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614524" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-174369", "participant_name": "HCYS [cytosol]", "crossref": [ { "id": "58199", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895077", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-200736", "participant_name": "L-Ser [cytosol]", "crossref": [ { "id": "33384", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895034", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y6C9", "gene_name": "CBS", "activity": [ { "ec_number": "4.2.1.22", "activity": "L-homocysteine + L-serine = L,L-cystathionine + H2O.", "evidence": [ { "id": "A0A8V0Y6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6C9" } ] }, { "ec_number": "4.2.1.22", "activity": "", "evidence": [ { "id": "A0A8V0Y6C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6C9" } ] } ] }, { "uniprot_ac": "A0A8V0YJF9", "gene_name": "CYLY", "activity": [ { "ec_number": "4.2.1.22", "activity": "L-homocysteine + L-serine = L,L-cystathionine + H2O.", "evidence": [ { "id": "A0A8V0YJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ] }, { "ec_number": "4.2.1.22", "activity": "", "evidence": [ { "id": "A0A8V0YJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF9" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 401, "end_pos": 457, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.22", "ec_name": "L-homocysteine + L-serine = L,L-cystathionine + H2O.", "evidence": [ { "id": "4.2.1.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.22" }, { "id": "4.2.1.22", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.22" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 44, 132 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJG4-1", "uniprot_ac": "A0A8V0YJG4", "uniprot_id": "A0A8V0YJG4_CHICK", "mass": { "chemical_mass": 36295.0, "monoisotopic_mass": 36295.0 }, "refseq": { "ac": "NP_001026173", "name": "3-ketodihydrosphingosine reductase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" }, "gene_names": [ { "name": "KDSR", "type": "recommended", "evidence": [ { "id": "A0A8V0YJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ] }, { "name": "FVT1", "type": "synonym", "evidence": [ { "id": "NP_001026173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" } ] }, { "name": "KDSR", "type": "synonym", "evidence": [ { "id": "NP_001026173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" } ] } ], "protein_names": [ { "name": "3-dehydrosphinganine reductase", "type": "recommended", "evidence": [ { "id": "A0A8V0YJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.102", "type": "synonym", "evidence": [ { "id": "A0A8V0YJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4/entry#names_and_taxonomy" } ] }, { "name": "3-ketodihydrosphingosine reductase", "type": "synonym", "evidence": [ { "id": "NP_001026173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" } ] }, { "name": "follicular lymphoma variant translocation 1", "type": "synonym", "evidence": [ { "id": "NP_001026173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.6517.1, AJ719938.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000040.1. On or before Dec 11, 2020 this sequence version replaced XP_015137662.1, NP_001026173.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173" } ] }, { "annotation": "Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4#function" }, { "database": "UniProtKB", "id": "ARBA00044737", "url": "https://www.uniprot.org/uniprotkb/ARBA00044737#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KDSR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4", "locus": { "chromosome": "2", "start_pos": 67572902, "end_pos": 67552409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011817", "url": "https://www.ensembl.org/id/ENSGALG00010011817" } ] } } ], "crossref": [ { "id": "A0A8V0YJG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420902", "url": "https://www.ncbi.nlm.nih.gov/gene/420902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICGVFEE", "url": "https://omabrowser.org/oma/group/ICGVFEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJG4", "url": "https://www.orthodb.org/?gene=A0A8V0YJG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43550:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43550:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22640", "url": "https://www.rhea-db.org/rhea/22640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLAAAFIVAIVLLLYMVSPLISPKPLKLPGAHVVVTGGSSGIGKCIAIECYKQGAFITLIARDENKLLQTKKEIEKYSVNDKQVVLCISVDVSKDYEQVENVLKQAQEKLGPVDLLVNCAGTSVTGKFEDIEVNSFERLMAVNYLGSVYPSRAVISTMKERRMGRIVFVSSQAGQLGLFGYTAYSPTKFALRGLAEALQMEVKPYNIYVTVAYPPDTDTPGFAEESKTKPLETKLISETSSVCQAEQVARVIVKDAIQGNFNSSVGSDGYMLSILTSGMSPVTSITEGLQQVVCMGIFRIVGLFYLGSFDSIVRRCMMQREKSENTDKTE", "length": 332, "header": "tr|A0A8V0YJG4-1|A0A8V0YJG4_CHICK Isoform 1 of 3-dehydrosphinganine reductase OS=Gallus gallus OX=9031 GN=KDSR PE=1 SV=1 CANONICAL=A0A8V0YJG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4/entry", "sequence": { "sequence": "MLLLAAAFIVAIVLLLYMVSPLISPKPLKLPGAHVVVTGGSSGIGKCIAIECYKQGAFITLIARDENKLLQTKKEIEKYSVNDKQVVLCISVDVSKDYEQVENVLKQAQEKLGPVDLLVNCAGTSVTGKFEDIEVNSFERLMAVNYLGSVYPSRAVISTMKERRMGRIVFVSSQAGQLGLFGYTAYSPTKFALRGLAEALQMEVKPYNIYVTVAYPPDTDTPGFAEESKTKPLETKLISETSSVCQAEQVARVIVKDAIQGNFNSSVGSDGYMLSILTSGMSPVTSITEGLQQVVCMGIFRIVGLFYLGSFDSIVRRCMMQREKSENTDKTE", "length": 332, "header": "tr|A0A8V0YJG4-1|A0A8V0YJG4_CHICK Isoform 1 of 3-dehydrosphinganine reductase OS=Gallus gallus OX=9031 GN=KDSR PE=1 SV=1 CANONICAL=A0A8V0YJG4-1" }, "locus": { "chromosome": "2", "start_pos": 67569603, "end_pos": 67552565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028248.1", "url": "https://www.ensembl.org/id/ENSGALT00010028248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016184.1", "url": "https://www.ensembl.org/id/ENSGALP00010016184.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420902", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SMW5-1", "protein_name": "3-ketodihydrosphingosine reductase", "gene_name": "KDSR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSVNYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAEENKTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQRARSEIADKTA", "length": 332 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HD45-1", "protein_name": "3-ketodihydrosphingosine reductase", "gene_name": "Kdsr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLLLAAAGLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCVAIECFKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSLSGKFEELEVSAFEKLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAKENKTKPLETRLISETTSICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRIIALFYLGSFDNIVRRCMVKKAKPETVDKTA", "length": 332 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q06136-1", "protein_name": "3-ketodihydrosphingosine reductase", "gene_name": "KDSR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA", "length": 332 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WRJ2-1", "protein_name": "3-dehydrosphinganine reductase TSC10A", "gene_name": "TSC10A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAISPLFLLFLIPIIPLSLLAILALIVRPRPIKIPIKSRHAFITGGSSGIGLALAHRAASEGARVSILARSGSKLEEAKKSIQLATGVEVATFSADVRDYDAVSKAIDESGPIDVLIVNQGVFTAKELVKHSPEDVKFTIDVNLVGSFNVIKAALPAMKARKDRGPASISLVSSQAGQVGVYGYAAYSASKFGLQGLAQALQQEVISDDIHVTLIFPPDTNTPGFEEEQKSRPEVTAIIAASSGSMETEEVAKKAMDGIKAGNFTVSCNFEGFLLSLATTGMSPQRSFWLAFLEVITAGPIRLIALFFQWDWYKAIEKWSKTKTK", "length": 326 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q2KIJ5-1", "protein_name": "3-ketodihydrosphingosine reductase", "gene_name": "KDSR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLLAAASLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSINYLGSVYPSRAVIATMKERRMGRVVFVSSQAGQLGLFGYTAYSSSKFALRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAKENQTKPLETRLISETTSVCKPEQVAKQIVKDAVQGNFNSSIGSDGYMLSSLTCGMAPVTSIMEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQKAKLETVDKTA", "length": 332 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6GV12-1", "protein_name": "3-ketodihydrosphingosine reductase", "gene_name": "Kdsr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLAAAGLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSMSGKFEELEVSSFEKLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAEENKTKPLETRLISETTAICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDNIVRRCMVQKAKPEVVDKTA", "length": 332 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VBU5-1", "protein_name": "3-dehydrosphinganine reductase", "gene_name": "Kdsr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MELSWEIVFCVGIAVLVHVLVYVFVMAKKPRSIVGRHVVVTGGSKGIGLCLAVECAMKGANVTVIARDEKMLSGAVALMEVIRQRPDQKFQYRSLDISGDYDQVAKVLGEIEDSFGPIYTLINCAGMAICGVFEEVSVQDVHKLMNVNFFGTYNCTRYVLPKMKKAGDGIIVITASQAAMFGIYGYGPYSATKYALRAMAETIAMESREHGVSVTLAMPCDTNTPGFEEEEKSKPRETKIISGGGGLIEPEVMAKAILKDALKGKFTSTVGAESWLITTLGGALLPWDGFFTNLLHAIVLGPLRIVSYALHKYFNSVIRKCAREDKAKATSQVESK", "length": 336 }, "evidence": [ { "id": "A0A8V0YJG4", "url": "https://omabrowser.org/oma/group/A0A8V0YJG4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "3-keto-sphinganine metabolic process", "id": "GO:0006666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" }, { "name": "sphingomyelin biosynthetic process", "id": "GO:0006686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" }, { "name": "glycosphingolipid biosynthetic process", "id": "GO:0006688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "3-dehydrosphinganine reductase activity", "id": "GO:0047560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22640", "name": "", "equation": "sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJG4-1" ], "evidence": [ { "id": "22640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22640" } ] }, { "id": "R-GGA-428123", "name": "KDSR reduces 3-ketosphingoid", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-9841798" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJG4-1" ], "evidence": [ { "id": "R-GGA-428123", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428123" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9841798", "participant_name": "3-ketosphingoid [endoplasmic reticulum membrane]", "crossref": [ { "id": "84411", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJG4", "gene_name": "KDSR", "activity": [ { "ec_number": "1.1.1.102", "activity": "sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+).", "evidence": [ { "id": "A0A8V0YJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ] }, { "ec_number": "1.1.1.102", "activity": "", "evidence": [ { "id": "A0A8V0YJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.102", "ec_name": "sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+).", "evidence": [ { "id": "1.1.1.102", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.102" }, { "id": "1.1.1.102", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.102" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142900.1. 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"https://www.genome.jp/dbget-bin/www_bget?gga:418114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNCIIAT", "url": "https://omabrowser.org/oma/group/FNCIIAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH0", "url": "https://www.orthodb.org/?gene=A0A8V0YJH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK48", "url": "https://www.orthodb.org/?gene=A0A8V0YK48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42909:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42909:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAKISCRLARRVSTEAHRTTQVRRFLHGAYFRIQPSIQEALVEGRPVVALESTIITHGMAYPQNLSMAREVEKIVMRNGAVPATIGILKGQIHVGLTDEELQFLASSKNVVKVSRRDLPYVLSQGLSGGTTVSGTMIAAHKAGIPVFVTGGIGGVHRGGENTLDVSADLTELGRTPVAVVSAGVKSILDIGRTLEYLETQGVCVAAFGESRMFPAFFSSQSGFQAPYRVQDEEEAAKLIASTLGLGLSSGVLIAVPCPQEQAAPGQLIEDAIQQALSEARSKGITGKELTPFLLQKINELTNGKSLDSNLALIQNNARVGSGIAVALSKLQKATRKGSLPRRGDTTLPQPVVIGGTNVDFIAKAQNSVILGGGQTNAGRVRRTFGGVGRNLADCLSRLGLTPLFLSAVGKDEHSESILHYCHHMDMSAILQLEGKSTATYSAMITSAGELSIGLGDMDIHQQITEQYVSQFKENLCRAPLVCIDGNVPLSTIQYICQLARDHQLAVCYEPTDENKASKPFLSDSWKALTYISPNLQELKAINRTLGNPLPAEAPSRLEDIIKMAAALARPLLSHLCCVVVTLGAHGVLLCGRSLGGSISLRPAPHEQTAAASLCATHYPAIPISREEIVNVSGAGDSLMAGIAAGMLANHDTDTCVRMGLLAARFSLCSYEPISPEISTSTVSQEQVQSKPWPEVKVWKLD", "length": 702, "header": "tr|A0A8V0YK48-1|A0A8V0YK48_CHICK Isoform 1 of Carbohydrate kinase PfkB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418114 PE=3 SV=1 CANONICAL=A0A8V0YK48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH0/entry", "sequence": { "sequence": "MIAKISCRLARRVSTEAHRTTQVRRFLHGAYFRIQPSIQEALVEGRPVVALESTIITHGMAYPQNLSMAREVEKIVMRNGAVPATIGILKGQIHVGLTDEELQFLASSKNVVKVSRRDLPYVLSQGLSGGTTVSGTMIAAHKAGIPVFVTGGIGGVHRGGENTLDVSADLTELGRTPVAVVSAGVKSILDIGRTLEYLETQGVCVAAFGESRMFPAFFSSQSGFQAPYRVQDEEEAAKLIASTLGLGLSSGVLIAVPCPQEQAAPGQLIEDAIQQALSEARSKGITGKELTPFLLQKINELTNGKSLDSNLALIQNNARVGSGIAVALSKLQKATRKGSLPRRGDTTLPQPVVIGGTNVDFIAKAQNSVILGGGQTNAGRVRRTFGGVGRNLADCLSRLGLTPLFLSAVGKDEHSESILHYCHHMDMSAILQLEGKSTATYSAMITSAGELSIGLGDMDIHQQITEQYVSQFKENLCRAPLVCIDGNVPLSTIQYICQLARDHQLAEAPSRLEDIIKMAAALARPLLSHLCCVVVTLGAHGVLLCGRSLGGSISLRPAPHEQTAAASLCATHYPAIPISREEIVNVSGAGDSLMAGIAAGMLANHDTDTCVRMGLLAARFSLCSYEPISPEISTSTVSQEQVQSKPWPEVKVWKLD", "length": 656, "header": "tr|A0A8V0YJH0-1|A0A8V0YK48_CHICK Computationally mapped isoform of Carbohydrate kinase PfkB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418114 PE=3 SV=1 CANONICAL=A0A8V0YK48-1" }, "locus": { "chromosome": "1", "start_pos": 56874479, "end_pos": 56851357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032170.1", "url": "https://www.ensembl.org/id/ENSGALT00010032170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018960.1", "url": "https://www.ensembl.org/id/ENSGALP00010018960.1" } ] } }, { "isoform_ac": "A0A8V0YK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48/entry", "sequence": { "sequence": "MIAKISCRLARRVSTEAHRTTQVRRFLHGAYFRIQPSIQEALVEGRPVVALESTIITHGMAYPQNLSMAREVEKIVMRNGAVPATIGILKGQIHVGLTDEELQFLASSKNVVKVSRRDLPYVLSQGLSGGTTVSGTMIAAHKAGIPVFVTGGIGGVHRGGENTLDVSADLTELGRTPVAVVSAGVKSILDIGRTLEYLETQGVCVAAFGESRMFPAFFSSQSGFQAPYRVQDEEEAAKLIASTLGLGLSSGVLIAVPCPQEQAAPGQLIEDAIQQALSEARSKGITGKELTPFLLQKINELTNGKSLDSNLALIQNNARVGSGIAVALSKLQKATRKGSLPRRGDTTLPQPVVIGGTNVDFIAKAQNSVILGGGQTNAGRVRRTFGGVGRNLADCLSRLGLTPLFLSAVGKDEHSESILHYCHHMDMSAILQLEGKSTATYSAMITSAGELSIGLGDMDIHQQITEQYVSQFKENLCRAPLVCIDGNVPLSTIQYICQLARDHQLAVCYEPTDENKASKPFLSDSWKALTYISPNLQELKAINRTLGNPLPAEAPSRLEDIIKMAAALARPLLSHLCCVVVTLGAHGVLLCGRSLGGSISLRPAPHEQTAAASLCATHYPAIPISREEIVNVSGAGDSLMAGIAAGMLANHDTDTCVRMGLLAARFSLCSYEPISPEISTSTVSQEQVQSKPWPEVKVWKLD", "length": 702, "header": "tr|A0A8V0YK48-1|A0A8V0YK48_CHICK Isoform 1 of Carbohydrate kinase PfkB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418114 PE=3 SV=1 CANONICAL=A0A8V0YK48-1" }, "locus": { "chromosome": "1", "start_pos": 56874479, "end_pos": 56851357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032168.1", "url": "https://www.ensembl.org/id/ENSGALT00010032168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018958.1", "url": "https://www.ensembl.org/id/ENSGALP00010018958.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418114", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q55FH2-1", "protein_name": "Carbohydrate kinase PfkB domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFKIIYFIILSIIVSYFSKIGIDYYFSSDEIKERYSLFEYVVNDQIIKFGSNRDRDLFDRSHYNEEVFYNIKISKEVQDALRYGKPIVSLESTIISHGMPFPQNYETALEVESIVRSYGVIPATIAILNGTIHIGLTEKEIHYLATVGKDAIKTSRRDIAMVTSMGKTGSTTVSATILFSNLVGIKVFVTGGLGGVHRGAETSLDVSADLTELGKNGVMVVSAGVKSILDIGKTLEYLETQGVTVVTFGSDEFPAFFTKHSGVKTPNRLDTVDQCAKLLYSNQLLQLKSGMVVAVPPRDNEHSELIDRAIKESIEQSKVDGILGKDITPYLLKKVNEKTGGKSLESNIELVKNNARIGSQISKHYYNLLKNKQSPTSSTTTIKGDELVFNYFDQRVNTFLRNYFKTLSAETLLLNGPNKLKGLNGPKPNKQLADNHIEYDIVVVGGAVIDMISHPFKESGFQMETSNPGAISIKMGGVGRNVAEVLSRLQMNSLFISLVGDDVHSGLLMESFQKMNLSSNGVGIKVGSKTAIYNAIMNDRGDLAVAIAQMDIFDEITPSYISKFDLTSSKLLVFDGNIPIESMTYLAQLSRSKGIKLWFEPTSVYKSSKIVESFILSSITYISPNRDELIKISNEIIKKGLIKFENIINNDINDLENIKKHSIILIESGIKYIITKMGSKGVLLAYKKDDGEFKFELFSAPEVPDNKIVDVTGAGDSLVGCTIYSILLGHNLTTAIPQYGTPCAKESLLSTNPVSPNIKISLFK", "length": 765 }, "evidence": [ { "id": "A0A8V0YK48", "url": "https://omabrowser.org/oma/group/A0A8V0YK48/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VPR3-1", "protein_name": "Carbohydrate kinase PfkB domain-containing protein", "gene_name": "Dmel\\CG2794", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLRRCFLFPFPAVRLVRRSLHRKHDHIVLHPEIRQALQLQKPVVALESTIITHGMPMPENVVTALAVEEQVRQNGAIPATIGILDGRIKVGLTREELTSLAEKPRDQVIKCSRRDLPFVVSRRQSGGTTVAATMIIAHRVGIHVFATGGIGGVHRDGHESMDVSADLTELGRTPVAVVCSGVKSILDIPRTLEFLETQGVCVASFDSPGGVFPDFYTRDSGCTVPYNLKSAQEAAELLRSWRELKMESGLVIGVPIPEEFAADKFKIEEAIKEATAQARAQGISGKEVTPFLLAAIAKITEGRSLKSNIALIKNNAKVAAQIAASLCDVSTKLESPVQKAIDKKPLVVGASILDLSFKVDDQKRDMKLDGATYSAVAKQAAGGVGRNIAEGIYKLYGDVNLISAVGNDQMGQTLLQMMPKALKRGLIVADNHNTSLCSLIFDKFGDCKLILGNMEIHQSITAETLQAHHQLFREAPLIIMDSNISEQAMASILQQAQINKIPVFFEPTDMFIAGKPFKLLPELTKNIRLIKPNMQELKTITEAITGETVKWNPETKQPQTELVQQAKSLIKKIDSHFNCIIATLSDHGVLLSYRGDAENDARLLLDVSKPTPPHSTRFYPAPMVHNIVNVSGAGDSFCAGFITALLRGRSLDECIAGGFVAAERALQSESAVPATYFSNQESFESRYKHTARIIQQQSI", "length": 700 }, "evidence": [ { "id": "A0A8V0YK48", "url": "https://omabrowser.org/oma/group/A0A8V0YK48/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" }, { "name": "hydrolase activity, acting on glycosyl bonds", "id": "GO:0016798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016798", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" }, { "name": "pseudouridylate synthase activity", "id": "GO:0004730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleoside phosphate metabolic process", "id": "GO:0006753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006753", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YK48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK48" }, { "id": "PF00294", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase PfkB", "eco_id": "ECO_0000259", "start_pos": 352, "end_pos": 676, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 543, "end_pos": 545 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJH2-1", "uniprot_ac": "A0A8V0YJH2", "uniprot_id": "A0A8V0YJH2_CHICK", "mass": { "chemical_mass": 23213.0, "monoisotopic_mass": 23213.0 }, "refseq": {}, "gene_names": [ { "name": "RFK", "type": "recommended", "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ] } ], "protein_names": [ { "name": "riboflavin kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.26", "type": "synonym", "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV3#function" }, { "database": "UniProtKB", "id": "ARBA00054097", "url": "https://www.uniprot.org/uniprotkb/ARBA00054097#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RFK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2", "locus": { "chromosome": "Z", "start_pos": 37947448, "end_pos": 37953998, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015064", "url": "https://www.ensembl.org/id/ENSGALG00010015064" } ] } } ], "crossref": [ { "id": "A0A8V0YJH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR015865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH2", "url": "https://www.orthodb.org/?gene=A0A8V0YJH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQV3", "url": "https://www.orthodb.org/?gene=A0A8V0YQV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSL5", "url": "https://www.orthodb.org/?gene=A0A8V0YSL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22749", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22749", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22749:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22749:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196843", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14357", "url": "https://www.rhea-db.org/rhea/14357", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SNKCRRRRQNTDHQQQRPQRPAPALTRKPSSWLWASPSVGGGRPLTERPPARKLGHSACSPLRVVVPRTRKKRGPGAAVANFSEQVVESFPSDIPTGIYYGWASVGNGDVHKMVLSIGWNPFYKNIKKSVETHIINTFKEDFYGEILSIVITGYIRSEKNFNSLETLVSAIREDIEEAKRQLDLPEHLKLKDNFFDLPEGKIVNH", "length": 205, "header": "tr|A0A8V0YJH2-1|A0A8V0YJH2_CHICK Isoform 1 of riboflavin kinase OS=Gallus gallus OX=9031 GN=RFK PE=4 SV=1 CANONICAL=A0A8V0YJH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2/entry", "sequence": { "sequence": "SNKCRRRRQNTDHQQQRPQRPAPALTRKPSSWLWASPSVGGGRPLTERPPARKLGHSACSPLRVVVPRTRKKRGPGAAVANFSEQVVESFPSDIPTGIYYGWASVGNGDVHKMVLSIGWNPFYKNIKKSVETHIINTFKEDFYGEILSIVITGYIRSEKNFNSLETLVSAIREDIEEAKRQLDLPEHLKLKDNFFDLPEGKIVNH", "length": 205, "header": "tr|A0A8V0YJH2-1|A0A8V0YJH2_CHICK Isoform 1 of riboflavin kinase OS=Gallus gallus OX=9031 GN=RFK PE=4 SV=1 CANONICAL=A0A8V0YJH2-1" }, "locus": { "chromosome": "Z", "start_pos": 37953928, "end_pos": 37950290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036252.1", "url": "https://www.ensembl.org/id/ENSGALT00010036252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021076.1", "url": "https://www.ensembl.org/id/ENSGALP00010021076.1" } ] } }, { "isoform_ac": "A0A8V0YQV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV3/entry", "sequence": { "sequence": "MRGRCAAAVRYLPYFCRGEVVKGFGRGSRELGVPTVESFPSDIPTGIYYGWASVGNGDVHKMVLSIGWNPFYKNIKKSVETHIINTFKEDFYGEILSIVITGYIRSEKNFNSLETLVSAIREDIEEAKRQLDLPEHLKLKDNFFDLPEGKIVNH", "length": 154, "header": "tr|A0A8V0YQV3-1|A0A8V0YJH2_CHICK Computationally mapped isoform of riboflavin kinase OS=Gallus gallus OX=9031 GN=RFK PE=4 SV=1 CANONICAL=A0A8V0YJH2-1" }, "locus": { "chromosome": "Z", "start_pos": 37953663, "end_pos": 37950290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036249.1", "url": "https://www.ensembl.org/id/ENSGALT00010036249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021073.1", "url": "https://www.ensembl.org/id/ENSGALP00010021073.1" } ] } }, { "isoform_ac": "A0A8V0YSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSL5/entry", "sequence": { "sequence": "SNKCRRRRQNTDHQQQRPQRPAPALTRKPSSWLWASPSVGGGRPLTERPPARKLGHSACSPLRVVVPRTRKKRGPGAAVGRWSVDVAGHAGPVCSRREETHIINTFKEDFYGEILSIVITGYIRSEKNFNSLETLVSAIREDIEEAKRQLDLPEHLKLKDNFFDLPEGKIVNH", "length": 173, "header": "tr|A0A8V0YSL5-1|A0A8V0YJH2_CHICK Computationally mapped isoform of riboflavin kinase OS=Gallus gallus OX=9031 GN=RFK PE=4 SV=1 CANONICAL=A0A8V0YJH2-1" }, "locus": { "chromosome": "Z", "start_pos": 37953928, "end_pos": 37950290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036250.1", "url": "https://www.ensembl.org/id/ENSGALT00010036250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021074.1", "url": "https://www.ensembl.org/id/ENSGALP00010021074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-196843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196843", "resource": "Reactome", "description": "Vitamin B2 (riboflavin) metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "riboflavin kinase activity", "id": "GO:0008531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "riboflavin biosynthetic process", "id": "GO:0009231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009231", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "FMN biosynthetic process", "id": "GO:0009398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" }, { "name": "riboflavin metabolic process", "id": "GO:0006771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14357", "name": "", "equation": "riboflavin + ATP = FMN + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YZM4-1", "A0A8V0YJH2-1" ], "evidence": [ { "id": "14357", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14357" } ] }, { "id": "R-GGA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-196931" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJH2-1" ], "evidence": [ { "id": "R-GGA-196964", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196964" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-196931", "participant_name": "RIB [cytosol]", "crossref": [ { "id": "57986", "database": "ChEBI", "url": "" }, { "id": "ZINC000002036848", "database": "ZINC", "url": "" }, { "id": "C00255", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJH2", "gene_name": "RFK", "activity": [ { "ec_number": "2.7.1.26", "activity": "riboflavin + ATP = FMN + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ] }, { "ec_number": "2.7.1.26", "activity": "", "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" } ] } ] }, { "uniprot_ac": "A0A8V0YZM4", "gene_name": "RFKL", "activity": [ { "ec_number": "2.7.1.26", "activity": "riboflavin + ATP = FMN + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM4" } ] }, { "ec_number": "2.7.1.26", "activity": "", "evidence": [ { "id": "A0A8V0YZM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH2" }, { "id": "SM00904", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Riboflavin kinase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 183, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.26", "ec_name": "riboflavin + ATP = FMN + ADP + H(+).", "evidence": [ { "id": "2.7.1.26", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.26" }, { "id": "2.7.1.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.26" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJJ1-1", "uniprot_ac": "A0A8V0YJJ1", "uniprot_id": "A0A8V0YJJ1_CHICK", "mass": { "chemical_mass": 73369.0, "monoisotopic_mass": 73369.0 }, "refseq": { "ac": "XP_414568", "name": "tyrosine-protein kinase ITK/TSK", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414568" }, "gene_names": [ { "name": "ITK", "type": "recommended", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "name": "ITK", "type": "synonym", "evidence": [ { "id": "XP_414568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414568" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein kinase ITK/TSK", "type": "synonym", "evidence": [ { "id": "XP_414568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_414568.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1", "locus": { "chromosome": "13", "start_pos": 11020451, "end_pos": 11048454, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015076", "url": "https://www.ensembl.org/id/ENSGALG00010015076" } ] } } ], "crossref": [ { "id": "A0A8V0YJJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10396", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10396", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11908", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11908", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416247", "url": "https://www.ncbi.nlm.nih.gov/gene/416247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416247", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYWLEKT", "url": "https://omabrowser.org/oma/group/GYWLEKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YJJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202433", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWERTILCPVMNNCVLLEEQLIKKSQQKRRTSPSNFKVRFFVLTKSKLAYYEHRHGKKRTLKGYVELSRIKCVEIVKSDIIIPCQYKYPFQIVHDNYILYVFAPNRESRQRWVFTLKEETRSNNSLVSKYHPDFWIDGKWRCCAQTEKMAVGCIEYDPTKTASKKPLPPTPEDNWKSLLNTKETLVMAIYDYEAQNPQELTLQYNEEYHVIDSSEEHWWLIQDKNGHEGYVPSSYLAEKSPENLQIYEWYNKNINRSKAEMLLRDEGREGAFMVRDSRQPGMYTVSVFTKALSTDNNPVIKHYHINETTDFPKRYYLAEKHVFNCIPELINYHQHNAGGLVTRLRYAVSSWKKKAPITAGLSYGKLVINPSELTRVQEIGSGQFGVVYLGYWLEKTKVAIKTIREGAMSEEDFIEEAKVLMKLSHPKLVQLYGVCFENTPICLVFEFMEHGCLSDYLRSQRGSFSKETLLGMCLDVCEGMAYLEQNSVIHRDLAARNCLVGESQVVKVSDFGMSRIVLDDQYTSSTGTKFPVKWSAPEVFSYSNYSTKSDVWSFGVLMWEVFSEGKMPYENRTNGEVVEEINAGFRLYKPKLASKAIYEVMSHCWSMRKEDRPSFSLLLYQLSEISEFDP", "length": 631, "header": "tr|A0A8V0YJJ1-1|A0A8V0YJJ1_CHICK Isoform 1 of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=ITK PE=3 SV=1 CANONICAL=A0A8V0YJJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1/entry", "sequence": { "sequence": "MSWERTILCPVMNNCVLLEEQLIKKSQQKRRTSPSNFKVRFFVLTKSKLAYYEHRHGKKRTLKGYVELSRIKCVEIVKSDIIIPCQYKYPFQIVHDNYILYVFAPNRESRQRWVFTLKEETRSNNSLVSKYHPDFWIDGKWRCCAQTEKMAVGCIEYDPTKTASKKPLPPTPEDNWKSLLNTKETLVMAIYDYEAQNPQELTLQYNEEYHVIDSSEEHWWLIQDKNGHEGYVPSSYLAEKSPENLQIYEWYNKNINRSKAEMLLRDEGREGAFMVRDSRQPGMYTVSVFTKALSTDNNPVIKHYHINETTDFPKRYYLAEKHVFNCIPELINYHQHNAGGLVTRLRYAVSSWKKKAPITAGLSYGKLVINPSELTRVQEIGSGQFGVVYLGYWLEKTKVAIKTIREGAMSEEDFIEEAKVLMKLSHPKLVQLYGVCFENTPICLVFEFMEHGCLSDYLRSQRGSFSKETLLGMCLDVCEGMAYLEQNSVIHRDLAARNCLVGESQVVKVSDFGMSRIVLDDQYTSSTGTKFPVKWSAPEVFSYSNYSTKSDVWSFGVLMWEVFSEGKMPYENRTNGEVVEEINAGFRLYKPKLASKAIYEVMSHCWSMRKEDRPSFSLLLYQLSEISEFDP", "length": 631, "header": "tr|A0A8V0YJJ1-1|A0A8V0YJJ1_CHICK Isoform 1 of Tyrosine-protein kinase OS=Gallus gallus OX=9031 GN=ITK PE=3 SV=1 CANONICAL=A0A8V0YJJ1-1" }, "locus": { "chromosome": "13", "start_pos": 11048419, "end_pos": 11020766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036281.1", "url": "https://www.ensembl.org/id/ENSGALT00010036281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021097.1", "url": "https://www.ensembl.org/id/ENSGALP00010021097.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416247", "resource": "KEGG Pathway" }, { "id": "R-GGA-202433", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "resource": "Reactome", "description": "Generation of second messenger molecules" }, { "id": "R-GGA-2871809", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "resource": "Reactome", "description": "FCERI mediated Ca+2 mobilization" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7W7-1", "protein_name": "Tyrosine-protein kinase", "gene_name": "Itk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQTLTSFQVMHDNYLLYVFAPDCESRQRWVLTLKEETRNNNSLVSKYHPNFWMDGRWRCCSQLEKLAVGCAPYDPTKNASKKPLPPTPEDNRRSFQEPEETLVIALYDYQTNDPQELALRRDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNSLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENNPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHVYQVMNHCWKEKPEDRPPFSRLLSQLAEIAECGL", "length": 626 }, "evidence": [ { "id": "A0A8V0YJJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YJJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03526-1", "protein_name": "Tyrosine-protein kinase ITK/TSK", "gene_name": "Itk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQTLVYLQVVHDNYLLYVFAPDCESRQRWVLTLKEETRNNNSLVSKYHPNFWMDGRWRCCSQLEKPAVGCAPYDPSKNASKKPLPPTPEDNRRSFQEPEETLVIALYDYQTNDPQELALRCDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAEAGL", "length": 625 }, "evidence": [ { "id": "A0A8V0YJJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YJJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08881-1", "protein_name": "Tyrosine-protein kinase ITK/TSK", "gene_name": "ITK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL", "length": 620 }, "evidence": [ { "id": "A0A8V0YJJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YJJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "gamma-delta T cell activation", "id": "GO:0046629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" }, { "name": "NK T cell differentiation", "id": "GO:0001865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-202248", "name": "Phosphorylation of PLC-gamma1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZHR0-1", "A0A8V0YJJ1-1" ], "evidence": [ { "id": "R-GGA-202248", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202248" } ] }, { "id": "R-GGA-2730833", "name": "Phosphorylation of TEC kinases by p-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XHW1-1", "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1NZY8-1", "A0A8V0YYC1-1", "F1N9Y5-1", "A0A8V0YJJ1-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-2730833", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730833" } ] }, { "id": "R-GGA-2730847", "name": "Hydrolysis of PIP2 by PLCG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-112275" ], "enzyme_list": [ "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1NZY8-1", "A0A8V0YYC1-1", "A0A8V0YJJ1-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-2730847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730847" } ] }, { "id": "R-GGA-2730858", "name": "Autophosphorylation of BTK/ITK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHP4-1", "A0A8V0ZHR0-1", "F1NZY8-1", "A0A8V0YYC1-1", "A0A8V0YJJ1-1", "A0A8V0YUJ4-1" ], "evidence": [ { "id": "R-GGA-2730858", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730858" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-112275", "participant_name": "DAGs [plasma membrane]", "crossref": [ { "id": "C00165", "database": "COMPOUND", "url": "" }, { "id": "18035", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PHP4", "gene_name": "PLCG2", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": 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+ ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] } ] }, { "uniprot_ac": "A0A8V0YKP8", "gene_name": "VEGFRKDRL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YPR4", "gene_name": 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"uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZHR0", "gene_name": "PLCG1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + 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"Protein" ] }, { "id": "A0A8V0YJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TVENVKLLDRYTNRKAASGTLYLTATHLIYVDASAEVRKETWILHHHIATVEKLPLTTAGCPLLIHCKNFHVAHFVIGQERDCHEVYTSLLKLSQPVKPEELYAFSYNPKMSKDNREIGWKLIDLKVDYQRMGIPNDYWEITDLNKDYEVCNTYPPEIVVPRAASKATVIGSSRFRSRGRIPVLSYLYKENNAAICRCSQPLSGFSARCLEDEQMLQAIREANPGSPFMYVVDTRPKLNAMANRAAGKGYENEDNYDNIRFKFIGIENIHVMRSSLQKLLEVCETKSPSMSDFLTGLENSGWLRHIKAVMDASVFLAKAVKDEKASVLVHCSDGWDRTAQVCSLASLLLDPFYRTFKGFMVLIEKEWIAMGHKFSHRCGHLDGDPKEVSPVFTQFIECVWQLMQQFPCTFEFNEHFLLEIHDHVYSCQFGNFLGTCHKEREDLKIFEKTHSLWPFLLQKKQELRNPLYRGFTAYKELQPNTLPFSFQFWCGMYNRFDKGMHPKQCVLDHLLSCMNQKIKLEDNASELENKLPFLDGPLPNEACFLSKVGCAASKTPMLNTPQDYEGEAPPVLTNGISVGDINVTSDVDQRNKENLANHRDLHLNDSVDVLNSEAKDGKPQHH", "length": 622, "header": "tr|A0A8V0YJJ7-1|A0A8V0YJJ7_CHICK Isoform 1 of Myotubularin related protein 8 OS=Gallus gallus OX=9031 GN=MTMR8 PE=3 SV=1 CANONICAL=A0A8V0YJJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7/entry", "sequence": { "sequence": "TVENVKLLDRYTNRKAASGTLYLTATHLIYVDASAEVRKETWILHHHIATVEKLPLTTAGCPLLIHCKNFHVAHFVIGQERDCHEVYTSLLKLSQPVKPEELYAFSYNPKMSKDNREIGWKLIDLKVDYQRMGIPNDYWEITDLNKDYEVCNTYPPEIVVPRAASKATVIGSSRFRSRGRIPVLSYLYKENNAAICRCSQPLSGFSARCLEDEQMLQAIREANPGSPFMYVVDTRPKLNAMANRAAGKGYENEDNYDNIRFKFIGIENIHVMRSSLQKLLEVCETKSPSMSDFLTGLENSGWLRHIKAVMDASVFLAKAVKDEKASVLVHCSDGWDRTAQVCSLASLLLDPFYRTFKGFMVLIEKEWIAMGHKFSHRCGHLDGDPKEVSPVFTQFIECVWQLMQQFPCTFEFNEHFLLEIHDHVYSCQFGNFLGTCHKEREDLKIFEKTHSLWPFLLQKKQELRNPLYRGFTAYKELQPNTLPFSFQFWCGMYNRFDKGMHPKQCVLDHLLSCMNQKIKLEDNASELENKLPFLDGPLPNEACFLSKVGCAASKTPMLNTPQDYEGEAPPVLTNGISVGDINVTSDVDQRNKENLANHRDLHLNDSVDVLNSEAKDGKPQHH", "length": 622, "header": "tr|A0A8V0YJJ7-1|A0A8V0YJJ7_CHICK Isoform 1 of Myotubularin related protein 8 OS=Gallus gallus OX=9031 GN=MTMR8 PE=3 SV=1 CANONICAL=A0A8V0YJJ7-1" }, "locus": { "chromosome": "4", "start_pos": 11603652, "end_pos": 11585423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032196.1", "url": "https://www.ensembl.org/id/ENSGALT00010032196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018985.1", "url": "https://www.ensembl.org/id/ENSGALP00010018985.1" } ] } }, { "isoform_ac": "A0A8V0YJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK2/entry", "sequence": { "sequence": "MEHITTPKVENVKLLDRYTNRKAASGTLYLTATHLIYVDASAEVRKETWILHHHIATVEKLPLTTAGCPLLIHCKNFHVAHFVIGQERDCHEVYTSLLKLSQPVKPEELYAFSYNPKMSKDNREIGWKLIDLKVDYQRMGIPNDYWEITDLNKDYEVCNTYPPEIVVPRAASKATVIGSSRFRSRGRIPVLSYLYKENNLNAMANRAAGKGYENEDNYDNIRFKFIGIENIHVMRSSLQKLLEVCETKSPSMSDFLTGLENSGWLRHIKAVMDASVFLAKAVKDEKASVLVHCSDGWDRTAQVCSLASLLLDPFYRTFKGFMVLIEKEWIAMGHKFSHRCGHLDGDPKEVSPVFTQFIECVWQLMQQFPCTFEFNEHFLLEIHDHVYSCQFGNFLGTCHKEREDLKIFEKTHSLWPFLLQKKQELRNPLYRGFTAYKELQPNTLPFSFQFWCGMYNRFDKGMHPKQCVLDHLLSCMNQKIKLEDNASELENKLPFLDGPLPNEACFLSKVGCAASKTPMLNTPQDYEGEAPPVLTNGISVGDINVTSDVDQRNKENLANHRDLHLNDSVDVLNSEAKDGKPQHH", "length": 584, "header": "tr|A0A8V0YJK2-1|A0A8V0YJK2_CHICK Computationally mapped isoform of Myotubularin related protein 8 OS=Gallus gallus OX=9031 GN=MTMR8 PE=3 SV=1 CANONICAL=A0A8V0YJJ7-1" }, "locus": { "chromosome": "4", "start_pos": 11603652, "end_pos": 11584633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032200.1", "url": "https://www.ensembl.org/id/ENSGALT00010032200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018990.1", "url": "https://www.ensembl.org/id/ENSGALP00010018990.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-3,5-bisphosphate phosphatase activity", "id": "GO:0106018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of macroautophagy", "id": "GO:0016241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016241", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ7" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 493, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 523, "end_pos": 525 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 604, "end_pos": 606 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJK9-1", "uniprot_ac": "A0A8V0YJK9", "uniprot_id": "A0A8V0YJK9_CHICK", "mass": { "chemical_mass": 56245.0, "monoisotopic_mass": 56245.0 }, "refseq": {}, "gene_names": [ { "name": "GABRA3", "type": "recommended", "evidence": [ { "id": "A0A8V0YJK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ] } ], "protein_names": [ { "name": "Gamma-aminobutyric acid type A receptor subunit alpha3", "type": "synonym", "evidence": [ { "id": "A0A8V0YJK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GABRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9", "locus": { "chromosome": "4", "start_pos": 10758279, "end_pos": 10668781, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015087", "url": "https://www.ensembl.org/id/ENSGALG00010015087" } ] } } ], "crossref": [ { "id": "A0A8V0YJK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19036", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19036", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422289", "url": "https://www.ncbi.nlm.nih.gov/gene/422289", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422289", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422289", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJK4", "url": "https://www.orthodb.org/?gene=A0A8V0YJK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJK9", "url": "https://www.orthodb.org/?gene=A0A8V0YJK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-977443", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977443", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPATHLQRRGGGEREWLWRLACCSLCTEAMAPRLTGMASLSLAVLGLLLSAVPADAGLSQKHVSDVVDDSKDNITIFTRILDRLLDGYDNRLRPGLGDSVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWRDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKTEVIYTWTLGKDKSVEVAKGGSRLNQYDLLGHVVGTEMVRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKVLEAQEMKKKEPVALVKKTNNTYNIVGTTYPLNIAKDPGLPTISKSAAATATATNVPPKMPRLEEKLPESKKTYNSVSKVDKMSRIVFPVLFAIFNLVYWATYVNRESAIKGMIPKQ", "length": 501, "header": "tr|A0A8V0YJK9-1|A0A8V0YJK9_CHICK Isoform 1 of Gamma-aminobutyric acid type A receptor subunit alpha3 OS=Gallus gallus OX=9031 GN=GABRA3 PE=3 SV=1 CANONICAL=A0A8V0YJK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK4/entry", "sequence": { "sequence": "MAPRLTGMASLSLAVLGLLLSAVPADAGLSQKHVSDVVDDSKDNITIFTRILDRLLDGYDNRLRPGLGDSVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWRDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKTEVIYTWTLGKDKSVEVAKGGSRLNQYDLLGHVVGTEMVRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKVLEAQEMKKKEPVALVKKTNNTYNIVGTTYPLNIAKDPGLPTISKSAAATATATNVPPKMPRLEEKLPESKKTYNSVSKVDKMSRIVFPVLFAIFNLVYWATYVNRESAIKGMIPKQ", "length": 471, "header": "tr|A0A8V0YJK4-1|A0A8V0YJK9_CHICK Computationally mapped isoform of Gamma-aminobutyric acid type A receptor subunit alpha3 OS=Gallus gallus OX=9031 GN=GABRA3 PE=3 SV=1 CANONICAL=A0A8V0YJK9-1" }, "locus": { "chromosome": "4", "start_pos": 10758055, "end_pos": 10709429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036311.1", "url": "https://www.ensembl.org/id/ENSGALT00010036311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021114.1", "url": "https://www.ensembl.org/id/ENSGALP00010021114.1" } ] } }, { "isoform_ac": "A0A8V0YJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9/entry", "sequence": { "sequence": "MAPATHLQRRGGGEREWLWRLACCSLCTEAMAPRLTGMASLSLAVLGLLLSAVPADAGLSQKHVSDVVDDSKDNITIFTRILDRLLDGYDNRLRPGLGDSVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWRDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKTEVIYTWTLGKDKSVEVAKGGSRLNQYDLLGHVVGTEMVRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKVLEAQEMKKKEPVALVKKTNNTYNIVGTTYPLNIAKDPGLPTISKSAAATATATNVPPKMPRLEEKLPESKKTYNSVSKVDKMSRIVFPVLFAIFNLVYWATYVNRESAIKGMIPKQ", "length": 501, "header": "tr|A0A8V0YJK9-1|A0A8V0YJK9_CHICK Isoform 1 of Gamma-aminobutyric acid type A receptor subunit alpha3 OS=Gallus gallus OX=9031 GN=GABRA3 PE=3 SV=1 CANONICAL=A0A8V0YJK9-1" }, "locus": { "chromosome": "4", "start_pos": 10758055, "end_pos": 10668980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036317.1", "url": "https://www.ensembl.org/id/ENSGALT00010036317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021119.1", "url": "https://www.ensembl.org/id/ENSGALP00010021119.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422289", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422289", "resource": "KEGG Pathway" }, { "id": "R-GGA-977443", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977443", "resource": "Reactome", "description": "GABA receptor activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "GABA-A receptor complex", "id": "GO:1902711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "GABA-A receptor activity", "id": "GO:0004890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "GABA-gated chloride ion channel activity", "id": "GO:0022851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022851", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" }, { "name": "inhibitory synapse assembly", "id": "GO:1904862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" }, { "id": "PF02931", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel ligand-binding", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 286, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK9" }, { "id": "PF02932", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel transmembrane", "eco_id": "ECO_0000259", "start_pos": 293, "end_pos": 385, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJN0-1", "uniprot_ac": "A0A8V0YJN0", "uniprot_id": "A0A8V0YJN0_CHICK", "mass": { "chemical_mass": 58410.0, "monoisotopic_mass": 58410.0 }, "refseq": { "ac": "XP_417826", "name": "sodium-dependent lysophosphatidylcholine symporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417826" }, "gene_names": [ { "name": "MFSD2A", "type": "recommended", "evidence": [ { "id": "A0A8V0YJN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ] }, { "name": "MFSD2A", "type": "synonym", "evidence": [ { "id": "XP_417826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417826" } ] } ], "protein_names": [ { "name": "MFSD2 lysolipid transporter A, lysophospholipid", "type": "synonym", "evidence": [ { "id": "A0A8V0YJN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent lysophosphatidylcholine symporter 1", "type": "synonym", "evidence": [ { "id": "XP_417826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417826" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417826.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417826" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0", "locus": { "chromosome": "23", "start_pos": 5911055, "end_pos": 5903278, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015097", "url": "https://www.ensembl.org/id/ENSGALG00010015097" } ] } } ], "crossref": [ { "id": "A0A8V0YJN0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "419679", "url": "https://www.ncbi.nlm.nih.gov/gene/419679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419679", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419679", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFAIGFN", "url": "https://omabrowser.org/oma/group/AFAIGFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJN0", "url": "https://www.orthodb.org/?gene=A0A8V0YJN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXS5", "url": "https://www.orthodb.org/?gene=A0A8V0YXS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "43856", "url": "https://www.rhea-db.org/rhea/43856", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43860", "url": "https://www.rhea-db.org/rhea/43860", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43864", "url": "https://www.rhea-db.org/rhea/43864", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43868", "url": "https://www.rhea-db.org/rhea/43868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44376", "url": "https://www.rhea-db.org/rhea/44376", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGGGAERVRVGAAAAGLLPPSCRQPRRRESRERLSVCSKLCYAVGGAPYQTTGCALGFFLQIYLLDVAQLDPFYASIILFVGRAWDAITDPMVGFFISKTPWTRFGRLMPWIIFSTPFAVISYFLIWFVPDISTGQVMWYLIFYCIFQTLVTCFHVPYSALTMFISREQSERDSATAYRMTVEVLGTVLGTAIQGQIVGKAVTPCIETPPFLSETNFSVAIRNVNMTHYTGSLADTRNAYMVAAGVIGGLYILCAVILSVGVREKRESSELQSDEPVSFFRGLKLVMNHGAYIKLITGFLFTSLAFMLLEGNFALFCTYTLGFRNEFQNILLAIMLSATLTIPFWQWFLTRFGKKTAVYVGISSAVPFLITVVVLDSNLVVTYIVAVAAGISVAAAFLLPWSMLPDVIDDFKLQHPESRGHEAIFFSFYVFFTKFTSGVSLGISTLSLDFAGYQTRGCSQPSEVNITLKLLVSAVPVGLILLGLLLFKLYPIDEEKRRENKKALQDLREESNSSSESDSTELANIV", "length": 528, "header": "tr|A0A8V0YJN0-1|A0A8V0YJN0_CHICK Isoform 1 of MFSD2 lysolipid transporter A, lysophospholipid OS=Gallus gallus OX=9031 GN=MFSD2A PE=3 SV=1 CANONICAL=A0A8V0YJN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0/entry", "sequence": { "sequence": "MAGGGGAERVRVGAAAAGLLPPSCRQPRRRESRERLSVCSKLCYAVGGAPYQTTGCALGFFLQIYLLDVAQLDPFYASIILFVGRAWDAITDPMVGFFISKTPWTRFGRLMPWIIFSTPFAVISYFLIWFVPDISTGQVMWYLIFYCIFQTLVTCFHVPYSALTMFISREQSERDSATAYRMTVEVLGTVLGTAIQGQIVGKAVTPCIETPPFLSETNFSVAIRNVNMTHYTGSLADTRNAYMVAAGVIGGLYILCAVILSVGVREKRESSELQSDEPVSFFRGLKLVMNHGAYIKLITGFLFTSLAFMLLEGNFALFCTYTLGFRNEFQNILLAIMLSATLTIPFWQWFLTRFGKKTAVYVGISSAVPFLITVVVLDSNLVVTYIVAVAAGISVAAAFLLPWSMLPDVIDDFKLQHPESRGHEAIFFSFYVFFTKFTSGVSLGISTLSLDFAGYQTRGCSQPSEVNITLKLLVSAVPVGLILLGLLLFKLYPIDEEKRRENKKALQDLREESNSSSESDSTELANIV", "length": 528, "header": "tr|A0A8V0YJN0-1|A0A8V0YJN0_CHICK Isoform 1 of MFSD2 lysolipid transporter A, lysophospholipid OS=Gallus gallus OX=9031 GN=MFSD2A PE=3 SV=1 CANONICAL=A0A8V0YJN0-1" }, "locus": { "chromosome": "23", "start_pos": 5910749, "end_pos": 5903344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036347.1", "url": "https://www.ensembl.org/id/ENSGALT00010036347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021140.1", "url": "https://www.ensembl.org/id/ENSGALP00010021140.1" } ] } }, { "isoform_ac": "A0A8V0YXS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXS5/entry", "sequence": { "sequence": "MAGGGGAERVRVGAAAAGLLPPSCRQPRRRESRERLSVCSKLCYAVGGAPYQTTGCALGFFLQIYLLDVAQLDPFYASIILFVGRAWDAITDPMVGFFISKTPWTRFGRLMPWIIFSTPFAVISYFLIWFVPDISTGQVMWYLIFYCIFQTLVTCFHVPYSALTMFISREQSERDSATAYRMTVEVLGTVLGTAIQGQIVGKAVTPCIETPPFLSETNFSVAIRNVNMTHYTGSLADTRNAYMVAAGVIGGLYILCAVILSVGVREKRESSELQSDEPVSFFRGLKLVMNHGAYIKLITGFLFTSLAFMLSATLTIPFWQWFLTRFGKKTAVYVGISSAVPFLITVVVLDSNLVVTYIVAVAAGISVAAAFLLPWSMLPDVIDDFKLQHPESRGHEAIFFSFYVFFTKFTSGVSLGISTLSLDFAGYQTRGCSQPSEVNITLKLLVSAVPVGLILLGLLLFKLYPIDEEKRRENKKALQDLREESNSSSESDSTELANIV", "length": 500, "header": "tr|A0A8V0YXS5-1|A0A8V0YJN0_CHICK Computationally mapped isoform of MFSD2 lysolipid transporter A, lysophospholipid OS=Gallus gallus OX=9031 GN=MFSD2A PE=3 SV=1 CANONICAL=A0A8V0YJN0-1" }, "locus": { "chromosome": "23", "start_pos": 5910749, "end_pos": 5903344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036341.1", "url": "https://www.ensembl.org/id/ENSGALT00010036341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021135.1", "url": "https://www.ensembl.org/id/ENSGALP00010021135.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419679", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419679", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "resource": "Reactome", "description": "Synthesis of PC" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WBW6-1", "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1", "gene_name": "Mfsd2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGEGAESGSAAGLLPTGILQASERPAQVKEPKKKQQLSICNKLCYAVGGAPYQLTGCALGFFLQIYLLDVAKVEPLPASIILFVGRAWDAFTDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIAYFLIWFVPDFPSGTESSHGFLWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMTVEVLGTVIGTAIQGQIVGQAKAPCLQDQNGSAVASEVVNRTQSTASLKETQNAYLLAAGIIASIYVICAVILILGVREQREPYEAQQAESMPFFQGLRLVMSHGPYVKLIAGFLFTSLAFMLVEGNFALFCTYTLGFRNEFQNLLLAIMLSATFTIPIWQWFLTRFGKKTAVYVGISSAVPFLILVALMKSNLIVTYVVAIAAGVSVAAAFLLPWSMLPDVIDDFHLKHPHSPGTEPIFFSFYVFFTKFASGVSLGVSTLSLDFAKYQTQGCSQPEEVKFTLKMLVTMAPIILILLGLLLFKLYPIDEEKRRQNKKALQALRDEASSSGCSDTDSTELASIL", "length": 533 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SMC3-1", "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1", "gene_name": "MFSD2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKGEGAESGSAAGLLPTGILQAGERPVQVKKEPKKQKQLSVCNKLCYAVGGAPYQVTGCALGFFLQIYLLDVAQVDPFSASIILFVGRAWDAITDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIAYFLIWFVPDFKQGQALWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMTVEVLGTVLGTAIQGQIVGQADTPCIQDVNASTVASEGVNLTQSATSLKETQNAYLLAAGVIASIYVICAIILILGVREQREPYETQQTKPMSFFPGLRLVMSHGPYIKLIAGFLFTSLAFMLVEGNFALFCTYTLGFRNEFQNLLLAIMLSATITIPIWQWFLTRFGKKMAVYIGISSAVPFLILVALMESNLIVTYVVAVAAGISVAAAFLLPWSMLPDVIDDFHLKQPHIHGTEPIFFSFYVFFTKFASGVSLGISTLSLDFTGYQTRGCSQPARVKFTLKMLVTMAPIVLILLGLLLFKLYPIDEEKRRQNKKALQALREEASSSGCSETDSTELASIL", "length": 529 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54SX3-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSGNSGIPLDTTKEYVDTTTLLRNKQNLKQYSFNIGNSGGSPNLTEKYNENTKLLNNNKNNNNGKYKLSFSEKFSYGIGEGGLSVFQMIKGFFLNSFLLNVAQIDSMFTAVILFTAKFVDAFSDVLVGNLSDKTKSRWGRRRVWILFGSLPFAILYCGLWWVPPNLTDVERLIYYQFVVIGLSIAYTCVAIPYSAMNAEITDDYDERTTLAGIRMISLMIGGLTSTFTHSLIIKIFTTQTANGSEYIDYRKGYLLSGGIWGGVMIIPLFITFFGTRKIPIESQTESHIPFFKGLGVMFSNRAFVTVTLLYFFCQIAVQFVQNNLLLYCTYVADAEKEFPYILATLQISVSIFIFVWGKISTYIGKKVTYYIGGVFLLLSFLSLFFLPYGSKYLLWGVAAFGGIGVAVAFLIPMSMLPDVVELDELKTGERREGLFYSLFLFFQKLGLSVGLAVSSFVLGLVGYEAPTQIDSSQGISAEIIDNNIENDNVIFALRILTGLAPAVIVLFSFVAIFFYPISKQSHNEIRELLKRKREGTVTITVDEK", "length": 544 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DEJ6-1", "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1-B", "gene_name": "mfsd2ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKGEGAEQYTNTSLLQKPSPDEVKLAKHETKSRLSVCSKLCYAIGGAPYQITGCAIGFFLQIYLLDVALLDPFYASIILFVGRAWDAVTDPTVGFLVSRTPWTRFGRMMPWIVLSTPFAVLCYFLIWYVPSVDQGKVVWYLIFYCCFQTLQTCFHVPYSALTMFISTEQKERDSATAYRMTVEVLGTLIGTAIQGQIVGMANAPCISTEIDLNSTGLEVAPDVNITDPHVSLQDLRNAYMIASGVICAIYVVCAVVLFLGVKEQKDTCRVRTEPMSFFQGICMVMGHGPYAKLVMGFLFTSLAFMLLEGNFALFCIYNLGFRNDFQNVLLVIMLSATLAIPFWQWFLTKFGKKTAVYIGTTSVVPFLISVVLVPSSLAVTYIASFAAGVSVAAAFLLPWSMLPDVVDDFKVQNPESQGHEAIFYSFYVFFTKFASGVSLGVSTLSLDFAGYVTRGCTQPGEVKLTLKILVSAAPIVLIIIGLLIFISYPINEEKRQGNRKLLNEQRENEMDSETDSTELNVV", "length": 523 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8NA29-1", "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1", "gene_name": "MFSD2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKGEGAESGSAAGLLPTSILQSTERPAQVKKEPKKKKQQLSVCNKLCYALGGAPYQVTGCALGFFLQIYLLDVAQKDEEVVFCFSSFQVGPFSASIILFVGRAWDAITDPLVGLCISKSPWTCLGRLMPWIIFSTPLAVIAYFLIWFVPDFPHGQTYWYLLFYCLFETMVTCFHVPYSALTMFISTEQTERDSATAYRMTVEVLGTVLGTAIQGQIVGQADTPCFQDLNSSTVASQSANHTHGTTSHRETQKAYLLAAGVIVCIYIICAVILILGVREQREPYEAQQSEPIAYFRGLRLVMSHGPYIKLITGFLFTSLAFMLVEGNFVLFCTYTLGFRNEFQNLLLAIMLSATLTIPIWQWFLTRFGKKTAVYVGISSAVPFLILVALMESNLIITYAVAVAAGISVAAAFLLPWSMLPDVIDDFHLKQPHFHGTEPIFFSFYVFFTKFASGVSLGISTLSLDFAGYQTRGCSQPERVKFTLNMLVTMAPIVLILLGLLLFKMYPIDEERRRQNKKALQALRDEASSSGCSETDSTELASIL", "length": 543 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DA75-1", "protein_name": "Sodium-dependent lysophosphatidylcholine symporter 1", "gene_name": "Mfsd2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKGEGAESGSAAGLLPTSILQASERPVQVKKEPKKKQQLSICNKLCYAVGGAPYQLTGCALGFFLQIYLLDVAKVEPLPASIILFVGRAWDAFTDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIAYFLIWFVPDFPSGTESSHGFLWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMTVEVLGTVIGTAIQGQIVGQAKAPCLQDQNGSVVVSEVANRTQSTASLKDTQNAYLLAAGIIASIYVLCAFILILGVREQRELYESQQAESMPFFQGLRLVMGHGPYVKLIAGFLFTSLAFMLVEGNFALFCTYTLDFRNEFQNLLLAIMLSATFTIPIWQWFLTRFGKKTAVYIGISSAVPFLILVALMERNLIVTYVVAVAAGVSVAAAFLLPWSMLPDVIDDFHLKHPHSPGTEPIFFSFYVFFTKFASGVSLGVSTLSLDFANYQRQGCSQPEQVKFTLKMLVTMAPIILILLGLLLFKLYPIDEEKRRQNKKALQALREEASSSGCSDTDSTELASIL", "length": 534 }, "evidence": [ { "id": "A0A8V0YJN0", "url": "https://omabrowser.org/oma/group/A0A8V0YJN0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "fatty acid transmembrane transporter activity", "id": "GO:0015245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "lysophospholipid:sodium symporter activity", "id": "GO:0051978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "lysophosphatidylcholine flippase activity", "id": "GO:0140348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140348", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "oleate transmembrane transporter activity", "id": "GO:1901480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "lipid transport across blood-brain barrier", "id": "GO:1990379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "establishment of blood-brain barrier", "id": "GO:0060856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "carbohydrate transport", "id": "GO:0008643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "transcytosis", "id": "GO:0045056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "lysophospholipid translocation", "id": "GO:0140329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140329", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "lysophospholipid transport", "id": "GO:0051977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43856", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43856", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43856" } ] }, { "id": "43860", "name": "", "equation": "1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43860", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43860" } ] }, { "id": "43864", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) = 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43864", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43864" } ] }, { "id": "43868", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + Na(+)(in) = a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43868", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43868" } ] }, { "id": "44376", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) = a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "44376", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44376" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 205 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJP3-1", "uniprot_ac": "A0A8V0YJP3", "uniprot_id": "A0A8V0YJP3_CHICK", "mass": { "chemical_mass": 76766.0, "monoisotopic_mass": 76766.0 }, "refseq": { "ac": "XP_015134022", "name": "cyclic nucleotide-gated olfactory channel isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134022" }, "gene_names": [ { "name": "CNGA2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3" } ] }, { "name": "CNGA2", "type": "synonym", "evidence": [ { "id": "XP_015134022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134022" } ] } ], "protein_names": [ { "name": "Cyclic nucleotide gated channel subunit alpha 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3/entry#names_and_taxonomy" } ] }, { "name": "cyclic nucleotide-gated olfactory channel isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134022.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3", "locus": { "chromosome": "4", "start_pos": 10865748, "end_pos": 10872219, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015104", "url": "https://www.ensembl.org/id/ENSGALG00010015104" } ] } } ], "crossref": [ { "id": "A0A8V0YJP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771609", "url": "https://www.ncbi.nlm.nih.gov/gene/771609", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771609", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771609", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWYYHWL", "url": "https://omabrowser.org/oma/group/DWYYHWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP3", "url": "https://www.orthodb.org/?gene=A0A8V0YJP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45638:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45638:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMARSNGLQLPGPCPPLPTRARTDAQSTELSTSRTHSTQDETLELHRGTPAYGGEQLAAPPFQGRQALARIVRLVMVLRDWASKSLQEEQQRPDPFLERFQGPELQTVPADAISGPEDEEAEEKTKKKKWQSFVVDPARDWYYRWLAVIAVPVLYNWCLLVARACFSDLQKTYVVLWLVLDYISDCIYIGDIVISLRTGFLEQGLLVKDLKKLRDNYIYTLQFKLDVLSILPTDLAYFAVGLHHPELRFNRLLHFSRMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKAIGFGEDSWVYPNVTDPEYGYLTREYVYCLYWSTLTLTTIGETPPPVRDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAIKHYMQFRKVSKDMETKVIKWFDYLWTNKKAVDEREVLKSLPDKLRAEIAINVHLETLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGTTQYALLTAGGCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKEDLMEVVTEYPDAKKVLEERGREILIKEGLLDESAEEESMEGKSVEEKLDRLTLNLDTLHTRLGRLLTEYSDAQMKLKQRITVLESQMRQQDLEDFFSDSSDSLSEVGGEATPAGL", "length": 671, "header": "tr|A0A8V0YJP3-1|A0A8V0YJP3_CHICK Isoform 1 of Cyclic nucleotide gated channel subunit alpha 2 OS=Gallus gallus OX=9031 GN=CNGA2 PE=3 SV=1 CANONICAL=A0A8V0YJP3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP3/entry", "sequence": { "sequence": "MMARSNGLQLPGPCPPLPTRARTDAQSTELSTSRTHSTQDETLELHRGTPAYGGEQLAAPPFQGRQALARIVRLVMVLRDWASKSLQEEQQRPDPFLERFQGPELQTVPADAISGPEDEEAEEKTKKKKWQSFVVDPARDWYYRWLAVIAVPVLYNWCLLVARACFSDLQKTYVVLWLVLDYISDCIYIGDIVISLRTGFLEQGLLVKDLKKLRDNYIYTLQFKLDVLSILPTDLAYFAVGLHHPELRFNRLLHFSRMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKAIGFGEDSWVYPNVTDPEYGYLTREYVYCLYWSTLTLTTIGETPPPVRDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAIKHYMQFRKVSKDMETKVIKWFDYLWTNKKAVDEREVLKSLPDKLRAEIAINVHLETLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGTTQYALLTAGGCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKEDLMEVVTEYPDAKKVLEERGREILIKEGLLDESAEEESMEGKSVEEKLDRLTLNLDTLHTRLGRLLTEYSDAQMKLKQRITVLESQMRQQDLEDFFSDSSDSLSEVGGEATPAGL", "length": 671, "header": "tr|A0A8V0YJP3-1|A0A8V0YJP3_CHICK Isoform 1 of Cyclic nucleotide gated channel subunit alpha 2 OS=Gallus gallus OX=9031 GN=CNGA2 PE=3 SV=1 CANONICAL=A0A8V0YJP3-1" }, "locus": { "chromosome": "4", "start_pos": 10872020, "end_pos": 10866752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036368.1", "url": "https://www.ensembl.org/id/ENSGALT00010036368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021155.1", "url": "https://www.ensembl.org/id/ENSGALP00010021155.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 667, "start_aa": "Thr", "end_pos": 667, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr667", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771609", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771609", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SYL5-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "CNGA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTEKANGVKSSPANHNHHAPPTIKANGKDDHRTSSRPQSAADDDTSSELQRLAELDAPQRGRGGFRRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTQQGDGKGDKDGEGKATKKKFELFVLDPAGDWYYRWLFVIALPVLYNWCLLVARACFSDLQKGYYIAWLVLDYFSDVVYIIDLLIRLRTGFLEQGLLVRDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHRPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVNVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSDGMNSPEPAAAENP", "length": 663 }, "evidence": [ { "id": "A0A8V0YJP3", "url": "https://omabrowser.org/oma/group/A0A8V0YJP3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MBN0-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "CNGA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEKANGVKSSPANNHNHHAPPAIKASGKDDHRASSRPQSAADDDTSSELQRLAEMDAPQQRRGGFRRIARLVGVLREWAYRNFREEEPRPDSFLERFRGPELHTVTTQQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFLIALPVLYNWCLLVARACFSDLQKGYYIVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTMQFKLDVASIIPTDLIYFAVGIHNPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLILYILIIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLSREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKRVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDSLSDGMNSPEPPAEKP", "length": 663 }, "evidence": [ { "id": "A0A8V0YJP3", "url": "https://omabrowser.org/oma/group/A0A8V0YJP3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P92960-1", "protein_name": "Potassium channel KAT3", "gene_name": "KAT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTTTTEARSPLPLLLRRGRSSTALSASTAEARSPLSILQFRRRSSKDVRNITSVSSSLLPAFGTFIEDDNPSSKPFIVLHFDRRYRLWELFLVILVGYSAWASLFELAFEKAAEGALLTIDLVVDFFFAVDIILTFFVSYLDNTTYLNVTDHKLIAKRYLKSVAFVMDVASTLPIQFIYKTITGDVGRGQAFGFLNLLRLWRLRRVAELFKRLEKDAHFNYFVIRVIKLLCVTIFWIHLAGCILYWIAYHYPRPTDTWIGSQVEDFKERSVWLGYTYSMYWSIVTLTTVGYGDLHAVNSREKTFNMFYMLFNIGLTSYIIGIMTNLVVHGALRTFAMRSAINDILRYTSKNRLPDTMREQMLAHMQLKFKTAELRQEEVLQDLPKAIRSSINQHLFRSIIEEAYLFKGFPEGLLVQLVSQIQAEYFPPKMEIILQNEIPTDFYVIVSGGVDIIASKGVSEQVLAKLGPGSMAGEIGVVFNIPQPFTVRTRRLSQVIRIGHHKFKEMVQSDNDVDAKMIIANFMTYLKGLNDELKKEIPFLRDLLDDADAQVQETVQSEETPQSNDEEIVTVSRHENGQIEERRREGVPKRVIIHGQAPPNQDNKNNGDSNGRLIILPDSIQLLFDLAEKKLGKRGSTIAMADGAHVEQIDALRENDHLYIF", "length": 662 }, "evidence": [ { "id": "A0A8V0YJP3", "url": "https://omabrowser.org/oma/group/A0A8V0YJP3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q00195-1", "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "Cnga2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSPELQRLAEMDTPRRGRGGFQRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDDKGGKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYVISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPTAAE", "length": 664 }, "evidence": [ { "id": "A0A8V0YJP3", "url": "https://omabrowser.org/oma/group/A0A8V0YJP3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { 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"length": 1186, "header": "tr|A0A8V0YJR5-1|A0A8V0YJR5_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 2 OS=Gallus gallus OX=9031 GN=ADAMTS2 PE=4 SV=1 CANONICAL=A0A8V0YJR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5/entry", "sequence": { "sequence": 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"length": 1186, "header": "tr|A0A8V0YJR5-1|A0A8V0YJR5_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 2 OS=Gallus gallus OX=9031 GN=ADAMTS2 PE=4 SV=1 CANONICAL=A0A8V0YJR5-1" }, "locus": { "chromosome": "13", "start_pos": 13431562, "end_pos": 13265977, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036399.1", "url": "https://www.ensembl.org/id/ENSGALT00010036399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021177.1", "url": "https://www.ensembl.org/id/ENSGALP00010021177.1" } ] } }, { "isoform_ac": "A0A8V0YSV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV5/entry", "sequence": { "sequence": "MEPPAGFACVLLCCALCLPAAAPRRPGHRDPILRNIEEYSLVIPTSTDSEGRFLSHLVSGPPKARFRRAADDLQHKAANEQIFYNVTVFGREFHFRLRPNSRLVAPGATVEWQEDSDETHIEPLYGNCLYVGDITDLPNASVAISNCDGLAGMIRTDKDEFFIEPLEKGTREEEEEGGRTHVVYRRAAAKKQLPIEDADTLYKAPNLTNLDGLDSALSLIEDGVRRSRQRHRRHATDDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHAEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELNRYLHSYDCLRDDPFEHDWPSLPQLPGIHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPENPYFCKTKKGPPLDGTMCAPGKHCFKGHCIWLTPDILKQDGHWGAWSKFGSCSRTCGTGVKYRTRQCDNPHPANGGRTCVGPSYEFQLCNTQDCPKDFEDFREEQCRQWDPYFEYQNTKHHWLPYEHVDAKERCHLYCESKETGDVVYMKRMVHDGTRCSYKDAYSICVRGECLKVGCDRVIGSTKQEDKCGVCGGDNSHCKVVKGTFSRVPKKQGHIKMFEIPVGARHLLIQESDATSHHLAIKNRETGRFILSEDNYVPDSKVFIDMGVEWEYRNDDNRETVQTMGPLRNGIVILVIPHGGAKISLTYKYMIHEDSLNVDNNNVLEEDSVSYEWALKKWSQCSRPCGGGFQFTKYGCRRKTDHKMVHRSYCELIQKPKPIRRVCNLQECSQPIWVTGEWEPCSKSCGKTGYQVRSVRCIQPLHDNTNRSVHTKYCNNDRPEGRRPCNRELCPAQWRIGPWSQCSVSCGNGTQDRPVLCRTSDNAIGLCKEAKPENVKICRLPPCPKDHCQGDKSMFCRMEVLSRYCSIPGYNKLCCKSCNMYNNVTEEGNATDSNANKNNVIEEELLTTPSPLTGVPTTQPATTSPPPVSKPPMPPSNATDEHPEINAVDVPYKIDGLDNEVSQHNIITQRRVPYERTRNQRIQELIAEKRKKETLRRIN", "length": 1157, "header": "tr|A0A8V0YSV5-1|A0A8V0YJR5_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 2 OS=Gallus gallus OX=9031 GN=ADAMTS2 PE=4 SV=1 CANONICAL=A0A8V0YJR5-1" }, "locus": { "chromosome": "13", "start_pos": 13431562, "end_pos": 13265977, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036396.1", "url": "https://www.ensembl.org/id/ENSGALT00010036396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021175.1", "url": "https://www.ensembl.org/id/ENSGALP00010021175.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1070, "end_pos": 1072, "annotation": 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Isoform 1 of Alpha-crystallin A chain OS=Gallus gallus OX=9031 GN=CRYAA PE=3 SV=1 CANONICAL=A0A8V0YJR9-1" }, "locus": { "chromosome": "1", "start_pos": 109853084, "end_pos": 109850290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028419.1", "url": "https://www.ensembl.org/id/ENSGALT00010028419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016297.1", "url": "https://www.ensembl.org/id/ENSGALP00010016297.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRRGGMEQGGRRAFGSICPNRAPGPPARGAKKPARTGGAAAGTPPAGLTRGPVLPAAPVGPAAPPQVTRGPARLRRCESFAAVGADPAPSPGFIRAQGPCLQDEPEFDFQDLRDAVDYFISDASAWVPPPPDCSDFDFSLGEDVAFGTCAVCPQPPESLQPCWRDAAEQHRQALGDALEENSQLQEALAQKQEELATLRESNVQLKELASQARQLAAVLDKLMLPQRPDGADLPPPSPHPPPAGSCGRAEAAGVGGMLRAVSAQCRAALRSLAGGPDAKRPRFHGAFRGLRTARAAVPRSPGGAEPEGGGSLRAALGEQGGIRTLAFPQGNAFTLRTAGGGYRFRWVPR", "length": 349, "header": "tr|A0A8V0YJW3-1|A0A8V0YJW3_CHICK Isoform 1 of Multicilin OS=Gallus gallus OX=9031 GN=MCIDAS PE=3 SV=1 CANONICAL=A0A8V0YJW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3/entry", "sequence": { "sequence": "GRRGGMEQGGRRAFGSICPNRAPGPPARGAKKPARTGGAAAGTPPAGLTRGPVLPAAPVGPAAPPQVTRGPARLRRCESFAAVGADPAPSPGFIRAQGPCLQDEPEFDFQDLRDAVDYFISDASAWVPPPPDCSDFDFSLGEDVAFGTCAVCPQPPESLQPCWRDAAEQHRQALGDALEENSQLQEALAQKQEELATLRESNVQLKELASQARQLAAVLDKLMLPQRPDGADLPPPSPHPPPAGSCGRAEAAGVGGMLRAVSAQCRAALRSLAGGPDAKRPRFHGAFRGLRTARAAVPRSPGGAEPEGGGSLRAALGEQGGIRTLAFPQGNAFTLRTAGGGYRFRWVPR", "length": 349, "header": "tr|A0A8V0YJW3-1|A0A8V0YJW3_CHICK Isoform 1 of Multicilin OS=Gallus gallus OX=9031 GN=MCIDAS PE=3 SV=1 CANONICAL=A0A8V0YJW3-1" }, "locus": { "chromosome": "Z", "start_pos": 17272084, "end_pos": 17270431, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032312.1", "url": "https://www.ensembl.org/id/ENSGALT00010032312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019102.1", "url": "https://www.ensembl.org/id/ENSGALP00010019102.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJW5-1", "uniprot_ac": "A0A8V0YJW5", "uniprot_id": "A0A8V0YJW5_CHICK", "mass": { "chemical_mass": 112465.0, "monoisotopic_mass": 112465.0 }, "refseq": { "ac": "NP_989653", "name": "glycine dehydrogenase (decarboxylating), mitochondrial precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" }, "gene_names": [ { "name": "GLDC", "type": "recommended", "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ] }, { "name": "GDC", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "GLDC", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "P-protein", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] } ], "protein_names": [ { "name": "Glycine cleavage system P protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5/entry#names_and_taxonomy" } ] }, { "name": "1.4.4.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5/entry#names_and_taxonomy" } ] }, { "name": "glycine cleavage system P protein", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine decarboxylase, glycine cleavage system protein P)", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine dehydrogenase (aminomethyl-transferring)", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine dehydrogenase (decarboxylating), mitochondrial precursor", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine dehydrogenase (decarboxylating), mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine dehydrogenase (decarboxylating", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "name": "glycine dehydrogenase [decarboxylating], mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_989653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.7291.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000090.1. On Sep 23, 2021 this sequence version replaced NP_989653.2.", "evidence": [ { "database": "RefSeq", "id": "NP_989653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ] }, { "annotation": "Regions required for chicken glycine decarboxylase gene transcription were examined.", "evidence": [ { "database": "RefSeq", "id": "NP_989653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" }, { "database": "PubMed", "id": "19084582", "url": "https://glygen.org/publication/PubMed/19084582" } ] }, { "annotation": "The glycine cleavage system catalyzes the degradation of glycine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5#function" }, { "database": "UniProtKB", "id": "RU364056", "url": "https://www.uniprot.org/uniprotkb/RU364056#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLDC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5", "locus": { "chromosome": "Z", "start_pos": 28445965, "end_pos": 28483985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012973", "url": "https://www.ensembl.org/id/ENSGALG00010012973" } ] } } ], "crossref": [ { "id": "A0A8V0YJW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00613", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00613", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374222", "url": "https://www.ncbi.nlm.nih.gov/gene/374222", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374222", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374222", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNLICTC", "url": "https://omabrowser.org/oma/group/RNLICTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJW5", "url": "https://www.orthodb.org/?gene=A0A8V0YJW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11773:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11773:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21478", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21478", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783984", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783984", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24304", "url": "https://www.rhea-db.org/rhea/24304", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSCGRWWGRLAARGAPRHLRPAAGGPRRQQQRWGGGEAARCIEQLLPRHDDFCRRHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVGENEILETLYNIASKNKIWRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTMVCDITGMDVANASLLDEGTAAAEAMQLCHRQNKRRKFYIDARCHPQTIAVVQTRANYTGVITELKLPHEMDFSGKDVSGVLFQYPDTEGKVEDFSELIERAHQNGTLACCATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKENLVRMMPGRMVGVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIARRVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIYSDGRLGVSLDETVNEKDLDDILWIFGCESSAELVAEGMGEETKGILSTPFKRTSKFLTHQVFNSYHSETNIVRYMKRLENKDISLVHSMIPLGSCTMKLNSSAELAPISWKEFANIHPFVPLDQAQGYQQLFKDLEKDLCEITGYDKISFQPNSGAQGEYAGLAAIKAYLNAKGERHRSVCLIPRSAHGTNPASAQMAGMKIQPIEVDKNGSIDISHLKAMVDKHKENLAAIMITYPSTNGVFEEEIGDVCDLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPYLPTHPVIKIQTDKDACPLGTVSAAPWGSSAILPISWVYIKTMGAKGLKHASEIAILNANYMAKRLEKHYKILFRGVRGYVAHEFILDTRPFKKTANIEAVDLAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKGELDRFCDAMISIRQEIADIEEGRMDPQVNPLKMSPHTLNCVTSSKWDRPYSREVAAFPLPFVKPESKFWPTIARIDDIYGDQHLVCTCPPMEAYESPFSEQKRASS", "length": 1010, "header": "tr|A0A8V0YJW5-1|A0A8V0YJW5_CHICK Isoform 1 of Glycine cleavage system P protein OS=Gallus gallus OX=9031 GN=GLDC PE=1 SV=1 CANONICAL=A0A8V0YJW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5/entry", "sequence": { "sequence": "MQSCGRWWGRLAARGAPRHLRPAAGGPRRQQQRWGGGEAARCIEQLLPRHDDFCRRHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVGENEILETLYNIASKNKIWRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTMVCDITGMDVANASLLDEGTAAAEAMQLCHRQNKRRKFYIDARCHPQTIAVVQTRANYTGVITELKLPHEMDFSGKDVSGVLFQYPDTEGKVEDFSELIERAHQNGTLACCATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKENLVRMMPGRMVGVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIARRVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIYSDGRLGVSLDETVNEKDLDDILWIFGCESSAELVAEGMGEETKGILSTPFKRTSKFLTHQVFNSYHSETNIVRYMKRLENKDISLVHSMIPLGSCTMKLNSSAELAPISWKEFANIHPFVPLDQAQGYQQLFKDLEKDLCEITGYDKISFQPNSGAQGEYAGLAAIKAYLNAKGERHRSVCLIPRSAHGTNPASAQMAGMKIQPIEVDKNGSIDISHLKAMVDKHKENLAAIMITYPSTNGVFEEEIGDVCDLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPYLPTHPVIKIQTDKDACPLGTVSAAPWGSSAILPISWVYIKTMGAKGLKHASEIAILNANYMAKRLEKHYKILFRGVRGYVAHEFILDTRPFKKTANIEAVDLAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKGELDRFCDAMISIRQEIADIEEGRMDPQVNPLKMSPHTLNCVTSSKWDRPYSREVAAFPLPFVKPESKFWPTIARIDDIYGDQHLVCTCPPMEAYESPFSEQKRASS", "length": 1010, "header": "tr|A0A8V0YJW5-1|A0A8V0YJW5_CHICK Isoform 1 of Glycine cleavage system P protein OS=Gallus gallus OX=9031 GN=GLDC PE=1 SV=1 CANONICAL=A0A8V0YJW5-1" }, "locus": { "chromosome": "Z", "start_pos": 28483965, "end_pos": 28446455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031132.1", "url": "https://www.ensembl.org/id/ENSGALT00010031132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018126.1", "url": "https://www.ensembl.org/id/ENSGALP00010018126.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Genomic organization of regions that regulate chicken glycine decarboxylase gene transcription: physiological and pathological implications.", "journal": "Gene", "date": "2009-03-01", "authors": "Kawaguchi Hiroshi, Okamoto Soshi, Sikdar Dwaipayan, Kume Akihiro, Li Fang, Mohafez Omar Mahmoud Mohamed, Shehata Mohammed Hassan, Hiraga Koichi", "evidence": [ { "database": "RefSeq", "id": "NP_989653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989653" } ], "reference": [ { "type": "PubMed", "id": "19084582", "url": "https://glygen.org/publication/PubMed/19084582" } ] } ], "pathway": [ { "id": "gga:374222", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374222", "resource": "KEGG Pathway" }, { "id": "R-GGA-6783984", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783984", "resource": "Reactome", "description": "Glycine degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BJQ1-1", "protein_name": "Glycine cleavage system P protein", "gene_name": "GLDC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQTCARAWGLRLGCGVGGGRRLAGGAGPRWAPRGRDRSSGGGDSGGAGASRLLERLLPRHDDFARRHIGPGDKDQKEMLQALGLASVDELIEKTIPASIRLKRPLKMDDPVCENEILATLHAISNKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEATAAAEAMQLCHRQNKRRKFFVDPRCHPQTIAVVQTRAKYSGVLIELKLPHEMDFSSKDVSGVLFQYPDTEGKVEDFTELVERAHEAGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRENLVRMMPGRMVGVTRDVSGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAVMFAIYHGSHGLEHIARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINIRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEERRGILGTAFKRTSPFLTHQVFNSYHSETNIVRYMKRLENKDISLVHSMIPLGSCTMKLNSSSELTPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDRISFQPNSGAQGEYAGLASIRAYLDAKGETHRTVCLIPKSAHGTNPASAHMAGMRIQPVEVDKYGNIDAAHLKAMVDKHKENLAAIMITYPSTNGVFEENIGDVCDLIHLHGGQVYLDGANMNAQVGLCRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLVPFLPNHPIISLKPSEDAQALGTVSAAPWGSSCILPISWAYIKMMGGKGLKQATEIAILNANYMAKRLEKHYRVLFRGARGYVAHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFVKPENKFWPTISRIDDIYGDQHLVCTCPPMDVYESPFSEQKRASS", "length": 1020 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23378-1", "protein_name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "gene_name": "GLDC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "length": 1020 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49095-1", "protein_name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "gene_name": "GCV2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRTRVTALLCRATVRSSTNYVSLARTRSFHSQSILLKTAATDITSTQYSRIFNPDLKNIDRPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNICTAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELINKTWFDTLTIKLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLLKVFDIENSSQFLSEDYSNSFPREFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSITGFDGISLQPNSGAQGEYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGLKVVPVNCLQDGSLDLVDLKNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFGGQVYLDGANMNAQVGLTSPGDLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPHLPKHDVVDMITGIGGSKSIDSVSSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLNSNYMMTRLKDHYKILFVNEMSTLKHCAHEFIVDLREYKAKGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMIEPTESENLEELDRFCDAMISIKEEINALVAGQPKGQILKNAPHSLEDLITSSNWDTRGYTREEAAYPLPFLRYNKFWPTVARLDDTYGDMNLICTCPSVEEIANETE", "length": 1034 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54KM7-1", "protein_name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "gene_name": "gcvP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKLLRNNGINKLKSNLIRNYSTKQSIFQALDTFPKRHIGPNENEINEMLKSINTSKLSKKNPNSLEQLIEYTIPKDIRLNRELNIEENKVIGENQLLKDLKKIAEKNKVYRSFIGMGYYGTITPHVIQRNILENPGWYTPYTPYQAEISQGRLESLLNFQTMVSEFTGLPMSNASLLDEATAAAEAMQMCVNISKSKGPFAFLVDKYCHPQTIDTIKTRAEPKGIRIEVVDSKDFKFTEDVVGCIVQYPSSNGVITDYKEMADRAHQANALVVAATDLLSLALLKPPGEWGADIALGNSQRFGVPLGFGGPHAAFFSTKDKYARLLPGRIIGVSKDKQGNSAFRMALQTREQHIRREKATSNICTSQALLANMSAMYAVYHGQQGIKDIANAVHRKAIILAEGIKRLGYTVLDRPFFDTVLIITGDKTDMMIKELESRQINVRQYCSKSISISLDETVTSADISALLNGFSAHASKPLGLSSPEQLEKETSTISVISEEFARQTPFLTHPIFNRYHSEHELLRYIHKLQKKDLGLTTAMIPLGSCTMKLNATTEMYPVSWPEFNSIHPFVPANQSLGYKEMFESISNMLCEVTGFDGCSLQPNAGSQGEYAGLMVIRSYLTSIGQSQRNVCLIPVSAHGTNPASAAMVGMKVVVVDCDTNGNIDVADLKAKAEKHKDTLAALMITYPSTHGVFEEGANDICDIIHANGGQVYMDGANMNAQVGLCRPGDIGADVCHLNLHKTFCIPHGGGGPGMGPICVKSHLAPFLPGHSVVKGVGGERAMSAVSAGPWGSSSILPITYVYLKLMGGQGLKKATQVAILNANYMASRLKDHYKILYTGSHGLVAHEFIIDLRMFKESAGIEAEDVAKRLQDMNFHGPTMSWPVPNTLMIEPTESESKYELDRLCDALILIREEIREIETGKADRKNNVLVNSPHTEKVIVADNWNYPYSRSKAAFPTPATVASKFWPTVGRIDNVHGDKNLVCSCPPLSDYQ", "length": 994 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91W43-1", "protein_name": "Glycine dehydrogenase (decarboxylating), mitochondrial", "gene_name": "Gldc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLCARAWGLRLGRGAGGGHRLARGTGLSWAQRSRDSSGGGGGGGGGDRGAAGASRLLERLLPRHDDFSRRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKMEDPICENEILETLHAIASKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRKKFFVDPRCHPQTIAVVQTRAKYRGVLVELKLPHEMDFSGKDVCGVLFQYPDTEGKVEDFTELVDRAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVKENLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSQGLKHIAKRVHNATLILSEGLKRAGHQLQHDLFFDTLKVQCGCSVKEVLGRAAQRQINFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSAELVAEGMGEERRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWREFANIHPFVPLDQAQGYQQLFQGLEKDLCEITGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDRYGNIDVAHLKAMVDQHKENLAAIMITYPSTNGVFEENIGDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLSPFLPSHPVISIKPTEGTWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLEKHYRVLFRGARGYVAHEFILDTRPFKKSANVEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSCWDRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS", "length": 1025 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94B78-1", "protein_name": "Glycine dehydrogenase (decarboxylating) 1, mitochondrial", "gene_name": "GLDP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MERARRLAYRGIVKRLVNDTKRHRNAETPHLVPHAPARYVSSLSPFISTPRSVNHTAAFGRHQQTRSISVDAVKPSDTFPRRHNSATPDEQTHMAKFCGFDHIDSLIDATVPKSIRLDSMKFSKFDAGLTESQMIQHMVDLASKNKVFKSFIGMGYYNTHVPTVILRNIMENPAWYTQYTPYQAEISQGRLESLLNFQTVITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADGFDLKVVTSDLKDIDYSSGDVCGVLVQYPGTEGEVLDYAEFVKNAHANGVKVVMATDLLALTVLKPPGEFGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYKRMMPGRIIGISVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAGLKSIAQRVHGLAGIFSLGLNKLGVAEVQELPFFDTVKIKCSDAHAIADAASKSEINLRVVDSTTITASFDETTTLDDVDKLFKVFASGKPVPFTAESLAPEVQNSIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQSKDLSLCHSMIPLGSCTMKLNATTEMMPVTWPSFTDIHPFAPVEQAQGYQEMFENLGDLLCTITGFDSFSLQPNAGAAGEYAGLMVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIITVGTDAKGNINIEEVRKAAEANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMNAQVGLTSPGFIGADVCHLNLHKTFCIPHGGGGPGMGPIGVKNHLAPFLPSHPVIPTGGIPQPEKTAPLGAISAAPWGSALILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLEKHYPVLFRGVNGTVAHEFIIDLRGFKNTAGIEPEDVAKRLMDYGFHGPTMSWPVPGTLMIEPTESESKAELDRFCDALISIREEIAQIEKGNADVQNNVLKGAPHPPSLLMADTWKKPYSREYAAFPAPWLRSSKFWPTTGRVDNVYGDRKLVCTLLPEEEQVAAAVSA", "length": 1037 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VH09-1", "protein_name": "Glycine cleavage system P protein", "gene_name": "Gldc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQRFLGRSSQSLLLRCGHRYLATTPVEEVIFPTKSDFPSRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQLKRELDLDKPLNEHELIRRIRDISLKNQLWRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQGRLESLLNYQTLVTDLTGLDVANASLLDEGTAAAEAMCLATRHNKRKKLYLSNRVHPQTLSVVKTRTEALELEIVVGPIEQADLPSRELAGILLQYPDTYGDVKDFEDIAALAKKNGTLVVVATDLLSLTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQSLVRLMPGRMIGVTRDMDGNDAYRLALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMANRIHHFTLTLQTGVLGAGHEVINKNFFDTLHIRLGGGQSLEDLKERAEHKRINLRYLEDDTVGVALDETVSVADVDDLLWVFKAEASVEHILARKDVLKNSIENSKFLRTSPYLQHPIFQSYHSESRMVRYMKKLENKDISLVHSMIPLGSCTMKLNSTTEMMPCSFRHFTDIHPFAPVEQAQGFHQMFKELEHDLCEITGYDRISFQPNSGAQGEYAGLRAIRSYHEHRNEGHRNICLIPISAHGTNPASAQMAGMKVEPIRILSNGSIDMAHLRAKAEEHAHELSCLMITYPSTMGVFEETVADICTLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPYLPGHPVVSPLSSEEHSFGVVSAAPFGSSAILPISWSYIKLMGSRGLKRATQVAILNANYMSKRLEQHYKTLYKAPNSQLVAHEFILDIRDLKKSANIEAVDVAKRLMDYGFHAPTMSWPVAGTLMIEPTESEDKEELDRFCDAMISIREEIAEIEAGRMDKAVNPLKMSPHTQAQVISDKWDRPYTREQAAFPAIFVKPDAKIWPTVGRIDDAYGDKHLVCTCPPILPDL", "length": 985 }, "evidence": [ { "id": "A0A8V0YJW5", "url": "https://omabrowser.org/oma/group/A0A8V0YJW5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" }, { "name": "glycine cleavage complex", "id": "GO:0005960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005960", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" }, { "name": "glycine dehydrogenase (decarboxylating) activity", "id": "GO:0004375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" }, { "name": "glycine binding", "id": "GO:0016594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycine decarboxylation via glycine cleavage system", "id": "GO:0019464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24304", "name": "", "equation": "N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJW5-1", "P15505-1" ], "evidence": [ { "id": "24304", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24304" } ] }, { "id": "R-GGA-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YJW5-1" ], "evidence": [ { "id": "R-GGA-5693967", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693967" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YJW5", "gene_name": "GLDC", "activity": [ { "ec_number": "1.4.4.2", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.", "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ] }, { "ec_number": "1.4.4.2", "activity": "", "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" } ] } ] }, { "uniprot_ac": "P15505", "gene_name": "GLDC", "activity": [ { "ec_number": "1.4.4.2", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.", "evidence": [ { "id": "P15505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15505" } ] }, { "ec_number": "1.4.4.2", "activity": "", "evidence": [ { "id": "P15505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15505" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" }, { "id": "PF01212", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aromatic amino acid beta-eliminating lyase/threonine aldolase", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 719, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" }, { "id": "PF02347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycine cleavage system P-protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 478, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW5" }, { "id": "PF21478", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21478" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycine dehydrogenase C-terminal", "eco_id": "ECO_0000259", "start_pos": 819, "end_pos": 940, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.4.4.2", "ec_name": "N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.", "evidence": [ { "id": "1.4.4.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.4.2" }, { "id": "1.4.4.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.4.4.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 663, "end_pos": 665 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YJY3-1", "uniprot_ac": "A0A8V0YJY3", "uniprot_id": "A0A8V0YJY3_CHICK", "mass": { "chemical_mass": 32543.0, "monoisotopic_mass": 32543.0 }, "refseq": {}, "gene_names": [ { "name": "CLIC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ] } ], "protein_names": [ { "name": "Chloride intracellular channel protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). Promotes cell-surface expression of HRH3.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3#function" }, { "database": "UniProtKB", "id": "ARBA00045955", "url": "https://www.uniprot.org/uniprotkb/ARBA00045955#function" }, { "database": "UniProtKB", "id": "A0A8V0YJY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY8#function" }, { "database": "UniProtKB", "id": "A0A8V0YT21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT21#function" }, { "database": "UniProtKB", "id": "ARBA00055840", "url": "https://www.uniprot.org/uniprotkb/ARBA00055840#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3", "locus": { "chromosome": "4", "start_pos": 1779524, "end_pos": 1784350, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015145", "url": "https://www.ensembl.org/id/ENSGALG00010015145" } ] } } ], "crossref": [ { "id": "A0A8V0YJY3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10298", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10298", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJY3", "url": "https://www.orthodb.org/?gene=A0A8V0YJY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJY8", "url": "https://www.orthodb.org/?gene=A0A8V0YJY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT21", "url": "https://www.orthodb.org/?gene=A0A8V0YT21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32751", "url": "https://www.rhea-db.org/rhea/32751", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69412", "url": "https://www.rhea-db.org/rhea/69412", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69651", "url": "https://www.rhea-db.org/rhea/69651", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKLRQESVWGGGQHGAGNNRRKSSRGGVRFPWAMVVLQLAMAIAAGVGTGGAPTSACSLPKQTPYTKEEALSAFIVILPACVSLVQHPGTASPSPAVSALWRTAVLMQQLQSFKALQLLGPLLCHPWVPRSMRCPRLTPASPSRYPHLSPKYKESFDVGSDIFAKFSAYIKNSRKEANSNLEKALLREFQRLDQYLTTPLPEEIDQDSVEDITISKRKFLDGDHLTLADCNLLPKLHIIKIAAKKYRDFEIPADMTGVWRYLNNAYACDEFSHTCPADEEIVHTYASVARKMT", "length": 294, "header": "tr|A0A8V0YJY3-1|A0A8V0YJY3_CHICK Isoform 1 of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC2 PE=1 SV=1 CANONICAL=A0A8V0YJY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3/entry", "sequence": { "sequence": "MGKLRQESVWGGGQHGAGNNRRKSSRGGVRFPWAMVVLQLAMAIAAGVGTGGAPTSACSLPKQTPYTKEEALSAFIVILPACVSLVQHPGTASPSPAVSALWRTAVLMQQLQSFKALQLLGPLLCHPWVPRSMRCPRLTPASPSRYPHLSPKYKESFDVGSDIFAKFSAYIKNSRKEANSNLEKALLREFQRLDQYLTTPLPEEIDQDSVEDITISKRKFLDGDHLTLADCNLLPKLHIIKIAAKKYRDFEIPADMTGVWRYLNNAYACDEFSHTCPADEEIVHTYASVARKMT", "length": 294, "header": "tr|A0A8V0YJY3-1|A0A8V0YJY3_CHICK Isoform 1 of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC2 PE=1 SV=1 CANONICAL=A0A8V0YJY3-1" }, "locus": { "chromosome": "4", "start_pos": 1781797, "end_pos": 1780710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036488.1", "url": "https://www.ensembl.org/id/ENSGALT00010036488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021243.1", "url": "https://www.ensembl.org/id/ENSGALP00010021243.1" } ] } }, { "isoform_ac": "A0A8V0YJY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY8/entry", "sequence": { "sequence": "MDLRHQKVGGHLPEPEPSPACKQGTPGALTPAFLPSFLCSRKPEELKDLAPGTNPPFLLFNRELKTDFIKIEEFLEQTLCPPTYPHLSPKYKESFDVGSDIFAKFSAYIKNSRKEANSNLEKALLREFQRLDQYLTTPLPEEIDQDSVEDITISKRKFLDGDHLTLADCNLLPKLHIIKIAAKKYRDFEIPADMTGVWRYLNNAYACDEFSHTCPADEEIVHTYASVARKMT", "length": 232, "header": "tr|A0A8V0YJY8-1|A0A8V0YJY8_CHICK Computationally mapped isoform of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC2 PE=1 SV=1 CANONICAL=A0A8V0YJY3-1" }, "locus": { "chromosome": "4", "start_pos": 1782080, "end_pos": 1780710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036494.1", "url": "https://www.ensembl.org/id/ENSGALT00010036494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021248.1", "url": "https://www.ensembl.org/id/ENSGALP00010021248.1" } ] } }, { "isoform_ac": "A0A8V0YT21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT21/entry", "sequence": { "sequence": "MRCPSSSTSSSSPPGFVSGQALTSLLSPQAGLDGENIGNCPFCQRLFMVLWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLLFNRELKTDFIKIEEFLEQTLCPPTYPHLSPKYKESFDVGSDIFAKFSAYIKNSRKEANSNLEKALLREFQRLDQYLTTPLPEEIDQDSVEDITISKRKFLDGDHLTLADCNLLPKLHIIKIAAKKYRDFEIPADMTGVWRYLNNAYACDEFSHTCPADEEIVHTYASVARKMT", "length": 257, "header": "tr|A0A8V0YT21-1|A0A8V0YJY3_CHICK Computationally mapped isoform of Chloride intracellular channel protein OS=Gallus gallus OX=9031 GN=CLIC2 PE=1 SV=1 CANONICAL=A0A8V0YJY3-1" }, "locus": { "chromosome": "4", "start_pos": 1782332, "end_pos": 1780710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036491.1", "url": "https://www.ensembl.org/id/ENSGALT00010036491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021246.1", "url": "https://www.ensembl.org/id/ENSGALP00010021246.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": 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} ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-189398", "name": "HMOX1 dimer, HMOX2 cleave heme", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-71185" ], "output_participant_list": [ "R-ALL-189385", "R-ALL-189396" ], "enzyme_list": [ "A0A8V0YXK7-1", "A0A8V0YK13-1" ], "evidence": [ { "id": "R-GGA-189398", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189398" } ] }, { "id": "R-GGA-9609921", "name": "SGTA binds Tail-anchored protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPW4-1", "A0A8V0YK13-1" ], "evidence": [ { "id": "R-GGA-9609921", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9609921" } ] }, { "id": "R-GGA-9708457", "name": "HM13 cleaves HMOX1 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YK13-1" ], "evidence": [ { "id": "R-GGA-9708457", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9708457" } ] }, { "id": "R-GGA-9708536", "name": "HMOX1 translocates from the cytosol to the nucleoplasm", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [ "R-GGA-9609901" ], "output_participant_list": [ "R-GGA-9708567" ], "enzyme_list": [ "A0A8V0YK13-1" ], "evidence": [ { "id": "R-GGA-9708536", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9708536" } ] }, { "id": "R-GGA-9708558", "name": "HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"https://www.reactome.org/PathwayBrowser/#R-GGA-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001378842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YK22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVYSIFRSGHLLVLLCLFTVEGKKSPTGKHTCRKGLLSQVTENLYTKASSLKSSVPKDLIKNTRLLKKTTKMLFMTNCNVRDQLLSFYMKNVFSHLGMESEKLFVISAFRVLQENMNACLPCAPSTRLTSAVKNIKKTFLKLGEKGVYKAINELDILLPWIQAYIQTIV", "length": 170, "header": "tr|A0A8V0YK22-1|A0A8V0YK22_CHICK Isoform 1 of Interleukin family protein OS=Gallus gallus OX=9031 GN=IL26 PE=3 SV=1 CANONICAL=A0A8V0YK22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK22/entry", "sequence": { "sequence": "MKVYSIFRSGHLLVLLCLFTVEGKKSPTGKHTCRKGLLSQVTENLYTKASSLKSSVPKDLIKNTRLLKKTTKMLFMTNCNVRDQLLSFYMKNVFSHLGMESEKLFVISAFRVLQENMNACLPCAPSTRLTSAVKNIKKTFLKLGEKGVYKAINELDILLPWIQAYIQTIV", "length": 170, "header": "tr|A0A8V0YK22-1|A0A8V0YK22_CHICK Isoform 1 of Interleukin family protein OS=Gallus gallus OX=9031 GN=IL26 PE=3 SV=1 CANONICAL=A0A8V0YK22-1" }, "locus": { "chromosome": "1", "start_pos": 35215340, "end_pos": 35208727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028572.1", "url": "https://www.ensembl.org/id/ENSGALT00010028572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016409.1", "url": "https://www.ensembl.org/id/ENSGALP00010016409.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The novel chicken interleukin 26 protein is overexpressed in T cells and induces proinflammatory cytokines.", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77" } ] }, { "name": "RNF170", "type": "synonym", "evidence": [ { "id": "XP_015135911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135911" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF170", "type": "recommended", "evidence": [ { "id": "A0A8V0YK77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YK77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF170 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135911" } ] }, { "name": "RING finger protein 170", "type": "synonym", "evidence": [ { "id": "A0A8V0YK77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase RNF170", "type": "synonym", "evidence": [ { "id": "A0A8V0YK77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135911" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF170", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK77", "locus": { "chromosome": "Z", "start_pos": 54356893, "end_pos": 54381172, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011971", "url": "https://www.ensembl.org/id/ENSGALG00010011971" } ] } } ], "crossref": [ { "id": "A0A8V0YK77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK77", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CRQEEQN", "url": "https://omabrowser.org/oma/group/CRQEEQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK77", "url": "https://www.orthodb.org/?gene=A0A8V0YK77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22894:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22894:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METESRKNTDTKEMEKLTQLEALLLTAVLENCVDQLAILGYIMPVSHEGKTDISHINSQKTKEITGTQNVLDIKYQELTSARQGSGETVTSKSLKSTEHKQQLGNPEDPKRAHHLSKRATKPSALSADYLRKIQADRQYTSDVITATMKKMEESGTFDSLIEANGKEKAKNSNLNDILIREEEGKKEIKSLQKQLQDVKKETEIELQNRDNVILYLKNELQGMEAKAAMEQRYMKKSADLQVHQAQKKCSNAENRLNKEIEDLKRKTDEEIRVHMEIENFLRHYYKKVEEKLEYWADKHENDTDAKDKEINALKESRAENLEMLQRFASECRTFEETIIADRAQKEAERRKREQDAMELKSILKLQAWWRGTMVRRNLGPYQNLRKAQEKQLLNQKSKKEKPAAKKKTR", "length": 409, "header": "tr|A0A8V0YKG2-1|A0A8V0YKG2_CHICK Isoform 1 of Dynein regulatory complex protein 9 OS=Gallus gallus OX=9031 GN=IQCG PE=3 SV=1 CANONICAL=A0A8V0YKG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2/entry", "sequence": { "sequence": "METESRKNTDTKEMEKLTQLEALLLTAVLENCVDQLAILGYIMPVSHEGKTDISHINSQKTKEITGTQNVLDIKYQELTSARQGSGETVTSKSLKSTEHKQQLGNPEDPKRAHHLSKRATKPSALSADYLRKIQADRQYTSDVITATMKKMEESGTFDSLIEANGKEKAKNSNLNDILIREEEGKKEIKSLQKQLQDVKKETEIELQNRDNVILYLKNELQGMEAKAAMEQRYMKKSADLQVHQAQKKCSNAENRLNKEIEDLKRKTDEEIRVHMEIENFLRHYYKKVEEKLEYWADKHENDTDAKDKEINALKESRAENLEMLQRFASECRTFEETIIADRAQKEAERRKREQDAMELKSILKLQAWWRGTMVRRNLGPYQNLRKAQEKQLLNQKSKKEKPAAKKKTR", "length": 409, "header": "tr|A0A8V0YKG2-1|A0A8V0YKG2_CHICK Isoform 1 of Dynein regulatory complex protein 9 OS=Gallus gallus OX=9031 GN=IQCG PE=3 SV=1 CANONICAL=A0A8V0YKG2-1" }, "locus": { "chromosome": "9", "start_pos": 14820418, "end_pos": 14802350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036743.1", "url": "https://www.ensembl.org/id/ENSGALT00010036743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021427.1", "url": "https://www.ensembl.org/id/ENSGALP00010021427.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG2" }, { "id": "PF27661", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27661" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRC9/10 N-terminal", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 163, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 301, "end_pos": 303 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKI2-1", "uniprot_ac": "A0A8V0YKI2", "uniprot_id": "A0A8V0YKI2_CHICK", "mass": { "chemical_mass": 43227.0, "monoisotopic_mass": 43227.0 }, "refseq": { "ac": "XP_001231675", "name": "snRNA-activating protein complex subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231675" }, "gene_names": [ { "name": "SNAPC3", "type": "recommended", "evidence": [ { "id": "A0A8V0YKI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2" } ] }, { "name": "SNAPC3", "type": "synonym", "evidence": [ { "id": "XP_001231675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231675" } ] } ], "protein_names": [ { "name": "snRNA-activating protein complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YKI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2/entry#names_and_taxonomy" } ] }, { "name": "Small nuclear RNA-activating complex polypeptide 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YKI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex subunit 3", "type": "synonym", "evidence": [ { "id": "XP_001231675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231675" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231675.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231675" } ] }, { "annotation": "Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2#function" }, { "database": "UniProtKB", "id": "ARBA00025193", "url": "https://www.uniprot.org/uniprotkb/ARBA00025193#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNAPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2", "locus": { "chromosome": "1", "start_pos": 45296953, "end_pos": 45293453, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013558", "url": "https://www.ensembl.org/id/ENSGALG00010013558" } ] } } ], "crossref": [ { "id": "A0A8V0YKI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "768769", "url": "https://www.ncbi.nlm.nih.gov/gene/768769", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768769", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768769", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHRDDCL", "url": "https://omabrowser.org/oma/group/AHRDDCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKI2", "url": "https://www.orthodb.org/?gene=A0A8V0YKI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13421:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13421:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001231675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEAVEYEAGETHTRVFRVGALGSGWQQCLQPRDLSLAEEEEEEEAAGAVAEELGCTAETAAELRALCSVDTLVSADQERDPEAIPEDSGLETLRFRKKALQRREERIVVDRACRQETLTYEMESHAIGKRPDDAADLVEEGELLLTLNVFYPVIFQKHKEHKPYQTVLVLGSQRLTELRDSLSCVSDLQIGGEFSSEPDRAPEHISKDIYKSAFFYFEGIFYNDSRYPECRDLSRTIIEWSESRDRGYGNLQSVKMEDYTFNDLSLRIGYPYLFCHQGDCEHIVIVTDIRLIHHEDCLDRNLYPLLIKKHWLCTRKCFVCKMYTARWVTNKDSLAPEDPCFFCDVCFRMLHYDAEGNKLGDFLAYPYVDPGIFN", "length": 376, "header": "tr|A0A8V0YKI2-1|A0A8V0YKI2_CHICK Isoform 1 of snRNA-activating protein complex subunit 3 OS=Gallus gallus OX=9031 GN=SNAPC3 PE=3 SV=1 CANONICAL=A0A8V0YKI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI2/entry", "sequence": { "sequence": "MAAEAVEYEAGETHTRVFRVGALGSGWQQCLQPRDLSLAEEEEEEEAAGAVAEELGCTAETAAELRALCSVDTLVSADQERDPEAIPEDSGLETLRFRKKALQRREERIVVDRACRQETLTYEMESHAIGKRPDDAADLVEEGELLLTLNVFYPVIFQKHKEHKPYQTVLVLGSQRLTELRDSLSCVSDLQIGGEFSSEPDRAPEHISKDIYKSAFFYFEGIFYNDSRYPECRDLSRTIIEWSESRDRGYGNLQSVKMEDYTFNDLSLRIGYPYLFCHQGDCEHIVIVTDIRLIHHEDCLDRNLYPLLIKKHWLCTRKCFVCKMYTARWVTNKDSLAPEDPCFFCDVCFRMLHYDAEGNKLGDFLAYPYVDPGIFN", "length": 376, "header": "tr|A0A8V0YKI2-1|A0A8V0YKI2_CHICK Isoform 1 of snRNA-activating protein complex subunit 3 OS=Gallus gallus OX=9031 GN=SNAPC3 PE=3 SV=1 CANONICAL=A0A8V0YKI2-1" }, "locus": { "chromosome": "1", "start_pos": 45294639, "end_pos": 45293512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032608.1", "url": "https://www.ensembl.org/id/ENSGALT00010032608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019323.1", "url": "https://www.ensembl.org/id/ENSGALP00010019323.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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} ] }, { "name": "IFN-lambda3", "type": "synonym", "evidence": [ { "id": "NP_001121968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" } ] }, { "name": "Interferon lambda 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YKJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ0/entry#names_and_taxonomy" } ] }, { "name": "interferon lambda-3 A", "type": "synonym", "evidence": [ { "id": "NP_001121968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" } ] }, { "name": "interferon lambda-3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001121968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" } ] }, { "name": "interleukin 28B (interferon, lambda 3)", "type": "synonym", "evidence": [ { "id": "NP_001121968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" } ] }, { "name": "interleukin 28", "type": "synonym", "evidence": 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The reference sequence was derived from EU399904.1. On Jun 17, 2008 this sequence version replaced XP_001234104.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" } ] }, { "annotation": "Analysis of IL28B alleles with virologic response patterns and plasma cytokine levels in HIV/HCV-coinfected patients.", "evidence": [ { "database": "RefSeq", "id": "NP_001121968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121968" }, { "database": "PubMed", "id": "23135173", "url": "https://glygen.org/publication/PubMed/23135173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFNL3A", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKJ7-1", "uniprot_ac": "A0A8V0YKJ7", "uniprot_id": "A0A8V0YKJ7_CHICK", "mass": { "chemical_mass": 45272.0, "monoisotopic_mass": 45272.0 }, "refseq": {}, "gene_names": [ { "name": "BCAT1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ] } ], "protein_names": [ { "name": "Branched-chain-amino-acid aminotransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.42", "type": "synonym", "evidence": [ { "id": "A0A8V0YKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7#function" }, { "database": "UniProtKB", "id": "ARBA00057137", "url": "https://www.uniprot.org/uniprotkb/ARBA00057137#function" }, { "database": "UniProtKB", "id": "A0A8V0YRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW7#function" }, { "database": "UniProtKB", "id": "A0A8V0YYN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN7#function" }, { "database": "UniProtKB", "id": "A0A8V0YYP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7", "locus": { "chromosome": "1", "start_pos": 65478746, "end_pos": 65418649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015306", "url": "https://www.ensembl.org/id/ENSGALG00010015306" } ] } } ], "crossref": [ { "id": "A0A8V0YKJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418193", "url": "https://www.ncbi.nlm.nih.gov/gene/418193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YKJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRW7", "url": "https://www.orthodb.org/?gene=A0A8V0YRW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYN7", "url": "https://www.orthodb.org/?gene=A0A8V0YYN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYP2", "url": "https://www.orthodb.org/?gene=A0A8V0YYP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11825", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11825", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11825:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11825:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "18321", "url": "https://www.rhea-db.org/rhea/18321", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24801", "url": "https://www.rhea-db.org/rhea/24801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24813", "url": "https://www.rhea-db.org/rhea/24813", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGCQNKCMAGGCSEEATKYVTESFKASDLIITPATTLKEKPDPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATETRGQTEENLVPMLWLNEYALFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGENELATPPLDGIILPGVTRQSILDLARNWGEFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPQLTTQILNKLTDIQYGREDSDWTVLVS", "length": 405, "header": "tr|A0A8V0YKJ7-1|A0A8V0YKJ7_CHICK Isoform 1 of Branched-chain-amino-acid aminotransferase OS=Gallus gallus OX=9031 GN=BCAT1 PE=1 SV=1 CANONICAL=A0A8V0YKJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7/entry", "sequence": { "sequence": "MKGCQNKCMAGGCSEEATKYVTESFKASDLIITPATTLKEKPDPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATETRGQTEENLVPMLWLNEYALFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGENELATPPLDGIILPGVTRQSILDLARNWGEFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPQLTTQILNKLTDIQYGREDSDWTVLVS", "length": 405, "header": "tr|A0A8V0YKJ7-1|A0A8V0YKJ7_CHICK Isoform 1 of Branched-chain-amino-acid aminotransferase OS=Gallus gallus OX=9031 GN=BCAT1 PE=1 SV=1 CANONICAL=A0A8V0YKJ7-1" }, "locus": { "chromosome": "1", "start_pos": 65476252, "end_pos": 65418775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036840.1", "url": "https://www.ensembl.org/id/ENSGALT00010036840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021462.1", "url": "https://www.ensembl.org/id/ENSGALP00010021462.1" } ] } }, { "isoform_ac": "A0A8V0YRW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW7/entry", "sequence": { "sequence": "MINGRTVKFNVRGLSEQMHGWRMFRGSNKASDLIITPATTLKEKPDPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGENELATPPLDGIILPGVTRQSILDLARNWGEFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPQLTTQILNKLTDIQYGREDSDWTVLVS", "length": 389, "header": "tr|A0A8V0YRW7-1|A0A8V0YKJ7_CHICK Computationally mapped isoform of Branched-chain-amino-acid aminotransferase OS=Gallus gallus OX=9031 GN=BCAT1 PE=1 SV=1 CANONICAL=A0A8V0YKJ7-1" }, "locus": { "chromosome": "1", "start_pos": 65476252, "end_pos": 65438100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036816.1", "url": "https://www.ensembl.org/id/ENSGALT00010036816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021449.1", "url": "https://www.ensembl.org/id/ENSGALP00010021449.1" } ] } }, { "isoform_ac": "A0A8V0YYN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN7/entry", "sequence": { "sequence": "MAYFIATSTHSHQNTGCQNKCMAGGCSEEATKYVTESFKASDLIITPATTLKEKPDPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGENELATPPLDGIILPGVTRQSILDLARNWGEFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPQLTTQILNKLTDIQYGREDSDWTVLVS", "length": 399, "header": "tr|A0A8V0YYN7-1|A0A8V0YKJ7_CHICK Computationally mapped isoform of Branched-chain-amino-acid aminotransferase OS=Gallus gallus OX=9031 GN=BCAT1 PE=1 SV=1 CANONICAL=A0A8V0YKJ7-1" }, "locus": { "chromosome": "1", "start_pos": 65476252, "end_pos": 65436431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036825.1", "url": "https://www.ensembl.org/id/ENSGALT00010036825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021453.1", "url": "https://www.ensembl.org/id/ENSGALP00010021453.1" } ] } }, { "isoform_ac": "A0A8V0YYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP2/entry", "sequence": { "sequence": "MKASDLIITPATTLKEKPDPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGENELATPPLDGIILPGVTRQSILDLARNWGEFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPQLTTQILNKLTDIQYGREDSDWTVLVS", "length": 362, "header": "tr|A0A8V0YYP2-1|A0A8V0YKJ7_CHICK Computationally mapped isoform of Branched-chain-amino-acid aminotransferase OS=Gallus gallus OX=9031 GN=BCAT1 PE=1 SV=1 CANONICAL=A0A8V0YKJ7-1" }, "locus": { "chromosome": "1", "start_pos": 65476252, "end_pos": 65418775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036831.1", "url": "https://www.ensembl.org/id/ENSGALT00010036831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021458.1", "url": "https://www.ensembl.org/id/ENSGALP00010021458.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "L-leucine biosynthetic process", "id": "GO:0009098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "L-valine biosynthetic process", "id": "GO:0009099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "amino acid biosynthetic process", "id": "GO:0008652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" }, { "name": "branched-chain amino acid biosynthetic process", "id": "GO:0009082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "branched-chain-amino-acid transaminase activity", "id": "GO:0004084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004084", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18321", "name": "", "equation": "L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKJ7-1" ], "evidence": [ { "id": "18321", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18321" } ] }, { "id": "24801", "name": "", "equation": "L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKJ7-1" ], "evidence": [ { "id": "24801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24801" } ] }, { "id": "24813", "name": "", "equation": "L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKJ7-1" ], "evidence": [ { "id": "24813", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24813" } ] }, { "id": "R-GGA-508189", "name": "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKJ7-1" ], "evidence": [ { "id": "R-GGA-508189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-508189" } ] }, { "id": "R-GGA-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKJ7-1" ], "evidence": [ { "id": "R-GGA-70723", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70723" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKJ7", "gene_name": "BCAT1", "activity": [ { "ec_number": "2.6.1.42", "activity": "L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.", "evidence": [ { "id": "A0A8V0YKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ] }, { "ec_number": "2.6.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.6.1.42", "ec_name": "L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.", "evidence": [ { "id": "2.6.1.42", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.42" }, { "id": "2.6.1.42", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.42" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKK3-1", "uniprot_ac": "A0A8V0YKK3", "uniprot_id": "A0A8V0YKK3_CHICK", "mass": { "chemical_mass": 158721.0, "monoisotopic_mass": 158721.0 }, "refseq": { "ac": "XP_015133285", "name": "mitogen-activated protein kinase kinase kinase kinase 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133285" }, "gene_names": [ { "name": "MAP4K4", "type": "recommended", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "name": "MAP4K4", "type": "synonym", "evidence": [ { "id": "XP_015133285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133285" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase kinase kinase kinase 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015133285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133285" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015133285.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133285" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP4K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3", "locus": { "chromosome": "1", "start_pos": 133835512, "end_pos": 133686357, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013582", "url": "https://www.ensembl.org/id/ENSGALG00010013582" } ] } } ], "crossref": [ { "id": "cd06636", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06636", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418714", "url": "https://www.ncbi.nlm.nih.gov/gene/418714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418714", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEKRNGW", "url": "https://omabrowser.org/oma/group/LEKRNGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKK3", "url": "https://www.orthodb.org/?gene=A0A8V0YKK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKM1", "url": "https://www.orthodb.org/?gene=A0A8V0YKM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL77", "url": "https://www.orthodb.org/?gene=A0A8V0YL77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN27", "url": "https://www.orthodb.org/?gene=A0A8V0YN27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN41", "url": "https://www.orthodb.org/?gene=A0A8V0YN41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015133285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVQWSHLASLKSNVSPVSRSHSFSDPSPKFAHHHLRSQDPYPPSRSEVLNQSSDSKSEVPDPTQKAWARSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQSTVDKKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTTNETQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1386, "header": "tr|A0A8V0YKK3-1|A0A8V0YKK3_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3/entry", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVQWSHLASLKSNVSPVSRSHSFSDPSPKFAHHHLRSQDPYPPSRSEVLNQSSDSKSEVPDPTQKAWARSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQSTVDKKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTTNETQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1386, "header": "tr|A0A8V0YKK3-1|A0A8V0YKK3_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "locus": { "chromosome": "1", "start_pos": 133834767, "end_pos": 133686596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032644.1", "url": "https://www.ensembl.org/id/ENSGALT00010032644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019344.1", "url": "https://www.ensembl.org/id/ENSGALP00010019344.1" } ] } }, { "isoform_ac": "A0A8V0YKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM1/entry", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVQWSHLASLKSNVSPVSRSHSFSDPSPKFAHHHLRSQDPYPPSRSEVLNQSSDSKSEVPDPTQKAWARSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQSTVDKKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTTNETQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1354, "header": "tr|A0A8V0YKM1-1|A0A8V0YKM1_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "locus": { "chromosome": "1", "start_pos": 133834767, "end_pos": 133686596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032670.1", "url": "https://www.ensembl.org/id/ENSGALT00010032670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019360.1", "url": "https://www.ensembl.org/id/ENSGALP00010019360.1" } ] } }, { "isoform_ac": "A0A8V0YL77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL77/entry", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQSTVDKKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTTNETQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1309, "header": "tr|A0A8V0YL77-1|A0A8V0YL77_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "locus": { "chromosome": "1", "start_pos": 133834767, "end_pos": 133686596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032648.1", "url": "https://www.ensembl.org/id/ENSGALT00010032648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019347.1", "url": "https://www.ensembl.org/id/ENSGALP00010019347.1" } ] } }, { "isoform_ac": "A0A8V0YN27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN27/entry", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVQWSHLASLKSNVSPVSRSHSFSDPSPKFAHHHLRSQDPYPPSRSEVLNQSSDSKSEVPDPTQKAWARSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQSTVDKKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTTNETQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1357, "header": "tr|A0A8V0YN27-1|A0A8V0YN27_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "locus": { "chromosome": "1", "start_pos": 133834767, "end_pos": 133686596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032657.1", "url": "https://www.ensembl.org/id/ENSGALT00010032657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019353.1", "url": "https://www.ensembl.org/id/ENSGALP00010019353.1" } ] } }, { "isoform_ac": "A0A8V0YN41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN41/entry", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEEMERRRKEEEERRRAEEEKRRVEREQEYRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRQQQQQQQQQQQQQQQQERNKQSYHTPEPKSHYEPAERAREVEERFRKTNQGSPEAQSKQMGKVLEPPVPSRSESFSNGNSEPAQPALQRPMEPQVQWSHLASLKSNVSPVSRSHSFSDPSPKFAHHHLRSQDPYPPSRSEVLNQSSDSKSEVPDPTQKAWARSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNNQAGQRNSTSNIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRMRSSSKSEGSPSQRHESAPKKPEEKKEVFRPIKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDMEQEGADESTSGPDDVRAVSTLNLSNGETESVKTMIVHDDVESEPALTPSKEGTLIVRQTQSASNTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSSEAMRTEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQSSIQPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1293, "header": "tr|A0A8V0YN41-1|A0A8V0YN41_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=MAP4K4 PE=1 SV=1 CANONICAL=A0A8V0YKK3-1" }, "locus": { "chromosome": "1", "start_pos": 133834767, "end_pos": 133686596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032683.1", "url": "https://www.ensembl.org/id/ENSGALT00010032683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019369.1", "url": "https://www.ensembl.org/id/ENSGALP00010019369.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 970, "start_aa": "Thr", "end_pos": 970, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr970", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 972, "start_aa": "Thr", "end_pos": 972, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr972", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418714", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M754-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Map4k4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEDEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHAQQPPPPQQQDRSKPSYHAPEPKPHYDPADRAREVEDRFRKTNHSSPEAQAKQTGRGLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVPEPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAAKKPEDKKEVFRPLKPAVRIDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCTIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1318 }, "evidence": [ { "id": "A0A8V0YKK3", "url": "https://omabrowser.org/oma/group/A0A8V0YKK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95819-1", "protein_name": "Mitogen-activated protein kinase kinase kinase kinase 4", "gene_name": "MAP4K4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "length": 1239 }, "evidence": [ { "id": "A0A8V0YKK3", "url": "https://omabrowser.org/oma/group/A0A8V0YKK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97820-1", "protein_name": "Mitogen-activated protein kinase kinase kinase kinase 4", "gene_name": "Map4k4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTVTAAIKVMDVTEDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGGPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLHDHRRPHAQQQPPPPQQQDRSKPSFHAPEPKPHYDPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVPEPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGGGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSPRQESAAKKPDDKKEVFRSLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSPNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELLHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCGRNDKVFFSSVRSGGSSQVYFMTLGRTSLLSW", "length": 1233 }, "evidence": [ { "id": "A0A8V0YKK3", "url": "https://omabrowser.org/oma/group/A0A8V0YKK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W002-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "msn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSRRGDESNLLRDWDFDRFFPKNANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRPVPRGYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAHKRQDSDSRLPTNFERGFRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQRNSIYSSSISSKSKENDVPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRREKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW", "length": 1504 }, "evidence": [ { "id": "A0A8V0YKK3", "url": "https://omabrowser.org/oma/group/A0A8V0YKK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", 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"A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", 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"A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKK9-1", "uniprot_ac": "A0A8V0YKK9", "uniprot_id": "A0A8V0YKK9_CHICK", "mass": { "chemical_mass": 87719.0, "monoisotopic_mass": 87719.0 }, "refseq": { "ac": "XP_004949393", "name": "sulfate anion transporter 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949393" }, "gene_names": [ { "name": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949393.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949393" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC26A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9", "locus": { "chromosome": "Z", "start_pos": 54261054, "end_pos": 54225415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013587", "url": "https://www.ensembl.org/id/ENSGALG00010013587" } ] } } ], "crossref": [ { "id": "A0A8V0YKK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748788", "url": "https://www.ncbi.nlm.nih.gov/gene/101748788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748788", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748788", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNENQDL", "url": "https://omabrowser.org/oma/group/WNENQDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKK9", "url": "https://www.orthodb.org/?gene=A0A8V0YKK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT13", "url": "https://www.orthodb.org/?gene=A0A8V0YT13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-174362", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174362", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-427601", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-427601", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004949393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "72275", "url": "https://www.rhea-db.org/rhea/72275", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72379", "url": "https://www.rhea-db.org/rhea/72379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75091", "url": "https://www.rhea-db.org/rhea/75091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75095", "url": "https://www.rhea-db.org/rhea/75095", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75335", "url": "https://www.rhea-db.org/rhea/75335", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75339", "url": "https://www.rhea-db.org/rhea/75339", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLYADRINKREQRLCKLTEKPLFNSSSGTAFSKESCAPEELCYCALIRNLLWIYCSCFVPLEKIHEVKARTMERPLEATKMENSTSCFFMERKAHVKARRKEIVLAKLRKSFSCTPRKLKNFVMDFLPVLRWLPKYQCKEYIWGDVMSGLVIGIILVPQAIAYSLLAGLKPIYSLYTSFFANIIYFLMGTSRHVSVGIFSLISLMVGQVVDRELLLAGFDLNDDVTPALGPGSLQTDSQFNTTVFNLTTEGMNAECGKECYAIGIATALTFVAGVYQVLMGVFRLGFVSMYLSESVLDGFATGASLTILTAQVKYLIGIKIPRSQGHGMLVITWINIFRNISQANICDIITSSICIVVLVTAKELGDRYKHKLKFPLPTELVVIVVATLVSHYGNLNEVYSSSVSGAIPTGFIAPKVPRFDLMIRVAIDALPLAVVSFVFTVSLSEMCAKKYAYTIRANQEMFAVGFCNIIPSFFHSFATSAALAKTLVKTSTGCQTQVSGVISAMVVLLVLLFLAPLFYSLQKCVLACIIIVSLRGALRKFRDVPARYHVNKVDTVVWVVTMFASALISTEIGLLVGIVFSMLCIIVRTQQPRTALLGQIPDTNFYEDDLEYENLSSVPKVKIFRFEAPLYYANRNYFLKSLYRLTDLDPNLEAARRKKYEKKERQQLKEGNQPTVNGLGSRDTTLQLVPKQIDFQALIVDCSSIPFLDTTGVNTLKEILKDYKELNISVLLACCNPSVIDSLKRGGYFGKDFGSMQEMLFYSIHNAVRFAKDQKLTADSSV", "length": 785, "header": "tr|A0A8V0YKK9-1|A0A8V0YKK9_CHICK Isoform 1 of Sulfate transporter OS=Gallus gallus OX=9031 GN=SLC26A1 PE=3 SV=1 CANONICAL=A0A8V0YKK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9/entry", "sequence": { "sequence": "MKRLYADRINKREQRLCKLTEKPLFNSSSGTAFSKESCAPEELCYCALIRNLLWIYCSCFVPLEKIHEVKARTMERPLEATKMENSTSCFFMERKAHVKARRKEIVLAKLRKSFSCTPRKLKNFVMDFLPVLRWLPKYQCKEYIWGDVMSGLVIGIILVPQAIAYSLLAGLKPIYSLYTSFFANIIYFLMGTSRHVSVGIFSLISLMVGQVVDRELLLAGFDLNDDVTPALGPGSLQTDSQFNTTVFNLTTEGMNAECGKECYAIGIATALTFVAGVYQVLMGVFRLGFVSMYLSESVLDGFATGASLTILTAQVKYLIGIKIPRSQGHGMLVITWINIFRNISQANICDIITSSICIVVLVTAKELGDRYKHKLKFPLPTELVVIVVATLVSHYGNLNEVYSSSVSGAIPTGFIAPKVPRFDLMIRVAIDALPLAVVSFVFTVSLSEMCAKKYAYTIRANQEMFAVGFCNIIPSFFHSFATSAALAKTLVKTSTGCQTQVSGVISAMVVLLVLLFLAPLFYSLQKCVLACIIIVSLRGALRKFRDVPARYHVNKVDTVVWVVTMFASALISTEIGLLVGIVFSMLCIIVRTQQPRTALLGQIPDTNFYEDDLEYENLSSVPKVKIFRFEAPLYYANRNYFLKSLYRLTDLDPNLEAARRKKYEKKERQQLKEGNQPTVNGLGSRDTTLQLVPKQIDFQALIVDCSSIPFLDTTGVNTLKEILKDYKELNISVLLACCNPSVIDSLKRGGYFGKDFGSMQEMLFYSIHNAVRFAKDQKLTADSSV", "length": 785, "header": "tr|A0A8V0YKK9-1|A0A8V0YKK9_CHICK Isoform 1 of Sulfate transporter OS=Gallus gallus OX=9031 GN=SLC26A1 PE=3 SV=1 CANONICAL=A0A8V0YKK9-1" }, "locus": { "chromosome": "Z", "start_pos": 54258605, "end_pos": 54225528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032650.1", "url": "https://www.ensembl.org/id/ENSGALT00010032650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019349.1", "url": "https://www.ensembl.org/id/ENSGALP00010019349.1" } ] } }, { "isoform_ac": "A0A8V0YT13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT13/entry", "sequence": { "sequence": "MQIDQSQTDDFSFIPTCKNRAEHFCQKVIQEKIHEVKARTMERPLEATKMENSTSCFFMERKAHVKARRKEIVLAKLRKSFSCTPRKLKNFVMDFLPVLRWLPKYQCKEYIWGDVMSGLVIGIILVPQAIAYSLLAGLKPIYSLYTSFFANIIYFLMGTSRHVSVGIFSLISLMVGQVVDRELLLAGFDLNDDVTPALGPGSLQTDSQFNTTVFNLTTEGMNAECGKECYAIGIATALTFVAGVYQVLMGVFRLGFVSMYLSESVLDGFATGASLTILTAQVKYLIGIKIPRSQGHGMLVITWINIFRNISQANICDIITSSICIVVLVTAKELGDRYKHKLKFPLPTELVVIVVATLVSHYGNLNEVYSSSVSGAIPTGFIAPKVPRFDLMIRVAIDALPLAVVSFVFTVSLSEMCAKKYAYTIRANQEMFAVGFCNIIPSFFHSFATSAALAKTLVKTSTGCQTQVSGVISAMVVLLVLLFLAPLFYSLQKCVLACIIIVSLRGALRKFRDVPARYHVNKVDTVVWVVTMFASALISTEIGLLVGIVFSMLCIIVRTQQPRTALLGQIPDTNFYEDDLEYENLSSVPKVKIFRFEAPLYYANRNYFLKSLYRLTDLDPNLEAARRKKYEKKERQQLKEGNQPTVNGLGSRDTTLQLVPKQIDFQALIVDCSSIPFLDTTGVNTLKEILKDYKELNISVLLACCNPSVIDSLKRGGYFGKDFGSMQEMLFYSIHNAVRFAKDQKLTADSSV", "length": 752, "header": "tr|A0A8V0YT13-1|A0A8V0YKK9_CHICK Computationally mapped isoform of Sulfate transporter OS=Gallus gallus OX=9031 GN=SLC26A1 PE=3 SV=1 CANONICAL=A0A8V0YKK9-1" }, "locus": { "chromosome": "Z", "start_pos": 54258605, "end_pos": 54249301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032646.1", "url": "https://www.ensembl.org/id/ENSGALT00010032646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019346.1", "url": "https://www.ensembl.org/id/ENSGALP00010019346.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101748788", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748788", "resource": "KEGG Pathway" }, { "id": "R-GGA-174362", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174362", "resource": "Reactome", "description": "Transport and metabolism of PAPS" }, { "id": "R-GGA-427601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-427601", "resource": "Reactome", "description": "Inorganic anion exchange by SLC26 transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATM3-1", "protein_name": "Solute carrier family 26 member 1", "gene_name": "SLC26A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEESPECAPQGRGPVLVRRRPPERPGLREALKARLRRGCTCSVQGAWALLQGLFPAMHWLRRYRAREDLAGDVMSGLLIGIILVPQAIAYSLLAGLQPVYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLQAGFDPAQDGPGPEANSSAPNASATTLALGLQDCGRDCYAIRVATALTLVAGIYQVLMGILRLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVQVPRHQGPGLVISTWLSLLRGAGQANLCDLLTSAVCLTVLLAAKELSDRCRHRLKVPLPAELLVIVVATLASHFGRFHQRFGSSVAGDIPTGFVAPRVPDLGLMWRVAPDAVSLALVGSAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCRTQVSSVVSAAVVLLVLLALAPLFRDLQRSVLACIIVVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLLSTEAGLLAGVLLSLLSLAGRTQRPRAALLARVADSSFYEDTAEFEGLVPEPGVQVFRFAGPLYYANKDFFLQSLYRLTGLDAGRAASRGRERGPGGQGGRGEPVESRDLGPVSSAAALVPTATCFHAVVVDCAPLLFLDATGLATLQDLRRDYGALGISLLLACCSPSVTDTLRRGGFLGEEPGDAAEEGQLFHSVHSAVLAARACHGEPAATDSTL", "length": 706 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M3ATV7-1", "protein_name": "Sulfate transporter", "gene_name": "slc26a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGASSLEAMEEDLNCVAVGLLKRRVRQKRGVREIIKTKIQRNLSCTGPKIKSTLTGFFPVVKWLPKYKVKEYIWGDVMSGLIIGIILIPQAIAYCLLAGLEPIYGLYTSFFSNIIYFFMGTSRHVSVGIFSLMSLMVGQVVDREVFLAGFDLNEDSTKNAFGFNDTGETNITAVNLKIMSLNMECGKECYAISIATALTFLAGVYQVLMAFLRLGFVSVYLSSPMLDGFATGASCTILSVQAKYLLGLKIPRHQGYGTVVVTWINIFKNIHKTNFCDLITSAICIIVLLAGKEIQDRYKKILKIPLPTELVVVAVATIVSHFADLNGQFSSSISGAIPTGFIPPKMPSIELMPRIAWDAIPLAVISFAFTVSLSEMFAKKHGYTVRPNQEMIAIGFCNIIPSFFHSFTTSAALAKTMVKDSAGCQTQVSSIVSALVVLLVLLFFAPFFYALQKCVLACIIIVSLRGALRKFRDVPKQWRQSKIEAIVWLVTMSSTALISVELGLVIGVIFSMICVVVQTQNPKVSLLGQIEQTNDYEDMEEYDNLSPVPNVKIFRFQAPLFYANKDFFLKSLYKATKLEPFLELTRRRKLEKKARAKGQKMTDGVDQTNGDVGICLISKDVGFHTIILDCSCISMIDTTAVSTFKTVSKDYKEVGVNVILACCNTTVIDSLRKGSFFGADDIDMDRLLFHTIHSAVCFANSTTQPVNDSSV", "length": 711 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BDR3-1", "protein_name": "Solute carrier family 26 member 1", "gene_name": "SLC26A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEASPEYTEWGGQLVLVRWRPPPPPGLGEVLKAGLRRSCACSLQGTWAQLQALFPAVHWLRQYRPREALVGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELLLAGFDPAQDGLGPGANRSSLNGSAAALVLGLQDCARDCYAIRVATALTLVAGLYQVLMGILGLGFVSAYLSQPLLDGFAMGASVTILTSQLRHLLGVRVPRHQGPGLVVSTWLSLLRSAGQANLCDVLTSAVCLAVLLAAKELSDRFRHRLRVPLPAELLVIVVATIVSHLGQFHERFGSSVAGDIPTGFMAPRVPDAGLMWRVALDAASLALVGSAFSISLAEMFARSHGYAVRANQELLAVGCCNVLPAFFHCFATSAALAKSLVKTATGCHTQLSSVVSAAVVLMVLLVLAPLFRDLQRSVLACVILVSLRGALRKVRDVPRLWRLSPADALVWVATAATCVLVSTEAGLLAGVLFSLLSLAGRTRHPRTALLARAGGSSFYGDPAEFEGLAPEPGVQVFRFTGPLYYANKDFFLQSLYSLTGLDVGYAIARRKERGPGEGAGEGDPVGGRDPGSGSGGASLVPAVTRFHAVVIDCAPLLFLDVAGLATLQELHRDYGALGISLLLACCNPSVTDTLRRGGFLGEDQGDVAEDGQLFPSVHCAVQAARARHQELAASNSIL", "length": 706 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P45380-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "Slc26a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASPEPPQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPVIRWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPGNNDSTLNNTATLTVGLQDCGRDCHAIRIATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHLLGVRIPRHQGLGMVIHTWLSLLQNVGQANLCDVVTSAVCLAVLLTAKELSDRYRHYLKVPVPTELLVIVVATIASHFGQLHTRFGSSVAGNIPTGFVAPQIPDPKIMWSVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSIEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYSLTGLDAGYSATRKDRGTEVGVSNRSLVDRKDLGSVSSGDGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRKNYRALDITLLLACCSPSVRDTLRKGGFLGEDQGTAEELLFPSVHSAVETACARREELMAADSAL", "length": 703 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58735-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "Slc26a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASPEPQQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPAIHWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQANICDVVTSALCLGVLLAAKELSDRYRHRLKVPIPTELFVIVVATIVSHFGQLHTRFDSRVAGNIPTGFVAPQVPDPKIMWRVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSTEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYRLTGLDAGHSATRKDQGPEVGVSNRSLVDGKDLGSVSSGAGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRRDYRALDITLLLACCSPSVRDTLRKGGFLGEEQGAENELLFPSVHSAVEAACARREELLAADSAL", "length": 704 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2B4-1", "protein_name": "Sulfate anion transporter 1", "gene_name": "SLC26A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL", "length": 701 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LW86-1", "protein_name": "Probable sulfate transporter 3.4", "gene_name": "SULTR3;4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGHGTNRVEDMASPNNGTAGETVVEIHSVCLPPKKTAFQKLKKRVGDVFFPDDPLQRFRNQTWRNRVILGLQSLFPIFTWGSQYDLKLLRSDVISGLTIASLAIPQGISYAKLANLPPIVGLYSSFVPPLIYAVLGSSRHLAVGPVSIASLVMGSMLSESVSPTQDSILYLKLAFTSTFFAGVFQASLGLLRLGFMIDFLSKATLIGFTAGAAVIVSLQQLKGLLGIVHFTGKMQIVPVMSSVFNHRSEWSWETIVMGIGFLSILLTTRHISMRKPKLFWISAASPLASVIISTLLVYLIRSKTHAISFIGHLPKGLNPPSLNMLYFSGAHLALAIKTGIITGILSLTEGIAVGRTFASLKNYQVNGNKEMMAIGFMNMAGSCTSCYVTTGSFSRSAVNYNAGAKTAVSNIVMASAVLVTLLFLMPLFYYTPNVILAAIILTAVIGLIDYQAAYKLWKVDKFDFFTCLCSFFGVLFVSVPLGLAIAVAVSVIKILLHVTRPNTSEFGNIPGTQIYQSLGRYREASRIPGFLILAIESPIYFANSTYLQDRILRWAREEENRIKENNGTTLKCIILDMTAVSAIDTSGLEAVFELRRRLEKQSLQLVLVNPVGTVMEKLHKSKIIEALGLSGLYLTVGEAVADLSSTWKANGQP", "length": 653 }, "evidence": [ { "id": "A0A8V0YKK9", "url": "https://omabrowser.org/oma/group/A0A8V0YKK9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "oxalate transmembrane transporter activity", "id": "GO:0019531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" }, { "name": "secondary active sulfate transmembrane transporter activity", "id": "GO:0008271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" }, { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" }, { "name": "chloride:bicarbonate antiporter activity", "id": "GO:0140900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "72275", "name": "", "equation": "oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72275" } ] }, { "id": "72379", "name": "", "equation": "iodide(in) + chloride(out) = iodide(out) + chloride(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72379" } ] }, { "id": "75091", "name": "", "equation": "sulfate(out) + 2 chloride(in) = sulfate(in) + 2 chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75091" } ] }, { "id": "75095", "name": "", "equation": "oxalate(out) + 2 chloride(in) = oxalate(in) + 2 chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75095", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75095" } ] }, { "id": "75335", "name": "", "equation": "bromide(in) + chloride(out) = bromide(out) + chloride(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75335", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75335" } ] }, { "id": "75339", "name": "", "equation": "nitrate(in) + chloride(out) = nitrate(out) + chloride(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75339", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75339" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK9" }, { "id": "PS50801", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50801" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STAS", "eco_id": "ECO_0000259", "start_pos": 614, "end_pos": 774, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKR1-1", "uniprot_ac": "A0A8V0YKR1", "uniprot_id": "A0A8V0YKR1_CHICK", "mass": { "chemical_mass": 159603.0, "monoisotopic_mass": 159603.0 }, "refseq": { "ac": "XP_015140973", "name": "phospholipid-transporting ATPase VD isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140973" }, "gene_names": [ { "name": "ATP10D", "type": "recommended", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ] }, { "name": "ATP10D", "type": "synonym", "evidence": [ { "id": "XP_015140973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140973" } ] } ], "protein_names": [ { "name": "Phospholipid-transporting ATPase", "type": "recommended", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1/entry#names_and_taxonomy" } ] }, { "name": "phospholipid-transporting ATPase VD isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140973" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140973.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140973" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP10D", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1", "locus": { "chromosome": "4", "start_pos": 66282327, "end_pos": 66319390, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013459", "url": "https://www.ensembl.org/id/ENSGALG00010013459" } ] } } ], "crossref": [ { "id": "cd02073", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02073", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422768", "url": "https://www.ncbi.nlm.nih.gov/gene/422768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KKYIDCC", "url": "https://omabrowser.org/oma/group/KKYIDCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKR1", "url": "https://www.orthodb.org/?gene=A0A8V0YKR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24092:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24092:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015140973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66036", "url": "https://www.rhea-db.org/rhea/66036", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPIHWTRYRWRQLMSTEGREGGSSSNSSNKCHQATKTIGKHRIVIPCLGRFKEEYEKVSKLYMNNKIRTTKYTLLTFIPRNLFEQFHRVANLYFLFLVVLNWVPLVEAFQKEITMLPLIAVLTITALKDGLEDYSKYKMDKQINNLLTKVYSRKEKKYIDEHWKNVNVGDFIRLSCNEIIPADMVLLYSSDLDGICYIETAGLDGETNLKQRQVVRGYSEQVSEIDPEKFSGRIECESPNDDLNHFRGFVENSSKDRVGLSKENLLLRGCTVRNTEAVVGIVVYAGHETKAMLNNSGPHYKRSKLERKVNSDILWCVLLLILMCLTGAIGHGIWISRYSEIPFFNIPEPDGKSISSMLAGFNMFWTMIILLQVLIPISLYVSIEIVKLGQIYLIQNDIDFYHEKTDSTIRCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCSIAGQEYCHEENAKRLESYQERDLKDEDSADSLGHMSKWSRHDCGAENESLNRKSSNLLSGSSSDAPCSGHVAFSSRIETDVVPDTQLLEKFRHISSLSYQESEDVISKLALETMYITDFFLALAICNTVVVSIPNQPRQKMRRSSLGRMPIKSLEEIRQMFQRLSVRRLSSSPLPSIKESSSENPSSFVSKLSIFKMKLASPALDGAVQSAARPHNPDSPENPQLPEESYTVNVTAGHETHSAESPIEWSPLPKLCYEAESPDEAALVHAAKAYKCILQSRTPDQVTVDFSGLGSLTFQLLHILPFDSVRKRMSVVVRHPVSNQVVVYTKGADSVMMDLLETASEDTKNSEMQQKNIKERTQKHLDDYARKGLRTLCIAKKVMSDEEYTEWLNNHFLAETSIDNREELLLESAIRLETKLTLLGATGIEDRLQDGVPDTIQALRKAGIKIWMLTGDKRETAVNIAYACKLLEPDDRIFTLKSQSRDACALVMNNILECMQKSTPDQKKGNQKLENVPASPSTQAHGFSAGLVIDGRTLEHVLQDSLQNAFLELTKKCRAVVCCQATPLQKSVLVRLVRNKLKAMTLAVGDGANDVSMIQVADTGVGIMGQEGMQAVMASDFAISQFRHLRKLLLVHGHWCYTRLTNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWILIFFNLLFTSVPPIIYGVLDKDVSAEILMQIPQLYVMSQKSVAYLPSTFWITLLDAFYQSLACFFVPYFTYCGSDIDIFSFGNPINTAALFIILFHLLIECKSVTWIHTVVITGSILFYFIFALAFGATYRTHNPLSNPYRIMEKHMADPVFYLVCLLTTCVALLPRYFLRALQGTLFPSSVLRAKCLDKLVPEEKREAIKKWKNECFVSCRMELQVTSGSSSSATGTVLKEESVVSVLPASKIPFHACSRDDLMKEEPGNRNNLNSEKTAFLNSKRTDSVI", "length": 1410, "header": "tr|A0A8V0YKR1-1|A0A8V0YKR1_CHICK Isoform 1 of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP10D PE=3 SV=1 CANONICAL=A0A8V0YKR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1/entry", "sequence": { "sequence": "MADPIHWTRYRWRQLMSTEGREGGSSSNSSNKCHQATKTIGKHRIVIPCLGRFKEEYEKVSKLYMNNKIRTTKYTLLTFIPRNLFEQFHRVANLYFLFLVVLNWVPLVEAFQKEITMLPLIAVLTITALKDGLEDYSKYKMDKQINNLLTKVYSRKEKKYIDEHWKNVNVGDFIRLSCNEIIPADMVLLYSSDLDGICYIETAGLDGETNLKQRQVVRGYSEQVSEIDPEKFSGRIECESPNDDLNHFRGFVENSSKDRVGLSKENLLLRGCTVRNTEAVVGIVVYAGHETKAMLNNSGPHYKRSKLERKVNSDILWCVLLLILMCLTGAIGHGIWISRYSEIPFFNIPEPDGKSISSMLAGFNMFWTMIILLQVLIPISLYVSIEIVKLGQIYLIQNDIDFYHEKTDSTIRCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCSIAGQEYCHEENAKRLESYQERDLKDEDSADSLGHMSKWSRHDCGAENESLNRKSSNLLSGSSSDAPCSGHVAFSSRIETDVVPDTQLLEKFRHISSLSYQESEDVISKLALETMYITDFFLALAICNTVVVSIPNQPRQKMRRSSLGRMPIKSLEEIRQMFQRLSVRRLSSSPLPSIKESSSENPSSFVSKLSIFKMKLASPALDGAVQSAARPHNPDSPENPQLPEESYTVNVTAGHETHSAESPIEWSPLPKLCYEAESPDEAALVHAAKAYKCILQSRTPDQVTVDFSGLGSLTFQLLHILPFDSVRKRMSVVVRHPVSNQVVVYTKGADSVMMDLLETASEDTKNSEMQQKNIKERTQKHLDDYARKGLRTLCIAKKVMSDEEYTEWLNNHFLAETSIDNREELLLESAIRLETKLTLLGATGIEDRLQDGVPDTIQALRKAGIKIWMLTGDKRETAVNIAYACKLLEPDDRIFTLKSQSRDACALVMNNILECMQKSTPDQKKGNQKLENVPASPSTQAHGFSAGLVIDGRTLEHVLQDSLQNAFLELTKKCRAVVCCQATPLQKSVLVRLVRNKLKAMTLAVGDGANDVSMIQVADTGVGIMGQEGMQAVMASDFAISQFRHLRKLLLVHGHWCYTRLTNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWILIFFNLLFTSVPPIIYGVLDKDVSAEILMQIPQLYVMSQKSVAYLPSTFWITLLDAFYQSLACFFVPYFTYCGSDIDIFSFGNPINTAALFIILFHLLIECKSVTWIHTVVITGSILFYFIFALAFGATYRTHNPLSNPYRIMEKHMADPVFYLVCLLTTCVALLPRYFLRALQGTLFPSSVLRAKCLDKLVPEEKREAIKKWKNECFVSCRMELQVTSGSSSSATGTVLKEESVVSVLPASKIPFHACSRDDLMKEEPGNRNNLNSEKTAFLNSKRTDSVI", "length": 1410, "header": "tr|A0A8V0YKR1-1|A0A8V0YKR1_CHICK Isoform 1 of Phospholipid-transporting ATPase OS=Gallus gallus OX=9031 GN=ATP10D PE=3 SV=1 CANONICAL=A0A8V0YKR1-1" }, "locus": { "chromosome": "4", "start_pos": 66311879, "end_pos": 66282503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032404.1", "url": "https://www.ensembl.org/id/ENSGALT00010032404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019171.1", "url": "https://www.ensembl.org/id/ENSGALP00010019171.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 682, "start_aa": "Thr", "end_pos": 682, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr682", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M6H4-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP10D", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQPGSHRILDMTELLQWARYHWQRPIGRTNTDDDERPYSYSSLLACGGKSSQTPRLAGKHRVVVPHLQLFKEEYEKFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRVANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLVTKVYSRKEKKYVDRCWKDVTVGDFIHLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQKQVVRRYAEQDSEVDPEKFSSRIECESPNNDLNRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVMGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLVVMCLTGALGHGIWLSRYENIPFFNIPEPDGHSLSPVLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQVYFIQSDVDFYNEKMGSTVQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAASEDEDSADTPSGSLSNMAKPRALSCRTVHSRPLGSISSNHLTGSCFALESREGASEVPHSRQAAFSSPIETDVVPDTRLLDKFSQITPLLFTPTDETIPDPPLETLYIIDFFIALAICNTVVVSAPNQPRQKVGLSSLRGIPIKSLEEIKNLFQRLSVRRSSSPSLASGKEPSGVPNAFVSRLSLFNRMKPASPVEEEISQTSESLQGSDDSACPTEIEKQNSDAGIANGKVEALPGQPLTSSLCYEAESPDEAALVYAARAYQCTLQSRTPEQVVVDFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSAIMELLSVASPDGPGLEKQQMMIREKTQKHLDDYAKRGLRTLCIAKRVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPEAIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPNDKLFVLNTESKNACEMLMDTILKELQKNPASPEQASLSASLHQPPPTLQGSGLRAALIITGKTLEFALQESLQKQFLELTARCQAVVCCRATPLQKSEVVKLVRSHLRVMTLAIGDGANDVSMIQVADIGIGISGQEGMQAVMASDFAVSQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQRSEAYLPLTFWITLLDAFYQSLVCFFVPYYTYQGSDIDIFTFGNPLNTAALFVILLHLVIESKSLTWIHMLVIAGSILCYFCFALAFGAMCVTCNPPSNPYWIMQEHMADPVFYLVCVLTTCVALLPRFIYRVLQGSLFPSPILRAKHLDRLPAEERIEALKKWRGTGQMDQLTSKYADHSAVESERIPIYDPSAVFAVMSATACAVEKGNLPVCETALDSDFSETKASGMAGPSKD", "length": 1432 }, "evidence": [ { "id": "A0A8V0YKR1", "url": "https://omabrowser.org/oma/group/A0A8V0YKR1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ACD6B6M8-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "atp10d", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERLRWVQHRCLQLISTDRRRGWYSSPSSLPPKSSQDAQDPQVQRLSGKRRVVVSRWDTHHSEYRSFSKGFQNNSIRTTKYTLISFIPMNLFQQFHRAANLYFLFLVLLNWVPAVEAFQKEITMIPLAVVLTVIAFKDAMEDYRRYRYDKKINNTLTHVYSGKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGCEFVPENFSSRIECENPNNDLRRFRGFMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNMDVLWSVALLLLMCFIAAIGHGLWLSELEDPIFMIPDNTHPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSLEQYEDQACGDVDRSLTLRSRTSKKSLSCKSLSCNRSSVSLNTLTAESDTHSVHDTLRRHTTGAFSSTMECAVVPDPQLHMKLSTLSSPMRSPLRPDAAEISLILDFFLALTVCNTVVVSSPSQPRHVVQMPVVRTPLRSLEEMKAMFQKLSLPRFPHSPNTNTDTPPSLTKKLFARGRSASYFPNSNPQTPVTPLESPVKLSGTPSDTPPALIPPALSSSGAWGEDAEDKKQAKDNAADESESDDEDEEEELLYEAESPDEAALVQAAKAYGCTLLGRSPEQVLVAVPGTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIMELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQELQLEVQQVTKADEPEGDCISDCVLVIDGRTLDYALQKELQGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIHASLLIFSGLFYYAFVLLFSITCVTCNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAFSNTICPSDLVKAQKIERLSAQDYSSSLQKWKENKATQRVSSRPVPQNLSVNADIPSLTECAAEGGAVLS", "length": 1365 }, "evidence": [ { "id": "A0A8V0YKR1", "url": "https://omabrowser.org/oma/group/A0A8V0YKR1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZN41-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp10d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTELLRWARHHWHRLMNGRTQGDDERSYNYSSLLACGGKSPQTPRPAGKHRVVIPHLQGFKDEYERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENMLFFNIPEPDGRVLSPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVEFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDTLSGSLSLGSVARPRAQSCRTAHSRLPGKPLAQLSGSTSAVGNGEGSGEVLHSRQAAFSSPIETDVVPDTRLLDKFSQITPQLFTRLDGAAQSAPLETLYIMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRRSSSPSLASGKDSTSGTPCAFVSRISFFSRTKLSPPVEDESSQMDEIPQASNSACCTESEAENSDVGLPIDSAEALDGPPPLASNLCYEAESPDEAALVYAARAYHCTLRSRTPEQVVVDFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVASSDGTNLEDQQMVIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSEDACGMLMSAILEELQKRTQVSPELASPRKNFPQPPDPQVPGRAGLVITGKTLEFALQESLQKQFLELTAWCQAVICCRATPLQKSEVVKLVRNHLHVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYQSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALLIILLHLVIESKSLTWIHMLVIVGSILSYFFFALAFGALCVTCNPPSNPYGIMQKHMLDPVFYLVCVLTTCVALLPRFVYRVLQGSVFPSPILRAKYFDRLSPEERAEALKRWRGTAKVNHVASKYASQSAAKSGRPRPGPSVAMKSATVCTIEQSTRETVLDLGYSKPGASTMTEPLAS", "length": 1417 }, "evidence": [ { "id": "A0A8V0YKR1", "url": "https://omabrowser.org/oma/group/A0A8V0YKR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q553A4-1", "protein_name": "Phospholipid-transporting ATPase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLGKLKIRRKKARPSYPIIEIRPNKTTENDVNKSKGYKSNDISTTKYTRYNFIFKNLFEQFKRITNIYFAAICVITLIPQVSPLSPVTSLLPLIFVLVVTALKEAFEDYRRYKADKASNYTQYQVYRDGSFRLIKSKHICVGDFIRIDNDQAFPSDILVLSSNLEDGICYVETSQLDGETNLKLFKAAKETNSLTQEQLLDLNANIECELPNNNLYKFKGKFTLQNDNSTFSLSEKQLMLRVSGARLRNTHFIIGIVLYCGKDTKLSLNQKNPPSKFSTIETRLGRSVIGIFCFKVVLVIIATVLSSLFEFNTARDSWYLRSDFDSLGFTIVKNFVSYFAILSFLIPMSLMVTLEVVKVSQAKYMEWDVKMSYKENKKYEKQIEQPQEELKIKNEDKTTTTTISPNGDIELSNIVAKKEKSKILNKYMSVKNSNLNDELALIKYIFSDKTGTLTENRMLFSKCSINGTCFDGAMNQQLLDEVTSKTKNEESIREFLLNMSLCHAAVSDVNEETGKITYQSQSPDEIALCDCAKINQFEFINRTSTHAQIRVMGEDKQYQLLAIMEFSSDRRRMSILLREEDENNDNNSTETTPIDDSSTTDIDGNLLTPPPQLTNLKKKGKIILYSKGADSIMMERLSEKESNSELLEQTKEHISQFSREGLRTLILAKREISQEEYSNWSQQYHEASTLIHDREAEMERLNDQIERGFELVGCTAIEDKLQDGVPETIDYLLKANIKVWIITGDKQETAINIGYSCKLLVPEIPIIIINAESTEECGTQIKRAIENFIDPETQVDKKVSMVINGESLTFVLKDHSADFLKIAAKCHSVVACRVTPLQKALIVRLVKKSTKEVCLSIGDGANDVSMIQEAHIGVGIFGNEGTQAARASDYALLRFRHLARLITVHGRYSMVRNSLCIKYSFYKNMAFFLCQFWFSIYSGWTAMTLYDSWIVTTFNILMTSVPPYFMALFEKDVNEKIIPKNPHLFKEVQDCHLFQYRSILNWLIGALYHSVVFFFGLYFFLDGSGDMVNQWGRIGGKELAGSFCATFAVLSILLKAAIEIKHWNFIVHIGIWGSVIVYLVISLVDSSIITQIPNMYWVFIYALHLLKFYVMVIIMIFIALVPDFTLKFVRRHLSPTNSNIEQEKYILNRGKNKNNIDNDEEI", "length": 1163 }, "evidence": [ { "id": "A0A8V0YKR1", "url": "https://omabrowser.org/oma/group/A0A8V0YKR1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9P241-1", "protein_name": "Phospholipid-transporting ATPase VD", "gene_name": "ATP10D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEALQWARYHWRRLIRGATRDDDSGPYNYSSLLACGRKSSQTPKLSGRHRIVVPHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDTVSGSLSNMAKPRAPSCRTVHNGPLGNKPSNHLAGSSFTLGSGEGASEVPHSRQAAFSSPIETDVVPDTRLLDKFSQITPRLFMPLDETIQNPPMETLYIIDFFIALAICNTVVVSAPNQPRQKIRHPSLGGLPIKSLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQVCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQPLACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRAKHFDRLTPEERTKALKKWRGAGKMNQVTSKYANQSAGKSGRRPMPGPSAVFAMKSASSCAIEQGNLSLCETALDQGYSETKAFEMAGPSKGKES", "length": 1426 }, "evidence": [ { "id": "A0A8V0YKR1", "url": "https://omabrowser.org/oma/group/A0A8V0YKR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "glycosylceramide flippase activity", "id": "GO:0140351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "66036", "name": "", "equation": "a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BX05-1", "A0A8V0YU83-1", "A0A8V0YKR1-1" ], "evidence": [ { "id": "66036", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66036" } ] }, { "id": "R-GGA-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR09-1", "A0A8V1AG66-1", "A0A8V1AKE5-1", "A0A1D5P8E2-1", "A0A3Q2U2N5-1", "F1NUR8-1", "A0A8V0Y7I0-1", "E1BX05-1", "A0A8V0YU83-1", "A0A8V0YUZ4-1", "A0A8V0YYJ1-1", "A0A8V0YJI3-1", "A0A8V0YKR1-1" ], "evidence": [ { "id": "R-GGA-939763", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-939763" } ] }, { "id": "R-GGA-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR09-1", "A0A8V1AG66-1", "A0A8V1AKE5-1", "A0A1D5P8E2-1", "A0A3Q2U2N5-1", "F1NUR8-1", "A0A8V0Y7I0-1", "E1BX05-1", "A0A8V0YU83-1", "A0A8V0YUZ4-1", "A0A8V0YYJ1-1", "A0A8V0YJI3-1", "A0A8V0YKR1-1" ], "evidence": [ { "id": "R-GGA-947591", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-947591" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P8E2", "gene_name": "ATP9B", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A1D5P8E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E2" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A1D5P8E2", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0Y7I0", "gene_name": "ATP8B1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0Y7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7I0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7I0" } ] } ] }, { "uniprot_ac": "A0A8V0YJI3", "gene_name": "ATP11A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI3" } ] } ] }, { "uniprot_ac": "A0A8V0YKR1", "gene_name": "ATP10D", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR1" } ] } ] }, { "uniprot_ac": "A0A8V0YU83", "gene_name": "ATP10A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU83" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU83" } ] } ] }, { "uniprot_ac": "A0A8V0YUZ4", "gene_name": "ATP11C", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKW9-1", "uniprot_ac": "A0A8V0YKW9", "uniprot_id": "A0A8V0YKW9_CHICK", "mass": { "chemical_mass": 339514.0, "monoisotopic_mass": 339514.0 }, "refseq": { "ac": "XP_025002444", "name": "E3 SUMO-protein ligase RanBP2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002444" }, "gene_names": [ { "name": "LOC776067", "type": "recommended", "evidence": [ { "id": "A0A8V0YKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9" } ] }, { "name": "LOC776067", "type": "synonym", "evidence": [ { "id": "XP_025002444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002444" } ] } ], "protein_names": [ { "name": "E3 SUMO-protein ligase RanBP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9/entry#names_and_taxonomy" } ] }, { "name": "E3 SUMO-protein ligase RanBP2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025002444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002444" } ] }, { "name": "Ran-binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025002444.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025002444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002444" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC776067", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9", "locus": {} } ], "crossref": [ { "id": "cd01926", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01926", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13177", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13177", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14684", "url": 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"MIRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIKEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKIAELLCNNDITDGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3054, "header": "tr|A0A8V0YKW9-1|A0A8V0YKW9_CHICK Isoform 1 of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW9/entry", "sequence": { "sequence": "MIRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIKEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKIAELLCNNDITDGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3054, "header": "tr|A0A8V0YKW9-1|A0A8V0YKW9_CHICK Isoform 1 of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136435228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037202.1", "url": "https://www.ensembl.org/id/ENSGALT00010037202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021595.1", "url": "https://www.ensembl.org/id/ENSGALP00010021595.1" } ] } }, { "isoform_ac": "A0A8V0YKY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY6/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKMAELLCSNDIADGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGGDGWNQLFDMIQAELCARPDNIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPEPKSKLIEGDPTGRDMLEMLACDRKSQSGHMLLNLSHGKEDFLREIVESFANKSGLFMLFESLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWHSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3028, "header": "tr|A0A8V0YKY6-1|A0A8V0YKY6_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037233.1", "url": "https://www.ensembl.org/id/ENSGALT00010037233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021611.1", "url": "https://www.ensembl.org/id/ENSGALP00010021611.1" } ] } }, { "isoform_ac": "A0A8V0YKZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ9/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKMAELLCSNDIADGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGGDGWNQLFDMIQAELCARPDNIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPEPKSKLIEGDPTGRDMLEMLACDRKSQSGHMLLNLSHGKEDFLREIVESFANKSGLFMLFESLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWHSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTCNLQLQEKCTTHDGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKETTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVILNSCDQKEYTGRSVYYWRRALLSLKTIQKHQNVPEPTDPLFKHFHSVDIQVFQVAAYEEEAHMAIAMLDAVEGKTDDALLAFEAIKNVVAYWNLAVLCQRKAEELEKDGMLPEEQEQCKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3053, "header": "tr|A0A8V0YKZ9-1|A0A8V0YKZ9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037274.1", "url": "https://www.ensembl.org/id/ENSGALT00010037274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021626.1", "url": "https://www.ensembl.org/id/ENSGALP00010021626.1" } ] } }, { "isoform_ac": "A0A8V0YSB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB1/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKMAELLCSNDIADGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGGDGWNQLFDMIQAELCARPDNIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3054, "header": "tr|A0A8V0YSB1-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037215.1", "url": "https://www.ensembl.org/id/ENSGALT00010037215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021602.1", "url": "https://www.ensembl.org/id/ENSGALP00010021602.1" } ] } }, { "isoform_ac": "A0A8V0YSK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSK2/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIKEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKIAELLCNNDITDGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3054, "header": "tr|A0A8V0YSK2-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037244.1", "url": "https://www.ensembl.org/id/ENSGALT00010037244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021615.1", "url": "https://www.ensembl.org/id/ENSGALP00010021615.1" } ] } }, { "isoform_ac": "A0A8V0YU37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU37/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKIAELLCNNDITDGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQGFNFSLFKSNPMAFWTSTSSLQPASKAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3054, "header": "tr|A0A8V0YU37-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037223.1", "url": "https://www.ensembl.org/id/ENSGALT00010037223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021608.1", "url": "https://www.ensembl.org/id/ENSGALP00010021608.1" } ] } }, { "isoform_ac": "A0A8V0YU42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU42/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKIAELLCNNDITDGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3028, "header": "tr|A0A8V0YU42-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037240.1", "url": "https://www.ensembl.org/id/ENSGALT00010037240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021614.1", "url": "https://www.ensembl.org/id/ENSGALP00010021614.1" } ] } }, { "isoform_ac": "A0A8V0YU55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU55/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKMAELLCSNDIADGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGGDGWNQLFDMIQAELCARPDNIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPEPKSKLIEGDPTGRDMLEMLACDRKSQSGHMLLNLSHGKEDFLREIVESFANKSGLFMLFESLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWHSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTCNLQLQEKCTTHDGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKETTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVILNSCDQKEYTGRSVYYWRRALLSLKTIQKHQNVPEPTDPLFKHFHSVDIQVFQVAAYEEEAHMAIAMLDAVEGKTDDALLAFEAIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3027, "header": "tr|A0A8V0YU55-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037267.1", "url": "https://www.ensembl.org/id/ENSGALT00010037267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021624.1", "url": "https://www.ensembl.org/id/ENSGALP00010021624.1" } ] } }, { "isoform_ac": "A0A8V0YZ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ31/entry", "sequence": { "sequence": "MVRRTKPEVERYVASVQAAASSPRERSLKGFLFAKLYFEIQEYELAKRYLSIYLSVQERDPKAHRFLGQVYEAQDNIEKAFGCYKRSVELNPMQKDLVLKMAELLCSNDIADGRAKYWVEKAARLFPGNPAAYRLKEQLLERKGEDGWNQLFDMIQTELYARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPIDSSLEWCSCVIKTLEEYLESVRDLEPDKNDWRAIKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDACELAALCYLKSFCIPKPKSKLIKGDPTGQDMLEMLACDRKSQSGHMLLNLSHGKEDFLKEIVESFANKSGLFTLFEGLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTSNLQLQEKFNTHYGTHQPPFLPLLLCKQYSTEKQRSWWDAVRTLMQKKTTPDSAPKLKLLVQHGLSTLRALEKHGLQPALMIHWARSLQKTGVSLNSFYDQKEYIGRSVYYWKKTLLSLKTIKKHKSIPEPTDPLFKHFHSVDIQVFQVAAYEEEAYIAFAMLDAVEGKTDDALLAFESIKNVVAYWNLAVLCQRKAEELENDDMLPEEQEEHKTYLLKRKHYLMKIIDESSSDPSVADKLPVSIETVTEMLNTVIQELGGNEEGESLASRNIAQAAHLEVKHPIPSPKKLSFSPTNTYKFSPKTLPQWAEDHKSLLQMLCQQVEALKNEMQEMKLNSSSVSVSSHRWPAESYGTDTVSDGYQRAQNLHEAPLTVATTGPSVYYSQSPAYNSQYLLRTAATNVTPTKAPVYGMNRLAPQQHIYAYQQPIHTPPLQNTSACVFPQDIYGTPLRFDAPAAGIISPRGADDYYNYGVPQASSNPPLPEPGYFTKPSVAPATLKPAESKVVEFSKAKFGQPGTAEGSKPPQPTTFKFNTNFKSNDGDFTFSSPLAATQPANGAFNSSERLLKLLTSDKPLPDERCIEQKGSNSHANGQRNVFSFCNKHSSGVSFTESAGQNAHKNLAFEKSDMFNFQEPSKQLFMTPNSDLANRSHETEGGSTHGGDEDDDGPHFDPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDAESKEWKERGIGNVKILKHKVSGKFRLLMRRDQVLKICANHYINTDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAILFKSKFEECQHTLKTLGSSADASMAQSTGTAKETTNQDVKESSGSTLGILNSVFQFSKDSVTSESDSKGSFTSTSTAPATFSFGKEAIQTYSSGGFGQSPLKKNQWECKVCLVRNEATAKNCASCQSPNPDMWETRGIPVTESAASLKASGSATQEKFGSAFAKKEGQWDCNICSVRNEPTATKCIACQNPSKTNSEVSPQQFSFKLEHVDAPKTTQSDLGTAFSLKGQWNCSVCLVQNEANDENCHSCQSPNSQSQANVPVSAVQALPAPSFGSAADASKPQKNAFAELFGKKEGQWDCNTCLVRNESSSPACVACQTPNPSSKPTSNASLFTSDLKNKSSEPVAGQLGTGFKCEFLGKSFKFGHADQGKTPAFTFQNLADAEAKPSKEGFNFSMLMPPGGFKFGIQESNKSTAKKDDPPKECTTDLKSIDEKDKNELPSSSGVRLQSQETADKDKDEFTFGQNSSSTFTFADLAKSTPSEGFQFGKKDPNFEGFSGAGEQLFSSKASKTGHKASTSADLGEKDDDVYKTEDSDDIHFEPIVQMPEKVEPFTGEEDEKVLYSQRVKLFRFDPETSQWKERGVGNLKILKNEVNGKVRILMRREQVLKVCANHWITTTMNLKQLSGSDKAWMWMASDFSDGDAKLEQLAAKFKTPEQAEEFKQKFEECQKLLLDIPLQTPHKLVDTGRTAQLIQKAEEMKSGLKDLKTFLTDDKTKIAEEENVNSACAGSTSDCVAKPHAEGTGPAVEWSNSELREEVLDDSLSSSVYASPLASSPVRKNLFRFGESTAGFNFSFKSALSPSKSPAKQNQSGTSVGTDEDSDLTQEEERDGQYFEPVVPLPDLVEVTSGEENEQVVFSHRAKLYRYDKDTNQWKERGIGDIKILQNYDSKQARIVMRRDQVLKLCANHRITPDMNMQQMKGSDRAWVWTACDFADGERKVELLAVRFKLQDVADSFKQTFDEAKQAQEKGTLITPHVSRTNTANTSPCGKNAVAVLEETTRERTDLSHGNDASDATVEALEVSSTSETPTKTVVSPPKFVFGSESVKSIFSNEKSKTFTFGNTSATGSLFGFSFNPPRKSADSISSSQKAEQKKTGVTEPPKSCSAPQDSKASSLAPAAQDGPSNFSFKILEQAEKTAEPSDNPPSDDVMIVYELTPTPEQRALAGFLKLPSTFFCYKNKPGYVSEEDDDEDYETAVKKLNGRLYPVNEKERRKWQVGTPVKQELERECVTASETKPSEEKAEEETLQLPSTSACGVSSNAEDAGPEGSQKEVKSERKKESEVTSSTDLVSTSKEDLHASSSSESTAVFVQSAASSEEADSTETAHVSQNLPGGDDKPVDLSTKKESDLECSESTQEHKPISFGFGNASGLSFADLASKNSGDFAFGSKDKNFKWANTGAAVFGVQTASKADEDEGGSDDEVVHSDDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDATQWKERGVGELKILFHTQKKYYRILMRRDQVLKVCANHVITKEMNLVPSDTSNNVLIWTATDYADGEVKVEQFAVRFKVQELANSFKRRFEECQQSLSELQKGHLSLAAVLSKDTNPVVYFNVSANDEPLGRITMELFANIVPRTAENFRALCTGEKGFGFKNTTFHRIVSDFICQGGDITNHDGTGGRSIYGEAFEDENFEVKHTGPGLLSMANRGRDTNNSQFFITLKKAEHLDFKHVVFGFVKDGMDVVKKIESFGSPKGLVNGRVVITDCGQI", "length": 3028, "header": "tr|A0A8V0YZ31-1|A0A8V0YKW9_CHICK Computationally mapped isoform of E3 SUMO-protein ligase RanBP2 OS=Gallus gallus OX=9031 GN=LOC776067 PE=1 SV=1 CANONICAL=A0A8V0YKW9-1" }, "locus": { "chromosome": "1", "start_pos": 136463599, "end_pos": 136395702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037250.1", "url": "https://www.ensembl.org/id/ENSGALT00010037250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021617.1", "url": "https://www.ensembl.org/id/ENSGALP00010021617.1" } ] } }, { "isoform_ac": "A0A8V0YZ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ38/entry", "sequence": { "sequence": 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"description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization 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"enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1144, "end_pos": 1146 }, { "start_pos": 1517, "end_pos": 1519 }, { "start_pos": 1593, "end_pos": 1595 }, { "start_pos": 1615, "end_pos": 1617 }, { "start_pos": 1625, "end_pos": 1627 }, { "start_pos": 1679, "end_pos": 1681 }, { "start_pos": 1697, "end_pos": 1699 }, { "start_pos": 1751, "end_pos": 1753 }, { "start_pos": 2078, "end_pos": 2080 }, { "start_pos": 2095, "end_pos": 2097 }, { "start_pos": 2270, "end_pos": 2272 }, { "start_pos": 2348, "end_pos": 2350 }, { "start_pos": 2411, "end_pos": 2413 }, { "start_pos": 2422, "end_pos": 2424 }, { "start_pos": 2679, "end_pos": 2681 }, { "start_pos": 2899, "end_pos": 2901 }, { "start_pos": 2940, "end_pos": 2942 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YKZ0-1", "uniprot_ac": "A0A8V0YKZ0", "uniprot_id": "A0A8V0YKZ0_CHICK", "mass": { "chemical_mass": 56267.0, "monoisotopic_mass": 56267.0 }, "refseq": {}, "gene_names": [ { "name": "CHGA", "type": "recommended", "evidence": [ { "id": "A0A8V0YKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0" } ] } ], "protein_names": [ { "name": "Chromogranin-A", "type": "recommended", "evidence": [ { "id": "A0A8V0YKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHGA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0", "locus": { "chromosome": "5", "start_pos": 44415015, "end_pos": 44404653, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015505", "url": "https://www.ensembl.org/id/ENSGALG00010015505" } ] } } ], "crossref": [ { "id": "A0A8V0YKZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010820", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010820", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423420", "url": "https://www.ncbi.nlm.nih.gov/gene/423420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KVMTCIA", "url": "https://omabrowser.org/oma/group/KVMTCIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YKZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLZ2", "url": "https://www.orthodb.org/?gene=F1NLZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10583:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10583:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6803157", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803157", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLZ2", "url": "https://www.uniprot.org/uniprotkb/F1NLZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NLZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPRLLAVLLLAVPAISLPVTNEMNKGDTKVMKCIVEVISDTLSKPDPLPISEECLETLRGDERIISILRHQNLLKELQEIAAQDAFMKPTVMEKGPITRWRAQGLPVLTSGANERTQQQKKNSGFEDELSEVLESQNDENKQRDVARQRPEEEQPTASLAELAAQKTQQKEDVREERKNSLEVRDSRLQDASPGEKDDQDEAESNEIKDAEDAQGEVALDNHVDKDLGEDEQQQRGEGEEQRRGPRNSLELEEEGEQPSKQGQGQSKEEAAEERVEQEDDGEDAPGEEDPTEAERLLDLAEEDGEAEEMQEDDGNDDALGFGKDEQSSEEEEEQPRLLRRGRHRLEDEGMQTEEDTFQSRDAKSEEMEDESSREWEDSKRWNKMDELAKQLSSKKHMEENDSGEDPDRSMKMAFRSHKYDFSSPEEDVRRSWKHHSKEDSSEGFPLVPMPEEKKDEEGSANRRTEDQELESLAAIEAELERVAHKLHELRRG", "length": 493, "header": "tr|A0A8V0YKZ0-1|A0A8V0YKZ0_CHICK Isoform 1 of Chromogranin-A OS=Gallus gallus OX=9031 GN=CHGA PE=1 SV=1 CANONICAL=A0A8V0YKZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ0/entry", "sequence": { "sequence": "MSPRLLAVLLLAVPAISLPVTNEMNKGDTKVMKCIVEVISDTLSKPDPLPISEECLETLRGDERIISILRHQNLLKELQEIAAQDAFMKPTVMEKGPITRWRAQGLPVLTSGANERTQQQKKNSGFEDELSEVLESQNDENKQRDVARQRPEEEQPTASLAELAAQKTQQKEDVREERKNSLEVRDSRLQDASPGEKDDQDEAESNEIKDAEDAQGEVALDNHVDKDLGEDEQQQRGEGEEQRRGPRNSLELEEEGEQPSKQGQGQSKEEAAEERVEQEDDGEDAPGEEDPTEAERLLDLAEEDGEAEEMQEDDGNDDALGFGKDEQSSEEEEEQPRLLRRGRHRLEDEGMQTEEDTFQSRDAKSEEMEDESSREWEDSKRWNKMDELAKQLSSKKHMEENDSGEDPDRSMKMAFRSHKYDFSSPEEDVRRSWKHHSKEDSSEGFPLVPMPEEKKDEEGSANRRTEDQELESLAAIEAELERVAHKLHELRRG", "length": 493, "header": "tr|A0A8V0YKZ0-1|A0A8V0YKZ0_CHICK Isoform 1 of Chromogranin-A OS=Gallus gallus OX=9031 GN=CHGA PE=1 SV=1 CANONICAL=A0A8V0YKZ0-1" }, "locus": { "chromosome": "5", "start_pos": 44414598, "end_pos": 44404836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037249.1", "url": "https://www.ensembl.org/id/ENSGALT00010037249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021616.1", "url": "https://www.ensembl.org/id/ENSGALP00010021616.1" } ] } }, { "isoform_ac": "F1NLZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NLZ2/entry", "sequence": { "sequence": "MSPRLLAVLLLAVPAISLPVTNEMNKGDTKVMKCIVEVISDTLSKPDPLPISEECLETLRGDERIISILRHQNLLKELQEIAAQGANERTQQQKKNSGFEDELSEVLESQNDENKQRDVARQRPEEEQPTASLAELAAQKTQQKEDVREERKNSLEVRDSRLQDASPGEKDDQDEAESNEIKDAEDAQGEVALDNHVDKDLGEDEQQQRGEGEEQRRGPRNSLELEEEGEQPSKQGQGQSKEEAAEERVEQEDDGEDAPGEEDPTEAERLLDLAEEDGEAEEMQEDDGNDDALGFGKDEQSSEEEEEQPRLLRRGRHRLEDEGMQTEEDTFQSRDAKSEEMEDESSREWEDSKRWNKMDELAKQLSSKKHMEENDSGEDPDRSMKMAFRSHKYDFSSPEEDVRRSWKHHSKEDSSEGFPLVPMPEEKKDEEGSANRRTEDQELESLAAIEAELERVAHKLHELRRG", "length": 466, "header": "tr|F1NLZ2-1|A0A8V0YKZ0_CHICK Computationally mapped isoform of Chromogranin-A OS=Gallus gallus OX=9031 GN=CHGA PE=1 SV=3 CANONICAL=A0A8V0YKZ0-1" }, "locus": { "chromosome": "5", "start_pos": 44414598, "end_pos": 44404836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037253.1", "url": "https://www.ensembl.org/id/ENSGALT00010037253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021618.1", "url": "https://www.ensembl.org/id/ENSGALP00010021618.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SD66-1", "protein_name": "Chromogranin-A", "gene_name": "CHGA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSFPGSGLYKWGARVPLLQCQSPVPRGGGQVPRRARTETLRPPSRASVAAARPERPVQLPLARVLAAPGPRPPAAPRPGFAMRSAAALALLLCAGQVIALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERSHQQKKQSSYEDELSEVLEKQNDQTELKEGTEEASSKEAAEKRGDSKEVEKNDEDADGAKPQASLEPPQASEAEDQTPGEEEAASTHPLASLPSKKRPGAQAEEDHEGPSQGPVDREKGPSAEQGPQAEREEEEEADAGEKAVPEEEGPRSEAFDPHPSLGYKEMQRGWPQAPAMDGAGKTGAEEAQPPEGKGAREHSRQEEEEETAGAPQGLFRGGKRGEPAQEEEERLSEEWENAKRWSKMDRLAKELTAEKRLQGEEEEEEEEEDPDRSMKLSFRAPAYGFRGPGLQLRRGWRPSSREDSVEAGLPLQVRSYLEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHKLQELRRG", "length": 530 }, "evidence": [ { "id": "A0A8V0YKZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HU91-1", "protein_name": "Chromogranin-A", "gene_name": "Chga", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSAVVLALLLCAGQVLALPVNSPMTKGDTKVMKCVVEVISDSLSKPSPMPVSPECLETLQGDERVLSILRHQNLLKELQDLALQGAKERAQQQPKQQEQQQPHSSFEDELSEVFESQSPEAKQGDATAETPPKEVVEKREDSDEVQQGGSEGTTEGPRPQAIPEPGQKSSVMGNSHAPGEDAAINTQMPASLPNQDDVDSQATGDSERGLGTQQQAGKAKQEEEEEVREKAEPEEIPTAESSSQPEYEAIQKDEGQSESHAVDGGGKTRASEALSPKGELELSQKEEDREDVMAGPPQGLFPGGKSQELEHQQEEEERLSREWEDKRWSRMDQLAKELTAEKRLQGEDDPDRSMKLSFRARAYGFRDPRPQLRRGWRPSSREESVETRGDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG", "length": 434 }, "evidence": [ { "id": "A0A8V0YKZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P10354-1", "protein_name": "Chromogranin-A", "gene_name": "Chga", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSSAALALLLCAGQVFALPVNSPMTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERVLSILRHQNLLKELQDLALQGAKERAQQQQQQQQQQQQQQQQQQQQHSSFEDELSEVFENQSPAAKHGDAASEAPSKDTVEKREDSDKGQQDAFEGTTEGPRPQAFPEPKQESSMMGNSQSPGEDTANNTQSPTSLPSQEHGIPQTTEGSERGPSAQQQARKAKQEEKEEEEEEKEEEEEEKEEKAIAREKAGPKEVPTAASSSHFYSGYKKIQKDDDGQSESQAVNGKTGASEAVPSEGKGELEHSQQEEDGEEAMAGPPQGLFPGGKGQELERKQQEEEEEEERLSREWEDKRWSRMDQLAKELTAEKRLEGEDDPDRSMKLSFRARAYGFRDPGPQLRRGWRPSSREDSVEARGDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG", "length": 466 }, "evidence": [ { "id": "A0A8V0YKZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10645-1", "protein_name": "Chromogranin-A", "gene_name": "CHGA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSAAVLALLLCAGQVTALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEWEDSKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLQALRRG", "length": 457 }, "evidence": [ { "id": "A0A8V0YKZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YKZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P26339-1", "protein_name": "Chromogranin-A", "gene_name": "Chga", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HKVIRQM", "url": "https://omabrowser.org/oma/group/HKVIRQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL12", "url": "https://www.orthodb.org/?gene=A0A8V0YL12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSE7", "url": "https://www.orthodb.org/?gene=A0A8V0YSE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSM3", "url": "https://www.orthodb.org/?gene=A0A8V0YSM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU65", "url": "https://www.orthodb.org/?gene=A0A8V0YU65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ54", "url": "https://www.orthodb.org/?gene=A0A8V0YZ54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13501:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13501:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRVSCTRLCSPQSLLSCSGRSFALEEQHRRVGECFSHCIPGSRRKAECVVLKVQSFGLCWSCGGQSQRWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 254, "header": "tr|A0A8V0YL12-1|A0A8V0YL12_CHICK Isoform 1 of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12/entry", "sequence": { "sequence": "GRVSCTRLCSPQSLLSCSGRSFALEEQHRRVGECFSHCIPGSRRKAECVVLKVQSFGLCWSCGGQSQRWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 254, "header": "tr|A0A8V0YL12-1|A0A8V0YL12_CHICK Isoform 1 of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "locus": { "chromosome": "13", "start_pos": 11618754, "end_pos": 11613282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037311.1", "url": "https://www.ensembl.org/id/ENSGALT00010037311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021636.1", "url": "https://www.ensembl.org/id/ENSGALP00010021636.1" } ] } }, { "isoform_ac": "A0A8V0YSE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSE7/entry", "sequence": { "sequence": "MAVSCFNSPFGTSLSSEGSAWVRGLLGWAWPERWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 219, "header": "tr|A0A8V0YSE7-1|A0A8V0YL12_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "locus": { "chromosome": "13", "start_pos": 11622078, "end_pos": 11613282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037319.1", "url": "https://www.ensembl.org/id/ENSGALT00010037319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021638.1", "url": "https://www.ensembl.org/id/ENSGALP00010021638.1" } ] } }, { "isoform_ac": "A0A8V0YSM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM3/entry", "sequence": { "sequence": "MKASKFTIFSDSPERGKERLCSTAVTVVLSCRWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 218, "header": "tr|A0A8V0YSM3-1|A0A8V0YL12_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "locus": { "chromosome": "13", "start_pos": 11617300, "end_pos": 11613282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037308.1", "url": "https://www.ensembl.org/id/ENSGALT00010037308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021635.1", "url": "https://www.ensembl.org/id/ENSGALP00010021635.1" } ] } }, { "isoform_ac": "A0A8V0YU65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU65/entry", "sequence": { "sequence": "MELSLCESGWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 195, "header": "tr|A0A8V0YU65-1|A0A8V0YL12_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "locus": { "chromosome": "13", "start_pos": 11617798, "end_pos": 11613282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037305.1", "url": "https://www.ensembl.org/id/ENSGALT00010037305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021634.1", "url": "https://www.ensembl.org/id/ENSGALP00010021634.1" } ] } }, { "isoform_ac": "A0A8V0YZ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ54/entry", "sequence": { "sequence": "MAVRCAGSAWVRGLLGWAWPERWFAAGSAFPLSCIHTSTSLQKLGKWEKKNRIVYPPQLPGEPRRPAEIYHCRREIKYSKDKMWYLAKLIKGMSIDQALAQLEFNDKKGAKIIKEVLLEAQEMAVRNHNVEFKSNLHIAESLAGKGHYTKRIRLHGKGMFGIMKIVKCHYFVKLVEGPPPLPEPRKTGFDQAKEYVQQLRSRTLVHTL", "length": 208, "header": "tr|A0A8V0YZ54-1|A0A8V0YL12_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL22m OS=Gallus gallus OX=9031 GN=MRPL22 PE=1 SV=1 CANONICAL=A0A8V0YL12-1" }, "locus": { "chromosome": "13", "start_pos": 11619084, "end_pos": 11613282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037317.1", "url": "https://www.ensembl.org/id/ENSGALT00010037317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021637.1", "url": "https://www.ensembl.org/id/ENSGALP00010021637.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "P0C2C0-1", "protein_name": "Large ribosomal subunit protein uL22m", "gene_name": "Mrpl22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAALLRELGALWVPNLRIWTTQMLRVLPQSCIHTSTSLDISRRWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPRPEAPRTAVDHAKEYIQQLRSRTIIHTL", "length": 206 }, "evidence": [ { "id": "A0A8V0YL12", "url": "https://omabrowser.org/oma/group/A0A8V0YL12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SZX5-1", "protein_name": "Large ribosomal subunit protein uL22m", "gene_name": "MRPL22", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVILERLGALWVQNLRGKLALGILPQSHIHTSASLEISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPPEAPKTAVTHAKEYIQELRNRTIIHAL", "length": 204 }, "evidence": [ { "id": "A0A8V0YL12", "url": "https://omabrowser.org/oma/group/A0A8V0YL12/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BU88-1", "protein_name": "Large ribosomal subunit protein uL22m", "gene_name": "Mrpl22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALLRELGALRVPNLRIWATQTLRVLPPSCIHTSASLDISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKMIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEVPKTAVDHAKDYIQQLRSRTIIHTL", "length": 206 }, "evidence": [ { "id": "A0A8V0YL12", "url": "https://omabrowser.org/oma/group/A0A8V0YL12/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWU5-1", "protein_name": "Large ribosomal subunit protein uL22m", "gene_name": "MRPL22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVLGQLGALWIHNLRSRGKLALGVLPQSYIHTSASLDISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEPPKTAVAHAKEYIQQLRSRTIVHTL", "length": 206 }, "evidence": [ { "id": "A0A8V0YL12", "url": "https://omabrowser.org/oma/group/A0A8V0YL12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXB5-1", "protein_name": "Large ribosomal subunit protein uL22m", "gene_name": "mRpL22", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHKVIRQMSQLRLQAPQGAALLRSADSSSISPAISPVSPPALQSKSLHTAASAGMLCAKWNKYNYGPRKWLEYNKTVHPPQETDEEPRNAYVCHMRSNIKYSPDKMWYIAAFVRGMSVDEALKQLNFVLKKGATDVKETILEAQQIAVERHNVEYKSNLWIAESFVGKGRVFKGVRRHARGRFGKVEYKHCHYFVRLEEGEPPQHYYQEPQTPEQQYESWMEQMRSRKIINSL", "length": 233 }, "evidence": [ { "id": "A0A8V0YL12", "url": "https://omabrowser.org/oma/group/A0A8V0YL12/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12" } ], "pmid": "" }, { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YL27-1", "uniprot_ac": "A0A8V0YL27", "uniprot_id": "A0A8V0YL27_CHICK", "mass": { "chemical_mass": 32742.0, "monoisotopic_mass": 32742.0 }, "refseq": {}, "gene_names": [ { "name": "C2orf49", "type": "recommended", "evidence": [ { "id": "A0A8V0YL27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27" } ] } ], "protein_names": [ { "name": "tRNA-splicing ligase complex subunit ASW", "type": "recommended", "evidence": [ { "id": "A0A8V0YL27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity and may function toward other RNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27#function" }, { "database": "UniProtKB", "id": "ARBA00094271", "url": "https://www.uniprot.org/uniprotkb/ARBA00094271#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C2orf49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27", "locus": { "chromosome": "1", "start_pos": 135252726, "end_pos": 135239632, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013221", "url": "https://www.ensembl.org/id/ENSGALG00010013221" } ] } } ], "crossref": [ { "id": "A0A8V0YL27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL27", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL27", "url": "https://www.orthodb.org/?gene=A0A8V0YL27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28359:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28359:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15323", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15323", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRKPKHNPVTPSLLAELIGWGYVTRTASLPPLDPPPRARQPCGRPEVSRQGKKMAAQGRGRVGGGKEERVSARSDSELLLHPELLSEEFLLLTLEQKNILVKNDVKMDKDGLTDLYIQHAIPLPQRDLPKSRWGKMMEKKRKQNEPKSENKSVTAVEGLRKRPLIVFDGSSTSTSIKVKKTENGATDRLKPPPAGSITNTVRRLSAPSNASTYISASSLSEDAKLEVRNNEAKQNNISKTNSSVLVNLKTHPLSPVAGTTVVKLKRSVPKDESDLPNDLKPTEAKKKIQHVTWP", "length": 296, "header": "tr|A0A8V0YL27-1|A0A8V0YL27_CHICK Isoform 1 of tRNA-splicing ligase complex subunit ASW OS=Gallus gallus OX=9031 GN=C2orf49 PE=3 SV=1 CANONICAL=A0A8V0YL27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27/entry", "sequence": { "sequence": "MLRRKPKHNPVTPSLLAELIGWGYVTRTASLPPLDPPPRARQPCGRPEVSRQGKKMAAQGRGRVGGGKEERVSARSDSELLLHPELLSEEFLLLTLEQKNILVKNDVKMDKDGLTDLYIQHAIPLPQRDLPKSRWGKMMEKKRKQNEPKSENKSVTAVEGLRKRPLIVFDGSSTSTSIKVKKTENGATDRLKPPPAGSITNTVRRLSAPSNASTYISASSLSEDAKLEVRNNEAKQNNISKTNSSVLVNLKTHPLSPVAGTTVVKLKRSVPKDESDLPNDLKPTEAKKKIQHVTWP", "length": 296, "header": "tr|A0A8V0YL27-1|A0A8V0YL27_CHICK Isoform 1 of tRNA-splicing ligase complex subunit ASW OS=Gallus gallus OX=9031 GN=C2orf49 PE=3 SV=1 CANONICAL=A0A8V0YL27-1" }, "locus": { "chromosome": "1", "start_pos": 135251230, "end_pos": 135239831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031752.1", "url": "https://www.ensembl.org/id/ENSGALT00010031752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018584.1", "url": "https://www.ensembl.org/id/ENSGALP00010018584.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "embryonic morphogenesis", "id": "GO:0048598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048598", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YL28-1", "uniprot_ac": "A0A8V0YL28", "uniprot_id": "A0A8V0YL28_CHICK", "mass": { "chemical_mass": 99878.0, "monoisotopic_mass": 99878.0 }, "refseq": { "ac": "XP_416110", "name": "transcription factor E2F7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416110" }, "gene_names": [ { "name": "E2F7", "type": "recommended", "evidence": [ { "id": "A0A8V0YL28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ] }, { "name": "E2F7", "type": "synonym", "evidence": [ { "id": "XP_416110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416110" } ] } ], "protein_names": [ { "name": "Transcription factor E2F7", "type": "recommended", "evidence": [ { "id": "A0A8V0YL28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E2F7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416110" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416110.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416110" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "E2F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28", "locus": { "chromosome": "1", "start_pos": 38385664, "end_pos": 38402526, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013538", "url": "https://www.ensembl.org/id/ENSGALG00010013538" } ] } } ], "crossref": [ { "id": "A0A8V0YL28", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL28", "database": "AlphaFoldDB", "categories": [] }, { "id": "417868", "url": "https://www.ncbi.nlm.nih.gov/gene/417868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VCRQKME", "url": "https://omabrowser.org/oma/group/VCRQKME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL28", "url": "https://www.orthodb.org/?gene=A0A8V0YL28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL33", "url": "https://www.orthodb.org/?gene=A0A8V0YL33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12081:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12081:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6804116", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804116", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416110", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEANVLSLRDLAAVRPSRRGRAEAEAAQKENILDRSRMAPKTPIKNDPVDLSKQKGCTPDRNPMTPVKLIDKPQADPWTPTANLKMLISAASPDMRDREKKKELFRPIENSEQNDIPDSLQYDMVDDGTVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVASILGVGRRRIYDIVNVLESLHLVSRVAKNQYCWHGRHHLSQTLKTLQEAGELQYGELVTSQCKEQDTEYKSGEQKNEMVPDSQDRPLLDFAEPDCTSASANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDIAAKILIEENQDTVDYSKFKTKVRRLYDIANVLTSLCLIKKVHVTEERGRKPAFKWIGPVDFPGKTDEPRGHCPTSGPPAEAQRGACAPYQICATGKQRFTRHASFNGAQPCEGTKRKVSSEPNSPNRERQACIVNSDEYCSKMINLATVCRQKIEEDTRSKACATEAILNAVRNPSVTSPLSLLPVPGDSDFCANPLSQAVFPVVQADMPSLLLPKGVSSQALHPSSAAASKTENGKPPLLPSQPFLCFPSSSFFMLCGGLQENLSRESGSTEKAVPPEAQGAVPPANCQKRSSHRCTSPSAPTDDEEPAAKKQTVEQSDVPISLVVPKKPVESPKAGTAPGSGCASAVHLEAFHLDLSSPAAPETADKKSTKPLDSQEQEKWSQNKDLDEPSPGKDHISKGNANQPFVPQYLYVQPAAGLSSFNFLFSANQAPSAIGLAASQLPSLSVPCVMVPSAALASFPLICSPAIPSPLSPVPDGSSAAASMNISMPGLASTTPVFIGTTAVVTPNASPSPSVDPQQTAHPAAHPRPVLARSCSAVKLDSPVCVGHPVTLLKLQQPSSTPVTPKSVRPARHEAFFKTPGSLGDPGTWKKGEGNQTRSASSVQRRLEISSTSTD", "length": 923, "header": "tr|A0A8V0YL28-1|A0A8V0YL28_CHICK Isoform 1 of Transcription factor E2F7 OS=Gallus gallus OX=9031 GN=E2F7 PE=3 SV=1 CANONICAL=A0A8V0YL28-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28/entry", "sequence": { "sequence": "MEANVLSLRDLAAVRPSRRGRAEAEAAQKENILDRSRMAPKTPIKNDPVDLSKQKGCTPDRNPMTPVKLIDKPQADPWTPTANLKMLISAASPDMRDREKKKELFRPIENSEQNDIPDSLQYDMVDDGTVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVASILGVGRRRIYDIVNVLESLHLVSRVAKNQYCWHGRHHLSQTLKTLQEAGELQYGELVTSQCKEQDTEYKSGEQKNEMVPDSQDRPLLDFAEPDCTSASANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDIAAKILIEENQDTVDYSKFKTKVRRLYDIANVLTSLCLIKKVHVTEERGRKPAFKWIGPVDFPGKTDEPRGHCPTSGPPAEAQRGACAPYQICATGKQRFTRHASFNGAQPCEGTKRKVSSEPNSPNRERQACIVNSDEYCSKMINLATVCRQKIEEDTRSKACATEAILNAVRNPSVTSPLSLLPVPGDSDFCANPLSQAVFPVVQADMPSLLLPKGVSSQALHPSSAAASKTENGKPPLLPSQPFLCFPSSSFFMLCGGLQENLSRESGSTEKAVPPEAQGAVPPANCQKRSSHRCTSPSAPTDDEEPAAKKQTVEQSDVPISLVVPKKPVESPKAGTAPGSGCASAVHLEAFHLDLSSPAAPETADKKSTKPLDSQEQEKWSQNKDLDEPSPGKDHISKGNANQPFVPQYLYVQPAAGLSSFNFLFSANQAPSAIGLAASQLPSLSVPCVMVPSAALASFPLICSPAIPSPLSPVPDGSSAAASMNISMPGLASTTPVFIGTTAVVTPNASPSPSVDPQQTAHPAAHPRPVLARSCSAVKLDSPVCVGHPVTLLKLQQPSSTPVTPKSVRPARHEAFFKTPGSLGDPGTWKKGEGNQTRSASSVQRRLEISSTSTD", "length": 923, "header": "tr|A0A8V0YL28-1|A0A8V0YL28_CHICK Isoform 1 of Transcription factor E2F7 OS=Gallus gallus OX=9031 GN=E2F7 PE=3 SV=1 CANONICAL=A0A8V0YL28-1" }, "locus": { "chromosome": "1", "start_pos": 38402401, "end_pos": 38386668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032565.1", "url": "https://www.ensembl.org/id/ENSGALT00010032565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019290.1", "url": "https://www.ensembl.org/id/ENSGALP00010019290.1" } ] } }, { "isoform_ac": "A0A8V0YL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL33/entry", "sequence": { "sequence": "MEANVLSLRDLAAVRPSRRGRAEAEAAQKENILDRSRMAPKTPIKNDPVDLSKQKGCTPDRNPMTPVKLIDKPQADPWTPTANLKMLISAASPDMRDREKKKELFRPIENSEQNDIPDSLQYDMVDDGTVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVASILGVGRRRIYDIVNVLESLHLVSRVAKNQYCWHGRHHLSQTLKTLQEAGELQYGELVTSQCKEQDTEYKSGEQKNEMVPDSQDRPLLDFAEPDCTSASANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDIAAKILIEENQDTVDYSKFKTKVRRLYDIANVLTSLCLIKKVHVTEERGRKPAFKWIGPVDFPGKTDEPRGHCPTSGPPAEAQRGACAPYQICATGKQRFTRHASFNGAQPCEGTKRKVSSEPNSPNRERQACIVNSDEYCSKMINLATVCRQKIEEDTRSKACATEAILNAAVFPVVQADMPSLLLPKGVSSQALHPSSAAASKTENGKPPLLPSQPFLCFPSSSFFMLCGGLQENLSRESGSTEKAVPPEAQGAVPPANCQKRSSHRCTSPSAPTDDEEPAAKKQTVEQSDVPISLVVPKKPVESPKAGTAPGSGCASAVHLEAFHLDLSSPAAPETADKKSTKPLDSQEQEKWSQNKDLDEPSPGKDHISKGNANQPFVPQYLYVQPAAGLSSFNFLFSANQAPSAIGLAASQLPSLSVPCVMVPSAALASFPLICSPAIPSPLSPVPDGSSAAASMNISMPGLASTTPVFIGTTAVVTPNASPSPSVDPQQTAHPAAHPRPVLARSCSAVKLDSPVCVGHPVTLLKLQQPSSTPVTPKSVRPARHEAFFKTPGSLGDPGTWKKGEGNQTRSASSVQRRLEISSTSTD", "length": 895, "header": "tr|A0A8V0YL33-1|A0A8V0YL33_CHICK Computationally mapped isoform of Transcription factor E2F7 OS=Gallus gallus OX=9031 GN=E2F7 PE=3 SV=1 CANONICAL=A0A8V0YL28-1" }, "locus": { "chromosome": "1", "start_pos": 38402401, "end_pos": 38386668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032570.1", "url": "https://www.ensembl.org/id/ENSGALT00010032570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019295.1", "url": "https://www.ensembl.org/id/ENSGALP00010019295.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6804116", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804116", "resource": "Reactome", "description": "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QSW6-1", "protein_name": "Transcription factor E2F7", "gene_name": "E2F7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVNCLTLKDLISPRQPRRDFAIEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKLFTPERNPMTPVKLVDRQQAEPWTPTANLKVLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQRYEEQMAHLQQKELDLLEYKCGERKRDGCAESQDPHLLDFSEPDCPSSSASSRKDKSLRTMSQKFVMLLLASKPKIVTLGAAAKVLTEGSQDTADHSKLKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSPSDEELVDVSASVLPELKRDTYGHIQFCAKQKLARHGSLNSVQASEKIQRKVNSEPSSPHRDKQESGGYSLEIGSLAAVYRQKIEDTSRGGAFARRRAMPPSDGQDAAAAPLPSRSADSESCASPPANRVLSGAPTDSQAFSAQNGRGAVSLGPAASDAAESLQPALLPGQPLVYVPSAPLFMLCGGLQEAPAPGAGPERDSRGWEVTAAEHASSPSVPKRLGEERRPQEEEGPATKRQSRDCEEGPLSLVMPKKPSDPTDIASSKNVETRGSAPQEDLRRNGQLSAAKEASGKAVANCFVSAEWGNPSRNSEIEKPLKENESTKEPSLLQYLYVQSPAALNGFNVLLSGHQTPPAVGASPGPLPPLSVPCMVVPSPTLGPFPLVYSPAVPGRVPAAPGPLPHAGPAPFGLSGLGSAAPLLIGPAAAGNPKPPPLPAADAPLQGPRALSLSPVTSRSLRVTQPESPVYRGHQASVAKPQQSPAPVTPKSVRCTQRDTFFKTPGSLGDPVLRKRERNPSRNTTSAQRRLEIPSGGSD", "length": 908 }, "evidence": [ { "id": "A0A8V0YL28", "url": "https://omabrowser.org/oma/group/A0A8V0YL28/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BE02-1", "protein_name": "Transcription factor E2F7", "gene_name": "E2F7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVNCLTLKDLISRPPRLDFAIEDGENAQKENIFVDLSRMAPKTPIKNEPIDLSKQKIFTPERNPITPVKLVDRQQVEPWTPTANLKILISAASPDIRDREKKKELFRPIENKDDVFTDSLQLDAVDDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYSWHGRHSLPKTLRNLQRLGEKQKYEEQMAHLQQKELNPIDHKSGERRRDGCPDSQDPQLLDFPEPDCPSSSANSRKDKSLKIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDIPDHSKFKTKVRRLYDIANVLTSLMLIKKVHVTEDRGRKPAFKWIGPVDFSSTDDDLVDVSTPVLPELKKEIYGHVQFCAKQKLARHSSFNSEQASERTQRKVNSEPSSPYRQKQGLGVYSLEIGSLAAVSRQKMEDNSETVAFASQNMMPLPSSLDPAAPLPSPSVDSEYRVSPLCHQALSAAQTDLKALPAQNGLNGQGGVSLASMALDVEHQPQPLAAAQPLLYVPPAPLFMLCGGLQEGLSPGSGSGSGSVGGGSEVTAAEQPPMPSGQKRLSKERRLQEEEEEPATKRQCRDHEDGPLSLVMPKKPSDSADIASPKTSENRASAPHEDTHMNGQLSAAKAVSGKATTNGFVSSEWGNPCSNTEIEKPSEENESTKGPSPLQYLYVQPPAGLNGLSVLLPSSQSPHAVGLPVGPLPSLSIQYMVLPSPALSGFPVLCSPTMPGPVSSAPSPLPNVGPVNFGLPGLGSTAHLLIGPAAMVNPKSSTLPSTDPQLQGPCSLHLSPVMSRSHGSVQPGSPAYGSLPAATVKLQQSPVPVTPKSIRCTHQETFFKTPGSLGDPVLRRKERNQSRSSSSAQRRLEISSGGTD", "length": 911 }, "evidence": [ { "id": "A0A8V0YL28", "url": "https://omabrowser.org/oma/group/A0A8V0YL28/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6S7F2-1", "protein_name": "Transcription factor E2F7", "gene_name": "E2f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVNCLTLKDLISPRQTRLDFAIEDAENAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPDRNPITPVKPVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKEDAFVNSLQLDVAGDGAVDEYEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMGYRFGERRKDGSPDPRDPHLLDFSEADYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSASILPELKKEAYGQIRVCAKERLVRYGSFNTVHTSEKIQRKVSSEPSSPQGERQGSAYSLEIGSLAAIYRQKVEDNSQEEAFVSNTAVPPASILDPALSMDSEYCVKPLAQPVFSVAQTDLPAFSAQNGPSGQVGVPVPSAASDTENLKPALLAGQPLVYVPSTQLFMLYGSVQEGLSPESRSEEDGGGSDVPADLSVTPSAQKRLCEERDPQEEEDEPAMKRQSQEFEDSPLSLVMPKKPSSSTDLACPVTMGNGSSPPLEDACVKGQLPAAEEVTGKAAPNCYVASECGNPARNPDTEKPSNENEITKDPSLMQYLYVQSPAGLNGFNMVLPGTQTPHTVAPSPAQLPSFGVPCMFLQSPGLGPFPVLYSPAIPGPISSAPGTHPNPGPMNFGLSTLASASHLLISPAAMVNPKPSTLPCTDPQLRCQPSLNLNPVMPGSHGVIHPESPCYVRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPVFRRKERNQSRNTSSAQRRLEISSSGPD", "length": 904 }, "evidence": [ { "id": "A0A8V0YL28", "url": "https://omabrowser.org/oma/group/A0A8V0YL28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AV8-1", "protein_name": "Transcription factor E2F7", "gene_name": "E2F7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKFTPERNPITPVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERIQRKVNSEPSSPYREEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPVAPFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRLEIPSGGAD", "length": 911 }, "evidence": [ { "id": "A0A8V0YL28", "url": "https://omabrowser.org/oma/group/A0A8V0YL28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "positive regulation of DNA endoreduplication", "id": "GO:0032877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "negative regulation of cytokinesis", "id": "GO:0032466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032466", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "hepatocyte differentiation", "id": "GO:0070365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070365", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL28" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": 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"Protein" ] } ], "sequence": { "sequence": "MYLARQAMDKIKVPDRLPFYMGIRQGRDEDFGAFIDKVAGAIEKAGVPEYMRGVMLKQCALQNCNSTARSILSTLRSNWTIEEALEKLSSVPVGPQAFLVEAIKELGAGLKAQAEASHNQVLAALASLQASVITNLGPRSPVAGRIKCYRCGGMGHMRRQCQATGSWCHTCRMDNHNTNACRRWSGNTQPSARKKRRLRADTSSRFQPAAALQPATPGCLGLDLAAAVTTTLMTTKPERVSTGIRGPVMINGTAVGALLLGRSSASMLGLFVLPGVIDADFQGEIQIMVYTPFPPIKIEKGQRIAQLVPLEQLTKALTPCQSSPRGEQGFGSSGGLALLSLNLHDRPKKPVTLKYREEENKLQGLLDTGADNSIVSPEIWPPQWPLQAAIATVTGIGRLSLAKKSPPLQIHLDEQVVHTSVSVAPLPPTVQCLIGRNVLSQLGALQPALPNPAMLPYNWPLLISDLKDCFFTITLHPQDTKRFAFTLPALNQEHPDQRFEWTVLPQGMKNSPMLCQLYVDHALQPLRREWKQMVIYHCMDDILFAQPEAFTQERIWQIEKTLNREGLMIAPEKVQLSAPRKYLGWTLTNTIVTPQKLQLDTKIETLHDAQRLLGDLKWLSPVVGIPNELLESLRPLLRGTDPAQPVTVTSQHKRLLQQIMDCIIHGSVRRRDPDLPIQVMVWYGPKYLLGALAQSKKKMGEVWVLEWICPSLQQSKTLLQKIELLTEVIKKGRERTLQIIGMEPVCVQLPMQKDTLTWYVQHSPELQDALLGAGSTVSMEKIPNVPLHWIGQWSWLRIPKQHETPLQNTITAYTDAGQKSRTAAVTWQQGGSWRHHLIAADDKDLLQTLELVAVVWAMMNLIGPLNVVTDSLYVAGVCHQIEEAYIKEVQNRRLYELFVQLQRAIRIREHSYAVIHVRGHKWEIDLGEGNARADCLVSLAQRPLVSQHVLAREAHSMFRQNAKGLRREYQITYEDAKVIVRSCPVCSHHNGSMGLGLGVKPRGLKANENRQMDVTHVGEFGQLKYVHVSIDTYSHFMWATAQPGEKAMYVERHLSCCFAVMGISLQIKTDNGPAYTSCRLGEFQQTWGVKHSTGIPNSPTGQAIVEQGNCGWTADPARSCFSPPGSVQVKQLLWITVSHRTMMGVGERNAEL", 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"length": 1152, "header": "tr|A0A8V0YL38-1|A0A8V0YL38_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YL38-1" }, "locus": { "chromosome": "7", "start_pos": 112094, "end_pos": 108639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032580.1", "url": "https://www.ensembl.org/id/ENSGALT00010032580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019301.1", "url": "https://www.ensembl.org/id/ENSGALP00010019301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL38" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL38", "url": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YL43-1", "uniprot_ac": "A0A8V0YL43", "uniprot_id": "A0A8V0YL43_CHICK", "mass": { "chemical_mass": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040513305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL1RL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL43", "locus": {} } ], "crossref": [ { "id": "A0A8V0YL43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL43", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05756", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05756", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20994", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20994", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418716", "url": "https://www.ncbi.nlm.nih.gov/gene/418716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL43", "url": "https://www.orthodb.org/?gene=A0A8V0YL43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040513305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGKRKKFISLSWQSVGNMTAKIFSCKITTAFLSLIIAEKCGAYDVMFKHSLVPDGQPLVIKCSLEKSFSFKSGDCNLTWYKVGNKTAVPRDKLARIHQQKSLIWFLPAILEDSGNYECVISCRNLTSCSKMSTEVTVFERTDGLCLNEDFAVEEVVFTSSSARVVCPHLDHFRNEENILPVRWYKDCQLLEGKRFAFLNSDLVIFNVTVQDQGNYTCKTTYTYNGKQYDIARDISLIVEVSPPKMPPEISYPQNNSIEVELGSEVTVDCNTTGADGFEVFWTGNGVYNDVFYVSRIFARPYKEETAYDGRPMYSLKLIISEVHSEDYEQPFVCQASNAFGQVASYIILKHRVPDVPRWLTGGLVSLLLLMFIILIVYKMFKIELVLWYRNSRCAFVSKEDGKIYDACVLYTKGSGGSNFCRLETFVLRILPSVLEQQCGYNLFILGRDDLPGEAVVSVADETFKQSRRLMIILGSETFSCVQLEDASEQQLAMYSALIRDETQVILIEMDGTQDYASMPESIRYIKQKHGAIQWKGDFSEKSCSANTRFWKNVRYQMPAKKKVSFSEVYLSPHTLNNSAAKAN", "length": 584, "header": "tr|A0A8V0YL43-1|A0A8V0YL43_CHICK Isoform 1 of Interleukin 1 receptor like 2 OS=Gallus gallus OX=9031 GN=IL1RL2 PE=3 SV=1 CANONICAL=A0A8V0YL43-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL43/entry", "sequence": { "sequence": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YL71-1", "uniprot_ac": "A0A8V0YL71", "uniprot_id": "A0A8V0YL71_CHICK", "mass": { "chemical_mass": 74176.0, "monoisotopic_mass": 74176.0 }, "refseq": { "ac": "XP_046756426", "name": "polycystic kidney disease 2-like 2 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756426" }, "gene_names": [ { "name": "PKD2L2", "type": "recommended", "evidence": [ { "id": "A0A8V0YL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ] }, { "name": "PKD2L2", "type": "synonym", "evidence": [ { "id": "XP_046756426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756426" } ] } ], "protein_names": [ { "name": "Polycystin 2 like 2, transient receptor potential cation channel", "type": "synonym", "evidence": [ { "id": "A0A8V0YL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71/entry#names_and_taxonomy" } ] }, { "name": "polycystic kidney disease 2-like 2 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046756426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756426" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PKD2L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71", "locus": { "chromosome": "13", "start_pos": 14009533, "end_pos": 14019933, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015564", "url": "https://www.ensembl.org/id/ENSGALG00010015564" } ] } } ], "crossref": [ { "id": "A0A8V0YL71", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006120", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006120", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416298", "url": "https://www.ncbi.nlm.nih.gov/gene/416298", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416298", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416298", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVDFWKF", "url": "https://omabrowser.org/oma/group/MVDFWKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL71", "url": "https://www.orthodb.org/?gene=A0A8V0YL71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUB0", "url": "https://www.orthodb.org/?gene=A0A8V0YUB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZA9", "url": "https://www.orthodb.org/?gene=A0A8V0YZA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NE51", "url": "https://www.orthodb.org/?gene=F1NE51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10877", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10877", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10877:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10877:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046756426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE51", "url": "https://www.uniprot.org/uniprotkb/F1NE51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE51-1", "url": "https://www.uniprot.org/uniprotkb/F1NE51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAAALQPVVAVRRSGGGATTARVSYSKERELKTTLLELLIYITFLVTLSLMTFGMVSTNMYYLNKVMEDLFVEQTSSESSGINFRSIKSQADFWEFAEGPLLDGLYWSTWYDNRTVTDLKNASYIFYENLLLGVAQIRQLKVRNNTCSIYPYFQPFLKSCYSRYSYKAEDKSDFGLKDEPEWKYVSASSFSPWYWGSVGFYRSGGFIVTLPRSKQESMEKLASLRKNGWITHGTRAVFIDFSTFNANINLFCIVRLVVEFPATGGALTSFQIHSVKLLRYVSYYDYFLASCEVAFCLFILTFIIQEAIEITRLKMEYFRSAWNWLDMLLIAVSILAICFNIYRTIEVSLLMEELLSNAHVYPDFYFLAFWQVIYDNVIAINVFFAWIKIFKYVSFSKTMTQLSSTLSRCAKDIIGFAIMFFIIFIAYAQFSHLVFGPQVDDFSTFQNCIFSQFRIVLGDFNFESLEVNSILGPIYYISFVFFVFFVLLNMFLAIINDTYSEVKADFAVIPNEELHIADLFRQSYNKALVKLKLRKPETDLGDENLERSKEFPSTKRKDTSKPSKGGSPHEKRHPKPPKLQKESLHRSDSVAASQSSVSPEEFQRLLRQTSELEKELNSANAKLSRIMKSMQQLKNASGKTTQ", "length": 644, "header": "tr|A0A8V0YL71-1|A0A8V0YL71_CHICK Isoform 1 of Polycystin 2 like 2, transient receptor potential cation channel OS=Gallus gallus OX=9031 GN=PKD2L2 PE=3 SV=1 CANONICAL=A0A8V0YL71-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71/entry", "sequence": { "sequence": "MEPAAALQPVVAVRRSGGGATTARVSYSKERELKTTLLELLIYITFLVTLSLMTFGMVSTNMYYLNKVMEDLFVEQTSSESSGINFRSIKSQADFWEFAEGPLLDGLYWSTWYDNRTVTDLKNASYIFYENLLLGVAQIRQLKVRNNTCSIYPYFQPFLKSCYSRYSYKAEDKSDFGLKDEPEWKYVSASSFSPWYWGSVGFYRSGGFIVTLPRSKQESMEKLASLRKNGWITHGTRAVFIDFSTFNANINLFCIVRLVVEFPATGGALTSFQIHSVKLLRYVSYYDYFLASCEVAFCLFILTFIIQEAIEITRLKMEYFRSAWNWLDMLLIAVSILAICFNIYRTIEVSLLMEELLSNAHVYPDFYFLAFWQVIYDNVIAINVFFAWIKIFKYVSFSKTMTQLSSTLSRCAKDIIGFAIMFFIIFIAYAQFSHLVFGPQVDDFSTFQNCIFSQFRIVLGDFNFESLEVNSILGPIYYISFVFFVFFVLLNMFLAIINDTYSEVKADFAVIPNEELHIADLFRQSYNKALVKLKLRKPETDLGDENLERSKEFPSTKRKDTSKPSKGGSPHEKRHPKPPKLQKESLHRSDSVAASQSSVSPEEFQRLLRQTSELEKELNSANAKLSRIMKSMQQLKNASGKTTQ", "length": 644, "header": "tr|A0A8V0YL71-1|A0A8V0YL71_CHICK Isoform 1 of Polycystin 2 like 2, transient receptor potential cation channel OS=Gallus gallus OX=9031 GN=PKD2L2 PE=3 SV=1 CANONICAL=A0A8V0YL71-1" }, "locus": { "chromosome": "13", "start_pos": 14019712, "end_pos": 14009703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037463.1", "url": "https://www.ensembl.org/id/ENSGALT00010037463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021697.1", "url": "https://www.ensembl.org/id/ENSGALP00010021697.1" } ] } }, { "isoform_ac": "A0A8V0YUB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB0/entry", "sequence": { "sequence": "MEPAAALQPVVAVRRSGGGATTARVSYSKERELKTTLLELLIYITFLVTLSLMTFGMFAEGPLLDGLYWSTWYDNRTVTDLKNASYIFYENLLLGVAQIRQLKVRNNTCSIYPYFQPFLKSCYSRYSYKAEDKSDFGLKDEPEWKYVSASSFSPWYWGSVGFYRSGGFIVTLPRSKQESMEKLASLRKNGWITHGTRAVFIDFSTFNANINLFCIVRLVVEFPATGGALTSFQIHSVKLLRYVSYYDYFLASCEVAFCLFILTFIIQEAIEITRLKMEYFRSAWNWLDMLLIAVSILAICFNIYRTIEVSLLMEELLSNAHVYPDFYFLAFWQVIYDNVIAINVFFAWIKIFKYVSFSKTMTQLSSTLSRCAKDIIGFAIMFFIIFIAYAQFSHLVFGPQVDDFSTFQNCIFSQFRIVLGDFNFESLEVNSILGPIYYISFVFFVFFVLLNMFLAIINDTYSEVKADFAVIPNEELHIADLFRQSYNKALVKLKLRKPETDLGDENLESKEFPSTKRKDTSKPSKGGSPHEKRHPKPPKLQKESLHRSDSVAASQSSVSPEEFQRTSPYGCPEGDKDCKALCLGQGISGLKALGSRQNTSEQTQRLQI", "length": 608, "header": "tr|A0A8V0YUB0-1|A0A8V0YL71_CHICK Computationally mapped isoform of Polycystin 2 like 2, transient receptor potential cation channel OS=Gallus gallus OX=9031 GN=PKD2L2 PE=3 SV=1 CANONICAL=A0A8V0YL71-1" }, "locus": { "chromosome": "13", "start_pos": 14019712, "end_pos": 14009872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037419.1", "url": "https://www.ensembl.org/id/ENSGALT00010037419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021675.1", "url": "https://www.ensembl.org/id/ENSGALP00010021675.1" } ] } }, { "isoform_ac": "A0A8V0YZA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZA9/entry", "sequence": { "sequence": "MEPAAALQPVVAVRRSGGGATTARVSYSKERELKTTLLELLIYITFLVTLSLMTFGMVSTNMYYLNKVMEDLFVEQTSSESSGINFRSIKSQADFWEFAEGPLLDGLYWSTWYDNRTVTDLKNASYIFYENLLLGVAQIRQLKVRNNTCSIYPYFQPFLKSCYSRYSYKAEDKSDFGLKDEPEWKYVSASSFSPWYWGSVGFYRSGGFIVTLPRSKQESMEKLASLRKNGWITHGTRAVFIDFSTFNANINLFCIVRLVVEFPATGGALTSFQIHSVKLLRYVSYYDYFLASCEVAFCLFILTFIIQEAIEITRLKMEYFRSAWNWLDMLLIAVSILAICFNIYRTIEVSLLMEELLSNAHVYPDFYFLAFWQVIYDNVIAINVFFAWIKIFKYVSFSKTMTQLSSTLSRCAKDIIGFAIMFFIIFIAYAQFSHLVFGPQVDDFSTFQNCIFSQFRIVLGDFNFESLEVNSILGPIYYISFVFFVFFVLLNMFLAIINDTYSEVKADFAVIPNEELHIADLFRQSYNKALVKLKLRKPETDLGDENLERNFHPLKERILPSLPKEAALMKRCLHQP", "length": 576, "header": "tr|A0A8V0YZA9-1|A0A8V0YL71_CHICK Computationally mapped isoform of Polycystin 2 like 2, transient receptor potential cation channel OS=Gallus gallus OX=9031 GN=PKD2L2 PE=3 SV=1 CANONICAL=A0A8V0YL71-1" }, "locus": { "chromosome": "13", "start_pos": 14019712, "end_pos": 14010226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037455.1", "url": "https://www.ensembl.org/id/ENSGALT00010037455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021693.1", "url": "https://www.ensembl.org/id/ENSGALP00010021693.1" } ] } }, { "isoform_ac": "F1NE51-1", "url": "https://www.uniprot.org/uniprotkb/F1NE51/entry", "sequence": { "sequence": "MRSGATTARVSYSKERELKTTLLELLIYITFLVTLSLMTFGMVSTNMYYLNKVMEDLFVEQTSSESSGINFRSIKSQADFWEFAEGPLLDGLYWSTWYDNRTVTDLKNASYIFYENLLLGVAQIRQLKVRNNTCSIYPYFQPFLKSCYSRYSYKAEDKSDFGLKDEPEWKYVSASSFSPWYWGSVGFYRSGGFIVTLPRSKQESMEKLASLRKNGWITHGTRAVFIDFSTFNANINLFCIVRLVVEFPATGGALTSFQIHSVKLLRYVSYYDYFLASCEVAFCLFILTFIIQEAIEITRLKMEYFRSAWNWLDMLLIAVSILAICFNIYRTIEVSLLMEELLSNAHVYPDFYFLAFWQVIYDNVIAINVFFAWIKIFKYVSFSKTMTQLSSTLSRCAKDIIGFAIMFFIIFIAYAQFSHLVFGPQVDDFSTFQNCIFSQFRIVLGDFNFESLEVNSILGPIYYISFVFFVFFVLLNMFLAIINDTYSEVKADFAVIPNEELHIADLFRQSYNKALVKLKLRKPETDLGDENLESKEFPSTKRKDTSKPSKGGSPHEKRHPKPPKLQKESLHRSDSVAASQSSVSPEEFQRLLRQTSELEKELNSANAKLSRIMKSMQQLKNASGKTTQ", "length": 628, "header": "tr|F1NE51-1|A0A8V0YL71_CHICK Computationally mapped isoform of Polycystin 2 like 2, transient receptor potential cation channel OS=Gallus gallus OX=9031 GN=PKD2L2 PE=3 SV=4 CANONICAL=A0A8V0YL71-1" }, "locus": { "chromosome": "13", "start_pos": 14019517, "end_pos": 14009703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037437.1", "url": "https://www.ensembl.org/id/ENSGALT00010037437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021682.1", "url": "https://www.ensembl.org/id/ENSGALP00010021682.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416298", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MJ88-1", "protein_name": "Polycystin-2-like protein 2", "gene_name": "Pkd2l2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEASWWYRGGTSKHDLHYRREAEVNTTFEELLLYFIFLITLCILTFGMVNPHMYYLNKVMSSLFVDTALPDDEKSSFRSIRSITDFWKFVEGPLLEGLYWDSWYNNQKLYNLKNSSRIYYENVLLGVPRVRQLRVRNNTCKVYSAFKSLISDCYGKYTTENEEVSDFGLKNDTEWKYSTSPANAPWHWGFVGVYRDGGYMFTLSKSKSHTQTKLIDLRLNSWITRGTRVVFIDFSLYNANINLFCIVRLVAEFPATGGLLTSWQFYSVKLLRYVTHYDYFIASCEIIFCIFLFVFITQELRKLNELKSAYFKSIWNWLEMLLLALCFLAVSFYAYCHMQNFLLLERLLKNTENYPNFYFLAYWHIYYNNIIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYAIGRRPDFELGKIIKKSYFNVLEKLGLKKAQDNEDKKMKTTGDLAQQARKEGFNESEIQQAEHMKTWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYISLKLNQVMRKLQ", "length": 622 }, "evidence": [ { "id": "A0A8V0YL71", "url": "https://omabrowser.org/oma/group/A0A8V0YL71/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A828-1", "protein_name": "Polycystin-2-like protein 2", "gene_name": "Pkd2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEATWWHRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGTVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLVEGLYWDSWYGNTQLDSVKNSSLIYYENILLGVPRVRQLRVRNSTCQVYPAFQSLASDCYNKYTAENEDFSDFGLKHDPEWRHSAPSSTAPWHWGFVGVYRDGGYMVTLSKSKSETKAKLADLRQNNWIGRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGILTSWQFYSVKLIRYVSYYDHFIASCEIIFCIFLLVFITQELRKLNEFKSAYFRSVWNWIELLLLVLCFLAVSFYAYCNVQCFLLLGQLLRSTESYPDFYFLAYWHIYYNNIIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFFAYAQLAFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGSIIKKSCFNILEKLRLRKAQNNEDKKMKTSVDLAQARKEGFDESEIQEARQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYLSLKLNQVMRKLH", "length": 621 }, "evidence": [ { "id": "A0A8V0YL71", "url": "https://omabrowser.org/oma/group/A0A8V0YL71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LK18-1", "protein_name": "Polycystin-2-like protein 2", "gene_name": "PKD2L2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEASRWHLGGTPKPKLQYRKDVEIRTTLQELLLYLIFLINLCILTFGMVNPHMYYLNKVMASLFLDTSVPGEERTNFRSIRSITDFWKFMEGPFLEGLYWDSWYNSNDLYDLKNTSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTSKNEDLSDFGLKSDSEWKYSTPNRSSPWHWGFVGIYRNGGYIFTLSKSKSETRSKFINLRLNSWITRSTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSNYDYFIASCEITFCIFLIVFTTQEIQKMREFKSAYFQSIWNWLELLLLVLCFVAIAFNVYCNIQISLLLGQLLKNTEKYSDFYFLAYWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCMKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIILGDFNFAGIQQANRILGPIYFITFIFFVFFVLLNMFLAIINDTYAEVKADYSIGRRPDFELGKMIKKSYNNALEKLKLKKAQKDESKESKKSEDLAEQARREGFDETEIQSAEKMKKWKERLEKKYYSTEIQDDYQPVTQQEFRDLFLYAVELEKELHYVSLKLNRVMRKVSALQY", "length": 626 }, "evidence": [ { "id": "A0A8V0YL71", "url": "https://omabrowser.org/oma/group/A0A8V0YL71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JLG4-1", "protein_name": "Polycystin-2-like protein 2", "gene_name": "Pkd2l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEATWWYRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRTAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLKKAQAKEEKKMQTTDLAQRARRDGFDESEIQEAEQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAVELEKELHYVSLKLNQLMRKLH", "length": 621 }, "evidence": [ { "id": "A0A8V0YL71", "url": "https://omabrowser.org/oma/group/A0A8V0YL71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZM6-1", "protein_name": "Polycystin-2-like protein 2", "gene_name": "PKD2L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYAVELEKELHYINLKLNQVVRKVSAL", "length": 624 }, "evidence": [ { "id": "A0A8V0YL71", "url": "https://omabrowser.org/oma/group/A0A8V0YL71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "detection of mechanical stimulus", "id": "GO:0050982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" }, { "id": "PF20519", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20519" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 280, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL71" }, { "id": "PF08016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin cation channel PKD1/PKD2", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 504, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 637, "end_pos": 639 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLB1-1", "uniprot_ac": "A0A8V0YLB1", "uniprot_id": "A0A8V0YLB1_CHICK", "mass": { "chemical_mass": 49572.0, "monoisotopic_mass": 49572.0 }, "refseq": { "ac": "XP_417443", "name": "solute carrier family 52, riboflavin transporter, member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417443" }, "gene_names": [ { "name": "SLC52A3", "type": "recommended", "evidence": [ { "id": "A0A8V0YLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ] }, { "name": "SLC52A3", "type": "synonym", "evidence": [ { "id": "XP_417443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417443" } ] } ], "protein_names": [ { "name": "Riboflavin transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0YLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 52, riboflavin transporter, member 3", "type": "synonym", "evidence": [ { "id": "XP_417443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417443.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417443" } ] }, { "annotation": "Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1#function" }, { "database": "UniProtKB", "id": "RU368035", "url": "https://www.uniprot.org/uniprotkb/RU368035#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC52A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1", "locus": { "chromosome": "20", "start_pos": 10256229, "end_pos": 10252439, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013779", "url": "https://www.ensembl.org/id/ENSGALG00010013779" } ] } } ], "crossref": [ { "id": "A0A8V0YLB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "419270", "url": "https://www.ncbi.nlm.nih.gov/gene/419270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419270", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGAAAQM", "url": "https://omabrowser.org/oma/group/CGAAAQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB1", "url": "https://www.orthodb.org/?gene=A0A8V0YLB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12929:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12929:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196843", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "35015", "url": "https://www.rhea-db.org/rhea/35015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLTHLLACAFGMGSWVAINGLWVELPLLVTVLPEQWDLPSYITIIIQMANVGPLFVTLMHRFWPGSLKEVVVIYVVVSVGIVACLLLAFLWDYTSPIVGTTHSTAFLILTFFLALVDCTSSVTFLPFMMQLQAQYLTTFFIGEGLSGLIPALIALGQGSGISSCANVSQMVNITSDNETMEGTIFRMETRYLPARFSTLIFFLLMTAMMVACLVAFFFLTRQPKVWELSQQQLCPSTIILNSFDQILEDDGGTGRGEGYSCPKSTKRPMETHPEKVSYSVAKLAFIYLLITWVSSLTNGVLPSVQSYSCLPYGNTAYHLSATLSSMANPLACIVAMVLPSRSLALLGTLSLAGTGFGAYNMAIAVMSPCPLLQHSQWGDAIIILSWVLFTGTLSYVKVMAGVILRSRSHSALVWYGALEQLGSLLGALLMFPLVNIYGFFQSADYCSLQCPV", "length": 454, "header": "tr|A0A8V0YLB1-1|A0A8V0YLB1_CHICK Isoform 1 of Riboflavin transporter OS=Gallus gallus OX=9031 GN=SLC52A3 PE=3 SV=1 CANONICAL=A0A8V0YLB1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1/entry", "sequence": { "sequence": "MSLLTHLLACAFGMGSWVAINGLWVELPLLVTVLPEQWDLPSYITIIIQMANVGPLFVTLMHRFWPGSLKEVVVIYVVVSVGIVACLLLAFLWDYTSPIVGTTHSTAFLILTFFLALVDCTSSVTFLPFMMQLQAQYLTTFFIGEGLSGLIPALIALGQGSGISSCANVSQMVNITSDNETMEGTIFRMETRYLPARFSTLIFFLLMTAMMVACLVAFFFLTRQPKVWELSQQQLCPSTIILNSFDQILEDDGGTGRGEGYSCPKSTKRPMETHPEKVSYSVAKLAFIYLLITWVSSLTNGVLPSVQSYSCLPYGNTAYHLSATLSSMANPLACIVAMVLPSRSLALLGTLSLAGTGFGAYNMAIAVMSPCPLLQHSQWGDAIIILSWVLFTGTLSYVKVMAGVILRSRSHSALVWYGALEQLGSLLGALLMFPLVNIYGFFQSADYCSLQCPV", "length": 454, "header": "tr|A0A8V0YLB1-1|A0A8V0YLB1_CHICK Isoform 1 of Riboflavin transporter OS=Gallus gallus OX=9031 GN=SLC52A3 PE=3 SV=1 CANONICAL=A0A8V0YLB1-1" }, "locus": { "chromosome": "20", "start_pos": 10256182, "end_pos": 10254524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033080.1", "url": "https://www.ensembl.org/id/ENSGALT00010033080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019560.1", "url": "https://www.ensembl.org/id/ENSGALP00010019560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419270", "resource": "KEGG Pathway" }, { "id": "R-GGA-196843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196843", "resource": "Reactome", "description": "Vitamin B2 (riboflavin) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S866-1", "protein_name": "Riboflavin transporter", "gene_name": "SLC52A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFLTHLLVCTFGMGSWVAINGLWVELPLLVTELPEGWYLPSYLTVVIQLANIGPLLITLLHHFRPGCLSEVPIIFTVLGVGTVACTLFAFLWNVTSWVLGGHHSIAFLVLTFFLALVDCTSSVTFLPFMSRLPTHYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTETSGTTQNPETTRAMDTSQGAGSTLVSELAGTAAQVVHLESRYLPAHFSPLVFFLLLSFMMACCLVAFFFLQHQHKHWEASTEDLLASQITLQPIRPHKEKDLGPPGPEDSGKGQEPPEEKTAPCHPARLTFIYLLVAFVNALTNGVLPSVQTYSCLSYGPVAYHLSATLSSMANPLACFLSMFLPNRSLPFLGVLAVLGTGFGAYNMAMAVMSPCPLMQGHWGGEVLIVVSWVLFIGCLSYVKVMLGVILRDLSRSALLWCGAAVQLGSLLGAVVMFPLVNVFRLFSSADFCSLQCSA", "length": 469 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I8Z6-1", "protein_name": "Riboflavin transporter", "gene_name": "Slc52a3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALLTHLLVCIFGMGSWVAINGLWVELPLLVTELPEGWYLPSYLTVVIQLANIGPLLVTLLHRFQPGCLSEVPVIFLILCIGTAACVLLALLWNTTSWIQGGHHSVAFIVLTFFLALVDCTSSVTFLPFMSQLPTYYLTTFFIGEGLSGLVPALVALAQGSGITTCINATETPGTTLSPVTTVESHITQTAHSPSQSPLTWHLESRYLAPRFSPLLFFLLLSFLMGCCLVAFFILQRQPWGRQGSIEDLLHSQVTLHSIRPRDAEDASSLGAPVTSPGKGSVEVSVASLRPAQLTFIYSVVAFVNALTNGVLPSVQTYSCLPYGPVAYHLSATLSSVASPLACFLPIFLPNRSLLFLGLLTVLGTSFGAYNMAMAAMSPCPILQGHWGGEVLIVLSWVLFAACLSYVKVMLGVILRDRSRSALLWCGAAVQLGSLIGALLMFPLVNVLRLFSSADYCSLDCSV", "length": 463 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4FZU9-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 3", "gene_name": "Slc52a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFLTHLLVCVFGMGSWVAINGLWVELPLLVTKLPEGWYLPSYLTVVIQLANTGPLLVTLMHRFRPGCLSEVPVIFLILCVGTTACILLAFLWSMTSWIQGRQHSVAFIVLTFFLALVDCTSSVTFLPFMSQLPTYYLTTFFIGEGLSGLLPALVALVQGSGITTCVNVTETPGTTLNPVTTMETSITQRTLSPSLTPLTWHLESRYLAPRFSPLLFFLLLSFLMGCCLVAFFLLQRQPWGRQGSIEDLLHSQVTLHSIKPRDTEDTGSVGAPVSSPGKGSVEVSVASLRPAQLAFIYSVVAFVNALTNGVLPSVQTYSCLPYGPVAYHLSATLSSVASPLACFLPIFLPNRSLLFLGVLTVLGTGFGTYNMAMAAMSPCPILQGHWGGEVLIVLSWMLFVACLSYVKVMLGVILRDRSRSALLWCGAAVQLGSLIGALLMFPLVNVLKLFSSADYCSLDCSA", "length": 463 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E9R1-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 3", "gene_name": "SLC52A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFLIHLLVCTFGMGSWVAINGLWVELPLLVTELPEGWYLPSYLTVIIQLANVGPLLVTLLHHFRPGCLSEVAVVFTVLGVGTIACTLFAFLWNVTSWVLGSRHSIAFLVLTFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISATTLSPETTRNMDSPQGASSTLVSKLAGTAPSGIHLESRYLPANFSPLVFFLLLSFMMACCFISFFFLQRQPKRWEASIEDLLTSQVTLNSIRPQEGKDLGPPEESGKAQDPPEEKTAPQHLAHLTFIYVLVAFVNALTNGVLPSVQTYSCLSYGPVAYHLSATLSSMASPLTCFLSIFLPNRSLPFLGVLAVLGTSFGAYNMAMAVMSPCPFMQGHWGGEVLIVVSWVLFTGCLSYVKVMLGVILRDHSRSALLWCGAAVQLGSLLGAVVMFPLVNVLRLFSSADFCSLQCSA", "length": 467 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D6X5-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 3", "gene_name": "Slc52a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLTHLLVCVFGMGSWVAINGLWVELPLLVTELPEAWYLPSYLTVVIQLANIGPLLVTLMHRFRPGCLSEVPVIFLILCVGTAACILLAFLWNVTSWIQGGQHSVAFIVLTFFLALVDCTSSVTFLPFMSQLPTYYLTTFFIGEGLSGLLPALVALVQGSGITTCVNVTETPGTTLNTMETPITQGNLSPSLPSPSWHQESRYLAPRFSPLLFFLLLSFLTGCCLVAFFLLQRQPWGRQGSIEDLLHSQVTLHSIRPRDTEDTSSLGAPVSSPGKGSVEASVASLRPAQLAFIYSVVAFVNALTNGVLPSVQTYSCLPYGPVAYHLSATLSSVASPLACFLPIFLPNRSLLFLGVLTVLGTGFGAYNMAMAAMSPCPVLQGHWGGEVLIVLSWVLFAACLSYVKVMLGVILRDRSRSALLWCGAAVQLGSLIGALLMFPLVNVLKLFSSADYCSLDCSV", "length": 460 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ40-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 3", "gene_name": "SLC52A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTLLHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFVLQRQPRCWEASVEDLLNDQVTLHSIRPREENDLGPAGTVDSSQGQGYLEEKAAPCCPAHLAFIYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA", "length": 469 }, "evidence": [ { "id": "A0A8V0YLB1", "url": "https://omabrowser.org/oma/group/A0A8V0YLB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ], "pmid": "" }, { "name": "riboflavin transport", "id": "GO:0032218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "riboflavin transmembrane transporter activity", "id": "GO:0032217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "35015", "name": "", "equation": "riboflavin(in) = riboflavin(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35015" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLB5-1", "uniprot_ac": "A0A8V0YLB5", "uniprot_id": "A0A8V0YLB5_CHICK", "mass": { "chemical_mass": 130821.0, "monoisotopic_mass": 130821.0 }, "refseq": {}, "gene_names": [ { "name": "ITGA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB5" } ] } ], "protein_names": [ { "name": "Integrin subunit alpha 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB5", "locus": { "chromosome": "Z", "start_pos": 16387996, "end_pos": 16337419, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015624", "url": "https://www.ensembl.org/id/ENSGALG00010015624" } ] } } ], "crossref": [ { "id": "A0A8V0YLB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01469", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01469", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB5", "url": "https://www.orthodb.org/?gene=A0A8V0YLB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": 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On Dec 8, 2021 this sequence version replaced NP_001038146.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC693258", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YLD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "693258", "url": "https://www.ncbi.nlm.nih.gov/gene/693258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008717", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF05806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001038146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDPCFYLLLFLCLLPLPLGATSLEDPRDPLPPPLSTSDPTAHLLRGRPSAPVRPYSLSLSPEDYRYAPKPRHLRPGRLRRLLGPAFDPFWMSSEEPLGRNLSAKEDLETMSRELADSSGRYRRKLWREVEGMELPPELPADMARLLRRWLVERASCRLTSAWVDLGPVFWPRWVRHTACRTGPPACSWPPGMACRPAQLTHLKLLAWHCWAARPPGPPHCAWRQVPYPVVVACKCSCR", "length": 239, "header": "tr|A0A8V0YLD8-1|A0A8V0YLD8_CHICK Isoform 1 of Noggin OS=Gallus gallus OX=9031 GN=LOC693258 PE=1 SV=1 CANONICAL=A0A8V0YLD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8/entry", "sequence": { "sequence": "MQDPCFYLLLFLCLLPLPLGATSLEDPRDPLPPPLSTSDPTAHLLRGRPSAPVRPYSLSLSPEDYRYAPKPRHLRPGRLRRLLGPAFDPFWMSSEEPLGRNLSAKEDLETMSRELADSSGRYRRKLWREVEGMELPPELPADMARLLRRWLVERASCRLTSAWVDLGPVFWPRWVRHTACRTGPPACSWPPGMACRPAQLTHLKLLAWHCWAARPPGPPHCAWRQVPYPVVVACKCSCR", "length": 239, "header": "tr|A0A8V0YLD8-1|A0A8V0YLD8_CHICK Isoform 1 of Noggin OS=Gallus gallus OX=9031 GN=LOC693258 PE=1 SV=1 CANONICAL=A0A8V0YLD8-1" }, "locus": { "chromosome": "1", "start_pos": 51162004, "end_pos": 51161288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037665.1", "url": "https://www.ensembl.org/id/ENSGALT00010037665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021768.1", "url": "https://www.ensembl.org/id/ENSGALP00010021768.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:693258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:693258", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NWP6-1", "uniprot_ac": "A0A1D5NWP6", "uniprot_id": "A0A1D5NWP6_CHICK", "mass": { "chemical_mass": 114546.0, "monoisotopic_mass": 114546.0 }, "refseq": { "ac": "XP_004938667", "name": "RNA-binding protein 26 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938667" }, "gene_names": [ { "name": "RBM26", "type": "recommended", "evidence": [ { "id": "A0A1D5NWP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6" } ] }, { "name": "RBM26", "type": "synonym", "evidence": [ { "id": "XP_004938667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938667" } ] } ], "protein_names": [ { "name": "RNA-binding protein 26", "type": "recommended", "evidence": [ { "id": "A0A1D5NWP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 26", "type": "synonym", "evidence": [ { "id": "A0A1D5NWP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 26 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004938667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938667" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938667" } ] }, { "annotation": "May be involved in the turnover of nuclear polyadenylated (pA+) RNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X8I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I2#function" }, { "database": "UniProtKB", "id": "ARBA00043866", "url": "https://www.uniprot.org/uniprotkb/ARBA00043866#function" }, { "database": "UniProtKB", "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM26", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6", "locus": { "chromosome": "1", "start_pos": 153114030, "end_pos": 153066034, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000720", "url": "https://www.ensembl.org/id/ENSGALG00010000720" } ] } } ], "crossref": [ { "id": "A0A1D5NWP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016910", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016910", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12258", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12258", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418804", "url": "https://www.ncbi.nlm.nih.gov/gene/418804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWP6", "url": "https://www.orthodb.org/?gene=A0A1D5NWP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X8I2", "url": "https://www.orthodb.org/?gene=A0A8V0X8I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14398:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14398:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCVDQLDVFLQKETQIFVEKLFDAVNTKSYLPPTEQPSSGSLKVEFFQHQEKETKKEEIVKEEEREKKFSRRLNHSPPQSSSRYRDTRSRDERKKDERSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDRSRSRSRTRSRERDLGKPKYDMDRTDPLENNYTPVSSVTNISSGHYPVPTLSSTITVIAPAHHGNNTTESWSEFHEEQLDHNSYGRPPLPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGILPFPAQPPVVEGPPPPGLPPPPPILSPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPAGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAGVVLRLCPQETYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDAESRKRTIGAGDGGVPTKKTWFDKQNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNDHFSKFGNLVNLQVAYQGDPEGALIQFATHEEAKKAISSTEAVLNNRFIKVYWHREGSAPQIQTTAQKVIQPLVQQPSLPVVKQSVKERLGPVPASNIEPTEAQSANTEVTQNVTKLSVKDRLGFVSKPVTPATEKVLSTSTGLTKTVYNPAALKAAQKSLPVVSTSVLDSNEAQKKKQEALRLQQDVRKKKQEILEKHIETQKMLISKLEKNKAMKSEDKAEIMKTLEILTNSITKLKDELKGVSSGGGTPLKSMKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSVRGRGVHARGRGASRSRGRGIRGRGRGRGVPVHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAIHGSRFKGQELKLAWNKPVASMSAVETEEAEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "length": 1019, "header": "tr|A0A1D5NWP6-1|A0A1D5NWP6_CHICK Isoform 1 of RNA-binding protein 26 OS=Gallus gallus OX=9031 GN=RBM26 PE=1 SV=1 CANONICAL=A0A1D5NWP6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6/entry", "sequence": { "sequence": "MVVKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCVDQLDVFLQKETQIFVEKLFDAVNTKSYLPPTEQPSSGSLKVEFFQHQEKETKKEEIVKEEEREKKFSRRLNHSPPQSSSRYRDTRSRDERKKDERSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDRSRSRSRTRSRERDLGKPKYDMDRTDPLENNYTPVSSVTNISSGHYPVPTLSSTITVIAPAHHGNNTTESWSEFHEEQLDHNSYGRPPLPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGILPFPAQPPVVEGPPPPGLPPPPPILSPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPAGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAGVVLRLCPQETYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDAESRKRTIGAGDGGVPTKKTWFDKQNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNDHFSKFGNLVNLQVAYQGDPEGALIQFATHEEAKKAISSTEAVLNNRFIKVYWHREGSAPQIQTTAQKVIQPLVQQPSLPVVKQSVKERLGPVPASNIEPTEAQSANTEVTQNVTKLSVKDRLGFVSKPVTPATEKVLSTSTGLTKTVYNPAALKAAQKSLPVVSTSVLDSNEAQKKKQEALRLQQDVRKKKQEILEKHIETQKMLISKLEKNKAMKSEDKAEIMKTLEILTNSITKLKDELKGVSSGGGTPLKSMKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSVRGRGVHARGRGASRSRGRGIRGRGRGRGVPVHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAIHGSRFKGQELKLAWNKPVASMSAVETEEAEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "length": 1019, "header": "tr|A0A1D5NWP6-1|A0A1D5NWP6_CHICK Isoform 1 of RNA-binding protein 26 OS=Gallus gallus OX=9031 GN=RBM26 PE=1 SV=1 CANONICAL=A0A1D5NWP6-1" }, "locus": { "chromosome": "1", "start_pos": 153113428, "end_pos": 153066090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001541.1", "url": "https://www.ensembl.org/id/ENSGALT00010001541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000847.1", "url": "https://www.ensembl.org/id/ENSGALP00010000847.1" } ] } }, { "isoform_ac": "A0A8V0X8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I2/entry", "sequence": { "sequence": "MVVKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCVDQLDVFLQKETQIFVEKLFDAVNTKSYLPPTEQPSSGSLKVEFFQHQEKETKKEEIVKEEEREKKFSRRLNHSPPQSSSRYRDTRSRDERKKDERSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDRSRSRSRTRSRGTNSWSLKYERDLGKPKYDMDRTDPLENNYTPVSSVTNISSGHYPVPTLSSTITVIAPAHHGNNTTESWSEFHEEQLDHNSYGRPPLPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGILPFPAQPPVVEGPPPPGLPPPPPILSPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPAGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAGVVLRLCPQETYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDAESRKRTIGAGDGGVPTKKTWFDKQNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNDHFSKFGNLVNLQVAYQGDPEGALIQFATHEEAKKAISSTEAVLNNRFIKVYWHREGSAPQIQTTAQKVIQPLVQQPSLPVVKQSVKERLGPVPASNIEPTEAQSANTEVTQNVTKLSVKDRLGFVSKPVTPATEKEALRLQQDVRKKKQEILEKHIETQKMLISKLEKNKAMKSEDKAEIMKTLEILTNSITKLKDELKGVSSGGGTPLKSMKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSVRGRGVHARGRGASRSRGRGIRGRGRGRGVPVHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAIHGSRFKGQELKLAWNKPVASMSAVETEEAEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "length": 985, "header": "tr|A0A8V0X8I2-1|A0A1D5NWP6_CHICK Computationally mapped isoform of RNA-binding protein 26 OS=Gallus gallus OX=9031 GN=RBM26 PE=1 SV=1 CANONICAL=A0A1D5NWP6-1" }, "locus": { "chromosome": "1", "start_pos": 153113428, "end_pos": 153066090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001543.1", "url": "https://www.ensembl.org/id/ENSGALT00010001543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000849.1", "url": "https://www.ensembl.org/id/ENSGALP00010000849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSSPSKNTDVEQSKLLARAAPAFLKGKGLQYSLDVADRLADEHVLIGLYVNMLQSNPARVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQASCSQTDNESYVRTDDEESCFRTDDEESLAANFTEEWNQEVQRLLTKKSHN", "length": 799, "header": "tr|A0A1D5NYE9-1|A0A1D5NYE9_CHICK Isoform 1 of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=2 CANONICAL=A0A1D5NYE9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSSPSKNTDVEQSKLLARAAPAFLKGKGLQYSLDVADRLADEHVLIGLYVNMLQSNPARVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQASCSQTDNESYVRTDDEESCFRTDDEESLAANFTEEWNQEVQRLLTKKSHN", "length": 799, "header": "tr|A0A1D5NYE9-1|A0A1D5NYE9_CHICK Isoform 1 of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=2 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107203926, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012702.1", "url": "https://www.ensembl.org/id/ENSGALT00010012702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007266.1", "url": "https://www.ensembl.org/id/ENSGALP00010007266.1" } ] } }, { "isoform_ac": "A0A8V0XGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGJ7/entry", "sequence": { "sequence": "MIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSGSPFANRRLLGGINVASPVADEHSLIKLYVNQLHNNSRVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQVSLQS", "length": 716, "header": "tr|A0A8V0XGJ7-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107197665, "end_pos": 107107370, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012701.1", "url": "https://www.ensembl.org/id/ENSGALT00010012701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007265.1", "url": "https://www.ensembl.org/id/ENSGALP00010007265.1" } ] } }, { "isoform_ac": "A0A8V0XKN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKN4/entry", "sequence": { "sequence": "MHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQVSLQS", "length": 634, "header": "tr|A0A8V0XKN4-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107197665, "end_pos": 107125681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012695.1", "url": "https://www.ensembl.org/id/ENSGALT00010012695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007259.1", "url": "https://www.ensembl.org/id/ENSGALP00010007259.1" } ] } }, { "isoform_ac": "A0A8V0XN38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN38/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRRLLGGINVASPVADEHSLIKLYVNQLHNNSRVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQVSLQS", "length": 726, "header": "tr|A0A8V0XN38-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107197665, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012698.1", "url": "https://www.ensembl.org/id/ENSGALT00010012698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007262.1", "url": "https://www.ensembl.org/id/ENSGALP00010007262.1" } ] } }, { "isoform_ac": "A0A8V0XN43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN43/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQASCSQTDNESYVRTDDEESCFRTDDEESLAANFTEEWNQEVQRLLTKKSHN", "length": 742, "header": "tr|A0A8V0XN43-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107203926, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012703.1", "url": "https://www.ensembl.org/id/ENSGALT00010012703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007267.1", "url": "https://www.ensembl.org/id/ENSGALP00010007267.1" } ] } }, { "isoform_ac": "A0A8V0XQU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU0/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSSPSKNTDVEQSKLLARAAPAFLKGKGSVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQVSLQS", "length": 723, "header": "tr|A0A8V0XQU0-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107197665, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012699.1", "url": "https://www.ensembl.org/id/ENSGALT00010012699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007263.1", "url": "https://www.ensembl.org/id/ENSGALP00010007263.1" } ] } }, { "isoform_ac": "A0A8V0XQU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU4/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRSVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQASCSQTDNESYVRTDDEESCFRTDDEESLAANFTEEWNQEVQRLLTKKSHN", "length": 735, "header": "tr|A0A8V0XQU4-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107203926, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012704.1", "url": "https://www.ensembl.org/id/ENSGALT00010012704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007268.1", "url": "https://www.ensembl.org/id/ENSGALP00010007268.1" } ] } }, { "isoform_ac": "A0A8V0XT94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT94/entry", "sequence": { "sequence": "MVHTVGMIEDCGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPSIELNVARLEAVISTIFYQLNKRMPTTHQINVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGKYDLFLREVLKLPTAVFEGPSFGYTEQSAKSCFSQQKKVTLNTFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHASGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSGSPFANRRLLGGINVASPVADEHSLIKLYVNQLHNNSRSPSKNTDVEQSKLLARAAPAFLKGKGLQYSLDVADRLADEHVLIGLYVNMLQSNPARVLDSASRLDEEHKLIARYAARLAAETSSSQQQAQQRGAADISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQATQGAGSPRSSPSHTISRPIPMPIRSASACSTPTHTPQDSLTGVGGDVQEAFAQSARRNLRNDLLVAADSITNTMSSLVKELNSEVGSETESNVDSEFGRTHFDDLVPSPTSEKAFLAQIHARKPGYIHSAAATGSMRSDMVTEDGDPFVRADDENYENDSVRQLENELKMEEYLKQKLQDEAYQVSLQS", "length": 783, "header": "tr|A0A8V0XT94-1|A0A1D5NYE9_CHICK Computationally mapped isoform of Dystrobrevin alpha OS=Gallus gallus OX=9031 GN=DTNA PE=1 SV=1 CANONICAL=A0A1D5NYE9-1" }, "locus": { "chromosome": "2", "start_pos": 107197665, "end_pos": 107029773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012697.1", "url": "https://www.ensembl.org/id/ENSGALT00010012697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007261.1", "url": "https://www.ensembl.org/id/ENSGALP00010007261.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 507, "start_aa": "Thr", "end_pos": 507, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr507", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYE9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 799, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYE9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYE9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 507 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 349, "end_pos": 351 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 756, "end_pos": 758 }, { "start_pos": 780, "end_pos": 782 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQZ2-1", "uniprot_ac": "A0A8V0YQZ2", "uniprot_id": "A0A8V0YQZ2_CHICK", "mass": { "chemical_mass": 40772.0, "monoisotopic_mass": 40772.0 }, "refseq": {}, "gene_names": [ { "name": "HRH2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ] } ], "protein_names": [ { "name": "Histamine H2 receptor", "type": "recommended", "evidence": [ { "id": "A0A8V0YQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2/entry#names_and_taxonomy" } ] }, { "name": "Gastric receptor I", "type": "synonym", "evidence": [ { "id": "A0A8V0YQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "G-protein coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels. This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology. Also expressed in other tissues, including the heart and central nervous system, where it may contribute to cardiac stimulation and modulate neurotransmitter release.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUM1#function" }, { "database": "UniProtKB", "id": "ARBA00094527", "url": "https://www.uniprot.org/uniprotkb/ARBA00094527#function" }, { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2#function" }, { "database": "UniProtKB", "id": "F1NUQ9", "url": "https://www.uniprot.org/uniprotkb/F1NUQ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2", "locus": { "chromosome": "13", "start_pos": 10067849, "end_pos": 10079205, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014576", "url": "https://www.ensembl.org/id/ENSGALG00010014576" } ] } } ], "crossref": [ { "id": "A0A8V0YQZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024171", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000024171", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427635", "url": "https://www.ncbi.nlm.nih.gov/gene/427635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427635", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427635", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGNVMVC", "url": "https://omabrowser.org/oma/group/CGNVMVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TUM1", "url": "https://www.orthodb.org/?gene=A0A3Q2TUM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQZ2", "url": "https://www.orthodb.org/?gene=A0A8V0YQZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NUQ9", "url": "https://www.orthodb.org/?gene=F1NUQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247:SF278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247:SF278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390650", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390650", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TUM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUQ9", "url": "https://www.uniprot.org/uniprotkb/F1NUQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUQ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NUQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPCSNLTDPSKTMDFPLQLLVGSCLALLITFTLCGNIIVCLAVTLDRRLRSLTNCIIVSLAITDLLLALLVLPFSAYYELTSEWPFSSTLCNIYLSLDVMLCTASILNLFIISLDRYFAVTTPLRYQQLVTRSRVAVGLVVIWTVSLMVSFLPIHLGWNTNGTMVQNTTPNCTRECKLEVNSVYGLVDSLLTFYIPLVIMCITYYRIFKIAREQAKRINHTWCCSSNGPMPPMVKEHKATVTLAVVMGAFIICWFPYFTVFTYRGVWGDSSVKGIPMSIVLWLGYANSALNPILYGTFNRDFRVAYQHLLQCWRTGDPKSSLQKGQPRGRSCGESLDGQEGKCLKLEMRNGKGTLLADGALQR", "length": 364, "header": "tr|A0A8V0YQZ2-1|A0A8V0YQZ2_CHICK Isoform 1 of Histamine H2 receptor OS=Gallus gallus OX=9031 GN=HRH2 PE=3 SV=1 CANONICAL=A0A8V0YQZ2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUM1/entry", "sequence": { "sequence": "MDPCSNLTDPSKTMDFPLQLLVGSCLALLITFTLCGNIIVCLAVTLDRRLRSLTNCIIVSLAITDLLLALLVLPFSAYYELTSEWPFSSTLCNIYLSLDVMLCTASILNLFIISLDRYFAVTTPLRYQQLVTRSRVAVGLVVIWTVSLMVSFLPIHLGWNTNGTMVQNTTPNCTRECKLEVNSVYGLVDSLLTFYIPLVIMCITYYRIFKIAREQAKRINHTWCCSSNGPMPPMVKEHKATVTLAVVMGAFIICWFPYFTVFTYRGVWGDSSVKGIPMSIVLWLGYANSALNPILYGTFNRDFRVAYQHLLQCWRTGDPKSSLQKGQPRGRSCGESLDGQEGKCLKLEMRNGKGTLLADGALQSDGAFP", "length": 369, "header": "tr|A0A3Q2TUM1-1|A0A8V0YQZ2_CHICK Computationally mapped isoform of Histamine H2 receptor OS=Gallus gallus OX=9031 GN=HRH2 PE=3 SV=1 CANONICAL=A0A8V0YQZ2-1" }, "locus": { "chromosome": "13", "start_pos": 10074488, "end_pos": 10071417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034992.1", "url": "https://www.ensembl.org/id/ENSGALT00010034992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020451.1", "url": "https://www.ensembl.org/id/ENSGALP00010020451.1" } ] } }, { "isoform_ac": "A0A8V0YQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2/entry", "sequence": { "sequence": "MDPCSNLTDPSKTMDFPLQLLVGSCLALLITFTLCGNIIVCLAVTLDRRLRSLTNCIIVSLAITDLLLALLVLPFSAYYELTSEWPFSSTLCNIYLSLDVMLCTASILNLFIISLDRYFAVTTPLRYQQLVTRSRVAVGLVVIWTVSLMVSFLPIHLGWNTNGTMVQNTTPNCTRECKLEVNSVYGLVDSLLTFYIPLVIMCITYYRIFKIAREQAKRINHTWCCSSNGPMPPMVKEHKATVTLAVVMGAFIICWFPYFTVFTYRGVWGDSSVKGIPMSIVLWLGYANSALNPILYGTFNRDFRVAYQHLLQCWRTGDPKSSLQKGQPRGRSCGESLDGQEGKCLKLEMRNGKGTLLADGALQR", "length": 364, "header": "tr|A0A8V0YQZ2-1|A0A8V0YQZ2_CHICK Isoform 1 of Histamine H2 receptor OS=Gallus gallus OX=9031 GN=HRH2 PE=3 SV=1 CANONICAL=A0A8V0YQZ2-1" }, "locus": { "chromosome": "13", "start_pos": 10074488, "end_pos": 10073397, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035001.1", "url": "https://www.ensembl.org/id/ENSGALT00010035001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020455.1", "url": "https://www.ensembl.org/id/ENSGALP00010020455.1" } ] } }, { "isoform_ac": "F1NUQ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NUQ9/entry", "sequence": { "sequence": "MDPCSNLTDPSKTMDFPLQLLVGSCLALLITFTLCGNIIVCLAVTLDRRLRSLTNCIIVSLAITDLLLALLVLPFSAYYELTSEWPFSSTLCNIYLSLDVMLCTASILNLFIISLDRYFAVTTPLRYQQLVTRSRVAVGLVVIWTVSLMVSFLPIHLGWNTNGTMVQNTTPNCTRECKLEVNSVYGLVDSLLTFYIPLVIMCITYYRIFKIAREQAKRINHTWCCSSNGPMPPMVKEHKATVTLAVVMGAFIICWFPYFTVFTYRGVWGDSSVKGIPMSIVLWLGYANSALNPILYGTFNRDFRVAYQHLLQCWRTGDPKSSLQKGQPRGRSCGESLDGQEGKCLKLEMRNGKGTLLADGALQRIPVLVPGTCCLPR", "length": 377, "header": "tr|F1NUQ9-1|A0A8V0YQZ2_CHICK Computationally mapped isoform of Histamine H2 receptor OS=Gallus gallus OX=9031 GN=HRH2 PE=3 SV=3 CANONICAL=A0A8V0YQZ2-1" }, "locus": { "chromosome": "13", "start_pos": 10074488, "end_pos": 10069699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034979.1", "url": "https://www.ensembl.org/id/ENSGALT00010034979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020446.1", "url": "https://www.ensembl.org/id/ENSGALP00010020446.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427635", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427635", "resource": "KEGG Pathway" }, { "id": "R-GGA-390650", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390650", "resource": "Reactome", "description": "Histamine receptors" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q9U8-1", "protein_name": "Histamine H2 receptor", "gene_name": "hrh2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSQIALAVTLSVLILLTVSGNILVCLAVYATRRLRNVTNCFIVSLAVTDFLLGALVLPFSTLYQVTGDWPLGAHFCNIYISLDVMLCTASILNLFAISLDRYFAVTAPLRYPMLVLPWRVGAILATIWLVSVGVSFVPIHLGWNTRDLSVQNIREGDHARDCRFELNPTYAIVDAFSTFYLPLLAMCWSYHRVFRIARMRAKRIISTRRGSTSSQGVTILTLREHKATVTLAVVLGAFVVCWFPYFTFFTIMGIRNEENPPQTAQSVVLWLGYANSALNPVLYATLNRDFRSAYAKLLCGGRRCKTETTIPIAATAAGTMTGHAHSSKGAGFLPRTCVLLKDSENRMLDDNSATNGATVTVVANGSKR", "length": 369 }, "evidence": [ { "id": "A0A8V0YQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9S2V5-1", "protein_name": "Histamine H2 receptor", "gene_name": "HRH2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAANGTASSSCLDPTAFKVTVTVVLILLILITIAGNVVVCLAVGLNRRLRSLTNCFIVSLAITDLLLGLLVLPFSAFYQLSCQWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAVSLVLIWVISITLSFLSIHLEWNSRPENHSDSHTIPKCKVQVNLVYGLVDGLVTFYLPLLVMCITYYRIFRIAREQARRIHNVGPWRAATLREHKATVTLAAVMGAFIVCWLPYFTVFVYRGLRGDSAVDKTVEDVVLWLGYANSALNPVLYAALNRDFRTAYQQLFRCSPAGQDARRTSLGSNSSQLVRHPGQGPRWPEERPLRLQVWSGTELTAPQGATDR", "length": 359 }, "evidence": [ { "id": "A0A8V0YQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P25021-1", "protein_name": "Histamine H2 receptor", "gene_name": "HRH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR", "length": 359 }, "evidence": [ { "id": "A0A8V0YQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25102-1", "protein_name": "Histamine H2 receptor", "gene_name": "Hrh2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR", "length": 358 }, "evidence": [ { "id": "A0A8V0YQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97292-1", "protein_name": "Histamine H2 receptor", "gene_name": "Hrh2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQLFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTRLSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA", "length": 397 }, "evidence": [ { "id": "A0A8V0YQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "positive regulation of vasoconstriction", "id": "GO:0045907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045907", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "gastric acid secretion", "id": "GO:0001696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001696", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neurotransmitter receptor activity", "id": "GO:0030594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" }, { "name": "histamine receptor activity", "id": "GO:0004969", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004969", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 296, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NV13-1", "uniprot_ac": "A0A1D5NV13", "uniprot_id": "A0A1D5NV13_CHICK", "mass": { "chemical_mass": 24886.0, "monoisotopic_mass": 24886.0 }, "refseq": { "ac": "XP_001233997", "name": "GTP-binding protein Rit2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997" }, "gene_names": [ { "name": "RIT2", "type": "recommended", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "name": "RIT2", "type": "synonym", "evidence": [ { "id": "XP_001233997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein Rit2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233997.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13", "locus": { "chromosome": "Z", "start_pos": 3994584, "end_pos": 3807386, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012204", "url": "https://www.ensembl.org/id/ENSGALG00010012204" } ] } } ], "crossref": [ { "id": "A0A1D5NV13", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NV13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033353", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033353", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770660", "url": "https://www.ncbi.nlm.nih.gov/gene/770660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRRKQRH", "url": "https://omabrowser.org/oma/group/FRRKQRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NV13", "url": "https://www.orthodb.org/?gene=A0A1D5NV13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8G0", "url": "https://www.orthodb.org/?gene=A0A8V0Y8G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDG9", "url": "https://www.orthodb.org/?gene=A0A8V0YDG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEN6", "url": "https://www.orthodb.org/?gene=A0A8V0YEN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGT3", "url": "https://www.orthodb.org/?gene=A0A8V0YGT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233997", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELENEMISSSSNSSAGSREYKVVMLGAGGVGKSAMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQVSTEEGMSLARAYSCSFFETSAALRFYIDDVFHGLVREIRRKESSLTVAEKKMKRKDSLWRKLKGSLRKKKESTT", "length": 217, "header": "tr|A0A1D5NV13-1|A0A1D5NV13_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13/entry", "sequence": { "sequence": "MELENEMISSSSNSSAGSREYKVVMLGAGGVGKSAMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQVSTEEGMSLARAYSCSFFETSAALRFYIDDVFHGLVREIRRKESSLTVAEKKMKRKDSLWRKLKGSLRKKKESTT", "length": 217, "header": "tr|A0A1D5NV13-1|A0A1D5NV13_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "locus": { "chromosome": "Z", "start_pos": 3993224, "end_pos": 3807557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029276.1", "url": "https://www.ensembl.org/id/ENSGALT00010029276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016993.1", "url": "https://www.ensembl.org/id/ENSGALP00010016993.1" } ] } }, { "isoform_ac": "A0A8V0Y8G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8G0/entry", "sequence": { "sequence": "MLLLRCFFPWNELALSLLESLFHTMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQVSTEEGMSLARAYSCSFFETSAALRFYIDDVFHGLVREIRRKESSLTVAEKKMKRKDSLWRKLKGSLRKKKESTT", "length": 206, "header": "tr|A0A8V0Y8G0-1|A0A1D5NV13_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "locus": { "chromosome": "Z", "start_pos": 3993224, "end_pos": 3856595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029265.1", "url": "https://www.ensembl.org/id/ENSGALT00010029265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016983.1", "url": "https://www.ensembl.org/id/ENSGALP00010016983.1" } ] } }, { "isoform_ac": "A0A8V0YDG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDG9/entry", "sequence": { "sequence": "MELENEMISSSSNSSAGSREYKVVMLGAGGVGKSAMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQSTLGAFRKYKIAAQKKLKKRKRKRKTKKRKKKKRKKKKKTYNFLLIIFEVLGNVILPLSL", "length": 202, "header": "tr|A0A8V0YDG9-1|A0A1D5NV13_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "locus": { "chromosome": "Z", "start_pos": 3959084, "end_pos": 3807557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029269.1", "url": "https://www.ensembl.org/id/ENSGALT00010029269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016987.1", "url": "https://www.ensembl.org/id/ENSGALP00010016987.1" } ] } }, { "isoform_ac": "A0A8V0YEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN6/entry", "sequence": { "sequence": "MLKDFLVHHPHGKRAMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQVSTEEGMSLARAYSCSFFETSAALRFYIDDVFHGLVREIRRKESSLTVAEKKMKRKDSLWRKLKGSLRKKKESTT", "length": 197, "header": "tr|A0A8V0YEN6-1|A0A1D5NV13_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "locus": { "chromosome": "Z", "start_pos": 3993224, "end_pos": 3861277, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029262.1", "url": "https://www.ensembl.org/id/ENSGALT00010029262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016980.1", "url": "https://www.ensembl.org/id/ENSGALP00010016980.1" } ] } }, { "isoform_ac": "A0A8V0YGT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT3/entry", "sequence": { "sequence": "MELENEMISSSSNSSAGSREYKVVMLGAGGVGKSAMTMQFISHRFPDYHDPTIEDAYKTQVRIDDEPAYLDILDTAGQAEFTAMRDQYMRGGEGFIICYSITDRQSFQEAAEFKELIYRVRHTYDIPLVLVGNKTDLEEFRQIFLYFCLTDIFFVCLFYIYVVCLFIYLFIFQEKLESWREMFLSKSNTLDKNSSILTSHIITLFKLLSHDIQKIFKIQKCLIHTNPLKKTERLRQREREEKISALYLFQKHSIPFQ", "length": 257, "header": "tr|A0A8V0YGT3-1|A0A1D5NV13_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RIT2 PE=3 SV=1 CANONICAL=A0A1D5NV13-1" }, "locus": { "chromosome": "Z", "start_pos": 3915892, "end_pos": 3807557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029258.1", "url": "https://www.ensembl.org/id/ENSGALT00010029258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016976.1", "url": "https://www.ensembl.org/id/ENSGALP00010016976.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770660", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P70425-1", "protein_name": "GTP-binding protein Rit2", "gene_name": "Rit2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVENEAHCCPGSSSGGSREYKVVMLGAGGVGKSAVTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQFRQVSTEEGMNLARDYNCAFFETSAALRFGIDDAFQGLVREIRRKESMLSLVERKLKRKDSLWKKIKASLKKKRENML", "length": 217 }, "evidence": [ { "id": "A0A1D5NV13", "url": "https://omabrowser.org/oma/group/A0A1D5NV13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BJQ5-1", "protein_name": "GTP-binding protein Rit2", "gene_name": "Rit2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAENEAHCCPGSSSGGSREYKVVMLGAGGVGKSAVTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQFRQVSTEEGMTLARDYNCAFFETSAALRFGIDDAFQGLVREIRRKESMLSLVERKLKRKDSLWKKIKASLKKKRENMI", "length": 217 }, "evidence": [ { "id": "A0A1D5NV13", "url": "https://omabrowser.org/oma/group/A0A1D5NV13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99578-1", "protein_name": "GTP-binding protein Rit2", "gene_name": "RIT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVENEASCSPGSASGGSREYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPSLMEKKLKRKDSLWKKLKGSLKKKRENMT", "length": 217 }, "evidence": [ { "id": "A0A1D5NV13", "url": "https://omabrowser.org/oma/group/A0A1D5NV13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "dendritic tree", "id": "GO:0097447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097447", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "maintenance of protein location in cell", "id": "GO:0032507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032507", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" }, { "name": "regulation of Cdc42 protein signal transduction", "id": "GO:0032489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032489", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": 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phosphate + H(+).", "evidence": [ { "id": "Q5ZIT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5ZIT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT5" } ] } ] }, { "uniprot_ac": "Q5ZJD3", "gene_name": "LSG1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5ZJD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD3" } ] } ] }, { "uniprot_ac": "Q5ZJN2", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5ZJN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5ZJN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN2" } ] } ] }, { "uniprot_ac": "Q5ZKR4", "gene_name": "RABL3", "activity": [ { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YM44-1", "uniprot_ac": "A0A8V0YM44", "uniprot_id": "A0A8V0YM44_CHICK", "mass": { "chemical_mass": 30947.0, "monoisotopic_mass": 30947.0 }, "refseq": {}, "gene_names": [ { "name": "PSMG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YM44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ] } ], "protein_names": [ { "name": "Proteasome assembly chaperone 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YM44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44#function" }, { "database": "UniProtKB", "id": "PIRNR010076", "url": "https://www.uniprot.org/uniprotkb/PIRNR010076#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44", "locus": { "chromosome": "1", "start_pos": 108007292, "end_pos": 108022574, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013375", "url": "https://www.ensembl.org/id/ENSGALG00010013375" } ] } } ], "crossref": [ { "id": "A0A8V0YM44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM44", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR016565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDV1", "url": "https://www.orthodb.org/?gene=A0A8V0YDV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDV6", "url": "https://www.orthodb.org/?gene=A0A8V0YDV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM44", "url": "https://www.orthodb.org/?gene=A0A8V0YM44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15069:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15069:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9907900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATFFGEVVVAPSRAGVDDEEETEETAEDREIRRELEITVLWTPGAAGSPAEEPLRCSRFIVAVGHNAVAFLSAFILDSVCWNIVGAVKLWNEWCQTTNATSVLPTDSFCLFYQLISDPTVLLCQCSCYVAEDQQFQWLEKVFGHIGKKGLQVTILSTCPVAEYKTQESTLTLPSPFLKALKTKEFKEEVCCPLLEQPNIVRDLPAAVLSYCQVWQIPAVLYQCYTDIIKLDAVTIEAFKPLLSSKPLKNLVKDISESTKILKKLLTTGETHNNIYI", "length": 277, "header": "tr|A0A8V0YM44-1|A0A8V0YM44_CHICK Isoform 1 of Proteasome assembly chaperone 1 OS=Gallus gallus OX=9031 GN=PSMG1 PE=1 SV=1 CANONICAL=A0A8V0YM44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV1/entry", "sequence": { "sequence": "MVPAQQSGSARVRDARPLGRGRREAAAAGRWRRSSERLWSLRPGPAWTMRRRPRRRPRIGRSAGSCRRKAFLSAFILDSVCWNIVGAVKLWNEWCQTTNATSVLPTDSFCLFYQLISDPTVLLCQCSCYVAEDQQFQWLEKVFGHIGKKGLQVTILSTCPVAEYKTQESTLTLPSPFLKALKTKEFKEEVCCPLLEQPNIVRDLPAAVLSYCQVWQIPAVLYQCYTDIIKLDAVTIEAFKPLLSSKPLKNLVKDISESTKILKKLLTTGETHNNIYI", "length": 277, "header": "tr|A0A8V0YDV1-1|A0A8V0YM44_CHICK Computationally mapped isoform of Proteasome assembly chaperone 1 OS=Gallus gallus OX=9031 GN=PSMG1 PE=1 SV=1 CANONICAL=A0A8V0YM44-1" }, "locus": { "chromosome": "1", "start_pos": 108022375, "end_pos": 108014940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032206.1", "url": "https://www.ensembl.org/id/ENSGALT00010032206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018996.1", "url": "https://www.ensembl.org/id/ENSGALP00010018996.1" } ] } }, { "isoform_ac": "A0A8V0YDV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV6/entry", "sequence": { "sequence": "MATFFGEVVVAPSRAGVDDEEETEETAEDREIRRELQEKREITVLWTPGAAGSPAEEPLRCSRFIVAVGHNAVAFLSAFILDSVCWNIVGAVKLWNEWCQTTNATSVLPTDSFCLFYQLISDPTVLLCQCSCYVAEDQQFQWLEKVFGHIGKKGLQVTILSTCPVAEYKTQESTLTLPSPFLKALKTKEFKEEVCCPLLEQPNIVRDLPAAVLSYCQVWQIPAVLYQCYTDIIKLDAVTIEAFKPLLSSKPLKNLVKVFGGLRCL", "length": 265, "header": "tr|A0A8V0YDV6-1|A0A8V0YM44_CHICK Computationally mapped isoform of Proteasome assembly chaperone 1 OS=Gallus gallus OX=9031 GN=PSMG1 PE=1 SV=1 CANONICAL=A0A8V0YM44-1" }, "locus": { "chromosome": "1", "start_pos": 108022286, "end_pos": 108007371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032211.1", "url": "https://www.ensembl.org/id/ENSGALT00010032211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019001.1", "url": "https://www.ensembl.org/id/ENSGALP00010019001.1" } ] } }, { "isoform_ac": "A0A8V0YM44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44/entry", "sequence": { "sequence": "MATFFGEVVVAPSRAGVDDEEETEETAEDREIRRELEITVLWTPGAAGSPAEEPLRCSRFIVAVGHNAVAFLSAFILDSVCWNIVGAVKLWNEWCQTTNATSVLPTDSFCLFYQLISDPTVLLCQCSCYVAEDQQFQWLEKVFGHIGKKGLQVTILSTCPVAEYKTQESTLTLPSPFLKALKTKEFKEEVCCPLLEQPNIVRDLPAAVLSYCQVWQIPAVLYQCYTDIIKLDAVTIEAFKPLLSSKPLKNLVKDISESTKILKKLLTTGETHNNIYI", "length": 277, "header": "tr|A0A8V0YM44-1|A0A8V0YM44_CHICK Isoform 1 of Proteasome assembly chaperone 1 OS=Gallus gallus OX=9031 GN=PSMG1 PE=1 SV=1 CANONICAL=A0A8V0YM44-1" }, "locus": { "chromosome": "1", "start_pos": 108022286, "end_pos": 108014940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032199.1", "url": "https://www.ensembl.org/id/ENSGALT00010032199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018989.1", "url": "https://www.ensembl.org/id/ENSGALP00010018989.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "protein folding chaperone complex", "id": "GO:0101031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteasome core complex assembly", "id": "GO:0080129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" }, { "name": "proteasome assembly", "id": "GO:0043248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043248", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P482-1", "uniprot_ac": "A0A1D5P482", "uniprot_id": "A0A1D5P482_CHICK", "mass": { "chemical_mass": 112944.0, "monoisotopic_mass": 112944.0 }, "refseq": { "ac": "NP_001035318", "name": "integrator complex subunit 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035318" }, "gene_names": [ { "name": "INTS8", "type": "recommended", "evidence": [ { "id": "A0A1D5P482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ] }, { "name": "INTS8", "type": "synonym", "evidence": [ { "id": "NP_001035318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035318" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 8", "type": "synonym", "evidence": [ { "id": "A0A1D5P482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 8", "type": "synonym", "evidence": [ { "id": "NP_001035318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035318" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.27349.1, SRR13267656.2729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On May 4, 2006 this sequence version replaced XP_418341.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001035318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035318" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482", "locus": { "chromosome": "2", "start_pos": 125964319, "end_pos": 125939315, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012366", "url": "https://www.ensembl.org/id/ENSGALG00010012366" } ] } } ], "crossref": [ { "id": "A0A1D5P482", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P482", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037955", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037955", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420230", "url": "https://www.ncbi.nlm.nih.gov/gene/420230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420230", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASLSDWM", "url": "https://omabrowser.org/oma/group/ASLSDWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P482", "url": "https://www.orthodb.org/?gene=A0A1D5P482", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFE2", "url": "https://www.orthodb.org/?gene=A0A8V0YFE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHI6", "url": "https://www.orthodb.org/?gene=A0A8V0YHI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMA9", "url": "https://www.orthodb.org/?gene=A0A8V0YMA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13350:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13350:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001035318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035318", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P482-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKWEVPNVYGNVILGIKDNLTRDLVYILMAKGLHCCAIKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVIKRMIKCCSLLNCHTQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995, "header": "tr|A0A1D5P482-1|A0A1D5P482_CHICK Isoform 1 of Integrator complex subunit 8 OS=Gallus gallus OX=9031 GN=INTS8 PE=1 SV=1 CANONICAL=A0A1D5P482-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P482-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482/entry", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKWEVPNVYGNVILGIKDNLTRDLVYILMAKGLHCCAIKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVIKRMIKCCSLLNCHTQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995, "header": "tr|A0A1D5P482-1|A0A1D5P482_CHICK Isoform 1 of Integrator complex subunit 8 OS=Gallus gallus OX=9031 GN=INTS8 PE=1 SV=1 CANONICAL=A0A1D5P482-1" }, "locus": { "chromosome": "2", "start_pos": 125964142, "end_pos": 125939423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029633.1", "url": "https://www.ensembl.org/id/ENSGALT00010029633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017242.1", "url": "https://www.ensembl.org/id/ENSGALP00010017242.1" } ] } }, { "isoform_ac": "A0A8V0YFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE2/entry", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKWEVPNVYGNVILGIKDNLTRDLVYILMAKGLHCCAIKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVIKRMIKCCSLLNCHTQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAVSSGSALGVSRSAAFLPWGSPLTQWSLSALIVFHSLDAGWSASSHGGGAEGIGCWGSIHTSLILLTGSETVTEQLCTITVATAVSFVR", "length": 1045, "header": "tr|A0A8V0YFE2-1|A0A1D5P482_CHICK Computationally mapped isoform of Integrator complex subunit 8 OS=Gallus gallus OX=9031 GN=INTS8 PE=1 SV=1 CANONICAL=A0A1D5P482-1" }, "locus": { "chromosome": "2", "start_pos": 125964029, "end_pos": 125939423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029618.1", "url": "https://www.ensembl.org/id/ENSGALT00010029618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017232.1", "url": "https://www.ensembl.org/id/ENSGALP00010017232.1" } ] } }, { "isoform_ac": "A0A8V0YHI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI6/entry", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVIKRMIKCCSLLNCHTQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 958, "header": "tr|A0A8V0YHI6-1|A0A1D5P482_CHICK Computationally mapped isoform of Integrator complex subunit 8 OS=Gallus gallus OX=9031 GN=INTS8 PE=1 SV=1 CANONICAL=A0A1D5P482-1" }, "locus": { "chromosome": "2", "start_pos": 125964142, "end_pos": 125939423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029628.1", "url": "https://www.ensembl.org/id/ENSGALT00010029628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017238.1", "url": "https://www.ensembl.org/id/ENSGALP00010017238.1" } ] } }, { "isoform_ac": "A0A8V0YMA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA9/entry", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKWEVPNVYGNVILGIKDNLTRDLVYILMAKGLHCCAIKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 978, "header": "tr|A0A8V0YMA9-1|A0A1D5P482_CHICK Computationally mapped isoform of Integrator complex subunit 8 OS=Gallus gallus OX=9031 GN=INTS8 PE=1 SV=1 CANONICAL=A0A1D5P482-1" }, "locus": { "chromosome": "2", "start_pos": 125964142, "end_pos": 125939423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029624.1", "url": "https://www.ensembl.org/id/ENSGALT00010029624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017236.1", "url": "https://www.ensembl.org/id/ENSGALP00010017236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420230", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A1ZAK1-1", "protein_name": "Integrator complex subunit 8", "gene_name": "IntS8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDPLKPKPVPLAAETVLWFEFLLDPHKITQHLQRPHPEPSAMELIVQFISMTPNTAQESVGTPGSDLQNLNQTPSNSGPIPGVVGGAPAPTTPTASGGVGMPHSPQRPAEKGLQLNRKQLALKILELKVATWLKWDLDALEKNLPVIMQLALLRDLCTISYGCSLSIPLPNDFDARISAAGNERAARFALTIYHRMLLRMQLIKEQALKAPRPQNTMYQTVDQLQQFLDTPTQPSIEYLQQLCASTKPFYIFHYDSFVPLRCDDIGNGQNYDVMHLITPQELRAQLHYELAQYYLYTKQYVLAREAAAACNTNLQAIPPQTTLYYCHIRPSELEGLLQACGISAEEQSLLEKFQQSLLNNYTDIVSILRMDNRRREIPFISRRQVELDIEGSISTGILKETVQLQLQVAALNVVRNIFEWGSIFGSVEYFEKYRELDCLPPLVEALQEMLPHCTFKEQAALKHFLIDCLLHQGGQSRQLLQTVRGFGLFSSDELQDIDEQMLQATPPVPTNSLASLSDWMCHSKMSRVDVGALERQLISCTNANTVRILLVKLCATAPGKPLWAINPSWDVPQPLKTLIMAMPVSFLQDFSYVLLGKARELATRGNYIDAVSMLSVLKSENQRQEMAANVQLMCKLITWEILHIQITQCLEEWHQKPLDLQSLGGRCKQCLGALQAGDSIVPRPDILESCAIMLLNLTEFPPLLYLDKRAGPLELPLAFAATFIEMEKMKGPKKVCRDAWELMLSMFLNVPKRGSSGVGGISSLQAFLQRIRHQSVFGLAISMIGKVHNILKDDPNHDLSCEYMQLWPTSINNPVSYSLRSVCETLQWLLSEALSYYPQTISWLKMKGDLDLAIGNNESAMRCYVNALVTGTDYCTMPLQRNVADDYVIRKMIRCAANLGCHMQATVLCQFLDEIDYGIVFKNLSEKSSNFTDAMDAYYSCIWDTTLLEFIVNLHAKRGEHSRKLEAISMMGTLELNANNNEEIKRESAMVRKSRFLRALAKQYLL", "length": 1007 }, "evidence": [ { "id": "A0A1D5P482", "url": "https://omabrowser.org/oma/group/A0A1D5P482/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A3KQN9-1", "protein_name": "Integrator complex subunit 8", "gene_name": "ints8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAEAADREAVSGSRPCTPPQTSWFEFLLNPSLLEQHLHSPHPDPSPVQLIFQFLEQASKPSVNEQNQVQPPVDNRRNRTLKLMALKVAAHLRWDLNMLEKGLTIPVLNMLLNELLCVSHVPPGVKHVDLDLSSLPPTTAMAVVFYNRWAIRTIVLSSFPEKQTKPGPHQLNMMNMLQQEKEHTENILSVLREQATDSIVVLEGALSIKKDFYIHTLRTLDLLAADPSTTNGETEYSTAGLRISFDHLHCQVHYDLGGIYFQQGCSDTSVYEKAREHFRKARELLTKLDFSASFCCLDEQRLAGYWSACRTLTGTSDLNESQHTPYGQISCFMRNHNYGALIEEFICDNVTLSLPNSFRHSIQLELMHKLQQGDSALEEVCNKLCVCNAVRDALEGGILSVSFHQLLLKPSKNIISFLLEVCTRSLEKENLPELSKSKMALFIKTVCDQLGDVSLAFMVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 996 }, "evidence": [ { "id": "A0A1D5P482", "url": "https://omabrowser.org/oma/group/A0A1D5P482/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZLQ6-1", "protein_name": "Integrator complex subunit 8", "gene_name": "Ints8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKACPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRSLKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCVSKVPPGTKHVDVDLAALPPTTAMAILLYNRWAIRTIVQSSFPVKQAKPGPPQLNVMNQMQQEKELTENILKVLREQAADSILVLEAALKLNKDLYVHTMRTLDLLAVEPGTVNGETENSTAGLKIRTEEMQCQVCYDLGAAYFQQGSTNSAAYESAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDTNSQQVTPYSQVHICLRSGSYQEVVQIFIEDNVTFTLPVQFRQSVLRELFQKAQQGNEALDEICFKICSCNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSIDIEKASDSLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSTVILGIKDNLTRDLVYILMAKGLHCSTVKDFPHSKQLFTAGLELVTEFSPKLRQVMLNEILLLDILTHEAGVGHSGERPPSDLISRVRGYLEMRLPDIPLRQVVAAECVAFMLNWRENEYLTLQVPAFLFQNNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVREVVRYALSVNPNSHAWLIIQADIYFATNQHSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 978 }, "evidence": [ { "id": "A0A1D5P482", "url": "https://omabrowser.org/oma/group/A0A1D5P482/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q75QN2-1", "protein_name": "Integrator complex subunit 8", "gene_name": "INTS8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995 }, "evidence": [ { "id": "A0A1D5P482", "url": "https://omabrowser.org/oma/group/A0A1D5P482/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80V86-1", "protein_name": "Integrator complex subunit 8", "gene_name": "Ints8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKACPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRVLKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLSALPPTTAMAILLYNRWAIRTIVQSSFPVKQAKPGPPQLNVMNQMQQEKELTENILKVLKEQAADCILVLEAALRLNKDLYVHTMRTLDLLAVEPGTVNGETENSTAGLKIRTEEMQCQVCYDLGAAYFQQGSTDSAIYENAREKFFRTKELLAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDNNSQQLTPYSQVHICLRSGSYQEVVQIFIEDNLTFTLPVQFRQSVLRELFQKAQQGNEALDEICFKICVCNTVRDVLEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSINVEKASDSLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSSVILGIKDNLTRDLVYILMAKGLHCSTVKDFPHSKQLFTACLELVTEFSPKLRQVMLNEMLLLDIRTHEAGVGQSGERPPSDLISRVRGYLEMRLPDIPLRQVVAEECVAFMLNWRENEYLTLQVPAFLFQNNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHAWLIIQADIYFATNQHSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995 }, "evidence": [ { "id": "A0A1D5P482", "url": "https://omabrowser.org/oma/group/A0A1D5P482/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P482", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P482" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P2P6-1", "uniprot_ac": "A0A1D5P2P6", "uniprot_id": "A0A1D5P2P6_CHICK", "mass": { "chemical_mass": 197532.0, "monoisotopic_mass": 197532.0 }, "refseq": { "ac": "XP_416046", "name": "AT-rich interactive domain-containing protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416046" }, "gene_names": [ { "name": "ARID2", "type": "recommended", "evidence": [ { "id": "A0A1D5P2P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P6" } ] }, { "name": "ARID2", "type": "synonym", "evidence": [ { "id": "XP_416046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416046" } ] } ], "protein_names": [ { "name": "AT-rich interaction domain 2", "type": "synonym", "evidence": [ { "id": "A0A1D5P2P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P6/entry#names_and_taxonomy" } ] }, { "name": "AT-rich interactive domain-containing protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_416046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416046" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_416046.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416046" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2P6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARID2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P6", "locus": { "chromosome": "1", "start_pos": 30999136, "end_pos": 30891553, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013878", "url": "https://www.ensembl.org/id/ENSGALG00010013878" } ] } } ], "crossref": [ { "id": "ENSGALG00000033074", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033074", "database": "Bgee", "categories": [ "Gene Expression" ] 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"MANSTGKNHADQRRKGLAFLDELRQFHHSRGSPFKKIPVVGGKELDLHALYTRVTTLGGFGKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1830, "header": "tr|A0A1D5P2P6-1|A0A1D5P2P6_CHICK Isoform 1 of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2P6/entry", "sequence": { "sequence": "MANSTGKNHADQRRKGLAFLDELRQFHHSRGSPFKKIPVVGGKELDLHALYTRVTTLGGFGKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1830, "header": "tr|A0A1D5P2P6-1|A0A1D5P2P6_CHICK Isoform 1 of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30893334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033299.1", "url": "https://www.ensembl.org/id/ENSGALT00010033299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019657.1", "url": "https://www.ensembl.org/id/ENSGALP00010019657.1" } ] } }, { "isoform_ac": "A0A8V0YFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP1/entry", "sequence": { "sequence": "MFGAEGPAGPSRPSCVAWPQDLFFNTKMANSTGKNHADQRRKGLAFLDELRQFHHSRGSPFKKIPVVGGKELDLHALYTRVTTLGGFGKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1857, "header": "tr|A0A8V0YFP1-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30891752, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033312.1", "url": "https://www.ensembl.org/id/ENSGALT00010033312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019663.1", "url": "https://www.ensembl.org/id/ENSGALP00010019663.1" } ] } }, { "isoform_ac": "A0A8V0YNT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT4/entry", "sequence": { "sequence": "MVVLFCILFLVLTAYGGANIFCKSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 267, "header": "tr|A0A8V0YNT4-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30975185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033280.1", "url": "https://www.ensembl.org/id/ENSGALT00010033280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019646.1", "url": "https://www.ensembl.org/id/ENSGALP00010019646.1" } ] } }, { "isoform_ac": "A0A8V0YNT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT9/entry", "sequence": { "sequence": "MFNIDNRHGAWARNRASRPGGAGRCPPSPSRGKITKGAPKTVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1809, "header": "tr|A0A8V0YNT9-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30894098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033287.1", "url": "https://www.ensembl.org/id/ENSGALT00010033287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019651.1", "url": "https://www.ensembl.org/id/ENSGALP00010019651.1" } ] } }, { "isoform_ac": "A0A8V0YNV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV0/entry", "sequence": { "sequence": "MKKSIILGRRTRRYNQAIQSHNFPLVQSQLPITTSNTVCQITFVKAMGYLWTLTHQTIIINWCFHCYLDSQMKWILQLMYVLFFQMKASMSCSLKRTLKSSRYCLLMLGYLMTFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1708, "header": "tr|A0A8V0YNV0-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30951791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033306.1", "url": "https://www.ensembl.org/id/ENSGALT00010033306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019661.1", "url": "https://www.ensembl.org/id/ENSGALP00010019661.1" } ] } }, { "isoform_ac": "A0A8V0YTU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTU5/entry", "sequence": { "sequence": "MQAPVHRWQKCSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 255, "header": "tr|A0A8V0YTU5-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30981122, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033275.1", "url": "https://www.ensembl.org/id/ENSGALT00010033275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019644.1", "url": "https://www.ensembl.org/id/ENSGALP00010019644.1" } ] } }, { "isoform_ac": "A0A8V0YTV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV0/entry", "sequence": { "sequence": "MKAAVVVLSLYSGTFYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1750, "header": "tr|A0A8V0YTV0-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30950935, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033284.1", "url": "https://www.ensembl.org/id/ENSGALT00010033284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019649.1", "url": "https://www.ensembl.org/id/ENSGALP00010019649.1" } ] } }, { "isoform_ac": "A0A8V0YTV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV6/entry", "sequence": { "sequence": "MANSTGKNHADQRRKGLAFLDELRQFHHSRGSPFKKIPVVGGKELDLHALYTRVTTLGGFGKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEEDEEVQPGNPKPQLPIGAIPTSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSAVFGEEWKEKTDRDFVKGSFLPRQETNVEWTESNQASLLKPKKGDLGPSSRVKRRNRGCNLTLNLRCLNTFTQFWRDIVEDIEVRDLISDRSKSQDIPSEDWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEEGNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILANLCKAEDNGVLICEYVDQESYKEIICHLTLPDVLLVISALEVLYMLTEMGEVACTKISKVEKSIDTLVCLVSMDIQMFGPDALTAVKLIEHQCVSQQGVPDVRPPMMDHGSSQAHATGIAASRAAPHVAPPPGIVEIDSEKFACQWLNAHFEVNLDCSISRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDPINNGQAHIHVVGVKRRAIPLPIQMYYQQQPASSTPIVRVDSIPDMSASPSPAGLPHGPQSVGNHYQRTPINQSSTLTATQMSFPIQGVHTVAQTVSRIPQNTVHAQQQNAPMTVIQNKGPIPGEVMKATVIQSSVPQSGVPVTIAVGGAPQASNQNHSSTGPQPSVTVVGSQTLLHHQPVIQQQSPLHAVVPGQIPSGTPVTVIQQAVPQGHIFGRVQNIPACSSAVSQGQQLISTSSQPGQSSSQQSSTGNQQQDTVIIAPQQYVTTSASNIVSATTVQNFQVAPGQVVAIAGVQNPPTSRVGFQNIAPKPLPSQQVPPNVQQPMQSQQQPPQPPSQQSVVIVSQPAQQGQTYAPAIHQIVLANPASIPPGQTVQLTGQPSITPSSSPSPGPVTNNQVPTVMSSSSTPSQSQGPPPTVSQMLSVKRQQQQQQQQQHSPASSQQQVQPPMQMQVQSQQANTGVGQPNSGESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQMANNQTPGFGVQGQSSAQQLLVGQQLVQGAVQPQGAVQTVPISNLQILPGQLISNSPATIFQGTTGNQVTITVVPNTSFATATVSQGNATQIIAPAGIAVSGAQTGVGLQMQTLPATQAPSAGQSPCTAAPPFKGDKIICQKEEEAKEATGLHIHERKIEVMENPSCRRGAANTSNGDAKENEMQVGSLLNGRKYSDSSLPPSNSGKTQNEANQCSQVSNGPSLEMGENGAPGKQNFEQMDTQEIKSDLKKPLVNGICDFDKGDDHLSKNIPNHKTSNHVGNGEISSVEQQGNLDATQQDTAKGDQGERISNGPVLTLSSSPVVSGTQEAAKLLTQQLSGTNTDLPNGPLASSLNSDVPQQRPSVVVSPQSTASVIQGHQIIAVPHSGPRVSQSTLSSEVRSTNGTAECKIAKRPAEDNDRETVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQQPTTYIQSMVTQSTPATSIPTVQVQGQQLNLQPPSYTAASQHAEQMKKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSRDALLAGLKQDEPGQGGIQKPSNKPPVVGSTAATPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENHLSVLAISNMEASSTLAKCLYELNFTVQSKEHEKDSEMLQ", "length": 1886, "header": "tr|A0A8V0YTV6-1|A0A1D5P2P6_CHICK Computationally mapped isoform of AT-rich interaction domain 2 OS=Gallus gallus OX=9031 GN=ARID2 PE=4 SV=1 CANONICAL=A0A1D5P2P6-1" }, "locus": { "chromosome": "1", "start_pos": 30997671, "end_pos": 30893334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033293.1", "url": "https://www.ensembl.org/id/ENSGALT00010033293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019654.1", "url": "https://www.ensembl.org/id/ENSGALP00010019654.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1002, "start_aa": "Thr", "end_pos": 1002, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1002", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 992, "start_aa": "Thr", "end_pos": 992, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr992", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZJU0-1", "protein_name": "AT-rich interactive domain-containing protein 2", "gene_name": "Arid2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKPQLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWREKTDRDFVKFWKDIVDDNEVRDLISDRNKAHEDTPGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEESNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVTKCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVTSTLEVLYMLTEMGDIACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLVEHPSSSHQVLSEMRPQAIEQVQTQSHGAPGPACRAVVAQHAAPPPGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSSSGQAHIHVIGVRRRALPLPIQMYYQQQPVSTPVVRVDAVADVSPTPSPAGIPHGSQAVGNHFQRTPVTNQSSNLTATQMSFPVQGVHTVAQTVSRIPPNPSVHTHQQQNSPVTVIQNKAPIPCEVVKATVIQNSVPQTAVPVSIAVGGPAQSSLAQNHSAGPQPVTVVNSQTLLHHPSVMPQPSPLHTVVPGQIPSGTPVTVIQQTVPQSHIFGRVQNIPACTSTVSQGQQLITTSPQPMHTSSQQTAAGSQPQDTVIIAPPQYVTTSASSIVSATSVQNFQVATGQVVTIAGVPSPQPSRVGFQNIAPKPLPSQHVSSTVVQQPVQQPQQPAQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPTGQTVQLTGQPNITPSSSPSPVPATSNQVPAAMSSSSTLQSQGPPPTVSQMLSVKRQQQQQHSPAAPAQQVQVQVQPPQVQVQVQPQQAGAGVGQPASSESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVANSQAAGFGAQGQTPAQQLLVGQPNVQLVQSAMPPTGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFATATVSQGNAAQLIAPAGISMSGAQAGAGLQVQTLPAGQSACTSAAPPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGTTNTSNGDTSESETQVGSLLNGRKYSDSSLPPSHSGKLQSEPNPCSPLSNGPSLELGENGASGKQNSEPVDMQDVKSDLKKTLVNGICDFDKGDGSHLSKNIPNHKTCNHVGNGEVSPVEPQGTLGATQQETAKGDQLERVPNGPALTLGGSPATSSVQEASSVATQPFSGTDLPNGPLASGLTSDVPHQRPSVVVSPRPTAPVIQGHPVIAAPHSGSRGPASALSSDARSTNGTAECKTVKRPAEDGDREAAPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIGSAAQQKPPPPPAYAQSALPQNTPMPPSPAVQVQGQPSSSQPSPVSASSQHADPVRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQAANQKSSTKQPTVGSTGSAPRAQKAIASHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEQDSEML", "length": 1826 }, "evidence": [ { "id": "A0A1D5P2P6", "url": "https://omabrowser.org/oma/group/A0A1D5P2P6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q7E2-1", "protein_name": "AT-rich interactive domain-containing protein 2", "gene_name": "Arid2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKPQLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSSVFGEEWREKTDRDFVKFWKDIVDDNEVRDLISDRNKAHEDTPGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEESNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFRTTHLMFHTVTKCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVTSTLEVLYMLTEMGDVACTKIAKVEKSIDVLVCLVSMDAQMFGPDALAAVKLIEHPSSSHQVLSEIRPQAIEQVQTQTHIASGPASRAVVAQHAAPPPGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSTSSGQAHIHVIGVKRRALPLPIQMYYQQQPISTPVVRVDAVADLSPTPSPAGIPHGPQAAGNHFQRTPVTNQSSNLTATQMSFPVQGIHTVAQTVSRIPPNPSVHTHQQQNSPVTVIQNKAPIPCEVVKATVIQNSVPQTAVPVSISVGGAPAQNSVGQNHSAGPQPVTVVNSQTLLHHPSVMPQPSPLHTVVPGQVPSGTPVTVIQQTVPQSRMFGRVQSIPACTSTVSQGQQLITTSPQPMHTSSQQTAAGSQPQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQVVTIAGVPSPQPSRVGFQNIAPKPLPSQQVSPSVVQQPIQQPQQPAQQSVVIVSQPAQQGQAYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSSSPSPVPPTNNQVPTAMSSSSTLQSQGPPPTVSQMLSVKRQQQQQHSPAAPAQQVQVQVQQPQQVQVQVQPQQPSAGVGQPAPNESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVANNQAAGFGVQGQTPAQQLLVGQQNVQLVQSAMPPAGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFATATVSQGNAAQLIAPAGLSMSGAQASAGLQVQTLPAGQSACTTAPLPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGTTNTSNGDTSESELQVGSLLNGRKYSDSSLPPSNSGKLQSETSQCSLISNGPSLELGENGAPGKQNSEPVDMQDVKGDLKKALVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPVEPQGTSGATQQDTAKGDQLERVSNGPVLTLGGSPSTSSMQEAPSVATPPLSGTDLPNGPLASSLNSDVPQQRPSVVVSPHSTAPVIQGHQVIAVPHSGPRVTPSALSSDARSTNGTAECKTVKRPAEDNDRDTVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAAQQKQQHPPTYMQSVAPQNTPMPPSPAVQVQGQPSSSQPSPVSASSQHADPVRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQVANQKSSTKQPTVGGTGSAPRAQKAIASHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEML", "length": 1828 }, "evidence": [ { "id": "A0A1D5P2P6", "url": "https://omabrowser.org/oma/group/A0A1D5P2P6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6NXG0-1", "protein_name": "AT-rich interactive domain-containing protein 2 isoform X1", "gene_name": "arid2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"length": 1572 }, "evidence": [ { "id": "A0A1D5P2P6", "url": "https://omabrowser.org/oma/group/A0A1D5P2P6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68CP9-1", "protein_name": "AT-rich interactive domain-containing protein 2", "gene_name": "ARID2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"uniprot_canonical_ac": "A0A1D5P292-1", "uniprot_ac": "A0A1D5P292", "uniprot_id": "A0A1D5P292_CHICK", "mass": { "chemical_mass": 17420.0, "monoisotopic_mass": 17420.0 }, "refseq": { "ac": "XP_001232925", "name": "transmembrane protein 50A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232925" }, "gene_names": [ { "name": "TMEM50A", "type": "recommended", "evidence": [ { "id": "A0A1D5P292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ] }, { "name": "TMEM50A", "type": "synonym", "evidence": [ { "id": "XP_001232925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232925" } ] } ], "protein_names": [ { "name": "Transmembrane protein 50A", "type": "synonym", "evidence": [ { "id": "A0A1D5P292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 50A", "type": "synonym", "evidence": [ { "id": "XP_001232925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232925" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001232925.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232925" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM50A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292", "locus": { "chromosome": "23", "start_pos": 2752048, "end_pos": 2761763, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015769", "url": "https://www.ensembl.org/id/ENSGALG00010015769" } ] } } ], "crossref": [ { "id": "A0A1D5P292", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P292", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043733", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043733", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769637", "url": "https://www.ncbi.nlm.nih.gov/gene/769637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769637", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYVVPQK", "url": "https://omabrowser.org/oma/group/GYVVPQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P292", "url": "https://www.orthodb.org/?gene=A0A1D5P292", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZY0", "url": "https://www.orthodb.org/?gene=A0A8V0YZY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P292-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGFLESLRCSECVDWGEKRNTIASVAAGVLFFTGWWIIIDAAVKYPTMEDFNHSYHACGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMMAFGSLIASMWILFGGYVVKEKAVVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ", "length": 157, "header": "tr|A0A1D5P292-1|A0A1D5P292_CHICK Isoform 1 of Transmembrane protein 50A OS=Gallus gallus OX=9031 GN=TMEM50A PE=3 SV=1 CANONICAL=A0A1D5P292-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P292-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292/entry", "sequence": { "sequence": "MSGFLESLRCSECVDWGEKRNTIASVAAGVLFFTGWWIIIDAAVKYPTMEDFNHSYHACGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMMAFGSLIASMWILFGGYVVKEKAVVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ", "length": 157, "header": "tr|A0A1D5P292-1|A0A1D5P292_CHICK Isoform 1 of Transmembrane protein 50A OS=Gallus gallus OX=9031 GN=TMEM50A PE=3 SV=1 CANONICAL=A0A1D5P292-1" }, "locus": { "chromosome": "23", "start_pos": 2761529, "end_pos": 2757359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037967.1", "url": "https://www.ensembl.org/id/ENSGALT00010037967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021905.1", "url": "https://www.ensembl.org/id/ENSGALP00010021905.1" } ] } }, { "isoform_ac": "A0A8V0YZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY0/entry", "sequence": { "sequence": "MSGFLESLRCSECVDWGEKRNTIASVAAGVLFFTGWWIIIDAAVKYPTMEDFNHSYHACGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMMAFGSLIASMWILFGGYVVKESSGVPRNCCFFPECVHLFWNQQLQNYCSCHKTNRMPREEHVSLDGPKPPATKGAVPGSHNLLT", "length": 186, "header": "tr|A0A8V0YZY0-1|A0A1D5P292_CHICK Computationally mapped isoform of Transmembrane protein 50A OS=Gallus gallus OX=9031 GN=TMEM50A PE=3 SV=1 CANONICAL=A0A1D5P292-1" }, "locus": { "chromosome": "23", "start_pos": 2761529, "end_pos": 2754022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037972.1", "url": "https://www.ensembl.org/id/ENSGALT00010037972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021906.1", "url": "https://www.ensembl.org/id/ENSGALP00010021906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769637", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9CXL1-1", "protein_name": "Transmembrane protein 50A", "gene_name": "Tmem50a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGFLEGSRCSECMDWGEKRNTIASIAAGVLFFTGWWIIIDAAVMYPRMDQFNHSYHTCGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDVVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ", "length": 157 }, "evidence": [ { "id": "A0A1D5P292", "url": "https://omabrowser.org/oma/group/A0A1D5P292/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZE2-1", "protein_name": "Transmembrane protein 50A", "gene_name": "Dmel\\CG15012", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGVLDNIALHFTGDASRNRNTSIIAGLLFFAGWWVLIDAMSIDGKHQITTGHVFIGIFGTISFCMVNAVKGEHISDENSSESGARIAKIWLLVGFLMGFASIIAAIWVMIDDFINNEKKDGWFGVALLMQNVFILFASLVYKFGRNEEEWNE", "length": 152 }, "evidence": [ { "id": "A0A1D5P292", "url": "https://omabrowser.org/oma/group/A0A1D5P292/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "pmid": "" }, { "name": "glial cell projection", "id": "GO:0097386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097386", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P292", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P292" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NV75-1", "uniprot_ac": "A0A1D5NV75", "uniprot_id": "A0A1D5NV75_CHICK", "mass": { "chemical_mass": 33245.0, "monoisotopic_mass": 33245.0 }, "refseq": { "ac": "XP_015127972", "name": "alpha-soluble NSF attachment protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972" }, "gene_names": [ { "name": "NAPA", "type": "recommended", "evidence": [ { "id": "A0A1D5NV75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ] }, { "name": "NAPA", "type": "synonym", "evidence": [ { "id": "XP_015127972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972" } ] } ], "protein_names": [ { "name": "NSF attachment protein alpha", "type": "synonym", "evidence": [ { "id": "A0A1D5NV75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75/entry#names_and_taxonomy" } ] }, { "name": "alpha-soluble NSF attachment protein", "type": "synonym", "evidence": [ { "id": "XP_015127972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052569.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015127972.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015127972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972" } ] }, { "annotation": "Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUZ0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUZ0#function" }, { "database": "UniProtKB", "id": "RU367013", "url": "https://www.uniprot.org/uniprotkb/RU367013#function" }, { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAPA", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75", "locus": { "chromosome": "38", "start_pos": 190048, "end_pos": 196395, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010781", "url": "https://www.ensembl.org/id/ENSGALG00010010781" } ] } } ], "crossref": [ { "id": "A0A1D5NV75", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NV75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034747", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15832", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15832", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858304", "url": "https://www.ncbi.nlm.nih.gov/gene/100858304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858304", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858304", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSVKEYL", "url": "https://omabrowser.org/oma/group/WSVKEYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUZ0", "url": "https://www.orthodb.org/?gene=A0A1D5NUZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NV75", "url": "https://www.orthodb.org/?gene=A0A1D5NV75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13768:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13768:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14938", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14938", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015127972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127972", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUZ0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NV75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQAGKEKEALQLLAEADRKVRGSQSFFAGLFGGSSRIEEACDIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATNFVDAGNAFKKADPQEAINCLIRAIEIYTDMGRFTIAAKHHISIAEIYESELVDIEKAIAHYEQAADYYKGEESNSSANKCLLKVATYAAQLEQYQKAVEIYEQVGTSAMDSPLLKYSAKEYFFKAALCHFCIDMLNAKLAVQKYEEMFPAFTDSRECKLVKKLLDAHEEQNVDAYTDAVKEYDSISRLDQWLTTMLLRIKKTIQGEEEDLR", "length": 295, "header": "tr|A0A1D5NV75-1|A0A1D5NV75_CHICK Isoform 1 of NSF attachment protein alpha OS=Gallus gallus OX=9031 GN=NAPA PE=3 SV=2 CANONICAL=A0A1D5NV75-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUZ0/entry", "sequence": { "sequence": "MLSAVGSPTSHGSIPLGLAFPVLWGSPTRCHSSSLGWDSHRIDLCSLLPSRGSSRIEEACDIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATNFVDAGNAFKKADPQEAINCLIRAIEIYTDMGRFTIAAKHHISIAEIYESELVDIEKAIAHYEQAADYYKGEESNSSANKCLLKVATYAAQLEQYQKAVEIYEQVGTSAMDSPLLKYSAKEYFFKAALCHFCIDMLNAKLAVQKYEEMFPAFTDSRECKLVKKLLDAHEEQNVDAYTDAVKEYDSISRLDQWLTTMLLRIKKTIQGEEEDLR", "length": 313, "header": "tr|A0A1D5NUZ0-1|A0A1D5NV75_CHICK Computationally mapped isoform of NSF attachment protein alpha OS=Gallus gallus OX=9031 GN=NAPA PE=3 SV=2 CANONICAL=A0A1D5NV75-1" }, "locus": { "chromosome": "38", "start_pos": 194761, "end_pos": 190369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025780.1", "url": "https://www.ensembl.org/id/ENSGALT00010025780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014525.1", "url": "https://www.ensembl.org/id/ENSGALP00010014525.1" } ] } }, { "isoform_ac": "A0A1D5NV75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75/entry", "sequence": { "sequence": "MDQAGKEKEALQLLAEADRKVRGSQSFFAGLFGGSSRIEEACDIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATNFVDAGNAFKKADPQEAINCLIRAIEIYTDMGRFTIAAKHHISIAEIYESELVDIEKAIAHYEQAADYYKGEESNSSANKCLLKVATYAAQLEQYQKAVEIYEQVGTSAMDSPLLKYSAKEYFFKAALCHFCIDMLNAKLAVQKYEEMFPAFTDSRECKLVKKLLDAHEEQNVDAYTDAVKEYDSISRLDQWLTTMLLRIKKTIQGEEEDLR", "length": 295, "header": "tr|A0A1D5NV75-1|A0A1D5NV75_CHICK Isoform 1 of NSF attachment protein alpha OS=Gallus gallus OX=9031 GN=NAPA PE=3 SV=2 CANONICAL=A0A1D5NV75-1" }, "locus": { "chromosome": "38", "start_pos": 196196, "end_pos": 190369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025784.1", "url": "https://www.ensembl.org/id/ENSGALT00010025784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014528.1", "url": "https://www.ensembl.org/id/ENSGALP00010014528.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858304", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "P32602-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "SEC17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDPVELLKRAEKKGVPSSGFMKLFSGSDSYKFEEAADLCVQAATIYRLRKELNLAGDSFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLENAIQIFTHRGQFRRGANFKFELGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKCFIKCADLKALDGQYIEASDIYSKLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGDSEQLSEHCKEFDNFMRLDKWKITILNKIKESIQQQEDDLL", "length": 292 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54920-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "NAPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "length": 295 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54921-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "Napa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSGKQAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "length": 295 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q23983-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "alphaSnap", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDNEQKALQLMAEAEKKLTQQKGFLGSLFGGSNKVEDAIECYQRAGNMFKMSKNWTKAGECFCEAATLHARAGSRHDAGTCYVDASNCYKKVDVESAVNCLMKSIDIYTDMGRFTMAAKHHQSIAEMYESDPNNLAKSIQHYEQAADYFKGEESVSSANKCMLKVAQYAAQLEDYEKAISIYEQVAASSLESSLLKYSAKEYFFRAALCHLSVDLLNAQHAIEKYAQQYPAFQDSREFKLIKVLCENLEEQNIEGFTEAVKDYDSISRLDQWYTTILLRIKKAADEDPDLR", "length": 292 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54NP6-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "snpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGDDAKAKEFLDAADKRLRGGNFFKMFGGGSSRYDDAASDYTKAANLFKMSKKWDQAGAAFQKAAECFLKGSSKHDAASSYVLAAGCYKKGNVIDAITCLKAAIEYYTDEGRFAISAKHQKEIAELYEAEGDFDQAIASYQIASDYFDGENSTVSSHQCLLKIALFSAQLERYEKSIEIYEQVAAASLDNNLTQWGCKEYFLRACLCYLAADDVVGAERALQRYKDMQASFNSTRECRLLDGIIQACRNNNVEDFTNEVAEFNSISPLDSWKTSILLRIKNTINRETESVV", "length": 291 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB05-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "Napa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNSGKQAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTEAVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "length": 295 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SPE6-1", "protein_name": "Alpha-soluble NSF attachment protein 2", "gene_name": "ASNAP2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDHLVRAEEFEKKAEKKLNGWGIFGSKYEDAADLLEKAANSYKLAKSWDQAGKAYLKLADCHLKSDSKHDAANAYAEAAKCYKKVDTNEAASCLERAVNIFCEIGRLNMAARYYKEIAEYYESDQKFEQAIAYFEKAAEFFQNEEVTTSANQCNLKVAQYAAQLEQYEKAIKIYEDIARHSLNNNLLKYGVKGHLLTAGMCHLCKADVVSITNALEKYQDLDPTFTGTRECKFLADLASAIDEEDIAKFTDVVKEFDSMTPLDSWKTTMLLRVKEKLKAKELEEDDLT", "length": 289 }, "evidence": [ { "id": "A0A1D5NV75", "url": "https://omabrowser.org/oma/group/A0A1D5NV75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "SNARE complex disassembly", "id": "GO:0035494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035494", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle priming", "id": "GO:0010807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010807", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "synaptobrevin 2-SNAP-25-syntaxin-1a complex", "id": "GO:0070044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070044", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" }, { "name": "soluble NSF attachment protein activity", "id": "GO:0005483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005483", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLH6-1", "uniprot_ac": "A0A8V0YLH6", "uniprot_id": "A0A8V0YLH6_CHICK", "mass": { "chemical_mass": 69657.0, "monoisotopic_mass": 69657.0 }, "refseq": { "ac": "XP_025010786", "name": "kelch-like protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010786" }, "gene_names": [ { "name": "KLHL3", "type": "recommended", "evidence": [ { "id": "A0A8V0YLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ] }, { "name": "KLHL3", "type": "synonym", "evidence": [ { "id": "XP_025010786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010786" } ] } ], "protein_names": [ { "name": "Kelch-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025010786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010786" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010786.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010786" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6", "locus": { "chromosome": "13", "start_pos": 14132479, "end_pos": 14057245, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015660", "url": "https://www.ensembl.org/id/ENSGALG00010015660" } ] } } ], "crossref": [ { "id": "A0A8V0YLH6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039124", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039124", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416303", "url": "https://www.ncbi.nlm.nih.gov/gene/416303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416303", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P186", "url": "https://www.orthodb.org/?gene=A0A1D5P186", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025010786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P186", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P186", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P186-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P186-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P790", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P790", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P790-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P790-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSSHLDMLWRLSRKKGRISSRRTKDNPLSARKPCCMGLLFLFSIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 625, "header": "tr|A0A8V0YLH6-1|A0A8V0YLH6_CHICK Isoform 1 of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P186-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P186/entry", "sequence": { "sequence": "MEEESIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 586, "header": "tr|A0A1D5P186-1|A0A8V0YLH6_CHICK Computationally mapped isoform of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14093467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037743.1", "url": "https://www.ensembl.org/id/ENSGALT00010037743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021801.1", "url": "https://www.ensembl.org/id/ENSGALP00010021801.1" } ] } }, { "isoform_ac": "A0A1D5P790-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P790/entry", "sequence": { "sequence": "MVSDPSRKSESSIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 593, "header": "tr|A0A1D5P790-1|A0A8V0YLH6_CHICK Computationally mapped isoform of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14095404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037728.1", "url": "https://www.ensembl.org/id/ENSGALT00010037728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021795.1", "url": "https://www.ensembl.org/id/ENSGALP00010021795.1" } ] } }, { "isoform_ac": "A0A8V0YLH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6/entry", "sequence": { "sequence": "MYSSHLDMLWRLSRKKGRISSRRTKDNPLSARKPCCMGLLFLFSIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 625, "header": "tr|A0A8V0YLH6-1|A0A8V0YLH6_CHICK Isoform 1 of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14089328, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037754.1", "url": "https://www.ensembl.org/id/ENSGALT00010037754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021808.1", "url": "https://www.ensembl.org/id/ENSGALP00010021808.1" } ] } }, { "isoform_ac": "A0A8V0YSU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU2/entry", "sequence": { "sequence": "MGKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 544, "header": "tr|A0A8V0YSU2-1|A0A8V0YLH6_CHICK Computationally mapped isoform of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14102329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037706.1", "url": "https://www.ensembl.org/id/ENSGALT00010037706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021785.1", "url": "https://www.ensembl.org/id/ENSGALP00010021785.1" } ] } }, { "isoform_ac": "A0A8V0YSU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSU7/entry", "sequence": { "sequence": "MEMERDCCKANAWKICSIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 598, "header": "tr|A0A8V0YSU7-1|A0A8V0YLH6_CHICK Computationally mapped isoform of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14099388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037719.1", "url": "https://www.ensembl.org/id/ENSGALT00010037719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021790.1", "url": "https://www.ensembl.org/id/ENSGALP00010021790.1" } ] } }, { "isoform_ac": "A0A8V0YT87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT87/entry", "sequence": { "sequence": "MPLLSCSEGPCLFGERMRRWNPEKHTMNVLIKQSSRSSEAGEDEKDQRTVTVNPSHMRKAFRVMNELRSKRLLCDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLRKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRKNCCDFLQSQLHPTNCLGIRAFADVHACTELLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKESRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRQLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEERWDQVAELPSRRCRAGVVFMAGNVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWTYVADMSTRRSGAGVGVLSGLLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPITDKWTLLPTSMSTGRSYAGVAVIHKPL", "length": 611, "header": "tr|A0A8V0YT87-1|A0A8V0YLH6_CHICK Computationally mapped isoform of Kelch-like protein 3 OS=Gallus gallus OX=9031 GN=KLHL3 PE=3 SV=1 CANONICAL=A0A8V0YLH6-1" }, "locus": { "chromosome": "13", "start_pos": 14130709, "end_pos": 14063917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037763.1", "url": "https://www.ensembl.org/id/ENSGALT00010037763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021812.1", "url": "https://www.ensembl.org/id/ENSGALP00010021812.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416303", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "monoatomic ion homeostasis", "id": "GO:0050801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050801", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "renal sodium ion absorption", "id": "GO:0070294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" }, { "name": "distal tubule morphogenesis", "id": "GO:0072156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH6" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", 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"categories": [ "Protein Classification" ] }, { "id": "IPR034445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PKJ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKJ9-1", "url": 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"MTAEDSAARMSNDSTNVSTTKVPEGVAGAPNEAALLALMERTGYSMIQENGQRKYGGPPPGWDGLHPPRGCEVFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKVFGQFNPGCVERVKKIRDYAFVHFTTREDAIHAMNNLNGVELEGSCLEVTLAKPVDKEQYTRYQKAAKGGAAATPEVTQQPNYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLELPAVNPVAIKPVAIPAIGAQYSMFPAAPPAKMMEDGKIHAVEHIINPIAVQQDPASAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTMAPNVQRIPAAGIYGTSYVPFAAPAAATATIATLQKNAAAAAAAAAAYGGYAGYIPPAFPAATIQVPIHDVYQTY", "length": 595, "header": "tr|A0A8V0YMK0-1|A0A8V0YMK0_CHICK Isoform 1 of RNA-binding protein 47 OS=Gallus gallus OX=9031 GN=RBM47 PE=1 SV=1 CANONICAL=A0A8V0YMK0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKJ9/entry", "sequence": { "sequence": "MTAEDSAARMSNDSTNVSTTKVPEGVAGAPNEAALLALMERTGYSMIQENGQRKYGGPPPGWDGLHPPRGCEVFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKVFGQFNPGCVERVKKIRDYAFVHFTTREDAIHAMNNLNGVELEGSCLEVTLAKPVDKEQYTRYQKAAKGGAAATPEVTQQPNYVYSCDPYTLAYYGYPYNALIGPNRDYFVKG", "length": 377, "header": "tr|A0A1D5PKJ9-1|A0A8V0YMK0_CHICK Computationally mapped isoform of RNA-binding protein 47 OS=Gallus gallus OX=9031 GN=RBM47 PE=1 SV=2 CANONICAL=A0A8V0YMK0-1" }, "locus": { "chromosome": "4", "start_pos": 68455834, "end_pos": 68454704, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038397.1", "url": "https://www.ensembl.org/id/ENSGALT00010038397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022205.1", "url": "https://www.ensembl.org/id/ENSGALP00010022205.1" } ] } }, { "isoform_ac": "A0A8V0YMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0/entry", "sequence": { "sequence": "MTAEDSAARMSNDSTNVSTTKVPEGVAGAPNEAALLALMERTGYSMIQENGQRKYGGPPPGWDGLHPPRGCEVFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKVFGQFNPGCVERVKKIRDYAFVHFTTREDAIHAMNNLNGVELEGSCLEVTLAKPVDKEQYTRYQKAAKGGAAATPEVTQQPNYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLELPAVNPVAIKPVAIPAIGAQYSMFPAAPPAKMMEDGKIHAVEHIINPIAVQQDPASAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTMAPNVQRIPAAGIYGTSYVPFAAPAAATATIATLQKNAAAAAAAAAAYGGYAGYIPPAFPAATIQVPIHDVYQTY", "length": 595, "header": "tr|A0A8V0YMK0-1|A0A8V0YMK0_CHICK Isoform 1 of RNA-binding protein 47 OS=Gallus gallus OX=9031 GN=RBM47 PE=1 SV=1 CANONICAL=A0A8V0YMK0-1" }, "locus": { "chromosome": "4", "start_pos": 68454924, "end_pos": 68448651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038402.1", "url": "https://www.ensembl.org/id/ENSGALT00010038402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022209.1", "url": "https://www.ensembl.org/id/ENSGALP00010022209.1" } ] } }, { "isoform_ac": "A0A8V0YTY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY7/entry", "sequence": { "sequence": "MTAEDSAARMSNDSTNVSTTKVPEGVAGAPNEAALLALMERTGYSMIQENGQRKYGGPPPGWDGLHPPRGCEVFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKVFGQFNPGCVERVKKIRDYAFVHFTTREDAIHAMNNLNGVELEGSCLEVTLAKPVDKEQYTRYQKAAKGGAAATPEVTQQPNYVYSCDPYTLAYYGYPYNALIGPNRDYFVKGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLELPAVNPVAIKPVAIPAIGAQYSMFPAAPPAKMMEDGKIHAVEHIINPIAVQQDPASAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTMAPNVQRIPAAGIYGTSYVPFAAPAAATATIATLQKNAAAAAAAAAAYGGYAGYIPPAFPAATIQVPIHDVYQTY", "length": 594, "header": "tr|A0A8V0YTY7-1|A0A8V0YMK0_CHICK Computationally mapped isoform of RNA-binding protein 47 OS=Gallus gallus OX=9031 GN=RBM47 PE=1 SV=1 CANONICAL=A0A8V0YMK0-1" }, "locus": { "chromosome": "4", "start_pos": 68454924, "end_pos": 68448651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038393.1", "url": "https://www.ensembl.org/id/ENSGALT00010038393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022201.1", "url": "https://www.ensembl.org/id/ENSGALP00010022201.1" } ] } }, { "isoform_ac": "A0A8V0YUA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA7/entry", "sequence": { "sequence": "MTAEDSAARMSNDSTNVSTTKVPEGVAGAPNEAALLALMERTGYSMIQENGQRKYGGPPPGWDGLHPPRGCEVFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKVFGQFNPGCVERVKKIRDYAFVHFTTREDAIHAMNNLNGVELEGSCLEVTLAKPVDKEQYTRYQKAAKGGAAATPEVTQQPNYVYSCDPYTLAYYGYPYNALIGPNRDYFVK", "length": 376, "header": "tr|A0A8V0YUA7-1|A0A8V0YMK0_CHICK Computationally mapped isoform of RNA-binding protein 47 OS=Gallus gallus OX=9031 GN=RBM47 PE=1 SV=1 CANONICAL=A0A8V0YMK0-1" }, "locus": { "chromosome": "4", "start_pos": 68449778, "end_pos": 68448651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038390.1", "url": "https://www.ensembl.org/id/ENSGALT00010038390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022198.1", "url": "https://www.ensembl.org/id/ENSGALP00010022198.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" }, { "name": "apolipoprotein B mRNA editing enzyme complex", "id": "GO:0030895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK0", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P2A9-1", "uniprot_ac": "A0A1D5P2A9", "uniprot_id": "A0A1D5P2A9_CHICK", "mass": { "chemical_mass": 67918.0, "monoisotopic_mass": 67918.0 }, "refseq": { "ac": "NP_001026500", "name": "kelch-like protein 20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500" }, "gene_names": [ { "name": "KLHL20", "type": "recommended", "evidence": [ { "id": "A0A1D5P2A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ] }, { "name": "KLHL20", "type": "synonym", "evidence": [ { "id": "NP_001026500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500" } ] } ], "protein_names": [ { "name": "Kelch-like protein 20", "type": "recommended", "evidence": [ { "id": "A0A1D5P2A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 20", "type": "synonym", "evidence": [ { "id": "NP_001026500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500" } ] }, { "name": "kelch-like protein 20", "type": "synonym", "evidence": [ { "id": "NP_001026500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720145.1, ERR2368565.237289.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Oct 25, 2021 this sequence version replaced NP_001026500.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9", "locus": { "chromosome": "8", "start_pos": 5553520, "end_pos": 5529335, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010743", "url": "https://www.ensembl.org/id/ENSGALG00010010743" } ] } } ], "crossref": [ { "id": "A0A1D5P2A9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P2A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036931", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036931", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425091", "url": "https://www.ncbi.nlm.nih.gov/gene/425091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425091", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAVFNNL", "url": "https://omabrowser.org/oma/group/CAVFNNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2A9", "url": "https://www.orthodb.org/?gene=A0A1D5P2A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PY38", "url": "https://www.orthodb.org/?gene=A0A1D5PY38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1K9", "url": "https://www.orthodb.org/?gene=A0A8V0Y1K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7S6", "url": "https://www.orthodb.org/?gene=A0A8V0Y7S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY38-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGKPMRRCTSTRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609, "header": "tr|A0A1D5P2A9-1|A0A1D5P2A9_CHICK Isoform 1 of Kelch-like protein 20 OS=Gallus gallus OX=9031 GN=KLHL20 PE=4 SV=1 CANONICAL=A0A1D5P2A9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9/entry", "sequence": { "sequence": "MDGKPMRRCTSTRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609, "header": "tr|A0A1D5P2A9-1|A0A1D5P2A9_CHICK Isoform 1 of Kelch-like protein 20 OS=Gallus gallus OX=9031 GN=KLHL20 PE=4 SV=1 CANONICAL=A0A1D5P2A9-1" }, "locus": { "chromosome": "8", "start_pos": 5548894, "end_pos": 5530605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025657.1", "url": "https://www.ensembl.org/id/ENSGALT00010025657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014460.1", "url": "https://www.ensembl.org/id/ENSGALP00010014460.1" } ] } }, { "isoform_ac": "A0A1D5PY38-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY38/entry", "sequence": { "sequence": "MDGKPMRRCTSTRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIWVNGI", "length": 613, "header": "tr|A0A1D5PY38-1|A0A1D5P2A9_CHICK Computationally mapped isoform of Kelch-like protein 20 OS=Gallus gallus OX=9031 GN=KLHL20 PE=4 SV=2 CANONICAL=A0A1D5P2A9-1" }, "locus": { "chromosome": "8", "start_pos": 5553294, "end_pos": 5530605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025664.1", "url": "https://www.ensembl.org/id/ENSGALT00010025664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014464.1", "url": "https://www.ensembl.org/id/ENSGALP00010014464.1" } ] } }, { "isoform_ac": "A0A8V0Y1K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K9/entry", "sequence": { "sequence": "MQLKFNSEECLLWLYQKCSVIDRKRIVRVNQDDDRCTSTRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 636, "header": "tr|A0A8V0Y1K9-1|A0A1D5P2A9_CHICK Computationally mapped isoform of Kelch-like protein 20 OS=Gallus gallus OX=9031 GN=KLHL20 PE=4 SV=1 CANONICAL=A0A1D5P2A9-1" }, "locus": { "chromosome": "8", "start_pos": 5548894, "end_pos": 5531118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025649.1", "url": "https://www.ensembl.org/id/ENSGALT00010025649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014457.1", "url": "https://www.ensembl.org/id/ENSGALP00010014457.1" } ] } }, { "isoform_ac": "A0A8V0Y7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S6/entry", "sequence": { "sequence": "MDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 591, "header": "tr|A0A8V0Y7S6-1|A0A1D5P2A9_CHICK Computationally mapped isoform of Kelch-like protein 20 OS=Gallus gallus OX=9031 GN=KLHL20 PE=4 SV=1 CANONICAL=A0A1D5P2A9-1" }, "locus": { "chromosome": "8", "start_pos": 5548894, "end_pos": 5535895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025654.1", "url": "https://www.ensembl.org/id/ENSGALT00010025654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014459.1", "url": "https://www.ensembl.org/id/ENSGALP00010014459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425091", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8N4-1", "protein_name": "Kelch-like protein 20", "gene_name": "Klhl20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QC58-1", "protein_name": "Kelch-like protein 20", "gene_name": "klhl20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDITSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 591 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08DK3-1", "protein_name": "Kelch-like protein 20", "gene_name": "KLHL20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VCK5-1", "protein_name": "Kelch-like protein 20", "gene_name": "Klhl20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 604 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VUU5-1", "protein_name": "Kelch-like protein diablo", "gene_name": "dbo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDLPGSGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS", "length": 623 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2M5-1", "protein_name": "Kelch-like protein 20", "gene_name": "KLHL20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609 }, "evidence": [ { "id": "A0A1D5P2A9", "url": "https://omabrowser.org/oma/group/A0A1D5P2A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "protein K33-linked ubiquitination", "id": "GO:1990390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990390", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" }, { "name": "type II interferon binding", "id": "GO:0019964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019964", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2A9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P2A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2A9" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 135, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPZ1-1", "uniprot_ac": "A0A8V0YPZ1", "uniprot_id": "A0A8V0YPZ1_CHICK", "mass": { "chemical_mass": 20049.0, "monoisotopic_mass": 20049.0 }, "refseq": {}, "gene_names": [ { "name": "TRAPPC3", "type": "recommended", "evidence": [ { "id": "A0A8V0YPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit", "type": "recommended", "evidence": [ { "id": "A0A8V0YPZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in vesicular transport from endoplasmic reticulum to Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU20#function" }, { "database": "UniProtKB", "id": "ARBA00002910", "url": "https://www.uniprot.org/uniprotkb/ARBA00002910#function" }, { "database": "UniProtKB", "id": "PIRNR018293", "url": "https://www.uniprot.org/uniprotkb/PIRNR018293#function" }, { "database": "UniProtKB", "id": "A0A8V0YIK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK0#function" }, { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1#function" }, { "database": "UniProtKB", "id": "A0A8V0YQ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1", "locus": { "chromosome": "23", "start_pos": 4466316, "end_pos": 4451959, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014859", "url": "https://www.ensembl.org/id/ENSGALG00010014859" } ] } } ], "crossref": [ { "id": "A0A8V0YPZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002284", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002284", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14942", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14942", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419625", "url": "https://www.ncbi.nlm.nih.gov/gene/419625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVQMQVQ", "url": "https://omabrowser.org/oma/group/MVQMQVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TU20", "url": "https://www.orthodb.org/?gene=A0A3Q2TU20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIK0", "url": "https://www.orthodb.org/?gene=A0A8V0YIK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YPZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ00", "url": "https://www.orthodb.org/?gene=A0A8V0YQ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TU20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TU20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQAGRGTESKKMNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 178, "header": "tr|A0A8V0YPZ1-1|A0A8V0YPZ1_CHICK Isoform 1 of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=3 SV=1 CANONICAL=A0A8V0YPZ1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TU20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU20/entry", "sequence": { "sequence": "MSRQAGRGTESKKMYWYLPFISPSASMHLMNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 196, "header": "tr|A0A3Q2TU20-1|A0A8V0YPZ1_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=3 SV=1 CANONICAL=A0A8V0YPZ1-1" }, "locus": { "chromosome": "23", "start_pos": 4464793, "end_pos": 4461169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035754.1", "url": "https://www.ensembl.org/id/ENSGALT00010035754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020730.1", "url": "https://www.ensembl.org/id/ENSGALP00010020730.1" } ] } }, { "isoform_ac": "A0A8V0YIK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK0/entry", "sequence": { "sequence": "MSRSRPAPSRPLESLLNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 182, "header": "tr|A0A8V0YIK0-1|A0A8V0YPZ1_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=3 SV=1 CANONICAL=A0A8V0YPZ1-1" }, "locus": { "chromosome": "23", "start_pos": 4464793, "end_pos": 4461830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035760.1", "url": "https://www.ensembl.org/id/ENSGALT00010035760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020735.1", "url": "https://www.ensembl.org/id/ENSGALP00010020735.1" } ] } }, { "isoform_ac": "A0A8V0YPZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1/entry", "sequence": { "sequence": "MSRQAGRGTESKKMNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 178, "header": "tr|A0A8V0YPZ1-1|A0A8V0YPZ1_CHICK Isoform 1 of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=3 SV=1 CANONICAL=A0A8V0YPZ1-1" }, "locus": { "chromosome": "23", "start_pos": 4464793, "end_pos": 4461169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035747.1", "url": "https://www.ensembl.org/id/ENSGALT00010035747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020727.1", "url": "https://www.ensembl.org/id/ENSGALP00010020727.1" } ] } }, { "isoform_ac": "A0A8V0YQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ00/entry", "sequence": { "sequence": "MLGSPDRRNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 174, "header": "tr|A0A8V0YQ00-1|A0A8V0YQ00_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=3 SV=1 CANONICAL=A0A8V0YPZ1-1" }, "locus": { "chromosome": "23", "start_pos": 4464793, "end_pos": 4452124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035762.1", "url": "https://www.ensembl.org/id/ENSGALT00010035762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020737.1", "url": "https://www.ensembl.org/id/ENSGALP00010020737.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H9W6-1", "protein_name": "Trafficking protein particle complex subunit", "gene_name": "Trappc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDSHSSLIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFLRRIEDNLPAGEE", "length": 180 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O43617-1", "protein_name": "Trafficking protein particle complex subunit 3", "gene_name": "TRAPPC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGFNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "length": 180 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55013-1", "protein_name": "Trafficking protein particle complex subunit 3", "gene_name": "Trappc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "length": 180 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P36149-1", "protein_name": "Trafficking protein particle complex subunit BET3", "gene_name": "BET3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQDYERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNITPNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCDVWFVSDILRGDSQTEIKVKLNRILKDEIPIGED", "length": 193 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5U1Z2-1", "protein_name": "Trafficking protein particle complex subunit 3", "gene_name": "Trappc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE", "length": 180 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86K94-1", "protein_name": "Trafficking protein particle complex subunit 3", "gene_name": "trappc3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKKYDKLGNDVFNKVEKINSELFTLTYGALVTQLIKDYEDIEQVNIKLEQMGYNIGIRLIEEFLAKSGIGRCSDFIETAEVIAKVGFKMFLGVNAHVGDWDANRKEFHLTIEDNPLIDFVELPDQYKHKLYYSNILCGVMRGALEMVQMKVKCTFVKCTLSDDSTSEIKVVLEEVLSDMIPVGYD", "length": 186 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FFV2-1", "protein_name": "Trafficking protein particle complex subunit", "gene_name": "TRAPPC3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPVGPRSGDAIFSSIDRVNAELFTLTYGAIVRQLLTDLEEVEEVNKQLDQMGYNIGIRLIDEFLAKSGVSRCVDFKETAEMIAKVGFKMFLGVTASVTSWDSDGTCCSIILEDNPLVDFVELPDTCQGLYYCNVLSGVIRGALEMVSMKTEVTWTRDVLRGDDAYELQVKLLKQVAEEYPYKDDE", "length": 186 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VSY8-1", "protein_name": "Trafficking protein particle complex subunit", "gene_name": "Bet3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRQASRLDAKKVNSEFLTLTYGALVTQMLRDFENAEDVNKQLERIGYNMGMRLIEDFLARTSAPRCLEMRETADRIQQAFRIYLNIQPTISNWSPASDEFSLVFDSNPLTEFVELPPDLTNLRYSAILSGCIRGALEMVQLEVQCWFVQDQLKGDNVTELRVKFVRRLEEVIPAGED", "length": 178 }, "evidence": [ { "id": "A0A8V0YPZ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPZ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMY4-1", "uniprot_ac": "A0A8V0YMY4", "uniprot_id": "A0A8V0YMY4_CHICK", "mass": { "chemical_mass": 82220.0, "monoisotopic_mass": 82220.0 }, "refseq": {}, "gene_names": [ { "name": "SLC44A1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ] } ], "protein_names": [ { "name": "Choline transporter-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Choline transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U280", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U280#function" }, { "database": "UniProtKB", "id": "RU368066", "url": "https://www.uniprot.org/uniprotkb/RU368066#function" }, { "database": "UniProtKB", "id": "A0A8V0YGR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR3#function" }, { "database": "UniProtKB", "id": "A0A8V0YN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN35#function" }, { "database": "UniProtKB", "id": "A0A8V0YPX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX8#function" }, { "database": "UniProtKB", "id": "A0A8V0YGQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ8#function" }, { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4#function" }, { "database": "UniProtKB", "id": "A0A8V0YPW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW3#function" }, { "database": "UniProtKB", "id": "A0A8V0YPX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC44A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4", "locus": { "chromosome": "Z", "start_pos": 55675286, "end_pos": 55605799, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014184", "url": "https://www.ensembl.org/id/ENSGALG00010014184" } ] } } ], "crossref": [ { "id": "A0A8V0YMY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015439", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015439", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427301", "url": "https://www.ncbi.nlm.nih.gov/gene/427301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427301", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427301", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U280", "url": "https://www.orthodb.org/?gene=A0A3Q2U280", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YGQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGR3", "url": "https://www.orthodb.org/?gene=A0A8V0YGR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMY4", "url": "https://www.orthodb.org/?gene=A0A8V0YMY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN35", "url": "https://www.orthodb.org/?gene=A0A8V0YN35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPW3", "url": "https://www.orthodb.org/?gene=A0A8V0YPW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPX3", "url": "https://www.orthodb.org/?gene=A0A8V0YPX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPX8", "url": "https://www.orthodb.org/?gene=A0A8V0YPX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U280", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U280", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U280-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U280-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMAREQMLEASGAVESRVSQVENNSQNLHSKENSHSISQTSHSNVPCALLLFCSPEQERCNLTERNYFYTSDCVAGYSNCDKEKGRSSKQMLKA", "length": 735, "header": "tr|A0A8V0YMY4-1|A0A8V0YMY4_CHICK Isoform 1 of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U280-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U280/entry", "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMASGASSS", "length": 650, "header": "tr|A0A3Q2U280-1|A0A8V0YMY4_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55668577, "end_pos": 55605975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034148.1", "url": "https://www.ensembl.org/id/ENSGALT00010034148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020063.1", "url": "https://www.ensembl.org/id/ENSGALP00010020063.1" } ] } }, { "isoform_ac": "A0A8V0YGQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ8/entry", "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMITSLSYS", "length": 623, "header": "tr|A0A8V0YGQ8-1|A0A8V0YMY4_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55664883, "end_pos": 55605975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034134.1", "url": "https://www.ensembl.org/id/ENSGALT00010034134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020055.1", "url": "https://www.ensembl.org/id/ENSGALP00010020055.1" } ] } }, { "isoform_ac": "A0A8V0YGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR3/entry", "sequence": { "sequence": "MSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMASGASSS", "length": 642, "header": "tr|A0A8V0YGR3-1|A0A8V0YMY4_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55668577, "end_pos": 55606917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034143.1", "url": "https://www.ensembl.org/id/ENSGALT00010034143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020060.1", "url": "https://www.ensembl.org/id/ENSGALP00010020060.1" } ] } }, { "isoform_ac": "A0A8V0YMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4/entry", "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMAREQMLEASGAVESRVSQVENNSQNLHSKENSHSISQTSHSNVPCALLLFCSPEQERCNLTERNYFYTSDCVAGYSNCDKEKGRSSKQMLKA", "length": 735, "header": "tr|A0A8V0YMY4-1|A0A8V0YMY4_CHICK Isoform 1 of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55674859, "end_pos": 55605975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034162.1", "url": "https://www.ensembl.org/id/ENSGALT00010034162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020069.1", "url": "https://www.ensembl.org/id/ENSGALP00010020069.1" } ] } }, { "isoform_ac": "A0A8V0YN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN35/entry", "sequence": { "sequence": "MLWSLEWKKKSNLGRLSPLILFLKRAVLYAHTSISFSSPSIKTSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMASGASSS", "length": 684, "header": "tr|A0A8V0YN35-1|A0A8V0YN35_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55668577, "end_pos": 55624419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034126.1", "url": "https://www.ensembl.org/id/ENSGALT00010034126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020052.1", "url": "https://www.ensembl.org/id/ENSGALP00010020052.1" } ] } }, { "isoform_ac": "A0A8V0YPW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW3/entry", "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMTVNNASSMLPQPVLLMMCLLGRHCMSE", "length": 670, "header": "tr|A0A8V0YPW3-1|A0A8V0YPW3_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55667048, "end_pos": 55605975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034139.1", "url": "https://www.ensembl.org/id/ENSGALT00010034139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020058.1", "url": "https://www.ensembl.org/id/ENSGALP00010020058.1" } ] } }, { "isoform_ac": "A0A8V0YPX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX3/entry", "sequence": { "sequence": "MFRNLLKLMDLPCVATNYCHQNILQTQGLPSCVLNILFQRVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMASGASSS", "length": 470, "header": "tr|A0A8V0YPX3-1|A0A8V0YPX3_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55668577, "end_pos": 55635136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034157.1", "url": "https://www.ensembl.org/id/ENSGALT00010034157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020068.1", "url": "https://www.ensembl.org/id/ENSGALP00010020068.1" } ] } }, { "isoform_ac": "A0A8V0YPX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX8/entry", "sequence": { "sequence": "MGCCSSAAQSSKREWKPLEDHSCTDVPWLLLFILFCIGMGFICGFTIATGAAARLLSGYDSYGNICGQKNVKVEGIVNSGLDLTQKKYVFFLDPCNIDLVHQKIKSLALCVSACPRKELKTLADVQKFAETNGSTLCSYELLPSEYTTDPRAAKLCPKYPVPESAPIPFFHRCAPVNISCYAKFAEALITFVSDSSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKERMSASTVETQIAKENLQALLIYAISATVFTVILLLIMLIMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFVLILFWTYWTTVLLFLGTTGNPVPNEEGFVEFRVAGPLKYMWWYHLVGLIWISEFILACQQMTVAGAVVTYYFTREKRNLPFTPILASVNRLVCYHLGTVAKGSFIITLVKIPRMILMYIHTQLKGKENACARCMLKACICCLWCLEKCLTYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQRDYTTWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKSMREAGRGGGAEGRELKPMAREQMLEASGAVESRVSQSKKGVILRKGIIFILRIVLLVTVTVIRRKEDLPNKC", "length": 697, "header": "tr|A0A8V0YPX8-1|A0A8V0YPX8_CHICK Computationally mapped isoform of Choline transporter-like protein OS=Gallus gallus OX=9031 GN=SLC44A1 PE=1 SV=1 CANONICAL=A0A8V0YMY4-1" }, "locus": { "chromosome": "Z", "start_pos": 55674851, "end_pos": 55605975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034172.1", "url": "https://www.ensembl.org/id/ENSGALT00010034172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020073.1", "url": "https://www.ensembl.org/id/ENSGALP00010020073.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427301", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427301", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-GGA-6798163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798163", "resource": "Reactome", "description": "Choline catabolism" }, { "id": "R-GGA-9958517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958517", "resource": "Reactome", "description": "SLC-mediated bile acid transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" }, { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" }, { "name": "ethanolamine transmembrane transporter activity", "id": "GO:0034228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" }, { "name": "choline transport", "id": "GO:0015871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 702, "end_pos": 704 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YME5-1", "uniprot_ac": "A0A8V0YME5", "uniprot_id": "A0A8V0YME5_CHICK", "mass": { "chemical_mass": 301309.0, "monoisotopic_mass": 301309.0 }, "refseq": { "ac": "XP_025000317", "name": "nipped-B homolog-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" }, "gene_names": [ { "name": "LOC427025", "type": "recommended", "evidence": [ { "id": "A0A8V0YME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ] }, { "name": "LOC427025", "type": "synonym", "evidence": [ { "id": "XP_025000317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] }, { "name": "NIPBLL", "type": "synonym", "evidence": [ { "id": "XP_025000317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] }, { "name": "NIPBL", "type": "synonym", "evidence": [ { "id": "XP_025000317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] }, { "name": "SCC2W", "type": "synonym", "evidence": [ { "id": "XP_025000317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] } ], "protein_names": [ { "name": "Nipped-B protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5/entry#names_and_taxonomy" } ] }, { "name": "nipped-B homolog-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025000317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427025", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000039023", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039023", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427025", "url": "https://www.ncbi.nlm.nih.gov/gene/427025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAU6", "url": "https://www.orthodb.org/?gene=A0A3Q2UAU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YME5", "url": "https://www.orthodb.org/?gene=A0A8V0YME5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21704:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21704:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025000317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAU6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAILARNPNVFREKSMQTRYGVQSGMLMSSQFNISQNPMRGSTASSSYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYVPYSHPPSYTPHPQLQQASVSSPIITAGMRNLHESKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSEDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLCGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNTAQCLPQHEQTVFLQAQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGAITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGTTGGNRPTSQETCSAGNGARPPLMVSIDLQQAGRADSQATSTQDLDAFKKKEEIKQYNDGFVSFPQEDTVGIKLKPENHPEIFRKKADFGGQKTSIQQNENKQMEFQQNESRRLESKLNENKQIEAKYESKHESSQIEPKQNENRQTESKQNESREMEIKPNEGKQNNGKQEIRQRPEMPKQKTEGRPEIPKHRHDSRRDSSKPLSDKKIEISRHKTDVKSDPSKIKCESRSDSVKQRPDGRSVSDTLRCDHVNLKQRSEDRGESERYRGDPIKIRRPEYLRSSNKNEHDSKHGIKSDVSKTEKFERKHRHESGESRERFSSGDQKSRPDSLRIKQESKGDCSKSRPDKPGFKSPNSKDERRIDGNKSKVDSNKIHTGNKAEFPSYLLGARSGTLKHFVIPKIKRDKDGNVTQESRKTECKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRYKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDMDDYSPPPSLSEVARKIKKKEKQKKRKAYEPKLTPEEMLDSSTFKRFSASIENILENLEDLDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGVLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSEEESNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQVSGGEDEIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIITTAASQFSTLKINSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENTIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDYSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKDMNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMAVVQHCVSCLGAVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTVLTANKPALLRSLFTVGALCRHFDFDQEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKSLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCTKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKESKPSSDEEAESDSGSESESEEEACKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKAGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNSAAETEDDESDGEDRGGGTSGVRRRRSQRISQRITH", "length": 2663, "header": "tr|A0A8V0YME5-1|A0A8V0YME5_CHICK Isoform 1 of Nipped-B protein OS=Gallus gallus OX=9031 GN=LOC427025 PE=3 SV=1 CANONICAL=A0A8V0YME5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UAU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAU6/entry", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAILARNPNVFREKSMQTRYGVQSGMLMSSQFNISQNPMRGSTASSSYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYVPYSHPPSYTPHPQLQQASVSSPIITAGMRNLHESKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSEDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKDKPLKKRKQENKPQEAGGTTGGNRPTSQETCSAGNGARPPLMVSIDLQQAGRADSQATSTQDLDAFKKKEEIKQYNDGFVSFPQEDTVGIKLKPENHPEIFRKKADFGGQKTSIQQNENKQMEFQQNESRRLESKLNENKQIEAKYESKHESSQIEPKQNENRQTESKQNESREMEIKPNEGKQNNGKQEIRQRPEMPKQKTEGRPEIPKHRHDSRRDSSKPLSDKKIEISRHKTDVKSDPSKIKCESRSDSVKQRPDGRSVSDTLRCDHVNLKQRSEDRGESERYRGDPIKIRRPEYLRSSNKNEHDSKHGIKSDVSKTEKFERKHRHESGESRERFSSGDQKSRPDSLRIKQESKGDCSKSRPDKPGFKSPNSKDERRIDGNKSKVDSNKIHTGNKAEFPSYLLGARSGTLKHFVIPKIKRDKDGNVTQESRKTECKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRYKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDMDDYSPPPSLSEVARKIKKKEKQKKRKAYEPKLTPEEMLDSSTFKRFSASIENILENLEDLDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGVLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSEEESNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQVSGGEDEIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIITTAASQFSTLKINSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENTIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDYSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKDMNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMAVVQHCVSCLGAVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTVLTANKPALLRSLFTVGALCRHFDFDQEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKSLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCTKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKESKPSSDEEAESDSGSESESEEEACKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKAGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNSAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELASQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2559, "header": "tr|A0A3Q2UAU6-1|A0A8V0YME5_CHICK Computationally mapped isoform of Nipped-B protein OS=Gallus gallus OX=9031 GN=LOC427025 PE=3 SV=1 CANONICAL=A0A8V0YME5-1" }, "locus": { "chromosome": "W", "start_pos": 5481698, "end_pos": 5365344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029687.1", "url": "https://www.ensembl.org/id/ENSGALT00010029687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017274.1", "url": "https://www.ensembl.org/id/ENSGALP00010017274.1" } ] } }, { "isoform_ac": "A0A8V0YME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5/entry", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAILARNPNVFREKSMQTRYGVQSGMLMSSQFNISQNPMRGSTASSSYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYVPYSHPPSYTPHPQLQQASVSSPIITAGMRNLHESKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSEDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLCGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNTAQCLPQHEQTVFLQAQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGAITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGTTGGNRPTSQETCSAGNGARPPLMVSIDLQQAGRADSQATSTQDLDAFKKKEEIKQYNDGFVSFPQEDTVGIKLKPENHPEIFRKKADFGGQKTSIQQNENKQMEFQQNESRRLESKLNENKQIEAKYESKHESSQIEPKQNENRQTESKQNESREMEIKPNEGKQNNGKQEIRQRPEMPKQKTEGRPEIPKHRHDSRRDSSKPLSDKKIEISRHKTDVKSDPSKIKCESRSDSVKQRPDGRSVSDTLRCDHVNLKQRSEDRGESERYRGDPIKIRRPEYLRSSNKNEHDSKHGIKSDVSKTEKFERKHRHESGESRERFSSGDQKSRPDSLRIKQESKGDCSKSRPDKPGFKSPNSKDERRIDGNKSKVDSNKIHTGNKAEFPSYLLGARSGTLKHFVIPKIKRDKDGNVTQESRKTECKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRYKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDMDDYSPPPSLSEVARKIKKKEKQKKRKAYEPKLTPEEMLDSSTFKRFSASIENILENLEDLDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGVLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSEEESNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQVSGGEDEIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIITTAASQFSTLKINSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENTIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDYSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKDMNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMAVVQHCVSCLGAVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTVLTANKPALLRSLFTVGALCRHFDFDQEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKSLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCTKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKESKPSSDEEAESDSGSESESEEEACKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKAGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNSAAETEDDESDGEDRGGGTSGVRRRRSQRISQRITH", "length": 2663, "header": "tr|A0A8V0YME5-1|A0A8V0YME5_CHICK Isoform 1 of Nipped-B protein OS=Gallus gallus OX=9031 GN=LOC427025 PE=3 SV=1 CANONICAL=A0A8V0YME5-1" }, "locus": { "chromosome": "W", "start_pos": 5481339, "end_pos": 5365344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029694.1", "url": "https://www.ensembl.org/id/ENSGALT00010029694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017278.1", "url": "https://www.ensembl.org/id/ENSGALP00010017278.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "Scc2-Scc4 cohesin loading complex", "id": "GO:0090694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "embryonic organ morphogenesis", "id": "GO:0048562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048562", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cohesin loader activity", "id": "GO:0061775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1387, "end_pos": 1389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1437, "end_pos": 1439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1559, "end_pos": 1561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1868, "end_pos": 1870, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1893, "end_pos": 1895, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2090, "end_pos": 2092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2185, "end_pos": 2187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2504, "end_pos": 2506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" }, { "start_pos": 994, "end_pos": 996, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME5" }, { "id": "PF12830", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12830" } ], "ann_type": "Domain_Extent_Annotation", 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383, "end_pos": 385 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 884, "end_pos": 886 }, { "start_pos": 928, "end_pos": 930 }, { "start_pos": 994, "end_pos": 996 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"https://www.ncbi.nlm.nih.gov/protein/XP_015143207" } ] } ], "protein_names": [ { "name": "Spermatogenesis-defective protein 39 homolog", "type": "recommended", "evidence": [ { "id": "A0A1D5NXV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6/entry#names_and_taxonomy" } ] }, { "name": "VPS33B-interacting protein in apical-basolateral polarity regulator", "type": "synonym", "evidence": [ { "id": "A0A1D5NXV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6/entry#names_and_taxonomy" } ] }, { "name": "VPS33B-interacting protein in polarity and apical restriction", "type": "synonym", "evidence": [ { "id": "A0A1D5NXV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-defective protein 39 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143207" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VIPAS39", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6", "locus": { "chromosome": "5", "start_pos": 38728302, "end_pos": 38739912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005329", "url": "https://www.ensembl.org/id/ENSGALG00010005329" } ] } } ], "crossref": [ { "id": "A0A1D5NXV6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010459", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423377", "url": "https://www.ncbi.nlm.nih.gov/gene/423377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423377", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423377", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEMVIEC", "url": "https://omabrowser.org/oma/group/PEMVIEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXV6", "url": "https://www.orthodb.org/?gene=A0A1D5NXV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGE4", "url": "https://www.orthodb.org/?gene=A0A8V0XGE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMY8", "url": "https://www.orthodb.org/?gene=A0A8V0XMY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQP5", "url": "https://www.orthodb.org/?gene=A0A8V0XQP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13364:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13364:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015143207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRARADEEEYWHSSKFRAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDLEKVSWSGEPVGSISWSIKETASSSSSSLEGRDTSLQKGSSSYAALPKQVSSYSLSSLFKGRNRLPSLPSLSDAFSDTGVKNYAPELRRPRAEYKDYSNDWSPRDTVRRMQRGKVCSLERFRSLQDKMVLLDEAVAGHDGNVITAVLIFLKRTLRREVLFRELEVRQVALCHLIHFLKETGEQKLLLDLLRFLDRTEEVALSQYREHLNIQDVEKKREFLKGCIGLPFSAEDISHIQDHYTLLERQIIIETNDRHLAMAGQSEIFRKYPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPTNLKKTFKIPDKQYVLTALAARAKLRAWEDVDALLTTKNWLGYTKKKAPIGFHRVVEILQRNNAPVQVLQEYVRLVEDVETRLNLATKYKCHDVVIDTYRDLKDRIQLMAYKCKVERGSAEEEKINSLLSNMQIRWKN", "length": 491, "header": "tr|A0A1D5NXV6-1|A0A1D5NXV6_CHICK Isoform 1 of Spermatogenesis-defective protein 39 homolog OS=Gallus gallus OX=9031 GN=VIPAS39 PE=1 SV=2 CANONICAL=A0A1D5NXV6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6/entry", "sequence": { "sequence": "MSRARADEEEYWHSSKFRAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDLEKVSWSGEPVGSISWSIKETASSSSSSLEGRDTSLQKGSSSYAALPKQVSSYSLSSLFKGRNRLPSLPSLSDAFSDTGVKNYAPELRRPRAEYKDYSNDWSPRDTVRRMQRGKVCSLERFRSLQDKMVLLDEAVAGHDGNVITAVLIFLKRTLRREVLFRELEVRQVALCHLIHFLKETGEQKLLLDLLRFLDRTEEVALSQYREHLNIQDVEKKREFLKGCIGLPFSAEDISHIQDHYTLLERQIIIETNDRHLAMAGQSEIFRKYPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPTNLKKTFKIPDKQYVLTALAARAKLRAWEDVDALLTTKNWLGYTKKKAPIGFHRVVEILQRNNAPVQVLQEYVRLVEDVETRLNLATKYKCHDVVIDTYRDLKDRIQLMAYKCKVERGSAEEEKINSLLSNMQIRWKN", "length": 491, "header": "tr|A0A1D5NXV6-1|A0A1D5NXV6_CHICK Isoform 1 of Spermatogenesis-defective protein 39 homolog OS=Gallus gallus OX=9031 GN=VIPAS39 PE=1 SV=2 CANONICAL=A0A1D5NXV6-1" }, "locus": { "chromosome": "5", "start_pos": 38739886, "end_pos": 38729162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012645.1", "url": "https://www.ensembl.org/id/ENSGALT00010012645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007209.1", "url": "https://www.ensembl.org/id/ENSGALP00010007209.1" } ] } }, { "isoform_ac": "A0A8V0XGE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGE4/entry", "sequence": { "sequence": "MSRARADEEEYWHSSKFRAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDLEKVSWSGEPVGSISWSIKETASSSSSSLEGRDTSLQKGSSSYAALPKQVSSYSLSSLFKAFSDTGVKNYAPELRRPRAEYKDYSNDWSPRDTVRRMQRGKVCSLERFRSLQDKMVLLDEAVAGHDGNVITAVLIFLKRTLRREVLFRELEVRQVALCHLIHFLKETGEQKLLLDLLRFLDRTEEVALSQYREHLNIQDVEKKREFLKGCIGLPFSAEDISHIQDHYTLLERQIIIETNDRHLAMAGQSEIFRKYPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPTNLKKTFKIPDKQYVLTALAARAKLRAWEDVDALLTTKNWLGYTKKKAPIGFHRVVEILQRNNAPVQVLQEYVRLVEDVETRLNLATKYKCHDVVIDTYRDLKDRIQLMAYKCKVERGSAEEEKINSLLSNMQIRWKN", "length": 478, "header": "tr|A0A8V0XGE4-1|A0A1D5NXV6_CHICK Computationally mapped isoform of Spermatogenesis-defective protein 39 homolog OS=Gallus gallus OX=9031 GN=VIPAS39 PE=1 SV=1 CANONICAL=A0A1D5NXV6-1" }, "locus": { "chromosome": "5", "start_pos": 38739886, "end_pos": 38729162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012646.1", "url": "https://www.ensembl.org/id/ENSGALT00010012646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007210.1", "url": "https://www.ensembl.org/id/ENSGALP00010007210.1" } ] } }, { "isoform_ac": "A0A8V0XMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMY8/entry", "sequence": { "sequence": "MSRARADEEEYWHSSKFRAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDLEKVSWSGEPVGRRNRLPSLPSLSDAFSDTGVKNYAPELRRPRAEYKDYSNDWSPRDTVRRMQRGKVCSLERFRSLQDKMVLLDEAVAGHDGNVITAVLIFLKRTLRREVLFRELEVRQVALCHLIHFLKETGEQKLLLDLLRFLDRTEEVALSQYREHLNIQDVEKKREFLKGCIGLPFSAEDISHIQDHYTLLERQIIIETNDRHLAMAGQSEIFRKYPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPTNLKKTFKIPDKQYVLTALAARAKLRAWEDVDALLTTKNWLGYTKKKAPIGFHRVVEILQRNNAPVQVLQEYVRLVEDVETRLNLATKYKCHDVVIDTYRDLKDRIQLMAYKCKVERGSAEEEKINSLLSNMQIRWKN", "length": 443, "header": "tr|A0A8V0XMY8-1|A0A1D5NXV6_CHICK Computationally mapped isoform of Spermatogenesis-defective protein 39 homolog OS=Gallus gallus OX=9031 GN=VIPAS39 PE=1 SV=1 CANONICAL=A0A1D5NXV6-1" }, "locus": { "chromosome": "5", "start_pos": 38739886, "end_pos": 38729162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012648.1", "url": "https://www.ensembl.org/id/ENSGALT00010012648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007212.1", "url": "https://www.ensembl.org/id/ENSGALP00010007212.1" } ] } }, { "isoform_ac": "A0A8V0XQP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQP5/entry", "sequence": { "sequence": "MSRARADEEEYWHSSKFRAFTFDDEDDELSQVGAEPPPRPALWGRGPTLVCAQTVFFPQLKESKRAVNSLRDIVDDDDDDLEKVSWSGEPVGSISWSIKETASSSSSSLEGRDTSLQKGSSSYAALPKQVSSYSLSSLFKGRNRLPSLPSLSDAFSDTGVKNYAPELRRPRAEYKDYSNDWSPRDTVRRMQRGKVCSLERFRSLQDKMVLLDEAVAGHDGNVITAVLIFLKRTLRREVLFRELEVRQVALCHLIHFLKETGEQKLLLDLLRFLDRTEEVALSQYREHLNIQDVEKKREFLKGCIGLPFSAEDISHIQDHYTLLERQIIIETNDRHLAMAGQSEIFRKYPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPTNLKKTFKIPDKQYVLTALAARAKLRAWEDVDALLTTKNWLGYTKKKAPIGFHRVVEILQRNNAPVQVLQEYVRLVEDVETRLNLATKYKCHDVVIDTYRDLKDRIQLMAYKCKVERGSAEEEKINSLLSNMQIRWKN", "length": 519, "header": "tr|A0A8V0XQP5-1|A0A1D5NXV6_CHICK Computationally mapped isoform of Spermatogenesis-defective protein 39 homolog OS=Gallus gallus OX=9031 GN=VIPAS39 PE=1 SV=1 CANONICAL=A0A1D5NXV6-1" }, "locus": { "chromosome": "5", "start_pos": 38739886, "end_pos": 38729162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012649.1", "url": "https://www.ensembl.org/id/ENSGALT00010012649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007213.1", "url": "https://www.ensembl.org/id/ENSGALP00010007213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423377", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423377", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BSI0-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "VIPAS39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMKMMSSHSSRTPSLLFCEVRSGDCLSALPSVCLQLKESKRAVNSLRDFVDDDDDDDLERVSWSGEPVGSISWSIKETAGNSVSNHEREQLKSRNSFSSYTPLPKPASTYSLSSFFRGRTRPGSFQSLSDALSDAPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWHDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDAVLNSSQIRWKN", "length": 496 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5D796-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "VIPAS39", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDEDDLERVSWTGEPVGSISWSIKETAGNSGSSHEREQLKNRNSFSTYAQLPKPASTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKDKIQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLELAGQTEVFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWHDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQVLQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDALLNSSQIRWKN", "length": 481 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H639-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "Vipas39", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWTGEPVGSISWSIKETAGTSGSAPEGREQLKGRNSFYTQLPKPTSTYSLSSFFKGRTRPGSFQSLSDALSDTPPKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRRGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHFIHFLKETGDQKLLLDLFRFLDRTEELALTHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHVQDHYTLLERQIIIEANDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPINLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQDYVNLVEDVDTKLNLATKLKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSVEEEKIDAILNSSQIRWKN", "length": 491 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5PQN6-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "Vipas39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWTGEPVGSISWSIKETAGSSGSTSEGREQMKGRNSFYTQLPKPPSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKTYSPELGRPKGEYRDYSNDWSLSDTVRRLRQGKVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHVQDQYTLLERQIIIEANDRHLESSGQTEIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPVNLKKTFKIPDRQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDVILSSSQIRWKN", "length": 460 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGQ1-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "Vipas39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDIVDDDDDDDLERVSWTGEPVGSISWSIKETAGSSGSTPEGREQLKGRNSFYTQLPKPPSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSLSDTVQRLRRGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRAEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDAAHVQDHYTLLERQIIIEANDRHLESSGQTDIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPINLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDAILSSSQIRWKN", "length": 491 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9C1-1", "protein_name": "Spermatogenesis-defective protein 39 homolog", "gene_name": "VIPAS39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWSGEPVGSISWSIRETAGNSGSTHEGREQLKSRNSFSSYAQLPKPTSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPDKRKEFLKTCVGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNNAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKDRQQLLAYRSKVDKGSAEEEKIDALLSSSQIRWKN", "length": 493 }, "evidence": [ { "id": "A0A1D5NXV6", "url": "https://omabrowser.org/oma/group/A0A1D5NXV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXV6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P3H0-1", "uniprot_ac": "A0A1D5P3H0", "uniprot_id": "A0A1D5P3H0_CHICK", "mass": { "chemical_mass": 19526.0, "monoisotopic_mass": 19526.0 }, "refseq": { "ac": "NP_001264068", "name": "M-phase phosphoprotein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264068" }, "gene_names": [ { "name": "MPHOSPH6", "type": "recommended", "evidence": [ { "id": "A0A1D5P3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0" } ] }, { "name": "MPHOSPH6", "type": "synonym", "evidence": [ { "id": "NP_001264068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264068" } ] } ], "protein_names": [ { "name": "M-phase phosphoprotein 6", "type": "synonym", "evidence": [ { "id": "NP_001264068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264068" }, { "id": "A0A1D5P3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01090395.1, BX935551.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Mar 14, 2013 this sequence version replaced XP_414172.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264068" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPHOSPH6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0", "locus": { "chromosome": "11", "start_pos": 15444148, "end_pos": 15467377, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007500", "url": "https://www.ensembl.org/id/ENSGALG00010007500" } ] } } ], "crossref": [ { "id": "A0A1D5P3H0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P3H0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031983", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415811", "url": "https://www.ncbi.nlm.nih.gov/gene/415811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415811", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSMKKKF", "url": "https://omabrowser.org/oma/group/GSMKKKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3H0", "url": "https://www.orthodb.org/?gene=A0A1D5P3H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XNS1", "url": "https://www.orthodb.org/?gene=A0A8V0XNS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV16", "url": "https://www.orthodb.org/?gene=A0A8V0XV16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXU2", "url": "https://www.orthodb.org/?gene=A0A8V0XXU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y0V3", "url": "https://www.orthodb.org/?gene=A0A8V0Y0V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13582:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13582:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10175", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10175", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"length": 164, "header": "tr|A0A1D5P3H0-1|A0A1D5P3H0_CHICK Isoform 1 of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0/entry", "sequence": { "sequence": "MAGEVKTKLSKNLLRMKFMQRGLDSQTKKQLDEEEKKIISDEHWYLDLPDLKEKESYIIEERSFIPCEDLLYGRMSFKGFNPEIEKLMVQINSKSKKEEIEEDDKMEADVSDEEMARRYETLVGTIGKKFLKKRDQRVLHDEDEEENSNTKPKKARKMFLKPQD", "length": 164, "header": "tr|A0A1D5P3H0-1|A0A1D5P3H0_CHICK Isoform 1 of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "locus": { "chromosome": "11", "start_pos": 15454040, "end_pos": 15447762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017888.1", "url": "https://www.ensembl.org/id/ENSGALT00010017888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009847.1", "url": "https://www.ensembl.org/id/ENSGALP00010009847.1" } ] } }, { "isoform_ac": "A0A8V0XNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNS1/entry", "sequence": { "sequence": "MAGEVKTKLSKNLLRMKFMQRGLDSQTKKQLDEEEKKIISDEHWYLDLPDLKEKESYIIEERSFIPCEDLLYGRMSFKGFNPEIEKLMVQINSKSKKEEIEEDDKMEADVSDEEMARRYETLVGTIGKKFLKKRDQRVLHDEDEEENTCNKGIRSNARTQTSWPLVSALEN", "length": 171, "header": "tr|A0A8V0XNS1-1|A0A1D5P3H0_CHICK Computationally mapped isoform of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "locus": { "chromosome": "11", "start_pos": 15454040, "end_pos": 15446751, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017876.1", "url": "https://www.ensembl.org/id/ENSGALT00010017876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009843.1", "url": "https://www.ensembl.org/id/ENSGALP00010009843.1" } ] } }, { "isoform_ac": "A0A8V0XV16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV16/entry", "sequence": { "sequence": "MFKRQMSPSGVICQPAGLVKCGNDAAYVGEFMQRGLDSQTKKQLDEEEKKIISDEHWYLDLPDLKEKESYIIEERSFIPCEDLLYGRMSFKGFNPEIEKLMVQINSKSKKEEIEEDDKMEADVSDEEMARRYETLVGTIGKKFLKKRDQRVLHDEDEEENSNTKPKKARKMFLKPQD", "length": 177, "header": "tr|A0A8V0XV16-1|A0A1D5P3H0_CHICK Computationally mapped isoform of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "locus": { "chromosome": "11", "start_pos": 15451699, "end_pos": 15447762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017883.1", "url": "https://www.ensembl.org/id/ENSGALT00010017883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009845.1", "url": "https://www.ensembl.org/id/ENSGALP00010009845.1" } ] } }, { "isoform_ac": "A0A8V0XXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXU2/entry", "sequence": { "sequence": "MIPAVSCSSHGCYRCPGYGLGPAATPRCQQPARNAEGGATPPPPPPASPPPACAAAALRERGDPARPTGSAAAAMAGEVKTKLSKNLLRMKFMQRGLDSQTKKQLDEEEKKIISDEHWYLDLPDLKEKESYIIEERSFIPCEDLLYGRMSFKGFNPEIEKLMVQINSKSKKEEIEEDDKMEADVSDEEMARRYETLVGTIGKKFLKKRDQRVLHDEDEEENSNTKPKKARKMFLKPQD", "length": 238, "header": "tr|A0A8V0XXU2-1|A0A1D5P3H0_CHICK Computationally mapped isoform of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "locus": { "chromosome": "11", "start_pos": 15467318, "end_pos": 15447762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017896.1", "url": "https://www.ensembl.org/id/ENSGALT00010017896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009851.1", "url": "https://www.ensembl.org/id/ENSGALP00010009851.1" } ] } }, { "isoform_ac": "A0A8V0Y0V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0V3/entry", "sequence": { "sequence": "MDVIAFMQRGLDSQTKKQLDEEEKKIISDEHWYLDLPDLKEKESYIIEERSFIPCEDLLYGRMSFKGFNPEIEKLMVQINSKSKKEEIEEDDKMEADVSDEEMARRYETLVGTIGKKFLKKRDQRVLHDEDEEENSNTKPKKARKMFLKPQD", "length": 152, "header": "tr|A0A8V0Y0V3-1|A0A1D5P3H0_CHICK Computationally mapped isoform of M-phase phosphoprotein 6 OS=Gallus gallus OX=9031 GN=MPHOSPH6 PE=1 SV=1 CANONICAL=A0A1D5P3H0-1" }, "locus": { "chromosome": "11", "start_pos": 15467290, "end_pos": 15447762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017893.1", "url": "https://www.ensembl.org/id/ENSGALT00010017893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009849.1", "url": "https://www.ensembl.org/id/ENSGALP00010009849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415811", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AE22-1", "protein_name": "Uncharacterized protein", "gene_name": "MPHOSPH6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGEPRGGARRRTGLRMAAERKTKLSKNLLRMKFMQRGLDSETKKQLEEEEKKIISEEHWYLDLPELKEKESFIIEEQSFLLCEDLLYGRMSFRGFNPEVEKLMLQMNAKNKAEEVEDETVELDVSDEEMARRYETLVGTIGKKFAKKRDRANYEEDENGDIKPIKAKKMFLKPQD", "length": 176 }, "evidence": [ { "id": "A0A1D5P3H0", "url": "https://omabrowser.org/oma/group/A0A1D5P3H0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AL40-1", "protein_name": "M-phase phosphoprotein 6-like", "gene_name": "LOC134479437", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEWKTKLSTNLLLMKFMQRGLDSENQKQLEEEERKTIRNEHWYLDLPELKEKESFIIEDQSFSLCEDLLYGRMSFRGFNPEVEKFMLQMNSRNRAAAAEEETVEADVSEKEMARRYESLVGTIGKMFSKKRDRANDKEDENGNIKAIKTKKIFLKPQD", "length": 160 }, "evidence": [ { "id": "A0A1D5P3H0", "url": "https://omabrowser.org/oma/group/A0A1D5P3H0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99547-1", "protein_name": "M-phase phosphoprotein 6", "gene_name": "MPHOSPH6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAERKTRLSKNLLRMKFMQRGLDSETKKQLEEEEKKIISEEHWYLDLPELKEKESFIIEEQSFLLCEDLLYGRMSFRGFNPEVEKLMLQMNAKHKAEEVEDETVELDVSDEEMARRYETLVGTIGKKFARKRDHANYEEDENGDITPIKAKKMFLKPQD", "length": 160 }, "evidence": [ { "id": "A0A1D5P3H0", "url": "https://omabrowser.org/oma/group/A0A1D5P3H0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1Q1-1", "protein_name": "M-phase phosphoprotein 6", "gene_name": "Mphosph6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASERKTKLSKNLLRMKFMQRGLDSETKKQLEEEERKMISDEHWYLDLPELKEKESFIVEEQSFSLCEDLLYGRMSFRGFNPEVEKLMLQMNSKNRAEAAEEDETVEVDVSDEEMARRYETLVGTIGKKFVKKRDRANYEEDENGTIKAIKPKKMFLKPQD", "length": 161 }, "evidence": [ { "id": "A0A1D5P3H0", "url": "https://omabrowser.org/oma/group/A0A1D5P3H0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3H0" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3H0", "url": 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[], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUH1-1", "uniprot_ac": "A0A1D5NUH1", "uniprot_id": "A0A1D5NUH1_CHICK", "mass": { "chemical_mass": 32353.0, "monoisotopic_mass": 32353.0 }, "refseq": { "ac": "XP_424463", "name": "thioredoxin-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463" }, "gene_names": [ { "name": "TXNL1", "type": "recommended", "evidence": [ { "id": "A0A1D5NUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ] }, { "name": "TXNL1", "type": "synonym", "evidence": [ { "id": "XP_424463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463" } ] } ], "protein_names": [ { "name": "Thioredoxin-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5NUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1/entry#names_and_taxonomy" } ] }, { "name": "thioredoxin-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463" } ] }, { "annotation": "Active thioredoxin with a redox potential of about -250 mV.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1#function" }, { "database": "UniProtKB", "id": "ARBA00057161", "url": "https://www.uniprot.org/uniprotkb/ARBA00057161#function" }, { "database": "UniProtKB", "id": "A0A1D5P763", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P763#function" }, { "database": "UniProtKB", "id": "A0A8V0Y035", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y035#function" }, { "database": "UniProtKB", "id": "A0A8V0Y6A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6A8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TXNL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1", "locus": {} } ], "crossref": [ { "id": "A0A1D5NUH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033862", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426854", "url": "https://www.ncbi.nlm.nih.gov/gene/426854", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426854", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426854", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIFEMFP", "url": "https://omabrowser.org/oma/group/PIFEMFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUH1", "url": "https://www.orthodb.org/?gene=A0A1D5NUH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P763", "url": "https://www.orthodb.org/?gene=A0A1D5P763", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y035", "url": "https://www.orthodb.org/?gene=A0A8V0Y035", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6A8", "url": "https://www.orthodb.org/?gene=A0A8V0Y6A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P763", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P763", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P763-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P763-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y035", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y035", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y035-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y035-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGVKLIANDTEFQPELSAAGSRLAVVKFTMRGCGPCLRIAPAFNALSNKYPQATFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDSTYLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAERSEPTQALELTPDDIKEDGIIQLRYVKFQNVNSVTLFVQSNHGDEETTRITYFTFIGTPVQATNMNDFKRVVGKKGESH", "length": 289, "header": "tr|A0A1D5NUH1-1|A0A1D5NUH1_CHICK Isoform 1 of Thioredoxin-like protein 1 OS=Gallus gallus OX=9031 GN=TXNL1 PE=1 SV=1 CANONICAL=A0A1D5NUH1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1/entry", "sequence": { "sequence": "MVGVKLIANDTEFQPELSAAGSRLAVVKFTMRGCGPCLRIAPAFNALSNKYPQATFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDSTYLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAERSEPTQALELTPDDIKEDGIIQLRYVKFQNVNSVTLFVQSNHGDEETTRITYFTFIGTPVQATNMNDFKRVVGKKGESH", "length": 289, "header": "tr|A0A1D5NUH1-1|A0A1D5NUH1_CHICK Isoform 1 of Thioredoxin-like protein 1 OS=Gallus gallus OX=9031 GN=TXNL1 PE=1 SV=1 CANONICAL=A0A1D5NUH1-1" }, "locus": { "chromosome": "Z", "start_pos": 936285, "end_pos": 922040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024549.1", "url": "https://www.ensembl.org/id/ENSGALT00010024549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013929.1", "url": "https://www.ensembl.org/id/ENSGALP00010013929.1" } ] } }, { "isoform_ac": "A0A1D5P763-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P763/entry", "sequence": { "sequence": "MVGVKLIANDTEFQPELSAAGSRLAVVKFTMRGCGPCLRIAPAFNALSNKYPQATFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDSTYLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAERSEPTQALELTPDDIKEDGIIQLRYVKFQNVNSVTLFVQSNHGDEETTRITYFTFIGTPVQATNMNDFKRRNFPFLKN", "length": 288, "header": "tr|A0A1D5P763-1|A0A1D5P763_CHICK Computationally mapped isoform of Thioredoxin-like protein 1 OS=Gallus gallus OX=9031 GN=TXNL1 PE=1 SV=1 CANONICAL=A0A1D5NUH1-1" }, "locus": { "chromosome": "Z", "start_pos": 933589, "end_pos": 922040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024544.1", "url": "https://www.ensembl.org/id/ENSGALT00010024544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013925.1", "url": "https://www.ensembl.org/id/ENSGALP00010013925.1" } ] } }, { "isoform_ac": "A0A8V0Y035-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y035/entry", "sequence": { "sequence": "MVGVKLIANDTEFQPELSAAGSRLAVVKFTMRGCGPCLRIAPAFNALSNKYPQATFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDSTYLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAERSEPTQALELTPDDIKEDGIIQLRYVKFQNVNSVTLFVQSNHGDEETTRITYFTFIGTPVQATNMNDFKRIIHMGELSIPTSDWYCNTFH", "length": 300, "header": "tr|A0A8V0Y035-1|A0A1D5NUH1_CHICK Computationally mapped isoform of Thioredoxin-like protein 1 OS=Gallus gallus OX=9031 GN=TXNL1 PE=1 SV=1 CANONICAL=A0A1D5NUH1-1" }, "locus": { "chromosome": "Z", "start_pos": 934515, "end_pos": 922040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024537.1", "url": "https://www.ensembl.org/id/ENSGALT00010024537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013921.1", "url": "https://www.ensembl.org/id/ENSGALP00010013921.1" } ] } }, { "isoform_ac": "A0A8V0Y6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6A8/entry", "sequence": { "sequence": "MVGVKLIANDTEFQPELSAAGSRLAVVKFTMRGCGPCLRIAPAFNALSNKYPQATFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDSTYLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAERSEPTQALELTPDDIKEDGIIQLRYVKFQNVNSVTLFVQSNHGDEETTRITYFTFIGTPVQATNMNDFKRIIHMGELSIPTSDW", "length": 294, "header": "tr|A0A8V0Y6A8-1|A0A1D5NUH1_CHICK Computationally mapped isoform of Thioredoxin-like protein 1 OS=Gallus gallus OX=9031 GN=TXNL1 PE=1 SV=1 CANONICAL=A0A1D5NUH1-1" }, "locus": { "chromosome": "Z", "start_pos": 936259, "end_pos": 922040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024548.1", "url": "https://www.ensembl.org/id/ENSGALT00010024548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013928.1", "url": "https://www.ensembl.org/id/ENSGALP00010013928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426854", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426854", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-GGA-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SQ31-1", "protein_name": "Thioredoxin-like protein 1", "gene_name": "TXNL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDMTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRLEKKEKATKGTEDTGRPCCNQSYSSWIIA", "length": 309 }, "evidence": [ { "id": "A0A1D5NUH1", "url": "https://omabrowser.org/oma/group/A0A1D5NUH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43396-1", "protein_name": "Thioredoxin-like protein 1", "gene_name": "TXNL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "length": 289 }, "evidence": [ { "id": "A0A1D5NUH1", "url": "https://omabrowser.org/oma/group/A0A1D5NUH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDN6-1", "protein_name": "Thioredoxin-like protein 1", "gene_name": "Txnl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDADIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDMSFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTLFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "length": 289 }, "evidence": [ { "id": "A0A1D5NUH1", "url": "https://omabrowser.org/oma/group/A0A1D5NUH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920J4-1", "protein_name": "Thioredoxin-like protein 1", "gene_name": "Txnl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDLSFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTLFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH", "length": 289 }, "evidence": [ { "id": "A0A1D5NUH1", "url": "https://omabrowser.org/oma/group/A0A1D5NUH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VRP3-1", "protein_name": "Thioredoxin-like", "gene_name": "Txl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVRVINDESHFQAELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQEHIGTSGGEEGGEDYGQGLMELNTFISKQECECLNEADDHNLKHALASAGGYLQSDCDEQLILSITFNQAVKIHSLKFKAPSHLGPKDVKLFINQPRTIDFDMAESMNSVQDLSLAQKELESGVPVNLRYVKFQNVQNIQIFVKNNQSGGDVTQIDYIGFIGSPIMTTKMNDFKRVAGKKGESH", "length": 287 }, "evidence": [ { "id": "A0A1D5NUH1", "url": "https://omabrowser.org/oma/group/A0A1D5NUH1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155147" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIAM1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4", "locus": { "chromosome": "1", "start_pos": 104556127, "end_pos": 104672276, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011699", "url": "https://www.ensembl.org/id/ENSGALG00010011699" } ] } } ], "crossref": [ { "id": "ENSGALG00000015842", "url": 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"length": 1616, "header": "tr|A0A8V0Y5Z4-1|A0A1D5P0C4_CHICK Computationally mapped isoform of TIAM Rac1 associated GEF 1 OS=Gallus gallus OX=9031 GN=TIAM1 PE=3 SV=1 CANONICAL=A0A1D5P0C4-1" }, "locus": { "chromosome": "1", "start_pos": 104672077, "end_pos": 104557411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027997.1", "url": "https://www.ensembl.org/id/ENSGALT00010027997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016058.1", "url": "https://www.ensembl.org/id/ENSGALP00010016058.1" } ] } }, { "isoform_ac": "A0A8V0YED9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YED9/entry", "sequence": { "sequence": 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"MFVLLMMNDCEAMGNAESQNVEHAFYGDKHASLGRKHTSRSLRLSNKASRRTRHASSGKIIHRNSEVSTRSSSTPSIPQSLAENGLEPFTQEANLEDFGSPIWVDRVDMGLRPVSYHTDSSVTPSMDSSTVLTAASVQSMPDSEESRLYGEEPPFLAEGEGRLRRYAANGTRFVETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGLAEEKDVETAQGTEAECSPQQLVGCQRANSMSDLYSPKAPSAAVNGGPRNAFGGYCRNLVSDIPDIGSHKMASGAAEDAPSYSNYNTLPCRKSHCLSEGATNPQMSHSNSMQGRRAKTTQDVNVGEGSEFTDSGIEGAATDTDLLSRRSNATNSSYSPTASRAFIGSDSGSSSTGDGLRQGVYENFRRELEMSTTNSENMEEAGSALSDEQSSGTLSSPGQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYETDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTSSQTELENWITAIHSACATAVARQHHKEDTVKLLKTEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTILDQIFVWEQNLEQFQMDLFRYRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAARTGESGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKKQGRPSINQVFGEGVDSVKKSLEGIFDDTVPDGKREKEVALSSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVIRPGDTTRDVLEMICKTHQLDLSAHYLRLKFLIENQMQFYVPKQEEDIYELLYKEIEICQKITQHIQIEKSDTSSDIYGFSLSSVEEEGIRRLYVNGVKETGLAFKKGLKAGDEIVEINKKAAEDLDSALLKDVLIQPSLCLTVRTYPEIEEGQKLTQPPPRRLENPSDLSDSTLVFSGSNQGHSLCGDPDSSVETAPEEAEAQDLESSDEADKMSKSTEQVAAFCRSLHEMNPSDSSAHPQEFTGPQLATMRQLTDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTPDELDVLFGNLTEMVAFQVEFLKTLEDGVRLVPDLEKLEKVEQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPRRQHSSTLESYLIKPIQRILKYPLLLKELFALTDVDSEEHYHLDVAIKTMNKVASHINEMQKIHEEYGAVFDQLIAEQTGEKKEVADLSMGDLLLHNTVIWLNPPASLGKWKKEPELAAFVFKTAVVLVYKDGSKQKKKLGGSHRASIYEDWDPFRFRHMIPLEALQVRALASADAETNSVCEIVHVKSESEGRPERTFHLCCSSPEHRKDFLKAVHSILRDKHRRQLLKTESLPSSQQYVPFGGKRLCALKGARPAMNRAVSAPSKSLGRRRRRLARNRFTIDSDAVFTSSPEKEPQQPTHGGDTDRWVEEQFDLAQYEEQEDIKETDILSDDDEYCEAMRGSVADRDLRERLQAASITCRGDRSRPAMDTHASRMTQLKKQAALTGINGDVEGHGEEVIWVRREDFVPSRKLNTEL", "length": 1606, "header": "tr|A0A8V0YJ47-1|A0A1D5P0C4_CHICK Computationally mapped isoform of TIAM Rac1 associated GEF 1 OS=Gallus gallus OX=9031 GN=TIAM1 PE=3 SV=1 CANONICAL=A0A1D5P0C4-1" }, "locus": { "chromosome": "1", "start_pos": 104670285, "end_pos": 104557411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028009.1", "url": "https://www.ensembl.org/id/ENSGALT00010028009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016065.1", "url": "https://www.ensembl.org/id/ENSGALP00010016065.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418491", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-3928662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "resource": "Reactome", "description": "EPHB-mediated forward signaling" }, { "id": "R-GGA-3928665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928665", "resource": "Reactome", "description": "EPH-ephrin mediated repulsion of cells" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9958810", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958810", "resource": "Reactome", "description": "SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "regulation of epithelial to mesenchymal transition", "id": "GO:0010717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010717", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "non-canonical Wnt signaling pathway", "id": "GO:0035567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035567", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0C4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0C4" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYY2-1", "uniprot_ac": "A0A1D5NYY2", "uniprot_id": "A0A1D5NYY2_CHICK", "mass": { "chemical_mass": 164898.0, "monoisotopic_mass": 164898.0 }, "refseq": {}, "gene_names": [ { "name": "CLASP1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ] } ], "protein_names": [ { "name": "Cytoplasmic linker associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5NYY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLASP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2", "locus": { "chromosome": "7", "start_pos": 25701600, "end_pos": 25843880, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021749", "url": "https://www.ensembl.org/id/ENSGALG00010021749" } ] } } ], "crossref": [ { "id": "ENSGALG00000011645", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011645", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYY2", "url": "https://www.orthodb.org/?gene=A0A1D5NYY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK56", "url": "https://www.orthodb.org/?gene=A0A8V0ZK56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK62", "url": "https://www.orthodb.org/?gene=A0A8V0ZK62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK68", "url": "https://www.orthodb.org/?gene=A0A8V0ZK68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLV4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSL7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21567", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21567", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21567:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21567:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQPGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKTMHSWVGEDLPARTTTASSGPGEGNLEEKCKQAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1495, "header": "tr|A0A1D5NYY2-1|A0A1D5NYY2_CHICK Isoform 1 of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=2 CANONICAL=A0A1D5NYY2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQPGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKTMHSWVGEDLPARTTTASSGPGEGNLEEKCKQAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1495, "header": "tr|A0A1D5NYY2-1|A0A1D5NYY2_CHICK Isoform 1 of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=2 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052889.1", "url": "https://www.ensembl.org/id/ENSGALT00010052889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031795.1", "url": "https://www.ensembl.org/id/ENSGALP00010031795.1" } ] } }, { "isoform_ac": "A0A8V0ZK56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK56/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLDGTTTKTEGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSRFWGWSADGLSKHPPPLSQPNSIPTAPSHKTFRRSYSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1556, "header": "tr|A0A8V0ZK56-1|A0A1D5NYY2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=1 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052869.1", "url": "https://www.ensembl.org/id/ENSGALT00010052869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031774.1", "url": "https://www.ensembl.org/id/ENSGALP00010031774.1" } ] } }, { "isoform_ac": "A0A8V0ZK62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK62/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLASRRHSRSTSALSTADSVGQSDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1530, "header": "tr|A0A8V0ZK62-1|A0A1D5NYY2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=1 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052873.1", "url": "https://www.ensembl.org/id/ENSGALT00010052873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031779.1", "url": "https://www.ensembl.org/id/ENSGALP00010031779.1" } ] } }, { "isoform_ac": "A0A8V0ZK68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK68/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLASRRHSRSTSALSTADSVGQSDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1529, "header": "tr|A0A8V0ZK68-1|A0A1D5NYY2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=1 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052878.1", "url": "https://www.ensembl.org/id/ENSGALT00010052878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031784.1", "url": "https://www.ensembl.org/id/ENSGALP00010031784.1" } ] } }, { "isoform_ac": "A0A8V0ZLV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV4/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQPGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSRFWGWSADGLSKHPPPLSQPNSIPTAPSHKTFRRSYSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1503, "header": "tr|A0A8V0ZLV4-1|A0A1D5NYY2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=1 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052885.1", "url": "https://www.ensembl.org/id/ENSGALT00010052885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031791.1", "url": "https://www.ensembl.org/id/ENSGALP00010031791.1" } ] } }, { "isoform_ac": "A0A8V0ZSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSL7/entry", "sequence": { "sequence": "MEPSMEYCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKMVDGLATSWVNSSNYKVVLLGIDIISALVSRLQDRFKAQIGTVLPSLLDRLGDSKDSVREQDQTLLLKIMEQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQSLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSSSDKNFDDEDSVDGNRPSSANSSTSSKAPANSRRVGMGTTRRLGSAALGSKSSTGKEGAGAVDEEDFIKAFEDVPTVQIYSSRDLEESINKIREILSDDKHDWEQRVSALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKVMATSGVVAVRLIIRHTHIPRLIPIITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREADHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTPGSLQRSRSDVDVNAAASAKSKVTSSGASTPFSSAAALPPGSYASLGRIRTRRQSSGSATSVTSTPADTRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSSYGGLSSGTSRVQPVPSSSEKRSKIPRSQGCSRETSPNRIGLDRFGLGQSGRMPASVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSACSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLIGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTNVGSPSNTLGRTPSRHSSSRTSPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDMVSRDGGLAVPTSDVRGGSDTVEGGRMALDNKTSLLNTQPPRAFSGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDNLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQLLPDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEELKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS", "length": 1465, "header": "tr|A0A8V0ZSL7-1|A0A1D5NYY2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 1 OS=Gallus gallus OX=9031 GN=CLASP1 PE=1 SV=1 CANONICAL=A0A1D5NYY2-1" }, "locus": { "chromosome": "7", "start_pos": 25843664, "end_pos": 25701833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052892.1", "url": "https://www.ensembl.org/id/ENSGALT00010052892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031798.1", "url": "https://www.ensembl.org/id/ENSGALP00010031798.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "basal cortex", "id": "GO:0045180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045180", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYY2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYY2" } ], "pmid": "" }, { "name": "establishment of mitotic spindle localization", "id": "GO:0040001", "url": 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152776" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDI2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6", "locus": {} } ], "crossref": [ { "id": "A0A1D5NXK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040663", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040663", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01796", "url": 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI89", "url": "https://www.orthodb.org/?gene=A0A8V0ZI89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI94", "url": "https://www.orthodb.org/?gene=A0A8V0ZI94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15397", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15397", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15397:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15397:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152776", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI89-1", "url": 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"MLLTVFCLRRDRSELTFSLQVDADFELQNFRALCELESGIPAAESQIVYAERPLTDNNRSLASYGLKDGDVVILRQKDTVEPRPSIRFPALPRIDFSSIAVPGTSAQQRQSPAQRLRPSPPDAPSFSQGLENPALLREMLLANPHELSLLKERNPPLAEALLSGDLDKFTRVLLEQQQDRARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLEIGTTGSQTAFLPEGELPECARLAYGAGREDVRPEEIADQELAEAIQKSVEEAENSDKETTSLEMPSLPASDGFQNPVQSSGLSSKICNPTNQLLDRSIFSPVSTRLSKASLTEPIDPKAVKSFESSTECQITPEKDYPLVLQHLSNISSLANNDHSLQTEEVNCCSPACLSQNTLEETFLADSLMECNTIEQGCGEEPLLEVTKENSLTDSTTKLGQIKNASLPSELKEPKQKNKLTIKHQMYKEPEKFEHLEEQTDKTDLEHPGNIGGVEKPAVEEEGRTVSQPESPPAEMREGRLEKADLSCVKGHIQASCSCVHMEVDTAERSVAEVHISASKQKWQAKNGRALDLNSDASSMELESLKSATSLSDAASTSDVLQSKSTSEIPTKCNELSNLTSENSSSPSIIHQQDTDLCRHLEEPCFSLASALKELHKLLISCKGECKVLTSEVSQLEMVCKEQVQQKGFSEDERKGLDPDGQQQSSSSFNVRSEGGKKERSQPCNSGTENVSLESVTHMESASGEDAFEIPKFSGKSDLIVVTSAGKSDQQESSEQAKVLPEWFLSSTLEQSTVSSQPALDEGTSQDIQASLTRAPERSSSSAPDSPASLGGCEEPLPSPPAESTELSLVASPPAFSPADVDRILGAGFTTQEALEALEQADGNADLALLILLAKSIVVPT", 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"MLLTVFCLRRDRSELTFSLQVDADFELQNFRALCELESGIPAAESQIVYAERPLTDNNRSLASYGLKDGDVVILRQKDTVEPRPSIRFPALPRIDFSSIAVPGTSAQQRQSPAQRLRPSPPDAPSFSQGLENPALLREMLLANPHELSLLKERNPPLAEALLSGDLDKFTRVLLEQQQDRARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLEIGTTGSQTAFLPEGELPECARLAYGAGREDVRPEEIADQELAEAIQKSVEEAENSDKETTSLEMPSLPASDGFQNPVQSSGLSSKICNPTNQLLDRSIFSPVSTRLSKASLTEPIDPKAVKSFESSTECQITPEKDYPLVLQHLSNISSLANNDHSLQTEEVNCCSPACLSQNTLEETFLADSLMECNTIEQGCGEEPLLEVTKENSLTDSTTKLGQIKNASLPSELKEPKQKNKLTIKHQMYKEPEKFEHLEEQTDKTDLEHPGNIGGVEKPAVEEEGRTVSQPESPPAEMREGRLEKADLSCVKGHIQASCSCVHMEVDTAERSVAEVHISASKQKWQAKNGRALDLNSDASSMELESLKSATSLSDAASTSDVLQSKSTSEIPTKCNELSNLTSENSSSPSIIHQQDTDLCRHLEEPCFSLASALKELHKLLISCKGECKVLTSEVSQLEMVCKEQVQQKGFSEDERKGLDPDGQQQSSSSFNVRSEGGKKERSQPCNSGTENVSLESVTHMESASGEDAFEIPKFSGKSDLIVVTSAGKSDQQESSEQAKVLPEWFLSSTLEQSTVSSQPALDEGTSQDIQASLTRAPERSSSSAPDSPASLGGCEEPLPSPPAESTELSLVASPPAFSPADVDRILGAGFTTQEALEALEQADGNADLALLILLAKSIVVPT", "length": 1017, "header": "tr|A0A1D5NXK6-1|A0A1D5NXK6_CHICK Isoform 1 of DNA damage inducible 1 homolog 2 OS=Gallus gallus OX=9031 GN=DDI2 PE=1 SV=2 CANONICAL=A0A1D5NXK6-1" }, "locus": { "chromosome": "21", "start_pos": 6781302, "end_pos": 6762333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051312.1", "url": "https://www.ensembl.org/id/ENSGALT00010051312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030503.1", "url": "https://www.ensembl.org/id/ENSGALP00010030503.1" } ] } }, { "isoform_ac": "A0A8V0ZI87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI87/entry", "sequence": { "sequence": "MLLTVFCLRRDRSELTFSLQVDADFELQNFRALCELESGIPAAESQIVYAERPLTDNNRSLASYGLKDGDVVILRQKDTVEPRPSIRFPALPRIDFSSIAVPGTSAQQRQSPAQRLRPSPPDAPSFSQGLENPALLREMLLANPHELSLLKERNPPLAEALLSGDLDKFTRVLLEQQQDRARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLEIGTTGSQTAFLPEGELPECARLAYGAGREDVRPEEIADQELAEAIQKSVEEAERQKP", "length": 397, "header": "tr|A0A8V0ZI87-1|A0A8V0ZI87_CHICK Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Gallus gallus OX=9031 GN=DDI2 PE=1 SV=1 CANONICAL=A0A1D5NXK6-1" }, "locus": { "chromosome": "21", "start_pos": 6777976, "end_pos": 6762333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051319.1", "url": "https://www.ensembl.org/id/ENSGALT00010051319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030510.1", "url": "https://www.ensembl.org/id/ENSGALP00010030510.1" } ] } }, { "isoform_ac": "A0A8V0ZI89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI89/entry", "sequence": { "sequence": "MLLTVFCLRRDRSELTFSLQVDADFELQNFRALCELESGIPAAESQIVYAERPLTDNNRSLASYGLKDGDVVILRQKDTVEPRPSIRFPALPRIDFSSIAVPGTSAQQRQSPAQRLRPSPPDAPSFSQGLENPALLREMLLANPHELSLLKERNPPLAEALLSGDLDKFTRVLLEQQQDRARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLEIGTTGSQTAFLPEGELPECARLAYGAGREDVRPEEIADQELAEAIQKSVEEAENSDKETTSLEMPSLPASDGFQNPVQSSGLSSKICNPTNQLLDRSIFSPVSTRLSKASLTEPIDPKAVKSFESSTECQITPEKDYPLVLQHLSNISSLANNDHSLQTEEVNCCSPACLSQNTLEETFLADSLMECNTIEQGCGEEPLLEVTKENSLTDSTTKLGQIKNASLPSELKEPKQKNKLTIKHQMYKEPEKFEHLEEQTDKTDLEHPGNIGGVEKPAVEEEGRTVSQPESPPAEMREGRLEKADLSCVKGHIQASCSCVHMEVDTAERSVAEVHISASKQKWQAKNGRALDLNSDASSMELESLKSATSLSDAASTSDVLQSKSTSEIPTKCNELSNLTSENSSSPSIIHQQDTDLCRHLEEPCFSLASALKELHKLLISCKGECKVLTSEVSQLEMVCKEQVQQKGFSEDERKGLDPDGQQQSSSSFNVRSEGGKKERSQPCNSGTENVSLESVTHMESASGEDAFEIPKFSGKSDLIVVTSAGKSDQQESSEQAKVLPEWFLSSTLEQSTVSSQPALDEGTSQDIQASLTRAPERSSSSAPDSPASLGGCEEPLPSPPAESTELSLVASPPAFSPADVDRILGAGFTTQEALEALEQADGNADLALLILLAKSIVVPT", "length": 974, "header": "tr|A0A8V0ZI89-1|A0A1D5NXK6_CHICK Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Gallus gallus OX=9031 GN=DDI2 PE=1 SV=1 CANONICAL=A0A1D5NXK6-1" }, "locus": { "chromosome": "21", "start_pos": 6781302, "end_pos": 6762333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051315.1", "url": "https://www.ensembl.org/id/ENSGALT00010051315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030506.1", "url": "https://www.ensembl.org/id/ENSGALP00010030506.1" } ] } }, { "isoform_ac": "A0A8V0ZI94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI94/entry", "sequence": { "sequence": "MLLTVFCLRRDRSELTFSLQVDADFELQNFRALCELESGIPAAESQIVYAERPLTDNNRSLASYGLKDGDVVILRQKDTVEPRPSIRFPALPRIDFSSIAVPGTSAQQRQSPAQRLRPSPPDAPSFSQGLENPALLREMLLANPHELSLLKERNPPLAEALLSGDLDKFTRVLLEQQQDRARREQERIRLYSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLEIGTTGSQTAFLPEGELPECARLAYGAGREDVRPEEIADQELAEAIQKSVEEAGISSPMLCAGAIALRHSFDGFSNAEYNSLWTSSDLHDKKDRKTWICPCVSYKY", "length": 445, "header": "tr|A0A8V0ZI94-1|A0A8V0ZI94_CHICK Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Gallus gallus OX=9031 GN=DDI2 PE=1 SV=1 CANONICAL=A0A1D5NXK6-1" }, "locus": { "chromosome": "21", "start_pos": 6790241, "end_pos": 6762333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051324.1", "url": "https://www.ensembl.org/id/ENSGALT00010051324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030515.1", "url": "https://www.ensembl.org/id/ENSGALP00010030515.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425541", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" }, { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NXK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1017, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NXK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXK6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 846, "end_pos": 848 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NXA5-1", "uniprot_ac": "A0A1D5NXA5", "uniprot_id": "A0A1D5NXA5_CHICK", "mass": { "chemical_mass": 61149.0, "monoisotopic_mass": 61149.0 }, "refseq": { "ac": "XP_040504428", "name": "synaptic vesicle 2-related protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504428" }, "gene_names": [ { "name": "SVOP", "type": "recommended", "evidence": [ { "id": "A0A1D5NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5" } ] }, { "name": "SVOP", "type": "synonym", "evidence": [ { "id": "XP_040504428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504428" } ] } ], "protein_names": [ { "name": "Synaptic vesicle 2-related protein", "type": "recommended", "evidence": [ { "id": "A0A1D5NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5/entry#names_and_taxonomy" } ] }, { "name": "synaptic vesicle 2-related protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040504428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504428" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040504428.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504428" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXA5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SVOP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5", "locus": { "chromosome": "15", "start_pos": 6628127, "end_pos": 6649693, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022628", "url": "https://www.ensembl.org/id/ENSGALG00010022628" } ] } } ], "crossref": [ { "id": "A0A1D5NXA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034278", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17441", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17441", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416895", "url": "https://www.ncbi.nlm.nih.gov/gene/416895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416895", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416895", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLWFIWM", "url": "https://omabrowser.org/oma/group/LLWFIWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXA5", "url": "https://www.orthodb.org/?gene=A0A1D5NXA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRS8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXA5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDDLFQLRQLPVVKFRRTGESSRSEEDAISGEHEIQIEGVRTELEAIELEDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVITGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSGFAPIYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVLVMPTLGWRWLLILSALPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTEFFQAGDVCSISSRRKEVKAKCSLTCEYLTEEDYTDLLWTTLSEFPGVLVTLWIIDRIGRKKTMALSFFVFSFCSLLLFLCVGRNVLTVLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAAVASFFLPIETKGRGLQESSHREWGQEMVGRGSHSPGVTRSNSGSQE", "length": 548, "header": "tr|A0A1D5NXA5-1|A0A1D5NXA5_CHICK Isoform 1 of Synaptic vesicle 2-related protein OS=Gallus gallus OX=9031 GN=SVOP PE=3 SV=2 CANONICAL=A0A1D5NXA5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5/entry", "sequence": { "sequence": "MEDDLFQLRQLPVVKFRRTGESSRSEEDAISGEHEIQIEGVRTELEAIELEDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVITGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSGFAPIYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVLVMPTLGWRWLLILSALPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTEFFQAGDVCSISSRRKEVKAKCSLTCEYLTEEDYTDLLWTTLSEFPGVLVTLWIIDRIGRKKTMALSFFVFSFCSLLLFLCVGRNVLTVLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAAVASFFLPIETKGRGLQESSHREWGQEMVGRGSHSPGVTRSNSGSQE", "length": 548, "header": "tr|A0A1D5NXA5-1|A0A1D5NXA5_CHICK Isoform 1 of Synaptic vesicle 2-related protein OS=Gallus gallus OX=9031 GN=SVOP PE=3 SV=2 CANONICAL=A0A1D5NXA5-1" }, "locus": { "chromosome": "15", "start_pos": 6649485, "end_pos": 6632407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055053.1", "url": "https://www.ensembl.org/id/ENSGALT00010055053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033287.1", "url": "https://www.ensembl.org/id/ENSGALP00010033287.1" } ] } }, { "isoform_ac": "A0A8V0ZRS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS8/entry", "sequence": { "sequence": "MEDDLFQLRQLPVVKFRRTGESSRSEEDAISGEHEIQIEGVRTELEAIELEDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVITGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSGLKISVLWTLYYGILSGFAPIYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVLVMPTLGWRWLLILSALPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTEFFQAGDVCSISSRRKEVKAKCSLTCEYLTEEDYTDLLWTTLSEFPGVLVTLWIIDRIGRKKTMALSFFVFSFCSLLLFLCVGRNVLTVLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAAVASFFLPIETKGRGLQESSHREWGQEMVGRGSHSPGVTRSNSGSQE", "length": 524, "header": "tr|A0A8V0ZRS8-1|A0A1D5NXA5_CHICK Computationally mapped isoform of Synaptic vesicle 2-related protein OS=Gallus gallus OX=9031 GN=SVOP PE=3 SV=1 CANONICAL=A0A1D5NXA5-1" }, "locus": { "chromosome": "15", "start_pos": 6649485, "end_pos": 6632407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055048.1", "url": "https://www.ensembl.org/id/ENSGALT00010055048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033284.1", "url": "https://www.ensembl.org/id/ENSGALP00010033284.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416895", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AWK2-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "SVOP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPISDFLYQAAIMTRFALSSRVVKFRRTGESARSEDDTASGEHEVHIEGVRAGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVILAVFVMPSLGWRWLLLLSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAEIRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVVFSFCSLLLFICVGRNMLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGAHGTGVARSNSGSQE", "length": 551 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LZY3-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "Svop", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEDLFQLRQLPVVKFRRTGESARSEDDLASGEHDVQIEGVRVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGVLSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGWRWLLMLSAAPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDICSISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFVIFSLCSLLLFICIGRNMLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAAVASCFLPIETKGRGLQESSHREWGQEMVGRGTNSEGVPRSNSGSQE", "length": 548 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1JP63-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "SVOP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEDLFQLRQLPVVKFRRTGESARSEDDTASGEHEVQIEGVRAGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVVFSFCSLLLFICVGRNMLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGAHGTGVARSNSGSQE", "length": 548 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BFT9-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "Svop", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEDLFQLRQLPVVKFRRTGESARSEDDAASGEHDIQIEGVRVGLEAIELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGWRWLLLLSAAPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFIIFSLCSLLLFICIGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAGVASCFLPIETKGRALQESSHREWGQEMVGRGTNSAGVPRSDSGSQE", "length": 548 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4V2-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "SVOP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDLFQLRQLPVVKFRRTGESARSEDDTASGEHEVQIEGVHVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGMHGAGVTRSNSGSQE", "length": 548 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q940M4-1", "protein_name": "Organic cation/carnitine transporter 7", "gene_name": "OCT7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADGNTRFTVDEALVAMGFGKFQIYVLAYAGMGWVAEAMEMMLLSFVGPAVQSLWNLSARQESLITSVVFAGMLIGAYSWGIVSDKHGRRKGFIITAVVTFVAGFLSAFSPNYMWLIILRCLVGLGLGGGPVLASWYLEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPRLGWRWLLAFSSVPSSLLLLFYRWTSESPRYLILQGRKAEALAILEKIARMNKTQLPPGVLSSELETELEENKNIPTENTHLLKAGESGEAVAVSKIVLKADKEPGFSLLALLSPTLMKRTLLLWVVFFGNAFAYYGVVLLTTELNNSHNRCYPTEKQLRNSNDVNYRDVFIASFAEFPGLLISAAMVDRLGRKASMASMLFTCCIFLLPLLSHQSPFITTVLLFGGRICISAAFTVVYIYAPEIYPTAVRTTGVGVGSSVGRIGGILCPLVAVGLVHGCHQTIAVLLFEVVILVSGICVCLFPFETSGRDLTDSISASKEPPSASV", "length": 500 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z2I7-1", "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "Svop", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEDLFQLRQLPVVKFRRTGESARSEDDAASGEHDVQIEGVRVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGWRWLLLLSAAPLLVFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFVIFSLCSLLLFICIGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRALQESSHREWGQEMVGRGTNSTGVPRSNSGSQE", "length": 548 }, "evidence": [ { "id": "A0A1D5NXA5", "url": "https://omabrowser.org/oma/group/A0A1D5NXA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXA5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXA5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NXA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NXA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXA5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXA5" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 513, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P1W4-1", "uniprot_ac": "A0A1D5P1W4", "uniprot_id": "A0A1D5P1W4_CHICK", "mass": { "chemical_mass": 71635.0, "monoisotopic_mass": 71635.0 }, "refseq": { "ac": "XP_015147609", "name": "E3 SUMO-protein ligase PIAS1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147609" }, "gene_names": [ { "name": "PIAS1", "type": "recommended", "evidence": [ { "id": "A0A1D5P1W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ] }, { "name": "PIAS1", "type": "synonym", "evidence": [ { "id": "XP_015147609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147609" } ] } ], "protein_names": [ { "name": "E3 SUMO-protein ligase PIAS1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147609" } ] }, { "name": "Protein inhibitor of activated STAT 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P1W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147609" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIAS1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4", "locus": { "chromosome": "10", "start_pos": 19162093, "end_pos": 19110135, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017264", "url": "https://www.ensembl.org/id/ENSGALG00010017264" } ] } } ], "crossref": [ { "id": "A0A1D5P1W4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P1W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007970", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007970", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16818", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16818", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427514", "url": "https://www.ncbi.nlm.nih.gov/gene/427514", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PASPMNN", "url": "https://omabrowser.org/oma/group/PASPMNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1W4", "url": "https://www.orthodb.org/?gene=A0A1D5P1W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTH8", "url": "https://www.orthodb.org/?gene=A0A8V0YTH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZY2", "url": "https://www.orthodb.org/?gene=A0A8V0YZY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1P4", "url": "https://www.orthodb.org/?gene=A0A8V0Z1P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232118", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232118", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-877312", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877312", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSLSSVHPSSMPATLSPSTIPQLSYDGHPATSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTTSYNGVDGCISSSLEHQVSSHQQSNKNKKVEVIDLTIDSSSDEEEEEPSAKRSCPSISPASPINNKGILNLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSASDDQELLHSRFFPYTSSQMFLDQLNAGGSSSLPATNGSNSGSNSSLVSSNSLRENHGHPVASRSGADTASIFGIISDIISLD", "length": 651, "header": "tr|A0A1D5P1W4-1|A0A1D5P1W4_CHICK Isoform 1 of Protein inhibitor of activated STAT 1 OS=Gallus gallus OX=9031 GN=PIAS1 PE=3 SV=1 CANONICAL=A0A1D5P1W4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4/entry", "sequence": { "sequence": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSLSSVHPSSMPATLSPSTIPQLSYDGHPATSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTTSYNGVDGCISSSLEHQVSSHQQSNKNKKVEVIDLTIDSSSDEEEEEPSAKRSCPSISPASPINNKGILNLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSASDDQELLHSRFFPYTSSQMFLDQLNAGGSSSLPATNGSNSGSNSSLVSSNSLRENHGHPVASRSGADTASIFGIISDIISLD", "length": 651, "header": "tr|A0A1D5P1W4-1|A0A1D5P1W4_CHICK Isoform 1 of Protein inhibitor of activated STAT 1 OS=Gallus gallus OX=9031 GN=PIAS1 PE=3 SV=1 CANONICAL=A0A1D5P1W4-1" }, "locus": { "chromosome": "10", "start_pos": 19158410, "end_pos": 19110161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041626.1", "url": "https://www.ensembl.org/id/ENSGALT00010041626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024351.1", "url": "https://www.ensembl.org/id/ENSGALP00010024351.1" } ] } }, { "isoform_ac": "A0A8V0YTH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH8/entry", "sequence": { "sequence": "SADTQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSLSSVHPSSMPATLSPSTIPQLSYDGHPATSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTTSYNGVDGCISSSLEHQVSSHQQSNKNKKVEVIDLTIDSSSDEEEEEPSAKRSCPSISPASPINNKGILNLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQVS", "length": 551, "header": "tr|A0A8V0YTH8-1|A0A1D5P1W4_CHICK Computationally mapped isoform of Protein inhibitor of activated STAT 1 OS=Gallus gallus OX=9031 GN=PIAS1 PE=3 SV=1 CANONICAL=A0A1D5P1W4-1" }, "locus": { "chromosome": "10", "start_pos": 19156618, "end_pos": 19129294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041616.1", "url": "https://www.ensembl.org/id/ENSGALT00010041616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024347.1", "url": "https://www.ensembl.org/id/ENSGALP00010024347.1" } ] } }, { "isoform_ac": "A0A8V0YZY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY2/entry", "sequence": { "sequence": "MAFRHFAFMKFLANPEFCRNILSVRVTGCVMVNKPLTSTERSSEVECRLQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSLSSVHPSSMPATLSPSTIPQLSYDGHPATSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTTSYNGVDGCISSSLEHQVSSHQQSNKNKKVEVIDLTIDSSSDEEEEEPSAKRSCPSISPASPINNKGILNLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSASDDQELLHSRFFPYTSSQMFLDQLNAGGSSSLPATNGSNSGSNSSLVSSNSLRENHGHPVASRSGADTASIFGIISDIISLD", "length": 692, "header": "tr|A0A8V0YZY2-1|A0A1D5P1W4_CHICK Computationally mapped isoform of Protein inhibitor of activated STAT 1 OS=Gallus gallus OX=9031 GN=PIAS1 PE=3 SV=1 CANONICAL=A0A1D5P1W4-1" }, "locus": { "chromosome": "10", "start_pos": 19158410, "end_pos": 19128684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041620.1", "url": "https://www.ensembl.org/id/ENSGALT00010041620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024349.1", "url": "https://www.ensembl.org/id/ENSGALP00010024349.1" } ] } }, { "isoform_ac": "A0A8V0Z1P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P4/entry", "sequence": { "sequence": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSLSSVHPSSMPATLSPSTIPQLSYDGHPATSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTTSYNGVDGCISSSLEHQVSSHQQSNKNKKVEVIDLTIDSSSDEEEEEPSAKRSCPSISPASPINNKGILNLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQVS", "length": 555, "header": "tr|A0A8V0Z1P4-1|A0A1D5P1W4_CHICK Computationally mapped isoform of Protein inhibitor of activated STAT 1 OS=Gallus gallus OX=9031 GN=PIAS1 PE=3 SV=1 CANONICAL=A0A1D5P1W4-1" }, "locus": { "chromosome": "10", "start_pos": 19156618, "end_pos": 19110161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041625.1", "url": "https://www.ensembl.org/id/ENSGALT00010041625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024350.1", "url": "https://www.ensembl.org/id/ENSGALP00010024350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232118", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232118", "resource": "Reactome", "description": "SUMOylation of transcription factors" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-5696395", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "resource": "Reactome", "description": "Formation of Incision Complex in GG-NER" }, { "id": "R-GGA-877312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877312", "resource": "Reactome", "description": "Regulation of IFNG signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD", "length": 651 }, "evidence": [ { "id": "A0A1D5P1W4", "url": "https://omabrowser.org/oma/group/A0A1D5P1W4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88907-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "Pias1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD", "length": 651 }, "evidence": [ { "id": "A0A1D5P1W4", "url": "https://omabrowser.org/oma/group/A0A1D5P1W4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": 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"id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1W4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1W4" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell periphery", "id": 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This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040522590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040522590" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KPNA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5", "locus": { "chromosome": "3", "start_pos": 63456678, "end_pos": 63477067, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014707", "url": "https://www.ensembl.org/id/ENSGALG00010014707" } ] } } ], "crossref": [ { "id": "A0A8V0YPJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPJ5", "database": 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"Protein" ] }, { "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIMSSPGKDNFRMKSYKNNALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPGNEESMVESPIQDPDISSTVPIPEEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQAVWALGNIAGDNAECRDFVLNCGILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 539, "header": "tr|A0A8V0YPJ5-1|A0A8V0YPJ5_CHICK Isoform 1 of Importin subunit alpha OS=Gallus gallus OX=9031 GN=KPNA5 PE=3 SV=1 CANONICAL=A0A8V0YPJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH4/entry", "sequence": { "sequence": "MDRKLFKRRNVSLPGNEESMVESPIQDPDISSTVPIPEEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQAVWALGNIAGDNAECRDFVLNCGILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 497, "header": "tr|A0A8V0YPH4-1|A0A8V0YPH4_CHICK Computationally mapped isoform of Importin subunit alpha OS=Gallus gallus OX=9031 GN=KPNA5 PE=3 SV=1 CANONICAL=A0A8V0YPJ5-1" }, "locus": { "chromosome": "3", "start_pos": 63472239, "end_pos": 63460068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035321.1", "url": "https://www.ensembl.org/id/ENSGALT00010035321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020562.1", "url": "https://www.ensembl.org/id/ENSGALP00010020562.1" } ] } }, { "isoform_ac": "A0A8V0YPJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5/entry", "sequence": { "sequence": "MDIMSSPGKDNFRMKSYKNNALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPGNEESMVESPIQDPDISSTVPIPEEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQAVWALGNIAGDNAECRDFVLNCGILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 539, "header": "tr|A0A8V0YPJ5-1|A0A8V0YPJ5_CHICK Isoform 1 of Importin subunit alpha OS=Gallus gallus OX=9031 GN=KPNA5 PE=3 SV=1 CANONICAL=A0A8V0YPJ5-1" }, "locus": { "chromosome": "3", "start_pos": 63476611, "end_pos": 63460068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035340.1", "url": "https://www.ensembl.org/id/ENSGALT00010035340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020570.1", "url": "https://www.ensembl.org/id/ENSGALP00010020570.1" } ] } }, { "isoform_ac": "A0A8V0YRA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA8/entry", "sequence": { "sequence": "MSSPGKDNFRMKSYKNNALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPGNEESMVESPIQDPDISSTEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQVTECLPSPPVFFLLIQNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 492, "header": "tr|A0A8V0YRA8-1|A0A8V0YPJ5_CHICK Computationally mapped isoform of Importin subunit alpha OS=Gallus gallus OX=9031 GN=KPNA5 PE=3 SV=1 CANONICAL=A0A8V0YPJ5-1" }, "locus": { "chromosome": "3", "start_pos": 63474562, "end_pos": 63460068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035357.1", "url": "https://www.ensembl.org/id/ENSGALT00010035357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020576.1", "url": "https://www.ensembl.org/id/ENSGALP00010020576.1" } ] } }, { "isoform_ac": "A0A8V0YRB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB3/entry", "sequence": { "sequence": "MPHTDMAAQRSSRKPRPLHGAVEATPAPRRRAGPAGSGEARPWVVRRAAAAILRSGWGLSAAFRAKRSAVGFSRLGGGGRGASPLRWLFKRRNVSLPGNEESMVESPIQDPDISSTVPIPEEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQAVWALGNIAGDNAECRDFVLNCGILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 580, "header": "tr|A0A8V0YRB3-1|A0A8V0YPJ5_CHICK Computationally mapped isoform of Importin subunit alpha OS=Gallus gallus OX=9031 GN=KPNA5 PE=3 SV=1 CANONICAL=A0A8V0YPJ5-1" }, "locus": { "chromosome": "3", "start_pos": 63476868, "end_pos": 63460068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035365.1", "url": "https://www.ensembl.org/id/ENSGALT00010035365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020581.1", "url": "https://www.ensembl.org/id/ENSGALP00010020581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1N1K5-1", "protein_name": "Importin subunit alpha", "gene_name": "KPNA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDESMLENPIQDPDISSTVPIPEEEVITSDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGSNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFQL", "length": 539 }, "evidence": [ { "id": "A0A8V0YPJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RTU5-1", "protein_name": "Importin subunit alpha", "gene_name": "KPNA5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPKSDESMLESPIQDPDITSTVPIPEEEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSDRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGNDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGVNPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFHL", "length": 539 }, "evidence": [ { "id": "A0A8V0YPJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15131-1", "protein_name": "Importin subunit alpha-6", "gene_name": "KPNA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQFIFQQQEAPMDGFQL", "length": 539 }, "evidence": [ { "id": "A0A8V0YPJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q503E9-1", "protein_name": "Importin subunit alpha-6", "gene_name": "kpna5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPPGDESMLECPIQDPDVSSTVPVSGEGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLRRSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNIAGDNAECRDYVLNCGILPSLQQLLAKSNRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIKKEACWTVSNITAGNRAQIQAVIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLNTIKPMCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEEDASIVPQVDQNQGQYIFQQSEGPMEGFQL", "length": 539 }, "evidence": [ { "id": "A0A8V0YPJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q56R16-1", "protein_name": "Importin subunit alpha-6", "gene_name": "Kpna5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDDCMLESPIQDPDVSSTVPIPEEDMITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLIEVLQKAEFRTRKEAAWAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVEEDDPSLVPQVDEQQRQFLFQQCEAPGEGFQL", "length": 539 }, "evidence": [ { "id": "A0A8V0YPJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" }, { "name": "NLS-dependent protein nuclear import complex", "id": "GO:0042564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ5" }, { "id": "PS51214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IBB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 60, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNI2-1", "uniprot_ac": "A0A8V0YNI2", "uniprot_id": "A0A8V0YNI2_CHICK", "mass": { "chemical_mass": 218488.0, "monoisotopic_mass": 218488.0 }, "refseq": {}, "gene_names": [ { "name": "KIF26A", "type": "recommended", "evidence": [ { "id": "A0A8V0YNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ] } ], "protein_names": [ { "name": "Kinesin family member 26A", "type": "synonym", "evidence": [ { "id": "A0A8V0YNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIF26A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2", "locus": { "chromosome": "5", "start_pos": 50313238, "end_pos": 50212400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016247", "url": "https://www.ensembl.org/id/ENSGALG00010016247" } ] } } ], "crossref": [ { "id": "cd00106", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00106", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423489", "url": "https://www.ncbi.nlm.nih.gov/gene/423489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057090", "database": 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWY6", "url": "https://www.orthodb.org/?gene=A0A8V0YWY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YWZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1P9", "url": "https://www.orthodb.org/?gene=A0A8V0Z1P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1Q9", "url": "https://www.orthodb.org/?gene=A0A8V0Z1Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21608:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21608:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23081", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23081", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVTGRRGPGLEARAEGVAEGSAGRELSPRKKPPSAASSAAPEEERCARRPPPEGAGSAAVGSEARPLERAAAGGWCRSCQAQLAELRRQAARLAAGGCPPNAPPDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 2044, "header": "tr|A0A8V0YNI2-1|A0A8V0YNI2_CHICK Isoform 1 of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2/entry", "sequence": { "sequence": "MSAVTGRRGPGLEARAEGVAEGSAGRELSPRKKPPSAASSAAPEEERCARRPPPEGAGSAAVGSEARPLERAAAGGWCRSCQAQLAELRRQAARLAAGGCPPNAPPDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 2044, "header": "tr|A0A8V0YNI2-1|A0A8V0YNI2_CHICK Isoform 1 of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50215281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039069.1", "url": "https://www.ensembl.org/id/ENSGALT00010039069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022566.1", "url": "https://www.ensembl.org/id/ENSGALP00010022566.1" } ] } }, { "isoform_ac": "A0A8V0YUW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW7/entry", "sequence": { "sequence": "MRWPFIEIGRCLFFWHKDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1955, "header": "tr|A0A8V0YUW7-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50243219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039041.1", "url": "https://www.ensembl.org/id/ENSGALT00010039041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022548.1", "url": "https://www.ensembl.org/id/ENSGALP00010022548.1" } ] } }, { "isoform_ac": "A0A8V0YUZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ2/entry", "sequence": { "sequence": "MAFPKPPDASTAPRRSPGLLEIGALCLDSDIIFGFTSHLLRRKAKVAEGSAGRELSPRKKPPSAASSAAPEEERCARRPPPEGAGSAAVGSEARPLERAAAGGWCRSCQAQLAELRRQAARLAAGGCPPNAPPDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 2071, "header": "tr|A0A8V0YUZ2-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50213678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039084.1", "url": "https://www.ensembl.org/id/ENSGALT00010039084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022573.1", "url": "https://www.ensembl.org/id/ENSGALP00010022573.1" } ] } }, { "isoform_ac": "A0A8V0YVA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA8/entry", "sequence": { "sequence": "MFPLWWVLLRFSALYWNSEDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1957, "header": "tr|A0A8V0YVA8-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50239016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039050.1", "url": "https://www.ensembl.org/id/ENSGALT00010039050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022555.1", "url": "https://www.ensembl.org/id/ENSGALP00010022555.1" } ] } }, { "isoform_ac": "A0A8V0YWY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY2/entry", "sequence": { "sequence": "MVVLGRIFRDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEV", "length": 1906, "header": "tr|A0A8V0YWY2-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50231687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039056.1", "url": "https://www.ensembl.org/id/ENSGALT00010039056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022559.1", "url": "https://www.ensembl.org/id/ENSGALP00010022559.1" } ] } }, { "isoform_ac": "A0A8V0YWY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY6/entry", "sequence": { "sequence": "MMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEPFQDVEKGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1900, "header": "tr|A0A8V0YWY6-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50246246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039065.1", "url": "https://www.ensembl.org/id/ENSGALT00010039065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022564.1", "url": "https://www.ensembl.org/id/ENSGALP00010022564.1" } ] } }, { "isoform_ac": "A0A8V0YWZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ1/entry", "sequence": { "sequence": "MAFPKPPDASTAPRRSPGLLEIGALCLDSDIIFGFTSHLLRRKAKDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1983, "header": "tr|A0A8V0YWZ1-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50213678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039075.1", "url": "https://www.ensembl.org/id/ENSGALT00010039075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022569.1", "url": "https://www.ensembl.org/id/ENSGALP00010022569.1" } ] } }, { "isoform_ac": "A0A8V0Z1P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P9/entry", "sequence": { "sequence": "MGGYYFSDFLSENPDAFLHPLLLLSLGVRSQWLQDPRLSALIFDKLQVPDYLQRNRNEGESRCETCATHLNQLKQEAIQMMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTKVGHFRGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1972, "header": "tr|A0A8V0Z1P9-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50241572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039047.1", "url": "https://www.ensembl.org/id/ENSGALT00010039047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022552.1", "url": "https://www.ensembl.org/id/ENSGALP00010022552.1" } ] } }, { "isoform_ac": "A0A8V0Z1Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q9/entry", "sequence": { "sequence": "MMHTLNQASYSEMPDLPPGATAVTSMVPRVVTVSSQRDLPLITGQVGRQPGKSPNLFSGTEKKKGLGWSQGTGSFPNSSVQVTVAPSGLSGALSSVTIQAQQYLEGMWSISRVNSFLPQACLAETAPESVWDGPSVQVSSGQNNSDPTGPSGSAASQSLVAPAGVSAGASAAASFFIRAAQKLNLSSKRKKYHPPLPHTHDFSIYATNFSGILQLCPPPAPPCLLRAVSKIKDNPGIGKVKVMVRICPSQGAHETSESMSFLKVDPRKKQITLYDPAASGPSNGGHRRGVVAVPKMFAFDAVFPQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKLGKSFTMIGKDSSTQSLGIIPCAISWLFKLINERKEKTGTRFSIRVSAVEISGKDENLKDLLAEVATGSLQDGQSPGVYLREDPICGTQLQNQSELRAPTAEKAAFFLDAAIAARSTSKPECEEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLSKSRDGGGSLCLSLSALGNVILALINGAKHVPYKDNKLTMLLRESLGNINCRTTMIAHISDSPANYAETLTTIQLSSRIHRMRKKKSKYASSSSGGESSCEEGHVRRPPHLRPFHPRTVALDPDLPVLSISSDPDYSSSSEQSCDTVIYVGPNGAALSDRELTDNEGPPEFVPIIPSLNKKRSKDNSASGRSSDKDHFKCNTFAELQERLECIDGSEEPIRYACGETSVTSNCSPVPGGTESTQSKLIKEKLSSPSGGFKKPVSQETASPKKGHNIPFQAVAPRGGNGNCHEKSTPHLKSELSVPQSSTDSKVLDGERETITNSLQLSRCSPSKNPEQNKATAECVIKEKSFYVKRPLPSPAPPPPQQKEQVPSSKAQSLELDNSNAVRTPPVGMSKQMANKPEQNSVGSTFLVGSNGQSQSGAIEVHSFRSAFRGKCFDRDILTTTVTLQQPVELNGEDELVFTVVEELSISGIMDNGRPSSIISFNSDCSLQALASGSRPVSIISSINDEFDAYTSQETSTGVNIDIVVPFAKDPFTSSRRSSISSWLSEVSICTIESDGAQSSDSFVAQTSYSCSKSEDPFNLDSPNLSVPLKSALNDSGFCFSELDSESMSSSKLSSGFGKSPQTSETTKASQIKSAFCVSDQPVKIKCNSRDTPVIETIHSSLPRKTKTTSSPIHNNTVISYKDLQNPHGVFEDPWLLRTDNQLETKPTDALLSPKSHAFGTDKQPGKAAQYFGISSGPMKSQTMLACSQRVVDGCEMACKSSSGAAKKSEAVMKMPQLKRGATTLGVMPVSHANNSTLSEAITRGNSDTPMATGSLKSSLGKKSMPQKSSMLPRPGGPMPPTPPVRKSSLEQKPVALGNGGGKASSLEFARASTPKAEDELDLRLKAGSYFSESASSRMNLKGDHSLPKMTSSLKAKASKSEAVHRYGSHMSLERCDSLTSVGSKANLVRENGSTGNVRAGRSVPRLGVPPVASGGALPLSFNNPAPGKNSQAKPTANQKVQASGNKNRGLSASGSKSLSSSVKSLAQPVGKSSGMAPGGKAAPRSMQPVGGKPGRGTIMGTKQAMRAANSRVNELVSGGSTDSDSGNDSGINLSDEKSPIPVLPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSPGRMRSLKSPKKRSTGLQRRRLIPAPLPDAASLGRKPSVTGQWVDLPPLPGTLKEPFEIKVYEIDDVERLHRHRQEETEGLMYFHTKLKILERRQQRIREVKAKHEFLKEELEETKCRLMMDPNKWKEDFEVDPDLDKESQEYLEALEQVTEELEQCVNLCKSHIMIVTCFDIGITDAQDGVREVEV", "length": 1884, "header": "tr|A0A8V0Z1Q9-1|A0A8V0YNI2_CHICK Computationally mapped isoform of Kinesin family member 26A OS=Gallus gallus OX=9031 GN=KIF26A PE=3 SV=1 CANONICAL=A0A8V0YNI2-1" }, "locus": { "chromosome": "5", "start_pos": 50311944, "end_pos": 50246246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039061.1", "url": "https://www.ensembl.org/id/ENSGALT00010039061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022562.1", "url": "https://www.ensembl.org/id/ENSGALP00010022562.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1508, "start_aa": "Thr", "end_pos": 1508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1508", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423489", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480QJM0-1", "protein_name": "Kinesin family member 26A", "gene_name": "KIF26A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGRGAPLCAAQPVVAEGGPAREPLQLLEVSPRKRLTAGPEQDPCGSRPAPEGAGAGAEQGHSAGGGGWCRHCHTKLAELKRQAWKLVSGPGTPLRDPCLSALLLDKLPACRPEAERRCDVCATRLNQLSPEALRLLQAPASREDPDAPRGGPGLTPPSTGTGAATSQRDVPAPAGRQPSRAGPDRRKGLAWPSGPSVQVSVAPAGLGGALSTVTIQAQQCLEGMWSVSRVNSFLPPSCLAEAAVAAVAVADTVRDGPPSVGPDGMLKTWAPGGACSAALVTPAPGTPVGGSTGPSAAASFFLRAAQKLSLASKRKKPHPPPAPTARGASTYPTDFSGVLQLWPPPAPPCLLRAASKAKDNPSSVGKVKVMLRIWPEQGAQRSAESTSFLKVDPRKKQVTLYDPAAGPPGSAGSRRATPAAVPKMFAFDAVFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHTSLGKSFTMIGRDSSPQSLGVVPCAISWLFRLLDERKERTGTRFSVRVSAVEVCGRDQSLRDLLAEVASSSLQDAQSPGVYLREDPVCGAQLQNQSELRAPTAERAAFYLDAALAARSSGRAGCSEDARCSSHVLFTLHVYQYRMEKCSRGGMSGGRSRLHLFDLGSCEGAPGRGGEAPGGPLCLSLSALGSIVLALVSGAKHVPHREHRLTTLLRESLAAASCRATMIAHVSDAPARHAETLSTVQLAARIHRLRRKKVKYASSSSGGDSSCEEGRAHRPPHLRHFHPRSVAPDPDRRAPSSPGDPDYSSSSEQSCDTVIYVGPGGAALSDRELTDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGPDGAQASPARGSRKPSLPEAVAPRKATGSPLAASTPRASPVPDTRRGAAEPSKADGDQGEGGSSRPELPVPDKPTVGGGRRPLPSPAPPPPRQPDAGGAPEEPGGADGVVRTPPLGTSGQAGCPRQPARGHRLERGLLTTTVTLQQPVELNGEDELVFTLVEELSLGALGGPGRPASLASFGSDCSLQALASGSRPVSIISSINDEFDAYTSKPPGGAPDGAAWTGSSHSSSISSWLSEVSVCTADGLGPTPQPPSRASPDPFSPDAPAGPDPLGPLIPDSSVEDSSLQFSEQDRVDSPGPAWSPRPGEEGAAAATRPGWEPRAASPGRAAPAQTLHSSLPRKPRSSSTASRVGCTRLAPAPPGPGGPFEDPWLLRADECGPIHLASASRAPSPALMPARRVVDGCEVGRVAQRPEAMAQIPPLRRGATTLGVTTPSASFRDAPTEAAACLGSPKPAPGSRKSVAAKGGLCPRPGGAAPPAPPERKSSLEHRSSPAPALPQAGSLVWAGAAAFLRAEGEARPGSRADHSIPRATSSLKARAGKAEAASRPTTHGSLERCEGLAQGGSKAREAPGRPARTVPRLGVPPASPTPGPAPACRSSPAKGVGAPKPPTSGGKGRSLAAAGSRALGAAVKPLSPAAGRTPGGPGTGPRVVPRVAPGVGAKASRGTIMGAKQALRAAHSRVNELAAGGAHSRSGLSWGSADSDSGNDSGVNVSEERPPVGPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMMRDSEATGSASSAPDSLSDSGAASPGARSRSLKSPKRRATGLQRRRLIPAPLPDAAALSRKPSLPGQWVDLPPPLSGSLKEPFEIKVYEIDDVERLQRHRPAPREDPAEPFQNAEKGLVCVGAKLRLAERRQQRLREVQAKRQVLCEELAETQGRLMLEPGRWLEQFEVDPELEPESAAYLAALERATAALEQRVNLCKARVMMVTCFDISAAAPAAAPGPQEVDV", "length": 1855 }, "evidence": [ { "id": "A0A8V0YNI2", "url": "https://omabrowser.org/oma/group/A0A8V0YNI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZUT0-1", "protein_name": "Kinesin family member 26A", "gene_name": "Kif26a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPGSPEPPRGAPRKVPSLLEMGSLCLDSDIILGFTSHLLRRRGKVAECRSARESPPLEVSPRKRLPAGLDQDLCSSRPAPEGAGASAEQGHSTGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPSCRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPDASRGGLGAPSPRDPPGPVGLMGRQPPVGPDRRKAAAWPSGPSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCPPTAGSDRMSKAWGRGTACTTALVTPAPGTSAGGSTAPSAAASFFIRAAQKLSLASKRKKHPPPPAPSARGSSTYATDFSGTLQLWPPPVPPCLLRAASKAKENPSNFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDPAAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVGGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGCLQDTQSPGVYLREDPVCGTQLRNQNELRAPTAEKAAFYLDAALAARSTSRAGCGEDARRTSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCEAAPSRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHTLTMLLRESLATTSCCTTMIAHISDSPTHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRTVVLDPDRSAPALSGDPDYSSSSEQSCDTVIYVGPGGTALSDRELTDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEGFPGPQGGSDGAQASPSRGSRKPSLPESTCLRKAVAPSVVTGCPRSSSGQETPRSTSEPSKTGPQGDQRVDGTRPEPPAPDKITGGGGRRLLPSPAPPPPRQPEARGVPTEPGGEGADSGPRTPPVGMSGQAPLPALLSDSAYPSARGRHLDRGLLTTTVTLQQPVELNGEDELVFTLVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQVSEGPGDAGELPEGTVWPGGSPASSIGSWLSDVGVCLPESRGTTPQPPFNPDSAAGPGPPEFLTPGSSLEDSKVRSSECGRPDNPGSSARSPHPGEAVSITQTQPGREPWARSPHEAASAQTIHSSLPRKPRTTSTVSRARPSRGPYSPGGLFEDPWLLRAEDCDTRHIASTGRAPSPTPGSPRLPETQIVLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPTASCGDAPAEATAHSGSLKATSSSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQALGLTRTGATSAFRGEEEARPTGRSDSSVPKATSSLKARAGKMEVPHRPSGHMSLERCEGLTHGSSKVRDVAGRPPRAVPRLGVPPASPPLGPGPACRSSPAKGIGATKPPAGGAKSRNLGPSTSRALGAPVKPLAPVVGKTTGGAVPGPRTAPRSVPGIGAKAGRGTIMGTKQAFRAAHSRVHELAASGSPGRGGLTWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGAASPGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDVEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATAAVPGPQEVDV", "length": 1912 }, "evidence": [ { "id": "A0A8V0YNI2", "url": "https://omabrowser.org/oma/group/A0A8V0YNI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q52KG5-1", "protein_name": "Kinesin-like protein KIF26A", "gene_name": "Kif26a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGRGASLCAVQPAVAECGPARETPPLEVSPRKRLPAGLDQDPCSSRPAPEGAGASAEQSHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPACRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPNASRGGLAAPSSRDPPGPVGLMGRQPPVGPDRRKATAWPPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCAPAAGPERMSKAWGRGAACTTALVTPAPGTSAGGSTGPSAAASFFIRAAQKLSLASKRKKHHPPPAPSTRGTSTYPTDFSGSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDPAAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNELRAPTAEKAAFYLDAALAARSTSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATTNCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRAVVLDPDRSAPGLSGDPDYSSSSEQSCDTVIYVGPGGMALSDRELTDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEAFPGPQGGSDGAQASPARGGRKPSLPEATPSRKAVAPTVVTSCPRGSPGHDTHRSASDPSKTGTQSEQRVDGSRPEPPASDKTSGGGGRRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTPPVGMSGQAALPPLLSDSAYLSPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQMSEGPGDPGEFPEGTAWAGGSPASSIGSWLSDVGVCLSESRGPTPQPPFSPNSAAGPGPPEFPTPGSSLEESKVRSSECGRPDNPGSARSLHPGEAVATTQTQPGREPWARSPHEVASAQTIHSSLPRKPRTTSTASRARPSRGPYSPGGLFEDPWLLRAEDCDTRQIASTGRAPSPTPGSPRLPETQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAASCGDAPAEAVVHSGSLKTTSGSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQALGLTRAGAPSAFRGEEEARPSGRSDSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEGLAHGSSKVRDVVGRPPRAVPRLGVPSASPPLGPAPACRNSPAKGVGATKPPAGGAKGRNLGPSTSRALGAPVKPLGPVAGKTAGGAVPGPRAAPRAVPGIGAKAGRGTIMGTKQAFRAAHSRVHELAASGSPSRGGLSWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGTASLGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDAEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATTAVPGPQEVDV", "length": 1881 }, "evidence": [ { "id": "A0A8V0YNI2", "url": "https://omabrowser.org/oma/group/A0A8V0YNI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULI4-1", "protein_name": "Kinesin-like protein KIF26A", "gene_name": "KIF26A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGRGVPLCAAQPAVAEGGPAREPPPLLEVSPRKRLPAGPDQDPCGSRPAPEGAGAGPEQGHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTTLRDPCLSALLLDKLPAPGALPACRPEAERRCDVCATHLQQLTREAMHLLQAPASHEDLDAPHGGPSLAPPSTTTSSRDTPGPAGPAGRQPGRAGPDRTKGLAWSPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGMWSVSRVNSFLPPACLAEAAVAAVAVADTVRECPPVAGPDGLSKAWGRGGVCTSALVTPTPGSVGGSTGPSAAASFFIRAMQKLSLASKRKKPHPPPPPATRGTSTYPTDFSGVLQLWPPPAPPCLLRAASKTKDNPGSIGKVKVMLRIWPAQGAQRSAEAMSFLKVDPRKKQVILYDPAAGPPGSAGPRRAATAAVPKMFAFDAVFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIEERRERTGTRFSVRVSAVEVCGRDQSLRDLLAEVAPGSLQDTQSPGVYLREDPVCGAQLQNQSELRAPTAEKAAFYLDAALAARSTSRAGCGEDARRSSHMLFTLHVYQYRMEKCGRGGMSGGRSRLHLIDLGSCEAAAGRAGEAAGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATAGCRTTMIAHVSDAPAQHAETLSTVQLAARIHRLRRKKAKYASSSSGGESSCEEGRARRPPHLRPFHPRTVALDPDRTPPCLPGDPDYSSSSEQSCDTVIYVGPGGAALSDRELTDNEGPPDFVPIIPALSRHRPSKGPRDADHFRCSTFAELQERLECMDGNEGPSGGPGGTDGAQASPARGGRKPSPPEAASPRKAVGTPMAASTPRGSSGPDTHQGTPEPCKAIVWGDQREDSSAWPELLVPEKAAVSGGRRPLPSPAPPPPQLLEACRAPEEPGGGGTDGVARTPPVGMSGQVAGSPMLPGATCPRLAAGSRCPERGLLTTTVTLQRPVELNGEDELVFTVVEELSLGALAGAGRPTSLASFDSDCSLRALASGSRPVSIISSINDEFDAYTSQAPEGGPLEGAAWAGSSHGSSISSWLSEVSVCTADSRDPTPQPRFSPDSLAGLDPGGPPALDGSLGDGSSGFLGPDRPDSPGPTWGPCPGEVAAVAPSRPGREPQAGPSRWASAAQTIHSSLPRKPRTASATTRVGCARLGQSPPGRGGLFEDPWLLRVGECDTQAASAGRAPSPTLGSPRLPEAQVMLACAQRVVDGCEVAARAARRPEAVARIPPLRRGATTLGVTTPAVSWGDAPTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGAAPPAPPTRKSSLEQRSSPASAPPHAVNPARVGAAAVLRGEEEPRPSSRADHSVPRATSSLKARASKVEAAHRLAGHASLERYEGLAHSSSKGREAPGRPPRAVPKLGVPPSSPTHGPAPACRSGAAKAVGAPKPPVGGGKGRGLVAGGSRALGPSVKLSTASVTGRSPGGPVAGPRAAPRAGPSVGAKAGRGTVMGTKQALRAAHSRVHELSASGAPGRGGSSWGSADSDSGHDSGVNVGEERPPTGPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFHHSGGSSGYESLRRDSEATGSASSAPDSMSESGAASPGARTRSLKSPKKRATGLQRRRLIPAPLPDTTALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRPRPTPREAPTQGLACVSTRLRLAERRQQRLREVQAKHKHLCEELAETQGRLMLEPGRWLEQFEVDPELEPESAEYLAALERATAALEQCVNLCKAHVMMVTCFDISVAASAAIPGPQEVDV", "length": 1882 }, "evidence": [ { "id": "A0A8V0YNI2", "url": "https://omabrowser.org/oma/group/A0A8V0YNI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "regulation of cell growth by extracellular stimulus", "id": "GO:0001560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "regulation of neuron migration", "id": "GO:2001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1250, "end_pos": 1252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1341, "end_pos": 1343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1460, "end_pos": 1462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1461, "end_pos": 1463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1618, "end_pos": 1620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1763, "end_pos": 1765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1768, "end_pos": 1770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1803, "end_pos": 1805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI2" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 390, "end_pos": 742, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1508 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1250, "end_pos": 1252 }, { "start_pos": 1260, "end_pos": 1262 }, { "start_pos": 1341, "end_pos": 1343 }, { "start_pos": 1460, "end_pos": 1462 }, { "start_pos": 1461, "end_pos": 1463 }, { "start_pos": 1618, "end_pos": 1620 }, { "start_pos": 1763, "end_pos": 1765 }, { "start_pos": 1768, "end_pos": 1770 }, { "start_pos": 1803, "end_pos": 1805 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 892, "end_pos": 894 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NTP6-1", "uniprot_ac": "A0A1D5NTP6", "uniprot_id": "A0A1D5NTP6_CHICK", "mass": { "chemical_mass": 137202.0, "monoisotopic_mass": 137202.0 }, "refseq": { "ac": "XP_040527821", "name": "protocadherin-11 X-linked isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821" }, "gene_names": [ { "name": "PCDH11X", "type": "recommended", "evidence": [ { "id": "A0A1D5NTP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ] }, { "name": "PCDH11X", "type": "synonym", "evidence": [ { "id": "XP_040527821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821" } ] } ], "protein_names": [ { "name": "Protocadherin 11 X-linked", "type": "synonym", "evidence": [ { "id": "A0A1D5NTP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6/entry#names_and_taxonomy" } ] }, { "name": "protocadherin-11 X-linked isoform X4", "type": "synonym", "evidence": [ { "id": "XP_040527821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040527821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NT53", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT53#function" }, { "database": "UniProtKB", "id": "ARBA00037723", "url": "https://www.uniprot.org/uniprotkb/ARBA00037723#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I8#function" }, { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6#function" }, { "database": "UniProtKB", "id": "E1BVK1", "url": "https://www.uniprot.org/uniprotkb/E1BVK1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCDH11X", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6", "locus": {} } ], "crossref": [ { "id": "A0A1D5NTP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NTP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006851", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006851", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422264", "url": "https://www.ncbi.nlm.nih.gov/gene/422264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NT53", "url": "https://www.orthodb.org/?gene=A0A1D5NT53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NTP6", "url": "https://www.orthodb.org/?gene=A0A1D5NTP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVK1", "url": "https://www.orthodb.org/?gene=E1BVK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040527821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527821", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NT53", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NT53-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVK1", "url": "https://www.uniprot.org/uniprotkb/E1BVK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BVK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLSGTYLLAVLLACIVFQSGAQEKNYTVREELPENVLIGNLLKDLNLTLDPDVPLSSPLQFKLVYKTGDVPLVRVEENTGEIFTTANRIDREKLCSGIFSENRCFYEVEVAVLPDEVFRLVKIRFLIEDINDNAPLFPSTVINISIPENTAINSRYSVPSAIDPDIGVNGIQHYELLKPKTAPKRTFGSITNDQGQNVFGLDIIETPEGDKWPQLIVQQILDREQKDTYVMKIKVEDGGSPPRSSTAILQVTVTDVNDNRPVFKENDIEVSIPENAPVGTSVSQLHATDADLGSNAQIHFYFSNQISSLAKKLFAIDNATGLITIREPLDREESPVHKLTVLASDGSSTPSRATVTVNVTDINDNVPSIDTRYIINPVNGTVLLSEKAPLNTKIALITVMDKDSDLNGKVTCFTDHDVPFRLKPVFDNQFLLETATFLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTQPIIGLSIPENNAPGTQLTKISATDADSGRNAEISYILGSDAPPIFNLDRRTGILTAVRKLDREKQDRYSFTVLAKDNGMPPLQTNATVTVSVLDQNDNSPAFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAAVTLSILNGRDNFIIDPLTGVIRPNITFDREQQGSYTFQVKAVDGGRLQRSSTAKVTINVVDVNDNRPVFVIPSSNYSYELVPTSSSPGSVVTKVFAVDNDTGMNAELRYSIIGGNSRGLFAIDQLTGNITLKEKVITSDHGLHRLVIKVNDLGQPESLYTIALVHLFVNETVTNSSYIQELVRRNMETPVGQNIGDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKNKQSGEWVSPNQENRQIKKKKKKKKRSPKSLLLNFVTIEESKPDDPGHEHINGTLDIPVELEEQTMGKYNWATTPTTFKPDSPDLAKHYKSASPQPTFQIKPETPVPPKKHHVIQELPLDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGGFKTPGPIHTRQHTKEMGRPQTPLKESTLEPWTQPQPQRRVTFHLPDGSQESCSDSGLGDHEPSSGASTSHPLPLGFPQEEYYEQASPNSRTEGDGNSDPESTIEVNLQKALAEASETCTQECLILGHSDNCWMPPSLTQYQQSNTPLPSFGFQQSWGRGARSDGRHTLGRPLPKDDTDKGQGGPRPQFYNTCERHCTSEDPVKVIPLANFAMSHQAAVSGSSTTFIHEHQL", "length": 1245, "header": "tr|A0A1D5NTP6-1|A0A1D5NTP6_CHICK Isoform 1 of Protocadherin 11 X-linked OS=Gallus gallus OX=9031 GN=PCDH11X PE=4 SV=2 CANONICAL=A0A1D5NTP6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NT53-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT53/entry", "sequence": { "sequence": "MDLLSGTYLLAVLLACIVFQSGAQEKNYTVREELPENVLIGNLLKDLNLTLDPDVPLSSPLQFKLVYKTGDVPLVRVEENTGEIFTTANRIDREKLCSGIFSENRCFYEVEVAVLPDEVFRLVKIRFLIEDINDNAPLFPSTVINISIPENTAINSRYSVPSAIDPDIGVNGIQHYELLKPKTAPKRTFGSITNDQGQNVFGLDIIETPEGDKWPQLIVQQILDREQKDTYVMKIKVEDGGSPPRSSTAILQVTVTDVNDNRPVFKENDIEVSIPENAPVGTSVSQLHATDADLGSNAQIHFYFSNQISSLAKKLFAIDNATGLITIREPLDREESPVHKLTVLASDGSSTPSRATVTVNVTDINDNVPSIDTRYIINPVNGTVLLSEKAPLNTKIALITVMDKDSDLNGKVTCFTDHDVPFRLKPVFDNQFLLETATFLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTQPIIGLSIPENNAPGTQLTKISATDADSGRNAEISYILGSDAPPIFNLDRRTGILTAVRKLDREKQDRYSFTVLAKDNGMPPLQTNATVTVSVLDQNDNSPAFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAAVTLSILNGRDNFIIDPLTGVIRPNITFDREQQGSYTFQVKAVDGGRLQRSSTAKVTINVVDVNDNRPVFVIPSSNYSYELVPTSSSPGSVVTKVFAVDNDTGMNAELRYSIIGGNSRGLFAIDQLTGNITLKEKVITSDHGLHRLVIKVNDLGQPESLYTIALVHLFVNETVTNSSYIQELVRRNMETPVGQNIGDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKNKQSGEWVSPNQENRQIKKKKKKKKRSPKSLLLNFVTIEESKPDDPGHEHINGTLDIPVELEEQTMGKYNWATTPTTFKPDSPDLAKHYKSASPQPTFQIKPETPVPPKKHHVIQELPLDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGGFKTPGPIHTRQGLQYTSSEPKSFFHCLLKSTL", "length": 1046, "header": "tr|A0A1D5NT53-1|A0A1D5NT53_CHICK Computationally mapped isoform of Protocadherin 11 X-linked OS=Gallus gallus OX=9031 GN=PCDH11X PE=4 SV=2 CANONICAL=A0A1D5NTP6-1" }, "locus": { "chromosome": "4", "start_pos": 6923596, "end_pos": 6904480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043731.1", "url": "https://www.ensembl.org/id/ENSGALT00010043731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026018.1", "url": "https://www.ensembl.org/id/ENSGALP00010026018.1" } ] } }, { "isoform_ac": "A0A1D5NTP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6/entry", "sequence": { "sequence": "MDLLSGTYLLAVLLACIVFQSGAQEKNYTVREELPENVLIGNLLKDLNLTLDPDVPLSSPLQFKLVYKTGDVPLVRVEENTGEIFTTANRIDREKLCSGIFSENRCFYEVEVAVLPDEVFRLVKIRFLIEDINDNAPLFPSTVINISIPENTAINSRYSVPSAIDPDIGVNGIQHYELLKPKTAPKRTFGSITNDQGQNVFGLDIIETPEGDKWPQLIVQQILDREQKDTYVMKIKVEDGGSPPRSSTAILQVTVTDVNDNRPVFKENDIEVSIPENAPVGTSVSQLHATDADLGSNAQIHFYFSNQISSLAKKLFAIDNATGLITIREPLDREESPVHKLTVLASDGSSTPSRATVTVNVTDINDNVPSIDTRYIINPVNGTVLLSEKAPLNTKIALITVMDKDSDLNGKVTCFTDHDVPFRLKPVFDNQFLLETATFLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTQPIIGLSIPENNAPGTQLTKISATDADSGRNAEISYILGSDAPPIFNLDRRTGILTAVRKLDREKQDRYSFTVLAKDNGMPPLQTNATVTVSVLDQNDNSPAFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAAVTLSILNGRDNFIIDPLTGVIRPNITFDREQQGSYTFQVKAVDGGRLQRSSTAKVTINVVDVNDNRPVFVIPSSNYSYELVPTSSSPGSVVTKVFAVDNDTGMNAELRYSIIGGNSRGLFAIDQLTGNITLKEKVITSDHGLHRLVIKVNDLGQPESLYTIALVHLFVNETVTNSSYIQELVRRNMETPVGQNIGDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKNKQSGEWVSPNQENRQIKKKKKKKKRSPKSLLLNFVTIEESKPDDPGHEHINGTLDIPVELEEQTMGKYNWATTPTTFKPDSPDLAKHYKSASPQPTFQIKPETPVPPKKHHVIQELPLDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGGFKTPGPIHTRQHTKEMGRPQTPLKESTLEPWTQPQPQRRVTFHLPDGSQESCSDSGLGDHEPSSGASTSHPLPLGFPQEEYYEQASPNSRTEGDGNSDPESTIEVNLQKALAEASETCTQECLILGHSDNCWMPPSLTQYQQSNTPLPSFGFQQSWGRGARSDGRHTLGRPLPKDDTDKGQGGPRPQFYNTCERHCTSEDPVKVIPLANFAMSHQAAVSGSSTTFIHEHQL", "length": 1245, "header": "tr|A0A1D5NTP6-1|A0A1D5NTP6_CHICK Isoform 1 of Protocadherin 11 X-linked OS=Gallus gallus OX=9031 GN=PCDH11X PE=4 SV=2 CANONICAL=A0A1D5NTP6-1" }, "locus": { "chromosome": "4", "start_pos": 6923596, "end_pos": 6522960, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043738.1", "url": "https://www.ensembl.org/id/ENSGALT00010043738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026021.1", "url": "https://www.ensembl.org/id/ENSGALP00010026021.1" } ] } }, { "isoform_ac": "A0A8V0Z4I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I8/entry", "sequence": { "sequence": "MDLLSGTYLLAVLLACIVFQSGAQEKNYTVREELPENVLIGNLLKDLNLTLDPDVPLSSPLQFKLVYKTGDVPLVRVEENTGEIFTTANRIDREKLCSGIFSENRCFYEVEVAVLPDEVFRLVKIRFLIEDINDNAPLFPSTVINISIPENTAINSRYSVPSAIDPDIGVNGIQHYELLKPKTAPKRTFGSITNDQGQNVFGLDIIETPEGDKWPQLIVQQILDREQKDTYVMKIKVEDGGSPPRSSTAILQVTVTDVNDNRPVFKENDIEVSIPENAPVGTSVSQLHATDADLGSNAQIHFYFSNQISSLAKKLFAIDNATGLITIREPLDREESPVHKLTVLASDGSSTPSRATVTVNVTDINDNVPSIDTRYIINPVNGTVLLSEKAPLNTKIALITVMDKDSDLNGKVTCFTDHDVPFRLKPVFDNQFLLETATFLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTQPIIGLSIPENNAPGTQLTKISATDADSGRNAEISYILGSDAPPIFNLDRRTGILTAVRKLDREKQDRYSFTVLAKDNGMPPLQTNATVTVSVLDQNDNSPAFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAAVTLSILNGRDNFIIDPLTGVIRPNITFDREQQGSYTFQVKAVDGGRLQRSSTAKVTINVVDVNDNRPVFVIPSSNYSYELVPTSSSPGSVVTKVFAVDNDTGMNAELRYSIIGGNSRGLFAIDQLTGNITLKEKVITSDHGLHRLVIKVNDLGQPESLYTIALVHLFVNETVTNSSYIQELVRRNMETPVGQNIGDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKNKQSGEWVSPNQENRQIKKKKKKKKRSPKSLLLNFVTIEESKPDDPGHEHINGTLDIPVELEEQTMGKYNWATTPTTFKPDSPDLAKHYKSASPQPTFQIKPETPVPPKKHHVIQELPLDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGGFKTPGPIHTRQEPVSSCISSHLQSS", "length": 1039, "header": "tr|A0A8V0Z4I8-1|A0A1D5NTP6_CHICK Computationally mapped isoform of Protocadherin 11 X-linked OS=Gallus gallus OX=9031 GN=PCDH11X PE=4 SV=1 CANONICAL=A0A1D5NTP6-1" }, "locus": { "chromosome": "4", "start_pos": 6923596, "end_pos": 6795665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043741.1", "url": "https://www.ensembl.org/id/ENSGALT00010043741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026023.1", "url": "https://www.ensembl.org/id/ENSGALP00010026023.1" } ] } }, { "isoform_ac": "E1BVK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BVK1/entry", "sequence": { "sequence": "MDLLSGTYLLAVLLACIVFQSGAQEKNYTVREELPENVLIGNLLKDLNLTLDPDVPLSSPLQFKLVYKTGDVPLVRVEENTGEIFTTANRIDREKLCSGIFSENRCFYEVEVAVLPDEVFRLVKIRFLIEDINDNAPLFPSTVINISIPENTAINSRYSVPSAIDPDIGVNGIQHYELLKPKTAPKRTFGSITNDQGQNVFGLDIIETPEGDKWPQLIVQQILDREQKDTYVMKIKVEDGGSPPRSSTAILQVTVTDVNDNRPVFKENDIEVSIPENAPVGTSVSQLHATDADLGSNAQIHFYFSNQISSLAKKLFAIDNATGLITIREPLDREESPVHKLTVLASDGSSTPSRATVTVNVTDINDNVPSIDTRYIINPVNGTVLLSEKAPLNTKIALITVMDKDSDLNGKVTCFTDHDVPFRLKPVFDNQFLLETATFLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTQPIIGLSIPENNAPGTQLTKISATDADSGRNAEISYILGSDAPPIFNLDRRTGILTAVRKLDREKQDRYSFTVLAKDNGMPPLQTNATVTVSVLDQNDNSPAFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAAVTLSILNGRDNFIIDPLTGVIRPNITFDREQQGSYTFQVKAVDGGRLQRSSTAKVTINVVDVNDNRPVFVIPSSNYSYELVPTSSSPGSVVTKVFAVDNDTGMNAELRYSIIGGNSRGLFAIDQLTGNITLKEKVITSDHGLHRLVIKVNDLGQPESLYTIALVHLFVNETVTNSSYIQELVRRNMETPVGQNIGDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKNKQSGEWVSPNQENRQIKKKKKKKKRSPKSLLLNFVTIEESKPDDPGHEHINGTLDIPVELEEQTMGKYNWATTPTTFKPDSPDLAKHYKSASPQPTFQIKPETPVPPKKHHVIQELPLDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGGFKTPGPIHTRQL", "length": 1026, "header": "tr|E1BVK1-1|A0A1D5NTP6_CHICK Computationally mapped isoform of Protocadherin 11 X-linked OS=Gallus gallus OX=9031 GN=PCDH11X PE=4 SV=4 CANONICAL=A0A1D5NTP6-1" }, "locus": { "chromosome": "4", "start_pos": 6923596, "end_pos": 6899682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043732.1", "url": "https://www.ensembl.org/id/ENSGALT00010043732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026019.1", "url": "https://www.ensembl.org/id/ENSGALP00010026019.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTP6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A1D5NTP6" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 139, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 794, "end_pos": 796 }, { "start_pos": 915, "end_pos": 917 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P175-1", "uniprot_ac": "A0A1D5P175", "uniprot_id": "A0A1D5P175_CHICK", "mass": { "chemical_mass": 33791.0, "monoisotopic_mass": 33791.0 }, "refseq": { "ac": "NP_001384112", "name": "neuronal membrane glycoprotein M6-b isoform c", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" }, "gene_names": [ { "name": "GPM6B", "type": "recommended", "evidence": [ { "id": "A0A1D5P175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ] }, { "name": "GPM6B", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] }, { "name": "M6b", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] } ], "protein_names": [ { "name": "DMgamma", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] }, { "name": "Glycoprotein M6B", "type": "synonym", "evidence": [ { "id": "A0A1D5P175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175/entry#names_and_taxonomy" } ] }, { "name": "neuronal membrane glycoprotein M6-b isoform c", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] }, { "name": "neuronal membrane glycoprotein M6-b", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] }, { "name": "proteolipid GPM6B", "type": "synonym", "evidence": [ { "id": "NP_001384112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01008953.1, ERR2368565.152926.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000023.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPM6B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175", "locus": { "chromosome": "1", "start_pos": 123058426, "end_pos": 122952088, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002393", "url": "https://www.ensembl.org/id/ENSGALG00010002393" } ] } } ], "crossref": [ { "id": "A0A1D5P175", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P175", "database": "AlphaFoldDB", 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"tr|A0A1D5P175-1|A0A1D5P175_CHICK Isoform 1 of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P175-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175/entry", "sequence": { "sequence": "MKPAMETAAEENAEQSQEKKVITRPEMEIGRYHWMYRSSRPHRYHHVPALRGNVSPLGIQGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 305, "header": "tr|A0A1D5P175-1|A0A1D5P175_CHICK Isoform 1 of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 123028337, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005494.1", "url": "https://www.ensembl.org/id/ENSGALT00010005494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003333.1", "url": "https://www.ensembl.org/id/ENSGALP00010003333.1" } ] } }, { "isoform_ac": "A0A8V0X5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5K5/entry", "sequence": { "sequence": "MITRPEMEIGRYHWMYRSSRPHRYHHVPALRGNVSPLGIQGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 285, "header": "tr|A0A8V0X5K5-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 123029218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005493.1", "url": "https://www.ensembl.org/id/ENSGALT00010005493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003332.1", "url": "https://www.ensembl.org/id/ENSGALP00010003332.1" } ] } }, { "isoform_ac": "A0A8V0X5K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5K9/entry", "sequence": { "sequence": "MFGCSFTTGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLKDASKMQAYQDIKAKEEQELQDIQSRSKEQLNSYT", "length": 276, "header": "tr|A0A8V0X5K9-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123056651, "end_pos": 122971259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005498.1", "url": "https://www.ensembl.org/id/ENSGALT00010005498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003337.1", "url": "https://www.ensembl.org/id/ENSGALP00010003337.1" } ] } }, { "isoform_ac": "A0A8V0X9M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9M0/entry", "sequence": { "sequence": "MSCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 246, "header": "tr|A0A8V0X9M0-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 123012108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005497.1", "url": "https://www.ensembl.org/id/ENSGALT00010005497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003336.1", "url": "https://www.ensembl.org/id/ENSGALP00010003336.1" } ] } }, { "isoform_ac": "A0A8V0XCM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCM2/entry", "sequence": { "sequence": "MKPAMETAAEENAEQSQEKKGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 265, "header": "tr|A0A8V0XCM2-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 123028337, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005495.1", "url": "https://www.ensembl.org/id/ENSGALT00010005495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003334.1", "url": "https://www.ensembl.org/id/ENSGALP00010003334.1" } ] } }, { "isoform_ac": "A0A8V0XFC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC6/entry", "sequence": { "sequence": "MHCALHCQIPEKESSVITRPEMEIGRYHWMYRSSRPHRYHHVPALRGNVSPLGIQGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLKDASKMQAYQDIKAKEEQELQDIQSRSKEQLNSYT", "length": 323, "header": "tr|A0A8V0XFC6-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123056651, "end_pos": 123030822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005501.1", "url": "https://www.ensembl.org/id/ENSGALT00010005501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003340.1", "url": "https://www.ensembl.org/id/ENSGALP00010003340.1" } ] } }, { "isoform_ac": "A0A8V0XG63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG63/entry", "sequence": { "sequence": "MPFCFHQEKCDCCAHFPHGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 263, "header": "tr|A0A8V0XG63-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=1 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 122960742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005499.1", "url": "https://www.ensembl.org/id/ENSGALT00010005499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003338.1", "url": "https://www.ensembl.org/id/ENSGALP00010003338.1" } ] } }, { "isoform_ac": "F6V444-1", "url": "https://www.uniprot.org/uniprotkb/F6V444/entry", "sequence": { "sequence": "MVITRPEMEIGRYHWMYRSSRPHRYHHVPALRGNVSPLGIQGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTVSILEQHFSTTASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSLQINMTVPGDQICVDIRQYGIIPWNAVPGKACGPILENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF", "length": 286, "header": "tr|F6V444-1|A0A1D5P175_CHICK Computationally mapped isoform of Glycoprotein M6B OS=Gallus gallus OX=9031 GN=GPM6B PE=3 SV=2 CANONICAL=A0A1D5P175-1" }, "locus": { "chromosome": "1", "start_pos": 123054975, "end_pos": 122952262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005500.1", "url": "https://www.ensembl.org/id/ENSGALT00010005500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003339.1", "url": "https://www.ensembl.org/id/ENSGALP00010003339.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "myelin sheath", "id": "GO:0043209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of myelin sheath", "id": "GO:0019911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019911", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "extracellular matrix assembly", "id": "GO:0085029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085029", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "central nervous system myelination", "id": "GO:0022010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P175", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P175" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUM3-1", "uniprot_ac": "A0A1D5NUM3", "uniprot_id": "A0A1D5NUM3_CHICK", "mass": { "chemical_mass": 13123.0, "monoisotopic_mass": 13123.0 }, "refseq": { "ac": "NP_001265029", "name": "mth938 domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" }, "gene_names": [ { "name": "AAMDC", "type": "recommended", "evidence": [ { "id": "A0A1D5NUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3" } ] }, { "name": "AAMDC", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "C11orf6", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "C1H11ORF67", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "CK067", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "PTD015", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] } ], "protein_names": [ { "name": "Mth938 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5NUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3/entry#names_and_taxonomy" } ] }, { "name": "UPF0366 protein C11orf67", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "adipogenesis associated Mth938 domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] }, { "name": "mth938 domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001265029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX930541.1, HAEL01011812.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000028.1. On or before May 10, 2013 this sequence version replaced XP_003640647.1, XP_003640648.1, XP_424622.1. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AAMDC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3", "locus": { "chromosome": "1", "start_pos": 192798019, "end_pos": 192811409, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002039", "url": "https://www.ensembl.org/id/ENSGALG00010002039" } ] } } ], "crossref": [ { "id": "A0A1D5NUM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041949", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041949", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425610", "url": "https://www.ncbi.nlm.nih.gov/gene/425610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425610", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AEYNKMA", "url": "https://omabrowser.org/oma/group/AEYNKMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUM3", "url": "https://www.orthodb.org/?gene=A0A1D5NUM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X4E1", "url": "https://www.orthodb.org/?gene=A0A8V0X4E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X840", "url": "https://www.orthodb.org/?gene=A0A8V0X840", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XB66", "url": "https://www.orthodb.org/?gene=A0A8V0XB66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEF5", "url": "https://www.orthodb.org/?gene=A0A8V0XEF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15811", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15811", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15811:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15811:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04430", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04430", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001265029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X840", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X840", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X840-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X840-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNHSPGVQPADLEEVVKKGVKTLVIGRGMSEALQVPPSTVDYLKKNGIDVLVLQTEKAVAEYNALAAQGVKVGGVFHSTC", "length": 122, "header": "tr|A0A1D5NUM3-1|A0A1D5NUM3_CHICK Isoform 1 of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3/entry", "sequence": { "sequence": "MSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNHSPGVQPADLEEVVKKGVKTLVIGRGMSEALQVPPSTVDYLKKNGIDVLVLQTEKAVAEYNALAAQGVKVGGVFHSTC", "length": 122, "header": "tr|A0A1D5NUM3-1|A0A1D5NUM3_CHICK Isoform 1 of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "locus": { "chromosome": "1", "start_pos": 192808895, "end_pos": 192804626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004616.1", "url": "https://www.ensembl.org/id/ENSGALT00010004616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002801.1", "url": "https://www.ensembl.org/id/ENSGALP00010002801.1" } ] } }, { "isoform_ac": "A0A8V0X4E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E1/entry", "sequence": { "sequence": "MSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNHSPGVQPADLEEVVKKGVKTLVIGRGMSEALQGNEPRMLKSNGNNWAATHAAFQASALKVKHKQYVRGFLKQLNVFWSEAS", "length": 125, "header": "tr|A0A8V0X4E1-1|A0A1D5NUM3_CHICK Computationally mapped isoform of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "locus": { "chromosome": "1", "start_pos": 192808895, "end_pos": 192800828, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004610.1", "url": "https://www.ensembl.org/id/ENSGALT00010004610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002799.1", "url": "https://www.ensembl.org/id/ENSGALP00010002799.1" } ] } }, { "isoform_ac": "A0A8V0X840-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X840/entry", "sequence": { "sequence": "MSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNHSPGVQPADLEEVVKKGVKTLVIGRGMSEALQAGQKCCVLLTKFCCLHQLPAVTTHALSQLSQLQHSCTGHISGCSLRQLAVPLGDSFPTPGQQHFTIIFAFAKQTDTNAQVSENYKSTDLCA", "length": 167, "header": "tr|A0A8V0X840-1|A0A1D5NUM3_CHICK Computationally mapped isoform of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "locus": { "chromosome": "1", "start_pos": 192808895, "end_pos": 192800280, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004620.1", "url": "https://www.ensembl.org/id/ENSGALT00010004620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002803.1", "url": "https://www.ensembl.org/id/ENSGALP00010002803.1" } ] } }, { "isoform_ac": "A0A8V0XB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB66/entry", "sequence": { "sequence": "MLCIKYLFFRLRFNAVMSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNHSPGVQPADLEEVVKKGVKTLVIGRGMSEALQAGQKCCVLLTKFCCLHQLPAVTTHALSQLSQLQHSCTGHISGCSLRQLAVPLGDSFPTPGQQHFTIIFAFAKQTDTNAQVSENYKSTDLCA", "length": 183, "header": "tr|A0A8V0XB66-1|A0A1D5NUM3_CHICK Computationally mapped isoform of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "locus": { "chromosome": "1", "start_pos": 192808943, "end_pos": 192800280, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004603.1", "url": "https://www.ensembl.org/id/ENSGALT00010004603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002796.1", "url": "https://www.ensembl.org/id/ENSGALP00010002796.1" } ] } }, { "isoform_ac": "A0A8V0XEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEF5/entry", "sequence": { "sequence": "MSSPEIASLSWGQMKVKGCSTTYKDCKVWPGGSRTWDWRETGTNAGQKCCVLLTKFCCLHQLPAVTTHALSQLSQLQHSCTGHISGCSLRQLAVPLGDSFPTPGQQHFTIIFAFAKQTDTNAQVSENYKSTDLCA", "length": 135, "header": "tr|A0A8V0XEF5-1|A0A1D5NUM3_CHICK Computationally mapped isoform of Mth938 domain-containing protein OS=Gallus gallus OX=9031 GN=AAMDC PE=3 SV=1 CANONICAL=A0A1D5NUM3-1" }, "locus": { "chromosome": "1", "start_pos": 192808895, "end_pos": 192800280, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004613.1", "url": "https://www.ensembl.org/id/ENSGALT00010004613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002800.1", "url": "https://www.ensembl.org/id/ENSGALP00010002800.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425610", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHU8-1", "protein_name": "Mth938 domain-containing protein", "gene_name": "Aamdc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASGQADMVLEEPRVLHLDPKISVHMLMASPKIASLSWGQMKVQGSTLTYKDCKVWPGGSRAWDWRETGTEHSPGVQPADVKEVAEKGVQTLVIGRGMSEALKVPPSTVEYLEKQGIDVRVLQTEQAVKEYNALAARGIRVGGVFHSTC", "length": 150 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FEE0-1", "protein_name": "Adiposis associated Mth938 domain containing", "gene_name": "AAMDC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSPEIASLSWGQMKVQGSTKIYKDCKVWPGGSRAWDWRETGTEVPVSTVEYLKKKGIDVRVLQTEQAVKEYNALVTQGLRVGGVFHSTC", "length": 90 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32PA8-1", "protein_name": "Mth938 domain-containing protein", "gene_name": "AAMDC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSPEIASLSWGQMKVQGSTKIYKDCKVWPGGSRDWDWRETGTEHSPGVQPADVEEVVEKGVQILVIGRGMSEALKVPPSTVEYLKKKGIDVRVLQTEQAVKEYNALATQGIRVGGVFHSTC", "length": 122 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q502H1-1", "protein_name": "Mth938 domain-containing protein", "gene_name": "aamdc", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSPEIASLSWGHMKVKGCSTSYKDCKVWPGGSRAWDWRETGTNHHPGVQPSDLEEILRKGVQTLVIGRGMSEALQVPPSTLDYVKKQGVDVQVFQTEQAVREYNALAGKGEKVGGVFHSTC", "length": 122 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R0P4-1", "protein_name": "Mth938 domain-containing protein", "gene_name": "Aamdc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPKIASLSWGQMKVQGSTLTYKDCKVWPGGSRAWDWRETGTEHSPGVQPADVKEVAEKGVQTLVIGRGMSEALKVPPSTVEYLEKQGIDVRVLQTEQAVKEYNALVAQGVRVGGVFHSTC", "length": 122 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H7C9-1", "protein_name": "Mth938 domain-containing protein", "gene_name": "AAMDC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPEIASLSWGQMKVKGSNTTYKDCKVWPGGSRTWDWRETGTEHSPGVQPADVKEVVEKGVQTLVIGRGMSEALKVPSSTVEYLKKHGIDVRVLQTEQAVKEYNALVAQGVRVGGVFHSTC", "length": 122 }, "evidence": [ { "id": "A0A1D5NUM3", "url": "https://omabrowser.org/oma/group/A0A1D5NUM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVQ9-1", "uniprot_ac": "A0A1D5NVQ9", "uniprot_id": "A0A1D5NVQ9_CHICK", "mass": { "chemical_mass": 58074.0, "monoisotopic_mass": 58074.0 }, "refseq": { "ac": "XP_004939906", "name": "gamma-1-syntrophin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906" }, "gene_names": [ { "name": "SNTG1", "type": "recommended", "evidence": [ { "id": "A0A1D5NVQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ] }, { "name": "SNTG1", "type": "synonym", "evidence": [ { "id": "XP_004939906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906" } ] } ], "protein_names": [ { "name": "Gamma-1-syntrophin", "type": "recommended", "evidence": [ { "id": "A0A1D5NVQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9/entry#names_and_taxonomy" } ] }, { "name": "Syntrophin-4", "type": "synonym", "evidence": [ { "id": "A0A1D5NVQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9/entry#names_and_taxonomy" } ] }, { "name": "gamma-1-syntrophin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004939906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906" } ] }, { "annotation": "Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9#function" }, { "database": "UniProtKB", "id": "ARBA00057519", "url": "https://www.uniprot.org/uniprotkb/ARBA00057519#function" }, { "database": "UniProtKB", "id": "A0A8V0XI59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI59#function" }, { "database": "UniProtKB", "id": "A0A8V0XKW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW2#function" }, { "database": "UniProtKB", "id": "A0A8V0XKW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNTG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9", "locus": { "chromosome": "2", "start_pos": 108781058, "end_pos": 108439440, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003965", "url": "https://www.ensembl.org/id/ENSGALG00010003965" } ] } } ], "crossref": [ { "id": "A0A1D5NVQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015248", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00821", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00821", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421113", "url": "https://www.ncbi.nlm.nih.gov/gene/421113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421113", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVTRYLW", "url": "https://omabrowser.org/oma/group/YVTRYLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NVQ9", "url": "https://www.orthodb.org/?gene=A0A1D5NVQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004939906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFRTTCEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 517, "header": "tr|A0A1D5NVQ9-1|A0A1D5NVQ9_CHICK Isoform 1 of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9/entry", "sequence": { "sequence": "MDFRTTCEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 517, "header": "tr|A0A1D5NVQ9-1|A0A1D5NVQ9_CHICK Isoform 1 of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108767831, "end_pos": 108616115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009178.1", "url": "https://www.ensembl.org/id/ENSGALT00010009178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005422.1", "url": "https://www.ensembl.org/id/ENSGALP00010005422.1" } ] } }, { "isoform_ac": "A0A8V0XBC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBC0/entry", "sequence": { "sequence": "MDFRTTCEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 503, "header": "tr|A0A8V0XBC0-1|A0A1D5NVQ9_CHICK Computationally mapped isoform of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108767831, "end_pos": 108616115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009180.1", "url": "https://www.ensembl.org/id/ENSGALT00010009180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005423.1", "url": "https://www.ensembl.org/id/ENSGALP00010005423.1" } ] } }, { "isoform_ac": "A0A8V0XI59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI59/entry", "sequence": { "sequence": "MDFRTTCEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGASNMESIINVILNKKCMSF", "length": 528, "header": "tr|A0A8V0XI59-1|A0A1D5NVQ9_CHICK Computationally mapped isoform of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108781037, "end_pos": 108616115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009183.1", "url": "https://www.ensembl.org/id/ENSGALT00010009183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005425.1", "url": "https://www.ensembl.org/id/ENSGALP00010005425.1" } ] } }, { "isoform_ac": "A0A8V0XKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW2/entry", "sequence": { "sequence": "TLRSEVLFNERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 472, "header": "tr|A0A8V0XKW2-1|A0A1D5NVQ9_CHICK Computationally mapped isoform of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108767831, "end_pos": 108630422, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009174.1", "url": "https://www.ensembl.org/id/ENSGALT00010009174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005421.1", "url": "https://www.ensembl.org/id/ENSGALP00010005421.1" } ] } }, { "isoform_ac": "A0A8V0XKW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKW9/entry", "sequence": { "sequence": "SVCLERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKDSDLLDRRKHCFGVQSESGEDLYFSVELESDLALWEKAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 467, "header": "tr|A0A8V0XKW9-1|A0A1D5NVQ9_CHICK Computationally mapped isoform of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108767831, "end_pos": 108627347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009186.1", "url": "https://www.ensembl.org/id/ENSGALT00010009186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005426.1", "url": "https://www.ensembl.org/id/ENSGALP00010005426.1" } ] } }, { "isoform_ac": "A0A8V0XMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH7/entry", "sequence": { "sequence": "MDFRTTCEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPGSDLCRQNAFQVIAVDGVCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWTEEREQDSLQDRMYTPKFLALRGSSLYKFMAPPVTTWDWTRAEKTFSVYEIMCKIFKCKTYACVLESHLMGLTIDFSTGFVCFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDNKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATASAAPTTSGTGKLKYTT", "length": 466, "header": "tr|A0A8V0XMH7-1|A0A1D5NVQ9_CHICK Computationally mapped isoform of Gamma-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTG1 PE=3 SV=1 CANONICAL=A0A1D5NVQ9-1" }, "locus": { "chromosome": "2", "start_pos": 108767831, "end_pos": 108616115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009181.1", "url": "https://www.ensembl.org/id/ENSGALT00010009181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005424.1", "url": "https://www.ensembl.org/id/ENSGALP00010005424.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421113", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U8R9-1", "protein_name": "Gamma-1-syntrophin", "gene_name": "SNTG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFRTACEETKTGICLLQDGAQEPFKVRLHLAKDLLMIQEQDVICVSGEPFYSGERTVTIRRQAVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNFHPNNTDTLSCSSWPASPGLRWEKRWCDLRLIPLLHSRFSQYVPGTDLSRQNAFQVTAVDGVCSGIIQCLSAEDSLDWLQAIATNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQDALQDRVYLPTFLALRGSCLYKFLAPPVTTWDWTRAEKTFSVYEIMCKILKDSDLLDRRKHCFTVQSESGEDLYFSVELDSDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFICFDAATKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGSQAAASAASSSSMSSKAKSLT", "length": 480 }, "evidence": [ { "id": "A0A1D5NVQ9", "url": "https://omabrowser.org/oma/group/A0A1D5NVQ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1ZAH3-1", "protein_name": "Syntrophin-like 2, isoform E", "gene_name": "Syn2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MISGIMKLSDTMATPIEEKLDQNLKVRTGMVHVSDGKSRPEPLRLNLTMELLSLQKLEVVTPSSCHPNGPPMESKERMVQITRQKQGGLGLSIKGGAEHKLPILISRIYKDQAADITGQLFVGDAIIKVNGEYITACPHDDAVNILRNAGDIVVLTVKHYRAATPFLQKQLTKDTPDSDNDVTCAELKADEGYKSSVNSGTISRSCSRPMSICSEPEKRWTDVVAVPLMMAYVTRYIYGTDKLRQNAFEVRGLNGISTGVIHCDELAILSQWLKLITDNVVGLTHLQMKLYNRNFAVGERIEYMGWVNEGVINNNISWQSYKPRFLLLKGTEVMLFETPPLNVAGISKALVVYKVYQTMFRIVKESETVDSRQHCFLLQSSGHEPRYLSVETRQELLRIENSWNAAIVTSVIKLGRKTFAVSHHGKSGGLTLDWQAGFSLTEGAESATVWQYKFSQLRGSSDDGKSKLKLHFQDHDSRAIETKELECQVLQSLLFCMHAFLTAKVASVDPAFLSSIQQT", "length": 519 }, "evidence": [ { "id": "A0A1D5NVQ9", "url": "https://omabrowser.org/oma/group/A0A1D5NVQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "syntrophin complex", "id": "GO:0016013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P442-1", "uniprot_ac": "A0A1D5P442", "uniprot_id": "A0A1D5P442_CHICK", "mass": { "chemical_mass": 41645.0, "monoisotopic_mass": 41645.0 }, "refseq": { "ac": "XP_420576", "name": "trans-2,3-enoyl-CoA reductase-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420576" }, "gene_names": [ { "name": "TECRL", "type": "recommended", "evidence": [ { "id": "A0A1D5P442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ] }, { "name": "TECRL", "type": "synonym", "evidence": [ { "id": "XP_420576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420576" } ] } ], "protein_names": [ { "name": "Trans-2,3-enoyl-CoA reductase-like", "type": "recommended", "evidence": [ { "id": "A0A1D5P442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442/entry#names_and_taxonomy" } ] }, { "name": "Steroid 5-alpha-reductase 2-like 2 protein", "type": "synonym", "evidence": [ { "id": "A0A1D5P442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442/entry#names_and_taxonomy" } ] }, { "name": "trans-2,3-enoyl-CoA reductase-like", "type": "synonym", "evidence": [ { "id": "XP_420576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TECRL", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442", "locus": { "chromosome": "4", "start_pos": 48587351, "end_pos": 48642364, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003632", "url": "https://www.ensembl.org/id/ENSGALG00010003632" } ] } } ], "crossref": [ { "id": "A0A1D5P442", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P442", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038771", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422618", "url": "https://www.ncbi.nlm.nih.gov/gene/422618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422618", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422618", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQVSWTT", "url": "https://omabrowser.org/oma/group/RQVSWTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P442", "url": "https://www.orthodb.org/?gene=A0A1D5P442", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGY7", "url": "https://www.orthodb.org/?gene=A0A8V0XGY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJN5", "url": "https://www.orthodb.org/?gene=A0A8V0XJN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XL47", "url": "https://www.orthodb.org/?gene=A0A8V0XL47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10556", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10556", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10556:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10556:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75876", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P442-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XL47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRRKTSASELKRDLSAHGGALSMSQNTRTFFNFSQLVLSAGHLKPPPVLKHSKVTYFEVEILDVQSKKQICIVDKIPPSSTLLDVKHKFHKACPQWYPSRVGLQLERNGPYLKDSVNIQSLAASSIITLYFTDLGQQVGWTTFFLTEYTGPLLIYLLFYIRLSTIYDQVESTKNFRHPVVHLACFCHCLHYIRHLLETLFVHKFSGGHTPLKNMIKGCVFYWGFTSWIAYYINHPRYTPPSFGHRQVSLAALAFLMCEAGNHFINVALAHQNHSGNKACFPSPTYNPFTWLFLLVSCPNYTYEVGSWISFTVMTQTLPVGIFAFLMVIQMSLWAQKKHKLYLKKFYPEVRRKAAMIPIVF", "length": 362, "header": "tr|A0A1D5P442-1|A0A1D5P442_CHICK Isoform 1 of Trans-2,3-enoyl-CoA reductase-like OS=Gallus gallus OX=9031 GN=TECRL PE=3 SV=2 CANONICAL=A0A1D5P442-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P442-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442/entry", "sequence": { "sequence": "MLRRRKTSASELKRDLSAHGGALSMSQNTRTFFNFSQLVLSAGHLKPPPVLKHSKVTYFEVEILDVQSKKQICIVDKIPPSSTLLDVKHKFHKACPQWYPSRVGLQLERNGPYLKDSVNIQSLAASSIITLYFTDLGQQVGWTTFFLTEYTGPLLIYLLFYIRLSTIYDQVESTKNFRHPVVHLACFCHCLHYIRHLLETLFVHKFSGGHTPLKNMIKGCVFYWGFTSWIAYYINHPRYTPPSFGHRQVSLAALAFLMCEAGNHFINVALAHQNHSGNKACFPSPTYNPFTWLFLLVSCPNYTYEVGSWISFTVMTQTLPVGIFAFLMVIQMSLWAQKKHKLYLKKFYPEVRRKAAMIPIVF", "length": 362, "header": "tr|A0A1D5P442-1|A0A1D5P442_CHICK Isoform 1 of Trans-2,3-enoyl-CoA reductase-like OS=Gallus gallus OX=9031 GN=TECRL PE=3 SV=2 CANONICAL=A0A1D5P442-1" }, "locus": { "chromosome": "4", "start_pos": 48641716, "end_pos": 48589433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008437.1", "url": "https://www.ensembl.org/id/ENSGALT00010008437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004962.1", "url": "https://www.ensembl.org/id/ENSGALP00010004962.1" } ] } }, { "isoform_ac": "A0A8V0XGY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY7/entry", "sequence": { "sequence": "MLRRRKTSASELKRDLSAHGGALSMSQNTRTFFNFSQLVLSAGHLKPPPVLKHSKVTYFEVEILDVQSKKQICIVDKIPPSSTLLDVKHKFHKASDTNGRLSYIECPQWYPSRVGLQLERNGPYLKDSVNIQSLAASSIITLYFTDLGQQVGWTTFFLTEYTGPLLIYLLFYIRLSTIYDQVESTKNFRHPVVHLACFCHCLHYIRHLLETLFVHKFSGGHTPLKNMIKGCVFYWGFTSWIAYYINHPRYTPPSFGHRQVSLAALAFLMCEAGNHFINVALAHQNHSGNKACFPSPTYNPFTWLFLLVSCPNYTYEVGSWISFTVMTQTLPVGIFAFLMVIQMSLWAQKKHKLYLKKFYPEVRRKAAMIPIVF", "length": 373, "header": "tr|A0A8V0XGY7-1|A0A1D5P442_CHICK Computationally mapped isoform of Trans-2,3-enoyl-CoA reductase-like OS=Gallus gallus OX=9031 GN=TECRL PE=3 SV=1 CANONICAL=A0A1D5P442-1" }, "locus": { "chromosome": "4", "start_pos": 48641716, "end_pos": 48589433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008430.1", "url": "https://www.ensembl.org/id/ENSGALT00010008430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004958.1", "url": "https://www.ensembl.org/id/ENSGALP00010004958.1" } ] } }, { "isoform_ac": "A0A8V0XJN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN5/entry", "sequence": { "sequence": "MLRRRKTSASELKRDLSAHGGALSMSQNTRTFFNFSQLVLSAGHLKPPPVLKHSKVTYFEVEILDVQSKKQICIVDKIPPSSTLLDVKHKFHKACPQWYPSRVGLQLERNGPYLKDSVNIQSLAASSIITLYFTDLGQQVGWTTFFLTEYTGPLLIYLLFYIRLSTIYDQVESTKNFRHPVVHLACFCHCLHYIRHLLETLFVHKFSGGHTPLKNMIKGCVFYWGFTSWIAYYINHPRYTPPSFGHRQVSLAALAFLETKPVFQVQPTTPSRGSSCWYPVPTILMSWHLCFPDGHPDVSLGPKETQAVPEEILSRGAEKSSYDSYCLLSSW", "length": 331, "header": "tr|A0A8V0XJN5-1|A0A1D5P442_CHICK Computationally mapped isoform of Trans-2,3-enoyl-CoA reductase-like OS=Gallus gallus OX=9031 GN=TECRL PE=3 SV=1 CANONICAL=A0A1D5P442-1" }, "locus": { "chromosome": "4", "start_pos": 48641716, "end_pos": 48589422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008424.1", "url": "https://www.ensembl.org/id/ENSGALT00010008424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004954.1", "url": "https://www.ensembl.org/id/ENSGALP00010004954.1" } ] } }, { "isoform_ac": "A0A8V0XL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL47/entry", "sequence": { "sequence": "MLRRRKTSASELKRDLSAHGGALSMSQNTRTFFNFSQLVLSAGHLKPPPVLKHSKVTYFEVEILDVQSKKQICIVDKIPPSSTLLDVKHKFHKACPQWYPSRVGLQLERNGPYLKDSVNIQSLAASSIITLYFTDLGQQVGWTTFFLTEYTGPLLIYLLFYIRLSTIYDQVESTKNFRHPVVHLACFCHCLHYIRHLLETLFVHKFSGGHTPLKNMIKMEAPRKKISSCLKSSVS", "length": 235, "header": "tr|A0A8V0XL47-1|A0A1D5P442_CHICK Computationally mapped isoform of Trans-2,3-enoyl-CoA reductase-like OS=Gallus gallus OX=9031 GN=TECRL PE=3 SV=1 CANONICAL=A0A1D5P442-1" }, "locus": { "chromosome": "4", "start_pos": 48641716, "end_pos": 48599003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008419.1", "url": "https://www.ensembl.org/id/ENSGALT00010008419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004952.1", "url": "https://www.ensembl.org/id/ENSGALP00010004952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422618", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422618", "resource": "KEGG Pathway" }, { "id": "R-GGA-75876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75876", "resource": "Reactome", "description": "Synthesis of very long-chain fatty acyl-CoAs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKRHRSLASERKRELISPGATRSMLKNDMRNFHSLSQFILSAGPLKSIPAVKHAKTIHFEIEILDAQTRKQICIVDKVTQKSTIQDVKQKFHKACPKWYPSRVGLQLERGGPFLKDYRTIQSIAVSSIITLYFTDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPYIYDIKESSRRLRHPVVHLACFCHCIHYLRYLLETLFVHKVSAGHTPLKNLIKSCAFYWGFTSWIAYYINHPRYTPPSFGNKQITVSAINFLICEAGNHFINVMLAHPNHTGSNACFPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLISIQMSLWAQKKHKNYLKKFNSYIHKKSAMIPFIL", "length": 363 }, "evidence": [ { "id": "A0A1D5P442", "url": "https://omabrowser.org/oma/group/A0A1D5P442/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A1Y9-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "Tecrl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKRHKSLERKRELLFQGLPQFTMKNNTRNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIYDVKQKFHKACPKWYPSRIGLQLEYGGPYLKDYITIQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLRSSYIYDVKESFRWPRHTVVHLACFCHCIHYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAYYINHPRYTPPSFGNRQIIVSAINFLMCEAGNHFINTVLAHPSHTGSNACFPSPTYNPFTWMFFLVSCPNYTYEIGTWISFTIMTQTLPVGIFTMLMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPFIL", "length": 361 }, "evidence": [ { "id": "A0A1D5P442", "url": "https://omabrowser.org/oma/group/A0A1D5P442/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SZ89-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFKRHKSLASERRRELISRGATRSILKDDMKNFHFLSQFILSAGPLKSTSAVKHSKTIHFEIEILDAQTKKQICIVDKVTQKSTIHDVKQKFHKACPQWYPSRVGLQLERGGPFLKDNLTIQSVAASSIVTLYFTDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPYIYNMKESSRRLCHPVVHLACFCHCIHYIRYLLETLFVHKVSSGHTSLKNLLKSCAFYWGFTSWIAYYINHPRYTPPSFGYRQVAISAINFLICEAGNHFINVVLSHPSHTGNNACFPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTIMTQTLPVGIFTLLMSIQMSLWAKKKHKIYLKKFSSYMHRKSAMIPFIL", "length": 363 }, "evidence": [ { "id": "A0A1D5P442", "url": "https://omabrowser.org/oma/group/A0A1D5P442/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKWYPSRVGLQLECGGPFLKDYITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLRIPCIYDGKESARRLRHPVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHPLYTPPSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNACFPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIPFIL", "length": 363 }, "evidence": [ { "id": "A0A1D5P442", "url": "https://omabrowser.org/oma/group/A0A1D5P442/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFZ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "Tecrl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKRHKSLERKRELLFQGLPQSTMKNNARNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIHDVKQKFHKACPKWYPSRIGLQLEYGGPYLRDYITVQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLRSSYIYDVKESTRWPRHPVVHLAFFCHCIHYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAYYINHPRYTPPSFGNRQVIVSAINFLFCEAGNHFINTVLAHPNHTGSNACFPSPNYNPFTWLFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTILMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPLIL", "length": 361 }, "evidence": [ { "id": "A0A1D5P442", "url": "https://omabrowser.org/oma/group/A0A1D5P442/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "very-long-chain enoyl-CoA reductase activity", "id": "GO:0102758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102758", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-CH group of donors", "id": "GO:0016627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016627", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P442", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" }, { "id": "PF02544", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02544" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 362, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5P442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P442" }, { "id": "PF21696", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21696" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TECR-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 135, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYA0-1", "uniprot_ac": "A0A1D5NYA0", "uniprot_id": "A0A1D5NYA0_CHICK", "mass": { "chemical_mass": 32584.0, "monoisotopic_mass": 32584.0 }, "refseq": { "ac": "NP_001264444", "name": "protein NipSnap homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264444" }, "gene_names": [ { "name": "NIPSNAP1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ] }, { "name": "NIPSNAP1", "type": "synonym", "evidence": [ { "id": "NP_001264444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264444" } ] } ], "protein_names": [ { "name": "Nipsnap homolog 1", "type": "synonym", "evidence": [ { "id": "A0A1D5NYA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0/entry#names_and_taxonomy" } ] }, { "name": "protein NipSnap homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001264444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264444" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01133458.1, CR387707.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Nov 16, 2021 this sequence version replaced NP_001264444.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264444" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIPSNAP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0", "locus": { "chromosome": "15", "start_pos": 11112530, "end_pos": 11106041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000173", "url": "https://www.ensembl.org/id/ENSGALG00010000173" } ] } } ], "crossref": [ { "id": "A0A1D5NYA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038301", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038301", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417018", "url": "https://www.ncbi.nlm.nih.gov/gene/417018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417018", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NESSWFR", "url": "https://omabrowser.org/oma/group/NESSWFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYA0", "url": "https://www.orthodb.org/?gene=A0A1D5NYA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0WZL3", "url": "https://www.orthodb.org/?gene=A0A8V0WZL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0WZL5", "url": "https://www.orthodb.org/?gene=A0A8V0WZL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X2E9", "url": "https://www.orthodb.org/?gene=A0A8V0X2E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X4M8", "url": "https://www.orthodb.org/?gene=A0A8V0X4M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264444", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARAGGGAVLLRRLQGGGGGGGAFSGARAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 281, "header": "tr|A0A1D5NYA0-1|A0A1D5NYA0_CHICK Isoform 1 of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=2 CANONICAL=A0A1D5NYA0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0/entry", "sequence": { "sequence": "MAAARAGGGAVLLRRLQGGGGGGGAFSGARAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 281, "header": "tr|A0A1D5NYA0-1|A0A1D5NYA0_CHICK Isoform 1 of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=2 CANONICAL=A0A1D5NYA0-1" }, "locus": { "chromosome": "15", "start_pos": 11112218, "end_pos": 11109409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000334.1", "url": "https://www.ensembl.org/id/ENSGALT00010000334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000177.1", "url": "https://www.ensembl.org/id/ENSGALP00010000177.1" } ] } }, { "isoform_ac": "A0A8V0WZL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL3/entry", "sequence": { "sequence": "MQKKAPQPIKNRLLQESPLIGCWHLEARPRGRQPMRSLCGRGNKALAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 297, "header": "tr|A0A8V0WZL3-1|A0A1D5NYA0_CHICK Computationally mapped isoform of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=1 CANONICAL=A0A1D5NYA0-1" }, "locus": { "chromosome": "15", "start_pos": 11112218, "end_pos": 11109077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000339.1", "url": "https://www.ensembl.org/id/ENSGALT00010000339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000182.1", "url": "https://www.ensembl.org/id/ENSGALP00010000182.1" } ] } }, { "isoform_ac": "A0A8V0WZL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZL5/entry", "sequence": { "sequence": "MVWGSNSVTGQDWNQYRENGPCRPVPRVHTFGKGEQAMRRDPHIPPTMRGWLHKQDSSGLRLWKRRWFVLVDLCLYYYRDSSEQRVRGGLPLPGYRIRVLAPSTSSPRFLFTVEHPGMRSYVLGADSPEELGAWMCSLRHSASPMGGAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 398, "header": "tr|A0A8V0WZL5-1|A0A1D5NYA0_CHICK Computationally mapped isoform of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=1 CANONICAL=A0A1D5NYA0-1" }, "locus": { "chromosome": "15", "start_pos": 11112218, "end_pos": 11106425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000344.1", "url": "https://www.ensembl.org/id/ENSGALT00010000344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000187.1", "url": "https://www.ensembl.org/id/ENSGALP00010000187.1" } ] } }, { "isoform_ac": "A0A8V0X2E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2E9/entry", "sequence": { "sequence": "MVGWERGCRSDNETRIGTRTATGIMVWGSNSVTGQDWNQYRENGDSSGLRLWKRRWFVLVDLCLYYYRDSSEQRVRGGLPLPGYRIRVLAPSTSSPRFLFTVEHPGMRSYVLGADSPEELGAWMCSLRHSASPMGGAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 387, "header": "tr|A0A8V0X2E9-1|A0A1D5NYA0_CHICK Computationally mapped isoform of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=1 CANONICAL=A0A1D5NYA0-1" }, "locus": { "chromosome": "15", "start_pos": 11112218, "end_pos": 11106353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000343.1", "url": "https://www.ensembl.org/id/ENSGALT00010000343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000186.1", "url": "https://www.ensembl.org/id/ENSGALP00010000186.1" } ] } }, { "isoform_ac": "A0A8V0X4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4M8/entry", "sequence": { "sequence": "MVGWERGCRSDNETRIGTRTATGIMVWGSNSVTGQDWNQYRENGPCRPVPRVHTFGKGEQAMRRDPHIPPTMRGWLHKQDSSGLRLWKRRWFVLVDLCLYYYRDSSEQRVRGGLPLPGYRIRVLAPSTSSPRFLFTVEHPGMRSYVLGADSPEELGAWMCSLRHSASPMGGAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 422, "header": "tr|A0A8V0X4M8-1|A0A1D5NYA0_CHICK Computationally mapped isoform of Nipsnap homolog 1 OS=Gallus gallus OX=9031 GN=NIPSNAP1 PE=3 SV=1 CANONICAL=A0A1D5NYA0-1" }, "locus": { "chromosome": "15", "start_pos": 11112218, "end_pos": 11106353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000341.1", "url": "https://www.ensembl.org/id/ENSGALT00010000341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000184.1", "url": "https://www.ensembl.org/id/ENSGALP00010000184.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417018", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IQW3-1", "protein_name": "Protein NipSnap homolog 1", "gene_name": "Nipsnap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPRLCIISASARRLLGKPGPRAGDLAAAAAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A1D5NYA0", "url": "https://omabrowser.org/oma/group/A0A1D5NYA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V728-1", "protein_name": "Nipsnap homolog 1", "gene_name": "Nipsnap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRLCIISAAARRLLRKPGPCVGDLAAARAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A1D5NYA0", "url": "https://omabrowser.org/oma/group/A0A1D5NYA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55125-1", "protein_name": "Protein NipSnap homolog 1", "gene_name": "Nipsnap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRLCIISAAARRLFTKPRPRAGDLAAAGAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A1D5NYA0", "url": "https://omabrowser.org/oma/group/A0A1D5NYA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BPW8-1", "protein_name": "Protein NipSnap homolog 1", "gene_name": "NIPSNAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A1D5NYA0", "url": "https://omabrowser.org/oma/group/A0A1D5NYA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" }, { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYA0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"name": "Transmembrane protein 233", "type": "synonym", "evidence": [ { "id": "A0A1D5P1G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 233 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046757361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757361" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757361" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM233", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0", "locus": { "chromosome": "15", "start_pos": 9656333, "end_pos": 9670055, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023343", "url": "https://www.ensembl.org/id/ENSGALG00010023343" } ] } } ], "crossref": [ { "id": "A0A1D5P1G0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P1G0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000020975", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000020975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101748111", "url": "https://www.ncbi.nlm.nih.gov/gene/101748111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748111", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLFCELL", "url": "https://omabrowser.org/oma/group/WLFCELL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1G0", "url": "https://www.orthodb.org/?gene=A0A1D5P1G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZUT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046757361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P1G0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLPAGTDIKRALDNSPETNIEDELPDGPPQPRPKNYLLLSILSCFCPAYPINIVAFVFAVMALNSYNQGDIEGSRRLGRNALWVAVASIIIGLVIIGIYCVVHFTTHAI", "length": 111, "header": "tr|A0A1D5P1G0-1|A0A1D5P1G0_CHICK Isoform 1 of Transmembrane protein 233 OS=Gallus gallus OX=9031 GN=TMEM233 PE=3 SV=2 CANONICAL=A0A1D5P1G0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0/entry", "sequence": { "sequence": "MSSLPAGTDIKRALDNSPETNIEDELPDGPPQPRPKNYLLLSILSCFCPAYPINIVAFVFAVMALNSYNQGDIEGSRRLGRNALWVAVASIIIGLVIIGIYCVVHFTTHAI", "length": 111, "header": "tr|A0A1D5P1G0-1|A0A1D5P1G0_CHICK Isoform 1 of Transmembrane protein 233 OS=Gallus gallus OX=9031 GN=TMEM233 PE=3 SV=2 CANONICAL=A0A1D5P1G0-1" }, "locus": { "chromosome": "15", "start_pos": 9669946, "end_pos": 9658174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056912.1", "url": "https://www.ensembl.org/id/ENSGALT00010056912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034606.1", "url": "https://www.ensembl.org/id/ENSGALP00010034606.1" } ] } }, { "isoform_ac": "A0A8V0ZUT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT5/entry", "sequence": { "sequence": "MSSLPAGTDIKRALDNSPETNIEDELPDGPPQPRPKNYLLLSILSCFCPAYPINIVAFVFAVMALNSYNQGDIEGSRRLGRNALWVAVASIIIGLVIIGIYCVVHFTTPLFFIEVSGAQPVLNYSNTKLHSYQWNELISSALNTDVVCTWRNLAAGFDDPKKWLFCELLLVF", "length": 172, "header": "tr|A0A8V0ZUT5-1|A0A1D5P1G0_CHICK Computationally mapped isoform of Transmembrane protein 233 OS=Gallus gallus OX=9031 GN=TMEM233 PE=3 SV=1 CANONICAL=A0A1D5P1G0-1" }, "locus": { "chromosome": "15", "start_pos": 9669946, "end_pos": 9656451, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056906.1", "url": "https://www.ensembl.org/id/ENSGALT00010056906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034604.1", "url": "https://www.ensembl.org/id/ENSGALP00010034604.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101748111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748111", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1G0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NWF7-1", "uniprot_ac": "A0A1D5NWF7", "uniprot_id": "A0A1D5NWF7_CHICK", "mass": { "chemical_mass": 30683.0, "monoisotopic_mass": 30683.0 }, "refseq": { "ac": "NP_990135", "name": "homeobox protein DLX-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" }, "gene_names": [ { "name": "DLX3", "type": "recommended", "evidence": [ { "id": "A0A1D5NWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7" } ] }, { "name": "DLX3", "type": "synonym", "evidence": [ { "id": "NP_990135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ] } ], "protein_names": [ { "name": "DLX3 homeodomain containing protein", "type": "synonym", "evidence": [ { "id": "NP_990135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ] }, { "name": "Distal-less homeobox 3", "type": "synonym", "evidence": [ { "id": "A0A1D5NWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein DLX-3", "type": "synonym", "evidence": [ { "id": "NP_990135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992484, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000735.1. On Mar 13, 2018 this sequence version replaced NP_990135.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ] }, { "annotation": "Dlx3 gene expression is described in the forebrain of chicken embryos; this constitutes the first documented evidence of expression of either Dlx3 or Dlx4 in the vertebrate central nervous system", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" }, { "database": "PubMed", "id": "16323080", "url": "https://glygen.org/publication/PubMed/16323080" } ] }, { "annotation": "Inner ear expression patterns of Dlx3, Dlx5, and Dlx6 were examined during the first 7 days of chicken embryonic development.", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" }, { "database": "PubMed", "id": "15672396", "url": "https://glygen.org/publication/PubMed/15672396" } ] }, { "annotation": "KDM4B plays a critical role during inner ear invagination via modulating histone methylation of the direct target Dlx3.", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" }, { "database": "PubMed", "id": "26598618", "url": "https://glygen.org/publication/PubMed/26598618" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWF7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DLX3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7", "locus": { "chromosome": "27", "start_pos": 2820533, "end_pos": 2815791, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026116", "url": "https://www.ensembl.org/id/ENSGALG00010026116" } ] } } ], "crossref": [ { "id": "A0A1D5NWF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395590", "url": "https://www.ncbi.nlm.nih.gov/gene/395590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395590", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395590", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEYYPSQ", "url": "https://omabrowser.org/oma/group/HEYYPSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWF7", "url": "https://www.orthodb.org/?gene=A0A1D5NWF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A078", "url": "https://www.orthodb.org/?gene=A0A8V1A078", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12413", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12413", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWF7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A078", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A078", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A078-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A078-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSFDKKLSSILTDLSGSLSCHASSKDSPTLPESSVTDLGYYSGQHDYYPGQSYGQPVAHYPYPQFNLNAIGAGGTYSPKSDYSYSPSYRQYGHFRDQQLPAQDAVSVKEEPEPEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPAVWDSATHGGAPGRTPLPQPLPYSPSPAFLEEHSPWYHPQSLAAPHQPPAAMHHTSPGPPPNPGAVY", "length": 278, "header": "tr|A0A1D5NWF7-1|A0A1D5NWF7_CHICK Isoform 1 of Distal-less homeobox 3 OS=Gallus gallus OX=9031 GN=DLX3 PE=3 SV=2 CANONICAL=A0A1D5NWF7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWF7/entry", "sequence": { "sequence": "MSGSFDKKLSSILTDLSGSLSCHASSKDSPTLPESSVTDLGYYSGQHDYYPGQSYGQPVAHYPYPQFNLNAIGAGGTYSPKSDYSYSPSYRQYGHFRDQQLPAQDAVSVKEEPEPEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPAVWDSATHGGAPGRTPLPQPLPYSPSPAFLEEHSPWYHPQSLAAPHQPPAAMHHTSPGPPPNPGAVY", "length": 278, "header": "tr|A0A1D5NWF7-1|A0A1D5NWF7_CHICK Isoform 1 of Distal-less homeobox 3 OS=Gallus gallus OX=9031 GN=DLX3 PE=3 SV=2 CANONICAL=A0A1D5NWF7-1" }, "locus": { "chromosome": "27", "start_pos": 2819328, "end_pos": 2815897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063624.1", "url": "https://www.ensembl.org/id/ENSGALT00010063624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039275.1", "url": "https://www.ensembl.org/id/ENSGALP00010039275.1" } ] } }, { "isoform_ac": "A0A8V1A078-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A078/entry", "sequence": { "sequence": "MSGSFDKKLSSILTDLSGSLSCHASSKDSPTLPESSVTDLGYYSGQHDYYPGQSYGQPVAHYPYPQFNLNAIGAGGTYSPKSDYSYSPSYRQYGHFRDQQLPAQDAVSVKEEPEPEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVGLNAPSPIPCGGRRGWGRGRGCVPPRETGIHVGSARLSSGCPFGVGDGSVWGTPGMWGALGWVIPTCRVQGAPGAPARSRSAVLRVGDRLCPLWMLGDPCGCGALTPPNTALPLSPLSTHTDAALGVGWGLRMVPSGPPIPAPCPPFPGLGMWDVWHLAGGEGGGGALPRQVELHQEWVSPSPRFHTFLPSLGPKASLSGLPNHGHNPDLAGVTATPQPAPSPSHPAALPACGPAPAPLCRPWRALPSATFLLLPWAMKQSGPLGKGLTERVTQRDILFG", "length": 451, "header": "tr|A0A8V1A078-1|A0A1D5NWF7_CHICK Computationally mapped isoform of Distal-less homeobox 3 OS=Gallus gallus OX=9031 GN=DLX3 PE=3 SV=1 CANONICAL=A0A1D5NWF7-1" }, "locus": { "chromosome": "27", "start_pos": 2818035, "end_pos": 2815897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063622.1", "url": "https://www.ensembl.org/id/ENSGALT00010063622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039273.1", "url": "https://www.ensembl.org/id/ENSGALP00010039273.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Dlx gene expression during chick inner ear development.", "journal": "The Journal of comparative neurology", "date": "2005-02-28", "authors": "Brown Stephen T, Wang Juemei, Groves Andrew K", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ], "reference": [ { "type": "PubMed", "id": "15672396", "url": "https://glygen.org/publication/PubMed/15672396" } ] }, { "title": "Dlx3 is expressed in the ventral forebrain of chicken embryos: implications for the evolution of the Dlx gene family.", "journal": "The International journal of developmental biology", "date": "2006", "authors": "Zhu Hui, Bendall Andrew J", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ], "reference": [ { "type": "PubMed", "id": "16323080", "url": "https://glygen.org/publication/PubMed/16323080" } ] }, { "title": "Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression.", "journal": "The Journal of cell biology", "date": "2015-11-23", "authors": "Uribe Rosa A, Buzzi Ail\u00edn L, Bronner Marianne E, Strobl-Mazzulla Pablo H", "evidence": [ { "database": "RefSeq", "id": "NP_990135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990135" } ], "reference": [ { "type": "PubMed", "id": "26598618", "url": "https://glygen.org/publication/PubMed/26598618" } ] } ], "pathway": [ { "id": "gga:395590", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395590", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADD0-1", "protein_name": "Distal-less homeobox 3", "gene_name": "Dlx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGGSYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPTRNPLPPPLPYSASPNYLDDPTNSWYHTQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY", "length": 287 }, "evidence": [ { "id": "A0A1D5NWF7", "url": "https://omabrowser.org/oma/group/A0A1D5NWF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RSH8-1", "protein_name": "Distal-less homeobox 3", "gene_name": "DLX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY", "length": 287 }, "evidence": [ { "id": "A0A1D5NWF7", "url": "https://omabrowser.org/oma/group/A0A1D5NWF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HJQ7-1", "protein_name": "Homeobox protein DLX-3", "gene_name": "Dlx3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNINGLAGTGAYSPKSEYTYGGSYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPTRNQLPPPLPYSASPNYLEDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY", "length": 287 }, "evidence": [ { "id": "A0A1D5NWF7", "url": "https://omabrowser.org/oma/group/A0A1D5NWF7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60479-1", "protein_name": "Homeobox protein DLX-3", "gene_name": "DLX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY", "length": 287 }, "evidence": [ { "id": "A0A1D5NWF7", "url": "https://omabrowser.org/oma/group/A0A1D5NWF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64205-1", "protein_name": "Homeobox protein DLX-3", "gene_name": "Dlx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESTVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGGSYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARNPLPPPLPYSASPNYLDDPTNSWYHTQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY", "length": 287 }, "evidence": [ { "id": "A0A1D5NWF7", "url": 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"enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ] }, { "name": "DCAKD", "type": "synonym", "evidence": [ { "id": "XP_004948554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948554" } ] } ], "protein_names": [ { "name": "Dephospho-CoA kinase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1/entry#names_and_taxonomy" } ] }, { "name": "dephospho-CoA kinase domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948554" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948554" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCAKD", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1", "locus": { "chromosome": "27", "start_pos": 953229, "end_pos": 957598, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026796", "url": "https://www.ensembl.org/id/ENSGALG00010026796" } ] } } ], "crossref": [ { "id": "A0A1D5P2N1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P2N1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000870", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000870", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419967", "url": "https://www.ncbi.nlm.nih.gov/gene/419967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419967", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQMDIEQ", "url": "https://omabrowser.org/oma/group/CQMDIEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2N1", "url": "https://www.orthodb.org/?gene=A0A1D5P2N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADV9", "url": "https://www.orthodb.org/?gene=A0A8V1ADV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196783", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196783", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004948554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLVGLSGGIASGKSTVVAVLRELGCAVIDADVIAREVVQPRLKAYQQIVRYFGPEILLESGEINREALGSIIFSQPEKRRLLNAITHPEIQKEMLKQVLKYFVLGYRYVILDIPLLFETKRLTKFMKHTILVYCDPQTQLARLRKRSGLSQAEAEARIASQLPLDEKRRMATHVIDNSGDRESTRQQVLRLHARLEGSLDFLWARLAVGTAVAALGGLLYILLQHFIS", "length": 229, "header": "tr|A0A1D5P2N1-1|A0A1D5P2N1_CHICK Isoform 1 of Dephospho-CoA kinase domain-containing protein OS=Gallus gallus OX=9031 GN=DCAKD PE=1 SV=2 CANONICAL=A0A1D5P2N1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1/entry", "sequence": { "sequence": "MFLVGLSGGIASGKSTVVAVLRELGCAVIDADVIAREVVQPRLKAYQQIVRYFGPEILLESGEINREALGSIIFSQPEKRRLLNAITHPEIQKEMLKQVLKYFVLGYRYVILDIPLLFETKRLTKFMKHTILVYCDPQTQLARLRKRSGLSQAEAEARIASQLPLDEKRRMATHVIDNSGDRESTRQQVLRLHARLEGSLDFLWARLAVGTAVAALGGLLYILLQHFIS", "length": 229, "header": "tr|A0A1D5P2N1-1|A0A1D5P2N1_CHICK Isoform 1 of Dephospho-CoA kinase domain-containing protein OS=Gallus gallus OX=9031 GN=DCAKD PE=1 SV=2 CANONICAL=A0A1D5P2N1-1" }, "locus": { "chromosome": "27", "start_pos": 957177, "end_pos": 953393, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064990.1", "url": "https://www.ensembl.org/id/ENSGALT00010064990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039679.1", "url": "https://www.ensembl.org/id/ENSGALP00010039679.1" } ] } }, { "isoform_ac": "A0A8V1ADV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADV9/entry", "sequence": { "sequence": "MSESTMFLVGLSGGIASGKSTVVAVLRELGCAVIDADVIAREVVQPRLKAYQQIVRYFGPEILLESGEINREALGSIIFSQPEKRRLLNAITHPEIQKEMLKQVLKYFVLGYRYVILDIPLLFETKRLTKFMKHTILVYCDPQTQLARLRKRSGLSQAEAEARIASQLPLDEKRRMATHVIDNSGDRESTRQQVLRLHARLEGSLDFLWARLAVGTAVAALGGLLYILLQHFIS", "length": 234, "header": "tr|A0A8V1ADV9-1|A0A1D5P2N1_CHICK Computationally mapped isoform of Dephospho-CoA kinase domain-containing protein OS=Gallus gallus OX=9031 GN=DCAKD PE=1 SV=1 CANONICAL=A0A1D5P2N1-1" }, "locus": { "chromosome": "27", "start_pos": 957574, "end_pos": 953393, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064992.1", "url": "https://www.ensembl.org/id/ENSGALT00010064992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039680.1", "url": "https://www.ensembl.org/id/ENSGALP00010039680.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419967", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419967", "resource": "KEGG Pathway" }, { "id": "R-GGA-196783", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196783", "resource": "Reactome", "description": "Coenzyme A biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RR05-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "DCAKD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFLVGLTGGIASGKSSVLQVLQQLGCAVIDVDVIARHVVQPGYPAHRRIVEAFGTEVLLENGDIDRKALGDLIFNQPDRRHLLNAITHPEICREMTKETFKYFLRGYRYVILDVPLLFETKKLLKYMKHTVVVYCDRDTQLARLMQRNNLKQEDAEARIKAQLPLEDKARMARHVLDNSGEWSVTKRQVVLLHAELERSLEYLPLRLGVLAGLAGIVSLLYLLTHYLLASL", "length": 231 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HLM0-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "Dcakd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVIARHVVQPGYPAHRRIVQAFGTEVLLENGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRNSLKREDAEARVNAQLPLKDKARMANHVLDNSGEWSLTRRQVILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSP", "length": 231 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q03941-1", "protein_name": "Dephospho-CoA kinase CAB5", "gene_name": "CAB5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLVVGLTGGIACGKSTVSRRLRDKYKLPIVDADKIARQVVEPGQNAYDQIVLYFKDKIPNLLLEDGHLNREALGKWVFSHKEDLQALNGITHPAIRYAMFKEIGYYYLKGYRMCVLDVPLLFEGNLDSICGVTVSVICTQELQLERLMTRNPELSEEDAKNRLNSQMSTEERMARSDYILQNNSTLVDLYEQIESVVKKIQPSKLRTVLEYFPPFGAVSASSIVMSRLLMKKLQNKKSSAV", "length": 241 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0P4C4-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "dcakd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLVGLTGGIASGKSTVSSQLKELGCPVIDADVVARKVVEPQTAAYRLIVRHFGQEVLSENGEIDRKKLGQIIFSSPEKRRLLNSITHPEIHKEMLKQILLYFIKGYRYVILNVPLLFETRRLTRFLTHTVVVYCDPATQLSRLMQRDALSQTEAEQRISAQMPLKEKRGLANHVIENSGSREDTHRQVLRLHSKLDDCMQFLIIRAVAVAALTGLGGLFIYTVKIITS", "length": 229 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3ZBS0-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "DCAKD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDIIARHIVQPGYPAHRRIVEAFGTEVLLENGDIDRKVLGDLIFNQPDRRHLLNSITHPEICKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRNNLSREDAEARIKAQLPLKDKARMARHVLDNSGEWSVTKRQVVLLHAELEHSLEYLPLRLGVLTGLAGIVGLLYLLTHYLLPSP", "length": 231 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AY55-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "Dcakd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVIARHIVQPGCPAHRRIVEAFGTEVLLENGDINRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRNNLNREDAEARINSQLPLKDKARMANHVLDNSGEWSLTRRQVILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSPQLGNPGSKP", "length": 240 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHC4-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "Dcakd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVIARHVVQPGYPAHRRIVEAFGTEVLLENGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRNNLNREDAEARINAQLPLKDKARMANHVLDNSGEWSLTRRQAILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSP", "length": 231 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVC6-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "DCAKD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEVLLENGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRNSLNRKDAEARINAQLPLTDKARMARHVLDNSGEWSVTKRQVILLHTELERSLEYLPLRFGVLTGLAAIASLLYLLTHYLLPYA", "length": 231 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VI57-1", "protein_name": "Dephospho-CoA kinase domain-containing protein", "gene_name": "Dpck", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIVAVTGGIATGKSTISKVFERQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEVLLPSKEINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPLLFETGVLMDFIHKIVCVTCDSDKQLERLIARNELSESEARHRVDSQMPLDKKCEKSHFVIDNNGSVEEAESSAMSIYNLMRDSKQHWLNRISFLGLFLIVGFTIYMLLKVFNRLPESWQM", "length": 236 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZQH0-1", "protein_name": "Dephospho-CoA kinase", "gene_name": "COAE", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRIVGLTGGIASGKSTVSNLFKASGIPVVDADVVARDVLKKGSGGWKRVVAAFGEEILLPSGEVDRPKLGQIVFSSDSKRQLLNKLMAPYISSGIFWEILKQWASGAKVIVVDIPLLFEVKMDKWTKPIVVVWVSQETQLKRLMERDGLSEEDARNRVMAQMPLDSKRSKADVVIDNNGSLDDLHQQFEKVLIEIRRPLTWIEFWRSRQGAFSVLGSVILGLSVCKQLKIGS", "length": 232 }, "evidence": [ { "id": "A0A1D5P2N1", "url": "https://omabrowser.org/oma/group/A0A1D5P2N1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dephospho-CoA kinase activity", "id": "GO:0004140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004140", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2N1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUB1-1", "uniprot_ac": "A0A1D5NUB1", "uniprot_id": "A0A1D5NUB1_CHICK", "mass": { "chemical_mass": 35343.0, "monoisotopic_mass": 35343.0 }, "refseq": { "ac": "NP_001186430", "name": "annexin A13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186430" }, "gene_names": [ { "name": "ANXA13", "type": "recommended", "evidence": [ { "id": "A0A1D5NUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ] }, { "name": "ANXA13", "type": "synonym", "evidence": [ { "id": "NP_001186430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186430" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A1D5NUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1/entry#names_and_taxonomy" } ] }, { "name": "annexin A13", "type": "synonym", "evidence": [ { "id": "NP_001186430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186430" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934954.1, BX934872.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992639 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On or before Dec 9, 2010 this sequence version replaced XP_418449.1, XP_001232708.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186430" } ] }, { "annotation": "Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XZA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZA6#function" }, { "database": "UniProtKB", "id": "ARBA00056704", "url": "https://www.uniprot.org/uniprotkb/ARBA00056704#function" }, { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1#function" }, { "database": "UniProtKB", "id": "A0A8V0XT19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANXA13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1", "locus": { "chromosome": "2", "start_pos": 137121593, "end_pos": 137146227, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008286", "url": "https://www.ensembl.org/id/ENSGALG00010008286" } ] } } ], "crossref": [ { "id": "A0A1D5NUB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036418", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420342", "url": "https://www.ncbi.nlm.nih.gov/gene/420342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420342", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLIGKDM", "url": "https://omabrowser.org/oma/group/LLIGKDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUB1", "url": "https://www.orthodb.org/?gene=A0A1D5NUB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5X1", "url": "https://www.orthodb.org/?gene=A0A3Q2U5X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XT19", "url": "https://www.orthodb.org/?gene=A0A8V0XT19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXC8", "url": "https://www.orthodb.org/?gene=A0A8V0XXC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZA6", "url": "https://www.orthodb.org/?gene=A0A8V0XZA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5X1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGSHSTDKRRHHGFDAERDAKKLHSACKGAGTDEKKIIEVLSSRTSEQRQQIKQKYKALYGKDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 317, "header": "tr|A0A1D5NUB1-1|A0A1D5NUB1_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1/entry", "sequence": { "sequence": "MGGSHSTDKRRHHGFDAERDAKKLHSACKGAGTDEKKIIEVLSSRTSEQRQQIKQKYKALYGKDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 317, "header": "tr|A0A1D5NUB1-1|A0A1D5NUB1_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "locus": { "chromosome": "2", "start_pos": 137146125, "end_pos": 137122950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019814.1", "url": "https://www.ensembl.org/id/ENSGALT00010019814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011362.1", "url": "https://www.ensembl.org/id/ENSGALP00010011362.1" } ] } }, { "isoform_ac": "A0A3Q2U5X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5X1/entry", "sequence": { "sequence": "MRNAQCPWDPQIHGGAEVQQRKDSQAAGTDEKKIIEVLSSRTSEQRQQIKQKYKALYGKDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 313, "header": "tr|A0A3Q2U5X1-1|A0A3Q2U5X1_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "locus": { "chromosome": "2", "start_pos": 137133354, "end_pos": 137122950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019809.1", "url": "https://www.ensembl.org/id/ENSGALT00010019809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011357.1", "url": "https://www.ensembl.org/id/ENSGALP00010011357.1" } ] } }, { "isoform_ac": "A0A8V0XT19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT19/entry", "sequence": { "sequence": "MVRELEGKNSTDKRRHHGFDAERDAKKLHSACKGAGTDEKKIIEVLSSRTSEQRQQIKQKYKALYGKDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 321, "header": "tr|A0A8V0XT19-1|A0A1D5NUB1_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "locus": { "chromosome": "2", "start_pos": 137143864, "end_pos": 137122950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019810.1", "url": "https://www.ensembl.org/id/ENSGALT00010019810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011358.1", "url": "https://www.ensembl.org/id/ENSGALP00010011358.1" } ] } }, { "isoform_ac": "A0A8V0XXC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC8/entry", "sequence": { "sequence": "MELICGWATAHFRTIDVELAFFTVVLKLSDTSWTAGNDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 291, "header": "tr|A0A8V0XXC8-1|A0A1D5NUB1_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "locus": { "chromosome": "2", "start_pos": 137130126, "end_pos": 137122950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019804.1", "url": "https://www.ensembl.org/id/ENSGALT00010019804.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011352.1", "url": "https://www.ensembl.org/id/ENSGALP00010011352.1" } ] } }, { "isoform_ac": "A0A8V0XZA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZA6/entry", "sequence": { "sequence": "MGGSHSKSYNLPEDKREPTVGTTSLSTDKPSTDKRRHHGFDAERDAKKLHSACKGAGTDEKKIIEVLSSRTSEQRQQIKQKYKALYGKDLEEVLKGDLSGSFEKAVLALLDLPCEYKARELHKAMKGAGTDESLLIEILCTQNNQEIINTKEAYKRLFAKDLESDVKGDTSGSLRKILVTVLEATRDENQQVNTELAEQDASDLYKAGEGRWGTEELAFNVVLAKRSYSQLRATFQAYEKMCGKDIEESIKSETSGDLEKAYLTLVSCAKDCPGYFATLLHESMKGAGTDEDTLIRILVTRAESDLPAIKGKFQEMYKKSLTEAVRSDTSGDFRKLLLAILH", "length": 342, "header": "tr|A0A8V0XZA6-1|A0A1D5NUB1_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA13 PE=3 SV=1 CANONICAL=A0A1D5NUB1-1" }, "locus": { "chromosome": "2", "start_pos": 137146125, "end_pos": 137122950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019812.1", "url": "https://www.ensembl.org/id/ENSGALT00010019812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011360.1", "url": "https://www.ensembl.org/id/ENSGALP00010011360.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420342", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1HLV4-1", "protein_name": "Annexin", "gene_name": "ANXA13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNRHAKAKSDQGFDVDRDAKKLHKACKGMGTDEAAIIEILSSRTSNERQQIKQKYKATYGKDLEEVLKSELSGNFEKTALALLDRPCEYAARQLRKAMKGLGTDESVLIEILCTRTNKEIIAIKEAYQKLFDRSLESDVKSDTSGNLKKILVSLLQANREEGDNVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAQRSHKQLRATFQAYQVLIGKDIEEAIESETSGNLKKAYLTLVRSARDLQGYFADRLYKSMKGAGTDEDTLIDIIVTRAEVDLPAIKAKFQENYQTSLSDMVRADTSGDFRKLLVALLH", "length": 316 }, "evidence": [ { "id": "A0A1D5NUB1", "url": "https://omabrowser.org/oma/group/A0A1D5NUB1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZHD1-1", "protein_name": "Annexin", "gene_name": "Anxa13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNHHAKERSHHHHHGFDADRDAKKLYKACKGMGTDEAAVIEVLSSRTSEQRQQIKQKYKEKYSKDLEEVLKSELSGNFEKAALALLDRPNEYAARQLQKAMKGLGTDEAMLIEILCTRSNKEIVDIKEAYQRLFGRSLESDVKDDTSGNLRKILVSLLQAGRDEEDTVDKELAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDMEEAIEEETSGDLKKAYLTIVRCAQDLEGYFADLLYKAMKGVGTDEETLIRIIVTRAEVDLQGIKAKFQEKYQKSLSDMVHSDTSGDFRKLLVALLH", "length": 319 }, "evidence": [ { "id": "A0A1D5NUB1", "url": "https://omabrowser.org/oma/group/A0A1D5NUB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P27216-1", "protein_name": "Annexin A13", "gene_name": "ANXA13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALLH", "length": 316 }, "evidence": [ { "id": "A0A1D5NUB1", "url": "https://omabrowser.org/oma/group/A0A1D5NUB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JG3-1", "protein_name": "Annexin A13", "gene_name": "Anxa13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNRHAKERSHHHGFDADRDAKKLYKACKGMGTDEAAIIEVLSSRTSEERQQIKQKYKEKYGKDLEEVLNSELSGNFKKTALALLDRPNEYAARQLQKAMKGVGTDEAMLIEILCTRSNKEIVAIKEAYQRLFGRSLESDVKEDTSGNLRKILVSLLQASRDEEDTVDKELAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDMEETIEEETSGDLKKAYLTIVRCAQDLEGYFADLLYKAMKGMGTDEETLIRIIVTRAEVDLQGIKAKFQEKYQKSLSDMVHSDTSGDFRKLLVALLH", "length": 317 }, "evidence": [ { "id": "A0A1D5NUB1", "url": "https://omabrowser.org/oma/group/A0A1D5NUB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "phosphatidylglycerol binding", "id": "GO:1901611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901611", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "calcium ion homeostasis", "id": "GO:0055074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055074", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "calcium channel complex", "id": "GO:0034704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034704", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YM69-1", "uniprot_ac": "A0A8V0YM69", "uniprot_id": "A0A8V0YM69_CHICK", "mass": { "chemical_mass": 73258.0, "monoisotopic_mass": 73258.0 }, "refseq": {}, "gene_names": [ { "name": "PICALML", "type": "recommended", "evidence": [ { "id": "A0A8V0YM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol-binding clathrin assembly protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM65#function" }, { "database": "UniProtKB", "id": "PIRNR016396", "url": "https://www.uniprot.org/uniprotkb/PIRNR016396#function" }, { "database": "UniProtKB", "id": "ARBA00024667", "url": "https://www.uniprot.org/uniprotkb/ARBA00024667#function" }, { "database": "UniProtKB", "id": "A0A8V0YTK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK5#function" } ] }, { "annotation": "Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly. Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8. In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors. Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69#function" }, { "database": "UniProtKB", "id": "ARBA00055144", "url": "https://www.uniprot.org/uniprotkb/ARBA00055144#function" }, { "database": "UniProtKB", "id": "A0A8V0YM73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM73#function" }, { "database": "UniProtKB", "id": "A0A8V0YTL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL4#function" }, { "database": "UniProtKB", "id": "A0A1D5P5X7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5X7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PICALML", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69", "locus": { "chromosome": "4", "start_pos": 14162203, "end_pos": 14199171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015867", "url": "https://www.ensembl.org/id/ENSGALG00010015867" } ] } } ], "crossref": [ { "id": "A0A8V0YM69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008404", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008404", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16985", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16985", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772071", "url": "https://www.ncbi.nlm.nih.gov/gene/772071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772071", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P5X7", "url": "https://www.orthodb.org/?gene=A0A1D5P5X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM65", "url": "https://www.orthodb.org/?gene=A0A8V0YM65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM69", "url": "https://www.orthodb.org/?gene=A0A8V0YM69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM73", "url": "https://www.orthodb.org/?gene=A0A8V0YM73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTK5", "url": "https://www.orthodb.org/?gene=A0A8V0YTK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTL4", "url": "https://www.orthodb.org/?gene=A0A8V0YTL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22951:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22951:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P5X7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGQSITDRITAAQHSVTGSAVAKAVCKATTHEVMGPKKKHLDYLIQCTNEMNVNIPQLADTLFERTANSSWVVVFKALITTHHLMMYGNERFIQYLASRNTLFNLNNYLDKSAMQGYDMSTFIRRYSRYLNEKALSYRLVAVDFTKMKRGIDGVMRTMNAEKLLKTLPIIQNQHDALLDFEANPNELTNGVINAAFMLLFKDSIRLFAAYNEGIINLLEKYFDMKKNQCREGLDMYKKFLGRMTKLSEFLKVAEQVGIDQGDIPDLTQVSAPSSLLEALEQHLASLEGRKTKEVSAASRASALSCAVSTLANTGMSLSRMDEKEKQQALEEEQARLQALKEQRLREISVVSNSTSTSASPSTLSGKSVNTAAAVDLFAVSAPTTNSMPNLSSDLFDLQPAFVPTVQGTAATATSAGSAWGGPFSSSNGCVESPPHLDIFDMKPVEEAVKSTAPFINASLSSRHTVELFSDDFNGHNPTYTSVYHPLPVDGFPLHSAPTSATPSAINVDFDAVFGGKSTAPQYRTADDVLQPTVPPPSQRAASANQPSGKILANDLDSSLANLVGNLGFGGTPSKKSDMQWTQPAEKKLTGGTNWQAKTSTSTTWNPAPLPTLPHMVPAPVAYPVTTPQVPVYGMVPPQIGPAPLMAPQSVIYTQPGLRPTNPFAPISGTQIQFM", "length": 675, "header": "tr|A0A8V0YM69-1|A0A8V0YM69_CHICK Isoform 1 of Phosphatidylinositol-binding clathrin assembly protein OS=Gallus gallus OX=9031 GN=PICALML PE=1 SV=1 CANONICAL=A0A8V0YM69-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5X7/entry", "sequence": { "sequence": "MSGQSITDRITAAQHSVTGSAVAKAVCKATTHEVMGPKKKHLDYLIQCTNEMNVNIPQLADTLFERTANSSWVVVFKALITTHHLMMYGNERFIQYLASRNTLFNLNNYLDKSAMQGYDMSTFIRRYSRYLNEKALSYRLVAVDFTKMKRGIDGVMRTMNAEKLLKTLPIIQNQHDALLDFEANPNELTNGVINAAFMLLFKDSIRLFAAYNEGIINLLEKYFDMKKNQCREGLDMYKKFLGRMTKLSEFLKVAEQVGIDQGDIPDLTQAPSSLLEALEQHLASLEGRKTKEVSAASRASALSCAVSTLANTGMSLSRMDEKEKQQALEEEQARLQALKEQRLREISVVSNSTSTSASPSTLSGKSVNTAAAVDLFAVSAPTTNSMPNLSSDLFDLQPAFVPTVQGTAATATSAGSAWGGFPLHSAPTSATPSAINVDFDAVFGGKSTAPQYRTADDVLQPTVPPPSQRAASANQPSGKILANDLDSSLANLVGNLGFGGTPSKKSDMQWTQPAEKKLTGGTNWQAKTSTSTTWNPAPLPTLPHMVPAPVAYPVTTPQVPVYGMQVPPQIGPAPLMAPQSVIYTQPGLRPTNPFAPISGTQIQFM", "length": 605, "header": "tr|A0A1D5P5X7-1|A0A1D5P5X7_CHICK Computationally mapped isoform of Phosphatidylinositol-binding clathrin assembly protein OS=Gallus gallus OX=9031 GN=PICALML PE=1 SV=1 CANONICAL=A0A8V0YM69-1" }, "locus": { "chromosome": "4", "start_pos": 14198933, "end_pos": 14175990, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038250.1", "url": "https://www.ensembl.org/id/ENSGALT00010038250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022079.1", "url": "https://www.ensembl.org/id/ENSGALP00010022079.1" } ] } }, { "isoform_ac": "A0A8V0YM65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM65/entry", "sequence": { "sequence": "MAAASSSGPGCGEAAAAAGGKRGPLGIPEAVFVEDVDSFMKQPGNETADVVLKKLDEQYQKYKFLELNLAQKKRRLKGQIPEIKQTLEILKHMQKKKESTNPMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLSTATRNLDSLEEDLDFLRDQFTTTEVSILLICRSDVEGNVQSY", "length": 193, "header": "tr|A0A8V0YM65-1|A0A8V0YM65_CHICK Computationally mapped isoform of Prefoldin subunit 3 OS=Gallus gallus OX=9031 GN=PICALML PE=1 SV=1 CANONICAL=A0A8V0YM69-1" }, "locus": { "chromosome": "4", "start_pos": 14170124, "end_pos": 14163562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038225.1", "url": "https://www.ensembl.org/id/ENSGALT00010038225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022062.1", "url": "https://www.ensembl.org/id/ENSGALP00010022062.1" } ] } }, { "isoform_ac": "A0A8V0YM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69/entry", "sequence": { "sequence": "MSGQSITDRITAAQHSVTGSAVAKAVCKATTHEVMGPKKKHLDYLIQCTNEMNVNIPQLADTLFERTANSSWVVVFKALITTHHLMMYGNERFIQYLASRNTLFNLNNYLDKSAMQGYDMSTFIRRYSRYLNEKALSYRLVAVDFTKMKRGIDGVMRTMNAEKLLKTLPIIQNQHDALLDFEANPNELTNGVINAAFMLLFKDSIRLFAAYNEGIINLLEKYFDMKKNQCREGLDMYKKFLGRMTKLSEFLKVAEQVGIDQGDIPDLTQVSAPSSLLEALEQHLASLEGRKTKEVSAASRASALSCAVSTLANTGMSLSRMDEKEKQQALEEEQARLQALKEQRLREISVVSNSTSTSASPSTLSGKSVNTAAAVDLFAVSAPTTNSMPNLSSDLFDLQPAFVPTVQGTAATATSAGSAWGGPFSSSNGCVESPPHLDIFDMKPVEEAVKSTAPFINASLSSRHTVELFSDDFNGHNPTYTSVYHPLPVDGFPLHSAPTSATPSAINVDFDAVFGGKSTAPQYRTADDVLQPTVPPPSQRAASANQPSGKILANDLDSSLANLVGNLGFGGTPSKKSDMQWTQPAEKKLTGGTNWQAKTSTSTTWNPAPLPTLPHMVPAPVAYPVTTPQVPVYGMVPPQIGPAPLMAPQSVIYTQPGLRPTNPFAPISGTQIQFM", "length": 675, "header": "tr|A0A8V0YM69-1|A0A8V0YM69_CHICK Isoform 1 of Phosphatidylinositol-binding clathrin assembly protein OS=Gallus gallus OX=9031 GN=PICALML PE=1 SV=1 CANONICAL=A0A8V0YM69-1" }, "locus": { "chromosome": "4", "start_pos": 14198933, "end_pos": 14175990, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038234.1", "url": "https://www.ensembl.org/id/ENSGALT00010038234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022067.1", "url": "https://www.ensembl.org/id/ENSGALP00010022067.1" } ] } }, { "isoform_ac": "A0A8V0YM73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM73/entry", "sequence": { "sequence": 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"evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 572, "start_aa": "Thr", "end_pos": 572, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr572", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:772071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772071", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM69" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": 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Classification" ] }, { "id": "A0A8V0YUT9", "url": "https://www.orthodb.org/?gene=A0A8V0YUT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11486", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11486", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PQL5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGDGSGYRQLVDPAEAAGEGVQQRPGVRLQAPLQPQQGRALPLREARPGGLQQSALLQRQEKAEPQLKGIVTRLFSQQEYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKAGLYVAMNAEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 241, "header": "tr|A0A8V0YN21-1|A0A8V0YN21_CHICK Isoform 1 of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL5/entry", "sequence": { "sequence": "MRILGLLLEKGSHMLQCLCGRRLRSSNSPEPQLKGIVTRLFSQQEYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKAGLYVAMNAEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 206, "header": "tr|A0A1D5PQL5-1|A0A1D5PQL5_CHICK Computationally mapped isoform of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=2 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13103602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034099.1", "url": "https://www.ensembl.org/id/ENSGALT00010034099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020040.1", "url": "https://www.ensembl.org/id/ENSGALP00010020040.1" } ] } }, { "isoform_ac": "A0A8V0YGN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN4/entry", "sequence": { "sequence": "MEGSPKLQSFTLKGIVTRLFSQQEYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKAGLYVAMNAEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 185, "header": "tr|A0A8V0YGN4-1|A0A8V0YN21_CHICK Computationally mapped isoform of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13153667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034081.1", "url": "https://www.ensembl.org/id/ENSGALT00010034081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020029.1", "url": "https://www.ensembl.org/id/ENSGALP00010020029.1" } ] } }, { "isoform_ac": "A0A8V0YMV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMV0/entry", "sequence": { "sequence": "MAVKLSSERSYLPSYLALLLNEEQSSALFNLIPVGLRVVAIQGVKAGLYVAMNAEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 166, "header": "tr|A0A8V0YMV0-1|A0A8V0YMV0_CHICK Computationally mapped isoform of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13161063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034096.1", "url": "https://www.ensembl.org/id/ENSGALT00010034096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020038.1", "url": "https://www.ensembl.org/id/ENSGALP00010020038.1" } ] } }, { "isoform_ac": "A0A8V0YN03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN03/entry", "sequence": { "sequence": "MKRKPGLTETVSCTAMNEDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 123, "header": "tr|A0A8V0YN03-1|A0A8V0YN21_CHICK Computationally mapped isoform of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13204677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034057.1", "url": "https://www.ensembl.org/id/ENSGALT00010034057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020016.1", "url": "https://www.ensembl.org/id/ENSGALP00010020016.1" } ] } }, { "isoform_ac": "A0A8V0YN21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21/entry", "sequence": { "sequence": "MSGDGSGYRQLVDPAEAAGEGVQQRPGVRLQAPLQPQQGRALPLREARPGGLQQSALLQRQEKAEPQLKGIVTRLFSQQEYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKAGLYVAMNAEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 241, "header": "tr|A0A8V0YN21-1|A0A8V0YN21_CHICK Isoform 1 of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13137383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034094.1", "url": "https://www.ensembl.org/id/ENSGALT00010034094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020036.1", "url": "https://www.ensembl.org/id/ENSGALP00010020036.1" } ] } }, { "isoform_ac": "A0A8V0YUT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT9/entry", "sequence": { "sequence": "DSSLKSLAQGHRVWRTRDQQKNLLSELKSQCFADKDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 140, "header": "tr|A0A8V0YUT9-1|A0A8V0YN21_CHICK Computationally mapped isoform of Fibroblast growth factor OS=Gallus gallus OX=9031 GN=FGF12 PE=3 SV=1 CANONICAL=A0A8V0YN21-1" }, "locus": { "chromosome": "9", "start_pos": 13222438, "end_pos": 13205584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034071.1", "url": "https://www.ensembl.org/id/ENSGALT00010034071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020025.1", "url": "https://www.ensembl.org/id/ENSGALP00010020025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2V0-1", "protein_name": "Fibroblast growth factor", "gene_name": "FGF12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LTGRPGTAPPPPPAVGEVYIWIFTHFVATAQTLTNLVGAGFSVLQPSQILALPPRACPVPPGRRGPALAPAERDSGGRSGAGGLGPALSSYGCSDSQLLDPAEATGEGVQQRPGVGLQAPFQSQQRRALPVREARPRGIQQSALLQRPQEAKPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 328 }, "evidence": [ { "id": "A0A8V0YN21", "url": "https://omabrowser.org/oma/group/A0A8V0YN21/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LYV6-1", "protein_name": "Fibroblast growth factor", "gene_name": "Fgf12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 243 }, "evidence": [ { "id": "A0A8V0YN21", "url": "https://omabrowser.org/oma/group/A0A8V0YN21/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P61328-1", "protein_name": "Fibroblast growth factor 12", "gene_name": "FGF12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 243 }, "evidence": [ { "id": "A0A8V0YN21", "url": "https://omabrowser.org/oma/group/A0A8V0YN21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61329-1", "protein_name": "Fibroblast growth factor 12", "gene_name": "Fgf12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST", "length": 243 }, "evidence": [ { "id": "A0A8V0YN21", "url": "https://omabrowser.org/oma/group/A0A8V0YN21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "regulation of neuronal action potential", "id": "GO:0098908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQB0-1", "uniprot_ac": "A0A8V0YQB0", "uniprot_id": "A0A8V0YQB0_CHICK", "mass": { "chemical_mass": 79059.0, "monoisotopic_mass": 79059.0 }, "refseq": {}, "gene_names": [ { "name": "RNF145", "type": "recommended", "evidence": [ { "id": "A0A8V0YQB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ] } ], "protein_names": [ { "name": "RING finger protein 145", "type": "recommended", "evidence": [ { "id": "A0A8V0YQB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF145", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0", "locus": { "chromosome": "13", "start_pos": 10275522, "end_pos": 10235014, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014931", "url": "https://www.ensembl.org/id/ENSGALG00010014931" } ] } } ], "crossref": [ { "id": "A0A8V0YQB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003691", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003691", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416239", "url": "https://www.ncbi.nlm.nih.gov/gene/416239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416239", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHSAPLH", "url": "https://omabrowser.org/oma/group/MHSAPLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RQH2", "url": "https://www.orthodb.org/?gene=A0A1L1RQH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQB0", "url": "https://www.orthodb.org/?gene=A0A8V0YQB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS05", "url": "https://www.orthodb.org/?gene=A0A8V0YS05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C258", "url": "https://www.orthodb.org/?gene=E1C258", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C258", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C258", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A1L1RQH2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RQH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C258", "url": "https://www.uniprot.org/uniprotkb/E1C258", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C258-1", "url": "https://www.uniprot.org/uniprotkb/E1C258-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRHKGWSAASSQKGKRMAAKEKLEAILNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLHNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESGYEGPMYVEPLSMNRFMTALVGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSVIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPTATKEQLEQHNDICAICYQDMKTAVITPCSHFFHAGCLKKWLYVQETCPLCHCQLKSPSQLQGLGPEPVPQPNPGAEQNVRPGDAAEPPGAEQDSGPNTGDNPSQSDGQDSLEASAETEGFQDVDKGTSPYEASQGAACAAELMAAPEGCPTRDPRVSIQL", "length": 702, "header": "tr|A0A8V0YQB0-1|A0A8V0YQB0_CHICK Isoform 1 of RING finger protein 145 OS=Gallus gallus OX=9031 GN=RNF145 PE=4 SV=1 CANONICAL=A0A8V0YQB0-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RQH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQH2/entry", "sequence": { "sequence": "MAAKEKLEAILNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLHNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESGYEGPMYVEPLSMNRFMTALVGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTR", "length": 266, "header": "tr|A0A1L1RQH2-1|A0A1L1RQH2_CHICK Computationally mapped isoform of Ring finger protein 145 OS=Gallus gallus OX=9031 GN=RNF145 PE=4 SV=1 CANONICAL=A0A8V0YQB0-1" }, "locus": { "chromosome": "13", "start_pos": 10266133, "end_pos": 10243318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035921.1", "url": "https://www.ensembl.org/id/ENSGALT00010035921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020844.1", "url": "https://www.ensembl.org/id/ENSGALP00010020844.1" } ] } }, { "isoform_ac": "A0A8V0YQB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0/entry", "sequence": { "sequence": "MPRRHKGWSAASSQKGKRMAAKEKLEAILNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLHNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESGYEGPMYVEPLSMNRFMTALVGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSVIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPTATKEQLEQHNDICAICYQDMKTAVITPCSHFFHAGCLKKWLYVQETCPLCHCQLKSPSQLQGLGPEPVPQPNPGAEQNVRPGDAAEPPGAEQDSGPNTGDNPSQSDGQDSLEASAETEGFQDVDKGTSPYEASQGAACAAELMAAPEGCPTRDPRVSIQL", "length": 702, "header": "tr|A0A8V0YQB0-1|A0A8V0YQB0_CHICK Isoform 1 of RING finger protein 145 OS=Gallus gallus OX=9031 GN=RNF145 PE=4 SV=1 CANONICAL=A0A8V0YQB0-1" }, "locus": { "chromosome": "13", "start_pos": 10274315, "end_pos": 10236483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035927.1", "url": "https://www.ensembl.org/id/ENSGALT00010035927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020848.1", "url": "https://www.ensembl.org/id/ENSGALP00010020848.1" } ] } }, { "isoform_ac": "A0A8V0YS05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS05/entry", "sequence": { "sequence": "MKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSVIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPTATKEQLEQHNDICAICYQDMKTAVITPCSHFFHAGCLKKWLYVQETCPLCHCQLKSPSQLQGLGPEPVPQPNPGAEQNVRPGDAAEPPGAEQDSGPNTGDNPSQSDGQDSLEASAETEGFQDVDKGTSPYEASQGAACAAELMAAPEGCPTRDPRVSIQL", "length": 544, "header": "tr|A0A8V0YS05-1|A0A8V0YQB0_CHICK Computationally mapped isoform of RING finger protein 145 OS=Gallus gallus OX=9031 GN=RNF145 PE=4 SV=1 CANONICAL=A0A8V0YQB0-1" }, "locus": { "chromosome": "13", "start_pos": 10274315, "end_pos": 10262961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035915.1", "url": "https://www.ensembl.org/id/ENSGALT00010035915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020839.1", "url": "https://www.ensembl.org/id/ENSGALP00010020839.1" } ] } }, { "isoform_ac": "E1C258-1", "url": "https://www.uniprot.org/uniprotkb/E1C258/entry", "sequence": { "sequence": "MAAKEKLEAILNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLHNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESGYEGPMYVEPLSMNRFMTALVGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSVIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPTATKEQLEQHNDICAICYQDMKTAVITPCSHFFHAGCLKKWLYVQETCPLCHCQLKSPSQLQGLGPEPVPQPNPGAEQNVRPGDAAEPPGAEQDSGPNTGDNPSQSDGQDSLEASAETEGFQDVDKGTSPYEASQGAACAAELMAAPEGCPTRDPRVSIQL", "length": 684, "header": "tr|E1C258-1|A0A8V0YQB0_CHICK Computationally mapped isoform of RING finger protein 145 OS=Gallus gallus OX=9031 GN=RNF145 PE=4 SV=3 CANONICAL=A0A8V0YQB0-1" }, "locus": { "chromosome": "13", "start_pos": 10274315, "end_pos": 10243318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035931.1", "url": "https://www.ensembl.org/id/ENSGALT00010035931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020850.1", "url": "https://www.ensembl.org/id/ENSGALP00010020850.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BES9-1", "protein_name": "RING finger protein 145", "gene_name": "RNF145", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLPGLGSEPVPQPPAGAEQNVPEEGTEPPSQERSEDTRVQEDSKDNEECVARRLDGQEGACDPRENPLSAKDEAHPVEGSLEEKEQE", "length": 669 }, "evidence": [ { "id": "A0A8V0YQB0", "url": "https://omabrowser.org/oma/group/A0A8V0YQB0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LYG4-1", "protein_name": "RING finger protein 145", "gene_name": "Rnf145", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLERHNDICAICYQEKQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEPAPQPPVAGAEQNIVLQEGPEPPDHETPPGPGAQEGSGDNSEYINRSSASREGDADPGDGPQIAEGEACPVASA", "length": 667 }, "evidence": [ { "id": "A0A8V0YQB0", "url": "https://omabrowser.org/oma/group/A0A8V0YQB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MGV3-1", "protein_name": "RING finger protein 145", "gene_name": "RNF145", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLPGLGADPVPQPPAGAEQHALRGGTEAPGQELPQGPRAQEGSRDKDVPQPPAGAEQHALQGGTEAPGQELPQGPGAQEGSRDKDEGIARRSDSQEGTCDPKENPPGAEDEALPVEVGLEEKQQE", "length": 707 }, "evidence": [ { "id": "A0A8V0YQB0", "url": "https://omabrowser.org/oma/group/A0A8V0YQB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SWK7-1", "protein_name": "RING finger protein 145", "gene_name": "Rnf145", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFVTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATQEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEAAPQPPAGAEQNIVLQEGPEPPDHESPPGTGTQEGSGDSSEHINRGSASQEGAADAGEGPQIPEGEVCPVESA", "length": 663 }, "evidence": [ { "id": "A0A8V0YQB0", "url": "https://omabrowser.org/oma/group/A0A8V0YQB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MT1-1", "protein_name": "RING finger protein 145", "gene_name": "RNF145", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELEFAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLPGLGTEPVLQPHAGAEQNVMFQEGTEPPGQEHTPGTRIQEGSRDNNEYIARRPDNQEGAFDPKEYPHSAKDEAHPVESA", "length": 663 }, "evidence": [ { "id": "A0A8V0YQB0", "url": "https://omabrowser.org/oma/group/A0A8V0YQB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 555, "end_pos": 593, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQB2-1", "uniprot_ac": "A0A8V0YQB2", "uniprot_id": "A0A8V0YQB2_CHICK", "mass": { "chemical_mass": 56195.0, "monoisotopic_mass": 56195.0 }, "refseq": { "ac": "XP_015140105", "name": "thymopoietin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140105" }, "gene_names": [ { "name": "TMPO", "type": "recommended", "evidence": [ { "id": "A0A8V0YQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" } ] }, { "name": "TMPO", "type": "synonym", "evidence": [ { "id": "XP_015140105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140105" } ] } ], "protein_names": [ { "name": "Thymopoietin", "type": "synonym", "evidence": [ { "id": "A0A8V0YQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2/entry#names_and_taxonomy" } ] }, { "name": "thymopoietin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140105" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMPO", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2", "locus": { "chromosome": "1", "start_pos": 46737118, "end_pos": 46714703, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014294", "url": "https://www.ensembl.org/id/ENSGALG00010014294" } ] } } ], "crossref": [ { "id": "A0A8V0YQB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011504", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011504", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12935", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12935", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417923", "url": "https://www.ncbi.nlm.nih.gov/gene/417923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TPFRMEE", "url": "https://omabrowser.org/oma/group/TPFRMEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RX46", "url": "https://www.orthodb.org/?gene=A0A1L1RX46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQB2", "url": "https://www.orthodb.org/?gene=A0A8V0YQB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQC3", "url": "https://www.orthodb.org/?gene=A0A8V0YQC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVB9", "url": "https://www.orthodb.org/?gene=A0A8V0YVB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12019:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12019:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140105", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RX46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RX46-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQTYSQDGVTETVWTSGSSKSGPLQAFSRESTRVSRRTPRKRVEATLQLPVDDAVISESTPIAETILTASNETLVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEQKETDCPHQCLFNHIGRKHSYDVLNTAMIEETEESSECIKTPKVTRQLPIIKVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 498, "header": "tr|A0A8V0YQB2-1|A0A8V0YQB2_CHICK Isoform 1 of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=1 CANONICAL=A0A8V0YQB2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RX46-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RX46/entry", "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQTYSQDGVTETVWTSGSSKSGPLQAFSRESTRVSRRTPRKRVEATLQLPVDDAVISESTPIAETILTASNETLVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEQKETDCPHQCLFNHIGRKHSYDVLNTAMIEVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 476, "header": "tr|A0A1L1RX46-1|A0A1L1RX46_CHICK Computationally mapped isoform of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=2 CANONICAL=A0A8V0YQB2-1" }, "locus": { "chromosome": "1", "start_pos": 46735329, "end_pos": 46714838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034427.1", "url": "https://www.ensembl.org/id/ENSGALT00010034427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020218.1", "url": "https://www.ensembl.org/id/ENSGALP00010020218.1" } ] } }, { "isoform_ac": "A0A8V0YNJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ5/entry", "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 374, "header": "tr|A0A8V0YNJ5-1|A0A8V0YNJ5_CHICK Computationally mapped isoform of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=1 CANONICAL=A0A8V0YQB2-1" }, "locus": { "chromosome": "1", "start_pos": 46735329, "end_pos": 46714838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034413.1", "url": "https://www.ensembl.org/id/ENSGALT00010034413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020207.1", "url": "https://www.ensembl.org/id/ENSGALP00010020207.1" } ] } }, { "isoform_ac": "A0A8V0YQB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2/entry", "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQTYSQDGVTETVWTSGSSKSGPLQAFSRESTRVSRRTPRKRVEATLQLPVDDAVISESTPIAETILTASNETLVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEQKETDCPHQCLFNHIGRKHSYDVLNTAMIEETEESSECIKTPKVTRQLPIIKVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 498, "header": "tr|A0A8V0YQB2-1|A0A8V0YQB2_CHICK Isoform 1 of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=1 CANONICAL=A0A8V0YQB2-1" }, "locus": { "chromosome": "1", "start_pos": 46735329, "end_pos": 46714838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034420.1", "url": "https://www.ensembl.org/id/ENSGALT00010034420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020213.1", "url": "https://www.ensembl.org/id/ENSGALP00010020213.1" } ] } }, { "isoform_ac": "A0A8V0YQC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC3/entry", "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQVEATLQLPVDDAVISESTPIAETILTASNETLVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 406, "header": "tr|A0A8V0YQC3-1|A0A8V0YQC3_CHICK Computationally mapped isoform of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=1 CANONICAL=A0A8V0YQB2-1" }, "locus": { "chromosome": "1", "start_pos": 46735329, "end_pos": 46714838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034432.1", "url": "https://www.ensembl.org/id/ENSGALT00010034432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020223.1", "url": "https://www.ensembl.org/id/ENSGALP00010020223.1" } ] } }, { "isoform_ac": "A0A8V0YVB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB9/entry", "sequence": { "sequence": "MPEFLADPSVLTKEKLKSELIANNVSLPGGEQRKDVYVQLYLQHLTARNPPAVAQPDFSSDEEREPTPIGARGRGAAVGRKATKKTDKLRAEEKDDLDVTELSNEDLQEQLMKYGINPGPIVATTRKLYEKKLLKLMEQGPELKTPMPLPVISSTTENTRQNGNNDSDQYSDNEEEPKTELRLEKREPLKGRMKTPVTLKQRRVVEHNQTYSQDGVTETVWTSGSSKSGPLQAFSRESTRVSRRTPRKRVEATLQLPVDDAVISESTPIAETILTASNETLVGNRVPGNFKHAAPTLSISEPSDMPRRTPKKPLMTAEETEESSECIKTPKVTRQLPIIKVPERTHTEERKVERDILKEMFPYEVSTPTGISASCRRPIKGAASRPIEHTDFKMDESFFKYAPKYSTSSDIKSEKPSTKKERSVPLWIKILLFVLVSVFLFSVYQSMETNQGNPFSKYISVFTQDSSN", "length": 468, "header": "tr|A0A8V0YVB9-1|A0A8V0YQB2_CHICK Computationally mapped isoform of Thymopoietin OS=Gallus gallus OX=9031 GN=TMPO PE=1 SV=1 CANONICAL=A0A8V0YQB2-1" }, "locus": { "chromosome": "1", "start_pos": 46735329, "end_pos": 46714838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034403.1", "url": "https://www.ensembl.org/id/ENSGALT00010034403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020201.1", "url": "https://www.ensembl.org/id/ENSGALP00010020201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZSN6-1", "protein_name": "Thymopoietin", "gene_name": "LOC100622780", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPEFLEDPSVLTKEKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPTLAAGANSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVKATKKTDKPRLEDKDDLDVTELTNEELLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSVENTRQNGSNDSDRYSDNEEGKKKEHKKVKSTRDCVPFSELPTTPSGGFFQGISFPETSTRPPLGRTERQAAKKVHTSKGDPPREPLIAATLPGREQLQKLASGESLLISSKSSHGRCLEKSSSTSSQHELAALLVSAAASPSLIKETTNTCYKDIVENIYCGEKSGIQPLCTKRSHDSDQSTLSSERKALEESERSQVISPPLAQAIRDYVNSLLVQGGIGSLPGTSNSTPPLDVENTWKRIDQSNSQETESLSPPRKLPRLSGKSAEGKDSGSSVAFQNIPESELMSSSAKTVVSHSLTTLGIDMSKQSQRDKIDAPELSFPFHESILKVIEEEWQQIDRQLPSLACKYPVSSGEAVRILSVPKVDDEILGFISEATPPANIQAASTESCEKQLDLALCRTYEAAASALQIATHTAFVVQAMQADISKAAQILSTDPSRMHQALGTLSKTYDAASFLCEAAFDGVKMAAHTMGSSTLGRRYLWLRDCKINPASKNKLVVTPFKGGTLFGREALKVIKKRGNKH", "length": 691 }, "evidence": [ { "id": "A0A8V0YQB2", "url": "https://omabrowser.org/oma/group/A0A8V0YQB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MCA8-1", "protein_name": "Thymopoietin", "gene_name": "TMPO", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEFLEDPSVLTKEKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLATSANSKGPPDFSSDEEREPTPVLGSGAAVAGRSRAAVGRKATKKTDKPRPEDKDDLDVTELSNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSVENTRQNGSNDSDRYSDNEEGKKKEHKKAKSTRDFVPFSELPTTASGGFFQAISFPEISTRPPLGRTEQQAAKKVHSSKGDLPREPLTATTLPDRDQKLASGGLFVSSKSSHDRCLEKSSSSSPQHELAAMLVSAAASPSLIKETTSTCYKDTVENTYFGEKSGIQPVCTKRSHGSDQSVVSSERKALEESEQSQVISPPLARAIRDYVNSLLVQGGGDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGVTETEWTSGSSKGGLLQALTRESTRGSRRTPRKRVETSEHFRIDGAIISESTPIAETIMASSNETLVVNRVTGNFKHAAPILPITEFSDIPRRTPKKPLTRAEVGEKTEERRVERDILKEMFPFEAATPTGISASCRRPIKGAAGRPLELSDFRMEESYSSKYIPKYVPLADVKSEKTKKGRSIPMWIKILLFVVVAGFLFLVYQAMETNQGNPFYKFLSNDSKKVN", "length": 652 }, "evidence": [ { "id": "A0A8V0YQB2", "url": "https://omabrowser.org/oma/group/A0A8V0YQB2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" }, { "id": "PS50954", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50954" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LEM", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 140, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB2" }, { "id": "PS50955", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50955" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LEM-like", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 48, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 278, "end_pos": 280 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMJ1-1", "uniprot_ac": "A0A8V0YMJ1", "uniprot_id": "A0A8V0YMJ1_CHICK", "mass": { "chemical_mass": 102366.0, "monoisotopic_mass": 102366.0 }, "refseq": {}, "gene_names": [ { "name": "OSBPL8", "type": "recommended", "evidence": [ { "id": "A0A8V0YMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. Binds oxysterol, 25-hydroxycholesterol and cholesterol.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1#function" }, { "database": "UniProtKB", "id": "ARBA00054360", "url": "https://www.uniprot.org/uniprotkb/ARBA00054360#function" }, { "database": "UniProtKB", "id": "A0A3Q3AQG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQG0#function" }, { "database": "UniProtKB", "id": "A0A8V0YK05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK05#function" }, { "database": "UniProtKB", "id": "A0A8V0YKP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP6#function" }, { "database": "UniProtKB", "id": "A0A8V0YMJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ6#function" }, { "database": "UniProtKB", "id": "A0A8V0YSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSBPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1", "locus": { "chromosome": "1", "start_pos": 38128452, "end_pos": 38210928, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013444", "url": "https://www.ensembl.org/id/ENSGALG00010013444" } ] } } ], "crossref": [ { "id": "A0A8V0YMJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010246", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010246", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417866", "url": "https://www.ncbi.nlm.nih.gov/gene/417866", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417866", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417866", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AQG0", "url": "https://www.orthodb.org/?gene=A0A3Q3AQG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK05", "url": "https://www.orthodb.org/?gene=A0A8V0YK05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP6", "url": "https://www.orthodb.org/?gene=A0A8V0YKP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YMJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YMJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSH2", "url": "https://www.orthodb.org/?gene=A0A8V0YSH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1482801", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AQG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AQG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSNENKDVFPRRRAKQLGVNTFLHHGDNRDSHGPSMVTNSDESQLLTPGKMSQRQGKEAYFTPTKELLQPSLSPATAHSHGFDKGKDEASQSKEDTAHSMSKSKSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 899, "header": "tr|A0A8V0YMJ1-1|A0A8V0YMJ1_CHICK Isoform 1 of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AQG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQG0/entry", "sequence": { "sequence": "MGHGSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 798, "header": "tr|A0A3Q3AQG0-1|A0A8V0YMJ1_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38152401, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032361.1", "url": "https://www.ensembl.org/id/ENSGALT00010032361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019135.1", "url": "https://www.ensembl.org/id/ENSGALP00010019135.1" } ] } }, { "isoform_ac": "A0A8V0YK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK05/entry", "sequence": { "sequence": "MKEEGALRRRFSSCAGISSVFSARADGRKLVRNASFGGYNELSPASPGFDKGKDEASQSKEDTAHSMSKSKSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 865, "header": "tr|A0A8V0YK05-1|A0A8V0YMJ1_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38161527, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032370.1", "url": "https://www.ensembl.org/id/ENSGALT00010032370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019142.1", "url": "https://www.ensembl.org/id/ENSGALP00010019142.1" } ] } }, { "isoform_ac": "A0A8V0YKP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP6/entry", "sequence": { "sequence": "METVLVDGELDRNSSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 808, "header": "tr|A0A8V0YKP6-1|A0A8V0YMJ1_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38182211, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032386.1", "url": "https://www.ensembl.org/id/ENSGALT00010032386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019155.1", "url": "https://www.ensembl.org/id/ENSGALP00010019155.1" } ] } }, { "isoform_ac": "A0A8V0YMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1/entry", "sequence": { "sequence": "MYSNENKDVFPRRRAKQLGVNTFLHHGDNRDSHGPSMVTNSDESQLLTPGKMSQRQGKEAYFTPTKELLQPSLSPATAHSHGFDKGKDEASQSKEDTAHSMSKSKSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 899, "header": "tr|A0A8V0YMJ1-1|A0A8V0YMJ1_CHICK Isoform 1 of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38182146, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032376.1", "url": "https://www.ensembl.org/id/ENSGALT00010032376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019146.1", "url": "https://www.ensembl.org/id/ENSGALP00010019146.1" } ] } }, { "isoform_ac": "A0A8V0YMJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ6/entry", "sequence": { "sequence": "MSQRQGKEAYFTPTKELLQPSLSPATAHSHGFDKGKDEASQSKEDTAHSMSKSKSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 840, "header": "tr|A0A8V0YMJ6-1|A0A8V0YMJ6_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38172341, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032382.1", "url": "https://www.ensembl.org/id/ENSGALT00010032382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019151.1", "url": "https://www.ensembl.org/id/ENSGALP00010019151.1" } ] } }, { "isoform_ac": "A0A8V0YSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH2/entry", "sequence": { "sequence": "MSGFDKGKDEASQSKEDTAHSMSKSKSESKLFNGSEKDISLSSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQWVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAIKGPKGEAVGSITQPLPSSYLIIRAASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSSDSAHVSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKENDHEHDESDNDGLGKSEESDSDTSERQDDSYVDPEPIDIKETTYLEQSHEELGEAGEAAQTEVVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGKIKLGKEVLAILEGHWDSEVTIRDKKTDVSETFWNPTSDIKQRRLPRYTVKFEEQDDFESEKLWQQVTKAINNKDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQDSVTGEWHYRYADTRPWDPLNDMIQFEKDGTIQTKVRHRTPMVTVPKIKRKPTGQKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLGELQSAIESIKETQEDIKRDIMALRNRVTSNSPPVDNQFLQLKHYIFILLLVLLQLIINFLFK", "length": 820, "header": "tr|A0A8V0YSH2-1|A0A8V0YMJ1_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL8 PE=1 SV=1 CANONICAL=A0A8V0YMJ1-1" }, "locus": { "chromosome": "1", "start_pos": 38156598, "end_pos": 38132058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032367.1", "url": "https://www.ensembl.org/id/ENSGALT00010032367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019139.1", "url": "https://www.ensembl.org/id/ENSGALP00010019139.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417866", "resource": "KEGG Pathway" }, { "id": "R-GGA-1482801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482801", "resource": "Reactome", "description": "Acyl chain remodelling of PS" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "positive regulation of D-glucose import", "id": "GO:0046326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "intermembrane phospholipid transfer", "id": "GO:0120010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "transporter complex", "id": "GO:1990351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ1" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 275, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNJ3-1", "uniprot_ac": "A0A8V0YNJ3", "uniprot_id": "A0A8V0YNJ3_CHICK", "mass": { "chemical_mass": 87798.0, "monoisotopic_mass": 87798.0 }, "refseq": { "ac": "XP_015153230", "name": "lethal(3)malignant brain tumor-like protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153230" }, "gene_names": [ { "name": "L3MBTL4", "type": "recommended", "evidence": [ { "id": "A0A8V0YNJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ] }, { "name": "L3MBTL4", "type": "synonym", "evidence": [ { "id": "XP_015153230", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153230" } ] } ], "protein_names": [ { "name": "L3MBTL histone methyl-lysine binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YNJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3/entry#names_and_taxonomy" } ] }, { "name": "lethal(3)malignant brain tumor-like protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015153230", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153230" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153230.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153230" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "L3MBTL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029653", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20133", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20133", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20139", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20139", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419599", "url": "https://www.ncbi.nlm.nih.gov/gene/419599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AV02", "url": "https://www.orthodb.org/?gene=A0A3Q3AV02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUY7", "url": "https://www.orthodb.org/?gene=A0A8V0YUY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVB8", "url": "https://www.orthodb.org/?gene=A0A8V0YVB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153230", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3AV02", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AV02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AV02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AV02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGAHEGRSDIPVSDVRSRPGPARSAAAPPCPQRSRARGRCRSSHACVLPAAGSLNVARVEEKRKARGGRAGLCGVPKDDVPCSDFPTCKQMDCFENGKFCAQHHRDSDTKEIPDGCRNRGNGRNLNASIGCQVNEADRPVKRLRRKRRLLLESEDDEENAYEDEEKNKSNNMKSRRNSKPIKQVVPAKKKVWNWISYLEEERMPAAPLKLFRESQSFPQGRNGFKVGMKLEGLDPEHPSRFCVLTVAEVQGYRMRLHFDGYPECYDFWVNADSSDIHPVGWCEKTSHKLLPPKGFKEGEFNWTSYLKNCKAQAAPKSLFKTLSTPVTPSGFRLGMKLEAVDKKHPSLMCVATISDMVDNRLLIHFDNWDETYDYWCESSSPYIRPVGYCQETGTPLTTPPGYKDPKAFSWEKYLVETNSQAAPARAFKLRPAHGFQVNMKLEAVDKRNPILIRVATITDRDDHRIKIHFDGWDCNYDFWVDADSPDVHPVGWCAKTGHALQVPLGAVDPVGTVGQTCPTPGCHGIGHVRGPRYGTHYTLVGCPYSDVNLNKENVLQDRLGGERPSPSSSLQKAKKLETPAQVLLRAGEPSQEDSPQSRKSAQDSEKSCQSSVQSPSEQSESNEAKDWVEEKPSENIKAKPKKLGCSHAYIKLQLVKQENNGKDLDFNLQQALHQSIFMPALDSNPSHRLHLCWEQHCRLLPEVLGLTAKHVSKWTVEEVVNFIQRLPGCKEQAAVFREEQIDGEAFLLLNQNDLVKILNIKLGPALKVYNAILMLKSAEEE", "length": 783, "header": "tr|A0A8V0YNJ3-1|A0A8V0YNJ3_CHICK Isoform 1 of L3MBTL histone methyl-lysine binding protein 4 OS=Gallus gallus OX=9031 GN=L3MBTL4 PE=4 SV=1 CANONICAL=A0A8V0YNJ3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AV02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AV02/entry", "sequence": { "sequence": "MLELITEVEAEKAEALETLSASAINASPASFAPAAINAPAAFSTALEVPKDDVPCSDFPTCKQMDCFENGKFCAQHHRDSDTKEIPDGCRNRGNGRNLNASIGCQVNEADRPVKRLRRKRRLLLESEDDEENAYEDEEKNKSNNMKSRRNSKPIKQVVPAKKKVWNWISYLEEERMPAAPLKLFRESQSFPQGRNGFKVGMKLEGLDPEHPSRFCVLTVAEVQGYRMRLHFDGYPECYDFWVNADSSDIHPVGWCEKTSHKLLPPKGFKEGEFNWTSYLKNCKAQAAPKSLFKTLSTPVTPSGFRLGMKLEAVDKKHPSLMCVATISDMVDNRLLIHFDNWDETYDYWCESSSPYIRPVGYCQETGTPLTTPPGYKDPKAFSWEKYLVETNSQAAPARAFKLRPAHGFQVNMKLEAVDKRNPILIRVATITDRDDHRIKIHFDGWDCNYDFWVDADSPDVHPVGWCAKTGHALQVPLGAVDPVGTVGQTCPTPGCHGIGHVRGPRYGTHYTLVGCPYSDVNLNKENVLQDRLGGERPSPSSSLQKAKKLETPAQVLLRAGEPSQEDSPQSRKSAQDSEKSCQSSVQSPSEQSESNEAKDWVEEKPSENIKAKPKKLGCSHAYIKLQLVKQENNGKDLDFNLQQALHQSIFMPALDSNPSHRLHLCWEQHCRLLPEVLGLTAKHVSKWTVEEVVNFIQRLPGCKEQAAVFREEQIDGEAFLLLNQNDLVKILNIKLGPALKVYNAILMLKSAEEE", "length": 754, "header": "tr|A0A3Q3AV02-1|A0A8V0YNJ3_CHICK Computationally mapped isoform of L3MBTL histone methyl-lysine binding protein 4 OS=Gallus gallus OX=9031 GN=L3MBTL4 PE=4 SV=1 CANONICAL=A0A8V0YNJ3-1" }, "locus": { "chromosome": "23", "start_pos": 3085731, "end_pos": 3056898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039080.1", "url": "https://www.ensembl.org/id/ENSGALT00010039080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022571.1", "url": "https://www.ensembl.org/id/ENSGALP00010022571.1" } ] } }, { "isoform_ac": "A0A8V0YNJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3/entry", "sequence": { "sequence": "MGGGAHEGRSDIPVSDVRSRPGPARSAAAPPCPQRSRARGRCRSSHACVLPAAGSLNVARVEEKRKARGGRAGLCGVPKDDVPCSDFPTCKQMDCFENGKFCAQHHRDSDTKEIPDGCRNRGNGRNLNASIGCQVNEADRPVKRLRRKRRLLLESEDDEENAYEDEEKNKSNNMKSRRNSKPIKQVVPAKKKVWNWISYLEEERMPAAPLKLFRESQSFPQGRNGFKVGMKLEGLDPEHPSRFCVLTVAEVQGYRMRLHFDGYPECYDFWVNADSSDIHPVGWCEKTSHKLLPPKGFKEGEFNWTSYLKNCKAQAAPKSLFKTLSTPVTPSGFRLGMKLEAVDKKHPSLMCVATISDMVDNRLLIHFDNWDETYDYWCESSSPYIRPVGYCQETGTPLTTPPGYKDPKAFSWEKYLVETNSQAAPARAFKLRPAHGFQVNMKLEAVDKRNPILIRVATITDRDDHRIKIHFDGWDCNYDFWVDADSPDVHPVGWCAKTGHALQVPLGAVDPVGTVGQTCPTPGCHGIGHVRGPRYGTHYTLVGCPYSDVNLNKENVLQDRLGGERPSPSSSLQKAKKLETPAQVLLRAGEPSQEDSPQSRKSAQDSEKSCQSSVQSPSEQSESNEAKDWVEEKPSENIKAKPKKLGCSHAYIKLQLVKQENNGKDLDFNLQQALHQSIFMPALDSNPSHRLHLCWEQHCRLLPEVLGLTAKHVSKWTVEEVVNFIQRLPGCKEQAAVFREEQIDGEAFLLLNQNDLVKILNIKLGPALKVYNAILMLKSAEEE", "length": 783, "header": "tr|A0A8V0YNJ3-1|A0A8V0YNJ3_CHICK Isoform 1 of L3MBTL histone methyl-lysine binding protein 4 OS=Gallus gallus OX=9031 GN=L3MBTL4 PE=4 SV=1 CANONICAL=A0A8V0YNJ3-1" }, "locus": { "chromosome": "23", "start_pos": 3097508, "end_pos": 3056898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039089.1", "url": "https://www.ensembl.org/id/ENSGALT00010039089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022576.1", "url": "https://www.ensembl.org/id/ENSGALP00010022576.1" } ] } }, { "isoform_ac": "A0A8V0YUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUY7/entry", "sequence": { "sequence": "MPKDDVPCSDFPTCKQMDCFENGKFCAQHHRDSDTKEIPDGCRNRGNGRNLNASIGCQVNEADRPVKRLRRKRRLLLESEDDEENAYEDEEKNKSNNMKSRRNSKPIKQVVPAKKKVWNWISYLEEERMPAAPLKLFRESQSFPQGRNGFKVGMKLEGLDPEHPSRFCVLTVAEVQGYRMRLHFDGYPECYDFWVNADSSDIHPVGWCEKTSHKLLPPKGFKEGEFNWTSYLKNCKAQAAPKSLFKTLSTPVTPSGFRLGMKLEAVDKKHPSLMCVATISDMVDNRLLIHFDNWDETYDYWCESSSPYIRPVGYCQETGTPLTTPPGYKDPKAFSWEKYLVETNSQAAPARAFKLRPAHGFQVNMKLEAVDKRNPILIRVATITDRDDHRIKIHFDGWDCNYDFWVDADSPDVHPVGWCAKTGHALQVPLGAVDPVGTVGQTCPTPGCHGIGHVRGPRYGTHYTLVGCPYSDVNLNKENVLQDRLGGERPSPSSSLQKAKKLETPAQVLLRAGEPSQEDSPQSRKSAQDSEKSCQSSVQSPSEQSESNEAKDWVEEKPSENIKAKPKKLGCSHAYIKLQLVKQENNGKDLDFNLQQALHQSIFMPALDSNPSHRLHLCWEQHCRLLPEVLGLTAKHVSKWTVEEVVNFIQRLPGCKEQAAVFREEQIDGEAFLLLNQNDLVKILNIKLGPALKVYNAILMLKSAEEE", "length": 707, "header": "tr|A0A8V0YUY7-1|A0A8V0YNJ3_CHICK Computationally mapped isoform of L3MBTL histone methyl-lysine binding protein 4 OS=Gallus gallus OX=9031 GN=L3MBTL4 PE=4 SV=1 CANONICAL=A0A8V0YNJ3-1" }, "locus": { "chromosome": "23", "start_pos": 3088956, "end_pos": 3056898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039074.1", "url": "https://www.ensembl.org/id/ENSGALT00010039074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022568.1", "url": "https://www.ensembl.org/id/ENSGALP00010022568.1" } ] } }, { "isoform_ac": "A0A8V0YVB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB8/entry", "sequence": { "sequence": "MMRKMRMRMSYEWQFGSKCDARKPVLGCSSMTEKNKSNNMKSRRNSKPIKQVVPAKKKVWNWISYLEEERMPAAPLKLFRESQSFPQGRNGFKVGMKLEGLDPEHPSRFCVLTVAEVQGYRMRLHFDGYPECYDFWVNADSSDIHPVGWCEKTSHKLLPPKGFKEGEFNWTSYLKNCKAQAAPKSLFKTLSTPVTPSGFRLGMKLEAVDKKHPSLMCVATISDMVDNRLLIHFDNWDETYDYWCESSSPYIRPVGYCQETGTPLTTPPGYKDPKAFSWEKYLVETNSQAAPARAFKLRPAHGFQVNMKLEAVDKRNPILIRVATITDRDDHRIKIHFDGWDCNYDFWVDADSPDVHPVGWCAKTGHALQVPLGAVDPVGTVGQTCPTPGCHGIGHVRGPRYGTHYTLVGCPYSDVNLNKENVLQDRLGGERPSPSSSLQKAKKLETPAQVLLRAGEPSQEDSPQSRKSAQDSEKSCQSSVQSPSEQSESNEAKDWVEEKPSENIKAKPKKLGCSHAYIKLQLVKQENNGKDLDFNLQQALHQSIFMPALDSNPSHRLHLCWEQHCRLLPEVLGLTAKHVSKWTVEEVVNFIQRLPGCKEQAAVFREEQIDGEAFLLLNQNDLVKILNIKLGPALKVYNAILMLKSAEEE", "length": 649, "header": "tr|A0A8V0YVB8-1|A0A8V0YNJ3_CHICK Computationally mapped isoform of L3MBTL histone methyl-lysine binding protein 4 OS=Gallus gallus OX=9031 GN=L3MBTL4 PE=4 SV=1 CANONICAL=A0A8V0YNJ3-1" }, "locus": { "chromosome": "23", "start_pos": 3082919, "end_pos": 3056898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039067.1", "url": "https://www.ensembl.org/id/ENSGALT00010039067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022565.1", "url": "https://www.ensembl.org/id/ENSGALP00010022565.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 329, "start_aa": "Thr", "end_pos": 329, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr329", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 521, "start_aa": "Thr", "end_pos": 521, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr521", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 294, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YNJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ3" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 716, "end_pos": 780, "start_aa": "Trp", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 329, 521 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLH5-1", "uniprot_ac": "A0A8V0YLH5", "uniprot_id": "A0A8V0YLH5_CHICK", "mass": { "chemical_mass": 99102.0, "monoisotopic_mass": 99102.0 }, "refseq": {}, "gene_names": [ { "name": "KIF20A", "type": "recommended", "evidence": [ { "id": "A0A8V0YLH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ] } ], "protein_names": [ { "name": "Kinesin-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YLH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y8C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C8#function" }, { "database": "UniProtKB", "id": "ARBA00055972", "url": "https://www.uniprot.org/uniprotkb/ARBA00055972#function" }, { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5#function" }, { "database": "UniProtKB", "id": "A0A8V0YLI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIF20A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5", "locus": { "chromosome": "13", "start_pos": 9667803, "end_pos": 9677819, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012186", "url": "https://www.ensembl.org/id/ENSGALG00010012186" } ] } } ], "crossref": [ { "id": "A0A8V0YLH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416220", "url": "https://www.ncbi.nlm.nih.gov/gene/416220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416220", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRHPQKA", "url": "https://omabrowser.org/oma/group/NRHPQKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8C8", "url": "https://www.orthodb.org/?gene=A0A8V0Y8C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH5", "url": "https://www.orthodb.org/?gene=A0A8V0YLH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI5", "url": "https://www.orthodb.org/?gene=A0A8V0YLI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47970:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47970:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68884", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68884", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQGLVSPGLFSDDDGAAASPVLESTATGFGADVRKDLLSEFSAISPNLEGSQQAIAEDVNGKLKVYVRVRPLKPTELEKGEDQGCVCIENSETLLLKAPKDSFTMRSTERGVGQAAHRFSFTQIFGPDVGQKLFFDETMKQVVKDVLNGQNWLVYTYGNTNSGKTHTIQGSIKDGGILPRSLAVIFNSVGDRLYQAMDLKPSLCNEVIWLDSKQVRQEETKKQSMLRGGVWEEELLTPLKRSYSAESQLQATNSGSFDSGVAGLSSSSQFTSHSDISQAEELGPRWADLDRISLSTTGDVQFSIWVSFFEIYNELIYDLLEPALPGQNRKRQTLRLCEDQTGNPYVKDLNWINVRDADEAWKLLKLGRKNQSFASTHMNQNSSRSHSIFSIRILHLQGGGSEIVPKISELSLCDLAGSERCKDQKSGDRMKEANNINTSLHTLGRCITALRQKQQSKLKQIVVPFRDSKLTRVFQGFFTGRGRSCMIVNINQCASTYDETLYVAKFSAIASQLVQAPPTKLGLPSIQSIIKEHSRRTSQGSEATEKEEVKTEDSEDEADVSVYEREDLLRVVEAARELLVQERQEKLQLEIRLRTEICNEMLESMQQKEQWWSQHIDAQKELLEELYEDKLNNLKESLTDYYQEEIQRDEKIEELQAALQEAKQKLDAKQRDSEQGLRRSKRVAASCALQQELTDTKAKLEQCQMELNTTSSELRKYQRLLEPPPSAKPITVDVDKKLEDGQKNVRLLRSELQKLGESLQSAERACCHSTGAGKLREALCTCDDILTRQDQTLAELQNNMMLVKLDLRKKAACIAEQYHTVHKLQAPPMSTLKKRFCANRENLQPNQPPGKKPFLHNLLTRSAPRPAATRGWQLRSVAL", "length": 880, "header": "tr|A0A8V0YLH5-1|A0A8V0YLH5_CHICK Isoform 1 of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF20A PE=3 SV=1 CANONICAL=A0A8V0YLH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C8/entry", "sequence": { "sequence": "MLVGSGRARRAAVLTSPCAAFSSGAVWDAMEQGLVSPGLFSDDDGAAASPVLESTATGFGADVRKDLLSEFSAISPNLEGSQQAIAEDVNGKLKVYVRVRPLKPTELEKGEDQGCVCIENSETLLLKAPKDSFTMRSTERGVGQAAHRFSFTQIFGPDVGQKLFFDETMKQVVKDVLNGQNWLVYTYGNTNSGKTHTIQGSIKDGGILPRSLAVIFNSVGDRLYQAMDLKPSLCNEVIWLDSKQVRQEETKKQSMLRGGVWEEELLTPLKRSYSAESQLQATNSGSFDSGVAGLSSSSQFTSHSDISQAEELGPRWADLDRISLSTTGDVQFSIWVSFFEIYNELIYDLLEPALPGQNRKRQTLRLCEDQTGNPYVKDLNWINVRDADEAWKLLKLGRKNQSFASTHMNQNSSRSHSIFSIRILHLQGGGSEIVPKISELSLCDLAGSERCKDQKSGDRMKEANNINTSLHTLGRCITALRQKQQSKLKQIVVPFRDSKLTRVFQGFFTGRGRSCMIVNINQCASTYDETLYVAKFSAIASQLVQAPPTKLGLPSIQSIIKEHSRRTSQGSEATEKEEVKTEDSEDEADVSVYEREDLLRVVEAARELLVQERQEKLQLEIRLRTEICNEMLESMQQKEQWWSQHIDAQKELLEELYEDKLNNLKESLTDYYQEEIQERDEKIEELQAALQEAKQKLDAKQRDSEQGLRRSKRVAASCALQQELTDTKAKLEQCQMELNTTSSELRKYQRLLEPPPSAKPITVDVDKKLEDGQKNVRLLRSELQKLGESLQSAERACCHSTGAGKLREALCTCDDILTRQDQTLAELQNNMMLVKLDLRKKAACIAEQYHTVHKLQAPPMSTLKKRFCANRENLQPNQPPGKKPFLHNLLTRSAPRPAATRGWQLRSVAL", "length": 910, "header": "tr|A0A8V0Y8C8-1|A0A8V0YLH5_CHICK Computationally mapped isoform of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF20A PE=3 SV=1 CANONICAL=A0A8V0YLH5-1" }, "locus": { "chromosome": "13", "start_pos": 9677625, "end_pos": 9669596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029227.1", "url": "https://www.ensembl.org/id/ENSGALT00010029227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016952.1", "url": "https://www.ensembl.org/id/ENSGALP00010016952.1" } ] } }, { "isoform_ac": "A0A8V0YLH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5/entry", "sequence": { "sequence": "MEQGLVSPGLFSDDDGAAASPVLESTATGFGADVRKDLLSEFSAISPNLEGSQQAIAEDVNGKLKVYVRVRPLKPTELEKGEDQGCVCIENSETLLLKAPKDSFTMRSTERGVGQAAHRFSFTQIFGPDVGQKLFFDETMKQVVKDVLNGQNWLVYTYGNTNSGKTHTIQGSIKDGGILPRSLAVIFNSVGDRLYQAMDLKPSLCNEVIWLDSKQVRQEETKKQSMLRGGVWEEELLTPLKRSYSAESQLQATNSGSFDSGVAGLSSSSQFTSHSDISQAEELGPRWADLDRISLSTTGDVQFSIWVSFFEIYNELIYDLLEPALPGQNRKRQTLRLCEDQTGNPYVKDLNWINVRDADEAWKLLKLGRKNQSFASTHMNQNSSRSHSIFSIRILHLQGGGSEIVPKISELSLCDLAGSERCKDQKSGDRMKEANNINTSLHTLGRCITALRQKQQSKLKQIVVPFRDSKLTRVFQGFFTGRGRSCMIVNINQCASTYDETLYVAKFSAIASQLVQAPPTKLGLPSIQSIIKEHSRRTSQGSEATEKEEVKTEDSEDEADVSVYEREDLLRVVEAARELLVQERQEKLQLEIRLRTEICNEMLESMQQKEQWWSQHIDAQKELLEELYEDKLNNLKESLTDYYQEEIQRDEKIEELQAALQEAKQKLDAKQRDSEQGLRRSKRVAASCALQQELTDTKAKLEQCQMELNTTSSELRKYQRLLEPPPSAKPITVDVDKKLEDGQKNVRLLRSELQKLGESLQSAERACCHSTGAGKLREALCTCDDILTRQDQTLAELQNNMMLVKLDLRKKAACIAEQYHTVHKLQAPPMSTLKKRFCANRENLQPNQPPGKKPFLHNLLTRSAPRPAATRGWQLRSVAL", "length": 880, "header": "tr|A0A8V0YLH5-1|A0A8V0YLH5_CHICK Isoform 1 of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF20A PE=3 SV=1 CANONICAL=A0A8V0YLH5-1" }, "locus": { "chromosome": "13", "start_pos": 9677538, "end_pos": 9669596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029223.1", "url": "https://www.ensembl.org/id/ENSGALT00010029223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016948.1", "url": "https://www.ensembl.org/id/ENSGALP00010016948.1" } ] } }, { "isoform_ac": "A0A8V0YLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI5/entry", "sequence": { "sequence": "MEQGLVSPGLFSDDDGAAASPVLESTATGFGADVRKDLLSEFSAISPNLEGSQQAIAEDVNGKLKVYVRVRPLKPTELEKGEDQGCVCIENSETLLLKAPKDSFTMRSTERGVGQAAHRFSFTQIFGPDVGQKLFFDETMKQVVKDVLNGQNWLVYTYGNTNSGKTHTIQGSIKDGGILPRSLAVIFNSVGDRLYQAMDLKPSLCNEVIWLDSKQVRQEETKKQSMLRGGVWEEELLTPLKRSYSAESQLQATNSGSFDSGVAGLSSSSQFTSHSDISQAEELGPRWADLDRISLSTTGDVQFSIWVSFFEIYNELIYDLLEPALPGQNRKRQTLRLCEDQTGNPYVKDLNWINVRDADEAWKLLKLGRKNQSFASTHMNQNSSRSHSIFSIRILHLQGGGSEIVPKISELSLCDLAGSERCKDQKSGDRMKEANNINTSLHTLGRCITALRQKQQSKLKQIVVPFRDSKLTRVFQGFFTGRGRSCMIVNINQCASTYDETLYVAKFSAIASQLVQAPPTKLGLPSIQSIIKEHSRRTSQGSEATEKEEVKTEDSEDEADVSVYEREDLLRVVEAARELLVQERQEKLQLEIRLRTEICNEMLESMQQKEQWWSQHIDAQKELLEELYEDKLNNLKESLTDYYQEEIQERDEKIEELQAALQEAKQKLDAKQRDSEQGLRRSKRVAASCALQQELTDTKAKLEQCQMELNTTSSELRKYQRLLEPPPSAKPITVDVDKKLEDGQKNVRLLRSELQKLGESLQSAERACCHSTGAGKLREALCTCDDILTRQDQTLAELQNNMMLVKLDLRKKAACIAEQYHTVHKLQAPPMSTLKKRFCANRENLQPNQPPGKKPFLHNLLTRSAPRPAATRGWQLRSVAL", "length": 881, "header": "tr|A0A8V0YLI5-1|A0A8V0YLI5_CHICK Computationally mapped isoform of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF20A PE=3 SV=1 CANONICAL=A0A8V0YLH5-1" }, "locus": { "chromosome": "13", "start_pos": 9677538, "end_pos": 9669596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029233.1", "url": "https://www.ensembl.org/id/ENSGALT00010029233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016958.1", "url": "https://www.ensembl.org/id/ENSGALP00010016958.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416220", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-68884", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68884", "resource": "Reactome", "description": "Mitotic Telophase/Cytokinesis" }, { "id": "R-GGA-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V2Q7-1", "protein_name": "Kinesin-like protein", "gene_name": "KIF20A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQGILSPPAGLLSDEEVVVSPMFESTAADLGSVVRKELLSDCSVISTSLDDKQQVPSEGSMEKVKVYLRVRPFLPSELERQEDQGCVRIENMETLALQAPKDSFAQKSNERGIGQATHRFTFSQIFGPEVGQAPFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLTLIFNSLQGQLHPTPDLKPLLSNEVMWLDSKQIRQEELKKLALLSGGLQEEDLSTSLKKSVYIESRMGTSTSFDSGIAGLSSTSQFTSSSQLDETSHRWAQPDTAPVSVPADIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWINVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGDGDIIPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPLQLGFPSLHSFIKEHSLRASPSLETGAKTDPSLDDDIENEVDISTYGKEELLQVVEAMKALLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLTILKESLTSFYQEELQERDEKIEELEALLQEAREQSVAHQQPGSELSLRRSQRLAASASTQQLQEIKAKLEQCKAELNSTTEELRKYQKMLEPPPSAKPFIVDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALATCDDILIKQDQTLAELQNNMMLVKLDLRKKAACIAEQYHTVLKLQGQASTKKRLGANQENQLPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY", "length": 890 }, "evidence": [ { "id": "A0A8V0YLH5", "url": "https://omabrowser.org/oma/group/A0A8V0YLH5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QDF0-1", "protein_name": "Kinesin-like protein", "gene_name": "kif20a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALASPCGILSDEEECGAVFESTAADVVGLMRSQRFVSPLPEISVITPAADSLTPTKELVQIKSDISRRGSTDDGSDKLKVFLRIRPLTEAEKDRGEEQGCVNVQSEDNLLLKAPKDSRNMKSAERGVAQSVHKFTFTKIFGPQTSQQEVYDHTIREMVRDVLRGENRLLYTYGVTNSGKTYTIQGAGAEAGLLPRALVSVFLKLSGRLYTAMDLKPVLSQEVRKLDVGEVRAEEMRRDALLKEDESNQSRLRAGLSWDSGISGLSATSHIATQLEDSDGVCLEANGLCLSGGEDLEEGVQFSVWVSFYEIYNEFLYDLLDAPPSLQSRKRVTLRLSDDKHGNPYVKDLTWIQVHSAEEAWKVLKVGQRNQSFASTHLNHNSSRSHSIFTIRVLHVKPQLGQVTRISELSVCDLAGSERCKAQQNGERMKEANNINTSLLTLGRCITALRHNQTNKSRPPVVVPFRDSKLTRVLQSFFCGHGRSCMVVNINPCASTYDETLQALKFSAIATQLVHGPCSKTRVAYILSLLREQPTHPNDTTLLEEDEEESDEEGDITMFDPEALLKAIDVLKREVLRQRQEKEELEAKVREEVCTEMMEVISRMQDDFSETLESERDLMEKRCENKINNLKSSLKKYYSQELEERDDEIRELTAALKEKEAGNTAPAAIFPPLNDDGGLRRSQRLASTHKRDADHESIELFRCKAELENCRAELDLKQTELRLKTLELKRFQDNLPSMGVTGTLTTTAERKLEEGQRNLKQLRMELQLLGIKLQSGERACCRNTDGEKLRHALSSADSKLAKQDQMLVELHTSLQLVKAELRKKDELLTRFQNTQQAQSHQPPTASGSCKKRGCGVAVALAENQPPEKRPFFRSLFPSRTPSKTPSRPTRQQNEVTTPYSRVLRSRQPSPPTTPVMLRVKY", "length": 921 }, "evidence": [ { "id": "A0A8V0YLH5", "url": "https://omabrowser.org/oma/group/A0A8V0YLH5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95235-1", "protein_name": "Kinesin-like protein KIF20A", "gene_name": "KIF20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY", "length": 890 }, "evidence": [ { "id": "A0A8V0YLH5", "url": "https://omabrowser.org/oma/group/A0A8V0YLH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97329-1", "protein_name": "Kinesin-like protein KIF20A", "gene_name": "Kif20a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHRILSPPAGLLSDEDVVDSPILESTAADLRSVVRKDLLSDCSVISASLEDKQALLEDTSEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFALKSNERGVGQATHKFTFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTSKDAGILPQSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLIGGLQEEELSTSVKKRVHTESRIGASNSFDSGVAGLSSTSQFTSSSQLDETSQLWAQPDTVPVSVPADIRFSVWISFFEIYNELLYDLLEPPSHQHKRQTLRLCEDQNGNPYVKDLNWIHVRDVEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKHQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLIPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHAAKFSALASQLVHAPPVHLGIPSLHSFIKKHSPQVGPGLEKEDKADSDLEDSPEDEADVSVYGKEELLQVVEAMKALLLKERQEKLQLEIQLREEICNEMVEQMQQREQWCSERLDNQKELMEELYEEKLKILKESLTTFYQEQIQERDEKIEELETLLQEAKQQPAAQQSGGLSLLRRSQRLAASASTQQFQEVKAELEQCKTELSSTTAELHKYQQVLKPPPPAKPFTIDVDKKLEEGQKNIRLLRTELQKLGQSLQSAERACCHSTGAGKLRQALTNCDDILIKQNQTLAELQNNMVLVKLDLQKKAACIAEQYHTVLKLQGQASAKKRLGANQENQQPNHQPPGKKPFLRNLLPRTPTCQSSTDSSPYARILRSRHSPLLKSPFGKKY", "length": 887 }, "evidence": [ { "id": "A0A8V0YLH5", "url": "https://omabrowser.org/oma/group/A0A8V0YLH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q29RT6-1", "protein_name": "Kinesin-like protein KIF20A", "gene_name": "KIF20A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQGILSPPAGLLSDEEVVVSPMFESTAADLGSVIRKDLLSDCSVISTSLEDKQVPSEDGTEKVKVYLRVRPLLPSELERQEDQGCVCIENMETLALQAPKDSFAQKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTIKDGGILPRSLALIFNSLQGQLHPTPNLKPLFSNEVMWLDSKQIRQEELKKLALLNGGLQEEELSTSLKKSVYIDSRMGTSTSFDSGIAGLSSSSQFPSSSQLDEMSHRWAQPDTVPVSVPADLRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIIPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPVQLGFPSIHSFLKEHSLRASPSLETGAKTDPGLGDDIENEVDISTYGKEELLQVVEAMKALLLKERQEKLRLEVQLRDEICNEMVEQMQQREQWCSEHLDTQKELLEELYEDKLTILKESLTSFYQEELQERDEKIKELEALLQEARQQQVAHQPSGSELSLRRSQRLTSVSTQQFHEIKAKLEQCKAELNSTTEELQKYQKMLEPPPSAKPFIVDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHNTGAGKLRQALATCDDILIKQDQTLAELQNNMTLVKLDLRKKAACIAEQYHTVLKLQGQASTKKRLGANQENQQPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY", "length": 888 }, "evidence": [ { "id": "A0A8V0YLH5", "url": "https://omabrowser.org/oma/group/A0A8V0YLH5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH5" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 514, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 709, "end_pos": 711 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YM96-1", "uniprot_ac": "A0A8V0YM96", "uniprot_id": "A0A8V0YM96_CHICK", "mass": { "chemical_mass": 112796.0, "monoisotopic_mass": 112796.0 }, "refseq": {}, "gene_names": [ { "name": "STK10", "type": "recommended", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": 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"id": "cd06644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416204", "url": "https://www.ncbi.nlm.nih.gov/gene/416204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416204", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHMLVEN", "url": "https://omabrowser.org/oma/group/CHMLVEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y934", "url": "https://www.orthodb.org/?gene=A0A8V0Y934", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHH4", "url": "https://www.orthodb.org/?gene=A0A8V0YHH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM88", "url": "https://www.orthodb.org/?gene=A0A8V0YM88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM96", "url": "https://www.orthodb.org/?gene=A0A8V0YM96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46538", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46538", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46538:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46538:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y934", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y934", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y934-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96", "database": 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"MAFANFRRILRLSTFEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKVYKAKNKETGALAAAKVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSNRALRELVAEAKAEVLEEIEDSRDEAEDDDSSESASLPGKHKRDPSEVSQLSFDGDKPPDSSSLKTTNGPVATEKEMVNGQSDKVLDERISSDSDKLVNSHSTKTLASSGPDEGKATPGKPDIISLSGRRGSSAEGDKQPMPGSKERRSMVDRPESSHLENFPEEKLANGSLDSSAVFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHNKTLKRTRKFVVDGVEVSVTTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDDFAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHIHSSGSAAEQREKIKQFSQQEEKRQKAERLHQQQKHETQMKDMLAQCESNTNELQQLQNEKCHLLIEHETQKLKSLDENHNLHMKEWRDKLRPRKKALEDELNQKKREQEMFFKLSVEGFPESGPLSRAHDWGGQFLWFTCTVS", "length": 971, "header": "tr|A0A8V0YM96-1|A0A8V0YM96_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=1 CANONICAL=A0A8V0YM96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y934/entry", "sequence": { "sequence": "MVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSNRALRELVAEAKAEVLEEIEDSRDEAEDDDSSESASLPGKHKRDPSEVSQLSFDGDKPPDSSSLKTTNGPVATEKEMVNGQSDKVLDERISSDSDKLVNSHSTKTLASSGPDEGKATPGKPDIISLSGRRGSSAEGDKQPMPGSKERRSMVDRPESSHLENFPEEKLANGSLDSSAVFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHNKTLKRTRKFVVDGVEVSVTTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDDFAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHIHSSGSAAEQREKIKQFSQQEEKRQKAERLHQQQKHETQMKDMLAQCESNTNELQQLQNEKCHLLIEHETQKLKSLDENHNLHMKEWRDKLRPRKKALEDELNQKKREQEMFFKLSVEADEQTPASPTKHTKFIPFSSTESS", "length": 891, "header": "tr|A0A8V0Y934-1|A0A8V0YM96_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=1 CANONICAL=A0A8V0YM96-1" }, "locus": { "chromosome": "13", "start_pos": 8459984, "end_pos": 8430284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029594.1", "url": "https://www.ensembl.org/id/ENSGALT00010029594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017215.1", "url": "https://www.ensembl.org/id/ENSGALP00010017215.1" } ] } }, { "isoform_ac": "A0A8V0YHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH4/entry", "sequence": { "sequence": "MAFANFRRILRLSTFEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKVYKAKNKETGALAAAKVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSNRALRELVAEAKAEVLEEIEDSRDEAEDDDSSESASLPGKHKRDPSEVSQLSFDGDKPPDSSSLKTTNGPVATEKEMVNGQSDKVLDERISSDSDKLVNSHSTKTLASSGPDEGKATPGKPDIISLSGRRGSSAEGDKQPMPGSKERRSMVDRPESSHLENFPEEKLANGSLDSSAVFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHNKTLKRTRKFVVDGVEVSVTTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDDFAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHIHSSGSAAEQREKIKQFSQQEEKRQKAERLHQQQKHETQMKDMLAQCESNTNELQQLQNEKCHLLIEHETQKLKSLDENHNLHMKEWRDKLRPRKKALEDELNQKKREQEMFFKLSVEADEQTPASPTKHTKFIPFSSTESS", "length": 969, "header": "tr|A0A8V0YHH4-1|A0A8V0YM96_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=1 CANONICAL=A0A8V0YM96-1" }, "locus": { "chromosome": "13", "start_pos": 8459984, "end_pos": 8420224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029605.1", "url": "https://www.ensembl.org/id/ENSGALT00010029605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017223.1", "url": "https://www.ensembl.org/id/ENSGALP00010017223.1" } ] } }, { "isoform_ac": "A0A8V0YM88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM88/entry", "sequence": { "sequence": "MGPCSALWGAVGSACRAQAVVCGGDVPWGGLEPQQCREGTGKVSAWCERAASLRRKWQNERFVFPQPYPADLSRWHPELTVIPLSLFPQIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSNRALRELVAEAKAEVLEEIEDSRDEAEDDDSSESASLPGKHKRDPSEVSQLSFDGDKPPDSSSLKTTNGPVATEKEMVNGQSDKVLDERISSDSDKLVNSHSTKTLASSGPDEGKATPGKPDIISLSGRRGSSAEGDKQPMPGSKERRSMVDRPESSHLENFPEEKLANGSLDSSAVFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHNKTLKRTRKFVVDGVEVSVTTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDDFAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHIHSSGSAAEQREKIKQFSQQEEKRQKAERLHQQQKHETQMKDMLAQCESNTNELQQLQNEKCHLLIEHETQKLKSLDENHNLHMKEWRDKLRPRKKALEDELNQKKREQEMFFKLSVEADEQTPASPTKHTKFIPFSSTESS", "length": 951, "header": "tr|A0A8V0YM88-1|A0A8V0YM88_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=1 CANONICAL=A0A8V0YM96-1" }, "locus": { "chromosome": "13", "start_pos": 8459984, "end_pos": 8443588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029590.1", "url": "https://www.ensembl.org/id/ENSGALT00010029590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017211.1", "url": "https://www.ensembl.org/id/ENSGALP00010017211.1" } ] } }, { "isoform_ac": "A0A8V0YM96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96/entry", "sequence": { "sequence": "MAFANFRRILRLSTFEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKVYKAKNKETGALAAAKVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPFVSKVTSNRALRELVAEAKAEVLEEIEDSRDEAEDDDSSESASLPGKHKRDPSEVSQLSFDGDKPPDSSSLKTTNGPVATEKEMVNGQSDKVLDERISSDSDKLVNSHSTKTLASSGPDEGKATPGKPDIISLSGRRGSSAEGDKQPMPGSKERRSMVDRPESSHLENFPEEKLANGSLDSSAVFPGSRSKGDSDSGSTSASESMDLTISLSADLSLNRESGSISLKDSRMHNKTLKRTRKFVVDGVEVSVTTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQAQLNSKHQLQLDQMLRRFEQEMTAKKKFYDTELENLERQQKQQIEKMEQDHSLRRREEAKRIRLEQERDHVKFMEQLKQKKKEVKNEVEKLPRQQRKENMKVKMDDFAQRKQTMEQDFLAKQKEDLELAMKNITAQNKKEICDKERECLNKKQQLMRDREACIWDLEERQQQEKHQLIKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKIRQQQEKARLPKIQRSEGKTRMAMYKKSLHIHSSGSAAEQREKIKQFSQQEEKRQKAERLHQQQKHETQMKDMLAQCESNTNELQQLQNEKCHLLIEHETQKLKSLDENHNLHMKEWRDKLRPRKKALEDELNQKKREQEMFFKLSVEGFPESGPLSRAHDWGGQFLWFTCTVS", "length": 971, "header": "tr|A0A8V0YM96-1|A0A8V0YM96_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=1 CANONICAL=A0A8V0YM96-1" }, "locus": { "chromosome": "13", "start_pos": 8460244, "end_pos": 8420224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029600.1", "url": "https://www.ensembl.org/id/ENSGALT00010029600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017221.1", "url": "https://www.ensembl.org/id/ENSGALP00010017221.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M334-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "STK10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETNSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSAEFRDFLKTALDKNPETRPSAAQLLEHPFVSSVTSNKALRELVAEAKAEVMEEIEDGRDEGDEEDAVEAASPLENHTRDSSEVSQLSIDADKLLKESPFTPPPPSQPQDGANGPSEPPGHGALPATSPLDVAPGNENGQAVPVPLRKFRPVSMGARIQVSEEKQAADQGGDLSPAASRSQKASQSRPNSSALETLRSELTNGSLELPTPGAQSLSKRDSDCGSVSTSGSTDFGTSLSADMSVNKESGSLSIKDSRLHNKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFFDIELENLERQQKQQVEKMEQDHAVRRREEAKRIRLEQERDYAKFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFLAKQKEDLELAMKRITADNRREICDKERECLTRKQELLRDREAALWEMEEHHLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLIEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKMNEESECANPTSPNKVTKFFPYSSADAAS", "length": 967 }, "evidence": [ { "id": "A0A8V0YM96", "url": "https://omabrowser.org/oma/group/A0A8V0YM96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BK52-1", "protein_name": "Serine/threonine-protein kinase 10", "gene_name": "STK10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETNSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSAEFRDFLKTALDKNPETRPSAAQLLEHPFVSSVTSNKALRELVAEAKAEVMEEIEDGRDEGDEEDAVEAASPLENHTRDSSEVSQLSIDADKLLKESPFTPPPPSQPQDGANGPSEPPGHGALPATSPLDVAPGNENGQAVPVPLRKFRPVSMGARIQVSEEKQAADQGGDLSPAASRSQKASQSRPNSSALETLRSELTNGSLELPTPGAQSLSKRDSDCGSVSTSGSTDFGTSLSADMSVNKESGSLSIKDSRLHNKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFFDIELENLERQQKQQVEKMEQDHAVRRREEAKRIRLEQERDYAKFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFLAKQKEDLELAMKRITADNRREICDKERECLTRKQELLRDREAALWEMEEHHLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLIEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKMNEESECANPTSPNKVTKFFPYSSADAA", "length": 966 }, "evidence": [ { "id": "A0A8V0YM96", "url": "https://omabrowser.org/oma/group/A0A8V0YM96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PTG8-1", "protein_name": "Serine/threonine-protein kinase 10", "gene_name": "Stk10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQLLQHPFVSTVTSNKALRELVAEAKAEVMEEIEDGKEDGSEKDAVSAVPPPVNHTQDSSANGTQPSLNSDKLLQDSSTPLPPSQPQEPVNGPCNQPSGDGSPQNTSPADEVSKNDNGLKVPVPLRKSRPLSVDARIQVTEEKQITDQAENPSSAASKPPKVNQSRPNSSALETLGVETLANGGLELPGSVTPNHSKRASDCSNLSTSESMDYGTSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSTKHELQLEQMHRRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYARFQEQLKQMKKEVKRSIEKALRKQRQESMRMGQDSHTQKKQRLDRDFVAKQKEDLELAMKKLTAENRREICDKERDCLNKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHINGAGSASEQREKVKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMNELQQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLRPRKKALEEDLNQKKREQEMFFRLSEEAETRPTTPNRASKFFPYSSGDAS", "length": 967 }, "evidence": [ { "id": "A0A8V0YM96", "url": "https://omabrowser.org/oma/group/A0A8V0YM96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94804-1", "protein_name": "Serine/threonine-protein kinase 10", "gene_name": "STK10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEEIEDGRDEGEEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGDRSLQTTSPPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANRSQKASQSRPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLSTDLSLNKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKSERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKLSEEAECPNPSTPSKAAKFFPYSSADAS", "length": 968 }, "evidence": [ { "id": "A0A8V0YM96", "url": "https://omabrowser.org/oma/group/A0A8V0YM96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of lymphocyte migration", "id": "GO:2000401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000401", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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"id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { 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"A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YML4-1", "uniprot_ac": "A0A8V0YML4", "uniprot_id": "A0A8V0YML4_CHICK", "mass": { "chemical_mass": 52356.0, "monoisotopic_mass": 52356.0 }, "refseq": { "ac": "NP_990143", "name": "neuronal acetylcholine receptor subunit beta-3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" }, "gene_names": [ { "name": "CHRNB3", "type": "recommended", "evidence": [ { "id": "A0A8V0YML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML4" } ] }, { "name": "CHRNB3", "type": "synonym", "evidence": [ { "id": "NP_990143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" } ] }, { "name": "NACHR", "type": "synonym", "evidence": [ { "id": "NP_990143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" } ] } ], "protein_names": [ { "name": "Cholinergic receptor nicotinic beta 3 subunit", "type": 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acetylcholine receptor (nAChR) beta 3 subunit", "type": "synonym", "evidence": [ { "id": "NP_990143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" } ] }, { "name": "nicotinic acetylcholine receptor beta 3 subunit", "type": "synonym", "evidence": [ { "id": "NP_990143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X83739.2, SRR13267659.18062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1. On Dec 3, 2021 this sequence version replaced NP_990143.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHRNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML4", "locus": { "chromosome": "Z", "start_pos": 54303802, "end_pos": 54314326, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012425", "url": "https://www.ensembl.org/id/ENSGALG00010012425" } ] } } ], "crossref": [ { "id": "A0A8V0YML4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YML4", "database": 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"categories": [ "Protein" ] }, { "id": "A0A8V0YML4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCLMLCVLCWSRSDVAALGSVVENEDALLRHLFQGYQKWVRPVENSNDTIKVLFGLKISQLVDVDEKNQLMTTNVWLKQEWMDHKLSWNPEEYGGITAIRVPSESLWLPDIVLFENADGRFEGSLMTKAIVKYNGVVTWMPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDLILVDENVDRKDFFDNGEWEILNAKGMKGNRKDGLYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLQKLPRLLCMKGHVDRYSFSDTEEKETTLKSKLPGKQKHKQAKDGEKVVIAFLEKAADSIRYISRHVKKEHFIRQVVQDWKFVAQVLDRIFLWLFLVVSVTGSVLIFTPALQMWLNSTL", "length": 455, "header": "tr|A0A8V0YML4-1|A0A8V0YML4_CHICK Isoform 1 of Cholinergic receptor nicotinic beta 3 subunit OS=Gallus gallus OX=9031 GN=CHRNB3 PE=3 SV=1 CANONICAL=A0A8V0YML4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9F1/entry", "sequence": { "sequence": "MLCLMLCVLCWSRSDVAALGSVVENEDALLRHLFQGYQKWVRPVENSNDTIKVLFGLKISQLVDVDEKNQLMTTNVWLKQEWMDHKLSWNPEEYGGITAIRVPSESLWLPDIVLFENADGRFEGSLMTKAIVKYNGVVTWMPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDLILVDENVDRKDFFDNGEWEILNAKGMKGNRKDGLYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLQKLPRLLCMKGHVDRYSFSDTEEKETTLKSKLPGKQKHKQAKDGEKVVIAFLEKAADSIRYISRHVKKEHFIRQGCASTHDAELPS", "length": 423, "header": "tr|A0A8V0Y9F1-1|A0A8V0YML4_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic beta 3 subunit OS=Gallus gallus OX=9031 GN=CHRNB3 PE=3 SV=1 CANONICAL=A0A8V0YML4-1" }, "locus": { "chromosome": "Z", "start_pos": 54314220, "end_pos": 54305825, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029791.1", "url": "https://www.ensembl.org/id/ENSGALT00010029791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017344.1", "url": "https://www.ensembl.org/id/ENSGALP00010017344.1" } ] } }, { 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"https://www.ensembl.org/id/ENSGALT00010029803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017352.1", "url": "https://www.ensembl.org/id/ENSGALP00010017352.1" } ] } }, { "isoform_ac": "A0A8V0YML4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML4/entry", "sequence": { "sequence": "MLCLMLCVLCWSRSDVAALGSVVENEDALLRHLFQGYQKWVRPVENSNDTIKVLFGLKISQLVDVDEKNQLMTTNVWLKQEWMDHKLSWNPEEYGGITAIRVPSESLWLPDIVLFENADGRFEGSLMTKAIVKYNGVVTWMPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDLILVDENVDRKDFFDNGEWEILNAKGMKGNRKDGLYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLQKLPRLLCMKGHVDRYSFSDTEEKETTLKSKLPGKQKHKQAKDGEKVVIAFLEKAADSIRYISRHVKKEHFIRQVVQDWKFVAQVLDRIFLWLFLVVSVTGSVLIFTPALQMWLNSTL", "length": 455, "header": "tr|A0A8V0YML4-1|A0A8V0YML4_CHICK Isoform 1 of Cholinergic receptor nicotinic beta 3 subunit OS=Gallus gallus OX=9031 GN=CHRNB3 PE=3 SV=1 CANONICAL=A0A8V0YML4-1" }, "locus": { "chromosome": "Z", "start_pos": 54314220, "end_pos": 54305239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029809.1", "url": "https://www.ensembl.org/id/ENSGALT00010029809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017355.1", "url": "https://www.ensembl.org/id/ENSGALP00010017355.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395604", "resource": "KEGG Pathway" }, { "id": "R-GGA-629594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629594", "resource": "Reactome", "description": "Highly calcium permeable postsynaptic nicotinic acetylcholine receptors" }, { "id": "R-GGA-629597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629597", "resource": "Reactome", "description": "Highly calcium permeable nicotinic acetylcholine receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BMN3-1", "protein_name": "Neuronal acetylcholine receptor subunit beta-3", "gene_name": "Chrnb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFLRVFLALSATLSGSWVTLTATAGLSSVAEHEDALLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEDYGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCMKDPRDRFSFPDGTESKGTVRGKFPGKKKQTPTSDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTASVLGSVLIFIPALKMWIHRFH", "length": 464 }, "evidence": [ { "id": "A0A8V0YML4", "url": "https://omabrowser.org/oma/group/A0A8V0YML4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": 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"uniprot_canonical_ac": "A0A8V0YMT9-1", "uniprot_ac": "A0A8V0YMT9", "uniprot_id": "A0A8V0YMT9_CHICK", "mass": { "chemical_mass": 208348.0, "monoisotopic_mass": 208348.0 }, "refseq": { "ac": "NP_990272", "name": "ATP-dependent chromatin remodeler CHD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" }, "gene_names": [ { "name": "CHD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ] }, { "name": "CHD-Z", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "CHD1Z", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "CHD1", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "CHDZ", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] } ], "protein_names": [ { "name": "ATP-dependent chromatin remodeler CHD1", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "Chromodomain helicase DNA binding protein 1Z", "type": "synonym", "evidence": [ { "id": "A0A8V0YMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9/entry#names_and_taxonomy" } ] }, { "name": "chromo-helicase DNA-binding protein", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "chromo-helicase-DNA-binding on the Z chromosome protein", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "chromobox-helicase-DNA binding protein Z", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] }, { "name": "chromodomain helicase DNA binding protein 1-Z", "type": "synonym", "evidence": [ { "id": "NP_990272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF004397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1. On Oct 25, 2021 this sequence version replaced NP_990272.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9", "locus": { "chromosome": "Z", "start_pos": 52001109, "end_pos": 51952660, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012470", "url": "https://www.ensembl.org/id/ENSGALG00010012470" } ] } } ], "crossref": [ { "id": "cd18661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395783", "url": "https://www.ncbi.nlm.nih.gov/gene/395783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395783", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395783", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVQIRDD", "url": "https://omabrowser.org/oma/group/WVQIRDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9P5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMT9", "url": "https://www.orthodb.org/?gene=A0A8V0YMT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGHSDEESVRNSSGESSRSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSESGSESGSQSESESDTSREKKQVQAKPPKADGSEFWKSSPSILAVQRSAVLKKQQQQQKAASSDSGSEEDSSSSEDSADDSSSETKKKKHKDEDWQMSGSGSVSGTGSDSESEEDGDKSSCEESESDYEPKNKVKSRKPPSRIKPKSGKKSTGQKKRQLDSSEEEEDDDEDYDKRGSRRQATVNVSYKEAEETKTDSDDLLEVCGEDVPQTEEDEFETIEKFMDSRIGRKGATGASTTIYAVEADGDPNAGFEKSKELGEIQYLIKWKGWSHIHNTWETEETLKQQNVKGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQARIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHESLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSRNWEEIIPESQRRRIEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSITERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAVARDAELVDKSETDLRRLGELVHNGCIKALKDNSSGQERAGGRLGKVKGPTFRISGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPCHTKAAHFDIDWGKEDDSNLLVGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRNKKNKMKASKIKEEIKSDSSPQPSEKSDEDDEEEDNKDEIVSVKHLHKKIKTEKENEEKPEPDIGIKKEAEEKRETKEKENKRELKREKKEKEDKKELKEKDNKEKRENKVKESTQKEKEVKEEKVNEIKSENKEKSKKIPLLDTPVHITATSEPVPISEESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHNDQNISSNVNTHVIRNPDVERLKETTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDAYKKSDSRKRPYSAFSNGKDHRDWDHYKQDSRYYSDSKHRKLDDHRSRDHRSNLEGNLKDSRGHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGPRSPLDQRSPYGSRSPLGHRSPFEHSSDHKSTPEHTWSSRKT", "length": 1808, "header": "tr|A0A8V0YMT9-1|A0A8V0YMT9_CHICK Isoform 1 of Chromodomain helicase DNA binding protein 1Z OS=Gallus gallus OX=9031 GN=CHD1 PE=4 SV=1 CANONICAL=A0A8V0YMT9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P5/entry", "sequence": { "sequence": "MNGHSDEESVRNSSGESSRSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSESGSESGSQSESESDTSREKKQVQAKPPKADGSEFWKSSPSILAVQRSAVLKKQQQQQKAASSDSGSEEDSSSSEDSADDSSSETKKKKHKDEDWQMSGSGSVSGTGSDSESEEDGDKSSCEESESDYEPKNKVKSRKPPSRIKPKSGKKSTGQKKRQLDSSEEEEDDDEDYDKRGSRRQATVNVSYKEAEETKTDSDDLLEVCGEDVPQTEEDEFETIEKFMDSRIGRKGATGASTTIYAVEADGDPNAGFEKSKELGEIQYLIKWKGWSHIHNTWETEETLKQQNVKGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQARIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHESLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSRNWEEIIPESQRRRIEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSITERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAVARDAELVDKSETDLRRLGELVHNGCIKALKDNSSGQERAGGRLGKVKGPTFRISGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPCHTKAAHFDIDWGKEDDSNLLVGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRNKKNKMKASKIKEEIKSDSSPQPSEKSDEDDEEEDNKVNEIKSENKEKSKKIPLLDTPVHITATSEPVPISEESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHNDQNISSNVNTHVIRNPDVERLKETTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDAYKKSDSRKRPYSAFSNGKDHRDWDHYKQDSRYYSDSKHRKLDDHRSRDHRSNLEGNLKDSRGHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGPRSPLDQRSPYGSRSPLGHRSPFEHSSDHKSTPEHTWSSRKT", "length": 1720, "header": "tr|A0A8V0Y9P5-1|A0A8V0YMT9_CHICK Computationally mapped isoform of Chromodomain helicase DNA binding protein 1Z OS=Gallus gallus OX=9031 GN=CHD1 PE=4 SV=1 CANONICAL=A0A8V0YMT9-1" }, "locus": { "chromosome": "Z", "start_pos": 51999896, "end_pos": 51954591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030014.1", "url": "https://www.ensembl.org/id/ENSGALT00010030014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017447.1", "url": "https://www.ensembl.org/id/ENSGALP00010017447.1" } ] } }, { "isoform_ac": "A0A8V0YMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9/entry", "sequence": { "sequence": "MNGHSDEESVRNSSGESSRSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSESGSESGSQSESESDTSREKKQVQAKPPKADGSEFWKSSPSILAVQRSAVLKKQQQQQKAASSDSGSEEDSSSSEDSADDSSSETKKKKHKDEDWQMSGSGSVSGTGSDSESEEDGDKSSCEESESDYEPKNKVKSRKPPSRIKPKSGKKSTGQKKRQLDSSEEEEDDDEDYDKRGSRRQATVNVSYKEAEETKTDSDDLLEVCGEDVPQTEEDEFETIEKFMDSRIGRKGATGASTTIYAVEADGDPNAGFEKSKELGEIQYLIKWKGWSHIHNTWETEETLKQQNVKGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQARIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHESLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSRNWEEIIPESQRRRIEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSITERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAVARDAELVDKSETDLRRLGELVHNGCIKALKDNSSGQERAGGRLGKVKGPTFRISGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPCHTKAAHFDIDWGKEDDSNLLVGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRNKKNKMKASKIKEEIKSDSSPQPSEKSDEDDEEEDNKDEIVSVKHLHKKIKTEKENEEKPEPDIGIKKEAEEKRETKEKENKRELKREKKEKEDKKELKEKDNKEKRENKVKESTQKEKEVKEEKVNEIKSENKEKSKKIPLLDTPVHITATSEPVPISEESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHNDQNISSNVNTHVIRNPDVERLKETTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDAYKKSDSRKRPYSAFSNGKDHRDWDHYKQDSRYYSDSKHRKLDDHRSRDHRSNLEGNLKDSRGHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGPRSPLDQRSPYGSRSPLGHRSPFEHSSDHKSTPEHTWSSRKT", "length": 1808, "header": "tr|A0A8V0YMT9-1|A0A8V0YMT9_CHICK Isoform 1 of Chromodomain helicase DNA binding protein 1Z OS=Gallus gallus OX=9031 GN=CHD1 PE=4 SV=1 CANONICAL=A0A8V0YMT9-1" }, "locus": { "chromosome": "Z", "start_pos": 51999896, "end_pos": 51954591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030002.1", "url": "https://www.ensembl.org/id/ENSGALT00010030002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017438.1", "url": "https://www.ensembl.org/id/ENSGALP00010017438.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395783", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395783", "resource": "KEGG Pathway" }, { "id": "R-GGA-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K5T4-1", "protein_name": "Chromodomain helicase DNA binding protein 1", "gene_name": "Chd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAVGKVGRTVLISSPHCQSEDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAMLRKQTQQPQQQRPASSNSGSEEDSSSSEDSDASSSDVKRKKHNDEDWQMSGSGSPSQSGSDSESEDERDKSSCDGTESDYEPKNKVKSRKPQNRSKSKSGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQTEDEEFETIERFMDCRVGRKGATGATTTIYAIEADGDPNAGFEKSKEPGDVQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRRQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEDIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTERAGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKTRAKKNKAMKSIKVKEEIKSDSSPLPSERSEEEDDNVNDSKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNVPTTHVIRNPDMERLKENTNHDDSSRDGYSSDRHLSQCHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHREWDHYRQDSRYYSDREKHRKLDDHRSREHRPSVEGSLKDRCHSDHRSHSDHRMHSDHRSSTEHTHHKSSRDYRYLSDWQLDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSSRKT", "length": 1711 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1LUM8-1", "protein_name": "Chromodomain helicase DNA binding protein 1", "gene_name": "CHD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDNSRDNKVQAKPPKVDGAEFWKSSPSILAVQRSAMLKKQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIIGQKKRQIDSSEEEDDDEEEYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEAGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYIIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSDKSDEDDDKLSESKSESKERSKKSSVLDAPVHITAGGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPERGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNNDQNSSLNTQVIRNPDVERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRTHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1711 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IV99-1", "protein_name": "Protein CHROMATIN REMODELING 5", "gene_name": "CHR5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAFFRNYSNDTVSHNVLDENEERQNAATFQSSPLNEDVDGTYSERGFDMNMDVQYQSDPEPGCSIRQPNETAVDNVADPVDSHYQSSTKRLGVTGRWGSTFWKDCQPMGQREGSDPAKDSQSGYKEAYHSEDNHSNDRSEKLDSENENDNENEEEDNEMNKHQSGQADVPADEMLSDEYYEQDEDNQSDHVHYKGYSNPTNSRSLPKAGSAVHSNSRTSRAIHKNIHYSDSNHDHNGDADMDYEEEEDEDDPEDADFEPYDAADDGGASKKHGQGWDVSDEDPESDEEIDLSDYEDDYGTKKPKVRQQSKGFRKSSAGLERKSFHVSSRQKRKTSYQDDDSEEDSENDNDEGFRSLARRGTTLRQNNGRSTNTIGQSSEVRSSTRSVRKVSYVESEDSEDIDDGKNRKNQKDDIEEEDADVIEKVLWHQLKGMGEDVQTNNKSTVPVLVSQLFDTEPDWNEMEFLIKWKGQSHLHCQWKTLSDLQNLSGFKKVLNYTKKVTEEIRYRTALSREEIEVNDVSKEMDLDIIKQNSQVERIIADRISKDGLGDVVPEYLVKWQGLSYAEATWEKDVDIAFAQVAIDEYKAREVSIAVQGKMVEQQRTKGKASLRKLDEQPEWLIGGTLRDYQLEGLNFLVNSWLNDTNVILADEMGLGKTVQSVSMLGFLQNTQQIPGPFLVVVPLSTLANWAKEFRKWLPGMNIIVYVGTRASREVCQQYEFYNEKKVGRPIKFNALLTTYEVVLKDKAVLSKIKWIYLMVDEAHRLKNSEAQLYTALLEFSTKNKLLITGTPLQNSVEELWALLHFLDPGKFKNKDEFVENYKNLSSFNESELANLHLELRPHILRRVIKDVEKSLPPKIERILRVEMSPLQKQYYKWILERNFHDLNKGVRGNQVSLLNIVVELKKCCNHPFLFESADHGYGGDINDNSKLDKIILSSGKLVILDKLLVRLRETKHRVLIFSQMVRMLDILAEYLSLRGFQFQRLDGSTKAELRQQAMDHFNAPASDDFCFLLSTRAGGLGINLATADTVVIFDSDWNPQNDLQAMSRAHRIGQQEVVNIYRFVTSKSVEEEILERAKRKMVLDHLVIQKLNAEGRLEKRETKKGSNFDKNELSAILRFGAEELFKEDKNDEESKKRLLSMDIDEILERAEQVEEKHTDETEHELLGAFKVANFCNAEDDGSFWSRWIKPDSVVTAEEALAPRAARNTKSYVDPSHPDRTSKRKKKGSEPPEHTERSQKRRKTEYFVPSTPLLEGTSAQVRGWSYGNLPKRDAQRFYRTVMKFGNHNQMACIAEEVGGVVEAAPEEAQVELFDALIDGCKESVETGNFEPKGPVLDFFGVPVKANELLKRVQGLQLLSKRISRYNDPISQFRVLSYLKPSNWSKGCGWNQIDDARLLLGILYHGFGNWEKIRLDESLGLTKKIAPVELQHHETFLPRAPNLKERATALLEMELAAAGGKNTNAKASRKNSKKVKDNLINQFKAPARDRRGKSGPANVSLLSTKDGPRKTQKAEPLVKEEGEMSDDGEVYEQFKEQKWMEWCEDVLADEIKTLGRLQRLQTTSADLPKEKVLFKIRRYLEILGRRIDAIVLEHEEDLYKQDRMTMRLWNYVSTFSNLSGDRLNQIYSKLKQEKEEEEGVGPSHLNGSRNFQRQQKFKTAGNSQGSQQVHKGIDTAKFEAWKRRRRTENDVQTERPTITNSNSLGILGPGPLDRSHRARQTGFPPR", "length": 1724 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3HNU4-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 1", "gene_name": "Chd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGHSDEESVRNGSGESSQSEDDSGSASGSGSGSSSGSSSGGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAILKKQPQQPQQVHAASSNSGSEEDSSSSEDSDDSSSEVKRKKHNDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQSRCKSKNGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEDMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRVGRRGATGATTTIYAVEADGDPNAGFEKNKEPGDIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQSCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHLQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTDRTGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKRYTIPCHTKAAHFDIDWGREDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKTRTKKNKTTKSIKIKEEIKSDSSPLPSEKSDEDDDKLNESKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSSITTHVIRNPDMERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDCYKKSDSRKRPYSSLSNGKDHREWDHYKQDSRYYSDREKHRKLDDHRSREHRSSLEGSLKDRCHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRFLSDWQMDHRAASTGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1710 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14646-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "CHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRERSKKSSVSDAPVHITASGEPVPISEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1710 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32657-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "CHD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAAKDISTEVLQNPELYGLRRSHRAAAHQQNYFNDSDDEDDEDNIKQSRRKRMTTIEDDEDEFEDEEGEEDSGEDEDEEDFEEDDDYYGSPIKQNRSKPKSRTKSKSKSKPKSQSEKQSTVKIPTRFSNRQNKTVNYNIDYSDDDLLESEDDYGSEEALSEENVHEASANPQPEDFHGIDIVINHRLKTSLEEGKVLEKTVPDLNNCKENYEFLIKWTDESHLHNTWETYESIGQVRGLKRLDNYCKQFIIEDQQVRLDPYVTAEDIEIMDMERERRLDEFEEFHVPERIIDSQRASLEDGTSQLQYLVKWRRLNYDEATWENATDIVKLAPEQVKHFQNRENSKILPQYSSNYTSQRPRFEKLSVQPPFIKGGELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYLFDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAIISLGVTDGNKYTKKNEPNAGELSAILKFGAGNMFTATDNQKKLEDLNLDDVLNHAEDHVTTPDLGESHLGGEEFLKQFEVTDYKADIDWDDIIPEEELKKLQDEEQKRKDEEYVKEQLEMMNRRDNALKKIKNSVNGDGTAANSDSDDDSTSRSSRRRARANDMDSIGESEVRALYKAILKFGNLKEILDELIADGTLPVKSFEKYGETYDEMMEAAKDCVHEEEKNRKEILEKLEKHATAYRAKLKSGEIKAENQPKDNPLTRLSLKKREKKAVLFNFKGVKSLNAESLLSRVEDLKYLKNLINSNYKDDPLKFSLGNNTPKPVQNWSSNWTKEEDEKLLIGVFKYGYGSWTQIRDDPFLGITDKIFLNEVHNPVAKKSASSSDTTPTPSKKGKGITGSSKKVPGAIHLGRRVDYLLSFLRGGLNTKSPSADIGSKKLPTGPSKKRQRKPANHSKSMTPEITSSEPANGPPSKRMKALPKGPAALINNTRLSPNSPTPPLKSKVSRDNGTRQSSNPSSGSAHEKEYDSMDEEDCRHTMSAIRTSLKRLRRGGKSLDRKEWAKILKTELTTIGNHIESQKGSSRKASPEKYRKHLWSYSANFWPADVKSTKLMAMYDKITESQKK", "length": 1468 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40201-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "Chd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGHSDEESVRNGSGESSQSGDDCGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAMLRKQPQQAQQQRPASSNSGSEEDSSSSEDSDDSSSGAKRKKHNDEDWQMSGSGSPSQSGSDSESEEERDKSSCDGTESDYEPKNKVRSRKPQNRSKSKNGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEDEEFETIERVMDCRVGRKGATGATTTIYAVEADGDPNAGFERNKEPGDIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLSVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTERAGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKREAQRLCGAGGSKRRKTRAKKSKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLNDSKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNVATTHVIRNPDMERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHREWDHYRQDSRYYSDREKHRKLDDHRSREHRPSLEGGLKDRCHSDHRSHSDHRMHSDHRSSSEHTHHKSSRDYRYLSDWQLDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSSRKT", "length": 1711 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KU24-1", "protein_name": "ATP-dependent chromatin remodeler Chd1", "gene_name": "Chd1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 1883 }, "evidence": [ { "id": "A0A8V0YMT9", "url": "https://omabrowser.org/oma/group/A0A8V0YMT9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1080, "end_pos": 1082, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1180, "end_pos": 1182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1604, "end_pos": 1606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": 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[ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", 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"id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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"activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": 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"Nuclear pore complex protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YN32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as a component of the nuclear pore complex (NPC).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG74#function" }, { "database": "UniProtKB", "id": "RU365072", "url": "https://www.uniprot.org/uniprotkb/RU365072#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y4#function" }, { "database": "UniProtKB", "id": "A0A8V0YN32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32#function" } ] }, { "annotation": "Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG74#function" }, { "database": "UniProtKB", "id": "ARBA00056880", "url": "https://www.uniprot.org/uniprotkb/ARBA00056880#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP107", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32", "locus": { "chromosome": "1", "start_pos": 35400312, "end_pos": 35375012, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012600", "url": "https://www.ensembl.org/id/ENSGALG00010012600" } ] } } ], "crossref": [ { "id": "A0A8V0YN32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN32", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9Y4", "url": "https://www.orthodb.org/?gene=A0A8V0Y9Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG74", "url": "https://www.orthodb.org/?gene=A0A8V0YG74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN32", "url": "https://www.orthodb.org/?gene=A0A8V0YN32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13003:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13003:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRNSFGEVLSPLSTEMAKSGRKQSSQKRVSILTSLDDSIGSMTPRGQVIPRTPSSLFRQPFTALSRSSLKQTDISTILGAAGKSPLILQNSGLLGNQSMLDESNWTAMLSPQQTGMFANLDLTEDVTTSAVLLREDDPGEAATMSMYSDFLQSFLKHTSTTIFDLVDEYESICNNQVNILGKIVYRATPGQQKFSKTASVLWLLKQEMVTWRLLSSLYRDRIQSALEDETAFDITVLNASEKTSVDNLFQKDALVRQSQLVVDWLESIAKDEIGNFSDNIEFYAKSVYWENTLHILKQRQLSTYIGSSRPLVTELDPDAPIRQKLPLDDLDREDDARLLKYLFTLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDPNINGGNEVQPVEGNPYRCIWKICCWRMAEEEQFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDTLVEQEIRTSVVTTEEVEELPREYLETNWTTERVFEELQATDKKRVIEENQEHYRVIQKFIILGDVDGLMEEFSRWLSKDRSVLPGHLLRFMTHLILFFRTLGLQTKEEVSVEVLKTYIQRMISEKHTDLIAFYVSHLPPELAVVQYALFLEDVTESDQRHHCLELAKEAGLDVAAITKTVVENIRKKDAGDFSHHDHMLDTGTTEADRLKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHEAAKDVFVKIPQDSIAEIYNQWEEQGIEASLPAEDDNAIREHLCIRAYLEAHEIFNKWFQHMNSAPQKPPLLPQASFTEKVAHEHKEKKYEVALLWLTILIRIRAARAVTCKVDYGIWKSFLDGLTSDVKEKMYNVLLFVDGGWMVDVREDAEEDPERTHQMILLRKLCLPMMCFLLHTVLHSTGQYQECLRLADMVASERHKLYSVFSKEELRKFLQKLRESSLMLLDQDLDPLGYEIQS", "length": 937, "header": "tr|A0A8V0YN32-1|A0A8V0YN32_CHICK Isoform 1 of Nuclear pore complex protein OS=Gallus gallus OX=9031 GN=NUP107 PE=1 SV=1 CANONICAL=A0A8V0YN32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y4/entry", "sequence": { "sequence": "MAKSGRKQSSQKRVSILTSLDDSIGSMTPRGQVIPRTPSSLFRQPFTALSRSSLKQTDISTILGAAGKSPLILQNSGLLGNQSMLDESNWTAMLSPQQTGMFANLDLTEDVTTSAVLLREDDPGEAATMSMYSDFLQSFLKHTSTTIFDLVDEYESICNNQVNILGKIVYRATPGQQKFSKTASVLWLLKQEMVTWRLLSSLYRDRIQSALEDETAFDITVLNASEKTSVDNLFQKDALVRQSQLVVDWLESIAKDEIGNFSDNIEFYAKSVYWENTLHILKQRQLSTYIGSSRPLVTELDPDAPIRQKLPLDDLDREDDARLLKYLFTLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDPNINGGNEVQPVEGNPYRCIWKICCWRMAEEEQFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDTLVEQEIRTSVVTTEEVEELPREYLETNWTTERVFEELQATDKKRVIEENQEHYRVIQKFIILGDVDGLMEEFSRWLSKDRSVLPGHLLRFMTHLILFFRTLGLQTKEEVSVEVLKTYIQRMISEKHTDLIAFYVSHLPPELAVVQYALFLEDVTESDQRHHCLELAKEAGLDVAAITKTVVENIRKKDAGDFSHHDHMLDTGTTEADRLKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHEAAKDVFVKIPQDSIAEIYNQWEEQGIEASLPAEDDNAIREHLCIRAYLEAHEIFNKWFQHMNSAPQKPPLLPQASFTEKVAHEHKEKKYEVDYGIWKSFLDGLTSDVKEKMYNVLLFVDGGWMVDVREDAEEDPERTHQMILLRKLCLPMMCFLLHTVLHSTGQYQECLRLADMVASERHKLYSVFSKEELRKFLQKLRESSLMLLDQDLDPLGYEIQS", "length": 900, "header": "tr|A0A8V0Y9Y4-1|A0A8V0YN32_CHICK Computationally mapped isoform of Nuclear pore complex protein OS=Gallus gallus OX=9031 GN=NUP107 PE=1 SV=1 CANONICAL=A0A8V0YN32-1" }, "locus": { "chromosome": "1", "start_pos": 35400095, "end_pos": 35376950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030198.1", "url": "https://www.ensembl.org/id/ENSGALT00010030198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017533.1", "url": "https://www.ensembl.org/id/ENSGALP00010017533.1" } ] } }, { "isoform_ac": "A0A8V0YG74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG74/entry", "sequence": { "sequence": "MDRNSFGEVLSPLSTEMAKSGRKQSSQKRVSILTSLDDSIGSMTPRGQVIPRTPSSLFRQPFTALSRSSLKQTDISTILGAAGKSPLILQNSGLLGNQSMLDESNWTAMLSPQQTGMFANLDLTEDVTTSAVLLREDDPGEAATMSMYSDFLQSFLKHTSTTIFDLVDEYESICNNQVNILGKIVYRATPGQQKFSKTASVLWLLKQEMVTWRLLSSLYRDRIQSALEDETAFDITVLNASEKTSVDNLFQKDALVRQSQLVVDWLESIAKDEIGNFSDNIEFYAKSVYWENTLHILKQRQLSTYIGSSRPLVTELDPDAPIRQKLPLDDLDREDDARLLKYLFTLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDPNINGGNEVQPVEGNPYRCIWKICCWRMAEEEQFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDTLVEQEIRTSVVTTEEVEELPREYLETNWTTERVFEELQATDKKRVIEENQEHYRVIQKFIILGDVDGLMEEFSRWLSKDRSVLPGHLLRFMTHLILFFRTLGLQTKRMISEKHTDLIAFYVSHLPPELAVVQYALFLEDVTESDQRHHCLELAKEAGLDVAAITKTVVENIRKKDAGDFSHHDHMLDTGTTEADRLKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHEAAKDVFVKIPQDSIAEIYNQWEEQGIEASLPAEDDNAIREHLCIRAYLEAHEIFNKWFQHMNSAPQKPPLLPQASFTEKVAHEHKEKKYEVDYGIWKSFLDGLTSDVKEKMYNVLLFVDGGWMVDVREDAEEDPERTHQMILLRKLCLPMMCFLLHTVLHSTGQYQECLRLADMVASERHKLYSVFSKEELRKFLQKLRESSLMLLDQDLDPLGYEIQS", "length": 903, "header": "tr|A0A8V0YG74-1|A0A8V0YN32_CHICK Computationally mapped isoform of Nuclear pore complex protein OS=Gallus gallus OX=9031 GN=NUP107 PE=1 SV=1 CANONICAL=A0A8V0YN32-1" }, "locus": { "chromosome": "1", "start_pos": 35400095, "end_pos": 35375065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030182.1", "url": "https://www.ensembl.org/id/ENSGALT00010030182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017525.1", "url": "https://www.ensembl.org/id/ENSGALP00010017525.1" } ] } }, { "isoform_ac": "A0A8V0YN32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN32/entry", "sequence": { "sequence": "MDRNSFGEVLSPLSTEMAKSGRKQSSQKRVSILTSLDDSIGSMTPRGQVIPRTPSSLFRQPFTALSRSSLKQTDISTILGAAGKSPLILQNSGLLGNQSMLDESNWTAMLSPQQTGMFANLDLTEDVTTSAVLLREDDPGEAATMSMYSDFLQSFLKHTSTTIFDLVDEYESICNNQVNILGKIVYRATPGQQKFSKTASVLWLLKQEMVTWRLLSSLYRDRIQSALEDETAFDITVLNASEKTSVDNLFQKDALVRQSQLVVDWLESIAKDEIGNFSDNIEFYAKSVYWENTLHILKQRQLSTYIGSSRPLVTELDPDAPIRQKLPLDDLDREDDARLLKYLFTLIRAGMTDEAQRLCKRCGQAWRAATLEGWKLYHDPNINGGNEVQPVEGNPYRCIWKICCWRMAEEEQFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDTLVEQEIRTSVVTTEEVEELPREYLETNWTTERVFEELQATDKKRVIEENQEHYRVIQKFIILGDVDGLMEEFSRWLSKDRSVLPGHLLRFMTHLILFFRTLGLQTKEEVSVEVLKTYIQRMISEKHTDLIAFYVSHLPPELAVVQYALFLEDVTESDQRHHCLELAKEAGLDVAAITKTVVENIRKKDAGDFSHHDHMLDTGTTEADRLKIDVIDWLVFDPAQRAEALKQSNAIMRKFLASKKHEAAKDVFVKIPQDSIAEIYNQWEEQGIEASLPAEDDNAIREHLCIRAYLEAHEIFNKWFQHMNSAPQKPPLLPQASFTEKVAHEHKEKKYEVALLWLTILIRIRAARAVTCKVDYGIWKSFLDGLTSDVKEKMYNVLLFVDGGWMVDVREDAEEDPERTHQMILLRKLCLPMMCFLLHTVLHSTGQYQECLRLADMVASERHKLYSVFSKEELRKFLQKLRESSLMLLDQDLDPLGYEIQS", "length": 937, "header": "tr|A0A8V0YN32-1|A0A8V0YN32_CHICK Isoform 1 of Nuclear pore complex protein OS=Gallus gallus OX=9031 GN=NUP107 PE=1 SV=1 CANONICAL=A0A8V0YN32-1" }, "locus": { "chromosome": "1", "start_pos": 35400095, "end_pos": 35375065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030190.1", "url": "https://www.ensembl.org/id/ENSGALT00010030190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017529.1", "url": "https://www.ensembl.org/id/ENSGALP00010017529.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", 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"ENSGALP00010017776.1", "url": "https://www.ensembl.org/id/ENSGALP00010017776.1" } ] } }, { "isoform_ac": "A0A8V0YAL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL2/entry", "sequence": { "sequence": "MADELDQLLDEVERRFCRMPDRGATGGGQNGDRERAAAEDRSAKTLMGAGSDEDDIDDIIDEICNDSSSFARTPLKLKSNSPSVTPGSNSTVVQAHRKRCCPVYLGGSSSPNGIGTNISKRTCDQLRCTACDFRVSLFNDYIWDQSCDYLFFRNNMPELSKLRAKMIKKKGSRAYACQCSWRSIDELTDLQADQQLRWVCGKHAE", "length": 205, "header": "tr|A0A8V0YAL2-1|A0A8V0YNS4_CHICK Computationally mapped isoform of Cilia- and flagella-associated protein 418 OS=Gallus gallus OX=9031 GN=C8orf37 PE=4 SV=1 CANONICAL=A0A8V0YNS4-1" }, "locus": { "chromosome": "2", "start_pos": 126082459, "end_pos": 126075875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030668.1", "url": "https://www.ensembl.org/id/ENSGALT00010030668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017782.1", "url": "https://www.ensembl.org/id/ENSGALP00010017782.1" } ] } }, { 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"isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 85, "start_aa": "Thr", "end_pos": 85, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr85", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420235", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS4" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS4" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 85 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNZ0-1", "uniprot_ac": "A0A8V0YNZ0", "uniprot_id": "A0A8V0YNZ0_CHICK", "mass": { "chemical_mass": 61315.0, "monoisotopic_mass": 61315.0 }, "refseq": {}, "gene_names": [ { "name": "TPH2", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ] } ], "protein_names": [ { "name": "Tryptophan 5-hydroxylase 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0/entry#names_and_taxonomy" } ] }, { "name": "1.14.16.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0/entry#names_and_taxonomy" } ] }, { "name": "Tryptophan 5-monooxygenase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0", "locus": { "chromosome": "1", "start_pos": 36696672, "end_pos": 36621601, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012834", "url": "https://www.ensembl.org/id/ENSGALG00010012834" } ] } } ], "crossref": [ { "id": "A0A8V0YNZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03346", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03346", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "408026", "url": "https://www.ncbi.nlm.nih.gov/gene/408026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VHFNPYT", "url": "https://omabrowser.org/oma/group/VHFNPYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAT6", "url": "https://www.orthodb.org/?gene=A0A8V0YAT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG39", "url": "https://www.orthodb.org/?gene=A0A8V0YG39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG49", "url": "https://www.orthodb.org/?gene=A0A8V0YG49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH44", "url": "https://www.orthodb.org/?gene=A0A8V0YH44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YNZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-209931", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209931", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16709", "url": "https://www.rhea-db.org/rhea/16709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTSMTSSLLLQKGSSLLADFWEMFCDEMTDSTPTFTRLPKHKQLAHILHCWTFPSTGICNAPSKP", "length": 538, "header": "tr|A0A8V0YNZ0-1|A0A8V0YNZ0_CHICK Isoform 1 of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT6/entry", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTEKFPKQVSVTPPSHSYSLQSSMGSV", "length": 500, "header": "tr|A0A8V0YAT6-1|A0A8V0YNZ0_CHICK Computationally mapped isoform of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "locus": { "chromosome": "1", "start_pos": 36694172, "end_pos": 36621634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030800.1", "url": "https://www.ensembl.org/id/ENSGALT00010030800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017868.1", "url": "https://www.ensembl.org/id/ENSGALP00010017868.1" } ] } }, { "isoform_ac": "A0A8V0YG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG39/entry", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRNLESTRCFCSCCG", "length": 445, "header": "tr|A0A8V0YG39-1|A0A8V0YNZ0_CHICK Computationally mapped isoform of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "locus": { "chromosome": "1", "start_pos": 36693973, "end_pos": 36621634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030792.1", "url": "https://www.ensembl.org/id/ENSGALT00010030792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017862.1", "url": "https://www.ensembl.org/id/ENSGALP00010017862.1" } ] } }, { "isoform_ac": "A0A8V0YG49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG49/entry", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRRNSQSRSLSLLPATLTHCSLQWEVFEIII", "length": 461, "header": "tr|A0A8V0YG49-1|A0A8V0YNZ0_CHICK Computationally mapped isoform of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "locus": { "chromosome": "1", "start_pos": 36694185, "end_pos": 36621634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030806.1", "url": "https://www.ensembl.org/id/ENSGALT00010030806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017872.1", "url": "https://www.ensembl.org/id/ENSGALP00010017872.1" } ] } }, { "isoform_ac": "A0A8V0YH44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH44/entry", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALSKMNRYLGI", "length": 457, "header": "tr|A0A8V0YH44-1|A0A8V0YNZ0_CHICK Computationally mapped isoform of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "locus": { "chromosome": "1", "start_pos": 36675157, "end_pos": 36621634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030777.1", "url": "https://www.ensembl.org/id/ENSGALT00010030777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017850.1", "url": "https://www.ensembl.org/id/ENSGALP00010017850.1" } ] } }, { "isoform_ac": "A0A8V0YNZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0/entry", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSALPEERPGGLTINRSSSGKNEDKKGNKGNGKGESVSEGGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRNSEVEIFVDCDCSKKEFNELIQLLKFQTNIVSLNPPENIWTDEEDLDCVPWFPRKISELDKCSQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMSYKYGQPIPRVEYTAEEIKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSIFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKAKVKTFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTSMTSSLLLQKGSSLLADFWEMFCDEMTDSTPTFTRLPKHKQLAHILHCWTFPSTGICNAPSKP", "length": 538, "header": "tr|A0A8V0YNZ0-1|A0A8V0YNZ0_CHICK Isoform 1 of Tryptophan 5-hydroxylase 2 OS=Gallus gallus OX=9031 GN=TPH2 PE=3 SV=1 CANONICAL=A0A8V0YNZ0-1" }, "locus": { "chromosome": "1", "start_pos": 36684390, "end_pos": 36621634, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030783.1", "url": "https://www.ensembl.org/id/ENSGALT00010030783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017854.1", "url": "https://www.ensembl.org/id/ENSGALP00010017854.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-209931", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209931", "resource": "Reactome", "description": "Serotonin and melatonin biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BGX6-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQLLTSLTLNKTNSGKNDDKKGNKGSSKNDTATESGKTAVVFSLKNEVGGLVKALKLFQEKHVNMIHIESRKSRRRSSEVEIFVDCECGKTEFNELIQSLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDRCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKHCGYREDNVPQLEDVAAFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 491 }, "evidence": [ { "id": "A0A8V0YNZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SH22-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQLLGSLTLNKSNSGKNDDKKGNKGSGKSDTATESGKTAVVFSLKNEVGGLVKALKLFQEKHVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQSLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDLAMGYKYGQPIPRVEYTEEETKTWGIVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSVFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 491 }, "evidence": [ { "id": "A0A8V0YNZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CGU9-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "Tph2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEEHQILGGLTQNKATASKSEDKRSGKDTSESSKTAVVFSLKNEVGGLVRALRLFQEKHVNMLHIESRRSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPDNIWTEEEELEDVPWFPRKISELDRCSHRVLMYGTELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQDAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 485 }, "evidence": [ { "id": "A0A8V0YNZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CGV2-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "Tph2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPAMMMFSSKYWARRGLSLDSAVPEDHQLLGSLTQNKAIKSEDKKSGKEPGKGDTTESSKTAVVFSLKNEVGGLVKALRLFQEKHVNMLHIESRRSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPESIWTEEEDLEDVPWFPRKISELDRCSHRVLMYGTELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNLPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYVRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKSFDPKTTCLQECLITTFQDAYFVSDSFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 488 }, "evidence": [ { "id": "A0A8V0YNZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWU9-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "TPH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI", "length": 490 }, "evidence": [ { "id": "A0A8V0YNZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tryptophan 5-monooxygenase activity", "id": "GO:0004510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen", "id": "GO:0016714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "serotonin biosynthetic process", "id": "GO:0042427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042427", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" }, { "name": "aromatic amino acid metabolic process", "id": "GO:0009072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" }, { "name": "phenol-containing compound biosynthetic process", "id": "GO:0046189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16709", "name": "", "equation": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A964-1", "P70080-1", "A0A8V0YNZ0-1" ], "evidence": [ { "id": "16709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16709" } ] }, { "id": "R-GGA-209828", "name": "Tryptophan is hydroxylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29500" ], "output_participant_list": [ "R-ALL-71112" ], "enzyme_list": [ "A0A8V1A964-1", "A0A8V0YNZ0-1" ], "evidence": [ { "id": "R-GGA-209828", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209828" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29500", "participant_name": "L-Trp [cytosol]", "crossref": [ { "id": "57912", "database": "ChEBI", "url": "" }, { "id": "ZINC000000083315", "database": "ZINC", "url": "" }, { "id": "C00078", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-71112", "participant_name": "4aOH-BH4 [cytosol]", "crossref": [ { "id": "ZINC000033913759", "database": "ZINC", "url": "" }, { "id": "HMDB0002281", "database": "HMDB Metabolite", "url": "" }, { "id": "15642", "database": "ChEBI", "url": "" }, { "id": "C06486", "database": "COMPOUND", "url": "" }, { "id": "ZINC000033913758", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YNZ0", "gene_name": "TPH2", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ] } ] }, { "uniprot_ac": "A0A8V1A964", "gene_name": "TPH1", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "A0A8V1A964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A964" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "A0A8V1A964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A964" } ] } ] }, { "uniprot_ac": "P70080", "gene_name": "TPH1", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "P70080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P70080" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "P70080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P70080" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" }, { "id": "PS51671", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51671" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACT", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 139, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" }, { "id": "PS51410", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51410" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Biopterin-dependent aromatic amino acid hydroxylase family profile", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 484, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "binding_site_uniprot": 317, "amino_acid": "His", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 317, "end_pos": 317, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "binding_site_uniprot": 322, "amino_acid": "His", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 322, "end_pos": 322, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" }, { "id": "A0A8V0YNZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ0" } ], "binding_site_uniprot": 362, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 362, "end_pos": 362, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.16.4", "ec_name": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "1.14.16.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4" }, { "id": "1.14.16.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.16.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 474, "end_pos": 476 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YP28-1", "uniprot_ac": "A0A8V0YP28", "uniprot_id": "A0A8V0YP28_CHICK", "mass": { "chemical_mass": 119499.0, "monoisotopic_mass": 119499.0 }, "refseq": { "ac": "XP_015138490", "name": "thyrotropin-releasing hormone-degrading ectoenzyme isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138490" }, "gene_names": [ { "name": "TRHDE", "type": "recommended", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ] }, { "name": "TRHDE", "type": "synonym", "evidence": [ { "id": "XP_015138490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138490" } ] } ], "protein_names": [ { "name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "type": "recommended", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.6", "type": "synonym", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry#names_and_taxonomy" } ] }, { "name": "Pyroglutamyl-peptidase II", "type": "synonym", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry#names_and_taxonomy" } ] }, { "name": "TRH-specific aminopeptidase", "type": "synonym", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry#names_and_taxonomy" } ] }, { "name": "Thyroliberinase", "type": "synonym", "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry#names_and_taxonomy" } ] }, { "name": "thyrotropin-releasing hormone-degrading ectoenzyme isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138490" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138490.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138490" } ] }, { "annotation": "Specific inactivation of TRH after its release.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28#function" }, { "database": "UniProtKB", "id": "ARBA00055732", "url": "https://www.uniprot.org/uniprotkb/ARBA00055732#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRHDE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28", "locus": { "chromosome": "1", "start_pos": 36959107, "end_pos": 36744594, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012849", "url": "https://www.ensembl.org/id/ENSGALG00010012849" } ] } } ], "crossref": [ { "id": "A0A8V0YP28", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP28", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09601", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09601", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427868", "url": "https://www.ncbi.nlm.nih.gov/gene/427868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427868", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427868", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKRLVMG", "url": "https://omabrowser.org/oma/group/HKRLVMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAV4", "url": "https://www.orthodb.org/?gene=A0A8V0YAV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP28", "url": "https://www.orthodb.org/?gene=A0A8V0YP28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11533:SF294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11533:SF294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALEEKREKRPPVTPMMIEEEAALRNGSRGLPPGPWAEAAGPRPRTTERHIAVHKRLVLGFAVSILALLAVTMVAVLLSVRFEECGAAADGPPRAANNGSLPGPAAGQPRGRAEPREEARGGEEAAERRQEEEEEEEEEWQRRRQLPPWARPRLPRHLRPLHYNLMLSAFMENFTFCGEVNVQLEVRNASRYIVLHAHRMHIEAVRVAEDKLAGAVRVARSFLYPQTQVLVVVLNRSLEVQRSYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYISLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAVCNFTYRETITKSGVVVRLYARPDAIRRGSGDYALNITRRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSVFVEQRILLDPSISSISYLLDVTMVIVHELCHQWFGDLVTPVWWEDVWLKEGFAHYFEFIGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLTSSHPVSQEVQQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQMGLQDYLTIHKYGNAARNDLWNTLSKALKRVGKSVNIQEVMDQWTLQMGYPVITILGNETTDNVIVISQERFVYDSDTKTKDSGLGDNSYLWQIPLTIAVGNTSHISSEAIIWVSNKSEHHRIPALEEASWLLGNINQTGYFRVNYDIRNWRLLINQLTRNHEVISVSDRAGLIDDAFNLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASQALYPLDKLLDRTENYNIFSEYILRQVASMYLKLGWPTNNLNKSLVQASYQHEELRREVIMLACSFGNKHCHQQAATLISDWISSNRNRIPLNVRDIVYCTGVSLMDEDVWEFIWMKFHSTLAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFREKWKILNARYGEALFMNSKLISGVTEFLNTEEELRELKNFIKSYEEGAAASFSRAVETVEANVRWQRLYKEELFQWLRKSLTH", "length": 1037, "header": "tr|A0A8V0YP28-1|A0A8V0YP28_CHICK Isoform 1 of Thyrotropin-releasing hormone-degrading ectoenzyme OS=Gallus gallus OX=9031 GN=TRHDE PE=3 SV=1 CANONICAL=A0A8V0YP28-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV4/entry", "sequence": { "sequence": "MLSAFMENFTFCGEVNVQLEVRNASRYIVLHAHRMHIEAVRVAEDKLAGAVRVARSFLYPQTQVLVVVLNRSLEVQRSYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYISLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAVCNFTYRETITKSGVVVRLYARPDAIRRGSGDYALNITRRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSVFVEQRILLDPSISSISYLLDVTMVIVHELCHQWFGDLVTPVWWEDVWLKEGFAHYFEFIGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLTSSHPVSQEVQQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQMGLQDYLTIHKYGNAARNDLWNTLSKALKRVGKSVNIQEVMDQWTLQMGYPVITILGNETTDNVIVISQERFVYDSDTKTKDSGLGDNSYLWQIPLTIAVGNTSHISSEAIIWVSNKSEHHRIPALEEASWLLGNINQTGYFRVNYDIRNWRLLINQLTRNHEVISVSDRAGLIDDAFNLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASQALYPLDKLLDRTENYNIFSEYILRQVASMYLKLGWPTNNLNKSLVQASYQHEELRREVIMLACSFGNKHCHQQAATLISDWISSNRNRPENQQCSGLHQKKHGQQVKGGDPATLLCGIEASREVQHPSVESSVQKRHGPIGVHPEEGHKNNPRNETPLLREQAEKAGAVQPGKEKAPGDLRVTFQYLKRSNRREGDRLFSRVCGDRTRGTGFKLTEGKFRLDIRKENSFTLRVVRHWNRSPREVVEVLIPGDFQI", "length": 862, "header": "tr|A0A8V0YAV4-1|A0A8V0YP28_CHICK Computationally mapped isoform of Thyrotropin-releasing hormone-degrading ectoenzyme OS=Gallus gallus OX=9031 GN=TRHDE PE=3 SV=1 CANONICAL=A0A8V0YP28-1" }, "locus": { "chromosome": "1", "start_pos": 36940434, "end_pos": 36745639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030831.1", "url": "https://www.ensembl.org/id/ENSGALT00010030831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017890.1", "url": "https://www.ensembl.org/id/ENSGALP00010017890.1" } ] } }, { "isoform_ac": "A0A8V0YP28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28/entry", "sequence": { "sequence": "MALEEKREKRPPVTPMMIEEEAALRNGSRGLPPGPWAEAAGPRPRTTERHIAVHKRLVLGFAVSILALLAVTMVAVLLSVRFEECGAAADGPPRAANNGSLPGPAAGQPRGRAEPREEARGGEEAAERRQEEEEEEEEEWQRRRQLPPWARPRLPRHLRPLHYNLMLSAFMENFTFCGEVNVQLEVRNASRYIVLHAHRMHIEAVRVAEDKLAGAVRVARSFLYPQTQVLVVVLNRSLEVQRSYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYISLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAVCNFTYRETITKSGVVVRLYARPDAIRRGSGDYALNITRRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSVFVEQRILLDPSISSISYLLDVTMVIVHELCHQWFGDLVTPVWWEDVWLKEGFAHYFEFIGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLTSSHPVSQEVQQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQMGLQDYLTIHKYGNAARNDLWNTLSKALKRVGKSVNIQEVMDQWTLQMGYPVITILGNETTDNVIVISQERFVYDSDTKTKDSGLGDNSYLWQIPLTIAVGNTSHISSEAIIWVSNKSEHHRIPALEEASWLLGNINQTGYFRVNYDIRNWRLLINQLTRNHEVISVSDRAGLIDDAFNLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASQALYPLDKLLDRTENYNIFSEYILRQVASMYLKLGWPTNNLNKSLVQASYQHEELRREVIMLACSFGNKHCHQQAATLISDWISSNRNRIPLNVRDIVYCTGVSLMDEDVWEFIWMKFHSTLAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFREKWKILNARYGEALFMNSKLISGVTEFLNTEEELRELKNFIKSYEEGAAASFSRAVETVEANVRWQRLYKEELFQWLRKSLTH", "length": 1037, "header": "tr|A0A8V0YP28-1|A0A8V0YP28_CHICK Isoform 1 of Thyrotropin-releasing hormone-degrading ectoenzyme OS=Gallus gallus OX=9031 GN=TRHDE PE=3 SV=1 CANONICAL=A0A8V0YP28-1" }, "locus": { "chromosome": "1", "start_pos": 36958828, "end_pos": 36745144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030846.1", "url": "https://www.ensembl.org/id/ENSGALT00010030846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017897.1", "url": "https://www.ensembl.org/id/ENSGALP00010017897.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427868", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427868", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AP33-1", "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "TRHDE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALDGERGEQEEEKKKKKKKKKRKKKKEEEGAKKSSSPFVATMGENDAALRAGGRGLSDPWADSVGVRPRTTERHITVHKRLVLAFAVSIVALLAVTMLAVLLSLRFDECGASIPPGADGGPAGFPARGGNESLPGSSRRDHHAGGDSSQPGAGREDTPETPSAQPPSEEEQEQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQVAEDRVAGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITIFGNTTAENRIIITQQHFIYDISAKAKPHELQNSSYLWQIPLTIVVGNRSHVSSEAIIWVSNKTEHHRITSLNKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMEKYNVFNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAISEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKSYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH", "length": 1066 }, "evidence": [ { "id": "A0A8V0YP28", "url": "https://omabrowser.org/oma/group/A0A8V0YP28/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BN23-1", "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "TRHDE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALDGERGKQEEEKKKKKKKKKRKKKEKGAQKSGSLFAATMGENDAALRAGGRGLSDPWADSAGVRPRTTERHITAHKRLVLAFAVSIVALLAVTMLAVLLSLRFDECGASVPSGADGGPAGFPARGGNESLPGPARRNHHAGGDPSQPGAGAEATPETPSAQPPSGEEREQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQVAEDRVAGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVLHGERRFLGITQFSPTHARKAFPCFDEPIYKATFKISIKHQASYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVAVRLYARPDAIRRGSGDYALHIAKRLIEFYEDYFNVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIITQQHFIYDISAKTKAHEPQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMEKYNIFNEYILKQVATTYIKLGWPKNSFNGSLVQASYQPEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAISEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKSYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH", "length": 1063 }, "evidence": [ { "id": "A0A8V0YP28", "url": "https://omabrowser.org/oma/group/A0A8V0YP28/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q10836-1", "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "Trhde", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALDGERGEQEEEKKKKKKKKKRKKKEEEGAEKSSSPFAATMGEDDAALRASGRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSIVALLAVTMLAVLLSLRFDECGASAAMPGTDGGLGGFPERGGNSSYPGSARRNHHAGEESSQREIGEVGTAGTPSAHPPSEEEQEQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACQNATRYVVLHASRVAVEKVQVAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNALIENELLGFFRSSYVIHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPSWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDKVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNMTAENRILITQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWILGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYSKLGWPKNNFNGSVVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKSYDGVASASFSRAVETVEANVRWKRLYQDELFQWLGKAMRH", "length": 1066 }, "evidence": [ { "id": "A0A8V0YP28", "url": "https://omabrowser.org/oma/group/A0A8V0YP28/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K093-1", "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "Trhde", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALDGERGEQEEEKKKKKKKKKRKKKEEEGAEKSSSPFAATMGEDDAALRASGRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSIVALLAVTMLAVLLSLRFDECGASAAMPGTDGGLGGFPERDSNSSFPGSARRNHHAGGESSQRESGEVGTPGTPSAQPPSEEEREQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQVAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNALIENELLGFFRSSYVIHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPAWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALRRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRILITQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRIAYLDRGSWILGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAALIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWPRNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKSYDGVASASFSRAVETVEANVRWKRFYQDELFQWLGKAMRH", "length": 1066 }, "evidence": [ { "id": "A0A8V0YP28", "url": "https://omabrowser.org/oma/group/A0A8V0YP28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKU6-1", "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "TRHDE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALDGELGEQEEEKKKKKKKKRKKKKEEEEEEEGAEKSSSPFAAAMGEDDAALRAGSRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSLVALLAVTMLAVLLSLRFDECGASATPGADGGPSGFPERGGNGSLPGSARRNHHAGGDSWQPEAGGVASPGTTSAQPPSEEEREPWEPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQLAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKNYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH", "length": 1069 }, "evidence": [ { "id": "A0A8V0YP28", "url": "https://omabrowser.org/oma/group/A0A8V0YP28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "pyroglutamyl-peptidase activity", "id": "GO:0016920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016920", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PF17900", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminopeptidase N-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 344, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PF11838", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ERAP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 691, "end_pos": 1014, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PF01433", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M1 membrane alanine aminopeptidase", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 604, "start_aa": "Tyr", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 288, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 288, "end_pos": 288, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 292, "amino_acid": "Phe", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 292, "end_pos": 292, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 311, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 311, "end_pos": 311, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 453, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 453, "end_pos": 453, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 457, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 457, "end_pos": 457, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP28" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 476, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 476, "end_pos": 476, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.6", "ec_name": "Release of the N-terminal pyroglutamyl group from pGlu-|-His-Xaa tripeptides and pGlu-|-His-Xaa-Gly tetrapeptides.", "evidence": [ { "id": "3.4.19.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.6" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 662, "end_pos": 664 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 697, "end_pos": 699 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 919, "end_pos": 921 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YP85-1", "uniprot_ac": "A0A8V0YP85", "uniprot_id": "A0A8V0YP85_CHICK", "mass": { "chemical_mass": 26906.0, "monoisotopic_mass": 26906.0 }, "refseq": { "ac": "XP_015154876", "name": "calcipressin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154876" }, "gene_names": [ { "name": "RCAN1", "type": "recommended", "evidence": [ { "id": "A0A8V0YP85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ] }, { "name": "RCAN1", "type": "synonym", "evidence": [ { "id": "XP_015154876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154876" } ] } ], "protein_names": [ { "name": "Calcipressin-1", "type": "recommended", "evidence": [ { "id": "A0A8V0YP85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85/entry#names_and_taxonomy" } ] }, { "name": "Regulator of calcineurin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YP85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85/entry#names_and_taxonomy" } ] }, { "name": "calcipressin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154876.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154876" } ] }, { "annotation": "Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP89#function" }, { "database": "UniProtKB", "id": "ARBA00024927", "url": "https://www.uniprot.org/uniprotkb/ARBA00024927#function" }, { "database": "UniProtKB", "id": "A0A8V0YB10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB10#function" }, { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85#function" }, { "database": "UniProtKB", "id": "E1BUP1", "url": "https://www.uniprot.org/uniprotkb/E1BUP1#function" }, { "database": "UniProtKB", "id": "A0A8V0YB06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB06#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RCAN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85", "locus": { "chromosome": "1", "start_pos": 106003299, "end_pos": 106045181, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012879", "url": "https://www.ensembl.org/id/ENSGALG00010012879" } ] } } ], "crossref": [ { "id": "A0A8V0YP85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016014", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12708", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12708", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418510", "url": "https://www.ncbi.nlm.nih.gov/gene/418510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418510", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIMQTRC", "url": "https://omabrowser.org/oma/group/RIMQTRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB06", "url": "https://www.orthodb.org/?gene=A0A8V0YB06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB10", "url": "https://www.orthodb.org/?gene=A0A8V0YB10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJE6", "url": "https://www.orthodb.org/?gene=A0A8V0YJE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP85", "url": "https://www.orthodb.org/?gene=A0A8V0YP85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP89", "url": "https://www.orthodb.org/?gene=A0A8V0YP89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BUP1", "url": "https://www.orthodb.org/?gene=E1BUP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10300:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10300:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUP1", "url": "https://www.uniprot.org/uniprotkb/E1BUP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGDGGGGRGPAGREEPPLGEAREEEEETEALPPPEAEPDWSFAGGEMEAVVLQDLPTATIACNLDPRVFQDGQCRAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 242, "header": "tr|A0A8V0YP85-1|A0A8V0YP85_CHICK Isoform 1 of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB06/entry", "sequence": { "sequence": "RDLWRPLSPTPSKAGSIQQVARESIQAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 191, "header": "tr|A0A8V0YB06-1|A0A8V0YP85_CHICK Computationally mapped isoform of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106020710, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030912.1", "url": "https://www.ensembl.org/id/ENSGALT00010030912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017951.1", "url": "https://www.ensembl.org/id/ENSGALP00010017951.1" } ] } }, { "isoform_ac": "A0A8V0YB10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB10/entry", "sequence": { "sequence": "HQNHKSPCADSLAVFPFQAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 183, "header": "tr|A0A8V0YB10-1|A0A8V0YP85_CHICK Computationally mapped isoform of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106015072, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030917.1", "url": "https://www.ensembl.org/id/ENSGALT00010030917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017956.1", "url": "https://www.ensembl.org/id/ENSGALP00010017956.1" } ] } }, { "isoform_ac": "A0A8V0YJE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE6/entry", "sequence": { "sequence": "MESGDGGGGRGPAGREEPPLGEAREEEEETEALPPPEAEPDWSFAGGEMEAVVLQDLPTATIACNLDPRVFQDGQCRTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 184, "header": "tr|A0A8V0YJE6-1|A0A8V0YP85_CHICK Computationally mapped isoform of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106044053, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030922.1", "url": "https://www.ensembl.org/id/ENSGALT00010030922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017959.1", "url": "https://www.ensembl.org/id/ENSGALP00010017959.1" } ] } }, { "isoform_ac": "A0A8V0YP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85/entry", "sequence": { "sequence": "MESGDGGGGRGPAGREEPPLGEAREEEEETEALPPPEAEPDWSFAGGEMEAVVLQDLPTATIACNLDPRVFQDGQCRAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 242, "header": "tr|A0A8V0YP85-1|A0A8V0YP85_CHICK Isoform 1 of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106044053, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030918.1", "url": "https://www.ensembl.org/id/ENSGALT00010030918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017957.1", "url": "https://www.ensembl.org/id/ENSGALP00010017957.1" } ] } }, { "isoform_ac": "A0A8V0YP89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP89/entry", "sequence": { "sequence": "FLPQLPFFCLFWEQFTAHQGPVSLSFTQAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 193, "header": "tr|A0A8V0YP89-1|A0A8V0YP89_CHICK Computationally mapped isoform of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106045179, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030925.1", "url": "https://www.ensembl.org/id/ENSGALT00010030925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017962.1", "url": "https://www.ensembl.org/id/ENSGALP00010017962.1" } ] } }, { "isoform_ac": "E1BUP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUP1/entry", "sequence": { "sequence": "MHFRNFNYSFSSLIACVADSDVFNQAETRAKFESLFRTYDRDITFQYFKSFKRVRINFSNPLSAADARVQLHKTEFLGKEIKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGDKYELHAATDTTPSVVVHVCESDQENDVEEEIKKPKPKIIQTRRPDYTPSHLS", "length": 194, "header": "tr|E1BUP1-1|A0A8V0YP85_CHICK Computationally mapped isoform of Calcipressin-1 OS=Gallus gallus OX=9031 GN=RCAN1 PE=3 SV=1 CANONICAL=A0A8V0YP85-1" }, "locus": { "chromosome": "1", "start_pos": 106012622, "end_pos": 106006130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030914.1", "url": "https://www.ensembl.org/id/ENSGALT00010030914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017953.1", "url": "https://www.ensembl.org/id/ENSGALP00010017953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SGX6-1", "protein_name": "Calcipressin-1", "gene_name": "RCAN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDGLAGSRLGAATEAAEARAQPGVTLRPFAPFSGAAEADEGSGDWSFIDCEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEDEDEMERMKRPKPKIIQTRRPEYTPIHLS", "length": 249 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35847-1", "protein_name": "Calcipressin-1", "gene_name": "RCAN1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHFRDFNYNFSSLIACVANGDVFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEEEEEMERMKRPKPKIIQTRRPEYTPIHLS", "length": 197 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53805-1", "protein_name": "Calcipressin-1", "gene_name": "RCAN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDGVAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAAEADEGGGDWSFIDCEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS", "length": 252 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBP4-1", "protein_name": "Calcipressin-1", "gene_name": "RCAN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHFRNFNYSFSSLIACVANSEIFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEEEDEMERMKRPKPKIIQTRRPEYTPIHLS", "length": 197 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6IN33-1", "protein_name": "Calcipressin-1", "gene_name": "Rcan1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHFRDFNYNFSSLIACVANGDVFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEEEEEEEEEMERMKRPKPKIIQTRRPEYTPIHLS", "length": 199 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHG6-1", "protein_name": "Calcipressin-1", "gene_name": "Rcan1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGVAGPRLGEVAEAVEARAPRRVTLRPFAPFSAAAEGDGGGGGDWSFIDCEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDTTFQYFKSFKRVRINFSNPLSAADARLRLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEEEEEEMERMKRPKPKIIQTRRPEYTPIHLS", "length": 251 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XZL8-1", "protein_name": "Protein sarah", "gene_name": "sra", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDAAKSNNNASADAPDPTTPDATGEADAANAATPTTPRGNHNNNNSANGRSKNKLKSTQNSSGGGSIDKLSPDQDIFINAADGLPNQHPSLPKEGDVDSDTEPEVDADSFDDLPTSIIVTNIHSEVFANPELKHAMEELFRTFSESATFQWLRSFRRLRVNYDNAIAAANARIKLHQYEFNKKTVITCYFAQPVTPVSNKNLQPPAPVKQFLISPPASPPAGWEPREEGEPLVNHDLLAALASLTPGESHELHPQSEDQPAIIVHTAMLAETGPGLQVKAPIVQTKCPERA", "length": 292 }, "evidence": [ { "id": "A0A8V0YP85", "url": "https://omabrowser.org/oma/group/A0A8V0YP85/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" }, { "name": "negative regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" }, { "name": "calcium-dependent protein serine/threonine phosphatase regulator activity", "id": "GO:0008597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008597", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQB5-1", "uniprot_ac": "A0A8V0YQB5", "uniprot_id": "A0A8V0YQB5_CHICK", "mass": { "chemical_mass": 38764.0, "monoisotopic_mass": 38764.0 }, "refseq": {}, "gene_names": [ { "name": "CD40", "type": "recommended", "evidence": [ { "id": "A0A8V0YQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5" } ] } ], "protein_names": [ { "name": "Tumor necrosis factor receptor superfamily member 5", "type": "recommended", "evidence": [ { "id": "A0A8V0YQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5/entry#names_and_taxonomy" } ] }, { "name": "B-cell surface antigen CD40", "type": "synonym", "evidence": [ { "id": "A0A8V0YQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5/entry#names_and_taxonomy" } ] }, { "name": "CD40L receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0YQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC43#function" }, { "database": "UniProtKB", "id": "ARBA00045871", "url": "https://www.uniprot.org/uniprotkb/ARBA00045871#function" }, { "database": "UniProtKB", "id": "A0A8V0YQB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5#function" }, { "database": "UniProtKB", "id": "A0A8V0YKH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQB5", "locus": { "chromosome": "20", "start_pos": 10967951, "end_pos": 10964213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013112", "url": "https://www.ensembl.org/id/ENSGALG00010013112" } ] } } ], "crossref": [ { "id": "A0A8V0YQB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC43", "url": "https://www.orthodb.org/?gene=A0A8V0YC43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKH8", "url": "https://www.orthodb.org/?gene=A0A8V0YKH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQB5", "url": "https://www.orthodb.org/?gene=A0A8V0YQB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46875:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46875:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5668541", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668541", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5676594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5676594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC43-1", "database": "UniProtKB", 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"tr|A0A8V0YQB5-1|A0A8V0YQB5_CHICK Isoform 1 of Tumor necrosis factor receptor superfamily member 5 OS=Gallus gallus OX=9031 GN=CD40 PE=4 SV=1 CANONICAL=A0A8V0YQB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC43/entry", "sequence": { "sequence": "MPGVTRTGRSGLCGVDCGQPGDAVNCSDKQYEHKGRCCNRCQPGKKLASECNDTEDSVCTPCENGQYQQSWTKERHCTPHEICEDNAGLIVKRHGNATHNTVCQCRAGMHCSDASCQTCVENEPCKQGFGFVAAMAEARMTSPCEPCAEGTFSNVSSKTEPCHFWTSCEEKGLVVKVKGTNTSDVICESSRRSSLSVLIPITAAVVTCLVGICIYCLVHTDLRRRGPKQAEAEAPRELVTQQPEEVDFPVQETLLGGQPVAQEDGKESRIAEQEQL", "length": 276, "header": "tr|A0A8V0YC43-1|A0A8V0YQB5_CHICK Computationally mapped isoform of Tumor necrosis factor receptor superfamily member 5 OS=Gallus gallus OX=9031 GN=CD40 PE=4 SV=1 CANONICAL=A0A8V0YQB5-1" }, "locus": { "chromosome": "20", "start_pos": 10967835, "end_pos": 10965016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031430.1", "url": 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22707", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22707", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424347", "url": "https://www.ncbi.nlm.nih.gov/gene/424347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VVLIKHW", "url": "https://omabrowser.org/oma/group/VVLIKHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGU7", "url": "https://www.orthodb.org/?gene=A0A8V0YGU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGW6", "url": "https://www.orthodb.org/?gene=A0A8V0YGW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLM5", "url": "https://www.orthodb.org/?gene=A0A8V0YLM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16183", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16183", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5625900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5625900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046800546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800546", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIYTVSVNKPYKAQCTATLQKTSSQNAFTSSKMLGQQLPSQVSGNNQDSLLSCSQNKSEEVNRTYVISACSNADDTSLTLRPPGRLTLRRRTRTSKNLASGGGQPDKNTPQGTESTQMEKRLTLQRRVKSGSVEKSTINGSTVPGAENSVFDAERKYKIALQPSISNNDTHYIKSSCKLAEGQQVINLNSKFHSKDVFGNVENDDCVHSKCRMDAADARFPKEVPVSEQLATSKYVNQVSGEQLHEKGDIKRMAGKQRLQQLKYNSLERPRTPTKASTEGFKLTPKNSTFQVKSSLSASSKQTADLPTVSEKKTSSSPGGRSAKADEDAESDSAEKDTFKVENSKVTVAVRVRPFSSREKNESLLPVVSMSGSETSVRNPSTNQLYNFSYDFSFWSFDECHPNFASQETIYKTLALPLLERAFEGYNTCLFAYGQTGSGKSYTMMGFDEDRGIIPRLCEDLFTRIAQTDQQQVLYHLEMSYFEVYNEKIHDLLVFKAESRQKKQPLRVREHPVLGPYVEDLTVNVVSSYSDIQSWLELGNKQRATAATVMNDKSSRSHSVFTLVMTQTKVKSVNEEQRDHRLTSHVNLIDLAGSECCSTAQTTGERLKEGVSINKSLLTLGRVISALSKLSRNGKKTFIPYRESVLTWLLKESLGGNSQTAMIATISPAASNAEETLSTLRYAKQACSIINMAKVNEDVNAKLIRELRAEIEKLKAAQKSAQNRDPEKYRHYLQEITSLRIKLHRQERDMTEMQRAWKAKLEQAEKRKLEDIKELQKAGIAFKMDNRLPNLVNLNEDPQLSEVLLYMIKEGETTVGRYTANSKHDIQLSGVLIADDHCVIENTTGQVSIIPRREAKTYVNGKCIVNPTVLHHGDRVILGGDHYFRFNHPVEVQKVKGLSCGTTLLHDGPKDFEFAKNELLIAQRAQLESEIEEARIKAKEEMMQSVQIAKEMVQQELTSQKEAYESKIKSLEAEVREESRKKQVQELNNQKAASKIQELEKAKQNLELELHFNRKRLEMEALATKQALEDHTIHHAKILKALEDEKQKIAEEIQTLQKNRASGNKTVNTPLNWNSLKLSVMIKEANTISNELGKNTVFNRHDKIDDKTGSVSSVQVQVRNVKLRIATFWSLEKFECKLAAMKELYESNDSNKAADVFYDPADEWEPDLSDASVSSLPRRRSRSFMKNKRISGCLSGIKLQPIQNTQASYISGTQNKSSIQPNFFDSLLPGICKESISSALDLLEQNHEGGKSIADHLLINLFTISSGVSAISKAYEQQEEECQKNFMSLDHDAQSYSIKITSAFDQLVVLIKTWLNNVQKCTGSMKTDEEIKQEVKNLGGYLQLLLQGCSSDISSMVTEAQSKVNEAVKQTMKCIGYLAVLTRTDISFFEENSISTISLQDFVRAVYDGVGSGLEVLMDTLQEKARMTQNELVKQYPQNEIQSQIKDSTVALARFLESNVSHCRKTGIQSQLPEEECLYQEIKRSTNIAAKYLELERCLSEVHQIVSSTLQGSFRNTSLLRSFAGEISIIAGYFNNYFSLLALSSANNPFQRTPMPFKNLDELDSLVDSLILSFELEQGQQKPKSQVACNGTTETEGRRVETGEAELSWKQKGVPKHTYKLHSPPALPGKLSPDRMIEWV", "length": 1641, "header": "tr|A0A8V0YLM5-1|A0A8V0YLM5_CHICK Isoform 1 of Kinesin-like protein KIF14 OS=Gallus gallus OX=9031 GN=KIF14 PE=3 SV=1 CANONICAL=A0A8V0YLM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ5/entry", "sequence": { "sequence": "MSIYTVSVNKPYKAQCTATLQKTSSQNAFTSSKMLGQQLPSQVSGNNQDSLLSCSQNKSEEVNRTYVISACSNADDTSLTLRPPGRLTLRRRTRTSKNLASGGGQPDKNTPQGTESTQMEKRLTLQRRVKSGSVEKSTINGSTVPGAENSVFDAERKYKIALQPSISNNDTHYIKSSCKLAEGQQVINLNSKFHSKDVFGNVENDDCVHSKCRMDAADARFPKEVPVSEQLATSKYVNQVSGEQLHEKGDIKRMAGKQRLQQLKYNSLERPRTPTKASTEGFKLTPKNSTFQVKSSLSASSKQTADLPTVSEKKTSSSPGGRSAKADEDAESDSAEKDTFKVENSKVTVAVRVRPFSSREKNESLLPVVSMSGSETSVRNPSTNQLYNFSYDFSFWSFDECHPNFASQETIYKTLALPLLERAFEGYNTCLFAYGQTGSGKSYTMMGFDEDRGIIPRLCEDLFTRIAQTDQQQVLYHLEMSYFEVYNEKIHDLLVFKAESRQKKQPLRVREHPVLGPYVEDLTVNVVSSYSDIQSWLELGNKQRATAATVMNDKSSRSHSVFTLVMTQTKVKSVNEEQRDHRLTSHVNLIDLAGSECCSTAQTTGERLKEGVSINKSLLTLGRVISALSKLSRNGKKTFIPYRESVLTWLLKESLGGNSQTAMIATISPAASNAEETLSTLRYAKQACSIINMAKVNEDVNAKLIRELRAEIEKLKAAQKSAQNRDPEKYRHYLQEITSLRIKLHRQERDMTEMQRAWKAKLEQAEKRKLEDIKELQKAGIAFKMDNRLPNLVNLNEDPQLSEVLLYMIKEGETTVGRYTANSKHDIQLSGVLIADDHCVIENTTGQVSIIPRREAKTYVNGKCIVNPTVLHHGDRVILGGDHYFRFNHPVEVQKVKGLSCGTTLLHDGPKDFEFAKNELLIAQRAQLESEIEEARIKAKEEMMQSVQIAKEMVQQELTSQKEAYESKIKSLEAEVREESRKKQVQELNNQKAASKIQELEKAKQNLELELHFNRKRLEMEALATKQALEDHTIHHAKILKALEDEKQKIAEEIQTLQKNRASGNKTVNTPLNWNSLKLSVMIKEANTISNELGKNTVFNRHDKIDDKTGSVSSVQVQVRNVKLRIATFWSLEKFECKLAAMKELYESNDSNKAADVFYDPADEWEPDLSDASVSSLPRRRSRSFMKNKRISGCLSGIKLQPIQNTQASYISGTQNKSSIQPNFFDSLLPGICKESISSALDLLEQNHEGGKSIADHLLINLFTISSGVSAISKAYEQQEEECQKNFMSLDHDAQSYSIKITSAFDQLVVLIKTWLNNVQKCTGSMKTDEEIKQEVKNLGGYLQLLLQGCSSDISSMVTEAQSKVNEAVKQTMKCIGYLAVLTRTDISFFEENSISTISLQDFVRAVYDGVGSGLEVLMDTLQEKARMTQNELVKQYPQNEIQSQIKDSTVALARFLESNVSHCRKTGIQSQLPEEECLYQEIKRSTNIAAKYLELERCLSEVHQIVSSTLQGSFRNTSLLRSFAGEISIIAGYFNNYFSLLALSSANNPFQRTPMPFKNLDELDSLVDSLILSFELEQGQQKPKSQVACNGTTETEGRRVETDEKNHPRRSVSSEYEYWITQEAFK", "length": 1627, "header": "tr|A0A8V0YDJ5-1|A0A8V0YLM5_CHICK Computationally mapped isoform of Kinesin-like protein KIF14 OS=Gallus gallus OX=9031 GN=KIF14 PE=3 SV=1 CANONICAL=A0A8V0YLM5-1" }, "locus": { "chromosome": "8", "start_pos": 1494337, "end_pos": 1467466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029292.1", "url": "https://www.ensembl.org/id/ENSGALT00010029292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017007.1", "url": "https://www.ensembl.org/id/ENSGALP00010017007.1" } ] } }, { "isoform_ac": "A0A8V0YGU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU7/entry", "sequence": { "sequence": "MSIYTVSVNKPYKAQCTATLQKTSSQNAFTSSKMLGQQLPSQVSGNNQDSLLSCSQNKSEEVNRTYVISACSNADDTSLTLRPPGRLTLRRRTRTSKNLASGGGQPDKNTPQGTESTQMEKRLTLQRRVKSGSVEKSTINGSTVPGAENSVFDAERKYKIALQPSISNNDTHYIKSSCKLAEGQQVINLNSKFHSKDVFGNVENDDCVHSKCRMDAADARFPKEVPVSEQLATSKYVNQVSGEQLHEKGDIKRMAGKQRLQQLKYNSLERPRTPTKASTEGFKLTPKNSTFQVKSSLSASSKQTADLPTVSEKKTSSSPGGRSAKADEDAESDSAEKDTFKVENSKVTVAVRVRPFSSREKNESLLPVVSMSGSETSVRNPSTNQLYNFSYDFSFWSFDECHPNFASQETIYKTLALPLLERAFEGYNTCLFAYGQTGSGKSYTMMGFDEDRGIIPRLCEDLFTRIAQTDQQQVLYHLEMSYFEVYNEKIHDLLVFKAESRQKKQPLRVREHPVLGPYVEDLTVNVVSSYSDIQSWLELGNKQRATAATVMNDKSSRSHSVFTLVMTQTKVKSVNEEQRDHRLTSHVNLIDLAGSECCSTAQTTGERLKEGVSINKSLLTLGRVISALSKLSRNGKKTFIPYRESVLTWLLKESLGGNSQTAMIATISPAASNAEETLSTLRYAKQACSIINMAKVNEDVNAKLIRELRAEIEKLKAAQKSAQNRDPEKYRHYLQEITSLRIKLHRQERDMTEMQRAWKAKLEQAEKRKLEDIKELQKAGIAFKMDNRLPNLVNLNEDPQLSEVLLYMIKEGETTVGRYTANSKHDIQLSGVLIADDHCVIENTTGQVSIIPRREAKTYVNGKCIVNPTVLHHGDRVILGGDHYFRFNHPVEVQKVKGLSCGTTLLHDGPKDFEFAKNELLIAQRAQLESEIEEARIKAKEEMMQSVQIAKEMVQQELTSQKEAYESKIKSLEAEVREESRKKQVQELNNQKAASKIQELEKAKQNLELELHFNRKRLEMEALATKQALEDHTIHHAKILKALEDEKQKIAEEIQTLQKNRASGNKTVNTPLNWNSLKLSVMIKEANTISNELGKNTVFNRHDKIDDKTGSVSSVQVQVRNVKLRIATFWSLEKFECKLAAMKELYESNDSNKAADVFYDPADEWEPDLSDASVSSLPRRRSRSFMKNKRISGCLSGIKLQPIQNTQASYISGTQNKSSIQPNFFDSLLPGICKESISSALDLLEQNHEGGKSIADHLLINLFTISSGVSAISKAYEQQEEECQKNFMSLDHDAQSYSIKITSAFDQLVVLIKTWLNNVQKCTGSMKTDEEIKQEVKNLGGYLQLLLQDFVRAVYDGVGSGLEVLMDTLQEKARMTQNELVKQYPQNEIQSQIKDSTVALARFLESNVSHCRKTGIQSQLPEEECLYQEIKRSTNIAAKYLELERCLSEVHQIVSSTLQGSFRNTSLLRSFAGEISIIAGYFNNYFSLLALSSANNPFQRTPMPFKNLDELDSLVDSLILSFELEQGQQKPKSQVACNGTTETEGRRVETGEAELSWKQKGVPKHTYKLHSPPALPGKLSPDRMIEWV", "length": 1588, "header": "tr|A0A8V0YGU7-1|A0A8V0YLM5_CHICK Computationally mapped isoform of Kinesin-like protein KIF14 OS=Gallus gallus OX=9031 GN=KIF14 PE=3 SV=1 CANONICAL=A0A8V0YLM5-1" }, "locus": { "chromosome": "8", "start_pos": 1489959, "end_pos": 1467466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029274.1", "url": "https://www.ensembl.org/id/ENSGALT00010029274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016991.1", "url": "https://www.ensembl.org/id/ENSGALP00010016991.1" } ] } }, { "isoform_ac": "A0A8V0YGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW6/entry", "sequence": { "sequence": "MSIYTVSVNKPYKAQCTATLQKTSSQNAFTSSKMLGQQLPSQVSGNNQDSLLSCSQNKSEEVNRTYVISACSNADDTSLTLRPPGRLTLRRRTRTSKNLASGGGQPDKNTPQGTESTQMEKRLTLQRRVKSGSVEKSTINGSTVPGAENSVFDAERKYKIALQPSISNNDTHYIKSSCKLAEGQQVINLNSKFHSKDVFGNVENDDCVHSKCRMDAADARFPKEVPVSEQLATSKYVNQVSGEQLHEKGDIKRMAGKQRLQQLKYNSLERPRTPTKASTEGFKLTPKNSTFQVKSSLSASSKQTADLPTVSEKKTSSSPGGRSAKADEDAESDSAEKDTFKVENSKVTVAVRVRPFSSREKNESLLPVVSMSGSETSVRNPSTNQLYNFSYDFSFWSFDECHPNFASQETIYKTLALPLLERAFEGYNTCLFAYGQTGSGKSYTMMGFDEDRGIIPRLCEDLFTRIAQTDQQQVLYHLEMSYFEVYNEKIHDLLVFKAESRQKKQPLRVREHPVLGPYVEDLTVNVVSSYSDIQSWLELGNKQRATAATVMNDKSSRSHSVFTLVMTQTKVKSVNEEQRDHRLTSHVNLIDLAGSECCSTAQTTGERLKEGVSINKSLLTLGRVISALSKLSRNGKKTFIPYRESVLTWLLKESLGGNSQTAMIATISPAASNAEETLSTLRYAKQACSIINMAKVNEDVNAKLIRELRAEIEKLKAAQKSAQNRDPEKYRHYLQEITSLRIKLHRQERDMTEMQRAWKAKLEQAEKRKLEDIKELQKAGIAFKMDNRLPNLVNLNEDPQLSEVLLYMIKEGETTVGRYTANSKHDIQLSGVLIADDHCVIENTTGQVSIIPRREAKTYVNGKCIVNPTVLHHGDRVILGGDHYFRFNHPVEVQKVKGLSCGTTLLHDGPKDFEFAKNELLIAQRAQLESEIEEARIKAKEEMMQSVQIAKEMVQQELTSQKEAYESKIKSLEAEVREESRKKQVQELNNQKAASKIQELEKAKQNLELELHFNRKRLEMEALATKQALEDHTIHHAKILKALEDEKQKIAEEIQTLQKNRASGNKTVNTPLNWNSLKLSVMIKEANTISNELGKNTVFNRHDKIDDKTGSVSSVQVQVRNVKLRIATFWSLEKFECKLAAMKELYESNDSNKAADVFYDPADEWEPDLSDASVSSLPRRRSRSFMKNKRISGCLSGIKLQPIQNTQASYISGTQNKSSIQPNFFDSLLPGICKESISSALDLLEQNHEGGKSIADHLLINLFTISSGVSAISKAYEQQEEECQKNFMSLDHDAQSYSIKITSAFDQLVVLIKTWLNNVQKCTGSMKTDEEIKQEVKNLGGYLQLLLQGCSSDISSMVTEAQSKVNEAVKQTMKCIGYLAVLTRTDISFFEENSISTISLQDFVRAVYDGVGSGLEVLMDTLQEKARMTQNELVKQYPQNEIQSQIKDSTVALARFLESNVSHCRKTGIQSQLPEEECLYQEIKRSTNIAAKYLELERCLSEVHQIVSSTLQGSFRNTSLLRSFAGEISIIAGYFNNYFSLLALSSANNPFQRTPMPFKNLDELDSLVDSLILSFELEQGQQKPKSQVACNGTTETEGRRVETGFCGCQPTNGI", "length": 1614, "header": "tr|A0A8V0YGW6-1|A0A8V0YLM5_CHICK Computationally mapped isoform of Kinesin-like protein KIF14 OS=Gallus gallus OX=9031 GN=KIF14 PE=3 SV=1 CANONICAL=A0A8V0YLM5-1" }, "locus": { "chromosome": "8", "start_pos": 1514104, "end_pos": 1467466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029297.1", "url": "https://www.ensembl.org/id/ENSGALT00010029297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017011.1", "url": "https://www.ensembl.org/id/ENSGALP00010017011.1" } ] } }, { "isoform_ac": "A0A8V0YLM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5/entry", "sequence": { "sequence": "MSIYTVSVNKPYKAQCTATLQKTSSQNAFTSSKMLGQQLPSQVSGNNQDSLLSCSQNKSEEVNRTYVISACSNADDTSLTLRPPGRLTLRRRTRTSKNLASGGGQPDKNTPQGTESTQMEKRLTLQRRVKSGSVEKSTINGSTVPGAENSVFDAERKYKIALQPSISNNDTHYIKSSCKLAEGQQVINLNSKFHSKDVFGNVENDDCVHSKCRMDAADARFPKEVPVSEQLATSKYVNQVSGEQLHEKGDIKRMAGKQRLQQLKYNSLERPRTPTKASTEGFKLTPKNSTFQVKSSLSASSKQTADLPTVSEKKTSSSPGGRSAKADEDAESDSAEKDTFKVENSKVTVAVRVRPFSSREKNESLLPVVSMSGSETSVRNPSTNQLYNFSYDFSFWSFDECHPNFASQETIYKTLALPLLERAFEGYNTCLFAYGQTGSGKSYTMMGFDEDRGIIPRLCEDLFTRIAQTDQQQVLYHLEMSYFEVYNEKIHDLLVFKAESRQKKQPLRVREHPVLGPYVEDLTVNVVSSYSDIQSWLELGNKQRATAATVMNDKSSRSHSVFTLVMTQTKVKSVNEEQRDHRLTSHVNLIDLAGSECCSTAQTTGERLKEGVSINKSLLTLGRVISALSKLSRNGKKTFIPYRESVLTWLLKESLGGNSQTAMIATISPAASNAEETLSTLRYAKQACSIINMAKVNEDVNAKLIRELRAEIEKLKAAQKSAQNRDPEKYRHYLQEITSLRIKLHRQERDMTEMQRAWKAKLEQAEKRKLEDIKELQKAGIAFKMDNRLPNLVNLNEDPQLSEVLLYMIKEGETTVGRYTANSKHDIQLSGVLIADDHCVIENTTGQVSIIPRREAKTYVNGKCIVNPTVLHHGDRVILGGDHYFRFNHPVEVQKVKGLSCGTTLLHDGPKDFEFAKNELLIAQRAQLESEIEEARIKAKEEMMQSVQIAKEMVQQELTSQKEAYESKIKSLEAEVREESRKKQVQELNNQKAASKIQELEKAKQNLELELHFNRKRLEMEALATKQALEDHTIHHAKILKALEDEKQKIAEEIQTLQKNRASGNKTVNTPLNWNSLKLSVMIKEANTISNELGKNTVFNRHDKIDDKTGSVSSVQVQVRNVKLRIATFWSLEKFECKLAAMKELYESNDSNKAADVFYDPADEWEPDLSDASVSSLPRRRSRSFMKNKRISGCLSGIKLQPIQNTQASYISGTQNKSSIQPNFFDSLLPGICKESISSALDLLEQNHEGGKSIADHLLINLFTISSGVSAISKAYEQQEEECQKNFMSLDHDAQSYSIKITSAFDQLVVLIKTWLNNVQKCTGSMKTDEEIKQEVKNLGGYLQLLLQGCSSDISSMVTEAQSKVNEAVKQTMKCIGYLAVLTRTDISFFEENSISTISLQDFVRAVYDGVGSGLEVLMDTLQEKARMTQNELVKQYPQNEIQSQIKDSTVALARFLESNVSHCRKTGIQSQLPEEECLYQEIKRSTNIAAKYLELERCLSEVHQIVSSTLQGSFRNTSLLRSFAGEISIIAGYFNNYFSLLALSSANNPFQRTPMPFKNLDELDSLVDSLILSFELEQGQQKPKSQVACNGTTETEGRRVETGEAELSWKQKGVPKHTYKLHSPPALPGKLSPDRMIEWV", "length": 1641, "header": "tr|A0A8V0YLM5-1|A0A8V0YLM5_CHICK Isoform 1 of Kinesin-like protein KIF14 OS=Gallus gallus OX=9031 GN=KIF14 PE=3 SV=1 CANONICAL=A0A8V0YLM5-1" }, "locus": { "chromosome": "8", "start_pos": 1489959, "end_pos": 1467466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029284.1", "url": "https://www.ensembl.org/id/ENSGALT00010029284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016999.1", "url": "https://www.ensembl.org/id/ENSGALP00010016999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5625900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5625900", "resource": "Reactome", "description": "RHO GTPases activate CIT" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZE01-1", "protein_name": "Kinesin-like protein KIF14", "gene_name": "Kif14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVHTSHSRHNIGSLEVSSSQKISASSGLVHSSRLELRLKSDMSECENHDPLANAGTKTIDINSTYVISACKKARETPATPDPGRLTLQRRTTWNKESSLLGSESGHPTGRTADTSLRLQRRPLARADYGEKWETSNPVGGNPGSKSASQKGRTEAKLVNNDSCALSSVVSEKDSNDTGLTKRKDPCPALSTSNEKVTVKNPNSRAPIGSQRQTEAMRSGHLVVQPVENKADIQVSGGGNSHHGNAGKGIAKHTSTFGSSETRTPAKCVSEHRSAPRHDLPPPKSPALSTQKNNGKDIAKHVSTFRNSSSETQTPAKCVLEHRWAPRHGLPPPKSPALSTLKNRIASPRVKPRPKSSLLANKSSQESTLPPEEKSTVQNTFTEPDSLKVENSQVTVAVRVRPFSKREKTEKASQVVFRNGEEITVEHPDMKQIYSFIYDVAFWSFDECHPGYANQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLNEEPGIIPRFCEDLFAQIAKKQASEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRVREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHSSGERLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYRESTLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYATQARLIVNVAKVNEDMNAKLIRELKAEIEKLKAAQKSSRNIDPERYRLCRQEISSLRMKLHQQERDMAEIQRVWKEKFEQAEKRKLQETKELQKAGVTFQMDNHLPNLVNLNEDPQLSEMLLYMVKEGITTVGKHTPNSSHDIQLSGVLIADDHCTIRSYGGTVSIVPAGEAKTYVNGMHISEPTVLHHGDRVVLGGDHYFRFNHPVEVQKGKKTSRNNLTSEGPKDFEFAKNELLAAQRSRLEAEIKDAQLKAKEEMMQGIQIAKEMAQQELSSQRAAYENKIRALEAELREESQRKRLEEINNQKASHKIEELEKAKQHLEQEVYVNKRRLEMETLATKQALEDHRIRHARILEALEREKQKIAEEVQILQENRGNRNKTFTIQPNWSSMKLSTMIQEANAISDKFKKHYVFGRHDASDKGRSDPSVRVRNLQLGISTFWNLEKFESKLAAMKDLYESNSGTRGEDVFCDPEDEWEPDITSTPVSSLSRRRSRSLMKNRRVSGCLHDIHPIQSMHPSHTSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFLGQSFDEEKTIADSLINNLLKLYNGVIAISKAHEEQDEESQDNVFSDRAAQALTIQVACAFEQLVVLFKHWLDDFPPCSGSARLEEELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKVTEIIQQAVGHVAQLAVLKGSKLCVLEDSNKVSSAQELMAALQDGTASGMRSLLDSGLETAQELRQDVSRQSAPEEVTRQMKANAVELVGSLENIFAEWRTKSFRTQVEEGSRQQGSKVLNLASEFLKLKSCLQQTIEMVVSALRGCPSDLRCLRSCTETICGLAHKLHGGFSALSDSAGSCGNEQPRAVWEELESLAKSLLLCFEHGERPSFLKPWESCTSNSTEEQRESDRADCSRSVPGRACEPHRDPTPAESSGDGTPSRIQWV", "length": 1672 }, "evidence": [ { "id": "A0A8V0YLM5", "url": "https://omabrowser.org/oma/group/A0A8V0YLM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "L0N7N1-1", "protein_name": "Kinesin-like protein KIF14", "gene_name": "Kif14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHTSHSRHNIGSLEVSSSQKISASSGLVHSSRLELHLKADMSECENHDPFVNAGSKTIDINSTYVISACKKTRETPVTSDPRRLSLQRRATCGDRESSLLGSELGNRRTADTSLRLQRRHGRADYVGKWETLNPVGGNPGSDSASQASRTEAKGVNNDTRVLSSVVSVKDSNDTGLTRCKDPGPPVGASNEKVTVKDTNSRAPVGSQRQTEAMRSGHLVVQLTESKSDTPVSGGRNSHRGNAGKDTAKQVGTFGSSDTRTPVKCVLEHRWTPRHDPPPPKSPALSTPKNNGKDIPKHGSTFRSASSESRTPVKCVPEHRWTPRHDLPPPKSPALSTLKNRIASPRVKPRPKSSLFANKRESSRESTLPPEENSLVQKTFTEPDSLKVENSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHRITSRINLVDLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVNIAKVNEDMNAKLIRELKAEIEKLKAAQRSNRNIDPERYRLCRQEITSLRMKLHQQERDMAEIQRVWKEKFEQAEKRKLQETKELQKAGVTFQMDNHLPNLVNLNEDPQLSEMLLYMVKEGVTTVGKHTPSSSHDIQLSGVLIADDHCTIRNFGGTVSIVPAGEAKTYVNGTHISEPTVLHHGDRVVLGGDHYFRFNHPVEVQKGKKLSSRNNLTTSEGPKDFEFAKNELLTAQRSRLEAEIKDAQLKAKEEMMQGIQIAKEMAQQELSSQKAVYERKIQALEAELREESQRKRLEELNNQKASHKIEELERAKQHLEQEVYVNKRRLEMETLATKQALEDHRIRHARILEALEIEKQKIAEEVQMLQENRGNRDKTFTIQPNWNSMKLSTMIQEANAISDKFKKCYIFGRHDASDKGRSDTSVRVRNLQLGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSRSLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFLGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKVMKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGPRRACEPHGDATPAVSSGDCTPNRIQWV", "length": 1674 }, "evidence": [ { "id": "A0A8V0YLM5", "url": "https://omabrowser.org/oma/group/A0A8V0YLM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15058-1", "protein_name": "Kinesin-like protein KIF14", "gene_name": "KIF14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKVRDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLTLQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV", "length": 1648 }, "evidence": [ { "id": "A0A8V0YLM5", "url": "https://omabrowser.org/oma/group/A0A8V0YLM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cerebellar Purkinje cell layer structural organization", "id": "GO:0021693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cerebellar granular layer structural organization", "id": "GO:0021685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "regulation of cell maturation", "id": "GO:1903429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903429", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "regulation of myelination", "id": "GO:0031641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031641", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "cell proliferation in forebrain", "id": "GO:0021846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021846", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM5" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", 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"PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 501, "end_pos": 667, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YLW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW0" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 434, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YLW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW0" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 55, "start_aa": "Met", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMK4-1", "uniprot_ac": "A0A8V0YMK4", "uniprot_id": "A0A8V0YMK4_CHICK", "mass": { "chemical_mass": 89414.0, "monoisotopic_mass": 89414.0 }, "refseq": {}, "gene_names": [ { "name": "LSS", "type": "recommended", "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ] } ], "protein_names": [ { "name": "Terpene cyclase/mutase family member", "type": "recommended", "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4/entry#names_and_taxonomy" } ] }, { "name": "5.4.99.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LSS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4", "locus": { "chromosome": "7", "start_pos": 6946058, "end_pos": 6956195, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013452", "url": "https://www.ensembl.org/id/ENSGALG00010013452" } ] } } ], "crossref": [ { "id": "A0A8V0YMK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEB4", "url": "https://www.orthodb.org/?gene=A0A8V0YEB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMK4", "url": "https://www.orthodb.org/?gene=A0A8V0YMK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11764", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11764", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11764:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11764:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13243", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13243", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9969896", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9969896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADGVVRRRGGPWRTAAATALPSWRLRCEGGRQRWCYLDDGVEDEEAAGGRRAQTALEAHSVGLDTDALLRTLPAAGTAREAARNGMRFYATLQAEDGHWAGDYGGPLFLLPGLLIVCHTARIPLPDGFRREMVRYLRSVQLPDGGWGLHVEDKSTVFGTALNYVALRILGLGPDDPDIVRARVNLHSKGGAVGIPSWGKFWLAVLNVYSWEGMNTLLPEMCCTSSRRHGTGAPGILLAQHLCVSPLALPVAHRSTLSIANRLLPTWFPAHPSRLWCHCRQVYLPMSYCYAKRLSAEEDELIRSLQQELYVQDYASIDWPAQRNNVAACDVYTPHSWLLGIAYAIMNVYEAHHSTYLRQRAITELYDHIKADDRFTKCISIGPISKTINMLVRWFVDGENSPAFQEHVSRIPDYLWLGLDGMKMQGTNGSQLWDTAFAVQAFLEAEAQKIPEFMSCLQNAHEFLRFTQIPENPPDYQKYYRHMNKGGFPFSTRDCGWIVADCTAEGLKSIMLLQEKCPFIANPVPAERLFDAVNVLLSMKNSDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFQDVYPEHRAPEIRETLQKGLDFCRKKQQADGSWEGSWGVCFTYGTWFGLEAFASMQHVYRDGVACREVARACQFLLSKQMTDGGWGEDFESCEQRTYVQSSTSQIHNTCWALLGLMAVRYPDTGVLERGIKLLIDKQLPNGDWPQENVAGVFNKSCAISYTAYRNVFPIWTLGRFSRLHPNSPLAEHLQSRPLAGVGKTPKTALSD", "length": 797, "header": "tr|A0A8V0YMK4-1|A0A8V0YMK4_CHICK Isoform 1 of Terpene cyclase/mutase family member OS=Gallus gallus OX=9031 GN=LSS PE=1 SV=1 CANONICAL=A0A8V0YMK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB4/entry", "sequence": { "sequence": "MAADGVVRRRGGPWRTAAATALPSWRLRCEGGRQRWCYLDDGVEDEEAAGGRRAQTALEAHSVGLDTDALLRTLPAAGTAREAARNGMRFYATLQAEDGHWAGDYGGPLFLLPGLLIVCHTARIPLPDGFRREMVRYLRSVQLPDGGWGLHVEDKSTVFGTALNYVALRILGLGPDDPDIVRARVNLHSKGGAVGIPSWGKFWLAVLNVYSWEGMNTLLPEMWLLPTWFPAHPSRLWCHCRQVYLPMSYCYAKRLSAEEDELIRSLQQLPLGVCSQLARLIACIVFCQELYVQDYASIDWPAQRNNVAACDVYTPHSWLLGIAYAIMNVYEAHHSTYLRQRAITELYDHIKADDRFTKCISIGPISKTINMLVRWFVDGENSPAFQEHVSRIPDYLWLGLDGMKMQGTNGSQLWDTAFAVQAFLEAEAQKIPEFMSCLQNAHEFLRFTQIPENPPDYQKYYRHMNKGGFPFSTRDCGWIVADCTAEGLKSIMLLQEKCPFIANPVPAERLFDAVNVLLSMKNSDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFQDVYPEHRAPEIRETLQKGLDFCRKKQQADGSWEGSWGVCFTYGTWFGLEAFASMQHVYRDGVACREVARACQFLLSKQMTDGGWGEDFESCEQRTYVQSSTSQIHNTCWALLGLMAVRYPDTGVLERGIKLLIDKQLPNGDWPQENVAGVFNKSCAISYTAYPLLLSTCNPDPWLGWGRPQRQHCLIEPMLWL", "length": 765, "header": "tr|A0A8V0YEB4-1|A0A8V0YMK4_CHICK Computationally mapped isoform of Terpene cyclase/mutase family member OS=Gallus gallus OX=9031 GN=LSS PE=1 SV=1 CANONICAL=A0A8V0YMK4-1" }, "locus": { "chromosome": "7", "start_pos": 6956106, "end_pos": 6946855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032390.1", "url": "https://www.ensembl.org/id/ENSGALT00010032390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019158.1", "url": "https://www.ensembl.org/id/ENSGALP00010019158.1" } ] } }, { "isoform_ac": "A0A8V0YMK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4/entry", "sequence": { "sequence": "MAADGVVRRRGGPWRTAAATALPSWRLRCEGGRQRWCYLDDGVEDEEAAGGRRAQTALEAHSVGLDTDALLRTLPAAGTAREAARNGMRFYATLQAEDGHWAGDYGGPLFLLPGLLIVCHTARIPLPDGFRREMVRYLRSVQLPDGGWGLHVEDKSTVFGTALNYVALRILGLGPDDPDIVRARVNLHSKGGAVGIPSWGKFWLAVLNVYSWEGMNTLLPEMCCTSSRRHGTGAPGILLAQHLCVSPLALPVAHRSTLSIANRLLPTWFPAHPSRLWCHCRQVYLPMSYCYAKRLSAEEDELIRSLQQELYVQDYASIDWPAQRNNVAACDVYTPHSWLLGIAYAIMNVYEAHHSTYLRQRAITELYDHIKADDRFTKCISIGPISKTINMLVRWFVDGENSPAFQEHVSRIPDYLWLGLDGMKMQGTNGSQLWDTAFAVQAFLEAEAQKIPEFMSCLQNAHEFLRFTQIPENPPDYQKYYRHMNKGGFPFSTRDCGWIVADCTAEGLKSIMLLQEKCPFIANPVPAERLFDAVNVLLSMKNSDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFQDVYPEHRAPEIRETLQKGLDFCRKKQQADGSWEGSWGVCFTYGTWFGLEAFASMQHVYRDGVACREVARACQFLLSKQMTDGGWGEDFESCEQRTYVQSSTSQIHNTCWALLGLMAVRYPDTGVLERGIKLLIDKQLPNGDWPQENVAGVFNKSCAISYTAYRNVFPIWTLGRFSRLHPNSPLAEHLQSRPLAGVGKTPKTALSD", "length": 797, "header": "tr|A0A8V0YMK4-1|A0A8V0YMK4_CHICK Isoform 1 of Terpene cyclase/mutase family member OS=Gallus gallus OX=9031 GN=LSS PE=1 SV=1 CANONICAL=A0A8V0YMK4-1" }, "locus": { "chromosome": "7", "start_pos": 6956106, "end_pos": 6946874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032394.1", "url": "https://www.ensembl.org/id/ENSGALT00010032394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019161.1", "url": "https://www.ensembl.org/id/ENSGALP00010019161.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-9969896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9969896", "resource": "Reactome", "description": "Lanosterol biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" }, { "name": "triterpenoid biosynthetic process", "id": "GO:0016104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidosqualene cyclase activity", "id": "GO:0031559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" }, { "name": "lanosterol synthase activity", "id": "GO:0000250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-191309" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMK4-1" ], "evidence": [ { "id": "R-GGA-191366", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191366" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-191309", "participant_name": "SQOX [cytosol]", "crossref": [ { "id": "C01054", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004095521", "database": "ZINC", "url": "" }, { "id": "HMDB0001188", "database": "HMDB Metabolite", "url": "" }, { "id": "6551", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "15441", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YMK4", "gene_name": "LSS", "activity": [ { "ec_number": "5.4.99.-", "activity": "", "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" }, { "id": "PF13243", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13243" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Squalene cyclase C-terminal", "eco_id": "ECO_0000259", "start_pos": 431, "end_pos": 767, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YMK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK4" }, { "id": "PF13249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Squalene cyclase N-terminal", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 223, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 429, "end_pos": 431 }, { "start_pos": 744, "end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMW4-1", "uniprot_ac": "A0A8V0YMW4", "uniprot_id": "A0A8V0YMW4_CHICK", "mass": { "chemical_mass": 40120.0, "monoisotopic_mass": 40120.0 }, "refseq": { "ac": "XP_004940851", "name": "palmitoyltransferase ZDHHC15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940851" }, "gene_names": [ { "name": "ZDHHC15", "type": "recommended", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ] }, { "name": "ZDHHC15", "type": "synonym", "evidence": [ { "id": "XP_004940851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940851" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940851.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZDHHC15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4", "locus": { "chromosome": "4", "start_pos": 12534951, "end_pos": 12560995, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013524", "url": "https://www.ensembl.org/id/ENSGALG00010013524" } ] } } ], "crossref": [ { "id": "A0A8V0YMW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007800", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007800", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422329", "url": "https://www.ncbi.nlm.nih.gov/gene/422329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422329", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEN0", "url": "https://www.orthodb.org/?gene=A0A8V0YEN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMW4", "url": "https://www.orthodb.org/?gene=A0A8V0YMW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NP33", "url": "https://www.orthodb.org/?gene=F1NP33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP33", "url": "https://www.uniprot.org/uniprotkb/F1NP33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP33-1", "url": "https://www.uniprot.org/uniprotkb/F1NP33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPFYRVPLLSVGEVAFLLYKQTCMKNVPRMCCAPVYVISSSEILGGKILRVTSVTLSNPAEKVAYLIIFHILFVLFVWTYWKSIFTLPVQPGKKYHMSYADKERYENEERPEVQRQILAEIARKLPVYTRTGSGGIRFCDRCQLIKPDRCHHCSVCAICVLKMDHHCPWVNNCIGFSNYKFFLLFLAYSLLYCLYIAATVFKYFIKYWTGELTNGRSKFHILFLLFLAVMFFVSLMFLFGYHCWLVSRNRSTLEAFSTPVFQNGPDKNGFNLGFVKNLQQVFGEEKKLWLLPIASSQGDGHFFPMRALCEAQNPLLSNEEQWEDDGIDEEPHDSGEAASLAIERET", "length": 348, "header": "tr|A0A8V0YMW4-1|A0A8V0YMW4_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0A8V0YMW4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN0/entry", "sequence": { "sequence": "MKNVPRMCCAPVYVISSSEILGGKILRVTSVTLSNPAEKVAYLIIFHILFVLFVWTYWKSIFTLPVQPGKKYHMSYADKERYENEERPEVQRQILAEIARKLPVYTRTGSGGIRFCDRCQLIKPDRCHHCSVCAICVLKMDHHCPWVNNCIGFSNYKFFLLFLAYSLLYCLYIAATVFKYFIKYWTGELTNGRSKFHILFLLFLAVMFFVSLMFLFGYHCWLVSRNRSTLEAFSTPVFQNGPDKNGFNLGFVKNLQQVFGEEKKLWLLPIASSQGDGHFFPMRALCEAQNPLLSNEEQWEDDGIDEEPHDSGEAASLAIERET", "length": 323, "header": "tr|A0A8V0YEN0-1|A0A8V0YMW4_CHICK Computationally mapped isoform of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0A8V0YMW4-1" }, "locus": { "chromosome": "4", "start_pos": 12559720, "end_pos": 12538578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032546.1", "url": "https://www.ensembl.org/id/ENSGALT00010032546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019278.1", "url": "https://www.ensembl.org/id/ENSGALP00010019278.1" } ] } }, { "isoform_ac": "A0A8V0YMW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4/entry", "sequence": { "sequence": "MSAPFYRVPLLSVGEVAFLLYKQTCMKNVPRMCCAPVYVISSSEILGGKILRVTSVTLSNPAEKVAYLIIFHILFVLFVWTYWKSIFTLPVQPGKKYHMSYADKERYENEERPEVQRQILAEIARKLPVYTRTGSGGIRFCDRCQLIKPDRCHHCSVCAICVLKMDHHCPWVNNCIGFSNYKFFLLFLAYSLLYCLYIAATVFKYFIKYWTGELTNGRSKFHILFLLFLAVMFFVSLMFLFGYHCWLVSRNRSTLEAFSTPVFQNGPDKNGFNLGFVKNLQQVFGEEKKLWLLPIASSQGDGHFFPMRALCEAQNPLLSNEEQWEDDGIDEEPHDSGEAASLAIERET", "length": 348, "header": "tr|A0A8V0YMW4-1|A0A8V0YMW4_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0A8V0YMW4-1" }, "locus": { "chromosome": "4", "start_pos": 12559795, "end_pos": 12538578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032542.1", "url": "https://www.ensembl.org/id/ENSGALT00010032542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019276.1", "url": "https://www.ensembl.org/id/ENSGALP00010019276.1" } ] } }, { "isoform_ac": "F1NP33-1", "url": "https://www.uniprot.org/uniprotkb/F1NP33/entry", "sequence": { "sequence": "MALSRGLRCCQRAFAWVPVLIITLVVLWSYYAYVCELCLMTLSNPAEKVAYLIIFHILFVLFVWTYWKSIFTLPVQPGKKYHMSYADKERYENEERPEVQRQILAEIARKLPVYTRTGSGGIRFCDRCQLIKPDRCHHCSVCAICVLKMDHHCPWVNNCIGFSNYKFFLLFLAYSLLYCLYIAATVFKYFIKYWTGELTNGRSKFHILFLLFLAVMFFVSLMFLFGYHCWLVSRNRSTLEAFSTPVFQNGPDKNGFNLGFVKNLQQVFGEEKKLWLLPIASSQGDGHFFPMRALCEAQNPLLSNEEQWEDDGIDEEPHDSGEAASLAIERET", "length": 332, "header": "tr|F1NP33-1|A0A8V0YMW4_CHICK Computationally mapped isoform of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC15 PE=3 SV=3 CANONICAL=A0A8V0YMW4-1" }, "locus": { "chromosome": "4", "start_pos": 12557607, "end_pos": 12538578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032538.1", "url": "https://www.ensembl.org/id/ENSGALT00010032538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019274.1", "url": "https://www.ensembl.org/id/ENSGALP00010019274.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422329", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" }, { "name": "synaptic vesicle maturation", "id": "GO:0016188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016188", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" }, { "name": "protein targeting to Golgi apparatus", "id": "GO:0140450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140450", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUB9-1", "A0A1D5NVK1-1", "A0A1D5PDT8-1", "A0A1D5PVV6-1", "A0A8V0XHB8-1", "A0A8V0XMA1-1", "A0A8V0XVP6-1", "A0A8V0YMW4-1", "A0A8V0YMN9-1", "A0A8V0YME7-1", "A0A8V0YPS8-1", "A0A8V0ZFK7-1", "A0A8V1ACZ6-1", "A0A8V0Z649-1", "A0A8V0ZZH0-1", "A0A8V0ZI56-1", "A0A8V1A9I9-1", "A0A8V1AH42-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVK1", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] } ] }, { "uniprot_ac": 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"synonym", "evidence": [ { "id": "XP_015155946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946" } ] }, { "name": "CHDZ", "type": "synonym", "evidence": [ { "id": "XP_015155946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946" } ] }, { "name": "LOC374195", "type": "synonym", "evidence": [ { "id": "XP_015155946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946" } ] } ], "protein_names": [ { "name": "DNA helicase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8/entry#names_and_taxonomy" } ] }, { "name": "chromodomain-helicase-DNA-binding protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015155946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHD1W", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8", "locus": {} } ], "crossref": [ { "id": "cd18661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374195", "url": "https://www.ncbi.nlm.nih.gov/gene/374195", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374195", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEN5", "url": "https://www.orthodb.org/?gene=A0A8V0YEN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEP1", "url": "https://www.orthodb.org/?gene=A0A8V0YEP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEP8", "url": "https://www.orthodb.org/?gene=A0A8V0YEP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFS4", "url": "https://www.orthodb.org/?gene=A0A8V0YFS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHW3", "url": "https://www.orthodb.org/?gene=A0A8V0YHW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMM9", "url": "https://www.orthodb.org/?gene=A0A8V0YMM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMN8", "url": "https://www.orthodb.org/?gene=A0A8V0YMN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEDEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1777, "header": "tr|A0A8V0YMN8-1|A0A8V0YMN8_CHICK Isoform 1 of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEN5/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSEDLLSSEDSTDGSSSETKKKKRRECFGILSEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEDEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1761, "header": "tr|A0A8V0YEN5-1|A0A8V0YMN8_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029843.1", "url": "https://www.ensembl.org/id/ENSGALT00010029843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017378.1", "url": "https://www.ensembl.org/id/ENSGALP00010017378.1" } ] } }, { "isoform_ac": "A0A8V0YEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP1/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1691, "header": "tr|A0A8V0YEP1-1|A0A8V0YMN8_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029856.1", "url": "https://www.ensembl.org/id/ENSGALT00010029856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017385.1", "url": "https://www.ensembl.org/id/ENSGALP00010017385.1" } ] } }, { "isoform_ac": "A0A8V0YEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP8/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEDEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1718, "header": "tr|A0A8V0YEP8-1|A0A8V0YMN8_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029865.1", "url": "https://www.ensembl.org/id/ENSGALT00010029865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017390.1", "url": "https://www.ensembl.org/id/ENSGALP00010017390.1" } ] } }, { "isoform_ac": "A0A8V0YFS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS4/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKNSCTHQTTSSIMAA", "length": 1281, "header": "tr|A0A8V0YFS4-1|A0A8V0YMN8_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5533893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029838.1", "url": "https://www.ensembl.org/id/ENSGALT00010029838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017376.1", "url": "https://www.ensembl.org/id/ENSGALP00010017376.1" } ] } }, { "isoform_ac": "A0A8V0YHW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW3/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGADEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1736, "header": "tr|A0A8V0YHW3-1|A0A8V0YMN8_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029851.1", "url": "https://www.ensembl.org/id/ENSGALT00010029851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017382.1", "url": "https://www.ensembl.org/id/ENSGALP00010017382.1" } ] } }, { "isoform_ac": "A0A8V0YMM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM9/entry", "sequence": { "sequence": "KVDGSESSPSILSLQRSVALKKQQQQMTSSSGSGSEELLFLSFNMYSEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEDEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1693, "header": "tr|A0A8V0YMM9-1|A0A8V0YMM9_CHICK Computationally mapped isoform of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5602026, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029830.1", "url": "https://www.ensembl.org/id/ENSGALT00010029830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017370.1", "url": "https://www.ensembl.org/id/ENSGALP00010017370.1" } ] } }, { "isoform_ac": "A0A8V0YMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8/entry", "sequence": { "sequence": "MNGPSDEESIRNSSGESSQSDDDSGSTSASGSGSSSGSGSDGSSSQSGSSDSESASESGSQSELESDASREKKQVQAKPPKVDGSERSVALKKQQQQMTSSSGSGSEEDLLSSEDSTDGSSSETKKKKRRDEDWQVSRSGSISGTSSDSESEEDREKNSCEESESDYEPKNKVKSQKPPRRIKPKSCKKGTGQKKRQFDSSDGDDDYDKRGSRRQATVNVSYKEAEETKTDSDELLEVCGEDVPQPEEDEFETIEKFMDSRIGRKGATGAATTIYAIEADGDPNTGFEKSKEPGEIQYLIKWKGWSHIHNTWESEETLKQQNVKGMKKLDNYKKKCQETKRWLKNASPEDVEYYNCQQEFTDDLHKQYQVVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQACIDEYFSRNQSKTTPFKDCKILKQRPRFVALKKQPSYIGGRDCLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHELYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWVFIGIDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREFGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEEEPQEMDIDEILKRAETRENESGPLTVGDELLSQFKVANFSNMDEDDIELEPEQNLRNWEEIIPEVQWRRIEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRCSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALNDNDFGQGRTGGRFGKVKGPTFRIAGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPYHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRSKKNKATKAAKIKEIKNDSSSPPSEKSDDDNEDEIVSVKHPHKKIKAEKENEEKDEPDIGIKKEAGEKRETKEKENKRDLKREKKEKEDKKELKYIKEKRENKVKEFIQKVKEVKEEKVNEIKSEYKEKNKKVPLLDIPVHITAISEPVPISDESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHSDQNIAANVNTQVIRNPNVESLKENTNHDDSIRDSYSSDRHLCQYHDHHKDRYQGDTYKKSDSRKRPYSDFSNGKDHRDWDHYKDSRYCSDSKHRKLDGHRSRDHKSNLEGSLKDSRPHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGSRSPLDQRSPYGSRSPFEHSSDHKSTPEHTWSGWKT", "length": 1777, "header": "tr|A0A8V0YMN8-1|A0A8V0YMN8_CHICK Isoform 1 of DNA helicase OS=Gallus gallus OX=9031 GN=CHD1W PE=4 SV=1 CANONICAL=A0A8V0YMN8-1" }, "locus": { "chromosome": "W", "start_pos": 5637544, "end_pos": 5525040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029847.1", "url": "https://www.ensembl.org/id/ENSGALT00010029847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017380.1", "url": "https://www.ensembl.org/id/ENSGALP00010017380.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374195", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1334, "end_pos": 1336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 984, "end_pos": 986, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", 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} ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of 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"id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": 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"A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": 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"activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] } ] }, { "uniprot_ac": "O12944", "gene_name": "RAD54L", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O12944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12944" } ] } ] }, { "uniprot_ac": "O93257", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] } ] }, { "uniprot_ac": "O93295", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] } ] }, { "uniprot_ac": "P08023", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08023" } ] } ] }, { "uniprot_ac": "P08110", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08110", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68034" } ] } ] }, { "uniprot_ac": "P68139", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68139" } ] } ] }, { "uniprot_ac": "P79784", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "P79784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79784" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "P79784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79784" } ] } ] }, { "uniprot_ac": "Q06A37", "gene_name": "CHD7", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": 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] } ] }, { "uniprot_ac": "Q5ZHZ0", "gene_name": "DDX39B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] } ] }, { "uniprot_ac": "Q5ZI74", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] } ] }, { "uniprot_ac": "Q5ZIW1", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] } ] }, { "uniprot_ac": "Q5ZJ54", "gene_name": "CCT6", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ54" } ] } ] }, { "uniprot_ac": "Q5ZJF6", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] } ] }, { "uniprot_ac": "Q5ZJK8", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK8" } ] } ] }, { "uniprot_ac": "Q5ZJT0", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJT0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJT0" } ] } ] }, { "uniprot_ac": "Q5ZKB7", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "Q5ZKB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB7" } ] } ] }, { "uniprot_ac": "Q5ZKB9", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZKB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZKB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB9" } ] } ] }, { "uniprot_ac": "Q5ZKG3", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "Q5ZKG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG3" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q5ZKG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG3" } ] } ] }, { "uniprot_ac": "Q5ZKK7", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK7" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q5ZKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK7" } ] } ] }, { "uniprot_ac": "Q5ZLN8", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZLN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZLN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN8" } ] } ] }, { "uniprot_ac": "Q5ZM36", "gene_name": "EIF4A3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZM36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM36" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZM36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM36" } ] } ] }, { "uniprot_ac": "Q5ZM73", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5ZM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM73" } ] } ] }, { "uniprot_ac": "Q5ZM83", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5ZM83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM83" } ] } ] }, { "uniprot_ac": "Q5ZM98", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM98" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q5ZM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM98" } ] } ] }, { "uniprot_ac": "Q5ZMN2", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMN2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q5ZMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMN2" } ] } ] }, { "uniprot_ac": "Q5ZMQ2", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q5ZMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ2" } ] } ] }, { "uniprot_ac": "Q6EE31", "gene_name": "CCT8", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q6EE31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6EE31" } ] } ] }, { "uniprot_ac": "Q8JFP1", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q8JFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JFP1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q8JFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JFP1" } ] } ] }, { "uniprot_ac": "Q90593", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] } ] }, { "uniprot_ac": "Q90WU3", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] } ] }, { "uniprot_ac": "Q92058", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] } ] }, { "uniprot_ac": "Q9DG67", "gene_name": "RAD54B", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q9DG67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DG67" } ] } ] }, { "uniprot_ac": "Q9I920", "gene_name": "BLM", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 344, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 473, "end_pos": 643, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN8" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 772, "end_pos": 923, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 12, "end_pos": 14 }, { "start_pos": 1334, "end_pos": 1336 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 984, "end_pos": 986 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN78-1", "uniprot_ac": "A0A8V0YN78", "uniprot_id": "A0A8V0YN78_CHICK", "mass": { "chemical_mass": 38131.0, "monoisotopic_mass": 38131.0 }, "refseq": { "ac": "NP_001264922", "name": "secretory carrier-associated membrane protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264922" }, "gene_names": [ { "name": "SCAMP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YN78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ] }, { "name": "SCAMP1", "type": "synonym", "evidence": [ { "id": "NP_001264922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264922" } ] } ], "protein_names": [ { "name": "Secretory carrier-associated membrane protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YN78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78/entry#names_and_taxonomy" } ] }, { "name": "Secretory carrier membrane protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YN78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78/entry#names_and_taxonomy" } ] }, { "name": "secretory carrier-associated membrane protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264922" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR353663.1, SRR13267659.250561.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. On May 5, 2013 this sequence version replaced XP_414682.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001264922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCAMP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78", "locus": { "chromosome": "Z", "start_pos": 23259961, "end_pos": 23299225, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012667", "url": "https://www.ensembl.org/id/ENSGALG00010012667" } ] } } ], "crossref": [ { "id": "A0A8V0YN78", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN78", "database": "AlphaFoldDB", "categories": [] }, { "id": "416368", "url": "https://www.ncbi.nlm.nih.gov/gene/416368", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416368", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416368", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMVACIF", "url": "https://omabrowser.org/oma/group/NMVACIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF89", "url": "https://www.orthodb.org/?gene=A0A8V0YF89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIE2", "url": "https://www.orthodb.org/?gene=A0A8V0YIE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN78", "url": "https://www.orthodb.org/?gene=A0A8V0YN78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTAPPGNVKMPNVPSTQPAIMKPTEEPPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQSLNQQGGRKNNWPPLPENFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHTVTLFLNIFGCLAWFYVDATRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFQRWGNCGWISSLTGLNKSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNRM", "length": 339, "header": "tr|A0A8V0YN78-1|A0A8V0YN78_CHICK Isoform 1 of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP1 PE=1 SV=1 CANONICAL=A0A8V0YN78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF89/entry", "sequence": { "sequence": "MPRMTSNLPRAAHGLSQPHHLPAAQGPPLSPLAVPSRPATPFPGRPFWEAGARRLVGAEGAGSGRAAGAAGVRAGGIPRAGECGAPQGESRRHHHPEIAAPAMSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTAPPGNVKMPNVPSTQPAIMKPTEEPPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQSLNQQGGRKNNWPPLPENFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHTVTLFLNIFGCLAWFYVDATRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFQRWGNCGWISSLTGLNKSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNRM", "length": 441, "header": "tr|A0A8V0YF89-1|A0A8V0YN78_CHICK Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP1 PE=1 SV=1 CANONICAL=A0A8V0YN78-1" }, "locus": { "chromosome": "Z", "start_pos": 23299026, "end_pos": 23262836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030303.1", "url": "https://www.ensembl.org/id/ENSGALT00010030303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017577.1", "url": "https://www.ensembl.org/id/ENSGALP00010017577.1" } ] } }, { "isoform_ac": "A0A8V0YIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE2/entry", "sequence": { "sequence": "MMSGLQEEDPSVTQVTRNVPPGLDEYNPFSDSRTAPPGNVKMPNVPSTQPAIMKPTEEPPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQSLNQQGGRKNNWPPLPENFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHTVTLFLNIFGCLAWFYVDATRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFQRWGNCGWISSLTGLNKSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNRM", "length": 328, "header": "tr|A0A8V0YIE2-1|A0A8V0YN78_CHICK Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP1 PE=1 SV=1 CANONICAL=A0A8V0YN78-1" }, "locus": { "chromosome": "Z", "start_pos": 23285846, "end_pos": 23262836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030297.1", "url": "https://www.ensembl.org/id/ENSGALT00010030297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017571.1", "url": "https://www.ensembl.org/id/ENSGALP00010017571.1" } ] } }, { "isoform_ac": "A0A8V0YN78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78/entry", "sequence": { "sequence": "MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTAPPGNVKMPNVPSTQPAIMKPTEEPPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQSLNQQGGRKNNWPPLPENFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHTVTLFLNIFGCLAWFYVDATRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFQRWGNCGWISSLTGLNKSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNRM", "length": 339, "header": "tr|A0A8V0YN78-1|A0A8V0YN78_CHICK Isoform 1 of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP1 PE=1 SV=1 CANONICAL=A0A8V0YN78-1" }, "locus": { "chromosome": "Z", "start_pos": 23298720, "end_pos": 23262836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030300.1", "url": "https://www.ensembl.org/id/ENSGALT00010030300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017574.1", "url": "https://www.ensembl.org/id/ENSGALP00010017574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416368", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416368", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "O15126-1", "protein_name": "Secretory carrier-associated membrane protein 1", "gene_name": "SCAMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGGVKMPNVPNTQPAIMKPTEEHPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNQNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAASSAAQNAFKGNQI", "length": 338 }, "evidence": [ { "id": "A0A8V0YN78", "url": "https://omabrowser.org/oma/group/A0A8V0YN78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O77735-1", "protein_name": "Secretory carrier-associated membrane protein 1", "gene_name": "SCAMP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGNVKMPNVPSTQPAIMKPTEEHPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPGNFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHAVTLFLNIFGCLAWFCVDPSRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNQSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNQI", "length": 338 }, "evidence": [ { "id": "A0A8V0YN78", "url": "https://omabrowser.org/oma/group/A0A8V0YN78/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8K021-1", "protein_name": "Secretory carrier-associated membrane protein 1", "gene_name": "Scamp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGSVKMPNVPNTQPAIMKPTEEHPAYTQITKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNQM", "length": 338 }, "evidence": [ { "id": "A0A8V0YN78", "url": "https://omabrowser.org/oma/group/A0A8V0YN78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXV6-1", "protein_name": "Secretory carrier-associated membrane protein", "gene_name": "Scamp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGSGLDENPFGEPNLDNPFADPAIQQARRLQSGAALVSLEDYNPFEEQAKPQLQINSTNTAAVVQPLSQNIPPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQLQGNVPQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLILLFHAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMGYCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTTEFLRNQHVQEAASSAVNTAINSQFNNSRY", "length": 343 }, "evidence": [ { "id": "A0A8V0YN78", "url": "https://omabrowser.org/oma/group/A0A8V0YN78/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" }, { "name": "zymogen granule membrane", "id": "GO:0042589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0YM70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70", "locus": { "chromosome": "Z", "start_pos": 53917320, "end_pos": 54028873, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012353", "url": "https://www.ensembl.org/id/ENSGALG00010012353" } ] } } ], "crossref": [ { "id": "A0A8V0YM70", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM70", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16024", "url": 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] }, { "id": "gga:427290", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427290", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RVKFGHD", "url": "https://omabrowser.org/oma/group/RVKFGHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFB4", "url": "https://www.orthodb.org/?gene=A0A8V0YFB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHE1", "url": "https://www.orthodb.org/?gene=A0A8V0YHE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHF9", "url": "https://www.orthodb.org/?gene=A0A8V0YHF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM70", "url": "https://www.orthodb.org/?gene=A0A8V0YM70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM78", "url": "https://www.orthodb.org/?gene=A0A8V0YM78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM83", "url": "https://www.orthodb.org/?gene=A0A8V0YM83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23072:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23072:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSTSGSGLERCWPLANRRAGRAGAVAADWPEAGRGGAEDAGSGPGAGRRVGRMRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTSSEHKSELSVLAAISLVMIFVLVQRRCSLVSKIAMALGLLGVYSYRAAIGNVIFPWQHDSKDISKGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSRNSAAVGHGCFCYALMRSIPVAIYIVLVTGLRYHLFIWSVFSPKLLYEGMHVFITAAICLFFTAMDQNHSQKVQG", "length": 1045, "header": "tr|A0A8V0YM70-1|A0A8V0YM70_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB4/entry", "sequence": { "sequence": "MMDGEGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTSSEHKSELSVLAAISLVMIFVLVQRRCSLVSKIAMALGLLGVYSYRAAIGNVIFPWQHDSKDISKGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSRNSAAVGHGCFCYALMRSIPVAIYIVLVTGLRYHLFIWSVFSPKLLYEGMHVFITAAICLFFTAMDQNHSQKVQG", "length": 941, "header": "tr|A0A8V0YFB4-1|A0A8V0YM70_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028320, "end_pos": 53918510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029579.1", "url": "https://www.ensembl.org/id/ENSGALT00010029579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017202.1", "url": "https://www.ensembl.org/id/ENSGALP00010017202.1" } ] } }, { "isoform_ac": "A0A8V0YHE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE1/entry", "sequence": { "sequence": "MRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTETVFCQQCFSLLYFQAPKNGCSLYLLLRS", "length": 222, "header": "tr|A0A8V0YHE1-1|A0A8V0YM70_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028684, "end_pos": 54021785, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029567.1", "url": "https://www.ensembl.org/id/ENSGALT00010029567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017193.1", "url": "https://www.ensembl.org/id/ENSGALP00010017193.1" } ] } }, { "isoform_ac": "A0A8V0YHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF9/entry", "sequence": { "sequence": "MRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTSSEHKSELSVLAAISLVMIFVLVQRRCSLVSKIAMALGLLGVYSYRAAIGNVIFPWQHDSKDISKGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSRQTLWKGAGRPTRDEAVLKLLNGVFKN", "length": 943, "header": "tr|A0A8V0YHF9-1|A0A8V0YM70_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028684, "end_pos": 53919026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029587.1", "url": "https://www.ensembl.org/id/ENSGALT00010029587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017208.1", "url": "https://www.ensembl.org/id/ENSGALP00010017208.1" } ] } }, { "isoform_ac": "A0A8V0YM70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70/entry", "sequence": { "sequence": "MRGSTSGSGLERCWPLANRRAGRAGAVAADWPEAGRGGAEDAGSGPGAGRRVGRMRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTSSEHKSELSVLAAISLVMIFVLVQRRCSLVSKIAMALGLLGVYSYRAAIGNVIFPWQHDSKDISKGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSRNSAAVGHGCFCYALMRSIPVAIYIVLVTGLRYHLFIWSVFSPKLLYEGMHVFITAAICLFFTAMDQNHSQKVQG", "length": 1045, "header": "tr|A0A8V0YM70-1|A0A8V0YM70_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028846, "end_pos": 53918510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029572.1", "url": "https://www.ensembl.org/id/ENSGALT00010029572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017196.1", "url": "https://www.ensembl.org/id/ENSGALP00010017196.1" } ] } }, { "isoform_ac": "A0A8V0YM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM78/entry", "sequence": { "sequence": "MRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTSSEHKSELSVLAAISLVMIFVLVQRRCSLVSKIAMALGLLGVYSYRAAIGNVIFPWQHDSKDISKGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSR", "length": 917, "header": "tr|A0A8V0YM78-1|A0A8V0YM78_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028684, "end_pos": 53940683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029578.1", "url": "https://www.ensembl.org/id/ENSGALT00010029578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017201.1", "url": "https://www.ensembl.org/id/ENSGALP00010017201.1" } ] } }, { "isoform_ac": "A0A8V0YM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM83/entry", "sequence": { "sequence": "MRGSTSGSGLERCWPLANRRAGRAGAVAADWPEAGRGGAEDAGSGPGAGRRVGRMRLRLRSGALAAGCLLAEALGVALFLRGFFPLPVRSLPRGEARAQPPAEPAPPGPGIASNWTKIPPPLFRKVVIVLIDALRDDFVFGSKGKQFMPYTTQVIEKGTSYSFIAEAKPPTVTMPRIKALMTGSIPGFIDVVVNLNSPALMSDNLIWQAKAAGKRIIFYGDDTWVKLFPKHFVEYDGTTSFFVSDFTEVDDNVTRHLDRVLKREDWDLLILHYLGLDHIGHMTGPNSPLVGPKLREMDNVLKKIHISLLSKEGEASLPSLLVVCGDHGMSETGSHGGSSEDEVHTPLLFISSAFEKRSGPLTQLELVQQTDLASTLAVGLGLPISRNNVGNIILPVVGSKTMREQLRFLHMNGFQLSTLLQENTPAYEKDLGYEQFKIAEKSHGNWIKLYLEGNNSEILLNLGKKVLKQYLEALRTLSSSLSKQVAQYDMYSMMVGTVIVMEVLLLLFLSVPKALSSRAEFEVPLSPPLFSLLFYLMCLMLCAVHVIVCTSAESLCYFCSMSWLTAVGVMMLISALMCGILSAVGKILENSRLPLKNPGASSSSWSEVDVLILAGTIGHVLSLGASSFIEEEHQTWYFLINTLCLALCQELCRNHFLLKECDLQLGTTMKQNFDSIGEASECKNIDVQAASNSKLGKAASSAEFVKGSDKWISLASPWIILICCRLLRSLNQTGVQWAHRPDFGHWLTRGITEARFVYVFVLGIVFTGTKDLLKSQVISADSSVKSTGLWEVYSGLVLLSALLFRPHNLPVLVFCLLIQTMMTKYIWRPLKFDAAQITIMHYWFGQAFFYFQGNSNGIATVDVSAGFVGLESYVEIPAIFLTAFATYAGPLLWAIHLLCYLSSEVSRNSAAVGHGCFCYALMRSIPVAIYIVLVTGLRYHLFIWSVFSPKLLYEGMHVFITAAICLFFTAMDQNHSQKVQG", "length": 981, "header": "tr|A0A8V0YM83-1|A0A8V0YM83_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group) OS=Gallus gallus OX=9031 GN=PIGG PE=1 SV=1 CANONICAL=A0A8V0YM70-1" }, "locus": { "chromosome": "Z", "start_pos": 54028846, "end_pos": 53918510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029584.1", "url": "https://www.ensembl.org/id/ENSGALT00010029584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017206.1", "url": "https://www.ensembl.org/id/ENSGALP00010017206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427290", "resource": "KEGG Pathway" }, { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z3Y1-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class G", "gene_name": "Pigg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLGSGAFAASCVAIEVIGVAIFIRGFFPAPVRSSARPEHDAETPAPEPVAGVRSNWTKLPPPLFSKVVIVLIDALRDDFVFGSKGVKYMPYTTYLVEKGASHSFVAEAKPPTVTMPRIKALMTGSLPGFVDVIRNLNSPVLLEDNVLRQAKAAGKRIIFYGDETWVKLFPKHFVEYDGTTSFFVSDYIEVDKNVTRHLDKVLKRGDWDVLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLLSKDRETLLPSLLVLCGDHGMSETGSHGASSTEEVSTPLLLISSAFERKPGDIRHPKHVQQTDLAATLAIGLGLPIPKDSVGSLLFPVIEGKPMREQLRFLHLNTLQLSKLLQENVPSYEKDPGFEQFKMAEKLHGNWVKLHLEENHSDILLGLGTKVLRHYLGALKTLSLSLSTQVAQYDMYSMAVGTLIVLEVLALFLLSTPHVLCRKAELDVPLLSPVFSLLFYLVFLVLSAIHVLVCTSSESSCYLCSLSWLAVGAVMLLVSALFCAILSALIRMVIDSTLLKKNAADASSGWSEVNLLLLLGTVGHVLSLGASSFVEEEHQTWYFLINTLCLALSQETCRSYFLGDECEPQRHSHVEQQCVNLLACPLQDSTSYNTPESGTAGKRVSLLEAQGSCKWWTVLASPWLVLLCCRLLRSLNQTGVQGAHRPDFSHWLTSSDHKVQLSGLAALSLVVIFMLVQRRCSLVSKVALALGLLGVFCYRAAIGIVQFPWQSDNKGISKGIIEARFVYVFVLGILFTGTKDLLKAQVIATDFKTKTVGLWEMHSGLVLLAALLLRPHNLPVLAFSLLIQTVMTKFIWKPLRHDAAEITVMHYWFGQAFFYFQGNSNNIATIDISAGFVGLDTYMEVPATFLTVFGTYVGPVLWASHLVYFLSSEGNNSALSRSCFCYALICSVPVATYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAICAVFTATNQTRHRRA", "length": 983 }, "evidence": [ { "id": "A0A8V0YM70", "url": "https://omabrowser.org/oma/group/A0A8V0YM70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F4IJJ8-1", "protein_name": "Alkaline-phosphatase-like family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTTAAMTCTRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQELSGISSKYDRLILMVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLRNHSNSTISTHRETSLGQILKLKLGFPCLVPLCINSILLTAYTVVLLLMRNHLFVWSVFSPKYLYVCATTLCTYIGVCIVAATVTYTFYVTTFLRSNRTRHNNS", "length": 958 }, "evidence": [ { "id": "A0A8V0YM70", "url": "https://omabrowser.org/oma/group/A0A8V0YM70/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "M0R9J2-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class G", "gene_name": "Pigg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLGSGAFAASCVAIEVIGVAIFIRGFFPAPVRSSARPEHGAETPAPEPVAGVSSNWTKLPPPLFSKVVIMLIDALRDDFVFGSKGVKYMPYTTYLVEKGASHSFVAEAKPPTVTMPRIKALMTGSLPGFVDVIRNLNSPVLLEDNVIRQAKAAGKRIIFYGDETWVKLFPKHFVEYDGTTSFFVSDYIEVDNNVTRHLDKVLRRGDWDVLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLLSKDRETLLPSLLVLCGDHGMSETGSHGASSTEEVSTPLLLISSAFERKPGDVRHPKHVQQTDLAATLAIGLGLPIPKDNVGSLLFPVIEGKQMREQLRFLHLNTLQLSKLLQENIPAYEKDPGFEQFKMAERLHGNWVKLHLEENHSDILLGLGTKVLRQYLGALKTLSQSLSTQVAHYDIYSMAVGTLMVLEVLTLFLLSTPHVLCRKAELDVPLLSPVFSLLFYLIFLVLSAIHVLVCTSSESSCYLCNLPWLAAGAVMVLVSALFCAILSALIRMVTDGTLLRKNATVASSGWSEVNLLLLLGTVGHVLSLGASSFVEEEHQTWYFLINTLCLALSQETCRSYFLGDDCEPQHHFQVEQKCVNVLACTLQDSTSCSTPESESDTAGKRASLLEAHRSCKWWTVLASPWLVLICCRLLRSLNQTGVQGAHRPDFSHWLTSSDHKVHLSGLAALSLVVIFILVQKGCSLVSKVALALGLLGVFCYRAAIGIVLFPWQPDNKGISKGITEARFVYVFVLGILFTGTKDLLKAQVIAADFKTKIVGLWEIHSGLVLLAALLLRPHNLPVLAFSLLIQTVMTKFIWKPLRHDAAEVTVMHYWFGQAFFYFQGNSNNIATIDISAGCVGLETYMEVPATFLTVFGTYVGPVLWASHLVYFLSSEGNNGSALSRACFCYALICSVPVATYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAICAVFTATNQTRHSRA", "length": 986 }, "evidence": [ { "id": "A0A8V0YM70", "url": "https://omabrowser.org/oma/group/A0A8V0YM70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5H8A4-1", "protein_name": "GPI ethanolamine phosphate transferase 2, catalytic subunit", "gene_name": "PIGG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLGSGTFATCCVAIEVLGIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILISSAFERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMREQLRFLHLNTVQLSKLLQENVPSYEKDPGFEQFKMSERLHGNWIRLYLEEKHSEVLFNLGSKVLRQYLDALKTLSLSLSAQVAQYDIYSMMVGTVVVLEVLTLLLLSVPQALRRKAELEVPLSSPGFSLLFYLVILVLSAVHVIVCTSAESSCYFCGLSWLAAGGVMVLASALLCVIVSVLTNVLVGGNTPRKNPMHPSSRWSELDLLILLGTAGHVLSLGASSFVEEEHQTWYFLVNTLCLALSQETYRNYFLGDDGEPPCGLCVEQGHDGATAAWQDGPGCDVLERDKGHGSPSTSEVLRGREKWMVLASPWLILACCRLLRSLNQTGVQWAHRPDLGHWLTSSDHKAELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWRPDSKDISKGIIEARFVYVFVLGILFTGTKDLLKSQVIAADFKLKTVGLWEIYSGLVLLAALLFRPHNLPVLAFSLLIQTLMTKFIWKPLRHDAAEITVMHYWFGQAFFYFQGNSNNIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASHLVHFLSSETRSGSALSHACFCYALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAVCVFFTAMDQTRLTQS", "length": 983 }, "evidence": [ { "id": "A0A8V0YM70", "url": "https://omabrowser.org/oma/group/A0A8V0YM70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "pmid": "" }, { "name": "CP2 mannose-ethanolamine phosphotransferase activity", "id": "GO:0051267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM70" }, { "id": "PF19316", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GPI ethanolamine phosphate transferase 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 708, "end_pos": 1018, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1038, "end_pos": 1040 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 731, "end_pos": 733 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLT3-1", "uniprot_ac": "A0A8V0YLT3", "uniprot_id": "A0A8V0YLT3_CHICK", "mass": { "chemical_mass": 41980.0, "monoisotopic_mass": 41980.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFA10", "type": "recommended", "evidence": [ { "id": "A0A8V0YLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT7#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" }, { "database": "UniProtKB", "id": "PIRNR000543", "url": "https://www.uniprot.org/uniprotkb/PIRNR000543#function" }, { "database": "UniProtKB", "id": "A0A8V0YFF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF3#function" }, { "database": "UniProtKB", "id": "A0A8V0YFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG7#function" }, { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3#function" }, { "database": "UniProtKB", "id": "A0A8V0YLU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFA10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3", "locus": { "chromosome": "7", "start_pos": 6587477, "end_pos": 6627337, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013783", "url": "https://www.ensembl.org/id/ENSGALG00010013783" } ] } } ], "crossref": [ { "id": "A0A8V0YLT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424032", "url": "https://www.ncbi.nlm.nih.gov/gene/424032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424032", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPHNKKM", "url": "https://omabrowser.org/oma/group/DPHNKKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFF3", "url": "https://www.orthodb.org/?gene=A0A8V0YFF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFG7", "url": "https://www.orthodb.org/?gene=A0A8V0YFG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT3", "url": "https://www.orthodb.org/?gene=A0A8V0YLT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT7", "url": "https://www.orthodb.org/?gene=A0A8V0YLT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLU3", "url": "https://www.orthodb.org/?gene=A0A8V0YLU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGQGVVLERSPYSDFVFLDAMFKQGYIHKRCVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMSETSEILHYTASEAEDVEKVIEDIEYLKFDKGPWLEQDDVSFHHLRLFVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSWKAPLSISNPAGADVHLLRLLGLSGGISAPT", "length": 370, "header": "tr|A0A8V0YLT3-1|A0A8V0YLT3_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF3/entry", "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGQGVVLERSPYSDFVFLDAMFKQGYIHKRCVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMSETSEILHYTASEAEDVEKVIEDIEYLKFDKGPWLEQDDVSFHHLRLFVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSPSGTGNVHSAKDVKHSCFS", "length": 358, "header": "tr|A0A8V0YFF3-1|A0A8V0YLT3_CHICK Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "locus": { "chromosome": "7", "start_pos": 6627302, "end_pos": 6599284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033092.1", "url": "https://www.ensembl.org/id/ENSGALT00010033092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019566.1", "url": "https://www.ensembl.org/id/ENSGALP00010019566.1" } ] } }, { "isoform_ac": "A0A8V0YFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG7/entry", "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMSETSEILHYTASEAEDVEKVIEDIEYLKFDKGPWLEQDDVSFHHLRLFVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSLPGRNYKKGYNAEVGDKWIWLK", "length": 332, "header": "tr|A0A8V0YFG7-1|A0A8V0YLT3_CHICK Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "locus": { "chromosome": "7", "start_pos": 6627302, "end_pos": 6588652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033120.1", "url": "https://www.ensembl.org/id/ENSGALT00010033120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019581.1", "url": "https://www.ensembl.org/id/ENSGALP00010019581.1" } ] } }, { "isoform_ac": "A0A8V0YLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3/entry", "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGQGVVLERSPYSDFVFLDAMFKQGYIHKRCVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMSETSEILHYTASEAEDVEKVIEDIEYLKFDKGPWLEQDDVSFHHLRLFVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSWKAPLSISNPAGADVHLLRLLGLSGGISAPT", "length": 370, "header": "tr|A0A8V0YLT3-1|A0A8V0YLT3_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "locus": { "chromosome": "7", "start_pos": 6627302, "end_pos": 6593686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033096.1", "url": "https://www.ensembl.org/id/ENSGALT00010033096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019568.1", "url": "https://www.ensembl.org/id/ENSGALP00010019568.1" } ] } }, { "isoform_ac": "A0A8V0YLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT7/entry", "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGQGVVLERSPYSDFVFLDAMFKQGYIHKRCVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMRPVKFCTTQQVRQRMWRSVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSLPGRNYKKGYNAEVGDKWIWLK", "length": 331, "header": "tr|A0A8V0YLT7-1|A0A8V0YLT7_CHICK Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "locus": { "chromosome": "7", "start_pos": 6627302, "end_pos": 6588652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033110.1", "url": "https://www.ensembl.org/id/ENSGALT00010033110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019573.1", "url": "https://www.ensembl.org/id/ENSGALP00010019573.1" } ] } }, { "isoform_ac": "A0A8V0YLU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU3/entry", "sequence": { "sequence": "MSLWRARLGPAAAATVTSAARGRLRSAVLPAASVHISSQRPLQYGWLAYMLGERASKKFSEYSKIFTVDGNLSSGKGKLAQHIADKLGMKYFPEADIHYQDRIAGDGTLLDERFNGFCNLERFYNDPKCPDGHSYRLQAWLFGNRILQYSDALEHLLTTGQGVVLERSPYSDFVFLDAMFKQGYIHKRCVDHYKEIKEISICEFLPPHLVIYLDVPVPDVQKRLQEKGEPYEKKVSASYLQNIEDAYKKTFIPEMSETSEILHYTASEAEDVEKVIEDIEYLKFDKGPWLEQDDVSFHHLRLFVQDKDGVLDPVAIPRFIPEITIGGTEYDKIYYEFRSLPGRNYKKGYNAEVGDKWIWLK", "length": 361, "header": "tr|A0A8V0YLU3-1|A0A8V0YLU3_CHICK Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFA10 PE=1 SV=1 CANONICAL=A0A8V0YLT3-1" }, "locus": { "chromosome": "7", "start_pos": 6627302, "end_pos": 6588652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033115.1", "url": "https://www.ensembl.org/id/ENSGALT00010033115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019578.1", "url": "https://www.ensembl.org/id/ENSGALP00010019578.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424032", "resource": "KEGG Pathway" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FAQ6-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALRLLRLVPATASARGPAAGVQRVGQIHTSVQNQMKYGALAFMLGEKTTKKLTEYSRVITVDGNICSGKSKLAKDIAEKLGMRHFPEADVQYSSSTTGDGRPLSTEFNGSCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFVEAMYNQGYIRKECVDHYNEVKQLTLPEYLPPHAVIYIDVPVPEIKSRIQKKGDPHEMKVTSAYLQDIENAYKNTFLPQMSEQCEVLVYNTWESEDSTKVVEDIEYLNYNKGPWLKQDDRTFHHLRMLVQDKMDVLNYTTIPIYLPEITVGPHQGTRIYNSFKQCPPTKLYSAARMAEKTVEAADSNHTFLCLHIFLTSLCSSIGVKSHFQPFSQGSEA", "length": 388 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SAR7-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "NDUFA10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "GAVVTTGPGAASAPHTAPPQNPRRAGLPLGSRRREDRPSESRRRSSLPWEPGRREDNPSELTPQNSGCGQALRRRVEADAKGDPWRTSPRLRAVRLHSPPEHSRQARRGHPSRDVTAARRQRERTLSRPRPLGSLSRCRQRSHGLEAAETCPTARGLKHFPEAGIHYVDSTTGDGKPLPVQFSGNCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTICEYLPPHVVVYVDVPVPEVQSRIQKKGNPHEMKITSAYLQDIENAYKGTFLPEMSEKCEVLQYSAWEAQDAEKVVEDIEYLKYDKGPWLDQNDRKLHKLRMLVQDKLEVLNYTSIPVFLPEVTVGAHQSDQVFQEFTELPGRKYRAGYNEDVGDKWIWLK", "length": 429 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SIS9-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "NDUFA10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRLLRLAPASASAVPRGLGAVAQRVGGIHTGAPCRLQYGPLAFVLGERTTRKLTETSKVITVDGNICSGKGRLAREIAEKLGLRHFPEAGIHYADSTTGDGKPLDVQLSGNCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVEHYNEVKKVTACEYLPPHVVVYVDVPVPEIQSRIQKKGNPHEMKITAAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAEDAEKVVEDIEYLKCDKGPWPDQDDRTFHRLRMLVQNKLEVLNYTTIPVYLPEITIGAHQSDRVFQKFTELPGRKYSPGYNEDVGDKWIWLK", "length": 357 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95299-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "NDUFA10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDDPRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIRKQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P91929-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "ND-42", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTAVFRVGLVRLVSRATQSPNLLQAQTNALPAAFQQRCSISGKTMRGGPRVPKAAPYPYKTKKYSVFNAIFDKTSKRFDENSKVICVEGPIAAGKSKFAKELAEELDMEYYPAVDLDLIYINSYGYDMRKLDPQLPPSCRSYDVRNFCLDPSHDLAAQFQIRMYMLRYSQYIDALQHVLSTGQGVVLERSPYSDFVFMEAMFRQGYLSRGARSVYNELRQNTIGELLKPHLVIYLDLPVDAVKKQIKARNVDYEVQSKVFSDAYLSDLEQLYKQQYLKDISTHAELLIYDWTAGGETEVVVEDIERIDFNQFEADIHNKKMLDWRFPLEAEWCEARIKYCHEKPDLMNYFNVPRFDVPELVRSADDGKVWRDVWFNAPGMKYRPGYNADMGDEGLLTKTKIGINQGI", "length": 407 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99LC3-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRLLRLVPASAPARGLAAGAQRVGRIHTSVHCKLRYGLLAAILGDKTTKKLHEYSRVITVDGNICSGKNKLAKEIAQQLGMKHYPEAGIQYSSTTTGDGRPLDIEFSGSCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGYIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVPEVQSRIQKKGDPHEMKVTSAYLQDIENAYKKTFLPKMSEMCEVLVYDSWEAEDPTKVVEDIEYLKYNKGPWLKQDDWTFHYLRMLVQDKTEVLNYTTIPVYLPEITIGAHQGSRIYNSFRELPGRKYAPGYNAEVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0YLT3", "url": "https://omabrowser.org/oma/group/A0A8V0YLT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT3" }, { "id": "PF01712", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01712" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deoxynucleoside kinase", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 278, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YM08-1", "uniprot_ac": "A0A8V0YM08", "uniprot_id": "A0A8V0YM08_CHICK", "mass": { "chemical_mass": 73589.0, "monoisotopic_mass": 73589.0 }, "refseq": { "ac": "XP_015144876", "name": "glutaminase kidney isoform, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876" }, "gene_names": [ { "name": "GLS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ] }, { "name": "GLS2", "type": "synonym", "evidence": [ { "id": "XP_015144876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876" } ] }, { "name": "GLS", "type": "synonym", "evidence": [ { "id": "XP_015144876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876" } ] } ], "protein_names": [ { "name": "glutaminase", "type": "recommended", "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08/entry#names_and_taxonomy" } ] }, { "name": "glutaminase kidney isoform, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015144876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08", "locus": { "chromosome": "7", "start_pos": 7510759, "end_pos": 7458284, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013872", "url": "https://www.ensembl.org/id/ENSGALG00010013872" } ] } } ], "crossref": [ { "id": "A0A8V0YM08", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM08", "database": "AlphaFoldDB", "categories": [] }, { "id": "424043", "url": "https://www.ncbi.nlm.nih.gov/gene/424043", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FACPLSG", "url": "https://omabrowser.org/oma/group/FACPLSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFM3", "url": "https://www.orthodb.org/?gene=A0A8V0YFM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFM7", "url": "https://www.orthodb.org/?gene=A0A8V0YFM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM08", "url": "https://www.orthodb.org/?gene=A0A8V0YM08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12544:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12544:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8964539", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015144876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15889", "url": "https://www.rhea-db.org/rhea/15889", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMRLWRAALLRELLLLGPPGAAGGGGPGSGSRRLPPQLAALGAGPATRRGPGPARGLCTRSEGALEEPGKGAQQPAAPSEPPDGGRNNNHGSGDKELAGGGGGGEKEESCVWSNPESKSNREFSSPRAPSGRKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGANNAEKFDYVMQFMNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVAILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGLMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSGMDMEQRDYDSRTALHVAAAEGHVDVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPSEDSSNGKENRTVHKNLDGLL", "length": 672, "header": "tr|A0A8V0YM08-1|A0A8V0YM08_CHICK Isoform 1 of glutaminase OS=Gallus gallus OX=9031 GN=GLS2 PE=1 SV=1 CANONICAL=A0A8V0YM08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM3/entry", "sequence": { "sequence": "MDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGANNAEKFDYVMQFMNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVAILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGLMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRHSFGPMDYENLQQELALKETVWKKVSPESNEDISRTVVYRMEGRGEQN", "length": 420, "header": "tr|A0A8V0YFM3-1|A0A8V0YM08_CHICK Computationally mapped isoform of glutaminase OS=Gallus gallus OX=9031 GN=GLS2 PE=1 SV=1 CANONICAL=A0A8V0YM08-1" }, "locus": { "chromosome": "7", "start_pos": 7495186, "end_pos": 7465249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033269.1", "url": "https://www.ensembl.org/id/ENSGALT00010033269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019643.1", "url": "https://www.ensembl.org/id/ENSGALP00010019643.1" } ] } }, { "isoform_ac": "A0A8V0YFM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM7/entry", "sequence": { "sequence": "MMRLWRAALLRELLLLGPPGAAGGGGPGSGSRRLPPQLAALGAGPATRRGPGPARGLCTRSEGALEEPGKGAQQPAAPSEPPDGGRNNNHGSGDKELAGGGGGGENKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGANNAEKFDYVMQFMNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVAILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGLMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSGMDMEQRDYDSRTALHVAAAEGHVDVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPSEDSSNGKENRTVHKNLDGLL", "length": 646, "header": "tr|A0A8V0YFM7-1|A0A8V0YM08_CHICK Computationally mapped isoform of glutaminase OS=Gallus gallus OX=9031 GN=GLS2 PE=1 SV=1 CANONICAL=A0A8V0YM08-1" }, "locus": { "chromosome": "7", "start_pos": 7510572, "end_pos": 7458332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033282.1", "url": "https://www.ensembl.org/id/ENSGALT00010033282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019648.1", "url": "https://www.ensembl.org/id/ENSGALP00010019648.1" } ] } }, { "isoform_ac": "A0A8V0YM08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08/entry", "sequence": { "sequence": "MMRLWRAALLRELLLLGPPGAAGGGGPGSGSRRLPPQLAALGAGPATRRGPGPARGLCTRSEGALEEPGKGAQQPAAPSEPPDGGRNNNHGSGDKELAGGGGGGEKEESCVWSNPESKSNREFSSPRAPSGRKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGANNAEKFDYVMQFMNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVAILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGLMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSGMDMEQRDYDSRTALHVAAAEGHVDVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPSEDSSNGKENRTVHKNLDGLL", "length": 672, "header": "tr|A0A8V0YM08-1|A0A8V0YM08_CHICK Isoform 1 of glutaminase OS=Gallus gallus OX=9031 GN=GLS2 PE=1 SV=1 CANONICAL=A0A8V0YM08-1" }, "locus": { "chromosome": "7", "start_pos": 7510572, "end_pos": 7458332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033277.1", "url": "https://www.ensembl.org/id/ENSGALT00010033277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019645.1", "url": "https://www.ensembl.org/id/ENSGALP00010019645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BFF4-1", "protein_name": "glutaminase", "gene_name": "GLS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMRLRGSAMLRNLLLRPPAATCAVLRRAQPLATLCRRSRGGGRTGPAAAARLHPWWGGGGRPAGPLARGLSSSPSEILQELGKGGTQQQQQPGASPPAAPPAPSPKDSPGETDGFGNSEGKELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL", "length": 669 }, "evidence": [ { "id": "A0A8V0YM08", "url": "https://omabrowser.org/oma/group/A0A8V0YM08/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z7P3-1", "protein_name": "Glutaminase kidney isoform, mitochondrial", "gene_name": "Gls", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMRLRGSAMLRELLLRPPAAVGAVLRRAQPLGTLCRRPRGGSRPTAGLVAAARLHPWWGGGGRAKGPGAGGLSSSPSEILQELGKGGTPPQQQQQQQQQPGASPPAAPGPKDSPGETDAFGNSEGKEMVAAGDNKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDDGKGNQTVHKNLDGLL", "length": 674 }, "evidence": [ { "id": "A0A8V0YM08", "url": "https://omabrowser.org/oma/group/A0A8V0YM08/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O94925-1", "protein_name": "Glutaminase kidney isoform, mitochondrial", "gene_name": "GLS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGGGGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEGKELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL", "length": 669 }, "evidence": [ { "id": "A0A8V0YM08", "url": "https://omabrowser.org/oma/group/A0A8V0YM08/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13264-1", "protein_name": "Glutaminase kidney isoform, mitochondrial", "gene_name": "Gls", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMRLRGSAMLRELLLRPPAAVGGVLRRTQPLGTLCRRPRGGSRPAAGLVAAARLHPWWGGGGRAKGPGSGGLSSSPSEILQELGKGGTPPQQQQQQQQQPGASPPAAPGPKDSPGETDAFGNSEGKEMVAAGDNKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDDGKENQTVHKNLDGLL", "length": 674 }, "evidence": [ { "id": "A0A8V0YM08", "url": "https://omabrowser.org/oma/group/A0A8V0YM08/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LWI2-1", "protein_name": "glutaminase", "gene_name": "glsa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLHFRLSRALKEICKPNVRRVWRNNTDETTVAGGRASSSRRALCTQTDAANDKRRKAGILPSLEDLLFYTIAEGQEKIPAHKFTTALKATGLRTGDPRLKECMEMLKITLKTTSDGALDRHLFKKCVQSNIVLLTQAFRKKFVIPDFQSFTSHIDQIYESAKSLSGGQVADYIPQLAKFSPNLWAVSLCTVDGQRYTAGDTKVPFCLQSCVKPLKYAIAVHDHGTEYVHRFIGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVCTSLLKQGVSNAEKFDYVLNFMKKLAGNEYVGFSNATFQSERLSGDRNFAIGYYLKEKKCFPEGTDMISILDLYFQLCSIEVTCESASVMAATLANGGFCPITGERVVNPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVSGGILLVVPNVMGIMCWSPPLDKLGNSVRGIQFCTDLVQLFNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSSMDMEQRDYDSRTALHVAAAEGHAEVVRFLLEACKVNPVPKDRWGNTPMDEAIHFGHHDVVTILQDYHNTYSPKESSADSEKETAEKNLDGML", "length": 591 }, "evidence": [ { "id": "A0A8V0YM08", "url": "https://omabrowser.org/oma/group/A0A8V0YM08/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "glutamine metabolic process", "id": "GO:0006541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006541", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" }, { "name": "glutamate biosynthetic process", "id": "GO:0006537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" }, { "name": "L-glutamine catabolic process", "id": "GO:0006543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" }, { "name": "intracellular glutamate homeostasis", "id": "GO:0090461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090461", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutaminase activity", "id": "GO:0004359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15889", "name": "", "equation": "L-glutamine + H2O = L-glutamate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YM08-1", "A0A8V0Y085-1" ], "evidence": [ { "id": "15889", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15889" } ] }, { "id": "R-GGA-70609", "name": "glutamine + H2O => glutamate + NH4+ (GLS)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113522" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YM08-1" ], "evidence": [ { "id": "R-GGA-70609", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70609" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113522", "participant_name": "L-Gln [mitochondrial matrix]", "crossref": [ { "id": "58359", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532526", "database": "ZINC", "url": "" }, { "id": "C00064", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y085", "gene_name": "CAD", "activity": [ { "ec_number": "6.3.4.16", "activity": "hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "2.1.3.2", "activity": "carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "3.5.2.3", "activity": "(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H(+).", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "6.3.5.5", "activity": "hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "3.5.1.2", "activity": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "3.5.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "3.5.1.2", "activity": "", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "6.3.5.5", "activity": "", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "2.1.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] }, { "ec_number": "6.3.4.16", "activity": "", "evidence": [ { "id": "A0A8V0Y085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y085" } ] } ] }, { "uniprot_ac": "A0A8V0YM08", "gene_name": "GLS2", "activity": [ { "ec_number": "3.5.1.2", "activity": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ] }, { "ec_number": "3.5.1.2", "activity": "", "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM08" }, { "id": "PF17959", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17959" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutaminase EF-hand", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 225, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.2", "ec_name": "L-glutamine + H2O = L-glutamate + NH4(+).", "evidence": [ { "id": "3.5.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2" }, { "id": "3.5.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 378, "end_pos": 380 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 661, "end_pos": 663 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YP10-1", "uniprot_ac": "A0A8V0YP10", "uniprot_id": "A0A8V0YP10_CHICK", "mass": { "chemical_mass": 89808.0, "monoisotopic_mass": 89808.0 }, "refseq": {}, "gene_names": [ { "name": "STAT1", "type": "recommended", "evidence": [ { "id": "A0A8V0YP10", "database": "UniProtKB", "url": 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} ], "crossref": [ { "id": "A0A8V0YP10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16845", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16845", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", 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"https://www.ebi.ac.uk/interpro/entry/IPR035859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFT7", "url": "https://www.orthodb.org/?gene=A0A8V0YFT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT5", "url": "https://www.orthodb.org/?gene=A0A8V0YLT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { 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"Protein" ] }, { "id": "A0A8V0YLT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASVRVFLGAGKKRERSGGAVCSSGMTQWYQLQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLENQDWEHAANNVSFATVLFHDLLSQLDDQFSRFLIENNFLLQHNIRKSKRNLQDNFQEDPIHMAMIIHNCLKEERKILNSAQLSNQMEVGGVQNTMTGMLDKQKELDAKVKAVKNSVTDVEQDIKTLEDVQDEYDFKHKTFQNREYEPNGASQEECKKEQMNLQKMFFLLDIKRKEVVAKIIQLLNTTEHTQSALINEELVEWKRRQQTACIGGPPNACLDQLQNWFTIIAESLQQVRQQLKKLEELEQKLTYDPDPITKNKQVLQDRTHSLFKQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNEKNSVKGFRKFNILGTNTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIELETTSLPIIVISNVSQLPSGWASILWFNMLSTDPKNLSFFLNPPCAKWSKLSEVLSWQFSSVTKRGLNADQLNMLGEKLLGPTSGGSHDGLIPWTRFCKENINDKNFPFWLWIEGILELIKKHLLCLWNDGCIMGFISKDKERALLKDQRPGTFLLRFSESSKEGAITFTWVEGSQNEPQFHSVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLRFLYPDIPKDNAFGKYYSRPKEAPEPMDTDTPKGNGYIRTELISVSEVHPSRLQSPENLLPMSPEEFDEVSRMVDPAEIDTVMCSAYTA", "length": 781, "header": "tr|A0A8V0YP10-1|A0A8V0YP10_CHICK Isoform 1 of Signal transducer and activator of transcription OS=Gallus gallus OX=9031 GN=STAT1 PE=1 SV=1 CANONICAL=A0A8V0YP10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT7/entry", "sequence": { "sequence": "MAASVRVFLGAGKKRERSGGAVCSSGMTQWYQLQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLENQDWEHAANNVSFATVLFHDLLSQLDDQFSRFLIENNFLLQHNIRKSKRNLQDNFQEDPIHMAMIIHNCLKEERKILNSAQLSNQMEVGGVQNTMTGMLDKQKELDAKVKAVKNSVTDVEQDIKTLEDVQDEYDFKHKTFQNREYEPNGASQEECKKEQMNLQKMFFLLDIKRKEVVAKIIQLLNTTEHTQSALINEELVEWKRRQQTACIGGPPNACLDQLQNWFTIIAESLQQVRQQLKKLEELEQKLTYDPDPITKNKQVLQDRTHSLFKQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNEKNSVKGFRKFNILGTNTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIELETTSLPIIVISNVSQLPSGWASILWFNMLSTDPKNLSFFLNPPCAKWSKLSEVLSWQFSSVTKRGLNADQLNMLGEKLLGPTSGGSHDGLIPWTRFCKENINDKNFPFWLWIEGILELIKKHLLCLWNDGCIMGFISKDKERALLKDQRPGTFLLRFSESSKEGAITFTWVEGSQNEPQFHSVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLRFLYPDIPKDNAFGKYYSRPKEERRGSSGTEDLGSLTHTGVLLS", "length": 736, "header": "tr|A0A8V0YFT7-1|A0A8V0YP10_CHICK Computationally mapped isoform of Signal transducer and activator of transcription OS=Gallus gallus OX=9031 GN=STAT1 PE=1 SV=1 CANONICAL=A0A8V0YP10-1" }, "locus": { "chromosome": "7", "start_pos": 7534877, "end_pos": 7518213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033410.1", "url": "https://www.ensembl.org/id/ENSGALT00010033410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019710.1", "url": "https://www.ensembl.org/id/ENSGALP00010019710.1" } ] } }, { "isoform_ac": "A0A8V0YLT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT5/entry", "sequence": { "sequence": "MAASVRVFLGAGKKRERSGGAVCSSGEHAANNVSFATVLFHDLLSQLDDQFSRFLIENNFLLQHNIRKSKRNLQDNFQEDPIHMAMIIHNCLKEERKILNSAQLSNQMEVGGVQNTMTGMLDKQKELDAKVKAVKNSVTDVEQDIKTLEDVQDEYDFKHKTFQNREYEPNGASQEECKKEQMNLQKMFFLLDIKRKEVVAKIIQLLNTTEHTQSALINEELVEWKRRQQTACIGGPPNACLDQLQNWFTIIAESLQQVRQQLKKLEELEQKLTYDPDPITKNKQVLQDRTHSLFKQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNEKNSVKGFRKFNILGTNTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIELETTSLPIIVISNVSQLPSGWASILWFNMLSTDPKNLSFFLNPPCAKWSKLSEVLSWQFSSVTKRGLNADQLNMLGEKLLGPTSGGSHDGLIPWTRFCKENINDKNFPFWLWIEGILELIKKHLLCLWNDGCIMGFISKDKERALLKDQRPGTFLLRFSESSKEGAITFTWVEGSQNEPQFHSVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLRFLYPDIPKDNAFGKYYSRPKEAPEPMDTDTPKGNGYIRTELISVSEVHPSRLQSPENLLPMSPEEFDEVSRMVDPAEIDTVMCSAYTA", "length": 738, "header": "tr|A0A8V0YLT5-1|A0A8V0YLT5_CHICK Computationally mapped isoform of Signal transducer and activator of transcription OS=Gallus gallus OX=9031 GN=STAT1 PE=1 SV=1 CANONICAL=A0A8V0YP10-1" }, "locus": { "chromosome": "7", "start_pos": 7534877, "end_pos": 7516359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033418.1", "url": "https://www.ensembl.org/id/ENSGALT00010033418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019714.1", "url": "https://www.ensembl.org/id/ENSGALP00010019714.1" } ] } }, { "isoform_ac": "A0A8V0YP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP10/entry", "sequence": { "sequence": "MAASVRVFLGAGKKRERSGGAVCSSGMTQWYQLQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLENQDWEHAANNVSFATVLFHDLLSQLDDQFSRFLIENNFLLQHNIRKSKRNLQDNFQEDPIHMAMIIHNCLKEERKILNSAQLSNQMEVGGVQNTMTGMLDKQKELDAKVKAVKNSVTDVEQDIKTLEDVQDEYDFKHKTFQNREYEPNGASQEECKKEQMNLQKMFFLLDIKRKEVVAKIIQLLNTTEHTQSALINEELVEWKRRQQTACIGGPPNACLDQLQNWFTIIAESLQQVRQQLKKLEELEQKLTYDPDPITKNKQVLQDRTHSLFKQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNEKNSVKGFRKFNILGTNTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIELETTSLPIIVISNVSQLPSGWASILWFNMLSTDPKNLSFFLNPPCAKWSKLSEVLSWQFSSVTKRGLNADQLNMLGEKLLGPTSGGSHDGLIPWTRFCKENINDKNFPFWLWIEGILELIKKHLLCLWNDGCIMGFISKDKERALLKDQRPGTFLLRFSESSKEGAITFTWVEGSQNEPQFHSVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLRFLYPDIPKDNAFGKYYSRPKEAPEPMDTDTPKGNGYIRTELISVSEVHPSRLQSPENLLPMSPEEFDEVSRMVDPAEIDTVMCSAYTA", "length": 781, "header": "tr|A0A8V0YP10-1|A0A8V0YP10_CHICK Isoform 1 of Signal transducer and activator of transcription OS=Gallus gallus OX=9031 GN=STAT1 PE=1 SV=1 CANONICAL=A0A8V0YP10-1" }, "locus": { "chromosome": "7", "start_pos": 7534877, "end_pos": 7516359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033422.1", "url": "https://www.ensembl.org/id/ENSGALT00010033422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019718.1", "url": "https://www.ensembl.org/id/ENSGALP00010019718.1" } ] } }, { "isoform_ac": "A0A8V0YP14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP14/entry", "sequence": { "sequence": "MAASVRVFLGAGKKRERSGGAVCSSGMTQWYQLQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLENQDWEHAANNVSFATVLFHDLLSQLDDQFSRFLIENNFLLQHNIRKSKRNLQDNFQEDPIHMAMIIHNCLKEERKILNSAQLSNQMEVGGVQNTMTGMLDKQKELDAKVKAVKNSVTDVEQDIKTLEDVQDEYDFKHKTFQNREYEPNGASQEECKKEQMNLQKMFFLLDIKRKEVVAKIIQLLNTTEHTQSALINEELVEWKRRQQTACIGGPPNACLDQLQNWFTIIAESLQQVRQQLKKLEELEQKLTYDPDPITKNKQVLQDRTHSLFKQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNEKNSVKGFRKFNILGTNTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIELETTSLPIIVISNVSQLPSGWASILWFNMLSTDPKNLSFFLNPPCAKWSKLSEVLSWQFSSVTKRGLNADQLNMLGEKLLGPTSGGSHDGLIPWTRFCKENINDKNFPFWLWIEGILELIKKHLLCLWNDGCIMGFISKDKERALLKDQRPGTFLLRFSESSKEGAITFTWVEGSQNEPQFHSVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLRFLYPDIPKDNAFGKYYSRPKEATHPGSNLQKICCLCLLKSLMRYLGWWIQQRLTQ", "length": 748, "header": "tr|A0A8V0YP14-1|A0A8V0YP14_CHICK Computationally mapped isoform of Signal transducer and activator of transcription OS=Gallus gallus OX=9031 GN=STAT1 PE=1 SV=1 CANONICAL=A0A8V0YP10-1" }, "locus": { "chromosome": "7", "start_pos": 7534877, "end_pos": 7516965, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033431.1", "url": "https://www.ensembl.org/id/ENSGALT00010033431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019723.1", "url": "https://www.ensembl.org/id/ENSGALP00010019723.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ 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"https://www.reactome.org/PathwayBrowser/#R-GGA-877312", "resource": "Reactome", "description": "Regulation of IFNG signaling" }, { "id": "R-GGA-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" }, { "id": "R-GGA-8984722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8984722", "resource": "Reactome", "description": "Interleukin-35 Signalling" }, { "id": "R-GGA-8985947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8985947", "resource": "Reactome", "description": "Interleukin-9 signaling" }, { "id": "R-GGA-9020956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020956", "resource": "Reactome", "description": "Interleukin-27 signaling" }, { "id": "R-GGA-9020958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020958", "resource": "Reactome", "description": "Interleukin-21 signaling" }, { "id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ] } ], "protein_names": [ { "name": "Flavin-containing monooxygenase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8/entry#names_and_taxonomy" } ] }, { "name": "1.-.-.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG00#function" }, { "database": "UniProtKB", "id": "ARBA00045957", "url": "https://www.uniprot.org/uniprotkb/ARBA00045957#function" }, { "database": "UniProtKB", "id": "A0A8V0YM02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM02#function" }, { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FMO4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8", "locus": { "chromosome": "8", "start_pos": 4794822, "end_pos": 4805448, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013980", "url": "https://www.ensembl.org/id/ENSGALG00010013980" } ] } } ], "crossref": [ { "id": "A0A8V0YMD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "770587", "url": "https://www.ncbi.nlm.nih.gov/gene/770587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424393", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STHQWAV", "url": "https://omabrowser.org/oma/group/STHQWAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG00", "url": "https://www.orthodb.org/?gene=A0A8V0YG00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM02", "url": "https://www.orthodb.org/?gene=A0A8V0YM02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD8", "url": "https://www.orthodb.org/?gene=A0A8V0YMD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "24468", "url": "https://www.rhea-db.org/rhea/24468", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "31979", "url": "https://www.rhea-db.org/rhea/31979", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69819", "url": "https://www.rhea-db.org/rhea/69819", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "74111", "url": "https://www.rhea-db.org/rhea/74111", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGRLHSLGQDLAANQDDTMVRRVAVIGAGSSGLVATKCCLDEGLEPTCFERSEDIGGLWRFTDKADRGRVSVYRSVISNTSKEMSCFSDFPFPEDFPSFLPHNLFLEYFRMYAQHFQLLRHIRFKTTVISVRKRPDFATSGQWDVVTEAEGTQESHVFDAVMVCAGNFQQPHLPLASFPGIETRFRGQYFHSLEYKDAAAFQGKRVLVVGIGNTGCDIAVDMSRVAAKVFLSARSSTWVFSRVANHGFPWDMLNTTRFNHFLEWLLPSAVMKRIRIWKTNSWFNHEIYGLASAKSSNFNFIINEELPFCMLSGTIVLKSNVKEFTETSAVFEDGTTEENIDVVIFATGYNFSFSFLEESICNPLKNNSTLYKCIFPPQLERPTLAVIGLIKLTGSVMVGSEIQARWVTGVFAGAYKLPPSSKMMAEVSKKQLPVKRNLPEKQNSRLNFISYTSEIASCAGVKPSVLRLLLTNPRLALAVFFGPCTSYQYRLMGRGQWSGAGAAILTQWQRVLKPLRTRVLEDSASSYSWRWLGLLALPMALVVGFLLSKCPKLGWAPRAGLLF", "length": 564, "header": "tr|A0A8V0YMD8-1|A0A8V0YMD8_CHICK Isoform 1 of Flavin-containing monooxygenase OS=Gallus gallus OX=9031 GN=FMO4 PE=3 SV=1 CANONICAL=A0A8V0YMD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG00/entry", "sequence": { "sequence": "MVRRVAVIGAGSSGLVATKCCLDEGLEPTCFERSEDIGGLWRFTDKADRGRVSVYRSVISNTSKEMSCFSDFPFPEDFPSFLPHNLFLEYFRMYAQHFQLLRHIRFKTTVISVRKRPDFATSGQWDVVTEAEGTQESHVFDAVMVCAGNFQQPHLPLASFPGIETRFRGQYFHSLEYKDAAAFQGKRVLVVGIGNTGCDIAVDMSRVAAKVFLSARSSTWVFSRVANHGFPWDMLNTTRFNHFLEWLLPSAVMKRIRIWKTNSWFNHEIYGLASAKSSNFNFIINEELPFCMLSGTIVLKSNVKEFTETSAVFEDGTTEENIDVVIFATGYNFSFSFLEESICNPLKNNSTLYKCIFPPQLERPTLAVIGLIKLTGSVMVGSEIQARWVTGVFAGAYKLPPSSKMMAEVSKKQLPVKRNLPEKQNSRLNFISYTSEIASCAGVKPSVLRLLLTNPRLALAVFFGPCTSYQYRLMGRGQWSGAGAAILTQWQRVLKPLRTRVLEDSASSYSWRWLGLLALPMALVVGFLLSKCPKLGWAPRAGLLF", "length": 545, "header": "tr|A0A8V0YG00-1|A0A8V0YMD8_CHICK Computationally mapped isoform of Flavin-containing monooxygenase OS=Gallus gallus OX=9031 GN=FMO4 PE=3 SV=1 CANONICAL=A0A8V0YMD8-1" }, "locus": { "chromosome": "8", "start_pos": 4804183, "end_pos": 4799890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033520.1", "url": "https://www.ensembl.org/id/ENSGALT00010033520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019766.1", "url": "https://www.ensembl.org/id/ENSGALP00010019766.1" } ] } }, { "isoform_ac": "A0A8V0YM02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM02/entry", "sequence": { "sequence": "MVRRVAVIGAGSSGLVATKCCLDEGLEPTCFERSEDIGGLWRFTDKADRGRVSVYRSVISNTSKEMSCFSDFPFPEDFPSFLPHNLFLEYFRMYAQHFQLLRHIRFKTTVISVRKRPDFATSGQWDVVTEAEGTQESHVFDAVMVCAGNFQQPHLPLASFPGIETRFRGQYFHSLEYKDAAAFQGKRVLVVGIGNTGCDIAVDMSRVAAKVFLSARSSTWVFSRVANHGFPWDMLNTTRFNHFLEWLLPSAVMKRIRIWKTNSWFNHEIYGLASAKSSNFNFIINEELPFCMLSGTIVLKSNVKEFTETSAVFEDGTTEENIDVVIFATGYNFSFSFLEESICNPLKNNSTLYKCIFPPQLERPTLAVIGLIKLTGSVMVGSEIQARWVTGVFAGAYKLPPSSKMMAEVSKKQLPVKSLGATAGVPSSSQKNNFCFRSQ", "length": 439, "header": "tr|A0A8V0YM02-1|A0A8V0YM02_CHICK Computationally mapped isoform of Flavin-containing monooxygenase OS=Gallus gallus OX=9031 GN=FMO4 PE=3 SV=1 CANONICAL=A0A8V0YMD8-1" }, "locus": { "chromosome": "8", "start_pos": 4804183, "end_pos": 4795139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033529.1", "url": "https://www.ensembl.org/id/ENSGALT00010033529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019770.1", "url": "https://www.ensembl.org/id/ENSGALP00010019770.1" } ] } }, { "isoform_ac": "A0A8V0YMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8/entry", "sequence": { "sequence": "MWGRLHSLGQDLAANQDDTMVRRVAVIGAGSSGLVATKCCLDEGLEPTCFERSEDIGGLWRFTDKADRGRVSVYRSVISNTSKEMSCFSDFPFPEDFPSFLPHNLFLEYFRMYAQHFQLLRHIRFKTTVISVRKRPDFATSGQWDVVTEAEGTQESHVFDAVMVCAGNFQQPHLPLASFPGIETRFRGQYFHSLEYKDAAAFQGKRVLVVGIGNTGCDIAVDMSRVAAKVFLSARSSTWVFSRVANHGFPWDMLNTTRFNHFLEWLLPSAVMKRIRIWKTNSWFNHEIYGLASAKSSNFNFIINEELPFCMLSGTIVLKSNVKEFTETSAVFEDGTTEENIDVVIFATGYNFSFSFLEESICNPLKNNSTLYKCIFPPQLERPTLAVIGLIKLTGSVMVGSEIQARWVTGVFAGAYKLPPSSKMMAEVSKKQLPVKRNLPEKQNSRLNFISYTSEIASCAGVKPSVLRLLLTNPRLALAVFFGPCTSYQYRLMGRGQWSGAGAAILTQWQRVLKPLRTRVLEDSASSYSWRWLGLLALPMALVVGFLLSKCPKLGWAPRAGLLF", "length": 564, "header": "tr|A0A8V0YMD8-1|A0A8V0YMD8_CHICK Isoform 1 of Flavin-containing monooxygenase OS=Gallus gallus OX=9031 GN=FMO4 PE=3 SV=1 CANONICAL=A0A8V0YMD8-1" }, "locus": { "chromosome": "8", "start_pos": 4805389, "end_pos": 4799890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033526.1", "url": "https://www.ensembl.org/id/ENSGALT00010033526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019768.1", "url": "https://www.ensembl.org/id/ENSGALP00010019768.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424393", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBP5-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmol", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVKKVAVIGAGVSGLGAIKCCLDEGLEPTCFEKRSDIGGLWKYEEISKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLLKHIQFQTKVCSIKKRPDFSSSGQWDVVVETGETQKTYIFDGIMVCSGHYTEKHFPLQDFEGISKFQGSCLHSWEYKHPNSFSGKRVVVIGIGNSGADVAGEISRVADQVFLSTRRGAWVWSRVWDHGNPMDASLFTRYNRAVQKFCPRYLINRQMEKKLNARFNHANFGLLPQHRILDHRTVFSDDLPSHIITGKVKIKTNVKTFTSTSAVFEDGTEENIDVVIFATGYKLAFPFLSDDSGILDSQYSMFKYVFPPELEKPTLAFIGIVQPAGAIIPTSELQSRWVVRVFTGLQKLPPKKAMMADIYRKHQADKDAIKNLKDSSRRVQFIDYMDEIASEIGVKPNLLSLLLWDTKLAKEIFYGPCTSYQYRLQGPGKWAGARAAILTQRERILKPLRTRVVKHSRASLSHLFWVKSVCVVSFFFISVLVIMHLTSV", "length": 538 }, "evidence": [ { "id": "A0A8V0YMD8", "url": "https://omabrowser.org/oma/group/A0A8V0YMD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X946-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Gm4847", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVKRIAVIGAGVSGLGAIKCCLEEGLEPTCFEKKSDIGGLWKYEEIPKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHHSKMMEYLRMYARHFGLMKHIQFQTNVCNIKKRPDFSSSGQWDVVVETEEMQKTYIFDGIMVCSGHYTEKYFPLQDFEGISKFQGSYLHTWEYKHPDNFVGKRVAVIGLGNSGADVAGEISRVADQVFLSTRQGAWIWNRVWDHGEPMDTTVFTRYNRAVQKICPRYIINRQMEKKLNGRFNHANYGLLPTHRILEQRTVLSDDLPNRIIIGKVKIKPNVKEFTSTSAIFEDGTKENIDVVIFATGYKLSFPFLSDDSGVLDNQYSMFKYVFPPELEKPTLAFIGILQPAGAILPTSELQSRWVVHVFKGIKKLPSRRAMIADINRKNHQIMAKGSKKILQDHRRVTFVDYMDEIASEIGVKPNLLSLLLWDTKLAKEVFCGPCTSYQYRLQGPGKWDGARAAILTQRERMLKPLRTRVVKQSHLSHLSWVKSACVVVFFFISVVVIMHITSH", "length": 537 }, "evidence": [ { "id": "A0A8V0YMD8", "url": "https://omabrowser.org/oma/group/A0A8V0YMD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" }, { "name": "trimethylamine monooxygenase activity", "id": "GO:0034899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" }, { "name": "N,N-dimethylaniline monooxygenase activity", "id": "GO:0004499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24468", "name": "", "equation": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUD7-1", "A0A8V0YMD8-1", "A0A8V0YK51-1", "A0A8V0YQ53-1" ], "evidence": [ { "id": "24468", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24468" } ] }, { "id": "31979", "name": "", "equation": "trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUD7-1", "A0A8V0YMD8-1", "A0A8V0YK51-1" ], "evidence": [ { "id": "31979", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31979" } ] }, { "id": "69819", "name": "", "equation": "hypotaurine + NADPH + O2 + H(+) = taurine + NADP(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUD7-1", "A0A8V0YMD8-1", "A0A8V0YK51-1" ], "evidence": [ { "id": "69819", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69819" } ] }, { "id": "74111", "name": "", "equation": "hypotaurine + NADH + O2 + H(+) = taurine + NAD(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMD8-1", "A0A8V0YK51-1" ], "evidence": [ { "id": "74111", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/74111" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YK51", "gene_name": "DM5L", "activity": [ { "ec_number": "1.6.3.1", "activity": "NADH + O2 + H(+) = H2O2 + NAD(+).", "evidence": [ { "id": "A0A8V0YK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK51" } ] }, { "ec_number": "1.14.13.8", "activity": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "A0A8V0YK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK51" } ] }, { "ec_number": "1.14.13.8", "activity": "", "evidence": [ { "id": "A0A8V0YK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK51" } ] }, { "ec_number": "1.6.3.1", "activity": "", "evidence": [ { "id": "A0A8V0YK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK51" } ] } ] }, { "uniprot_ac": "A0A8V0YMD8", "gene_name": "FMO4", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "A0A8V0YMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD8" } ] } ] }, { "uniprot_ac": "A0A8V0YQ53", "gene_name": "LOC100857694", "activity": [ { "ec_number": "1.6.3.1", "activity": "NADH + O2 + H(+) = H2O2 + NAD(+).", "evidence": [ { "id": "A0A8V0YQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ53" } ] }, { "ec_number": "1.14.13.8", "activity": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "A0A8V0YQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ53" } ] }, { "ec_number": "1.6.3.1", "activity": "", "evidence": [ { "id": "A0A8V0YQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ53" } ] }, { "ec_number": "1.14.13.8", "activity": "", "evidence": [ { "id": "A0A8V0YQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ53" } ] } ] }, { "uniprot_ac": "A0A8V0YUD7", "gene_name": "FMO3", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "A0A8V0YUD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD7" } ] }, { "ec_number": "1.14.13.148", "activity": "trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "A0A8V0YUD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD7" } ] }, { 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This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YME7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZDHHC18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7", "locus": { "chromosome": "23", "start_pos": 2165003, "end_pos": 2153713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014002", "url": "https://www.ensembl.org/id/ENSGALG00010014002" } ] } } ], "crossref": [ { "id": "A0A8V0YME7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YME7", "database": 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"evidence": [ { "id": "A0A8V0YN07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 38 member 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YN07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07/entry#names_and_taxonomy" } ] }, { "name": "sodium-coupled neutral amino acid transporter 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937299" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937299.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937299" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07", "locus": { "chromosome": "Z", "start_pos": 17424261, "end_pos": 17468558, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014167", "url": "https://www.ensembl.org/id/ENSGALG00010014167" } ] } } ], "crossref": [ { "id": "A0A8V0YN07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN07", "database": "AlphaFoldDB", "categories": [] }, { "id": "427139", "url": "https://www.ncbi.nlm.nih.gov/gene/427139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427139", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWFTPTE", "url": "https://omabrowser.org/oma/group/HWFTPTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGM1", "url": "https://www.orthodb.org/?gene=A0A8V0YGM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS6", "url": "https://www.orthodb.org/?gene=A0A8V0YMS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMT2", "url": "https://www.orthodb.org/?gene=A0A8V0YMT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN07", "url": "https://www.orthodb.org/?gene=A0A8V0YN07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-165159", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-165159", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-166208", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380972", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "68572", "url": "https://www.rhea-db.org/rhea/68572", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73011", "url": "https://www.rhea-db.org/rhea/73011", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73419", "url": "https://www.rhea-db.org/rhea/73419", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73423", "url": "https://www.rhea-db.org/rhea/73423", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDTKPLLIPVGGDECNYGIMNIQFSPEDFKCKRPFHVEPTNIVSASDDMQRVSDEASAMNKRIHYYSRLTSPSDKALVAPDHVLPAPDEIYVYSPLGTAFKVDSCTDGYGKNSSIVTIFVIWNTMMGTSILSIPWGIKQAGFTSGVILIVLMGILTLYCCYRVVKSRKMIPLTDTSNWEFPDVCKYYFGSFGQWSSLLFSMVSLVGAMVVYWVLMSNFLFNTGKFIYNFVHDINVTDIVPGTNGSNKVICPNAAGDHPPQNRSVMFSSGNSTGFQLFEEWWSKSQTVPFYLIAVLLPLLNLKSPSFFAKFNVLGTVSVIYLVLLVTVKAAHLGIHLEFNWFTENEFFVPEFRVLFPQLTGVLTLAFFIHNCVITLLQNNKNQENNVRDLSIAYFLVGLTYLYVGVIIFASFPSPPLSKECIEQNFLDNFPSNDIMSFIARIFLLFQMITVYPLLGYLARVQLLRQVFGTAYPSVFHVLALNIAIVGAGVAMARFYPNIGGIIRYSGATCGLAFVFVYPSLIYVISLHRAGQLTWPALIIHVFIILLGLANLIAQFLL", "length": 559, "header": "tr|A0A8V0YN07-1|A0A8V0YN07_CHICK Isoform 1 of Neutral amino acid transporter 9 OS=Gallus gallus OX=9031 GN=SLC38A9 PE=3 SV=1 CANONICAL=A0A8V0YN07-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM1/entry", "sequence": { "sequence": "MVEIKSWSCLELVSSRPFHVEPTNIVSASDDMQRVSDEASAMNKRIHYYSRLTSPSDKALVAPDHVLPAPDEIYVYSPLGTAFKVDSCTDGYGKNSSIVTIFVIWNTMMGTSILSIPWGIKQAGFTSGVILIVLMGILTLYCCYRVVKSRKMIPLTDTSNWEFPDVCKYYFGSFGQWSSLLFSMVSLVGAMVVYWVLMSNFLFNTGKFIYNFVHDINVTDIVPGTNGSNKVICPNAAGDHPPQNRSVMFSSGNSTGFQLFEEWWSKSQTVPFYLIAVLLPLLNLKSPSFFAKFNVLGTVSVIYLVLLVTVKAAHLGIHLEFNWFTENEFFVPEFRVLFPQLTGVLTLAFFIHNCVITLLQNNKNQENNVRDLSIAYFLVGLTYLYVGVIIFASFPSPPLSKECIEQNFLDNFPSNDIMSFIARIFLLFQMITVYPLLGYLARVQLLRQVFGTAYPSVFHVLALNIAIVGAGVAMARFYPNIGGIIRYSGATCGLAFVFVYPSLIYVISLHRAGQLTWPALIIHVFIILLGLANLIAQFLL", "length": 540, "header": "tr|A0A8V0YGM1-1|A0A8V0YN07_CHICK Computationally mapped isoform of Neutral amino acid transporter 9 OS=Gallus gallus OX=9031 GN=SLC38A9 PE=3 SV=1 CANONICAL=A0A8V0YN07-1" }, "locus": { "chromosome": "Z", "start_pos": 17459863, "end_pos": 17427046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034052.1", "url": "https://www.ensembl.org/id/ENSGALT00010034052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020014.1", "url": "https://www.ensembl.org/id/ENSGALP00010020014.1" } ] } }, { "isoform_ac": "A0A8V0YMS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS6/entry", "sequence": { "sequence": "MEEDTKPLLIPVGGDECNYGIMNIQFSPEDFKCKRPFHVEPTNIVSASDDMQRVSDEASAMNKRIHYYSRLTSPSDKALVAPDHVLPAPDEIYVYSPLGTAFKVDSCTDGYGKNSSIVTIFVIWNTMMGTSILSIPWGIKQAGFTSGVILIVLMGILTLYCCYRVVKSRKMIPLTDTSNWEFPDVCKYYFGSFGQWSSLLFSMVSLVGAMVVYWVLMSNFLFNTGKFIYNFVHDINVTDIVPGTNGSNKVICPNAAGDHPPQNRSVMFSSGNSTGFQLFEEWWSKSQTVPFYLIAVLLPLLNLKSPSFFAKFNVLEFRVLFPQLTGVLTLAFFIHNCVITLLQNNKNQENNVRDLSIAYFLVGLTYLYVGVIIFASFPSPPLSKECIEQNFLDNFPSNDIMSFIARIFLLFQMITVYPLLGYLARVQLLRQVFGTAYPSVFHVLALNIAIVGAGVAMARFYPNIGGIIRYSGATCGLAFVFVYPSLIYVISLHRAGQLTWPALIIHVFIILLGLANLIAQFLL", "length": 523, "header": "tr|A0A8V0YMS6-1|A0A8V0YMS6_CHICK Computationally mapped isoform of Neutral amino acid transporter 9 OS=Gallus gallus OX=9031 GN=SLC38A9 PE=3 SV=1 CANONICAL=A0A8V0YN07-1" }, "locus": { "chromosome": "Z", "start_pos": 17463544, "end_pos": 17427046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034060.1", "url": "https://www.ensembl.org/id/ENSGALT00010034060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020018.1", "url": "https://www.ensembl.org/id/ENSGALP00010020018.1" } ] } }, { "isoform_ac": "A0A8V0YMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT2/entry", "sequence": { "sequence": "MEEDTKPLLIPVGGDECNYGIMNIQFSPEDFKCKSFLFQYCRLPIEAEDGTVVYKLLYLWPLQQELLRPFHVEPTNIVSASDDMQRVSDEASAMNKRIHYYSRLTSPSDKALVAPDHVLPAPDEIYVYSPLGTAFKVDSCTDGYGKNSSIVTIFVIWNTMMGTSILSIPWGIKQAGFTSGVILIVLMGILTLYCCYRVVKSRKMIPLTDTSNWEFPDVCKYYFGSFGQWSSLLFSMVSLVGAMVVYWVLMSNFLFNTGKFIYNFVHDINVTDIVPGTNGSNKVICPNAAGDHPPQNRSVMFSSGNSTGFQLFEEWWSKSQTVPFYLIAVLLPLLNLKSPSFFAKFNVLGTVSVIYLVLLVTVKAAHLGIHLEFNWFTENEFFVPEFRVLFPQLTGVLTLAFFIHNCVITLLQNNKNQENNVRDLSIAYFLVGLTYLYVGVIIFASFPSPPLSKECIEQNFLDNFPSNDIMSFIARIFLLFQMITVYPLLGYLARVQLLRQVFGTAYPSVFHVLALNIAIVGAGVAMARFYPNIGGIIRYSGATCGLAFVFVYPSLIYVISLHRAGQLTWPALIIHVFIILLGLANLIAQFLL", "length": 592, "header": "tr|A0A8V0YMT2-1|A0A8V0YMT2_CHICK Computationally mapped isoform of Neutral amino acid transporter 9 OS=Gallus gallus OX=9031 GN=SLC38A9 PE=3 SV=1 CANONICAL=A0A8V0YN07-1" }, "locus": { "chromosome": "Z", "start_pos": 17463544, "end_pos": 17427046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034069.1", "url": "https://www.ensembl.org/id/ENSGALT00010034069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020023.1", "url": "https://www.ensembl.org/id/ENSGALP00010020023.1" } ] } }, { "isoform_ac": "A0A8V0YN07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07/entry", "sequence": { "sequence": "MEEDTKPLLIPVGGDECNYGIMNIQFSPEDFKCKRPFHVEPTNIVSASDDMQRVSDEASAMNKRIHYYSRLTSPSDKALVAPDHVLPAPDEIYVYSPLGTAFKVDSCTDGYGKNSSIVTIFVIWNTMMGTSILSIPWGIKQAGFTSGVILIVLMGILTLYCCYRVVKSRKMIPLTDTSNWEFPDVCKYYFGSFGQWSSLLFSMVSLVGAMVVYWVLMSNFLFNTGKFIYNFVHDINVTDIVPGTNGSNKVICPNAAGDHPPQNRSVMFSSGNSTGFQLFEEWWSKSQTVPFYLIAVLLPLLNLKSPSFFAKFNVLGTVSVIYLVLLVTVKAAHLGIHLEFNWFTENEFFVPEFRVLFPQLTGVLTLAFFIHNCVITLLQNNKNQENNVRDLSIAYFLVGLTYLYVGVIIFASFPSPPLSKECIEQNFLDNFPSNDIMSFIARIFLLFQMITVYPLLGYLARVQLLRQVFGTAYPSVFHVLALNIAIVGAGVAMARFYPNIGGIIRYSGATCGLAFVFVYPSLIYVISLHRAGQLTWPALIIHVFIILLGLANLIAQFLL", "length": 559, "header": "tr|A0A8V0YN07-1|A0A8V0YN07_CHICK Isoform 1 of Neutral amino acid transporter 9 OS=Gallus gallus OX=9031 GN=SLC38A9 PE=3 SV=1 CANONICAL=A0A8V0YN07-1" }, "locus": { "chromosome": "Z", "start_pos": 17463544, "end_pos": 17427046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034066.1", "url": "https://www.ensembl.org/id/ENSGALT00010034066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020021.1", "url": "https://www.ensembl.org/id/ENSGALP00010020021.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427139", "resource": "KEGG Pathway" }, { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-GGA-165159", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-165159", "resource": "Reactome", "description": "MTOR signalling" }, { "id": "R-GGA-166208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166208", "resource": "Reactome", "description": "mTORC1-mediated signalling" }, { "id": "R-GGA-380972", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "resource": "Reactome", "description": "Energy dependent regulation of mTOR by LKB1-AMPK" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MJ94-1", "protein_name": "Neutral amino acid transporter 9", "gene_name": "SLC38A9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVTVGEHPDTYPEVELMSHMVVLFLVFLRSSHTVFHSGYTNLHSHQRTDFFSAYSLRKMANMDSDSRHLLIPEGDHEINPGPMNIQFDSSDIRSKRPFYIEPTNIVSVNDVIQRVSDHASAMNKRIHYYSRLTAPADRALIAPDHVVPAPEECYVYSPLGSAYKLQCYTEGYGKNTSLVTIFMIWNTMLGTSILSIPWGIKQAGFTTGMCVIMLMGLLTLYCCYRVVKSRSMISSVDTTTWEYPDVCRYYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDSIPSTNDSNPVICPSARSGGHPDNSSVIFYASNSELQQFEKWWNKSKTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTWKAIRLGFHLEFHWFMPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIITLLKNNKNQENNVRDLSIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDILSFIARIFLLFQMMTVYPLLGYLARVQLLGHVFGDVYPSIFHVLIFNLFIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEDRLTWPKVIFHVFIIILGLANLIVQFFM", "length": 619 }, "evidence": [ { "id": "A0A8V0YN07", "url": "https://omabrowser.org/oma/group/A0A8V0YN07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q08BA4-1", "protein_name": "Neutral amino acid transporter 9", "gene_name": "slc38a9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEDSKPLLGSVPTGDYYTDSLDPKQRRPFHVEPRNIVGEDVQERVSAEAAVLSSRVHYYSRLTGSSDRLLAPPDHVIPSHEDIYIYSPLGTAFKVQGGDSPIKNPSIVTIFAIWNTMMGTSILSIPWGIKQAGFTLGIIIIVLMGLLTLYCCYRVLKSTKSIPYVDTSDWEFPDVCKYYFGGFGKWSSLVFSLVSLIGAMVVYWVLMSNFLFNTGKFIFNYVHNVNTSDAFGTNGTERVICPYPDVDPHGNSSTSLYSGSDNSTGLEFDHWWSKTNTIPFYLILLLLPLLNFRSASFFARFTFLGTISVIYLIFLVTYKAIQLGFHLEFHWFDSSMFFVPEFRTLFPQLSGVLTLAFFIHNCIITLMKNNKHQENNVRDLSLAYLLVGLTYLYVGVLIFAAFPSPPLSKECIEPNFLDNFPSSDILVFVARTFLLFQMTTVYPLLGYLVRVQLMGQIFGNHYPGFLHVFVLNVFVVGAGVLMARFYPNIGSIIRYSGALCGLALVFVLPSLIHMVSLKRRGELRWTSTLFHGFLILLGVANLLGQFFM", "length": 549 }, "evidence": [ { "id": "A0A8V0YN07", "url": "https://omabrowser.org/oma/group/A0A8V0YN07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3B8Q3-1", "protein_name": "Neutral amino acid transporter 9", "gene_name": "Slc38a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANVDSDSRHLISEVEHEVNPGPMNIQFDSSDLRSKRPFYIEPTNIVNVNDVIQKVSDHAAAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLKSYTEGYRKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIVLMGLLTLYCCYRVVKSRSMIVTSDTTTWEYPDVCKHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTVLSTNNSSPVICPSAGSGHPDNSSMIFYNSDTEVRLFERWWDKSKTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFIVTLKAIRLGFHLEFHWFAPTEFFVPEIRAQFPQLTGVLTLAFFIHNCIITLLKNNKNQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLPKDCIEQNFLDNFPSSDTLSFIARICLLFQMMTVYPLLGYLARVQLLGHIFGDIYPSIFHVLILNLIIVGAGVTMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYILSQHQEERLTWPKLVFHIIIIILGLANLIAQFFM", "length": 559 }, "evidence": [ { "id": "A0A8V0YN07", "url": "https://omabrowser.org/oma/group/A0A8V0YN07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGD6-1", "protein_name": "Neutral amino acid transporter 9", "gene_name": "Slc38a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVDGDSRHLLSEVEHEVSPGPMNIQFDSSDLRSKRPFYIEPTNIVNVNDVIQRVSDHAAAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLKSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIVLMGLLTLYCCYRVVKSRSTISTSDTSTWEYPDVCKHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTVLSTNNSNPVICPNAGSGGRPDNSSMIFYNNNTEVQLFEKWWDKSRTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFVVTLKAVRLGFHLEFHWFVPTEFFVPEIRAQFPQLMGVLTLAFFIHNCIITLLKNNKNQENNVRDLCIAYMLVTLTYLYIGILVFASFPSPPLPKDCIEQNFLDNFPSSDILSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDIYPSIFHVLILNLVIVGAGVTMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKLVFHVIIIILGLANLIAQFFM", "length": 560 }, "evidence": [ { "id": "A0A8V0YN07", "url": "https://omabrowser.org/oma/group/A0A8V0YN07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBW4-1", "protein_name": "Neutral amino acid transporter 9", "gene_name": "SLC38A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANMNSDSRHLGTSEVDHERDPGPMNIQFEPSDLRSKRPFCIEPTNIVNVNHVIQRVSDHASAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLQSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYCCYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWWDKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIITLLKNNKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDIYPSIFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKLIFHVFIIILGVANLIVQFFM", "length": 561 }, "evidence": [ { "id": "A0A8V0YN07", "url": "https://omabrowser.org/oma/group/A0A8V0YN07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07" } ], "pmid": "" }, { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN07" } ], "pmid": "" }, { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": 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"ENSGALP00010020158.1", "url": "https://www.ensembl.org/id/ENSGALP00010020158.1" } ] } }, { "isoform_ac": "A0A8V0YQ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64/entry", "sequence": { "sequence": "MSTGEVERLSTDLGGAAGDEEEEWLYGDENEAERPEEEKTSAPPPPGNEEEAAENGVVKTKVTEAEDDSDSDSDDDEDDVQVTIGDIKTGAPQFSYGAAPVNLNIKTGGRVYGSSAGVKVKGVDLDAPGNINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEILPVTSATNKITVQQGRTGNLEKELAVQSTKADFTSPPALFKSGIPTNRRLSGAIDVIGQTITISRVEGRRRANENSNIQFDILQVLSERSNPEVDNFTKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGGPPPSLIPTIESGHSSGYDSRSVRAFSYGSGSAPSWSSLMDSSKQWDYYARREKDRERDRDRSRDRDRDRDRDRDRERTRDRERDRDHSPSSSTFNSDEERYRYRDYAERGYDRHRTSREKDDRHRERRHREKEDTRHKSSRSNSRRRHDSEEGDSHRRHKHKKSKRSKEGKEASSEPAPEQENTEAAPAE", "length": 527, "header": "tr|A0A8V0YQ64-1|A0A8V0YQ64_CHICK Isoform 1 of Pre-mRNA 3'-end-processing factor FIP1 OS=Gallus gallus OX=9031 GN=FIP1L1 PE=1 SV=1 CANONICAL=A0A8V0YQ64-1" }, "locus": { "chromosome": "4", "start_pos": 65275766, "end_pos": 65238639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034329.1", "url": "https://www.ensembl.org/id/ENSGALT00010034329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020163.1", "url": "https://www.ensembl.org/id/ENSGALP00010020163.1" } ] } }, { "isoform_ac": "A0A8V0YV73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV73/entry", "sequence": { "sequence": "MSTGEVERLSTDLGGAAGDEEEEWLYGDENEAERPEEEKTSAPPPPGNEEEAAENGVVKTKVTEAEDDSDSDSDDDEDDVQVTIGDIKTGAPQFSYGAAPVNLNIKTGGRVYGSSGVKVKGVDLDAPGNINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEILPVTSATNKITAEDNAMEVTSSAEILDGRYHLFKVNYSKLLLVALIYVEYCYPYQHRPIEEQLEKTQPLFQTLILHW", "length": 261, "header": "tr|A0A8V0YV73-1|A0A8V0YQ64_CHICK Computationally mapped isoform of Pre-mRNA 3'-end-processing factor FIP1 OS=Gallus gallus OX=9031 GN=FIP1L1 PE=1 SV=1 CANONICAL=A0A8V0YQ64-1" }, "locus": { "chromosome": "4", "start_pos": 65275766, "end_pos": 65265006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034311.1", "url": "https://www.ensembl.org/id/ENSGALT00010034311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020156.1", "url": "https://www.ensembl.org/id/ENSGALP00010020156.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-77595", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77595", "resource": "Reactome", "description": "Processing of Intronless Pre-mRNAs" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64" } ], "pmid": "" }, { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ64" }, { "id": "PF05182", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA polyadenylation factor Fip1", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 180, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 309 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPY7-1", "uniprot_ac": "A0A8V0YPY7", "uniprot_id": "A0A8V0YPY7_CHICK", "mass": { "chemical_mass": 86994.0, "monoisotopic_mass": 86994.0 }, "refseq": { "ac": "NP_990723", "name": "myosin light chain kinase 2, skeletal/cardiac muscle", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" }, "gene_names": [ { "name": "MYLK2", "type": "recommended", "evidence": [ { "id": "A0A8V0YPY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ] }, { "name": "MYLK2", "type": "synonym", "evidence": [ { "id": "NP_990723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" } ] } ], "protein_names": [ { "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "type": "recommended", "evidence": [ { "id": "A0A8V0YPY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.18", "type": "synonym", "evidence": [ { "id": "A0A8V0YPY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7/entry#names_and_taxonomy" } ] }, { "name": "Gallus domesticus skeletal muscle", "type": "synonym", "evidence": [ { "id": "NP_990723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" } ] }, { "name": "myosin light chain kinase 2, skeletal muscle", "type": "synonym", "evidence": [ { "id": "NP_990723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" } ] }, { "name": "myosin light chain kinase 2, skeletal/cardiac muscle", "type": "synonym", "evidence": [ { "id": "NP_990723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: M81787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992437 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On Oct 25, 2021 this sequence version replaced NP_990723.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723" } ] }, { "annotation": "Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH72#function" }, { "database": "UniProtKB", "id": "ARBA00045834", "url": "https://www.uniprot.org/uniprotkb/ARBA00045834#function" }, { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7", "locus": { "chromosome": "20", "start_pos": 10400968, "end_pos": 10393778, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013029", "url": "https://www.ensembl.org/id/ENSGALG00010013029" } ] } } ], "crossref": [ { "id": "A0A8V0YPY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396356", "url": "https://www.ncbi.nlm.nih.gov/gene/396356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396356", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPAACQR", "url": "https://omabrowser.org/oma/group/CPAACQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH72", "url": "https://www.orthodb.org/?gene=A0A8V0YH72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPY7", "url": "https://www.orthodb.org/?gene=A0A8V0YPY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YH72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQPEVPGSTADTGGSGSTAPPGTESSTAQPAPTVATNAVQAQNRGKEEPMEKTVGAAGEPHGGTAEPAQEKVPTAAGKEEPGKEVAPGAAAEAQGAEREKAVPEGGKAEPEQEKVPNAAPHWDGGEKGAAKEGASAAETNRGKEEPAKEKAPTGESRGETAEPTQGKGSAAAGAQEEPPKENAPGAPGAEAGGEAEPAKKASAAVEAERGKAEPAGSVPAAAPAHGEGEPAKEQPAAVKAEDGGKNAAKAKKSSAAKQPAKEKAPAAAKDGGKKPTKVEKIAAVTKDGGKETAKEKATAPAKEKATVAAQKPPAAVKAEDGGREPTEKAPAAAGAQGEGEKEANAEQTNKEQPPRGSEPTRPTLMQSLSCPATCQREEQPGPEVAAMETIPEETPMAPAGEEPTPAQGDLQPPEQPIPAGSTAVPQERTLPGAEEQPQVGSEAPGHAEQPGPGATGQPAATVAEPPPSPYLTPDFGKEDPFEILDDVPPPPAPFAHRIITLRTGSVSSQYNLSSKEILGGGKFGEVHTCTEKQTGLKLAAKVIRKQGAKDKEMVLLEIDVMNQLNHRNLIQLYDAIETPREIILFMEFVEGGELFERIIDDDYHLTEVDCMVFVRQICEGIRFMHHMRVLHLDLKPENILCVAATGHMVKIIDFGLARRYNPEEKLKVNFGTPEFLSPEVVNYEQVSYSTDMWSMGVITYMLLSGLSPFLGDNDTETLNNVLAANWYFDEETFESVSDEAKDFVSNLIIKEKSARMSAGQCLQHPWLTNLAEKAKRCNRRLKSQVMLKKYVMRRRWKKNFIGVCAANRFKKITSSGSLTALGV", "length": 824, "header": "tr|A0A8V0YPY7-1|A0A8V0YPY7_CHICK Isoform 1 of Myosin light chain kinase 2, skeletal/cardiac muscle OS=Gallus gallus OX=9031 GN=MYLK2 PE=3 SV=1 CANONICAL=A0A8V0YPY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH72/entry", "sequence": { "sequence": "MEQPEVPGSTADTGGSGSTAPPGTESSTAQPAPTVATNAVQAQNRGKEEPMEKTVGAAGEPHGGTAEPAQEKVPTAAGKEEPGKEVAPGAAAEAQGAEREKAVPEGGKAEPEQEKVPNAAPHWDGGEKGAAKEGASAAETNRGKEEPAKEKAPTGESRGETAEPTQGKGSAAAGAQEEPPKENAPGAPGAEAGGEAEPAKKASAAVEAERGKAEPAGSVPAAAPAHGEGEPAKEQPAAVKAEDGGKNAAKAKKSSAAKQPAKEKAPAAAGAQGEGEKEANAEQTNKEQPPRGSEPTRPTLMQSLSCPATCQREEQPGPEVAAMETIPEETPMAPAGEEPTPAQGDLQPPEQPIPAGSTAVPQERTLPGAEEQPQVGSEAPGHAEQPGPGATGQPAATVAEPPPSPYLTPDFGKEDPFEILDDVPPPPAPFAHRIITLRTGSVSSQYNLSSKEILGGGKFGEVHTCTEKQTGLKLAAKVIRKQGAKDKEMVLLEIDVMNQLNHRNLIQLYDAIETPREIILFMEFVEGGELFERIIDDDYHLTEVDCMVFVRQICEGIRFMHHMRVLHLDLKPENILCVAATGHMVKIIDFGLARRYNPEEKLKVNFGTPEFLSPEVVNYEQVSYSTDMWSMGVITYMLLSGLSPFLGDNDTETLNNVLAANWYFDEETFESVSDEAKDFVSNLIIKEKSARMSAGQCLQHPWLTNLAEKAKRCNRRLKSQVMLKKYVMRRRWKKNFIGVCAANRFKKITSSGSLTALGV", "length": 759, "header": "tr|A0A8V0YH72-1|A0A8V0YPY7_CHICK Computationally mapped isoform of Myosin light chain kinase 2, skeletal/cardiac muscle OS=Gallus gallus OX=9031 GN=MYLK2 PE=3 SV=1 CANONICAL=A0A8V0YPY7-1" }, "locus": { "chromosome": "20", "start_pos": 10399761, "end_pos": 10394744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031249.1", "url": "https://www.ensembl.org/id/ENSGALT00010031249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018213.1", "url": "https://www.ensembl.org/id/ENSGALP00010018213.1" } ] } }, { "isoform_ac": "A0A8V0YPY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7/entry", "sequence": { "sequence": "MEQPEVPGSTADTGGSGSTAPPGTESSTAQPAPTVATNAVQAQNRGKEEPMEKTVGAAGEPHGGTAEPAQEKVPTAAGKEEPGKEVAPGAAAEAQGAEREKAVPEGGKAEPEQEKVPNAAPHWDGGEKGAAKEGASAAETNRGKEEPAKEKAPTGESRGETAEPTQGKGSAAAGAQEEPPKENAPGAPGAEAGGEAEPAKKASAAVEAERGKAEPAGSVPAAAPAHGEGEPAKEQPAAVKAEDGGKNAAKAKKSSAAKQPAKEKAPAAAKDGGKKPTKVEKIAAVTKDGGKETAKEKATAPAKEKATVAAQKPPAAVKAEDGGREPTEKAPAAAGAQGEGEKEANAEQTNKEQPPRGSEPTRPTLMQSLSCPATCQREEQPGPEVAAMETIPEETPMAPAGEEPTPAQGDLQPPEQPIPAGSTAVPQERTLPGAEEQPQVGSEAPGHAEQPGPGATGQPAATVAEPPPSPYLTPDFGKEDPFEILDDVPPPPAPFAHRIITLRTGSVSSQYNLSSKEILGGGKFGEVHTCTEKQTGLKLAAKVIRKQGAKDKEMVLLEIDVMNQLNHRNLIQLYDAIETPREIILFMEFVEGGELFERIIDDDYHLTEVDCMVFVRQICEGIRFMHHMRVLHLDLKPENILCVAATGHMVKIIDFGLARRYNPEEKLKVNFGTPEFLSPEVVNYEQVSYSTDMWSMGVITYMLLSGLSPFLGDNDTETLNNVLAANWYFDEETFESVSDEAKDFVSNLIIKEKSARMSAGQCLQHPWLTNLAEKAKRCNRRLKSQVMLKKYVMRRRWKKNFIGVCAANRFKKITSSGSLTALGV", "length": 824, "header": "tr|A0A8V0YPY7-1|A0A8V0YPY7_CHICK Isoform 1 of Myosin light chain kinase 2, skeletal/cardiac muscle OS=Gallus gallus OX=9031 GN=MYLK2 PE=3 SV=1 CANONICAL=A0A8V0YPY7-1" }, "locus": { "chromosome": "20", "start_pos": 10399761, "end_pos": 10394744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031245.1", "url": "https://www.ensembl.org/id/ENSGALT00010031245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018210.1", "url": "https://www.ensembl.org/id/ENSGALP00010018210.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 405, "start_aa": "Thr", "end_pos": 405, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr405", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396356", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" }, { "name": "myosin light chain kinase activity", "id": "GO:0004687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, 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"A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" }, { "name": "regulation of muscle filament sliding", "id": "GO:0032971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY7" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", 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"annotation": "Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD5#function" }, { "database": "UniProtKB", "id": "ARBA00046222", "url": "https://www.uniprot.org/uniprotkb/ARBA00046222#function" }, { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53#function" }, { "database": "UniProtKB", "id": "A0A8V0YM59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM59#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NLN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53", "locus": { "chromosome": "Z", "start_pos": 21243665, "end_pos": 21204865, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012346", "url": "https://www.ensembl.org/id/ENSGALG00010012346" } ] } } ], "crossref": [ { "id": "A0A8V0YM53", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM53", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06455", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06455", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHD5", "url": "https://www.orthodb.org/?gene=A0A8V0YHD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM53", "url": "https://www.orthodb.org/?gene=A0A8V0YM53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM59", "url": "https://www.orthodb.org/?gene=A0A8V0YM59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11804:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11804:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEGQSDKMASDTEGHMEQRATCIVFHKADIVRFLYGNTELSDLSIGPRLLLRMTLGAEITNQLKASSYIAPGRNLLRWDLSPEQIRTRTEELIRKTKHVYDIVGKLNIEEVTHENTVRALADIEVEYAVERSMLDFPQHVSPDKEVRLASTEADKKLSNFDVEMSMREDVFQKIVYLQQTCNLENIKPETKRYLDKSVQVGKRNGLHLPKEVQHEIMTMKKKLSELCIDFNKNLNEENTFLVFSKEELEGLPEDFIKSLEKTEEDKYKITLKYPHYFPVMKKCCISETRRKMESAFNTRCKEENTKILQQLLPLRAKVAELLGYNTHANFVLEVNTAKSTENVTTFLDDLSKKLKPLVEKEREFILDLKKKECQERNCDYDGRINAWDLHYYMNKTEELKYSIDQEKLKEYFPIEAVTEGLLSIYQKLLGLVFEQVESAHVWHDSVTLYTVKDNSTGETLGQFYLDLYPREGKYGHAACFGLQPGCLLSDGSRMMSVAALVTNFTKPGSDRPSLLRHDEVKTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMFENWVWEKEPLQQMSRHYKDESHVADALLEKLAASRLANTGLLTLRQIVLSKVDQALHTKPSVDPGDEYAKYCMEILGIPATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDIFYSCFKQEGIMNPKAGMKYRNLILKPGGSLDGMDMLQNFLERKPSQRAFLLSKGLCVQ", "length": 734, "header": "tr|A0A8V0YM53-1|A0A8V0YM53_CHICK Isoform 1 of Neurolysin, mitochondrial OS=Gallus gallus OX=9031 GN=NLN PE=1 SV=1 CANONICAL=A0A8V0YM53-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD5/entry", "sequence": { "sequence": "MTLGAEITNQLKASSYIAPGRNLLRWDLSPEQIRTRTEELIRKTKHVYDIVGKLNIEEVTHENTVRALADIEVEYAVERSMLDFPQHVSPDKEVRLASTEADKKLSNFDVEMSMREDVFQKIVYLQQTCNLENIKPETKRYLDKSVQVGKRNGLHLPKEVQHEIMTMKKKLSELCIDFNKNLNEENTFLVFSKEELEGLPEDFIKSLEKTEEDKYKITLKYPHYFPVMKKCCISETRRKMESAFNTRCKEENTKILQQLLPLRAKVAELLGYNTHANFVLEVNTAKSTENVTTFLDDLSKKLKPLVEKEREFILDLKKKECQERNCDYDGRINAWDLHYYMNKTEGLLSIYQKLLGLVFEQVESAHVWHDSVTLYTVKDNSTGETLGQFYLDLYPREGKYGHAACFGLQPGCLLSDGSRMMSVAALVTNFTKPGSDRPSLLRHDEVKTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMFENWVWEKEPLQQMSRHYKDESHVADALLEKLAASRLANTGLLTLRQIVLSKVDQALHTKPSVDPGDEYAKYCMEILGIPATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDIFYSCFKQEGIMNPKAGMKYRNLILKPGGSLDGMDMLQNFLERKPSQRAFLLSKGLCVQ", "length": 658, "header": "tr|A0A8V0YHD5-1|A0A8V0YM53_CHICK Computationally mapped isoform of Neurolysin, mitochondrial OS=Gallus gallus OX=9031 GN=NLN PE=1 SV=1 CANONICAL=A0A8V0YM53-1" }, "locus": { "chromosome": "Z", "start_pos": 21243287, "end_pos": 21217635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029559.1", "url": "https://www.ensembl.org/id/ENSGALT00010029559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017186.1", "url": "https://www.ensembl.org/id/ENSGALP00010017186.1" } ] } }, { "isoform_ac": "A0A8V0YM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53/entry", "sequence": { "sequence": "MAAEGQSDKMASDTEGHMEQRATCIVFHKADIVRFLYGNTELSDLSIGPRLLLRMTLGAEITNQLKASSYIAPGRNLLRWDLSPEQIRTRTEELIRKTKHVYDIVGKLNIEEVTHENTVRALADIEVEYAVERSMLDFPQHVSPDKEVRLASTEADKKLSNFDVEMSMREDVFQKIVYLQQTCNLENIKPETKRYLDKSVQVGKRNGLHLPKEVQHEIMTMKKKLSELCIDFNKNLNEENTFLVFSKEELEGLPEDFIKSLEKTEEDKYKITLKYPHYFPVMKKCCISETRRKMESAFNTRCKEENTKILQQLLPLRAKVAELLGYNTHANFVLEVNTAKSTENVTTFLDDLSKKLKPLVEKEREFILDLKKKECQERNCDYDGRINAWDLHYYMNKTEELKYSIDQEKLKEYFPIEAVTEGLLSIYQKLLGLVFEQVESAHVWHDSVTLYTVKDNSTGETLGQFYLDLYPREGKYGHAACFGLQPGCLLSDGSRMMSVAALVTNFTKPGSDRPSLLRHDEVKTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMFENWVWEKEPLQQMSRHYKDESHVADALLEKLAASRLANTGLLTLRQIVLSKVDQALHTKPSVDPGDEYAKYCMEILGIPATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDIFYSCFKQEGIMNPKAGMKYRNLILKPGGSLDGMDMLQNFLERKPSQRAFLLSKGLCVQ", "length": 734, "header": "tr|A0A8V0YM53-1|A0A8V0YM53_CHICK Isoform 1 of Neurolysin, mitochondrial OS=Gallus gallus OX=9031 GN=NLN PE=1 SV=1 CANONICAL=A0A8V0YM53-1" }, "locus": { "chromosome": "Z", "start_pos": 21243287, "end_pos": 21211184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029553.1", "url": "https://www.ensembl.org/id/ENSGALT00010029553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017179.1", "url": "https://www.ensembl.org/id/ENSGALP00010017179.1" } ] } }, { "isoform_ac": "A0A8V0YM59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM59/entry", "sequence": { "sequence": "MLALRAARRSIGPRLLLRMTLGAEITNQLKASSYIAPGRNLLRWDLSPEQIRTRTEELIRKTKHVYDIVGKLNIEEVTHENTVRALADIEVEYAVERSMLDFPQHVSPDKEVRLASTEADKKLSNFDVEMSMREDVFQKIVYLQQTCNLENIKPETKRYLDKSVQVGKRNGLHLPKEVQHEIMTMKKKLSELCIDFNKNLNEENTFLVFSKEELEGLPEDFIKSLEKTEEDKYKITLKYPHYFPVMKKCCISETRRKMESAFNTRCKEENTKILQQLLPLRAKVAELLGYNTHANFVLEVNTAKSTENVTTFLDDLSKKLKPLVEKEREFILDLKKKECQERNCDYDGRINAWDLHYYMNKTEELKYSIDQEKLKEYFPIEAVTEGLLSIYQKLLGLVFEQVESAHVWHDSVTLYTVKDNSTGETLGQFYLDLYPREGKYGHAACFGLQPGCLLSDGSRMMSVAALVTNFTKPGSDRPSLLRHDEVKTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMFENWVWEKEPLQQMSRHYKDESHVADALLEKLAASRLANTGLLTLRQIVLSKVDQALHTKPSVDPGDEYAKYCMEILGIPATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDIFYSCFKQEGIMNPKNRRVGKDLQDHLSAILPSPLLPQATKPYRVAPHPDAS", "length": 691, "header": "tr|A0A8V0YM59-1|A0A8V0YM59_CHICK Computationally mapped isoform of Neurolysin, mitochondrial OS=Gallus gallus OX=9031 GN=NLN PE=1 SV=1 CANONICAL=A0A8V0YM53-1" }, "locus": { "chromosome": "Z", "start_pos": 21240120, "end_pos": 21205027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029557.1", "url": "https://www.ensembl.org/id/ENSGALT00010029557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017184.1", "url": "https://www.ensembl.org/id/ENSGALP00010017184.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 643, "start_aa": "Thr", "end_pos": 643, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" }, { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8940959", "name": "Neurolysin degrades neurotensin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-GGA-388915" ], "output_participant_list": [ "R-GGA-8940947", "R-GGA-8940954" ], "enzyme_list": [ "A0A8V0YM53-1" ], "evidence": [ { "id": "R-GGA-8940959", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8940959" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-388915", "participant_name": "NTS [extracellular region]", "crossref": [ { "id": "A0A8V0YAJ1", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010011352", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010015458", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010027155", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-8940947", "participant_name": "NTS [extracellular region]", "crossref": [ { "id": "A0A8V0YAJ1", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010015458", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010027155", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010011352", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-8940954", "participant_name": "NTS [extracellular region]", "crossref": [ { "id": "ENSGALP00010015458", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YAJ1", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010027155", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010011352", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YM53", "gene_name": "NLN", "activity": [ { "ec_number": "3.4.24.16", "activity": "Preferential cleavage in neurotensin: 10-Pro-|-Tyr-11.", "evidence": [ { "id": "A0A8V0YM53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ] }, { "ec_number": "3.4.24.16", "activity": "", "evidence": [ { "id": "A0A8V0YM53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM53" }, { "id": "PF01432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M3A/M3B catalytic", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 729, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.24.16", "ec_name": "Preferential cleavage in neurotensin: 10-Pro-|-Tyr-11.", "evidence": [ { "id": "3.4.24.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.24.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 643 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 344, "end_pos": 346 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 505, "end_pos": 507 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQKPSKIIKSNDPPNTGPLPLFFPKASHPPPYKTCFLCSPFRFLCDHQIPHPDLDCPSTVYLSNLPSPSAPSVGSLQGIGVLRVGFDGYLFQDLRRHHTMEINTKRNFLSFAVLLVHCMIRDASCEKGNTSPLHFTHFFYNATIYENSAPKTYVESYVKMGVYKTDPEWDIRYRIASGDSSGLFKTEEHVIGDFCFLRIRTRSSNTALLNREVKDSYMLIIKATENTFAYEAWAKVLIHILDRNDLKPLFSPPSYKVSIREDTPLKTVVSTLSATDADAGQNAEFYYALNTKSDLFTIHPTTGAVVTTGRLNSTHRGRHHLQVLAVDRMRKIMEGNGFGNLASLTIQVEPSAKKPPSISSVKVAPPDSAEDLLYTSLSVESGDSETGIDSVDFVDGDPGRHFAVIRSYFGSTEFMIVAIKEIDWLLHPFGFNLSLQAKDKSKPPLFSPVRVIHIPPSKYVSARFEKEVYRVQLSEFSPPGSQVAMVKITPVLPNLKYVLRPTPDSTHFKINPHTGLITTVRAMDFHEQSNFQLEVATTNSHTSATVVIDIIDCNNHAPSFSQSSYRGAFDENAPPGTSVLTVRATDEDEGDNGFVTYTIANQKSVPFVIDPYSGIISTSKSLDYELMQRWYHLRVWASDWGSPFRHETEVYVSLMLSNVNDNAPVFEKASCSGSIPRDFPVGNPVATVSAIDSDELQRIKYEIKSGNELRHFELNPISGVISLRISLRDLPSEQPLFYSLKITATDGENYALPTSVNITVVSQGLPVKMQCEETGVLKQLTETIIHSIESQSEGQGQDDETTLNLHLINHNAPKFDDSFPRSIDIIENVPINSTIADLSAVDPDTGFNGKLVYVISDGNVDSCFTIDLELGLLQILSPLDHERTSFYILNITVYDLGTPQKSSWKLLAVNVLDTNDNTPRFPQGAYWVAIPENVVTGTTIAQLKAEDADTDDNGRVKYSLLTPTDKFAINSVTGEVTVIGALDRELWPYYALKIKARDQPKTGYQLFSVTDLIVTLEDVNDNDPHCLPALNNVKVPEDLPVGTILLFLEAFDPDAGSGGEVRYSLVNDEEMMFHIDKLTGALRLEKELDYEKKDSYNLTVQVRDSGKPVSRSSLCHLEVNVLDVNENLYPPRFASFVFKGWVQENSPEGTSVMMVTAKDIDKGKDGEVQYFLREGTGLSVFSIEKDTGTIRTIGPLDREGTSHYWLTVLALDLGTVPLSSATEIYIEVTDTNDNPPQMSRPVYYASVMENSPPNTSVLQLDALDPDSSSEGKLTFHILTGNPQGLFAINLVTGLISTTSRQLDREYKAEHILEVAVSDNGDPALKSTSRVVIQVLDANDNPPSFPHKLFMVQLPEREASETPLPVYRLIASDRDQGQNSQVTYTIEEEEEGIFTINPTTGMVLSRKAFPASEYNILTVKATDGGSPPLSSHVRLHISWVVRPGPSSEPLAFDEPHFNFAVMETDPVNHMVGVISIEMGPSQVWFNITGGDDDMDFDIEKSTGSMVIARALDARKKSSYNLTVEVTDGSTTIKTQAFIHVIDINQHRPQFLESHYEMRIPEDTPSGREILQVSATDKDKGKGLIYTIHGSMDPRSTRLFQLDPSSGVLTTAEGFSSQPMPQHTLTVMVRDQEVPIKRNFVRVIIHVENCNLHPPQFSSIHYEAETLDSAAVGTEIVQVRALDQDQGANAEIHYSLQAGNGEGFFSIDPHSGIITVAQKLDPSKQERFTLIVKAEDQGFPQLKDSATVHIRIRPSDQTPPKFPEAEYITEISESAAVGSPLIQVSTSSSSPVSYEIKDGNGDGVFSMNYQSGLISTQKNLDFEQVSFYQLKVRGTNMAGAFMDTMVLIYVIDENDNVPIFVKPAFIGWIMENAPPQSMVLDESNSPLVTHATDADQDSNALLVYEILEPEALKYFTVDPSTGTLTSRADIDYELTPVFHFSVHARDSGNPSLFASKPAKVTIHVKDMNDSPPVFAKDTYELSVLLPVHPGMELLSVQAKDADSEVTYSIVEGNLDNAFYIHPFTGLVSILNATGLGNHHELTVRADDGLYKSTALVKLNLTQAQGSGLKFDQDVYTATVMENSTDEKTLTVLGVKGYQLNEPLFYSLLNGKERFKMIQASGVLQTKGVKFDREAQDVHEVAVEVKDNRKPPRVSQATVKVYVEDVNDNPPQFENVPYYTSVQDGMEPGDVLFQVSATDKDIGNNAAITYSFAEDYKYFWIDPYLGDISLKKPLDYHALNKYSLQVIAKDNGEPPLLAEEEVVISVRNKSNPLFQSLYYRVKVPENIPPYTSILHIQARSPEGLRLIYNIVEEDSLKLFSTDFKTGVLTVTGQLDYELQTKHSFTVRATDTALGSFSEARVEVEVEDINDNPPVFSEMIYTASVSESMPAHTPVVQIIASDKDSGRNKVVSYQILDDGSDATKFFNIDASTGQITTAQALDYEKTQQFRMKVRAADHGTPPLSSDALVIVNVTDINDNPPEFSQLQYEAKVSEMATCGHIVIKVQALDPDSGDTTRLEYVILSGNDHRHFTINSTSGIISMFNRCKKDLESSYSLRVSASDGVFKSTVPVYINTTNANKYSPSFQQNTYEAELAENAEVGTKVIELLAIDPDGGPYGTIDYTIINKLADEKFSIDNKGHITTLQKLDRENSTERVIAIKVMAKDGGGKVAFCTVKIILTDENDNPPQFKASEYTLSIQSNVSKGSPVIQVLAYDADEGANADVVYSVDSVEDVSEDIVEINAATGVVKVKESLVGLENRAFNFKVKAEDGRPPHWNSLVPVSLQIVPREVTLPRFSEPLYTFSASEDLPEGSEIGSVKAFAEDPIIYSLVKGTTTESNKDEVFTLDEQTGALKIKKAVDHETTKWYQIDVMAHCSHQETELVSLVSVNIQVQDINDNKPVFEADPYKAFVMENMPSGTTVIQVTANDQDTGSDGQVTYSLEAESGKLRGLFTIDGETGWITTLKELDCETQETYRFYVVATDHGRKVQLSSQTLVEVTVSDENDNAPQFTSDFYKGSVIENAEPGQVIVTLSTIDADISEQNRRVTCYITEGDVLGQFTVDQIEGEWTISSKKPLDREDTEKYLLKVMASDGKFQATTEVEIFVLDINDNSPECGQIFYTGRVSEDAQPGHFILKISATDPDVGSNAQITYSLHGPGAEEFRLGPHTGELTTSAPLDREQKPTYHLVAKATDGGGRSCQADITLTIEDTNDNAPRFFPSHCAVAVFDNTTTKTPIAVVSARDLDEGLNAEVVYSLSDSANGHFSIEETTGVIRLEKPLKDSQHSAFELTVCATDQGTPQPLSALGTVTVSVVDLNEYLPVFLAPEYVAMVKEDVAVGTEVLNLSALTRDNTENTEIKYEIVNGNDHGKFQLNSNTGALYINGSLDFEASHEYYLSIEGTRKGSASLSDVTMVVINITDINDHAPEFIQDPYFADIREDAAVGEIILTVSADDLDGAMNNQITYSIVEGNPLGHFAIQPKSGQISIAKHLDREEISSYSLTVRATDNGHPAQFSDVAVRVHVSDVNDNPPRFFQLNYSVVVQENAPVGTSVLELIMSDRDSPENGPPYSFQITQGNDGKAFDVTQNGLLVTSSILNRRVKEQYLLQVQVSDSGIPPLSSSAFVNIQVTEQSQYAPSALPLEIFITTNEEAFRGGVLGKIHATDRDPHDTLVYTLVAEVPQEGRFSIGAADGKIIAGNKLPHGHYLLNVTVSDGTFTATTSVNIHVWCFTQEALDRAVVLHFRHLSPEEFVGDHWRNLQRFLGNVLITRRQNIHMASLQPAATSDGVDLLLAVGEPHGSLYEPRVLANKITVSAGEMDQLVGLRMKKAIHVPCHGSDCAHRVCKETIQLDPGMMSTYSTARLSVLTPRHSLEQICSCNGTAVRFGGHSYIWYQNSQVGSWHMHFRMKTHQLHAVVFYANGTDHAMLEMVHGVLHLGYGCWGNYTGNLSSSRFVSDGEWHSVFLEVKNASVRLLVDGLGNTSLQLPGTCSTSQGRRDLLFGGLRHPLQSQRVTRGFRGCLDVLAINGREVVLLRGKGQSKEVMEEVGMKQCCSPTGACSSNPCLNNGMCSETHGGGYTCICPGLFSGERCELGDSPCESKPCLHGGTCVLSGSGYSCHCPEWYLGDRCEKLAEECQDNPCQNAGRCVSTQGSVRCICPSDYQGDYCTQPIITPAIVPTHWAVGREEIAEIAAGVLGAAILAVAFVFIRKRYRRRAKAHKPVAREDPDLLSKSEFSKSVGVGTQAVPPIELNILSDAAHNNLDRAAPEQRKASGTPEFVTFNSANGPKHRGTIVCSVAPNLPPAPPSNSDNESFVKCTWAREEMVYPAETTYWPPRYLSSDVQEYSHYEIIQGPPAVPSSHPPLPPPPPPPADPEPVTLYGGFPFPLDQSNKRAPIPPRYSNQNLEDLLPLGPVEMAASQCQNEYTAISYYPAQLVQGEGAPYPPDPGYKRVSMRLSVAQPSYADCEVGAHPPALRTQPPPPPNYEGSDMVESDYGSCEEVMF", "length": 4497, "header": "tr|A0A8V0YP25-1|A0A8V0YP25_CHICK Isoform 1 of FAT atypical cadherin 2 OS=Gallus gallus OX=9031 GN=FAT2 PE=4 SV=1 CANONICAL=A0A8V0YP25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR5/entry", "sequence": { "sequence": "MEINTKRNFLSFAVLLVHCMIRDASCEKGNTSPLHFTHFFYNATIYENSAPKTYVESYVKMGVYKTDPEWDIRYRIASGDSSGLFKTEEHVIGDFCFLRIRTRSSNTALLNREVKDSYMLIIKATENTFAYEAWAKVLIHILDRNDLKPLFSPPSYKVSIREDTPLKTVVSTLSATDADAGQNAEFYYALNTKSDLFTIHPTTGAVVTTGRLNSTHRGRHHLQVLAVDRMRKIMEGNGFGNLASLTIQVEPSAKKPPSISSVKVAPPDSAEDLLYTSLSVESGDSETGIDSVDFVDGDPGRHFAVIRSYFGSTEFMIVAIKEIDWLLHPFGFNLSLQAKDKSKPPLFSPVRVIHIPPSKYVSARFEKEVYRVQLSEFSPPGSQVAMVKITPVLPNLKYVLRPTPDSTHFKINPHTGLITTVRAMDFHEQSNFQLEVATTNSHTSATVVIDIIDCNNHAPSFSQSSYRGAFDENAPPGTSVLTVRATDEDEGDNGFVTYTIANQKSVPFVIDPYSGIISTSKSLDYELMQRWYHLRVWASDWGSPFRHETEVYVSLMLSNVNDNAPVFEKASCSGSIPRDFPVGNPVATVSAIDSDELQRIKYEIKSGNELRHFELNPISGVISLRISLRDLPSEQPLFYSLKITATDGENYALPTSVNITVVSQGLPVKMQCEETGVLKQLTETIIHSIESQSEGQGQDDETTLNLHLINHNAPKFDDSFPRSIDIIENVPINSTIADLSAVDPDTGFNGKLVYVISDGNVDSCFTIDLELGLLQILSPLDHERTSFYILNITVYDLGTPQKSSWKLLAVNVLDTNDNTPRFPQGAYWVAIPENVVTGTTIAQLKAEDADTDDNGRVKYSLLTPTDKFAINSVTGEVTVIGALDRELWPYYALKIKARDQPKTGYQLFSVTDLIVTLEDVNDNDPHCLPALNNVKVPEDLPVGTILLFLEAFDPDAGSGGEVRYSLVNDEEMMFHIDKLTGALRLEKELDYEKKDSYNLTVQVRDSGKPVSRSSLCHLEVNVLDVNENLYPPRFASFVFKGWVQENSPEGTSVMMVTAKDIDKGKDGEVQYFLREGTGLSVFSIEKDTGTIRTIGPLDREGTSHYWLTVLALDLGTVPLSSATEIYIEVTDTNDNPPQMSRPVYYASVMENSPPNTSVLQLDALDPDSSSEGKLTFHILTGNPQGLFAINLVTGLISTTSRQLDREYKAEHILEVAVSDNGDPALKSTSRVVIQVLDANDNPPSFPHKLFMVQLPEREASETPLPVYRLIASDRDQGQNSQVTYTIEEEEEGIFTINPTTGMVLSRKAFPASEYNILTVKATDGGSPPLSSHVRLHISWVVRPGPSSEPLAFDEPHFNFAVMETDPVNHMVGVISIEMGPSQVWFNITGGDDDMDFDIEKSTGSMVIARALDARKKSSYNLTVEVTDGSTTIKTQAFIHVIDINQHRPQFLESHYEMRIPEDTPSGREILQVSATDKDKGKGLIYTIHGSMDPRSTRLFQLDPSSGVLTTAEGFSSQPMPQHTLTVMVRDQEVPIKRNFVRVIIHVENCNLHPPQFSSIHYEAETLDSAAVGTEIVQVRALDQDQGANAEIHYSLQAGNGEGFFSIDPHSGIITVAQKLDPSKQERFTLIVKAEDQGFPQLKDSATVHIRIRPSDQTPPKFPEAEYITEISESAAVGSPLIQVSTSSSSPVSYEIKDGNGDGVFSMNYQSGLISTQKNLDFEQVSFYQLKVRGTNMAGAFMDTMVLIYVIDENDNVPIFVKPAFIGWIMENAPPQSMVLDESNSPLVTHATDADQDSNALLVYEILEPEALKYFTVDPSTGTLTSRADIDYELTPVFHFSVHARDSGNPSLFASKPAKVTIHVKDMNDSPPVFAKDTYELSVLLPVHPGMELLSVQAKDADSEVTYSIVEGNLDNAFYIHPFTGLVSILNATGLGNHHELTVRADDGLYKSTALVKLNLTQAQGSGLKFDQDVYTATVMENSTDEKTLTVLGVKGYQLNEPLFYSLLNGKERFKMIQASGVLQTKGVKFDREAQDVHEVAVEVKDNRKPPRVSQATVKVYVEDVNDNPPQFENVPYYTSVQDGMEPGDVLFQVSATDKDIGNNAAITYSFAEDYKYFWIDPYLGDISLKKPLDYHALNKYSLQVIAKDNGEPPLLAEEEVVISVRNKSNPLFQSLYYRVKVPENIPPYTSILHIQARSPEGLRLIYNIVEEDSLKLFSTDFKTGVLTVTGQLDYELQTKHSFTVRATDTALGSFSEARVEVEVEDINDNPPVFSEMIYTASVSESMPAHTPVVQIIASDKDSGRNKVVSYQILDDGSDATKFFNIDASTGQITTAQALDYEKTQQFRMKVRAADHGTPPLSSDALVIVNVTDINDNPPEFSQLQYEAKVSEMATCGHIVIKVQALDPDSGDTTRLEYVILSGNDHRHFTINSTSGIISMFNRCKKDLESSYSLRVSASDGVFKSTVPVYINTTNANKYSPSFQQNTYEAELAENAEVGTKVIELLAIDPDGGPYGTIDYTIINKLADEKFSIDNKGHITTLQKLDRENSTERVIAIKVMAKDGGGKVAFCTVKIILTDENDNPPQFKASEYTLSIQSNVSKGSPVIQVLAYDADEGANADVVYSVDSVEDVSEDIVEINAATGVVKVKESLVGLENRAFNFKVKAEDGRPPHWNSLVPVSLQIVPREVTLPRFSEPLYTFSASEDLPEGSEIGSVKAFAEDPIIYSLVKGTTTESNKDEVFTLDEQTGALKIKKAVDHETTKWYQIDVMAHCSHQETELVSLVSVNIQVQDINDNKPVFEADPYKAFVMENMPSGTTVIQVTANDQDTGSDGQVTYSLEAESGKLRGLFTIDGETGWITTLKELDCETQETYRFYVVATDHGRKVQLSSQTLVEVTVSDENDNAPQFTSDFYKGSVIENAEPGQVIVTLSTIDADISEQNRRVTCYITEGDVLGQFTVDQIEGEWTISSKKPLDREDTEKYLLKVMASDGKFQATTEVEIFVLDINDNSPECGQIFYTGRVSEDAQPGHFILKISATDPDVGSNAQITYSLHGPGAEEFRLGPHTGELTTSAPLDREQKPTYHLVAKATDGGGRSCQADITLTIEDTNDNAPRFFPSHCAVAVFDNTTTKTPIAVVSARDLDEGLNAEVVYSLSDSANGHFSIEETTGVIRLEKPLKDSQHSAFELTVCATDQGTPQPLSALGTVTVSVVDLNEYLPVFLAPEYVAMVKEDVAVGTEVLNLSALTRDNTENTEIKYEIVNGNDHGKFQLNSNTGALYINGSLDFEASHEYYLSIEGTRKGSASLSDVTMVVINITDINDHAPEFIQDPYFADIREDAAVGEIILTVSADDLDGAMNNQITYSIVEGNPLGHFAIQPKSGQISIAKHLDREEISSYSLTVRATDNGHPAQFSDVAVRVHVSDVNDNPPRFFQLNYSVVVQENAPVGTSVLELIMSDRDSPENGPPYSFQITQGNDGKAFDVTQNGLLVTSSILNRRVKEQYLLQVQVSDSGIPPLSSSAFVNIQVTEQSQYAPSALPLEIFITTNEEAFRGGVLGKIHATDRDPHDTLVYTLVAEVPQEGRFSIGAADGKIIAGNKLPHGHYLLNVTVSDGTFTATTSVNIHVWCFTQEALDRAVVLHFRHLSPEEFVGDHWRNLQRFLGNVLITRRQNIHMASLQPAATSDGVDLLLAVGEPHGSLYEPRVLANKITVSAGEMDQLVGLRMKKAIHVPCHGSDCAHRVCKETIQLDPGMMSTYSTARLSVLTPRHSLEQICSCNGTAVRFGGHSYIWYQNSQVGSWHMHFRMKTHQLHAVVFYANGTDHAMLEMVHGVLHLGYGCWGNYTGNLSSSRFVSDGEWHSVFLEVKNASVRLLVDGLGNTSLQLPGTCSTSQGRRDLLFGGLRHPLQSQRVTRGFRGCLDVLAINGREVVLLRGKGQSKEVMEEVGMKQCCSPTGACSSNPCLNNGMCSETHGGGARSWLRSARTTRAKTPGAA", "length": 3990, "header": "tr|A0A8V0YHR5-1|A0A8V0YP25_CHICK Computationally mapped isoform of FAT atypical cadherin 2 OS=Gallus gallus OX=9031 GN=FAT2 PE=4 SV=1 CANONICAL=A0A8V0YP25-1" }, "locus": { "chromosome": "13", "start_pos": 12597375, "end_pos": 12562549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034895.1", "url": "https://www.ensembl.org/id/ENSGALT00010034895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020422.1", "url": "https://www.ensembl.org/id/ENSGALP00010020422.1" } ] } }, { "isoform_ac": "A0A8V0YP25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25/entry", "sequence": { "sequence": "MLQKPSKIIKSNDPPNTGPLPLFFPKASHPPPYKTCFLCSPFRFLCDHQIPHPDLDCPSTVYLSNLPSPSAPSVGSLQGIGVLRVGFDGYLFQDLRRHHTMEINTKRNFLSFAVLLVHCMIRDASCEKGNTSPLHFTHFFYNATIYENSAPKTYVESYVKMGVYKTDPEWDIRYRIASGDSSGLFKTEEHVIGDFCFLRIRTRSSNTALLNREVKDSYMLIIKATENTFAYEAWAKVLIHILDRNDLKPLFSPPSYKVSIREDTPLKTVVSTLSATDADAGQNAEFYYALNTKSDLFTIHPTTGAVVTTGRLNSTHRGRHHLQVLAVDRMRKIMEGNGFGNLASLTIQVEPSAKKPPSISSVKVAPPDSAEDLLYTSLSVESGDSETGIDSVDFVDGDPGRHFAVIRSYFGSTEFMIVAIKEIDWLLHPFGFNLSLQAKDKSKPPLFSPVRVIHIPPSKYVSARFEKEVYRVQLSEFSPPGSQVAMVKITPVLPNLKYVLRPTPDSTHFKINPHTGLITTVRAMDFHEQSNFQLEVATTNSHTSATVVIDIIDCNNHAPSFSQSSYRGAFDENAPPGTSVLTVRATDEDEGDNGFVTYTIANQKSVPFVIDPYSGIISTSKSLDYELMQRWYHLRVWASDWGSPFRHETEVYVSLMLSNVNDNAPVFEKASCSGSIPRDFPVGNPVATVSAIDSDELQRIKYEIKSGNELRHFELNPISGVISLRISLRDLPSEQPLFYSLKITATDGENYALPTSVNITVVSQGLPVKMQCEETGVLKQLTETIIHSIESQSEGQGQDDETTLNLHLINHNAPKFDDSFPRSIDIIENVPINSTIADLSAVDPDTGFNGKLVYVISDGNVDSCFTIDLELGLLQILSPLDHERTSFYILNITVYDLGTPQKSSWKLLAVNVLDTNDNTPRFPQGAYWVAIPENVVTGTTIAQLKAEDADTDDNGRVKYSLLTPTDKFAINSVTGEVTVIGALDRELWPYYALKIKARDQPKTGYQLFSVTDLIVTLEDVNDNDPHCLPALNNVKVPEDLPVGTILLFLEAFDPDAGSGGEVRYSLVNDEEMMFHIDKLTGALRLEKELDYEKKDSYNLTVQVRDSGKPVSRSSLCHLEVNVLDVNENLYPPRFASFVFKGWVQENSPEGTSVMMVTAKDIDKGKDGEVQYFLREGTGLSVFSIEKDTGTIRTIGPLDREGTSHYWLTVLALDLGTVPLSSATEIYIEVTDTNDNPPQMSRPVYYASVMENSPPNTSVLQLDALDPDSSSEGKLTFHILTGNPQGLFAINLVTGLISTTSRQLDREYKAEHILEVAVSDNGDPALKSTSRVVIQVLDANDNPPSFPHKLFMVQLPEREASETPLPVYRLIASDRDQGQNSQVTYTIEEEEEGIFTINPTTGMVLSRKAFPASEYNILTVKATDGGSPPLSSHVRLHISWVVRPGPSSEPLAFDEPHFNFAVMETDPVNHMVGVISIEMGPSQVWFNITGGDDDMDFDIEKSTGSMVIARALDARKKSSYNLTVEVTDGSTTIKTQAFIHVIDINQHRPQFLESHYEMRIPEDTPSGREILQVSATDKDKGKGLIYTIHGSMDPRSTRLFQLDPSSGVLTTAEGFSSQPMPQHTLTVMVRDQEVPIKRNFVRVIIHVENCNLHPPQFSSIHYEAETLDSAAVGTEIVQVRALDQDQGANAEIHYSLQAGNGEGFFSIDPHSGIITVAQKLDPSKQERFTLIVKAEDQGFPQLKDSATVHIRIRPSDQTPPKFPEAEYITEISESAAVGSPLIQVSTSSSSPVSYEIKDGNGDGVFSMNYQSGLISTQKNLDFEQVSFYQLKVRGTNMAGAFMDTMVLIYVIDENDNVPIFVKPAFIGWIMENAPPQSMVLDESNSPLVTHATDADQDSNALLVYEILEPEALKYFTVDPSTGTLTSRADIDYELTPVFHFSVHARDSGNPSLFASKPAKVTIHVKDMNDSPPVFAKDTYELSVLLPVHPGMELLSVQAKDADSEVTYSIVEGNLDNAFYIHPFTGLVSILNATGLGNHHELTVRADDGLYKSTALVKLNLTQAQGSGLKFDQDVYTATVMENSTDEKTLTVLGVKGYQLNEPLFYSLLNGKERFKMIQASGVLQTKGVKFDREAQDVHEVAVEVKDNRKPPRVSQATVKVYVEDVNDNPPQFENVPYYTSVQDGMEPGDVLFQVSATDKDIGNNAAITYSFAEDYKYFWIDPYLGDISLKKPLDYHALNKYSLQVIAKDNGEPPLLAEEEVVISVRNKSNPLFQSLYYRVKVPENIPPYTSILHIQARSPEGLRLIYNIVEEDSLKLFSTDFKTGVLTVTGQLDYELQTKHSFTVRATDTALGSFSEARVEVEVEDINDNPPVFSEMIYTASVSESMPAHTPVVQIIASDKDSGRNKVVSYQILDDGSDATKFFNIDASTGQITTAQALDYEKTQQFRMKVRAADHGTPPLSSDALVIVNVTDINDNPPEFSQLQYEAKVSEMATCGHIVIKVQALDPDSGDTTRLEYVILSGNDHRHFTINSTSGIISMFNRCKKDLESSYSLRVSASDGVFKSTVPVYINTTNANKYSPSFQQNTYEAELAENAEVGTKVIELLAIDPDGGPYGTIDYTIINKLADEKFSIDNKGHITTLQKLDRENSTERVIAIKVMAKDGGGKVAFCTVKIILTDENDNPPQFKASEYTLSIQSNVSKGSPVIQVLAYDADEGANADVVYSVDSVEDVSEDIVEINAATGVVKVKESLVGLENRAFNFKVKAEDGRPPHWNSLVPVSLQIVPREVTLPRFSEPLYTFSASEDLPEGSEIGSVKAFAEDPIIYSLVKGTTTESNKDEVFTLDEQTGALKIKKAVDHETTKWYQIDVMAHCSHQETELVSLVSVNIQVQDINDNKPVFEADPYKAFVMENMPSGTTVIQVTANDQDTGSDGQVTYSLEAESGKLRGLFTIDGETGWITTLKELDCETQETYRFYVVATDHGRKVQLSSQTLVEVTVSDENDNAPQFTSDFYKGSVIENAEPGQVIVTLSTIDADISEQNRRVTCYITEGDVLGQFTVDQIEGEWTISSKKPLDREDTEKYLLKVMASDGKFQATTEVEIFVLDINDNSPECGQIFYTGRVSEDAQPGHFILKISATDPDVGSNAQITYSLHGPGAEEFRLGPHTGELTTSAPLDREQKPTYHLVAKATDGGGRSCQADITLTIEDTNDNAPRFFPSHCAVAVFDNTTTKTPIAVVSARDLDEGLNAEVVYSLSDSANGHFSIEETTGVIRLEKPLKDSQHSAFELTVCATDQGTPQPLSALGTVTVSVVDLNEYLPVFLAPEYVAMVKEDVAVGTEVLNLSALTRDNTENTEIKYEIVNGNDHGKFQLNSNTGALYINGSLDFEASHEYYLSIEGTRKGSASLSDVTMVVINITDINDHAPEFIQDPYFADIREDAAVGEIILTVSADDLDGAMNNQITYSIVEGNPLGHFAIQPKSGQISIAKHLDREEISSYSLTVRATDNGHPAQFSDVAVRVHVSDVNDNPPRFFQLNYSVVVQENAPVGTSVLELIMSDRDSPENGPPYSFQITQGNDGKAFDVTQNGLLVTSSILNRRVKEQYLLQVQVSDSGIPPLSSSAFVNIQVTEQSQYAPSALPLEIFITTNEEAFRGGVLGKIHATDRDPHDTLVYTLVAEVPQEGRFSIGAADGKIIAGNKLPHGHYLLNVTVSDGTFTATTSVNIHVWCFTQEALDRAVVLHFRHLSPEEFVGDHWRNLQRFLGNVLITRRQNIHMASLQPAATSDGVDLLLAVGEPHGSLYEPRVLANKITVSAGEMDQLVGLRMKKAIHVPCHGSDCAHRVCKETIQLDPGMMSTYSTARLSVLTPRHSLEQICSCNGTAVRFGGHSYIWYQNSQVGSWHMHFRMKTHQLHAVVFYANGTDHAMLEMVHGVLHLGYGCWGNYTGNLSSSRFVSDGEWHSVFLEVKNASVRLLVDGLGNTSLQLPGTCSTSQGRRDLLFGGLRHPLQSQRVTRGFRGCLDVLAINGREVVLLRGKGQSKEVMEEVGMKQCCSPTGACSSNPCLNNGMCSETHGGGYTCICPGLFSGERCELGDSPCESKPCLHGGTCVLSGSGYSCHCPEWYLGDRCEKLAEECQDNPCQNAGRCVSTQGSVRCICPSDYQGDYCTQPIITPAIVPTHWAVGREEIAEIAAGVLGAAILAVAFVFIRKRYRRRAKAHKPVAREDPDLLSKSEFSKSVGVGTQAVPPIELNILSDAAHNNLDRAAPEQRKASGTPEFVTFNSANGPKHRGTIVCSVAPNLPPAPPSNSDNESFVKCTWAREEMVYPAETTYWPPRYLSSDVQEYSHYEIIQGPPAVPSSHPPLPPPPPPPADPEPVTLYGGFPFPLDQSNKRAPIPPRYSNQNLEDLLPLGPVEMAASQCQNEYTAISYYPAQLVQGEGAPYPPDPGYKRVSMRLSVAQPSYADCEVGAHPPALRTQPPPPPNYEGSDMVESDYGSCEEVMF", "length": 4497, "header": "tr|A0A8V0YP25-1|A0A8V0YP25_CHICK Isoform 1 of FAT atypical cadherin 2 OS=Gallus gallus OX=9031 GN=FAT2 PE=4 SV=1 CANONICAL=A0A8V0YP25-1" }, "locus": { "chromosome": "13", "start_pos": 12599299, "end_pos": 12558627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034882.1", "url": "https://www.ensembl.org/id/ENSGALT00010034882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020421.1", "url": "https://www.ensembl.org/id/ENSGALP00010020421.1" } ] } }, { "isoform_ac": "A0A8V0YP58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP58/entry", "sequence": { "sequence": "MEINTKRNFLSFAVLLVHCMIRDASCEKGNTSPLHFTHFFYNATIYENSAPKTYVESYVKMGVYKTDPEWDIRYRIASGDSSGLFKTEEHVIGDFCFLRIRTRSSNTALLNREVKDSYMLIIKATENTFAYEAWAKVLIHILDRNDLKPLFSPPSYKVSIREDTPLKTVVSTLSATDADAGQNAEFYYALNTKSDLFTIHPTTGAVVTTGRLNSTHRGRHHLQVLAVDRMRKIMEGNGFGNLASLTIQVEPSAKKPPSISSVKVAPPDSAEDLLYTSLSVESGDSETGIDSVDFVDGDPGRHFAVIRSYFGSTEFMIVAIKEIDWLLHPFGFNLSLQAKDKSKPPLFSPVRVIHIPPSKYVSARFEKEVYRVQLSEFSPPGSQVAMVKITPVLPNLKYVLRPTPDSTHFKINPHTGLITTVRAMDFHEQSNFQLEVATTNSHTSATVVIDIIDCNNHAPSFSQSSYRGAFDENAPPGTSVLTVRATDEDEGDNGFVTYTIANQKSVPFVIDPYSGIISTSKSLDYELMQRWYHLRVWASDWGSPFRHETEVYVSLMLSNVNDNAPVFEKASCSGSIPRDFPVGNPVATVSAIDSDELQRIKYEIKSGNELRHFELNPISGVISLRISLRDLPSEQPLFYSLKITATDGENYALPTSVNITVVSQGLPVKMQCEETGVLKQLTETIIHSIESQSEGQGQDDETTLNLHLINHNAPKFDDSFPRSIDIIENVPINSTIADLSAVDPDTGFNGKLVYVISDGNVDSCFTIDLELGLLQILSPLDHERTSFYILNITVYDLGTPQKSSWKLLAVNVLDTNDNTPRFPQGAYWVAIPENVVTGTTIAQLKAEDADTDDNGRVKYSLLTPTDKFAINSVTGEVTVIGALDRELWPYYALKIKARDQPKTGYQLFSVTDLIVTLEDVNDNDPHCLPALNNVKVPEDLPVGTILLFLEAFDPDAGSGGEVRYSLVNDEEMMFHIDKLTGALRLEKELDYEKKDSYNLTVQVRDSGKPVSRSSLCHLEVNVLDVNENLYPPRFASFVFKGWVQENSPEGTSVMMVTAKDIDKGKDGEVQYFLREGTGLSVFSIEKDTGTIRTIGPLDREGTSHYWLTVLALDLGTVPLSSATEIYIEVTDTNDNPPQMSRPVYYASVMENSPPNTSVLQLDALDPDSSSEGKLTFHILTGNPQGLFAINLVTGLISTTSRQLDREYKAEHILEVAVSDNGDPALKSTSRVVIQVLDANDNPPSFPHKLFMVQLPEREASETPLPVYRLIASDRDQGQNSQVTYTIEEEEEGIFTINPTTGMVLSRKAFPASEYNILTVKATDGGSPPLSSHVRLHISWVVRPGPSSEPLAFDEPHFNFAVMETDPVNHMVGVISIEMGPSQVWFNITGGDDDMDFDIEKSTGSMVIARALDARKKSSYNLTVEVTDGSTTIKTQAFIHVIDINQHRPQFLESHYEMRIPEDTPSGREILQVSATDKDKGKGLIYTIHGSMDPRSTRLFQLDPSSGVLTTAEGFSSQPMPQHTLTVMVRDQEVPIKRNFVRVIIHVENCNLHPPQFSSIHYEAETLDSAAVGTEIVQVRALDQDQGANAEIHYSLQAGNGEGFFSIDPHSGIITVAQKLDPSKQERFTLIVKAEDQGFPQLKDSATVHIRIRPSDQTPPKFPEAEYITEISESAAVGSPLIQVSTSSSSPVSYEIKDGNGDGVFSMNYQSGLISTQKNLDFEQVSFYQLKVRGTNMAGAFMDTMVLIYVIDENDNVPIFVKPAFIGWIMENAPPQSMVLDESNSPLVTHATDADQDSNALLVYEILEPEALKYFTVDPSTGTLTSRADIDYELTPVFHFSVHARDSGNPSLFASKPAKVTIHVKDMNDSPPVFAKDTYELSVLLPVHPGMELLSVQAKDADSEVTYSIVEGNLDNAFYIHPFTGLVSILNATGLGNHHELTVRADDGLYKSTALVKLNLTQAQGSGLKFDQDVYTATVMENSTDEKTLTVLGVKGYQLNEPLFYSLLNGKERFKMIQASGVLQTKGVKFDREAQDVHEVAVEVKDNRKPPRVSQATVKVYVEDVNDNPPQFENVPYYTSVQDGMEPGDVLFQVSATDKDIGNNAAITYSFAEDYKYFWIDPYLGDISLKKPLDYHALNKYSLQVIAKDNGEPPLLAEEEVVISVRNKSNPLFQSLYYRVKVPENIPPYTSILHIQARSPEGLRLIYNIVEEDSLKLFSTDFKTGVLTVTGQLDYELQTKHSFTVRATDTALGSFSEARVEVEVEDINDNPPVFSEMIYTASVSESMPAHTPVVQIIASDKDSGRNKVVSYQILDDGSDATKFFNIDASTGQITTAQALDYEKTQQFRMKVRAADHGTPPLSSDALVIVNVTDINDNPPEFSQLQYEAKVSEMATCGHIVIKVQALDPDSGDTTRLEYVILSGNDHRHFTINSTSGIISMFNRCKKDLESSYSLRVSASDGVFKSTVPVYINTTNANKYSPSFQQNTYEAELAENAEVGTKVIELLAIDPDGGPYGTIDYTIINKLADEKFSIDNKGHITTLQKLDRENSTERVIAIKVMAKDGGGKVAFCTVKIILTDENDNPPQFKASEYTLSIQSNVSKGSPVIQVLAYDADEGANADVVYSVDSVEDVSEDIVEINAATGVVKVKESLVGLENRAFNFKVKAEDGRPPHWNSLVPVSLQIVPREVTLPRFSEPLYTFSASEDLPEGSEIGSVKAFAEDPIIYSLVKGTTTESNKDEVFTLDEQTGALKIKKAVDHETTKWYQIDVMAHCSHQETELVSLVSVNIQVQDINDNKPVFEADPYKAFVMENMPSGTTVIQVTANDQDTGSDGQVTYSLEAESGKLRGLFTIDGETGWITTLKELDCETQETYRFYVVATDHGRKVQLSSQTLVEVTVSDENDNAPQFTSDFYKGSVIENAEPGQVIVTLSTIDADISEQNRRVTCYITEGDVLGQFTVDQIEGEWTISSKKPLDREDTEKYLLKVMASDGKFQATTEVEIFVLDINDNSPECGQIFYTGRVSEDAQPGHFILKISATDPDVGSNAQITYSLHGPGAEEFRLGPHTGELTTSAPLDREQKPTYHLVAKATDGGGRSCQADITLTIEDTNDNAPRFFPSHCAVAVFDNTTTKTPIAVVSARDLDEGLNAEVVYSLSDSANGHFSIEETTGVIRLEKPLKDSQHSAFELTVCATDQGTPQPLSALGTVTVSVVDLNEYLPVFLAPEYVAMVKEDVAVGTEVLNLSALTRDNTENTEIKYEIVNGNDHGKFQLNSNTGALYINGSLDFEASHEYYLSIEGTRKGSASLSDVTMVVINITDINDHAPEFIQDPYFADIREDAAVGEIILTVSADDLDGAMNNQITYSIVEGNPLGHFAIQPKSGQISIAKHLDREEISSYSLTVRATDNGHPAQFSDVAVRVHVSDVNDNPPRFFQLNYSVVVQENAPVGTSVLELIMSDRDSPENGPPYSFQITQGNDGKAFDVTQNGLLVTSSILNRRVKEQYLLQVQVSDSGIPPLSSSAFVNIQVTEQSQYAPSALPLEIFITTNEEAFRGGVLGKIHATDRDPHDTLVYTLVAEVPQEGRFSIGAADGKIIAGNKLPHGHYLLNVTVSDGTFTATTSVNIHVWCFTQEALDRAVVLHFRHLSPEEFVGDHWRNLQRFLGNVLITRRQNIHMASLQPAATSDGVDLLLAVGEPHGSLYEPRVLANKITVSAGEMDQLVGLRMKKAIHVPCHGSDCAHRVCKETIQLDPGMMSTYSTARLSVLTPRHSLEQICSCNGTAVRFGGHSYIWYQNSQVGSWHMHFRMKTHQLHAVVFYANGTDHAMLEMVHGVLHLGYGCWGNYTGNLSSSRFVSDGEWHSVFLEVKNASVRLLVDGLGNTSLQLPGTCSTSQGRRDLLFGGLRHPLQSQRVTRGFRGCLDVLAINGREVVLLRGKGQSKEVMEEVGMKQCCSPTGACSSNPCLNNGMCSETHGGGYTCICPGLFSGERCELGDSPCESKPCLHGGTCVLSGSGYSCHCPEWYLGDRCEKLAEECQDNPCQNAGRCVSTQGSVRCICPSDYQGDYCTQPIITPAIVPTHWAVGREEIAEIAAGVLGAAILAVAFVFIRKRYRRRAKAHKPVAREDPDLLSKSEFSKSVGVGTQAVPPIELNILSDAAHNNLDRAAPEQRKASGTPEFVTFNSANGPKHRGTIVCSVAPNLPPAPPSNSDNESFVKCTWAREEMVYPAETTYWPPRYLSSDVQEYSHYEIIQGPPAVPSSHPPLPPPPPPPADPEPVTLYGGFPFPLDQSNKRAPIPPRYSNQNLEDLLPLGPVEMAASQCQNEYTAISYYPAQLVQGEGAPYPPDPGYKRVSMRLSVAQPSYADCEVGAHPPALRTQPPPPPNYEGSDMVESDYGSCEEVMF", "length": 4397, "header": "tr|A0A8V0YP58-1|A0A8V0YP58_CHICK Computationally mapped isoform of FAT atypical cadherin 2 OS=Gallus gallus OX=9031 GN=FAT2 PE=4 SV=1 CANONICAL=A0A8V0YP25-1" }, "locus": { "chromosome": "13", "start_pos": 12599299, "end_pos": 12562549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034905.1", "url": "https://www.ensembl.org/id/ENSGALT00010034905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020424.1", "url": "https://www.ensembl.org/id/ENSGALP00010020424.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4008, "start_aa": "Thr", "end_pos": 4008, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4008", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416266", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FB42-1", "protein_name": "Protocadherin Fat 2", "gene_name": "fat2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFTDTAIILTVIAVLGTLTRCHGSLVKDSSLLRFTHHLYNASIYENSAPKTYVESSVRMGILLTDPFWNIKYKIVSGDDDGLFQTEKEDVGDFSFLRIITRSSNSAVLNREVRDIYTLTVEATESTFDNRARTKVLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTRSHPFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQKFGNVATVVVKIQKVEKNFTLISPTTAESLLTIDDKISVNIKMEPKEKENTASLSIVKGDPLNCFQIIPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIKTVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSVGLSLKNTTFSIQENPDSYKFKISAKTGVIVTSQSLDFENRNHYEFDVTANDGEAVTRVIVDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAIANTGPVPFSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLDELQQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNTVTVSITDNGEGAITHCEETGITRQLTEKLIESFRPSLNIKEEESISDVHIINQHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSISSGNEDGCFTIDVNAGDLKVICALDREQKEFYILNITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDLDNNGAFKYSLFTFTDLFQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSESGTFFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQILDSQRIYFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNNEGRFDIHPDTGVVTARGQFVRGNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPVTDMVGIIRTEIPKNLLLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSVSARCPSSVLYRINEGDPNGTFHININSGLLSVKNALDFEQHSSYHLQISATNTAGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMGTISLKSLIDFEATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALTWPVFQDMKVIQVTAHDADSAVTYMILENSNKNAFKIDQSTGVISVNDSSELQSHNELKITAFDGLYKDTTVVKLNITNATKSSLKFEDRAHVATVLENSTSVKILVVLRATGTYLNEPLQFTVLNPHGKFAVIPSSGVLHTTGVPFDREEQDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDDFGLFRIDLYLGDVSLQRPLDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQNRSHPIFQSMYYPLKLPENITPFTTILHVQARNPEGYRLIYNLEEDNASRLFNIDFKTGVLSVTDFLDFESETKHILTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQVSAVDRDADKNAEATYQLIDKESHFFEIDPLSGVLVTTQVLDYESTQQFTLKVKATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPDSKDDLQYKILSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGVFQKTAPVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINKLADEKFAINEDGQIVTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDLPIGYEIGTVKADADMPLIYSLVNGNTLDSNKELSFAIDKDGGTVVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYTLEPESDDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATDGRFQTSANVEVHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGPNADKFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGGRSCQADVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGADSGFFSLDEISGVLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSVQIAESSQVGSEVISVSALTKDATENEPVRYSIISGNEDGRFMINPVTGLLSVKAALDFERCREYYLSVEGARGKPLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPEDISPGEMALQVRAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHYSLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTDRDTPQNGPPFSFHIVSGNEDRSFHIDQGGLLSVSSQLRRRGKPQHLLKIQVTDSGHPPLSSICVVKINITEQSRYPPTVNPLEIFITTAGGPILKSVISKLHATDQDPQDVLSYKLVSEGQDKGLFSVDTVDGKIVVEKNLDPGLYHLNVSVTDGKFSIWAGVKVHVWAATQQNLDQGFTLQLAGISAEEFVSDHWRGLQRSLAQELNIPRQELHIASLQQQPNSVNTEVLLVRRAQDGSVKSVPVQRLTGVLSTVEDTLGLNVLRLKHDGCVGAGCPPRGCKNTVVMRQGRMSNYATARMNFITPQHSWESMCTCNESAVRFDGKGYLKYLYHMEEAKENFHLSLRLKTSAADGTVMATNASDWGTLELVDKELWLRYRCGNMLSAGLQVANYPVADGRWHHVSLDVNDTTLRLTIDSSHTNSVVLPQPCRLSHPGGALVLASSNPNTDAERLGFTGCLESVHFNGEALRRQEGMTGAGAQAGKLFGIYQCCSDVEICASNPCENGGICAENSTGGFHCSCPSMYYGPHCQFIHLPDDPCSSKPCVDGLCMPNNQGYICNCSTQIAGNRCPTSCAPNSCQDGFTCSMVANSVHCERTTYRSTYIPYVEIAEICAGVVGLVLLVIAFVCFRKHYVSKKKHKSGCVQDSNGYFPTLPKTMTKEAEISSPMDGMLIGSVGDLESSPFRSLKLREQRELGPQVGPRPQRPQGPVICSVAPNLPPPPSTSSDNDSIMKNNWEHDYEVYPADPDYYGRPAVQEFPQFDIVESTYSNTSTESRRNSRFGGFPFPLDRADRRAPLPPCYSNQNLDDFLGPDGLPLPRSQCPNEYTAISYYPTQHARSLDNVSSGYKRLSVRLSVAQPSYADSTRPGSTRRTSRSYAGSDRVESDYGSCEEVMF", "length": 4342 }, "evidence": [ { "id": "A0A8V0YP25", "url": "https://omabrowser.org/oma/group/A0A8V0YP25/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MPF3-1", "protein_name": "Protocadherin Fat 2", "gene_name": "FAT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIIASLGFAILLFHCTTCENPLISSAWHFTHPLYNATIYENSAPKTYVESSEKMGIYLINPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEKTLELEALARVVVRILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVSATDADLGQNAEFYYAFNTRSEMFAIHPTSGVVTLAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGNLAALVIHVEPALRKPPAISSVVLDALDRSEDATYATVMVDANSSGADVDSLEIVGGDPGKNFKAIKSYARSSEFSVVSVKDINWMDHPHGFNLSLQARAGSRPSVYSQIRGFHLPPSKLTSLKFEKATYRVQLSEFSPTGSRVVMVKVTPAFPNLKYVLKPSSESAAFKLNARTGLITTTKLMDFHDQAQYQLRIRTSPGLASTTVVIDIMDCNNHAPVFNRSSYDGTFDENIPPGTSVLTVTATDQDHGENGYITYSITRPNAVPFSIDPYLGIISTSKPMDYELMNRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNKPMFEEVNCTGSIHEDWPVGKSVMTVSAIDVDELLNLKYEFVSGNELEYFDLNHFSGVISLKRSFRNRTTGQPINYSLKITASDGKNYASPMTLNVTVVKDPHFEVPVKCEKTGVLTHFTKTILHSIGLQNQESNDEDFTSLSAYQINHHTPQFEDHFPQSIDILESAPLNTPLAHLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATSFYVLNVTVYDLGTPQKSSWKLLTVNVEDWNDNAPRFPPGGYQVTISEDTEVGTTVAELKAKDVDSEDNGRVRYVLLSPTEKFSLHPLTGEMVVTGHLDRESEPRYILKVEARDQPRKGHQLFSVTDLIITLEDVNDNSPQCITEHRRLKVPEDLPPATILTFLDASDPDLGPAGEVQYVLLDDAHGTFHVNPMTGALSLEKELDFERRAGYNLSLWASDSGKPLARRTLCHVEVTVLDVNENLHPPRFASFVHQGQVQENSPSGTSVMVVAAHDDDTGLDGELQYFLRGGTGLAAFSINQDTGMIQTLAPLDREFASCYWLTVLAVDRGSIPLSSVTEVYIEVLDVNDNPPQMSRPVFYPTVREDAPLHTSVLQLDAWDLDSSSKGKLTFNITSGNHMGFFVLHPLTGLLATARQLDRENKDEHILEVTVLDNGEPSLRSTSRVVVRIADVNDNPPVFSHKLFNVRLPERLNPGTSGPVYRLVASDLDEGLNGRVTYSIEESDEAGFSIDPVTGVVSASSTFTAGEYNILTVKATDGGQPPLSASVRLHIEWIPKPRPSSIPLAFDESHYSFTVMETDPVNHMVGVISVEGRPGLFWFSISGGDKDMDFDIEKTTGSIVIARPLDTRRRSSYNLTVEVTDGFQTIATQVYIVMIANVNHHRPQFLEAHYEVRVPQDTMPGVELLRVQATDQDKGKGLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEMPIKRNFVWVSIHVEDGNLHPPRFTQLHYETRVSDTTVPGAELLQVRAMDGDRGANAEVHYSFLKGNSEGFFNINALLGIITLAQKLDQANHARYTLTVKAEDQGSPQGHDLATVIIHVYPSDSSAPIFSNSEYFVEIPESIPVGSPILLISATSFSEVTYELREGNKNGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGTFTDVMVLVYIIDENDNAPVFSKSTFVGQISEAAPLNSMIMDENNNPLVIRASDSDKEANSLLVYKILEPETLKFLKIDPSMGTLTTVLEMDYESMPSFRFDIYVHDQGSPILFAPRAAQVIINVRNVNDCPPRFLDQIYEVAIMKPIHRGMELLMVQASDDDSEVTYSIKTGNADEAIAMHPITGRISVLDPTLLGLSRELIIRASDGLYQDTALVKISWTQASNTTLQFDRDVYRATVKENLLERKALVILGAQGNHLNDTLSYFLLNGTDMFHMIKSAGVLQTRGVGFDREQQDTHEVAVELRDNRTPQRVAQALVRVSVEDVNDNSPEFKHLPYHTIIQDGTEPGDVLFQVSATDQDLGVNGAVTYAFAEDYTYFRIDPYLGDISLRKPFDYQALNKYRLKVIAQDGGTPSLQAEEEVLVIVRNKSNPLFQTPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGQNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDRGDPPLTGETLVVVNVSDINDNPPEFRQPHYEANVSELATCGHLVLKVQALDPDSRDTSRLEYLILSGNQDRHFSINSSSGIISMYNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHIYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGEKFSINPSGQITTLQKLDRENSTERVIAIKVMAQDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGRNADVTYSVDSVEDLEEEVIEVNPITGVVKVKESLVGLENRAFDLKIKAQDGGPPHWNSLMLLRLQVVPNEVSLPQFSEPLYTFSASEDLPEGSEIGSVKAVAGQDPVIYSLVQGTTPESNKDGIFSLDQNTGVLKVRKAMDYESTKWYQIDLMAHCPHNDTYLGSLVSVNIQVKDVNDNRPIFEADPYKAVLTENMPVGTSVIQVTANDQDTGDDGQVSYRLPVDPGSNIHELFAIDSETGWITTLQELDCETNQIYHFYVVAYDHGRTIQLSSQVLVEVSITDENDNAPRFASEDYRGSVVENSEPGEPVATLKTLDADIAEQNRQVTCYITEGDPLGQFGISQVGDEWRIFSRKTLDREHTAKYLLRITASDGKFQASVPVEIFVLDINDNSPQCSQLLYTGKVSEDVPPEHFILKVSATDLDSDTNAQITYSLHGPGADEFKLDPHTGDLTTLTALDREKKDVYSLVAKATDGGGQSCQADVTLHVEDVNDNAPRFFPSHSAVAVFDNTTVKTPVAVVLARDPDQGTNAQVVYSLTDSAEGHFSIEATTGVIRLEKPLQVRPQAALELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLSTEHSVQVPEDAQRGTEVLRLATLTRPGAEKTGYRVVSGNEQGRFRLDARTGILYVNKSLDFETSPKYFLSVECSRKGSSSLSDMTTIVVNITDINEHRPRFPQHLYSTRVLENAIVGDVVLTVSATDEDGPVNSAITYSLIGGNQLGHFAIHPKKGELQVAKALDWEQTSSYSLKLRATDSGQPALYEDTDIAIQVVDVNDNPPRFFQLNYSTSVQENAPIGSKVLQLILSDPDSPENGPPFSFRITKGNDGFAFRVTPDGWLVTTAGLSKRVQEWYKLQIEVSDSGIPPLSSSTSVKVHVREQSHYPPSALPLEIFITIGEEEFQGGMVGKIHATDRDPQDTLTYSLAGEESVGQRFSVGATDGKIIASHTLPRGRYTFNVTVSDGTFSTMAGVHVHVWHMGPEALQQTMWMGFHQLTPEELVSDHWRNLQRFLSNWLDIKRANIHLASLQPAEATAGVDVLLVFEGHLGAFSKLQELASTIARSAKEMEHSVGIQMRSAMPVVPCQGPSCQGQICQETVHLDPRVGPTYSTARLSILTPRHRLEKNCSCKGTAVRFSGQSFGRYRLPEFQNGHIHFRLKTLQSQAILLFSNKTVRLSLKLVNGVLQLEYHCPGGFYGNLSSRLHVNDHEWHSVLVEEMDTSVRLLVDSASSTSLKLPENCRGLKPERDLFLGGLVHSHSSPNVSQGFEGCLDAVVINREVLELLVHGKKAAGLLERRALTECCFPSDQCGQNPCLNGGKCSQTGGAGYICVCRPQFAGRHCEQRKENCTSTPCLEGGTCISSPEGAPCICPHPYTGDSCEMEARGCSEGHCLVTPEITRGDWGQQEILIIIVALLVIVVISTVLLFYCRRCKSHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSTSSCNNLNQTEPGKTSAPNELGTFGPSSKQRPMVCSVPPRLPPAAVSSHPDSEAIIKRRWSGEEMVYPGGATVWPPTYSGKERWEYPHSEVTPGPVPPSPHCHQNPAVMPDPSGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPPRPPSPREHLPAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVGGGHPLGRGQPQAPPNYEGSDMVESDYGSCEEVMF", "length": 4347 }, "evidence": [ { "id": "A0A8V0YP25", "url": "https://omabrowser.org/oma/group/A0A8V0YP25/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88277-1", "protein_name": "Protocadherin Fat 2", "gene_name": "Fat2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLVLLGLAILLLHRAACEKSLEETIPPLSWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLIVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRVTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTRRGKYELQVLAVDRMRKISEGNGFGNLASLVIRVEPVHRKPPAINLVVLNPPEGDEGDIYAIVTVDTNGSGAEVDSLEVVGGDPGKYFKVLRSYAQGNEFNLVAVRDINWAEHPHGFNISLQTHSWSRFPPHSIIRAFHLPSWKLANLRFEKAVYRVKLSEFSPPGSRVALVKVTTALPNLRYSLKPSSRNTAFKLNARTGLITTTKLVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPLLGVISTTKPMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDVPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTIYSLKITASDGKNYASPTTLKVTVVKDPHSEVPVQCDKTGVLTHITKTILQSAGLQSQELGEEEFTSLSNYQINHHSPQFEDHFPQSIDILEQVPINTPLARLAATDPDTGFHGKLVYVISDGNEEGCFDIELETGLLMVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDNPPRFPPGGYQLTISEDTEVGTTIAELKTEDADSEDNRRVRYTLLTPTEKFSLHPFTGELVVTGHLDRESESQYILKAEARDQPTKGHQLFSVTDLIVTLEDINDNPPQCITEHRRLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVEDAHGTFQVHPMTGALSLEKELDFERRAGYNLSFWASDSGKPLSRRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTPVMVVTAQDDDSGLDGELQYFLRAGTGLETFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVLEDAPLGTSVLQLEAWDPDSSSQGKLTFNLTSGNHLGHFIVHPFTGLLTTAKQLDRENKDEYVLEVTVQDNGDPSLRSTSRVVVCILDVNDNPPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSVTYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESYYSFTVMETDPVNHMVGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHIFMIANINHHRPQFLQDHYEIRVPQDTLPGVELLRVQATDQDHGKGLIYTILSSQDPGSANLFQLDPSSGVLVTVGTLELHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQLRYEANVPDTTAPGTELLQVRAVDADRGANAEIHYSFLKGNSDGFFNIDSLLGIITVAQRLYHVHLTRHALTVKAEDQGSPRRHDLALVVIHVHPSDSSAPVFSKDEYFIEIPESVPIGSPILLLSAGSSSEVTYELREGNKDSVFSMNSYSGLISTQKRLDHEKVPSYRLRIRGSNMAGVFTEVVALVYIIDENDNPPAFGKPTFLGHISEAAPLHSLILGEDNSPLVVRASDSDREANSLLVYKILEPEALKFFKIDPSMGTLTTTSELDFEDTPLFQFNIYVHDQGTPILFAPRSAKVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMGLLTVQAEDNDSRVTYSIKTSNADEAVTIHPTTGQISVVNPATLRLFQKFSIRASDGLYHDTAVVKISLTQVLDKSLQFDQDVYRARVTENTPHRKALVILGVHGNHLNDTLSYFLLNGTDLFHMIESAGVLQTRGGTFDREQQDTHEVAVEVRDNRVPQRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGSVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVIARDSGIPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYTTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEIFTIQELDYETHQHFRVKVRAMDKGDPPLTGETLVVVNVSDINDNPPKFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPRGQITTLQKLDRENSTERVIAIKVMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENRAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSAPEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVRKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVSIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHELFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADVSDQNRQVTCYITEGDPLGQFSISQVGDEWRISSRKTLDREHIAKYLLRVTASDGKFQASVPVEVFVVDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLTVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCDVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRASSAVELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPIFLNAEHSTQVPEDAPIDMEVLHLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAVVGDVILTVSASDDDGPVNSAITYSLVGGNQLGHFTINPKKGKLQVAKALDWEQTPSYSLRLRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTSVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAASLSKKAREWYQLHIEVSDSGLPPLSSSTLVRVQVTEQSRYPPSTLPLEISITKGEEEFQGGMIGKIHATDRDPQDTLTYSLEQEGGLDRYFTVGASDGKIIASQGLPHGRYSFNVTVSDGTFTTTTGVHVHVWHMEPEVPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNLLDVKRANIHLASLQPAEVTAGVDVLLVFERHSGTSYDLQELASAIAHSVREIEHSVGIRMRSALPVVPCQGQSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGRNCSCNGTTLRFSGQSYVQYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFSHLEYHCPGGFYGNLSSRYPVNDGQWHSMLLEERDTSVHLLVDITDNASLVIPEECQGLRTERQLLLGGLVPSNPSSNVSLGFEGCLDAVVVNGERLELLGREKKMEGRLETWALSQCCWPGTACSQSPCLNGGSCSPALGSGYLCRCPPPFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCNCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVITVALPLVIIATVGLLLYCRRRKSHKPVTMEDPDLLARSIGVDTQASPAIELDPLNTSSCNNLNQPEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAAVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKKHWEYPHPETMQGTLPPSPRRHVGPAVMPDPTGLYGGFPFPLELENKRAPLPPRYSNQNLEDLMPPRPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPATGRSQPRAPPNYEGSDMVESDYGSCEEVMF", "length": 4351 }, "evidence": [ { "id": "A0A8V0YP25", "url": "https://omabrowser.org/oma/group/A0A8V0YP25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5F226-1", "protein_name": "Protocadherin Fat 2", "gene_name": "Fat2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLVLLGVAMVLLHRAACEKPLEETITPLTWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVITLVVLNPPEGDEGDIYATVTVDTNGSGAEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDINWAEHLHGFNISLQTHSRSRFPSRSIIRAFHLPPYTLANLRFEKAVYRVKLSEFSPPGSRVALVRVTTALPTLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTVYSLKITASDGKNYASPTTLKVTVVKDPRSEVPVQCDKTGVLTHITKTILQSAGLQGQEMGEEDFTSLGNYQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDPGFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGELVVTGQLDRESEPQYILKAEARDQPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVDDVHGTFRVDPMTGALSLEKELDFERRAGYNLSFWASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDDSGLDGELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLLSTAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSITYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESHYSFAVMETDPVNHMLGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFLQDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDLHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRAVDADRGANAEVHYSFLKGNSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLAMVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYSGLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLHSLILGEDNSPLVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLFQFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDNDSKVTYSIKTSNTDEAVTIHPITGQISVVNPAALRLFPKLNIRAFDGLYQDTAVVKISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGVLQTRGVTFDREQQDTHEVAVEVRDNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGTVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEMFTIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPSGQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDEWRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNSEHSTQVPEDALIDMEVLYLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDDGPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEEFQGGMVGKIHATDRDPQDTLTYSLDREGSLGKYFTVGASDGKIIASQGLPRGRYLFNVTVSDGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLASLQPAEVTAGVDVLLAFEGHSGTSYDLQELASAIAHSAKEMEHSVGIQMRSALPVVPCQGPSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGKNCSCNGTTWRFSGQSYMRYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFLHLEYRCPGGFYGNLSSHRPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLRTERHLLLGGLVPSNPSSNVSLGFEGCLDAVVVNSERLELLGHRKKMAGYLETWALSQCCWPGTTCSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCSCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVIIVALPLLIIATVGLLLYCRRCKSHKPVAMEDPDLLARSIGVDTQASPAIELDPLNAGSCNDLNQLEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAVVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKEHWEYPHPEAMQGPLPPSPRRHVSPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPPRPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPAPGRSQPRAPPNYEGSDMVESDYGSCEEVMF", "length": 4351 }, "evidence": [ { "id": "A0A8V0YP25", "url": "https://omabrowser.org/oma/group/A0A8V0YP25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYQ8-1", "protein_name": "Protocadherin Fat 2", "gene_name": "FAT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTIALLGFAIFLLHCATCEKPLEGILSSSAWHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPPDSNDGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPAFPNLQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSPGQASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSDEEAFSIDLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVEGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSEVNYSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIRASDGLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQGLPRGHYSFNVTVSDGTFTTTAGVHVYVWHVGQEALQQAMWMGFYQLTPEELVSDHWRNLQRFLSHKLDIKRANIHLASLQPAEAVAGVDVLLVFEGHSGTFYEFQELASIITHSAKEMEHSVGVQMRSAMPMVPCQGPTCQGQICHNTVHLDPKVGPTYSTARLSILTPRHHLQRSCSCNGTATRFSGQSYVRYRAPAARNWHIHFYLKTLQPQAILLFTNETASVSLKLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLGGLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRCKSHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVIKRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPSRPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGSCEEVMF", "length": 4349 }, "evidence": [ { "id": "A0A8V0YP25", "url": "https://omabrowser.org/oma/group/A0A8V0YP25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" }, { "name": "epithelial cell migration", "id": "GO:0010631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP25" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": 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"table_stats": [ { "field": "total", "count": 197 }, { "field": "total_sites", "count": 146 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPL7-1", "uniprot_ac": "A0A8V0YPL7", "uniprot_id": "A0A8V0YPL7_CHICK", "mass": { "chemical_mass": 38885.0, "monoisotopic_mass": 38885.0 }, "refseq": { "ac": "XP_040516512", "name": "peroxisomal membrane protein PMP34 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516512" }, "gene_names": [ { "name": "SLC25A17", "type": "recommended", "evidence": [ { "id": "A0A8V0YPL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ] }, { "name": "SLC25A17", "type": "synonym", "evidence": [ { "id": "XP_040516512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516512" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 17", "type": "synonym", "evidence": [ { "id": "A0A8V0YPL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal membrane protein PMP34 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040516512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516512" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040516512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516512" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7", "locus": { "chromosome": "1", "start_pos": 49985603, "end_pos": 49966637, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012962", "url": "https://www.ensembl.org/id/ENSGALG00010012962" } ] } } ], "crossref": [ { "id": "A0A8V0YPL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "418004", "url": "https://www.ncbi.nlm.nih.gov/gene/418004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418004", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418004", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFMMYEL", "url": "https://omabrowser.org/oma/group/QFMMYEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHS7", "url": "https://www.orthodb.org/?gene=A0A8V0YHS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPL7", "url": "https://www.orthodb.org/?gene=A0A8V0YPL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45939:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45939:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-389599", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040516512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGRKFLKLEEVKIQTGMNSEPPREDKSRRSQKRASEQMVDTYKCLGKQVNIKGSVTAMTVFFPLDTARLRLQVDEKRKSKTTPAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTLWVKGQHSSTGKDLVLGVVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGALALWNGTFPSLLLVFNPAIQFMFYEGFKRKLLKKQTQLTSLDAFVMGAVAKAVATTLTYPLQTVQSILRFGRHRLNPENRTLGSLKNVLYLLRERVRRFGLMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFRVMGLKHSRAH", "length": 343, "header": "tr|A0A8V0YPL7-1|A0A8V0YPL7_CHICK Isoform 1 of Solute carrier family 25 member 17 OS=Gallus gallus OX=9031 GN=SLC25A17 PE=1 SV=1 CANONICAL=A0A8V0YPL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS7/entry", "sequence": { "sequence": "MARVGATVDKLELRATAASQPEPTRAAAMSSVVSYESLVHAVSGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTPAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTLWVKGQHSSTGKDLVLGVVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGALALWNGTFPSLLLVFNPAIQFMFYEGFKRKLLKKQTQLTSLDAFVMGAVAKAVATTLTYPLQTVQSILRFGRHRLNPENRTLGSLKNVLYLLRERVRRFGLMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFRVMGLKHSRAH", "length": 335, "header": "tr|A0A8V0YHS7-1|A0A8V0YPL7_CHICK Computationally mapped isoform of Solute carrier family 25 member 17 OS=Gallus gallus OX=9031 GN=SLC25A17 PE=1 SV=1 CANONICAL=A0A8V0YPL7-1" }, "locus": { "chromosome": "1", "start_pos": 49984388, "end_pos": 49970748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031097.1", "url": "https://www.ensembl.org/id/ENSGALT00010031097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018090.1", "url": "https://www.ensembl.org/id/ENSGALP00010018090.1" } ] } }, { "isoform_ac": "A0A8V0YPL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7/entry", "sequence": { "sequence": "MSLGRKFLKLEEVKIQTGMNSEPPREDKSRRSQKRASEQMVDTYKCLGKQVNIKGSVTAMTVFFPLDTARLRLQVDEKRKSKTTPAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTLWVKGQHSSTGKDLVLGVVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGALALWNGTFPSLLLVFNPAIQFMFYEGFKRKLLKKQTQLTSLDAFVMGAVAKAVATTLTYPLQTVQSILRFGRHRLNPENRTLGSLKNVLYLLRERVRRFGLMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFRVMGLKHSRAH", "length": 343, "header": "tr|A0A8V0YPL7-1|A0A8V0YPL7_CHICK Isoform 1 of Solute carrier family 25 member 17 OS=Gallus gallus OX=9031 GN=SLC25A17 PE=1 SV=1 CANONICAL=A0A8V0YPL7-1" }, "locus": { "chromosome": "1", "start_pos": 49984388, "end_pos": 49967899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031100.1", "url": "https://www.ensembl.org/id/ENSGALT00010031100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018094.1", "url": "https://www.ensembl.org/id/ENSGALP00010018094.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418004", "resource": "KEGG Pathway" }, { "id": "R-GGA-389599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389599", "resource": "Reactome", "description": "Alpha-oxidation of phytanate" }, { "id": "R-GGA-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B1G7-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "SLC25A17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASVLSYENLVHAVAGAVGSMTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQHSTTGKDLIVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYSGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTATTFMVMGLKRASKH", "length": 307 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IGY2-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "Slc25a17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKTVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLYLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH", "length": 307 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O04200-1", "protein_name": "Peroxisomal nicotinamide adenine dinucleotide carrier", "gene_name": "PXN", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDALINGLAGAGGGIIAQLLTYPLQTVNTRQQTERDLKREKRKLGTIEHMCQVVKQEGWERLYGGLAPSLAGTAASQGVYYYFYQVFRNRAEATALARKKKGLGDGSVGMFASLLVAAFAGSVNVLMTNPIWVIVTRMQTHRKMTKDQTAAPESPSSNAEALVAVEPRPYGTFNTIREVYDEAGITGFWKGVIPTLIMVSNPSMQFMLYETMLTKLKKKRALKGSNNVTALETFLLGAVAKLGATVTTYPLLVVKSRLQAKQVTTGDKRQQYKGTLDAILKMIRYEGLYGFYKGMSTKIVQSVLAAAVLFMIKEELVKGAKLLLSNATSS", "length": 331 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O43808-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "SLC25A17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKRAHQH", "length": 307 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70579-1", "protein_name": "Peroxisomal membrane protein PMP34", "gene_name": "Slc25a17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRSSTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAIAKAIATTVTYPMQTVQSILRFGRHRLNPENRTLGSLRNVLSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKSTHKH", "length": 307 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76P23-1", "protein_name": "Mitochondrial substrate carrier family protein Q", "gene_name": "mcfQ", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEKIHITQNSGNVDHTVEALGHAISGGVAGMAAIALTYPFSTVSTRLQVQQKKQQQGQQSEITTVPYKNSIDAFKRIIKEENWRTLYSGLKSALIGIGASSFVYYYWYTLLKSISLKLKNKQELGTIENLAIAALAGCANVLTTLPIWVVNTRLQINSDKGIVGQFKYIIKNEGFGGLYKGLIPALILVSNPSVQFVSYEKLRALWRRQSGRTKLGGLEVFILGAIAKLIAGIVTYPYLLVKSRLQSQSGNASNPESQQQQYKGTLDAIGKIFKSDGFLGFFKGMPSKMVQTVIGAAFMFLVKDKVVIHAVAILFYLKRLLNKNNKRV", "length": 329 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VZD9-1", "protein_name": "Peroxisomal membrane protein 34, isoform A", "gene_name": "PMP34", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVAPSKLSQVLSYQNFVHAVSGAAGGCIAMSTFYPLDTVRSRLQLEEAGDVRSTRQVIKEIVLGEGFQSLYRGLGPVLQSLCISNFVYFYTFHALKAVASGGSPSQHSALKDLLLGSIAGIINVLTTTPFWVVNTRLRMRNVAGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLMLVSNPALQFMMYEMLKRNIMRFTGGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGSTPRTESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIAGTVGMLLKRN", "length": 314 }, "evidence": [ { "id": "A0A8V0YPL7", "url": "https://omabrowser.org/oma/group/A0A8V0YPL7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "ADP transmembrane transporter activity", "id": "GO:0015217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "coenzyme A transmembrane transporter activity", "id": "GO:0015228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "FMN transmembrane transporter activity", "id": "GO:0044610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044610", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "NAD transmembrane transporter activity", "id": "GO:0051724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "AMP transmembrane transporter activity", "id": "GO:0080122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" }, { "name": "FAD transmembrane transporter activity", "id": "GO:0015230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN43-1", "uniprot_ac": "A0A8V0YN43", "uniprot_id": "A0A8V0YN43_CHICK", "mass": { "chemical_mass": 66548.0, "monoisotopic_mass": 66548.0 }, "refseq": { "ac": "NP_990617", "name": "lamin-B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617" }, "gene_names": [ { "name": "LMNB1", "type": "recommended", "evidence": [ { "id": "A0A8V0YN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ] }, { "name": "LMNB1", "type": "synonym", "evidence": [ { "id": "NP_990617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617" } ] }, { "name": "lamin-B1", "type": "synonym", "evidence": [ { "id": "NP_990617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617" } ] } ], "protein_names": [ { "name": "Lamin-B1", "type": "recommended", "evidence": [ { "id": "A0A8V0YN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43/entry#names_and_taxonomy" } ] }, { "name": "lamin-B1", "type": "synonym", "evidence": [ { "id": "NP_990617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.93933.1, SRR13267658.14377.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000095.1. On Sep 23, 2021 this sequence version replaced NP_990617.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMNB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43", "locus": { "chromosome": "Z", "start_pos": 57046581, "end_pos": 57021023, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012607", "url": "https://www.ensembl.org/id/ENSGALG00010012607" } ] } } ], "crossref": [ { "id": "A0A8V0YN43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN43", "database": "AlphaFoldDB", "categories": [] }, { "id": "396223", "url": "https://www.ncbi.nlm.nih.gov/gene/396223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396223", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYEMIKT", "url": "https://omabrowser.org/oma/group/GYEMIKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIA8", "url": "https://www.orthodb.org/?gene=A0A8V0YIA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN37", "url": "https://www.orthodb.org/?gene=A0A8V0YN37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN43", "url": "https://www.orthodb.org/?gene=A0A8V0YN43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45721:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45721:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2559584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-352238", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352238", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVAPLSPQPRGAAASAALSPTRISRLQEKEELRQLNDRLAVYIDKVRSLETENSALQRRVSEREQVCGREISGLKELFETELADARKTLDDTARERAKLQIELGKLRAEHEQVLSSYAKKDSDLNAAQVKLREFEAALNAKEAALATALGDKRSQEEELEDLRDQIAQLEVSLAAAKKELADETLQKVDLENRCQSLIEDLEFRKNMYEEEIKETRRKHETRLVEVDSGRQIEYEYKLAQALKEIREQHDAQVKLYKEELEQTYSSKLENIRQSSEMHSCTANTVREELHESRMRIETLSSHIADIQKESRAWQDRVHELEDTLSKERENYRKILAENEREVAEMRNQMQQQFSDYEQLLDVKLALDMEISAYRKLLESEEERLRLSPGPSSRVTVSRASSSRSVRTTRGKRKRIDVEESEASSSVSISHSASATGNISIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSASYRYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTVNEGEEEEEEGEEEILEDVIHQQGSPRKPDRSCVVM", "length": 584, "header": "tr|A0A8V0YN43-1|A0A8V0YN43_CHICK Isoform 1 of Lamin-B1 OS=Gallus gallus OX=9031 GN=LMNB1 PE=1 SV=1 CANONICAL=A0A8V0YN43-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA8/entry", "sequence": { "sequence": "MAAAVAPLSPQPRGAAASAALSPTRISRLQEKEELRQLNDRLAVYIDKVRSLETENSALQRRVSEREQVLSSYAKKDSDLNAAQVKLREFEAALNAKEAALATALGDKRSQEEELEDLRDQIAQLEVSLAAAKKELADETLQKVDLENRCQSLIEDLEFRKNMYEEEIKETRRKHETRLVEVDSGRQIEYEYKLAQALKEIREQHDAQVKLYKEELEQTYSSKLENIRQSSEMHSCTANTVREELHESRMRIETLSSHIADIQKESRAWQDRVHELEDTLSKERENYRKILAENEREVAEMRNQMQQQFSDYEQLLDVKLALDMEISAYRKLLESEEERLRLSPGPSSRVTVSRASSSRSVRTTRGKRKRIDVEESEASSSVSISHSASATGNISIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSASYRYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTVNEGEEEEEEGEEEILEDVIHQQGSPRKPDRSCVVM", "length": 537, "header": "tr|A0A8V0YIA8-1|A0A8V0YN43_CHICK Computationally mapped isoform of Lamin-B1 OS=Gallus gallus OX=9031 GN=LMNB1 PE=1 SV=1 CANONICAL=A0A8V0YN43-1" }, "locus": { "chromosome": "Z", "start_pos": 57044008, "end_pos": 57021204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030205.1", "url": "https://www.ensembl.org/id/ENSGALT00010030205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017536.1", "url": "https://www.ensembl.org/id/ENSGALP00010017536.1" } ] } }, { "isoform_ac": "A0A8V0YN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN37/entry", "sequence": { "sequence": "MAAAVAPLSPQPRGAAASAALSPTRISRLQEKEELRQLNDRLAVYIDKVRSLETENSALQRRVSEREQVCGREISGLKELFETELADARKTLDDTARERAKLQIELGKLRAEHEQVLSSYAKKDSDLNAAQVKLREFEAALNAKEAALATALGDKRSQEEELEDLRDQIAQLEVSLAAAKKELADETLQKVDLENRCQSLIEDLEFRKNMYEEEIKETRRKHETRLVEVDSGRQIEYEYKLAQALKEIREQHDAQVKLYKEELEQTYSSKLENIRQSSEMHSCTANTVREELHESRMRIETLSSHIADIQKESRAWQDRVHELEDTLSKERENYRKILAENEREVAEMRNQMQQQFSDYEQLLDVKLALDMEISAYRKLLESEEERLRLSPGPSSRVTVSRASSSRSVRTTRGKRKRIDVEESEASSSVSISHSASATGNISIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSASYRYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEPKET", "length": 540, "header": "tr|A0A8V0YN37-1|A0A8V0YN37_CHICK Computationally mapped isoform of Lamin B1 OS=Gallus gallus OX=9031 GN=LMNB1 PE=1 SV=1 CANONICAL=A0A8V0YN43-1" }, "locus": { "chromosome": "Z", "start_pos": 57043986, "end_pos": 57021204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030200.1", "url": "https://www.ensembl.org/id/ENSGALT00010030200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017534.1", "url": "https://www.ensembl.org/id/ENSGALP00010017534.1" } ] } }, { "isoform_ac": "A0A8V0YN43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43/entry", "sequence": { "sequence": "MAAAVAPLSPQPRGAAASAALSPTRISRLQEKEELRQLNDRLAVYIDKVRSLETENSALQRRVSEREQVCGREISGLKELFETELADARKTLDDTARERAKLQIELGKLRAEHEQVLSSYAKKDSDLNAAQVKLREFEAALNAKEAALATALGDKRSQEEELEDLRDQIAQLEVSLAAAKKELADETLQKVDLENRCQSLIEDLEFRKNMYEEEIKETRRKHETRLVEVDSGRQIEYEYKLAQALKEIREQHDAQVKLYKEELEQTYSSKLENIRQSSEMHSCTANTVREELHESRMRIETLSSHIADIQKESRAWQDRVHELEDTLSKERENYRKILAENEREVAEMRNQMQQQFSDYEQLLDVKLALDMEISAYRKLLESEEERLRLSPGPSSRVTVSRASSSRSVRTTRGKRKRIDVEESEASSSVSISHSASATGNISIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSASYRYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTVNEGEEEEEEGEEEILEDVIHQQGSPRKPDRSCVVM", "length": 584, "header": "tr|A0A8V0YN43-1|A0A8V0YN43_CHICK Isoform 1 of Lamin-B1 OS=Gallus gallus OX=9031 GN=LMNB1 PE=1 SV=1 CANONICAL=A0A8V0YN43-1" }, "locus": { "chromosome": "Z", "start_pos": 57044008, "end_pos": 57021204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030211.1", "url": "https://www.ensembl.org/id/ENSGALT00010030211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017539.1", "url": "https://www.ensembl.org/id/ENSGALP00010017539.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396223", "resource": "KEGG Pathway" }, { "id": "R-GGA-2559584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "resource": "Reactome", "description": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" }, { "id": "R-GGA-352238", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352238", "resource": "Reactome", "description": "Breakdown of the nuclear lamina" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RKM0-1", "protein_name": "Lamin-B1", "gene_name": "LMNB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATATPVQSRTGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLESDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVKLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAEVAVEEELFHQQGAPRGSNRSCAIM", "length": 586 }, "evidence": [ { "id": "A0A8V0YN43", "url": "https://omabrowser.org/oma/group/A0A8V0YN43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P14733-1", "protein_name": "Lamin-B1", "gene_name": "Lmnb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVEEERFHQQGAPRASNKSCAIM", "length": 588 }, "evidence": [ { "id": "A0A8V0YN43", "url": "https://omabrowser.org/oma/group/A0A8V0YN43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20700-1", "protein_name": "Lamin-B1", "gene_name": "LMNB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM", "length": 586 }, "evidence": [ { "id": "A0A8V0YN43", "url": "https://omabrowser.org/oma/group/A0A8V0YN43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70615-1", "protein_name": "Lamin-B1", "gene_name": "Lmnb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATATPVQQRAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLEEERFHQQGTPRASNKSCAIM", "length": 587 }, "evidence": [ { "id": "A0A8V0YN43", "url": "https://omabrowser.org/oma/group/A0A8V0YN43/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "lamin filament", "id": "GO:0005638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005638", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein localization to nuclear envelope", "id": "GO:0090435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" }, { "name": "structural constituent of nuclear lamina", "id": "GO:0160123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 387, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN43" }, { "id": "PS51841", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LTD", "eco_id": "ECO_0000259", "start_pos": 429, "end_pos": 545, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 440, "end_pos": 442 }, { "start_pos": 457, "end_pos": 459 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQC4-1", "uniprot_ac": "A0A8V0YQC4", "uniprot_id": "A0A8V0YQC4_CHICK", "mass": { "chemical_mass": 81788.0, "monoisotopic_mass": 81788.0 }, "refseq": {}, "gene_names": [ { "name": "TARS", "type": "recommended", "evidence": [ { "id": "A0A8V0YQC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ] } ], "protein_names": [ { "name": "threonine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "A0A8V0YQC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.3", "type": "synonym", "evidence": [ { "id": "A0A8V0YQC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4/entry#names_and_taxonomy" } ] }, { "name": "Threonyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "A0A8V0YQC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4#function" }, { "database": "UniProtKB", "id": "ARBA00058080", "url": "https://www.uniprot.org/uniprotkb/ARBA00058080#function" }, { "database": "UniProtKB", "id": "A0A8V0YII0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII0#function" }, { "database": "UniProtKB", "id": "A0A8V0YQC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TARS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4", "locus": { "chromosome": "Z", "start_pos": 10671538, "end_pos": 10656308, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013116", "url": "https://www.ensembl.org/id/ENSGALG00010013116" } ] } } ], "crossref": [ { "id": "A0A8V0YQC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01667", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01667", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YII0", "url": "https://www.orthodb.org/?gene=A0A8V0YII0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQC4", "url": "https://www.orthodb.org/?gene=A0A8V0YQC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQC8", "url": "https://www.orthodb.org/?gene=A0A8V0YQC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11451:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11451:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03129", "url": 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"header": "tr|A0A8V0YQC4-1|A0A8V0YQC4_CHICK Isoform 1 of threonine--tRNA ligase OS=Gallus gallus OX=9031 GN=TARS PE=1 SV=1 CANONICAL=A0A8V0YQC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YII0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII0/entry", "sequence": { "sequence": "MAGADGQLNPWPAFINERLEMYNKLKAEHDALLAERAANDSKPIKVTLPDGKLVDAESWKTTPYQIACGISQGLADNTVIAKVNKMVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERIYGGCLCYGPPIENGFYYDMFLEDGGVSSNDFSALETLCKKIMKEKQPFERLEVKKETLLEMFKYNKFKCRILNEKVSTPTTTVYRCGPLIDLCRGPHVRHTGKIKSIKIHKNSSTYWEGKADMETLQRIYGISFPDAKMLKEWEKFQEEAKNRDHRKIGRDQELFFFHELSPGSCFFLPKGAYIYNTLIEFIRSEYRKRGFQEVVTPNIFNSKLWMTSGHWQHYSENMFSFEVEKEIFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCSVEQIEEEIKSCLQFLRAVYDVFGFSFKLNLSTRPEKYLGDIEVWNRAEKQLENSLNDFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLSIRFNLTFVSHDGNDKTRPVIIHRAILGSVERMIAILTENYGGKWPLWLSPQQVMVVPVGPTCDEYAQKVRQQFHDAGLMADIDVDPGCTLNKKIRNAQLAQYNFILVVGEKEKASGTVNIRTRDNKVHGERTIADTVKRLLELKCSRSKQAEEEF", "length": 684, "header": "tr|A0A8V0YII0-1|A0A8V0YQC4_CHICK Computationally mapped isoform of threonine--tRNA ligase OS=Gallus gallus OX=9031 GN=TARS PE=1 SV=1 CANONICAL=A0A8V0YQC4-1" }, "locus": { "chromosome": "Z", "start_pos": 10670606, "end_pos": 10656328, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031438.1", "url": "https://www.ensembl.org/id/ENSGALT00010031438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018354.1", "url": "https://www.ensembl.org/id/ENSGALP00010018354.1" } ] } }, { "isoform_ac": "A0A8V0YQC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4/entry", "sequence": { "sequence": "MAGADGQVNAGEEKKADCGKKKMKEASGDEGRAELNPWPAFINERLEMYNKLKAEHDALLAERAANDSKPIKVTLPDGKLVDAESWKTTPYQIACGISQGLADNTVIAKVNKMVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERIYGGCLCYGPPIENGFYYDMFLEDGGVSSNDFSALETLCKKIMKEKQPFERLEVKKETLLEMFKYNKFKCRILNEKVSTPTTTVYRCGPLIDLCRGPHVRHTGKIKSIKIHKNSSTYWEGKADMETLQRIYGISFPDAKMLKEWEKFQEEAKNRDHRKIGRDQELFFFHELSPGSCFFLPKGAYIYNTLIEFIRSEYRKRGFQEVVTPNIFNSKLWMTSGHWQHYSENMFSFEVEKEIFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCSVEQIEEEIKSCLQFLRAVYDVFGFSFKLNLSTRPEKYLGDIEVWNRAEKQLENSLNDFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLSIRFNLTFVSHDGNDKTRPVIIHRAILGSVERMIAILTENYGGKWPLWLSPQQVMVVPVGPTCDEYAQKVRQQFHDAGLMADIDVDPGCTLNKKIRNAQLAQYNFILVVGEKEKASGTVNIRTRDNKVHGERTIADTVKRLLELKCSRSKQAEEEF", "length": 711, "header": "tr|A0A8V0YQC4-1|A0A8V0YQC4_CHICK Isoform 1 of threonine--tRNA ligase OS=Gallus gallus OX=9031 GN=TARS PE=1 SV=1 CANONICAL=A0A8V0YQC4-1" }, "locus": { "chromosome": "Z", "start_pos": 10670606, "end_pos": 10656328, "strand": "-", "evidence": [ { "database": 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"MAGADGQVNAGEEKKADCGKKKMKEASGDEGRAELNPWPAFINERLEMYNKLKAEHDALLAERAANDSKPIKVTLPDGKLVDAESWKTTPYQIACGISQGLADNTVIAKVNKMVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERIYGGCLCYGPPIENGFYYDMFLEDGGVSSNDFSALETLCKKIMKEKQPFERLEVKKETLLEMFKYNKFKCRILNEKVSTPTTTVYRCGPLIDLCRGPHVRHTGKIKSIKIHKNSSTYWEGKADMETLQRIYGISFPDAKMLKEWEKFQEEAKNRDHRKIGRDQELFFFHELSPGSCFFLPKGAYIYNTLIEFIRSEYRKRGFQEVVTPNIFNSKLWMTSGHWQHYSENMFSFEVEKEIFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCSVEQIEEEIKSCLQFLRAVYDVFGFSFKLNLSTRPEKYLGDIEVWNRAEKQLENSLNDFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLSIRFNLTFVRPLWLSPQQVMVVPVGPTCDEYAQKVRQQFHDAGLMADIDVDPGCTLNKKIRNAQLAQYNFILVVGEKEKASGTVNIRTRDNKVHGERTIADTVKRLLELKCSRSKQAEEEF", "length": 676, "header": "tr|A0A8V0YQC8-1|A0A8V0YQC8_CHICK Computationally mapped isoform of threonine--tRNA ligase OS=Gallus gallus OX=9031 GN=TARS PE=1 SV=1 CANONICAL=A0A8V0YQC4-1" }, "locus": { "chromosome": "Z", "start_pos": 10670606, "end_pos": 10656328, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031454.1", "url": "https://www.ensembl.org/id/ENSGALT00010031454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018363.1", "url": "https://www.ensembl.org/id/ENSGALP00010018363.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 617, "start_aa": "Thr", "end_pos": 617, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr617", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" }, { "name": "threonine-tRNA ligase activity", "id": "GO:0004829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "threonyl-tRNA aminoacylation", "id": "GO:0006435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, 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"https://www.orthodb.org/?gene=A0A8V0YJ85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT6", "url": "https://www.orthodb.org/?gene=A0A8V0YLT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLU2", "url": "https://www.orthodb.org/?gene=A0A8V0YLU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12232:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12232:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LSALPPRFSRCPIPTCSARSSVLRASPPRGPPGQIKSQQSEVTRILDGKNIKYELVDISQDNALREEMRAKAGNPKAIPPQIVNGDHYCGDYELFVEAVEQNTLQEFLKLA", "length": 111, "header": "tr|A0A8V0YLT6-1|A0A8V0YLT6_CHICK Isoform 1 of SH3 domain-binding glutamic acid-rich-like protein 3 OS=Gallus gallus OX=9031 GN=SH3BGRL3 PE=1 SV=1 CANONICAL=A0A8V0YLT6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ85/entry", "sequence": { "sequence": "SDVLSVRSPFGAPPRVPITLPLPPDFQIKSQQSEVTRILDGKNIKYELVDISQDNALREEMRAKAGNPKAIPPQIVNGDHYCGDYELFVEAVEQNTLQEFLKLA", "length": 104, "header": "tr|A0A8V0YJ85-1|A0A8V0YLT6_CHICK Computationally mapped isoform of SH3 domain-binding glutamic acid-rich-like protein 3 OS=Gallus gallus OX=9031 GN=SH3BGRL3 PE=1 SV=1 CANONICAL=A0A8V0YLT6-1" }, "locus": { "chromosome": "23", "start_pos": 593541, "end_pos": 592839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032088.1", "url": "https://www.ensembl.org/id/ENSGALT00010032088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018878.1", "url": "https://www.ensembl.org/id/ENSGALP00010018878.1" } ] } }, { "isoform_ac": "A0A8V0YLT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6/entry", "sequence": { "sequence": "LSALPPRFSRCPIPTCSARSSVLRASPPRGPPGQIKSQQSEVTRILDGKNIKYELVDISQDNALREEMRAKAGNPKAIPPQIVNGDHYCGDYELFVEAVEQNTLQEFLKLA", "length": 111, "header": "tr|A0A8V0YLT6-1|A0A8V0YLT6_CHICK Isoform 1 of SH3 domain-binding glutamic acid-rich-like protein 3 OS=Gallus gallus OX=9031 GN=SH3BGRL3 PE=1 SV=1 CANONICAL=A0A8V0YLT6-1" }, "locus": { "chromosome": "23", "start_pos": 593649, "end_pos": 592839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032075.1", "url": "https://www.ensembl.org/id/ENSGALT00010032075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018865.1", "url": "https://www.ensembl.org/id/ENSGALP00010018865.1" } ] } }, { "isoform_ac": "A0A8V0YLU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU2/entry", "sequence": { "sequence": "MSTLKVYSTSVTGSRESEVTRILDGKNIKYELVDISQDNALREEMRAKAGNPKAIPPQIVNGDHYCGVRLRGRRYCESWMVGYNVIPLVLPQMPSGCFPKGASSVLRG", "length": 108, "header": "tr|A0A8V0YLU2-1|A0A8V0YLT6_CHICK Computationally mapped isoform of SH3 domain-binding glutamic acid-rich-like protein 3 OS=Gallus gallus OX=9031 GN=SH3BGRL3 PE=1 SV=1 CANONICAL=A0A8V0YLT6-1" }, "locus": { "chromosome": "23", "start_pos": 593815, "end_pos": 593170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032080.1", "url": "https://www.ensembl.org/id/ENSGALT00010032080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018870.1", "url": "https://www.ensembl.org/id/ENSGALP00010018870.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQM9-1", "uniprot_ac": "A0A8V0YQM9", "uniprot_id": "A0A8V0YQM9_CHICK", "mass": { "chemical_mass": 44918.0, "monoisotopic_mass": 44918.0 }, "refseq": {}, "gene_names": [ { "name": "SPO11", "type": "recommended", "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ] } ], "protein_names": [ { "name": "DNA topoisomerase (ATP-hydrolyzing)", "type": "recommended", "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9/entry#names_and_taxonomy" } ] }, { "name": "Meiotic recombination protein SPO11-3", "type": "synonym", "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPO11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9", "locus": { "chromosome": "20", "start_pos": 11988914, "end_pos": 12001264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015026", "url": "https://www.ensembl.org/id/ENSGALG00010015026" } ] } } ], "crossref": [ { "id": "A0A8V0YQM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ90", "url": "https://www.orthodb.org/?gene=A0A8V0YJ90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM9", "url": "https://www.orthodb.org/?gene=A0A8V0YQM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSD0", "url": "https://www.orthodb.org/?gene=A0A8V0YSD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10848:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10848:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJ90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSVSPSHSVGKLGGCAVPAMEERGAEALSGHEDGSKETRVSAHGSHVPSSEVLEAIENVILDVLKSLAKKKAPVLTLANRSDWRNIEFKDSVGLQMIPHSSTKQIRSDCPATAPKFAMMLKILSMIYKMVQSNSYATKRDIYYSDKLLFGSQRVVDNLINEISCMLQIPRRSLHILSTTRGFVAGNLSYTEEDGTKVNCTCGATAVTVPSNVQGIKNLYSHAKFILIVEKDATFQRLLDDEFCIKLAPCIMITGRGIPDLNTRLLVRKLWDTFQIPIFTLMDADPHGVEIMCIYKYGSVSMSFEAHQLTVPCIKWLGLLPSDIKRLNIRKDVLIPFTKQDQNKLASLQKRPYIACQPVWKKELEIMAASKMKAEIQVLTSLSSDYLSRVYLPNKLQFCGWI", "length": 402, "header": "tr|A0A8V0YQM9-1|A0A8V0YQM9_CHICK Isoform 1 of DNA topoisomerase (ATP-hydrolyzing) OS=Gallus gallus OX=9031 GN=SPO11 PE=3 SV=1 CANONICAL=A0A8V0YQM9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ90/entry", "sequence": { "sequence": "MEERGAEALSGHEDGSKETRVSAHGSHVPSSEVLEAIENVILDVLKSLAKKKAPVLTLANRSDWRNIEFKDSVGLQMIPHSSTKQIRSDCPATAPKFAMMLKILSMIYKMVQSNSYATKRDIYYSDKLLFGSQRVVDNLINEISCMLQIPRRSLHILSTTRGFVAGNLSYTEEDGTKVNCTCGATAVTVPSNVQGIKKKDATFQRLLDDEFCIKLAPCIMITGRGIPDLNTRLLVRKLWDTFQIPIFTLMDADPHGVEIMCIYKYGSVSMSFEAHQLTVPCIKWLGLLPSDIKRLNIRKDVLIPFTKQDQNKLASLQKRPYIACQPVWKKEVCPNLLFPISYSPQDKSYHPQSCSFLLL", "length": 359, "header": "tr|A0A8V0YJ90-1|A0A8V0YQM9_CHICK Computationally mapped isoform of DNA topoisomerase (ATP-hydrolyzing) OS=Gallus gallus OX=9031 GN=SPO11 PE=3 SV=1 CANONICAL=A0A8V0YQM9-1" }, "locus": { "chromosome": "20", "start_pos": 12000805, "end_pos": 11989892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036132.1", "url": "https://www.ensembl.org/id/ENSGALT00010036132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020991.1", "url": "https://www.ensembl.org/id/ENSGALP00010020991.1" } ] } }, { "isoform_ac": "A0A8V0YQM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9/entry", "sequence": { "sequence": "MQSVSPSHSVGKLGGCAVPAMEERGAEALSGHEDGSKETRVSAHGSHVPSSEVLEAIENVILDVLKSLAKKKAPVLTLANRSDWRNIEFKDSVGLQMIPHSSTKQIRSDCPATAPKFAMMLKILSMIYKMVQSNSYATKRDIYYSDKLLFGSQRVVDNLINEISCMLQIPRRSLHILSTTRGFVAGNLSYTEEDGTKVNCTCGATAVTVPSNVQGIKNLYSHAKFILIVEKDATFQRLLDDEFCIKLAPCIMITGRGIPDLNTRLLVRKLWDTFQIPIFTLMDADPHGVEIMCIYKYGSVSMSFEAHQLTVPCIKWLGLLPSDIKRLNIRKDVLIPFTKQDQNKLASLQKRPYIACQPVWKKELEIMAASKMKAEIQVLTSLSSDYLSRVYLPNKLQFCGWI", "length": 402, "header": "tr|A0A8V0YQM9-1|A0A8V0YQM9_CHICK Isoform 1 of DNA topoisomerase (ATP-hydrolyzing) OS=Gallus gallus OX=9031 GN=SPO11 PE=3 SV=1 CANONICAL=A0A8V0YQM9-1" }, "locus": { "chromosome": "20", "start_pos": 12001137, "end_pos": 11989642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036129.1", "url": "https://www.ensembl.org/id/ENSGALT00010036129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020988.1", "url": "https://www.ensembl.org/id/ENSGALP00010020988.1" } ] } }, { "isoform_ac": "A0A8V0YSD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD0/entry", "sequence": { "sequence": "MSMSFEAHQLTVPCIKWLGLLPSDIKRLNIRKDVLIPFTKQDQNKLASLQKRPYIACQPVWKKELEIMAASKMKAEIQVLTSLSSDYLSRVYLPNKLQFCGWI", "length": 103, "header": "tr|A0A8V0YSD0-1|A0A8V0YQM9_CHICK Computationally mapped isoform of DNA topoisomerase (ATP-hydrolyzing) OS=Gallus gallus OX=9031 GN=SPO11 PE=3 SV=1 CANONICAL=A0A8V0YQM9-1" }, "locus": { "chromosome": "20", "start_pos": 11990552, "end_pos": 11989642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036125.1", "url": "https://www.ensembl.org/id/ENSGALT00010036125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020984.1", "url": "https://www.ensembl.org/id/ENSGALP00010020984.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity", "id": "GO:0003918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003918", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "nuclear chromosome", "id": "GO:0000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break processing", "id": "GO:0000706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" }, { "id": "PF04406", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spo11/DNA topoisomerase VI subunit A N-terminal", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 176, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM9" }, { "id": "PF21180", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Topoisomerase 6 subunit A/Spo11 TOPRIM", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 396, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.6.2.2", "ec_name": "ATP-dependent breakage, passage and rejoining of double-stranded DNA.", "evidence": [ { "id": "5.6.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.6.2.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPF3-1", "uniprot_ac": "A0A8V0YPF3", "uniprot_id": "A0A8V0YPF3_CHICK", "mass": { "chemical_mass": 36489.0, "monoisotopic_mass": 36489.0 }, "refseq": { "ac": "NP_001383301", "name": "GLI pathogenesis related 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301" }, "gene_names": [ { "name": "GLIPR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3" } ] }, { "name": "GLIPR1", "type": "synonym", "evidence": [ { "id": "NP_001383301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301" } ] } ], "protein_names": [ { "name": "GLI pathogenesis related 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001383301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301" } ] }, { "name": "GLI pathogenesis-related 1 (glioma)", "type": "synonym", "evidence": [ { "id": "NP_001383301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301" } ] }, { "name": "GLI pathosis related 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.166868.1, SRR12888544.252640.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLIPR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3", "locus": { "chromosome": "1", "start_pos": 37893161, "end_pos": 37882443, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012924", "url": "https://www.ensembl.org/id/ENSGALG00010012924" } ] } } ], "crossref": [ { "id": "A0A8V0YPF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427869", "url": "https://www.ncbi.nlm.nih.gov/gene/427869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RHRNTEY", "url": "https://omabrowser.org/oma/group/RHRNTEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJL3", "url": "https://www.orthodb.org/?gene=A0A8V0YJL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPF3", "url": "https://www.orthodb.org/?gene=A0A8V0YPF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001383301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKITFFFALLFMCELFVCHHTYEQYPLPDIEDAKFIEDCVRAHNDFRSKVNPPASNMLRMSWDPALAKSAKAWAKRCMFEHNMYLKIPQKMHPTFPSIGENIWTGTATIFSVHTALTDWFDEVKSYDFNTRRCSDMCGHYTQVVWATSYKVGCAVHFCHRIHNLQGFNKVAHFVCDYGPAGNYPTKPYKAGRPCSGCSNDQCVDNLCVNAEREKLISYANWYPDWDTEPQPPQPRPPQSPAPRPPAPRPPAPRPPAPRPPAPQPPAPRPPAQTPPAGQPHSSCDHYCVSVLILRPLFLVLSTVGVLFARRWFPHMFIYVQ", 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The reference sequence was derived from JAENSK010000012.1. On Oct 29, 2021 this sequence version replaced XP_040522140.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383911" } ] }, { "annotation": "BRAF alternative splicing is differentially regulated in avian, rodent and primates. Exon 9b is present in vertebrates but exon 8b is present only in eutherians. 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"RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YK46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN5-1", "url": 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"MAALSSGSSAEGASLFNGDMEPEPPPPVLGACYAGSGGGDPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK", "length": 807, "header": "tr|A0A8V0YMN5-1|A0A8V0YMN5_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK46/entry", "sequence": { "sequence": "MYAGDMVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH", "length": 726, "header": "tr|A0A8V0YK46-1|A0A8V0YMN5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "locus": { "chromosome": "1", "start_pos": 57035498, "end_pos": 56977774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032420.1", "url": "https://www.ensembl.org/id/ENSGALT00010032420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019183.1", "url": "https://www.ensembl.org/id/ENSGALP00010019183.1" } ] } }, { "isoform_ac": "A0A8V0YKS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS7/entry", "sequence": { "sequence": "MCSSNTGCRALLSTVGTEVSAIWHISYVKSVLEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH", "length": 753, "header": "tr|A0A8V0YKS7-1|A0A8V0YMN5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "locus": { "chromosome": "1", "start_pos": 57046628, "end_pos": 56977774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032426.1", "url": "https://www.ensembl.org/id/ENSGALT00010032426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019186.1", "url": "https://www.ensembl.org/id/ENSGALP00010019186.1" } ] } }, { "isoform_ac": "A0A8V0YMN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5/entry", "sequence": { "sequence": "MAALSSGSSAEGASLFNGDMEPEPPPPVLGACYAGSGGGDPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK", "length": 807, "header": "tr|A0A8V0YMN5-1|A0A8V0YMN5_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "locus": { "chromosome": "1", "start_pos": 57047458, "end_pos": 56972601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032437.1", "url": "https://www.ensembl.org/id/ENSGALT00010032437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019192.1", "url": "https://www.ensembl.org/id/ENSGALP00010019192.1" } ] } }, { "isoform_ac": "A0A8V0YSM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM4/entry", "sequence": { "sequence": "MAALSSGSSAEGASLFNGDMEPEPPPPVLGACYAGSGGGDPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSISYYLFANDYIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH", "length": 730, "header": "tr|A0A8V0YSM4-1|A0A8V0YMN5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "locus": { "chromosome": "1", "start_pos": 57047458, "end_pos": 56977774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032433.1", "url": "https://www.ensembl.org/id/ENSGALT00010032433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019190.1", "url": "https://www.ensembl.org/id/ENSGALP00010019190.1" } ] } }, { "isoform_ac": "A0A8V0YSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSN1/entry", "sequence": { "sequence": "MAALSSGSSAEGASLFNGDMEPEPPPPVLGACYAGSGGGDPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTDTVASSSSSSLSVAPSSLSVYQNPTDMSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPISQEETTLGETTPASGSYPSVPPSDSVGPPILPSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGVRGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYEGK", "length": 763, "header": "tr|A0A8V0YSN1-1|A0A8V0YMN5_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=BRAF PE=3 SV=1 CANONICAL=A0A8V0YMN5-1" }, "locus": { "chromosome": "1", "start_pos": 57047458, "end_pos": 56966924, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032441.1", "url": "https://www.ensembl.org/id/ENSGALT00010032441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019195.1", "url": "https://www.ensembl.org/id/ENSGALP00010019195.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.", "journal": "The EMBO journal", "date": "2002-11-01", "authors": "Brummer Tilman, Shaw Peter E, Reth Michael, Misawa Yukiko", "evidence": [ { "database": "RefSeq", "id": "NP_001383911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383911" } ], "reference": [ { "type": "PubMed", "id": "12411479", "url": "https://glygen.org/publication/PubMed/12411479" } ] }, { "title": "Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein.", "journal": "Oncogene", "date": "2006", "authors": "Brummer T, Martin P, Herzog S, Misawa Y, Daly RJ, Reth M", "evidence": [ { "database": "RefSeq", "id": "NP_001383911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383911" } ], "reference": [ { "type": "PubMed", "id": "16702958", "url": "https://glygen.org/publication/PubMed/16702958" } ] }, { "title": "B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse.", "journal": "PloS one", "date": "2010-12-22", "authors": "Valluet Agathe, Hmitou Isabelle, Davis Sabrina, Druillennec Sabine, Larcher Magalie, Laroche Serge, Eych\u00e8ne Alain", "evidence": [ { "database": "RefSeq", "id": "NP_001383911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383911" } ], "reference": [ { "type": "PubMed", "id": "21203559", "url": "https://glygen.org/publication/PubMed/21203559" } ] } ], "pathway": [ { "id": "R-GGA-1295596", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1295596", "resource": "Reactome", "description": "Spry regulation of FGF signaling" }, { "id": "R-GGA-170968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170968", "resource": "Reactome", "description": "Frs2-mediated activation" }, { "id": "R-GGA-5673000", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "resource": "Reactome", "description": "RAF activation" }, { "id": "R-GGA-5674135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "resource": "Reactome", "description": "MAP2K and MAPK activation" }, { "id": "R-GGA-5674499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674499", "resource": "Reactome", "description": "Negative feedback regulation of MAPK pathway" }, { "id": "R-GGA-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN5", "url": 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"A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-1295604", "name": "B-RAF dissociates from S110/S120 p-SPRY2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-1295604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1295604" } ] }, { "id": "R-GGA-1295634", "name": "SPRY2 is serine phosphorylated in response to MAPK activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A4Q4-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-1295634", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1295634" } ] }, { "id": "R-GGA-5672950", "name": "Activator\" RAF:YWHAB dimer binds RAS:GTP\"", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672950", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672950" } ] }, { "id": "R-GGA-5672951", "name": "Inactive RAFs bind YWHAB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672951", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672951" } ] }, { "id": "R-GGA-5672960", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672960", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672960" } ] }, { "id": "R-GGA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0ZZ54-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672966" } ] }, { "id": "R-GGA-5672969", "name": "Phosphorylation of RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0YNY4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672969" } ] }, { "id": "R-GGA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672973" } ] }, { "id": "R-GGA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672978" } ] }, { "id": "R-GGA-5674140", "name": "PAQR3 binds inactive RAFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P05625-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5674140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674140" } ] }, { "id": "R-GGA-5675198", "name": "Activated MAPKs phosphorylate BRAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-GGA-5672679" ], "output_participant_list": [ "R-GGA-5675199" ], "enzyme_list": [ "A0A8V1A4Q4-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5675198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675198" } ] }, { "id": "R-GGA-5675417", "name": "PEBP1 binds activated RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5675417", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675417" } ] }, { "id": "R-GGA-9610163", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NSA8-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9610163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9610163" } ] }, { "id": "R-GGA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9653108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9653108" } ] }, { "id": "R-GGA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657599" } ] }, { "id": "R-GGA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657603" } ] }, { "id": "R-GGA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657606" } ] }, { "id": "R-GGA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657608" } ] }, { "id": "R-GGA-9658445", "name": "MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZYK3-1", "P05625-1", "P62207-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9658445", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9658445" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-5672679", "participant_name": "phospho-p-S446,T599,S602,S729 BRAF [plasma membrane]", "crossref": [ { "id": "A0A8V0YMN5", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010013466", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010019192", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032437", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5675199", "participant_name": "phospho-hyperphosphorylated BRAF [plasma membrane]", "crossref": [ { "id": "ENSGALP00010019192", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YMN5", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010013466", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032437", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { 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{ "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } 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"activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": 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[ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZ54", "gene_name": "BRAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMN9-1", "uniprot_ac": "A0A8V0YMN9", "uniprot_id": "A0A8V0YMN9_CHICK", "mass": { "chemical_mass": 71710.0, "monoisotopic_mass": 71710.0 }, "refseq": {}, "gene_names": [ { "name": "ZDHHC17", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZDHHC17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9", "locus": { "chromosome": "1", "start_pos": 38327454, "end_pos": 38246786, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013476", "url": "https://www.ensembl.org/id/ENSGALG00010013476" } ] } } ], "crossref": [ { "id": "A0A8V0YMN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FWVGFRY", "url": "https://omabrowser.org/oma/group/FWVGFRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK55", "url": "https://www.orthodb.org/?gene=A0A8V0YK55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKT2", "url": "https://www.orthodb.org/?gene=A0A8V0YKT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMN9", "url": "https://www.orthodb.org/?gene=A0A8V0YMN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YK55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAVSCIQGLWCFSPALHSASHQEIKPQSHYNHGYSESLGRKSHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESPLDLAKQRKNVWMINHLQEARQAKGYDSPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWAMVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFFFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGFHCETSYAKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCIRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQTSGSGYQLV", "length": 624, "header": "tr|A0A8V0YMN9-1|A0A8V0YMN9_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC17 PE=3 SV=1 CANONICAL=A0A8V0YMN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK55/entry", "sequence": { "sequence": "MAAPLDEYEKEAGCVPILHPEEIKPQSHYNHGYSESLGRKSHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESPLDLAKQRKNVWMINHLQEARQAKGYDSPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWAMVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFFFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGFHCETSYAKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCIRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQTSGSGYQLV", "length": 622, "header": "tr|A0A8V0YK55-1|A0A8V0YMN9_CHICK Computationally mapped isoform of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC17 PE=3 SV=1 CANONICAL=A0A8V0YMN9-1" }, "locus": { "chromosome": "1", "start_pos": 38324445, "end_pos": 38261325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032438.1", "url": "https://www.ensembl.org/id/ENSGALT00010032438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019193.1", "url": "https://www.ensembl.org/id/ENSGALP00010019193.1" } ] } }, { "isoform_ac": "A0A8V0YKT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT2/entry", "sequence": { "sequence": "MAAPLDEYEKEAGCVPILHPEEIKPQSHYNHGYSESLGRKSHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKAVPRCLMAL", "length": 256, "header": "tr|A0A8V0YKT2-1|A0A8V0YMN9_CHICK Computationally mapped isoform of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC17 PE=3 SV=1 CANONICAL=A0A8V0YMN9-1" }, "locus": { "chromosome": "1", "start_pos": 38299491, "end_pos": 38261325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032434.1", "url": "https://www.ensembl.org/id/ENSGALT00010032434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019191.1", "url": "https://www.ensembl.org/id/ENSGALP00010019191.1" } ] } }, { "isoform_ac": "A0A8V0YMN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9/entry", "sequence": { "sequence": "MTAVSCIQGLWCFSPALHSASHQEIKPQSHYNHGYSESLGRKSHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESPLDLAKQRKNVWMINHLQEARQAKGYDSPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWAMVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFFFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGFHCETSYAKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCIRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQTSGSGYQLV", "length": 624, "header": "tr|A0A8V0YMN9-1|A0A8V0YMN9_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC17 PE=3 SV=1 CANONICAL=A0A8V0YMN9-1" }, "locus": { "chromosome": "1", "start_pos": 38324445, "end_pos": 38246955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032443.1", "url": "https://www.ensembl.org/id/ENSGALT00010032443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019197.1", "url": "https://www.ensembl.org/id/ENSGALP00010019197.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A5WVX9-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "zdhhc17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADALVGYEKEAGCVPILHPEEIKPQSHYNHGYNESRKSHVDDYSTWDIVKATQYGIFERCRELVEAGYDVRQPDKENVTLLHWAAINNRVDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCVHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEANANVDAQNIKGETPLDLAKQRKNVWMINHLQEARQAKGYDSPSYLKRLKMDKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGVMYAVMWLVVQFLSKSFFDHSMHSALPLGIYLATKFWMYITWFYWFWNDLPFVTIHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQKKKTIVELAETGSLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWRIHCATSYTKDGFWIYITQIATCSPWMFWMFLNSVFHFMWVAVLIMCQLYQIAVLGITTNERMNARRYKHFKVTATSIESPFNHGCMRNLIDFFELRCCGLLRPVPIDWTSQYTIEYDQTSGSGYQLV", "length": 620 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BJK1-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQREEGFNTKMADGPDEYESEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSIALFYNFGKSWKSDPGIIKATEEQKKKIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETSYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 611 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PTT0-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "Zdhhc17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADGPDEYDTETGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHVDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLSFLSIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQITCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 622 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39010-1", "protein_name": "Palmitoyltransferase AKR1", "gene_name": "AKR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVNELENVPRASTLTNEEQTVDPSNNDSQEDISLGDSNEITSLASLKAIRSGNEEESGNEQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREALTHSGFDYHGYPIKKWFKKSQHAKLVTFITPFLFLGIAFALFSHINPLFVIIVLFLLAIATNKGLNKFVLPSYGRMGVHNVTLLRSPLLSGVFFGTLLWVTIVWFFKVMPRTFSDEQYTNILMLVILVSVFYLFGQLVIMDPGCLPEETDHENVRQTISNLLEIGKFDTKNFCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDVGLKNHKAFIFFITLMESGIFTFLALCLEYFDELEDAHEDTSQKNGKCFILGASDLCSGLIYDRFVFLILLWALLQSIWVASLIFVQAFQICKGMTNTEFNVLMKESKSIGPDGLSFNENFNTTPEGFAPSIDPGEESNDTVLAPVPGSTIRKPRTCFGVCYAVTGMDQWLAVIKETIGIKDSTGHNVYSITSRIPTNYGWKRNVKDFWLTSDINAPLWRRILYPPSGSKALLNGIEVDYFKLYKLPNKDVEQGNDMV", "length": 764 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3EC11-1", "protein_name": "Probable protein S-acyltransferase 23", "gene_name": "PAT23", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSEIEVVPLDSNSHQSPTESPTITDVFSASAYGDLHQLKHFVEHNGSSVSLPDDNGFYALQWAALNNSLHVAQYIIQHGGDVNSADNIQQTPLHWAAVKGSIDVADLLLQHGARIEAVDVNGFRAVHVASQYGQTAFVNHIIVDYAADYNALDIEGRSPLHWAAYNGFTETVRLLLFRDACQNRQDNTGCTPLHWAVIKENVEACTLLVHAGTKEELILKDNTGSTPLKLASDKGHRQLALFLSKAMRTRKNSFVDKIFCGKLGETSYAPMLFSLIVILMVLFITSIVSASNLPKITAMVGLWACFGLSCGVYALITFYRVSRKDPGYVKRTGEANSQHTANDPLIDINFKNPSWKGNWSQLCPTCKIIRPVRSKHCPTCKRCVEQFDHHCPWISNCVGKKNKRYFLVFVIMGALTSFVGGTTAVQRLWRGIPQVHHGESWIKHIVIEHPDAAVFLFFDLLIFIATMTLTISQSYMIARNITTNELWNAKRFSYLRGPDGRFYNPYNHGLRRNCTDFLVHGYTRDDEVVPSSIL", "length": 536 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q80TN5-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "Zdhhc17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREEGFNTKMADGPDEYETETGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFLWVAVLLMCQLYQITCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 632 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IUH5-1", "protein_name": "Palmitoyltransferase ZDHHC17", "gene_name": "ZDHHC17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV", "length": 632 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUW9-1", "protein_name": "Palmitoyltransferase Hip14", "gene_name": "Hip14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYQSACQAATTGSCVPGTGQQPDNERQSALIAQQPPTAPVEPDYSGFDIVKATQYGAIARVRELVESGWDVNQPDSETVTLLHWAAINNRRDIIRYFLEKGATVDAVGGELNATPLHWATRQGHLGAVVLLMAAGADPRIRDAEGCSCIHIAAQFAHTALVAYFIAKGVDPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANPAMVDYTHGNTALHWAILARNATAISTLVLKSKASLDVPNLRGETPLSMLESQTGAIWIGAKVMDRVKEAALTSQQRRSLLSKLRHDKRLRWWSMVACPFTAFYLAGIVFTVNTLYIIKFFLLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLWVCFLKSWKGDPGIIRPTREQRFKTIIELSERGGIGFEPASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYGGSKYYVNQCNVRFDDFLGAMRAIGNCDAWVGWVMGNALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRHFQAKGGHSPFTRGPIQNLVDFLECSCFGLVQPKRVDWMNYYDYDAQTHQTIEKEPLLSVDCPDGMAGDHQYV", "length": 637 }, "evidence": [ { "id": "A0A8V0YMN9", "url": "https://omabrowser.org/oma/group/A0A8V0YMN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "Golgi-associated vesicle membrane", "id": "GO:0030660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030660", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "postsynaptic Golgi apparatus", "id": "GO:0150051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150051", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "perforant pathway to dendrate granule cell synapse", "id": "GO:0140240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "regulation of programmed cell death", "id": "GO:0043067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043067", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "regulation of neurotrophin TRK receptor signaling pathway", "id": "GO:0051386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" }, { "name": "regulation of modification of synapse structure, modulating synaptic transmission", "id": "GO:0098987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUB9-1", "A0A1D5NVK1-1", "A0A1D5PDT8-1", "A0A1D5PVV6-1", "A0A8V0XHB8-1", "A0A8V0XMA1-1", "A0A8V0XVP6-1", "A0A8V0YMW4-1", "A0A8V0YMN9-1", "A0A8V0YME7-1", "A0A8V0YPS8-1", "A0A8V0ZFK7-1", "A0A8V1ACZ6-1", "A0A8V0Z649-1", "A0A8V0ZZH0-1", "A0A8V0ZI56-1", "A0A8V1A9I9-1", "A0A8V1AH42-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVK1", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] } ] }, { "uniprot_ac": "A0A1D5PDT8", "gene_name": "ZDHHC16", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5PDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5PDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDT8" } ] } ] }, { "uniprot_ac": "A0A1D5PVV6", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5PVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVV6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5PVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVV6" } ] } ] }, { "uniprot_ac": "A0A8V0XHB8", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHB8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHB8" } ] } ] }, { "uniprot_ac": "A0A8V0XMA1", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XMA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XMA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA1" } ] } ] }, { "uniprot_ac": "A0A8V0XVP6", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVP6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVP6" } ] } ] }, { "uniprot_ac": "A0A8V0YME7", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7" } ] } ] }, { "uniprot_ac": "A0A8V0YMN9", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ] } ] }, { "uniprot_ac": "A0A8V0YMW4", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ] } ] }, { "uniprot_ac": "A0A8V0YPS8", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ] } ] }, { "uniprot_ac": "A0A8V0YUB9", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YUB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YUB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB9" } ] } ] }, { "uniprot_ac": "A0A8V0Z649", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0Z649", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z649" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0Z649", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z649" } ] } ] }, { "uniprot_ac": "A0A8V0ZFK7", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZFK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK7" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZFK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK7" } ] } ] }, { "uniprot_ac": "A0A8V0ZI56", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI56" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI56" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH0", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZZH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZZH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH0" } ] } ] }, { "uniprot_ac": "A0A8V1A9I9", "gene_name": "LOC100858962", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1A9I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1A9I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I9" } ] } ] }, { "uniprot_ac": "A0A8V1ACZ6", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1ACZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1ACZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ6" } ] } ] }, { "uniprot_ac": "A0A8V1AH42", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1AH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH42" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1AH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH42" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 430, "end_pos": 561, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.225", "ec_name": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "2.3.1.225", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225" }, { "id": "2.3.1.225", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.225" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMJ9-1", "uniprot_ac": "A0A8V0YMJ9", "uniprot_id": "A0A8V0YMJ9_CHICK", "mass": { "chemical_mass": 39782.0, "monoisotopic_mass": 39782.0 }, "refseq": {}, "gene_names": [ { "name": "CD74", "type": "recommended", "evidence": [ { "id": "A0A8V0YMJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9" } ] } ], "protein_names": [ { "name": "CD74 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0YMJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9", "locus": { "chromosome": "13", "start_pos": 12755985, "end_pos": 12748661, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013450", "url": "https://www.ensembl.org/id/ENSGALG00010013450" } ] } } ], "crossref": [ { "id": "A0A8V0YMJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP1", "url": "https://www.orthodb.org/?gene=A0A8V0YKP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMJ9", "url": "https://www.orthodb.org/?gene=A0A8V0YMJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSK3", "url": "https://www.orthodb.org/?gene=A0A8V0YSK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWSGAVCPVTGDSSRCFPCHRQHTAAQQQRCSGRDSASTVDRRPSALSSAWQQVMHGQQPMGLFFCPSPRGWQGGGCLVGVFPAAVCGALISPSGSSGATMAEEQRDLISSDGSSGVLPIGNSERSSLGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQRKMPIGTQPANKMSMSTMNMPMAMKVLPLAPSVGDMPMEAMKPRSNKTEDQIRHLLLKSDPRKTFPDLKDDMLGNLKRLKKTMSAMDWQDFETWMHKWLLFEMAKGPKMEEQNTIPAEKVQTKCQAEASFGGVHPGRFRPECDENGDYLPKQCYASTGYCWCCYKNGTRIEGTATRGQLDCSAK", "length": 363, "header": "tr|A0A8V0YMJ9-1|A0A8V0YMJ9_CHICK Isoform 1 of CD74 molecule OS=Gallus gallus OX=9031 GN=CD74 PE=1 SV=1 CANONICAL=A0A8V0YMJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP1/entry", "sequence": { "sequence": "MAEEQRDLISSDGSSGVLPIGNSERSSLGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQRKMPIGTQPANKMSMSTMNMPMAMKVLPLAPSVGDMPMEAMKPRSNKTEDQIRHLLLVSSPTHLTDSADRSSDFETWMHKWLLFEMAKGPKMEEQNTIPAEKVQTKCQAEASFGGVHPGRFRPECDENGDYLPKQCYASTGYCWCCYKNGTRIEGTATRGQLDCSAPAPTQPPSAEPEEVIFSGVDMVKGKKPWG", "length": 273, "header": "tr|A0A8V0YKP1-1|A0A8V0YMJ9_CHICK Computationally mapped isoform of CD74 molecule OS=Gallus gallus OX=9031 GN=CD74 PE=1 SV=1 CANONICAL=A0A8V0YMJ9-1" }, "locus": { "chromosome": "13", "start_pos": 12753468, "end_pos": 12750560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032381.1", "url": "https://www.ensembl.org/id/ENSGALT00010032381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019150.1", "url": "https://www.ensembl.org/id/ENSGALP00010019150.1" } ] } }, { "isoform_ac": "A0A8V0YKQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ1/entry", "sequence": { "sequence": "MEWSGAVCPVTGDSSRCFPCHRQHTAAQQQRCSGRDSASTVDRRPSALSSAWQQVMHGQQPMGLFFCPSPRGWQGGGCLVGVFPAAVCGALISPSGSSGATMAEEQRDLISSDGSSGVLPIGNSERSSLGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQRKMPIGTQPANKMSMSTMNMPMAMKVLPLAPSVGDMPMEAMKPRSNKTEDQIRHLLLKSDPRKTFPDLKDDMLGNLKRLKKTMSAMDWQDFETWMHKWLLFEMAKGPKMEEQNTIPAEKAPAPTQPPSAEPEEVIFSGVDMVKAK", "length": 324, "header": "tr|A0A8V0YKQ1-1|A0A8V0YMJ9_CHICK Computationally mapped isoform of CD74 molecule OS=Gallus gallus OX=9031 GN=CD74 PE=1 SV=1 CANONICAL=A0A8V0YMJ9-1" }, "locus": { "chromosome": "13", "start_pos": 12753614, "end_pos": 12750257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032392.1", "url": "https://www.ensembl.org/id/ENSGALT00010032392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019160.1", "url": "https://www.ensembl.org/id/ENSGALP00010019160.1" } ] } }, { "isoform_ac": "A0A8V0YKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ6/entry", "sequence": { "sequence": "MAEEQRDLISSDGSSGVLPIGNSERSSLGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQRKMPIGTQPANKMSMSTMNMPMAMKVLPLAPSVGDMPMEAMKPRSNKTEDQIRHLLLKSDPRKTFPDLKDDMLGNLKRLKKTMSAMDWQDFETWMHKWLLFEMAKGPKMEEQNTIPAEKAVGMGCNSLQS", "length": 208, "header": "tr|A0A8V0YKQ6-1|A0A8V0YMJ9_CHICK Computationally mapped isoform of CD74 molecule OS=Gallus gallus OX=9031 GN=CD74 PE=1 SV=1 CANONICAL=A0A8V0YMJ9-1" }, "locus": { "chromosome": "13", 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"start_pos": 12753614, "end_pos": 12750257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032388.1", "url": "https://www.ensembl.org/id/ENSGALT00010032388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019156.1", "url": "https://www.ensembl.org/id/ENSGALP00010019156.1" } ] } }, { "isoform_ac": "A0A8V0YSK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSK3/entry", "sequence": { "sequence": "MHGQQPMGLFFCPSPRGWQGGGCLVGVFPAAVCGALISPSGSSGATMAEEQRDLISSDGSSGVLPIGNSERSSLGRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQRKMPIGTQPANKMSMSTMNMPMAMKVLPLAPSVGDMPMEAMKPRSNKTEDQIRHLLLKSDPRKTFPDLKDDMLGNLKRLKKTMSAMDWQDFETWMHKWLLFEMAKGPKMEEQNTIPAEKAPAPTQPPSAEPEEVIFSGVDMVKAK", "length": 269, "header": "tr|A0A8V0YSK3-1|A0A8V0YMJ9_CHICK Computationally mapped isoform of CD74 molecule OS=Gallus gallus OX=9031 GN=CD74 PE=1 SV=1 CANONICAL=A0A8V0YMJ9-1" }, "locus": { "chromosome": "13", "start_pos": 12753614, "end_pos": 12750422, "strand": "-", "evidence": [ 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN62-1", "uniprot_ac": "A0A8V0YN62", "uniprot_id": "A0A8V0YN62_CHICK", "mass": { "chemical_mass": 170035.0, "monoisotopic_mass": 170035.0 }, "refseq": {}, "gene_names": [ { "name": "PIK3C2G", "type": "recommended", "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma", "type": "synonym", "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIK3C2G", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62", "locus": { "chromosome": "1", "start_pos": 64239132, "end_pos": 63958633, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013617", "url": "https://www.ensembl.org/id/ENSGALG00010013617" } ] } } ], "crossref": [ { "id": "cd04012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05177", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05177", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP5", "url": "https://www.orthodb.org/?gene=A0A8V0YKP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB4", "url": "https://www.orthodb.org/?gene=A0A8V0YLB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLC7", "url": "https://www.orthodb.org/?gene=A0A8V0YLC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN62", "url": "https://www.orthodb.org/?gene=A0A8V0YN62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10048:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10048:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00792", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00792", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1660514", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12709", "url": "https://www.rhea-db.org/rhea/12709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18373", "url": "https://www.rhea-db.org/rhea/18373", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYFEKVPLSGNEFHEGHAGDQASYLAYHSGSYGKVYLGFDQIVDEVNNEFFFYGSSHLHHPEEHFFSSDIFSLNVPEQQLCSQPSVACGELHSENFVPHWQQGTVSPYIGFKSSLLSDDGNFSLVDSYPYNQEREIYRWNSSTPVPNVLNSNVERGYAYWNFQIGFDNVDAQCPVFLDKYPFGQRRDESGNGEACLTNTSRRFSIGSTWPKSPGHDREVTGWSIQLIKANQGSNENAVSFCNTVEKIRNTYPACDLKTNTGKIWSVATKFPDHILGKIRLRISIWTDSSPSPLLLTQHAGCITHDLIVEILRCTNQYPVHEECLLSVCGSDEFLQNNHSLGNHESLRKATTDIHLHLHSTTNLKQSLARVHEDDQGRFSVNELLEYTCAWRLTRQNLFAALRKYRGQVEHLLQNEPYKVDYVIEVAKAICSVLCFVETREITSAVKKLHAVPLVKTQDSLQHVEAQATLVAVCSERQTALTEAAVTELSMAISHLIHVYSSSFDTDFQVANIPRSPSRADISLDSQLSFTVYAAHNIPESWVNRYKLFSFSCLLTYAGKTICQVKICKNIPVRKSFFFLTDWNEKINFPLRIKALPRETMLTIKLLGLNSASKTTEMLAWTCCPLYQKEQLIHGTVLLSMKLYSMLPAAMITPAMCSTDAPTSVTLQIEFPETDLEFINPEPEERRDDLAEPTEECMKHIARLSQAHSLLLLSEQQKRILWFYRYYCNNQNCSLPLVLGSAPSWDRTTVSEMYSVMRKWRFSNPVEALGLLAFSFPDKDIRRTAVQQIENLSNDELLEYLPQLVQVLKFEWSLEGPLVKLLLNRSLQSIQVAHQLYWLLKNAQNEVHFKVWYRKLLAALQFTAGKALNNEFSKEEKLIRILEDTAEKVKVASDTKRKEVLKMELNRLQQFFQEVKVCRLPLNPALVVQGIEADSCSYFTSNAFPLKIRFINANAPSGNINIIFKIGDDLRQDMLVLQIVRVMDNIWLQEGLDMQMIIYRCLSTGKGQGLVQMVPDATTLAKIHRESGLIGPLKENTIRKWFRHHHRLESSYQEAIRNFFHSCAGWCVVTFILGVCDRHNDNIMLTNSGHMFHIDFGRFLGHAQTFGSIRRDRAPFIFTSEMEYFITEGGKSPQRFQEFVELCCRAYNIVRKHSQLLLNLLEMMLHAGLPELNSIQDLKYVYDNLRPQDSDLQATSYFTRKIKESLECFPVKLNNLIHTLAHMSLAGSAKFPSQETVPQEWMMLNAEKSIARATILGFNKKSDYLYLVQVVQTCSVVTFVEKSFDQFSELHSNLQKQFPSHALPEFPHSWHIPFTDLEHKRVKDLNLYLKQLLSGSRKLANNELVLSFFLNWSKHTLAEAASSVTSGPQSTDGTPGVQLVISYEGTHLTVMLKHMRNIRLPDGSAPSAHAEFYLLPDPGEVNRRKTRTVPKTTNPTYNEIVVYNKVMQLEGHILKLVVKSKGTFVGAVNIQLSRVQLNEEKWYPLGNSVI", "length": 1490, "header": "tr|A0A8V0YN62-1|A0A8V0YN62_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma OS=Gallus gallus OX=9031 GN=PIK3C2G PE=3 SV=1 CANONICAL=A0A8V0YN62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP5/entry", "sequence": { "sequence": "MAYFEKVPLSGNEFHEGHAGDQASYLAYHSGSYGKVYLGFDQIVDEVNNEFFFYGSSHLHHPEEHFFSSDIFSLNVPEQQLCSQPSVACGELHSENFVPHWQQGTVSPYIGFKSSLLSDDGNFSLVDSYPYNQEREIYRWNSSTPVPNVLNSNVERGYAYWNFQIGFDNVDAQCPVFLDKYPFGQRRDESGNGEACLTNTSRRFSIGSTWPKSPGHDREVTGWSIQLIKANQGSNENAVSFCNTVEKIRNTYPACDLKTNTGKIWSVATKFPDHILGKIRLRISIWTDSSPSPLLLTQHAGCITHDLIVEILRCTNQYPVHEECLLSVCGSDEFLQNNHSLGNHESLRKATTDIHLHLHSTTNLKQSLARVHEDDQGRFSVNELLEYTCAWRLTRQNLFAALRKYRGQVEHLLQNEPYKVDYVIEVAKAICSVLCFVETREITSAVKKLHAVPLVKTQDSLQHVEAQALTEAAVTELSMAISHLIHVYSSSFDTDFQVANIPRSPSRADISLDSQLSFTVYAAHNIPESWVNRYKLFSFSCLLTYAGKTICQVKICKNIPVRKSFFFLTDWNEKINFPLRIKALPRETMLTIKLLGLNSASKTTEMLAWTCCPLYQKEQLIHGTVLLSMKLYSMLPAAMITPAMCSTDAPTSVTLQIEFPETDLEFINPEPEERRDDLAEPTEECMKHIARLSQAHSLLLLSEQQKRILWFYRYYCNNQNCSLPLVLGSAPSWDRTTVSEMYSVMRKWRFSNPVEALGLLAFSFPDKDIRRTAVQQIENLSNDELLEYLPQLVQVLKFEWSLEGPLVKLLLNRSLQSIQVAHQLYWLLKNAQNEVHFKVWYRKLLAALQFTAGKALNNEFSKEEKLIRILEDTAEKVKVASDTKRKEVLKMELNRLQQFFQEVKVCRLPLNPALVVQGIEADSCSYFTSNAFPLKIRFINANAPSGNINIIFKIGDDLRQDMLVLQIVRVMDNIWLQEGLDMQMIIYRCLSTGKGQGLVQMVPDATTLAKIHRESGLIGPLKENTIRKWFRHHHRLESSYQEAIRNFFHSCAGWCVVTFILGVCDRHNDNIMLTNSGHMFHIDFGRFLGHAQTFGSIRRDRAPFIFTSEMEYFITEGGKSPQRFQEFVELCCRAYNIVRKHSQLLLNLLEMMLHAGLPELNSIQDLKYVYDNLRPQDSDLQATSYFTRKIKESLECFPVKLNNLIHTLAHMSLAGSAKFPSQETVPQEWMMLNAEKSIARATILGFNKKSDYLYLVQVVQTCSVVTFVEKSFDQFSELHSNLQKQFPSHALPEFPHSWHIPFTDLEHKRVKDLNLYLKQLLSGSRKLANNELVLSFFLNWSKHTLAEAASSVTSGPQSTDGTPGVQLVISYEGTHLTVMLKHMRNI", "length": 1386, "header": "tr|A0A8V0YKP5-1|A0A8V0YN62_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma OS=Gallus gallus OX=9031 GN=PIK3C2G PE=3 SV=1 CANONICAL=A0A8V0YN62-1" }, "locus": { "chromosome": "1", "start_pos": 64215260, "end_pos": 64041193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032710.1", "url": "https://www.ensembl.org/id/ENSGALT00010032710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019380.1", "url": "https://www.ensembl.org/id/ENSGALP00010019380.1" } ] } }, { "isoform_ac": "A0A8V0YLB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB4/entry", "sequence": { "sequence": "MAYFEKVPLSGNEFHEGHAGDQASYLAYHSGSYGKVYLGFDQIVDEVNNEFFFYGSSHLHHPEEHFFSSDIFSLNVPEQQLCSQPSVACGELHSENFVPHWQQGTVSPYIGFKSSLLSDDGNFSLVDSYPYNQEREIYRWNSSTPVPNVLNSNVERGYAYWNFQIGFDNVDAQCPVFLDKYPFGQRRDESGNGEACLTNTSRRFSIGSTWPKSPGHDREVTGWSIQLIKANQGSNENAVSFCNTVEKIRNTYPACDLKTNTGKIWSVATKFPDHILGKIRLRISIWTDSSPSPLLLTQHAGCITHDLIVEILRCTNQYPVHEECLLSVCGSDEFLQNNHSLGNHESLRKATTDIHLHLHSTTNLKQSLARVHEDDQGRFSVNELLEYTCAWRLTRQNLFAALRKYRGQVEHLLQNEPYKVDYVIEVAKAICSVLCFVETREITSAVKKLHAVPLVKTQDSLQHVEAQALTEAAVTELSMAISHLIHVYSSSFDTDFQVANIPRSPSRADISLDSQLSFTVYAAHNIPESWVNRYKLFSFSCLLTYAGKTICQVKICKNIPVRKSFFFLTDWNEKINFPLRIKALPRETMLTIKLLGLNSASKTTEMLAWTCCPLYQKEQLIHGTVLLSMKLYSMLPAAMITPAMCSTDAPTSVTLQIEFPETDLEFINPEPEERRDDLAEPTEECMKHIARLSQAHSLLLLSEQQKRILWFYRYYCNNQNCSLPLVLGSAPSWDRTTVSEMYSVMRKWRFSNPVEALGLLAFSFPDKDIRRTAVQQIENLSNDELLEYLPQLVQVLKFEWSLEGPLVKLLLNRSLQSIQVAHQLYWLLKNAQNEVHFKVWYRKLLAALQFTAGKALNNEFSKEEKLIRILEDTAEKVKVASDTKRKEVLKMELNRLQQFFQEVKVCRLPLNPALVVQGIEADSCSYFTSNAFPLKIRFINANAPSGNINIIFKIGDDLRQDMLVLQIVRVMDNIWLQEGLDMQMIIYRCLSTGKGQGLVQMVPDATTLAKIHRESGLIGPLKENTIRKWFRHHHRLESSYQEAIRNFFHSCAGWCVVTFILGVCDRHNDNIMLTNSGHMFHIDFGRFLGHAQTFGSIRRDRAPFIFTSEMEYFITEGGKSPQRFQEFVELCCRAYNIVRKHSQLLLNLLEMMLHAGLPELNSIQDLKYVYDNLRPQDSDLQATSYFTRKIKESLECFPVKLNNLIHTLAHMSLAGSAKFPSQETVPQEWMMLNAEKSIARATILGFNKKSDYLYLVQVVQTCSVVTFVEKSFDQFSELHSNLQKQFPSHALPEFPHSWHIPFTDLEHKRVKDLNLYLKQLLSGSRKLANNELVLSFFLNWSKHTLAEAASSVTSGPQSTDGTPGVQLVISYEGTHLTVMLKHMRNINWSTNREELSRGSSGELQEAMSPDAVMLISIAHCLEVKWEILHVLGARVRKEKAGRAPSTQAPPRWLCPKCTC", "length": 1459, "header": "tr|A0A8V0YLB4-1|A0A8V0YN62_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma OS=Gallus gallus OX=9031 GN=PIK3C2G PE=3 SV=1 CANONICAL=A0A8V0YN62-1" }, "locus": { "chromosome": "1", "start_pos": 64232798, "end_pos": 64041193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032724.1", "url": "https://www.ensembl.org/id/ENSGALT00010032724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019388.1", "url": "https://www.ensembl.org/id/ENSGALP00010019388.1" } ] } }, { "isoform_ac": "A0A8V0YLC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC7/entry", "sequence": { "sequence": 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"length": 1490, "header": "tr|A0A8V0YN62-1|A0A8V0YN62_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma OS=Gallus gallus OX=9031 GN=PIK3C2G PE=3 SV=1 CANONICAL=A0A8V0YN62-1" }, "locus": { "chromosome": "1", "start_pos": 64238385, "end_pos": 64041193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032733.1", "url": "https://www.ensembl.org/id/ENSGALT00010032733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019394.1", "url": "https://www.ensembl.org/id/ENSGALP00010019394.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1374, "start_aa": "Thr", "end_pos": 1374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1374", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-1660514", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "resource": "Reactome", "description": "Synthesis of PIPs at the Golgi membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-3-kinase activity", "id": "GO:0016303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016303", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 3-kinase activity", "id": "GO:0035005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate biosynthetic process", "id": "GO:0036092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "host-mediated perturbation of viral process", "id": "GO:0044788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1351, "end_pos": 1353, "annotation": 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{ "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "F1NHX1", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1NHX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHX1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1373, "end_pos": 1490, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS51547", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51547" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 PI3K-type", "eco_id": "ECO_0000259", "start_pos": 524, "end_pos": 672, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS51546", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51546" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PI3K-RBD", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 363, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS50290", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50290" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PI3K/PI4K catalytic", "eco_id": "ECO_0000259", "start_pos": 932, "end_pos": 1210, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS51545", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51545" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIK helical", "eco_id": "ECO_0000259", "start_pos": 687, "end_pos": 863, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN62" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 1244, "end_pos": 1356, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1374 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 1351, "end_pos": 1353 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 824, "end_pos": 826 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLG8-1", "uniprot_ac": "A0A8V0YLG8", "uniprot_id": "A0A8V0YLG8_CHICK", "mass": { "chemical_mass": 143919.0, "monoisotopic_mass": 143919.0 }, "refseq": {}, "gene_names": [ { "name": "SHROOM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8" } ] } ], "protein_names": [ { "name": "Shroom family member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHROOM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8", "locus": {} } ], "crossref": [ { "id": "416335", "url": "https://www.ncbi.nlm.nih.gov/gene/416335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416335", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMTENQL", "url": "https://omabrowser.org/oma/group/YMTENQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKX7", "url": "https://www.orthodb.org/?gene=A0A8V0YKX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLG8", "url": "https://www.orthodb.org/?gene=A0A8V0YLG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08688", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08688", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YKX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSENETERWPCRHGGRIGALVEPTAPSDSSHLSPLPPLGSTEHILHLPGRADSAYSSFSGGSNVPEHQPPSLYEADCCSAAEQVPYMDSEYVRGIYNLSAASSALRCLQPYQAPSQSIPGVSHSPALAECSSGTPSHGTLEQGLPPPAAPPPSPPMRLDSYRVTRHLESTKGRGRQNSGGLSECNAQSAPCMDSRPVGVSHGQMGPGSSEPAMAAARRRTEENGEWNPSQKPVRRSNPHVYSRPSSFIFQEYLKTDSMANVPKILSTYGSAHVHNVSEEVKPRPYTSAHSSPGAAGDARGDVELQSAVLEHSRWKGSPLCAQCPLRAELPPDMGQEVSEDICDLKCMENALLIKNASRKSSICTDKNGCYDSKGEIGSIVRELLLNPQGKIQKSLLSSSCDAVELEQPPSGKLDHGNKQCCDNTEQMAFLRPKEDSSSQPLNEGCANSSSPGLNGQLEQEQPPAPYQKCQPELQQELLRQALDDPAGEQITRQVTPMLYYLSGGRAANTTHHSRLTQCPEGVRSSPKGFATSSHTASAWSKEMQRESSQSRKVEHRQCCANGDPLNEAEDVALGGPASSTEESSKNDYREKLKVAQKKVLRETSFKRKDLQMSLPVRLRQKPSKRPSIEHLRSFSLSSAHEDSKSAPCSASCLESLEGFNTDAEIKRPQAGRIGGRKRATKEEKKLCYSEPEKLNQLADKEAQGSTEQDMARRRTSESRGRALSSSSISRTELKQIQHTALMEYMERKISQRPGSTQHAPPHKPALQMGPLHPKWPPGRSSNPGESRKTPSNGASCQVFSEEAAPDVFPPSSPVPPPNTGGGCGVVPAKPSLHPAAPDRSCSPECVSAQSVPLSGAAAQGQEVEHPSMQAADSRAVPPARPCGNHISTPSSHDPREDGCQNHEHRDSVVGSSVCQHSEELAASTSIPSPRKGSRDNAQVEKKSRSGSQTGNALTTCPELQPKTSSAAAVQGNAAILVLPAQPQQGDGGKASAWGVKKAAAHNGRDGVLQEGETELPQRRLWSPEDRCYEELTMDLIAKDSSLVDVLMPYPDRKTALDLMEGLFPVNISVLEMHRRKADVRRARENDRKSSGDVTEECPESELTAKQRSEDPTGKGNRALSGSGDDTKDLDDITCKKKLGCTPSQLELISSLRAKVRALEEDRELVLTEAKQCAERGEELEAAVRAACKPNELERYVMFIGDLEKVVSLLLCLSSRLARVQNAMRKIDGNTDAEEKQSLNERHKLLSRQREDAKDLKENLDRRERVVAGILAKYLTDQQLQAYRHFVQLKTSLLIEQKDLEEQIKFFKEQLENLEKSIPF", "length": 1321, "header": "tr|A0A8V0YLG8-1|A0A8V0YLG8_CHICK Isoform 1 of Shroom family member 1 OS=Gallus gallus OX=9031 GN=SHROOM1 PE=1 SV=1 CANONICAL=A0A8V0YLG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX7/entry", "sequence": { "sequence": "MAVSENETERWPCRHGGRIGALVEPTAPSDSSHLSPLPPLGSTEHILHLPGRADSAYSSFSGGSNVPEHQPPSLYEADCCSAAEQVPYMDSEYVRGIYNLSAASSALRCLQPYQAPSQSIPGVSHSPALAECSSGTPSHGTLEQGLPPPAAPPPSPPMRLDSYRVTRHLESTKGRGRQNSGGLSECNAQSAPCMDSRPVGVSHGQMGPGSSEPAMAAARRRTEENGEWNPSQKPVRRSNPHVYSRPSSFIFQEYLKTDSMANVPKILSTYGSAHVHNVSEEVKPRPYTSAHSSPGAAGDARGDVELQSAVLEHSRWKGSPLCAQCPLRAELPPDMGQEVSEDICDLKCMENALLIKNASRKSSICTDKNGCYDSKGEIGSIVRELLLNPQGKIQKSLLSSSCDAVELEQPPSGKLDHGNKQCCDNTEQMAFLRPKEDSSSQPLNEGCANSSSPGLNGQLEQEQPPAPYQKCQPELQQELLRQALDDPAGEQITRQVTPMLYYLSGGRAANTTHHSRLTQCPEGVRSSPKGFATSSHTASAWSKEMQRESSQSRKVEHRQCCANGDPLNEAEDVALGGPASSTEESSKNDYREKLKVAQKKVLRETSFKRKDLQMSLPVRLRQKPSKRPSIEHLRSFSLSSAHEDSKSAPCSASCLESLEGFNTDAEIKRPQAGRIGGRKRATKEEKKLCYSEPEKLNQLADKEAQGSTEQDMARRRTSESRGRALSSSSISRTELKQIQHTALMEYMERKISQRPGSTQHAPPHKPALQMGPLHPKWPPGRSSNPGESRKTPSNGASCQVFSEEAAPDVFPPSSPVPPPNTGGGCGVVPAKPSLHPAAPDRSCSPECVSAQSVPLSGAAAQGQEVEHPSMQAADSRAVPPARPCGNHISTPSSHDPREDGCQNHEHRDSVVGSSVCQHSEELAASTSIPSPRKGSRDNAQVEKKSRSGSQTGNALTTCPELQPKTSSAAAVQGNAAILVLPAQPQQGDGGKASAWGVKKAAAHNGRDGVLQEGETELPQRRLWSPEDRCYEELTMDLIAKDSSLVDVLMPYPDRKTALDLMEGLFPVNISVLEMHRRKADVRRARENDRKSSGDVTEECPESELTAKQRSEDPTGKGNRALSGSGDDTKDLDDITCKKLELISSLRAKVRALEEDRELVLTEAKQCAERGEELEAAVRAACKPNELERYVMFIGDLEKVVSLLLCLSSRLARVQNAMRKIDGNTDAEEKQSLNERHKLLSRQREDAKDLKENLDRRERVVAGILAKYLTDQQLQAYRHFVQLKTSLLIEQKDLEEQIKFFKEQLENLEKSIPF", "length": 1313, "header": "tr|A0A8V0YKX7-1|A0A8V0YLG8_CHICK Computationally mapped isoform of Shroom family member 1 OS=Gallus gallus OX=9031 GN=SHROOM1 PE=1 SV=1 CANONICAL=A0A8V0YLG8-1" }, "locus": { "chromosome": "13", "start_pos": 16651569, "end_pos": 16642680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032852.1", "url": "https://www.ensembl.org/id/ENSGALT00010032852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019453.1", "url": "https://www.ensembl.org/id/ENSGALP00010019453.1" } ] } }, { "isoform_ac": "A0A8V0YLG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG8/entry", "sequence": { "sequence": "MAVSENETERWPCRHGGRIGALVEPTAPSDSSHLSPLPPLGSTEHILHLPGRADSAYSSFSGGSNVPEHQPPSLYEADCCSAAEQVPYMDSEYVRGIYNLSAASSALRCLQPYQAPSQSIPGVSHSPALAECSSGTPSHGTLEQGLPPPAAPPPSPPMRLDSYRVTRHLESTKGRGRQNSGGLSECNAQSAPCMDSRPVGVSHGQMGPGSSEPAMAAARRRTEENGEWNPSQKPVRRSNPHVYSRPSSFIFQEYLKTDSMANVPKILSTYGSAHVHNVSEEVKPRPYTSAHSSPGAAGDARGDVELQSAVLEHSRWKGSPLCAQCPLRAELPPDMGQEVSEDICDLKCMENALLIKNASRKSSICTDKNGCYDSKGEIGSIVRELLLNPQGKIQKSLLSSSCDAVELEQPPSGKLDHGNKQCCDNTEQMAFLRPKEDSSSQPLNEGCANSSSPGLNGQLEQEQPPAPYQKCQPELQQELLRQALDDPAGEQITRQVTPMLYYLSGGRAANTTHHSRLTQCPEGVRSSPKGFATSSHTASAWSKEMQRESSQSRKVEHRQCCANGDPLNEAEDVALGGPASSTEESSKNDYREKLKVAQKKVLRETSFKRKDLQMSLPVRLRQKPSKRPSIEHLRSFSLSSAHEDSKSAPCSASCLESLEGFNTDAEIKRPQAGRIGGRKRATKEEKKLCYSEPEKLNQLADKEAQGSTEQDMARRRTSESRGRALSSSSISRTELKQIQHTALMEYMERKISQRPGSTQHAPPHKPALQMGPLHPKWPPGRSSNPGESRKTPSNGASCQVFSEEAAPDVFPPSSPVPPPNTGGGCGVVPAKPSLHPAAPDRSCSPECVSAQSVPLSGAAAQGQEVEHPSMQAADSRAVPPARPCGNHISTPSSHDPREDGCQNHEHRDSVVGSSVCQHSEELAASTSIPSPRKGSRDNAQVEKKSRSGSQTGNALTTCPELQPKTSSAAAVQGNAAILVLPAQPQQGDGGKASAWGVKKAAAHNGRDGVLQEGETELPQRRLWSPEDRCYEELTMDLIAKDSSLVDVLMPYPDRKTALDLMEGLFPVNISVLEMHRRKADVRRARENDRKSSGDVTEECPESELTAKQRSEDPTGKGNRALSGSGDDTKDLDDITCKKKLGCTPSQLELISSLRAKVRALEEDRELVLTEAKQCAERGEELEAAVRAACKPNELERYVMFIGDLEKVVSLLLCLSSRLARVQNAMRKIDGNTDAEEKQSLNERHKLLSRQREDAKDLKENLDRRERVVAGILAKYLTDQQLQAYRHFVQLKTSLLIEQKDLEEQIKFFKEQLENLEKSIPF", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-5(IV) chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134091" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134091.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134091" } ] }, { "annotation": "Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YT57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT57#function" }, { "database": "UniProtKB", "id": "ARBA00003696", "url": "https://www.uniprot.org/uniprotkb/ARBA00003696#function" }, { "database": "UniProtKB", "id": "A0A8V0YSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS0#function" }, { "database": "UniProtKB", "id": "A0A8V0YSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW7#function" }, { "database": "UniProtKB", "id": "A0A8V0YUS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS8#function" }, { "database": "UniProtKB", "id": "A0A8V0YZJ2", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01413", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01413", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1566977", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2243919", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2243919", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000171", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPSGPPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1695, "header": "tr|A0A8V0YLG2-1|A0A8V0YLG2_CHICK Isoform 1 of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE8/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPSGPPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1643, "header": "tr|A0A8V0YLE8-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037689.1", "url": "https://www.ensembl.org/id/ENSGALT00010037689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021778.1", "url": "https://www.ensembl.org/id/ENSGALP00010021778.1" } ] } }, { "isoform_ac": "A0A8V0YLG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPSGPPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1695, "header": "tr|A0A8V0YLG2-1|A0A8V0YLG2_CHICK Isoform 1 of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037726.1", "url": "https://www.ensembl.org/id/ENSGALT00010037726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021793.1", "url": "https://www.ensembl.org/id/ENSGALP00010021793.1" } ] } }, { "isoform_ac": "A0A8V0YLH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH1/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1689, "header": "tr|A0A8V0YLH1-1|A0A8V0YLH1_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037746.1", "url": "https://www.ensembl.org/id/ENSGALT00010037746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021803.1", "url": "https://www.ensembl.org/id/ENSGALP00010021803.1" } ] } }, { "isoform_ac": "A0A8V0YSS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS0/entry", "sequence": { "sequence": "MSDASVKGLMLPLMHVMWIKACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1678, "header": "tr|A0A8V0YSS0-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13927912, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037649.1", "url": "https://www.ensembl.org/id/ENSGALT00010037649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021760.1", "url": "https://www.ensembl.org/id/ENSGALP00010021760.1" } ] } }, { "isoform_ac": "A0A8V0YSW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW7/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPSGPPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1650, "header": "tr|A0A8V0YSW7-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037760.1", "url": "https://www.ensembl.org/id/ENSGALT00010037760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021810.1", "url": "https://www.ensembl.org/id/ENSGALP00010021810.1" } ] } }, { "isoform_ac": "A0A8V0YT57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT57/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1596, "header": "tr|A0A8V0YT57-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037709.1", "url": "https://www.ensembl.org/id/ENSGALT00010037709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021787.1", "url": "https://www.ensembl.org/id/ENSGALP00010021787.1" } ] } }, { "isoform_ac": "A0A8V0YUS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS8/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1602, "header": "tr|A0A8V0YUS8-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037769.1", "url": "https://www.ensembl.org/id/ENSGALT00010037769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021816.1", "url": "https://www.ensembl.org/id/ENSGALP00010021816.1" } ] } }, { "isoform_ac": "A0A8V0YZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ2/entry", "sequence": { "sequence": "MERRRRSRSPAVGCVVLLLLGCWGPREAAAAACHGCTSVTKCDCSGVKGEKGERGFPGLEGQPGLPGFPGPEGPPGPRGAKGDDGLPGPIGPKGIRGPPGLPGFPGTPGLPGLPGQDGPPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGLPGMKGEAGEIITSLLPGQKGDQGFPGLPGIPGPPGSIGIPGPVGPPGPPGLTGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIGEQKRPNDIEFQKGDQGIPGDPGPPGLPGPQGPPGLPGGIKGEKGEQGEPGKRGKPGKDGEPGQPGRDGLPGGPGVNGVPGRDGEKGEKGDVGPPGPPGSVITRPGIDATVGPKGSKGLPGLPGAKGERGFSGRPGPPGLPGSPGITTVGPPGPPGLPGERGQKGDPGLPGVSIPGQPGLDGPQGPPGPPGPPGPPAPSVPPGEGLCERGPPGPPGIPGQQGFAGERGQKGDQGDTCFNCIGTGISGPPGERGPPGPPGSPGSPGFPGPKGEKGLPGLTGLVGPPGFPGPPGAPGRPGPKGDPGDVLASPRMKGDKGDPGFPGPPGLPGIDGTPGRDGLPGLPGPKGEPGSVAFKGEMGIPGDPGAPGLPGDKGLPGPPGFGPQGSPGEKGIQGVSGRPGPPGVPGPKGDPGQTITEPGVPGPPGPPGRNGDPGLPGDPGQPGQRGLSGIPGAKGEPGIPGIGLPGPPGPKGFPGTPGPPGAPGTPGRPGLDGPPGPPGFPGQKGDRGFGVPGPPGPPGPPGIKGVQGPKGDPGFPGNPGLPGRAGFDGTPGPKGDPGPSGPPGLPGPPGIPGIGGQGPPGPPGPPGPVGPPGLQGVPGEKGDPGPPGFDVPGPPGDQGTPGYPGPPGLPGPQGSPGPPGRDGIPGFPGAKGEMGVMGAPGPPGPPGTPGRSGLPGLKGNNGLPGPPGPPGPLGQKGVKGEAGLPGPPGTVDPKQLGAKGEKGEPGVPGIPGLSGQKGYQGLPGDPGPPGLSGPPGAPGLPGVKGDMGLPGQPGPTGPPGLKGAMGEMGLPGPPGSKGSQGIAGRPGQPGPAGFPGLKGEKGDPGLSSIGIPGLPGPKGDLGLPGYPGSPGSKGIAGNPGLPGLPGSPGAKGEPGLPGFPGTPGIPGPKGIEGPPGNPGLPGPPGPVGDTGRPGPPGPPGEKGQPGRDGIPGPAGQKGEPGLPGFGRPGPPGLPGLSGQKGELGLPGPPGPPGLPGLKGEPGFQGFPGLQGPPGPPGLPGPPLEGPKGSPGPPGVPGRPGPPGSPGPEGPRGPPGSGGLKGEKGNPGQPGPPGLTGQKGDQGPPGRQGDPGRPGLNGMKGDPGVPGVPGFPGMKGPTGPAGPAGLTGSQGLPGPPGPPGLPGTIGRSIVVKGDPGPPGPPGLPGSKGPPGLAGPQGLPGPVGVPGDPGRDGLPGFDGPAGRKGERGLPGQPGSRGIQGPPGPDGLQGPPGPPGTASVAHGFLITRHSQTRDTPLCPQGTSRIYDGFSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMEPLTGQNIQPFISRCVVCEAPAMVIAVHSQTIQIPSCPPGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVEVSEMFSKPQSETLKAGDLRTRISRCQVCMKKT", "length": 1692, "header": "tr|A0A8V0YZJ2-1|A0A8V0YLG2_CHICK Computationally mapped isoform of Collagen type IV alpha 5 chain OS=Gallus gallus OX=9031 GN=COL4A5 PE=1 SV=1 CANONICAL=A0A8V0YLG2-1" }, "locus": { "chromosome": "4", "start_pos": 13939243, "end_pos": 13862510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037667.1", "url": "https://www.ensembl.org/id/ENSGALT00010037667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021769.1", "url": "https://www.ensembl.org/id/ENSGALP00010021769.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1024, "start_aa": "Thr", "end_pos": 1024, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1024", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 107, "start_aa": "Thr", "end_pos": 107, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr107", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1130, "start_aa": "Thr", "end_pos": 1130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1130", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 581, "start_aa": "Thr", "end_pos": 581, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr581", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 724, "start_aa": "Thr", "end_pos": 724, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 733, "start_aa": "Thr", "end_pos": 733, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr733", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 798, "start_aa": "Thr", "end_pos": 798, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr798", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 868, "start_aa": "Thr", "end_pos": 868, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr868", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 916, "start_aa": "Thr", "end_pos": 916, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr916", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422348", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422348", "resource": "KEGG Pathway" }, { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1566977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566977", "resource": "Reactome", "description": "Fibronectin matrix formation" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-2243919", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2243919", "resource": "Reactome", "description": "Crosslinking of collagen fibrils" }, { "id": "R-GGA-3000171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "resource": "Reactome", "description": "Non-integrin membrane-ECM interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LJB9-1", "protein_name": "Collagen type IV alpha 5 chain", "gene_name": "Col4a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1691 }, "evidence": [ { "id": "A0A8V0YLG2", "url": "https://omabrowser.org/oma/group/A0A8V0YLG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08120-1", "protein_name": "Collagen alpha-1(IV) chain", "gene_name": "Col4a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 1779 }, "evidence": [ { "id": "A0A8V0YLG2", "url": "https://omabrowser.org/oma/group/A0A8V0YLG2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P29400-1", "protein_name": "Collagen alpha-5(IV) chain", "gene_name": "COL4A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1685 }, "evidence": [ { "id": "A0A8V0YLG2", "url": "https://omabrowser.org/oma/group/A0A8V0YLG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63ZW6-1", "protein_name": "Collagen alpha-5(IV) chain", "gene_name": "Col4a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1691 }, "evidence": [ { "id": "A0A8V0YLG2", "url": "https://omabrowser.org/oma/group/A0A8V0YLG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" }, { "name": "collagen trimer", "id": "GO:0005581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" }, { "name": "collagen type IV trimer", "id": "GO:0005587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG2" }, { "id": "PS51403", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51403" } ], "ann_type": 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This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"MAAGAARCRRIFLNHLDSYCGRSIGEYLSGCVVGASLESVEEEEEENEDHLEAEVSRRPKEGLYQIVGTLSKPESTKPSFAEETYAVSSQKELLSYLLECDIILYNITEDANQIKEATWAASALRMEIEHFATPKMFILISTVMSWAKSKPPDPEDSEIPFTEEDYRRRKPHPNFIDHINAEKLVLKLGKNNKHAFSTYVVASGIQYGAGEGVLHYFFKIGWLSETAAIPVFGHGNNCIPTIHVRDLAAVLQNIADHRPKFHYILAVDESAHTFQELIKCISKNVGPGKIEKIPEENAFLSKELTQMHVDMLLVNLRMEAMFLKETFNIKWVAQTGLVENIEQIVEEYKQSRGLLPLKVYIHGPPGVGKSTIAEEICKHYKLHHIKIKDVISESIAKLEKIVAPKEVDSDSVRQEGEEGEDDEEEGENLEEAHELLAEIKESMEQNAGRLDDQYVIKLFKDKLKSMPCRNQGYVLDGFPKTYDQARDLFNLEEEEEIASKIPKYDKIITPEFVISLTASDEFLKNRIINLPESVVAGTHYTQDRFLQSLNNFREINVDDETVLNYFDELEIHPQFIDVAKYEDSENRFVVKEIIKEIGEPRNYGLTDEEKESLERKAAEECLAREAKEKAERERREAEERAERIANWEEWNKHLEEVKKQEQELLEAQSIPLRNYLMKHVMPTLMQGLNECCKIRPDDPVDFLAEYLFKNNPDVK", "length": 715, "header": "tr|A0A8V0YLF7-1|A0A8V0YLF7_CHICK Isoform 1 of Adenylate kinase 7 OS=Gallus gallus OX=9031 GN=AK7 PE=1 SV=1 CANONICAL=A0A8V0YLF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF7/entry", "sequence": { 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"database": "Ensembl Transcript", "id": "ENSGALT00010037715.1", "url": "https://www.ensembl.org/id/ENSGALT00010037715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021788.1", "url": "https://www.ensembl.org/id/ENSGALP00010021788.1" } ] } }, { "isoform_ac": "A0A8V0YUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUP1/entry", "sequence": { "sequence": "MAAGAARCRRIFLNHLDSYCGRSIGEYLSGCVVGASLESVEEEEEENEDHLEAEVSRRPKEGLYQIVGTLSKPESTKPSFAEETYAVSSQKELLSYLLECDIILYNITEDANQIKEATWAASALRMEIEHFATPKMFILISTVMSWAKSKPPDPEDSEIPFTEEDYRRRKPHPNFIDHINAEKLVLKLGKNNKHAFSTYVVASGIQYGAGEGVLHYFFKIGWLSETAAIPVFGHGNNCIPTIHVRDLAAVLQNIADHRPKFHYILAVDESAHTFQELIKCISKNVGPGKIEKIPEENAFLSKELTQMHVDMLLVNLRMEAMFLKETFNIKWVAQTGLVENIEQIVEEYKQSRGLLEKIVAPKEVDSDSVRQEGEEGEDDEEEGENLEEAHELLAEIKESMEQNAGRLDDQYVIKLFKDKLKSMPCRNQGYVLDGFPKTYDQARDLFNLEEEEEIASKIPKYDKIITPEFVISLTASDEFLKNRIINLPESVVAGTHYTQDRFLQSLNNFREINVDDETVLNYFDELEIHPQFIDVAKYEDSENRFVVKEIIKEIGEPRNYGLTDEEKESLERKAAEECLAREAKEKAERERREAEERAERIANWEEWNKHLEEVKKQEQELLEAQSIPLRNYLMKHVMPTLMQGLNECCKIRPDDPVDFLAEYLFKNNPDVK", "length": 672, "header": "tr|A0A8V0YUP1-1|A0A8V0YLF7_CHICK Computationally mapped isoform of Adenylate kinase 7 OS=Gallus gallus OX=9031 GN=AK7 PE=1 SV=1 CANONICAL=A0A8V0YLF7-1" }, "locus": { "chromosome": "5", "start_pos": 45989284, "end_pos": 45970790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", 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], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF7" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527585" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040527585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527585" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GABRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3", "locus": { "chromosome": "4", "start_pos": 66719788, "end_pos": 66668470, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013677", "url": "https://www.ensembl.org/id/ENSGALG00010013677" } ] } } ], "crossref": [ { "id": "A0A8V0YLH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422771", "url": "https://www.ncbi.nlm.nih.gov/gene/422771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MGSWEAF", "url": "https://omabrowser.org/oma/group/MGSWEAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH3", "url": "https://www.orthodb.org/?gene=A0A8V0YLH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040527585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAWGVPASRWSRCRGARLLLLLLTVRLGSGADKADDEDDEDLTVNKTWVLAPKIHGGDVTHILDSLLQGYDNKLRPDIGVRTTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWYDSRLKFNSSMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPRNEIEYKWKKTSVEVADPKYWRLYQFAFVGLRNTTEISHTLSGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNRKGDKGKDKKAKPKPSKPSAIAVRPGSTLIPINNINHLPERDDDYGYECLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWIGYLYL", "length": 464, "header": "tr|A0A8V0YLH3-1|A0A8V0YLH3_CHICK Isoform 1 of Gamma-aminobutyric acid type A receptor subunit gamma1 OS=Gallus gallus OX=9031 GN=GABRG1 PE=3 SV=1 CANONICAL=A0A8V0YLH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3/entry", "sequence": { "sequence": "MDAWGVPASRWSRCRGARLLLLLLTVRLGSGADKADDEDDEDLTVNKTWVLAPKIHGGDVTHILDSLLQGYDNKLRPDIGVRTTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWYDSRLKFNSSMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPRNEIEYKWKKTSVEVADPKYWRLYQFAFVGLRNTTEISHTLSGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNRKGDKGKDKKAKPKPSKPSAIAVRPGSTLIPINNINHLPERDDDYGYECLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWIGYLYL", "length": 464, "header": "tr|A0A8V0YLH3-1|A0A8V0YLH3_CHICK Isoform 1 of Gamma-aminobutyric acid type A receptor subunit gamma1 OS=Gallus gallus OX=9031 GN=GABRG1 PE=3 SV=1 CANONICAL=A0A8V0YLH3-1" }, "locus": { "chromosome": "4", "start_pos": 66716928, "end_pos": 66668551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032861.1", "url": "https://www.ensembl.org/id/ENSGALT00010032861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019456.1", "url": "https://www.ensembl.org/id/ENSGALP00010019456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1S3S9-1", "protein_name": "Gamma-aminobutyric acid type A receptor subunit gamma1", "gene_name": "GABRG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSWKALLFSPFLLWSQRRGVRLMFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNTTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNKKAKTTRERKPKNKASMSSGLHPGSTLIPMNSLTLPQGEDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL", "length": 465 }, "evidence": [ { "id": "A0A8V0YLH3", "url": "https://omabrowser.org/oma/group/A0A8V0YLH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6Q4V7-1", "protein_name": "Gamma-aminobutyric acid type A receptor subunit gamma1", "gene_name": "GABRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSWKALLFSPFLLWKQRRGVRLMFLLLTVHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNTTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNKKVKTTREKKPKLKTSMSSGLHPGSTLIPMNSLSLPQGEDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL", "length": 465 }, "evidence": [ { "id": "A0A8V0YLH3", "url": "https://omabrowser.org/oma/group/A0A8V0YLH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23574-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-1", "gene_name": "Gabrg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSGKVFLFSPSLLWSQTRGVRLIFLLLTLHLGNCIDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRDRKLKSKTSVSPGLHAGSTLIPMNNISMPQGEDDYGYQCLEGKDCATFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL", "length": 465 }, "evidence": [ { "id": "A0A8V0YLH3", "url": "https://omabrowser.org/oma/group/A0A8V0YLH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N1C3-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-1", "gene_name": "GABRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL", "length": 465 }, "evidence": [ { "id": "A0A8V0YLH3", "url": "https://omabrowser.org/oma/group/A0A8V0YLH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0Y8-1", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-1", "gene_name": "Gabrg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSGKAFLFSPSLLWSQTRGVRLIFLLLTLHLGNCVDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRGRKLKNKTSASPGLHAGSTLIPMNSISLPQGEDDYGYQCLEGKDCTSFFCCFDDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL", "length": 465 }, "evidence": [ { "id": "A0A8V0YLH3", "url": "https://omabrowser.org/oma/group/A0A8V0YLH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "GABA-A receptor complex", "id": "GO:1902711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "inhibitory synapse assembly", "id": "GO:1904862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GABA-A receptor activity", "id": "GO:0004890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" }, { "name": "GABA-gated chloride ion channel activity", "id": "GO:0022851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022851", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLH7-1", "uniprot_ac": "A0A8V0YLH7", "uniprot_id": "A0A8V0YLH7_CHICK", "mass": { "chemical_mass": 57525.0, "monoisotopic_mass": 57525.0 }, "refseq": { "ac": "NP_990695", "name": "neuronal acetylcholine receptor subunit alpha-6 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" }, "gene_names": [ { "name": "CHRNA6", "type": "recommended", "evidence": [ { "id": "A0A8V0YLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7" } ] }, { "name": "CHRNA6", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] } ], "protein_names": [ { "name": "Cholinergic receptor nicotinic alpha 6 subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0YLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7/entry#names_and_taxonomy" } ] }, { "name": "alpha 6 nicotinic acetylcholine receptor subunit", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] }, { "name": "cholinergic receptor, nicotinic, alpha 6 (neuronal)", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] }, { "name": "cholinergic receptor, nicotinic, alpha polypeptide 6", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] }, { "name": "neuronal acetylcholine receptor subunit alpha-6 precursor", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] }, { "name": "neuronal acetylcholine receptor subunit alpha-6", "type": "synonym", "evidence": [ { "id": "NP_990695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: U48860.1, X83889.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHRNA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7", "locus": { "chromosome": "Z", "start_pos": 54300029, "end_pos": 54290664, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013675", "url": "https://www.ensembl.org/id/ENSGALG00010013675" } ] } } ], "crossref": [ { "id": "A0A8V0YLH7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396321", "url": "https://www.ncbi.nlm.nih.gov/gene/396321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396321", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKDTKLH", "url": "https://omabrowser.org/oma/group/HKDTKLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH7", "url": "https://www.orthodb.org/?gene=A0A8V0YLH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNB7", "url": "https://www.orthodb.org/?gene=A0A8V0YNB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTA7", "url": "https://www.orthodb.org/?gene=A0A8V0YTA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-629594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-629597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990695", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YLH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRWDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVFGTAGLFIQPLIADT", "length": 494, "header": "tr|A0A8V0YLH7-1|A0A8V0YLH7_CHICK Isoform 1 of Cholinergic receptor nicotinic alpha 6 subunit OS=Gallus gallus OX=9031 GN=CHRNA6 PE=3 SV=1 CANONICAL=A0A8V0YLH7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLH7/entry", "sequence": { "sequence": "MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRWDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVFGTAGLFIQPLIADT", "length": 494, "header": "tr|A0A8V0YLH7-1|A0A8V0YLH7_CHICK Isoform 1 of Cholinergic receptor nicotinic alpha 6 subunit OS=Gallus gallus OX=9031 GN=CHRNA6 PE=3 SV=1 CANONICAL=A0A8V0YLH7-1" }, "locus": { "chromosome": "Z", "start_pos": 54299488, "end_pos": 54291176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032874.1", "url": "https://www.ensembl.org/id/ENSGALT00010032874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019461.1", "url": "https://www.ensembl.org/id/ENSGALP00010019461.1" } ] } }, { "isoform_ac": "A0A8V0YNB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB7/entry", "sequence": { "sequence": "MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRWDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEGNNVFCSPTSTEEMILEASALFRCTELCCYGHVPYE", "length": 490, "header": "tr|A0A8V0YNB7-1|A0A8V0YNB7_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic alpha 6 subunit OS=Gallus gallus OX=9031 GN=CHRNA6 PE=3 SV=1 CANONICAL=A0A8V0YLH7-1" }, "locus": { "chromosome": "Z", "start_pos": 54298407, "end_pos": 54291176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032863.1", "url": "https://www.ensembl.org/id/ENSGALT00010032863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019457.1", "url": "https://www.ensembl.org/id/ENSGALP00010019457.1" } ] } }, { "isoform_ac": "A0A8V0YTA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTA7/entry", "sequence": { "sequence": "MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRWDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVREVASKLGTRSHLQHSMGE", "length": 474, "header": "tr|A0A8V0YTA7-1|A0A8V0YLH7_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic alpha 6 subunit OS=Gallus gallus OX=9031 GN=CHRNA6 PE=3 SV=1 CANONICAL=A0A8V0YLH7-1" }, "locus": { "chromosome": "Z", "start_pos": 54296590, "end_pos": 54291176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032857.1", "url": "https://www.ensembl.org/id/ENSGALT00010032857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019455.1", "url": "https://www.ensembl.org/id/ENSGALP00010019455.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396321", "resource": "KEGG Pathway" }, { "id": "R-GGA-629594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629594", "resource": "Reactome", "description": "Highly calcium permeable postsynaptic nicotinic acetylcholine receptors" }, { "id": "R-GGA-629597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-629597", "resource": "Reactome", "description": "Highly calcium permeable nicotinic acetylcholine receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MQ06-1", "protein_name": "Cholinergic receptor nicotinic alpha 6 subunit", "gene_name": "CHRNA6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPRGGQGALRFALCVWWCVFALCFKGCAGCASEERLFHKLFAHYNQFIRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLRHIWNDYKLRWDPTEYDGIETLRVPAEMIWKPDIVLYNNAVGDFQVKGKTKALLKYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHSMPTWVKAVFLRLLPQMLMMKRPLDKMKETGAHRNPKGVSSRPAKVKFEHHKEPRLLKECCHCHRSGEPATSKRRLSHQPLQWMAENSELSPEVEDVIDSVHFIAENMKTQNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGHS", "length": 494 }, "evidence": [ { "id": "A0A8V0YLH7", "url": "https://omabrowser.org/oma/group/A0A8V0YLH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P43143-1", "protein_name": "Neuronal acetylcholine receptor subunit alpha-6", "gene_name": "Chrna6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNGWGRGDLRSGLCLWICGFLAFFKGSRGCVSEEQLFHTLFAHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTEYDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPKWVKTMFLQVFPSILMMRRPLDKTKEMDGVKDPKTHTKRPAKVKFTHRKEPKLLKECRHCHKSSEIAPGKRLSQQPAQWVTENSEHPPDVEDVIDSVQFIAENMKSHNETKEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQPLLGNTGAS", "length": 493 }, "evidence": [ { "id": "A0A8V0YLH7", "url": "https://omabrowser.org/oma/group/A0A8V0YLH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15825-1", "protein_name": "Neuronal acetylcholine receptor subunit alpha-6", "gene_name": "CHRNA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS", "length": 494 }, "evidence": [ { "id": "A0A8V0YLH7", "url": "https://omabrowser.org/oma/group/A0A8V0YLH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0W9-1", "protein_name": "Neuronal acetylcholine receptor subunit alpha-6", "gene_name": 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"https://www.ebi.ac.uk/interpro/entry/IPR028375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLV1", "url": "https://www.orthodb.org/?gene=A0A8V0YLV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV42", "url": "https://www.orthodb.org/?gene=A0A8V0YV42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z001", "url": "https://www.orthodb.org/?gene=A0A8V0Z001", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z006", "url": "https://www.orthodb.org/?gene=A0A8V0Z006", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5673000", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5674135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z001", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z001", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z001-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z001-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z006", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z006", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z006-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z006-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTRTPLPTVNERDTENHTSHGDGRQEVSSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPTKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSISSSQKQRRYSDHAGPSIPPVVAYPKRSQTSTTDSDLKEEGIQSRKSSSSAVAGRGIAPASPMLGNASNPNKADIPERKKSSAVPSLLSRSWKIDRQLGHISTLFLCKDRGKNNTAPGAMTRRNTYVCSERTTADRHSVIQNGKENSLTEMFAYAASPASVCTTSFSSVRLRHQKSMSMSASVHTKMMLPPIDNGADNFRPITIPDQRTPVASTHSISSATTPDRIRFPRGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRTRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRFEGSSRNVAVDQKDENKEAKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL", "length": 834, "header": "tr|A0A8V0YLV1-1|A0A8V0YLV1_CHICK Isoform 1 of MAP/microtubule affinity-regulating kinase 3 OS=Gallus gallus OX=9031 GN=MARK3 PE=1 SV=1 CANONICAL=A0A8V0YLV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1/entry", "sequence": { "sequence": "MSTRTPLPTVNERDTENHTSHGDGRQEVSSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPTKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSISSSQKQRRYSDHAGPSIPPVVAYPKRSQTSTTDSDLKEEGIQSRKSSSSAVAGRGIAPASPMLGNASNPNKADIPERKKSSAVPSLLSRSWKIDRQLGHISTLFLCKDRGKNNTAPGAMTRRNTYVCSERTTADRHSVIQNGKENSLTEMFAYAASPASVCTTSFSSVRLRHQKSMSMSASVHTKMMLPPIDNGADNFRPITIPDQRTPVASTHSISSATTPDRIRFPRGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRTRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRFEGSSRNVAVDQKDENKEAKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL", "length": 834, "header": "tr|A0A8V0YLV1-1|A0A8V0YLV1_CHICK Isoform 1 of MAP/microtubule affinity-regulating kinase 3 OS=Gallus gallus OX=9031 GN=MARK3 PE=1 SV=1 CANONICAL=A0A8V0YLV1-1" }, "locus": { "chromosome": "5", "start_pos": 49812766, "end_pos": 49754338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038013.1", "url": "https://www.ensembl.org/id/ENSGALT00010038013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021932.1", "url": "https://www.ensembl.org/id/ENSGALP00010021932.1" } ] } }, { "isoform_ac": "A0A8V0YV42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV42/entry", "sequence": { "sequence": "MSTRTPLPTVNERDTENDVGSSLGEGFCEKHTSHGDGRQEVSSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPTKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSISSSQKQRRYSDHAGPSIPPVVAYPKRSQTSTTDSDLKEEGIQSRKSSSSAVAGRGIAPASPMLGNASNPNKADIPERKKSSAVPSNNTAPGAMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSATTPDRIRFPRGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRTRGSTNLFSKLTSKLTRSRNVAVDQKDENKEAKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL", "length": 742, "header": "tr|A0A8V0YV42-1|A0A8V0YLV1_CHICK Computationally mapped isoform of MAP/microtubule affinity-regulating kinase 3 OS=Gallus gallus OX=9031 GN=MARK3 PE=1 SV=1 CANONICAL=A0A8V0YLV1-1" }, "locus": { "chromosome": "5", "start_pos": 49812766, "end_pos": 49754338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038020.1", "url": "https://www.ensembl.org/id/ENSGALT00010038020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021935.1", "url": "https://www.ensembl.org/id/ENSGALP00010021935.1" } ] } }, { "isoform_ac": "A0A8V0Z001-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z001/entry", "sequence": { "sequence": "MSTRTPLPTVNERDTENHTSHGDGRQEVSSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPTKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSISSSQKQRRYSDHAGPSIPPVVAYPKRSQTSTTDSDLKEEGIQSRKSSSSAVAGRGIAPASPMLGNASNPNKADIPERKKSSAVPSLLSRSWKIDRQLGHISTLFLCKDRGKNNTAPGAMTRRNTYVCSERTTADRHSVIQNGKENSVRLRHQKSMSMSASVHTKMMLPPIDNGADNFRPIGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRTRGSTNLFSKLTSKLTRRNMSFRFIKSRNVAVDQKDENKEAKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL", "length": 770, "header": "tr|A0A8V0Z001-1|A0A8V0YLV1_CHICK Computationally mapped isoform of MAP/microtubule affinity-regulating kinase 3 OS=Gallus gallus OX=9031 GN=MARK3 PE=1 SV=1 CANONICAL=A0A8V0YLV1-1" }, "locus": { "chromosome": "5", "start_pos": 49812766, "end_pos": 49754338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038017.1", "url": "https://www.ensembl.org/id/ENSGALT00010038017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021933.1", "url": "https://www.ensembl.org/id/ENSGALP00010021933.1" } ] } }, { "isoform_ac": "A0A8V0Z006-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z006/entry", "sequence": { "sequence": "MSTRTPLPTVNERDTENHTSHGDGRQEVSSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPTKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSISSSQKQRRYSDHAGPSIPPVVAYPKRSQTSTTDSDLKEEGIQSRKSSSSAVAGRGIAPASPMLGNASNPNKADIPERKKSSAVPSNNTAPGAMTRRNTYVCSERTTADRHSVIQNGKENSLTEMFAYAASPASVCTTSFSSVRLRHQKSMSMSASVHTKMMLPPIDNGADNFRPITIPDQRTPVASTHSISSATTPDRIRFPRGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRTRGSTNLFSKLTSKLTRRLPTEYERNGRFEGSSRNVAVDQKDENKEAKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL", "length": 799, "header": "tr|A0A8V0Z006-1|A0A8V0YLV1_CHICK Computationally mapped isoform of MAP/microtubule affinity-regulating kinase 3 OS=Gallus gallus OX=9031 GN=MARK3 PE=1 SV=1 CANONICAL=A0A8V0YLV1-1" }, "locus": { "chromosome": "5", "start_pos": 49812766, "end_pos": 49754338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038023.1", "url": "https://www.ensembl.org/id/ENSGALT00010038023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021938.1", "url": "https://www.ensembl.org/id/ENSGALP00010021938.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5673000", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "resource": "Reactome", "description": "RAF activation" }, { "id": "R-GGA-5674135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "resource": "Reactome", "description": "MAP2K and MAPK activation" }, { "id": "R-GGA-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" }, { "id": "R-GGA-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "negative regulation of protein localization to nucleus", "id": "GO:1900181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", 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"A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], 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"Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-5672948", "name": "MARK3 phosphorylates KSR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672948" } ] }, { "id": "R-GGA-5672954", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672954", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672954" } ] }, { "id": "R-GGA-5672958", "name": "YWHAB dimer dissociates from KSR1:MARK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672958" } ] }, { "id": "R-GGA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0ZZ54-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672966" } ] }, { "id": "R-GGA-5672969", "name": "Phosphorylation of RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0YNY4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672969" } ] }, { "id": "R-GGA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672973" } ] }, { "id": "R-GGA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672978" } ] }, { "id": "R-GGA-5674019", "name": "BRAP binds KSR1:MARK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0ZZ54-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5674019", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674019" } ] }, { "id": "R-GGA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9653108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9653108" } ] }, { "id": "R-GGA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657599" } ] }, { "id": "R-GGA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657603" } ] }, { "id": "R-GGA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657606" } ] }, { "id": "R-GGA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657608" } ] }, { "id": "R-GGA-9926483", "name": "MARK3 phosphorylates MITF-M on S173", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-9926333" ], "output_participant_list": [ "R-GGA-9926321" ], "enzyme_list": [ "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-9926483", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9926483" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-9926321", "participant_name": "phospho-MITF [cytosol]", "crossref": [ { "id": "ENSGALP00010032326", "database": "ENSEMBL", "url": "" }, { "id": "XP_046782019.1", "database": "RefSeq", "url": "" }, { "id": "A0A3Q2U6P0", "database": "UniProt", "url": "" }, { "id": "XP_015148456.2", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010022062", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010053663", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9926333", "participant_name": "MITF [cytosol]", "crossref": [ { "id": "A0A3Q2U6P0", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010022062", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010032326", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010053663", "database": "ENSEMBL", "url": "" }, { "id": "XP_046782019.1", "database": "RefSeq", "url": "" }, { "id": "XP_015148456.2", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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{ "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZ54", "gene_name": "BRAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": 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"IERKGLVSLGLGAAKGTGMEGGEPSGLPGPKAAAPVSPQGDPLGGSPVPSLTISLGFLCFPPLSMRQAQALGTSLFSSPQDLGSEEPLEERGSAAMANRSHLQQEGPLEASDDYRCAICLDNISNMACVDPCFHRFCSGCIRRWATTRAVCPLCRQPIDPAGMKANSIPAKTRTVLSPHSIPSPACSGPTLSKTSKSPSDFLSFDKNTETAFP", "length": 213, "header": "tr|A0A8V0YLW2-1|A0A8V0YLW2_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YLW2-1" }, "locus": { "chromosome": "Z", "start_pos": 15228293, "end_pos": 15225957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033132.1", "url": "https://www.ensembl.org/id/ENSGALT00010033132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019587.1", "url": "https://www.ensembl.org/id/ENSGALP00010019587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": 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"n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW2" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 155, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLW8-1", "uniprot_ac": "A0A8V0YLW8", "uniprot_id": "A0A8V0YLW8_CHICK", "mass": { "chemical_mass": 97136.0, "monoisotopic_mass": 97136.0 }, "refseq": {}, "gene_names": [ { "name": "CUL4B", "type": "recommended", "evidence": [ { "id": "A0A8V0YLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8" } ] } ], "protein_names": [ { "name": "Cullin-4B", "type": "recommended", "evidence": [ { "id": "A0A8V0YLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CUL4B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8", "locus": { "chromosome": "4", "start_pos": 16372703, "end_pos": 16350868, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012295", "url": "https://www.ensembl.org/id/ENSGALG00010012295" } ] } } ], "crossref": [ { "id": "A0A8V0YLW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLW8", "url": "https://www.orthodb.org/?gene=A0A8V0YLW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696394", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696400", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696400", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YLW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CANONICAL=A0A8V0YLW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW8/entry", "sequence": { "sequence": 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CANONICAL=A0A8V0YLW8-1" }, "locus": { "chromosome": "4", "start_pos": 16370708, "end_pos": 16351067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029429.1", "url": "https://www.ensembl.org/id/ENSGALT00010029429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017097.1", "url": "https://www.ensembl.org/id/ENSGALP00010017097.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-GGA-5696394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696394", "resource": "Reactome", "description": "DNA Damage Recognition in GG-NER" }, { "id": "R-GGA-5696395", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "resource": "Reactome", "description": "Formation of Incision Complex in GG-NER" }, { "id": "R-GGA-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-GGA-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { 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}, { "name": "OB receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0YLX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6/entry#names_and_taxonomy" } ] }, { "name": "oncostatin-M-specific receptor subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937258" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937258" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSMR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6", "locus": { "chromosome": "Z", "start_pos": 12733210, "end_pos": 12700944, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013344", "url": "https://www.ensembl.org/id/ENSGALG00010013344" } ] } } ], "crossref": [ { "id": "A0A8V0YLX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLX6", "database": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-6788467", "resource": "Reactome", "description": "IL-6-type cytokine receptor ligand interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JFG1-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "Osmr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSYRLQTIRPMAFSVALHPAFLLVVLSLKTSRSEVLGEPFQLTPEILTVSTESKLQQVNLQWTVPNLTHQELKMAFQIEISRINTSNIVWVENYSTTVKWNQLLHWNWKSEIPLECVTHFIRIRAMVDDAKYLPQNSWSNWSSWKEVSVQVSVAPNTLLIFPDNKLLEEGSNVTICLLYGQYLYNVSCMLQKEPIHGEQLDSHVSLIKLNNVVFHSVSGTNIHCKAMNATKMIFGTVLFVSKVLEEPKNFSCETQDFKTLKCSWEPGVDTALVWSQQDSQSYTLYESFSGRRELCDHRNSHNWQITDDSQETYNFTLTTENNLRKRSVNLIFNLTHRVHQKAPHDVTLENIDARKANMTWKVLSRGNNYILLCQIELQHEREVIHEHNVSVHMSASYLFSDLEPDTKYKARVRCADANHFWKWSDWAQKEFCTPEAAPSQALDVWRQVRSENGSYVVTLFWKPLLKSQANGKIVSYNIVVENQDRLSESEHYSVPAPALGTQLSLDPCSYKIHITANNSVGVSPESVMVLSNDSGHEEVHEKRIKGTKDGFHISWEPTSGDALGYVVDWCVHSRDQHCDLQWKNLGPNTTSTNITSGAFKPGVRYNFRIFEKSMQQKAQLLEKQTGYTQELAPLENPEVTINNFTSNSFILSWPSYDSDFQSAFIEGYHVYLKSKEMQCHPKGKRMTLPDYWVLCEYEIKDPEQKAFTVENLRPESHYEFLVTPYTSAGQGPNETFTKVMTPDENSNMLLKIILPMTLCVLLIIIACYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNAHLIMNVKDCIPDVLEVINKVEGPKTQCIVSGNPHNEDVSMKPPSSVPTEDGSSGSVPFFFFENFTYDQSAFDSGSHGLIPGPLKDTPCQLGLLTPPEKLLNVLEKDYMKSLAESPTEETSLIYVSQLASPMGGDKDSLATNPPMPGHCSEYKMQMAVPGRLPSLALSENNSLTSEILLGQGEQ", "length": 984 }, "evidence": [ { "id": "A0A8V0YLX6", "url": "https://omabrowser.org/oma/group/A0A8V0YLX6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SN77-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "OSMR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALYTVFPTVFLLALLSLSTYQSKVLSKPLPLTPESLKVSINSAHQCLHLQWMVHSLAYHQELKMVFQIQISRFTTSNVIWTESYSTTVKGNQVLRWSWESELPLECATHFVRVRSMVDDARIPEPKFWSNWSRWEEADAQNSLGQDLLFLFPKDKLVEEGSDVTICYTSRNPQHNISCYLEGAQIHGKQLDPRVSAFELKNVSFIRRTGTNIFCEDPGVAMKGTVLFVSKILEEPKDFSCETQDFKNLNCTWDPGSDTALPKQPSQSYTLFESFSGKKILCEHRNFCNWQVAQDSQEMYNFTLVAENYLRKRSVNILFNLTHRVHPMIPYNLFFKNISATNATVTWKVHSAGNDSTLLCQLELFGEGKVIQQQNVSVKVNGEYLFNELEPDTKYVAQVRCAYADHFWKWSEPISQKFNTPEAAPSEALDVWRNVRLVSGHPTVNLFWKPLSKSHANGKILFYKVFVENLDNPSGLEDLSIPAPANSTELPLDRGSYQIHVTAHNSVGASPASVIVISGDSENREVEEGRVNGTEDGFSMSWKPQARDTVGYIVEWCDRPQDLPCDPQWKNVGPNTTSTVISSDTFRPGVRYNFRIYGISTDWTAHLLERKTGYVEELAPSDNPRVVTSNLTSHSFTLSWKDYSTESQPGFIQGYYLYLKSKAGEQCLPGFKKTGLLTGDSVCCKHRIDDPEQKTFVVENLQPESIYEFLVTPYTSAGEGPLGAFTKVTTPDEYSHILIRILLPMIFCVLLIMIVCYLKSQWLKEKCYPDIPDPYKSSVLSVIKSKENPHLTIMNVNDCVPDAIEVLNKPEGSKKQFVDARKSLTEAEFTKPTYLYLLPTEKNYPGSGPCICFENFTYNQAASGSGSCGPFPVTPQVPPGQPGPLTSPGNLLKALEKNYMSSLGEIPAGEASLNYVSQLASPMSGDKDNLPTNPPEPALCSEYKMQMAIPLGLASPPPSEKSRLSSPTFLDQGEHHR", "length": 977 }, "evidence": [ { "id": "A0A8V0YLX6", "url": "https://omabrowser.org/oma/group/A0A8V0YLX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O70458-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "Osmr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"evidence": [ { "id": "A0A8V0YLX6", "url": "https://omabrowser.org/oma/group/A0A8V0YLX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q65Z14-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "Osmr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFSVVLHQVTFLLAVLSLRTSQSKVLGEPLQLTPEIHTVSLQSALQEANLEWTVPTFSHQELNIVFQIEISRMRTSNTIWVGNYSTTVKHEETVHWKWTSDIPLECATHFIRIRAMVDDAQYPPQSSWSNWSSWKEVNAQVSVPPDTLLIFPEDRLLEEGSNVTICLMIGQNLYNVSCKLQEEPIRGEQLDSHLSLIKLNNVVFLNNAGTNINCKAMNGTKNTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGIDTTLSWHKQRSQHYTLYESFSGRREVSNHRNSHTWQITEDSQETYNFTLTAENNLRKRSVSISFNLTHRVHPKAPHDVTLKTVGATKAHMTWKVPSRGDYTLLCQVELQCEGEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASANHFWKWSDWMQKKFRTPEAAPSEALDVWRDVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHEEVHEKTIKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFERSVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAGQGPNETYTKVTTPDVRSHMLLQIILPMTLGVFLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHTEDVPTKPPLVPTEKDSSGPMPFVFLENFTYDQSAFDSGSHGFIPGPLKNTPHQLGLLAPPNKLQNVLENDYMKSLVESPTEETSLIYVSQLASPICGDKDSLVTNPPMPVHGSEYKKQMALPGSLTSASLKENNLTS", "length": 962 }, "evidence": [ { "id": "A0A8V0YLX6", "url": "https://omabrowser.org/oma/group/A0A8V0YLX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99650-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "OSMR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKSSILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYLLPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC", "length": 979 }, "evidence": [ { "id": "A0A8V0YLX6", "url": "https://omabrowser.org/oma/group/A0A8V0YLX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "oncostatin-M receptor complex", "id": "GO:0005900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "oncostatin-M receptor activity", "id": "GO:0004924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX6" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": 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"end_pos": 832 }, { "start_pos": 837, "end_pos": 839 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLY7-1", "uniprot_ac": "A0A8V0YLY7", "uniprot_id": "A0A8V0YLY7_CHICK", "mass": { "chemical_mass": 52217.0, "monoisotopic_mass": 52217.0 }, "refseq": { "ac": "NP_990073", "name": "E3 ubiquitin-protein ligase makorin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" }, "gene_names": [ { "name": "MKRN4P", "type": "recommended", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "name": "MKRN1", "type": "synonym", "evidence": [ { "id": "NP_990073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] }, { "name": "MKRN4P", "type": "synonym", "evidence": [ { "id": "NP_990073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase makorin-1", "type": "synonym", "evidence": [ { "id": "NP_990073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] }, { "name": "RING-type E3 ubiquitin transferase makorin-1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7/entry#names_and_taxonomy" } ] }, { "name": "makorin 1", "type": "synonym", "evidence": [ { "id": "NP_990073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] }, { "name": "makorin ring finger protein 1", "type": "synonym", "evidence": [ { "id": "NP_990073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF192787.1, SRR13267659.178792.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_990073.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MKRN4P", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7", "locus": { "chromosome": "1", "start_pos": 56822899, "end_pos": 56847055, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013348", "url": "https://www.ensembl.org/id/ENSGALG00010013348" } ] } } ], "crossref": [ { "id": "A0A8V0YLY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395500", "url": "https://www.ncbi.nlm.nih.gov/gene/395500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395500", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YLY7", "url": "https://www.orthodb.org/?gene=A0A8V0YLY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRW1", "url": "https://www.orthodb.org/?gene=A0A8V0YRW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11224:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11224:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-198323", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198323", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948751", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948751", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAVALGTTADAAAAAVLGPSVAAGATGTIFGPAAVPPLALGPGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSTGQSAMVCRYYQRGCCAYGDHCRYEHTKPLMQEEELTTVNPAAKTYPSDLALLPETVEEDIIEIEDENIDLAAAGVGAEDWVNAVEFVPGQPYCGRAAPSCTEVPLEEMVIEEEYEKQEADEEMKKQLCPYAAVGECRYGENCVYIHGDVCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKPCRYFDEGRGSCPFGGNCFYKHAYPDGRQEEPQRPKAQRRNRFWEFIEERENGDPFETDEDEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDYYDLDL", "length": 464, "header": "tr|A0A8V0YLY7-1|A0A8V0YLY7_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MKRN4P PE=4 SV=1 CANONICAL=A0A8V0YLY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7/entry", "sequence": { "sequence": "MAEAVALGTTADAAAAAVLGPSVAAGATGTIFGPAAVPPLALGPGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSTGQSAMVCRYYQRGCCAYGDHCRYEHTKPLMQEEELTTVNPAAKTYPSDLALLPETVEEDIIEIEDENIDLAAAGVGAEDWVNAVEFVPGQPYCGRAAPSCTEVPLEEMVIEEEYEKQEADEEMKKQLCPYAAVGECRYGENCVYIHGDVCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKPCRYFDEGRGSCPFGGNCFYKHAYPDGRQEEPQRPKAQRRNRFWEFIEERENGDPFETDEDEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDYYDLDL", "length": 464, "header": "tr|A0A8V0YLY7-1|A0A8V0YLY7_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MKRN4P PE=4 SV=1 CANONICAL=A0A8V0YLY7-1" }, "locus": { "chromosome": "1", "start_pos": 56846988, "end_pos": 56826518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032137.1", "url": "https://www.ensembl.org/id/ENSGALT00010032137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018927.1", "url": "https://www.ensembl.org/id/ENSGALP00010018927.1" } ] } }, { "isoform_ac": "A0A8V0YRW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW1/entry", "sequence": { "sequence": "MAEAVALGTTADAAAAAVLGPSVAAGATGTIFGPAAVPPLALGPGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSTGQSAMVCRYYQRGCCAYGDHCRYEHTKPLMQEEELTTVNPAAKTYPSDLALLPETVEEDIIEIEDENIDLAAAGVGAEDWVNAVEFVPGQPYCGRAAPSCTEVPLEEMVIEEEYEKQEADEEMKKQLCPYAAVGECRYGENCVYIHGDVCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKPCRYFDEGRGSCPFGGNCFYKHAYPDGRQEEPQRPKAQRRNRFWEFIEERENGDDELTDSEDEWDLFHDELEDYYDLDL", "length": 437, "header": "tr|A0A8V0YRW1-1|A0A8V0YLY7_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MKRN4P PE=4 SV=1 CANONICAL=A0A8V0YLY7-1" }, "locus": { "chromosome": "1", "start_pos": 56846988, "end_pos": 56826518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032135.1", "url": "https://www.ensembl.org/id/ENSGALT00010032135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018925.1", "url": "https://www.ensembl.org/id/ENSGALP00010018925.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395500", "resource": "KEGG Pathway" }, { "id": "R-GGA-198323", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198323", "resource": "Reactome", "description": "AKT phosphorylates targets in the cytosol" }, { "id": "R-GGA-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8948757", "name": "AKT phosphorylates MKRN1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-976042" ], "output_participant_list": [ "R-GGA-8948758" ], "enzyme_list": [ "A0A3Q2U4X3-1", "A0A8V0YLY7-1" ], "evidence": [ { "id": "R-GGA-8948757", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948757" } ] }, { "id": "R-GGA-8948775", "name": "MKRN1 polyubiquitinates PTEN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZJ28-1", "A0A8V0YLY7-1" ], "evidence": [ { "id": "R-GGA-8948775", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948775" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-8948758", "participant_name": "phospho-MKRN4P [cytosol]", "crossref": [ { "id": "ENSGALG00010013348", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032137", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YLY7", "database": "UniProt", "url": "" }, { "id": "NP_990073.2", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010018927", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-976042", "participant_name": "MKRN4P [cytosol]", "crossref": [ { "id": "A0A8V0YLY7", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010013348", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010018927", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032137", "database": "ENSEMBL", "url": "" }, { "id": "NP_990073.2", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", 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] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", 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[] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YLZ9-1", "uniprot_ac": "A0A8V0YLZ9", "uniprot_id": "A0A8V0YLZ9_CHICK", "mass": { "chemical_mass": 23145.0, "monoisotopic_mass": 23145.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Histone H2A", "type": "recommended", "evidence": [ { "id": "A0A8V0YLZ9", "database": "UniProtKB", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10110:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-425986", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-425986", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046796937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YM21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMLCCLLSLLTLACPSAADYLDEPNLGSSLLPHYEHDHADAVGSSQDTRLQIFTVDYNNVQIPYEVTLWILLASLAKIGFHLYHRLPRLMPESCILIATGALVGAIIFGTDHKSPPVMNTSIYFLYLLPPIVLEEGYFMPTRPFFENLGSILWWSVLGSLLNSFGIGLSLYGICQIEAFGLTDLNLLQNLLFGSMISAVDPVAALAVFEEASVNEQLHMMIFGESLLNDGITVVLYNIFIAFTQMHRYEEIESIDILAGFARFFVVGLGGMLFGIVFGFVSALMTRFTHNVSAIEPLLVFMFSYLSYLCAEILYISGIMAMTACAVTMKKYVEENVCQNSYTTIKYFMKMLSSVSETLIFVFMGVSTVGKNHEWNWAFICFTLLFCLIWRTLSVFALFYISNKFRTYPLTFKDQLIISYSGLRGASSFSLAFLLPGKLFPRKKLFITATLVVIYFTVFIQGITIGPLVRYLDVKKTNKKESINEEIHMRLMDHLKAGIEDICGHWSHYQLRDKFKKFDNKYLKKILIREHQPKSSIVSLYKKMEIKLAIEMAENAMKISESSTASLQRCRNRRDHRLSPAEVESMRDVLAHNLYQVRQRAPSYNRHNLPSNTSEKQAQEILIRRQHSLRQSCRKGNSLPWGRPVNATSMRYLSLPQDHSGQPTRRKARHVTFTDHPRSSSEAGIPVKFKPQPQLRPLIAKHYQKELVPMAHLDRRDRSSHLSGRRGSAINRHHFTRADNRAAITKPRGTVRKLRGYESEEETEMMAPARPLDI", "length": 774, "header": "tr|A0A8V0YM25-1|A0A8V0YM25_CHICK Isoform 1 of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=SLC9A4 PE=3 SV=1 CANONICAL=A0A8V0YM25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM21/entry", "sequence": { "sequence": "VGSPATEHMKMLCCLLSLLTLACPSAADYLDEPNLGSSLLPHYEHDHADAVGSSQDTRLQIFTVDYNNVQIPYEVTLWILLASLAKIGFHLYHRLPRLMPESCILIATGALVGAIIFGTDHKSPPVMNTSIYFLYLLPPIVLEEGYFMPTRPFFENLGSILWWSVLGSLLNSFGIGLSLYGICQIEAFGLTDLNLLQNLLFGSMISAVDPVAALAVFEEASVNEQLHMMIFGESLLNDGITVVLYNIFIAFTQMHRYEEIESIDILAGFARFFVVGLGGMLFGIVFGFVSALMTRFTHNVSAIEPLLVFMFSYLSYLCAEILYISGIMAMTACAVTMKKYVEENVCQNSYTTIKYFMKMLSSVSETLIFVFMGVSTVGKNHEWNWAFICFTLLFCLIWRTLSVFALFYISNKFRTYPLTFKDQLIISYSGLRGASSFSLAFLLPGKLFPRKKLFITATLVVIYFTVFIQGITIGPLVRYLDVKKTNKKESINEEIHMRLMDHLKAGIEDICGHWSHYQLRDKFKKFDNKYLKKILIREHQPKSSIVSLYKKMEIKLAIEMAENAMKISESSTASLQRCRNRRDHRLSPAEVESMRDVLAHNLYQVRQRAPSYNRHNLPSNTSEKQAQEILIRRQHSLRQSCRKGNSLPWGRPVNATSMRYLSLPQDHSGQPTRRKARHVTFTALQVGRSRSDTPKVIKAP", "length": 700, "header": "tr|A0A8V0YM21-1|A0A8V0YM25_CHICK Computationally mapped isoform of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=SLC9A4 PE=3 SV=1 CANONICAL=A0A8V0YM25-1" }, "locus": { "chromosome": "1", "start_pos": 134083827, "end_pos": 134052942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033296.1", "url": "https://www.ensembl.org/id/ENSGALT00010033296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019655.1", "url": "https://www.ensembl.org/id/ENSGALP00010019655.1" } ] } }, { "isoform_ac": "A0A8V0YM25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25/entry", "sequence": { "sequence": "MKMLCCLLSLLTLACPSAADYLDEPNLGSSLLPHYEHDHADAVGSSQDTRLQIFTVDYNNVQIPYEVTLWILLASLAKIGFHLYHRLPRLMPESCILIATGALVGAIIFGTDHKSPPVMNTSIYFLYLLPPIVLEEGYFMPTRPFFENLGSILWWSVLGSLLNSFGIGLSLYGICQIEAFGLTDLNLLQNLLFGSMISAVDPVAALAVFEEASVNEQLHMMIFGESLLNDGITVVLYNIFIAFTQMHRYEEIESIDILAGFARFFVVGLGGMLFGIVFGFVSALMTRFTHNVSAIEPLLVFMFSYLSYLCAEILYISGIMAMTACAVTMKKYVEENVCQNSYTTIKYFMKMLSSVSETLIFVFMGVSTVGKNHEWNWAFICFTLLFCLIWRTLSVFALFYISNKFRTYPLTFKDQLIISYSGLRGASSFSLAFLLPGKLFPRKKLFITATLVVIYFTVFIQGITIGPLVRYLDVKKTNKKESINEEIHMRLMDHLKAGIEDICGHWSHYQLRDKFKKFDNKYLKKILIREHQPKSSIVSLYKKMEIKLAIEMAENAMKISESSTASLQRCRNRRDHRLSPAEVESMRDVLAHNLYQVRQRAPSYNRHNLPSNTSEKQAQEILIRRQHSLRQSCRKGNSLPWGRPVNATSMRYLSLPQDHSGQPTRRKARHVTFTDHPRSSSEAGIPVKFKPQPQLRPLIAKHYQKELVPMAHLDRRDRSSHLSGRRGSAINRHHFTRADNRAAITKPRGTVRKLRGYESEEETEMMAPARPLDI", "length": 774, "header": "tr|A0A8V0YM25-1|A0A8V0YM25_CHICK Isoform 1 of Sodium/hydrogen exchanger OS=Gallus gallus OX=9031 GN=SLC9A4 PE=3 SV=1 CANONICAL=A0A8V0YM25-1" }, "locus": { "chromosome": "1", "start_pos": 134084661, "end_pos": 134052966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033305.1", "url": "https://www.ensembl.org/id/ENSGALT00010033305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019660.1", "url": "https://www.ensembl.org/id/ENSGALP00010019660.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-425986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-425986", "resource": "Reactome", "description": "Sodium/Proton exchangers" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of pH", "id": "GO:0006885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "transepithelial ammonium transport", "id": "GO:0070634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" }, { "id": "PF00999", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation/H+ exchanger transmembrane", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 470, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YM25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM25" }, { "id": "PF16644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium/hydrogen exchanger regulatory region", "eco_id": "ECO_0000259", "start_pos": 562, "end_pos": 668, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 612, "end_pos": 614 }, { "start_pos": 646, "end_pos": 648 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YM26-1", "uniprot_ac": "A0A8V0YM26", "uniprot_id": "A0A8V0YM26_CHICK", "mass": { "chemical_mass": 45060.0, "monoisotopic_mass": 45060.0 }, "refseq": {}, "gene_names": [ { "name": "HSFX5", "type": "recommended", "evidence": [ { "id": "A0A8V0YM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26" } ] } ], "protein_names": [ { "name": "HSF-type DNA-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSFX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26", "locus": {} } ], "crossref": [ { "id": "A0A8V0YM26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM26", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM26", "url": "https://www.orthodb.org/?gene=A0A8V0YM26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARATFDQCETGHIEMEAFASDLEELAETSSSTSTDPAGQDQAPAGHAAGTPMLEEQGSQRFPDEEESKGLPLRSSEEGAGQASSCSPLSFPQKLWVLAESEQVKSIRWGHGGNCIVVEEERFMEEVLAKEAPVRAFGCTSVKSFVRQLNHYGFTKVPRDLERSPSLPEFLAEEEAIAAGRKVSLLLYSSPFFRRDYPWLLERCKRRAAHKRKAVAAPALQESGNESPQRSSPDVRPTQGAAAGPARNLQAAEHQGTQAASPLGPAPAKRPKNDTLRAQGGDAHILPGPAAAPALEQHQALPCSVLPPSSNHVLGATCTPPPQGTLPFVLPTFTPGHPQQELPQPPETPQLQAPWDALTFLGSCFAMAMRAAAMMMPPGWQPRAAPHCPTCTCSQHQAAPHCPTCTCSQRRADAGHGMGP", "length": 421, "header": "tr|A0A8V0YM26-1|A0A8V0YM26_CHICK Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Gallus gallus OX=9031 GN=HSFX5 PE=3 SV=1 CANONICAL=A0A8V0YM26-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26/entry", "sequence": { "sequence": "MAARATFDQCETGHIEMEAFASDLEELAETSSSTSTDPAGQDQAPAGHAAGTPMLEEQGSQRFPDEEESKGLPLRSSEEGAGQASSCSPLSFPQKLWVLAESEQVKSIRWGHGGNCIVVEEERFMEEVLAKEAPVRAFGCTSVKSFVRQLNHYGFTKVPRDLERSPSLPEFLAEEEAIAAGRKVSLLLYSSPFFRRDYPWLLERCKRRAAHKRKAVAAPALQESGNESPQRSSPDVRPTQGAAAGPARNLQAAEHQGTQAASPLGPAPAKRPKNDTLRAQGGDAHILPGPAAAPALEQHQALPCSVLPPSSNHVLGATCTPPPQGTLPFVLPTFTPGHPQQELPQPPETPQLQAPWDALTFLGSCFAMAMRAAAMMMPPGWQPRAAPHCPTCTCSQHQAAPHCPTCTCSQRRADAGHGMGP", "length": 421, "header": "tr|A0A8V0YM26-1|A0A8V0YM26_CHICK Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Gallus gallus OX=9031 GN=HSFX5 PE=3 SV=1 CANONICAL=A0A8V0YM26-1" }, "locus": { "chromosome": "1", "start_pos": 69896889, "end_pos": 69894889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032179.1", "url": "https://www.ensembl.org/id/ENSGALT00010032179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018969.1", "url": "https://www.ensembl.org/id/ENSGALP00010018969.1" } ] } } ], "glycosylation": [ { 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"site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM26" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 208, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 239 ], "snv_sites": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0YM49", "locus": { "chromosome": "1", "start_pos": 136826025, "end_pos": 136596514, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013378", "url": "https://www.ensembl.org/id/ENSGALG00010013378" } ] } } ], "crossref": [ { "id": "A0A8V0YM49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM49", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11928", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11928", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM49", "url": "https://www.orthodb.org/?gene=A0A8V0YM49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167", "url": 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], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM49" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM49" } ], "pmid": "" }, { "name": "protein 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"https://www.ncbi.nlm.nih.gov/protein/NP_001385362" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000094.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001385362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385362" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95", "locus": { "chromosome": "Z", "start_pos": 36485064, "end_pos": 36419310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015872", "url": "https://www.ensembl.org/id/ENSGALG00010015872" } ] } } ], "crossref": [ { "id": "A0A8V0YM95", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM95", "database": "AlphaFoldDB", "categories": [] }, { "id": "427255", "url": "https://www.ncbi.nlm.nih.gov/gene/427255", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM95", "url": "https://www.orthodb.org/?gene=A0A8V0YM95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTM7", "url": "https://www.orthodb.org/?gene=A0A8V0YTM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001385362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YM95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKNEKPATSEGNDGSDVNNEEDSAAENQENGRGADKERKRAKPRTRRGHARGRARHGGEEDGDDEDGTRRAGQRRQRNRRGRGRAGGNEGSDSEGDPTKARKNQANQKSKEDDEQEEDEKGGKSGKGKNEKKQDKKADKKGKKEKANKKKKDKKKSGSGSDSDSEEEPITEEELAKLKEEVEEKKKLIATLRNKPWKMKKKLSVLKEAQLFVEKFEGALGKGKGKKFYAYKVMMTKKWMKFQRDFENFKTACIPWEMKIKEIESHFGSSVASYFIFLRWMYGINMILFGLTFGLVMVPEALMGKPYGSLPRKTVPRAEEATAMNFATLWDFSGFAQYSVLFYGYYNNQRTIGWLKFRMPLSYFLVGVGTIGYSFMIVIRTMARNANEEGGGDDTSFNFSWKMFTSWDYLIGNPETADNKFASITTSFKEAIVEEQESRKEENIHLTRFLRVLANFLALCTLAGSGYLIFFVVRRSQKFALEGLENYGWWERNEVNMVMSLLGMFCPTLFDVISSLENYHPRIALRWQLGRIFALFLGNLYTFIIALMDEINLKLEEEKIVKYNMTIWEASLYNGTIPENSTAPPIQVDPADVPRGPCWETMVGQEFVRLTVSDTMTTYITILIGDFLRAVFVRFFNYCWCWDLEYGFPSYSEFDISGNVLGLIFNQGMIWMGSFYAPCLPAINVFRLHTSMYLQCWAVMCCNVPQERVFKASRSNNFYMAMLLFILFLSTLPAVYTIVSIPPSFDCGPFSGKTRMFEVISETLEHDFPSWFGKVFGYASNPGLILPFILLMVLSIYYLNATSKSYKEANLELKKKLQSQAEENKRRNKQKAQKSNEQEENPFETEPPQSKQKGGKQDESAANQDNKKEQSGNEAKTTGQPQEASASSSQKPQHPGAALNGHYPPQGRGGNLLPPPIAVTRPPGPSGYAAPGYPPGHPRFPGVQPGMPRGPPHYR", "length": 955, "header": "tr|A0A8V0YM95-1|A0A8V0YM95_CHICK Isoform 1 of Transmembrane channel-like protein OS=Gallus gallus OX=9031 GN=TMC1 PE=3 SV=1 CANONICAL=A0A8V0YM95-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95/entry", "sequence": { "sequence": "MPKNEKPATSEGNDGSDVNNEEDSAAENQENGRGADKERKRAKPRTRRGHARGRARHGGEEDGDDEDGTRRAGQRRQRNRRGRGRAGGNEGSDSEGDPTKARKNQANQKSKEDDEQEEDEKGGKSGKGKNEKKQDKKADKKGKKEKANKKKKDKKKSGSGSDSDSEEEPITEEELAKLKEEVEEKKKLIATLRNKPWKMKKKLSVLKEAQLFVEKFEGALGKGKGKKFYAYKVMMTKKWMKFQRDFENFKTACIPWEMKIKEIESHFGSSVASYFIFLRWMYGINMILFGLTFGLVMVPEALMGKPYGSLPRKTVPRAEEATAMNFATLWDFSGFAQYSVLFYGYYNNQRTIGWLKFRMPLSYFLVGVGTIGYSFMIVIRTMARNANEEGGGDDTSFNFSWKMFTSWDYLIGNPETADNKFASITTSFKEAIVEEQESRKEENIHLTRFLRVLANFLALCTLAGSGYLIFFVVRRSQKFALEGLENYGWWERNEVNMVMSLLGMFCPTLFDVISSLENYHPRIALRWQLGRIFALFLGNLYTFIIALMDEINLKLEEEKIVKYNMTIWEASLYNGTIPENSTAPPIQVDPADVPRGPCWETMVGQEFVRLTVSDTMTTYITILIGDFLRAVFVRFFNYCWCWDLEYGFPSYSEFDISGNVLGLIFNQGMIWMGSFYAPCLPAINVFRLHTSMYLQCWAVMCCNVPQERVFKASRSNNFYMAMLLFILFLSTLPAVYTIVSIPPSFDCGPFSGKTRMFEVISETLEHDFPSWFGKVFGYASNPGLILPFILLMVLSIYYLNATSKSYKEANLELKKKLQSQAEENKRRNKQKAQKSNEQEENPFETEPPQSKQKGGKQDESAANQDNKKEQSGNEAKTTGQPQEASASSSQKPQHPGAALNGHYPPQGRGGNLLPPPIAVTRPPGPSGYAAPGYPPGHPRFPGVQPGMPRGPPHYR", "length": 955, "header": "tr|A0A8V0YM95-1|A0A8V0YM95_CHICK Isoform 1 of Transmembrane channel-like protein OS=Gallus gallus OX=9031 GN=TMC1 PE=3 SV=1 CANONICAL=A0A8V0YM95-1" }, "locus": { "chromosome": "Z", "start_pos": 36484060, "end_pos": 36427189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038276.1", "url": "https://www.ensembl.org/id/ENSGALT00010038276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022098.1", "url": "https://www.ensembl.org/id/ENSGALP00010022098.1" } ] } }, { "isoform_ac": "A0A8V0YTM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM7/entry", "sequence": { "sequence": "MAVLELSLLMHVKLFSKDLALINDNTVLRFLGKNGSDVNNEEDSAAENQENGRGADKERKRAKPRTRRGHARGRARHGGEEDGDDEDGTRRAGQRRQRNRRGRGRAGGNEGSDSEGDPTKARKNQANQKSKEDDEQEEDEKGGKSGKGKNEKKQDKKADKKGKKEKANKKKKDKKKSGSGSDSDSEEEPITEEELAKLKEEVEEKKKLIATLRNKPWKMKKKLSVLKYEAQLFVEKFEGALGKGKGKKFYAYKVMMTKKWMKFQRDFENFKTACIPWEMKIKEIESHFGSSVASYFIFLRWMYGINMILFGLTFGLVMVPEALMGKPYGSLPRKTVPRAEEATAMNFATLWDFSGFAQYSVLFYGYYNNQRTIGWLKFRMPLSYFLVGVGTIGYSFMIVIRTMARNANEEGGGDDTSFNFSWKMFTSWDYLIGNPETADNKFASITTSFKEAIVEEQESRKEENIHLTRFLRVLANFLALCTLAGSGYLIFFVVRRSQKFALEGLENYGWWERNEVNMVMSLLGMFCPTLFDVISSLENYHPRIALRWQLGRIFALFLGNLYTFIIALMDEINLKAKRIKNWYLYNGTIPENSTAPPIQVDPADVPRGPCWETMVGQEFVRLTVSDTMTTYITILIGDFLRAVFVRFFNYCWCWDLEYGFPSYSEFDISGNVLGLIFNQGMIWMGSFYAPCLPAINVFRLHTSMYLQCWAVMCCNVPQERVFKASRSNNFYMAMLLFILFLSTLPAVYTIVSIPPSFDCGPFSGKTRMFEVISETLEHDFPSWFGKVFGYASNPGLILPFILLMVLSIYYLNATSKSYKEANLELKKKLQSCILKPKRKMKIRDDHLWKSCM", "length": 852, "header": "tr|A0A8V0YTM7-1|A0A8V0YM95_CHICK Computationally mapped isoform of Transmembrane channel-like protein OS=Gallus gallus OX=9031 GN=TMC1 PE=3 SV=1 CANONICAL=A0A8V0YM95-1" }, "locus": { "chromosome": "Z", "start_pos": 36480303, "end_pos": 36420798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038266.1", "url": "https://www.ensembl.org/id/ENSGALT00010038266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022090.1", "url": "https://www.ensembl.org/id/ENSGALP00010022090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vestibular reflex", "id": "GO:0060005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM95" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": 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{ "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ] } ], "protein_names": [ { "name": "Phospholipase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7", "locus": { "chromosome": "9", "start_pos": 19258207, "end_pos": 19198902, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014093", "url": "https://www.ensembl.org/id/ENSGALG00010014093" } ] } } ], "crossref": [ { "id": "A0A8V0YMC7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009252", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009252", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01254", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01254", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07296", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07296", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09842", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09842", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09844", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09844", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424986", "url": "https://www.ncbi.nlm.nih.gov/gene/424986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC7", "url": "https://www.orthodb.org/?gene=A0A8V0YMC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ0", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPG5", "url": "https://www.orthodb.org/?gene=A0A8V0YPG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUI0", "url": "https://www.orthodb.org/?gene=A0A8V0YUI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVP2", "url": "https://www.orthodb.org/?gene=E1BVP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18896:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18896:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14445", "url": "https://www.rhea-db.org/rhea/14445", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVP2", "url": "https://www.uniprot.org/uniprotkb/E1BVP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVP2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFVQHQPCGVWVLPSCQAPRGSNVRRSEMSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKGTACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMEGLVMKRSGGHRIPGLNCCGQGRMCYRWSKRWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1066, "header": "tr|A0A8V0YMC7-1|A0A8V0YMC7_CHICK Isoform 1 of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=1 CANONICAL=A0A8V0YMC7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7/entry", "sequence": { "sequence": "MGFVQHQPCGVWVLPSCQAPRGSNVRRSEMSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKGTACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMEGLVMKRSGGHRIPGLNCCGQGRMCYRWSKRWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1066, "header": "tr|A0A8V0YMC7-1|A0A8V0YMC7_CHICK Isoform 1 of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=1 CANONICAL=A0A8V0YMC7-1" }, "locus": { "chromosome": "9", "start_pos": 19257203, "end_pos": 19228774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033825.1", "url": "https://www.ensembl.org/id/ENSGALT00010033825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019898.1", "url": "https://www.ensembl.org/id/ENSGALP00010019898.1" } ] } }, { "isoform_ac": "A0A8V0YMQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ0/entry", "sequence": { "sequence": "MSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKGTGCVLLAACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMEGLVMKRSGGHRIPGLNCCGQGRMCYRWSKRWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1043, "header": "tr|A0A8V0YMQ0-1|A0A8V0YMQ0_CHICK Computationally mapped isoform of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=1 CANONICAL=A0A8V0YMC7-1" }, "locus": { "chromosome": "9", "start_pos": 19257203, "end_pos": 19229724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033843.1", "url": "https://www.ensembl.org/id/ENSGALT00010033843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019906.1", "url": "https://www.ensembl.org/id/ENSGALP00010019906.1" } ] } }, { "isoform_ac": "A0A8V0YPG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG5/entry", "sequence": { "sequence": "MSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKGTACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1006, "header": "tr|A0A8V0YPG5-1|A0A8V0YPG5_CHICK Computationally mapped isoform of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=1 CANONICAL=A0A8V0YMC7-1" }, "locus": { "chromosome": "9", "start_pos": 19257203, "end_pos": 19229724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033831.1", "url": "https://www.ensembl.org/id/ENSGALT00010033831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019902.1", "url": "https://www.ensembl.org/id/ENSGALP00010019902.1" } ] } }, { "isoform_ac": "A0A8V0YUI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI0/entry", "sequence": { "sequence": "MSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMEGLVMKRSGGHRIPGLNCCGQGRMCYRWSKRWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1035, "header": "tr|A0A8V0YUI0-1|A0A8V0YMC7_CHICK Computationally mapped isoform of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=1 CANONICAL=A0A8V0YMC7-1" }, "locus": { "chromosome": "9", "start_pos": 19257203, "end_pos": 19229724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033856.1", "url": "https://www.ensembl.org/id/ENSGALT00010033856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019910.1", "url": "https://www.ensembl.org/id/ENSGALP00010019910.1" } ] } }, { "isoform_ac": "E1BVP2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVP2/entry", "sequence": { "sequence": "MSLKHEGHAAASALKRIAADMSNIIESLDTRELHVDGEEVDSEVLSDPKGTACIPFSAIYHTRGFKEPGTQTYLTGCPVRVRVLEVERFTSTKKVPSLNVYTIELTHGEFTWHVKRKFRHFQEFHRELLRYKAFVRIPIPTRSHTVRRQSIKRGEPRQMPSLPHTAESTVREEHFSSRRKQLEDYLSKILKMPMYRNYHGTMEFIGVSQLSFIHDLGPKGMEGLVMKRSGGHRIPGLNCCGQGRMCYRWSKRWLVVKDSFLLYMKPDSGAISFVLLVDKEFSIKIGQKETETKYGLQIDNLSRSLILKCTSYRHAQWWRQGIDEFIRKHGKDFLTEHRFGSYAAVQENTLAKWYVNAKWYFEDVANAMEAAKEEIFITDWWLSPEIFMKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSEYSKRTLMHLHPNIKVMRHPDHVSSSVYLWAHHEKLVIVDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRMGAVKSVSTANLASAAEPSGHNTPQSPASSPESHLFQKSADDVPDISKMKGIGKPRKFSRFTIYKHLHRHGMHHADSVSSIDSESNKGSIRSLKTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYTTPRMPWHDISSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQQTANELKYQVPDAVHATVQVIRSAADWSAGIKYHEESIHAAYVSVIENSKHYIYIENQFFISCADDKVVWNKIGDAIAQRILKAHRENKRYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILSQLKPEVGDKWINYISFCGLRTYAELEGKLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEIAIIVQDTETVPSVMDGEAYSAGRFAQSLRLRCFRVVLGGSDLNPDHQDPVCERFFKEVWISTAARNATIFDKVFRCLPSDQVNNLAQLRDFINKPILANDDPVKAAEELKKIRGFLVQFPFRFLEEEYLLPSVGTKESMVPMEVWT", "length": 1037, "header": "tr|E1BVP2-1|A0A8V0YMC7_CHICK Computationally mapped isoform of Phospholipase OS=Gallus gallus OX=9031 GN=PLD1 PE=1 SV=2 CANONICAL=A0A8V0YMC7-1" }, "locus": { "chromosome": "9", "start_pos": 19257203, "end_pos": 19229724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033869.1", "url": "https://www.ensembl.org/id/ENSGALT00010033869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019918.1", "url": "https://www.ensembl.org/id/ENSGALP00010019918.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cellular response to nutrient", "id": "GO:0031670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "regulation of vesicle-mediated transport", "id": "GO:0060627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle cycle", "id": "GO:0098693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipase D activity", "id": "GO:0004630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" }, { "name": "cholinergic synapse", "id": "GO:0098981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14445", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMC7-1", "A0A8V0Y5K1-1" ], "evidence": [ { "id": "14445", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14445" } ] }, { "id": "R-GGA-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-1483182", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483182" } ] }, { "id": "R-GGA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, tertiary granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "P15120-1", "Q5F352-1", "A0A8V0ZZE4-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6798747", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798747" } ] }, { "id": "R-GGA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "A0A3Q2U2N5-1", "A0A8V1AKE3-1", "P15120-1", "A0A1D5P3W4-1", "Q5F3C1-1", "A0A8V1AN75-1", "A0A8V0ZZE4-1", "F1NSA8-1", "A0A8V0YXK7-1", "A0A8V0Y5N7-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799350" } ] }, { "id": "R-GGA-9013009", "name": "RHOA binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BQV7-1", "A0A3Q3B2F1-1", "A0A8V0XE48-1", "A0A8V0ZSP4-1", "A0A8V0Z9J0-1", "A0A8V0YXK7-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-9013009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013009" } ] }, { "id": "R-GGA-9013145", "name": "RAC1 binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "A0A8V0ZSP4-1", "E1C3P6-1", "A0A3Q2TRY2-1", "A0A8V0ZUC6-1", "A0A8V0YXZ5-1", "A0A8V0Z9J0-1", "A0A8V0YZF2-1", "A0A8V0YYX2-1", "A0A8V0Z8U4-1", "Q90694-1", "A0A8V0Y7Y3-1", "A0A8V0Y955-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-9013145", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013145" } ] }, { "id": "R-GGA-9014449", "name": "RHOG binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "Q90694-1", "A0A8V0Y955-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-9014449", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014449" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2U2N5", "gene_name": "ATP8A1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": 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Computationally mapped isoform of RAB6-interacting golgin OS=Gallus gallus OX=9031 GN=GORAB PE=1 SV=2 CANONICAL=A0A8V0YMR8-1" }, "locus": { "chromosome": "8", "start_pos": 4897697, "end_pos": 4890083, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033879.1", "url": "https://www.ensembl.org/id/ENSGALT00010033879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019924.1", "url": "https://www.ensembl.org/id/ENSGALP00010019924.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": 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May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGVGAARRSWAAAVVVLLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVKISDEDRKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEEVRINELQIEARDKGFPPLSGHCSVELEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPA", "length": 825, "header": "tr|A0A8V0YMH8-1|A0A8V0YMH8_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YMH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8/entry", "sequence": { "sequence": "MVGVGAARRSWAAAVVVLLQAAWALVGGQVRYSVPEEAEAGTVVGRLAQDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVKISDEDRKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEEVRINELQIEARDKGFPPLSGHCSVELEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGAGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAPALLPPAGGGPWPWAAGEAAEPGSRPPGSAGSAVSSWSLWARAAWGAPAGQVVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVVRDHGEPPRSATATLSVSLVEGAEAAVGAVSVSAGAGLRPAASAEGGSAASGASAATNVWLVVAICAVSSLLVLAVVLYGAGRWAPRAAVLAGPGPATLVCASEVGSWSYSQRQSRSLCVATDGAGKSDLMVFSPNCPPAPGPA", "length": 825, "header": "tr|A0A8V0YMH8-1|A0A8V0YMH8_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YMH8-1" }, "locus": { "chromosome": "13", "start_pos": 932942, "end_pos": 930468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029738.1", "url": "https://www.ensembl.org/id/ENSGALT00010029738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017313.1", "url": "https://www.ensembl.org/id/ENSGALP00010017313.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH8" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 132, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 557, "end_pos": 559 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMI3-1", "uniprot_ac": "A0A8V0YMI3", "uniprot_id": "A0A8V0YMI3_CHICK", "mass": { "chemical_mass": 22192.0, "monoisotopic_mass": 22192.0 }, "refseq": { "ac": "XP_015132926", "name": "interferon type A3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132926" }, "gene_names": [ { "name": "LOC768614", "type": "recommended", "evidence": [ { "id": "A0A8V0YMI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3" } ] }, { "name": "LOC768614", "type": "synonym", "evidence": [ { "id": "XP_015132926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132926" } ] } ], "protein_names": [ { "name": "Interferon alpha", "type": "recommended", "evidence": [ { "id": "A0A8V0YMI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3/entry#names_and_taxonomy" } ] }, { "name": "interferon type A3", "type": "synonym", "evidence": [ { "id": "XP_015132926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132926" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015132926.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132926" } ] }, { "annotation": "Has antiviral activities.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3#function" }, { "database": "UniProtKB", "id": "ARBA00002718", "url": "https://www.uniprot.org/uniprotkb/ARBA00002718#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC768614", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768614", "url": "https://www.ncbi.nlm.nih.gov/gene/768614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768614", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACLWQVM", "url": "https://omabrowser.org/oma/group/ACLWQVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMI3", "url": "https://www.orthodb.org/?gene=A0A8V0YMI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-909733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912694", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015132926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPASPQHPRGYGILLLTLLLKALATTASACNHLRPQDATFSHDSLQLFRDMAPTLLQLCPQHNASCSFNDTILDTSNTRQADKTTHDILQHLFKILSSPSTPAHWNDSQRQSLLNRIHRYTQHLEQCLDSRDTLSRTRWPRNLHLTIKKHFSCLHTFLQDNDYSACAWEHVRLQARAWFLHIHNLTGNTRT", "length": 193, "header": "tr|A0A8V0YMI3-1|A0A8V0YMI3_CHICK Isoform 1 of Interferon alpha OS=Gallus gallus OX=9031 GN=LOC768614 PE=3 SV=1 CANONICAL=A0A8V0YMI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI3/entry", "sequence": { "sequence": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMQ6-1", "uniprot_ac": "A0A8V0YMQ6", "uniprot_id": "A0A8V0YMQ6_CHICK", "mass": { "chemical_mass": 57952.0, "monoisotopic_mass": 57952.0 }, "refseq": {}, "gene_names": [ { "name": "MFSD10", "type": "recommended", "evidence": [ { "id": "A0A8V0YMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0YMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable organic anion transporter which may serve as a transporter for some non-steroidal anti-inflammatory drugs (NSAIDs) as well as other organic anions across the luminal membranes of renal proximal tubules at the final excretion step into the urine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ1#function" }, { "database": "UniProtKB", "id": "ARBA00058620", "url": "https://www.uniprot.org/uniprotkb/ARBA00058620#function" }, { "database": "UniProtKB", "id": "A0A8V0YW44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW44#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422881", "url": "https://www.ncbi.nlm.nih.gov/gene/422881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU56", "url": "https://www.orthodb.org/?gene=A0A8V0YU56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUI2", "url": "https://www.orthodb.org/?gene=A0A8V0YUI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW38", "url": "https://www.orthodb.org/?gene=A0A8V0YW38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW44", "url": "https://www.orthodb.org/?gene=A0A8V0YW44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0W3", "url": "https://www.orthodb.org/?gene=A0A8V0Z0W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0W3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIKPGNEIRVVKRAVLLLIPAFLLIGWAANVTLLSAGLLLYSFVCFVDFSSCCHCYPVFVCSGIRLRFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 530, "header": "tr|A0A8V0YMQ6-1|A0A8V0YMQ6_CHICK Isoform 1 of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ1/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIKPGNEIRVVKRAVLLLIPAFLLIGWAANVTLLSAGLLLYSFAAAIVIPCLSAVVSGYGSASQKGRVMGILRSLGALARALGPVLSATGSKLLGGKRQTSDYSKTKMAEQLQSTARVLPFPPTPSIRFMHI", "length": 469, "header": "tr|A0A8V0YMQ1-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81802658, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038478.1", "url": "https://www.ensembl.org/id/ENSGALT00010038478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022259.1", "url": "https://www.ensembl.org/id/ENSGALP00010022259.1" } ] } }, { "isoform_ac": "A0A8V0YMQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIKPGNEIRVVKRAVLLLIPAFLLIGWAANVTLLSAGLLLYSFVCFVDFSSCCHCYPVFVCSGIRLRFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 530, "header": "tr|A0A8V0YMQ6-1|A0A8V0YMQ6_CHICK Isoform 1 of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81803346, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038483.1", "url": "https://www.ensembl.org/id/ENSGALT00010038483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022264.1", "url": "https://www.ensembl.org/id/ENSGALP00010022264.1" } ] } }, { "isoform_ac": "A0A8V0YU56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU56/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIKPGNEIRVVKRAVLLLIPAFLLIGWAANVTLLSAGLLLYSFAAAIVIPCLSAVFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 518, "header": "tr|A0A8V0YU56-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81803346, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038492.1", "url": "https://www.ensembl.org/id/ENSGALT00010038492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022271.1", "url": "https://www.ensembl.org/id/ENSGALP00010022271.1" } ] } }, { "isoform_ac": "A0A8V0YUI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUI2/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQSRFVVDSSIPVNWMGCKCDPAERWTVAVLFRCCHCYPVFVCSGIRLRFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 449, "header": "tr|A0A8V0YUI2-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81803346, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038489.1", "url": "https://www.ensembl.org/id/ENSGALT00010038489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022268.1", "url": "https://www.ensembl.org/id/ENSGALP00010022268.1" } ] } }, { "isoform_ac": "A0A8V0YW38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW38/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTELSVLQDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSIPVNWMGCKCDPAERWTVAVLFRCCHCYPVFVCSGIRLRFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 484, "header": "tr|A0A8V0YW38-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81803346, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038481.1", "url": "https://www.ensembl.org/id/ENSGALT00010038481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022262.1", "url": "https://www.ensembl.org/id/ENSGALP00010022262.1" } ] } }, { "isoform_ac": "A0A8V0YW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW44/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIKPGNEIRVVKRAVLLLIPAFLLIGWAANVTLLSAGLLLYSFAAAIVIPCLSAVVSGYGSASQKGRVMGILRSLGALARALGPVLSATGEWGCVLQPTHTVTVGACSQAGAEGSVGGEPPHLFHAVCPSLNSDLS", "length": 473, "header": "tr|A0A8V0YW44-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81802470, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038487.1", "url": "https://www.ensembl.org/id/ENSGALT00010038487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022267.1", "url": "https://www.ensembl.org/id/ENSGALP00010022267.1" } ] } }, { "isoform_ac": "A0A8V0Z0W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0W3/entry", "sequence": { "sequence": "MALREGEASSSSADDKQEQNCSRVITIVFLALLIDLLGFALILPLFPSILDYYSQTEDGLYLSLQRGVDWFAAMVGMPPERKYNSVLFGGLIGSMFSILQFFSSPLTGAVSDCLGRRPVILMTAMGLIASYALWAASRSFGVFLLSRMVGGISKGNVSLCTAIIADLHSPKARSKGMAMIGVAFSLGFTLGPMIGAYLAMETEKGEVFYLRSALLALTFAAADLIFIFFLLPETLPKEKRVSSVTTGFQAAADLLSPMALFRFSAVTQGKEAPSDQNLQNLKILGLAYFLYLFLFSGLEYTLSFLTHQRFQFSSCCHCYPVFVCSGIRLRFGQPKRKSDGDPEEPRGSCEGAGTCPVSYSVLAGRGRELLHHLWSFFPHPFHFTRFYQTADEGGVGRGRKKPELSPAAKDLPTTQFSPSESTDQTGRRGCSGRRGAMTMCSNSGLQISCGLHKHFS", "length": 456, "header": "tr|A0A8V0Z0W3-1|A0A8V0YMQ6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 10 OS=Gallus gallus OX=9031 GN=MFSD10 PE=1 SV=1 CANONICAL=A0A8V0YMQ6-1" }, "locus": { "chromosome": "4", "start_pos": 81803346, "end_pos": 81782587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038491.1", "url": "https://www.ensembl.org/id/ENSGALT00010038491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022270.1", "url": "https://www.ensembl.org/id/ENSGALP00010022270.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ6" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 530, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMR6-1", "uniprot_ac": "A0A8V0YMR6", "uniprot_id": "A0A8V0YMR6_CHICK", "mass": { "chemical_mass": 86225.0, "monoisotopic_mass": 86225.0 }, "refseq": { "ac": "XP_004950191", "name": "protocadherin beta-15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950191" }, "gene_names": [ { "name": "LOC430496", "type": "recommended", "evidence": [ { "id": "A0A8V0YMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" } ] }, { "name": "LOC430496", "type": "synonym", "evidence": [ { "id": "XP_004950191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950191" } ] } ], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6/entry#names_and_taxonomy" } ] }, { "name": "protocadherin beta-15", "type": "synonym", "evidence": [ { "id": "XP_004950191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950191" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004950191.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004950191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950191" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC430496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMR6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430496", "url": "https://www.ncbi.nlm.nih.gov/gene/430496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430496", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ESHEMSV", "url": "https://omabrowser.org/oma/group/ESHEMSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF118", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF118", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004950191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARQVLCLWALLGVPRVRCEPIRYSVAEEGESGSVVADVAEDAGLAPAQLSARRARIASPAGRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPETSDPGSRFPVGAAQDLDIGSNDIQAYSIIPENEYFTVFIQSENEKFIELVLEKPLDREEQPEMDFTLVATDGGSPPRTGSTQIHIVVLDINDNAPIFTQKLYIGHVLENAPEGSVVLRVVANDADEGFNGDISYQFSQSVGHRHSLFTINSKTGEIGIAKPLDFETEKKHKLTVQAVDGGGLSSMCNVIVEVLDVNDNAPEIVVSSFNSPLPENVEPGTVIALFAVRDQDSGVNGEITCALEEQLSFSLRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPAFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQLLRATEPGLFAVGAQSGEVRLRRPPTERDAAKQKLVVLVRDNGRPPLSATAALSVLLVPGSWDAQLPQQSPAAGEDDGSLTTSLIIALVFVSLLFLLSAAAFVACKVCKRKELSSGPVLYGASSVQSYVADGAAAGTLPHAYCYEVSLTTGSGNSEFKFLKPVLPSLPAQHCSTGVGGAHAEEFPPVPVTMGDADFESPGMQSVAQLNGF", "length": 809, "header": "tr|A0A8V0YMR6-1|A0A8V0YMR6_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430496 PE=4 SV=1 CANONICAL=A0A8V0YMR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6/entry", "sequence": { "sequence": "MAAARQVLCLWALLGVPRVRCEPIRYSVAEEGESGSVVADVAEDAGLAPAQLSARRARIASPAGRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPETSDPGSRFPVGAAQDLDIGSNDIQAYSIIPENEYFTVFIQSENEKFIELVLEKPLDREEQPEMDFTLVATDGGSPPRTGSTQIHIVVLDINDNAPIFTQKLYIGHVLENAPEGSVVLRVVANDADEGFNGDISYQFSQSVGHRHSLFTINSKTGEIGIAKPLDFETEKKHKLTVQAVDGGGLSSMCNVIVEVLDVNDNAPEIVVSSFNSPLPENVEPGTVIALFAVRDQDSGVNGEITCALEEQLSFSLRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPAFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQLLRATEPGLFAVGAQSGEVRLRRPPTERDAAKQKLVVLVRDNGRPPLSATAALSVLLVPGSWDAQLPQQSPAAGEDDGSLTTSLIIALVFVSLLFLLSAAAFVACKVCKRKELSSGPVLYGASSVQSYVADGAAAGTLPHAYCYEVSLTTGSGNSEFKFLKPVLPSLPAQHCSTGVGGAHAEEFPPVPVTMGDADFESPGMQSVAQLNGF", "length": 809, "header": "tr|A0A8V0YMR6-1|A0A8V0YMR6_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430496 PE=4 SV=1 CANONICAL=A0A8V0YMR6-1" }, "locus": { "chromosome": "13", "start_pos": 1295255, "end_pos": 1292829, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029917.1", "url": "https://www.ensembl.org/id/ENSGALT00010029917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017412.1", "url": "https://www.ensembl.org/id/ENSGALP00010017412.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430496", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430496", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR6" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 126, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 445, "end_pos": 447 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMS3-1", "uniprot_ac": "A0A8V0YMS3", "uniprot_id": "A0A8V0YMS3_CHICK", "mass": { "chemical_mass": 38528.0, "monoisotopic_mass": 38528.0 }, "refseq": { "ac": "NP_996789", "name": "annexin A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" }, "gene_names": [ { "name": "ANXA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3" } ] }, { "name": "ANXA1", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "Anx1", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "p35", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A8V0YMS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3/entry#names_and_taxonomy" } ] }, { "name": "annexin A1", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "annexin I", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "annexin-1", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "calcium-dependent membrane binding protein annexin I", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "calpactin II", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "calpactin-2", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "chromobindin-9", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "lipocortin I", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] }, { "name": "phospholipase A2 inhibitory protein", "type": "synonym", "evidence": [ { "id": "NP_996789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000887.1, BX933725.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000094.1. On or before Dec 15, 2021 this sequence version replaced XP_015135755.2, NP_996789.1.", "evidence": [ { "database": "RefSeq", "id": "NP_996789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANXA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3", "locus": { "chromosome": "Z", "start_pos": 36653087, "end_pos": 36635449, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014114", "url": "https://www.ensembl.org/id/ENSGALG00010014114" } ] } } ], "crossref": [ { "id": "A0A8V0YMS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "404271", "url": "https://www.ncbi.nlm.nih.gov/gene/404271", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:404271", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404271", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMENQEQ", "url": "https://omabrowser.org/oma/group/FMENQEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS3", "url": "https://www.orthodb.org/?gene=A0A8V0YMS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_996789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMVSEFLKQAWFMDNQEQECIKSSKGGSSVQSRPNFDPSADVSALDKAITVKGVDEATIIDILTKRTNAQRQQIKAAYQQAKGKSLEEDLKKVLKSHLEDVVVALLKTPAQFDAEELRASMKGLGTDEDTLIEILASRNNREIREASRYYREVLKKDLTQDIISDTSGDFQKALVILAKGDRCEDPHVNDDLADNDARALYEAGEKRKGTDVNVFITILTSRSYPHLRRVFQKYAKYSKHDMNKVLDLELKGDIENCLTALVKCATSKPAFFAEKLHLAMKGSGTRHKQLIRIMVSRHEIDLNEIKAYYKSLYGISLRQAIMDELKGDYETILVALCGSDK", "length": 342, "header": "tr|A0A8V0YMS3-1|A0A8V0YMS3_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA1 PE=1 SV=1 CANONICAL=A0A8V0YMS3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS3/entry", "sequence": { "sequence": "MAMVSEFLKQAWFMDNQEQECIKSSKGGSSVQSRPNFDPSADVSALDKAITVKGVDEATIIDILTKRTNAQRQQIKAAYQQAKGKSLEEDLKKVLKSHLEDVVVALLKTPAQFDAEELRASMKGLGTDEDTLIEILASRNNREIREASRYYREVLKKDLTQDIISDTSGDFQKALVILAKGDRCEDPHVNDDLADNDARALYEAGEKRKGTDVNVFITILTSRSYPHLRRVFQKYAKYSKHDMNKVLDLELKGDIENCLTALVKCATSKPAFFAEKLHLAMKGSGTRHKQLIRIMVSRHEIDLNEIKAYYKSLYGISLRQAIMDELKGDYETILVALCGSDK", "length": 342, "header": "tr|A0A8V0YMS3-1|A0A8V0YMS3_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA1 PE=1 SV=1 CANONICAL=A0A8V0YMS3-1" }, "locus": { "chromosome": "Z", "start_pos": 36652748, "end_pos": 36638999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033899.1", "url": "https://www.ensembl.org/id/ENSGALT00010033899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019931.1", "url": "https://www.ensembl.org/id/ENSGALP00010019931.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:404271", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404271", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N650-1", "protein_name": "Annexin", "gene_name": "ANXA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAMVSEFLKQAWFIENEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEALHKAITVRGVDEATIIEILTKRNNAQRQQIKAAYLQEKGKPLDEVLKKALLGHLEEVVLALLKTPAQFDAEELRAAMKGLGTDEDTLNEILASRTNREIREINRVYREELKRDLAKDIASDTSGDYEKALLSLAKGDRSEELAVNDDLADSDARALYEAGERRKGTDVNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGDIEKCLTVIVKCATSQPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCGRD", "length": 346 }, "evidence": [ { "id": "A0A8V0YMS3", "url": "https://omabrowser.org/oma/group/A0A8V0YMS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SJB5-1", "protein_name": "Annexin", "gene_name": "ANXA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAMVSEFLKQAWFIDNEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEALHKAITVKGVDEATIIEILTKRTNAQRQQIKAAYLQEKGKPLDEALKKALTGHLEEVALALLKTPAQFDADELRAAMKGLGTDEDTLNEILASRTNREIREINRVYKEELKRDLAKDITSDTSGDYQKALLSLAKGDRSEDLAINDDLADTDARALYEAGERRKGTDLNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGDIENCLTVVVKCATSKPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCGGD", "length": 346 }, "evidence": [ { "id": "A0A8V0YMS3", "url": "https://omabrowser.org/oma/group/A0A8V0YMS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I5L3-1", "protein_name": "Annexin", "gene_name": "Anxa1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAMVSEFLKQAWFIDNQEQEYVQAVKSSKGGPGSAVSPYPSFNPSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAYLQETGKPLDEMLRKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILVSRNNREIREINRVYREELKRDLAKDITSDTSGDFRKALLSLAKGDRCEDLSVNQDLADTDARALYEAGERRKGTDTNVFITILTTRSKSHLRKVFQNYRKYSEHDMNKVLDLEMKGDIEKCLTALVKCSTSTPAFFAEKLYEAMKGAGTRHKALIRIMVSRSEIDMNEIKAFYLKKYGISLCQAILDETKGDYEKILVALCDGN", "length": 346 }, "evidence": [ { "id": "A0A8V0YMS3", "url": "https://omabrowser.org/oma/group/A0A8V0YMS3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P04083-1", "protein_name": "Annexin A1", "gene_name": "ANXA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN", "length": 346 }, "evidence": [ { "id": "A0A8V0YMS3", "url": "https://omabrowser.org/oma/group/A0A8V0YMS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07150-1", "protein_name": "Annexin A1", "gene_name": "Anxa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMVSEFLKQACYIEKQEQEYVQAVKSYKGGPGSAVSPYPSFNPSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLAMLKTPAQFDADELRAAMKGLGTDEDTLIEILTTRSNQQIREITRVYREELKRDLAKDITSDTSGDFRNALLALAKGDRCEDMSVNQDLADTDARALYEAGERRKGTDVNVFNTILTTRSYPHLRKVFQNYRKYSQHDMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKGAGTRHKTLIRIMVSRSEIDMNEIKVFYQKKYGIPLCQAILDETKGDYEKILVALCGGN", "length": 346 }, "evidence": [ { "id": "A0A8V0YMS3", "url": "https://omabrowser.org/oma/group/A0A8V0YMS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10107-1", "protein_name": "Annexin A1", "gene_name": "Anxa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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[ "Protein Classification", "Other" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU67-1", "database": 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"https://www.ensembl.org/id/ENSGALP00010022284.1" } ] } }, { "isoform_ac": "A0A8V0YU67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU67/entry", "sequence": { "sequence": "MCNFLQGETRNPEEEGSAWVGGLSASLPSLGMSGSTGTAAHTLLLLLLAPVWVGAQGCTFPCQCPSQPLQCPAGTSHVLDACGCCKVCARQLGELCSLQKPCDHHKGLYCDFSSIHRGSGICLAREGATCDLLGKVYHNGESFQPTCKLQCICLDGAIGCIPLCSADLRLPSPDCPHPRRVKMHNKCCEEWVCEEGGQEDRLETVLAVFREDPEREPELNNLQENCLVQTTEWSACSKSCGMGISARVTNNNPQCHLEKETRLCMVRPCDFPWEKAKKGKKCVRTPRPCRRLLFEFSGCTSTRSYRPKFCGSCVDGRCCTPYITSTAEVEFRCPEGDSFQRKMMFIKSCSCHYDCPRDNDIFLATYHRRMIGDHVKTDRQ", "length": 380, "header": "tr|A0A8V0YU67-1|A0A8V0YMS7_CHICK Computationally mapped isoform of CCN family member 3 OS=Gallus gallus OX=9031 GN=CTGFL PE=3 SV=1 CANONICAL=A0A8V0YMS7-1" }, "locus": { "chromosome": "23", "start_pos": 2953435, "end_pos": 2946996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038508.1", "url": "https://www.ensembl.org/id/ENSGALT00010038508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022281.1", "url": "https://www.ensembl.org/id/ENSGALP00010022281.1" } ] } }, { "isoform_ac": "A0A8V0Z0X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X2/entry", "sequence": { "sequence": "MVAVFLLPEEGRLSCAWDSTLLPVLLVLHLLPLSSRSVYAEDKPGAGSCMHRAACRRGTKRRPTRWLCRRWDALNQVDAFISPAALRHTHSLWLLCPAAREGATCDLLGKVYHNGESFQPTCKLQCICLDGAIGCIPLCSADLRLPSPDCPHPRRVKMHNKCCEEWVCEEGGQEDRLETVLAVFREDPEREPELNNLQENCLVQTTEWSACSKSCGMGISARVTNNNPQCHLEKETRLCMVRPCDFPWEKAKKGKKCVRTPRPCRRLLFEFSGCTSTRSYRPKFCGSCVDGRCCTPYITSTAEVEFRCPEGDSFQRKMMFIKSCSCHYDCPRDNDIFLATYHRRMIGDHVKTDRQ", "length": 355, "header": "tr|A0A8V0Z0X2-1|A0A8V0YMS7_CHICK Computationally mapped isoform of CCN family member 3 OS=Gallus gallus OX=9031 GN=CTGFL PE=3 SV=1 CANONICAL=A0A8V0YMS7-1" }, "locus": { "chromosome": "23", "start_pos": 2953435, "end_pos": 2949839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038505.1", "url": "https://www.ensembl.org/id/ENSGALT00010038505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022280.1", "url": "https://www.ensembl.org/id/ENSGALP00010022280.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS7" }, { "id": "PS01225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTCK", "eco_id": "ECO_0000259", 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPK2-1", "uniprot_ac": "A0A8V0YPK2", "uniprot_id": "A0A8V0YPK2_CHICK", "mass": { "chemical_mass": 206930.0, "monoisotopic_mass": 206930.0 }, "refseq": { "ac": "XP_003641084", "name": "adenylate kinase 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641084" }, "gene_names": [ { "name": "AK9", "type": "recommended", "evidence": [ { "id": "A0A8V0YPK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ] }, { "name": "AK9", "type": "synonym", "evidence": [ { "id": "XP_003641084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641084" } ] } ], "protein_names": [ { "name": "Adenylate kinase 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YPK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2/entry#names_and_taxonomy" } ] }, { "name": "adenylate kinase 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641084" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641084.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641084" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2", "locus": { "chromosome": "3", "start_pos": 66606608, "end_pos": 66550456, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014124", "url": "https://www.ensembl.org/id/ENSGALG00010014124" } ] } } ], "crossref": [ { "id": "cd01428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771077", "url": "https://www.ncbi.nlm.nih.gov/gene/771077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771077", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MESVCGT", "url": "https://omabrowser.org/oma/group/MESVCGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS8", "url": "https://www.orthodb.org/?gene=A0A8V0YMS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YPJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK2", "url": "https://www.orthodb.org/?gene=A0A8V0YPK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASREEKQSQPFADIFNEDEAEKFFLLSKPTCIMVLGKPGSGKKTLARKIAQIWKCILIEASEVIQMNIHEETEYGLKCQELLFKGQSISEELVTEMILEKIESPEVAHFGYVLSGFPSLSEEYMTVSQQMEKIKNLKLKPDFLINIKCSDYDLCQRISGQRQRPDSGQVYQRNQWDPDLIEKQKKNSDQLEDENEEVEAEEMEEEIAQDSLTMSEMIHQLVQRPEDMLENIQERVGLYKDIMLRSLEDLMAEQDSQYLIELDGNQEPDELLASVVIRLQSMGVRNGAPIIRLQSQQEEMLEGLENDELFRVLSSVKLIAPRYRWRRSRWGQVCPVALKKGDILMGIPDLAVSFLGKMYTLSSPEALKAFMLNPRPYLLPPMPMPPCKVLVFGPPVSGRTTICNLIANKYKGKVLDMAELIQSHVEELREKNIEQRDAIEKTITAMENRLEFEKQLEEPGGLEELSVKEADNSEETEKMRKEINFEEGSSTEETAVIPEEMLELSADHPEVQAMVEEAVESASESEVTLSPEIYAEVLERAIAELMKKNKDRFPGAPEKGGWVVDNYPLSEDHWSALSERGLLPDTVVCLKDTENDGGCILHRTYLANKDEINSKILRRLADEALKKEEEEEEERREMQEMLTPEEEEQSQEDAEKKESEDDDKQLSSETEQTSQKQSSDSADYTEESETTEIMLPEFEENDLLDLPEMQTIKEKIDLFMNDWQTMESEIKQSSLVQVVALEIAEQTPESLLNQIILVMEEPFKYHGWELSNEDLDEEAEDLAAEAEAIEDNEAEEEENEEDEEKAKERKRHMGDTKHFCPVSLKEDYVLYPGLPEHAAKYQEKIYYFSNLEYRDKFLKNPEEYVAHNEPLQAPPLRVCLLGTRGSGKTACARWLADKFGIFHIQFKEYLQELLLPKTKEKIGLDFDEEPEEADDEIQLQELQDLSQTTTKTDDEESKQEVELTEEEEAIKANLMDAQPLPPEILDNIVPVWWKKEPFRSTGFILDGFPRTSDEAQYLSERGLCPDAAVYIHVEESEILDRLLPPRLKKWKERQHKKAEIKKKLKDLKAKIKNEKIARRRAELLAEQKKRKEKVLEDGENYETSEEEDETANEDIEAILEEEFFEEEEEEPEEEQEIDAVERMQNEIVERFDSERESIEGVQEELQNFLIPQMEINGRRKLRIVRYQIYCKLNSLVENRGSIFEKCYPISLPLAHKMLVFSYKFPSSFSQWDPIKLKEGEIIKPAQNYETTLLPVIHRQYVYFFSSKKNRETFMNNPIKYICQPKPKPPVPVKIAIVGPPKSGKTTVAKKFESTYGLRRLSMGDAIRLVLNNQPESELGLQLKCHLHRGLTVPDELAIQALDVALMDHVCSTTGVVIDGYPVTRKQVNLLESARIIPLKIFELEMDAKEVFRRALLDKESTNRPSYPVHDSTQILAIKNSYYREHIDAIRTYYKKERQNWCVIDAFQSKWWMWDKVLREVQVIVKEIQIYLERIKEGKAASIADLCITPEELQYRLGEFGQYCPVSLADKGELVDCSVTSSLQFAAEFRAHYYKMASQEELDKFLNRPEVYVPPLAPHPLPPPDKLPQRLTAAEVKALFPISAEMQGYCPVTYLDGKQRYEALVPGNTEYAAKYQDKLYVFESEEKLLKFMRLPEKYWNLKLPHKLPPVREPILLTALPMAGYLEQGVATSLIKALNEVGCLKPKFPFLSVRRTALLFVACHLKAYNARSPAHRRQAYRRRLARLTEHCELIPYLGRAMPREYTEPQHRPLGFDLKLQTFLSLKDAGPSFV", "length": 1791, "header": "tr|A0A8V0YPK2-1|A0A8V0YPK2_CHICK Isoform 1 of Adenylate kinase 9 OS=Gallus gallus OX=9031 GN=AK9 PE=4 SV=1 CANONICAL=A0A8V0YPK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS8/entry", "sequence": { "sequence": "MASREEKQSQPFADIFNEDEAEKFFLLSKPTCIMVLGKPGSGKKTLARKIAQIWKCILIEASEVIQMNIHEETEYGLKCQELLFKGQSISEELVTEMILEKIESPEVAHFGYVLSGFPSLSEEYMTVSQQMEKIKNLKLKPDFLINIKCSDYDLCQRISGQRQRPDSGQVYQRNQWDPDLIEKQKKNSDQLEDENEEVEAEEMEEEIAQDSLTMSEMIHQLVQRPEDMLENIQERVGLYKDIMLRSLEDLMAEQDSQYLIELDGNQEPDELLASVVIRLQSMGVRNGAPIIRLQSQQEEMLEGLENDELFRVLSSVKLIAPRYRWRRSRWGQVCPVALKKGDILMGIPDLAVSFLGKMYTLSSPEALKAFMLNPRPYLLPPMPMPPCKVLVFGPPVSGRTTICNLIANKYKGKVLDMAELIQSHVEELREKNIEQRDAIEKTITAMENRLEFEKQLEEPGGLEELSVKEADNSEETEKMRKEINFEEGSSTEETAVIPEEMLELSADHPEVQAMVEEAVESASESEVTLSPEIYAEVLERAIAELMKKNKDRFPGAPEKGGWVVDNYPLSEDHWSALSERGLLPDTVVCLKDTENDGGCILHRTYLANKDEINSKILRRLADEALKKEEEEEEERREMQEMLTPEEEEQSQEDAEKKESEDDDKQLSSETEQTSQKQSSDSADYTEESETTEIMLPEFEENDLLDLPEMQTIKEKIDLFMNDWQTMESEIKQSSLVQVVALEIAEQTPESLLNQIILVMEEPFKYHGWELSNEDLDEEAEDLAAEAEAIEDNEAEEEENEEDEEKAKERKRHMGDTKHFCPVSLKEDYVLYPGLPEHAAKYQEKIYYFSNLEYRDKFLKNPEEYVAHNEPLQAPPLRVCLLGTRGSGKTACARWLADKFGIFHIQFKEYLQELLLPKTKEKIGLDFDEEPEEADDEIQLQELQDLSQTTTKTDDEESKQEVELTEEEEAIKANLMDAQPLPPEILDNIVPVWWKKEPFRSTGFILDGFPRTSDEAQYLSERGLCPDAAVYIHVEESEILDRLLPPRLKKWKERQHKKAEIKKKLKDLKAKIKNEKIARRRAELLAEQKKRKEKVLEDGENYETSEEEDETANEDIEAILEEEFFEEEEEEPEEEQEIDAVERMQNEIVERFDSERESIEGVQEELQNFLIPQMEINGRRKLRIVRYQIYCKLNSLVENRGSIFEKCYPISLPLAHKMLVFSYKFPSSFSQWDPIKLKEGEIIKPAQNYETTLLPVIHRQYVYFFSSKKNRETFMNNPIKYICQPKPKPPVPVKIAIVGPPKSGKTTVAKKFESTYGLRRLSMGDAIRLVLNNQPESELGLQLKCHLHRGLTVPDELAIQALDVALMDHVCSTTGVVIDGYPVTRKQVNLLESARIIPLKIFELEMDAKEVFRRALLDKESTNRPSYPVHDSTQILAIKNSYYREHIDAIRTYYKKERQNWCVIDAFQSKWWMWDKVLREVQVIVKEIQIYLERIKEGKAASIADLCITPEELQYRLGEFGQYCPVSLADKGELVDCSVTSSLQFAAEFRAHYYKMASQEELDKFLNRPEVYVPPLAPHPLPPPDKLPQRLTAAEVKALFPISAEMQGYCPVTYLDGKQRYEALVPGNTEYAAKYQDKLYVFESEEKLLKFMRLPEKYWNLKLPHKLPPVREPILLTALPMAGYLEQGVATSLIKALNEVGCLKPKFPFLSVRRTALLFVACHLKDSCNLHYLSAVLHIQCFPMQLQEPFTVFLDYHRLLLV", "length": 1761, "header": "tr|A0A8V0YMS8-1|A0A8V0YPK2_CHICK Computationally mapped isoform of Adenylate kinase 9 OS=Gallus gallus OX=9031 GN=AK9 PE=4 SV=1 CANONICAL=A0A8V0YPK2-1" }, "locus": { "chromosome": "3", "start_pos": 66604760, "end_pos": 66550787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033915.1", "url": "https://www.ensembl.org/id/ENSGALT00010033915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019936.1", "url": "https://www.ensembl.org/id/ENSGALP00010019936.1" } ] } }, { "isoform_ac": "A0A8V0YPJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ7/entry", "sequence": { "sequence": "MASREEKQSQPFADIFNEDEAEKFFLLSKPTCIMVLGKPGSGKKTLARKIAQIWKCILIEASEVIQMNIHEETEYGLKCQELLFKGQSISEELVTEMILEKIESPEVAHFGYVLSGFPSLSEEYMTVSQQMEKIKNLKLKPDFLINIKCSDYDLCQRISGQRQRPDSGQVYQRNQWDPDLIEKQKKNSDQLEDENEEVEAEEMEEEDLMAEQDSQYLIELDGNQEPDELLASVVIRLQSMGVRNGAPIIRLQSQQEEMLEGLENDELFRVLSSVKLIAPRYRWRRSRWGQVCPVALKKGDILMGIPDLAVSFLGKMYTLSSPEALKAFMLNPRPYLLPPMPMPPCKVLVFGPPVSGRTTICNLIANKYKGKVLDMAELIQSHVEELREKNIEQRDAIEKTITAMENRLEFEKQLEEPGGLEELSVKEADNSEETEKMRKEINFEEGSSTEETAVIPEEMLELSADHPEVQAMVEEAVESASESEVTLSPEIYAEVLERAIAELMKKNKDRFPGAPEKGGWVVDNYPLSEDHWSALSERGLLPDTVVCLKDTENDGGCILHRTYLANKDEINSKILRRLADEALKKEEEEEEERREMQEMLTPEEEEQSQEDAEKKESEDDDKQLSSETEQTSQKQSSDSADYTEESETTEIMLPEFEENDLLDLPEMQTIKEKIDLFMNDWQTMESEIKQSSLVQVVALEIAEQTPESLLNQIILVMEEPFKYHGWELSNEDLDEEAEDLAAEAEAIEDNEAEEEENEEDEEKAKERKRHMGDTKHFCPVSLKEDYVLYPGLPEHAAKYQEKIYYFSNLEYRDKFLKNPEEYVAHNEPLQAPPLRVCLLGTRGSGKTACARWLADKFGIFHIQFKEYLQELLLPKTKEKIGLDFDEEPEEADDEIQLQELQDLSQTTTKTDDEESKQEVELTEEEEAIKANLMDAQPLPPEILDNIVPVWWKKEPFRSTGFILDGFPRTSDEAQYLSERGLCPDAAVYIHVEESEILDRLLPPRLKKWKERQHKKAEIKKKLKDLKAKIKNEKIARRRAELLAEQKKRKEKVLEDGENYETSEEEDETANEDIEAILEEEFFEEEEEEPEEEQEIDAVERMQNEIVERFDSERESIEGVQEELQNFLIPQMEINGRRKLRIVRYQIYCKLNSLVENRGSIFEKCYPISLPLAHKMLVFSYKFPSSFSQWDPIKLKEGEIIKPAQNYETTLLPVIHRQYVYFFSSKKNRETFMNNPIKYICQPKPKPPVPVKIAIVGPPKSGKTTVAKKFESTYGLRRLSMGDAIRLVLNNQPESELGLQLKCHLHRGLTVPDELAIQALDVALMDHVCSTTGVVIDGYPVTRKQVNLLESARIIPLKIFELEMDAKEVFRRALLDKESTNRPSYPVHDSTQILAIKNSYYREHIDAIRTYYKKERQNWCVIDAFQSKWWMWDKVLREVQVIVKEIQIYLERIKEGKAASIADLCITPEELQYRLGEFGQYCPVSLADKGELVDCSVTSSLQFAAEFRAHYYKMASQEELDKFLNRPEVYVPPLAPHPLPPPDKLPQRLTAAEVKALFPISAEMQGYCPVTYLDGKQRYEALVPGNTEYAAKYQDKLYVFESEEKLLKFMRLPEKYWNLKLPHKLPPVREPILLTALPMAGYLEQGVATSLIKALNEVGCLKPKFPFLSVRRTALLFVACHLKAYNARSPAHRRQAYRRRLARLTEHCELIPYLGRAMPREYTEPQHRPLGFDLKLQTFLSLKDAGPSFV", "length": 1749, "header": "tr|A0A8V0YPJ7-1|A0A8V0YPK2_CHICK Computationally mapped isoform of Adenylate kinase 9 OS=Gallus gallus OX=9031 GN=AK9 PE=4 SV=1 CANONICAL=A0A8V0YPK2-1" }, "locus": { "chromosome": "3", "start_pos": 66606347, "end_pos": 66550787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033918.1", "url": "https://www.ensembl.org/id/ENSGALT00010033918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019937.1", "url": "https://www.ensembl.org/id/ENSGALP00010019937.1" } ] } }, { "isoform_ac": "A0A8V0YPK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2/entry", "sequence": { "sequence": "MASREEKQSQPFADIFNEDEAEKFFLLSKPTCIMVLGKPGSGKKTLARKIAQIWKCILIEASEVIQMNIHEETEYGLKCQELLFKGQSISEELVTEMILEKIESPEVAHFGYVLSGFPSLSEEYMTVSQQMEKIKNLKLKPDFLINIKCSDYDLCQRISGQRQRPDSGQVYQRNQWDPDLIEKQKKNSDQLEDENEEVEAEEMEEEIAQDSLTMSEMIHQLVQRPEDMLENIQERVGLYKDIMLRSLEDLMAEQDSQYLIELDGNQEPDELLASVVIRLQSMGVRNGAPIIRLQSQQEEMLEGLENDELFRVLSSVKLIAPRYRWRRSRWGQVCPVALKKGDILMGIPDLAVSFLGKMYTLSSPEALKAFMLNPRPYLLPPMPMPPCKVLVFGPPVSGRTTICNLIANKYKGKVLDMAELIQSHVEELREKNIEQRDAIEKTITAMENRLEFEKQLEEPGGLEELSVKEADNSEETEKMRKEINFEEGSSTEETAVIPEEMLELSADHPEVQAMVEEAVESASESEVTLSPEIYAEVLERAIAELMKKNKDRFPGAPEKGGWVVDNYPLSEDHWSALSERGLLPDTVVCLKDTENDGGCILHRTYLANKDEINSKILRRLADEALKKEEEEEEERREMQEMLTPEEEEQSQEDAEKKESEDDDKQLSSETEQTSQKQSSDSADYTEESETTEIMLPEFEENDLLDLPEMQTIKEKIDLFMNDWQTMESEIKQSSLVQVVALEIAEQTPESLLNQIILVMEEPFKYHGWELSNEDLDEEAEDLAAEAEAIEDNEAEEEENEEDEEKAKERKRHMGDTKHFCPVSLKEDYVLYPGLPEHAAKYQEKIYYFSNLEYRDKFLKNPEEYVAHNEPLQAPPLRVCLLGTRGSGKTACARWLADKFGIFHIQFKEYLQELLLPKTKEKIGLDFDEEPEEADDEIQLQELQDLSQTTTKTDDEESKQEVELTEEEEAIKANLMDAQPLPPEILDNIVPVWWKKEPFRSTGFILDGFPRTSDEAQYLSERGLCPDAAVYIHVEESEILDRLLPPRLKKWKERQHKKAEIKKKLKDLKAKIKNEKIARRRAELLAEQKKRKEKVLEDGENYETSEEEDETANEDIEAILEEEFFEEEEEEPEEEQEIDAVERMQNEIVERFDSERESIEGVQEELQNFLIPQMEINGRRKLRIVRYQIYCKLNSLVENRGSIFEKCYPISLPLAHKMLVFSYKFPSSFSQWDPIKLKEGEIIKPAQNYETTLLPVIHRQYVYFFSSKKNRETFMNNPIKYICQPKPKPPVPVKIAIVGPPKSGKTTVAKKFESTYGLRRLSMGDAIRLVLNNQPESELGLQLKCHLHRGLTVPDELAIQALDVALMDHVCSTTGVVIDGYPVTRKQVNLLESARIIPLKIFELEMDAKEVFRRALLDKESTNRPSYPVHDSTQILAIKNSYYREHIDAIRTYYKKERQNWCVIDAFQSKWWMWDKVLREVQVIVKEIQIYLERIKEGKAASIADLCITPEELQYRLGEFGQYCPVSLADKGELVDCSVTSSLQFAAEFRAHYYKMASQEELDKFLNRPEVYVPPLAPHPLPPPDKLPQRLTAAEVKALFPISAEMQGYCPVTYLDGKQRYEALVPGNTEYAAKYQDKLYVFESEEKLLKFMRLPEKYWNLKLPHKLPPVREPILLTALPMAGYLEQGVATSLIKALNEVGCLKPKFPFLSVRRTALLFVACHLKAYNARSPAHRRQAYRRRLARLTEHCELIPYLGRAMPREYTEPQHRPLGFDLKLQTFLSLKDAGPSFV", "length": 1791, "header": "tr|A0A8V0YPK2-1|A0A8V0YPK2_CHICK Isoform 1 of Adenylate kinase 9 OS=Gallus gallus OX=9031 GN=AK9 PE=4 SV=1 CANONICAL=A0A8V0YPK2-1" }, "locus": { "chromosome": "3", "start_pos": 66606347, "end_pos": 66550787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033926.1", "url": "https://www.ensembl.org/id/ENSGALT00010033926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019942.1", "url": "https://www.ensembl.org/id/ENSGALP00010019942.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771077", "resource": "KEGG Pathway" }, { "id": "R-GGA-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R9YJL3-1", "protein_name": "Adenylate kinase 9 isoform X1", "gene_name": "ak9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSDLIVSNLPLVDKLIEDEAERAILLSKPACFIIIGKPGVGKSTLAKKIAKTWNCILIDDTDVLNNHINNETDQGKQLFRILAEGKAVPEEMMVNLIVDRLKSPDIKHYGYVLACLPSISEEYMKIQEQIDLIKTLKMSPDFIINIKCADRDLIRRLSEERQHPETGCVFPKEKWDPDKKESLMKQSNMEEEEEEEEEGEEETTEDLEVEEIEEIQLQKDVIAQLVRVTENYPENVTSRIKCYKDNILRPLEDYMAGHNPPYLFELDGNTDPEELFESVMSHLEFMAVRCPAVPVQLMPTEDAELTDQMEPEELFRTLSSCRNVAPGFPWRTSRWAFNCPVALKEGKVIKGKPEFAVGFMDKIYVLSSDDALQKFMANPRCYLLQPKPHVPCRVSVIGPPRSGKSTMCGLLAEKYGALVVDVRELMERNQGLLKQDMLNKVRHDATIAGLEKVRAKMELEATAIEVTEDHPDVQAFVEEAIKEAAESPAPRELYLDALEKHIKEIEAEDADAESKRGWILDIPSSRSHLITIEEIHGALTPEIIFCLKDNDREGRTVLTRMYERNKEEVDQAVMTRLQNQRNLQKTQDHETLKHSEDSKKDSQYSDTLSKLETVHEESESSDKSDDEGKTPSKNEVVLPTVWENGHPDGPEMDVFKVELKQFVTDWESMEQTITCSYAVLEINNKTPQGILQEMTDHMEKPFKHKAIMTSSADLEEEEEAIHMLIQAEKQDDVVNEEEEQESEEFNFKRQLGDTKHFCPVVLKEKGLLQPCLDEYAAKYRDKVYYFSSKEALEKFLQNPELYISNKELLKPPALRVSMLGVRGSGKTTHGKWLAQQLGIFHIQFRERLQELIQRKTQKRVSPADDSEPPEEPPEELQSLLKAQARIQSAESPTDQDNTTSLEETASGSPDAKEEEALTEDEEAIKAYLQNGDPLPSEILEMLLFQWWNQEPYKSTGFILEGFPQNHEEVSFMAEHHLFPDVVAVMSVEVSEVVRRLLPSRLNRWRERRERKQQQIHLVMKLRKEIRERAITKRRAEIMAEQAFRKLSPPTLSPLKEQEEEEEKEEAVDEEQELEEIEAMLLEEFPPEDEEETEDEEQETEESAEERLEVEISERFEKDDDNLTSMTDLLSDNQIPRLVISAGRLPRIVRYQLLKEIKPLMENRDSLFQTCQPISYSLARRLLYCSFKYPSAFGCWDPVKYTEGDLIQPPQDSYHSTFPVILHQFIYFFASKETRNTFILNPIKYLRQPRPNPSLPIKLAIIGPPKSGKTTVAQAFAREYGLTRLSIGDAIRMVLNSQAKTDLACQVQIHLKQGQTVPDELAIQCVEVAVMNLVCTTRGFVLDGFPVTKHQAELLESCIIPMVVVELQLDTVEVLKRGLRDREKNNRSHQVHHDSLQALNIRNSCFRQEAEALRLHLHNQYHNWTPVDAHKSKWWVQERILDEVRISMRHIHSYLERIHKGQAACINRLCITPQELQSRLGEFGHYCPVSLALHRHLVDCSHNTSLELAAEFKGQFYKMASREFLERFLESPEQFVAPGCPYPLPPASLLPHKLSAGQVKSRFPQQVEMKGFCPVTYLDGKQRYEALLRGNMEYAAEYRNKIYIFESEKKQEQFLRSPETYWDQKLPHKLPPLEEPVLLTSLPILGYLEQSVAVPIIKAMTDVGQLKPKFPFLSVKRSAILYLAFHLKAFNSRNSEYIRQKYKKKLQKFEEGCELISYLSTTMKTYKSPLNLPTEFLQKLDRFLALEKSTKTDSGLIQLGGI", "length": 1762 }, "evidence": [ { "id": "A0A8V0YPK2", "url": "https://omabrowser.org/oma/group/A0A8V0YPK2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M632-1", "protein_name": "Adenylate kinase 9", "gene_name": "Ak9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEEKTEEHPFADIFNEDETDRNCLLSKPACFIIFGKPGVGKTTLARSIAQAWKCIRVEAISVLEEHIAAENETGTMLQSLLVSGHTVPDELVTKLVLEKIKSPEVSHFGYILTEIPSLSQDNMTSLKQIEIIKHLELQPDVIINIKCSDYDLCQRISGQRQHSTTGYIYTREQWDPEIIESRRKKKKEVLKEGKAEEEEEEEQEEEEEAFLAEMQMVTETLQYLVQRPEDYLENIEVTVNLYKELLLNALEEVMAEHNPQYLIELDGNKPPEELFLTVIERLKYLNVRRAAIITKLQGTEEEMTDIIDTEELFRTVSSYKLMGPRYRWNRSKWARACPVSLKDGNIYPGAADFSVSFLGKMYCLSSEETLKLFLLNPRPFLLPPMPLPPCKVFIFGPNHSGKTTLANLIAEHFKAKVIDYATLVQPRFDSAREKLIKDTISEATNTAIKLVKERLLNDLRVKKQEEKTLKELRMHYTKKEYEDFSDYKKTKSSEEFPSSADDPEAQGSRNLSALEIGPEDKSRSENTISGDTDKDGSPEELIEEVTENHPEVFAMIEDTLRHSKELNFEQPYDKQAEILEEVIKEVTKDNKNRFAGAPKYGGWIVKNFPIMRELWMSLIEKALLPDLVVNLSDTESNGKIVLTRLYLSNKAEINAKILERLKEELQVKKREEDEIRKVKEEELRLEEEKQRMMELEAKKAKVVEEPDNEAEEEVDVEESEIHEETEAQEMGELARESSIPGGSESSEVPEAEHDPEAEFKAPEDTAVEAETEKGSKETLELEEQLKAMLPEFPEDGYPNVPEMEPLKEVLANYLIAWKQLEPIISDSLVPVLTVDISNKTPKELLQRVIEMMEKPFKYGAWELNAEDYEEEAEDYQAEMEVEEEQEEEEEEEEEGEEKSKERRRHLGDTKHFCPVVLKENFVLQPGSTEEAVKYREKIYYFSTPEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFEEFLQERMLLKAERKFGPEFEDDSEEEQAMKQELEELAAQANVKIEEDNTKKQLPEVQFTEEEEAIKLSLTDNEPLPSEILDPMLSEWWLKEPIRSTGFILDGFPRYPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQLKKSERKKMIKEMKAKIKEDMVAKRRAELISEREKRKKGEGAFRDEEEFSDEDAEDEDDIENILEEEFPKDEEEMSEEDEEQEGDATERLRSELGEKFETETNNIQSIQDEFERFLIPIIPVNGARKMHIVQYVLNVKLKPLVENRASIFEKCYPVSPHLAHKMLAFTYKHMSSFGYWDPVKLSEGETIKPVETAENPLNPIIHRHYIYFLSTKQTKEKFMMNPIKYIRQPKPKASMPVRIMIVGPPKSGKSTVAKQLANDYGLKCLSMGDALRGMLSNHPEAELSLRINWHLHKGMTVPDDLAIQALDISLLDSVCNTVGVVIDGYPVTPHQVELLEARSIIPMIIFELDVPSKEIFKRLLLEKKSEQGMPYPMHNSTQIIAYRNAKYRKNVNEIRQFYQRQHQNWHVIDGFHSKWWVWNEVIKDIQQMNKYIQTYMEKIKEGKAACIDKLCITPEELISRLGEFKQFCPVSLAESNELIDCSVTSSLEFTAEFRGHYYKMSSQEKLNKFLKNPELYVPPLAPHPLPPDDMLPKRLTLSELKSRFPMSAELQGYCPVTYKDGKQRYEALVPGDNEYAVEYRGRIYICESEEKLQKFLRLPMKYWDQKLPHKLPPPKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKMEQFVERCELITYLSSKMTRKFKEPQFRPIDFDHKLQTFMSLKNIDPVTG", "length": 1889 }, "evidence": [ { "id": "A0A8V0YPK2", "url": "https://omabrowser.org/oma/group/A0A8V0YPK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UYQ4-1", "protein_name": "Adenylate kinase 9", "gene_name": "Ak9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEEKTEELHPFTDIFNEDETDRNCLLSKPTCFIIFGKPGAGKTTLARNIAQAWKCIRVEALSVLEEHIAAEKETGAMLQSLLVSGHSIPDELVTKLILEKIKSPEVAHFGYILTEMPSLAQDNMTSLKQIELVKNLELQPDIIINIKCSDYDLCQRTCGQRQHSTTGYVYTREQWDPEIIESRRRKKRDFPKEGKSEEEEEEEEQEEEEAFIAEMQMVAEILQHLVQRPEDYLENVEITVKLYKELLLSALEEVMAEHNPQYLIELDGNKSPEELFMTVIERLKYLNVRRAAVITKLQGTEEEMTDIIDTEELFRTVSSYKLIAPRYRWYRSKWARSCPVSLKDGNIYSGAADYTVSFLGKMYCLSSEETLKLFSLNPRPFLLPPMPLPPCKVFIFGPEHIGKTTLANLIAEHFKAKVIDYAKLVQPRFDSAREKLIKDTITEATNTAIKVVQQRLLNEKQAKQQEERTLKELQVQYSKREYNDFLSKSSEELPSLENTGSKLSSLEIGQEDKSKSETTITGDQVKDVSTEESIEEVTENHPEVFAILEDTLRHAKELNFEQPHDKQAEILEEVIKETEDNKNRFPGAPKHGGWIVENFPLVRELWLSLIEKALLPDLVVYLSDAESNGKHVLNRLYLKNKAEIDGKILERLQEEAQAKKREEEEIRKVKEEELRLEEEKQRLMELATKKSKGRHRLTTLVAHHLALPYPDYPDNEAEEEVEDSEIHEESEAQEIPEYTRGSSLPEASETSETPEGDHEPEAEFKPPGDTAVEAETEKDPKEGLGSEDLLKVMLPEFPEDGYPNVPEMEPLKEVLNNHILSWKQLEQTIMDNVVSTLTVDVSNKTPQELLQRVVETMERPFKYSAWELNAEDYEEEAEDYQAETEIDEEQEEEEEEEEEGEEKIKEKRRHMGDTKHFCPVVLKENFVLQPGNPDEAVKYREKIYYFSSTEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFDEFLQEKMLLKAERKFGPEFEDDSEEEQLVKQELEELAAQANVKIEEDTTKKQLPDVQLTEEEEAIKLSLTDNEPLPSEILDSILSEWWLKEPIRSTGFILDGFPRHPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQHKKLERKKLIKDLKTKIKEDMVAKRRAELILEREKKRREDGTFRDEDEFSDEDADYEDDIENILEEEFPKDEEEMSEEDEEQEADATERLRNELGEKFETETNNIQSIQDEFDKVLIPIIMVNGARKMHIVQYVMNMKLKPLVENRESIFEKCYPVSSHLAHKMLSYTYKHMSSFGYWDPVKLSEGETIKPVENAENPLNPVIHRHYIYFLSNKQTKEKFMMNPIKYIRQPKPKATMPVRIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLNNHPDSELSLMLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLEARSIIPMVIFELHVPSKEIFKRLLLEKKTEQSMSYPLHNSSQIIAYKNAKYHKNINEIRQFYQKQHQNWHVIDGFHSKWWVWNEVLKDIQQMNKYIQTYMKKIKEGKAACIDKLCITPEELIARLGEFKQFCPVSLAESNELIDCSVTSSLEFAAEFRGHYYKMSSQEKLNKFLKDPELYVPPLAPHPLPPDDLLPKRLTLSELKSRFPKCAELQGYCPVTYQDGKQRYEALVPGNIRYALEYRNCIYICESEEKLQKFMRSPMQYWNQKLPRKLPPLKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKLEQFVERCELITYLSSKMTRKYKEPQFRAIDFDHKLQTFLSLKNIDPVTG", "length": 1894 }, "evidence": [ { "id": "A0A8V0YPK2", "url": "https://omabrowser.org/oma/group/A0A8V0YPK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5TCS8-4", "protein_name": "Adenylate kinase 9", "gene_name": "AK9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRASIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQYIYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAACIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEKLNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRYEALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPLPGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKKKMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING", "length": 1911 }, "evidence": [ { "id": "A0A8V0YPK2", "url": "https://omabrowser.org/oma/group/A0A8V0YPK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "nucleobase-containing compound kinase activity", "id": "GO:0019205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019205", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "CDP biosynthetic process", "id": "GO:0046705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046705", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK2" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 324, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YMY2-1", "uniprot_ac": "A0A8V0YMY2", "uniprot_id": "A0A8V0YMY2_CHICK", "mass": { "chemical_mass": 57259.0, "monoisotopic_mass": 57259.0 }, "refseq": { "ac": "XP_040507679", "name": "gap junction alpha-9 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507679" }, "gene_names": [ { "name": "GJA9", "type": "recommended", "evidence": [ { "id": "A0A8V0YMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2" } ] }, { "name": "GJA9", "type": "synonym", "evidence": [ { "id": "XP_040507679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507679" } ] } ], "protein_names": [ { "name": "Gap junction protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2/entry#names_and_taxonomy" } ] }, { "name": "gap junction alpha-9 protein", "type": "synonym", "evidence": [ { "id": "XP_040507679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507679" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507679" } ] }, { "annotation": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2#function" }, { "database": "UniProtKB", "id": "RU000630", "url": "https://www.uniprot.org/uniprotkb/RU000630#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GJA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2", "locus": { "chromosome": "23", "start_pos": 3622015, "end_pos": 3618254, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013541", "url": "https://www.ensembl.org/id/ENSGALG00010013541" } ] } } ], "crossref": [ { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859395", "url": "https://www.ncbi.nlm.nih.gov/gene/100859395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017990", "url": 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"MGDWNFLGGILEEVHIHSTIIGKIWLTILFVFRMLVLGVATEDVWNDEQSEFICNTEQPGCRNVCYDEAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRALEKERQKKKAQVRVELESTELEMTEYRKRLERELRQLDQRKLNKAPLRGSLLCTYVIHIFTRSAVEVGFMIGQYLLYGFRLDPLYKCQRDPCPNVVDCFVSRPTEKTVFILFMQSIATVSLLLNVLEIIHLGFRKIKIGLCGQEDNKDDRGNFYTNKSKKYSVIPRSSLGISATPQKTLPSVLSGYAFLMEKQTDTAIYPVLNSAPVFQPVQNNHTENRGNYTHHHQENKLPKKRPATNAVAGQTQNAGINCSEGLLGRPGTERRSSQKEADQKHFLAGAQNADTAPRSFAEMLSQPPLQPFPVASLRRQHGVVSSWNCSAAAESVGSSTNSLTKSSSRRRSSLSTSQGQLPPKADSRHPSRPDTPDSAGEASTGSKQSRGCGSPQPLPLSGRLSLSSSASSRRAPTDLQI", "length": 513, "header": "tr|A0A8V0YMY2-1|A0A8V0YMY2_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA9 PE=3 SV=1 CANONICAL=A0A8V0YMY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2/entry", "sequence": { "sequence": "MGDWNFLGGILEEVHIHSTIIGKIWLTILFVFRMLVLGVATEDVWNDEQSEFICNTEQPGCRNVCYDEAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRALEKERQKKKAQVRVELESTELEMTEYRKRLERELRQLDQRKLNKAPLRGSLLCTYVIHIFTRSAVEVGFMIGQYLLYGFRLDPLYKCQRDPCPNVVDCFVSRPTEKTVFILFMQSIATVSLLLNVLEIIHLGFRKIKIGLCGQEDNKDDRGNFYTNKSKKYSVIPRSSLGISATPQKTLPSVLSGYAFLMEKQTDTAIYPVLNSAPVFQPVQNNHTENRGNYTHHHQENKLPKKRPATNAVAGQTQNAGINCSEGLLGRPGTERRSSQKEADQKHFLAGAQNADTAPRSFAEMLSQPPLQPFPVASLRRQHGVVSSWNCSAAAESVGSSTNSLTKSSSRRRSSLSTSQGQLPPKADSRHPSRPDTPDSAGEASTGSKQSRGCGSPQPLPLSGRLSLSSSASSRRAPTDLQI", "length": 513, "header": "tr|A0A8V0YMY2-1|A0A8V0YMY2_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA9 PE=3 SV=1 CANONICAL=A0A8V0YMY2-1" }, "locus": { "chromosome": "23", "start_pos": 3621351, "end_pos": 3619813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032573.1", "url": "https://www.ensembl.org/id/ENSGALT00010032573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019297.1", "url": 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"name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2" }, { "id": "SM00037", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin N-terminal", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 76, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY2" }, { "id": "SM01089", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 233, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 420, "end_pos": 422 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN18-1", "uniprot_ac": "A0A8V0YN18", "uniprot_id": "A0A8V0YN18_CHICK", "mass": { "chemical_mass": 33238.0, "monoisotopic_mass": 33238.0 }, "refseq": { "ac": "NP_001026730", "name": "tumor necrosis factor ligand superfamily member 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" }, "gene_names": [ { "name": "FASLG", "type": "recommended", "evidence": [ { "id": "A0A8V0YN18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ] }, { "name": "FASLG", "type": "synonym", "evidence": [ { "id": "NP_001026730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ] }, { "name": "TNFSF6", "type": "synonym", "evidence": [ { "id": "NP_001026730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ] } ], "protein_names": [ { "name": "Tumor necrosis factor ligand superfamily member 6", "type": "recommended", "evidence": [ { "id": "A0A8V0YN18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18/entry#names_and_taxonomy" } ] }, { "name": "Fas antigen ligand", "type": "synonym", "evidence": [ { "id": "A0A8V0YN18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18/entry#names_and_taxonomy" } ] }, { "name": "apoptosis (APO-1) antigen ligand 1", "type": "synonym", "evidence": [ { "id": "NP_001026730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ] }, { "name": "tumor necrosis factor ligand superfamily member 6", "type": "synonym", "evidence": [ { "id": "NP_001026730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ890143.1, SRR12888501.602977.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Oct 28, 2021 this sequence version replaced NP_001026730.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ] }, { "annotation": "Cytoplasmic form induces gene transcription inhibition.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18#function" }, { "database": "UniProtKB", "id": "ARBA00003149", "url": "https://www.uniprot.org/uniprotkb/ARBA00003149#function" } ] }, { "annotation": "During primary Eimeria tenella infection, perforin, granzyme A and FasL mRNA expression in caecal tissue was significantly increased.", "evidence": [ { "database": "RefSeq", "id": "NP_001026730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" }, { "database": "PubMed", "id": "27136454", "url": "https://glygen.org/publication/PubMed/27136454" } ] }, { "annotation": "Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways. Can induce apoptosis but does not appear to be essential for this process.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18#function" }, { "database": "UniProtKB", "id": "ARBA00045660", "url": "https://www.uniprot.org/uniprotkb/ARBA00045660#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FASLG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18", "locus": { "chromosome": "8", "start_pos": 4466196, "end_pos": 4470188, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013583", "url": "https://www.ensembl.org/id/ENSGALG00010013583" } ] } } ], "crossref": [ { "id": "A0A8V0YN18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00184", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00184", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429064", "url": "https://www.ncbi.nlm.nih.gov/gene/429064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429064", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KVKRSAH", "url": "https://omabrowser.org/oma/group/KVKRSAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN18", "url": "https://www.orthodb.org/?gene=A0A8V0YN18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11471", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11471", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11471:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11471:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3371378", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371378", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5218900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69416", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69416", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75157", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75157", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQAHRSRAGSSPRAQSGPASAVFGCHMEDHTKRVQPVPLPAMQQNLNYMYPQIFWVDGCADASTSCHPASPVAPFPPPVPDRRKKPKSSKERSSVSFLVIFLLILLALTGAGLSMFQIFHLEKELAELRESVNADRIPPALEKLIGQESKPVKKEARKAAHLTGNPTQRNLPLEWEPVSGHAFTSGIQYRDQGLVINETGLYFVYSNVLFRGRHCDNEVLTHVVYKRNPASPGSHVLMEDKRINYCTKEKMWARKSYLGALFKLRERDSLYVNVSRIDLVNSEESKTFFGLFKL", "length": 295, "header": "tr|A0A8V0YN18-1|A0A8V0YN18_CHICK Isoform 1 of Tumor necrosis factor ligand superfamily member 6 OS=Gallus gallus OX=9031 GN=FASLG PE=3 SV=1 CANONICAL=A0A8V0YN18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18/entry", "sequence": { "sequence": "MMQAHRSRAGSSPRAQSGPASAVFGCHMEDHTKRVQPVPLPAMQQNLNYMYPQIFWVDGCADASTSCHPASPVAPFPPPVPDRRKKPKSSKERSSVSFLVIFLLILLALTGAGLSMFQIFHLEKELAELRESVNADRIPPALEKLIGQESKPVKKEARKAAHLTGNPTQRNLPLEWEPVSGHAFTSGIQYRDQGLVINETGLYFVYSNVLFRGRHCDNEVLTHVVYKRNPASPGSHVLMEDKRINYCTKEKMWARKSYLGALFKLRERDSLYVNVSRIDLVNSEESKTFFGLFKL", "length": 295, "header": "tr|A0A8V0YN18-1|A0A8V0YN18_CHICK Isoform 1 of Tumor necrosis factor ligand superfamily member 6 OS=Gallus gallus OX=9031 GN=FASLG PE=3 SV=1 CANONICAL=A0A8V0YN18-1" }, "locus": { "chromosome": "8", "start_pos": 4470146, "end_pos": 4467077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032642.1", "url": "https://www.ensembl.org/id/ENSGALT00010032642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019343.1", "url": "https://www.ensembl.org/id/ENSGALP00010019343.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of perforin, granzyme A and Fas ligand mRNA in caecal tissues upon Eimeria tenella infection of na\u00efve and immune chickens.", "journal": "Parasite immunology", "date": "2016-07", "authors": "Wattrang E, Magnusson S E, N\u00e4slund K, Thebo P, Hagstr\u00f6m \u00c5, Smith A L, Lund\u00e9n A", "evidence": [ { "database": "RefSeq", "id": "NP_001026730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026730" } ], "reference": [ { "type": "PubMed", "id": "27136454", "url": "https://glygen.org/publication/PubMed/27136454" } ] } ], "pathway": [ { "id": "gga:429064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429064", "resource": "KEGG Pathway" }, { "id": "R-GGA-3371378", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371378", "resource": "Reactome", "description": "Regulation by c-FLIP" }, { "id": "R-GGA-5218900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218900", "resource": "Reactome", "description": "CASP8 activity is inhibited" }, { "id": "R-GGA-69416", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69416", "resource": "Reactome", "description": "Dimerization of procaspase-8" }, { "id": "R-GGA-75157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75157", "resource": "Reactome", "description": "FasL/ CD95L signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UHU9-1", "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "FASLG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQQPLNYPYPQIFWVDSSATSPWASPGSVFPCPASVPGRPGQRRPPPPPPPPPPPPTLLPSRPLPPLPPPSLKKKRDHNAGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELTELRESASQRHTESSLEKQIGHPNLPSEKKELRKVAHLTGKPNSRSIPLEWEDTYGIALVSGVKYMKGSLVINDTGLYFVYSKVYFRGQYCNNQPLSHKVYTRNSRYPQDLVLMEGKMMNYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESKTFFGLYKL", "length": 282 }, "evidence": [ { "id": "A0A8V0YN18", "url": "https://omabrowser.org/oma/group/A0A8V0YN18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MKI9-1", "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "Faslg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQQPVNYGCPQIYWVDNSATSSWAPPGSVFPCPSSVPGRPDQRRPPPPPPPIPPPSQPPPSPPPPLPPMPPLKKRKDHSIDQWLPVIFFMVVAALVGLGLGMYQLFHLQKELAELRELTNQSLKVSSFEKQIYHPGQPSEKEEPRCVAHLTGNPSSRSVLLEWEDTYGTALISGVKYKKGGLVINVPGLYFVYSKVYFRGHSCTNQPLSHKVYMRNSKYLGDLVLMEEKKLNYCTPGQMWAHSSYLGAVFNLTSADHLYVNISQLSLINFDESKTFFGLYKL", "length": 282 }, "evidence": [ { "id": "A0A8V0YN18", "url": "https://omabrowser.org/oma/group/A0A8V0YN18/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P36940-1", "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "Faslg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQPVNYPCPQIYWVDSSATSPWAPPGSVFSCPSSGPRGPGQRRPPPPPPPPSPLPPPSQPPPLPPLSPLKKKDNIELWLPVIFFMVLVALVGMGLGMYQLFHLQKELAELREFTNHSLRVSSFEKQIANPSTPSETKKPRSVAHLTGNPRSRSIPLEWEDTYGTALISGVKYKKGGLVINEAGLYFVYSKVYFRGQSCNSQPLSHKVYMRNFKYPGDLVLMEEKKLNYCTTGQIWAHSSYLGAVFNLTVADHLYVNISQLSLINFEESKTFFGLYKL", "length": 278 }, "evidence": [ { "id": "A0A8V0YN18", "url": "https://omabrowser.org/oma/group/A0A8V0YN18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P41047-1", "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "Faslg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQPMNYPCPQIFWVDSSATSSWAPPGSVFPCPSCGPRGPDQRRPPPPPPPVSPLPPPSQPLPLPPLTPLKKKDHNTNLWLPVVFFMVLVALVGMGLGMYQLFHLQKELAELREFTNQSLKVSSFEKQIANPSTPSEKKEPRSVAHLTGNPHSRSIPLEWEDTYGTALISGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNQPLNHKVYMRNSKYPEDLVLMEEKRLNYCTTGQIWAHSSYLGAVFNLTSADHLYVNISQLSLINFEESKTFFGLYKL", "length": 279 }, "evidence": [ { "id": "A0A8V0YN18", "url": "https://omabrowser.org/oma/group/A0A8V0YN18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48023-1", "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "FASLG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL", "length": 281 }, "evidence": [ { "id": "A0A8V0YN18", "url": "https://omabrowser.org/oma/group/A0A8V0YN18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "positive regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001238", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell apoptotic process", "id": "GO:2000353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:0008625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "necroptotic signaling pathway", "id": "GO:0097527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "T cell apoptotic process", "id": "GO:0070231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070231", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylserine exposure on apoptotic cell surface", "id": "GO:1905782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" } ], "pmid": "" }, { "name": "cytoplasmic vesicle lumen", "id": "GO:0060205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060205", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN18", "url": 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"start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN18" }, { "id": "PS50049", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50049" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THD", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 295, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN20-1", "uniprot_ac": "A0A8V0YN20", "uniprot_id": "A0A8V0YN20_CHICK", "mass": { "chemical_mass": 90651.0, "monoisotopic_mass": 90651.0 }, "refseq": {}, "gene_names": [ { "name": "CDH22", "type": "recommended", "evidence": [ { "id": "A0A8V0YN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ] } ], "protein_names": [ { "name": "Cadherin-22", "type": "recommended", "evidence": [ { "id": "A0A8V0YN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20/entry#names_and_taxonomy" } ] }, { "name": "Pituitary and brain cadherin", "type": "synonym", "evidence": [ { "id": "A0A8V0YN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20#function" }, { "database": "UniProtKB", "id": "ARBA00057645", "url": "https://www.uniprot.org/uniprotkb/ARBA00057645#function" }, { "database": "UniProtKB", "id": "E1C3A7", "url": "https://www.uniprot.org/uniprotkb/E1C3A7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDH22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20", "locus": { "chromosome": "20", "start_pos": 10989369, "end_pos": 11026031, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016083", "url": "https://www.ensembl.org/id/ENSGALG00010016083" } ] } } ], "crossref": [ { "id": "A0A8V0YN20", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN20", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007211", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419305", "url": "https://www.ncbi.nlm.nih.gov/gene/419305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GAWAMHT", "url": "https://omabrowser.org/oma/group/GAWAMHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN20", "url": "https://www.orthodb.org/?gene=A0A8V0YN20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3A7", "url": "https://www.orthodb.org/?gene=E1C3A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3A7", "url": "https://www.uniprot.org/uniprotkb/E1C3A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3A7-1", "url": "https://www.uniprot.org/uniprotkb/E1C3A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKGLQGCCWTMLLLLCAIQELGAWAMHTATESPGLGQPGDPTLLASGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGSIKYTISGEGAGTIFLIDEITGDIHATERLDREQKTFYTLRAQARDRQTDQLLEPESEFIIKVQDINDSEPRFLEGPYIGSVAELSPIGTSVMQVMASDADDPTYGSSARIVYSVLEGEQHFTVDSKTGVIRTAVADLDRETQDRYEVVIRATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIIETAPVGTAIGRVKAEDSDVGENTDMTYQMKDEEGVEMFKVTTDSNTQEAVITVQKPLDYESKKVHTVVVEALNKFVDPRFVDLGTFRDQTIVRVSVLDVDEPPEFWPPSNTMEVQEDAHIGSIVGVVTALDPDTANHPVRYAIDRSTDTERIFDIDANTGAIVTGKVLDRETAGWHNITVLAMEADNHSQVSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFTLAPEATNNHHFSLLDVKDNTAAVHTQRVGFNRQEQDVYLLPILVVDSGPPALSSTGTLTIRVCGCDSTGAIQSCNSTAYAMSATLSPGALIALLVCVLILIVLVLLILTLKRHHKSHLTSEDDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFSEIKGGDGGGGPGEGGNPASERHALPQWVQSPDLDFSVFRDYICRKVEQADEDLSVPPYDSFQTYAFEGSDSPVPSLSSINTWSSGSEQDFSYLGGWGPRFRQLAALYAGRRGEHHPAPTRTHLRPTQRHPRSKLHATPQRKT", "length": 825, "header": "tr|A0A8V0YN20-1|A0A8V0YN20_CHICK Isoform 1 of Cadherin-22 OS=Gallus gallus OX=9031 GN=CDH22 PE=4 SV=1 CANONICAL=A0A8V0YN20-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20/entry", "sequence": { "sequence": "MAKGLQGCCWTMLLLLCAIQELGAWAMHTATESPGLGQPGDPTLLASGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGSIKYTISGEGAGTIFLIDEITGDIHATERLDREQKTFYTLRAQARDRQTDQLLEPESEFIIKVQDINDSEPRFLEGPYIGSVAELSPIGTSVMQVMASDADDPTYGSSARIVYSVLEGEQHFTVDSKTGVIRTAVADLDRETQDRYEVVIRATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIIETAPVGTAIGRVKAEDSDVGENTDMTYQMKDEEGVEMFKVTTDSNTQEAVITVQKPLDYESKKVHTVVVEALNKFVDPRFVDLGTFRDQTIVRVSVLDVDEPPEFWPPSNTMEVQEDAHIGSIVGVVTALDPDTANHPVRYAIDRSTDTERIFDIDANTGAIVTGKVLDRETAGWHNITVLAMEADNHSQVSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFTLAPEATNNHHFSLLDVKDNTAAVHTQRVGFNRQEQDVYLLPILVVDSGPPALSSTGTLTIRVCGCDSTGAIQSCNSTAYAMSATLSPGALIALLVCVLILIVLVLLILTLKRHHKSHLTSEDDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFSEIKGGDGGGGPGEGGNPASERHALPQWVQSPDLDFSVFRDYICRKVEQADEDLSVPPYDSFQTYAFEGSDSPVPSLSSINTWSSGSEQDFSYLGGWGPRFRQLAALYAGRRGEHHPAPTRTHLRPTQRHPRSKLHATPQRKT", "length": 825, "header": "tr|A0A8V0YN20-1|A0A8V0YN20_CHICK Isoform 1 of Cadherin-22 OS=Gallus gallus OX=9031 GN=CDH22 PE=4 SV=1 CANONICAL=A0A8V0YN20-1" }, "locus": { "chromosome": "20", "start_pos": 11025832, "end_pos": 10989693, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038684.1", "url": "https://www.ensembl.org/id/ENSGALT00010038684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022376.1", "url": "https://www.ensembl.org/id/ENSGALP00010022376.1" } ] } }, { "isoform_ac": "E1C3A7-1", "url": "https://www.uniprot.org/uniprotkb/E1C3A7/entry", "sequence": { "sequence": "MAKGLQGCCWTMLLLLCAIQELGAWAMHTATESPGLGQPGDPTLLASGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGSIKYTISGEGAGTIFLIDEITGDIHATERLDREQKTFYTLRAQARDRQTDQLLEPESEFIIKVQDINDSEPRFLEGPYIGSVAELSPIGTSVMQVMASDADDPTYGSSARIVYSVLEGEQHFTVDSKTGVIRTAVADLDRETQDRYEVVIRATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIIETAPVGTAIGRVKAEDSDVGENTDMTYQMKDEEGVEMFKVTTDSNTQEAVITVQKPLDYESKKVHTVVVEALNKFVDPRFVDLGTFRDQTIVRVSVLDVDEPPEFWPPSNTMEVQEDAHIGSIVGVVTALDPDTANHPVRYAIDRSTDTERIFDIDANTGAIVTGKVLDRETAGWHNITVLAMEADNHSQVSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFTLAPEATNNHHFSLLDVKDNTAAVHTQRVGFNRQEQDVYLLPILVVDSGPPALSSTGTLTIRVCGCDSTGAIQSCNSTAYAMSATLSPGALIALLVCVLILIVLVLLILTLKRHHKSHLTSEDDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFSEIKGGDGGGGPGEGGNPASERHALPQWVQSPDLDFSVFRDYICRKVEQADEDLSVPPYDSFQTYAFEGSDSPVPSLSSINTWSSGSEQDFSYLGGWGPRFRQLAALYAGRRGEEDSEES", "length": 802, "header": "tr|E1C3A7-1|A0A8V0YN20_CHICK Computationally mapped isoform of Cadherin-22 OS=Gallus gallus OX=9031 GN=CDH22 PE=4 SV=2 CANONICAL=A0A8V0YN20-1" }, "locus": { "chromosome": "20", "start_pos": 11025832, "end_pos": 10991822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038681.1", "url": "https://www.ensembl.org/id/ENSGALT00010038681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022374.1", "url": "https://www.ensembl.org/id/ENSGALP00010022374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1SC52-1", "protein_name": "Cadherin-22", "gene_name": "CDH22", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPRLDGRGLRAGAALSPALLLLLLLLLLPPPPQLPGPLWAAGTPAPSEPRAAQDGAPGTGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLREESGSGGHVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVVLEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFQPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRDSDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHLGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGAIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGSGGGGPGGDAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAGSLSSLHSGSSGSEQDFAFLSSWGPRFRPLAALYAGHRPDEEAPAS", "length": 825 }, "evidence": [ { "id": "A0A8V0YN20", "url": "https://omabrowser.org/oma/group/A0A8V0YN20/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q63315-1", "protein_name": "Cadherin-22", "gene_name": "Cdh22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPRPAGALRAGAALSPVLLLLLLLQLLGHLWAASTPAPSSLSPGTQQDNQLGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGTIKYTISGEGAGTIFLIDELTGDIHATERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLREESGSGGDAFKVTTDSDTQEAIIVVQKHLDFESQQVHTVVLEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRDSDLEQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEEPSNPHFSLLDIEDNTAAVHTQHVGFNRQEQDVFLLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLALLILTLRRHHKSHLSSDVDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDPGGGAASPPQAASSSERHSLPRGPSSPEPDFSVFRDFISRKVALADADLSVPPYDAFQTYAFEGAGSPAASLSSLHSGSTGSEQDFAFLRAWGPRFRPLAALYAGHRGDDEAPAS", "length": 813 }, "evidence": [ { "id": "A0A8V0YN20", "url": "https://omabrowser.org/oma/group/A0A8V0YN20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UJ99-1", "protein_name": "Cadherin-22", "gene_name": "CDH22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS", "length": 828 }, "evidence": [ { "id": "A0A8V0YN20", "url": "https://omabrowser.org/oma/group/A0A8V0YN20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WTP5-1", "protein_name": "Cadherin-22", "gene_name": "Cdh22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPRPEGALRAGAALSPVLLFLLLLPLLGHLWAASTPAPSSLSPGAQEDNQLGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGTIKYTISGEGAGTIFLIDELTGDIHATERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLREESGSGGDAFKVTTDSDTQEAIIVVQKHLDFESQQVHTVVLEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRDSDLEQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIEDNTAAVHTQHVGFNRQEQDVFLLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLALLILTLRRHHKSHLSSDVDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDPGGGAASPPQAASSSERHSLPRGPSSPEPDFSVFRDFISRKVALADADLSVPPYDAFQTYAFEGAGSPAASLSSLHSGSTGSEQDFAFLRAWGPRFRPLAALYAGHRGDDEAPAS", "length": 813 }, "evidence": [ { "id": "A0A8V0YN20", "url": "https://omabrowser.org/oma/group/A0A8V0YN20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN20" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 158, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 600, "end_pos": 602 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YN65-1", "uniprot_ac": "A0A8V0YN65", "uniprot_id": "A0A8V0YN65_CHICK", "mass": { "chemical_mass": 194405.0, "monoisotopic_mass": 194405.0 }, "refseq": {}, "gene_names": [ { "name": "KDM3B", "type": "recommended", "evidence": [ { "id": "A0A8V0YN65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65" } ] } ], "protein_names": [ { "name": "Lysine-specific demethylase", "type": "recommended", "evidence": [ { "id": "A0A8V0YN65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.65", "type": "synonym", "evidence": [ { "id": "A0A8V0YN65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65#function" }, { "database": "UniProtKB", "id": "RU369087", "url": "https://www.uniprot.org/uniprotkb/RU369087#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KDM3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65", "locus": { "chromosome": "13", "start_pos": 17808833, "end_pos": 17762644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014198", "url": "https://www.ensembl.org/id/ENSGALG00010014198" } ] } } ], "crossref": [ { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN65", "url": "https://www.orthodb.org/?gene=A0A8V0YN65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12549", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12549", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12549:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12549:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22987", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22987", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "60188", "url": "https://www.rhea-db.org/rhea/60188", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YN65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAANRANAGSPARGIVGERKEGGKTVLARCMPGLGRAALGGLERGSRSVGVWGPCRSVGSGRRRRRLLSGGGWRTWRPPPWESGSCCCWRRRRIFVEFDGCNWKQHAWVKVHAEEVIVLLLEGSLVWAPRNDPVLLQGARVSPKQWPALTFTPLVDKLGLGSVVPVEFLVDRHLRFLSDASGLRLFQMGTESQNQILQEQPLLRESVNSLFSDQKLQEIFSRVPYSIQGQRVKVYQPEDENSWLCGVVSHQDPITRLMEVSVTETGEIKSVDPRLIHVIMDNSSSSEGGGLKAAKSSKGKKKRESFEGKDGRRRKNVSDSGCDPATKKLKERGEVDGNGSDGGEASRGPWKGVSSSETGLDPRAKQLPSFVPQMNRNIRFATYTKENGRTLVVQDEPVGGDTPVPFTPFSSVAGQALLAGSGCKEAGKSLEQVGQGTVTSATTVSTTALTPTTVRISDTSLPAITGQEKLKTGRTQTQGENSRNSLSASTGFGISLPGASQSLAFGGGRSQSNGVATPESKPSGFIFGCSTGQEAQKDSDLSKNLFFQCMTQNLPSSNYFTVISESLSEDASSRDTFKQCTESVGAGVCKGKVLSADTQSGSSVERKLPVECMPTLTPAFSRSLLNTRPPDSHENLFLQPPKLSREEPSNPFLAFAEKTELSPFSGFASSQTGVSTPSTSVGHKTASGWPESITATDSLAKKKTLFITTDSSKMMSSTPGPAASVGVQSPSTAGNGRSSSPASNLIQPIEMPTLSSSPTEEKPAVGPGQQDNPLLKTFSNVFGRHPPGFFSSQAEFPQDNKAPFEAVKRFSLDERSLTSKQDSDSSTNSDLSDLSDSEEQLQAKACMKGIPDHLMVKLGPNAERNAELLLGKGKGKQAPKGRPRTAPLKVGQSVLKDMSKVRKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGILRVEGFLNPQQSDPDAMSLWIPSSSPAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKNRPRSETEEIGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCINRQNKSVLRPAVTNGMSQLPSVNPSASVSGNESTFSTGAGTAGVGQLEMDSVPKSEANDSRIEELAKTETSPISNTAETKTNRPLCSDTAPSSALHWLADLATQKAKEETKESGLLRSVLNKESHSPFGLDSFNSSTKVSPLTPKLFNSLLLGPVTSSNKAEGSSLRDLLHTGPGKLPQVPLDAGIPFPPVFSAASTGAKGKASLPNFLDHIIASVVENKKTSDAAKRASNLADTQRDVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSLEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIISKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGTHDDEVLKTIDEGDADDVTKQRIHEGREKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYDEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLKAHESKLARS", "length": 1774, "header": "tr|A0A8V0YN65-1|A0A8V0YN65_CHICK Isoform 1 of Lysine-specific demethylase OS=Gallus gallus OX=9031 GN=KDM3B PE=1 SV=1 CANONICAL=A0A8V0YN65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN65/entry", "sequence": { "sequence": 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"length": 1774, "header": "tr|A0A8V0YN65-1|A0A8V0YN65_CHICK Isoform 1 of Lysine-specific demethylase OS=Gallus gallus OX=9031 GN=KDM3B PE=1 SV=1 CANONICAL=A0A8V0YN65-1" }, "locus": { "chromosome": "13", "start_pos": 17807580, "end_pos": 17762836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034186.1", "url": "https://www.ensembl.org/id/ENSGALT00010034186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020082.1", "url": "https://www.ensembl.org/id/ENSGALP00010020082.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 718, "start_aa": "Thr", "end_pos": 718, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr718", "evidence": [ { "id": 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{ "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA8" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA8" } ], "pmid": "" }, { "name": "respiratory chain complex IV", "id": "GO:0045277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNB2-1", "uniprot_ac": "A0A8V0YNB2", "uniprot_id": "A0A8V0YNB2_CHICK", "mass": { "chemical_mass": 356640.0, "monoisotopic_mass": 356640.0 }, "refseq": { "ac": "XP_015140065", "name": "DNA polymerase zeta catalytic subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140065" }, "gene_names": [ { "name": "REV3L", "type": "recommended", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ] }, { "name": "REV3L", "type": "synonym", "evidence": [ { "id": "XP_015140065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140065" } ] } ], "protein_names": [ { "name": "DNA polymerase zeta catalytic subunit", "type": "recommended", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.7", "type": "synonym", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2/entry#names_and_taxonomy" } ] }, { "name": "DNA polymerase zeta catalytic subunit", "type": "synonym", "evidence": [ { "id": "XP_015140065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140065" } ] }, { "name": "Protein reversionless 3-like", "type": "synonym", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140065.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140065" } ] }, { "annotation": "Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2#function" }, { "database": "UniProtKB", "id": "ARBA00059263", "url": "https://www.uniprot.org/uniprotkb/ARBA00059263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REV3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2", "locus": { "chromosome": "3", "start_pos": 65889836, "end_pos": 65774757, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013664", "url": "https://www.ensembl.org/id/ENSGALG00010013664" } ] } } ], "crossref": [ { "id": "cd05534", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05534", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05778", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05778", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428622", "url": "https://www.ncbi.nlm.nih.gov/gene/428622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032757", "database": "InterPro", "categories": [ 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"https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015140065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSVRIVTADYYMGSPLPGLDPCQSHFREAPTRRVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGFGQHPEHYLRQVAFSIDRALNVALGNPSSTIQHVFKVSLVSGMPFYGYHEKERQFMKIYLYNPAMVKRVCELLQGGAIMNKSYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSDTSGGSKHDRINSAANSNSASFIEWEEDEIPSSLMLKGVEPQSTCELEVDAVAADILNQLDIEAQIGRNPGLQAIWEDEKQRRREKCESSQIKTPESQDRGFVPATESEKYFQKRLKEILKQNDFSVTLSGSVDYSNGSEEFSAELTLHSEVLSPETFQCTPANMVEVHEDKKMNKESNRMHTDKEEEALINEEAILNIVENSQSFHRLSQKLCQTTVFLDSADEAMIDVLAGLESDGYQMEHHKALSHHRSLGSCRNSQNSDDEENEPQCEKEEMELSLIMSQRWDSSIEEPGPKRRSAGKNMHRSSTEEDSSSEEEMEWSGSNMLLTNLSIPQLDGTADENGDNPLNNESSRTHSSVIATSKMSVKTSIFHKDAATLEPPSSAKITFQCKHTSALSNHVLNNEDLVEDLSQPNTETRPELSVHSLTKESTYTAKYPTSFSNSTHAENSHKESNKKDTLPVPSCENNIFEYEDDISSVSRQIPSRKYTSIRKTEKDVSFMHMGRHIGDSILNKNSFNFSDLSHSGHSKGKISSELNEKASSASINSFFPATVTENCELVSCSGGSRTVVHSLENNTDEGGLNKLKIRYEEFQEHKAEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLAPVTYKLQQGNKQSRLKLNKKKYSFINHQEPATVSDVVSVKESCYTQGNACSNIPDKDSALPSDLVQVPLESFENKMPTSTAHCTDCQIGDGSLETEQSFGLCGNKYTLRTKRKVNYETEDSESSFVAHNSKINLPQPIESVESLDGSQKSRKRRRLSKKLPPVIIKYIIINRFRGRKNMLVKLGKVDSSEERVVLTEEKMNLYRKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHKRKAKHKSTKKKAGKLQRTGSKNNIKRTLSFRKRTHTILSPPSPSYNAEAEDCDYNYSDVMSKLGFLSERSTSPVNTSPPRCWSPTDPKAEEILTNLDREALHSRGNMYNNRTVNSNVGKNSRAKTQVKKCKKKFASPTVSTKKKKKMNQSDKTADDGKKKPRTKQRQKTTEKMSSRKRMVFKDEKGNNQSATEVKFVLKHQDLPEMSYNSQPLHHRRDGPLPGFTAGYLPSAPFPSAADTQGNSSDCFHSLMELDKPLDAQCLPAPREDPHSSLTSSPVASGREVLKVSSQRPRTQSAVFRMKESALVKNIFDSSNHSTQVTQNVCISKDKTFVKAEEIKNLQNRYLPSAGKLSEARESSDSTKMDQLHSTSYLHCKDNNQQQIFCIPEASKHSDPSSSVLKSSEESPGPLQLPKNCFVTSLKSPVKQLNWDQKQRGFLLEMSHFKPETVKQKSPSETTTQPKPISHYKNRTIVAPSAFSEGQSGLAVLKELLQKRQQKAQNANVTQEPLPVKTQLSRGTPCPLEQNKAIKRSRSATPRKPRAPRNTKPKEKTPKLSKMESLSQQVTGHVDHSVSDDSPIFFSDPGFESCYSLEDSLSPDHNYNFDINTIGQTGFCSFYSASQFVPADQNLPQKFLSDAVQDLGSVQTTENDFLCRNDQKTDEEKQHSSSTSKWIRPGSLSPELFEKTSLDSNENHCHSQRRKNVHPSTSRSNSIDTSCTQETEVCLNEKFKLTRNAVNKERFLNLPQPTSSDWIQSHIRKETTFGPCQPLDSVNTSFTSVLSSPDGELIDAASEDLELYVSRNNEALTPTPDSSPRSTSSPSQSKNGSFTPRTAHILKPLMSPPSREEIMATLLDHDLTETVYQEPFCSNPSDAPEKPREIGGRLLTVETRLPNDLLEFEGDFSLEGLRLWKTAFSAMTEGPRPGSPPRYDHSAANKKEGNSHKTSKDKKIVIMPCKCAPSQQQVQIWLHAKEEYEHFKRLPKNHPAELEKAAENFSSTVLSGEKSSEVVKAAKDLNLSSLEDGRPIVPTKDSPASVADPTKAQTKETCDKSVSTIGASINIKSDIDSSETTSESKTLTASALERDKEEEEEDYYVSYSSPDSPVLPPWQQVASPDPKQSNLEDAEWKSQDVILSSVKENDVAPVGSTQNSPSTQEDIKMAFDTSPLLLSVDPGNSESICLHSTPITQRKSHDGIHEVLGFTPLSTEPKARKLCHKRGINTDGLRRVLLTTQMKNQFAALGAPKRETSQIEGPSLNNTYGFKVSVQNLQEAKSLHEVQHLTLISMELHARTRRDLEPDPEFDPICALFYCVSSDTALPNTDKKEITGAIVIDSDRTLSSQGSRDQAPLLTRSGITGLEVSYATDERTLFQEVVNIVKRYDPDILLGYEVQMHSWGYLLQRAAALNVDLCQMISRVPDDNKENRFAAELDEYGSDTMSEINIVGRIILNIWRMMRNEVNLMNYTFENVGFHVLHQRFPLFTFRVLSDWFDNKADVYRWKMVDHYVSRVHGNLQLLQKLDLIDRTSEMARLFGIQFLHVLTRGSQYRVESMMLRVAKPMNYIPVTPSIQQRAQMKAPQCVPLIMEPESRFYSNAVLVLDFQSLYPSIVIAYNYCFSTCLGPVENLGKYDAFKFGCTSLRVPPDLLYQIRHDITVSPSGVAFVKPSVRKGVLPRMLEEILKTRIMVKQSMKAYKHDKAITRMLEARQLGLKYIANFTYGYTAANFSGRMPCIELGDSIVHKARETLERAIKLVNDTKKWGAHVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILECSIKLLFETRDISQIKQYVQNQCMKLLEGKASIQDFIFAKEYRGSSAYKPGSCVPALEITRRMLAYDRRSEPRVGERVPYVIVYGMPGLPLIQLVRRPTEVLQDPSLRLNATYYITKQILPPLARVFSLIGIDVFSWYHELPRIQKTASTARSELEGRKGTISQYFTTLHCPVCDELTQYGICTKCRSQPQHVAVILNQEIRELERKQDQLVKICKNCTGCFDRQIPCVSLNCPVLFKLSRVSRELLKAPYLRQLLDQF", "length": 3167, "header": "tr|A0A8V0YNB2-1|A0A8V0YNB2_CHICK Isoform 1 of DNA polymerase zeta catalytic subunit OS=Gallus gallus OX=9031 GN=REV3L PE=3 SV=1 CANONICAL=A0A8V0YNB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2/entry", "sequence": { "sequence": "MFSVRIVTADYYMGSPLPGLDPCQSHFREAPTRRVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGFGQHPEHYLRQVAFSIDRALNVALGNPSSTIQHVFKVSLVSGMPFYGYHEKERQFMKIYLYNPAMVKRVCELLQGGAIMNKSYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSDTSGGSKHDRINSAANSNSASFIEWEEDEIPSSLMLKGVEPQSTCELEVDAVAADILNQLDIEAQIGRNPGLQAIWEDEKQRRREKCESSQIKTPESQDRGFVPATESEKYFQKRLKEILKQNDFSVTLSGSVDYSNGSEEFSAELTLHSEVLSPETFQCTPANMVEVHEDKKMNKESNRMHTDKEEEALINEEAILNIVENSQSFHRLSQKLCQTTVFLDSADEAMIDVLAGLESDGYQMEHHKALSHHRSLGSCRNSQNSDDEENEPQCEKEEMELSLIMSQRWDSSIEEPGPKRRSAGKNMHRSSTEEDSSSEEEMEWSGSNMLLTNLSIPQLDGTADENGDNPLNNESSRTHSSVIATSKMSVKTSIFHKDAATLEPPSSAKITFQCKHTSALSNHVLNNEDLVEDLSQPNTETRPELSVHSLTKESTYTAKYPTSFSNSTHAENSHKESNKKDTLPVPSCENNIFEYEDDISSVSRQIPSRKYTSIRKTEKDVSFMHMGRHIGDSILNKNSFNFSDLSHSGHSKGKISSELNEKASSASINSFFPATVTENCELVSCSGGSRTVVHSLENNTDEGGLNKLKIRYEEFQEHKAEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLAPVTYKLQQGNKQSRLKLNKKKYSFINHQEPATVSDVVSVKESCYTQGNACSNIPDKDSALPSDLVQVPLESFENKMPTSTAHCTDCQIGDGSLETEQSFGLCGNKYTLRTKRKVNYETEDSESSFVAHNSKINLPQPIESVESLDGSQKSRKRRRLSKKLPPVIIKYIIINRFRGRKNMLVKLGKVDSSEERVVLTEEKMNLYRKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHKRKAKHKSTKKKAGKLQRTGSKNNIKRTLSFRKRTHTILSPPSPSYNAEAEDCDYNYSDVMSKLGFLSERSTSPVNTSPPRCWSPTDPKAEEILTNLDREALHSRGNMYNNRTVNSNVGKNSRAKTQVKKCKKKFASPTVSTKKKKKMNQSDKTADDGKKKPRTKQRQKTTEKMSSRKRMVFKDEKGNNQSATEVKFVLKHQDLPEMSYNSQPLHHRRDGPLPGFTAGYLPSAPFPSAADTQGNSSDCFHSLMELDKPLDAQCLPAPREDPHSSLTSSPVASGREVLKVSSQRPRTQSAVFRMKESALVKNIFDSSNHSTQVTQNVCISKDKTFVKAEEIKNLQNRYLPSAGKLSEARESSDSTKMDQLHSTSYLHCKDNNQQQIFCIPEASKHSDPSSSVLKSSEESPGPLQLPKNCFVTSLKSPVKQLNWDQKQRGFLLEMSHFKPETVKQKSPSETTTQPKPISHYKNRTIVAPSAFSEGQSGLAVLKELLQKRQQKAQNANVTQEPLPVKTQLSRGTPCPLEQNKAIKRSRSATPRKPRAPRNTKPKEKTPKLSKMESLSQQVTGHVDHSVSDDSPIFFSDPGFESCYSLEDSLSPDHNYNFDINTIGQTGFCSFYSASQFVPADQNLPQKFLSDAVQDLGSVQTTENDFLCRNDQKTDEEKQHSSSTSKWIRPGSLSPELFEKTSLDSNENHCHSQRRKNVHPSTSRSNSIDTSCTQETEVCLNEKFKLTRNAVNKERFLNLPQPTSSDWIQSHIRKETTFGPCQPLDSVNTSFTSVLSSPDGELIDAASEDLELYVSRNNEALTPTPDSSPRSTSSPSQSKNGSFTPRTAHILKPLMSPPSREEIMATLLDHDLTETVYQEPFCSNPSDAPEKPREIGGRLLTVETRLPNDLLEFEGDFSLEGLRLWKTAFSAMTEGPRPGSPPRYDHSAANKKEGNSHKTSKDKKIVIMPCKCAPSQQQVQIWLHAKEEYEHFKRLPKNHPAELEKAAENFSSTVLSGEKSSEVVKAAKDLNLSSLEDGRPIVPTKDSPASVADPTKAQTKETCDKSVSTIGASINIKSDIDSSETTSESKTLTASALERDKEEEEEDYYVSYSSPDSPVLPPWQQVASPDPKQSNLEDAEWKSQDVILSSVKENDVAPVGSTQNSPSTQEDIKMAFDTSPLLLSVDPGNSESICLHSTPITQRKSHDGIHEVLGFTPLSTEPKARKLCHKRGINTDGLRRVLLTTQMKNQFAALGAPKRETSQIEGPSLNNTYGFKVSVQNLQEAKSLHEVQHLTLISMELHARTRRDLEPDPEFDPICALFYCVSSDTALPNTDKKEITGAIVIDSDRTLSSQGSRDQAPLLTRSGITGLEVSYATDERTLFQEVVNIVKRYDPDILLGYEVQMHSWGYLLQRAAALNVDLCQMISRVPDDNKENRFAAELDEYGSDTMSEINIVGRIILNIWRMMRNEVNLMNYTFENVGFHVLHQRFPLFTFRVLSDWFDNKADVYRWKMVDHYVSRVHGNLQLLQKLDLIDRTSEMARLFGIQFLHVLTRGSQYRVESMMLRVAKPMNYIPVTPSIQQRAQMKAPQCVPLIMEPESRFYSNAVLVLDFQSLYPSIVIAYNYCFSTCLGPVENLGKYDAFKFGCTSLRVPPDLLYQIRHDITVSPSGVAFVKPSVRKGVLPRMLEEILKTRIMVKQSMKAYKHDKAITRMLEARQLGLKYIANFTYGYTAANFSGRMPCIELGDSIVHKARETLERAIKLVNDTKKWGAHVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILECSIKLLFETRDISQIKQYVQNQCMKLLEGKASIQDFIFAKEYRGSSAYKPGSCVPALEITRRMLAYDRRSEPRVGERVPYVIVYGMPGLPLIQLVRRPTEVLQDPSLRLNATYYITKQILPPLARVFSLIGIDVFSWYHELPRIQKTASTARSELEGRKGTISQYFTTLHCPVCDELTQYGICTKCRSQPQHVAVILNQEIRELERKQDQLVKICKNCTGCFDRQIPCVSLNCPVLFKLSRVSRELLKAPYLRQLLDQF", "length": 3167, "header": "tr|A0A8V0YNB2-1|A0A8V0YNB2_CHICK Isoform 1 of DNA polymerase zeta catalytic subunit OS=Gallus gallus OX=9031 GN=REV3L PE=3 SV=1 CANONICAL=A0A8V0YNB2-1" }, "locus": { "chromosome": "3", "start_pos": 65888825, "end_pos": 65774841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032848.1", "url": "https://www.ensembl.org/id/ENSGALT00010032848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019452.1", "url": "https://www.ensembl.org/id/ENSGALP00010019452.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1864, "start_aa": "Thr", "end_pos": 1864, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1864", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2617, "start_aa": "Thr", "end_pos": 2617, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2617", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428622", "resource": "KEGG Pathway" }, { "id": "R-GGA-110312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110312", "resource": "Reactome", "description": "Translesion synthesis by REV1" }, { "id": "R-GGA-5655862", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655862", "resource": "Reactome", "description": "Translesion synthesis by POLK" }, { "id": "R-GGA-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-GGA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LLY6-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "Rev3l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSVRIVTADYYMASPLRGLDICQSPLTQLPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDTSHATGSFKDQLSGNCAAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNESSQITQPESQDCRFVPATESEKLFQKRLQEILKQNDFSVTLSGSVDYSNGSQEFSAELTLHSEILSPEMLPCTPANMIEVHKDTDLSKGNTRQKVEEALINEEAILNLMENSQTFQPLTQRLSETPAFMDSSPDEALVHLLAGLESDGYQGEKNRMPLPCHSFGDSQNPQNSDDEENAPQIEKEEMELSLVMSQRWDNDIEEHCAKKRSLCRNAHRSSTEDDDSSSEEEMEWSDNSLLFANLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVRPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKEDLIEDLSQPNNTEKGRDNSITFTNESTYSMKHSGSLSSTVHSDNSHKEICKKDKSLPVSSCESSIFDYEEDIPSVTRQIPSRKYTNMRKIEKDAPFIHVNRHTSENTLGKNSFNFPDLSHSKTKLSSEGIEKGNSTSFNSIFPSSLAESCDMLSSSGENRTMVHSLDSITDESGLNKLKIRYEEFQEHKMEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLSPVTYKLQSGSKPARLKLNKKKLIGHQETSTKSSDTGTTKDSCTSNNPYSSTSEKDNTSSSDLIKATHGTFENKASTENFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEESESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNSENIKRTLSFRKKRTHAILSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEILAAAEKESMLFKSPNAYNTKTVNPRVGKASRVKAQAKKSKARLANPSVVTKNRNRRSQTNKLVDNGKKKPRAKQKQRTNEKGTSRKHIAATDEKIKPQSEVEAKLAFNHQNMSGLTNSPGTQGLFKQKEMSQTGPAVDHPLSTCQPTGLNTQQKLSNCFSSFLESRKSMDLQTFPSSRDDLHSSVVHSSIGPGISKINIQRSHNQSAMFTGKESTLIQKSIFDLSNHLSQVAQSTQIPSRVMSPKTEESANIQKNCVSSMGKLNEYRSSLESKPEQVCAPNFLHCKDSQQQTVCMSEQPKHSETCSPGNAASEEGQAPNCFVTSLRSPIKQIAWEQKHRGFVLDMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQSANVIQDSTSSNQPDKNISVSVEHKKANKRTRVVASPRKPRTPRRTKPKEQTSRCLKVDPLNLQTSGQLDNSLSDDSPVLFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDKQSCSEEKHHVSDSSPWIRTSTLNPELFEKSSTDNNENHRHSQWKNSFHPLTSRSNSIMESFCVQQAEGCLNEKSRLNRSSMSKEVFLGLPQASSSDWIKGHNRKEMEQSLDSVNSSFTTILSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSASSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSETIYQEPFCSNPSDVPERPREIGGQLLMVETRLPNDLVEFEGDFSLEGLRLWKTAFSAMTQSPRPGSPLRNGQAVVNKGSSNSHKMVEDKKIVIMPCKYAPSRQLVQAWLQAKEEYERSKKLPKTELTGVIKSAENVSHLVNPGDAPAVSPQMDACPHTLSTTAHTKEEVTKAHIALQAPTTGCGQIVSASQTLLPVASAAVPEEDEGDDNYVSYSSPDSPGIPPWQQATSPDFKALNGDDRHSSPVEELCSLAVENFLKPIKDSIPKSPCSDSREPQVISPINARARTGKCDPLCLHSTPVMQRKFLEKLPEVTGLSPLSVEPKTQKLCNKKGSDAESLRRVLLTTQMKNQFAAVNTPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRYQTPLLIRSGITGLEITYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRFAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYEEFKFGCTSLRVPPDLLYQIRHDITVSPNGVAFVKPSIRKGVLPRMLEEILKTRFMVKQSMKAYKQDRALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILECSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLTYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPSEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIQKATSSSRSELEGRKGTISQYFTTLHCPVCDDLTQHGICSKCRSQPQHVAVILNQEIRELERKQEQLVKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF", "length": 3128 }, "evidence": [ { "id": "A0A8V0YNB2", "url": "https://omabrowser.org/oma/group/A0A8V0YNB2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BPY8-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "REV3L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFSVRIVTADYYMASPLQGLDICQSPLTQAPVKKVPVVRIFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSVVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSDPLHLTGSCKDRLPGKNSLTGTLFRWEEGEIPSSLILEGVEPQSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQISQPESQDRRFVPATESEKKFQKRLQEILKENNFSVTLSGSVDYSDGSQEFSAELTLHSEVLSHEILPCTPANMVEVHKDSELSKGHTRPKVEEALINEEAILNLMENSQTFQPLTQRLSESRVFLDSSPDEALVHLLAGLENDGYHRGRNRMPSPCRSFGNSKNPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEHCAKKRSLCRNTHRSSTEEDDSSSEEEMEWSNNSLLLANLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVKPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKEDLIEDLSQPSKLEKSLDHSVTSFTNESTYSMKYPGSLSSSVHPENSHKESGKKDVLPVSSCESSTFDYEDNIPPVTRQIPSRKYTNIRKIDKDAPFIHMSRHTNESTLGKNSLNFSDLNHSKSKLSSEGNEKGNSTALNSLFPSSLNENCELLSCSGENRTMMHSLDSIADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLSPVTYKLQPGNKQSRLKMNKKKLSGHQETSTKTAETGSSKDNYIQNNPCNSNNSEKDNVLASDLIKVTRGTFENKTSTDSFVDCHFGEGTLETEQSFGLYGNKYTLRAKRKVNYENEDNESSFVTHSSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGRQQRTSSENIRRTLSFRKKRSHAILSPPSPSYNAETEDCDSNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAADKEAMLFKGPNVYNSKTVNSRIGKNSRARMQVKKSKTKLVNPSTVSKKRNKRNQTNKLVDDGKKKPRAKQKQKTNEKSTPRKHTTLKEEKLKSQAGTEVKFVLKHQNGPETADNSGGSQLLFKQKDVSLMGSAIDHPLSAPIPTGIHAQQNLSGCFSSFLESKKPVDLQAFPSSRDDVNSSVVCSSLGPGISKINVQRSHCQNTMFTLKESSLIQKNIFDLSNHLSQVAQSTQMSSGIMSPKIEENANIQKSYLSSLGKLNEYRNSLESKPDQTYAPNFLHCKDSQQQIVCMAERSKHSETCSPGNAASEESQMPNNCFITSLRSPIKQIAWEQKQRGFILDMSNFKPERVKQKPLSEAVSQTKALSQCRNRNMSTPSAFGEGQSGLAVLKELLQKRQQKAQNGNSIQDPLSNKQQPNKNISVSLEHNKSVKRTRSVTSPRKPRTPRSTKPKEKIPKLLKVDSLNLQNSGQLDNSLSDDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQTVEKTEFLSHDNQKCDEDKHHASDSTAWIRSGTLSPELFEKSPIDSNENHRNNQWKNTFHPLTSRSNSIMETFCIQQSENCLNEKSRLNRSSISKEVFLSLSQPGSSDWIQSHTRKEMGQSLDAVNTSFTTILSSPDGELVDAASEDLELYVSRNTDVLTPTPDSSPRSTSSPSQSKNGSFTPRTAHILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPPRNGQAVVNKGSSNNRKMAEDKKIVIMPCKCAPSRQLVQAWLQAKEEYERSKKLSKTEPTRVVKSAEDFSSSVNPDDRPVAPPKMDTTPHTLPTTAHTKEDVDNSQIALQAPTTECHQTASESQTLPLVASAGDAEKDQDDDDDYYISYSSPDSPAIPPWQQAASPDSKTLNGDERPSSPVGDLHSLTIENLLKPVKDGVQKSPCTESQEPLVISPVNVRTRTEICESLCLHSTPIIQRKLERLPEATGLSPLSTEPKIQKLSHKKGSNTDALRRVLLTQAKNQFAAVNTPKKETSQIDGPSLNNTYGFKVSIQNLEEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTDKTELTGVIVIDKDKTVSSQDIRYQTPLLIRSGITGLQVTYAADEKTLFQEIANIIKRYDPDILIGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKTENRFAAERDEYGSDVMSEINIVGRITLNLWRIMRNEVALNNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYISRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGIAFVKPSVRKGVLPRMLEEILKTRLMVKRSMKAYKQDRVLSRMLDARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSLFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSASYKPGACVPALELTRKMLTYDRRSEPRVGERVPYVIIYGAPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIQKATSSSRSELEGRKGTIAQYFTTLHCPVCDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQERLVKICKNCTGCFDRHIPCVSLNCPVLYKLSRVNRELSKAPYLRQLLDQF", "length": 3133 }, "evidence": [ { "id": "A0A8V0YNB2", "url": "https://omabrowser.org/oma/group/A0A8V0YNB2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M8G6-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "Rev3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSVRIVTADYYMASPLPGLDICQSPLTQHPVKKVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGYGQQPERYLSQMALSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDASHATGLFKPQLSGNSPAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNENSQISQPESQDCRLVPATESEKIFQKRLQEILKQNDFSVRTLSGSVDYSSGSQEFSAELTLHSEILSPEMLPCSPANMIEVHRDNDWSKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMDSSPDESLVHLLAGLESDGYQGEKNRMPLPRHTFGESQNPQNSDDEENAPQMEKEEMELSVLMSQRWDSDTEEQCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSVFHKDAATLEPPSSAKITFQCKHTSALSSHGLNKDDLIEGLSQPNNTEKGRDSSVTFTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVPSCESSVFDYEEDIPSVTRQAPSRKYSNMRKIEKDAPFIHANRHTSESTLGKNSFNFADLNHSKNKLSSEGNERGNSTALNSVFPSSLAESCDLLSSSGENRSVAHSLDSITDESGRSKLKIRYEEFQEHKMERPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGSKTSRLKLNKKKLISLQETSTKSSETGAAKDSCTHNHPYSGTPEKESGLSSDLIKATHGTFENKTPTEHFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKRKPGKQHRASSENIKRTLSFRKKRTHAVLSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPVNSSPPRCWSPTDPRAEEIMAAAEKESVLFKGPNVCNTKTVSPRVGKASRARAQVKKSKARLAKSSVVTNKRNKRNQTNQLVDNGKKKPRAKQKQRANEKGISRKPVIPTDETTKPPSEAELTPSQRSVPELTSSSGIHTLSKQKEMTQTGPAMDHPLPPCQPTGINAQQRLSNCFSSFLESRKSVQFPTFPSSRGDSRSSVYSSIGPGVSKVNTQRSHSQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQLCSGIISPKTEESSNTQKNCGSSIGKLNEYRSSLESKPEKVCAPNFLHCRDSQQQTVNVSEQSKPSETCSPGNAASEESQTPNCFVTSLRSPIKQITWEQRQRGCILEMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQTTNVQDSASSHQPDKDISVSAEHKKTNKRTRAVASPRKPRAPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSLYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDRQSCTEEKHHVSDSGPWVRASTLNPELFEKVGIDNNENHRHSQWKTSFHPLTSHSNSIMESFCVQQAESCLPEKSRLNRSSVSKEVFLSLPQASSSDWIQGHNGKEIEQSLDSANTSFTTVLSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGPAVVNKESSNSHKTVEDKKIVIMPCRYAPSRQLVQAWLQAKEEYVRSKRLPRTESTPVIKSADNVSPSLNPGDTRAVAPQMDTCPHTLSSTAHAKEEVCQSQIALQTSRTGCGQTVSASQTLLPAASAAVPEEEEEEEEEEEEEEEDENGYVSYSSPDSPGIPPWQQAASPDFRALNGEHRCSSPVEELCSRAVENFLKPIKDGIQKASCCESQVISPIHARTRTEKCEPLCLHSTPVMPRKFLEKLPEATGLSPLSVEPKTQKLYNKKGSDTDHLRRVLLTTQVENQFAAVNTPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRCQTPLLIRSGVTGLEVTYAADEKALFQEVTNIMKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYRQDRALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIVYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKATSSSRSDLEGRKGTISQYFTTLHCPVCDGLTQHGICSQCRSQPQHVAIILNQEIRELERQQEQLVKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF", "length": 3133 }, "evidence": [ { "id": "A0A8V0YNB2", "url": "https://omabrowser.org/oma/group/A0A8V0YNB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60673-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "REV3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSNTLHATGSCKNHLSGNSLADTLFRWEQDEIPSSLILEGVEPQSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQMSQPESQDHRFVPATESEKKFQKRLQEILKQNDFSVTLSGSVDYSDGSQEFSAELTLHSEVLSPEMLQCTPANMVEVHKDKESSKGHTRHKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFMDSSPDEALVHLLAGLESDGYRGERNRMPSPCRSFGNNKYPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEHCAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVKPSIFHKDAATLEPSSSAKITFQCKHTSALSSHVLNKEDLIEDLSQTNKNTEKGLDNSVTSFTNESTYSMKYPGSLSSTVHSENSHKENSKKEILPVSSCESSIFDYEEDIPSVTRQVPSRKYTNIRKIEKDSPFIHMHRHPNENTLGKNSFNFSDLNHSKNKVSSEGNEKGNSTALSSLFPSSFTENCELLSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGNKPSRLKLNKRKLAGHQETSTKSSETGSTKDNFIQNNPCNSNPEKDNALASDLTKTTRGAFENKTPTDGFIDCHFGDGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNNENIKRTLSFRKKRSHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKEAMLFKGPNVYKKTVNSRIGKTSRARAQIKKSKAKLANPSIVTKKRNKRNQTNKLVDDGKKKPRAKQKTNEKGTSRKHTTLKDEKIKSQSGAEVKFVLKHQNVSEFASSSGGSQLLFKQKDMPLMGSAVDHPLSASLPTGINAQQKLSGCFSSFLESKKSVDLQTFPSSRDDLHPSVVCNSIGPGVSKINVQRPHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSGMSSKIEDNANNIQRNYLSSIGKLSEYRNSLESKLDQAYTPNFLHCKDSQQQIVCIAEQSKHSETCSPGNTASEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKPRSLSEAISQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTTQDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPRKPRTPRSTKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHTTDSASWIRSGTLSPEIFEKSTIDSNENRRHNQWKNSFHPLTTRSNSIMDSFCVQQAEDCLSEKSRLNRSSVSKEVFLSLPQPNNSDWIQGHTRKEMGQSLDSANTSFTAILSSPDGELVDVACEDLELYVSRNNDMLTPTPDSSPRSTSSPSQSKNGSFTPRTANILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPREIGGRLLMVETRLANDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRSGQGVVNKGSSNSPKMVEDKKIVIMPCKCAPSRQLVQVWLQAKEEYERSKKLPKTKPTGVVKSAENFSSSVNPDDKPVVPPKMDVSPCILPTTAHTKEDVDNSQIALQAPTTGCSQTASESQMLPPVASASDPEKDEDDDDNYYISYSSPDSPVIPPWQQPISPDSKALNGDDRPSSPVEELPSLAFENFLKPIKDGIQKSPCSEPQEPLVISPINTRARTGKCESLCFHSTPIIQRKLLERLPEAPGLSPLSTEPKTQKLSNKKGSNTDTLRRVLLTQAKNQFAAVNTPQKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANIIKRYDPDILLGYEIQMHSWGYLLQRAAALSIDLCRMISRVPDDKIENRFAAERDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGACVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIHKATSSSRSEPEGRKGTISQYFTTLHCPVCDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF", "length": 3130 }, "evidence": [ { "id": "A0A8V0YNB2", "url": "https://omabrowser.org/oma/group/A0A8V0YNB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61493-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "Rev3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 3122 }, "evidence": [ { "id": "A0A8V0YNB2", "url": "https://omabrowser.org/oma/group/A0A8V0YNB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "zeta DNA polymerase complex", "id": "GO:0016035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1296, "end_pos": 1298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1523, "end_pos": 1525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1557, "end_pos": 1559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1828, "end_pos": 1830, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1880, "end_pos": 1882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2049, "end_pos": 2051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2071, "end_pos": 2073, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2310, "end_pos": 2312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2515, "end_pos": 2517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2766, "end_pos": 2768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2775, "end_pos": 2777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2805, "end_pos": 2807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3018, "end_pos": 3020, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3125, "end_pos": 3127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z8P6-1", "A0A8V0XWC6-1", "Q92076-1", "A0A8V0ZUF2-1", "A0A8V0ZBR9-1", "P36195-1", "A0A8V0X4G3-1", "A0A8V0X331-1", "P10399-1", "A0A8V1A4V3-1", "A0A3Q2TTB3-1", "A0A8V0YNB2-1", "A0A8V0XWS0-1", "A0A8V0Y2U3-1", "A0A8V0Z9E4-1" ], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] }, { "id": "R-GGA-110311", "name": "POLZ extends translesion synthesis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-110311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110311" } ] }, { "id": "R-GGA-110322", "name": "Formation of Pol zeta complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-110322", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110322" } ] }, { "id": "R-GGA-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5652151", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5652151" } ] }, { "id": "R-GGA-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y2U3-1", "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5655835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655835" } ] }, { "id": "R-GGA-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y2U3-1", "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5655892", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655892" } ] }, { "id": "R-GGA-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-GGA-3006726" ], "enzyme_list": [ "A0A8V0Y2U3-1", "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5655965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655965" } ] }, { "id": "R-GGA-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5656148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656148" } ] }, { "id": "R-GGA-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNB2-1" ], "evidence": [ { "id": "R-GGA-5656158", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656158" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-3006726", "participant_name": "REV1 [nucleoplasm]", "crossref": [ { "id": "A0A8V0YTN6", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010022100", "database": "ENSEMBL", "url": "" }, { "id": "NP_001025982.2", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010038278", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010015877", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2TTB3", "gene_name": "PRIMPOL", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.102", "activity": "ssDNA + n dNTP = ssDNA/pppdN(pdN)n-1 hybrid + (n-1) diphosphate.", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.102", "activity": "", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q2TTB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTB3" } ] } ] }, { "uniprot_ac": "A0A8V0X331", "gene_name": "POLD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0X331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X331" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0X331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X331" } ] } ] }, { "uniprot_ac": "A0A8V0X4G3", "gene_name": "POLA1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0X4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0X4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G3" } ] } ] }, { "uniprot_ac": "A0A8V0XWC6", "gene_name": "TERT", "activity": [ { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0XWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWC6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V0XWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWC6" } ] } ] }, { "uniprot_ac": "A0A8V0XWS0", "gene_name": "PRIMPOL", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0XWS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWS0" } ] }, { "ec_number": "2.7.7.102", "activity": "ssDNA + n dNTP = ssDNA/pppdN(pdN)n-1 hybrid + (n-1) diphosphate.", "evidence": [ { "id": "A0A8V0XWS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWS0" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0XWS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWS0" } ] }, { "ec_number": "2.7.7.102", "activity": "", "evidence": [ { "id": "A0A8V0XWS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWS0" } ] } ] }, { "uniprot_ac": "A0A8V0Y2U3", "gene_name": "POLK", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0Y2U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0Y2U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U3" } ] } ] }, { "uniprot_ac": "A0A8V0YNB2", "gene_name": "REV3L", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0YNB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8P6", "gene_name": "POLL", "activity": [ { 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2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0ZBR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR9" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0ZBR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR9" } ] } ] }, { "uniprot_ac": "A0A8V0ZUF2", "gene_name": "POLE", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0ZUF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF2" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0ZUF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF2" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNC2-1", "uniprot_ac": "A0A8V0YNC2", "uniprot_id": "A0A8V0YNC2_CHICK", "mass": { "chemical_mass": 161964.0, "monoisotopic_mass": 161964.0 }, "refseq": { "ac": "NP_001376445", "name": "copper-transporting ATPase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445" }, "gene_names": [ { "name": "ATP7A", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ] }, { "name": "ATP7A", "type": "synonym", "evidence": [ { "id": "NP_001376445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445" } ] } ], "protein_names": [ { "name": "Copper-transporting ATPase 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2/entry#names_and_taxonomy" } ] }, { "name": "7.2.2.8", "type": "synonym", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2/entry#names_and_taxonomy" } ] }, { "name": "ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)", "type": "synonym", "evidence": [ { "id": "NP_001376445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445" } ] }, { "name": "Copper pump 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2/entry#names_and_taxonomy" } ] }, { "name": "copper-transporting ATPase 1", "type": "synonym", "evidence": [ { "id": "NP_001376445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.21027.1, SRR13267659.294971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_001376445.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP7A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2", "locus": { "chromosome": "4", "start_pos": 12891705, "end_pos": 12864306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013678", "url": "https://www.ensembl.org/id/ENSGALG00010013678" } ] } } ], "crossref": [ { "id": "cd00371", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00371", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02094", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02094", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747741", "url": "https://www.ncbi.nlm.nih.gov/gene/101747741", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NAMTEHE", "url": "https://omabrowser.org/oma/group/NAMTEHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNC2", "url": "https://www.orthodb.org/?gene=A0A8V0YNC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46594:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46594:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6803544", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803544", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25792", "url": "https://www.rhea-db.org/rhea/25792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEARSIVIGVEGMTCHSCVQTIEQHVGKMNGIHNVKVSLEDKNAVIIYDSKLHTPGTLQEAIYDMGFDATSAGSNPQPVLPDTIFLTIPTQSALTSKELRSTLLKNKGILDVKVSSDQKSAVVTFLSSIINGKQIVQMVPGVDLSISAPEVTAGTCEDPSWSQTSSVLLRLKVEGMTCHSCTSTIEGRIGKLQGIQRIKVSLDNQEAAVVYQPHLITAEEIKCQIEAAGFTASFKKQPRPLKLNAVDLERLKNTQTKSSDTAPLKENTRNVNDTKTVVFKIDGMHCSSCVLNIQSTISTLPSVTSIVVSLENKSAIVKYNPNLITVDVLRSAIEAVSPQTFKVSLLDKYENVALFPALASPLKSVKDAGQPLTQVVVINIEGMTCSSCVQSIEGVISQKAGVRSINVSLANHNGTIEYDPLQTCPEDLRSSIENMGFDASLPEKTELPVGITQPTSKEQLESAEPTSKMLRSSVAEQESKSLSKCYIQVTGMTCASCVANIERNLRREDGIHSVLVALMAGKAEVRYNPAVIHPSAIAELIRELGFGATVMENSGEGDGILDLVVRGMTSAACVHKIESTLMKTNGVLYCSVALATNKAHIKYDPEIIGPRDIIQVIKDLDFTTALVKKDRSASHLDHRQEIRQWRRSFFVSLVFCIPVMAMMIYMMVVDSQLSDAHQHLNMSNEEMEAIHSSMFLEHQLLPGLSVMNFLSFLLCVPVQIFGGWHFYIQAYKALKHRTANMDVLIVLATSVAFVYSFVILLVAMAEKAKVNPVTFFDTPPMLLAFISLGRWLEHVAKGKTSEALARLISLQATEATIVTLGPDNILLSEEQVDVELVQRGDIVKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVTKKPGNTVIAGSINQNGLLLISATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKISGYFVPFIVVVSVITLFAWIIIGFVDFEIVEKYFLGYNKSISAAEVIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVNVVVFDKTGTITHGTPEVMRVKYLVENNRLPHNKMLAIVGTAESNSEHPLGAAITKYCKKELGSEILGTCTDFQVVPGCGISCKVTNIEPLLYRKNKMVEENNIKNVTLVKVEEHMEESVQPALIIDADLPTAVTSQKYSVLIGNREWMNRNGLLVKNDVDKAMIEHERRGRTAVLVAVDGVLCGLIAIADTVKPEAELAVYTLKNMGLEVVLMTGDNSKTARSIASQVGISKVFAEVLPSHKVAKVKQLQDEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIKDDLMDVVASIDLSRKTVKRIRINFVFALIYNLVGVPIAAGVFLPVGLVLQPWMGSAAMAASSVSVVLSSLLLKMYQKPSSEKLEFRARGQMKQKSPSEISVHIGIDETGTGTRKLSLMDRIINYSRASINSLFSDKRSVNSIVLNEPDKHSLLVGDFGEDDDTTL", "length": 1494, "header": "tr|A0A8V0YNC2-1|A0A8V0YNC2_CHICK Isoform 1 of Copper-transporting ATPase 1 OS=Gallus gallus OX=9031 GN=ATP7A PE=1 SV=1 CANONICAL=A0A8V0YNC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2/entry", "sequence": { "sequence": "MEARSIVIGVEGMTCHSCVQTIEQHVGKMNGIHNVKVSLEDKNAVIIYDSKLHTPGTLQEAIYDMGFDATSAGSNPQPVLPDTIFLTIPTQSALTSKELRSTLLKNKGILDVKVSSDQKSAVVTFLSSIINGKQIVQMVPGVDLSISAPEVTAGTCEDPSWSQTSSVLLRLKVEGMTCHSCTSTIEGRIGKLQGIQRIKVSLDNQEAAVVYQPHLITAEEIKCQIEAAGFTASFKKQPRPLKLNAVDLERLKNTQTKSSDTAPLKENTRNVNDTKTVVFKIDGMHCSSCVLNIQSTISTLPSVTSIVVSLENKSAIVKYNPNLITVDVLRSAIEAVSPQTFKVSLLDKYENVALFPALASPLKSVKDAGQPLTQVVVINIEGMTCSSCVQSIEGVISQKAGVRSINVSLANHNGTIEYDPLQTCPEDLRSSIENMGFDASLPEKTELPVGITQPTSKEQLESAEPTSKMLRSSVAEQESKSLSKCYIQVTGMTCASCVANIERNLRREDGIHSVLVALMAGKAEVRYNPAVIHPSAIAELIRELGFGATVMENSGEGDGILDLVVRGMTSAACVHKIESTLMKTNGVLYCSVALATNKAHIKYDPEIIGPRDIIQVIKDLDFTTALVKKDRSASHLDHRQEIRQWRRSFFVSLVFCIPVMAMMIYMMVVDSQLSDAHQHLNMSNEEMEAIHSSMFLEHQLLPGLSVMNFLSFLLCVPVQIFGGWHFYIQAYKALKHRTANMDVLIVLATSVAFVYSFVILLVAMAEKAKVNPVTFFDTPPMLLAFISLGRWLEHVAKGKTSEALARLISLQATEATIVTLGPDNILLSEEQVDVELVQRGDIVKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVTKKPGNTVIAGSINQNGLLLISATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKISGYFVPFIVVVSVITLFAWIIIGFVDFEIVEKYFLGYNKSISAAEVIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVNVVVFDKTGTITHGTPEVMRVKYLVENNRLPHNKMLAIVGTAESNSEHPLGAAITKYCKKELGSEILGTCTDFQVVPGCGISCKVTNIEPLLYRKNKMVEENNIKNVTLVKVEEHMEESVQPALIIDADLPTAVTSQKYSVLIGNREWMNRNGLLVKNDVDKAMIEHERRGRTAVLVAVDGVLCGLIAIADTVKPEAELAVYTLKNMGLEVVLMTGDNSKTARSIASQVGISKVFAEVLPSHKVAKVKQLQDEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIKDDLMDVVASIDLSRKTVKRIRINFVFALIYNLVGVPIAAGVFLPVGLVLQPWMGSAAMAASSVSVVLSSLLLKMYQKPSSEKLEFRARGQMKQKSPSEISVHIGIDETGTGTRKLSLMDRIINYSRASINSLFSDKRSVNSIVLNEPDKHSLLVGDFGEDDDTTL", "length": 1494, "header": "tr|A0A8V0YNC2-1|A0A8V0YNC2_CHICK Isoform 1 of Copper-transporting ATPase 1 OS=Gallus gallus OX=9031 GN=ATP7A PE=1 SV=1 CANONICAL=A0A8V0YNC2-1" }, "locus": { "chromosome": "4", "start_pos": 12888575, "end_pos": 12870594, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032877.1", "url": "https://www.ensembl.org/id/ENSGALT00010032877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019462.1", "url": "https://www.ensembl.org/id/ENSGALP00010019462.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6803544", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803544", "resource": "Reactome", "description": "Ion influx/efflux at host-pathogen interface" }, { "id": "R-GGA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1ML70-1", "protein_name": "Copper-transporting ATPase 1", "gene_name": "ATP7A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVNGASMKIEECKEEIKMDLSVSVNSVTISVEGMTCSSCVWTIEQQIGKLNGVHHIKVSLEEKNATVIYDPKLQTPKTLQEAIDDMGFDAILHNPKPLPVLTETVFLTVTASLVPPWDHIQSTLLKTKGVTDIKISPQQRTAVVTIIPSIVNANQIVELVPDLSLDTGTLEKKSGTCEDYSMAQPGEVMLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATVVYQPHLITAEEIKKQIEVVGFTAFIKKQPKYLKLGAIDIERLKNTPVKSSEGSQQKSPSYTSNSTVIFTIDGMHCKSCVSNIESALSTLQHISSVVVSLENKSAIVKYNASLVTPETLRKAIEAISQGQYRVSSASEIESTSNSPSSSSLQKSPLNIVSQPLTQETVINIDGMTCNSCVQSIEGVISKKAGVKSIQVSLANGKGTVEYDPLLTSPETLREAIENMGFDASLSDTNEPLVVIAQPSSEMPLLTSTNEFHTKMMTPIHDKEEPKTSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPALIQPPVIAELIRELGFGSTVIENADEGDGVLELVVRGMTCASCVHKIESTLTKHRGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRAFLVSLFFCIPVMGLMIYMMVMDHHLASLQHNQNMSQEEMINIHSSMFLERQILPGLSIMNLLSFLLCVPVQFFGGWHFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPVTFFDTPPMLFVFIALGRWLEHVAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKSGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVIVSIATLLVWIIIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNRISRNKILAIVGTAESNSEHPLGAAITKYCKQELDTETLGTCIDFQVVPGCGINCKVTNIEALLHKNNWKIEENNIKNASLVQIDESNEQSSTSSSMIIDAQFSNALNAQQYKVLIGNREWMIRNGLAINNSVNDSMTEHERRGRTAVLVAVDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYENYELHARNQMGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVGTSEPDKHSLLVGDCREDDDSAL", "length": 1517 }, "evidence": [ { "id": "A0A8V0YNC2", "url": "https://omabrowser.org/oma/group/A0A8V0YNC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P70705-1", "protein_name": "Copper-transporting ATPase 1", "gene_name": "Atp7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPNMDANSITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATVIYNPKLQTPKTLQEAIDDMGFDALLHNANPLPVLTNTVFLTVTAPLALPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSANQIVELVPDLSLDMGTQEKKSGTSEEHSTPQAGEVLLKMRVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKSTPVKSSEGSQQKSPAYPSDSAITFTIDGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEILRKAIEAVSPGQYRVSISSEVESPTSSPSSSSLQKMPLNLVSQPLTQEVVININGMTCNSCVQSIEGVISKKPGVKSIHVSLTNSTGTIEYDPLLTSPEPLREAIEDMGFDAVLPADMKEPLVVIAQPSLETPLLPSTTEPENVMTPVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAELIRELGFGAVVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGNLGFEASLVKKDRSANHLDHKREIKQWRGSFLVSLFFCIPVMGLMIYMMVMDHHLATLNHNQNMSNEEMINMHSSMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALRHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVEAYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNKISRNKILAIVGTAESNSEHPLGAAVTKYCKQELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLVQIDAINEQSSPSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMASVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFLPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYDNYELRPRSHTGQRSPSEISVHVGIDDTSRNSPRLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTTL", "length": 1492 }, "evidence": [ { "id": "A0A8V0YNC2", "url": "https://omabrowser.org/oma/group/A0A8V0YNC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64430-1", "protein_name": "Copper-transporting ATPase 1", "gene_name": "Atp7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1491 }, "evidence": [ { "id": "A0A8V0YNC2", "url": "https://omabrowser.org/oma/group/A0A8V0YNC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "superoxide dismutase copper chaperone activity", "id": "GO:0016532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016532", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "copper-dependent protein binding", "id": "GO:0032767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032767", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "cuprous ion binding", "id": "GO:1903136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "P-type divalent copper transporter activity", "id": "GO:0043682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "P-type monovalent copper transporter activity", "id": "GO:0140581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "response to copper ion", "id": "GO:0046688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "copper ion export", "id": "GO:0060003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" }, { "name": "positive regulation of melanin biosynthetic process", "id": "GO:0048023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1298, "end_pos": 1300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1452, "end_pos": 1454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25792", "name": "", "equation": "Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNC2-1", "A0A8V0X9Y2-1" ], "evidence": [ { "id": "25792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25792" } ] }, { "id": "R-GGA-6803545", "name": "ATP7A transports cytosolic Cu2+ to phagosomal lumen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, phagocytic vesicle membrane, phagocytic vesicle lumen", "input_participant_list": [], "output_participant_list": [ "R-ALL-6803540", "R-GGA-3697884" ], "enzyme_list": [ "A0A8V0YNC2-1" ], "evidence": [ { "id": "R-GGA-6803545", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803545" } ] }, { "id": "R-GGA-936802", "name": "ATP7A transports cytosolic Cu1+ to extracellular region", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-ALL-3299744" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNC2-1" ], "evidence": [ { "id": "R-GGA-936802", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-936802" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-3299744", "participant_name": "Cu1+ [cytosol]", "crossref": [ { "id": "49552", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6803540", "participant_name": "Cu1+ [phagocytic vesicle lumen]", "crossref": [ { "id": "C00070", "database": "COMPOUND", "url": "" }, { "id": "49552", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-GGA-3697884", "participant_name": "ATOX1 [cytosol]", "crossref": [ { "id": "ENSGALG00010014319", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010034492", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010020267", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YNQ4", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X9Y2", "gene_name": "ATP7B", "activity": [ { "ec_number": "7.2.2.8", "activity": "Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y2" } ] }, { "ec_number": "7.2.2.8", "activity": "", "evidence": [ { "id": "A0A8V0X9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y2" } ] } ] }, { "uniprot_ac": "A0A8V0YNC2", "gene_name": "ATP7A", "activity": [ { "ec_number": "7.2.2.8", "activity": "Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ] }, { "ec_number": "7.2.2.8", "activity": "", "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC2" }, { "id": "PS50846", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMA", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 70, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.2.2.8", "ec_name": "Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "7.2.2.8", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.8" }, { "id": "7.2.2.8", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.2.2.8" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": 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0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNE3-1", "uniprot_ac": "A0A8V0YNE3", "uniprot_id": "A0A8V0YNE3_CHICK", "mass": { "chemical_mass": 49924.0, "monoisotopic_mass": 49924.0 }, "refseq": {}, "gene_names": [ { "name": "FNTA", "type": "recommended", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] } ], "protein_names": [ { "name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.58", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.59", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "CAAX farnesyltransferase subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "FTase-alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "Ras proteins prenyltransferase subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] }, { "name": "Type I protein geranyl-geranyltransferase subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3#function" }, { "database": "UniProtKB", "id": "ARBA00055408", "url": "https://www.uniprot.org/uniprotkb/ARBA00055408#function" }, { "database": "UniProtKB", "id": "A0A8V0YTE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTE3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FNTA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3", "locus": { "chromosome": "Z", "start_pos": 54530083, "end_pos": 54543938, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013732", "url": "https://www.ensembl.org/id/ENSGALG00010013732" } ] } } ], "crossref": [ { "id": "A0A8V0YNE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "427299", "url": "https://www.ncbi.nlm.nih.gov/gene/427299", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WAIRTFN", "url": "https://omabrowser.org/oma/group/WAIRTFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNE3", "url": "https://www.orthodb.org/?gene=A0A8V0YNE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTE3", "url": "https://www.orthodb.org/?gene=A0A8V0YTE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01239", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01239", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-111465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648002", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9953170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13345", "url": "https://www.rhea-db.org/rhea/13345", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "21240", "url": "https://www.rhea-db.org/rhea/21240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEGMAPAELQAEGGTAVEPESGFGQLLEEEEEDGGYVLYRYGRVSAASERLGHVFPGTDVRRRGGGGGMLRRRTRTRKEGSGHRCVCFTVRVALYKHWKFENIFVCAYRDRKEWADIEPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQKDERSERAFKLTADAIELNAANYTVWHFRRVLLQSLGKDLYEELKYITAIIEDQPKNYQVWHHRRVLVEWLQDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDDELEYVDQLLREDVRNNSVWNQRYFVIFNTTGYDDPAVLDREVQYTLEMITAVPHNESAWNYLKGILQDRGLSKYPNLLEQLLSLQPSHSSPYLIAFLVDIYEDMLENQCENKEETLNKALELCEILAKEKDTIRKEYWRYIGRSLKNKHSSNTEQSTVTDKQQ", "length": 425, "header": "tr|A0A8V0YNE3-1|A0A8V0YNE3_CHICK Isoform 1 of Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Gallus gallus OX=9031 GN=FNTA PE=1 SV=1 CANONICAL=A0A8V0YNE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3/entry", "sequence": { "sequence": "MASEGMAPAELQAEGGTAVEPESGFGQLLEEEEEDGGYVLYRYGRVSAASERLGHVFPGTDVRRRGGGGGMLRRRTRTRKEGSGHRCVCFTVRVALYKHWKFENIFVCAYRDRKEWADIEPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQKDERSERAFKLTADAIELNAANYTVWHFRRVLLQSLGKDLYEELKYITAIIEDQPKNYQVWHHRRVLVEWLQDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDDELEYVDQLLREDVRNNSVWNQRYFVIFNTTGYDDPAVLDREVQYTLEMITAVPHNESAWNYLKGILQDRGLSKYPNLLEQLLSLQPSHSSPYLIAFLVDIYEDMLENQCENKEETLNKALELCEILAKEKDTIRKEYWRYIGRSLKNKHSSNTEQSTVTDKQQ", "length": 425, "header": "tr|A0A8V0YNE3-1|A0A8V0YNE3_CHICK Isoform 1 of Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Gallus gallus OX=9031 GN=FNTA PE=1 SV=1 CANONICAL=A0A8V0YNE3-1" }, "locus": { "chromosome": "Z", "start_pos": 54540931, "end_pos": 54531589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032947.1", "url": "https://www.ensembl.org/id/ENSGALT00010032947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019487.1", "url": "https://www.ensembl.org/id/ENSGALP00010019487.1" } ] } }, { "isoform_ac": "A0A8V0YTE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTE3/entry", "sequence": { "sequence": "MQYPSYPSIGDPTTPASPGGALQLRCRSALCSRPTSARPRKRRLDGAMASEGMAPAELQAEGGTAVEPESGFGQLLEEEEEDGGYVLYRDRKEWADIEPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQKDERSERAFKLTADAIELNAANYTVWHFRRVLLQSLGKDLYEELKYITAIIEDQPKNYQVWHHRRVLVEWLQDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDDELEYVDQLLREDVRNNSVWNQRYFVIFNTTGYDDPAVLDREVQYTLEMITAVPHNESAWNYLKGILQDRGLSKYPNLLEQLLSLQPSHSSPYLIAFLVDIYEDMLENQCENKEETLNKALELCEILAKEKDTIRKEYWRYIGRSLKNKHSSNTEQSTVTDKQQ", "length": 403, "header": "tr|A0A8V0YTE3-1|A0A8V0YNE3_CHICK Computationally mapped isoform of Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Gallus gallus OX=9031 GN=FNTA PE=1 SV=1 CANONICAL=A0A8V0YNE3-1" }, "locus": { "chromosome": "Z", "start_pos": 54543739, "end_pos": 54531589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032952.1", "url": "https://www.ensembl.org/id/ENSGALT00010032952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019490.1", "url": "https://www.ensembl.org/id/ENSGALP00010019490.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-111465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111465", "resource": "Reactome", "description": "Apoptotic cleavage of cellular proteins" }, { "id": "R-GGA-9648002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "resource": "Reactome", "description": "RAS processing" }, { "id": "R-GGA-9953170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "resource": "Reactome", "description": "GBP-mediated host defense" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S4G1-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "FNTA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAADGVGEAAQGGDPGQPEPPPPPQPHPPPPPPQPPQEEAAAASPMDDGFLSLDSPTYVLYRDRPEWADIDPVPQNDGPNPVVQIIYSEKFQDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVCHQLYKLGQPQAVKSPPYWLRRILSRNGHFRRVLLKSLQKDLHEEMNYISAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILTQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAILEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTESDPPTNVQQ", "length": 402 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P29703-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "RAM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISLNELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTLNNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDFQHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNISPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLAYHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN", "length": 316 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P49354-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "FNTA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ", "length": 379 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q04631-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "Fnta", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATEGVGESAPGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYIIAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSRESDIPASV", "length": 377 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54RT9-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "fntA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSSEEDDGYVPFSKRPEWSDVKPLAQDDGPHPICPILYSEVFKDKMNYFRAILKSKEKSLRVLDLLEEVIQENPSNYTIWYYRREVLKAIEQDETIEYDIQQEMNLLNDMGETDPKNYQIWNHRRFIVEKYIGSDNKEKEFLSGVLLEDAKNYHAWSHRQWLLKTYRDWNGELAMVDKLLSLDHRNNSVWNHRFFVISNLNPSPFPLSLIEREVEFAFNHIRHSPNNESPWSYLKGLFKGQKISTIYPSLLDILLEMKSKYIGCSHVNSIILDIYQEQNTKISLENSLNICKLLSETIDPIHKNYWNFKYNTISDQLKLIN", "length": 322 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q61239-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "Fnta", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV", "length": 377 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LX33-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "FTA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNFDETVPLSQRLEWSDVVPLTQDDGPNPVVPIAYKEEFRETMDYFRAIYFSDERSPRALRLTEETLLLNSGNYTVWHFRRLVLEALNHDLFEELEFIERIAEDNSKNYQLWHHRRWVAEKLGPDVAGRELEFTRRVLSLDAKHYHAWSHRQWTLRALGGWEDELDYCHELLEADVFNNSAWNQRYYVITQSPLLGGLEAMRESEVSYTIKAILTNPANESSWRYLKALYKDDKESWISDPSVSSVCLNVLSRTDCFHGFALSTLLDLLCDGLRPTNEHKDSVRALANEEPETNLANLVCTILGRVDPVRANYWAWRKSKITVAAI", "length": 326 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VR31-1", "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "Fnta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDSSDEEYLGTDWLAYSERSDWEDVQPLAQDDGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRALDLTTDALRLNPANYTVWQYRRDVLRELKADLYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLNDPSNELELTENALVNDGDAKNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVIKHFGFTPELIQRELSYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVDFVEELYQAGNRSPYLLAFLIDLYQEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVANHLKNQLSTVEQK", "length": 331 }, "evidence": [ { "id": "A0A8V0YNE3", "url": "https://omabrowser.org/oma/group/A0A8V0YNE3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein farnesyltransferase activity", "id": "GO:0004660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004660", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "CAAX-protein geranylgeranyltransferase activity", "id": "GO:0004662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004662", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "CAAX-protein geranylgeranyltransferase complex", "id": "GO:0005953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "protein farnesyltransferase complex", "id": "GO:0005965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of microtubule-based movement", "id": "GO:0060632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" }, { "name": "peptide pheromone maturation", "id": "GO:0007323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13345", "name": "", "equation": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RSD4-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "13345", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13345" } ] }, { "id": "21240", "name": "", "equation": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4E5-1", "A0A8V0YNE3-1", "F1NE58-1" ], "evidence": [ { "id": "21240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21240" } ] }, { "id": "R-GGA-201640", "name": "Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-2530516" ], "output_participant_list": [ "R-GGA-202869", "R-GGA-202872" ], "enzyme_list": [ "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-201640", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201640" } ] }, { "id": "R-GGA-9647978", "name": "pro-RAS proteins are farnesylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-2530486" ], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A1L1RSD4-1", "P08642-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-9647978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9647978" } ] }, { "id": "R-GGA-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RSD4-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-9647987", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9647987" } ] }, { "id": "R-GGA-9947999", "name": "FNTA:PGGT1B geranylgeranylates GBP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9947981" ], "output_participant_list": [], "enzyme_list": [ "F1NE58-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-9947999", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9947999" } ] }, { "id": "R-GGA-9948016", "name": "FNTA:FNTB transfers farnesyl to GBP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RSD4-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-9948016", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9948016" } ] }, { "id": "R-GGA-9954195", "name": "FNTA:PGGT1B geranylgeranylates GBP5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NE58-1", "A0A8V0YNE3-1" ], "evidence": [ { "id": "R-GGA-9954195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954195" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2530486", "participant_name": "FPP [cytosol]", "crossref": [ { "id": "50277", "database": "ChEBI", "url": "" }, { "id": "ZINC000012494625", "database": "ZINC", "url": "" }, { "id": "ZINC000013507240", "database": "ZINC", "url": "" }, { "id": "ZINC000013507238", "database": "ZINC", "url": "" }, { "id": "ZINC000013507236", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9947981", "participant_name": "GGPP [cytosol]", "crossref": [ { "id": "57533", "database": "ChEBI", "url": "" }, { "id": "ZINC000012495043", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-GGA-202869", "participant_name": "FNTA [cytosol]", "crossref": [ { "id": "ENSGALP00010019487", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0YNE3", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010013732", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032947", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-202872", "participant_name": "FNTA [cytosol]", "crossref": [ { "id": "A0A8V0YNE3", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010019487", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032947", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010013732", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-2530516", "participant_name": "FNTA [cytosol]", "crossref": [ { "id": "A0A8V0YNE3", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010013732", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010019487", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010032947", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1L1RSD4", "gene_name": "FNTB", "activity": [ { "ec_number": "2.5.1.58", "activity": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0A1L1RSD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD4" } ] }, { "ec_number": "2.5.1.58", "activity": "", "evidence": [ { "id": "A0A1L1RSD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD4" } ] } ] }, { "uniprot_ac": "A0A8V0YNE3", "gene_name": "FNTA", "activity": [ { "ec_number": "2.5.1.58", "activity": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.58", "activity": "", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] } ] }, { "uniprot_ac": "F1NE58", "gene_name": "PGGT1B", "activity": [ { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "F1NE58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE58" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "F1NE58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE58" } ] } ] }, { "uniprot_ac": "F1P4E5", "gene_name": "RABGGTB", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "Q5F352", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.58", "ec_name": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "2.5.1.58", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.58" }, { "id": "2.5.1.58", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.58" } ] }, { "ec_number": "2.5.1.59", "ec_name": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "2.5.1.59", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.59" }, { "id": "2.5.1.59", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.59" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNF9-1", "uniprot_ac": "A0A8V0YNF9", "uniprot_id": "A0A8V0YNF9_CHICK", "mass": { "chemical_mass": 88310.0, "monoisotopic_mass": 88310.0 }, "refseq": { "ac": "XP_024998023", "name": "probable ATP-dependent RNA helicase DDX27 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998023" }, "gene_names": [ { "name": "DDX27", "type": "recommended", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "name": "DDX27", "type": "synonym", "evidence": [ { "id": "XP_024998023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998023" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX27", "type": "recommended", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 27", "type": "synonym", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DDX27 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024998023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024998023.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998023" } ] }, { "annotation": "Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA.", "evidence": [ { "database": "UniProtKB", "id": "F1NQV5", "url": "https://www.uniprot.org/uniprotkb/F1NQV5#function" }, { "database": "UniProtKB", "id": "ARBA00053341", "url": "https://www.uniprot.org/uniprotkb/ARBA00053341#function" }, { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9#function" }, { "database": "UniProtKB", "id": "A0A8V0YWV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWV9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDX27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9", "locus": { "chromosome": "20", "start_pos": 11095903, "end_pos": 11102420, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016235", "url": "https://www.ensembl.org/id/ENSGALG00010016235" } ] } } ], "crossref": [ { "id": "A0A8V0YNF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006974", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006974", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419308", "url": "https://www.ncbi.nlm.nih.gov/gene/419308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419308", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIDPPKQ", "url": "https://omabrowser.org/oma/group/MIDPPKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF9", "url": "https://www.orthodb.org/?gene=A0A8V0YNF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWV9", "url": "https://www.orthodb.org/?gene=A0A8V0YWV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQV5", "url": "https://www.orthodb.org/?gene=F1NQV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024998023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQV5", "url": "https://www.uniprot.org/uniprotkb/F1NQV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQV5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHGLGLVGTIAEGDEGPEEPESGDSEDEEVGPARFGSDDVRPARFGSAGSRVSLQEVRPAPGPGRRGAAGGDFSAAFVFGEVEAGGEGAWAAALRQLRGKKSATTLDEKIEKVRQKRKFQEKEAKQAKVKDGNAETEDNQSEKRECEDFGREEEEDNESQYSLDDETIFTKADTLKVKERKRSKKGGQKEAESFFEDASEYDDNLSFQDMNLSRPLLKAITALGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFILPVLERLIYKPRQAPITRVLVLVPTRELGIQVHSVTKQLAQFSSVTTCLAVGGLDVKTQEAALRSGPDILIATPGRLIDHLHNCPSFHLSSVEVLILDEADRMLDEYFEEQMKEIIRLCSRHRQTMLFSATMTEEVKDLASVSLKNPTRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVSALLTRTFPDHVMLFTQTKKQAHRMHILLGLMGLRVGELHGNLSQAQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTTKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKTPVKARILPQDVILKFREKIENLEKDVYAVLCLEREEREMQQSEAQINKAKKQLEEGKQEAATKGVERSWFQTREERKKEKLAKALQEFDLALRGKKKRKKFMQDTQRKAQMTPEERSQFEILKSQMYAERLAKRNRRVKRARALPEEEPAAAPKGPKRKKKVSVFDEELTNTSRKALKQYRAGPSFEDRKRLGMAQRRKGGNFKSKSRYKRK", "length": 784, "header": "tr|A0A8V0YNF9-1|A0A8V0YNF9_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX27 OS=Gallus gallus OX=9031 GN=DDX27 PE=1 SV=1 CANONICAL=A0A8V0YNF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9/entry", "sequence": { "sequence": "MLHGLGLVGTIAEGDEGPEEPESGDSEDEEVGPARFGSDDVRPARFGSAGSRVSLQEVRPAPGPGRRGAAGGDFSAAFVFGEVEAGGEGAWAAALRQLRGKKSATTLDEKIEKVRQKRKFQEKEAKQAKVKDGNAETEDNQSEKRECEDFGREEEEDNESQYSLDDETIFTKADTLKVKERKRSKKGGQKEAESFFEDASEYDDNLSFQDMNLSRPLLKAITALGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFILPVLERLIYKPRQAPITRVLVLVPTRELGIQVHSVTKQLAQFSSVTTCLAVGGLDVKTQEAALRSGPDILIATPGRLIDHLHNCPSFHLSSVEVLILDEADRMLDEYFEEQMKEIIRLCSRHRQTMLFSATMTEEVKDLASVSLKNPTRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVSALLTRTFPDHVMLFTQTKKQAHRMHILLGLMGLRVGELHGNLSQAQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTTKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKTPVKARILPQDVILKFREKIENLEKDVYAVLCLEREEREMQQSEAQINKAKKQLEEGKQEAATKGVERSWFQTREERKKEKLAKALQEFDLALRGKKKRKKFMQDTQRKAQMTPEERSQFEILKSQMYAERLAKRNRRVKRARALPEEEPAAAPKGPKRKKKVSVFDEELTNTSRKALKQYRAGPSFEDRKRLGMAQRRKGGNFKSKSRYKRK", "length": 784, "header": "tr|A0A8V0YNF9-1|A0A8V0YNF9_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX27 OS=Gallus gallus OX=9031 GN=DDX27 PE=1 SV=1 CANONICAL=A0A8V0YNF9-1" }, "locus": { "chromosome": "20", "start_pos": 11102221, "end_pos": 11096523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039030.1", "url": "https://www.ensembl.org/id/ENSGALT00010039030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022541.1", "url": "https://www.ensembl.org/id/ENSGALP00010022541.1" } ] } }, { "isoform_ac": "A0A8V0YWV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWV9/entry", "sequence": { "sequence": "MLHGLGLVGTIAEGDEGPEEPESGDSEDEEEVRPAPGPGRRGAAGGDFSAAFVFGEVEAGGEGAWAAALRQLRGKEKEAKQAKVKDGNAETEDNQSEKRECEDFGREEEEDNESQYSLDDETIFTKADTLKVKERKRSKKGGQKEAESFFEDASEYDDNLSFQDMNLSRPLLKAITALGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFILPVLERLIYKPRQAPITRVLVLVPTRELGIQVHSVTKQLAQFSSVTTCLAVGGLDVKTQEAALRSGPDILIATPGRLIDHLHNCPSFHLSSVEVLILDEADRMLDEYFEEQMKEIIRLCSRHRQTMLFSATMTEEVKDLASVSLKNPTRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVSALLTRTFPDHVMLFTQTKKQAHRMHILLGLMGLRVGELHGNLSQAQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTTKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKTPVKARILPQDVILKFREKIENLEKDVYAVLCLEREEREMQQSEAQINKAKKQLEEGKQEAATKGVERSWFQTREERKKEKLAKALQEFDLALRGKKKRKKFMQDTQRKAQMTPEERSQFEILKSQMYAERLAKRNRRVKRARALPEEEPAAAPKGPKRKKKVSVFDEELTNTSRKALKQYRAGPSFEDRKRLGMAQRRKGGNFKSKSRYKRK", "length": 738, "header": "tr|A0A8V0YWV9-1|A0A8V0YNF9_CHICK Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX27 OS=Gallus gallus OX=9031 GN=DDX27 PE=1 SV=1 CANONICAL=A0A8V0YNF9-1" }, "locus": { "chromosome": "20", "start_pos": 11102221, "end_pos": 11096523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039012.1", "url": "https://www.ensembl.org/id/ENSGALT00010039012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022533.1", "url": "https://www.ensembl.org/id/ENSGALP00010022533.1" } ] } }, { "isoform_ac": "F1NQV5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQV5/entry", "sequence": { "sequence": "MLHGLGLVGTIAEGDEGPEEPESGDSEDEEEVRPAPGPGRRGAAGGDFSAAFVFGEVEAGGEGAWAAALRQLRGKKSATTLDEKIEKVRQKRKFQEKEAKQAKVKDGNAETEDNQSEKRECEDFGREEEEDNESQYSLDDETIFTKADTLKVKERKRSKKGGQKEAESFFEDASEYDDNLSFQDMNLSRPLLKAITALGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFILPVLERLIYKPRQAPITRVLVLVPTRELGIQVHSVTKQLAQFSSVTTCLAVGGLDVKTQEAALRSGPDILIATPGRLIDHLHNCPSFHLSSVEVLILDEADRMLDEYFEEQMKEIIRLCSRHRQTMLFSATMTEEVKDLASVSLKNPTRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVSALLTRTFPDHVMLFTQTKKQAHRMHILLGLMGLRVGELHGNLSQAQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTTKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKTPVKARILPQDVILKFREKIENLEKDVYAVLCLEREEREMQQSEAQINKAKKQLEEGKQEAATKGVERSWFQTREERKKEKLAKALQEFDLALRGKKKRKKFMQDTQRKAQMTPEERSQFEILKSQMYAERLAKRNRRVKRARALPEEEPAAAPKGPKRKKKVSVFDEELTNTSRKALKQYRAGPSFEDRKRLGMAQRRKGGNFKSKSRYKRK", "length": 758, "header": "tr|F1NQV5-1|A0A8V0YNF9_CHICK Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX27 OS=Gallus gallus OX=9031 GN=DDX27 PE=1 SV=1 CANONICAL=A0A8V0YNF9-1" }, "locus": { "chromosome": "20", "start_pos": 11102221, "end_pos": 11096523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039021.1", "url": "https://www.ensembl.org/id/ENSGALT00010039021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022536.1", "url": "https://www.ensembl.org/id/ENSGALP00010022536.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419308", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1A4H6-1", "protein_name": "Probable ATP-dependent RNA helicase DDX27", "gene_name": "DDX27", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSELGFIRTIGEDEDVQVEPETDSEDEEEEGPIVLGRKQKALQKNRSADFNPDFVFTEKEGMYDGSWAMADVLSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKSEKEKEAKEGSEPEEEEDLERKDVEASEDEESETDYSSADENILTKADTLKIKERKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTKQLAQFCSITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLMRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQKSEAQINTAQRLLEKGKEAPNPEPERSWFQTKEERKKEKIAKALQEFDLALRGKKKRKKFMKEAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRAKRARAMPEEEPVRAPAKKQKQVKKSVFDEELTNTSKKALKQYRAGPSFEERKKLGLPHQRRGGNFKSKSRYKRRK", "length": 765 }, "evidence": [ { "id": "A0A8V0YNF9", "url": "https://omabrowser.org/oma/group/A0A8V0YNF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P32892-1", "protein_name": "ATP-dependent RNA helicase DRS1", "gene_name": "DRS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVVGTKKYSNLDFVPTISDSEDDVPILDSSDDEKVEAKKTTKKRKGKNNKKKVSEGDNLDEDVHEDLDAGFKFDLDADDTTSNFQGWNFLAEGESNKDDAEAFVKKDVDLDKIIRRKGGLVKMAHIDSKQEEETEKEKVEKENDSDDEELAMDGFGMGAPMNNGDENQSEEEEEEEEKEEEEEEEEEQEEMTLEKGGKDDEIDEEDDSEEAKADFYAPETEGDEAKKQMYENFNSLSLSRPVLKGLASLGYVKPSPIQSATIPIALLGKDIIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIARFVSGITFGLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIRNSASFNVDSVEILVMDEADRMLEEGFQDELNEIMGLLPSNRQNLLFSATMNSKIKSLVSLSLKKPVRIMIDPPKKAATKLTQEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRLRIIMGLLGMSVGELHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYDMPKSYEIYLHRVGRTARAGREGRSVTFVGESSQDRSIVRAAIKSVEENKSLTQGKALGRNVDWVQIEETNKLVESMNDTIEDILVEEKEEKEILRAEMQLRKGENMLKHKKEIQARPRRTWFQSESDKKNSKVLGALSRNKKVTNSKKRKREEAKADGNGARSYRKTKTDRIADQERTFKKQKSTNSNKKKGFKSRR", "length": 752 }, "evidence": [ { "id": "A0A8V0YNF9", "url": "https://omabrowser.org/oma/group/A0A8V0YNF9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54TJ4-1", "protein_name": "Probable ATP-dependent RNA helicase ddx27", "gene_name": "ddx27", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLVDNQTSTTTNLVGTKRKSPENDFIMTIDIAGDDDFVDDDENDDDEDLKEDFFFEESDKPQLPWDFAPTIEKMKQQTHKKTDGQTSLEDKINQRKTVKKLKADDDKSVTTKTTNNNKSKKSNNNDNDDDDEEVNEEEEEEEEEEDNENEKEINKKQQQQQQQSNKQTTDKIKVLQSNRKLKKIVEEELPTFEELHLSRPLLKAVQKLGFSQPTPIQAKAIPLALNGKDILASASTGSGKTAAFLLPVLERLLFRDSEYRAIRVLILLPTRELALQCQSVMENLAQFSNITSCLIVGGLSNKAQEVELRKSPDVVIATPGRLIDHLLNAHGIGLDDLEILILDEADRLLDMGFKDEINKIVESCPTNRQTMLFSATLNDEVKTLAKLSLQQPIRVQVDALMQVTSTLEQEFVKIKPQHLSDRPAILLSLCTRVFNQGGTIIFCRSKKEVHRLRIIFGLSDLKAAELHGNLSQEQRFDSLQQFRDGQVNYLLASDVASRGLDIIGVKTVINYNMPNNMANYIHRVGRTARAGMDGKSCSFITDNDRKLLKDIVTKARNKAKSRSVSQDNVNFWRNRIEELTEDIKSIVREEMKEADLRKAEKTLDKAEKIISNADANVETPKVWYKTKQEEDKSKELWKIENNIVNPGKKLKAPIDVTGVNNVPSIKKLKQKKDPYYGLSRKQRRHRQFKEEFEREQQEERKRKGGDDGDDNEEIDSGKMFERSQRAQKSSGKETKRIESLRRNYMAGGALTDQEKQRVDNKKSKKNKRMIVNKKEKKQRLSKK", "length": 783 }, "evidence": [ { "id": "A0A8V0YNF9", "url": "https://omabrowser.org/oma/group/A0A8V0YNF9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q921N6-1", "protein_name": "Probable ATP-dependent RNA helicase DDX27", "gene_name": "Ddx27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAELGFIRTIGENDEVPVEPESDSGDEEEEGPIVLGRKQKALQKNRSADFNPDFVFTEKEGMYDGSWALADVMSQLKKKRAATTLDEKIEKVRKRRKAEDKEAKSGKVEEKEGQADSDLKGQENPGEDEAGSKDEDSETDYSSEDEEILTKADTLKVKEKKKKKKGQAAGGFFEDASEYDKSLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAAVTRVLVLVPTRELGIQVHSVTKQLAQFCSITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLMRTFTDHVMLFTQTKKQAHRMHILLGLLGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTVKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKLEKDVYAVLQLEAEEKEMQQSEAQIDTAQRLLAKGKETADQEPERSWFQTKEERKKEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRTKRARAMPEDEPTGPAKKQKQQQKSVFDEELTNTSKKALKQYRAGPSFEERKQSGLPRQRRGNFKSKSRYKRKK", "length": 760 }, "evidence": [ { "id": "A0A8V0YNF9", "url": "https://omabrowser.org/oma/group/A0A8V0YNF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": 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"uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": 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ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": 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"id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": 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"activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": 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"evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": 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"ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] } ] }, { "uniprot_ac": "O93295", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O93295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93295" } ] } ] }, { 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416045.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANO6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3", "locus": { "chromosome": "1", "start_pos": 30809077, "end_pos": 30739828, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013784", "url": "https://www.ensembl.org/id/ENSGALG00010013784" } ] } } ], "crossref": [ { "id": "A0A8V0YNL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417802", "url": "https://www.ncbi.nlm.nih.gov/gene/417802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417802", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417802", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYAVREQ", "url": "https://omabrowser.org/oma/group/PYAVREQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNL3", "url": "https://www.orthodb.org/?gene=A0A8V0YNL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTM2", "url": "https://www.orthodb.org/?gene=A0A8V0YTM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769743", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAENPDVLLDLEEEEEEGDEEVDEEDGESVLELNQVIIPTYGTVSDQQNLHTPEWADFDNKPDSLFFNDGQRRIDFVLVYEDETKMSHKRSNHKKQKRKRQVYESNLINNGLQLEATRSVLDEKTVFVKVHAPWEVLCTYAEVMHIKLPLQPNDLKTRESAFNWFTRLFRVDENIIKPEQEFFTAPFKREHLSNFYIQDKDTFFNPATRSRIVHFILSRVKYATKQNVKKFGINKLLDTGIYKAAFPLHDSSFGHLSTDPDCPSERYLLYREWAHPKNILKLQPLDFIRKYYGEKIGIYFAWLGFYTNMLIVAAVVGVGCFLYGFFMKDNCTWSQEVCDPNIGGNIIMCPQCDKVCTYWNLTITCESSKKLCIFDSFGTLVFAVFMGIWVTLFLEFWKRRQAELEYEWDTVEYLEQEEQIRPEYEAQCTHVVVNEITQQEEHVPYTACGKCVRITLCTSAVFFWIFLIIASVIGIIVYRLSVFLVFSATLPRHINGTQAIRKYLTPQTATSVTASIISFIVIMVLNIVYEKVAILITDFELPRTQTEYENSLTTKMFLFQFVNYYSSCFYIAFFKGKFVGYPGNPVYWLGKYRNEECDPGGCLLELTTQLAIIVGGKAIWNNIQEVLLPWVKNLIGRYCADARSEKTVPRWEQDYHLQPIGKLGLFYEYLEMVIQFGFVTLFVASFPLAPLLALINNMLEIRLDAWKLTTQFRRMVPQKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGSHSSYTMRGYINNTLSVFSISDFKNASKPFSPWFGNHTTCRYRDFRYPPGHQHQYEHNIYYWHVIAAKLAFIIVMEHVIYFVKFIISYIIPDVSQETKSKVKREKYLTQKILHENDLKVVKKTIGKIADKIIEGVDSTFRPKTE", "length": 912, "header": "tr|A0A8V0YNL3-1|A0A8V0YNL3_CHICK Isoform 1 of Anoctamin OS=Gallus gallus OX=9031 GN=ANO6 PE=1 SV=1 CANONICAL=A0A8V0YNL3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3/entry", "sequence": { "sequence": "MQAENPDVLLDLEEEEEEGDEEVDEEDGESVLELNQVIIPTYGTVSDQQNLHTPEWADFDNKPDSLFFNDGQRRIDFVLVYEDETKMSHKRSNHKKQKRKRQVYESNLINNGLQLEATRSVLDEKTVFVKVHAPWEVLCTYAEVMHIKLPLQPNDLKTRESAFNWFTRLFRVDENIIKPEQEFFTAPFKREHLSNFYIQDKDTFFNPATRSRIVHFILSRVKYATKQNVKKFGINKLLDTGIYKAAFPLHDSSFGHLSTDPDCPSERYLLYREWAHPKNILKLQPLDFIRKYYGEKIGIYFAWLGFYTNMLIVAAVVGVGCFLYGFFMKDNCTWSQEVCDPNIGGNIIMCPQCDKVCTYWNLTITCESSKKLCIFDSFGTLVFAVFMGIWVTLFLEFWKRRQAELEYEWDTVEYLEQEEQIRPEYEAQCTHVVVNEITQQEEHVPYTACGKCVRITLCTSAVFFWIFLIIASVIGIIVYRLSVFLVFSATLPRHINGTQAIRKYLTPQTATSVTASIISFIVIMVLNIVYEKVAILITDFELPRTQTEYENSLTTKMFLFQFVNYYSSCFYIAFFKGKFVGYPGNPVYWLGKYRNEECDPGGCLLELTTQLAIIVGGKAIWNNIQEVLLPWVKNLIGRYCADARSEKTVPRWEQDYHLQPIGKLGLFYEYLEMVIQFGFVTLFVASFPLAPLLALINNMLEIRLDAWKLTTQFRRMVPQKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGSHSSYTMRGYINNTLSVFSISDFKNASKPFSPWFGNHTTCRYRDFRYPPGHQHQYEHNIYYWHVIAAKLAFIIVMEHVIYFVKFIISYIIPDVSQETKSKVKREKYLTQKILHENDLKVVKKTIGKIADKIIEGVDSTFRPKTE", "length": 912, "header": "tr|A0A8V0YNL3-1|A0A8V0YNL3_CHICK Isoform 1 of Anoctamin OS=Gallus gallus OX=9031 GN=ANO6 PE=1 SV=1 CANONICAL=A0A8V0YNL3-1" }, "locus": { "chromosome": "1", "start_pos": 30806200, "end_pos": 30739935, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033097.1", "url": "https://www.ensembl.org/id/ENSGALT00010033097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019569.1", "url": "https://www.ensembl.org/id/ENSGALP00010019569.1" } ] } }, { "isoform_ac": "A0A8V0YTM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTM2/entry", "sequence": { "sequence": "MGRAADFDNKPDSLFFNDGQRRIDFVLVYEDETKMSHKRSNHKKQKRKRQVYESNLINNGLQLEATRSVLDEKTVFVKVHAPWEVLCTYAEVMHIKLPLQPNDLKTRESAFNWFTRLFRVDENIIKPEQEFFTAPFKREHLSNFYIQDKDTFFNPATRSRIVHFILSRVKYATKQNVKKFGINKLLDTGIYKAAFPLHDSSFGHLSTDPDCPSERYLLYREWAHPKNILKLQPLDFIRKYYGEKIGIYFAWLGFYTNMLIVAAVVGVGCFLYGFFMKDNCTWSQEVCDPNIGGNIIMCPQCDKVCTYWNLTITCESSKKLCIFDSFGTLVFAVFMGIWVTLFLEFWKRRQAELEYEWDTVEYLEQEEQIRPEYEAQCTHVVVNEITQQEEHVPYTACGKCVRITLCTSAVFFWIFLIIASVIGIIVYRLSVFLVFSATLPRHINGTQAIRKYLTPQTATSVTASIISFIVIMVLNIVYEKVAILITDFELPRTQTEYENSLTTKMFLFQFVNYYSSCFYIAFFKGKFVGYPGNPVYWLGKYRNEECDPGGCLLELTTQLAIIVGGKAIWNNIQEVLLPWVKNLIGRYCADARSEKTVPRWEQDYHLQPIGKLGLFYEYLEMVIQFGFVTLFVASFPLAPLLALINNMLEIRLDAWKLTTQFRRMVPQKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGSHSSYTMRGYINNTLSVFSISDFKNASKPFSPWFGNHTTCRYRDFRYPPGHQHQYEHNIYYWHVIAAKLAFIIVMEHVIYFVKFIISYIIPDVSQETKSKVKREKYLTQKILHENDLKVVKKTIGKIADKIIEGVDSTFRPKTE", "length": 860, "header": "tr|A0A8V0YTM2-1|A0A8V0YNL3_CHICK Computationally mapped isoform of Anoctamin OS=Gallus gallus OX=9031 GN=ANO6 PE=1 SV=1 CANONICAL=A0A8V0YNL3-1" }, "locus": { "chromosome": "1", "start_pos": 30806200, "end_pos": 30740014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033108.1", "url": "https://www.ensembl.org/id/ENSGALT00010033108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019572.1", "url": "https://www.ensembl.org/id/ENSGALP00010019572.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417802", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-GGA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AA94-1", "protein_name": "Anoctamin", "gene_name": "Ano6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQMMTRNVLLNMELEEDDDEDGDIGDVPDSRRPFLAPHTPLPSGLVLENFDQTIVCSTFGSLESQEDFRTPEFEEFNGKPDSLFFTDGQRRIDFVLVYEDESKKENNKKGTNEKQKRKRQAYESNLISHGLQLEATRSVSDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKTRSTFDTFNWFTKVLRVNESVIKPEQEFFTAPFEKSRMNDFYILDRDSFFNPATRSRIVYFILSRVKYQVMNNVNKFGINRLVSSGIYKAAFPLHDCKFNYKSEDPNCPSERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQPRPEYEAQCNHVVINEITQEEERIPFTTCGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGRLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLLHESHLKDLTKNMGLIAERIGGVADSSVRPKLE", "length": 932 }, "evidence": [ { "id": "A0A8V0YNL3", "url": "https://omabrowser.org/oma/group/A0A8V0YNL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QNZ8-1", "protein_name": "Anoctamin", "gene_name": "ano6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSETEDNDILEDSDTDGGDVEMADMIDSKTVQTCRTMPKGSDVPIVDFNGNQDFLFFNDGKRRIDFVLVYEYEESKNGSNKKASVIRRKKRRREFFEGSLMNKGLHLEMTQSVVDEKLFFVKLHMPFDVLCANAEVLHIKLPIKCNDLRTQSSKHNCCTKPFYPNEDVIGKEPDYFTAPFRKDLLNRFQLKEREGRELFTPTMRSRMVYYILSRAEYDIKGENKKFGITKLLAGGIYKAAYPLHDCRFNVKSKEEDCPNERYLLYSEWAHPKNFYKMQPLDLIRKYFGEKIGIYFAWLGFYTFMLSLAAAFGLGCFIYGYRSRESSTWSKEVCDPDIGGQIVMCPQCDNNCPYWRLNTTCESSKRLCVFDNFGTLVFAVFMSVWVTLFLEFWKRYQAKLEYKWDTVEFQQQEEQPRPEYEARCTYERFSPITQSNEKVPYTACGKCMRVSCGIGTVLFWILLIVASVVGVIVYRLAMFMVFSMQLRSDLNRKELEPFREYITPQMATSITASIINVIIIMILNIVYEKVAVWITDFELPRTKTEYENSLTLKMFLFQFVNFYSSCFYIAFFKGKIVGYPGEPVYWLGKFRNEECDPGGCLTELTTQLSIIMTGKAVWNNIQEVLLPWLKNLMFRHCTQVGSEKAIPRWEQDYQLQPMGTLGLFYEYLEMVIQFGFVTLFVASFPLAPLLALVNNLFEIRVDAWKFTTQFRRIVPEKAQDIGAWQPILQGVTILAVVTNTAIIAFTSDMIPRLVYYWAFSVSPYVENSNHTMAGFIDSSLSVFNISHFDDKTRPRDDIKPIWFNNITTCRYRDYRNPPDHQNPYQFNVYYWHVIAAKLAFMIVVEHIVYFTKFMLSYLIPDVPEALNEQIKRERFLTRDILNNSQLTDLIKPIREKLQTDVADFTELEELL", "length": 910 }, "evidence": [ { "id": "A0A8V0YNL3", "url": "https://omabrowser.org/oma/group/A0A8V0YNL3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4KMQ2-1", "protein_name": "Anoctamin-6", "gene_name": "ANO6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE", "length": 910 }, "evidence": [ { "id": "A0A8V0YNL3", "url": "https://omabrowser.org/oma/group/A0A8V0YNL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P9J9-1", "protein_name": "Anoctamin-6", "gene_name": "Ano6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQMMTRKVLLNMELEEDDDEDGDIVLENFDQTIVCPTFGSLENQQDFRTPEFEEFNGKPDSLFFTDGQRRIDFILVYEDESKKENNKKGTNEKQKRKRQAYESNLICHGLQLEATRSVSDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKTRSPFGNLNWFTKVLRVNESVIKPEQEFFTAPFEKSRMNDFYILDRDSFFNPATRSRIVYFILSRVKYQVMNNVNKFGINRLVSSGIYKAAFPLHDCRFNYESEDISCPSERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEAQCNHVVINEITQEEERIPFTTCGKCIRVTLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKNTDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKITKSKIKREKYLTQKLLHESHLKDLTKNMGIIAERIGGTVDNSVRPKLE", "length": 911 }, "evidence": [ { "id": "A0A8V0YNL3", "url": "https://omabrowser.org/oma/group/A0A8V0YNL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" }, { "name": "calcium-activated cation channel activity", "id": "GO:0005227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL3" } ], "pmid": "" }, { "name": "voltage-gated monoatomic ion channel activity", "id": "GO:0005244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005244", "evidence": [ { "database": "UniProtKB", 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"https://www.uniprot.org/uniprotkb/A0A8V0YNP8" } ] } ], "protein_names": [ { "name": "Mitochondrial import receptor subunit TOM22 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8/entry#names_and_taxonomy" } ] }, { "name": "Translocase of outer membrane 22 kDa subunit homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0YNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Central receptor component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOMM20, functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8#function" }, { "database": "UniProtKB", "id": "ARBA00094293", "url": "https://www.uniprot.org/uniprotkb/ARBA00094293#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOMM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8", "locus": { "chromosome": "1", "start_pos": 50884507, "end_pos": 50886799, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012772", "url": "https://www.ensembl.org/id/ENSGALG00010012772" } ] } } ], "crossref": [ { "id": "A0A8V0YNP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22884", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNP8", "url": "https://www.orthodb.org/?gene=A0A8V0YNP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12504:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12504:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGFTAWLCAGPLASGALTSLVLERSASFTWKLTLKRSLEPTSACFCVVFWGVAPPGRQGALCAAPSFRGRSVRTSASGGSLPAPSLVVVAVVVMAAPASLSPEELLPKGGAGKAEDLEDELEDDDDDEELDETLAERLWGLTEMFPESVRSAAGATFDLSLAIAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLSGKI", "length": 233, "header": "tr|A0A8V0YNP8-1|A0A8V0YNP8_CHICK Isoform 1 of Mitochondrial import receptor subunit TOM22 homolog OS=Gallus gallus OX=9031 GN=TOMM22 PE=1 SV=1 CANONICAL=A0A8V0YNP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8/entry", "sequence": { "sequence": "MPGFTAWLCAGPLASGALTSLVLERSASFTWKLTLKRSLEPTSACFCVVFWGVAPPGRQGALCAAPSFRGRSVRTSASGGSLPAPSLVVVAVVVMAAPASLSPEELLPKGGAGKAEDLEDELEDDDDDEELDETLAERLWGLTEMFPESVRSAAGATFDLSLAIAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLSGKI", "length": 233, "header": "tr|A0A8V0YNP8-1|A0A8V0YNP8_CHICK Isoform 1 of Mitochondrial import receptor subunit TOM22 homolog OS=Gallus gallus OX=9031 GN=TOMM22 PE=1 SV=1 CANONICAL=A0A8V0YNP8-1" }, "locus": { "chromosome": "1", "start_pos": 50886600, "end_pos": 50885214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030597.1", "url": "https://www.ensembl.org/id/ENSGALT00010030597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017751.1", "url": "https://www.ensembl.org/id/ENSGALP00010017751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "id": "A0A8V0YNQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YNQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YVJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43981:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43981:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77346", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRAVARVLRGLRGLRAPPVRALCAAAGTPPRGLLYERHGEPADVLHVPTRLKELELPALGHSDVLIKMLAAPINPADINMIQGTYALLAPLPAVAGSEGVGRVLEVGPGVVALSPGDCIIPADAGLGTWRTHAVLPEHSLLRVPGDVPLLCAATLSVNPCTAFRMLSDFESLAPGDSVIQNAANSGVGQAVIQIAKAMGIRTINVVRDRPDLPQLVERLLALGADHVVTEDALRKPEMKEIFKSIPKPRLALNCVGGRSTTEMLRHLQPKGTMVTYGGMAKQPVTVPVSAFIFRDVRLRGFWMTQWKKDHDKQSMASMVDTLCQMVQKGQLSAPACTAVPLEDFREALAASMQPFTSSKQILLL", "length": 365, "header": "tr|A0A8V0YNQ7-1|A0A8V0YNQ7_CHICK Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Gallus gallus OX=9031 GN=MECR PE=1 SV=1 CANONICAL=A0A8V0YNQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7/entry", "sequence": { "sequence": "MQRAVARVLRGLRGLRAPPVRALCAAAGTPPRGLLYERHGEPADVLHVPTRLKELELPALGHSDVLIKMLAAPINPADINMIQGTYALLAPLPAVAGSEGVGRVLEVGPGVVALSPGDCIIPADAGLGTWRTHAVLPEHSLLRVPGDVPLLCAATLSVNPCTAFRMLSDFESLAPGDSVIQNAANSGVGQAVIQIAKAMGIRTINVVRDRPDLPQLVERLLALGADHVVTEDALRKPEMKEIFKSIPKPRLALNCVGGRSTTEMLRHLQPKGTMVTYGGMAKQPVTVPVSAFIFRDVRLRGFWMTQWKKDHDKQSMASMVDTLCQMVQKGQLSAPACTAVPLEDFREALAASMQPFTSSKQILLL", "length": 365, "header": "tr|A0A8V0YNQ7-1|A0A8V0YNQ7_CHICK Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Gallus gallus OX=9031 GN=MECR PE=1 SV=1 CANONICAL=A0A8V0YNQ7-1" }, "locus": { "chromosome": "23", "start_pos": 3116711, "end_pos": 3111259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039229.1", "url": "https://www.ensembl.org/id/ENSGALT00010039229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022643.1", "url": "https://www.ensembl.org/id/ENSGALP00010022643.1" } ] } }, { "isoform_ac": "A0A8V0YVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ3/entry", "sequence": { "sequence": "MQRAVARVLRGLRGLRAPPVRALCAAAGTPPRGLLYERHGEPADVLQLKELELPALGHSDVLIKMLAAPINPADINMIQGTYALLAPLPAVAGSEGVGRVLEVGPGVVALSPGDCIIPADAGLGTWRTHAVLPEHSLLRVPGDVPLLCAATLSVNPCTAFRMLSDFESLAPGDSVIQNAANSGVGQAVIQIAKAMGIRTINVVRDRPDLPQLVERLLALGADHVVTEDALRKPEMKEIFKSIPKPRLALNCVGGRSTTEMLRHLQPKGTMVTYGGMAKQPVTVPVSAFIFRDVRLRGFWMTQWKKDHDKQSMASMVDTLCQMVQKGQLSAPACTAVPLEDFREALAASMQPFTSSKQILLL", "length": 361, "header": "tr|A0A8V0YVJ3-1|A0A8V0YNQ7_CHICK Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Gallus gallus OX=9031 GN=MECR PE=1 SV=1 CANONICAL=A0A8V0YNQ7-1" }, "locus": { "chromosome": "23", "start_pos": 3116711, "end_pos": 3111259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039226.1", "url": "https://www.ensembl.org/id/ENSGALT00010039226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022642.1", "url": "https://www.ensembl.org/id/ENSGALP00010022642.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-77346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77346", "resource": "Reactome", "description": "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA" } ], "orthologs": [ { "uniprot_canonical_ac": "P38071-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "ETR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLPTFKRYMSSSAHQIPKHFKSLIYSTHEVEDCTKVLSVKNYTPKQDLSQSIVLKTLAFPINPSDINQLQGVYPSRPEKTYDYSTDEPAAIAGNEGVFEVVSLPSGSSKGDLKLGDRVIPLQANQGTWSNYRVFSSSSDLIKVNDLDLFSAATVSVNGCTGFQLVSDYIDWNSNGNEWIIQNAGTSSVSKIVTQVAKAKGIKTLSVIRDRDNFDEVAKVLEDKYGATKVISESQNNDKTFAKEVLSKILGENARVRLALNSVGGKSSASIARKLENNALMLTYGGMSKQPVTLPTSLHIFKGLTSKGYWVTEKNKKNPQSKIDTISDFIKMYNYGHIISPRDEIETLTWNTNTTTDEQLLELVKKGITGKGKKKMVVLEW", "length": 380 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54YT4-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "mecr", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSTRNIISLVRRYSTSRSVKIASHGSPSTALKIENENITDKISNKDVLVEMLHAPINPADLNIIQGTYGTNVQVGGVAGMEGVGVVKKVGSGVTGLKENDLVVPSMKQHFGSWRSKGVWSEQQLFKVPSDIPTEYLSTISINPTTAYLLLNDFVKLQQGDVIIQNASNSMVGLSVIQLAKARGIKTINVIRDGSEFEDNVQRLKQLGGDIVVSEEYVRTPAFRKLISDLPSPKLALNAVGGQSATELSRILADNGTLVTYGGMSREPVTIPTSQLIFRNIQIRGFWLNKWFEQHTDSEKQSVYDAIFDLIRKKQFKLLIEKHKFSEFDQALLKSQQSGHGRKIVLDLQL", "length": 350 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6GQN8-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "mecr", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLPSVASLLIRVYRTTGPVSHIQRIRHGAVLNKNYSSVSAVKNCTALLYRNHGEPSQVVQLESLDLPQVGAECVLVKMLAAPINPSDLNMLQGTYAILPELPAVGGNEGVAQVMEVGDKVKTLKVGDWVIPKDAGIGTWRTAAVLKADDLVTLPKDIPVLSAATLGVNPCTAYRMLTDFEELKAGDTVIQNAANSGVGQAVIQIAAAKGIHTINVIRDRPDLRQLSDRLTAMGATHVITEETLRRPEMKELFKSCPRPKLALNGVGGKSATELLRHLQSGGSLVTYGGMAKQPVTVPVSALIFKDVRVRGFWVTQWKRDNRHDDEALRHMLDELCILIRAGKLSAPICTQVQLQDFRKALENAMKPYVSTKQVFVM", "length": 377 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8LCU7-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAALMESVVGRALKFSSTANFRSIRRGETPTLCIKSFSTIMSPPSKAIVYEEHGSPDSVTRLVNLPPVEVKENDVCVKMIAAPINPSDINRIEGVYPVRPPVPAVGGYEGVGEVYAVGSNVNGFSPGDWVIPSPPSSGTWQTYVVKEESVWHKIDKECPMEYAATITVNPLTALRMLEDFVNLNSGDSVVQNGATSIVGQCVIQLARLRGISTINLIRDRAGSDEAREQLKALGADEVFSESQLNVKNVKSLLGNLPEPALGFNCVGGNAASLVLKYLREGGTMVTYGGMSKKPITVSTTSFIFKDLALRGFWLQSWLSMGKVKECREMIDYLLGLARDGKLKYETELVPFEEFPVALDKALGKLGRQPKQVITF", "length": 375 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9BV79-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "MECR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM", "length": 373 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCS3-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "Mecr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLVSQRVTGARARAPQLAGLLEAWYRHGRTTSSYSALSEPSRVRALVYGNHGDPAKVVQLKNLELTAVEGSDVHVRMLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVIAVGSSVSALKPGDWVIPANAGLGTWRTEAVFSEEALIGIPKDIPLQSAATLGVNPCTAYRMLVDFEQLQPGDSVIQNASNSGVGQAVIQIASALRLKTINVVRDRPDIKKLTDRLKDLGADYVLTEEELRMPETKTIFKDLPLPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVTASVSLLIFKDLKLRGFWLSQWKKNHSPDEFKELILTLCNLIRQGRLTAPSCSEVPLQGYQQALEASMKPFVSSKQILTM", "length": 373 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V6U9-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "Mecr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRRGFLSRINAAQWSRQMSVVAKSLKYTQHGEPQEVLQLVEDKLPDPKDNQVLVKILAAPINPADINTIQGKYPVKPKFPAVGGNECVAEVICVGDKVKGFEAGQHVIPLASGLGTWTTHAVYKEDQLLIVSKKVGLAEAATSTVNPTTAYRMLKDFVQLCPGDTVIQNGANSAVGQAVHQLCRAWGINSVGIVRDRPEIAELKQMLQCLGATEVLTEAEIRTSDIFKSGKLKKPRLAFNCVGGKSATEVSRHLDNGGVLVTYGGMSREPVTVATGPLIFKDIAFRGFWMTRWSKENYSSPERSKMFKEIFELMEQGKFVAPNHEMVPLAKFKDAAAAALSFKGFTGKKYILDMSI", "length": 357 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z311-1", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "Mecr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVSRRLTGARARAPLLASLLEAWCRQGRTTSSYSAFSEPSHVRALVYGNHGDPAKVIQLKNLELTAVEGSDVHVKMLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVIAVGSSVSGLKPGDWVIPANAGLGTWRTEAVFSEEALIGVPKDIPLQSAATLGVNPCTAYRMLVDFEQLQPGDSVIQNASNSGVGQAVIQIASALGLKTINVIRDRPDIKKLTDRLKDLGADYVLTEEELRMPETKNIFKDLPLPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVTASVSMLIFKDLKLRGFWLSQWKKNHSPDEFKELILILCNLIRQGQLTAPAWSGIPLQDYQQALEASMKPFVSLKQILTM", "length": 373 }, "evidence": [ { "id": "A0A8V0YNQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YNQ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNQ7-1" ], "evidence": [ { "id": "R-GGA-8952873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8952873" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YNQ7", "gene_name": "MECR", "activity": [ { "ec_number": "1.3.1.104", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0A8V0YNQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ] }, { "ec_number": "1.3.1.104", "activity": "", "evidence": [ { "id": "A0A8V0YNQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNQ7" }, { "id": "SM00829", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enoyl reductase (ER)", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 363, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.1.104", "ec_name": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "1.3.1.104", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.104" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNR6-1", "uniprot_ac": "A0A8V0YNR6", "uniprot_id": "A0A8V0YNR6_CHICK", "mass": { "chemical_mass": 22200.0, "monoisotopic_mass": 22200.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YNR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YNR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR6", "url": 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"MDLSPLPGARVSVCQDVGLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGEAGFPGVLLFAPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPPAYVPYRIPRKGVRGDPGSPGASGLRGEQGEQGDRGLPGIPGFSDGDADKPGLPGEIGPKGEKGEEGSPAYQAGPPGFPGKHGEPGIRGPPGPPGTPGSLFGLKGQEGTPGRPGVQGFPGPRGQRGPKGEEGDCSKCLLSDELRRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGLPGPKGEKGDSIYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGEIGLPGEGYPGPKGYRGLPGDRGTDGHPGPPGLPGPPGEPGQLDCGQVIEDFSRGEATDPVWSGGGCVRPPKGSQGNPGLPGATGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDRGPNGLPGLQGHPGLMGKSGAPGLAGQKGAPGDVLGAAAGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGTPGTHGFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPGPVGMKGLSGDKGETGFPGLQGIPGVTGPPGISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPGEPPKLKPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTGLKGYPGPTGSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQKGLPGLVGPPGQQGSPGTPGFQGEKGAPGWPGLPGQAGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVEGSQGPPGQKGDRGVPGVQGPFGIPGQDGLPGPPGISNISGYPGDTGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDPGLPGRPGIPGYPGPKGRKGEQGVIGFIGTIGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPIPPRLVAEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGFEGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL", "length": 1715, "header": "tr|A0A8V0YNS3-1|A0A8V0YNS3_CHICK Isoform 1 of Collagen type IV alpha 2 chain OS=Gallus gallus OX=9031 GN=COL4A2 PE=1 SV=1 CANONICAL=A0A8V0YNS3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3/entry", "sequence": { "sequence": "MDLSPLPGARVSVCQDVGLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGEAGFPGVLLFAPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPPAYVPYRIPRKGVRGDPGSPGASGLRGEQGEQGDRGLPGIPGFSDGDADKPGLPGEIGPKGEKGEEGSPAYQAGPPGFPGKHGEPGIRGPPGPPGTPGSLFGLKGQEGTPGRPGVQGFPGPRGQRGPKGEEGDCSKCLLSDELRRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGLPGPKGEKGDSIYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGEIGLPGEGYPGPKGYRGLPGDRGTDGHPGPPGLPGPPGEPGQLDCGQVIEDFSRGEATDPVWSGGGCVRPPKGSQGNPGLPGATGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDRGPNGLPGLQGHPGLMGKSGAPGLAGQKGAPGDVLGAAAGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGTPGTHGFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPGPVGMKGLSGDKGETGFPGLQGIPGVTGPPGISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPGEPPKLKPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTGLKGYPGPTGSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQKGLPGLVGPPGQQGSPGTPGFQGEKGAPGWPGLPGQAGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVEGSQGPPGQKGDRGVPGVQGPFGIPGQDGLPGPPGISNISGYPGDTGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDPGLPGRPGIPGYPGPKGRKGEQGVIGFIGTIGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPIPPRLVAEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGFEGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL", "length": 1715, "header": "tr|A0A8V0YNS3-1|A0A8V0YNS3_CHICK Isoform 1 of Collagen type IV alpha 2 chain OS=Gallus gallus OX=9031 GN=COL4A2 PE=1 SV=1 CANONICAL=A0A8V0YNS3-1" }, "locus": { "chromosome": "1", "start_pos": 139060348, "end_pos": 138920050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034533.1", "url": "https://www.ensembl.org/id/ENSGALT00010034533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020282.1", "url": "https://www.ensembl.org/id/ENSGALP00010020282.1" } ] } }, { "isoform_ac": "A0A8V0YQH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQH5/entry", "sequence": { "sequence": "MDLSPLPGARVSVCQDVGLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGEAGFPGVLLFAPEKGEEGVMGFPGQRVSCSLKVKFVLLNMQVQAETLSLGAKHREISHRNESSSAHAFQVLASFELPDMGKEK", "length": 362, "header": "tr|A0A8V0YQH5-1|A0A8V0YNS3_CHICK Computationally mapped isoform of Collagen type IV alpha 2 chain OS=Gallus gallus OX=9031 GN=COL4A2 PE=1 SV=1 CANONICAL=A0A8V0YNS3-1" }, "locus": { "chromosome": "1", "start_pos": 139021990, "end_pos": 138920050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034512.1", "url": "https://www.ensembl.org/id/ENSGALT00010034512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020273.1", "url": "https://www.ensembl.org/id/ENSGALP00010020273.1" } ] } }, { "isoform_ac": "A0A8V0YQI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI0/entry", "sequence": { "sequence": "MILQPFNGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGEAGFPGVLLFAPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPPAYVPYRIPRKGVRGDPGSPGASGLRGEQGEQGDRGLPGIPGFSDGDADKPGLPGEIGPKGEKGEEGSPAYQAGPPGFPGKHGEPGIRGPPGPPGTPGSLFGLKGQEGTPGRPGVQGFPGPRGQRGPKGEEGDCSKCLLSDELRRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGLPGPKGEKGDSIYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGEIGLPGEGYPGPKGYRGLPGDRGTDGHPGPPGLPGPPGEPGQLDCGQVIEDFSRGEATDPVWSGGGCVRPPKGSQGNPGLPGATGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDRGPNGLPGLQGHPGLMGKSGAPGLAGQKGAPGDVLGAAAGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGTPGTHGFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPGPVGMKGLSGDKGETGFPGLQGIPGVTGPPGISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPGEPPKLKPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTGLKGYPGPTGSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQKGLPGLVGPPGQQGSPGTPGFQGEKGAPGWPGLPGQAGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVEGSQGPPGQKGDRGVPGVQGPFGIPGQDGLPGPPGISNISGYPGDTGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDPGLPGRPGIPGYPGPKGRKGEQGVIGFIGTIGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPIPPRLVAEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGFEGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL", "length": 1687, "header": "tr|A0A8V0YQI0-1|A0A8V0YQI0_CHICK Computationally mapped isoform of Collagen type IV alpha 2 chain OS=Gallus gallus OX=9031 GN=COL4A2 PE=1 SV=1 CANONICAL=A0A8V0YNS3-1" }, "locus": { "chromosome": "1", "start_pos": 139060348, "end_pos": 138949746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034526.1", "url": "https://www.ensembl.org/id/ENSGALT00010034526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020278.1", "url": "https://www.ensembl.org/id/ENSGALP00010020278.1" } ] } }, { "isoform_ac": "A0A8V0YVL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVL5/entry", "sequence": { "sequence": "MDLSPLPGARVSVCQDVGLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGEAGFPGVLLFAPEKGEEGVMGFPGQRGLPGNDGFPGLSGERHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL", "length": 404, "header": "tr|A0A8V0YVL5-1|A0A8V0YNS3_CHICK Computationally mapped isoform of Collagen type IV alpha 2 chain OS=Gallus gallus OX=9031 GN=COL4A2 PE=1 SV=1 CANONICAL=A0A8V0YNS3-1" }, "locus": { "chromosome": "1", "start_pos": 139060348, "end_pos": 138920050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034541.1", "url": "https://www.ensembl.org/id/ENSGALT00010034541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020286.1", "url": "https://www.ensembl.org/id/ENSGALP00010020286.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1058, "start_aa": "Thr", "end_pos": 1058, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1058", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1172, "start_aa": "Thr", "end_pos": 1172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1172", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 445, "start_aa": "Thr", "end_pos": 445, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr445", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 840, "start_aa": "Thr", "end_pos": 840, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr840", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418752", "resource": "KEGG Pathway" }, { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1566977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566977", "resource": "Reactome", "description": "Fibronectin matrix formation" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-186797", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186797", "resource": "Reactome", "description": "Signaling by PDGF" }, { "id": "R-GGA-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-2243919", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2243919", "resource": "Reactome", "description": "Crosslinking of collagen fibrils" }, { "id": "R-GGA-3000171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "resource": "Reactome", "description": "Non-integrin membrane-ECM interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M6Q3-1", "protein_name": "Collagen type IV alpha 2 chain", "gene_name": "Col4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRVRFSASGLPLRGWLLLATVTVGLLAQSVLGGVKKSDVPCGGRDCSGGCQCFPEKGARGQPGEVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGTGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDITLIGPTPSTYHPDMYKGEKGSQGEPGIPGITLKGEEGIMGFPGTRGFPGLDGEKGVSGQKGSRGLDGFQGPSGPRGPKGERGELGPPGPPAYSPHPSLAKGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLSIGDEDSKRGLPGEMGPKGFSGEPGPSAYYPGPPGADGKPGPQGLPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGDCQCGQVIPGLPGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSRTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVVIQPGCVEGPAGSPGQPGPPGPTGAKGIRGIPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAPGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPGMKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQGQPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL", "length": 1707 }, "evidence": [ { "id": "A0A8V0YNS3", "url": "https://omabrowser.org/oma/group/A0A8V0YNS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RLL9-1", "protein_name": "Collagen type IV alpha 2 chain", "gene_name": "COL4A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRDPRAASGPALRRWLLLGTVMVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGSDGCNGTVGDTGYAGPVGPDGFLGPPGPQGPKGQKGEPYALSREDRDKYRGEPGEPGLVGFQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDNHHPIIGPTRETIYLDQYKGEKGSEGEPGRKGISLKGEEGIMGFSGSRGVPGFDGEKGSPGQKGSRGLDGYEGPDGYPGPKGERGDPGPPGAPAYSPHPSLAKGARGEPGFPGALGEPGARGEPGDPGPPGLPGTSVRDEDEKRGLPGEMGPKGYAGEPGAPALYPGPPGADGKPGLRGPPGPPGPPGPDDFLFGLKGAKGSMGYPGPSGFPGARGQKGWKGDAGDCKCAEDDQFVGGLPGPPGPKGFPGINGEPGRKGSQGDPGQHGIPGFPGFKGAPGDAGPPGPKGMKGDSRTITTKGERGQPGVPGVPGLRGDDGAPGRDGLDGFPGLPGPPGDGIKGPPGDAGHPGVPGTKGLAGDRGPPGLGLPGPKGERGFPGDDGLPGPPGFPGPPGPPGPPGQIDCDSGVKRPIGADGQEVIQPGCVGGPKGSPGQPGPPGPPGAKGLRGIPGPSGADGAPGLKGFPGDPGREGFPGPPGFVGPRGSKGAVGPPGLDGLPGPSGLPGPVGPPGDKGLPGEVLGAQPGSRGDPGLPGHPGLKGPPGERGAPGFRGSEGMPGMPGLKGQPGFPGPSGQPGLPGPPGQHGFPGAPGREGPLGPPGAPGFGGLPGDRGDPGDTGVPGPVGMKGLSGDRGDPGLLGERGHPGSPGFKGVAGMPGAPGPKGTRGSPGMHGFQGMLGLKGSPGLPGSKGEAGFFGVPGLKGLPGEPGVKGSRGDPGLPGPPPTILPGMKDIKGEKGDEGPMGLKGYLGLKGIPGMPGIPGLSGVPGLPGKPGHVKGAKGDTGAPGVPGSPGFPGLPGPPGIIGFPGFTGSRGDKGSPGRAGLYGEIGATGDFGDIGDTIDLPGSPGLKGERGTAGVPGLKGFFGEKGTVGDVGFPGITGLAGVQGPPGLKGQTGFPGLTGLQGPQGDPGRAGVPGAKGELGWPGNVGLPGLPGIRGISGLHGLPGTKGFPGSPGADVHGDPGFPGPAGDRGDPGEANTLPGPAGAPGQKGERGAPGERGPVGNPGLQGFPGITPPSNVSGLPGDTGAPGIFGPEGYRGPPGPPGPAALPGSKGDEGLPGIPGNPGGKGWVGDPGPQGRPGVFGLPGEKGPRGEQGFMGNTGATGSVGDRGPKGPKGDRGLPGPPGAVGAPGIVGIPQRIAVQRGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPVGQQGPVGQEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICHYASRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQSFQSSPSADTLKAGLIRTHISRCQVCMKNL", "length": 1712 }, "evidence": [ { "id": "A0A8V0YNS3", "url": "https://omabrowser.org/oma/group/A0A8V0YNS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08122-1", "protein_name": "Collagen alpha-2(IV) chain", "gene_name": "Col4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRVRFKASGPPLRGWLLLATVTVGLLAQSVLGGVKKLDVPCGGRDCSGGCQCYPEKGARGQPGAVGPQGYNGPPGLQGFPGLQGRKGDKGERGVPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGSGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGLVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGQKGEKGDIGQPGPNGIPSDITLVGPTTSTIHPDLYKGEKGDEGEQGIPGVISKGEEGIMGFPGIRGFPGLDGEKGVVGQKGSRGLDGFQGPSGPRGPKGERGEQGPPGPSVYSPHPSLAKGARGDPGFQGAHGEPGSRGEPGEPGTAGPPGPSVGDEDSMRGLPGEMGPKGFSGEPGSPARYLGPPGADGRPGPQGVPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGTRGQKGWKGEAGDCQCGQVIGGLPGLPGPKGFPGVNGELGKKGDQGDPGLHGIPGFPGFKGAPGVAGAPGPKGIKGDSRTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGVPGTKGFPGDIGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGPPGTPGQRDCDTGVKRPIGGGQQVVVQPGCIEGPTGSPGQPGPPGPTGAKGVRGMPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGTTGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGTRGDAGLPGQPGLKGLPGETGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGQSGPPGQHGFPGTPGREGPLGQPGSPGLGGLPGDRGEPGDPGVPGPVGMKGLSGDRGDAGMSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRQGFPGTKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPGMKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGVSGFPGLPGRPGFIKGVKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGITGIPGLKGFFGEKGAAGDIGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGLPGFPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGVPGQKGERGTPGERGPAGSPGLQGFPGISPPSNISGSPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGQKGWVGDPGPQGQPGVLGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTLGPQGRRGLPGALGEIGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDTSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL", "length": 1707 }, "evidence": [ { "id": "A0A8V0YNS3", "url": "https://omabrowser.org/oma/group/A0A8V0YNS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P08572-1", "protein_name": "Collagen alpha-2(IV) chain", "gene_name": "COL4A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL", "length": 1712 }, "evidence": [ { "id": "A0A8V0YNS3", "url": "https://omabrowser.org/oma/group/A0A8V0YNS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" }, { "name": "collagen-activated tyrosine kinase receptor signaling pathway", "id": "GO:0038063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" }, { "name": "collagen type IV trimer", "id": "GO:0005587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" }, { "name": "collagen trimer", "id": "GO:0005581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1279, "end_pos": 1281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNS3" }, { "id": "PS51403", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51403" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Collagen IV NC1", "eco_id": "ECO_0000259", "start_pos": 1493, "end_pos": 1715, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 151, 445, 458, 508, 840, 1058, 1172 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1279, "end_pos": 1281 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 722, "end_pos": 724 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNU0-1", "uniprot_ac": "A0A8V0YNU0", "uniprot_id": "A0A8V0YNU0_CHICK", "mass": { "chemical_mass": 73827.0, "monoisotopic_mass": 73827.0 }, "refseq": {}, "gene_names": [ { "name": "LSG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ] } ], "protein_names": [ { "name": "Large subunit GTPase 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YNU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as a GTPase. May act by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm during the 60S ribosomal subunit maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0#function" }, { "database": "UniProtKB", "id": "ARBA00093349", "url": "https://www.uniprot.org/uniprotkb/ARBA00093349#function" }, { "database": "UniProtKB", "id": "A0A8V0YQJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LSG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0", "locus": { "chromosome": "9", "start_pos": 12516798, "end_pos": 12503209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014344", "url": "https://www.ensembl.org/id/ENSGALG00010014344" } ] } } ], "crossref": [ { "id": "A0A8V0YNU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01857", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01857", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNU0", "url": "https://www.orthodb.org/?gene=A0A8V0YNU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45709:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45709:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKRGTGLGRSLQRQRGSERRGASSWLHASEVVGESGPERRSAVEQSPLEEFLATAELAGTRFVAERLNIQFVSAQSRTGLLTAQEAQHVRQLHEENRQFLRIPRRPYWDRTTSSEDLKQAERESFLEWRRQLAHLEEEKKLILTPFERNLEFWRQLWRVIERSDIVVQIVDARNPLLFRCQDLESYVKEVSNDKENMILINKADLLSEEQRAAWAQFFEKEGVKVVFWSALAECRRLSGEVKELDADSVADDLNDSEEESSSQEEDVTAEDSAESTSTGSALQTENQCLLSDDDSSDEYEDCEDEEEDDWQTCSEDEGGDKVNAIAPKSVENRTDIVAMHHVVQEQNRNVKNFSHLVQRNELLEIFKTLHSGPRVKDGEVNVGLVGYPNVGKSSTINTILGDKKVSVSATPGRTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPPISLISFHIPRNILEATYGINIIRPREDEDPDRKPTAEELLTAYGYMRGFMTAHGQPDQPRSARYVLKDYVSGKLLYCHPPPGIDPDGFQHQHERCPESRTVQASGPVKPKKNTKAKQIENVVDKSFFHQENVRALMKGVRATMGYRPGSGLVSVPAPSAGSVVGKPWKKHGNRNKKEKVRRITKHLEN", "length": 653, "header": "tr|A0A8V0YNU0-1|A0A8V0YNU0_CHICK Isoform 1 of Large subunit GTPase 1 homolog OS=Gallus gallus OX=9031 GN=LSG1 PE=4 SV=1 CANONICAL=A0A8V0YNU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0/entry", "sequence": { "sequence": "MGKKRGTGLGRSLQRQRGSERRGASSWLHASEVVGESGPERRSAVEQSPLEEFLATAELAGTRFVAERLNIQFVSAQSRTGLLTAQEAQHVRQLHEENRQFLRIPRRPYWDRTTSSEDLKQAERESFLEWRRQLAHLEEEKKLILTPFERNLEFWRQLWRVIERSDIVVQIVDARNPLLFRCQDLESYVKEVSNDKENMILINKADLLSEEQRAAWAQFFEKEGVKVVFWSALAECRRLSGEVKELDADSVADDLNDSEEESSSQEEDVTAEDSAESTSTGSALQTENQCLLSDDDSSDEYEDCEDEEEDDWQTCSEDEGGDKVNAIAPKSVENRTDIVAMHHVVQEQNRNVKNFSHLVQRNELLEIFKTLHSGPRVKDGEVNVGLVGYPNVGKSSTINTILGDKKVSVSATPGRTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPPISLISFHIPRNILEATYGINIIRPREDEDPDRKPTAEELLTAYGYMRGFMTAHGQPDQPRSARYVLKDYVSGKLLYCHPPPGIDPDGFQHQHERCPESRTVQASGPVKPKKNTKAKQIENVVDKSFFHQENVRALMKGVRATMGYRPGSGLVSVPAPSAGSVVGKPWKKHGNRNKKEKVRRITKHLEN", "length": 653, "header": "tr|A0A8V0YNU0-1|A0A8V0YNU0_CHICK Isoform 1 of Large subunit GTPase 1 homolog OS=Gallus gallus OX=9031 GN=LSG1 PE=4 SV=1 CANONICAL=A0A8V0YNU0-1" }, "locus": { "chromosome": "9", "start_pos": 12514771, "end_pos": 12503237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034562.1", "url": "https://www.ensembl.org/id/ENSGALT00010034562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020297.1", "url": "https://www.ensembl.org/id/ENSGALP00010020297.1" } ] } }, { "isoform_ac": "A0A8V0YQJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ7/entry", "sequence": { "sequence": "MGKKRGTGLGRSLQRQRGSERRGASSWLHASEVVGESGPERRSAVEQSPLEEFLATAELAGTRFVAERLNIQFVSAQSRTGLLTAQEAQHVRQLHEENRQFLRIPRRPYWDRTTSSEDLKQAERESFLEWRRQLAHLEEEKKLILTPFERNLEFWRQLWRVIERSDIVVQIVDARNPLLFRCQDLESYVKEVSNDKENMILINKADLLSEEQRAAWAQFFEKEGVKVVFWSALAECRRLSGEVKELDADSVADDLNDSEEESSSQEEDVTAEDSAESTSTGSALQTENQCLLSDDDSSDEYEDCEDEEEDDWQTCSEDEGGDKVNAIAPKSVENRTDIVAMHHVVQEQNRNVKNFSHLVQRNELLEIFKTLHSGPRVKDGEVNVGLVGYPNVGKSSTINTILGDKKVSVSATPGRTKHFQHIPRNILEATYGINIIRPREDEDPDRKPTAEELLTAYGYMRGFMTAHGQPDQPRSARYVLKDYVSGKLLYCHPPPGIDPDGFQHQHERCPESRTVQASGPVKPKKNTKAKQIENVVDKSFFHQENVRALMKGVRATMGYRPGSGLVSVPAPSAGSVVGKPWKKHGNRNKKEKVRRITKHLEN", "length": 602, "header": "tr|A0A8V0YQJ7-1|A0A8V0YNU0_CHICK Computationally mapped isoform of Large subunit GTPase 1 homolog OS=Gallus gallus OX=9031 GN=LSG1 PE=4 SV=1 CANONICAL=A0A8V0YNU0-1" }, "locus": { "chromosome": "9", "start_pos": 12514771, "end_pos": 12503237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034554.1", "url": "https://www.ensembl.org/id/ENSGALT00010034554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020293.1", "url": "https://www.ensembl.org/id/ENSGALP00010020293.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 412, "start_aa": "Thr", "end_pos": 412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr412", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", 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"MDEQDNDFKELWANLLGKGKKKPGDAEAAKRAQKRSKNTAAKSKLRRGKAAAKSQNHHLFPAAKQKSLLQDLGPKIQTLGHKEDSDTVACSSGETSEGDGSRSPFPASQLSTTASDCSQGTLTVNTRSGCSQTTLSFHPATQSGTCSSPTSKIPPFTGSKVRVAELVVERMQQFKRVAPDQLKHSTDCSLPKSLASGDFAGESQEQNSPESDLHDLPSMQHDGALALALQQETQKESLESLEDAGLFFCQICQKDLSAMNSTRREQHVNRCLDEMEEAQMSSSSKPAVPECPICGKQFQTPQSRVSHLKRCAVEMDVPPKMLLQAVQMQVSTLGEAPLQFPNNQPSRSKRKVSTKEDSKNKQKRAKMETKDEDLLVAMAMSRSLLEQEKQEQAKLVTNVKPVAALPIKWKPGSEKRRRKRGPTTPPPLLLQDPEKVRRRIEERVAMLLAQEMEFPPTPRLPTSRILEVEAGKAAWLLPLPKNKDCFLWNFSALTGPCDPESFYAAGLTPPIEPWKPVQSSLRSLAEDFSAMVNNPHLSDVQFQVDSGEVLYAHMFVLYARCPQAIQTVHSEGFLVEEDGNAQIRRVLLSDVTGEAARAFLRYLYAADADIPAEVVPQVGALAARFGVRELMAKCENNTGESQVSSGVDSESDLISVTDDKDCEDRAENFQDLLKSVWVGEDEEEAAVLNQECQKEDDNAVGEQELEEIYEFAATQRRMVQGKTTPSEGTDCSMCSDTEAAQDMNQQTEEEEVKRSVSSSVSSNFKDLRDNNDVEISRCDLSAEKEGMQNINRCRSVNATQITSVPNHREPQKRDVASRGATTDEGETIKRCEGGKDSRSSQVSHDVKGEDRCEKEVLSFTTDTNINGSYEHLFSATQGDYCEPSPTKEVSKVSEKALGEKHADVNEFHLYSEIQKDFSPHKNGSYGSPSSKAFVPLFPAVGSSPLSPKSDRKLEREHVSTPKQKKKSLPPVEIHFQKASELDAASPPGLPNTDLNKHVPVLSAPVIRTQDPAAQGSKKGDVIVLSSDDEMELEDKKSLESGSVLKDVEIPGQLKGINIGHGPEIPKPEHNTSVTKTEQRSLQVSNVITDKVHVSNDVKMSTELPLSSHVDACTEGEQSPNLSPEKTLCHEVSSGTDSSWLVPDTPVLTKSRSSSTQTHVTSINSSKSPESKVSTKNLAADISNHEMDRNVIGVHKAALSDEHLPVENCVSERSPSSSPGAGSVPEKPTPLSSVDPVLSLAHSNSKSKSANTSFLSKLVPPCHGKSIEDKSNVSVVEIQDSEGEKETSIASLSSSVLLADEPAIPADDCWHAKCLSPVRGNSQDSRQDGHANTRAASSPKTDFVHDQWDSPDQAWEIKGSTPVQGTPVGRRTSLLRLEKSPIEACTSVGSRLSYLNSRLWDNWDGEEEEDEFPEVLPLSQRVSAAAREDPVKTPEPACQENNNSPRTPVTPMPAYSMMETPQLKDELKRFGVRALPKRQMVLKLKEIFQYTHRDVDSDFEDEVPSSQPPQKKSPPKHCRQSKAAQTTGGKRPRASKAASKRKQVATGSSVLPVGRSEDDLVGPSEKGCAAPKQRNEMEHHPEGDKEQKRSAVSPEGWSLGADGEEPMLSASQESAATSGDGSDISFGSQSSFVKELETGAFASEEEEEELPASQAAAREEEKLEAVRCYIRSNPALYDRILFYEPIELADLHAELKLNGIKISKAKLLDFLDAQCITFTTAGARKEKEQKRKGSRKKRKRY", "length": 1740, "header": "tr|A0A8V0YNU3-1|A0A8V0YNU3_CHICK Isoform 1 of Structure-specific endonuclease subunit SLX4 OS=Gallus gallus OX=9031 GN=SLX4 PE=3 SV=1 CANONICAL=A0A8V0YNU3-1" }, "locus": { "chromosome": "14", "start_pos": 12466671, "end_pos": 12445465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039319.1", "url": "https://www.ensembl.org/id/ENSGALT00010039319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022679.1", "url": "https://www.ensembl.org/id/ENSGALP00010022679.1" } ] } }, { "isoform_ac": "A0A8V0YX88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX88/entry", "sequence": { "sequence": "MHSRSDACAYMRTSEPACQENNNSPRTPVTPMPAYSMMETPQLKDELKRFGVRALPKRQMVLKLKEIFQYTHRDVDSDFEDEVPSSQPPQKKSPPKHCRQSKAAQTTGGKRPRASKAASKRKQVATGSSVLPVGRSEDDLVGPSEKGCAAPKQRNEMEHHPEGDKEQKRSAVSPEGWSLGADGEEPMLSASQESAATSGDGSDISFGSQSSFVKELETGAFASEEEEEELPASQAAAREEEKLEAVRCYIRSNPALYDRILFYEPIELADLHAELKLNGIKISKAKLLDFLDAQCITFTTAGARKEKEQKRKGSRKKRKRY", "length": 321, "header": "tr|A0A8V0YX88-1|A0A8V0YNU3_CHICK Computationally mapped isoform of Structure-specific endonuclease subunit SLX4 OS=Gallus gallus OX=9031 GN=SLX4 PE=3 SV=1 CANONICAL=A0A8V0YNU3-1" }, "locus": { "chromosome": "14", "start_pos": 12448214, "end_pos": 12445465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039307.1", "url": "https://www.ensembl.org/id/ENSGALT00010039307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022672.1", "url": "https://www.ensembl.org/id/ENSGALP00010022672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "positive regulation of t-circle formation", "id": "GO:1904431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "telomeric D-loop disassembly", "id": "GO:0061820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "t-circle formation", "id": "GO:0090656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090656", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "DNA double-strand break processing involved in repair via single-strand annealing", "id": "GO:0010792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "negative regulation of telomere maintenance via telomere lengthening", "id": "GO:1904357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "ERCC4-ERCC1 complex", "id": "GO:0070522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "Holliday junction resolvase complex", "id": "GO:0048476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "Slx1-Slx4 complex", "id": "GO:0033557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033557", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1120, "end_pos": 1122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1250, "end_pos": 1252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1441, "end_pos": 1443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YNX2-1" }, "locus": { "chromosome": "1", "start_pos": 48171350, "end_pos": 48169117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034698.1", "url": "https://www.ensembl.org/id/ENSGALT00010034698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020359.1", "url": "https://www.ensembl.org/id/ENSGALP00010020359.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 17, "start_aa": "Thr", "end_pos": 17, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr17", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": 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"id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX2" }, { "id": "PS51504", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51504" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "H15", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 113, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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"MIGGFGGQMIPVTQTWLKLGVGRLPPREYKVSIAPIPEYILGIDILSGLTLQTTVGEFRLRERCISIRAVQAIIRGHAEIEPICLPQPRRVTNTKQYRLPGGQQEITKTVQELERVGIIRPAHSPYNSPIWPVRKPDGTWRMTVDYRELNKVTPPIHAAVPNIASLMDTLSREIETYHCVLDLANAFFSIPIAKESQDQFAFTWEGRQWTFQVLPQGYVHSPTFCHNLVARDLANWNKPSTVKMFHYIDDLMLTSDSIEALEKTVPSLITYLQEKGWAINPQKVQGPGLSVKFLGVVWSGKTKVLPSAIIDKIQAFPVPTKPKQLQEFLGILGYWRSFIPHLAQLLKPLYQLTKKGQVWDWGRTEQEAFQQAKIAVKQAQALGICDPTLPAELDVHVTQEGFGWGLWQRQSSVRIPIGFWSQIWHGAEERYSMVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYLSQRSRLSSSPLKEELQKILVPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHRKLRHAGQKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTASGLMQAYPVAKANQASTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLKGWTKRLYETLRDLNERPRDGRPSALKMLQTTWASPLRIQITSKDNSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVVVDTPVFIARGTLIMSMWQIRTPPLVPDIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYFP", "length": 1068, "header": "tr|A0A8V0YNX5-1|A0A8V0YNX5_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YNX5-1" }, "locus": { "chromosome": "W", "start_pos": 6586790, "end_pos": 6583587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030767.1", "url": "https://www.ensembl.org/id/ENSGALT00010030767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017842.1", "url": "https://www.ensembl.org/id/ENSGALP00010017842.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 748, "end_pos": 914, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YNX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 681, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YNX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX5" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 298, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNX6-1", "uniprot_ac": "A0A8V0YNX6", "uniprot_id": "A0A8V0YNX6_CHICK", "mass": { "chemical_mass": 123924.0, "monoisotopic_mass": 123924.0 }, "refseq": { "ac": "XP_046792589", "name": "uncharacterized protein LOC112532140 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792589" }, "gene_names": [ { "name": "LOC112532140", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6" } ] }, { "name": "LOC112532140", "type": "synonym", "evidence": [ { "id": "XP_046792589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792589" } ] } ], "protein_names": [ { "name": "Gag polyprotein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC112532140 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046792589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792589" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046792589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792589" } ] }, { "annotation": "Binds strongly to viral nucleic acids and promotes their packaging. Plays a role in the maturation-stabilization of the viral dimeric RNA via highly structured zinc-binding motifs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6#function" }, { "database": "UniProtKB", "id": "ARBA00045783", "url": "https://www.uniprot.org/uniprotkb/ARBA00045783#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112532140", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6", "locus": {} } ], "crossref": [ { "id": "cd05482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09949", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09949", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112532140", "url": "https://www.ncbi.nlm.nih.gov/gene/112532140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNX6", "url": "https://www.orthodb.org/?gene=A0A8V0YNX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40389:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40389:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02813", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02813", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046792589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQVIKVLVQFCKDYCGKSTPSRKEIATVLSLLNELGELDSPRHILDSNRWDLLTSALCQRAMASQKATELKTWGLMLGALKAARAEHKLGAVMSGEGAPGSGSLEFCRTGAPTGAPTGAPTGAQTTANKTATEREEDCEKEDCEKDNEESQRLGGGATTPTAPPNSIALSPPPPYPKQPLYPSLATTSEQGAGPSPKGKGEGRLKLTDWGQIKEEVAQKGLAATYTLPVVVSEEGGPIWVPLDPKGVARMIEAVEKKGLKSPLTMNALEALTASGPVLPYDIENLMRMVLKPVQYTLWREEWHTKLKQMLIMAQGDQRNPIYGSDIQRLTGNAPGLLTPQAQVCQLRPGELIATTDAAIDAFRKLARSAEPTTPWTEIAQGPTEPFQEFADRLIKAVEGSDLPRAVHGPVILDCLYQKSSEGVQGILRAAPGRLQTPGEAIKYVLDKQKACPSVAGEVAAAVAGVMMACREADHRSADRQLGPCFKCGQLGHIRAQCRMGTGGGVTCQQCGRKGHTAPQCRARRPPRQGNNNGRPSTHGNFISRSVRAPHLSLPMAALSLSTHERPLVKATISCTNLPPDFQGPRSISATALIDSGADVTVVAETEWPSSWPAEASQSIMGVGGATPSRRSTNEVQAVVINRDGSLEKPALLTPLVARVPGTLLGRDFLRQIGIPQYPLNTFKGYVTNVTACDNDADLASQTACLIKALNTTLPWDPQELDILGSQMIKNGTTRTCVTFGSVCYKENNRSRVCHNFDGNFNGTGGAEAELRDFIEKWKSDDLLIRPYVNQSWTMVSPINVESFSISRRYCGFTSNETHYYRGDLSNWCGSKRGKWSAGYRNGTKCSSNTTGCGGNCTTEWNYYAYGFTFGKQPEVLWNNGTAKALPPGIFLICGDRAWQGIPRNALGGPCYLGQLTMLSPNFTTWITYGPNITGHRRSRRSLSRLSPDCGDELQLWSVTARIFASFFAPGIAAAQALKEIERLACWSVKQANLTSLILNAMLEDTSSIRHAVLQNRAAIDFLLLAQGHGCQDVEGMCCFNLSDHSESIHKALQAMKEHTEKIRLEDDPIGDWFTRTFGDLGRLLAKGVKTLLFALLVIACLLAIIPCIIKCFQDCLLRTMNQFMDERIKYHRIREQL", "length": 1138, "header": "tr|A0A8V0YNX6-1|A0A8V0YNX6_CHICK Isoform 1 of Gag polyprotein OS=Gallus gallus OX=9031 GN=LOC112532140 PE=4 SV=1 CANONICAL=A0A8V0YNX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6/entry", "sequence": { "sequence": "MDQVIKVLVQFCKDYCGKSTPSRKEIATVLSLLNELGELDSPRHILDSNRWDLLTSALCQRAMASQKATELKTWGLMLGALKAARAEHKLGAVMSGEGAPGSGSLEFCRTGAPTGAPTGAPTGAQTTANKTATEREEDCEKEDCEKDNEESQRLGGGATTPTAPPNSIALSPPPPYPKQPLYPSLATTSEQGAGPSPKGKGEGRLKLTDWGQIKEEVAQKGLAATYTLPVVVSEEGGPIWVPLDPKGVARMIEAVEKKGLKSPLTMNALEALTASGPVLPYDIENLMRMVLKPVQYTLWREEWHTKLKQMLIMAQGDQRNPIYGSDIQRLTGNAPGLLTPQAQVCQLRPGELIATTDAAIDAFRKLARSAEPTTPWTEIAQGPTEPFQEFADRLIKAVEGSDLPRAVHGPVILDCLYQKSSEGVQGILRAAPGRLQTPGEAIKYVLDKQKACPSVAGEVAAAVAGVMMACREADHRSADRQLGPCFKCGQLGHIRAQCRMGTGGGVTCQQCGRKGHTAPQCRARRPPRQGNNNGRPSTHGNFISRSVRAPHLSLPMAALSLSTHERPLVKATISCTNLPPDFQGPRSISATALIDSGADVTVVAETEWPSSWPAEASQSIMGVGGATPSRRSTNEVQAVVINRDGSLEKPALLTPLVARVPGTLLGRDFLRQIGIPQYPLNTFKGYVTNVTACDNDADLASQTACLIKALNTTLPWDPQELDILGSQMIKNGTTRTCVTFGSVCYKENNRSRVCHNFDGNFNGTGGAEAELRDFIEKWKSDDLLIRPYVNQSWTMVSPINVESFSISRRYCGFTSNETHYYRGDLSNWCGSKRGKWSAGYRNGTKCSSNTTGCGGNCTTEWNYYAYGFTFGKQPEVLWNNGTAKALPPGIFLICGDRAWQGIPRNALGGPCYLGQLTMLSPNFTTWITYGPNITGHRRSRRSLSRLSPDCGDELQLWSVTARIFASFFAPGIAAAQALKEIERLACWSVKQANLTSLILNAMLEDTSSIRHAVLQNRAAIDFLLLAQGHGCQDVEGMCCFNLSDHSESIHKALQAMKEHTEKIRLEDDPIGDWFTRTFGDLGRLLAKGVKTLLFALLVIACLLAIIPCIIKCFQDCLLRTMNQFMDERIKYHRIREQL", "length": 1138, "header": "tr|A0A8V0YNX6-1|A0A8V0YNX6_CHICK Isoform 1 of Gag polyprotein OS=Gallus gallus OX=9031 GN=LOC112532140 PE=4 SV=1 CANONICAL=A0A8V0YNX6-1" }, "locus": { "chromosome": "Z", "start_pos": 32669956, "end_pos": 32666543, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034724.1", "url": "https://www.ensembl.org/id/ENSGALT00010034724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020366.1", "url": "https://www.ensembl.org/id/ENSGALP00010020366.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 384, "start_aa": "Thr", "end_pos": 384, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr384", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 627, "start_aa": "Thr", "end_pos": 627, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr627", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": 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"aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1041, "end_pos": 1043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 816, "end_pos": 818, "annotation": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YNY7-1", "uniprot_ac": "A0A8V0YNY7", "uniprot_id": "A0A8V0YNY7_CHICK", "mass": { "chemical_mass": 34140.0, "monoisotopic_mass": 34140.0 }, "refseq": {}, "gene_names": [ { "name": "SPARC", "type": "recommended", "evidence": [ { "id": "A0A8V0YNY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ] } ], "protein_names": [ { "name": "SPARC", "type": "recommended", "evidence": [ { "id": "A0A8V0YNY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7/entry#names_and_taxonomy" } ] }, { "name": "Osteonectin", "type": "synonym", "evidence": [ { "id": "A0A8V0YNY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7/entry#names_and_taxonomy" } ] }, { "name": "Secreted protein acidic and rich in cysteine", "type": "synonym", "evidence": [ { "id": "A0A8V0YNY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. 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"https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPARC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7", "locus": { "chromosome": "13", "start_pos": 12530597, "end_pos": 12522257, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014390", "url": "https://www.ensembl.org/id/ENSGALG00010014390" } ] } } ], "crossref": [ { "id": "A0A8V0YNY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "386571", "url": "https://www.ncbi.nlm.nih.gov/gene/386571", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:386571", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386571", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTDELMA", "url": "https://omabrowser.org/oma/group/CTDELMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNY1", "url": "https://www.orthodb.org/?gene=A0A8V0YNY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNY7", "url": "https://www.orthodb.org/?gene=A0A8V0YNY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR2", "url": "https://www.orthodb.org/?gene=A0A8V0YQR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVS5", "url": "https://www.orthodb.org/?gene=A0A8V0YVS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YNY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEGPVGANPVQVEVGDESLFPRSDITPWLVPDPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 299, "header": "tr|A0A8V0YNY7-1|A0A8V0YNY7_CHICK Isoform 1 of SPARC OS=Gallus gallus OX=9031 GN=SPARC PE=3 SV=1 CANONICAL=A0A8V0YNY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY1/entry", "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEEPTEDVEEIVAENPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 282, "header": "tr|A0A8V0YNY1-1|A0A8V0YNY7_CHICK Computationally mapped isoform of SPARC OS=Gallus gallus OX=9031 GN=SPARC PE=3 SV=1 CANONICAL=A0A8V0YNY7-1" }, "locus": { "chromosome": "13", "start_pos": 12529431, "end_pos": 12526526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034728.1", "url": "https://www.ensembl.org/id/ENSGALT00010034728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020369.1", "url": "https://www.ensembl.org/id/ENSGALP00010020369.1" } ] } }, { "isoform_ac": "A0A8V0YNY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7/entry", "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEGPVGANPVQVEVGDESLFPRSDITPWLVPDPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 299, "header": "tr|A0A8V0YNY7-1|A0A8V0YNY7_CHICK Isoform 1 of SPARC OS=Gallus gallus OX=9031 GN=SPARC PE=3 SV=1 CANONICAL=A0A8V0YNY7-1" }, "locus": { "chromosome": "13", "start_pos": 12529431, "end_pos": 12526526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034681.1", "url": "https://www.ensembl.org/id/ENSGALT00010034681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020352.1", "url": "https://www.ensembl.org/id/ENSGALP00010020352.1" } ] } }, { "isoform_ac": "A0A8V0YQR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR2/entry", "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEVVEVGEFEEPTEDVEEIVAENPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 290, "header": "tr|A0A8V0YQR2-1|A0A8V0YQR2_CHICK Computationally mapped isoform of SPARC OS=Gallus gallus OX=9031 GN=SPARC PE=3 SV=1 CANONICAL=A0A8V0YNY7-1" }, "locus": { "chromosome": "13", "start_pos": 12529431, "end_pos": 12526526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034741.1", "url": "https://www.ensembl.org/id/ENSGALT00010034741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020373.1", "url": "https://www.ensembl.org/id/ENSGALP00010020373.1" } ] } }, { "isoform_ac": "A0A8V0YVS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS5/entry", "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEGPVGANPVQVEVGEFEEPTEDVEEIVAENPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 298, "header": "tr|A0A8V0YVS5-1|A0A8V0YNY7_CHICK Computationally mapped isoform of SPARC OS=Gallus gallus OX=9031 GN=SPARC PE=3 SV=1 CANONICAL=A0A8V0YNY7-1" }, "locus": { "chromosome": "13", "start_pos": 12529431, "end_pos": 12526526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034707.1", "url": "https://www.ensembl.org/id/ENSGALT00010034707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020361.1", "url": "https://www.ensembl.org/id/ENSGALP00010020361.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:386571", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:386571", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R6P1-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAWIFFLLCLAGKALAAPQQEALPDETEVVEETVAEVPVGANPVQVEVGEFDDGAEEAEEEVVAENPCQNHHCKHGKVCELDENNSPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDENNNLLTEKQKLRVKKIHENEKRLEGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFQTCDLDNDKYIALDEWAGCFGIKEQDIDKDLVI", "length": 299 }, "evidence": [ { "id": "A0A8V0YNY7", "url": "https://omabrowser.org/oma/group/A0A8V0YNY7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P07214-1", "protein_name": "SPARC", "gene_name": "Sparc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQTEVAEEIVEEETVVEETGVPVGANPVQVEMGEFEDGAEETVEEVVADNPCQNHHCKHGKVCELDESNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSELTEFPLRMRDWLKNVLVTLYERDEGNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALEEWAGCFGIKEQDINKDLVI", "length": 302 }, "evidence": [ { "id": "A0A8V0YNY7", "url": "https://omabrowser.org/oma/group/A0A8V0YNY7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09486-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI", "length": 303 }, "evidence": [ { "id": "A0A8V0YNY7", "url": "https://omabrowser.org/oma/group/A0A8V0YNY7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13213-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI", "length": 303 }, "evidence": [ { "id": "A0A8V0YNY7", "url": "https://omabrowser.org/oma/group/A0A8V0YNY7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P16975-1", "protein_name": "SPARC", "gene_name": "Sparc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQTEAAEEMVAEETVVEETGLPVGANPVQVEMGEFEEGAEETVEEVVAENPCQNHHCKHGKVCELDESNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSELTEFPLRMRDWLKNVLVTLYERDEGNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALEEWAGCFGIKEQDINKDLVI", "length": 301 }, "evidence": [ { "id": "A0A8V0YNY7", "url": "https://omabrowser.org/oma/group/A0A8V0YNY7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "semicircular canal morphogenesis", "id": "GO:0048752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048752", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY7" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 147, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YP06-1", "uniprot_ac": "A0A8V0YP06", "uniprot_id": "A0A8V0YP06_CHICK", "mass": { "chemical_mass": 23387.0, "monoisotopic_mass": 23387.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "H15 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YP06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP06/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP06#function" }, { "database": "UniProtKB", "id": "ARBA00002809", "url": "https://www.uniprot.org/uniprotkb/ARBA00002809#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP06", "locus": {} } ], "crossref": [ { "id": "A0A8V0YP06", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP06", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"url": "https://www.ensembl.org/id/ENSGALG00010014519" } ] } } ], "crossref": [ { "id": "A0A8V0YP21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15123", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15123", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP21", "url": 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"MGKEMSQVYLHPSNQTLCAATNGTELKSILDNETTNEKWTEDSFPGLEILCTIYVTYAVIISVGLLGNAILIKVFFKIKSMQTVPNIFITSLAFGDLLLLLTCVPVDATRYIVDTWIFGRIGCKLLSFIQLTSVGVSVFTLTVLSADRYRAIVKPLELQTSDALLKTCCKAGCVWIVSMVFAIPEAVFSDLYSFSNPEKNVTFEACAPYPVSEKILQEVHSLVCFLVFYIVPLAVISVYYFLIARTLYKSTFNMPAEEHGHARKQIESRKRVAKTVLVLVALFAFCWLPNHILYLYRSFTYHTSVDASTFHLIVTIFSRALAFSNSCVNPFALYWLSKSFRQHFKKQVSCCKAKLCTKPPSAPHSNSPPRALSVTGSTHGSEISVTLLTDYSITKEEESV", "length": 400, "header": "tr|A0A8V0YP21-1|A0A8V0YP21_CHICK Isoform 1 of Bombesin receptor subtype-3 OS=Gallus gallus OX=9031 GN=BRS3 PE=3 SV=1 CANONICAL=A0A8V0YP21-1" }, "locus": { "chromosome": "4", "start_pos": 4282720, "end_pos": 4278413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034861.1", "url": "https://www.ensembl.org/id/ENSGALT00010034861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020416.1", "url": "https://www.ensembl.org/id/ENSGALP00010020416.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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"A0A8V0YP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP21" } ], "pmid": "" }, { "name": "bombesin receptor activity", "id": "GO:0004946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004946", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP21" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 333, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"crossref": [ { "id": "A0A8V0YP32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP32", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP32", "url": "https://www.orthodb.org/?gene=A0A8V0YP32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAESGTGAAERRELSPRSQQQLQERTPPPPAAPPPAPQAAPRRSPQLRVLLTPLPAPGRRLPQKRLLGAYDGAAGGDGKRRRAEPSSPERADSGSDGDGDGDSDSDSDGTEAGQDGSPQLSAYERKRLKNISENAKFFAALKLHESAARLHEIAAKGTSQVARRAKPRKAESGTVQRRSMRLQRIQPPEVPQVEAPAQEEEYPQVPAGPLPMAADGQEEKSETALLGTWLQLSEMKHNDTEKRTWDMKRYQAALSSMLLREDGVRKVVSSRVCSVAIHPSESTVLVAAGDKNGHVGLWDVSCTAEGGAHVFTPHNSSVNCMHFSPSQPAQLLSLSHDSLRCGDVSRAVFDEICRSEDGLSSFDFLEDSACTALVGLWDGTVAVVDRRTPGTSPELLADIGFKVTRTVAVHPVDRQYFLAAGSVDVRVFDVRWLRRSGSSAVSALRGHTKSVASAYFSPVSGRRVVTVCADDRLRVYDTSSLSATAALLSTVRHNNNTGRWLTRFRAVWDPKQEQCFVVGSMARPRQVEVFQDTGVLLHAFCSPECLGSVCSINAFHPTRNVLVGGNSSGRLHVFMG", "length": 577, "header": "tr|A0A8V0YP32-1|A0A8V0YP32_CHICK Isoform 1 of WD repeat-containing protein 76 OS=Gallus gallus OX=9031 GN=WDR76 PE=3 SV=1 CANONICAL=A0A8V0YP32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32/entry", "sequence": { "sequence": "MAAESGTGAAERRELSPRSQQQLQERTPPPPAAPPPAPQAAPRRSPQLRVLLTPLPAPGRRLPQKRLLGAYDGAAGGDGKRRRAEPSSPERADSGSDGDGDGDSDSDSDGTEAGQDGSPQLSAYERKRLKNISENAKFFAALKLHESAARLHEIAAKGTSQVARRAKPRKAESGTVQRRSMRLQRIQPPEVPQVEAPAQEEEYPQVPAGPLPMAADGQEEKSETALLGTWLQLSEMKHNDTEKRTWDMKRYQAALSSMLLREDGVRKVVSSRVCSVAIHPSESTVLVAAGDKNGHVGLWDVSCTAEGGAHVFTPHNSSVNCMHFSPSQPAQLLSLSHDSLRCGDVSRAVFDEICRSEDGLSSFDFLEDSACTALVGLWDGTVAVVDRRTPGTSPELLADIGFKVTRTVAVHPVDRQYFLAAGSVDVRVFDVRWLRRSGSSAVSALRGHTKSVASAYFSPVSGRRVVTVCADDRLRVYDTSSLSATAALLSTVRHNNNTGRWLTRFRAVWDPKQEQCFVVGSMARPRQVEVFQDTGVLLHAFCSPECLGSVCSINAFHPTRNVLVGGNSSGRLHVFMG", "length": 577, "header": "tr|A0A8V0YP32-1|A0A8V0YP32_CHICK Isoform 1 of WD repeat-containing protein 76 OS=Gallus gallus OX=9031 GN=WDR76 PE=3 SV=1 CANONICAL=A0A8V0YP32-1" }, "locus": { "chromosome": "10", "start_pos": 19933820, "end_pos": 19927620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039440.1", "url": "https://www.ensembl.org/id/ENSGALT00010039440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022755.1", "url": "https://www.ensembl.org/id/ENSGALP00010022755.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA damage checkpoint", "id": "GO:2000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YP51-1", "uniprot_ac": "A0A8V0YP51", "uniprot_id": "A0A8V0YP51_CHICK", "mass": { "chemical_mass": 115753.0, "monoisotopic_mass": 115753.0 }, "refseq": { "ac": "XP_046761850", "name": "NAD(P) transhydrogenase, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761850" }, "gene_names": [ { "name": "NNT", "type": "recommended", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ] }, { "name": "NNT", "type": "synonym", "evidence": [ { "id": "XP_046761850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761850" } ] } ], "protein_names": [ { "name": "NAD(P) transhydrogenase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51/entry#names_and_taxonomy" } ] }, { "name": "7.1.1.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51/entry#names_and_taxonomy" } ] }, { "name": "NAD(P) transhydrogenase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046761850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761850" } ] }, { "name": "Nicotinamide nucleotide transhydrogenase", "type": "synonym", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046761850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761850" } ] }, { "annotation": "The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51#function" }, { "database": "UniProtKB", "id": "ARBA00054910", "url": "https://www.uniprot.org/uniprotkb/ARBA00054910#function" }, { "database": "UniProtKB", "id": "A0A8V0YW04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW04#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NNT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51", "locus": { "chromosome": "Z", "start_pos": 14324189, "end_pos": 14280728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014579", "url": "https://www.ensembl.org/id/ENSGALG00010014579" } ] } } ], "crossref": [ { "id": "A0A8V0YP51", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP51", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427196", "url": "https://www.ncbi.nlm.nih.gov/gene/427196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EQCREVD", "url": "https://omabrowser.org/oma/group/EQCREVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP51", "url": "https://www.orthodb.org/?gene=A0A8V0YP51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW04", "url": "https://www.orthodb.org/?gene=A0A8V0YW04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10160:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10160:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01262", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-71403", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71403", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046761850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "47992", "url": "https://www.rhea-db.org/rhea/47992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTSAIPYVARSQLGGWGDMASLLRVAVSGCSVPVLGAVLPPKVHSTKMPCLRMFGTHQVLWSQAAPKPGIPYKQLTVGVPKEIFENEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYREVGAKIQGTKEVLASDVIVKVRAPMHNPALGVHEADLFKTAPTLISFIYPAQNPDLLKKLAEKRTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKVLIIGGGVAGLASAGAAKSMGAVVRGFDTRAAALEQFKSLGAEPLEVDIKESGEGQGGYAKEMSKEFIEAEMKLFAKQCQDVDIIITTALIPGKKAPVLFKKDMIESMKEGSVVVDLAAEAGGNIETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNIIKLLKAISPDKENFYFDPKDQFDYGTLDHVIRGTVVMKDGKVIFPAPPPNNIPQGAPVKPKTVAELEAEKAATITPFRKTMTSASVYTTGLASMLGLGIVSPNTAFTQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGTYLPENAPQSLAVLSAFISSINIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPGGVFVGGYAAALSGGYSIEQMMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPSPELLAQMSGAMALGGTIGLTIAKRIQITDLPQLVAAFHSLVGLAAVLTCVAEYMIEYPHFATDPAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILNSAPLLLPGRHALNAGLLAASFGGMIPYMIDPSYTTGITCLGSVSALSAIMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEITGTHTEINVDNAIEMIKEANSIIITPGYGLCAAKAQYPIADLVKMLREQGKNVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINEDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKARESYQS", "length": 1105, "header": "tr|A0A8V0YP51-1|A0A8V0YP51_CHICK Isoform 1 of NAD(P) transhydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=NNT PE=1 SV=1 CANONICAL=A0A8V0YP51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51/entry", "sequence": { "sequence": "MPTSAIPYVARSQLGGWGDMASLLRVAVSGCSVPVLGAVLPPKVHSTKMPCLRMFGTHQVLWSQAAPKPGIPYKQLTVGVPKEIFENEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYREVGAKIQGTKEVLASDVIVKVRAPMHNPALGVHEADLFKTAPTLISFIYPAQNPDLLKKLAEKRTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKVLIIGGGVAGLASAGAAKSMGAVVRGFDTRAAALEQFKSLGAEPLEVDIKESGEGQGGYAKEMSKEFIEAEMKLFAKQCQDVDIIITTALIPGKKAPVLFKKDMIESMKEGSVVVDLAAEAGGNIETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNIIKLLKAISPDKENFYFDPKDQFDYGTLDHVIRGTVVMKDGKVIFPAPPPNNIPQGAPVKPKTVAELEAEKAATITPFRKTMTSASVYTTGLASMLGLGIVSPNTAFTQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGTYLPENAPQSLAVLSAFISSINIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPGGVFVGGYAAALSGGYSIEQMMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPSPELLAQMSGAMALGGTIGLTIAKRIQITDLPQLVAAFHSLVGLAAVLTCVAEYMIEYPHFATDPAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILNSAPLLLPGRHALNAGLLAASFGGMIPYMIDPSYTTGITCLGSVSALSAIMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEITGTHTEINVDNAIEMIKEANSIIITPGYGLCAAKAQYPIADLVKMLREQGKNVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINEDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKARESYQS", "length": 1105, "header": "tr|A0A8V0YP51-1|A0A8V0YP51_CHICK Isoform 1 of NAD(P) transhydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=NNT PE=1 SV=1 CANONICAL=A0A8V0YP51-1" }, "locus": { "chromosome": "Z", "start_pos": 14322590, "end_pos": 14281406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035002.1", "url": "https://www.ensembl.org/id/ENSGALT00010035002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020456.1", "url": "https://www.ensembl.org/id/ENSGALP00010020456.1" } ] } }, { "isoform_ac": "A0A8V0YW04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW04/entry", "sequence": { "sequence": "MFANVWNPPGALVPGSSEARTGIPYKQLTVGVPKEIFENEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYREVGAKIQGTKEVLASDVIVKVRAPMHNPALGVHEADLFKTAPTLISFIYPAQNPDLLKKLAEKRTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKVLIIGGGVAGLASAGAAKSMGAVVRGFDTRAAALEQFKSLGAEPLEVDIKESGEGQGGYAKEMSKEFIEAEMKLFAKQCQDVDIIITTALIPGKKAPVLFKKDMIESMKEGSVVVDLAAEAGGNIETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNIIKLLKAISPDKENFYFDPKDQFDYGTLDHVIRGTVVMKDGKVIFPAPPPNNIPQGAPVKPKTVAELEAEKAATITPFRKTMTSASVYTTGLASMLGLGIVSPNTAFTQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGTYLPENAPQSLAVLSAFISSINIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPGGVFVGGYAAALSGGYSIEQMMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPSPELLAQMSGAMALGGTIGLTIAKRIQITDLPQLVAAFHSLVGLAAVLTCVAEYMIEYPHFATDPAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILNSAPLLLPGRHALNAGLLAASFGGMIPYMIDPSYTTGITCLGSVSALSAIMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEITGTHTEINVDNAIEMIKEANSIIITPGYGLCAAKAQYPIADLVKMLREQGKNVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINEDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKARESYQS", "length": 1057, "header": "tr|A0A8V0YW04-1|A0A8V0YP51_CHICK Computationally mapped isoform of NAD(P) transhydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=NNT PE=1 SV=1 CANONICAL=A0A8V0YP51-1" }, "locus": { "chromosome": "Z", "start_pos": 14322590, "end_pos": 14281807, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035008.1", "url": "https://www.ensembl.org/id/ENSGALT00010035008.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020458.1", "url": "https://www.ensembl.org/id/ENSGALP00010020458.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 539, "start_aa": "Thr", "end_pos": 539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr539", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-71403", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71403", "resource": "Reactome", "description": "Citric acid cycle (TCA cycle)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1STM2-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTQEVASEILTYLQGNWAFGKLGAPRNMANLLKTVVTGCSCPFRSSWGSCKVLPGKKDFLRTFHTHQALWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGVKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSATLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGVTHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGEVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGLAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIVEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGILKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1113 }, "evidence": [ { "id": "A0A8V0YP51", "url": "https://omabrowser.org/oma/group/A0A8V0YP51/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P11024-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANLLKTVVTGCSCPFLSNLGSCKVLPGKKNFLRTFHTHRILWCSAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQALVKQGFNVVVESGAGEASKFSDDHYRAAGAQIQGAKEVLASDLVVKVRAPMLNPTLGVHEADLLKTSGTLISFIYPAQNPDLLNKLSKRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPILFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYVHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFEVKDDFDFGTMGHVIRGTVVMKDGQVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMTSASVYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLVLMGGHLYPSTTSQGLAALATFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLASLYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHLLNAGLLAGSVGGIIPFMMDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086 }, "evidence": [ { "id": "A0A8V0YP51", "url": "https://omabrowser.org/oma/group/A0A8V0YP51/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q13423-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "NNT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVLASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMGHVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086 }, "evidence": [ { "id": "A0A8V0YP51", "url": "https://omabrowser.org/oma/group/A0A8V0YP51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55F30-1", "protein_name": "NAD(P) transhydrogenase, mitochondrial", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLLSLITKKVSPNQIGTILKTKSSSSSSLLNNIRYSTLNNSNKLIHPISTSTRFNCNFNESNKNVLNKNNFEPSNKVISIKRNVTNRLFYSTLKDQTGSVLPTTPNQGITSIDMALELTKDAKGIPFEQLTIGIPTEVYQNEKRVSMTPENVGVLVKKGYKVLVEEGAGKGAKFSDAKYIEAGAKITTAANLFKKTDILLKVRGPQFNTNLGKHEVEMMKEGATVISFLSPAQNAETLKLLSQKKANAIAVDCIPRISRAQVFDGLSSMANIAGYKAVMEASNYFGRFFGGAITAAGRVQPAKVLVIGAGVAGLSAIGTAKNIGAIVRAFDTRSVTKEQVESLGGEFLEVKIKESGEGSGGYAKHMSKEYIEAEMALFERQCKEVDIVITTALIPGVPAPKLITKQMVDQMKPGSVIVDLAAETGGNCELTKPGEAYNYNGVSIIGFTDLPSKMATQSSTLYSNNITKFLLSLGNDKDGFKLDFTDEVHRGSTVTYNGTLIWPAPKKPVPVTPPSPSTPVSNKEKVESNLVKEETSLFNKTLKSALGATAAMCGAVAMSMGLPADFMVNLTTFSLAALIGYKVVWGVTPALHSPLMSITNAISGIVAVAGLHLMGGGYIPSTGGQLLASAAVFMASINIAGGFTITKRMLDMFKLPTDKPTYEYLYGIPSLGFLAAYLSTVGSGGPALTQLAYLASSIMCILSISGLSSAKSSRLGNILGMGGIAIGLGATVASLGVSSALLAQMAGVGLVGGGIGYLFSKRVNFTELPQLTAAFHSFVGMAAVLASGASLLADYSNFAALDTIHKSSVYLGALIGGITFTGSVVAYAKLQGHIGKWKVPSKPYHVPNRHLVNTGLALANVATFATFLSTTNPTLGLACLGATTILSFIQGHLLTAAINGPDMPVVVTVLNSYSGWALVAEGFMLDSSLLNIVGAIVGSSGAILSYIMCKAMNRNLMSVILGGVGTSSMGKGEAMKITGTHTEINVDQASEMITNSKNILIVPGYGMVVSKSQYPVAEMVKTLIEKGHNVKFGIHPVAGRLPGHLNICLSEAKVPYDIVFEMEEINPEMKDIDLAIVIGANDTVNSASVEDPNSIIAGMPVIEVWKAKHCIVMKRSLTNAGYADIQNPVFYKPNTSMLLGDATNTCKELANKIDKHYNSSH", "length": 1163 }, "evidence": [ { "id": "A0A8V0YP51", "url": "https://omabrowser.org/oma/group/A0A8V0YP51/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" }, { "name": "proton-translocating NAD(P)+ transhydrogenase activity", "id": "GO:0008750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "reactive oxygen species metabolic process", "id": "GO:0072593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" }, { "name": "NADPH regeneration", "id": "GO:0006740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1028, "end_pos": 1030, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47992", "name": "", "equation": "NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP51-1" ], "evidence": [ { "id": "47992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47992" } ] }, { "id": "R-GGA-450971", "name": "NNT dimer transfers proton from NADPH to NAD+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrion", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP51-1" ], "evidence": [ { "id": "R-GGA-450971", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450971" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YP51", "gene_name": "NNT", "activity": [ { "ec_number": "7.1.1.1", "activity": "NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out).", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ] }, { "ec_number": "7.1.1.1", "activity": "", "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" }, { "id": "SM01003", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 218, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP51" }, { "id": "SM01002", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 391, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { 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"XP_426702", "name": "claudin-16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426702" }, "gene_names": [ { "name": "CLDN16", "type": "recommended", "evidence": [ { "id": "A0A8V0YPC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ] }, { "name": "CLDN16", "type": "synonym", "evidence": [ { "id": "XP_426702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426702" } ] } ], "protein_names": [ { "name": "Claudin", "type": "recommended", "evidence": [ { "id": "A0A8V0YPC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2/entry#names_and_taxonomy" } ] }, { "name": "claudin-16", "type": "synonym", "evidence": [ { "id": "XP_426702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426702" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426702" } ] }, { "annotation": "Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2#function" }, { "database": "UniProtKB", "id": "RU060637", "url": "https://www.uniprot.org/uniprotkb/RU060637#function" } ] }, { "annotation": "Forms paracellular channels: coassembles with CLDN19 into tight junction strands with cation-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability. Involved in the maintenance of ion gradients along the nephron. In the thick ascending limb (TAL) of Henle's loop, facilitates sodium paracellular permeability from the interstitial compartment to the lumen, contributing to the lumen-positive transepithelial potential that drives paracellular magnesium and calcium reabsorption.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2#function" }, { "database": "UniProtKB", "id": "ARBA00058984", "url": "https://www.uniprot.org/uniprotkb/ARBA00058984#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLDN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2", "locus": { "chromosome": "9", "start_pos": 13619823, "end_pos": 13627624, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014643", "url": "https://www.ensembl.org/id/ENSGALG00010014643" } ] } } ], "crossref": [ { "id": "A0A8V0YPC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "429147", "url": "https://www.ncbi.nlm.nih.gov/gene/429147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429147", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLHCVKF", "url": "https://omabrowser.org/oma/group/GLHCVKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPC2", "url": "https://www.orthodb.org/?gene=A0A8V0YPC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLDVPTPAGMRFFLQYAGCFFAFFSTGFLIASTWTDCWMVNADDSLEVSTKCRGLWWECVTNVFDGIQTCDEYDSIFAEHPVKLVLTRAMMITADILAGFGFLFLVLGLDCVKFLPDEPLIKLRICLVSGVTLLIAGLPGITGSVWYAIDVYVERSSLVFHNIFLGIQYKFGWSCWLGMAGSLGCFLSGSLLTCCMYLFRETSSGRLHSAYSLRKGYSSAGTIVTNVHLPSSQTATAKMYAVDTRV", "length": 247, "header": "tr|A0A8V0YPC2-1|A0A8V0YPC2_CHICK Isoform 1 of Claudin OS=Gallus gallus OX=9031 GN=CLDN16 PE=3 SV=1 CANONICAL=A0A8V0YPC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2/entry", "sequence": { "sequence": "MPLDVPTPAGMRFFLQYAGCFFAFFSTGFLIASTWTDCWMVNADDSLEVSTKCRGLWWECVTNVFDGIQTCDEYDSIFAEHPVKLVLTRAMMITADILAGFGFLFLVLGLDCVKFLPDEPLIKLRICLVSGVTLLIAGLPGITGSVWYAIDVYVERSSLVFHNIFLGIQYKFGWSCWLGMAGSLGCFLSGSLLTCCMYLFRETSSGRLHSAYSLRKGYSSAGTIVTNVHLPSSQTATAKMYAVDTRV", "length": 247, "header": "tr|A0A8V0YPC2-1|A0A8V0YPC2_CHICK Isoform 1 of Claudin OS=Gallus gallus OX=9031 GN=CLDN16 PE=3 SV=1 CANONICAL=A0A8V0YPC2-1" }, "locus": { "chromosome": "9", "start_pos": 13627389, "end_pos": 13621294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035130.1", "url": "https://www.ensembl.org/id/ENSGALT00010035130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020494.1", "url": "https://www.ensembl.org/id/ENSGALP00010020494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429147", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LEG0-1", "protein_name": "Claudin", "gene_name": "Cldn16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRELLQYAACFLALFSTGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSIYAEHPLKLVVTRALMITADLLAGFGFITLLLGLDCVKFLPHEPQIKVRLCFVAGTTLLIAGAPGIIGSVWYAVDVYVERSSLIIHNIFLGIQYKFGWSCWLGMSGSLGCFLAGGLLTCCFYLFKDVGPERNYPYAMRKRYSTAGASMAKSYMTARTETAKMYAVDTRV", "length": 235 }, "evidence": [ { "id": "A0A8V0YPC2", "url": "https://omabrowser.org/oma/group/A0A8V0YPC2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q91Y55-1", "protein_name": "Claudin-16", "gene_name": "Cldn16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDLLQYAACFLAIFSTGFLIVATRTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSIYAEHPLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDEPHIKVRLCFVAGTVLLIAGTPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGALLTCCLYLFKDVGPERNYPYAMRKPYSTAGVSMAKSYKAPRTETAKMYAVDTRV", "length": 235 }, "evidence": [ { "id": "A0A8V0YPC2", "url": "https://omabrowser.org/oma/group/A0A8V0YPC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q925N4-1", "protein_name": "Claudin-16", "gene_name": "Cldn16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDLLQYAACFLAIFSTGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSIYAEHPLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDDPQIKVRLCFVAGTTLLIAGTPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGALLTCCLYLFKDVGPERNYPYAMRKPYSTAGVSMAKSYKAPRTETAKMYAVDTRV", "length": 235 }, "evidence": [ { "id": "A0A8V0YPC2", "url": "https://omabrowser.org/oma/group/A0A8V0YPC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XT98-1", "protein_name": "Claudin-16", "gene_name": "CLDN16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPGLAASHVSFPDSLLAKMRDLLQYVACFFAFFSAGFLVVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHSLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDEPYIKVRISFVAGTTLLIAGAPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAILTCCLYLFKDVGPERSYPYSTRKAYSTTAVSMPRSHAIPRTQTAKMYAVDTRV", "length": 254 }, "evidence": [ { "id": "A0A8V0YPC2", "url": "https://omabrowser.org/oma/group/A0A8V0YPC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y5I7-1", "protein_name": "Claudin-16", "gene_name": "CLDN16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYAVDTRV", "length": 235 }, "evidence": [ { "id": "A0A8V0YPC2", "url": "https://omabrowser.org/oma/group/A0A8V0YPC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" }, { "name": "renal absorption", "id": "GO:0070293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" }, { "name": "paracellular transport", "id": "GO:0160184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC2" } ], "pmid": "" }, { 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151939.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151939" } ] }, { "annotation": "May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. 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"uniprotkb_annotation": "Lipid-binding serum glycoprotein N-terminal", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 317, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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}, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPI5-1", "uniprot_ac": "A0A8V0YPI5", "uniprot_id": "A0A8V0YPI5_CHICK", "mass": { "chemical_mass": 90678.0, "monoisotopic_mass": 90678.0 }, "refseq": { "ac": "NP_001026069", "name": "granulocyte colony-stimulating factor receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" }, "gene_names": [ { "name": "CSF3R", "type": "recommended", "evidence": [ { "id": "A0A8V0YPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ] }, { "name": "CSF3R", "type": "synonym", "evidence": [ { "id": "NP_001026069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" } ] } ], "protein_names": [ { "name": "Colony stimulating factor 3 receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0YPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5/entry#names_and_taxonomy" } ] }, { "name": "colony stimulating factor 3 receptor (granulocyte)", "type": "synonym", "evidence": [ { "id": "NP_001026069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" } ] }, { "name": "granulocyte colony-stimulating factor receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_001026069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" } ] }, { "name": "granulocyte colony-stimulating factor receptor", "type": "synonym", "evidence": [ { "id": "NP_001026069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Sep 23, 2021 this sequence version replaced NP_001026069.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSF3R", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5", "locus": { "chromosome": "23", "start_pos": 4381043, "end_pos": 4375560, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014690", "url": "https://www.ensembl.org/id/ENSGALG00010014690" } ] } } ], "crossref": [ { "id": "A0A8V0YPI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419620", "url": "https://www.ncbi.nlm.nih.gov/gene/419620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419620", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYCSIPR", "url": "https://omabrowser.org/oma/group/SYCSIPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPF5", "url": "https://www.orthodb.org/?gene=A0A8V0YPF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPI0", "url": "https://www.orthodb.org/?gene=A0A8V0YPI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPI5", "url": "https://www.orthodb.org/?gene=A0A8V0YPI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48423:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48423:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06328", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06328", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-449836", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9674555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9674555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9705462", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9705462", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRGAGSPLLLQLSLLLLLSPSGTQQSGAELDCASVAVGAPVVPMGSAVTASCTIRRERCRGLEDGQPLISWLLDSEPMAGRQRRGVGGTEVSELRVPQLNRPQAKLWCCVEWNGTKQRVGVAEIRAGYPPGKPSNLSCLLDLGDYGLTCRWQQGADGHLPTNIMLKCATSRSPAVTGCTPQNGHSQCTVPRRLLQLYRPMELWVTATNALGTAESERLRIDPMDVAKLDPPTLQSIRSMPPQTDCVTLTWTMTPRNAHMELRCELRYRAPEDPSWGVLTGIAGHAGTVQHCKFLFGTLYHFQMRCRRDLARGYWSEWSVSRNYTTHEKAPEGKLDAWWSTRTAAGRMEVQLRWKAPRRQEANGRVLGYRVALGSRRRGREPQTVCNTNDTHCDFTVPVRTGRVYLSAYNAAGESSATEVILLERKGQPLAGLRAVPAGDRSLWVHWEAAPVPVVAYVLEWQPVSSEPRHCSACWQLERNGTTTTTLIRDSIEPFQQYNISVYPLYKDAVGTPAYIAAYSKQKAPSHAPKLHLKSIGKSQAKLSWEPVAVELQNGFITHYTVFWANSTAEVSSAVVNSSLSSFTIQGLKPSTLYKVHIMASTAGGSINGTTLTLVTTMLDDTEIQFLFLTLGLVFVLLIILLICFQKNGRVKQQFWPSVPDPANSSLGTWVPAEQEPLQAPGVKEPGLATISTVTVLDKAAGKQTPTWGKEPPAEPLAPPQPYMQQHRPGTLQANSGLAAEPVQYVQVVGGSSQGPQHVAPCLYLRSSSTQPLLSDPSPEPYENLWFRGAAPSCARGSLEEPLLDFPLLRGLRVSGAEELHDFQPC", "length": 827, "header": "tr|A0A8V0YPI5-1|A0A8V0YPI5_CHICK Isoform 1 of Colony stimulating factor 3 receptor OS=Gallus gallus OX=9031 GN=CSF3R PE=3 SV=1 CANONICAL=A0A8V0YPI5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF5/entry", "sequence": { "sequence": "MGSAVTASCTIRRERCRGLEDGQPLISWLLDSEPMAGRQRRGVGGTEVSELRVPQLNRPQAKLWCCVEWNGTKQRVGVAEIRAGCKCAAMQRAHLLCSDAALQLVAGGLLWGHPIRGMLPNSSPGCSPQTPPATVTGCTPQNGHSQCTVPRRLLQLYRPMELWVTATNALGTAESERLRIDPMDVAKLDPPTLQSIRSMPPQTDCVTLTWTMTPRNAHMELRCELRYRAPEDPSWGVLTGIAGHAGTVQHCKFLFGTLYHFQMRCRRDLARGYWSEWSVSRNYTTHEKGPLKGSRAGHGTASLWRRGREPQTVCNTNDTHCDFTVPVRTGRVYLSAYNAAGESSATEVILLERKGQPLAGLRAVPAGDRSLWVHWEAAPVPVVAYVLEWQPVSSEPRHCSACWQLERNGTTTTTLIRGKLGAAGCPSPPTGLCGAVLCLHPGLTAQSLH", "length": 449, "header": "tr|A0A8V0YPF5-1|A0A8V0YPI5_CHICK Computationally mapped isoform of Colony stimulating factor 3 receptor OS=Gallus gallus OX=9031 GN=CSF3R PE=3 SV=1 CANONICAL=A0A8V0YPI5-1" }, "locus": { "chromosome": "23", "start_pos": 4379099, "end_pos": 4376515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035277.1", "url": "https://www.ensembl.org/id/ENSGALT00010035277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020547.1", "url": "https://www.ensembl.org/id/ENSGALP00010020547.1" } ] } }, { "isoform_ac": "A0A8V0YPI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI0/entry", "sequence": { "sequence": "MARRGAGSPLLLQLSLLLLLSPSGTQQSGAELDCASVAVGAPVVPMGSAVTASCTIRRERCRGLEDGQPLISWLLDSEPMAGRQRRGVGGTEVSELRVPQLNRPQAKLWCCVEWNGTKQRVGVAEIRAGYPPGKPSNLSCLLDLGDYGLTCRWQQGADGHLPTNIMLKCATSRSPAVTGCTPQNGHSQCTVPRRLLQLYRPMELWVTATNALGTAESERLRIDPMDVAKLDPPTLQSIRSMPPQTDCVTLTWTMTPRNAHMELRCELRYRAPEDPSWGVLTGIAGHAGTVQHCKFLFGTLYHFQMRCRRDLARGYWSEWSVSRNYTTHEKAPEGKLDAWWSTRTAAGRMEVQLRWKAPRRQEANGRVLGYRVALGSRRRGREPQTVCNTNDTHCDFTVPVRTGRVYLSAYNAAGESSATEVILLERKGQPLAGLRAVPAGDRSLWVHWEAAPVPVVAYVLEWQPVSSEPRHCSACWQLERNGTTTTTLIRDSIEPFQQYNISVYPLYKDAVGTPAYIAAYSKQKGAVVNSSLSSFTIQGLKPSTLYKVHIMASTAGGSINGTTLTLVTTMLDDTEIQFLFLTLGLVFVLLIILLICFQKNGRVKQQFWPSVPDPANSSLGTWVPAEQEPLQAPGVKEPGLATISTVTVLDKAAGKQTPTWGKEPPAEPLAPPQPYMQQHRPGTLQANSGLAAEPVQYVQVVGGSSQGPQHVAPCLYLRSSSTQPLLSDPSPEPYENLWFRGAAPSCARGSLEEPLLDFPLLRGLRVSGAEELHDFQPC", "length": 778, "header": "tr|A0A8V0YPI0-1|A0A8V0YPI5_CHICK Computationally mapped isoform of Colony stimulating factor 3 receptor OS=Gallus gallus OX=9031 GN=CSF3R PE=3 SV=1 CANONICAL=A0A8V0YPI5-1" }, "locus": { "chromosome": "23", "start_pos": 4380837, "end_pos": 4376243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035333.1", "url": "https://www.ensembl.org/id/ENSGALT00010035333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020567.1", "url": "https://www.ensembl.org/id/ENSGALP00010020567.1" } ] } }, { "isoform_ac": "A0A8V0YPI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5/entry", "sequence": { "sequence": "MARRGAGSPLLLQLSLLLLLSPSGTQQSGAELDCASVAVGAPVVPMGSAVTASCTIRRERCRGLEDGQPLISWLLDSEPMAGRQRRGVGGTEVSELRVPQLNRPQAKLWCCVEWNGTKQRVGVAEIRAGYPPGKPSNLSCLLDLGDYGLTCRWQQGADGHLPTNIMLKCATSRSPAVTGCTPQNGHSQCTVPRRLLQLYRPMELWVTATNALGTAESERLRIDPMDVAKLDPPTLQSIRSMPPQTDCVTLTWTMTPRNAHMELRCELRYRAPEDPSWGVLTGIAGHAGTVQHCKFLFGTLYHFQMRCRRDLARGYWSEWSVSRNYTTHEKAPEGKLDAWWSTRTAAGRMEVQLRWKAPRRQEANGRVLGYRVALGSRRRGREPQTVCNTNDTHCDFTVPVRTGRVYLSAYNAAGESSATEVILLERKGQPLAGLRAVPAGDRSLWVHWEAAPVPVVAYVLEWQPVSSEPRHCSACWQLERNGTTTTTLIRDSIEPFQQYNISVYPLYKDAVGTPAYIAAYSKQKAPSHAPKLHLKSIGKSQAKLSWEPVAVELQNGFITHYTVFWANSTAEVSSAVVNSSLSSFTIQGLKPSTLYKVHIMASTAGGSINGTTLTLVTTMLDDTEIQFLFLTLGLVFVLLIILLICFQKNGRVKQQFWPSVPDPANSSLGTWVPAEQEPLQAPGVKEPGLATISTVTVLDKAAGKQTPTWGKEPPAEPLAPPQPYMQQHRPGTLQANSGLAAEPVQYVQVVGGSSQGPQHVAPCLYLRSSSTQPLLSDPSPEPYENLWFRGAAPSCARGSLEEPLLDFPLLRGLRVSGAEELHDFQPC", "length": 827, "header": "tr|A0A8V0YPI5-1|A0A8V0YPI5_CHICK Isoform 1 of Colony stimulating factor 3 receptor OS=Gallus gallus OX=9031 GN=CSF3R PE=3 SV=1 CANONICAL=A0A8V0YPI5-1" }, "locus": { "chromosome": "23", "start_pos": 4380837, "end_pos": 4376243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035318.1", "url": "https://www.ensembl.org/id/ENSGALT00010035318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020560.1", "url": "https://www.ensembl.org/id/ENSGALP00010020560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419620", "resource": "KEGG Pathway" }, { "id": "R-GGA-449836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449836", "resource": "Reactome", "description": "Other interleukin signaling" }, { "id": "R-GGA-9674555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9674555", "resource": "Reactome", "description": "Signaling by CSF3 (G-CSF)" }, { "id": "R-GGA-9705462", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9705462", "resource": "Reactome", "description": "Inactivation of CSF3 (G-CSF) signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LU43-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGLGAWSLVGAALIILLLPRSLEQCGHILLSAPIVRLGDQVTASCIINRNCSHLGTDWRVVWKLEPELHPRERRQHLPNGTLQSTITLPHLNHSRVLLSCCLHWGNSLQILDQAELQAGYPPTAPYNLSCIMNLTTNSLICQWEPGPNTHLSTSFTLKSFKSQDKCQTQKDSIPDCVPEVGQSHCSIPRKHLQLYQNMSIWVQARNALGTSASPKLCLAPMDVVKLEPPTLWALEPSPAVAPPQPGCLRLRWETWRPSLYIEQKCELRHQPRLGEAGWDLVSALPARTSQYELCGLLPSTAYTLQMRCTRWRLPGHWSEWSPSLELTTAQRAPIVRLDTWWRQRQLDPETVTVQLFWKPIALEEDSGQIQGYLVSWRPSDQAGAEPTLCDTTELNCTFQLPSEAREVVLKAYNTAGTSHPTPVVFLESRGPPLGRLHTTARDPHSLWVGWEPPSPQPQGYVIEWGLSPPSPNGSPMTWRMEHNGSIAGTLLQENIRPFQLYEITVTPLYQDTKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNTQDQSFSTVLNASTHSFVLRGLEPSSLYHVQLMAASQVWAANSTSLTLMTLTLEESELHILLGLFGLLVLLICLCGAAQFCCRPSRKYSLWPSVPDPARSSLGSWVPTITAEDILQLPSLRDPGMPPITKITVLEEEEKKPGPWESNASSGPGSLSTLVQAYVLQGDPRVPSAQPQPQPGNSDQVLYVQVLGSPTGPGPGHYLRCDSTQPLLEGLSPSPKSYENLWFQTSSPGTPEPLVPHPEDDSIFEPLLDFPLLQGLRVSGAEGLGGF", "length": 841 }, "evidence": [ { "id": "A0A8V0YPI5", "url": "https://omabrowser.org/oma/group/A0A8V0YPI5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A5G2QXL6-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVAGLGAWSLAGAVLIILLLPRSLEECGYISLPAPIIRLGDPITVSCIINQNCTSLGPESQIRWKLDTELQPGGRQQHLPNGTLQSTITFPHFNYSRALLSCCLHWGNGLQILDQAELQAGYPPPPPYNLSCLLNLTTNSLKCQWEPGPDTHLSTHFTLKSFKSRGNFQTQEDSIPDCVPEDGQNHCSIPRKHLQLYQNMSIWVQAKNALGTSTSPKLCLVPMDMVKLEPPTLWALEPSPEVAPPQPGCLRLRWETWKPSLHIEQKCELRHQPQRGESSWDLVGALPSRSLQYELCGLLPSTAYTLQMRCTRWPLPGRWSDWSPRLELTTAQQPPIVRLDTWWRQRQLDPRTVDVQLFWKPMPLQEDSGQIQGYLVSWRPSDQAEADPILCNTTELNCTFQLPSEAREVVLVAYNAAGTSRPTPVVFLESRGPPLRRLRTTARDPHSLWVGWEPPSPRPRGYVIEWGLGTPSPGGNPMTWRMEHNGSIAGTLLQENIKPFQLYKITVTALYQDAKGPSQHIYAYSQEMAPSHGPELHLRHIGKTWAQLEWVPEAPELGKSPLTHYTIFWTNAQDQSFSTVLNASSHGFVLRGLEPASLYHVHLMAVSQAWTTNSTSLTLMTLALEESELHILLGLFGLLVLFFCLCGAAQLCCRPRKNPLWPSVPDPAHSSLGSWVPTITAEDTFQLPSLRDPGMPPITKITVLEEEEKKPGPWESKSGPWESNDSSGTCSHPTLVQAYVLQGDPRVPATQAQPQSSTSDQVLYVQVLGSPTSPGPGHYLRCDSTQPLLGGLTPSPKSYENLWFQTSPLGTPEPLVPNPEDDCIFEPLLDFPLLQGLRVSGAEGLGGF", "length": 848 }, "evidence": [ { "id": "A0A8V0YPI5", "url": "https://omabrowser.org/oma/group/A0A8V0YPI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6B3M3-1", "protein_name": "Colony stimulating factor 3 receptor", "gene_name": "Csf3r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGLGACNLTGVTLIVLLLPRSLEGCGQIRISPPIVHLGDPVLASCTISPNCSKLDRQPKILWRLQDEPNQPGDRQHHLPDGSQESIITLPHLNYTQAFLFCLVPWNNSFQVLDQAELRAGYPPASPSNLSCLMYLTTNSLVCQWEPGPETHLPTSFILKSFRSRTGCQYQGGTILDCMPKKRHSNCSIPRKHLLLYQNMVIWVQAENMLGSSESPKLCIDPMDVGRESLTTPPPAVKLEPPMLQALDIGHDIVSRQPGCLWLSWKPWKPSEFMEQECELRYQPQLEGANWTLVRPRKTSRWRWGMERGQAGFSVTPPTHQVSHLPSSTDRFELCSLHQAPVYTLQLRCIRSSLPGLWSSWSPGLQLRPTIKAPTIRLDTWWQKKHLDPETVRMQLFWKPTPLQKDSGQIQGYLLSWSCPDGQGRIMHLCNTTELSCTFHLPSEAQNVTLVAYNSAGTSSPTLVVFLEHEGPAVTSLHAMAQDLGSIWVDWEAPSLLPQGYLIEWGPDSHKYSNNSWRIEPNGNTTGILLEDNIHPFQLYRITVAPLYPGTVGPPVNVYTYSGEKALPHAPELYLKHVGRTWAQLEWVPETPWLGMIPLTNYTIFWTDARDHSFSVTLNISFHDFVLDHLKPASLYHVYLMATSRAGSTNSTGLTLMTMALDSSDVNIFLGILCFVLLSITCATAWFCCKQSRKTFFWPNVPDPAHSSLSAWVPTIMTEETFQLPSFWGSSVPSITKITELEEDKKPTHWDPSESSGTGSLPAVVQAYVLQGDPREISNQFQPPSSTNDQVLYGQVLGSPTSPEVVGYLRCDSTQPLLGGPTPSPKSYENIWFHSRPQETFIPQPPSQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "length": 877 }, "evidence": [ { "id": "A0A8V0YPI5", "url": "https://omabrowser.org/oma/group/A0A8V0YPI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40223-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "Csf3r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGLGACTLTGVTLIFLLLPRSLESCGHIEISPPVVRLGDPVLASCTISPNCSKLDQQAKILWRLQDEPIQPGDRQHHLPDGTQESLITLPHLNYTQAFLFCLVPWEDSVQLLDQAELHAGYPPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILKSFRSRADCQYQGDTIPDCVAKKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIGPDVVSHQPGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLVFHLPSSKDQFELCGLHQAPVYTLQMRCIRSSLPGFWSPWSPGLQLRPTMKAPTIRLDTWCQKKQLDPGTVSVQLFWKPTPLQEDSGQIQGYLLSWSSPDHQGQDIHLCNTTQLSCIFLLPSEAQNVTLVAYNKAGTSSPTTVVFLENEGPAVTGLHAMAQDLNTIWVDWEAPSLLPQGYLIEWEMSSPSYNNSYKSWMIEPNGNITGILLKDNINPFQLYRITVAPLYPGIVGPPVNVYTFAGERAPPHAPALHLKHVGTTWAQLEWVPEAPRLGMIPLTHYTIFWADAGDHSFSVTLNISLHDFVLKHLEPASLYHVYLMATSRAGSTNSTGLTLRTLDPSDLNIFLGILCLVLLSTTCVVTWLCCKRRGKTSFWSDVPDPAHSSLSSWLPTIMTEETFQLPSFWDSSVPSITKITELEEDKKPTHWDSESSGNGSLPALVQAYVLQGDPREISNQSQPPSRTGDQVLYGQVLESPTSPGVMQYIRSDSTQPLLGGPTPSPKSYENIWFHSRPQETFVPQPPNQEDDCVFGPPFDFPLFQGLQVHGVEEQGGF", "length": 837 }, "evidence": [ { "id": "A0A8V0YPI5", "url": "https://omabrowser.org/oma/group/A0A8V0YPI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99062-1", "protein_name": "Granulocyte colony-stimulating factor receptor", "gene_name": "CSF3R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGLTPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF", "length": 836 }, "evidence": [ { "id": "A0A8V0YPI5", "url": "https://omabrowser.org/oma/group/A0A8V0YPI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" }, { "name": "granulocyte colony-stimulating factor binding", "id": "GO:0051916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051916", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI5" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 330, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPJ1-1", "uniprot_ac": "A0A8V0YPJ1", "uniprot_id": "A0A8V0YPJ1_CHICK", "mass": { "chemical_mass": 246213.0, "monoisotopic_mass": 246213.0 }, "refseq": { "ac": "XP_004949159", "name": "FRAS1-related extracellular matrix protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949159" }, "gene_names": [ { "name": "FREM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ] }, { "name": "FREM1", "type": "synonym", "evidence": [ { "id": "XP_004949159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949159" } ] } ], "protein_names": [ { "name": "FRAS1-related extracellular matrix protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1/entry#names_and_taxonomy" } ] }, { "name": "FRAS1-related extracellular matrix protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949159" } ] }, { "name": "Protein QBRICK", "type": "synonym", "evidence": [ { "id": "A0A8V0YPJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949159.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949159" } ] }, { "annotation": "Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1#function" }, { "database": "UniProtKB", "id": "ARBA00058451", "url": "https://www.uniprot.org/uniprotkb/ARBA00058451#function" }, { "database": "UniProtKB", "id": "A0A8V0YVY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVY5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FREM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1", "locus": { "chromosome": "Z", "start_pos": 32157853, "end_pos": 32216818, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016463", "url": "https://www.ensembl.org/id/ENSGALG00010016463" } ] } } ], "crossref": [ { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427355", "url": "https://www.ncbi.nlm.nih.gov/gene/427355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427355", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DIGPHLQ", "url": "https://omabrowser.org/oma/group/DIGPHLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YPJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVY5", "url": "https://www.orthodb.org/?gene=A0A8V0YVY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPFEKTWLLLLLPVLLRVVCSSFVSVNLGIKVMKGQSVFLSEDDLKFSIPREKDVCKVEVVRNEPITQRVGKLTPQVFDCHFHLNEVKYTHNGCPILDADTVMLRLYRFTENETFVETFTLHVQLLEPDCNIIKMRSRALEVAEYYGLSRAIDKNSLTFDYSRKMNLECTISIASSETHLPAHGQLIMGDTRQEKLRGDQPQSFLLGPKHSPGQQCRNGSCVLGLRVIHNTKMSCEEFLRKGIRYQHLDPRSPDIDYIPVRLDLTDSRSKTLHKTEYAWLPVRIKSAMPNQIPKAVPMTKFILEVDQFILTPITTTTVDAEDKETPKSLLVFNITKPPLQGFITHLSDHTKPVGSFTWKDLSEMLIAYQPPNNSHTERRNYELEVEVHDFYFERSLPTIVQLSIRTADTNAPRVSWNTGLSLLEGQSRPITWQHLQVVDNDDIQNVRLVTVDGLQHGRLTVRGGKGFMFTVSDIQTGVVRYHHDDSDSTKDFVVFRIFDGLHSIRHKFPINILPKDDSPPFLISNVVIEVQEGQTILIQGSMLQASDMDSSDDYIVFNITKPPQAGEIMKKPGPNLIGYPVSSFLQRDLFNGIMYYHHLGGEVFEDSIEFVLCDSHDPPNLSEPQVMTVHIAPVDDQLPKEAPGVTRHLVVKETEIAHLTKKHLHFIDVEEQDRELTYTITTSPFFSCVHGHSDAGKLFMVDTIPKLVKDPAALALRSFTQHAVNYLKVAYMPPLQDIGPNPQHVQFVFSVSNQHGGTLYGICFNITILPVDNQAPEVLTSHLRVEEGGLSPVTEGHILVSDVDTKQEHLLLLLQRQPQHGAVELDGVPMKEGDKLSCADLRTLAVSYRHDGSETLTDEVLFVATDGIHSLEFTLQVKVLPMNDEPPVVQTGLINVLSCPEGEEVVLSSEYIYATDADSDDMKLVFVLVRQPSQGVLRRAGIAVERFSQADVISGLVTYKHTGGEIGLTLTFETLTFVVSDDEAGPDVKDCCYDRLLPPPVPPHRPLPVYDLNITVLPVDNQPPSIAIGARFVVEEGSSAALTSNHLFATDPDTPADDLEFVLVSPPQFGYIENILPSPGFEKSNVGISIASFQLKHLKALNINYVQARHMRMEPRADHFVLYVTDGLHRSAEIPFFVLINPTNDEVPEFIARNITVQEGMMKELDLSVISAVDLDVPQDHLVFGVVQQPSHGFLINGVHGNDILHYKELIQHHNHGLLVHDFSMELLQNGMKLMYMHDDSESLSDSFKIQLSDGKHKVLRTISVKVIPVNDEKPVLSKKDNIEVHMGETRIISSAVLSAEDKDTPRERIYYLFERLPESGQLQLKVGRDWVTLQTGMKCTQEELDMNLVRYVHTGAIGSKNQDLFTFYLWDGYNRSPAVDFYINIKDMEKGDIAVFIKPLKVSKGDRGYITTDVLLSLDGTDKPEELLYVITSPPQYGQIEYASYPDIPITSFSQMDVASQIVCYVHNTKAHSRQDAFRFIISNGLRTKHGTFMISLEAVDQTLPTLSRNRGLRLVEGNMVLLSPDVLQLTDSDTAKENLTFILAQLPQYGHLYYRGAVLLQYSFTQRDVDNMDVAYKHRGGDSRVDKFTFVATDRTNQGFIVNGRVQIEPVAFTIQVDHLDKMAPKIIHLRCLSDVEMLKNGNYGIYITSRSLKATDPNTEDDKIFFKILQGPRYGYLENITTGGLIHEGFSQKDLNSKIIFYVINPLWEVHSDNLEFQVTDTNGNSAIPQMLELRWSRIEMQQTEYEVCENVGTVSLKITRAGHSADSAFIAVKVNEISAVLGKDFTVTPSKLIQFDPGMSTKMWNIAITYDRLEEDDEVFEVVLNSSVNAVLGTKTKAVVKILDSKGGQCSTLHSSSQSKQDFWRRGTLFAVSSGSSSPPRPGNVHLEGISPPPSKRMREHRGDTLQDRRLAYQSRAKLRVTGNGRIVHPSSIFRNGTDVVYKYHGIVSLKIEDDTSSAKANKKAEVSVINQAQPQINAISTRKTEIPQADKAELASEASSRRQDFHSFSRACTPDLKGLMHYEESTQKLFQCDGIEWKFWSSQSKEASMKKCPSGWRHHDGSCYFLVVNQKVTWDTAAQACREQYLGSLTSVANEQHMQWLWDLGGRKPFWIGLNDQVNPGHWEWNGGEPVTYINWRRGSYRFTKRGNNCVVVQKRGKWQATDCRKAKWNSYICSRKL", "length": 2184, "header": "tr|A0A8V0YPJ1-1|A0A8V0YPJ1_CHICK Isoform 1 of FRAS1-related extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=FREM1 PE=3 SV=1 CANONICAL=A0A8V0YPJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1/entry", "sequence": { "sequence": "MKPFEKTWLLLLLPVLLRVVCSSFVSVNLGIKVMKGQSVFLSEDDLKFSIPREKDVCKVEVVRNEPITQRVGKLTPQVFDCHFHLNEVKYTHNGCPILDADTVMLRLYRFTENETFVETFTLHVQLLEPDCNIIKMRSRALEVAEYYGLSRAIDKNSLTFDYSRKMNLECTISIASSETHLPAHGQLIMGDTRQEKLRGDQPQSFLLGPKHSPGQQCRNGSCVLGLRVIHNTKMSCEEFLRKGIRYQHLDPRSPDIDYIPVRLDLTDSRSKTLHKTEYAWLPVRIKSAMPNQIPKAVPMTKFILEVDQFILTPITTTTVDAEDKETPKSLLVFNITKPPLQGFITHLSDHTKPVGSFTWKDLSEMLIAYQPPNNSHTERRNYELEVEVHDFYFERSLPTIVQLSIRTADTNAPRVSWNTGLSLLEGQSRPITWQHLQVVDNDDIQNVRLVTVDGLQHGRLTVRGGKGFMFTVSDIQTGVVRYHHDDSDSTKDFVVFRIFDGLHSIRHKFPINILPKDDSPPFLISNVVIEVQEGQTILIQGSMLQASDMDSSDDYIVFNITKPPQAGEIMKKPGPNLIGYPVSSFLQRDLFNGIMYYHHLGGEVFEDSIEFVLCDSHDPPNLSEPQVMTVHIAPVDDQLPKEAPGVTRHLVVKETEIAHLTKKHLHFIDVEEQDRELTYTITTSPFFSCVHGHSDAGKLFMVDTIPKLVKDPAALALRSFTQHAVNYLKVAYMPPLQDIGPNPQHVQFVFSVSNQHGGTLYGICFNITILPVDNQAPEVLTSHLRVEEGGLSPVTEGHILVSDVDTKQEHLLLLLQRQPQHGAVELDGVPMKEGDKLSCADLRTLAVSYRHDGSETLTDEVLFVATDGIHSLEFTLQVKVLPMNDEPPVVQTGLINVLSCPEGEEVVLSSEYIYATDADSDDMKLVFVLVRQPSQGVLRRAGIAVERFSQADVISGLVTYKHTGGEIGLTLTFETLTFVVSDDEAGPDVKDCCYDRLLPPPVPPHRPLPVYDLNITVLPVDNQPPSIAIGARFVVEEGSSAALTSNHLFATDPDTPADDLEFVLVSPPQFGYIENILPSPGFEKSNVGISIASFQLKHLKALNINYVQARHMRMEPRADHFVLYVTDGLHRSAEIPFFVLINPTNDEVPEFIARNITVQEGMMKELDLSVISAVDLDVPQDHLVFGVVQQPSHGFLINGVHGNDILHYKELIQHHNHGLLVHDFSMELLQNGMKLMYMHDDSESLSDSFKIQLSDGKHKVLRTISVKVIPVNDEKPVLSKKDNIEVHMGETRIISSAVLSAEDKDTPRERIYYLFERLPESGQLQLKVGRDWVTLQTGMKCTQEELDMNLVRYVHTGAIGSKNQDLFTFYLWDGYNRSPAVDFYINIKDMEKGDIAVFIKPLKVSKGDRGYITTDVLLSLDGTDKPEELLYVITSPPQYGQIEYASYPDIPITSFSQMDVASQIVCYVHNTKAHSRQDAFRFIISNGLRTKHGTFMISLEAVDQTLPTLSRNRGLRLVEGNMVLLSPDVLQLTDSDTAKENLTFILAQLPQYGHLYYRGAVLLQYSFTQRDVDNMDVAYKHRGGDSRVDKFTFVATDRTNQGFIVNGRVQIEPVAFTIQVDHLDKMAPKIIHLRCLSDVEMLKNGNYGIYITSRSLKATDPNTEDDKIFFKILQGPRYGYLENITTGGLIHEGFSQKDLNSKIIFYVINPLWEVHSDNLEFQVTDTNGNSAIPQMLELRWSRIEMQQTEYEVCENVGTVSLKITRAGHSADSAFIAVKVNEISAVLGKDFTVTPSKLIQFDPGMSTKMWNIAITYDRLEEDDEVFEVVLNSSVNAVLGTKTKAVVKILDSKGGQCSTLHSSSQSKQDFWRRGTLFAVSSGSSSPPRPGNVHLEGISPPPSKRMREHRGDTLQDRRLAYQSRAKLRVTGNGRIVHPSSIFRNGTDVVYKYHGIVSLKIEDDTSSAKANKKAEVSVINQAQPQINAISTRKTEIPQADKAELASEASSRRQDFHSFSRACTPDLKGLMHYEESTQKLFQCDGIEWKFWSSQSKEASMKKCPSGWRHHDGSCYFLVVNQKVTWDTAAQACREQYLGSLTSVANEQHMQWLWDLGGRKPFWIGLNDQVNPGHWEWNGGEPVTYINWRRGSYRFTKRGNNCVVVQKRGKWQATDCRKAKWNSYICSRKL", "length": 2184, "header": "tr|A0A8V0YPJ1-1|A0A8V0YPJ1_CHICK Isoform 1 of FRAS1-related extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=FREM1 PE=3 SV=1 CANONICAL=A0A8V0YPJ1-1" }, "locus": { "chromosome": "Z", "start_pos": 32216546, "end_pos": 32160199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039652.1", "url": "https://www.ensembl.org/id/ENSGALT00010039652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022911.1", "url": "https://www.ensembl.org/id/ENSGALP00010022911.1" } ] } }, { "isoform_ac": "A0A8V0YVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVY5/entry", "sequence": { "sequence": "MLRLYRFTENETFVETFTLHVQLLEPDCNIIKMRSRALEVAEYYGLSRAIDKNSLTFDYSRKMNLECTISIASSETHLPAHGQLIMGDTRQEKLRGDQPQSFLLGPKHSPGQQCRNGSCVLGLRVIHNTKMSCEEFLRKGIRYQHLDPRSPDIDYIPVRLDLTDSRSKTLHKTEYAWLPVRIKSAMPNQIPKAVPMTKFILEVDQFILTPITTTTVDAEDKETPKSLLVFNITKPPLQGFITHLSDHTKPVGSFTWKDLSEMLIAYQPPNNSHTERRNYELEVEVHDFYFERSLPTIVQLSIRTADTNAPRVSWNTGLSLLEGQSRPITWQHLQVVDNDDIQNVRLVTVDGLQHGRLTVRGGKGFMFTVSDIQTGVVRYHHDDSDSTKDFVVFRIFDGLHSIRHKFPINILPKDDSPPFLISNVVIEVQEGQTILIQGSMLQASDMDSSDDYIVFNITKPPQAGEIMKKPGPNLIGYPVSSFLQRDLFNGIMYYHHLGGEVFEDSIEFVLCDSHDPPNLSEPQVMTVHIAPVDDQLPKEAPGVTRHLVVKETEIAHLTKKHLHFIDVEEQDRELTYTITTSPFFSCVHGHSDAGKLFMVDTIPKLVKDPAALALRSFTQHAVNYLKVAYMPPLQDIGPNPQHVQFVFSVSNQHGGTLYGICFNITILPVDNQAPEVLTSHLRVEEGGLSPVTEGHILVSDVDTKQEHLLLLLQRQPQHGAVELDGVPMKEGDKLSCADLRTLAVSYRHDGSETLTDEVLFVATDGIHSLEFTLQVKVLPMNDEPPVVQTGLINVLSCPEGEEVVLSSEYIYATDADSDDMKLVFVLVRQPSQGVLRRAGIAVERFSQADVISGLVTYKHTGGEIGLTLTFETLTFVVSDDEAGPDVKDCCYDRLLPPPVPPHRPLPVYDLNITVLPVDNQPPSIAIGARFVVEEGSSAALTSNHLFATDPDTPADDLEFVLVSPPQFGYIENILPSPGFEKSNVGISIASFQLKHLKALNINYVQARHMRMEPRADHFVLYVTDGLHRSAEIPFFVLINPTNDEVPEFIARNITVQEGMMKELDLSVISAVDLDVPQDHLVFGVVQQPSHGFLINGVHGNDILHYKELIQHHNHGLLVHDFSMELLQNGMKLMYMHDDSESLSDSFKIQLSDGKHKVLRTISVKVIPVNDEKPVLSKKDNIEVHMGETRIISSAVLSAEDKDTPRERIYYLFERLPESGQLQLKVGRDWVTLQTGMKCTQEELDMNLVRYVHTGAIGSKNQDLFTFYLWDGYNRSPAVDFYINIKDMEKGDIAVFIKPLKVSKGDRGYITTDVLLSLDGTDKPEELLYVITSPPQYGQIEYASYPDIPITSFSQMDVASQIVCYVHNTKAHSRQDAFRFIISNGLRTKHGTFMISLEAVDQTLPTLSRNRGLRLVEGNMVLLSPDVLQLTDSDTAKENLTFILAQLPQYGHLYYRGAVLLQYSFTQRDVDNMDVAYKHRGGDSRVDKFTFVATDRTNQGFIVNGRVQIEPVAFTIQVDHLDKMAPKIIHLRCLSDVEMLKNGNYGIYITSRSLKATDPNTEDDKIFFKILQGPRYGYLENITTGGLIHEGFSQKDLNSKIIFYVINPLWEVHSDNLEFQVTDTNGNSAIPQMLELRWSRIEMQQTEYEVCENVGTVSLKITRAGHSADSAFIAVKVNEISAVLGKDFTVTPSKLIQFDPGMSTKMWNIAITYDRLEEDDEVFEVVLNSSVNAVLGTKTKAVVKILDSKGGQCSTLHSSSQSKQDFWRRGTLFAVSSGSSSPPRPGNVHLEGISPPPSKRMREHRGDTLQDRRLAYQSRAKLRVTGNGRIVHPSSIFRNGTDVVYKYHGIVSLKIEDDTSSAKANKKAEVSVINQAQPQINAISTRKTEIPQADKAELASEASSRRQDFHSFSRACTPDLKGLMHYEESTQKLFQCDGIEWKFWSSQSKEASMKKCPSGWRHHDGSCYFLVVNQKVTWDTAAQACREQYLGSLTSVANEQHMQWLWDLGGRKPFWIGLNDQVNPGHWEWNGGEPVTYINWRRGSYRFTKRGNNCVVVQKRGKWQATDCRKAKWNSYICSRKL", "length": 2081, "header": "tr|A0A8V0YVY5-1|A0A8V0YPJ1_CHICK Computationally mapped isoform of FRAS1-related extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=FREM1 PE=3 SV=1 CANONICAL=A0A8V0YPJ1-1" }, "locus": { "chromosome": "Z", "start_pos": 32211890, "end_pos": 32160199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039654.1", "url": "https://www.ensembl.org/id/ENSGALT00010039654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022913.1", "url": "https://www.ensembl.org/id/ENSGALP00010022913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427355", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KB00-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSPGCTGPKALLFLLLQLLMLHLDPANATFISINRGLRVMKGSSAFLSGDHLRFAIPKEKDACRVEVVMNEPITQRVGKLIPQVFDCHFLPNEVQYVHNGCPILDEDSVKLRLYRFTETETFMETFLLRVSLVEPDCNIIRLSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRVDPVKTQLPAHGKLVVVNRKSEGPRGDQPHSFFSESQLGAERKCPDGSCTLEPKQVTSLKVSCEDFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTIYKSESAWLPVFIRVGIPNQAPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITEAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNNSHPERRHYKMELEVYDLFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVADLQAGVVRYHHDDSDTTKDFVAFRIFDGQHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVSGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVMVHITPVDDQLPKEAPGISRHLIVKETEVAYITKKHLHFLDTESHGGELVYTITRPPCFSSSHRHLDAGKLFMVDSIPKPTKNPTAPGLNSFTQHAVNHMKVAYMPPMQDIGPTPRHVQFTVSVSNQHGGTLHGICFNITVLPVDNQVPEVFTNTLRVAEGGQCTISTEHILVSDVDTPLDSICLSLQEMPLHGGVELDGFPLNPRGTFSWRDLHTLKVRYQHDGSEVLQDEIFLEVTDGTNSAGFVLYIEVFPVNDEPPVLKADLIPMMHCSEGGEVTITPEYIFATDADSNDSELLFLITREPRHGVVRKAGLRVDRFSQGDVISGAVAYKHTGGEIGLESCFDTVVLVVSDGEADPLVNGCCYNGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRTLTVDEGFSAALTTHHLTATDWDTAPDDLEFILVSHPQFGYLENTLPSAGFEKRNTGISIASFQWRDMKASHINYVQSRHLREEPTADEFLVYATDGKQRSLETTFHVIINPTNDEAPDFVVQNITVYEGHMVELDSAIISATDRDVPKDPLLFNITHKPKHGLLLISATSKDAHNEIHNFSMELLQNGMKLAYAHDDSESSADNFVIQLSDGKHKILKTVSVSITPVNDETPTLSKKAEVSVTVGDTRVLSSAVLSAIDKDSPREKIHYLFERLPQNGQLQLKIGRDWVPLSAGMQCTQEDVDLNLLRYAHAGKMHSQDGDRFTFYLWDGDNRSPAFDCHIIIEDTGRGDIVIHAKPLVVANGDRGLLTPATLLAEDGADKAEELLYLITSPPQYGQVEYVYSPGVPITSFSQMDIAGQAVCYIHKSRTAVLSDSFRFTISNGLQTQQGVFEITLQGVDSALPVLTRNRRLRLVEGAMGLLSTDHLQLTDPDTPPENLTFFLVQLPRHGYLYLRGKVLQHNFTQQDVDSRVVAYQHAGGGAQEDCFTFLATDRKNQGFVVDGKVQKEPVLFIIQVDQLDKKAPRITRLHSPSQVGLLKNGCYGIYITSHVLKASDPDTEDDQIIFKILRGPLHGRLENTTTGEFIHEQFSQKDLSRKTILYIINPSLQVNSDILEFQAMDPTGNTAPPQRLELKWSYIEWSQTEYEVCENVGLLTLEVTRRGYSMDSAYVDIEVNQVSAVVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGRWHPLPSGSSSLTTSGSPHLERRPPPSITKGDALRGFDLTDLSQRKMTTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISVIRQPQRTVKVAELPLADKVEPTTDSNFLSQGLRPLFPKNCSVELKGLFHLEEHTHRLYQCDGIAWNVWSSQTKGLEDRSCPVGWLLHSDYCHVLVTRQKGTWATATRACREQHQGTLVTVFSRRHMQWLWAISGRKPFWIGLKNQVRTGHWEWIGGEPVAFTNWRRGPPLHPKPGKNCVLVQRRGQWQTKNCSKGKAHNFVCSRKL", "length": 2167 }, "evidence": [ { "id": "A0A8V0YPJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BN52-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "FREM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSPSWGGLGALLLLLLLPGWASPTFVRVNQGVRVMKGSSAFLSQDDLKFTIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYTHNGCPILDEDTVKLRLYRFTETDTFTETFILRVYLLEPDCNIIRMSDNALEVSEFYGLSRVIDKNLLRFDYERMASLECTVRLDPVGTHLPAHGQLVLVEPQLEEPRGDQPHSFFPESQLGTELKCPGGRCTLGLKKVGSLKVSCEEFLLMGLRYQHLGSPSPNIDYFSIQLDLTDSRSKISYKSESAWLPVYIRPGIPNQIPRAAFMAMFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLWDHTRPVSSFTWKDLRDMQIAYQPPNSSHSERRLYEVELEVYDFFFEKSAPITVHISIRTTDTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIHAVQVVTVDGLQHGRLTVRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDSQHSIQHKFPINILPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDMDSSDDYIFFNITKPPQAGEIMKKPAPGLIGYPVPGFIQRDLFNGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVTIHVTPVNDQLPKEAPGVSRHLVVKETEVAYITKKHLHFIDTESQDRELLYTITTPPFFSSSRRHLDAGKLFMVDSIPRLTKTPAAPGLKYFTQHAVNHMKVAYMPPMQDVGPHPRHVQFAFSVSNQHGGTLYGICFNITILPVDNQAPKVFTKPLRVAEGGQCVISTQHVLVSDEDTKLDNIYLSLQSPPQHGMVELNGFPLNKGTTFPWGVLQALKLRYQHDGSEELQDDIVLQVTDGTNTAEYVLHVEVFPVNDEPPVLKADLIPMMHCSEGEEVVITSEYIFATDVDSDDLKLIFMIVGEPQHGTVRRAGVTVHQFSQEDVVAGAVTYKHTGGEIGLMPCFDTITLVVSDREAGPFVNGCCYNGPHPSVPLHESFPMYDLNITVYPVDNQPPSVAIGTTFVVDEGFSAALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENTLPSAGFEKSNMGISIASFQWKDMKALHINYVQSRHLGMEPTADKFVLYVTDGKRRSMEIPFYIIINATNDEAPDFIVQNITVCEGQMRELDSSIISATDRDIPKNPLLFSITHKPRHGLLINRAFSRNFFQYKQLANPGQKHELVYNFSMELLKNGMRLVYVHDDSESLADDFTIQVSDGKHKILKTIFVEVTPVNDEKPMLSKKAEITINMGETRIISSAVLSAIDEDSPREKIYYIFERIPQNGQLQLKIGRDWVPLYPGMKCTQEEVDLNLLRYTHTGAMDSKNQDSFTFRLWDGDNRSPAFDCHITIKNMGKGDIVILAKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPQFGQVEYVRYPGVPITSFSQMDIAGQTVCYVDKSTTAVHRDTFRFIVSNGLQTKPGVFEITLETVDTALPVVTRNKGLRLVEGATGLLSPDLLQLTDPDTPAEKLTFLLAQLPRHGQLYLRGMALIPHNFTQLDVDSGHVAYRHLGGDSWTDHFTFVATDGTNHGFLVDGRVWQEPVSFTIQVDQLDKAAPRVTHLHSPSQVGLLKNGCYGIYITSRVLKASDPDTDDNQIIFKILRGPQHGHLENSTTGEFIHEKFSQKDLNSKTVLYIINPSLEVNSDTMEFQVMDPTGNSATPQSLELNWSYIEWSRTEYEVCENMGMLPLEITRRGYSMDSAFVTVQVNQVSATVGKDFTMTPSKLVQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKTAVKILDSKGGQCHPSNAFNSNMPSAWEKGIWHLLSPGASSPTTSDSFHLERRPLPTSKQLAVTRGDALRDFGSEDLSPVKLRTRGDGKTVPPSSVYKNRTDIIYNYHGVISLKLEDDGSPARRRKANVSFISEPQKTTKVAEPPQADKEESTTGSHFPRQDPLPSFPKNCTPELKGLFHFEESLQKLYKCDGIAWRSWSPHTKEVEDKSCPAGWHHHSGYCHSLITEQKGTWTTAAQACREHYQGSLVTVISRQHMRWLWDISGRKPFWIGLNDQVRAGHWEWIGGEPVTFTNWRRGPPQRSRHGKDCVLVQRPGKWHTKDCRKGKSHSYVCSRKL", "length": 2180 }, "evidence": [ { "id": "A0A8V0YPJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5H8C1-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "FREM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFHLERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTIKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAKPHNYVCSRKL", "length": 2179 }, "evidence": [ { "id": "A0A8V0YPJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q684R7-1", "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSPGCTGPKAQWFLLLQLLLLHLDRVSATFISINRGLRVMKGSSAFLSGDHLRVAVPKEKDACRLEVVMNEPVTQRVGKLSPQVFDCHFLPNEVKYVHNGCPILDEDSVKLRLYRFTETDTFMETFLLRVYLVEPDCNIIRMSSNVLEVTEFYGLSQAIDKNLLQFDYDRTASLDCTIRLDPLRTQLPAHGKLVVVNRKSEGPRGDQPHSFFSETELGAGLKCPDGSCALELKQVASLKVSCEEFLLTGFHYQHMQPPSPNIDYIPIQLDLTDRRSKTVYKSESAWLPVYIRVGIPNQVPRAAFMAMFVLEVDQFILTPLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQVAYQPPNSSHPERRHYTMELEVYDFFFERSAPITVHISIRTADTNAPRVSWNTGLNLLEGQSRAITWEQFQIVDNDDIGAVQLVTIGGLQHGRLTVREGKGFLFTVTDLQAGVVRYHHDDSDTTKDFVAFRIFDGHHSSHHKFPINILPKDDSPPFLITNVVIELEEGKTILIQGSMLRASDMDSSDDYIFFNITKFPQAGEIMKKPGPRLIGYPVPGFLQRDLFSGIIYYRHFGGEIFEDSFEFVLWDSHEPPNLSVPQVVTIHITPVDDQLPKEAPGISRHLVVKETEVAYITKKHLHFLDMESRDGELIYTVTRPPCFSFSHRHLDAGKLFMVDSIPKLTKNPTAPGLSSFTQGLILISANQHTCSSQFASQHAVNHMKVAYMPPMQDIGPSPRHVQFTVSVSNQHGGALHGICFNITVLPVDNQVPEVFTNTLRVVEGGQCTISTEHILVSDVDTPLDSISLSLKERPLHGGVELDGFPLNPRGTFSWRDLNTLKVWYQHDGSEVLQDEIFLEVTDGTNSAAFVLHIEVFPVNDEPPILKADLIPMMHCSEGGEVTITPEYISATDADSDDLELLFLIAREPQHGVVRKAGLHVDRFSQGDVISGAVTYKHTGGEIGLEPCSDTVVLVVSDGEADPLMNGCCYDGPDSSVPLHKSFPTYQLNITVHPVDNQPPSIIIGRMLTVDEGFSAALTTHHLTVVDWDTAPDDLKFMLASQPQFGYLENALPSAGFEKSNIGIRIASFQWTDMKASHINYVQSRHLRVEPTADQFTVYATDGKHRSLETTFHVIINPTNDEAPDLAVQNITVYEGHMVELDSSIISATDRDIPKDPLLFSIALKPQHGLLVDAAISKDSHQIKQLQHEIHSFSVDLLKNGMKLVYAHDDSESSADNFVIQLSDGKHKILKTISVNITPVNDETPTLSKKAEISMAVGDTRVLSSAVLSATDKDSPREKIHYVFERLPQNGQLQLKIGRDWVPLSTGMQCTQEDVDLNLLRYTHAGKTDSQDGDSFTFYLWDEDNRSPAFDCHIIIEDMGKGDIVIHAKPLVVVKGDRGLLTTATLLAVDGADKPEELLYLITSPPRHGQVEYVHSPGVPIASFSQMDIAGQTVCYIHKSRTAVPTDSFRFTISNGLQTQRGVFEITLQTVDSALPVLTKNKRLRLAEGAMGLLSADHLQLTDPDTPPENLTFFLAQLPRHGYLFLRGKALQHNFTQRDVDSGGVAYQHSGGGAREDYFTFLATDRKNQGFVVDGKVQKEPVRFTIQVDQLDKAAPRITHLHSPTQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILRGPLYGRLENTTTGEFIHERFSQKDLSHKTILYIINPSLQVTSDILEFQAMDPTGNTATPQSLDLRWSYIEWAQTAYEVCENVGLLPLEVTRRGYPMDSAFVGVEVNQVSATVGKDFTVTPSKLLQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTQTKAAVKILDSKGGRCHPSNSFNQSKHSTWGKGPWHPLPSGSSSLTTSGSPLLERPPPSFTSGDALQGFGLTDLTQRKTMTQGNGKSVLPSSVCRNGTDTIYNYHGIVSLKLEGDRFSAHKRKAKISIVSQPQRTIKVAELPLADKVESTTDLHFLRQGLRPLFPKNCSVDLKGLFHFEESTHRLYQCDGISWKAWSPQTKGLEDRSCPGGWLLHSGYCHILVTRQKGTWTTATRACREQHQGDLVTVLSRRHMQWLWAMSGRKPFWIGLKNQPRTGHWEWIGGEPVAFTNWRRGAPLHPKPGKNCALVQKRGQWQTKNCSKGKAHNFVCSRKL", "length": 2191 }, "evidence": [ { "id": "A0A8V0YPJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "craniofacial suture morphogenesis", "id": "GO:0097094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1014, "end_pos": 1016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1376, "end_pos": 1378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1541, "end_pos": 1543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1830, "end_pos": 1832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1941, "end_pos": 1943, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ1" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 2065, "end_pos": 2172, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1014, "end_pos": 1016 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 1376, "end_pos": 1378 }, { "start_pos": 1541, "end_pos": 1543 }, { "start_pos": 1683, "end_pos": 1685 }, { "start_pos": 1830, "end_pos": 1832 }, { "start_pos": 1941, "end_pos": 1943 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPM5-1", "uniprot_ac": "A0A8V0YPM5", "uniprot_id": "A0A8V0YPM5_CHICK", "mass": { "chemical_mass": 54917.0, "monoisotopic_mass": 54917.0 }, "refseq": { "ac": "XP_040553476", "name": "zinc finger-containing ubiquitin peptidase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553476" }, "gene_names": [ { "name": "ZUFSP", "type": "recommended", "evidence": [ { "id": "A0A8V0YPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ] }, { "name": "ZUFSP", "type": "synonym", "evidence": [ { "id": "XP_040553476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553476" } ] } ], "protein_names": [ { "name": "Zinc finger-containing ubiquitin peptidase 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A8V0YPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5/entry#names_and_taxonomy" } ] }, { "name": "Lys-63-specific deubiquitinase ZUFSP", "type": "synonym", "evidence": [ { "id": "A0A8V0YPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger with UFM1-specific peptidase domain protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger-containing ubiquitin peptidase 1", "type": "synonym", "evidence": [ { "id": "XP_040553476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553476" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040553476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553476" } ] }, { "annotation": "Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5#function" }, { "database": "UniProtKB", "id": "ARBA00045669", "url": "https://www.uniprot.org/uniprotkb/ARBA00045669#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZUFSP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YPM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "421739", "url": "https://www.ncbi.nlm.nih.gov/gene/421739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGSKAWI", "url": "https://omabrowser.org/oma/group/CGSKAWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPM5", "url": "https://www.orthodb.org/?gene=A0A8V0YPM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040553476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVCGICGQVLPSEAAARRHVNRAHPDRQPRCPLCSAAASGYEELRQHVEAAHPEPQPLPRARSPELECPFCGEVAGRQLEAHVRARHERLLGADTENVEQLYECPICGLTCTDIRILEEHVDLHLEEHSFPEGGSSGDLELAQQLQSEEDKQQRLEEEKREKEEFKKLQRQYGLDSSGGYKKQFLNNMEREVNRGRMQPFEYHKRKADMMECLAFGIDDGKTKTSGITEALCKYYQNENKDVRRVWLSAGVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNSLYNDCLRDIALIPSIPKIQSMIEDAWKEGFDPHGASHFNNRLCGSKAWIGACEIYSLLTSLRIKCQIIDFHKPTGPTGTHPRLFEWILRYYSTDNEGAAKVVCTSRPPVYLQHQGHSRTVVGIEEKKNKALCLLLFDPGCPSQEMQKLLKLSSDGTSLKLLRKFMGSLKEKQYQIVTVDGVLTLEEKTARCLASRVLTSEKIP", "length": 485, "header": "tr|A0A8V0YPM5-1|A0A8V0YPM5_CHICK Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Gallus gallus OX=9031 GN=ZUFSP PE=3 SV=1 CANONICAL=A0A8V0YPM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5/entry", "sequence": { "sequence": "MSVCGICGQVLPSEAAARRHVNRAHPDRQPRCPLCSAAASGYEELRQHVEAAHPEPQPLPRARSPELECPFCGEVAGRQLEAHVRARHERLLGADTENVEQLYECPICGLTCTDIRILEEHVDLHLEEHSFPEGGSSGDLELAQQLQSEEDKQQRLEEEKREKEEFKKLQRQYGLDSSGGYKKQFLNNMEREVNRGRMQPFEYHKRKADMMECLAFGIDDGKTKTSGITEALCKYYQNENKDVRRVWLSAGVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNSLYNDCLRDIALIPSIPKIQSMIEDAWKEGFDPHGASHFNNRLCGSKAWIGACEIYSLLTSLRIKCQIIDFHKPTGPTGTHPRLFEWILRYYSTDNEGAAKVVCTSRPPVYLQHQGHSRTVVGIEEKKNKALCLLLFDPGCPSQEMQKLLKLSSDGTSLKLLRKFMGSLKEKQYQIVTVDGVLTLEEKTARCLASRVLTSEKIP", "length": 485, "header": "tr|A0A8V0YPM5-1|A0A8V0YPM5_CHICK Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Gallus gallus OX=9031 GN=ZUFSP PE=3 SV=1 CANONICAL=A0A8V0YPM5-1" }, "locus": { "chromosome": "3", "start_pos": 63482900, "end_pos": 63476852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035397.1", "url": "https://www.ensembl.org/id/ENSGALT00010035397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020600.1", "url": "https://www.ensembl.org/id/ENSGALP00010020600.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 359, "start_aa": "Thr", "end_pos": 359, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr359", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TE28-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "ZUP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLIVHMEDDVICPFCKLSGVSYDEMCFHIETAHFEQNELERNIERINSVQYGTSDNRTDSTLQCRMEVNSSIHSACASNHPKILAQSLPKEGSLKHKGFHSENVTESRKFLKSKEKQSDLTKIKGSIYETMYSPPECPFCGKIEDCSQDMETHVKTKHTNLLDTPLEDCDEPLYDCPMCGLICTNYHILQEHVDLHLEESGFGQGMDRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFRKLQRQYGLDNSGGYKQQQLRNMEIEVNRGKMHPSEFHRRKADMMESLAIGIDDGKTKTSGIMEALYRYYQNAATDVRRVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYGDCLKDMSVPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYTLLTSLRIKCRIIDFHKSTGPLGTHPRLFEWILNYYSSEREGSPKVVCTSKPPIYLQHQGHSRTIVGIEERKNRTLCLLIFDPGWPSRDMQKFLKQDMEASSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 578 }, "evidence": [ { "id": "A0A8V0YPM5", "url": "https://omabrowser.org/oma/group/A0A8V0YPM5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I567-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSCDICGETVTSEPDMKAHLVVHMESEVTCPFCKLSGINYDEMCFHIETAHFEQNTPERNFERLNAIQYENPDSKNTTLQSTTEVNSSIHSACASNFPKNSSHHLPKDGTLKHEAFHTESITESRKCLKSPEKQSGLSVVQGSIYETTYSPPECPFCGKIEERSQDMEMHVKTEHASLLETPPEDCHQPLYDCPMCGLICTNYHILQEHVDLHLDESSFQQGMDRVQCSGDRELAEQLQQEEDRKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMEIEVNRGRMHPSEFHSRKADMMESIAIGIDDGKTKTSGIIEALHRYYQNIATDVRCVWLSTMVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDVYGDCLKGMSIPCIPKIQSMIEDAWKEGFDPQGACQLNNKLQGTKAWIGACEIYTLLTSLRVKCRIIDFHKSTGPSGTHPRLFEWILNYYSSEREGNSKVVCTSKPPVYLQHQGHSRTIVGIEERKNRTLCLLVFDPGCPSREMQKLLKQDIEAGSLRQLRKSVGNLKHKQYQIVAVEGVLSPEEKVARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A8V0YPM5", "url": "https://omabrowser.org/oma/group/A0A8V0YPM5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3T9Z9-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSCNICGETVNSEPDMKAHLIVHMENEIICPFCKLSGINYNEICFHIETVHFEQNAPEKNSEKLAAVQYGHSDRKNTNLQSTAEVTSGIHSACASSFPKESSESLPKDRTVKHEAFYTENITESRKYQKSREKKPGLSEAQGSIYETTYSPPECPFCGKIEGCSQDMEIHVKTKHASLLESPLKDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEESSFQQGMDRVQCSSDRELAHRLQQEEDRKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMELEVNRGRMHPSEFHSRKADMLESIAIGIDDGKTKTSGIIEALHRYYQNTATDVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQSDVYGDCLKGMAVPCIPKIQSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLRVKCRIIDFHKSTGPLGTHPRLFEWILNYYSSETEGTPKIVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEASSLRQLRKSVGNLKHKQYQIVAVEGVLSPEEKVARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A8V0YPM5", "url": "https://omabrowser.org/oma/group/A0A8V0YPM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U2S3-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "Zup1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCDICGETVTSEPDRKAHLIVHMENEIICPFCKLSGINYNEMCFHIETAHFEQTTPEKSFETLAAVQYENSDLGNTKLHSTVEVTSGIHSACASNFPKESSESLSKDRTLKQEAFYTESVAESRKYQKSREKQSGLSEAQGSIYETTYSPPECPFCGRIERYSQDMEIHVKTKHASLLESPLEDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEESSFQQGMDRVQCSSDRELAHQLQQEEERKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMELEVTRGRMHPSEFHSRKADMLESIAVGIDDGKTKTSGIIEALHRYYQNIATDVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNEVYSDCLKGMSVPCIPKIQSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLKVKCRIIDFHKSTGPSGTHPRLFEWILNYYSSETEGAPKVVCTSKPPVYLQHQGHSRTVVGIEERKNRTLCLLIFDPGCPSREMQKLLKQDMEAGSLRQLRKCVGNLKHKQYQIVAVEGILSPEERAARKQASQVFTAEKIP", "length": 577 }, "evidence": [ { "id": "A0A8V0YPM5", "url": "https://omabrowser.org/oma/group/A0A8V0YPM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96AP4-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "ZUP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSCNICGETVTSEPDMKAHLIVHMESEIICPFCKLSGVNYDEMCFHIETAHFEQNTLERNFERINTVQYGTSDNKKDNTLQCGMEVNSSILSGCASNHPKNSAQNLTKDSTLKHEGFYSENLTESRKFLKSREKQSSLTEIKGSVYETTYSPPECPFCGKIEEHSEDMETHVKTKHANLLDIPLEDCDQPLYDCPMCGLICTNYHILQEHVDLHLEENSFQQGMDRVQCSGDLQLAHQLQQEEDRKRRSEESRQEIEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMPPSEFHRRKADMMESLALGFDDGKTKTSGIIEALHRYYQNAATDVRRVWLSSVVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYILLTSLRVKCHIVDFHKSTGPLGTHPRLFEWILNYYSSEGEGSPKVVCTSKPPIYLQHQGHSRTVIGIEEKKNRTLCLLILDPGCPSREMQKLLKQDIEASSLKQLRKSMGNLKHKQYQILAVEGALSLEEKLARRQASQVFTAEKIP", "length": 578 }, "evidence": [ { "id": "A0A8V0YPM5", "url": "https://omabrowser.org/oma/group/A0A8V0YPM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-2465890", "name": "DDR2 binds collagen type I, II, III, V, X fibrils", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": 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"ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": 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{ "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025011171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011171", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAPPDRPVGSVRRTHRKIPLMEAEEQEEDASSLSKSDSETNSRVCLRYVSLGIVFLLLAGAAAATWYFLDYKPWHLEPTILHFYSGSLQVLNRRYFSELGQVESRAFWLESAKLQNMLKDLIHSTELGRYYNSSTVYAFGEGALTFFFWFTLQIPESQQKEMTAERVNAVLHQELTTSFNSSGSLSYQAEYRVNPDSLILLESTVKDIVVLKSTLGCYRYSYVQEDDILRLEGPDYLASSCLWHLHSLKGYMIKLRLEWTLPDCRDRLAMYDAAGPLEKHLITSIYGCSRQEPVVEVLSSGPVMSIVWKKALYSYYDPFVLSAQVVPLKACGVNITLREGLELQGKISTPHYPSYYSPNTQCTWHMSVPSLDYGVTLWFDAYALSRQKQDLPCTQGQWIIQNRRLCGLRTLQAYAERIPVTSSADIAITFTSQISLTGPGVQAAYSLYNQSDPCPREFLCSVNGLCVPACDGIKDCPNGLDERNCVCPAKFQCQEDSTCIEFSRVCNQQRDCVNGSDEEQCNEGVPCSPFTHRCDDGTCVKKPNPLCDATVDCKDLSDEKHCDCGLQAPLSRIIGGANSVEGEWPWQASLQVRGRHICGGTLIADRWVVSAAHCFQDERLASPSVWTIYLGKYFQNTTSHTEVSFKVIRLFLHPYYEEDSHDYDVALLQLDHPVIISPFIQPICLPATSHLFEPGLHCWITGWGALKEGGHISNILQKVDVQIIQQDICSEAYHYMISPRMLCAGYNKGKKDACQGDSGGPLACEEPSGRWFLAGLVSWGMGCGLPNYYGVYTRITQVLGWMNQTMS", "length": 809, "header": "tr|A0A8V0YPR8-1|A0A8V0YPR8_CHICK Isoform 1 of Transmembrane serine protease 6 OS=Gallus gallus OX=9031 GN=TMPRSS6 PE=4 SV=1 CANONICAL=A0A8V0YPR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8/entry", "sequence": { "sequence": "MVAAPPDRPVGSVRRTHRKIPLMEAEEQEEDASSLSKSDSETNSRVCLRYVSLGIVFLLLAGAAAATWYFLDYKPWHLEPTILHFYSGSLQVLNRRYFSELGQVESRAFWLESAKLQNMLKDLIHSTELGRYYNSSTVYAFGEGALTFFFWFTLQIPESQQKEMTAERVNAVLHQELTTSFNSSGSLSYQAEYRVNPDSLILLESTVKDIVVLKSTLGCYRYSYVQEDDILRLEGPDYLASSCLWHLHSLKGYMIKLRLEWTLPDCRDRLAMYDAAGPLEKHLITSIYGCSRQEPVVEVLSSGPVMSIVWKKALYSYYDPFVLSAQVVPLKACGVNITLREGLELQGKISTPHYPSYYSPNTQCTWHMSVPSLDYGVTLWFDAYALSRQKQDLPCTQGQWIIQNRRLCGLRTLQAYAERIPVTSSADIAITFTSQISLTGPGVQAAYSLYNQSDPCPREFLCSVNGLCVPACDGIKDCPNGLDERNCVCPAKFQCQEDSTCIEFSRVCNQQRDCVNGSDEEQCNEGVPCSPFTHRCDDGTCVKKPNPLCDATVDCKDLSDEKHCDCGLQAPLSRIIGGANSVEGEWPWQASLQVRGRHICGGTLIADRWVVSAAHCFQDERLASPSVWTIYLGKYFQNTTSHTEVSFKVIRLFLHPYYEEDSHDYDVALLQLDHPVIISPFIQPICLPATSHLFEPGLHCWITGWGALKEGGHISNILQKVDVQIIQQDICSEAYHYMISPRMLCAGYNKGKKDACQGDSGGPLACEEPSGRWFLAGLVSWGMGCGLPNYYGVYTRITQVLGWMNQTMS", "length": 809, "header": "tr|A0A8V0YPR8-1|A0A8V0YPR8_CHICK Isoform 1 of Transmembrane serine protease 6 OS=Gallus gallus OX=9031 GN=TMPRSS6 PE=4 SV=1 CANONICAL=A0A8V0YPR8-1" }, "locus": { "chromosome": "1", "start_pos": 51532075, "end_pos": 51513902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035537.1", "url": "https://www.ensembl.org/id/ENSGALT00010035537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020649.1", "url": "https://www.ensembl.org/id/ENSGALP00010020649.1" } ] } }, { "isoform_ac": "A0A8V0YPS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS2/entry", "sequence": { "sequence": "MEAEEQEEDASSLSKSDSETNSRVCLRYVSLGIVFLLLAGAAAATWYFLDYKPWHLEPTILHFYSGSLQVLNRRYFSELGQVESRAFWLESAKLQNMLKDLIHSTELGRYYNSSTVYAFGEGALTFFFWFTLQIPESQQKEMTAERVNAVLHQELTTSFNSSGSLSYQAEYRVNPDSLILLGCYRYSYVQEDDILRLEGPDYLASSCLWHLHSLKGYMIKLRLEWTLPDCRDRLAMYDAAGPLEKHLITSIYGCSRQEPVVEVLSSGPVMSIVWKKALYSYYDPFVLSAQVVPLKACGVNITLREGLELQGKISTPHYPSYYSPNTQCTWHMSVPSLDYGVTLWFDAYALSRQKQDLPCTQGQWIIQNRRLCGLRTLQAYAERIPVTSSADIAITFTSQISLTGPGVQAAYSLYNQSDPCPREFLCSVNGLCVPACDGIKDCPNGLDERNCVCPAKFQCQEDSTCIEFSRVCNQQRDCVNGSDEEQCNEGVPCSPFTHRCDDGTCVKKPNPLCDATVDCKDLSDEKHCDCGLQAPLSRIIGGANSVEGEWPWQASLQVRGRHICGGTLIADRWVVSAAHCFQDERLASPSVWTIYLGKYFQNTTSHTEVSFKVIRLFLHPYYEEDSHDYDVALLQLDHPVIISPFIQPICLPATSHLFEPGLHCWITGWGALKEGGHISNILQKVDVQIIQQDICSEAYHYMISPRMLCAGYNKGKKDACQGDSGGPLACEEPSGRWFLAGLVSWGMGCGLPNYYGVYTRITQVLGWMNQTMS", "length": 773, "header": "tr|A0A8V0YPS2-1|A0A8V0YPR8_CHICK Computationally mapped isoform of Transmembrane serine protease 6 OS=Gallus gallus OX=9031 GN=TMPRSS6 PE=4 SV=1 CANONICAL=A0A8V0YPR8-1" }, "locus": { "chromosome": "1", "start_pos": 51532075, "end_pos": 51514605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035534.1", "url": "https://www.ensembl.org/id/ENSGALT00010035534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020647.1", "url": "https://www.ensembl.org/id/ENSGALP00010020647.1" } ] } }, { "isoform_ac": "A0A8V0YWI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI1/entry", "sequence": { "sequence": "MEAEEQEEDASSLSKSDSETNSRVCLRYVSLGIVFLLLAGAAAATWYFLDYKPWHLEPTILHFYSGSLQVLNRRYFSELGQVESRAFWLESAKLQNMLKDLIHSTELGRYYNSSTVYAFGEGALTFFFWFTLQIPESQQKEMTAERVNAVLHQELTTSFNSSGSLSYQAEYRVNPDSLILLESTVKDIVVLKSTLGCYRYSYVQEDDILRLEGPDYLASSCLWHLHSLKGYMIKLRLEWTLPDCRDRLAMYDAAGPLEKHLITSIYGCSRQEPVVEVLSSGPVMSIVWKKALYSYYDPFVLSAQVVPLKACGVNITLREGLELQGKISTPHYPSYYSPNTQCTWHMSVPSLDYGVTLWFDAYALSRQKQDLPCTQGQWIIQNRRLCGLRTLQAYAERIPVTSSADIAITFTSQISLTGPGVQAAYSLYNQSDPCPREFLCSVNGLCVPACDGIKDCPNGLDERNCVCPAKFQCQEDSTCIEFSRVCNQQRDCVNGSDEEQCNEGVPCSPFTHRCDDGTCVKKPNPLCDATVDCKDLSDEKHCDCGLQAPLSRIIGGANSVEGEWPWQASLQVRGRHICGGTLIADRWVVSAAHCFQDERLASPSVWTIYLGKYFQNTTSHTEVSFKVIRLFLHPYYEEDSHDYDVALLQLDHPVIISPFIQPICLPATSHLFEPGLHCWITGWGALKEGGHISNILQKVDVQIIQQDICSEAYHYMISPRMLCAGYNKGKKDACQGDSGGPLACEEPSGRWFLAGLVSWGMGCGLPNYYGVYTRITQVLGWMNQTMS", "length": 787, "header": "tr|A0A8V0YWI1-1|A0A8V0YPR8_CHICK Computationally mapped isoform of Transmembrane serine protease 6 OS=Gallus gallus OX=9031 GN=TMPRSS6 PE=4 SV=1 CANONICAL=A0A8V0YPR8-1" }, "locus": { "chromosome": "1", "start_pos": 51532075, "end_pos": 51514605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035541.1", "url": "https://www.ensembl.org/id/ENSGALT00010035541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020651.1", "url": "https://www.ensembl.org/id/ENSGALP00010020651.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418046", "resource": "KEGG Pathway" }, { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G6J0-1", "protein_name": "Transmembrane protease serine 6", "gene_name": "Tmprss6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRCFQLPCSTRMPTAEVPQAAGGQGDGGDGEEAAEPEGVFKAPRNAKRKDRDYVRFTPLLLVLAALASAGVMLWYFLGYKAEVTISQVYSGSLRVLNRHFSQDLARRESIAFRTETAKAQKMFQELVASTRLGTYYNSSSIYAFGEGPLICFFWFILDIPEYQRLTLSPEVVRELLVGELLSNSSALASYRTEYEVDPEGLVILEASVNDIVVLNSTLGCYRYSYVNPGQVLRLRGPDQQTTSCLWHLQGPEDLMLKVQLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGLHSFYDPFLLSVKSVAFQDCQVNLTLEGRLDPQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNLLCTQGQWMIQNRRLCGFRTLQPYAERIPVVASDGITINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQADCRDGSDEEHCDCGLQGPSSRIVGGAMSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPRLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPGSSTLQKVDVQLIPQDLCNEAYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKEPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVVNWIQQVLT", "length": 811 }, "evidence": [ { "id": "A0A8V0YPR8", "url": "https://omabrowser.org/oma/group/A0A8V0YPR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7FKC3-1", "protein_name": "Transmembrane protease serine 6", "gene_name": "Tmprss6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRCFHLPCSTRMPTAEVPQVGGQGDGGDGEEAADPEGMFKTPKNSKRKTRDYTRFSPLLLVFAALASAGVMLWYFLGYKTEVTISQVYSGSLRVLNRHFSQDLARRESSAFRSETAKAQKMLKELIASTHLGAYYNSSSIYSLGEGSLTCFFWFILDIPEYQRLTLNPEVVHELLVGELLSNSSTLASYRTEYEVDPESLVILEASVNDIVVLNSTLGCYRYSYVKPGQVLRLRGPDQLASSCLWHLQGPEDLMLKVRLEWTQVDCRDRVAMYDAAGPLEKRLITSVYGCNRQEPVMEVLASGSVMAVVWKKGLHSYYDPFMLSVKSVAFQDCQVNLTLEGRLDLQGFLSTPYYPSYYSPRTHCSWHLTVPSLDYGLALWFDAYALRRQKYNLLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASAGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDQQPDCLNGSDEEQCQEGVPCGTFTFQCEDQSCVKKPNPECDGQLDCSDGSDEKHCDCGLQGPSSRIVGGSVSSEGEWPWQASLQIRGRHICGGALITDRWVITAAHCFQEDSMASPRLWTVFLGKIRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVFSATVRPICLPARSHFFEPGQFCWITGWGALREGGPSSSTLQKVDVQLVPQDLCSEAYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRITRVINWIQQVLT", "length": 810 }, "evidence": [ { "id": "A0A8V0YPR8", "url": "https://omabrowser.org/oma/group/A0A8V0YPR8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8IU80-4", "protein_name": "Transmembrane protease serine 6", "gene_name": "TMPRSS6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT", "length": 811 }, "evidence": [ { "id": "A0A8V0YPR8", "url": "https://omabrowser.org/oma/group/A0A8V0YPR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBI0-1", "protein_name": "Transmembrane protease serine 6", "gene_name": "Tmprss6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRCFQLPCSTRMPTTEVPQAADGQGDAGDGEEAAEPEGKFKPPKNTKRKNRDYVRFTPLLLVLAALVSAGVMLWYFLGYKAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRSESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPLTCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNSSTLASYKTEYEVDPEGLVILEASVNDIVVLNSTLGCYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDLMIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVYGCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLLSVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYYSPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNRLCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGVTINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCSVNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQEDSTCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVINWIQQVLT", "length": 811 }, "evidence": [ { "id": "A0A8V0YPR8", "url": "https://omabrowser.org/oma/group/A0A8V0YPR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "membrane protein proteolysis", "id": "GO:0033619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033619", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "self proteolysis", "id": "GO:0097264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "multicellular organismal-level iron ion homeostasis", "id": "GO:0060586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR8" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 333, "end_pos": 450, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YPR8", "database": "UniProtKB", "url": 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Classification" ] }, { "id": "A0A8V0YRI1", "url": "https://www.orthodb.org/?gene=A0A8V0YRI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14150:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS6-1", "url": 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"MATATSRAGRKCGASRRAEASHSTALCDAMAEEWLGAEAAGSGSEEEEEEQEDGERRHQQLLEAVSALTGRKRRKLAERSEASAQVSEFNVSCKGAGEKLVLSELLQPIRARSALSGVKKELSRVKQKKAVELPLSKEEAERVVREAAYAKSSKDVGKWQPVVLQNRRAEQLVFPLKEEIVAVAPLEQVVSAWKPRTPLEQEIFGLLHKTQQPITDPLLTPQEKASLQAMSLEEAKRRRAELQKARVLQSYYEAKARREKKIKSKKYHRVLKKSKRRKALKEFEMLQKSDPEAALAKLEELDQLRMEERMSLKHQNKGKWARSRAIMAKYDLEARKAMQEQLARNKELTQKVRVELPEEEPADVPEEDLTSTAIPPVSVGASRANPWMLGKPSDPAQEPDVPEGLGDAAVPVAVESKEEMSEEEEELSEEEALLQDFQQKRQARQQQGEGPEQHSEELTVLPGVHSVIEQGADETEVSEQLPGDGPIHPVSVEEQVSPVIELPLQAQEEPLLSEQLHRVQTMEDIEALASEELTAEQEKPVAVGTEKPACRQEEGKAAPKPAKKPTTKKKIISLQSVLSGKLQEAQCPSLPVVVVEEEGGFDQRGVITEAFAGDDVVADFNREKRKAEQAAKPQPLNLVLPGWGEWGGTGLKPSNKKIKRFLIKPAPAPPRKDQHLPHVIINEQRNIHAAAHQVSELPFPFEKHQQFEQCIRTPVGSTWNTQRAFQKLTAPRVVTRAGHIIQPISAEDVPSMAATTDTGTKLALQTAPEQHKQSSRRPRKRAR", "length": 783, "header": "tr|A0A8V0YPS6-1|A0A8V0YPS6_CHICK Isoform 1 of UTP14A small subunit processome component OS=Gallus gallus OX=9031 GN=UTP14A PE=1 SV=1 CANONICAL=A0A8V0YPS6-1" }, "isoforms": [ { 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processome component OS=Gallus gallus OX=9031 GN=UTP14A PE=1 SV=1 CANONICAL=A0A8V0YPS6-1" }, "locus": { "chromosome": "4", "start_pos": 1577960, "end_pos": 1573445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035548.1", "url": "https://www.ensembl.org/id/ENSGALT00010035548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020652.1", "url": "https://www.ensembl.org/id/ENSGALP00010020652.1" } ] } }, { "isoform_ac": "A0A8V0YRI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRI1/entry", "sequence": { "sequence": "MPFCRAIMMRPSQQKEQEDGERRHQQLLEAVSALTGRKRRKLAERSEASAQVSEFNVSCKGAGEKLVLSELLQPIRARSALSGVKKELSRVKQKKAVELPLSKEEAERVVREAAYAKSSKDVGKWQPVVLQNRRAEQLVFPLKEEIVAVAPLEQVVSAWKPRTPLEQEIFGLLHKTQQPITDPLLTPQEKASLQAMSLEEAKRRRAELQKARVLQSYYEAKARREKKIKSKKYHRVLKKSKRRKALKEFEMLQKSDPEAALAKLEELDQLRMEERMSLKHQNKGKWARSRAIMAKYDLEARKAMQEQLARNKELTQKVRVELPEEEPADVPEEDLTSTAIPPVSVGASRANPWMLGKPSDPAQEPDVPEGLGDAAVPVAVESKEEMSEEEEELSEEEALLQDFQQKRQARQQQGEGPEQHSEELTVLPGVHSVIEQGADETEVSEQLPGDGPIHPVSVEEQVSPVIELPLQAQEEPLLSEQLHRVQTMEDIEALASEELTAEQEKPVAVGTEKPACRQEEGKAAPKPAKKPTTKKKIISLQSVLSGKLQEAQCPSLPVVVVEEEGGFDQRGVITEAFAGDDVVADFNREKRKAEQAAKPQPLNLVLPGWGEWGGTGLKPSNKKIKRFLIKPAPAPPRKDQHLPHVIINEQRNIHAAAHQVSELPFPFEKHQQFEQCIRTPVGSTWNTQRAFQKLTAPRVVTRAGHIIQPISAEDVPSMAATTDTGTKLALQTAPEQHKQSSRRPRKRAR", "length": 749, "header": "tr|A0A8V0YRI1-1|A0A8V0YPS6_CHICK Computationally mapped isoform of UTP14A small subunit processome component OS=Gallus gallus OX=9031 GN=UTP14A PE=1 SV=1 CANONICAL=A0A8V0YPS6-1" }, "locus": { "chromosome": "4", "start_pos": 1578913, "end_pos": 1573445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035552.1", "url": "https://www.ensembl.org/id/ENSGALT00010035552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020653.1", "url": "https://www.ensembl.org/id/ENSGALP00010020653.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS6" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPS8-1", "uniprot_ac": "A0A8V0YPS8", "uniprot_id": "A0A8V0YPS8_CHICK", "mass": { "chemical_mass": 39967.0, "monoisotopic_mass": 39967.0 }, "refseq": {}, "gene_names": [ { "name": "ZDHHC9", "type": "recommended", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZDHHC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8", "locus": { "chromosome": "4", "start_pos": 1589896, "end_pos": 1578365, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014797", "url": "https://www.ensembl.org/id/ENSGALG00010014797" } ] } } ], "crossref": [ { "id": "A0A8V0YPS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPS8", "url": "https://www.orthodb.org/?gene=A0A8V0YPS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9648002", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVMVARKKVVRKWEKLPGRNTFCCDGRIMMARQKGIFYLTLFLILGTCALFFAFECRYLAVQLSPAIPVFAAVLFLFAMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGTVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTIYIFTFDIVYVALKSLKIGFLNTLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNEDIKGSWTGKNRVQNPYSHGNMVKNCCEVLCGPLPPSVLDRRGILQQEENAAQEETCTRGPSAQEPTAAQGPGGQAEESSTQQDGSLPHQSPRAIPEQR", "length": 356, "header": "tr|A0A8V0YPS8-1|A0A8V0YPS8_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC9 PE=3 SV=1 CANONICAL=A0A8V0YPS8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8/entry", "sequence": { "sequence": "MSVMVARKKVVRKWEKLPGRNTFCCDGRIMMARQKGIFYLTLFLILGTCALFFAFECRYLAVQLSPAIPVFAAVLFLFAMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGTVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTIYIFTFDIVYVALKSLKIGFLNTLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNEDIKGSWTGKNRVQNPYSHGNMVKNCCEVLCGPLPPSVLDRRGILQQEENAAQEETCTRGPSAQEPTAAQGPGGQAEESSTQQDGSLPHQSPRAIPEQR", "length": 356, "header": "tr|A0A8V0YPS8-1|A0A8V0YPS8_CHICK Isoform 1 of Palmitoyltransferase OS=Gallus gallus OX=9031 GN=ZDHHC9 PE=3 SV=1 CANONICAL=A0A8V0YPS8-1" }, "locus": { "chromosome": "4", "start_pos": 1588252, "end_pos": 1578804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035587.1", "url": "https://www.ensembl.org/id/ENSGALT00010035587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020662.1", "url": "https://www.ensembl.org/id/ENSGALP00010020662.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-9648002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "resource": "Reactome", "description": "RAS processing" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "palmitoyltransferase complex", "id": "GO:0002178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "post-translational protein modification", "id": "GO:0043687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "host-mediated activation of viral process", "id": "GO:0044794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "positive regulation of pyroptotic inflammatory response", "id": "GO:0140639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140639", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "positive regulation of cGAS/STING signaling pathway", "id": "GO:0141111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" }, { "name": "Ras palmitoyltransferase activity", "id": "GO:0043849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043849", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUB9-1", "A0A1D5NVK1-1", "A0A1D5PDT8-1", "A0A1D5PVV6-1", "A0A8V0XHB8-1", "A0A8V0XMA1-1", "A0A8V0XVP6-1", "A0A8V0YMW4-1", "A0A8V0YMN9-1", "A0A8V0YME7-1", "A0A8V0YPS8-1", "A0A8V0ZFK7-1", "A0A8V1ACZ6-1", "A0A8V0Z649-1", "A0A8V0ZZH0-1", "A0A8V0ZI56-1", "A0A8V1A9I9-1", "A0A8V1AH42-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] }, { "id": "R-GGA-9647982", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "P08642-1", "A0A8V0YPS8-1" ], "evidence": [ { "id": "R-GGA-9647982", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9647982" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVK1", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5NVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVK1" } ] } ] }, { "uniprot_ac": "A0A1D5PDT8", "gene_name": "ZDHHC16", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5PDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5PDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDT8" } ] } ] }, { "uniprot_ac": "A0A1D5PVV6", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A1D5PVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVV6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A1D5PVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVV6" } ] } ] }, { "uniprot_ac": "A0A8V0XHB8", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHB8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHB8" } ] } ] }, { "uniprot_ac": "A0A8V0XMA1", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XMA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XMA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA1" } ] } ] }, { "uniprot_ac": "A0A8V0XVP6", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0XVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVP6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0XVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVP6" } ] } ] }, { "uniprot_ac": "A0A8V0YME7", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME7" } ] } ] }, { "uniprot_ac": "A0A8V0YMN9", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN9" } ] } ] }, { "uniprot_ac": "A0A8V0YMW4", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YMW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW4" } ] } ] }, { "uniprot_ac": "A0A8V0YPS8", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" } ] } ] }, { "uniprot_ac": "A0A8V0YUB9", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0YUB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0YUB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB9" } ] } ] }, { "uniprot_ac": "A0A8V0Z649", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0Z649", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z649" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0Z649", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z649" } ] } ] }, { "uniprot_ac": "A0A8V0ZFK7", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZFK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK7" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZFK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK7" } ] } ] }, { "uniprot_ac": "A0A8V0ZI56", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI56" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI56" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH0", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V0ZZH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V0ZZH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH0" } ] } ] }, { "uniprot_ac": "A0A8V1A9I9", "gene_name": "LOC100858962", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1A9I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1A9I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9I9" } ] } ] }, { "uniprot_ac": "A0A8V1ACZ6", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1ACZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1ACZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ6" } ] } ] }, { "uniprot_ac": "A0A8V1AH42", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8V1AH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH42" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8V1AH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH42" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "Q5F352", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q5F352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F352" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS8" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 261, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.225", "ec_name": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "2.3.1.225", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225" }, { "id": "2.3.1.225", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.225" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YPY4-1", "uniprot_ac": "A0A8V0YPY4", "uniprot_id": "A0A8V0YPY4_CHICK", "mass": { "chemical_mass": 134571.0, "monoisotopic_mass": 134571.0 }, "refseq": { "ac": "XP_004936089", "name": "leucine-rich repeat-containing protein 66 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936089" }, "gene_names": [ { "name": "LRRC66", "type": "recommended", "evidence": [ { "id": "A0A8V0YPY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4" } ] }, { "name": "LRRC66", "type": "synonym", "evidence": [ { "id": "XP_004936089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936089" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 66", "type": "synonym", "evidence": [ { "id": "A0A8V0YPY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 66 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004936089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936089" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936089.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936089" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YPY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422761", "url": "https://www.ncbi.nlm.nih.gov/gene/422761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422761", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422761", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NAWIFNC", "url": "https://omabrowser.org/oma/group/NAWIFNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPY4", "url": "https://www.orthodb.org/?gene=A0A8V0YPY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z391", "url": "https://www.orthodb.org/?gene=A0A8V0Z391", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24365:SF541", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24365:SF541", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z391", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z391", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z391-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z391-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNIHLSVTAVLLLYFNRPGSAGTKSQQLLNTHHHTDCWWDEKFVVNCSFMGLPAVPEDLSLTAVTADLSYNNIKTFLCTTGRNEDWMLKHLNLSNNLISEISITAFRNLPILETLNLNGNSISTLTLDPPTPARVSQTFGEIHHFLPALKVLSAERNNLHAVPTGLGLLQSLQTVHLSFNGILQIDLNDFHNCLQLKNIYLQSNKIANIHPDAFKDLNKLQVVDLRENPLTTILPHLLINLNVFQLKVDVFNNSWICNYRRHTFKHLLRFPSASMRKKLITSCSKSAASSQKPLLYLSSFHLNYNDSVLFRTAVVPPRETSVLRCSVDNTLGNGVSWWTPKGRISEESSSPHLTLDKINNLVIHNAEKTDEGLYVCAFNTARKKYLIYSVQVKERVPASLVRKTRATNPGGVRAGGTQQDLTLAVCLSVFITFLCAFCLGALARPCLTRLWMRMCRNKAPAPEHIYANHAFSDETPSREHSTSKPVNTQHNTFVLYENSSRDTHASPTQTAQLYEDVFGGIGRTPSTEEFPKQSNSEVHIKKNTVSSNTKTNSSDAMYVNTGQLTARMDYESSNEVTPRKLTGSSLSPWEDPKYANSTDSEQSRVPPTPSRHNTGSHSVQVDPADTDLPCTGDAGFPLPTVQPQTSVRDSRDNEVGNSSGQQQSEATPEYKGNISHHEPTSTTKFMSGRQIYDREFGLNSNINTNSDVGDLILPSSSKRDANIENLSVYQKPENAPHTEHSCKRDCRNERGNFADLFGDSSSDEGTPFTMSDCSSLEDFDLEQPGVSSNLPAPLSSLEKADTNGTGNSSAPLESLSIAAELRRIGKHGDKHSAYFGTTTDYGSDTIMPEAASARAAKGSDHVSTSGSDSISSSPEVPDTLGYFTKESTAQNSISDSPYKHNADFSNTALSLKHSPTYTTDTENTPEDAELQPHRFSFQPQHLLRHSPTEQKERAPEVSTEQLTDDSSSESDCGEGDTALRWNTITSENDHFDRTPLDTGLKATVTKAPLPHASTASNESLHPPLPENTTEKPSTVIMEKESLPQGEHINSARPHEDKTQRGEERDEYGELQGSSNRSPSDEMQSCSVMAKLHLESHGKTQSVFNIENYFQLDPNEENVYSSPVPPSSLSRSTQRSSGLFPQNTAGNKTCPTTNPNELEGDTSLTAPENSSTTAASLLDSSEKRYQKPQASLGQGQLFIKKKRAFDGFANILQSRRADSDG", 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"length": 1054, "header": "tr|A0A8V0Z391-1|A0A8V0YPY4_CHICK Computationally mapped isoform of Leucine rich repeat containing 66 OS=Gallus gallus OX=9031 GN=LRRC66 PE=4 SV=1 CANONICAL=A0A8V0YPY4-1" }, "locus": { "chromosome": "4", "start_pos": 65694900, "end_pos": 65686652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039863.1", "url": "https://www.ensembl.org/id/ENSGALT00010039863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023070.1", "url": "https://www.ensembl.org/id/ENSGALP00010023070.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", 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"length": 1096, "header": "tr|A0A8V0YPZ5-1|A0A8V0YPZ5_CHICK Isoform 1 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 OS=Gallus gallus OX=9031 GN=ASAP3 PE=4 SV=1 CANONICAL=A0A8V0YPZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5/entry", "sequence": { "sequence": 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"length": 1096, "header": "tr|A0A8V0YPZ5-1|A0A8V0YPZ5_CHICK Isoform 1 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 OS=Gallus gallus OX=9031 GN=ASAP3 PE=4 SV=1 CANONICAL=A0A8V0YPZ5-1" }, "locus": { "chromosome": "23", "start_pos": 2564189, "end_pos": 2547195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039882.1", "url": "https://www.ensembl.org/id/ENSGALT00010039882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023084.1", "url": "https://www.ensembl.org/id/ENSGALP00010023084.1" } ] } }, { "isoform_ac": "A0A8V0Z3A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A3/entry", "sequence": { "sequence": "MPEQLSVAEFLAVTGEDLSSPAAAAFASKLQKCRGAVGALEESLDGDQAILQRIRKYVKAIHVSGLTHVENEEQYSEALENFGNNHLSQNNHELSTGFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLLKGQLKDSRMDSKKQIEKAWKDYETKVGKMEKEKERARLAGVIQAEPSAAEVAEDTQKERRLFQLHMCEYLLKASESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQNLYPFIEKLAVSLHSLHQAQEEEVKQLTQTRDALRSILQLESKEENLSRKNSGSGYSIHQHQGNKQYGTEKSGFLYKKSDGIRKVWQKRKCGVKYGCLTISHSTINRPPVKLNLLTCQVRPHAEEKKCFDLVTHNRTYHFQAEDEQECVVWVSVLQNSKDEALSNAFKGEPNGGAASAGSGADGSVQELTKLVISEVKNMPGNKQCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLLAVSVGNTRFNEIMEATLPTQDCPKPSAGSDMSARKEFIVAKYMERRFVQRGGPSEPHRLRDAIHNRDLLALLQAFAEGHDLAKPLASPEGQQDTGELALHVAVRCADRSSLPLVDFIIQNGGTLDRVTQDGNTALHYGALYNQPNCIKLLLKGKAAFGTVNAAGETALDVARRLKHSECEELVSPLQRSFKGPSPLAASPPPACPPPPRWSCAGMDITNQTYESILVASRPPPRRAHSEELPPPLPLKNPTRGGPRSKHSPTERPELPRQTSEPHFAGLTETPAPRSLSSSSSSSSSCSAGALEGTAVPPPAVSTRSPPEVRRAAYWETRSETESGGTRRGTELSAPSPGQPPPGAVSSDVTPVKFGSESTRSYRRISGVVGKATPPQSPEDPTPSKVPPVPMPRRFAPAKGRQKRVKAVVDCKGDKARELTFSKGEVIVVTREEDEQSWVGFIEGDGSRTGVFPASFVHLLQD", "length": 970, "header": "tr|A0A8V0Z3A3-1|A0A8V0YPZ5_CHICK Computationally mapped isoform of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 OS=Gallus gallus OX=9031 GN=ASAP3 PE=4 SV=1 CANONICAL=A0A8V0YPZ5-1" }, "locus": { "chromosome": "23", "start_pos": 2562709, "end_pos": 2547195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039877.1", "url": "https://www.ensembl.org/id/ENSGALT00010039877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023080.1", "url": "https://www.ensembl.org/id/ENSGALP00010023080.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1016, "start_aa": "Thr", "end_pos": 1016, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1016", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" }, { "name": "regulation of stress fiber assembly", "id": "GO:0051492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 519, "end_pos": 641, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPZ5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": 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"class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQ13-1", "uniprot_ac": "A0A8V0YQ13", "uniprot_id": "A0A8V0YQ13_CHICK", "mass": { "chemical_mass": 33105.0, "monoisotopic_mass": 33105.0 }, "refseq": { "ac": "NP_990104", "name": "secreted frizzled-related protein 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" }, "gene_names": [ { "name": "SFRP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ] }, { "name": "SFRP-2", "type": "synonym", "evidence": [ { "id": "NP_990104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" } ] }, { "name": "SFRP2", "type": "synonym", "evidence": [ { "id": "NP_990104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" } ] } ], "protein_names": [ { "name": "Secreted frizzled-related protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13/entry#names_and_taxonomy" } ] }, { "name": "secreted frizzled-related protein 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_990104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004064.1, AF218056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140854 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Oct 1, 2021 this sequence version replaced NP_990104.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" } ] }, { "annotation": "SFRP2 may play an active role in embryogenesis, especially in development of the neural system, eyes, muscles and limbs", "evidence": [ { "database": "RefSeq", "id": "NP_990104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" }, { "database": "PubMed", "id": "17495425", "url": "https://glygen.org/publication/PubMed/17495425" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SFRP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13", "locus": { "chromosome": "4", "start_pos": 19529237, "end_pos": 19533836, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014880", "url": "https://www.ensembl.org/id/ENSGALG00010014880" } ] } } ], "crossref": [ { "id": "A0A8V0YQ13", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ13", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395546", "url": "https://www.ncbi.nlm.nih.gov/gene/395546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395546", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NFGQHDL", "url": "https://omabrowser.org/oma/group/NFGQHDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ13", "url": "https://www.orthodb.org/?gene=A0A8V0YQ13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ15", "url": "https://www.orthodb.org/?gene=A0A8V0YQ15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRLCALLLLASQCLGSTAGLFPFGEPDFSYKRSNCKPIPAPMLLCRGIEYQSMRLPNLLGHETVQEVLEQASTWIPLVQKQCHPDTRKFLCSLFAPVCIDDLDEIIQPCHSLCEEVKESCAPVMSAFGFPWPDMLDCSRFPKDNDLCIPLASSDHILPVTREAPKVCDACKNKNEDDNDIMENLCKNDFALKIKVKEIAYINGDTKITPETKSKTIYKLNGLTERDLRKIVLWLKGGLQCTCDEMNDINVPYLVMGQKQAGELVITSLKRWQKGQRAFKRFSRSIRKLQC", "length": 292, "header": "tr|A0A8V0YQ13-1|A0A8V0YQ13_CHICK Isoform 1 of Secreted frizzled-related protein 2 OS=Gallus gallus OX=9031 GN=SFRP2 PE=3 SV=1 CANONICAL=A0A8V0YQ13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13/entry", "sequence": { "sequence": "MPRRLCALLLLASQCLGSTAGLFPFGEPDFSYKRSNCKPIPAPMLLCRGIEYQSMRLPNLLGHETVQEVLEQASTWIPLVQKQCHPDTRKFLCSLFAPVCIDDLDEIIQPCHSLCEEVKESCAPVMSAFGFPWPDMLDCSRFPKDNDLCIPLASSDHILPVTREAPKVCDACKNKNEDDNDIMENLCKNDFALKIKVKEIAYINGDTKITPETKSKTIYKLNGLTERDLRKIVLWLKGGLQCTCDEMNDINVPYLVMGQKQAGELVITSLKRWQKGQRAFKRFSRSIRKLQC", "length": 292, "header": "tr|A0A8V0YQ13-1|A0A8V0YQ13_CHICK Isoform 1 of Secreted frizzled-related protein 2 OS=Gallus gallus OX=9031 GN=SFRP2 PE=3 SV=1 CANONICAL=A0A8V0YQ13-1" }, "locus": { "chromosome": "4", "start_pos": 19533749, "end_pos": 19530921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035802.1", "url": "https://www.ensembl.org/id/ENSGALT00010035802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020759.1", "url": "https://www.ensembl.org/id/ENSGALP00010020759.1" } ] } }, { "isoform_ac": "A0A8V0YQ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ15/entry", "sequence": { "sequence": "MPRRLCALLLLASQCLGSTAGLFPFGEPDFSYKRSNCKPIPAPMLLCRGIEYQSMRLPNLLGHETVQEVLEQASTWIPLVQKQCHPDTRKFLCSLFAPVCIDDLDEIIQPCHSLCEEVKESCAPVMSAFGFPWPDMLDCSRFPKDNDLCIPLASSDHILPVTREALKIKVKEIAYINGDTKITPETKSKTIYKLNGLTERDLRKIVLWLKGGLQCTCDEMNDINVPYLVMGQKQAGELVITSLKRWQKGQRAFKRFSRSIRKLQC", "length": 265, "header": "tr|A0A8V0YQ15-1|A0A8V0YQ15_CHICK Computationally mapped isoform of Secreted frizzled-related protein 2 OS=Gallus gallus OX=9031 GN=SFRP2 PE=3 SV=1 CANONICAL=A0A8V0YQ13-1" }, "locus": { "chromosome": "4", "start_pos": 19533749, "end_pos": 19530921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035798.1", "url": "https://www.ensembl.org/id/ENSGALT00010035798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020757.1", "url": "https://www.ensembl.org/id/ENSGALP00010020757.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Investigation of mRNA expression for secreted frizzled-related protein 2 (sFRP2) in chick embryos.", "journal": "The Journal of reproduction and development", "date": "2007-08", "authors": "Lin Chung-Tien, Lin Yu-Ting, Kuo Tzong-Fu", "evidence": [ { "database": "RefSeq", "id": "NP_990104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990104" } ], "reference": [ { "type": "PubMed", "id": "17495425", "url": "https://glygen.org/publication/PubMed/17495425" } ] } ], "pathway": [ { "id": "gga:395546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395546", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061II73-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "Sfrp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRGPGSLLLLVLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKTKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQREFKRISRSIRKLQC", "length": 295 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1WBV2-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "Sfrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRGPASLLLLVLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPPTEEAPKVCEACKTKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSDRDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQREFKRISRSIRKLQC", "length": 295 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R238-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "sfrp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRAYLALLVALSIPGYLDALHGLYAFDQPELFQKKSNCKPIPTNLLLCHDIEYTNMRLPNLLGHETMNEVLQQASSWTPLVQKQCHPDTKKFLCSLFAPVCLDDLDEPIQPCRSLCESVKSGCAPVMAAFGFPWPDMLDCRRFPLDNDLCIPPAGADALVPVTKEVPRVCDACKEKPENDNEIVDSLCKNDFALKIKVKEISYMNGDTKIIPETKTKMIYKTNGGVTDHDFRKTVLWLKDGLQCVCDELNDINAAYLVMGQKMDGNLVITSVKRWQKGQREFKRISRSIRKLQC", "length": 294 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RX31-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "SFRP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPQGPGSLLLLVLASHCCLGSARGLFFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKLGGELVITSVKRWQKGQREFKRISRSIRKLQC", "length": 294 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97299-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "Sfrp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGPASLLLLVLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKTKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQREFKRISRSIRKLQC", "length": 295 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HF1-1", "protein_name": "Secreted frizzled-related protein 2", "gene_name": "SFRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQGPGSLLLLFLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQREFKRISRSIRKLQC", "length": 295 }, "evidence": [ { "id": "A0A8V0YQ13", "url": "https://omabrowser.org/oma/group/A0A8V0YQ13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 29, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "branching involved in blood vessel morphogenesis", "id": "GO:0001569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001569", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ13" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0036477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of synaptic transmission, glutamatergic", "id": "GO:0051968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "transmission of nerve impulse", "id": "GO:0019226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "postsynaptic neurotransmitter receptor diffusion trapping", "id": "GO:0098970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098970", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" }, { "name": "channel regulator activity", "id": "GO:0016247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016247", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQ98-1", "uniprot_ac": "A0A8V0YQ98", "uniprot_id": "A0A8V0YQ98_CHICK", "mass": { "chemical_mass": 89628.0, "monoisotopic_mass": 89628.0 }, "refseq": {}, "gene_names": [ { "name": "GNL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98" } ] } ], "protein_names": [ { "name": "Nucleolar GTP-binding protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M1#function" }, { "database": "UniProtKB", "id": "RU364023", "url": "https://www.uniprot.org/uniprotkb/RU364023#function" }, { "database": "UniProtKB", "id": "A0A8V0YQ98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98#function" }, { "database": "UniProtKB", "id": "ARBA00054763", "url": "https://www.uniprot.org/uniprotkb/ARBA00054763#function" }, { "database": "UniProtKB", "id": "A0A8V0YWL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98", "locus": { "chromosome": "23", "start_pos": 4108266, "end_pos": 4095764, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016600", "url": "https://www.ensembl.org/id/ENSGALG00010016600" } ] } } ], "crossref": [ { "id": "A0A8V0YQ98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ98", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01858", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01858", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ98", "url": "https://www.orthodb.org/?gene=A0A8V0YQ98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWL8", "url": "https://www.orthodb.org/?gene=A0A8V0YWL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQ98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAGHERRLRAVATATRGRLRSRELEPPEVRHCAAPHAGSTRAAASGLKPRVWWSGLSVWSGPGGTMVKPRYKGRSTINPSRASTNPDRVAGAGGNNMRDRATIRRLNMYRQKERRNKRGKVIKPLQYQSTVAPGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMETVMKDPYRVVMKQSKLPMSLFHDRIKPHTSRVHILDTETFETTFGPKAQRKRPNLAASDVQSLLENAEASSECYDQGKDRDLVTEDTGVRDEAQEEIFKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHVESYLKKEKHWKHLIFVLNKCDLVPTWATKRWVAVLSQEYPTLAFHASLTNPFGKGAFIQLLRQFGKLHSDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSGDSETDIVLKGVVQVEKIKSPEDHISAVLERAKPEYIRKTYKIDFWTDTEDFLEKLASRTGKLLKGGEPDVQTVSKMVLNDWQRGRIPFFVKPPNAEGGSEPPVLEGAMTSSQSNSEKEVSESVASSIEPTEEKNNTDNEMKQLMANVRQNFGRINVAPQFSEEDLIPVDMPGFDETDSDCPEEGEQEEEEEEENEQHQDSVEEESQPTVPSARESSKAVLQALEEKIAKCKKFLDKAKAKRFSAIRIPKQLSEKVFAKSMQKAEETKENEEKGGTVKKRKRNMEKEDDEDHLGKQPCKKLTSKERRRAERQQRSKKVGVRYYETHNVKNKNKNKKKSGSEAQRSKHKKYKHKQ", "length": 789, "header": "tr|A0A8V0YQ98-1|A0A8V0YQ98_CHICK Isoform 1 of Nucleolar GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GNL2 PE=3 SV=1 CANONICAL=A0A8V0YQ98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ98/entry", "sequence": { "sequence": "MGAGHERRLRAVATATRGRLRSRELEPPEVRHCAAPHAGSTRAAASGLKPRVWWSGLSVWSGPGGTMVKPRYKGRSTINPSRASTNPDRVAGAGGNNMRDRATIRRLNMYRQKERRNKRGKVIKPLQYQSTVAPGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMETVMKDPYRVVMKQSKLPMSLFHDRIKPHTSRVHILDTETFETTFGPKAQRKRPNLAASDVQSLLENAEASSECYDQGKDRDLVTEDTGVRDEAQEEIFKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHVESYLKKEKHWKHLIFVLNKCDLVPTWATKRWVAVLSQEYPTLAFHASLTNPFGKGAFIQLLRQFGKLHSDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSGDSETDIVLKGVVQVEKIKSPEDHISAVLERAKPEYIRKTYKIDFWTDTEDFLEKLASRTGKLLKGGEPDVQTVSKMVLNDWQRGRIPFFVKPPNAEGGSEPPVLEGAMTSSQSNSEKEVSESVASSIEPTEEKNNTDNEMKQLMANVRQNFGRINVAPQFSEEDLIPVDMPGFDETDSDCPEEGEQEEEEEEENEQHQDSVEEESQPTVPSARESSKAVLQALEEKIAKCKKFLDKAKAKRFSAIRIPKQLSEKVFAKSMQKAEETKENEEKGGTVKKRKRNMEKEDDEDHLGKQPCKKLTSKERRRAERQQRSKKVGVRYYETHNVKNKNKNKKKSGSEAQRSKHKKYKHKQ", "length": 789, "header": "tr|A0A8V0YQ98-1|A0A8V0YQ98_CHICK Isoform 1 of Nucleolar GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GNL2 PE=3 SV=1 CANONICAL=A0A8V0YQ98-1" }, "locus": { "chromosome": "23", "start_pos": 4106978, "end_pos": 4095843, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040036.1", "url": "https://www.ensembl.org/id/ENSGALT00010040036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023193.1", "url": "https://www.ensembl.org/id/ENSGALP00010023193.1" } ] } }, { "isoform_ac": "A0A8V0YWL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL8/entry", "sequence": { "sequence": "MVKPRYKGRSTINPSRASTNPDRVAGAGGNNMRDRATIRRLNMYRQKERRNKRGKVIKPLQYQSTVAPGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMETVMKDPYRVVMKQSKLPMSLFHDRIKPHTSRVHILDTETFETTFGPKAQRKRPNLAASDVQSLLENAEASSECYDQGKDRDLVTEDTGVRDEAQEEIFKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHVESYLKKEKHWKHLIFVLNKCDLVPTWATKRWVAVLSQEYPTLAFHASLTNPFGKGAFIQLLRQFGKLHSDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSGDSETDIVLKGVVQVEKIKSPEDHISAVLERAKPEYIRKTYKIDFWTDTEDFLEKLASRTGKLLKGGEPDVQTVSKMVLNDWQRGRIPFFVKPPNAEGGSELRGEDQVAKNSSTKMSELFCNHLASRNPPVLEGAMTSSQSNSEKEVSESVASSIEPTEEKNNTDNEMKQLMANVRQNFGRINVAPQFSEEDLIPVDMPGFDETDSDCPEEGEQEEEEEEENEQHQDSVEEESQPTVPSARESSKAVLQALEEKIAKCKKFLDKAKAKRFSAIRIPKQLSEKVFAKSMQKAEETKENEEKGGTVKKRKRNMEKEDDEDHLGKQPCKKLTSKERRRAERQQRSKKVGVRYYETHNVKNKNKNKKKSGSEAQRSKHKKYKHKQ", "length": 750, "header": "tr|A0A8V0YWL8-1|A0A8V0YQ98_CHICK Computationally mapped isoform of Nucleolar GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GNL2 PE=3 SV=1 CANONICAL=A0A8V0YQ98-1" }, "locus": { "chromosome": "23", "start_pos": 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"MVKPRYKGRSTINPSRASTNPDRVAGAGGNNMRDRATIRRLNMYRQKERRNKRGKVIKPLQYQSTVAPGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMETVMKDPYRVVMKQSKLPMSLFHDRIKPHTSRVHILDTETFETTFGPKAQRKRPNLAASDVQSLLENAEASSECYDQGKDRDLVTEDTGVRDEAQEEIFKKGQSKRIWGELYKKRWVAVLSQEYPTLAFHASLTNPFGKGAFIQLLRQFGKLHSDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSGDSETDIVLKGVVQVEKIKSPEDHISAVLERAKPEYIRKTYKIDFWTDTEDFLEKLASRTGKLLKGGEPDVQTVSKMVLNDWQRGRIPFFVKPPNAEGGSEPPVLEGAMTSSQSNSEKEVSESVASSIEPTEEKNNTDNEMKQLMANVRQNFGRINVAPQFSEEDLIPVDMPGFDETDSDCPEEGEQEEEEEEENEQHQDSVEEESQPTVPSARESSKAVLQALEEKIAKCKKFLDKAKAKRFSAIRIPKQLSEKVFAKSMQKAEETKENEEKGGTVKKRKRNMEKEDDEDHLGKQPCKKLTSKERRRAERQQRSKKVGVRYYETHNVKNKNKNKKKSGSEAQRSKHKKYKHKQ", "length": 670, "header": "tr|A0A8V0Z3M1-1|A0A8V0YQ98_CHICK Computationally mapped isoform of Nucleolar GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GNL2 PE=3 SV=1 CANONICAL=A0A8V0YQ98-1" }, "locus": { "chromosome": "23", "start_pos": 4106978, "end_pos": 4096041, "strand": "-", "evidence": [ { "database": "Ensembl 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"id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416244", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416244", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGVCCEN", "url": "https://omabrowser.org/oma/group/HGVCCEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQK4", "url": "https://www.orthodb.org/?gene=A0A8V0YQK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXC3", "url": "https://www.orthodb.org/?gene=A0A8V0YXC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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domain 19 OS=Gallus gallus OX=9031 GN=ADAM19 PE=4 SV=1 CANONICAL=A0A8V0YQK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4/entry", "sequence": { "sequence": 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domain 19 OS=Gallus gallus OX=9031 GN=ADAM19 PE=4 SV=1 CANONICAL=A0A8V0YQK4-1" }, "locus": { "chromosome": "13", "start_pos": 10953059, "end_pos": 10925365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036094.1", "url": "https://www.ensembl.org/id/ENSGALT00010036094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020962.1", "url": "https://www.ensembl.org/id/ENSGALP00010020962.1" } ] } }, { "isoform_ac": "A0A8V0YXC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC3/entry", "sequence": { "sequence": "MRGWGLLCGIALSLLLQPPPCSAEAGSTEPQPAVLVSSWDVLRSPGGEQHPLRAEVRIRAEGQELILDLEKNGDLFAPGYTETHYSQKGQARTIPLAHTEHCFYQGVVRGREHSSVTLSSCQGLRGLIVLRSNCSYVLEPLPDSPDQHQIYRLDDLRMPAGACGHQGSMATGRNWLGDFAAGVKFPNHRVRREALQATKYVELLLVADYAEVQKHHFNIEATRLKLVEAANYVDKFYRSLNIRIALVGLEIWSNGNKCDCTENPYSTLKSFLAWSSKERVYRKHDNAQLITGVPFQGTTVGLAPVMSMCSDFQSGGVNMDHSDNAIGVAATIAHEMGHNFGMNHDSSGCCTTRAEEGGCIMASATGHPFPRVFNQCNRRELEKYLHSGGGMCLSNMPDTKRMYGGRKCGNGYLEEGEECDCGEVEECNNPCCNANNCSLKLGAECAHGSCCHECKLMSPGTLCREKSGLCDLPEYCTGQSPFCPSNSYQIDGASCEGGKAYCYNGMCLTYKDQCLQLWGPGAQPAPDTCFENVNAAGDVYGNCGKDVYGNYRKCEKRDAKCGKIQCQSSASKPVLPNAVPIDTTITLQRTRVRCRGTHVYRFENEEKEMLDPALVLTGTKCGSHHVCFEGRCQNTSIIFESESCSEKCNGNGVCNNNKNCHCNPGWAPPFCNKQGRGGSLDSGPPSPEGSSAVVIALAILASILLLIGIVLLFYYLKCWNKFVICSLKKAPQISDASGNGHANPAFKLRTPQQERKVIGFPEIPSKPPPQPAPSLRINMQQQSAFTSYSYGTGSPAGPMHPALAKDVPQRTPPSRPAPPAPRSPSSQDVLRPRPPQRALPANPVPNRSRAQPGVSPAIPLPPTRPRIPGQLQPAAENTGVRTAGAVNMLRRGQPGSSAHP", "length": 900, "header": "tr|A0A8V0YXC3-1|A0A8V0YQK4_CHICK Computationally mapped isoform of ADAM metallopeptidase domain 19 OS=Gallus gallus OX=9031 GN=ADAM19 PE=4 SV=1 CANONICAL=A0A8V0YQK4-1" }, "locus": { "chromosome": "13", "start_pos": 10953059, "end_pos": 10925535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036091.1", "url": "https://www.ensembl.org/id/ENSGALT00010036091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020961.1", "url": "https://www.ensembl.org/id/ENSGALP00010020961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416244", "resource": "KEGG Pathway" }, { "id": "R-GGA-8941237", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941237", "resource": "Reactome", "description": "Invadopodia formation" }, { "id": "R-GGA-9762292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762292", "resource": "Reactome", "description": "Regulation of CDH11 function" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPM7-1", "protein_name": "ADAM metallopeptidase domain 19", "gene_name": "Adam19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGRAGVARFCLLALALQLQWPLAACEPEWTTRGSKEDSPPLQHELIIPQWRTSESPRGGKHPLTAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTTTLKSEDHCFYHGTVRKVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDNQHRIYRSEHLKLPPGNCGFEHSRPTSKDWTLQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKHKLMEIANYVDKFYRSLSIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLTQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSTSAADGGCIMAAATGHPFPKVFSSCNRKELDRYLQSGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEDECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGKYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWAPPFCNTPGDGGSIDSGPLPPKSAGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRQQFSCPFRVSQNGGTGHANPTFKLQTPQGKRKVTNTPETLRKPSHPPPRPPPDYLRVESHPAPLPAHLNRAAGSSPEAGAQIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTVPRPGGTSLFHPPTTGPQPPRPPAVSVPKLPEYRSQRIGGITSSKI", "length": 920 }, "evidence": [ { "id": "A0A8V0YQK4", "url": "https://omabrowser.org/oma/group/A0A8V0YQK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ME22-1", "protein_name": "ADAM metallopeptidase domain 19", "gene_name": "ADAM19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPRGVGIAQLCLLVLALPGWTRRGSGEGSPQLQHELIIPQWKTAESPMREKHPLKAELRVMAEGRELILDLEKNEHLFAPAYTETCYTPSGDAQTTTLKSEDHCFYHGTVRKAEQSSVMLSTCRGMRGLIIVSSNLSYIIEPLPDSESHHRIYRSEHLKLPLGNCGFEPTARDWVPQFTNQTKKRPRRMKREDLHSMKYVELYLVADYAEFQKNGLDQDATKHKLMEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLTRKNHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMSHDSADCCSASAADGGCIMAAATGHPFPRVFNRCNRRELDRYLQSGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECENPCCNAANCTLREGAECAHGSCCHRCKLLAPGMLCREQARQCDLPEFCTGKSPQCPTNFYQMDGTPCEDGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGKHKKCNMRDAKCGKIQCQSSEARPLESNAVPIDTVIVINGRQIRCRGTHVYRGPEEEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFEMEGCAKKCNGHGVCNNNQNCHCFRGWAPPFCNTPGQGGSIDSGPMPPESAGPVVAGVFSAIFVLVALIMMYRCCKQNNKLGYLKSLALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGRRKVTNTPETLRKPSQPPPRPPPDYLHSVSPPAPSPAHLSKAARNSPGPRPSVERKESSRGPPPSRPVPPAPKCVLSQDLSRPRPPQKALPANPVPGRKNLPRPSGASILRPPPSGPPQTRPLVAPAPKFPEYRSQRAVGMTSSKI", "length": 906 }, "evidence": [ { "id": "A0A8V0YQK4", "url": "https://omabrowser.org/oma/group/A0A8V0YQK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q4N9-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 19 isoform X1", "gene_name": "adam19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRSVHLNRCTGAGAVHFPQLLLLCCCCLQLFIKCTAHFEEIFRDERWHGDSSHIHDDSEHYITFPQWISPARHKRSEMVVKHPSEAEVKITVGGEDLILQLQRNEELFSSEYQEIWYDTNGNRQFSRPSIRDHCYYHGSVKEAEGSSVVISTCAGLRGLITVNNSVSYMIQPLANQTHSQGHAVFNSRRLKLPAGTCGHHHGDGHHTESLQELIDVMAKPQRTNRERRDVSSSMKYVELMVVADHAEFVNHNRDLEKTKAKLLEAANFVDKYYKSLKIRVALIRLEIWNDQDKINVTDNPYSTLGAFLSWRRKQLPQLPNDNAQLVTGVSFHGTIIGLAPLKAMCSEYQSGGVNSDHSNSAVGIAATMAHELGHNFGMSHDSPGCCRAQAEDGGCIMAAATGAPFPRVFNSCNQNELKRYLSSGGGKCLFNPPNTRVMYGGQRCGNGYLEEGEECDCGEVEECSSPCCNAHNCTLKSGAECAHGVCCHECKLKSPGVMCRPPSGSCDLPEYCDGKSESCPANFFLMDGSSCASGSAYCYTGMCLTLEQQCLSLWGKDARPAPDLCFTDVNKAGDAFGNCGQDLMGTYRKCTERNAKCGKIQCQSSASKPLESNAVAIDTTIRSGQQKILCRGTHVWPHGHAKENQNDTLDPGLVLTGTKCGDNAICFEGECRDASFLQADECSTKCQGHGLCNNNHNCHCHSGWAPPFCGTSGPGGSLDSGPVISQSSFYLVLVLLSLSFLLALAVLGVCWCRCKQRFLSTKSPALPKTQTCINVPDTPEPKSHTTGHANPVFQPKKAPADEQATLRASPTGPPRSRHSIIRPTVKPPPIPAYAPHKHLISEPSQPSPSVNPKTRPLPPNRPPPPCPTTKPCKNPAPKTTEMLPKNGMPVSPAMLQKGKSSLMPPSGHHQNVRFQKEVSGKS", "length": 923 }, "evidence": [ { "id": "A0A8V0YQK4", "url": "https://omabrowser.org/oma/group/A0A8V0YQK4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35674-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 19", "gene_name": "Adam19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRGKHPLRAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTVRDVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHSGPTSKDWALQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKRKLMEIANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLAQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQRVGAIISSKI", "length": 920 }, "evidence": [ { "id": "A0A8V0YQK4", "url": "https://omabrowser.org/oma/group/A0A8V0YQK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H013-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 19", "gene_name": "ADAM19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGGAGAARLCLLAFALQPLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHCFYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKVSPREALKVKAGTRGLQGGRCRVEKTKQFMLLVVWTELPEQKPRAKHSCFLVPA", "length": 955 }, "evidence": [ { "id": "A0A8V0YQK4", "url": "https://omabrowser.org/oma/group/A0A8V0YQK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "metalloendopeptidase activity involved in amyloid precursor protein catabolic process", "id": "GO:1902945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "positive regulation of cell-cell adhesion mediated by cadherin", "id": "GO:2000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK4" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 407, "end_pos": 493, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A8V0YQK4", "database": "UniProtKB", "url": 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8V0YQL3-1", "uniprot_ac": "A0A8V0YQL3", "uniprot_id": "A0A8V0YQL3_CHICK", "mass": { "chemical_mass": 31354.0, "monoisotopic_mass": 31354.0 }, "refseq": {}, "gene_names": [ { "name": "FAM207A", "type": "recommended", "evidence": [ { "id": "A0A8V0YQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 207 member A", "type": "recommended", "evidence": [ { "id": "A0A8V0YQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM207A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR028160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQL3", "url": "https://www.orthodb.org/?gene=A0A8V0YQL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS91", "url": "https://www.orthodb.org/?gene=A0A8V0YS91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXA5", "url": "https://www.orthodb.org/?gene=A0A8V0YXA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31109:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31109:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RLLSFCREAAFPLPSAAPAQRAERGAARTRGSTSSCSLRFQPGLFGYGSVRSQGQAGGERGDSGEGAQLGQWEEFLRREQLPWELESASLEDWNFSSSDIFSGLTIDPDSLVKKLDLDSRSIVSSRTEAGSPWLGQIHSWLGLEEKTLLSKKEKMKLRKERWLQKIESVKLAKQKQKAEAKRKATPVVGDMQPLMEALPELSDLTAGIKGRKPSKRHEKTKAEPADFCMMKQAQKHRLLEEEVAQFHEVIADPRYKANPFLVISEHLSKRLRQEEGKPL", "length": 279, "header": "tr|A0A8V0YQL3-1|A0A8V0YQL3_CHICK Isoform 1 of Family with sequence similarity 207 member A OS=Gallus gallus OX=9031 GN=FAM207A PE=3 SV=1 CANONICAL=A0A8V0YQL3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3/entry", "sequence": { "sequence": "RLLSFCREAAFPLPSAAPAQRAERGAARTRGSTSSCSLRFQPGLFGYGSVRSQGQAGGERGDSGEGAQLGQWEEFLRREQLPWELESASLEDWNFSSSDIFSGLTIDPDSLVKKLDLDSRSIVSSRTEAGSPWLGQIHSWLGLEEKTLLSKKEKMKLRKERWLQKIESVKLAKQKQKAEAKRKATPVVGDMQPLMEALPELSDLTAGIKGRKPSKRHEKTKAEPADFCMMKQAQKHRLLEEEVAQFHEVIADPRYKANPFLVISEHLSKRLRQEEGKPL", "length": 279, "header": "tr|A0A8V0YQL3-1|A0A8V0YQL3_CHICK Isoform 1 of Family with sequence similarity 207 member A OS=Gallus gallus OX=9031 GN=FAM207A PE=3 SV=1 CANONICAL=A0A8V0YQL3-1" }, "locus": { "chromosome": "7", "start_pos": 7278736, "end_pos": 7226050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036060.1", "url": "https://www.ensembl.org/id/ENSGALT00010036060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020939.1", "url": "https://www.ensembl.org/id/ENSGALP00010020939.1" } ] } }, { "isoform_ac": "A0A8V0YS91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS91/entry", "sequence": { "sequence": "MVGKVRRPRLHCAAPRPPPRPNPAPPGPGGRSAPAAKDWNFSSSDIFSGLTIDPDSLVKKLDLDSRSIVSSRTEAGSPWLGQIHSWLGLEEKTLLSKKEKMKLRKERWLQKIESVKLAKQKQKAEAKRKATPVVGDMQPLMEALPELSDLTAGIKGRKPSKRHEKTKAEPADFCMMKQAQKHRLLEEEVAQFHEVIADPRYKANPFLVISEHLSKRLRQEEGKPL", "length": 225, "header": "tr|A0A8V0YS91-1|A0A8V0YQL3_CHICK Computationally mapped isoform of Family with sequence similarity 207 member A OS=Gallus gallus OX=9031 GN=FAM207A PE=3 SV=1 CANONICAL=A0A8V0YQL3-1" }, "locus": { "chromosome": "7", "start_pos": 7278736, "end_pos": 7225835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036066.1", "url": "https://www.ensembl.org/id/ENSGALT00010036066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020943.1", "url": "https://www.ensembl.org/id/ENSGALP00010020943.1" } ] } }, { "isoform_ac": "A0A8V0YXA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXA5/entry", "sequence": { "sequence": "RLLSFCREAAFPLPSAAPAQRAERGAARTRGSTSSCSLRFQPGLFGYGSVRSQGQAGGERGDSGEGAQLGQWEEFLRREQLPWELESASLEDWNFSSSDIFSGLTIDPDSLVKKLDLDSRSIVSSRTGLEEKTLLSKKEKMKLRKERWLQKIESVKLAKQKQKAEAKRKATPVVGDMQPLMEALPELSDLTAGIKGRKPSKRHEKTKAEPADFCMMKQAQKHRLLEEEVAQFHEVIADPRYKANPFLVISEHLSKRLRQEEGKPL", "length": 265, "header": "tr|A0A8V0YXA5-1|A0A8V0YQL3_CHICK Computationally mapped isoform of Family with sequence similarity 207 member A OS=Gallus gallus OX=9031 GN=FAM207A PE=3 SV=1 CANONICAL=A0A8V0YQL3-1" }, "locus": { "chromosome": "7", "start_pos": 7278736, "end_pos": 7226050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036062.1", "url": "https://www.ensembl.org/id/ENSGALT00010036062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020941.1", "url": "https://www.ensembl.org/id/ENSGALP00010020941.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0YQS3", "uniprot_id": "A0A8V0YQS3_CHICK", "mass": { "chemical_mass": 129527.0, "monoisotopic_mass": 129527.0 }, "refseq": {}, "gene_names": [ { "name": "MCM9", "type": "recommended", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ], "protein_names": [ { "name": "DNA helicase MCM9", "type": "recommended", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3/entry#names_and_taxonomy" } ] }, { "name": "DNA 3'-5' helicase MCM9", "type": "synonym", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3/entry#names_and_taxonomy" } ] }, { "name": "Minichromosome maintenance 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3", "locus": { "chromosome": "3", "start_pos": 62466937, "end_pos": 62408391, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015028", "url": "https://www.ensembl.org/id/ENSGALG00010015028" } ] } } ], "crossref": [ { "id": "A0A8V0YQS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17760", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17760", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQS3", "url": "https://www.orthodb.org/?gene=A0A8V0YQS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11630:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11630:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "pmid": "" }, { "name": "MutSalpha complex binding", "id": "GO:0032407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "pmid": "" }, { "name": "MutLbeta complex binding", "id": "GO:0032406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "pmid": "" }, { "name": "MutSbeta complex binding", "id": "GO:0032408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0070716", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", 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"evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": 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} ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", 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"id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": 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"activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": 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"evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": 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"https://www.uniprot.org/uniprotkb/A0A8V0YQV8" } ] } ], "protein_names": [ { "name": "Proteasome subunit beta", "type": "recommended", "evidence": [ { "id": "A0A8V0YQV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS7#function" }, { "database": "UniProtKB", "id": "RU004203", "url": "https://www.uniprot.org/uniprotkb/RU004203#function" }, { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8#function" }, { "database": "UniProtKB", "id": "R4GLB3", "url": "https://www.uniprot.org/uniprotkb/R4GLB3#function" } ] }, { "annotation": "Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS7#function" }, { "database": "UniProtKB", "id": "ARBA00049625", "url": "https://www.uniprot.org/uniprotkb/ARBA00049625#function" }, { "database": "UniProtKB", "id": "R4GLB3", "url": "https://www.uniprot.org/uniprotkb/R4GLB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8", "locus": { "chromosome": "23", "start_pos": 4641513, "end_pos": 4632735, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015046", "url": "https://www.ensembl.org/id/ENSGALG00010015046" } ] } } ], "crossref": [ { "id": "A0A8V0YQV8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026421", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419630", "url": "https://www.ncbi.nlm.nih.gov/gene/419630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419630", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKRDHDK", "url": "https://omabrowser.org/oma/group/MKRDHDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQS7", "url": "https://www.orthodb.org/?gene=A0A8V0YQS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQV8", "url": "https://www.orthodb.org/?gene=A0A8V0YQV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GLB3", "url": "https://www.orthodb.org/?gene=R4GLB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32194:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32194:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLB3", "url": "https://www.uniprot.org/uniprotkb/R4GLB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLB3-1", "url": "https://www.uniprot.org/uniprotkb/R4GLB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYLIGIQGPDYVLVAADTVAASSIVQMKHDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADYLRSRVTGSGLSPREGCQFLSPCPHLAGCFLTPTFLPPPCCDFGFRQMSHRCLSQPSLLILLVWCVYHSCSLQLPLTMSTFSWLATMTMKVLPCITWITLQLWLKLPLQHMDMVHFLPSASWTAITSQVSHVRKLWSS", "length": 228, "header": "tr|A0A8V0YQV8-1|A0A8V0YQV8_CHICK Isoform 1 of Proteasome subunit beta OS=Gallus gallus OX=9031 GN=PSMB2 PE=1 SV=1 CANONICAL=A0A8V0YQV8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS7/entry", "sequence": { "sequence": "MEYLIGIQGPDYVLVAADTVAASSIVQMKHDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADYLRSRTPYHVNLLLAGYDDHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYKPGITREEAVELLKKCLEEVSCQTLGPCDPEKGMFVCIHLLIFSCSSCRIFCSLCQKG", "length": 205, "header": "tr|A0A8V0YQS7-1|A0A8V0YQV8_CHICK Computationally mapped isoform of Proteasome subunit beta OS=Gallus gallus OX=9031 GN=PSMB2 PE=1 SV=1 CANONICAL=A0A8V0YQV8-1" }, "locus": { "chromosome": "23", "start_pos": 4640113, "end_pos": 4632820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036196.1", "url": "https://www.ensembl.org/id/ENSGALT00010036196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021039.1", "url": "https://www.ensembl.org/id/ENSGALP00010021039.1" } ] } }, { "isoform_ac": "A0A8V0YQV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8/entry", "sequence": { "sequence": "MEYLIGIQGPDYVLVAADTVAASSIVQMKHDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADYLRSRVTGSGLSPREGCQFLSPCPHLAGCFLTPTFLPPPCCDFGFRQMSHRCLSQPSLLILLVWCVYHSCSLQLPLTMSTFSWLATMTMKVLPCITWITLQLWLKLPLQHMDMVHFLPSASWTAITSQVSHVRKLWSS", "length": 228, "header": "tr|A0A8V0YQV8-1|A0A8V0YQV8_CHICK Isoform 1 of Proteasome subunit beta OS=Gallus gallus OX=9031 GN=PSMB2 PE=1 SV=1 CANONICAL=A0A8V0YQV8-1" }, "locus": { "chromosome": "23", "start_pos": 4639976, "end_pos": 4632820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036190.1", "url": "https://www.ensembl.org/id/ENSGALT00010036190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021035.1", "url": "https://www.ensembl.org/id/ENSGALP00010021035.1" } ] } }, { "isoform_ac": "R4GLB3-1", "url": "https://www.uniprot.org/uniprotkb/R4GLB3/entry", "sequence": { "sequence": "MEYLIGIQGPDYVLVAADTVAASSIVQMKHDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADYLRSRTPYHVNLLLAGYDDHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYKPGITREEAVELLKKCLEELQKRFVLNLTSFNARFIDKDGIHEVDSVPLLKALS", "length": 201, "header": "tr|R4GLB3-1|R4GLB3_CHICK Computationally mapped isoform of Proteasome subunit beta OS=Gallus gallus OX=9031 GN=PSMB2 PE=1 SV=1 CANONICAL=A0A8V0YQV8-1" }, "locus": { "chromosome": "23", "start_pos": 4640989, "end_pos": 4632820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036201.1", "url": "https://www.ensembl.org/id/ENSGALT00010036201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021043.1", "url": "https://www.ensembl.org/id/ENSGALP00010021043.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419630", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VZE2-1", "protein_name": "Proteasome subunit beta", "gene_name": "PSMB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDQVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISREKAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQGS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H9V0-1", "protein_name": "Proteasome subunit beta", "gene_name": "Psmb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERALELLRKCLDELQKRFILNLPTFSVRVIDKNGIHNLENITFSKKGS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O24633-1", "protein_name": "Proteasome subunit beta type-2-B", "gene_name": "PBD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MECVFGLVGNGFAIVAADTSAVHSILLHKNKEDKIMTLDSHKLVAASGEPGDRVQFTEYVQKNVSLYQFRNGIPLSTAAAANFTRGELATALRKNPYSVNILMAGYDKEAGASLYYIDYIATLHKVDKGAFGYGSYFSLSTMDRHYRSDMSVEEAIELVDKCILEIRSRLVIAPPNFVIKIVDKDGAREYGWRISTADA", "length": 199 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P22141-1", "protein_name": "Proteasome subunit beta type-4", "gene_name": "PRE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ", "length": 198 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40307-1", "protein_name": "Proteasome subunit beta type-2", "gene_name": "Psmb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRVIDKDGIHNLENITFTKRSS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49721-1", "protein_name": "Proteasome subunit beta type-2", "gene_name": "PSMB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQGS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55DY7-1", "protein_name": "Proteasome subunit beta type-2", "gene_name": "psmB2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METLLAFKVKGGVLCLADSSVNHSIVKMKDDEDKILEIDGHKLLLSAGEAGDRVQFTEYISKNIKLYSLRNSYPMSTPAAANFIRNELATSIRSHPYSINLILAGYDKEVEDGGTSLYYMDYLGSLQKLNFGCHGYASYFLLGLLDRHHKCDLSLEDGINLMHLCTTELKTRFLVSGKYTLKFVSSEGIKVLPFNAPQ", "length": 198 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5E9K0-1", "protein_name": "Proteasome subunit beta type-2", "gene_name": "PSMB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADYLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISREKAVELLRKCLEELQKRFILNLPTFSVRIIDRNGIHDLDNISFPKQGS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9R1P3-1", "protein_name": "Proteasome subunit beta type-2", "gene_name": "Psmb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRVIDKDGIHNLENIAFPKRDS", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJJ0-1", "protein_name": "Proteasome subunit beta", "gene_name": "Prosbeta4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METLLGIKGPDFVMLAADTTHARSIIVMKEDQNKIHKVSDSLLISTVGESGDTEQFTEFISKNIALYKMRNGYDLSPRESAHFTRKNLAEYLRSRTPYQVFMFVAGYDPNAGPELTFIDYLANALPVNYAGHGYGAIFASSIYDRYWHPNITQAEAYDVFKKCIAEIQKRLVVNLKNFTVAVVDKDGVRDLEPISAASLAA", "length": 201 }, "evidence": [ { "id": "A0A8V0YQV8", "url": "https://omabrowser.org/oma/group/A0A8V0YQV8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8" } ], "pmid": "" }, { "name": "proteasome core complex", "id": "GO:0005839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV8" 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140398" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NT70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC395611", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70", "locus": {} } ], "crossref": [ { "id": "A0A1D5NT70", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NT70", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038652", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03208", 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Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395611", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYLNIDY", "url": "https://omabrowser.org/oma/group/AYLNIDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NT70", "url": "https://www.orthodb.org/?gene=A0A1D5NT70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9748787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015140398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140398", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NT70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NT70-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGKPVLHYANIRGRMEPIRWLLAAAGVEFEERILKTKDDLQKLRTDGFLLFQQVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVEGLADLNELILHHEFKPANEMEKDLANILDKATNRYLPVFEKVLKDHGHDFLVGNKLSKADVHLLENILWLEELKPDVLAKFPLLQSFKARMSNMPNIKKFLQPGSPKKPIVQEKDVPAVLAIFS", "length": 221, "header": "tr|A0A1D5NT70-1|A0A1D5NT70_CHICK Isoform 1 of glutathione transferase OS=Gallus gallus OX=9031 GN=LOC395611 PE=1 SV=1 CANONICAL=A0A1D5NT70-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NT70-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70/entry", "sequence": { "sequence": "MSGKPVLHYANIRGRMEPIRWLLAAAGVEFEERILKTKDDLQKLRTDGFLLFQQVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVEGLADLNELILHHEFKPANEMEKDLANILDKATNRYLPVFEKVLKDHGHDFLVGNKLSKADVHLLENILWLEELKPDVLAKFPLLQSFKARMSNMPNIKKFLQPGSPKKPIVQEKDVPAVLAIFS", "length": 221, "header": "tr|A0A1D5NT70-1|A0A1D5NT70_CHICK Isoform 1 of glutathione transferase OS=Gallus gallus OX=9031 GN=LOC395611 PE=1 SV=1 CANONICAL=A0A1D5NT70-1" }, "locus": { "chromosome": "3", "start_pos": 88102843, "end_pos": 88098783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006466.1", "url": "https://www.ensembl.org/id/ENSGALT00010006466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003985.1", "url": "https://www.ensembl.org/id/ENSGALP00010003985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395611", "resource": "KEGG Pathway" }, { "id": "R-GGA-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-GGA-9748787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748787", "resource": "Reactome", "description": "Azathioprine ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AXU5-1", "protein_name": "Glutathione S-transferase", "gene_name": "LOC100526118", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGKPKLHYFDGRGRAEVIRWLLASAGVEFEEKFVDTLEDLEKLRNDGSLMFQQVPMIEIDGMKLVQTRAILNYIATKYDLCGKDIKERAAVDMYTEGIADIGEMIMLLPICPPDEKDAKMALIKERVSNHYLPAFEKVLKSHGQDYLVGNKLSRADIQLVELLYYVEELDPSLLANFPLLKALKTRVSNLPTVKKFLQPGSQRKPPTDEESLEKARRIFKFK", "length": 223 }, "evidence": [ { "id": "A0A1D5NT70", "url": "https://omabrowser.org/oma/group/A0A1D5NT70/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O18879-1", "protein_name": "Glutathione S-transferase A2", "gene_name": "GSTA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGKPKLHYFNGRGRMECIRWLLAAAGVEFEEKFIEQPEDLDKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIATKYNLYGKDMKERALIDMYSEGVEDLGEMIMHLPLCPPDQKDAKIAQIKERTTNRYFPAFEKVLKNHGQDYLVGNKLSKADIHLVELLYYVEELDPSLLANFPLLKGLKARVSSLPAVKKFLQPGSQRKPPMDEKNLEEAKRIFRIK", "length": 223 }, "evidence": [ { "id": "A0A1D5NT70", "url": "https://omabrowser.org/oma/group/A0A1D5NT70/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P08263-1", "protein_name": "Glutathione S-transferase A1", "gene_name": "GSTA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF", "length": 222 }, "evidence": [ { "id": "A0A1D5NT70", "url": "https://omabrowser.org/oma/group/A0A1D5NT70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13745-1", "protein_name": "Glutathione S-transferase A1", "gene_name": "Gsta1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKIQ", "length": 223 }, "evidence": [ { "id": "A0A1D5NT70", "url": "https://omabrowser.org/oma/group/A0A1D5NT70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54VI4-1", "protein_name": "Putative glutathione S-transferase alpha-3", "gene_name": "gsta3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKPQLSYFKVRALGQFPRVLLSYLSIDYDNNYIDKIDENIIDDLKYGQLPLYTDSNGFKLVQSMAISKYIASQHDFVGKTPEEKALVDETLAAVNIDVFTFIIRVFRGVEEKEKIQEIIIPRFFAKWNQILGEKKYLAGGNSYTLADLYVYVAYEYIGYVLPFAADLLYNGKFPHLDSLKEHFESNKGVAEYLKNRPITERKI", "length": 204 }, "evidence": [ { "id": "A0A1D5NT70", "url": "https://omabrowser.org/oma/group/A0A1D5NT70/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NT70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NT70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NT70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20135-1", "Q08393-1", "A0A8V1AI83-1", "A0A8V0ZJE0-1", "A0A8V0XB81-1", "A0A1D5PN41-1", "A0A8V0XH39-1", "E1BUB6-1", "O73888-1", "A0A1D5NT70-1" ], "evidence": [ { "id": "R-GGA-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176054" } ] }, { "id": "R-GGA-9748996", "name": "GST dimers cleave AZA to 6MP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9748994" ], "output_participant_list": [ "R-ALL-9748975" ], "enzyme_list": [ "Q08393-1", "A0A8V0XB81-1", "A0A8V0XH39-1", "A0A1D5NT70-1" ], "evidence": [ { "id": "R-GGA-9748996", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748996" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9748975", "participant_name": "GS-nitroimidazole [cytosol]", "crossref": [ { "id": "180931", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9748994", "participant_name": "AZA [cytosol]", "crossref": [ { "id": "7120", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "2948", "database": "ChEBI", "url": "" }, { "id": "PDBC00620", "database": "PharmacoDB", "url": "" }, { "id": "0005101", "database": "Mondo", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NT70", "gene_name": "LOC395611", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] } ] }, { "uniprot_ac": "A0A1D5PN41", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] } ] }, { "uniprot_ac": "A0A8V0XB81", "gene_name": "GSTA4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] } ] }, { "uniprot_ac": "A0A8V0XH39", "gene_name": "LOC100859645", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] } ] }, { "uniprot_ac": "A0A8V0ZJE0", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] } ] }, { "uniprot_ac": "A0A8V1AI83", "gene_name": "LOC107050492", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] } ] }, { "uniprot_ac": "E1BUB6", "gene_name": "GSTT1L", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] } ] }, { "uniprot_ac": "O73888", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { 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"url": "https://www.uniprot.org/uniprotkb/Q08393" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q08393", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08393" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NT70-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 221, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NT70-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NT70" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.18", "ec_name": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "2.5.1.18", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18" }, { "id": "2.5.1.18", "database": "BRENDA Enzymes", "url": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NTI9-1", "uniprot_ac": "A0A1D5NTI9", "uniprot_id": "A0A1D5NTI9_CHICK", "mass": { "chemical_mass": 10356.0, "monoisotopic_mass": 10356.0 }, "refseq": { "ac": "NP_001289123", "name": "placenta-specific protein 9 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289123" }, "gene_names": [ { "name": "PLAC9", "type": "recommended", "evidence": [ { "id": "A0A1D5NTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTI9" } ] }, { "name": "PLAC9L", "type": "synonym", "evidence": 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The reference sequence was derived from JAENSK010000227.1. On Sep 23, 2021 this sequence version replaced NP_001289123.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTI9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLAC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTI9", "locus": { "chromosome": "6", "start_pos": 5836991, "end_pos": 5826705, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008918", "url": "https://www.ensembl.org/id/ENSGALG00010008918" } ] } } ], "crossref": [ { "id": "A0A1D5NTI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NTI9", "database": "AlphaFoldDB", 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"PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEPQLLGLCRVPPPRRANPGRAKNPQQLRCRQRWGPGMTPGPPPPPPSHPSRQFLWFLPGRLRLRDCYWFSGLIRVLIASAVAQPDCPNMAEASFGSSSPVGSLSSEDHDFDPSAEMLVHDYDDEQTLEEEEMMEDNKNFSSEIEDLEKEGNMPLEDLLAFYGYEPTIPVMAGSSADSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHEATDFFPRPLRSNTTCDGDKESDGEDVEVDSGNTSEDLRKEIMVGSKYQAEIPPYLGKCTDDEKAYENEDHLLWNPDVISENKVKEYLFESYVRTGNLKMIGRIPEGLQTRDNEQALYELLKSSHNVKEAIERYCSNGKASQEEMTAWTEEECRSFEHALLIYGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDHLVDEAEALGGAVHSSALTSNSRTETIPDQQLSILNSITANELTALTNSVTAVCHTSDANCLDDAFSPVDSLPRAAVNHVPVETEELLNLPSNGESDCFNLFETGFYHSELNPMNMCSEETERSAKRLKMGIAVPESFMNDVSVNNLGVDFENHTHITTAKMAVSVADFSSLSTNDANGFINTHTLHQHTALHSE", "length": 640, "header": "tr|A0A1D5NTJ6-1|A0A1D5NTJ6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC426615 PE=4 SV=1 CANONICAL=A0A1D5NTJ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6/entry", "sequence": { "sequence": "MKEPQLLGLCRVPPPRRANPGRAKNPQQLRCRQRWGPGMTPGPPPPPPSHPSRQFLWFLPGRLRLRDCYWFSGLIRVLIASAVAQPDCPNMAEASFGSSSPVGSLSSEDHDFDPSAEMLVHDYDDEQTLEEEEMMEDNKNFSSEIEDLEKEGNMPLEDLLAFYGYEPTIPVMAGSSADSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHEATDFFPRPLRSNTTCDGDKESDGEDVEVDSGNTSEDLRKEIMVGSKYQAEIPPYLGKCTDDEKAYENEDHLLWNPDVISENKVKEYLFESYVRTGNLKMIGRIPEGLQTRDNEQALYELLKSSHNVKEAIERYCSNGKASQEEMTAWTEEECRSFEHALLIYGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDHLVDEAEALGGAVHSSALTSNSRTETIPDQQLSILNSITANELTALTNSVTAVCHTSDANCLDDAFSPVDSLPRAAVNHVPVETEELLNLPSNGESDCFNLFETGFYHSELNPMNMCSEETERSAKRLKMGIAVPESFMNDVSVNNLGVDFENHTHITTAKMAVSVADFSSLSTNDANGFINTHTLHQHTALHSE", "length": 640, "header": "tr|A0A1D5NTJ6-1|A0A1D5NTJ6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC426615 PE=4 SV=1 CANONICAL=A0A1D5NTJ6-1" }, "locus": { "chromosome": "W", "start_pos": 4927363, "end_pos": 4778343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029531.1", "url": "https://www.ensembl.org/id/ENSGALT00010029531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017165.1", "url": "https://www.ensembl.org/id/ENSGALP00010017165.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NTJ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 640, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NTJ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NTJ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 598, "end_pos": 600 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NTR1-1", "uniprot_ac": "A0A1D5NTR1", "uniprot_id": "A0A1D5NTR1_CHICK", "mass": { "chemical_mass": 53298.0, "monoisotopic_mass": 53298.0 }, "refseq": { "ac": "NP_001026392", "name": "coiled-coil domain-containing protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392" }, "gene_names": [ { "name": "CCDC6", "type": "recommended", "evidence": [ { "id": "A0A1D5NTR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1" } ] }, { "name": "CCDC6", "type": "synonym", "evidence": [ { "id": "NP_001026392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 6", "type": "synonym", "evidence": [ { "id": "A0A1D5NTR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "NP_001026392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851457.1, HAEK01051086.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000227.1. On Sep 23, 2021 this sequence version replaced NP_001026392.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTR1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1", "locus": { "chromosome": "6", "start_pos": 9821206, "end_pos": 9760028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008656", "url": "https://www.ensembl.org/id/ENSGALG00010008656" } ] } } ], "crossref": [ { "id": "A0A1D5NTR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NTR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003165", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003165", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423666", "url": "https://www.ncbi.nlm.nih.gov/gene/423666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTQQEHN", "url": "https://omabrowser.org/oma/group/DTQQEHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NTR1", "url": "https://www.orthodb.org/?gene=A0A1D5NTR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7A1", "url": "https://www.orthodb.org/?gene=A0A8V0Y7A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15276:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15276:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NTR1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADSASESDTDGAGGSGGGGSAAGALAAGGPAAAGPGGGGGGSGSAGGGKAGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGPSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPVQPTVQSAASQSATFQHSVHPSSQP", "length": 478, "header": "tr|A0A1D5NTR1-1|A0A1D5NTR1_CHICK Isoform 1 of Coiled-coil domain containing 6 OS=Gallus gallus OX=9031 GN=CCDC6 PE=1 SV=1 CANONICAL=A0A1D5NTR1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1/entry", "sequence": { "sequence": "MADSASESDTDGAGGSGGGGSAAGALAAGGPAAAGPGGGGGGSGSAGGGKAGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGPSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPVQPTVQSAASQSATFQHSVHPSSQP", "length": 478, "header": "tr|A0A1D5NTR1-1|A0A1D5NTR1_CHICK Isoform 1 of Coiled-coil domain containing 6 OS=Gallus gallus OX=9031 GN=CCDC6 PE=1 SV=1 CANONICAL=A0A1D5NTR1-1" }, "locus": { "chromosome": "6", "start_pos": 9802580, "end_pos": 9760136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020532.1", "url": "https://www.ensembl.org/id/ENSGALT00010020532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011893.1", "url": "https://www.ensembl.org/id/ENSGALP00010011893.1" } ] } }, { "isoform_ac": "A0A8V0Y7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A1/entry", "sequence": { "sequence": "MADSASESDTDGAGGSGGGGSAAGALAAGGPAAAGPGGGGGGSGSAGGGKAGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGPSHGITWMTRGLVFVMENKKVDVV", "length": 433, "header": "tr|A0A8V0Y7A1-1|A0A1D5NTR1_CHICK Computationally mapped isoform of Coiled-coil domain containing 6 OS=Gallus gallus OX=9031 GN=CCDC6 PE=1 SV=1 CANONICAL=A0A1D5NTR1-1" }, "locus": { "chromosome": "6", "start_pos": 9820319, "end_pos": 9760136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020536.1", "url": "https://www.ensembl.org/id/ENSGALT00010020536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011897.1", "url": "https://www.ensembl.org/id/ENSGALP00010011897.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423666", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YZP9-1", "protein_name": "Coiled-coil domain-containing protein 6", "gene_name": "Ccdc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSASESDTDAAGGGPAAMQSSCSATSGGSGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGASHGITRPSPRRSSSPDKFKRPTPPPSPNTQSPVQPPPPPPPPPMQPAVPSAAPTQPAPTQPQHPVHPSSQP", "length": 469 }, "evidence": [ { "id": "A0A1D5NTR1", "url": "https://omabrowser.org/oma/group/A0A1D5NTR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AEK9-1", "protein_name": "Coiled-coil domain containing 6", "gene_name": "Ccdc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSASESDTDAAGGGPAAMQSSCSATSGGSGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGTSYYNSPGLHVQHMGASHGITRPSPRRSSSPDKFKRPTPPPSPNTQSPVQPPPPPPPPPMQPAVPSAATTTQPAPSQAQHPVHPSSQP", "length": 470 }, "evidence": [ { "id": "A0A1D5NTR1", "url": "https://omabrowser.org/oma/group/A0A1D5NTR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N091-1", "protein_name": "Coiled-coil domain containing 6", "gene_name": "CCDC6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADSASESDTDGAGGNSGSSAAMQSSCSSTSGGGGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGASHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPAVPSAATSQPAPSQHSVHPSSQP", "length": 477 }, "evidence": [ { "id": "A0A1D5NTR1", "url": "https://omabrowser.org/oma/group/A0A1D5NTR1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q16204-1", "protein_name": "Coiled-coil domain-containing protein 6", "gene_name": "CCDC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP", "length": 474 }, "evidence": [ { "id": "A0A1D5NTR1", "url": "https://omabrowser.org/oma/group/A0A1D5NTR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VVC8-1", "protein_name": "Coiled-coil domain-containing protein 6", "gene_name": "Ccdc6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESPCESESSLDGGTMLPPSPVSREQLQKRIESLTQQNKVLKAELDTFKTKCKVVQEENRCLKQASVIIQAKAEQEEEYISNTLLKKIQALKKEKETLAHHYEREEECLTNDLSRKLDQLRQEKCKLEQTLEQEQECLVNKLMRKIEKLQAETDNKQTNLEQLRREMVELENTLEQEQEALVNKLWKRMDKLETEKRSLQIKLDQPVSDPTTPRDITNNAHANGGDTATSLSAHIQILRSEVLRYRSDLASAQKEATIKTQQYAQEEKSIREENARLQRKLKQEVERREALCRHLSESESSLEMDEERFYNENLMGGGSFAVATAAAAAAASAVSAQRQRTISSPVSHSPSSSRPLSPGTAVQNRCYACGQLVNRRASERFIKPALPTPMLGLNTSAPNVLTSTNPLLGILGTGSSSSSASVSAGNAAGGFLSNLGGERLSLGSSNSAGGSATFLAGGGGGGLLAQLTSHSSASSSSSNLMNISLNNSSSGNLVNSSSNSSLSAFTPTNPPSSAATAFIQPASPMDTSTCKD", "length": 532 }, "evidence": [ { "id": "A0A1D5NTR1", "url": "https://omabrowser.org/oma/group/A0A1D5NTR1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTR1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NTR1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NTR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 478, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NTR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NTR1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 457 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NU20-1", "uniprot_ac": "A0A1D5NU20", "uniprot_id": "A0A1D5NU20_CHICK", "mass": { "chemical_mass": 74150.0, "monoisotopic_mass": 74150.0 }, "refseq": { "ac": "XP_015153999", "name": "small conductance calcium-activated potassium channel protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999" }, "gene_names": [ { "name": "KCNN3", "type": "recommended", "evidence": [ { "id": "A0A1D5NU20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ] }, { "name": "KCNN3", "type": "synonym", "evidence": [ { "id": "XP_015153999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999" } ] } ], "protein_names": [ { "name": "Potassium calcium-activated channel subfamily N member 3", "type": "synonym", "evidence": [ { "id": "A0A1D5NU20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20/entry#names_and_taxonomy" } ] }, { "name": "small conductance calcium-activated potassium channel protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015153999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20", "locus": { "chromosome": "25", "start_pos": 1985504, "end_pos": 2008434, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027534", "url": "https://www.ensembl.org/id/ENSGALG00010027534" } ] } } ], "crossref": [ { "id": "A0A1D5NU20", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU20", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030554", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030554", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100858107", "url": "https://www.ncbi.nlm.nih.gov/gene/100858107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858107", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858107", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VESFIFI", "url": "https://omabrowser.org/oma/group/VESFIFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NU20", "url": "https://www.orthodb.org/?gene=A0A1D5NU20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296052", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015153999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU20-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTSGHFHDSGVGDLEEDPRCPCPSSGDERPPPPPPPAALPPLQHSLLHSSPGSLRAPPPAAPAALHPSSRHGSQLNLSDHLGGHSPGSAVPSGGKHRQPSPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEAQPLQLFGAGGPPEIVVSREDNHAPPARPPTRHGPRADRPSARPAPAGFAKGPKRKAQNIGYRLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQLGSLEAKLEQLNASFNSLPLLLADMLRQQHQRLLAAVVEARAVAVPAGTPQTPLSESPIGVSSTSFPTPYTSSSSC", "length": 671, "header": "tr|A0A1D5NU20-1|A0A1D5NU20_CHICK Isoform 1 of Potassium calcium-activated channel subfamily N member 3 OS=Gallus gallus OX=9031 GN=KCNN3 PE=4 SV=2 CANONICAL=A0A1D5NU20-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU20-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20/entry", "sequence": { "sequence": "MDTSGHFHDSGVGDLEEDPRCPCPSSGDERPPPPPPPAALPPLQHSLLHSSPGSLRAPPPAAPAALHPSSRHGSQLNLSDHLGGHSPGSAVPSGGKHRQPSPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEAQPLQLFGAGGPPEIVVSREDNHAPPARPPTRHGPRADRPSARPAPAGFAKGPKRKAQNIGYRLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQLGSLEAKLEQLNASFNSLPLLLADMLRQQHQRLLAAVVEARAVAVPAGTPQTPLSESPIGVSSTSFPTPYTSSSSC", "length": 671, "header": "tr|A0A1D5NU20-1|A0A1D5NU20_CHICK Isoform 1 of Potassium calcium-activated channel subfamily N member 3 OS=Gallus gallus OX=9031 GN=KCNN3 PE=4 SV=2 CANONICAL=A0A1D5NU20-1" }, "locus": { "chromosome": "25", "start_pos": 2008394, "end_pos": 1987437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066690.1", "url": "https://www.ensembl.org/id/ENSGALT00010066690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040831.1", "url": "https://www.ensembl.org/id/ENSGALP00010040831.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858107", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858107", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "resource": "Reactome", "description": "Ca2+ activated K+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" }, { "name": "small conductance calcium-activated potassium channel activity", "id": "GO:0016286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016286", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" }, { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NU20-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 671, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NU20-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU20" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NU20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU20" }, { "id": "SM01053", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calmodulin-binding", "eco_id": "ECO_0000259", "start_pos": 501, "end_pos": 577, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 607, "end_pos": 609 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NU41-1", "uniprot_ac": "A0A1D5NU41", "uniprot_id": "A0A1D5NU41_CHICK", "mass": { "chemical_mass": 69144.0, "monoisotopic_mass": 69144.0 }, "refseq": { "ac": "XP_015136462", "name": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462" }, "gene_names": [ { "name": "GDPD5", "type": "recommended", "evidence": [ { "id": "A0A1D5NU41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ] }, { "name": "GDE2", "type": "synonym", "evidence": [ { "id": "XP_015136462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462" } ] }, { "name": "GDPD5", "type": "synonym", "evidence": [ { "id": "XP_015136462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462" } ] } ], "protein_names": [ { "name": "Glycerophosphodiester phosphodiesterase domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A1D5NU41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41/entry#names_and_taxonomy" } ] }, { "name": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015136462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015136462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GDPD5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41", "locus": { "chromosome": "1", "start_pos": 195567671, "end_pos": 195409382, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002946", "url": "https://www.ensembl.org/id/ENSGALG00010002946" } ] } } ], "crossref": [ { "id": "A0A1D5NU41", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU41", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034967", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034967", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08608", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08608", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419070", "url": "https://www.ncbi.nlm.nih.gov/gene/419070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HASMFNW", "url": "https://omabrowser.org/oma/group/HASMFNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NU41", "url": "https://www.orthodb.org/?gene=A0A1D5NU41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P988", "url": "https://www.orthodb.org/?gene=A0A1D5P988", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7U9", "url": "https://www.orthodb.org/?gene=A0A8V0X7U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7V9", "url": "https://www.orthodb.org/?gene=A0A8V0X7V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEV0", "url": "https://www.orthodb.org/?gene=A0A8V0XEV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23344:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23344:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015136462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P988", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P988", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P988-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P988-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7V9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQNYHMIRWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN", "length": 599, "header": "tr|A0A1D5NU41-1|A0A1D5NU41_CHICK Isoform 1 of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=2 CANONICAL=A0A1D5NU41-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41/entry", "sequence": { "sequence": "MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQNYHMIRWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN", "length": 599, "header": "tr|A0A1D5NU41-1|A0A1D5NU41_CHICK Isoform 1 of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=2 CANONICAL=A0A1D5NU41-1" }, "locus": { "chromosome": "1", "start_pos": 195565088, "end_pos": 195468287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006867.1", "url": "https://www.ensembl.org/id/ENSGALT00010006867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004186.1", "url": "https://www.ensembl.org/id/ENSGALP00010004186.1" } ] } }, { "isoform_ac": "A0A1D5P988-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P988/entry", "sequence": { "sequence": "MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMVALRKHQDLQPRADHAQRCRPPVQSGCQDHEGEADLLGDQQRRGDHRRAVPVL", "length": 544, "header": "tr|A0A1D5P988-1|A0A1D5P988_CHICK Computationally mapped isoform of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=2 CANONICAL=A0A1D5NU41-1" }, "locus": { "chromosome": "1", "start_pos": 195565021, "end_pos": 195468287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006885.1", "url": "https://www.ensembl.org/id/ENSGALT00010006885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004200.1", "url": "https://www.ensembl.org/id/ENSGALP00010004200.1" } ] } }, { "isoform_ac": "A0A8V0X7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U9/entry", "sequence": { "sequence": "MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQKKTWKQKPLGPCTQTWSREPGSRTSLRH", "length": 546, "header": "tr|A0A8V0X7U9-1|A0A1D5NU41_CHICK Computationally mapped isoform of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=1 CANONICAL=A0A1D5NU41-1" }, "locus": { "chromosome": "1", "start_pos": 195557420, "end_pos": 195468287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006863.1", "url": "https://www.ensembl.org/id/ENSGALT00010006863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004183.1", "url": "https://www.ensembl.org/id/ENSGALP00010004183.1" } ] } }, { "isoform_ac": "A0A8V0X7V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V9/entry", "sequence": { "sequence": "MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQVSCLWACFPRWACEVLLSITMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQKWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN", "length": 580, "header": "tr|A0A8V0X7V9-1|A0A1D5NU41_CHICK Computationally mapped isoform of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=1 CANONICAL=A0A1D5NU41-1" }, "locus": { "chromosome": "1", "start_pos": 195565088, "end_pos": 195468287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006876.1", "url": "https://www.ensembl.org/id/ENSGALT00010006876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004193.1", "url": "https://www.ensembl.org/id/ENSGALP00010004193.1" } ] } }, { "isoform_ac": "A0A8V0XEV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEV0/entry", "sequence": { "sequence": "MNPAIKDVGSKPGHREWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQKWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN", "length": 571, "header": "tr|A0A8V0XEV0-1|A0A1D5NU41_CHICK Computationally mapped isoform of Glycerophosphodiester phosphodiesterase domain containing 5 OS=Gallus gallus OX=9031 GN=GDPD5 PE=3 SV=1 CANONICAL=A0A1D5NU41-1" }, "locus": { "chromosome": "1", "start_pos": 195565088, "end_pos": 195517498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006860.1", "url": "https://www.ensembl.org/id/ENSGALT00010006860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004180.1", "url": "https://www.ensembl.org/id/ENSGALP00010004180.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B4R1-1", "protein_name": "Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "gene_name": "gdpd5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVKHQPLQVYERQLCLSCLTGIYGCRWKRYQRSHDDTTKWECLWSLILFFTFSLLLVWFYFWWEAHNDYSEFNWFLYNRSGEWSDGTVPILATTAAGFTYIAFLMILALCHVAVGQQLNLHWVHKIGVTVALLTTIIGVISVTQMWGEEWDVVWISLQATGPFLHIGALAAVTALAWLMAGQVARAEKTRFQAMVLLLYLSVLLTLYFIPLSISSPCIMERGSLKAAPAIIGHQGAPMLAPENTLLSFNRALQRNVSGLETDVTISLDGVPFLMRDRTLRRTTNVRRVFPERQYEDASLFNWTDLSTLNAGQWFLKDDPFWTVQYMSTTERWSVGNQTVCSLEQMLKLAAKYKSSALFTVHRPPVNHPHHHDWVNLTLDTVLGSGIPQGQVMWTVDSNREMVRKVAPGFQQTSMQKLPFDTLHHNGISRLLLRYNQASEQDVRLYKENNISVSLYTVNEPWLYSLLWCSGVPSVSSEAPQVLRKLHYPLWLMTPDEYCLIWISTDLISFAVVLGIFIFQNYHMIRWRMSGMRSYNPEQIMLSAAVRRSSRDVNIMKEKLIFSEVSNGVNGDEAYSENGFNYYTN", "length": 584 }, "evidence": [ { "id": "A0A1D5NU41", "url": "https://omabrowser.org/oma/group/A0A1D5NU41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V9L7-1", "protein_name": "Glycerophosphodiester phosphodiesterase domain containing 5", "gene_name": "Gdpd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLVCTFSLTLTWLYFWWGVHNDYDEFNWYLYNRMGYWSDWSVPILVTTAAAFTYIAGLLVLALCHIAVGQQMNLHWIHKMGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHIGALVAITALSWIVAGQFARAERSSSQLTILCTFFAVVFTFYLVPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEQVFPELARRPAAMLNWTSLQRLNAGQWFLKTDPFWTASSLSPSDHREVENQSICSLAELLELAKGNATLLLNLRDPPHDHPYRGSFLNITLEAVLRSGFPQHQVMWLFNRQRPLVRKMAPGFQQTSGSKEAIASLRRGHIQKLNLHYTQVSHQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHTLSRVPSPLWIMPPDEYCLMWVTADLISFSLIIGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDELSVCSDSSYDTYANSTVTPMGPQSAGSRAKTFTEQGGH", "length": 605 }, "evidence": [ { "id": "A0A1D5NU41", "url": "https://omabrowser.org/oma/group/A0A1D5NU41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q640M6-1", "protein_name": "Glycerophosphodiester phosphodiesterase 2", "gene_name": "Gdpd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLVCTFSLTLTWLYFWWGVHNDYDEFNWYLYNRMGYWSDWSVPILVTSAAAFTYIAGLLVLALCHIAVGQQLNLHWIHKMGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHIGALVAITALSWIVAGQFARAERSSSQLTILCTFFAVVFTFYLIPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTVMSFRKALEQRLYGLQADITISLDGVPFLMHDTTLRRTTNVEHLFPELARRPAAMLNWTVLQRLNAGQWFLKTDPFWTASSLSPSDHREVQNQSICSLAELLELAKGNASLLLNLRDPPRDHPYRGSFLNVTLEAVLRSGFPQHQVMWLFNRQRPLVRKMAPGFQQTSGSKEAIANLRKGHIQKLNLRYTQVSHQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHTLSRVPSPLWIMPPDEYCLMWVTADLISFSLIIGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDELSVCSDSSYDTYANANSTATPVGPRNAGSRAKTVTEQSGH", "length": 607 }, "evidence": [ { "id": "A0A1D5NU41", "url": "https://omabrowser.org/oma/group/A0A1D5NU41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WTR4-1", "protein_name": "Glycerophosphodiester phosphodiesterase 2", "gene_name": "GDPD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLTWLYFWWEVHNDYDEFNWYLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQMNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPASMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHALSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDVLSVCSDNSYDTYANSTATPVGPRGGGSHTKTLIERSGR", "length": 605 }, "evidence": [ { "id": "A0A1D5NU41", "url": "https://omabrowser.org/oma/group/A0A1D5NU41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glycerophosphodiester phosphodiesterase activity", "id": "GO:0008889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008889", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU41", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NU41-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 599, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NU41-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU41" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 301, "end_pos": 303 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 448, "end_pos": 450 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NU45-1", "uniprot_ac": "A0A1D5NU45", "uniprot_id": "A0A1D5NU45_CHICK", "mass": { "chemical_mass": 28658.0, "monoisotopic_mass": 28658.0 }, "refseq": { "ac": "NP_001264846", "name": "chymotrypsin-C precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846" }, "gene_names": [ { "name": "CTRC", "type": "recommended", "evidence": [ { "id": "A0A1D5NU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45" } ] }, { "name": "CTRC", "type": "synonym", "evidence": [ { "id": "NP_001264846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846" } ] } ], "protein_names": [ { "name": "Chymotrypsin C", "type": "synonym", "evidence": [ { "id": "A0A1D5NU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45/entry#names_and_taxonomy" } ] }, { "name": "chymotrypsin C (caldecrin)", "type": "synonym", "evidence": [ { "id": "NP_001264846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846" } ] }, { "name": "chymotrypsin-C precursor", "type": "synonym", "evidence": [ { "id": "NP_001264846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX935336.1, CR338978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000329.1. On Apr 28, 2013 this sequence version replaced XP_428223.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001264846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU45", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTRC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45", "locus": { "chromosome": "21", "start_pos": 4922829, "end_pos": 4924734, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020939", "url": "https://www.ensembl.org/id/ENSGALG00010020939" } ] } } ], "crossref": [ { "id": "A0A1D5NU45", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039406", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039406", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430670", "url": "https://www.ncbi.nlm.nih.gov/gene/430670", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430670", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430670", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWISSKM", "url": "https://omabrowser.org/oma/group/DWISSKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NU45", "url": "https://www.orthodb.org/?gene=A0A1D5NU45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24257:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24257:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NU45", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU45-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAVCLAILLGYAYGCGQPAVPPLLGARVVGGEDARAHSWPWQISLQYSRDGAWRHTCGGTLISPSWVLTAAHCISSSLTYRVVLGEHNLAVEDDGAVVAEVEKIVVHEKWNSFLIVNDIALIKLTEPVQESDTIQAACLPPSGLELENDYPCEITGWGRLWTNGPLAEVLQQALLPVVDYATCSQSDWWGGLVRTSMVCAGGDGVVSGCNGDSGGPLSCQRNGLWEVHGIVSFGSSWGCNTAKKPTVFTRVSAYIDWINEKISEN", "length": 267, "header": "tr|A0A1D5NU45-1|A0A1D5NU45_CHICK Isoform 1 of Chymotrypsin C OS=Gallus gallus OX=9031 GN=CTRC PE=4 SV=1 CANONICAL=A0A1D5NU45-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU45-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45/entry", "sequence": { "sequence": "MLGAVCLAILLGYAYGCGQPAVPPLLGARVVGGEDARAHSWPWQISLQYSRDGAWRHTCGGTLISPSWVLTAAHCISSSLTYRVVLGEHNLAVEDDGAVVAEVEKIVVHEKWNSFLIVNDIALIKLTEPVQESDTIQAACLPPSGLELENDYPCEITGWGRLWTNGPLAEVLQQALLPVVDYATCSQSDWWGGLVRTSMVCAGGDGVVSGCNGDSGGPLSCQRNGLWEVHGIVSFGSSWGCNTAKKPTVFTRVSAYIDWINEKISEN", "length": 267, "header": "tr|A0A1D5NU45-1|A0A1D5NU45_CHICK Isoform 1 of Chymotrypsin C OS=Gallus gallus OX=9031 GN=CTRC PE=4 SV=1 CANONICAL=A0A1D5NU45-1" }, "locus": { "chromosome": "21", "start_pos": 4924711, "end_pos": 4922886, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050595.1", "url": "https://www.ensembl.org/id/ENSGALT00010050595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029867.1", "url": "https://www.ensembl.org/id/ENSGALP00010029867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430670", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430670", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SUW2-1", "protein_name": "Chymotrypsin C", "gene_name": "CTRC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLGITVLAALLAYASSCGVPSFPPNLSARVVGGENAIPHSWPWQISLQYLSGDTWKHTCGGTLITSTHVLTAAHCISNSRTYRVALGKNNLEVEDEEGSLVVGVDSIFVHEKWNSLLIRNDIALIKLAEPVELSDTIQVSCLPEEGSLLPQDYPCYVTGWGRLWTNGPIAAELQQGLQPVVDHATCSQRDWWGSTVRDTMVCAGGDGVISACNGDSGGPLNCQAENGSWEVRGIVSFGSGLGCNTYKKPTVFTRVSAYIDWIDQKIQL", "length": 268 }, "evidence": [ { "id": "A0A1D5NU45", "url": "https://omabrowser.org/oma/group/A0A1D5NU45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P55091-1", "protein_name": "Chymotrypsin-C", "gene_name": "Ctrc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGITVLAAILACASCCGNPAFPPNLSTRVVGGEDAVPNSWPWQVSLQYLKDDTWRHTCGGSLITTSHVLTAAHCINKDFTYRVGLGKYNLTVEDEEGSVYAEVDTIYVHEKWNRLFLWNDIAIIKLAEPVELSNTIQVACIPEEGSLLPQDYPCYVTGWGRLWTNGPIAEVLQQGLQPIVSHATCSRLDWWFIKVRKTMVCAGGDGVISACNGDSGGPLNCQAEDGSWQVHGIVSFGSSSGCNVHKKPVVFTRVSAYNDWINEKIQL", "length": 268 }, "evidence": [ { "id": "A0A1D5NU45", "url": "https://omabrowser.org/oma/group/A0A1D5NU45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7M3E1-1", "protein_name": "Chymotrypsin-C", "gene_name": "CTRC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGITVFTTFLAYASSCGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELSDTIQVACLPEEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCAGGDGVISACNGDSGGPLNCQAENGNWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQKLQL", "length": 268 }, "evidence": [ { "id": "A0A1D5NU45", "url": "https://omabrowser.org/oma/group/A0A1D5NU45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99895-1", "protein_name": "Chymotrypsin-C", "gene_name": "CTRC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL", "length": 268 }, "evidence": [ { "id": "A0A1D5NU45", "url": "https://omabrowser.org/oma/group/A0A1D5NU45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU45", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU45", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NU45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 267, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NU45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU45" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 265, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NU91-1", "uniprot_ac": "A0A1D5NU91", "uniprot_id": "A0A1D5NU91_CHICK", "mass": { "chemical_mass": 87607.0, "monoisotopic_mass": 87607.0 }, "refseq": { "ac": "XP_015138722", "name": "solute carrier family 45 member 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722" }, "gene_names": [ { "name": "SLC45A4", "type": "recommended", "evidence": [ { "id": "A0A1D5NU91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ] }, { "name": "SLC45A4", "type": "synonym", "evidence": [ { "id": "XP_015138722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722" } ] } ], "protein_names": [ { "name": "Polyamine-transporter SLC45A4", "type": "recommended", "evidence": [ { "id": "A0A1D5NU91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 45 member 4", "type": "synonym", "evidence": [ { "id": "A0A1D5NU91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 45 member 4", "type": "synonym", "evidence": [ { "id": "XP_015138722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722" } ] }, { "annotation": "Neuronal polyamine-transporter involved in pain perception. Transports polyamines such as putrescine, cadaverine, spermine and spermidine. Expressed in sensory neuron subtypes within the dorsal root ganglion, where it regulates the excitability of C-polymodal nociceptors by mediating polyamine transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91#function" }, { "database": "UniProtKB", "id": "ARBA00094388", "url": "https://www.uniprot.org/uniprotkb/ARBA00094388#function" }, { "database": "UniProtKB", "id": "A0A8V0Y561", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y561#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC45A4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91", "locus": { "chromosome": "2", "start_pos": 144954963, "end_pos": 145015858, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009253", "url": "https://www.ensembl.org/id/ENSGALG00010009253" } ] } } ], "crossref": [ { "id": "A0A1D5NU91", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034971", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420308", "url": "https://www.ncbi.nlm.nih.gov/gene/420308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420308", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VPNINGS", "url": "https://omabrowser.org/oma/group/VPNINGS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NU91", "url": "https://www.orthodb.org/?gene=A0A1D5NU91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2W5", "url": "https://www.orthodb.org/?gene=A0A8V0Y2W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y561", "url": "https://www.orthodb.org/?gene=A0A8V0Y561", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138722", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "35039", "url": "https://www.rhea-db.org/rhea/35039", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72135", "url": "https://www.rhea-db.org/rhea/72135", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y561", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y561", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y561-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y561-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMKMAPQNADSESMQVQDLPVAQLQKPENKENESREETISEGSIDRIPIRLWVMHGAVMFGREFCYAMETALVTPVLLQIGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCIGVLFGVALFLNGSVIGLAIGDVPDKQPIGIVLTVLGVVVLDFCADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYMLGGLDWTQTFLGGIFKSQEQVLFFFAAIIFSVSVALHLFSIEEEQYNPQQDRIDEEGDTLSSVKFSGSLPPLNRLNVISEEEPYGASMFHDEVQSEHDLNMEFLEVNIVRSKSDSVLHMPDATLEIESELLFLHDIEPSIFQDASYPNTPHNTSQEIMKSKLNHLSAFLRDNEKEEEMLLDNHLNEDKVPNMNGSLPKEFLNGHARIGMKQSSTSNSMRRRRHMFYRQPSYTFSYYGKIGSHRYRFRRANAIVLIKSSRSMNDIYDMQKRQRQRYRHRNQSGTTNSSGDTESEEGETETTVRLLWLSMLKMPKELLRLCVCHLLTWFSIIAEAVFYTDFMGQVIFQGDPKAPSNSTELHAYNAGVQMGCWGLVIYAATAAVCSALLQKYLDNYDLSIKVIYILGTLGFSLGTAVMAIFPNVYVTMIMISTMGIVSMSISYCPYALLGQYHDIKEYIHHSPGNSKRGFGIDCAILSCQVYISQILVASALGSVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPEVNEEPKEEQKGLGPPETTEGNSTGAEKPTVLKLTRKGTTTSELEGESAV", "length": 787, "header": "tr|A0A1D5NU91-1|A0A1D5NU91_CHICK Isoform 1 of Polyamine-transporter SLC45A4 OS=Gallus gallus OX=9031 GN=SLC45A4 PE=3 SV=2 CANONICAL=A0A1D5NU91-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91/entry", "sequence": { "sequence": "MVMKMAPQNADSESMQVQDLPVAQLQKPENKENESREETISEGSIDRIPIRLWVMHGAVMFGREFCYAMETALVTPVLLQIGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCIGVLFGVALFLNGSVIGLAIGDVPDKQPIGIVLTVLGVVVLDFCADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYMLGGLDWTQTFLGGIFKSQEQVLFFFAAIIFSVSVALHLFSIEEEQYNPQQDRIDEEGDTLSSVKFSGSLPPLNRLNVISEEEPYGASMFHDEVQSEHDLNMEFLEVNIVRSKSDSVLHMPDATLEIESELLFLHDIEPSIFQDASYPNTPHNTSQEIMKSKLNHLSAFLRDNEKEEEMLLDNHLNEDKVPNMNGSLPKEFLNGHARIGMKQSSTSNSMRRRRHMFYRQPSYTFSYYGKIGSHRYRFRRANAIVLIKSSRSMNDIYDMQKRQRQRYRHRNQSGTTNSSGDTESEEGETETTVRLLWLSMLKMPKELLRLCVCHLLTWFSIIAEAVFYTDFMGQVIFQGDPKAPSNSTELHAYNAGVQMGCWGLVIYAATAAVCSALLQKYLDNYDLSIKVIYILGTLGFSLGTAVMAIFPNVYVTMIMISTMGIVSMSISYCPYALLGQYHDIKEYIHHSPGNSKRGFGIDCAILSCQVYISQILVASALGSVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPEVNEEPKEEQKGLGPPETTEGNSTGAEKPTVLKLTRKGTTTSELEGESAV", "length": 787, "header": "tr|A0A1D5NU91-1|A0A1D5NU91_CHICK Isoform 1 of Polyamine-transporter SLC45A4 OS=Gallus gallus OX=9031 GN=SLC45A4 PE=3 SV=2 CANONICAL=A0A1D5NU91-1" }, "locus": { "chromosome": "2", "start_pos": 144985833, "end_pos": 144956618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022073.1", "url": "https://www.ensembl.org/id/ENSGALT00010022073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012660.1", "url": "https://www.ensembl.org/id/ENSGALP00010012660.1" } ] } }, { "isoform_ac": "A0A8V0Y2W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2W5/entry", "sequence": { "sequence": "MVMKMAPQNADSESMQVQDLPVAQLQKPENKENESREETISEGSIDRIPIRLWVMHGAVMFGREFCYAMETALVTPVLLQIGLAIGDVPDKQPIGIVLTVLGVVVLDFCADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYMLGGLDWTQTFLGGIFKSQEQVLFFFAAIIFSVSVALHLFSIEEEQYNPQQDRIDEEGDTLSSVKFSGSLPPLNRLNVISEEEPYGASMFHDEVQSEHDLNMEFLEVNIVRSKSDSVLHMPDATLEIESELLFLHDIEPSIFQDASYPNTPHNTSQEIMKSKLNHLSAFLRDNEKEEEMLLDNHLNEDKVPNMNGSLPKEFLNGHARIGMKQSSTSNSMRRRRHMFYRQPSYTFSYYGKIGSHRYRFRRANAIVLIKSSRSMNDIYDMQKRQRQRYRHRNQSGTTNSSGDTESEEGETETTVRLLWLSMLKMPKELLRLCVCHLLTWFSIIAEAVFYTDFMGQVIFQGDPKAPSNSTELHAYNAGVQMGCWGLVIYAATAAVCSALLQKYLDNYDLSIKVIYILGTLGFSLGTAVMAIFPNVYVTMIMISTMGIVSMSISYCPYALLGQYHDIKEYIHHSPGNSKRGFGIDCAILSCQVYISQILVASALGSVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPEVNEEPKEEQKGLGPPETTEGNSTGAEKPTVLKLTRKGTTTSELEGESAV", "length": 724, "header": "tr|A0A8V0Y2W5-1|A0A1D5NU91_CHICK Computationally mapped isoform of Polyamine-transporter SLC45A4 OS=Gallus gallus OX=9031 GN=SLC45A4 PE=3 SV=1 CANONICAL=A0A1D5NU91-1" }, "locus": { "chromosome": "2", "start_pos": 144985833, "end_pos": 144956618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022072.1", "url": "https://www.ensembl.org/id/ENSGALT00010022072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012659.1", "url": "https://www.ensembl.org/id/ENSGALP00010012659.1" } ] } }, { "isoform_ac": "A0A8V0Y561-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y561/entry", "sequence": { "sequence": "MPSFFLVSGCTDQMLCWVRCTPVTCLAASTRTFLVSQDLESQLGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCIGVLFGVALFLNGSVIGLAIGDVPDKQPIGIVLTVLGVVVLDFCADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYMLGGLDWTQTFLGGIFKSQEQVLFFFAAIIFSVSVALHLFSIEEEQYNPQQDRIDEEGDTLSSVKFSGSLPPLNRLNVISEEEPYGASMFHDEVQSEHDLNMEFLEVNIVRSKSDSVLHMPDATLEIESELLFLHDIEPSIFQDASYPNTPHNTSQEIMKSKLNHLSAFLRDNEKEEEMLLDNHLNEDKVPNMNGSLPKEFLNGHARIGMKQSSTSNSMRRRRHMFYRQPSYTFSYYGKIGSHRYRFRRANAIVLIKSSRSMNDIYDMQKRQRQRYRHRNQSGTTNSSGDTESEEGETETTVRLLWLSMLKMPKELLRLCVCHLLTWFSIIAEAVFYTDFMGQVIFQGDPKAPSNSTELHAYNAGVQMGCWGLVIYAATAAVCSALLQKYLDNYDLSIKVIYILGTLGFSLGTAVMAIFPNVYVTMIMISTMGIVSMSISYCPYALLGQYHDIKEYIHHSPGNSKRGFGIDCAILSCQVYISQILVASALGSVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPEVNEEPKEEQKGLGPPETTEGNSTGAEKPTVLKLTRKGTTTSELEGESAV", "length": 749, "header": "tr|A0A8V0Y561-1|A0A1D5NU91_CHICK Computationally mapped isoform of Polyamine-transporter SLC45A4 OS=Gallus gallus OX=9031 GN=SLC45A4 PE=3 SV=1 CANONICAL=A0A1D5NU91-1" }, "locus": { "chromosome": "2", "start_pos": 144974167, "end_pos": 144956618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022056.1", "url": "https://www.ensembl.org/id/ENSGALT00010022056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012650.1", "url": "https://www.ensembl.org/id/ENSGALP00010012650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420308", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADC6-1", "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "Slc45a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMAPQNADSESMQVQELPVPLPDPQKPRDPAAETQEETTSEASIDRIPTRLWVMHGAVMFGREFCYAMETALVTPILLQIGLPEKYYSLTWFLSPVLGLIFTPLIGSASDRCTLSWGRRRPFILVLCVGVLIGVALFLNGSAIGLALGDVPSRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGKDPCQAPGLGGAIGYVLGGLDWTQTFLGDWFQTQNQVLFFFAAVFFSVSVALHLFSIEEEQYNPQQDRGPEDATLPSTGLQPGAPAPAPRLSSLGGGMQDGSPPFPDEVQSEHELSLDYLDVDIVRSKSDSVLHMADSTLDMEPQLLFLHDIEPSIFQDASYPSTPQSTSQELLRAKLPRLSTFLRESTKEDDTLLDNHLNEAKVPNGRGSPPMNPLSHSKVDLKPSVTSSSMRRRRHMFHRQSSSTFSYYGKIGSHCYRYRRANAVVLIKPSRSMSDLYDLQQRQRSRHRNQSGATASSGDTESEEGETETTVRLLWLSMLKMPKELMWLCLCHLLTWFSVIAEAVFYTDFMGQVIFKGNPQAPSNSTKWHAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSIRIIYMLGTLGFSVGTAVMAMFPNVYVAMVTISTMGVVSMSISYCPYALLGHYHDIKEYVHHSPGNSKRGFGIDCAILSCQVYISQILVASALGGVVDTVNTIVVIPIVASVGSFLGFLTATFLVIYPEVSEEAKEEQKGLSSGAAGEGESGAGTEKPTVLKLSRKGGLRGLMETESMV", "length": 793 }, "evidence": [ { "id": "A0A1D5NU91", "url": "https://omabrowser.org/oma/group/A0A1D5NU91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGZ7-1", "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "SLC45A4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKMAPQNADAESMQVQELPVPLPDLQKPGRAEAETRDETVSEGSIDRIPVRLWVMHGAVMFGREFCYAMETALVTPVLLQIGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGVALFLNGSAIGLALGDVPTRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIIFTVSVALHLSSIEEEQYSPQQERGGDPASAPASGPRACVLDGSVLFPDEVQSEHELALDFLDEGLVRSKSDSVLHVPEAALGLEPELFLQDIEPSIFHDASCPSTPRSTSQEHAPARPPRRPLPLRAPAGEDETLLEEPLSAARLPNGGSAGLRDGPGTCAYSRAALKAPATAGPARRRRHVFRRQASSTFSYYGKIGSHRYRHRRANAVVLIKPSRSMSDLYDLQARPRQHRRRHQSGATTSSGDSESEEGEGETTVRLLWLSMLKMPPELVRLCLCHLLTWFSVIAEAVFYTDFMGQVIFEGDPKAPSNSTAWQAYSAGVKMGCWGLVIYAATGATCSALLQKYLDSYDLSIRVVYVLGTLGFSLGTAVMAMFANVYVAMIMISTMGVVSMSISYCPYALLGQYHDIREYVHHSPGTSKRGFGIDCAILSCQVYISQILVASALGSVVDAVGTVRVIPMVASVGSFLGFLTAAFLVIYPEVSEEAKEEQKGLSSQPLGEGASSSAEKPTMLKLSRKEAPQGLVETESMVFGRSVRSRHILLVLQLLESIFLYDYFRKKNFCLYFPKLWFS", "length": 814 }, "evidence": [ { "id": "A0A1D5NU91", "url": "https://omabrowser.org/oma/group/A0A1D5NU91/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RSK5-1", "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "SLC45A4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKMAPQNADAESMQVQELPVALPDLKPGGSEAEPRDETISEGSIDRIPVRLWVMHGAVMFGREFCYAMETALVTPILLQIGLPEQYYSLTWFLSPVLGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGAALFLNGSAIGLSLGDVPNRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIVFTVSVALHLLSIEEEQYSPQQERSVEAADALAPGLRASVLDGGPLFPDEVQSEHELALDYLDAGLARSKSDSVLHVPDAALDLEPELLFLRDIEPSIFQDASYPSTPRSTSQELARARPPRLPPLRREPAGEDETLLENHLDAAQLPNGGGSPPCDGLVGFSRADVKPPVASGSVRRRRHMFRRQASSTFSYYGKIGSHRYRYRRANAVVLIKPSRSMSDLYDLQKRQRQRCRRRNQSGATTSSGDTESEEGEGETTVRLLWLSMLKMPKELVRLCLCHLLTWFSVIAEAVFYTDFMGQVIFEGDPKAPSNSTAWQAYNSGVKMGCWGLVIYAATGATCSALLQKYLDNYDLSIRVIYVLGTLGFSLGTAVMAMFANVYVAMVMISTMGVVSMSISYCPYALLGQYHDIKEYVQHSPGSSRRGFGIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPEVSEEAKEEQKGLSSQPLGEGGSGGGEKPTVLRLSRKEGPQGPVETESMV", "length": 772 }, "evidence": [ { "id": "A0A1D5NU91", "url": "https://omabrowser.org/oma/group/A0A1D5NU91/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0P5V9-1", "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "Slc45a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAPQNADSESMQVQELPVPLPDPQKPRDPEAETQEETTSEGSIDRIPTRLWVMHGAVMFGREFCYAMETALVTPILLQIGLPEKYYSLTWFLSPVLGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLIGVALFLNGSAIGLALGDVPSRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGDWFQTQNQVLFFFAAVIFSVSVALHLFSIEEEQYSPQQDRGPEDPTLPGTSVQPGAPAPASRLSSLGGGMQDGSPPFPDEVQSEHELSLDYLDVDIVRSKSDSVLHMADATLDMEPQLLFLHDIEPSIFQDASYPSTPQSTSQELLRAKLPRLSTFLRESTKEDDTLLDNHLNEAKVPNGRGSPPINSLSRSKVDLKPSVTSGSMRRRRHMFHRQASSTFSYYGKIGSHCYRYRRANAVVLIKPSRSMSDLYDLQQRQRSRHRNQSGATASSGDTESEEGETETTVRLLWLSMLKMPKELMWLCLCHLLTWFSVIAEAVFYTDFMGQVIFKGNPQAPSNSTKWHAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSIRIIYMLGTLGFSVGTAVMAMFPNVYVAMVTISTMGVVSMSISYCPYALLGHYHDIKEYVHHSPGNSKRGFGIDCAILSCQVYISQILVASALGGVVDAVNSIVVIPIVASVGSFLGFLTATFLVIYPEVSEEPKEEQKGLSSGPAGEGEGGAGSEKPTVLKLSRKGGLRGLVETESMV", "length": 785 }, "evidence": [ { "id": "A0A1D5NU91", "url": "https://omabrowser.org/oma/group/A0A1D5NU91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BKX6-1", "protein_name": "Polyamine-transporter SLC45A4", "gene_name": "SLC45A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMAPQNADPESMQVQELSVPLPDPQKAGGAEAENCETISEGSIDRIPMRLWVMHGAVMFGREFCYAMETALVTPILLQIGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGVALFLNGSAIGLALGDVPNRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIIFTVSVALHLFSIDEEQYSPQQERSAEEPGALDGGEPHGVPAFPDEVQSEHELALDYPDVDIMRSKSDSALHVPDTALDLEPELLFLHDIEPSIFHDASYPATPRSTSQELAKTKLPRLATFLKEAAKEDETLLDNHLNEAKVPNGSGSPTKDALGGYTRVDTKPSATSSSMRRRRHAFRRQASSTFSYYGKLGSHCYRYRRANAVVLIKPSRSMSDLYDMQKRQRQHRHRNQSGATTSSGDTESEEGEGETTVRLLWLSMLKMPRELMRLCLCHLLTWFSVIAEAVFYTDFMGQVIFEGDPKAPSNSTAWQAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSVRVIYVLGTLGFSVGTAVMAMFPNVYVAMVTISTMGIVSMSISYCPYALLGQYHDIKQYIHHSPGNSKRGFGIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFLVIYPNVSEEAKEEQKGLSSPLAGEGRAGGNSEKPTVLKLTRKEGLQGPVETESVV", "length": 768 }, "evidence": [ { "id": "A0A1D5NU91", "url": "https://omabrowser.org/oma/group/A0A1D5NU91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" }, { "name": "behavioral response to pain", "id": "GO:0048266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048266", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "sucrose:proton symporter activity", "id": "GO:0008506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008506", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" }, { "name": "polyamine transmembrane transporter activity", "id": "GO:0015203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015203", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" }, { "name": "carbohydrate:proton symporter activity", "id": "GO:0005351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NU91", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "35039", "name": "", "equation": "spermidine(in) = spermidine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35039", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35039" } ] }, { "id": "72135", "name": "", "equation": "putrescine(out) = putrescine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72135" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NU91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 787, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NU91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NU91" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 406, 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Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004938360.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938360" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CGGBP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1", "locus": { "chromosome": "1", "start_pos": 88987423, "end_pos": 88999815, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006205", "url": "https://www.ensembl.org/id/ENSGALG00010006205" } ] } } ], "crossref": [ { "id": "ENSGALG00000015400", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015400", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770224", "url": "https://www.ncbi.nlm.nih.gov/gene/770224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770224", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKLYCTF", "url": "https://omabrowser.org/oma/group/GKLYCTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUG1", "url": "https://www.orthodb.org/?gene=A0A1D5NUG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32344:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32344:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004938360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFGVKSTPSRNRSKTALYVTPQDRVTEFGSELHEDGGKLFCTSCNVVLNHVRKSAINDHLKSKTHTKRKAEFEEQNVRKKQRTLTASLQCNSTAQTEKTSVIQDFVKMCLEANIPLEKADHPSVRAFLSRYVKNGSSIPKSEQLRKAYLPDGYDNENQLINTEDR", "length": 167, "header": "tr|A0A1D5NUG1-1|A0A1D5NUG1_CHICK Isoform 1 of CGG triplet repeat binding protein 1 OS=Gallus gallus OX=9031 GN=CGGBP1 PE=4 SV=1 CANONICAL=A0A1D5NUG1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1/entry", "sequence": { "sequence": "MERFGVKSTPSRNRSKTALYVTPQDRVTEFGSELHEDGGKLFCTSCNVVLNHVRKSAINDHLKSKTHTKRKAEFEEQNVRKKQRTLTASLQCNSTAQTEKTSVIQDFVKMCLEANIPLEKADHPSVRAFLSRYVKNGSSIPKSEQLRKAYLPDGYDNENQLINTEDR", "length": 167, "header": "tr|A0A1D5NUG1-1|A0A1D5NUG1_CHICK Isoform 1 of CGG triplet repeat binding protein 1 OS=Gallus gallus OX=9031 GN=CGGBP1 PE=4 SV=1 CANONICAL=A0A1D5NUG1-1" }, "locus": { "chromosome": "1", "start_pos": 88997039, "end_pos": 88996539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014775.1", "url": "https://www.ensembl.org/id/ENSGALT00010014775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008712.1", "url": "https://www.ensembl.org/id/ENSGALP00010008712.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770224", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ARL7-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "CGGBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADB4-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "Cggbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GYF2-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "Cggbp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MZ52-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "CGGBP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHG9-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "Cggbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSPAQTEKASVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLSSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UFW8-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "CGGBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "A0A1D5NUG1", "url": "https://omabrowser.org/oma/group/A0A1D5NUG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 13, "end_pos": 15 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUJ8-1", "uniprot_ac": "A0A1D5NUJ8", "uniprot_id": "A0A1D5NUJ8_CHICK", "mass": { "chemical_mass": 33960.0, "monoisotopic_mass": 33960.0 }, "refseq": { "ac": "XP_040519022", "name": "ubiquitin-conjugating enzyme E2Q-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022" }, "gene_names": [ { "name": "UBE2QL1", "type": "recommended", "evidence": [ { "id": "A0A1D5NUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ] }, { "name": "UBE2QL1", "type": "synonym", "evidence": [ { "id": "XP_040519022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2Q-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5NUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A1D5NUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8/entry#names_and_taxonomy" } ] }, { "name": "E2Q-like ubiquitin-conjugating enzyme 1", "type": "synonym", "evidence": [ { "id": "A0A1D5NUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2Q-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_040519022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040519022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022" } ] }, { "annotation": "Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8#function" }, { "database": "UniProtKB", "id": "ARBA00055455", "url": "https://www.uniprot.org/uniprotkb/ARBA00055455#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2QL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8", "locus": { "chromosome": "2", "start_pos": 79452681, "end_pos": 79469431, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000606", "url": "https://www.ensembl.org/id/ENSGALG00010000606" } ] } } ], "crossref": [ { "id": "A0A1D5NUJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032975", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420939", "url": "https://www.ncbi.nlm.nih.gov/gene/420939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RICRKVG", "url": "https://omabrowser.org/oma/group/RICRKVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUJ8", "url": "https://www.orthodb.org/?gene=A0A1D5NUJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040519022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLLRKIGLIRLHNRDTEDPKHHHHRSSQQGSSLRGRGGPKNGSNKPQPQGPPGGGCSSSSSSESSPGGRKTKKALEPAKQPPPPRSGGGREKPREAAREPGAGREAAPQRPGSSSGPGSAPLVPLASGSGPLAPAGRQQHCTQVRTRRLMKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEYILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG", "length": 312, "header": "tr|A0A1D5NUJ8-1|A0A1D5NUJ8_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2Q-like protein 1 OS=Gallus gallus OX=9031 GN=UBE2QL1 PE=4 SV=2 CANONICAL=A0A1D5NUJ8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8/entry", "sequence": { "sequence": "MATLLRKIGLIRLHNRDTEDPKHHHHRSSQQGSSLRGRGGPKNGSNKPQPQGPPGGGCSSSSSSESSPGGRKTKKALEPAKQPPPPRSGGGREKPREAAREPGAGREAAPQRPGSSSGPGSAPLVPLASGSGPLAPAGRQQHCTQVRTRRLMKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEYILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG", "length": 312, "header": "tr|A0A1D5NUJ8-1|A0A1D5NUJ8_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2Q-like protein 1 OS=Gallus gallus OX=9031 GN=UBE2QL1 PE=4 SV=2 CANONICAL=A0A1D5NUJ8-1" }, "locus": { "chromosome": "2", "start_pos": 79469232, "end_pos": 79453874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001287.1", "url": "https://www.ensembl.org/id/ENSGALT00010001287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000658.1", "url": "https://www.ensembl.org/id/ENSGALP00010000658.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUJ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NUJ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NUJ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUJ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUJ8" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 305, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 306 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUL1-1", "uniprot_ac": "A0A1D5NUL1", "uniprot_id": "A0A1D5NUL1_CHICK", "mass": { "chemical_mass": 145714.0, "monoisotopic_mass": 145714.0 }, "refseq": { "ac": "XP_418419", "name": "DENN domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419" }, "gene_names": [ { "name": "DENND3", "type": "recommended", "evidence": [ { "id": "A0A1D5NUL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ] }, { "name": "DENND3", "type": "synonym", "evidence": [ { "id": "XP_418419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419" } ] } ], "protein_names": [ { "name": "DENN domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A1D5NUL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_418419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418419.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1", "locus": { "chromosome": "2", "start_pos": 144947117, "end_pos": 144908732, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009237", "url": "https://www.ensembl.org/id/ENSGALG00010009237" } ] } } ], "crossref": [ { "id": "A0A1D5NUL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031380", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031380", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420309", "url": "https://www.ncbi.nlm.nih.gov/gene/420309", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420309", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420309", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSRDSIM", "url": "https://omabrowser.org/oma/group/CSRDSIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUL1", "url": "https://www.orthodb.org/?gene=A0A1D5NUL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y113", "url": "https://www.orthodb.org/?gene=A0A8V0Y113", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y119", "url": "https://www.orthodb.org/?gene=A0A8V0Y119", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2U0", "url": "https://www.orthodb.org/?gene=A0A8V0Y2U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25570", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25570", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418419", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y113", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y113", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y113-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y113-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y119", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y119", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y119-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y119-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLVFNMKPLQIIIPSREDPDSPVIDLDLHLPLLCFKPEQVLQIMTCILTERKMVFFSSDWALLTLVAECFMLYLHPLQWQHTFVPLLSRHMLDFVMAPTSFLMGCHADHFEEVSTEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPERNEVWASYSGSSDLYIWNTKDFASTPQKIHLQDCSEITCMIQVKNQMWVGSSGTSQGKIKGKIYVISAEKKTVEKELFGHADTVKALCSAEDRYVLSGAGKEEGKIAIWKVE", "length": 1270, "header": "tr|A0A1D5NUL1-1|A0A1D5NUL1_CHICK Isoform 1 of DENN domain-containing protein 3 OS=Gallus gallus OX=9031 GN=DENND3 PE=4 SV=2 CANONICAL=A0A1D5NUL1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1/entry", "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLVFNMKPLQIIIPSREDPDSPVIDLDLHLPLLCFKPEQVLQIMTCILTERKMVFFSSDWALLTLVAECFMLYLHPLQWQHTFVPLLSRHMLDFVMAPTSFLMGCHADHFEEVSTEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPERNEVWASYSGSSDLYIWNTKDFASTPQKIHLQDCSEITCMIQVKNQMWVGSSGTSQGKIKGKIYVISAEKKTVEKELFGHADTVKALCSAEDRYVLSGAGKEEGKIAIWKVE", "length": 1270, "header": "tr|A0A1D5NUL1-1|A0A1D5NUL1_CHICK Isoform 1 of DENN domain-containing protein 3 OS=Gallus gallus OX=9031 GN=DENND3 PE=4 SV=2 CANONICAL=A0A1D5NUL1-1" }, "locus": { "chromosome": "2", "start_pos": 144945827, "end_pos": 144908878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022031.1", "url": "https://www.ensembl.org/id/ENSGALT00010022031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012632.1", "url": "https://www.ensembl.org/id/ENSGALP00010012632.1" } ] } }, { "isoform_ac": "A0A8V0Y113-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y113/entry", "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLVFNMKPLQIIIPSREDPDSPVIDLDLHLPLLCFKPEQEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPERNEVWASYSGSSDLYIWNTKDFASTPQKIHLQDCSEITCMIQVKNQMWVGSSGTSQGKIKGKIYVISAEKKTVEKELFGHADTVKALCSAEDRYVLSGAGKEEGKIAIWKVE", "length": 1194, "header": "tr|A0A8V0Y113-1|A0A1D5NUL1_CHICK Computationally mapped isoform of DENN domain-containing protein 3 OS=Gallus gallus OX=9031 GN=DENND3 PE=4 SV=1 CANONICAL=A0A1D5NUL1-1" }, "locus": { "chromosome": "2", "start_pos": 144945827, "end_pos": 144908878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022040.1", "url": "https://www.ensembl.org/id/ENSGALT00010022040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012636.1", "url": "https://www.ensembl.org/id/ENSGALP00010012636.1" } ] } }, { "isoform_ac": "A0A8V0Y119-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y119/entry", "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLVFNMKPLQIIIPSREDPDSPVIDLDLHLPLLCFKPEQVLQIMTCILTERKMVFFSSDWALLTLVAECFMLYLHPLQWQHTFVPLLSRHMLDFVMAPTSFLMGCHADHFEEVSTEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPEVLQLNC", "length": 1164, "header": "tr|A0A8V0Y119-1|A0A1D5NUL1_CHICK Computationally mapped isoform of DENN domain-containing protein 3 OS=Gallus gallus OX=9031 GN=DENND3 PE=4 SV=1 CANONICAL=A0A1D5NUL1-1" }, "locus": { "chromosome": "2", "start_pos": 144943728, "end_pos": 144908878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022046.1", "url": "https://www.ensembl.org/id/ENSGALT00010022046.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012641.1", "url": "https://www.ensembl.org/id/ENSGALP00010012641.1" } ] } }, { "isoform_ac": "A0A8V0Y2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U0/entry", "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLIMTCILTERKMVFFSSDWALLTLVAECFMLYLHPLQWQHTFVPLLSRHMLDFVMAPTSFLMGCHADHFEEVSTEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPERNEVWASYSGSSDLYIWNTKDFASTPQKIHLQDCSEITCMIQVKNQMWVGSSGTSQGKIKGKIYVISAEKKTVEKELFGHADTVKALCSAEDRYVLSGAGKEEGKIAIWKVE", "length": 1230, "header": "tr|A0A8V0Y2U0-1|A0A1D5NUL1_CHICK Computationally mapped isoform of DENN domain-containing protein 3 OS=Gallus gallus OX=9031 GN=DENND3 PE=4 SV=1 CANONICAL=A0A1D5NUL1-1" }, "locus": { "chromosome": "2", "start_pos": 144945827, "end_pos": 144908878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022035.1", "url": "https://www.ensembl.org/id/ENSGALT00010022035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012634.1", "url": "https://www.ensembl.org/id/ENSGALP00010012634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420309", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420309", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AF91-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "DENND3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEAAPQHLELPWGLLELCALLGPPRDSLRGPEQGAQKKGAKSPPSLAPEVLSVFVPPFVSKEDSAAAAAGASSGTLGKAKRRSFRRKRDRPRAEPGRGPRGAEPEDASIPDGVDLLALPQLCFPGGVRVASEPEEDRVHFLVLTDVCGNRTHGVVAQYYRPLHDKHCFYNGKTQWEASGPSGGAAGCFVPFAVCVVSRFPYYNALKDCLSCLLTHLKLCKDFEVDNHIKDFAAKLSLIPSPPPGPLHLVFNMKPLQIVFPSRADPESPLVDLDLHLPLLCFRPEKVLQILTCLLTERRLVFFSSSWALLTLVAECFMAFLHPLQWQHTFVPILSRQMLDFVMAPTSFLMGCHLDHFAEVSKEADGLILINIDTGSITSSNSEDADVPDIPLLAAQTFIQSIQSLQLHHELHLAHLCASTDLNEGRASRRAWQHRLNCQIQQISLQLLVSIFREVKNHLNYEHRVFNSEEFLKTRAPGDQQFYKQVLETYMFHAFLKARLSRRMDAFAQMELHTQSEEDRINGTLLSPRRPTIEKMASRKSTLLQAAPRRKVVSMPDLQVIAVPELLPRNSSLRKIHTADGGGSHAAVSLALQPTYTFKIPEVHFPLLAQCVQVFYEDCVAQLSKAMVSLAPENSVLLARYFYLRGLVQLMQGRLLGALLDFQSLYKTDVHIFPADLVQRTVESLSGPERTQAERMPELRRLISEVMDKPVDAPKADDRVKNFELPKTHLQLDDFVKRVQESGVVKDTGVIHRLFEALTVGQQKQIDPETFREFYNCWKEAEAEAQEVSLPLSALEHLDKNECVYKLSSSVKTSLGVGKIAMTQKRLFLLTEGRPGYVEIATFRDMEEVRSTTVAFLLLRIPTLKIKTASKKEVFEANLKTECDLWHLMVKEMWAGKKLADEHKDPQYVQQALTHVLLMDAVVGTLQSPGAIYAASKLSHFDKLRSEMPMVVPKTTSETLKHKINPSAGETAPRAVDVLLYTPGHLDPAEKVEDAHPKLWCALNGGKVVVFDASSWTIHQHCFKVGNSKLNCMVMVEQSQVWVGSEDSVIYIINVHSMSCHKQLTDHRASVTGLVVQDGAPSAVYSCSADGTVLAWNVSSLRVTSRFQVPGDGLSSITLYRDRLWCCAGNSIVVMTANGFLRQELKIDEGFKDRSAFLAFQLLHEQEQLWAACSRYDSIYVWSLEDLARPPQRVCLRDCSAITCMIRVKQQIWVGGTGLSQGRPKGKIYVIDAERRTVEKELVAHADTVKTLCSAEDRYVLSGSGCEEGKIAIWKVE", "length": 1277 }, "evidence": [ { "id": "A0A1D5NUL1", "url": "https://omabrowser.org/oma/group/A0A1D5NUL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9P256-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "dennd3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADNVPCGLLEACVLLGVSNERLKELCPGKDADVLVEAEVLQVHAPPFITKDRSCNGGVDQGVAPAFSRVQKRRSFKKKKRERPVSTLSNSSQASESEELSVPQNIDLIALPQLCFPDGLRITNESREDSYHFLVFTDVFGNQTHGVVAQYCRPVQFQQDNVIYANGHRTNEHKRLYTTFSICVISKYPYYNALRDCLSCFLFQMKTSRVSDFDEQVKEFSAKLALVPIPPSGPLHVVFNLRPLQIELPSRLDVDRPVMDLDLHLPFLCFKPKQILQIISSILMEQRVVFLSTDWAKLTLVSECFMIFIHPLRWQHPFVPVLSRQMLDFIMAPTAYLMGCHTYHFQEVAEEIEDLVLIDIDQGTVSSSTSDRFDLPDVPLAARDCFIFRCGGLQLHYDLDVCGSSSQTDVNDLRAHRRLWQRKLNSSILNISMELIVNIFSEVCDFLNYEHRVFNSEEFLRSRDSTDSAFYRKVLDTHIFHSFLRERLNRKNDAFTRMQLNIRSETRRLKIMTESPRRPTMEEINRKHRAENGLNKRLGMSMPNLADSRSLTVPIRQMSMMSVRMPLQMGSWSPIKPVKTFKLPEFPPPLAYHYVQNYYHDLIGQLDRSISSASPDDSALLARYYYLRGLVNSVTGRHVDALADFQSLYKTDMEIFPAQLLNTLVEALPVEEKRIAERRTDLKRLMSRVRRENEKDRARLVDGGTVKRFELPKKHLQKEDFVRRVQESGIVKDLETIKRLFEALTLGVEDSCRSVFYLELDGQVKQVDPETFRFFYNFWKETEAAAQDVDLPAVVLEHLENDECVYKVSSSVKTSHGVGKIAMTQRRLFLLTEGRPGYVEITKFRDIEDVRISSAPFLLLRIPSLKIRTSLRRESFEANLKSECDLWHLMIKEMWAGRKMADQHKDPQFMEQALTNALLMDAVVGSLQSQKAIYAATKLAYFDKMKSEVPMMVPKTTSDTLKHKINPSLDQTSPQAVDVLLYTPGQLGVSDVDGGGNPKLWCALSDGKLLVFDAASWSMQHNSVQVGTSRLTCMLAVNEQQLWIGSKDSFIYIINPRSVSCNKQLTEHRCELTGLALEERADKFSQTVAYSCSEDCNVIVWDVSSLQVRRQFRVSCGRLQSMHVHNGMLWCCGRDCVLEVRRNGSVHRRISLPDHLLSSPKGFSSFLLFNESEQLWAGFADAGELCVWHCRDISKPFIRIQLKDCAAVTCMIRVKNQIWVGGYNGSVTDRRVRGKIYIVNTDRYTVEKELQAHADAVQTMCSAEDRYVLSGAAQDDGKIGIWKVE", "length": 1285 }, "evidence": [ { "id": "A0A1D5NUL1", "url": "https://omabrowser.org/oma/group/A0A1D5NUL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7FG86-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEPTARHLSLPSGLLELCALLGASQDSLRGLEQIGQKRGLKSVSSLAPEVLSVFVPPFTTQDDGQVSENSCMLSKTRRRSFRKKREKPRIEYWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGGVCVAPEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKTHWEPSVSSARRFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPCPPPGPLHLIFNMKPLQVVFPSRADPESPIIDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLIAECFVVYLHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLILIDIDHGSVTCSKSSDNDIDIPDVPLLLAQTFIQRVQSLQMHPDLHLAHLSSSTDLNEGLARRRAWQQTLNCKIQHISLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMTSRKSSPLHVTHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSSCKSSSSVFKVTPKSTYTFKIPEIHFPLMNQCVQAYYTDLITLLSKAMSLLGPGDSLLLARYFYLRGLIQVMQGQLLSALLDFQNLYKTDIGIFPADLVKSMVESMSASEWAQAERTPELRRLITEVLDKPGETPKADDAVKNFELPKKHMQLNDFVKRVQESGIVKDAVIIHRLFDALTVGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLTDHLDKNECVYKLSSSVKTNRGVGKIAMTQKRLFLLPEGRPGYVEIATFRNIEEVKNTTVAFLLLKIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKKLADDHKDPQYVQQALTNVLLMDAVVGTLQSPSAIYAASKLAYFDKMRSEMPMAVPKTTSETLKHKINPSAGETAPQAVDVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTIHQHCFKVGASKVNCMVMAEHSQVWVGSEDSVIYIINVHSMSCNKQLTDHRAAVTGLVVQNGKKPSEVYSCSLDGTVLAWNVSTLRVTSRFQLPYGDLMSISLHNDCLWCCTGHSLVVVTMQGFHRHELKINSPYKASTSLLAFQLLPEKEQLWVACAGCSDLYIWSLKDLGQPPRKTHLQDCTEVSCMIRVKRQIWVGGRGLSQGKPRGKIFVMDVEKMTVEKELVAHSDTVKTLCSAEDRYVLSGAGHEEGKIAIWKVE", "length": 1278 }, "evidence": [ { "id": "A0A1D5NUL1", "url": "https://omabrowser.org/oma/group/A0A1D5NUL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2RT67-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPAARHLSLPSGLLELCALLGASQDSLRGLEQIAQKRGVKSASSLVPEVLSVFVPPFTTKEDGQVPGASCALGKGRRRSFRKKREKPRMEPWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGCVCVASEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKSHWEPSVISARCFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPSPPPGPLHLIFNMKPLQVVFPSRADPESPIVDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLMAECFVAYLHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLVLIDIDHGSVTCSKSSDDNIDIPDVPLLLAQTFIQRVQSLQLHPDLHLAHLSASTDLNEGRARRRAWQQTLNCKIQHITLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMASRKASPLHITHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSNCRSSSPVLKVTPKSTYMFKIPDIHFPLESQCVQAYYTDFVTLLSKAMALLGPGDSLLLARYFYLRGLLHLMQGQLLSALLDFQNLYKTDIGIFPADLVKRTVESMSASERAQAERTPELRRLITEVFDKHGEAPKADDAVKNFELPKKHMQLNDFVKRVQESGIVKDAVIIHRLFDALTFGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLMEHLDKNECVYKLSSSVKTNRGVGKIAMTQKRLFLLTEGRPGYVEIATFRNIEEVKNSTVAFLLLRIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKQLADDHKDPQYVQQALTNVLLMDAVVGTLQSPSAIHAASKLAYFDNMKKKSPMAVPKTTSETLKHKINPSAGETAPQAIEVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTVHQHCFKVGSSKVNCMVMAEHNQVWVGSEDSVIYIINVHSMSCNKQLTDHRSPVTGLAVHNGKKPSEIYSCSLDGTVIAWNVSTLRVISRFQLSYGDLLSISLHNDRIWCCTVHKILVVTPQGFVRQELKHPKDASFLAFQLLPEEQQLWAASTGVSELYMWSLKDLDQPPQKTYLQDCSEVTCMIRVKRQIWVGGRGLSQGKTRGKIYVMDVEKVTVEKELVAHLDTVRTLCSAEDRYVLSGAGQEEGKIAIWKVE", "length": 1274 }, "evidence": [ { "id": "A0A1D5NUL1", "url": "https://omabrowser.org/oma/group/A0A1D5NUL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A2H4-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPGFVRSHWKPRAGHPAAARHSACHLFCFSAFGPPGPRRARPAAPDPAASRAPAPRPPQPSGPGLTRSEAGARWGPCPPKPAPRPAPPNALSPRLRGLEQIAQKRGVNGASSLVPEVLSVFVPPFTTKEDGQVVGASCTLSKGRRRSFRKKREKPRMESWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGGVCVASEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKSHWEPSMSSARRFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPSPPPGPLHLIFNMKPLQVVFPSRADPESPIIDLDLHLPLLCFRPEKVLQILTCILTEQRMVFFSSDWALLTLMAECFVAYVHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLVLIDIDLGSVTCSKSSDEDVDIPDVPLLLAQAFIQRVQSLQLHPDLHLAHLSASTDLNEGRARRRAWQQALNCKIQHITLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMASRKASPLNIAHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSSCKSSSPVLKVTPKSTYTFKIPEIHFPLVSQCVQAYFTDLVTLLSKAMALLGPGDSLLLARYFYLRGLIHLMQGQLLNALLDFQSLYKTDIRIFPADLVKGMVDSMSASERAQAERTPELRRLITEVFDKQGEAPKVDDAVKNFELPKKHMQLNDFVKRVQESGIVKDTTIIHRLFDALTVGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLVDHLDRNECVYKLSSSVKTNRGVGKIAMTQKRLFLLPEGRPSYVEIATFRNIEEVKSTTVAFLLLKIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKKLADDHKDPQYVQQALTNVLLMDAVVGTLQSSGAIYAASKLAYFDKMKNELPMAVPKTTSETLKHKINPSAGETAPQAIEVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTIHQHCFKVGSSKVNCMVMAEHSQVWVGSEDSVIYIINVHSMSCNKQLTDHRSAVTGLAVPSGKKPSAVYSCSLDGTVLAWNVSTLRVISRFQLQHGDLMSISLHNDRVFCCTARSILVVTLQGFVRQELRIQPSEEPSASFLAIQLLPEEQQLWVACTGVSELYIWSLKDLGQPPQKTHLQDCTEVTCMIRVKRQIWVGGRGLSQGKTRGKIYVMDVEKVTLEKELVAHSDTVRTLCSAEDRYVLSGAGGEEGKIAIWKVE", "length": 1345 }, "evidence": [ { "id": "A0A1D5NUL1", "url": "https://omabrowser.org/oma/group/A0A1D5NUL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1106, "end_pos": 1108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NUL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NUL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NUL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUL1" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 502, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1106, "end_pos": 1108 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 842, "end_pos": 844 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUP4-1", "uniprot_ac": "A0A1D5NUP4", "uniprot_id": "A0A1D5NUP4_CHICK", "mass": { "chemical_mass": 44996.0, "monoisotopic_mass": 44996.0 }, "refseq": { "ac": "XP_001233535", "name": "WD repeat-containing protein 86 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535" }, "gene_names": [ { "name": "WDR86", "type": "recommended", "evidence": [ { "id": "A0A1D5NUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4" } ] }, { "name": "WDR86", "type": "synonym", "evidence": [ { "id": "XP_001233535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535" } ] } ], "protein_names": [ { "name": "WD repeat domain 86", "type": "synonym", "evidence": [ { "id": "A0A1D5NUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 86 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233535.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR86", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4", "locus": { "chromosome": "2", "start_pos": 6231712, "end_pos": 6252587, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027123", "url": "https://www.ensembl.org/id/ENSGALG00010027123" } ] } } ], "crossref": [ { "id": "A0A1D5NUP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019690", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770203", "url": "https://www.ncbi.nlm.nih.gov/gene/770203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770203", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770203", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGGINWL", "url": "https://omabrowser.org/oma/group/HGGINWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUP4", "url": "https://www.orthodb.org/?gene=A0A1D5NUP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44489:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44489:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNGGSAVKVCADHQGGINWLSLSPDGQRLLTGSEDGTARLWSTADSQCHGHFQGHESYITFCHLENEAAFTCSADHTIRKWDVVTGQCLAIYRGHTSIVNRILVAKDYLFSGSYDRTARCWSVDKEKQIQEFRGHRNCVLTLAHYSSKDVLEEEEEEEEEEERVSRDLLVTGSTDCTVKVWWVSSGRCYQTLLGHTGAVLCLILDAPNRELFSGSTDYTIRTWNIVTGEQLKVFKEHQGSIICLELVNRHLYSGSADRTVKCWLVDTGERIQTYKAHKHSVSTLKYHAGILFTGSGDACARAFNSRSGVLQKIFRGHKFIINCIQIHNELLYTASHDGTLRIWDIRGICKRNKRRWKKERCAQGRSSQKGSLSRLFNNKVGCMVQQENGEHETVELM", "length": 398, "header": "tr|A0A1D5NUP4-1|A0A1D5NUP4_CHICK Isoform 1 of WD repeat domain 86 OS=Gallus gallus OX=9031 GN=WDR86 PE=4 SV=3 CANONICAL=A0A1D5NUP4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUP4/entry", "sequence": { "sequence": "MGNGGSAVKVCADHQGGINWLSLSPDGQRLLTGSEDGTARLWSTADSQCHGHFQGHESYITFCHLENEAAFTCSADHTIRKWDVVTGQCLAIYRGHTSIVNRILVAKDYLFSGSYDRTARCWSVDKEKQIQEFRGHRNCVLTLAHYSSKDVLEEEEEEEEEEERVSRDLLVTGSTDCTVKVWWVSSGRCYQTLLGHTGAVLCLILDAPNRELFSGSTDYTIRTWNIVTGEQLKVFKEHQGSIICLELVNRHLYSGSADRTVKCWLVDTGERIQTYKAHKHSVSTLKYHAGILFTGSGDACARAFNSRSGVLQKIFRGHKFIINCIQIHNELLYTASHDGTLRIWDIRGICKRNKRRWKKERCAQGRSSQKGSLSRLFNNKVGCMVQQENGEHETVELM", "length": 398, "header": "tr|A0A1D5NUP4-1|A0A1D5NUP4_CHICK Isoform 1 of WD repeat domain 86 OS=Gallus gallus OX=9031 GN=WDR86 PE=4 SV=3 CANONICAL=A0A1D5NUP4-1" }, "locus": { "chromosome": "2", "start_pos": 6251735, "end_pos": 6234385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065749.1", "url": "https://www.ensembl.org/id/ENSGALT00010065749.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040016.1", "url": "https://www.ensembl.org/id/ENSGALP00010040016.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770203", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7Z2-1", "protein_name": "WD repeat domain 86", "gene_name": "Wdr86", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSSGSALRVCAGHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCQLEDETAFTCSADCTIRSWDVRTGQCLQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQMSQEFRGHRNCVLTLAYSAPKDLPRDPCLEAAMGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLDVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVCTFSAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRFWDVRGLQSVPPLPRRPSAKRSLSRLFSNKVACAAPGPLQPA", "length": 380 }, "evidence": [ { "id": "A0A1D5NUP4", "url": "https://omabrowser.org/oma/group/A0A1D5NUP4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z757-1", "protein_name": "WD repeat domain 86", "gene_name": "Wdr86", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHLEDEAAFTCSADCTIRRWDVRTGQCLQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSAPEDLPQDPCMEAAMGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHAGTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVHGQVLYTASHDGALRLWDVRGLQSVPPLPRRPAAKRSLSRLFSNKVACAAPVPLQPA", "length": 380 }, "evidence": [ { "id": "A0A1D5NUP4", "url": "https://omabrowser.org/oma/group/A0A1D5NUP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86TI4-3", "protein_name": "WD repeat-containing protein 86", "gene_name": "WDR86", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQLEDEAAFTCSADCTIRRWDVLTGQCLQVYRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQVHGQVLYTASHDGALRLWDVRGLRGAPRPPPPMRSLSRLFSNKVGCAAAPLQPA", "length": 376 }, "evidence": [ { "id": "A0A1D5NUP4", "url": "https://omabrowser.org/oma/group/A0A1D5NUP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NUP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 398, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NUP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUP4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NUT3-1", "uniprot_ac": "A0A1D5NUT3", "uniprot_id": "A0A1D5NUT3_CHICK", "mass": { "chemical_mass": 34411.0, "monoisotopic_mass": 34411.0 }, "refseq": { "ac": "XP_001233122", "name": "fibrinogen silencer-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122" }, "gene_names": [ { "name": "FSBP", "type": "recommended", "evidence": [ { "id": "A0A1D5NUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3" } ] }, { "name": "FSBP", "type": "synonym", "evidence": [ { "id": "XP_001233122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122" } ] } ], "protein_names": [ { "name": "Fibrinogen silencer binding protein", "type": "synonym", "evidence": [ { "id": "A0A1D5NUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen silencer-binding protein", "type": "synonym", "evidence": [ { "id": "XP_001233122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FSBP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3", "locus": { "chromosome": "2", "start_pos": 125693874, "end_pos": 125700635, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012229", "url": "https://www.ensembl.org/id/ENSGALG00010012229" } ] } } ], "crossref": [ { "id": "A0A1D5NUT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NUT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037933", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037933", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770634", "url": "https://www.ncbi.nlm.nih.gov/gene/770634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770634", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERNNLPC", "url": "https://omabrowser.org/oma/group/ERNNLPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUT3", "url": "https://www.orthodb.org/?gene=A0A1D5NUT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8K2", "url": "https://www.orthodb.org/?gene=A0A8V0Y8K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233122", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNKCWDIIADNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETHSDCKSSISEPTKKVVEMIPQISNVCLRDRSGAQSASIDKETIAGTSSPQAVLDHHPATVMMKLQLEEDVKPPPSLIIDSQPSENVEQEEEHQLVHVMERSPSTSVSSVDMRVMMSPSPVPRRDEFFRLEVGERFRPMCGYDPQMLQMLKEEHQIMLENQRKIGLYVQEKRDGLKRKQQLEEELLRTKIKVEKLKAIRLRRDLPEYSII", "length": 298, "header": "tr|A0A1D5NUT3-1|A0A1D5NUT3_CHICK Isoform 1 of Fibrinogen silencer binding protein OS=Gallus gallus OX=9031 GN=FSBP PE=4 SV=2 CANONICAL=A0A1D5NUT3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUT3/entry", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNKCWDIIADNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETHSDCKSSISEPTKKVVEMIPQISNVCLRDRSGAQSASIDKETIAGTSSPQAVLDHHPATVMMKLQLEEDVKPPPSLIIDSQPSENVEQEEEHQLVHVMERSPSTSVSSVDMRVMMSPSPVPRRDEFFRLEVGERFRPMCGYDPQMLQMLKEEHQIMLENQRKIGLYVQEKRDGLKRKQQLEEELLRTKIKVEKLKAIRLRRDLPEYSII", "length": 298, "header": "tr|A0A1D5NUT3-1|A0A1D5NUT3_CHICK Isoform 1 of Fibrinogen silencer binding protein OS=Gallus gallus OX=9031 GN=FSBP PE=4 SV=2 CANONICAL=A0A1D5NUT3-1" }, "locus": { "chromosome": "2", "start_pos": 125700000, "end_pos": 125694823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029320.1", "url": "https://www.ensembl.org/id/ENSGALT00010029320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017024.1", "url": "https://www.ensembl.org/id/ENSGALP00010017024.1" } ] } }, { "isoform_ac": "A0A8V0Y8K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K2/entry", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNKCWDIIADNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETHSDCKSSISEPTKKVVEMIPQISNVCLRDRSGAQRLLESFYSAIVLPKNNKRKKSLNILALVSIKKQLLVPVHHRQCWITILLQS", "length": 174, "header": "tr|A0A8V0Y8K2-1|A0A1D5NUT3_CHICK Computationally mapped isoform of Fibrinogen silencer binding protein OS=Gallus gallus OX=9031 GN=FSBP PE=4 SV=1 CANONICAL=A0A1D5NUT3-1" }, "locus": { "chromosome": "2", "start_pos": 125700000, "end_pos": 125695269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029317.1", "url": "https://www.ensembl.org/id/ENSGALT00010029317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017023.1", "url": "https://www.ensembl.org/id/ENSGALP00010017023.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770634", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AE18-1", "protein_name": "DNA repair and recombination protein RAD54B", "gene_name": "RAD54B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRSAAPSQLQGNPLKKPRFIPPARSDPGLNEEKKLNSDVKLFEVPANKNAFLQSQNDPRICSFNLPPEESAREINREDNYREKYHLEASAKTTLDPHHTAHSAPKEVMVSNGQEEEPDSLVKYFSVVWCKASKKKHKKWEGDAVLIVKGKSFALKDLEGKDIGRGIGYKFKELEKIEEGQTMMIGGKEIEVMGVISPDDFSSGRCFQLGLSGALNSSQTPKKCTSNPFKSVCKLSSKENRQNGFQNCKPRHDPYAPNSLVMLRPDNNHQWMFNKNHFPIVDVVIDPHLVYHLRPHQREGIIFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDPDHKVEEFTKSPLYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALFSLPCEKRIILTGTPVQNDLQEFFSLIDFVNPGILGSLSCYRKIYEEPIITSRQPSASQEEKELGERRACELTCLTGLFILRRTQEVINKYLPPKIENVVFCRPGALQIELYRKLLNSQAVRFCLQGLMENSSHLICIGALKKLCNHPCLLFSSVKEKECSSAWDENEERRLYEDLLKVFPPDYNPLMFAEEESGKLQVLSKLLAVIHELRPAEKVVLVSNYTQTLNILQEVCRRHGYGCTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQDLSGAVVDLTKTSDHIQFSVEELKNLFTLHENSHCVTHDLLDCECTGENHPGDSLEKFPLSRTCQLGPHQQKSNSLKPLSMSQLKQWKHFSGDHLNLSDPFLERIRGNVSFFFQNITNQTTAT", "length": 906 }, "evidence": [ { "id": "A0A1D5NUT3", "url": "https://omabrowser.org/oma/group/A0A1D5NUT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7I3P3-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "Fsbp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLSLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSDFKSSISEPTKKVMEMIPQISSFCLIRDRNHIQSANLDEAAQAGTSSLQVMVDHHPVAITVEVKQEEDIKSSPPLFPNPQHNDTSEQREEHELVHVMEEPLSPSLSSVDMRMTSSPSSIPRRDDFFHHESGEHFRSLLRYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQQLEEELLRAKIEVEKLKATRLRHDLTEYSSL", "length": 299 }, "evidence": [ { "id": "A0A1D5NUT3", "url": "https://omabrowser.org/oma/group/A0A1D5NUT3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABI0P3K7-1", "protein_name": "Fibrinogen silencer binding protein", "gene_name": "FSBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"evidence": [ { "id": "A0A1D5NUT3", "url": "https://omabrowser.org/oma/group/A0A1D5NUT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BKE5-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "Fsbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLNLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSEFKSSVSEPTKQVMEMIPQIASFGLIRDRSHIQSANLDETAQAGTSSLQVMVDHHPVAITVEVKQEEDIKPSPPLVSNPQLSDTLEQREEHELMHVVEGSESPSLSSVDMRMTSSPSSVPRRDEIFHQESGEHFRSLLRCDPQVLQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQRLEEELLRAKIEVEKLKATRLRRDLPEYSSL", "length": 299 }, "evidence": [ { "id": "A0A1D5NUT3", "url": "https://omabrowser.org/oma/group/A0A1D5NUT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NV17-1", "uniprot_ac": "A0A1D5NV17", "uniprot_id": "A0A1D5NV17_CHICK", "mass": { "chemical_mass": 42014.0, "monoisotopic_mass": 42014.0 }, "refseq": { "ac": "XP_424279", "name": "actin, alpha skeletal muscle B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424279" }, "gene_names": [ { "name": "ACTBL2", "type": "recommended", "evidence": [ { "id": "A0A1D5NV17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV17" } ] }, { "name": "ACTBL2", "type": "synonym", "evidence": [ { "id": "XP_424279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424279" } ] } ], "protein_names": [ { "name": "Actin beta like 2", "type": "synonym", "evidence": [ { "id": "A0A1D5NV17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV17/entry#names_and_taxonomy" } ] }, { "name": "actin, alpha skeletal muscle B", "type": "synonym", "evidence": [ { "id": "XP_424279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424279" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424279" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV17", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACTBL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV17", "locus": {} } ], "crossref": [ { "id": "A0A1D5NV17", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NV17", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040415", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040415", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10224", "url": 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"MCDDDETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRIAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDVKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIGDRMQKEITALAPSTMKIKMIAPPERKYSVWIGGSILASLSTFQQMWISKDEYEESGPSIVHRKCF", "length": 377, "header": "tr|A0A1D5NV17-1|A0A1D5NV17_CHICK Isoform 1 of Actin beta like 2 OS=Gallus gallus OX=9031 GN=ACTBL2 PE=1 SV=1 CANONICAL=A0A1D5NV17-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NV17-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV17/entry", "sequence": { "sequence": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NV88-1", "uniprot_ac": "A0A1D5NV88", "uniprot_id": "A0A1D5NV88_CHICK", "mass": { "chemical_mass": 66970.0, "monoisotopic_mass": 66970.0 }, "refseq": { "ac": "XP_003643086", "name": "FERM domain-containing protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086" }, "gene_names": [ { "name": "FRMD3", "type": "recommended", "evidence": [ { "id": "A0A1D5NV88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ] }, { "name": "FRMD3", "type": "synonym", "evidence": [ { "id": "XP_003643086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086" } ] } ], "protein_names": [ { "name": "FERM domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A1D5NV88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88/entry#names_and_taxonomy" } ] }, { "name": "FERM domain-containing protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003643086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FRMD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88", "locus": { "chromosome": "Z", "start_pos": 40414972, "end_pos": 40574654, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015589", "url": "https://www.ensembl.org/id/ENSGALG00010015589" } ] } } ], "crossref": [ { "id": "A0A1D5NV88", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NV88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012577", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012577", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17102", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17102", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427452", "url": "https://www.ncbi.nlm.nih.gov/gene/427452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427452", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NV88", "url": "https://www.orthodb.org/?gene=A0A1D5NV88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSM1", "url": "https://www.orthodb.org/?gene=A0A8V0YSM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSW2", "url": "https://www.orthodb.org/?gene=A0A8V0YSW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZD9", "url": "https://www.orthodb.org/?gene=A0A8V0YZD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23280:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NV88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRFRSSSIRSLSPEMKCTVRLLDDSDISCHIQRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYMNDFKIFPKQSQKLEKKIAEIHKNEFRGQSPAVSEFKLLLKAHSLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLLKWCDVYKLKFEGKTFYVFGAQKEKKAVLTFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTMSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRTSITQSRSSPSLNKQLIINMEPLQPLLPSPCEEEEVPLDEDIQLPKEDEISVPVTSSSPVKNTGDNTDHAIEQEEKMKEEPLTISELVYNPSASLLPTPVDDEIDMLFDTCPRAENEKDDTDSFEELEADENAFMIAEEEELKEARRALRWSYDFVMGNIEVNAFVKSFSRLLLVGLGLMLLVFPLLLVLLESDLQISFLHEIRQTPEFQQFHIEYYCPLRQWVACKINFICDMLGSF", "length": 579, "header": "tr|A0A1D5NV88-1|A0A1D5NV88_CHICK Isoform 1 of FERM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=FRMD3 PE=4 SV=2 CANONICAL=A0A1D5NV88-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NV88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88/entry", "sequence": { "sequence": "MIRFRSSSIRSLSPEMKCTVRLLDDSDISCHIQRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYMNDFKIFPKQSQKLEKKIAEIHKNEFRGQSPAVSEFKLLLKAHSLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLLKWCDVYKLKFEGKTFYVFGAQKEKKAVLTFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTMSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRTSITQSRSSPSLNKQLIINMEPLQPLLPSPCEEEEVPLDEDIQLPKEDEISVPVTSSSPVKNTGDNTDHAIEQEEKMKEEPLTISELVYNPSASLLPTPVDDEIDMLFDTCPRAENEKDDTDSFEELEADENAFMIAEEEELKEARRALRWSYDFVMGNIEVNAFVKSFSRLLLVGLGLMLLVFPLLLVLLESDLQISFLHEIRQTPEFQQFHIEYYCPLRQWVACKINFICDMLGSF", "length": 579, "header": "tr|A0A1D5NV88-1|A0A1D5NV88_CHICK Isoform 1 of FERM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=FRMD3 PE=4 SV=2 CANONICAL=A0A1D5NV88-1" }, "locus": { "chromosome": "Z", "start_pos": 40558683, "end_pos": 40417821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037519.1", "url": "https://www.ensembl.org/id/ENSGALT00010037519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021715.1", "url": "https://www.ensembl.org/id/ENSGALP00010021715.1" } ] } }, { "isoform_ac": "A0A8V0YSM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSM1/entry", "sequence": { "sequence": "MAGLSLSGFKRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYMNDFKIFPKQSQKLEKKIAEIHKNEFRGQSPAVSEFKLLLKAHSLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLLKWCDVYKLKFEGKTFYVFGAQKEKKAVLTFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTMSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRTSITQSRSSPSLNKQLIINMEPLQPLLPSPCEEEEVPLDEDIQLPKEDEISVPVTSSSPVKNTGDNTDHAIEQEEKMKEEPLTISELVYNPSASLLPTPVDDEIDMLFDTCPRAENEKDDTDSFEELEADENAFMIAEEEELKEARRALRWSYDFVMGNIEVNAFVKSFSRLLLVGLGLMLLVFPLLLVLLESDLQISFLHEIRQTPEFQQFHIEYYCPLRQWVACKINFICDMLGSF", "length": 556, "header": "tr|A0A8V0YSM1-1|A0A1D5NV88_CHICK Computationally mapped isoform of FERM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=FRMD3 PE=4 SV=1 CANONICAL=A0A1D5NV88-1" }, "locus": { "chromosome": "Z", "start_pos": 40499189, "end_pos": 40417821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037518.1", "url": "https://www.ensembl.org/id/ENSGALT00010037518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021714.1", "url": "https://www.ensembl.org/id/ENSGALP00010021714.1" } ] } }, { "isoform_ac": "A0A8V0YSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSW2/entry", "sequence": { "sequence": "MIRFRSSSIRSLSPEMKCTVRLLDDSDISCHIQHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYMNDFKIFPKQSQKLEKKIAEIHKNEFRGQSPAVSEFKLLLKAHSLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLLKWCDVYKLKFEGKTFYVFGAQKEKKAVLTFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTMSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRTSITQSRSSPSLNKQLIINMEPLQPLLPSPCEEEEVPLDEDIQLPKEDEISVPVTSSSPVKNTGDNTDHAIEQEEKMKEEPLTISELVYNPSASLLPTPVDDEIDMLFDTCPRAENEKDDTDSFEELEADENAFMIAEEEELKEARRALRWSYDFVMGNIEVNAFVKSFSRLLLVGLGLMLLVFPLLLVLLESDLQISFLHEIRQTPEFQQFHIEYYCPLRQWVACKINFICDMLGSF", "length": 544, "header": "tr|A0A8V0YSW2-1|A0A1D5NV88_CHICK Computationally mapped isoform of FERM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=FRMD3 PE=4 SV=1 CANONICAL=A0A1D5NV88-1" }, "locus": { "chromosome": "Z", "start_pos": 40558683, "end_pos": 40417821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037521.1", "url": "https://www.ensembl.org/id/ENSGALT00010037521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021716.1", "url": "https://www.ensembl.org/id/ENSGALP00010021716.1" } ] } }, { "isoform_ac": "A0A8V0YZD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD9/entry", "sequence": { "sequence": "MLRETKGQFLIDHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKSHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYMNDFKIFPKQSQKLEKKIAEIHKNEFRGQSPAVSEFKLLLKAHSLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLLKWCDVYKLKFEGKTFYVFGAQKEKKAVLTFHTSTPAACKHLWKCGVENQAFYKYAKSSQIKTMSSSKIFFKGSRFRYSGKVAKEVVEASSKIQREPPEVHRTSITQSRSSPSLNKQLIINMEPLQPLLPSPCEEEEVPLDEDIQLPKEDEISVPVTSSSPVKNTGDNTDHAIEQEEKMKEEPLTISELVYNPSASLLPTPVDDEIDMLFDTCPRAENEKDDTDSFEELEADENAFMIAEEEELKEARRALRWSYDFVMGNIEVNAFVKSFSRLLLVGLGLMLLVFPLLLVLLESDLQISFLHEIRQTPEFQQFHIEYYCPLRQWVACKINFICDMLGSF", "length": 548, "header": "tr|A0A8V0YZD9-1|A0A1D5NV88_CHICK Computationally mapped isoform of FERM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=FRMD3 PE=4 SV=1 CANONICAL=A0A1D5NV88-1" }, "locus": { "chromosome": "Z", "start_pos": 40546685, "end_pos": 40417821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037524.1", "url": "https://www.ensembl.org/id/ENSGALT00010037524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021718.1", "url": "https://www.ensembl.org/id/ENSGALP00010021718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427452", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427452", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NV88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NV88-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 579, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NV88-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NV88" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NV88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV88" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 296, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVE2-1", "uniprot_ac": "A0A1D5NVE2", "uniprot_id": "A0A1D5NVE2_CHICK", "mass": { "chemical_mass": 44988.0, "monoisotopic_mass": 44988.0 }, "refseq": { "ac": "XP_024999232", "name": "ubiquitin-conjugating enzyme E2 Q1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232" }, "gene_names": [ { "name": "UBE2Q1", "type": "recommended", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "name": "UBE2Q1", "type": "synonym", "evidence": [ { "id": "XP_024999232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 Q1", "type": "synonym", "evidence": [ { "id": "XP_024999232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2Q1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2", "locus": { "chromosome": "25", "start_pos": 1950240, "end_pos": 1957643, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027902", "url": "https://www.ensembl.org/id/ENSGALG00010027902" } ] } } ], "crossref": [ { "id": "A0A1D5NVE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029450", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029450", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858564", "url": "https://www.ncbi.nlm.nih.gov/gene/100858564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858564", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFPKNHE", "url": "https://omabrowser.org/oma/group/VFPKNHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NVE2", "url": "https://www.orthodb.org/?gene=A0A1D5NVE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024999232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRAGAEEAAGSQAAAGGAGRSGAGLAAAPAGRLLKRELRLLESIFHRGHERFRIGSACPDEISCEFVPGAGARAGGSASRGPPPGPVRIHCNITESYPAVPPIWSVESDDPNLAAILERLVEVRKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQSTQEEVSSEEEDEEMPEDTEDLDHYEMKEEEPADGRKTEDEGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSPSFKGGYYAVELVNDSLYDWNVKLLKVDEDSALHNDLQILKEKEGTDFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKNQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 408, "header": "tr|A0A1D5NVE2-1|A0A1D5NVE2_CHICK Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2Q1 PE=4 SV=3 CANONICAL=A0A1D5NVE2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2/entry", "sequence": { "sequence": "MQRAGAEEAAGSQAAAGGAGRSGAGLAAAPAGRLLKRELRLLESIFHRGHERFRIGSACPDEISCEFVPGAGARAGGSASRGPPPGPVRIHCNITESYPAVPPIWSVESDDPNLAAILERLVEVRKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQSTQEEVSSEEEDEEMPEDTEDLDHYEMKEEEPADGRKTEDEGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSPSFKGGYYAVELVNDSLYDWNVKLLKVDEDSALHNDLQILKEKEGTDFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKNQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 408, "header": "tr|A0A1D5NVE2-1|A0A1D5NVE2_CHICK Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=UBE2Q1 PE=4 SV=3 CANONICAL=A0A1D5NVE2-1" }, "locus": { "chromosome": "25", "start_pos": 1957536, "end_pos": 1950641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067635.1", "url": "https://www.ensembl.org/id/ENSGALT00010067635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041378.1", "url": "https://www.ensembl.org/id/ENSGALP00010041378.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:100858564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858564", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N0E8-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2q1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A1D5NVE2", "url": "https://omabrowser.org/oma/group/A0A1D5NVE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2GV55-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2q1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A1D5NVE2", "url": "https://omabrowser.org/oma/group/A0A1D5NVE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSS2-1", "protein_name": "Ubiquitin-conjugating enzyme E2 Q1", "gene_name": "Ube2q1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A1D5NVE2", "url": "https://omabrowser.org/oma/group/A0A1D5NVE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z7E8-1", "protein_name": "Ubiquitin-conjugating enzyme E2 Q1", "gene_name": "UBE2Q1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A1D5NVE2", "url": "https://omabrowser.org/oma/group/A0A1D5NVE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVE2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V0YPW4-1", "Q5ZKX6-1", "R4GIV8-1", "A0A8V0ZBK2-1", "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0Z082-1", "A0A8V0YY10-1", "A0A8V0Z1W7-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V1ACU3-1", "A0A8V0Y059-1", "A0A8V0YFD9-1", "A0A1D5NVE2-1" ], "evidence": [ { "id": "R-GGA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983152" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XNP1", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZBK2", "gene_name": "UBA3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 401, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVP7-1", "uniprot_ac": "A0A1D5NVP7", "uniprot_id": "A0A1D5NVP7_CHICK", "mass": { "chemical_mass": 6578.0, "monoisotopic_mass": 6578.0 }, "refseq": { "ac": "NP_001289120", "name": "adropin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120" }, "gene_names": [ { "name": "ENHO", "type": "recommended", "evidence": [ { "id": "A0A1D5NVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7" } ] }, { "name": "ENHO", "type": "synonym", "evidence": [ { "id": "NP_001289120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120" } ] } ], "protein_names": [ { "name": "Energy homeostasis associated", "type": "synonym", "evidence": [ { "id": "A0A1D5NVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7/entry#names_and_taxonomy" } ] }, { "name": "adropin", "type": "synonym", "evidence": [ { "id": "NP_001289120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: BX932108.2 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX932108.2. On Oct 4, 2014 this sequence version replaced XP_001231843.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001289120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENHO", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7", "locus": { "chromosome": "Z", "start_pos": 8442992, "end_pos": 8444393, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012340", "url": "https://www.ensembl.org/id/ENSGALG00010012340" } ] } } ], "crossref": [ { "id": "A0A1D5NVP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030845", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030845", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768968", "url": "https://www.ncbi.nlm.nih.gov/gene/768968", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:768968", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768968", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKSSHEG", "url": "https://omabrowser.org/oma/group/QKSSHEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NVP7", "url": "https://www.orthodb.org/?gene=A0A1D5NVP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001289120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVP7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTALSTGAVVAISFNCIIALLILILFHILCKACRTPSCPKKSPASDADETRNEEKYLLQP", "length": 61, "header": "tr|A0A1D5NVP7-1|A0A1D5NVP7_CHICK Isoform 1 of Energy homeostasis associated OS=Gallus gallus OX=9031 GN=ENHO PE=4 SV=1 CANONICAL=A0A1D5NVP7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP7/entry", "sequence": { "sequence": "MGTALSTGAVVAISFNCIIALLILILFHILCKACRTPSCPKKSPASDADETRNEEKYLLQP", "length": 61, "header": "tr|A0A1D5NVP7-1|A0A1D5NVP7_CHICK Isoform 1 of Energy homeostasis associated OS=Gallus gallus OX=9031 GN=ENHO PE=4 SV=1 CANONICAL=A0A1D5NVP7-1" }, "locus": { "chromosome": "Z", "start_pos": 8444256, "end_pos": 8444074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029535.1", "url": "https://www.ensembl.org/id/ENSGALT00010029535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017167.1", "url": "https://www.ensembl.org/id/ENSGALP00010017167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768968", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768968", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUG5-1", "protein_name": "Energy homeostasis associated", "gene_name": "Enho", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSADVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP", "length": 76 }, "evidence": [ { "id": "A0A1D5NVP7", "url": "https://omabrowser.org/oma/group/A0A1D5NVP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HN26-1", "protein_name": "Adropin", "gene_name": "Enho", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSTDVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP", "length": 76 }, "evidence": [ { "id": "A0A1D5NVP7", "url": "https://omabrowser.org/oma/group/A0A1D5NVP7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6UWT2-1", "protein_name": "Adropin", "gene_name": "ENHO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSADVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP", "length": 76 }, "evidence": [ { "id": "A0A1D5NVP7", "url": "https://omabrowser.org/oma/group/A0A1D5NVP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1D8-1", "protein_name": "Adropin", "gene_name": "Enho", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSADVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP", "length": 76 }, "evidence": [ { "id": "A0A1D5NVP7", "url": "https://omabrowser.org/oma/group/A0A1D5NVP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NVP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 61, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NVP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVP7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVP9-1", "uniprot_ac": "A0A1D5NVP9", "uniprot_id": "A0A1D5NVP9_CHICK", "mass": { "chemical_mass": 104630.0, "monoisotopic_mass": 104630.0 }, "refseq": { "ac": "XP_414331", "name": "FYVE, RhoGEF and PH domain-containing protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414331" }, "gene_names": [ { "name": "FGD3", "type": "recommended", "evidence": [ { "id": "A0A1D5NVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ] }, { "name": "FGD3", "type": "synonym", "evidence": [ { "id": "XP_414331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414331" } ] } ], "protein_names": [ { "name": "FYVE, RhoGEF and PH domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A1D5NVP9", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_414331.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414331" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9", "locus": { "chromosome": "12", "start_pos": 6887755, "end_pos": 6992251, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027739", "url": "https://www.ensembl.org/id/ENSGALG00010027739" } ] } } ], "crossref": [ { "id": "A0A1D5NVP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005237", 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"categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414331", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD55", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P409", "url": "https://www.uniprot.org/uniprotkb/F1P409", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P409-1", "url": "https://www.uniprot.org/uniprotkb/F1P409-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLQWEGEETHPPRPAAAFVTAQPGAPPGPTRSSSGSAGARRREEMEPEGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 940, "header": "tr|A0A1D5NVP9-1|A0A1D5NVP9_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9/entry", "sequence": { "sequence": "MQLQWEGEETHPPRPAAAFVTAQPGAPPGPTRSSSGSAGARRREEMEPEGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 940, "header": "tr|A0A1D5NVP9-1|A0A1D5NVP9_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6989290, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067255.1", "url": "https://www.ensembl.org/id/ENSGALT00010067255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041159.1", "url": "https://www.ensembl.org/id/ENSGALP00010041159.1" } ] } }, { "isoform_ac": "A0A8V1A5H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5H1/entry", "sequence": { "sequence": "MLESLCKMRFWCSICLADGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 909, "header": "tr|A0A8V1A5H1-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6980071, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067250.1", "url": "https://www.ensembl.org/id/ENSGALT00010067250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041154.1", "url": "https://www.ensembl.org/id/ENSGALP00010041154.1" } ] } }, { "isoform_ac": "A0A8V1AAD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD2/entry", "sequence": { "sequence": "MHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 842, "header": "tr|A0A8V1AAD2-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6936268, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067247.1", "url": "https://www.ensembl.org/id/ENSGALT00010067247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041151.1", "url": "https://www.ensembl.org/id/ENSGALP00010041151.1" } ] } }, { "isoform_ac": "A0A8V1AAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAD7/entry", "sequence": { "sequence": "MCKTEALGLWTLVRPSACYGKPNPHPLDEHSGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 922, "header": "tr|A0A8V1AAD7-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6983376, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067252.1", "url": "https://www.ensembl.org/id/ENSGALT00010067252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041156.1", "url": "https://www.ensembl.org/id/ENSGALP00010041156.1" } ] } }, { "isoform_ac": "A0A8V1AD55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD55/entry", "sequence": { "sequence": "MLGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 893, "header": "tr|A0A8V1AD55-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6976834, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067249.1", "url": "https://www.ensembl.org/id/ENSGALT00010067249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041153.1", "url": "https://www.ensembl.org/id/ENSGALP00010041153.1" } ] } }, { "isoform_ac": "A0A8V1AFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR6/entry", "sequence": { "sequence": "MKNVGSSGKTLNLGDVVSYESKQKVGESAAVRGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 923, "header": "tr|A0A8V1AFR6-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6976441, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067248.1", "url": "https://www.ensembl.org/id/ENSGALT00010067248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041152.1", "url": "https://www.ensembl.org/id/ENSGALP00010041152.1" } ] } }, { "isoform_ac": "A0A8V1AFS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS1/entry", "sequence": { "sequence": "MQLQWEGEETHPPRPAAAFVTAQPGAPPGPTRSSSGSAGARRREEMEPEVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 883, "header": "tr|A0A8V1AFS1-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6989290, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067253.1", "url": "https://www.ensembl.org/id/ENSGALT00010067253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041157.1", "url": "https://www.ensembl.org/id/ENSGALP00010041157.1" } ] } }, { "isoform_ac": "A0A8V1AHM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM7/entry", "sequence": { "sequence": "MTLSSPQLHFFPFSTILPVCVQGGHWELHPASVLCGWVCGTRVQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 878, "header": "tr|A0A8V1AHM7-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=1 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6934047, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067246.1", "url": "https://www.ensembl.org/id/ENSGALT00010067246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041150.1", "url": "https://www.ensembl.org/id/ENSGALP00010041150.1" } ] } }, { "isoform_ac": "F1P409-1", "url": "https://www.uniprot.org/uniprotkb/F1P409/entry", "sequence": { "sequence": "MDLQPAGCPCSPFQIKCHIDSNPALEACGELQHISPAQCIHQTGRKPKTKTPLAKMHPLQKPQVPPKPVHLKPGQERIPPAPSRPLPADPKSSRSLAPGEDEIPISAGVNTLIEKFESIRQPVHILQRNQLNLALKMEPGLDSSKQSSSCDCDMVASSSCSTNEKSEPDENEPDVPCSADLSNTDIMKIKELSIGDNKSHEDCTAVNESKEPSRELGNKDSTAELNGNGKIPNRDSGIDSPSCSVAGETFPSEEGAEQKKPGVSGNPGEMEPDRKSTRSSSAEQKRDSTQDEDSDIDEGSSEEQETAEVPKLEYMDVNKCTEPQKLFNIANELLHTEEAYVKRLHLLDQVFCTKLSEAGISSEVITGIFSNISSIYCFHGQFLLPELKTRITQEWNVNPRLGDILQKLAPFLKMYGEYVKNFDRAMDMVNTCMQRSSPFKDVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEESPDRKDAEKSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTAQDRYLFLFNSMVLYCVPKLRLIGQKFSVREKMDIGGLQVQEIAKQNVAHTFSITGKKRSLELQARTEEEKREWIQVIQATIEKHKQNSETFRAFNSSFSQEEEHLPDSSIASTSSVESMPGADSGAFGGSDSCRKSSKSKRDKEKQTCKSCSESFNSITKRRHHCKQCGAVICAKCSEFKPLADNSRHNRVCKECFLQLPISPCSPGVEAVGEQKKRQAAEKQSLLAPENSLFSSYLQFLEKGKTWYKMWVTIPKTEPLVLYLQGMSQDGRGPRPIPLPGYEVSFPGSGEKFEVKHVFKLCQSQQTIYFSAEDEELQLKWMEILAKAAKGETEDVAEGLSSP", "length": 897, "header": "tr|F1P409-1|A0A1D5NVP9_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Gallus gallus OX=9031 GN=FGD3 PE=4 SV=3 CANONICAL=A0A1D5NVP9-1" }, "locus": { "chromosome": "12", "start_pos": 6992171, "end_pos": 6889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067256.1", "url": "https://www.ensembl.org/id/ENSGALT00010067256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041160.1", "url": "https://www.ensembl.org/id/ENSGALP00010041160.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NVP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 940, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NVP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVP9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 31 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVS3-1", "uniprot_ac": "A0A1D5NVS3", "uniprot_id": "A0A1D5NVS3_CHICK", "mass": { "chemical_mass": 23675.0, "monoisotopic_mass": 23675.0 }, "refseq": { "ac": "XP_001231676", "name": "dermatopontin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676" }, "gene_names": [ { "name": "DPT", "type": "recommended", "evidence": [ { "id": "A0A1D5NVS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3" } ] }, { "name": "DPT", "type": "synonym", "evidence": [ { "id": "XP_001231676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676" } ] } ], "protein_names": [ { "name": "Dermatopontin", "type": "synonym", "evidence": [ { "id": "A0A1D5NVS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3/entry#names_and_taxonomy" } ] }, { "name": "dermatopontin", "type": "synonym", "evidence": [ { "id": "XP_001231676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001231676.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPT", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3", "locus": { "chromosome": "1", "start_pos": 84192670, "end_pos": 84165385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005369", "url": "https://www.ensembl.org/id/ENSGALG00010005369" } ] } } ], "crossref": [ { "id": "A0A1D5NVS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039376", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039376", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768904", "url": "https://www.ncbi.nlm.nih.gov/gene/768904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768904", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RAGMEWS", "url": "https://omabrowser.org/oma/group/RAGMEWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NVS3", "url": "https://www.orthodb.org/?gene=A0A1D5NVS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15040", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15040", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15040:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15040:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLVLLWVFLPLVSVAWGQYGDYYYGPYNYGDNDEWANVYRQGFNFQCPHGQVIVAIRSVFSKKEGSDRLWNYACMPAAQSLGEPTECWWEEINRAGTEWYQTCSNNGLVAGFQSQYFPSVLDREWQFYCCRYSRRCPYSCWLTTEYPGHYGEDMDMMMYTYDYYIRGATTTFSAVDRDRQWKFIVCRMTEYDCPFQNV", "length": 199, "header": "tr|A0A1D5NVS3-1|A0A1D5NVS3_CHICK Isoform 1 of Dermatopontin OS=Gallus gallus OX=9031 GN=DPT PE=1 SV=1 CANONICAL=A0A1D5NVS3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3/entry", "sequence": { "sequence": "MDLVLLWVFLPLVSVAWGQYGDYYYGPYNYGDNDEWANVYRQGFNFQCPHGQVIVAIRSVFSKKEGSDRLWNYACMPAAQSLGEPTECWWEEINRAGTEWYQTCSNNGLVAGFQSQYFPSVLDREWQFYCCRYSRRCPYSCWLTTEYPGHYGEDMDMMMYTYDYYIRGATTTFSAVDRDRQWKFIVCRMTEYDCPFQNV", "length": 199, "header": "tr|A0A1D5NVS3-1|A0A1D5NVS3_CHICK Isoform 1 of Dermatopontin OS=Gallus gallus OX=9031 GN=DPT PE=1 SV=1 CANONICAL=A0A1D5NVS3-1" }, "locus": { "chromosome": "1", "start_pos": 84191339, "end_pos": 84165522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012759.1", "url": "https://www.ensembl.org/id/ENSGALT00010012759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007323.1", "url": "https://www.ensembl.org/id/ENSGALP00010007323.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768904", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZVB7-1", "protein_name": "Dermatopontin", "gene_name": "DPT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLTLLWVLLPLVTVAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPSECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "length": 201 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B2RZ77-1", "protein_name": "Dermatopontin", "gene_name": "Dpt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLTLLWVLLPLVSTAWGQYGDYGYHPYQQYQDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPGHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV", "length": 202 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HE53-1", "protein_name": "Dermatopontin", "gene_name": "Dpt", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLTLLWVLLPLVTTAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "length": 201 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P19427-1", "protein_name": "Dermatopontin", "gene_name": "DPT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLTLLWVLLPLVTVAWGQYGDYGYSYHQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "length": 201 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q07507-1", "protein_name": "Dermatopontin", "gene_name": "DPT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLSLLWVLLPLVTMAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV", "length": 201 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZZ6-1", "protein_name": "Dermatopontin", "gene_name": "Dpt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV", "length": 201 }, "evidence": [ { "id": "A0A1D5NVS3", "url": "https://omabrowser.org/oma/group/A0A1D5NVS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NVS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 199, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NVS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVS3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NVS8-1", "uniprot_ac": "A0A1D5NVS8", "uniprot_id": "MSL2_CHICK", "mass": { "chemical_mass": 62252.0, "monoisotopic_mass": 62252.0 }, "refseq": { "ac": "XP_426675", "name": "E3 ubiquitin-protein ligase MSL2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675" }, "gene_names": [ { "name": "MSL2", "type": "recommended", "evidence": [ { "id": "A0A1D5NVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ] }, { "name": "MSL2", "type": "synonym", "evidence": [ { "id": "XP_426675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase MSL2", "type": "recommended", "evidence": [ { "id": "A0A1D5NVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A1D5NVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase MSL2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675" } ] }, { "name": "MSL-2", "type": "synonym", "evidence": [ { "id": "A0A1D5NVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal-2 homolog", "type": "synonym", "evidence": [ { "id": "A0A1D5NVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426675.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675" } ] }, { "annotation": "Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction (By similarity). The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac (By similarity). MSL2 plays a key role in gene dosage by ensuring biallelic expression of a subset of dosage-sensitive genes, including many haploinsufficient genes (By similarity). Acts by promoting promoter-enhancer contacts, thereby preventing DNA methylation of one allele and creating a methylation-free environment for methylation-sensitive transcription factors such as SP1, KANSL1 and KANSL3 (By similarity). Also acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A (By similarity). Also involved in the DNA damage response by mediating ubiquitination of TP53/p53 and TP53BP1 (PubMed:23874665).", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8#function" }, { "database": "UniProtKB", "id": "Q69ZF8", "url": "https://www.uniprot.org/uniprotkb/Q69ZF8#function" }, { "database": "UniProtKB", "id": "Q9HCI7", "url": "https://www.uniprot.org/uniprotkb/Q9HCI7#function" }, { "database": "PubMed", "id": "23874665", "url": "https://glygen.org/publication/PubMed/23874665" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8", "locus": { "chromosome": "9", "start_pos": 263236, "end_pos": 278271, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022719", "url": "https://www.ensembl.org/id/ENSGALG00010022719" } ] } } ], "crossref": [ { "id": "A0A1D5NVS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039294", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039294", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13122", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13122", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429119", "url": "https://www.ncbi.nlm.nih.gov/gene/429119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TEVCDSN", "url": "https://omabrowser.org/oma/group/TEVCDSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NVS8", "url": "https://www.orthodb.org/?gene=A0A1D5NVS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL0", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16048:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16048:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16682", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16682", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0A1D5NVS8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0A1D5NVS8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-3214847", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214847", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_426675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPVNATALYVSASRLVLNYDPGDPQSFTEINKLLPYFRQSLSCCVCGNLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTPLARDIIQAVDCSADLLALLKDGSPLHEETEKSSDTALALCLTHSPVPSTSELTSDPPATLTSKPESTQNVDIRGSVINGLPNCNGLSVDKLGVNIPSPEHANTIDVCSTGEYMKNEDNSSSLQPVCDPVSTSDLCTTGIDICSFSEDIKPGGSLLLSVEEVLRSLETVSNTEVCGSNLQPSLEANVTNGPFLQLSPPPLSHNIFVSTDASPHGISCTAATPKVVKLNRKRSRSESDSEKVQPLPISSIICGPTLGASAPVTVKQENKMSLQPVATVPNGGTTPKISKTVLLSNKSVKKNLEHAPKKSHPKAKPGVLKTKDKAKEKVPSSNVMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDVRYDC", "length": 579, "header": "sp|A0A1D5NVS8-1|MSL2_CHICK Isoform 1 of E3 ubiquitin-protein ligase MSL2 OS=Gallus gallus OX=9031 GN=MSL2 PE=3 SV=1 CANONICAL=A0A1D5NVS8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8/entry#A0A1D5NVS8-1", "sequence": { "sequence": "MNPVNATALYVSASRLVLNYDPGDPQSFTEINKLLPYFRQSLSCCVCGNLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTPLARDIIQAVDCSADLLALLKDGSPLHEETEKSSDTALALCLTHSPVPSTSELTSDPPATLTSKPESTQNVDIRGSVINGLPNCNGLSVDKLGVNIPSPEHANTIDVCSTGEYMKNEDNSSSLQPVCDPVSTSDLCTTGIDICSFSEDIKPGGSLLLSVEEVLRSLETVSNTEVCGSNLQPSLEANVTNGPFLQLSPPPLSHNIFVSTDASPHGISCTAATPKVVKLNRKRSRSESDSEKVQPLPISSIICGPTLGASAPVTVKQENKMSLQPVATVPNGGTTPKISKTVLLSNKSVKKNLEHAPKKSHPKAKPGVLKTKDKAKEKVPSSNVMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDVRYDC", "length": 579, "header": "sp|A0A1D5NVS8-1|MSL2_CHICK Isoform 1 of E3 ubiquitin-protein ligase MSL2 OS=Gallus gallus OX=9031 GN=MSL2 PE=3 SV=1 CANONICAL=A0A1D5NVS8-1" }, "locus": { "chromosome": "9", "start_pos": 278182, "end_pos": 265817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055240.1", "url": "https://www.ensembl.org/id/ENSGALT00010055240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033423.1", "url": "https://www.ensembl.org/id/ENSGALP00010033423.1" } ] } }, { "isoform_ac": "A0A8V0ZPL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL0/entry", "sequence": { "sequence": "MTIGNLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTPLARDIIQAVDCSADLLALLKDGSPLHEETEKSSDTALALCLTHSPVPSTSELTSDPPATLTSKPESTQNVDIRGSVINGLPNCNGLSVDKLGVNIPSPEHANTIDVCSTGEYMKNEDNSSSLQPVCDPVSTSDLCTTGIDICSFSEDIKPGGSLLLSVEEVLRSLETVSNTEVCGSNLQPSLEANVTNGPFLQLSPPPLSHNIFVSTDASPHGISCTAATPKVVKLNRKRSRSESDSEKVQPLPISSIICGPTLGASAPVTVKQENKMSLQPVATVPNGGTTPKISKTVLLSNKSVKKNLEHAPKKSHPKAKPGVLKTKDKAKEKVPSSNVMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDVRYDC", "length": 535, "header": "tr|A0A8V0ZPL0-1|A0A8V0ZPL0_CHICK Computationally mapped isoform of MSL complex subunit 2 OS=Gallus gallus OX=9031 GN=MSL2 PE=3 SV=1 CANONICAL=A0A1D5NVS8-1" }, "locus": { "chromosome": "9", "start_pos": 268663, "end_pos": 265817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055236.1", "url": "https://www.ensembl.org/id/ENSGALT00010055236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033420.1", "url": "https://www.ensembl.org/id/ENSGALP00010033420.1" } ] } }, { "isoform_ac": "A0A8V0ZPL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL6/entry", "sequence": { "sequence": "MFQGKKKKKKQCRLRARNCKLPVTALGLLLCTAGNLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTPLARDIIQAVDCSADLLALLKDGSPLHEETEKSSDTALALCLTHSPVPSTSELTSDPPATLTSKPESTQNVDIRGSVINGLPNCNGLSVDKLGVNIPSPEHANTIDVCSTGEYMKNEDNSSSLQPVCDPVSTSDLCTTGIDICSFSEDIKPGGSLLLSVEEVLRSLETVSNTEVCGSNLQPSLEANVTNGPFLQLSPPPLSHNIFVSTDASPHGISCTAATPKVVKLNRKRSRSESDSEKVQPLPISSIICGPTLGASAPVTVKQENKMSLQPVATVPNGGTTPKISKTVLLSNKSVKKNLEHAPKKSHPKAKPGVLKTKDKAKEKVPSSNVMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDVRYDC", "length": 565, "header": "tr|A0A8V0ZPL6-1|A0A8V0ZPL6_CHICK Computationally mapped isoform of MSL complex subunit 2 OS=Gallus gallus OX=9031 GN=MSL2 PE=3 SV=1 CANONICAL=A0A1D5NVS8-1" }, "locus": { "chromosome": "9", "start_pos": 277694, "end_pos": 265817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055243.1", "url": "https://www.ensembl.org/id/ENSGALT00010055243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033425.1", "url": "https://www.ensembl.org/id/ENSGALP00010033425.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Msl2 is a novel component of the vertebrate DNA damage response.", "journal": "PloS one", "date": "2013", "authors": "Lai Z, Moravcova S, Canitrot Y, Andrzejewski LP, Walshe DM, Rea S", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "reference": [ { "type": "PubMed", "id": "23874665", "url": "https://glygen.org/publication/PubMed/23874665" } ] } ], "pathway": [ { "id": "R-GGA-3214847", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214847", "resource": "Reactome", "description": "HATs acetylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AT15-1", "protein_name": "MSL complex subunit 2", "gene_name": "Msl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTLSPVISVYPSLQSSELNQFQFKRLISELHYMKLYFSFAKICAFLLPPLGHLLQDPIAPTNSTCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTADPQAALSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHPNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCSNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKLSLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKSKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 581 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MRF9-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "MSL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTALARDIIEAVDCSSDILALLNDGSLFGEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPISESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVASDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKTVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 577 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QVJ4-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "msl2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPVNATTLYVSACRSVLQCDPRDPQALAEIYKLLPFFRQSLACLVCGNLLQDPIAPTNSSCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLCILVDCYKKLCEYIADSPLAQHISSTVEGSSDILSLLNEGLEGLGEESLSLSLTNQSPTPSTSETLPDEGQSPSTEIKEQGLSPLGVNGLQDCNGLTNVEELTASLPSLEASVPDSVESSGGDEVKQESFTNEIPVCEAVAAAGEELCTSTMDICGFSEDIKHDGGTLLLSVEEVLRTLEPDHVSQDECPAILQSTLESSGNLNGPFSSVDSSRQLSSLPQDSHEILVPQHPVSQQNQQHLGISCSAVTPRIPRSNRKRSRSESDSEKIQPLPISTFICGPTLGASAPVQIKCEPKSPAQTIPHMAVVPNGGGLPKVGKTLLVPAKPVKKTLDHHGPKKAYTKSKQGTPKSKEKMKDRILTSALIPGSPTKVVYKKAQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNATGSGAGGMLNVSTAAGSPVASFLATGPHEDKGFDEPLDMRFD", "length": 598 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SL85-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "MSL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPISESTLSIAIGSSVINGLPPYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKTVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 577 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I1E2-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "Msl2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTADPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGLNLPSPEHPNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPTLHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKSKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 577 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P50534-1", "protein_name": "E3 ubiquitin-protein ligase msl-2", "gene_name": "msl-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQTAYLKVTRIAMRSASNLSKRRVEELNSGLGELRQLLSCVVCCQLLVDPYSPKGKRCQHNVCRLCLRGKKHLFPSCTQCEGCSDFKTYEENRMMAAQLLCYKTLCVHLLHSALFGELAGMRPQVARELVPRIKLPPKTTQEFIREGSNISDTFDIFLPQPDLPFLKDMPTSLPAETPPTSAVTTPELPYDHHLNISDIEAEAAATAEQGHFSPLPLLPTGSRMGMLSHAGQIVIATESSESGFMDQAWTDQVDLSGTVSVSKYTNSGNNFAVSYVMPTSATTKFDPQELQIGQVVQMADSTQLAVLAAVEETVETSTQLTVLSTTVEETVETSTQLEVLTSAEEPNEISDQLANLQVEESDEALVEETVEEAEGTSIPSEVVAEHMEEDQHLDVHTSQSPTQTEMEEAVEEHVATKTQLGHVQTELQDAESLQKDFEDAKAAAEEAKEKEKDLHAISAELQKEDSDEPTLKRKRTRTLKASQAAKIEPVPSEVKTKVQSGKGALRRIRGKDKEEKVKPPKPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVESDEDDDLEDFEMPKDVPEPMTQSEEPVVAEPRQEENSMAPPDSSAPISLVPLNNLQQSQHPLVLVQNEKGEYQGFNIFQGSKPLDPVTVGFTIRVQLQHTDGFGSLPQYAYIMPTIDPPNPPAPSLSPPPPPAPDREVIEPPAKKFRTSRTRRGRANFSALDTVDELVSGGSRSNSAAGDRSSATDNAHSLFEEIMSGSDDL", "length": 773 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q69ZF8-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "Msl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTADPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHPNTIDVCNTVDIKTEDLSDNLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKSKPGILKKDKAVKEKMPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 577 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCI7-1", "protein_name": "E3 ubiquitin-protein ligase MSL2", "gene_name": "MSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "length": 577 }, "evidence": [ { "id": "A0A1D5NVS8", "url": "https://omabrowser.org/oma/group/A0A1D5NVS8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "promoter-enhancer loop anchoring activity", "id": "GO:0140585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140585", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "histone H2B ubiquitin ligase activity", "id": "GO:0141054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141054", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-3321883", "name": "MSL acetylates histone H4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-GGA-427469" ], "enzyme_list": [ "A0A8V0X885-1", "A0A1D5NVS8-1" ], "evidence": [ { "id": "R-GGA-3321883", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3321883" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-427469", "participant_name": "H4-VI [nucleoplasm]", "crossref": [ { "id": "1EQZ", "database": "PDB", "url": "" }, { "id": "NP_001268414.1", "database": "RefSeq", "url": "" }, { "id": "3C9K", "database": "PDB", "url": "" }, { "id": "2HIO", "database": "PDB", "url": "" }, { "id": "1HQ3", "database": "PDB", "url": "" }, { "id": "P62801", "database": "UniProt", "url": "" }, { "id": "P62801", "database": "PRO", "url": "" }, { "id": "1HIO", "database": "PDB", "url": "" }, { "id": "NP_001032932.1", "database": "RefSeq", "url": "" }, { "id": "1TZY", "database": "PDB", "url": "" 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16208:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16208:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15290", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15290", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLRESGKEEQKAHPEKEVSRSRIPRLVLRPQPPQQHKVSPASESPFSEEESREFNPPSSSGGSARTISSNSFCSDDTGCPSSQSVSPVKTPSDAGHSPISFCTGSDGDFSRKKFNAGTMSEGNSQLARYKKETKTILVKPGSEADFSSSSSTGSISAPEVHMSAPGSKRSSFSRNRGPYGRNSGSSSYKSGASPPASREKDHLSTLCRSQQNPVNIHQNYGVSSPSSSNSGSYKGSDTSPIMRRSGRYLTCVDHHSAKPQNPEQYLTPLQQKEVTVRHLKTKLKESQSKLKERETEIEELKTQLGRMREDWIEEECHRVEAQLALKEAKKEIKQLKQVIETMKNNLAEKDKGIQKYFIDINIQNKKLESLLHSMEMAQNGSLRDEDVSDAPGKPLALYAKLPDTLITEEQALEVDSGVLLNEDIANGNDSFQETFTTAGVELADPAFFISAVDQEVLENVPDEKLRSSRKEERSDIVMVEQSVQTDVVPYSLNVERLIQNIFGSQDVSPLSPPSSLKELSDFSSGSFSDSAIVVDLTPSDPNSAILLSPMESPCRKVDYGVDENRVMKELDFTEMRDEVFGYVNNSSETGVMQRHWSGSLLVDLLAVAAPVVPTVMWVFSTQRGGVDPIYNIGALLRGCCLVALHSLRRTPFNIRT", "length": 658, "header": "tr|A0A1D5NVV7-1|A0A1D5NVV7_CHICK Isoform 1 of Syntabulin OS=Gallus gallus OX=9031 GN=SYBU PE=4 SV=2 CANONICAL=A0A1D5NVV7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7/entry", "sequence": { "sequence": "MGPLRESGKEEQKAHPEKEVSRSRIPRLVLRPQPPQQHKVSPASESPFSEEESREFNPPSSSGGSARTISSNSFCSDDTGCPSSQSVSPVKTPSDAGHSPISFCTGSDGDFSRKKFNAGTMSEGNSQLARYKKETKTILVKPGSEADFSSSSSTGSISAPEVHMSAPGSKRSSFSRNRGPYGRNSGSSSYKSGASPPASREKDHLSTLCRSQQNPVNIHQNYGVSSPSSSNSGSYKGSDTSPIMRRSGRYLTCVDHHSAKPQNPEQYLTPLQQKEVTVRHLKTKLKESQSKLKERETEIEELKTQLGRMREDWIEEECHRVEAQLALKEAKKEIKQLKQVIETMKNNLAEKDKGIQKYFIDINIQNKKLESLLHSMEMAQNGSLRDEDVSDAPGKPLALYAKLPDTLITEEQALEVDSGVLLNEDIANGNDSFQETFTTAGVELADPAFFISAVDQEVLENVPDEKLRSSRKEERSDIVMVEQSVQTDVVPYSLNVERLIQNIFGSQDVSPLSPPSSLKELSDFSSGSFSDSAIVVDLTPSDPNSAILLSPMESPCRKVDYGVDENRVMKELDFTEMRDEVFGYVNNSSETGVMQRHWSGSLLVDLLAVAAPVVPTVMWVFSTQRGGVDPIYNIGALLRGCCLVALHSLRRTPFNIRT", "length": 658, "header": "tr|A0A1D5NVV7-1|A0A1D5NVV7_CHICK Isoform 1 of Syntabulin OS=Gallus gallus OX=9031 GN=SYBU PE=4 SV=2 CANONICAL=A0A1D5NVV7-1" }, "locus": { "chromosome": "2", "start_pos": 131626512, "end_pos": 131583496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020170.1", "url": "https://www.ensembl.org/id/ENSGALT00010020170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011718.1", "url": "https://www.ensembl.org/id/ENSGALP00010011718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420277", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A508-1", "protein_name": "Syntabulin", "gene_name": "Sybu", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPYLPVQSLRPPAPVPTCSEAPGAAALAPEAKRPRGPERAGGCRTTCANPAGAGGAGRGWLLQPQRKPVATRRVAGRRPSPTQASRAFRHTVWTAQWTRSAKETVPPPGRRRRRGEPAGNDEMGPLRESKKEQRVQHQEKEFSRSRIPRLILRPHLPQQQQQQQNKVSPASESPFSEEESREFNPSSSGRSARTISSNSFCSDDTGCPSSQSVSPVKTPSDTGHSPIGFCPGSDEDFTRKKCRIGMVGEGNIQSARYKKESKGGIIKPGSEADFSSSSSTGSISAPEVHMSTTGNKRASFSRNRGPHGRSNGAPSHKSGSSPPSPREKDLVSMLCRNPLSPSNIHPSYAPSSPSSSNSGSYKGSDCSPVMRRSGRYMSCGENHGVKPPNPEQYLTPLQQKEVTVRHLRTKLKESERRLHERESEIMELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHNSSLRDELCLDFSFDSPEKSLPLSSTYDKMADGLSLEEQITEEGADSELLVGDSMAEGTDLLDEIVTATTTESGDLEFVHSTPGPQALKPLPLVSQEEGIVVVEQAVQTDVVPFSPAISELLQSVLKLQDSCPTSSASPDESGADSMESFSESISALMVDLTPRSPNSAILLSPVEIPFSKAATEARANRLMRELDFAACTEERLDSILSLSQGGVVRQYWSSSFLVDLLAVAAPVVPTVLWVFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFHMKT", "length": 788 }, "evidence": [ { "id": "A0A1D5NVV7", "url": "https://omabrowser.org/oma/group/A0A1D5NVV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SQA3-1", "protein_name": "Syntabulin", "gene_name": "SYBU", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLCQACSSGLPGVRVGADPPRLSGEVPPPGRRQRRREEPAGGSAMGPLRETKKELRVQHHEKEIARSRIPRLILRPHLPQQQHKVSPASESPFSEEESREFNPSSSGRSARTVSSNSFCSDDTGCPSSQSVSPVKTPSDAGNSPIGFCPGSDEDCTRKKCTIGMVGEGSLQSARHKKEPKSGLVKPAHRVRCVSRAQSTLVNLNSKGSEADFSSSSSTGSISAPEVPMSAAGSKRSSFSRNRGPHGRSNGASSYKSANSPPSPREKDLLAMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPVMRRSGRYMSCGENHGVKPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGLLRDELCLDFPCESPEKGLALGAALGPTEGALSPEEPATEEGADSELLGADGAAPGEDVLEELVTGAIPEPELPGAEVVALGGEAAAVGRGGRRAVAERAVQTDVVPYSPAFSELLRHVLRLQDPWPSSSAATPDEESGDDSTESFPEPISTFVVDLTPRNPNSAILLSPVETPSPAAGPEARGNRLMRELDFAGSEAAAAEEEVRLDGPGPLARAGGIAGRYWSRSFLVDLLAVGAPVVPTVLWAFSTQRGGTDPLYNIGALLRGCCVVALHSLRRTTEHIKT", "length": 730 }, "evidence": [ { "id": "A0A1D5NVV7", "url": "https://omabrowser.org/oma/group/A0A1D5NVV7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHS8-1", "protein_name": "Syntabulin", "gene_name": "Sybu", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPLRESKKEQRVQHQEKEISRSRIPRLILRPHRPQQQQQQQNKVSPASESPFSEEESREFNPSSSGRSARTISSNSFCSDDTGCPSSQSVSPVKTPSDTGHSPIGFCPGSDEDFTRKKCRIGMVGEGSIQSARHKKEPKGGIIKPGSEADFSSSSSTGSISAPEVHMSTTGNKRASFSRNRGPHGRSNGASSHKSGSSPPSPREKDLVSMLCRNPLSPSNIHPSYAPSSPSSSNSGSYKGSDCSPVMRRSGRYMSCGENHGVKPPNPEQYLTPLQQKEVTVRHLRTKLKESERRLHERESEIMELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHNSSLRDELCLDFSFDSPEKSLPLSSTFDKLPDGLSLEEQITEEGADSELLVGDSMAEGTDLLDEMVTATTTESSGLEFVHSTPGPQALKALPLVSHEEGIAVMEQAVQTDVVPFSPAISELIQSVLKLQDYCPTSSASPDESGADSMESFSESISALMLDLTPRSPNSAILLSPVEIPFSKGAMEAHANRLMRELDFAAYTEERLDSVLSLSQGSVVRQYWSSNFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFHMKT", "length": 665 }, "evidence": [ { "id": "A0A1D5NVV7", "url": "https://omabrowser.org/oma/group/A0A1D5NVV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX95-1", "protein_name": "Syntabulin", "gene_name": "SYBU", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLRESKKEHRVQHHDKEISRSRIPRLILRPHMPQQQHKVSPASESPFSEEESREFNPSSSGRSARTVSSNSFCSDDTGCPSSQSVSPVKTPSDAGNSPIGFCPGSDEGFTRKKCTIGMVGEGSIQSSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSHKPGSSPSSPREKDLLSMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSLEEQVTGEGADRELLVGDSIANSTDLFDEIVTATTTESGDLELVHSTPGANVLELLPIVMGQEEGSVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLSPVETPYANVDAEVHANRLMRELDFAACVEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT", "length": 663 }, "evidence": [ { "id": "A0A1D5NVV7", "url": "https://omabrowser.org/oma/group/A0A1D5NVV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synapse maturation", "id": "GO:0060074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060074", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" }, { "name": "axonal transport of mitochondrion", "id": "GO:0019896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019896", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NVV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NVV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 658, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NVV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NVV7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 587, "end_pos": 589 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NWN7-1", "uniprot_ac": "A0A1D5NWN7", "uniprot_id": "A0A1D5NWN7_CHICK", "mass": { "chemical_mass": 30074.0, "monoisotopic_mass": 30074.0 }, "refseq": { "ac": "XP_015128097", "name": "transmembrane protein 106C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097" }, "gene_names": [ { "name": "TMEM106C", "type": "recommended", "evidence": [ { "id": "A0A1D5NWN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7" } ] }, { "name": "TMEM106C", "type": "synonym", "evidence": [ { "id": "XP_015128097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097" } ] } ], "protein_names": [ { "name": "Transmembrane protein 106C", "type": "synonym", "evidence": [ { "id": "A0A1D5NWN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 106C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015128097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM106C", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7", "locus": { "chromosome": "34", "start_pos": 1138644, "end_pos": 1132709, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024420", "url": "https://www.ensembl.org/id/ENSGALG00010024420" } ] } } ], "crossref": [ { "id": "A0A1D5NWN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034069", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034069", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426186", "url": "https://www.ncbi.nlm.nih.gov/gene/426186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426186", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NWN7", "url": "https://www.orthodb.org/?gene=A0A1D5NWN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28556", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28556", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28556:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28556:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSALSLSANSAASRRRRKAEDAADGDDDLLDSRDRNEDIAKFPYVEFTGQDSITCPTCQGTGCIPTEQVNELVALIPYSDQRLRPQRTKLYVLLSVLLCLLISGLVVFFLFPHSVLVDDGGIKVVQVWFDRKNSVVLLAITATLRIRNSNFYSVTVDSLTSQVQYMNTVVGSQQITNISSIQPLSDKLVNFTVKAEMGGPFSYVYFFCTFPKVKVHNIVIFMRTSVKLSYIGRRTQSSVETYHYIDCSTNSTADPPPLPAPSTHGVALSKP", "length": 272, "header": "tr|A0A1D5NWN7-1|A0A1D5NWN7_CHICK Isoform 1 of Transmembrane protein 106C OS=Gallus gallus OX=9031 GN=TMEM106C PE=1 SV=1 CANONICAL=A0A1D5NWN7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7/entry", "sequence": { "sequence": "MGSALSLSANSAASRRRRKAEDAADGDDDLLDSRDRNEDIAKFPYVEFTGQDSITCPTCQGTGCIPTEQVNELVALIPYSDQRLRPQRTKLYVLLSVLLCLLISGLVVFFLFPHSVLVDDGGIKVVQVWFDRKNSVVLLAITATLRIRNSNFYSVTVDSLTSQVQYMNTVVGSQQITNISSIQPLSDKLVNFTVKAEMGGPFSYVYFFCTFPKVKVHNIVIFMRTSVKLSYIGRRTQSSVETYHYIDCSTNSTADPPPLPAPSTHGVALSKP", "length": 272, "header": "tr|A0A1D5NWN7-1|A0A1D5NWN7_CHICK Isoform 1 of Transmembrane protein 106C OS=Gallus gallus OX=9031 GN=TMEM106C PE=1 SV=1 CANONICAL=A0A1D5NWN7-1" }, "locus": { "chromosome": "34", "start_pos": 1135923, "end_pos": 1133423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059576.1", "url": "https://www.ensembl.org/id/ENSGALT00010059576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036380.1", "url": "https://www.ensembl.org/id/ENSGALP00010036380.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426186", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NWN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 272, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NWN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NWN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7" }, { "id": "PF07092", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 106 C-terminal", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 253, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5NWN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWN7" }, { "id": "PF21002", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 106 N-terminal", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 90, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NWQ1-1", "uniprot_ac": "A0A1D5NWQ1", "uniprot_id": "A0A1D5NWQ1_CHICK", "mass": { "chemical_mass": 35068.0, "monoisotopic_mass": 35068.0 }, "refseq": { "ac": "XP_015152658", "name": "solute carrier family 25 member 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658" }, "gene_names": [ { "name": "SLC25A34", "type": "recommended", "evidence": [ { "id": "A0A1D5NWQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1" } ] }, { "name": "SLC25A34", "type": "synonym", "evidence": [ { "id": "XP_015152658", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 34", "type": "recommended", "evidence": [ { "id": "A0A1D5NWQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 member 34", "type": "synonym", "evidence": [ { "id": "XP_015152658", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A34", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1", "locus": { "chromosome": "21", "start_pos": 4220672, "end_pos": 4218750, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021797", "url": "https://www.ensembl.org/id/ENSGALG00010021797" } ] } } ], "crossref": [ { "id": "A0A1D5NWQ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033034", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033034", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107054933", "url": "https://www.ncbi.nlm.nih.gov/gene/107054933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107054933", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KANCEDH", "url": "https://omabrowser.org/oma/group/KANCEDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWQ1", "url": "https://www.orthodb.org/?gene=A0A1D5NWQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45928:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45928:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGTGALGPFPAAALHDFPYPSQTAAPVSHGPPAGGVPPAADLVLGAAAGCMACVLTNPLEVVKTRLQLQGELRAPGTYPRPYRGVLRAVGAVCRADGLRGLQKGLAAGLLYQGLMNGVRFYCYSCALDAGWTGWPGGTVVAGAVAGAVGAFVGSPAYLVKTHLQAQTLSAMAVGHQHNHESISDAFGSIYRQHGVAGLWRGVSGAVPRVAVGSAAQLATFASAKDWVCQHQWFGEGSWAAVLAGGMVSGVAVAVTMTPFDVVSTRLYNQPVEADGTGKLYRGFLDCFAQISSKEGLLGLYKGIGAVYLRLGPHTVLSLFFWDELRRMVRPQPPPGP", "length": 338, "header": "tr|A0A1D5NWQ1-1|A0A1D5NWQ1_CHICK Isoform 1 of Solute carrier family 25 member 34 OS=Gallus gallus OX=9031 GN=SLC25A34 PE=3 SV=3 CANONICAL=A0A1D5NWQ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1/entry", "sequence": { "sequence": "MAAGTGALGPFPAAALHDFPYPSQTAAPVSHGPPAGGVPPAADLVLGAAAGCMACVLTNPLEVVKTRLQLQGELRAPGTYPRPYRGVLRAVGAVCRADGLRGLQKGLAAGLLYQGLMNGVRFYCYSCALDAGWTGWPGGTVVAGAVAGAVGAFVGSPAYLVKTHLQAQTLSAMAVGHQHNHESISDAFGSIYRQHGVAGLWRGVSGAVPRVAVGSAAQLATFASAKDWVCQHQWFGEGSWAAVLAGGMVSGVAVAVTMTPFDVVSTRLYNQPVEADGTGKLYRGFLDCFAQISSKEGLLGLYKGIGAVYLRLGPHTVLSLFFWDELRRMVRPQPPPGP", "length": 338, "header": "tr|A0A1D5NWQ1-1|A0A1D5NWQ1_CHICK Isoform 1 of Solute carrier family 25 member 34 OS=Gallus gallus OX=9031 GN=SLC25A34 PE=3 SV=3 CANONICAL=A0A1D5NWQ1-1" }, "locus": { "chromosome": "21", "start_pos": 4220628, "end_pos": 4218796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053022.1", "url": "https://www.ensembl.org/id/ENSGALT00010053022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031928.1", "url": "https://www.ensembl.org/id/ENSGALP00010031928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107054933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054933", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MUF0-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "Slc25a34", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPTMDAEDMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNSVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAALAVGHQHQHQSVLGALETIWRQQGLLGLWRGVGGAVPRVTVGSAAQLATFASAKAWVQERQWFLEDSWLVTLTGGMISSIAVAAVMTPFDVVSTRLYNQPVDRAGRGQLYGGLADCLVKICQQEGPLALYKGLGLAYLRLGPHTILSMFFWDELRKLAARAQR", "length": 308 }, "evidence": [ { "id": "A0A1D5NWQ1", "url": "https://omabrowser.org/oma/group/A0A1D5NWQ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2ADF7-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "Slc25a34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPTQAQMAPAMDSREMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAAAGALGAFVGSPAYLVKTQLQAQTVATMAVGHQHQHQGVLSALETIWRQQGMLGLWRGVGGAVPRVTVGSAAQLATFTSAKAWVQDRQWFLEDSWLVTLAGGMISSIAVVAVMTPLDVVSTRLYNQPVDRAGRGQLYGGLADCLVKTCQQEGPLALYKGLGPAYLRLGPHTILSMFFWDELRKLVARAQHQGT", "length": 318 }, "evidence": [ { "id": "A0A1D5NWQ1", "url": "https://omabrowser.org/oma/group/A0A1D5NWQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SZK0-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQKRGTYPRLYRGFVASVVAVVRADGLCGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLSQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAAMAVGHQHHHESLLGALETIWRQQGLAGLWRGVGGAVPRVMVGSAAQLATFASAKAWVQERQWLPEDSWLVALAGGMISSIAVVAVMTPFDVVSTRLYNQPVDGAGRGKLYGGLTDCLVKIWRQEGPLALYKGLGPVYLRLGPHTILSMLFWDELRKLAGWGQHQGS", "length": 304 }, "evidence": [ { "id": "A0A1D5NWQ1", "url": "https://omabrowser.org/oma/group/A0A1D5NWQ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PIV7-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAGRAQHKGT", "length": 304 }, "evidence": [ { "id": "A0A1D5NWQ1", "url": "https://omabrowser.org/oma/group/A0A1D5NWQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NWQ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 338, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NWQ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWQ1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NWW5-1", "uniprot_ac": "A0A1D5NWW5", "uniprot_id": "A0A1D5NWW5_CHICK", "mass": { "chemical_mass": 43471.0, "monoisotopic_mass": 43471.0 }, "refseq": { "ac": "XP_003640604", "name": "Krueppel-like factor 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604" }, "gene_names": [ { "name": "KLF12", "type": "recommended", "evidence": [ { "id": "A0A1D5NWW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ] }, { "name": "KLF12", "type": "synonym", "evidence": [ { "id": "XP_003640604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604" } ] } ], "protein_names": [ { "name": "KLF transcription factor 12", "type": "synonym", "evidence": [ { "id": "A0A1D5NWW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003640604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF12", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5", "locus": { "chromosome": "1", "start_pos": 155796575, "end_pos": 155542000, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000818", "url": "https://www.ensembl.org/id/ENSGALG00010000818" } ] } } ], "crossref": [ { "id": "A0A1D5NWW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016926", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016926", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21441", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21441", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418817", "url": "https://www.ncbi.nlm.nih.gov/gene/418817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418817", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNNAMML", "url": "https://omabrowser.org/oma/group/LNNAMML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWW5", "url": "https://www.orthodb.org/?gene=A0A1D5NWW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGB9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRKAIKDVSAFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNMKADPPEDSLSADHFQTQTEPVDLSINKARSSPTAASSSPVSMTASASSPSSTSTSSSSSRPASSPTVITSVSSAASVPSVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKMSHVHRIPVVVQSVPVVYTAVRSPGNMNNTIVVPLLEDGRSHVKAQMDPRGLSPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEESMWGCARSAANPFRFFNSSSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 396, "header": "tr|A0A1D5NWW5-1|A0A1D5NWW5_CHICK Isoform 1 of KLF transcription factor 12 OS=Gallus gallus OX=9031 GN=KLF12 PE=4 SV=2 CANONICAL=A0A1D5NWW5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5/entry", "sequence": { "sequence": "MKRKAIKDVSAFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNMKADPPEDSLSADHFQTQTEPVDLSINKARSSPTAASSSPVSMTASASSPSSTSTSSSSSRPASSPTVITSVSSAASVPSVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKMSHVHRIPVVVQSVPVVYTAVRSPGNMNNTIVVPLLEDGRSHVKAQMDPRGLSPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEESMWGCARSAANPFRFFNSSSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 396, "header": "tr|A0A1D5NWW5-1|A0A1D5NWW5_CHICK Isoform 1 of KLF transcription factor 12 OS=Gallus gallus OX=9031 GN=KLF12 PE=4 SV=2 CANONICAL=A0A1D5NWW5-1" }, "locus": { "chromosome": "1", "start_pos": 155795855, "end_pos": 155615643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001810.1", "url": "https://www.ensembl.org/id/ENSGALT00010001810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001011.1", "url": "https://www.ensembl.org/id/ENSGALP00010001011.1" } ] } }, { "isoform_ac": "A0A3Q2UGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGB9/entry", "sequence": { "sequence": "MKRKAIKDVSAFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNMKADPPEDSLSADHFQTQTEPVDLSINKARSSPTAASSSPVSMTASASSPSSTSTSSSSSRPASSPTVITSVSSAASVPSVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKMSHVHRIPVVVQSVPVVYTAVRSPGNMNNTIVVPLLEDGRSHVKAQMDPRGLSPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQDSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 376, "header": "tr|A0A3Q2UGB9-1|A0A3Q2UGB9_CHICK Computationally mapped isoform of KLF transcription factor 12 OS=Gallus gallus OX=9031 GN=KLF12 PE=4 SV=1 CANONICAL=A0A1D5NWW5-1" }, "locus": { "chromosome": "1", "start_pos": 155795855, "end_pos": 155615643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001811.1", "url": "https://www.ensembl.org/id/ENSGALT00010001811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001012.1", "url": "https://www.ensembl.org/id/ENSGALP00010001012.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K610-1", "protein_name": "KLF transcription factor 12", "gene_name": "Klf12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIHTKRKIIKNLTTLENRMLMFDGMPAVRVKTELLESEQGSPNVHNYPDMEAIPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGMGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 402 }, "evidence": [ { "id": "A0A1D5NWW5", "url": "https://omabrowser.org/oma/group/A0A1D5NWW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35738-1", "protein_name": "Krueppel-like factor 12", "gene_name": "Klf12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIHMKRKTIKNLSALENRMLMLDGMPAVRVKTELVESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 402 }, "evidence": [ { "id": "A0A1D5NWW5", "url": "https://omabrowser.org/oma/group/A0A1D5NWW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4X4-1", "protein_name": "Krueppel-like factor 12", "gene_name": "KLF12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIHMKRKTIKNINTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "length": 402 }, "evidence": [ { "id": "A0A1D5NWW5", "url": "https://omabrowser.org/oma/group/A0A1D5NWW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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The reference sequence was derived from JAENSK010000044.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWY4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWY4", "locus": { "chromosome": "2", "start_pos": 137108059, "end_pos": 137115226, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008250", "url": "https://www.ensembl.org/id/ENSGALG00010008250" } ] } } ], "crossref": [ { "id": "A0A1D5NWY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWY4", "database": "AlphaFoldDB", 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"https://www.ncbi.nlm.nih.gov/protein/XP_418303" }, "gene_names": [ { "name": "GDAP1", "type": "recommended", "evidence": [ { "id": "A0A1D5NWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ] }, { "name": "GDAP1", "type": "synonym", "evidence": [ { "id": "XP_418303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418303" } ] } ], "protein_names": [ { "name": "Ganglioside-induced differentiation-associated protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5NWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6/entry#names_and_taxonomy" } ] }, { "name": "ganglioside-induced differentiation-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418303" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418303.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418303" } ] }, { "annotation": "Regulates the mitochondrial network by promoting mitochondrial fission.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6#function" }, { "database": "UniProtKB", "id": "ARBA00059649", "url": "https://www.uniprot.org/uniprotkb/ARBA00059649#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GDAP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6", "locus": { "chromosome": "2", "start_pos": 117933158, "end_pos": 117923192, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003528", "url": "https://www.ensembl.org/id/ENSGALG00010003528" } ] } } ], "crossref": [ { "id": "A0A1D5NWZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042798", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042798", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420191", "url": "https://www.ncbi.nlm.nih.gov/gene/420191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LHCEEYD", "url": "https://omabrowser.org/oma/group/LHCEEYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWZ6", "url": "https://www.orthodb.org/?gene=A0A1D5NWZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44188:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44188:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPGGAAAPLVLYHWTQSFSSQKVRLAIAEKALTCEEHDVNLPLSEHNEPWFMRLNASGEVPVLIHGENIICEATQIIDYLEATFVDAEVPRLMPEEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATSRIRSQISNTESELKKLAEENPDLQDAYIAKQKRLKSKLLDHDNIKYLKKILDELEKVLDQVETELQRRNEETPEDGSQPWLCGEFFSLADVSLAVTLHRLKFLGLARRNWGNGKRPNLEAYYERVLKRKAFHKVLGHVNNILISAVLPTAFRVAKKRAPRVLGTTLMVGMLAGMAYFALVCLRKRFANMMLSIRTRQNYF", "length": 343, "header": "tr|A0A1D5NWZ6-1|A0A1D5NWZ6_CHICK Isoform 1 of Ganglioside-induced differentiation-associated protein 1 OS=Gallus gallus OX=9031 GN=GDAP1 PE=3 SV=1 CANONICAL=A0A1D5NWZ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6/entry", "sequence": { "sequence": "MAGPGGAAAPLVLYHWTQSFSSQKVRLAIAEKALTCEEHDVNLPLSEHNEPWFMRLNASGEVPVLIHGENIICEATQIIDYLEATFVDAEVPRLMPEEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATSRIRSQISNTESELKKLAEENPDLQDAYIAKQKRLKSKLLDHDNIKYLKKILDELEKVLDQVETELQRRNEETPEDGSQPWLCGEFFSLADVSLAVTLHRLKFLGLARRNWGNGKRPNLEAYYERVLKRKAFHKVLGHVNNILISAVLPTAFRVAKKRAPRVLGTTLMVGMLAGMAYFALVCLRKRFANMMLSIRTRQNYF", "length": 343, "header": "tr|A0A1D5NWZ6-1|A0A1D5NWZ6_CHICK Isoform 1 of Ganglioside-induced differentiation-associated protein 1 OS=Gallus gallus OX=9031 GN=GDAP1 PE=3 SV=1 CANONICAL=A0A1D5NWZ6-1" }, "locus": { "chromosome": "2", "start_pos": 117929884, "end_pos": 117923408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008231.1", "url": "https://www.ensembl.org/id/ENSGALT00010008231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004891.1", "url": "https://www.ensembl.org/id/ENSGALP00010004891.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QQZ0-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARRQDEQRGGAPLIAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGMGYFAFMLFRKRLGSMILALRPRPNYF", "length": 358 }, "evidence": [ { "id": "A0A1D5NWZ6", "url": "https://omabrowser.org/oma/group/A0A1D5NWZ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A5X7-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "Gdap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSQGPLPTRQHSFLGVKLHLPEASSSAKHVLYATGGPAKPKDGSKPLQQAGQPTRLAESLHPAMARKQDEARSGVPLRAQGPPAAEVRLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRGQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPDEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLESYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGNMILSLRPRPNYF", "length": 422 }, "evidence": [ { "id": "A0A1D5NWZ6", "url": "https://omabrowser.org/oma/group/A0A1D5NWZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RWK1-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARRQDEQRGGAPLMAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGEPFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLFAGMGYFAFMLFRKRLGNMILALRPRPNYF", "length": 358 }, "evidence": [ { "id": "A0A1D5NWZ6", "url": "https://omabrowser.org/oma/group/A0A1D5NWZ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88741-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "Gdap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRQDEARAGVPLRVEGPPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGSMILALRPRPNYF", "length": 358 }, "evidence": [ { "id": "A0A1D5NWZ6", "url": "https://omabrowser.org/oma/group/A0A1D5NWZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB36-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERQEEQRGSPPLRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF", "length": 358 }, "evidence": [ { "id": "A0A1D5NWZ6", "url": "https://omabrowser.org/oma/group/A0A1D5NWZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein targeting to mitochondrion", "id": "GO:0006626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NWZ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 343, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NWZ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NWZ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NX23-1", "uniprot_ac": "A0A1D5NX23", "uniprot_id": "A0A1D5NX23_CHICK", "mass": { "chemical_mass": 104882.0, "monoisotopic_mass": 104882.0 }, "refseq": { "ac": "XP_004943836", "name": "zinc finger protein 280D isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836" }, "gene_names": [ { "name": "ZNF280D", "type": "recommended", "evidence": [ { "id": "A0A1D5NX23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ] }, { "name": "ZNF280D", "type": "synonym", "evidence": [ { "id": "XP_004943836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836" } ] } ], "protein_names": [ { "name": "Zinc finger protein 280D", "type": "synonym", "evidence": [ { "id": "A0A1D5NX23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 280D isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004943836.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836" } ] }, { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF280D", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23", "locus": { "chromosome": "10", "start_pos": 7658547, "end_pos": 7610932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023201", "url": "https://www.ensembl.org/id/ENSGALG00010023201" } ] } } ], "crossref": [ { "id": "A0A1D5NX23", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NX23", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037723", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037723", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415593", "url": "https://www.ncbi.nlm.nih.gov/gene/415593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415593", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDANAFE", "url": "https://omabrowser.org/oma/group/CDANAFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NX23", "url": "https://www.orthodb.org/?gene=A0A1D5NX23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A8D2", "url": "https://www.orthodb.org/?gene=A0A3Q3A8D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTW4", "url": "https://www.orthodb.org/?gene=A0A8V0ZTW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUY9", "url": "https://www.orthodb.org/?gene=A0A8V0ZUY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV05", "url": "https://www.orthodb.org/?gene=A0A8V0ZV05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZE5", "url": "https://www.orthodb.org/?gene=A0A8V0ZZE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NX23-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A8D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A8D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A8D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A8D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELFMECEEEELEPWQKRVKEVEEDDDDDEPIFIGEISSSKPASTYILNRINFSSSRRQIQNGAPSRGTVTSFKSDSHHYVTPASSPSAIPVSSVFQSVSRSTASSVAVQPLSRPVNVSGASQTLQRPVAGCLSTQQMTRSSSGPSQPVSRPVTIPVTTQPVSRNITVPLVAQPVSRPLTTVTTQPIILNQDYIMDSPPDAPDNTSGILFGVRQNSGVPQYQTEPTVSVTDTNTASSNIKNGGPFPRACPKCNIHFNLMDPLKNHMKYCCPDLVNDFFLGVVQTECSTATSKTTEYEKGKLIMLVNDFYYGKHEGDTQQVQQEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSESWESHTTCQHCYRQFPTPFQLQCHIESTHTPYESSTICKICELSFETEQVLLQHMKDNHKPGEMPYVCQVCNYRSSAFSDVETHFRTVHENTKHLLCPFCLKVIKIGAPYMHHYMRHQKKGIYRCTKCRLQFLTCKEKMDHKTQHHRTFRKPKQLEGLPPGTKVTIRASIGSLQSGSSVSTSTSTFQLSPKAKNTTARNHSRSNSNKSKARSKPTTTLKKQNAWTNSSSKKKKVTNTALHNLRCRLGAHKCIECYSEIKDFASHFPAYVHCSLCRYNTSCSKAYVNHMMSFHSARPSKRFWIYKKHSEDLRGVTVVCLNCDFLTDGSGLDRMATHLSESHTHACQVIIENVSVDLPTAEQVSDKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 935, "header": "tr|A0A1D5NX23-1|A0A1D5NX23_CHICK Isoform 1 of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=2 CANONICAL=A0A1D5NX23-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NX23-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23/entry", "sequence": { "sequence": "MAELFMECEEEELEPWQKRVKEVEEDDDDDEPIFIGEISSSKPASTYILNRINFSSSRRQIQNGAPSRGTVTSFKSDSHHYVTPASSPSAIPVSSVFQSVSRSTASSVAVQPLSRPVNVSGASQTLQRPVAGCLSTQQMTRSSSGPSQPVSRPVTIPVTTQPVSRNITVPLVAQPVSRPLTTVTTQPIILNQDYIMDSPPDAPDNTSGILFGVRQNSGVPQYQTEPTVSVTDTNTASSNIKNGGPFPRACPKCNIHFNLMDPLKNHMKYCCPDLVNDFFLGVVQTECSTATSKTTEYEKGKLIMLVNDFYYGKHEGDTQQVQQEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSESWESHTTCQHCYRQFPTPFQLQCHIESTHTPYESSTICKICELSFETEQVLLQHMKDNHKPGEMPYVCQVCNYRSSAFSDVETHFRTVHENTKHLLCPFCLKVIKIGAPYMHHYMRHQKKGIYRCTKCRLQFLTCKEKMDHKTQHHRTFRKPKQLEGLPPGTKVTIRASIGSLQSGSSVSTSTSTFQLSPKAKNTTARNHSRSNSNKSKARSKPTTTLKKQNAWTNSSSKKKKVTNTALHNLRCRLGAHKCIECYSEIKDFASHFPAYVHCSLCRYNTSCSKAYVNHMMSFHSARPSKRFWIYKKHSEDLRGVTVVCLNCDFLTDGSGLDRMATHLSESHTHACQVIIENVSVDLPTAEQVSDKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 935, "header": "tr|A0A1D5NX23-1|A0A1D5NX23_CHICK Isoform 1 of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=2 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7615838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056548.1", "url": "https://www.ensembl.org/id/ENSGALT00010056548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034290.1", "url": "https://www.ensembl.org/id/ENSGALP00010034290.1" } ] } }, { "isoform_ac": "A0A3Q3A8D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A8D2/entry", "sequence": { "sequence": "TQSSLGLFCKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 219, "header": "tr|A0A3Q3A8D2-1|A0A1D5NX23_CHICK Computationally mapped isoform of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=1 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7643229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056541.1", "url": "https://www.ensembl.org/id/ENSGALT00010056541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034283.1", "url": "https://www.ensembl.org/id/ENSGALP00010034283.1" } ] } }, { "isoform_ac": "A0A8V0ZTW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTW4/entry", "sequence": { "sequence": "EICNATLGVTLRSIATCCCIITFRKIIFCFFSKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 242, "header": "tr|A0A8V0ZTW4-1|A0A1D5NX23_CHICK Computationally mapped isoform of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=1 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7654572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056533.1", "url": "https://www.ensembl.org/id/ENSGALT00010056533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034275.1", "url": "https://www.ensembl.org/id/ENSGALP00010034275.1" } ] } }, { "isoform_ac": "A0A8V0ZUY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUY9/entry", "sequence": { "sequence": "RLKSPLERKKLSWSKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 224, "header": "tr|A0A8V0ZUY9-1|A0A1D5NX23_CHICK Computationally mapped isoform of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=1 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7648452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056537.1", "url": "https://www.ensembl.org/id/ENSGALT00010056537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034279.1", "url": "https://www.ensembl.org/id/ENSGALP00010034279.1" } ] } }, { "isoform_ac": "A0A8V0ZV05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV05/entry", "sequence": { "sequence": "PARPPSFPRRRLRWGAAVRRCEAASPARLLPSPPAGPAARSGAARRGSSGRGARKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 264, "header": "tr|A0A8V0ZV05-1|A0A1D5NX23_CHICK Computationally mapped isoform of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=1 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7610933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056553.1", "url": "https://www.ensembl.org/id/ENSGALT00010056553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034295.1", "url": "https://www.ensembl.org/id/ENSGALP00010034295.1" } ] } }, { "isoform_ac": "A0A8V0ZZE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE5/entry", "sequence": { "sequence": "MYESKQGLDSSEETKEGNRNQNEVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRCDSDHHKQLVGEKQKCIHGESELKTCQSSDYVVLTDQTKVQNLDKTTLSAMNARDLKLTLGEDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIAPSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS", "length": 214, "header": "tr|A0A8V0ZZE5-1|A0A1D5NX23_CHICK Computationally mapped isoform of Zinc finger protein 280D OS=Gallus gallus OX=9031 GN=ZNF280D PE=4 SV=1 CANONICAL=A0A1D5NX23-1" }, "locus": { "chromosome": "10", "start_pos": 7655297, "end_pos": 7650740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056535.1", "url": "https://www.ensembl.org/id/ENSGALT00010056535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034277.1", "url": "https://www.ensembl.org/id/ENSGALP00010034277.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415593", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QIB6-1", "protein_name": "Zinc finger protein 280D isoform X1", "gene_name": "Znf280d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDCSFQPKDNLKMAELFMECEEEELEPWQKKVKEVEEDDDDEPIFVAEIASSKPAISNILNRVNSSSRGIKNGALNRGFTTSFKPTSQRFPNPASNPVAALPVNFHPDSRSSDCSVIVQSFSKPGYVTNSPTVLSNNSSELLFDLTQDTGLSHYPAAPALSIAGLNESSFSSKRPFSDISSVNSKKPKPSDNISGADASSVLSSEKPPSVLSLQVAPLQGANCSSNQSKNGTTFPRACPKCNIHFNLLDPLKKHMTYCCPDMINNFLGLNKIEISNTANEAKTLDSEKGKLIMLVNDFYYGKHEGDVQEEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLHDFSTICKICELSFETEQNLLQHMKDNHKPGEMPYICQVCNYRSSLFSDVESHFKTAHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFVKPKQLEGLPPGTKVTIRASVGPLQSGPSATPSISDASTSTLQLSPPRTENVTSKNPTTLDTSTQNTTVSEPSKPNESKSNGNKSKNRSKVCNTQKKQSTVANSNKKSKVNTALRNLRLRRGVHECIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRFCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKVSVCIPTSERLSELKTEAPTKGQESVSKETARHNTAEGETGASPSEGKQNKAPSSEGSIGRDASVCEAAAAAADCEGNVAVSDTENESRSKSIFSHGSDAGAENMRKEEQTQHTCQEMELKVHQSSEHMDSWDQTKEHDSPAADFPSETGQDSQLTSGVAGIDQFLRQREKPESVSSDASEQGSVGLEPLTPSEVLEYEATEMLHKDDNSSANSNDTVSDETGGSPGGSRAETAVDLAEGKERS", "length": 967 }, "evidence": [ { "id": "A0A1D5NX23", "url": "https://omabrowser.org/oma/group/A0A1D5NX23/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LVH6-1", "protein_name": "Zinc finger protein 280D", "gene_name": "Zfp280d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVGNRRTWVLQKSNNLKMAELFMECEEEELEPWQKKVKEVEEDDDDEPIFVAEIASSKPAISNILNRVNPSSHSRGIKNGILNRGFTASFKPTSQRCPNSASNPVAALPVNFHPESRSSDSSVIVQPFSKPGYVTNSPRVLSSNPSELLFDLTQDTGLSHYQGGPTLSIAGLNETSFLSKRPSGSDISSVNPKKPKPNENISGTDASSVVSSEKSPSVMSLQVVPSQGTNCSSNQSKNGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLTKTDNLNSANEAKTLDSEKGKLIMLVNDFYYGKYEGDVQEEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPHEFSTICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSSLFSEVESHFRTSHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFVKPKQLEGLPPGTKVTIRASVAPLQSGSSVTPSISASTSTLQLSPPRTENVTAKNHVKLNTSTPNTTISDPSKTNEIKSNGSKSKNRSKVSNMQKKQSTLSNSNKKSKVNTALRNLRLRRGVHECIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRYCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHTCQVLVEKVSVCIPTSERLSELKTEAPTKGQESVSKETARHSTAEREPGASHSESKQDKAPPSEDDTGRDASVCEAAAAANRERNVTASDTEDVRTSNDVLSRGPEVGTDNMEKEEQAHHTCQEMELKRDQSSESTDDQSKEHSPTEAELSSEISQDLQLTPEGVGLGQCLRQGEEPESVNSDASEQDSVRLEPLTPSEVLEFEATEVCHSGEDPSASTSDAVSGGTGGSPGGSSPRRAESAADLAGGQEGS", "length": 974 }, "evidence": [ { "id": "A0A1D5NX23", "url": "https://omabrowser.org/oma/group/A0A1D5NX23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LEU1-1", "protein_name": "Zinc finger protein 280D", "gene_name": "ZNF280D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAELFMECEEEELEPWQKKVKEVDDDDDDEPIFVGEISGSKPAISNILNRVNPSSYSRGIKNGALSRGITAAFKSTSQHYTNPTSNPVAASPVNFHPESRSSDSSVIVQPLSKPGYITNSSRVVTNNSSELLFDLTQDTGLPHYQGGTTLSIAGINESSFLSKRPSTSEVNSVNPKKSKPSEGVSGTNSSAVLSSVKSLSVTSSQAMPSKGTNTSSNQSKNGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLAKTEFSSTANKNKTIDSEKGKLIMLVNDFYYGKHEGDVQEEQKTYTTFKCFSCLKILKNNIRFMNHMKHHLELEKQSSESWENHTTCQHCYRQFPTPFQLQCHIESTHTPHEFSTICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSSSFSDVETHFRTSHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFIKPKQLEGLPPGTKVTIRASVGPLQSGSSTTPSISASTSTLQLSPPRTKNITAKNPAKSNTSKPNITKSIASKPNTSKPNGSKPKYKSKISNMQKKQSTLASSNKKSKVNTALRNLRYRRGVHKCIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRFCIFKKYSEDLRGITLVCLNCDFLADVSGLDNMATHLSLHETHTCQVVIEKVSVCIPTSEHLSELKNQAPTKEQVPVSEEIARPNMAEGETETSSSESKQDEASSEEIKNGCNAHLFEGPSTTKSEEGMSVSDKENDTCLEDQETGSKHVFSYDSVTDADKVEKEKQIEHICQETKLKMCRSSENIIACDQIEECNASEARLSLKNIKDLRLTSGDVSIDQFLRKRDEPGSVSSDVSEQGSVHLEPLTPSEVLEYEATEILHKGSGDPSAKTDEVVSDHTDVPGENSLSTTETSGDLADEKERRS", "length": 966 }, "evidence": [ { "id": "A0A1D5NX23", "url": "https://omabrowser.org/oma/group/A0A1D5NX23/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q68FE8-1", "protein_name": "Zinc finger protein 280D", "gene_name": "Znf280d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVTTYIKSDLQLDGRQFFQPKDNLKMAELFMECEEEELEPWQKKVKEVEEDDDDEPIFVAEIASSKPAISNILNRVNPSSHSRGIKNGILNRGFTASFKPTSQRCLNSASNPVAALPVNFHPESRSSDSSVIVQPFSKPGYVTNSPRVLSNNSSELLFDLTQDTGLSHYQGGPTLSIAGLNETSFLSKRPSGSDISSVNPKKPKPSENTSGIDASSVISSEKSPSVISLQVVPSQGANCSSSQSKNGTTFPRACPKCDIHFNLLDPLKNHMTYCCPDMINNFLGLTKADNLNSANEAKTLESEKGKLIMLVNDFYYGKHEGDVLEEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPHEFSTICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSSLFSEVESHFRTSHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVTPSISPSTSTLQLSPPEPDNVTAKNHVKLTTSTPNTTISDPSKANETKSNGSKSKNKSKVSNMQKKQSTLSSSNKKSKVNTALRNLRLRRGVHECIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRYCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHSCRVLVEQVSVCIPTSERLSEIKTEAPTKGQEPVSKETARHSRAEGEPGASHSGSKQDKVPSSEEGTGCDASVCEAAAATHCEKDVTVSDTENVSSSKNILSHDPDVGTDTMEKEEKTHHACQEMELKVDQSSESTNPTEAELSSETRQGLQLTSGDVGIDQFLRQGDEPKSVNSDASDPGSVRLEPLTPSEVLEYEATEILHDGDDPSANTSDTVSDQTGGSPGGSNPCRAETAVDLADGEERS", "length": 974 }, "evidence": [ { "id": "A0A1D5NX23", "url": "https://omabrowser.org/oma/group/A0A1D5NX23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 927, "end_pos": 929, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NX23-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 935, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NX23-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NX23" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NX23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX23" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 396, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 83 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 639, "end_pos": 641 }, { "start_pos": 712, "end_pos": 714 }, { "start_pos": 754, "end_pos": 756 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 927, "end_pos": 929 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NX74-1", "uniprot_ac": "A0A1D5NX74", "uniprot_id": "A0A1D5NX74_CHICK", "mass": { "chemical_mass": 158905.0, "monoisotopic_mass": 158905.0 }, "refseq": { "ac": "XP_025003955", "name": "protein FAM135B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003955" }, "gene_names": [ { "name": "FAM135B", "type": "recommended", "evidence": [ { "id": "A0A1D5NX74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74" } ] }, { "name": "FAM135B", "type": "synonym", "evidence": [ { "id": "XP_025003955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003955" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 135 member B", "type": "synonym", "evidence": [ { "id": "A0A1D5NX74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74/entry#names_and_taxonomy" } ] }, { "name": "protein FAM135B", "type": "synonym", "evidence": [ { "id": "XP_025003955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003955" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX74", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM135B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74", "locus": { "chromosome": "2", "start_pos": 143185332, "end_pos": 143369082, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008884", "url": "https://www.ensembl.org/id/ENSGALG00010008884" } ] } } ], "crossref": [ { "id": "ENSGALG00000039831", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039831", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428384", "url": "https://www.ncbi.nlm.nih.gov/gene/428384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428384", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428384", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HFHPRKG", "url": "https://omabrowser.org/oma/group/HFHPRKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NX74", "url": "https://www.orthodb.org/?gene=A0A1D5NX74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1A7", "url": "https://www.orthodb.org/?gene=A0A8V0Y1A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12482:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12482:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12394", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12394", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025003955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NX74", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NX74-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDSSLCSACVHENNIYSRIFQILYRNEEIILNESMNFRVHLLLDGERVEDALSEADFQLKLDLHFTDSEQQLRDVPAIPMISSRTLCLHFHPQRGLHHHVPVMFDYFHLSVISVTVHASLVALHQPLISFARPGKGSWLGKGNLDTGPDQSSMSLENLVFGAGYCKPTSSEGSFYVPSENCMQHAYKWHKDLCLLLLNAQRGLHVYYSLIMKEVPDLPQMKLEELPVEDTLSQFCAELQLLSNPEKIAEQISKDLAWLCSHLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEAFFYTEHNKLAVLTFQEGLIQSHAQISTEIRNSEYFTSMPPLPAECLEIDGDWNTLPVIFEDRYMDLPCKDQNLDTFPDFEVPANTQIDVIDEKENLASNDATVEMKGDFGKGTLLIHTDRINGNPCLYSDTEGAALAAKGLNQHSNSQVCTVNKEGQRKPENICVSSKETTSVSELSNTECVSEESKTCKEVLLKDSRHSVGITSEEKKSSNKGPHRSEPMLIVSAQLECGACGTDGLESRTEIHKTSESGHLENNFSSEPALSEFTRLERTPEPDSKPLHPVLKALPSHSLEVKLFAKEQRTEECEEFTLMSGVIKRSSSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEEERVVELTKLTKSVSAPQISSPEEPVEEVDISKHTEATSGDSGGYLKSCRERENGDGQLMTDFSVCQLTTESEQLEPRGPSKPSAEDSNGNIELQREEAKEDFSETYCSLECTKPSACNPLRDNDSEGQSLESNDGCSLKTPRANNYLDKSIDEFDKYITDPKDTSKLDSLKIEQDLYISVRKTGEDSFSQSIKLVPHICNPVSDPSETSTEFGSVQRECNNFLADDSLLVYTEMQGLQEIELNDSPAPADPAAESCQDKYPQELDNQEQKLVANGTGFHSVTMDGVALESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQAAFPITRQPLGSFGVVSSHSNDVDEDANERMLNFYQAKEKFKKEMKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPSGKLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNVIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPLIGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1420, "header": "tr|A0A1D5NX74-1|A0A1D5NX74_CHICK Isoform 1 of Family with sequence similarity 135 member B OS=Gallus gallus OX=9031 GN=FAM135B PE=3 SV=1 CANONICAL=A0A1D5NX74-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NX74-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74/entry", "sequence": { "sequence": "MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDSSLCSACVHENNIYSRIFQILYRNEEIILNESMNFRVHLLLDGERVEDALSEADFQLKLDLHFTDSEQQLRDVPAIPMISSRTLCLHFHPQRGLHHHVPVMFDYFHLSVISVTVHASLVALHQPLISFARPGKGSWLGKGNLDTGPDQSSMSLENLVFGAGYCKPTSSEGSFYVPSENCMQHAYKWHKDLCLLLLNAQRGLHVYYSLIMKEVPDLPQMKLEELPVEDTLSQFCAELQLLSNPEKIAEQISKDLAWLCSHLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEAFFYTEHNKLAVLTFQEGLIQSHAQISTEIRNSEYFTSMPPLPAECLEIDGDWNTLPVIFEDRYMDLPCKDQNLDTFPDFEVPANTQIDVIDEKENLASNDATVEMKGDFGKGTLLIHTDRINGNPCLYSDTEGAALAAKGLNQHSNSQVCTVNKEGQRKPENICVSSKETTSVSELSNTECVSEESKTCKEVLLKDSRHSVGITSEEKKSSNKGPHRSEPMLIVSAQLECGACGTDGLESRTEIHKTSESGHLENNFSSEPALSEFTRLERTPEPDSKPLHPVLKALPSHSLEVKLFAKEQRTEECEEFTLMSGVIKRSSSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEEERVVELTKLTKSVSAPQISSPEEPVEEVDISKHTEATSGDSGGYLKSCRERENGDGQLMTDFSVCQLTTESEQLEPRGPSKPSAEDSNGNIELQREEAKEDFSETYCSLECTKPSACNPLRDNDSEGQSLESNDGCSLKTPRANNYLDKSIDEFDKYITDPKDTSKLDSLKIEQDLYISVRKTGEDSFSQSIKLVPHICNPVSDPSETSTEFGSVQRECNNFLADDSLLVYTEMQGLQEIELNDSPAPADPAAESCQDKYPQELDNQEQKLVANGTGFHSVTMDGVALESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQAAFPITRQPLGSFGVVSSHSNDVDEDANERMLNFYQAKEKFKKEMKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPSGKLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNVIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPLIGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1420, "header": "tr|A0A1D5NX74-1|A0A1D5NX74_CHICK Isoform 1 of Family with sequence similarity 135 member B OS=Gallus gallus OX=9031 GN=FAM135B PE=3 SV=1 CANONICAL=A0A1D5NX74-1" }, "locus": { "chromosome": "2", "start_pos": 143308756, "end_pos": 143186578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021076.1", "url": "https://www.ensembl.org/id/ENSGALT00010021076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012084.1", "url": "https://www.ensembl.org/id/ENSGALP00010012084.1" } ] } }, { "isoform_ac": "A0A8V0Y1A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1A7/entry", "sequence": { "sequence": "MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDSSLCSACVHENNIYSRIFQILYRNEEIILNESMNFRVHLLLDGERVEDALSEADFQLKLDLHFTDSEQQLRDVPAIPMISSRTLCLHFHPQRGLHHHVPVMFDYFHLSVISVTVHASLVALHQPLISFARPGKGSWLGKGNLDTGPDQSSMSLENLVFGAGYCKPTSSELLSNPEKIAEQISKDLAWLCSHLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEAFFYTEHNKLAVLTFQEGLIQSHAQISTEIRNSEYFTSMPPLPAECLEIDGDWNTLPVIFEDRYMDLPCKDQNLDTFPDFEVPANTQIDVIDEKENLASNDATVEMKGDFGKGTLLIHTDRINGNPCLYSDTEGAALAAKGLNQHSNSQVCTVNKEGQRKPENICVSSKETTSVSELSNTECVSEESKTCKEVLLKDSRHSVGITSEEKKSSNKGPHRSEPMLIVSAQLECGACGTDGLESRTEIHKTSESGHLENNFSSEPALSEFTRLERTPEPDSKPLHPVLKALPSHSLEVKLFAKEQRTEECEEFTLMSGVIKRSSSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEEERVVELTKLTKSVSAPQISSPEEPVEEVDISKHTEATSGDSGGYLKSCRERENGDGQLMTDFSVCQLTTESEQLEPRGPSKPSAEDSNGNIELQREEAKEDFSETYCSLECTKPSACNPLRDNDSEGQSLESNDGCSLKTPRANNYLDKSIDEFDKYITDPKDTSKLDSLKIEQDLYISVRKTGEDSFSQSIKLVPHICNPVSDPSETSTEFGSVQRECNNFLADDSLLVYTEMQGLQEIELNDSPAPADPAAESCQDKYPQELDNQEQKLVANGTGFHSVTMDGVALESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQAAFPITRQPLGSFGVVSSHSNDVDEDANERMLNFYQAKEKFKKEMKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPSGKLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNVIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPLIGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1352, "header": "tr|A0A8V0Y1A7-1|A0A1D5NX74_CHICK Computationally mapped isoform of Family with sequence similarity 135 member B OS=Gallus gallus OX=9031 GN=FAM135B PE=3 SV=1 CANONICAL=A0A1D5NX74-1" }, "locus": { "chromosome": "2", "start_pos": 143308756, "end_pos": 143186578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021089.1", "url": "https://www.ensembl.org/id/ENSGALT00010021089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012090.1", "url": "https://www.ensembl.org/id/ENSGALP00010012090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428384", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428384", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PSQ6-1", "protein_name": "Protein FAM135B", "gene_name": "fam135b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSEVQGTVEFSLELHKFHNVDLFQRGFYQVRAGLRVSPRVPHRITATTPGYTGECSFSNAGVHDGGVFSRIFQILYRNEEVTLEDHINFRLHLLLDGERVEEAVSEVDVQLKLDLHFTDNEQQLADISSVPVISSRTLGLHFHPQQGLHHHLPVMFDYFHLSVISVSIHASLVALHQPLISFARSGKGTWLGKGSPESEAPPSAMSVENLMFGAGYCKPVPTEGSFYVPSENCLQRAYTWHRRICKLLLAAHRALRSYYTTLMKEIPQLQHIQTEDLPLEETLNQLTIELQLQSGHEKVAEQISKDLTQLCAQLSALWTQFLESTVPNPYIRSYLAQEHHTLRVRRFSEAYFFTEHPKESSLTFQEELINRHAQVSTEMRNSDYLLRMPPLPVECLDIDGDWSSLPIIFEDRYVDTPCLDYNVVHEQNQAVLNSQPCFEPTRVKGQTASPAEKTQDTSLPATSPEEPPSEDCTEMPTYMTLTDHQDDDVTEHIKPRPQAETLTDHVEEADIDGCEFITTSSNSRIHSVDEVTCQYENDGNTMSVDTDDVIDNQEKTSCQKEAANESDHTSSQQTNVFNSGQPLLLVPTDLGELPDLTSLGSFEFLPTYNHDDNLETPGDTGSPDNQEPQTVFDNRHIQAPAKDYGGKDTSPGILLKATLPGTDPLVTSPSRNVIHQIRRLSETPPRGVFLGGAKLMNRSSSVISDSGIESEPSSVAWTLEGRGVVAGGRDILQSLARCRTAHQSSLEGLQTESHGSLPSATQASLTSISSLPYEEEEDRQLNTLTKSASAPQISSPDDTEEDRETPNQETRTVCEANQVTGTRCEANPMRQNKESANEVKRNLQMEETTQQDTTNVLVANHIRDEAANEVKQTLQEVTREDGNTTTNQEKRNVCVANQLRKSEVAANEVKQNLQGVFREDGNETSNQEIDIEESSNQDITDLTFVNPEMLLYQQFLMDSGKDATLEELTENSKDFQGNILLKEYLMDESTEICRCEDEYCEHKRKLESNQYHKDADDISVCHIHLNELEVASMENLPEPTTNDKRTHGIAANEKERPADPIEPPTNERDQQILEGQSRINKVPSTGLAFVNKKVVEVVNLSVSCAPTCLPFSSVLRDSPSVSGISTRQATSPITHQPLGSFGIISSNSFFGADQEINERMINFFKAKEALLRELVFRGTLYSDLPYLASEHPYFPPEEDDTEFEDGIHLVVCVHGLDGNSADLRLVKTFVELGLPGSRLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLTIHRISFIGHSLGNVIIRSVLTRPRFRCYLCKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDPRQTFLYTLSKKPGLQFFKNVVLVASPQDRYVPFHSARIEMCRTALKDRTTGPVYTEMINNLLQPLLSAPNCRLIRQNVFHALPNTANTLIGRAAHIAVLDSELFLEKFLLVAGLNYFK", "length": 1475 }, "evidence": [ { "id": "A0A1D5NX74", "url": "https://omabrowser.org/oma/group/A0A1D5NX74/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LZ91-1", "protein_name": "Family with sequence similarity 135, member B", "gene_name": "Fam135b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESSSLHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHYTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTSEGSFYVPSENCIQHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTMELEVLAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFEVPVTSPAIMKLKGKEKSVINQKSSSRKEAPLSTTEAPELGSDEDVIQCPEMEENVSTQNPMDVCSESQVYLSIGEFQNRAGIPEDECWTGPRPDAVKDSLTDVDICRRSPGPEEGHTPALTYIDVESSNKNYPRAEPVLGLNVQHEPRGSRDSYGIVKTMPSKVLAGISQNNSISVNQTAALELRTLGRGVGQEGKPVLLSLKLTPAEPCDPLSTGLREALDTKPSLPDPGEEPEDLSVLSGVIKRSASIISDSGIESEPSSVAWSEARSRALEIPSDRDILHQVVRRHAHHRNSLEGGHTESNTSLPSAIQASLSSISSLPFEDEERELALTKLTKSVSAPQISSPEDTAEDSDTIKNTAGFSEDLDLSSKDNSSSRYSSPSYSGSRVQDVRAGHSLADIAVASDRPQGPGYMDIHKGNENHPDLQGPCCLDAMAENIPHVETKGLNLKIPCTTVLENPKTRSFHRTAVETAKGKAKELSLSKHMLSNNSISEVRAASHHRVPEISCAPAVGAGHLHSTGVQNGSLSVNDTMTLNRRHNASPEAKHEAGTVCPTVTHTIASPVSRNQELKAGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQSPAPITHQPLGSFGVVSTYSSELEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1403 }, "evidence": [ { "id": "A0A1D5NX74", "url": "https://omabrowser.org/oma/group/A0A1D5NX74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RRW0-1", "protein_name": "Family with sequence similarity 135 member B", "gene_name": "FAM135B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSGSLRSACIHESTVHSRVFQILYRNEEVPVNDAVIFRAHLLLDGERVEEALSEVDFQLKVDLHFTDSQQQLRDVAGVPVISSRVLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVALQQPLISFTRPGRGPWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSSEGSFYVPSENCMQHAYKWHRELCFLLLHAYRGLRAYFLTIMRDVPELPHMELESLAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWSTLPVIFEDRYVDCPATGHHLSVYPNFDAPASSPAITNLKDSEENHIGSRDAAVREDPVLPTRKPPPKNSDEELVRCPEPEENVPTPSHVDMCSESQVYLTIGEFQDKPGLPEAEHWPGQRSDVGRHLLADEDLPRSSLGPEDGQAPALTYIDVQSSSKNTCSAEPTVVTGAPHERGCWPSNSELHRAELSQGGGGGSRQNATSSEKTTLRELSPLGKGADPGSKMVLLSLRLVPSEPCDPLNPSLRDPVGLRASPRDAPAEEQEEGPVLSGAIERSSSVISDSGIESEPSSVAWSEARSRALELPGDREVLHQLVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEEERELARTKLTKSVSAPQISSPEESAEDADTTQPGGGLAETPAEDSESRDPSGPCLPLSGGSGSRDAGVAHLLAEVVSDASHQQGPGYIDTPKGKEKVDPQGPCCLDGRTDNPPGVETKGLSLKIPPILALENPKNQPLPGAPVEAPKGRPEDANVGERPLPNSGILDAETFTHHKVPEVSSTSAANTVDLDSTSERGSSPCTAEDTVLRRGARTFPEDGREEGPACSPVSRSLHSQSTGNQEPRAGPSTVMSHLASAETFPLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTAFPITHQPLGSFGVVPTHSGKLEEEVSERMFSFYQAKENFKKELKIDGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSIARISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPLVDAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1404 }, "evidence": [ { "id": "A0A1D5NX74", "url": "https://omabrowser.org/oma/group/A0A1D5NX74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q49AJ0-1", "protein_name": "Protein FAM135B", "gene_name": "FAM135B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESSSLHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQLKVDLHFTDSEQQLRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVALQQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSSEGSFYITSENCMQHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTELEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPATGHNLSVYPNFDVPVTSPTIMNLKDKEDNCMVNSNLSFREDLVLSTIKPSQMDSDEEVIRCPEPGENVATQNHMDMCSESQVYISIGEFQNKAGVPEDECWTGQTSDAGTYPVADVDTSRRSPGPEDGQAPVLTYIDVKSSNKNPSRAEPLVAFNAQHESRSSRDKYGLDRTGLSKVVVGGSHQNAISSDKTTLHELSTLGKGIDQEGKMVLLSLKLTPSEPCDPLSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRSSSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEDEREVALTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEPSDMHSKSQGSPGSCSQLCGDSGTDAGADHPLVEIVLDADNQQGPGYIDIPKGKGKQFDAQGHCLPDGRTENTPGVETKGLNLKIPRVIALENPRTRSLHRALEETPKGMPKDLNVGQQALSNSGISEVEGLSQHQVPELSCTSAADAINRNSTGQQSQSGSPCIMDDTAFNRGVNAFPEAKHKAGTVCPTVTHSVHSQVLKNQELKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTLFPITHQPLGSFGVVSTHSSTLDEEVSERMFSFYQAKEKFKKELKIEGFLYSDLTVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1406 }, "evidence": [ { "id": "A0A1D5NX74", "url": "https://omabrowser.org/oma/group/A0A1D5NX74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAI6-1", "protein_name": "Protein FAM135B", "gene_name": "Fam135b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESSSLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHFTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMELEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKEKNLINQNSSSRKDIPLSTTEAPQLGSDEDVTRRPEVQENVSTWNPIDVCSESQVYLTIGEFQNRAGIPEDECWTGPRPDAVKDSLTDTDICSRSPGPDEGQTPALTYIDVQSSNKYCPRAELVQGINVQHEHRSSRESYGIVKTVPSKVVAGTSQNNSTSLNQTAALELRTLGRGVNQDGKPVLLSLKLTPAEPCDPPSTALREALDTKPSQPDHAEEPEDLSALSGVIKRSASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSGIQASLSSISSLPFEEEERELALNKLTKSVSAPQISSPEESAEGADTIKNTAGFSEDLDPSSKENSPPRHTSLSYGGSRVQDVRAGHSLADIALDSDRPQGPGYMDIPNDKGNHPELQEPCCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAKGKPEELSMSKCVLSNNSISEVRAASHHRVPEISCSPAVEAVNLNSTGVQNSSLSVNDTMTLNRRHNASLEAKHEAGTVCPTVTHTIASQVSRNQELKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSKLEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1403 }, "evidence": [ { "id": "A0A1D5NX74", "url": "https://omabrowser.org/oma/group/A0A1D5NX74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX74", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, 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"sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1046, "end_pos": 1048 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1270, "end_pos": 1272 }, { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 871, "end_pos": 873 }, { "start_pos": 991, "end_pos": 993 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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"start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1271 }, { "field": "total_sites", "count": 848 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1266 }, { "field": "total_sites", "count": 845 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NX84-1", "uniprot_ac": "A0A1D5NX84", "uniprot_id": "A0A1D5NX84_CHICK", "mass": { "chemical_mass": 42998.0, "monoisotopic_mass": 42998.0 }, "refseq": { "ac": "XP_046763094", "name": "traB domain-containing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094" }, "gene_names": [ { "name": "TRABD", "type": "recommended", "evidence": [ { "id": "A0A1D5NX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ] }, { "name": "TRABD", "type": "synonym", "evidence": [ { "id": "XP_046763094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094" } ] } ], "protein_names": [ { "name": "TraB domain containing", "type": "synonym", "evidence": [ { "id": "A0A1D5NX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84/entry#names_and_taxonomy" } ] }, { "name": "traB domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046763094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046763094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRABD", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84", "locus": { "chromosome": "1", "start_pos": 20442353, "end_pos": 20410056, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001540", "url": "https://www.ensembl.org/id/ENSGALG00010001540" } ] } } ], "crossref": [ { "id": "A0A1D5NX84", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NX84", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030705", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030705", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417746", "url": "https://www.ncbi.nlm.nih.gov/gene/417746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "INEIMVA", "url": "https://omabrowser.org/oma/group/INEIMVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NX84", "url": "https://www.orthodb.org/?gene=A0A1D5NX84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X5Y7", "url": "https://www.orthodb.org/?gene=A0A8V0X5Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21530:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21530:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046763094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NX84-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDAARCPTNAPGAGAPRCRFPSPAAPRPAAVPPPLGGPHRAREREADADAFKILLEMKMKKRQKKPALPSTVTELNTEDGSKVYVVGTAHFSDSSKKDVVKTIQEVQPDVVVVELCQYRVSMLKMDEKTLLKEAKEINLEKLQQAIKQNGVMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVEKCKQKDLLEQMMAEMIGEFPDLHRTIVSERDIYLTYMLKQAAKQIELPRASETEPQRYIPAVVVGVVGMGHVPGIEKNWNSDLNIQEIMSVPPPSASSKIFKFVIKATVFGLMGYGCYRIGQRTVQFILSMPAAQSYLQKLTEIRSQH", "length": 386, "header": "tr|A0A1D5NX84-1|A0A1D5NX84_CHICK Isoform 1 of TraB domain containing OS=Gallus gallus OX=9031 GN=TRABD PE=1 SV=1 CANONICAL=A0A1D5NX84-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NX84-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84/entry", "sequence": { "sequence": "MTDAARCPTNAPGAGAPRCRFPSPAAPRPAAVPPPLGGPHRAREREADADAFKILLEMKMKKRQKKPALPSTVTELNTEDGSKVYVVGTAHFSDSSKKDVVKTIQEVQPDVVVVELCQYRVSMLKMDEKTLLKEAKEINLEKLQQAIKQNGVMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVEKCKQKDLLEQMMAEMIGEFPDLHRTIVSERDIYLTYMLKQAAKQIELPRASETEPQRYIPAVVVGVVGMGHVPGIEKNWNSDLNIQEIMSVPPPSASSKIFKFVIKATVFGLMGYGCYRIGQRTVQFILSMPAAQSYLQKLTEIRSQH", "length": 386, "header": "tr|A0A1D5NX84-1|A0A1D5NX84_CHICK Isoform 1 of TraB domain containing OS=Gallus gallus OX=9031 GN=TRABD PE=1 SV=1 CANONICAL=A0A1D5NX84-1" }, "locus": { "chromosome": "1", "start_pos": 20439360, "end_pos": 20410090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003546.1", "url": "https://www.ensembl.org/id/ENSGALT00010003546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001984.1", "url": "https://www.ensembl.org/id/ENSGALP00010001984.1" } ] } }, { "isoform_ac": "A0A8V0X5Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Y7/entry", "sequence": { "sequence": "MQEEQQPEAAADPMSSSDVPEDGPKETSSVSQTDADAFKILLEMKMKKRQKKPALPSTVTELNTEDGSKVYVVGTAHFSDSSKKDVVKTIQEVQPDVVVVELCQYRVSMLKMDEKTLLKEAKEINLEKLQQAIKQNGVMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVEKCKQKDLLEQMMAEMIGEFPDLHRTIVSERDIYLTYMLKQAAKQIELPRASETEPQRYIPAVVVGVVGMGHVPGIEKNWNSDLNIQEIMSVPPPSASSKIFKFVIKATVFGLMGYGCYRIGQRTVQFILSMPAAQSYLQKLTEIRSQH", "length": 372, "header": "tr|A0A8V0X5Y7-1|A0A1D5NX84_CHICK Computationally mapped isoform of TraB domain containing OS=Gallus gallus OX=9031 GN=TRABD PE=1 SV=1 CANONICAL=A0A1D5NX84-1" }, "locus": { "chromosome": "1", "start_pos": 20439360, "end_pos": 20420202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003548.1", "url": "https://www.ensembl.org/id/ENSGALT00010003548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001986.1", "url": "https://www.ensembl.org/id/ENSGALP00010001986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to mitochondrion", "id": "GO:0070585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070585", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mitochondrion-mitochondrion outer membrane tether activity", "id": "GO:0160204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160204", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TOM complex", "id": "GO:0140596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140596", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NX84", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NX84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NX84-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 386, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NX84-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NX84" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NXK4-1", "uniprot_ac": "A0A1D5NXK4", "uniprot_id": "A0A1D5NXK4_CHICK", "mass": { "chemical_mass": 61973.0, "monoisotopic_mass": 61973.0 }, "refseq": { "ac": "XP_001233732", "name": "protein FAM124A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732" }, "gene_names": [ { "name": "FAM124A", "type": "recommended", "evidence": [ { "id": "A0A1D5NXK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4" } ] }, { "name": "FAM124A", "type": "synonym", "evidence": [ { "id": "XP_001233732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 124 member A", "type": "synonym", "evidence": [ { "id": "A0A1D5NXK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4/entry#names_and_taxonomy" } ] }, { "name": "protein FAM124A", "type": "synonym", "evidence": [ { "id": "XP_001233732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001233732.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXK4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM124A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4", "locus": {} } ], "crossref": [ { "id": "A0A1D5NXK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017016", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017016", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770395", "url": "https://www.ncbi.nlm.nih.gov/gene/770395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770395", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770395", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVRWQTE", "url": "https://omabrowser.org/oma/group/DVRWQTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXK4", "url": "https://www.orthodb.org/?gene=A0A1D5NXK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7L1", "url": "https://www.orthodb.org/?gene=A0A8V0X7L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233732", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXK4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7L1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQQQQQQPRGGEEDCGDSGAETGGSEYSRMSSTSSELSVEDIQDPFLVSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVSERRVSKKHRKPDKAGVSQPALAVILFLQEEYGEEPILQLHETFQRPPWHYHHTERVHGKFLPYMPCSQDFYTLAPETPLWAIRPVHYGKEIIRFTIYCRNENFVDILKFYELILKRPVCQKKADFCVFPIYSNMEIDIQFSLKKLPKGHVPMPTESAVLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQQARSWCRKSAKQNKQPYPSVSTDSHFTTLPGFHPQSHQSVPEQPKEMSQNKVHHANGLGHYLGFSQQDLRHSDQEDFTRRSSSASSILWSFQRSKSLFCLPTVSSSSASETAHFSEAFQFLNTESPATRLKTWRCSPRLNIDDLEDAQETDVDTGRKLSFSDLSVVSAYSALNRFCNDLEASLPPQKQTCSTSTKASTSGRPVSTMCGTFDPMDGSLPSLSEWSSSSFMSASLSKQPKQSSRTASCSLDDCGSIFPASPTNDEEFYI", "length": 549, "header": "tr|A0A1D5NXK4-1|A0A1D5NXK4_CHICK Isoform 1 of Family with sequence similarity 124 member A OS=Gallus gallus OX=9031 GN=FAM124A PE=3 SV=2 CANONICAL=A0A1D5NXK4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXK4/entry", "sequence": { "sequence": "MQQQQQQQPRGGEEDCGDSGAETGGSEYSRMSSTSSELSVEDIQDPFLVSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVSERRVSKKHRKPDKAGVSQPALAVILFLQEEYGEEPILQLHETFQRPPWHYHHTERVHGKFLPYMPCSQDFYTLAPETPLWAIRPVHYGKEIIRFTIYCRNENFVDILKFYELILKRPVCQKKADFCVFPIYSNMEIDIQFSLKKLPKGHVPMPTESAVLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQQARSWCRKSAKQNKQPYPSVSTDSHFTTLPGFHPQSHQSVPEQPKEMSQNKVHHANGLGHYLGFSQQDLRHSDQEDFTRRSSSASSILWSFQRSKSLFCLPTVSSSSASETAHFSEAFQFLNTESPATRLKTWRCSPRLNIDDLEDAQETDVDTGRKLSFSDLSVVSAYSALNRFCNDLEASLPPQKQTCSTSTKASTSGRPVSTMCGTFDPMDGSLPSLSEWSSSSFMSASLSKQPKQSSRTASCSLDDCGSIFPASPTNDEEFYI", "length": 549, "header": "tr|A0A1D5NXK4-1|A0A1D5NXK4_CHICK Isoform 1 of Family with sequence similarity 124 member A OS=Gallus gallus OX=9031 GN=FAM124A PE=3 SV=2 CANONICAL=A0A1D5NXK4-1" }, "locus": { "chromosome": "1", "start_pos": 169935695, "end_pos": 169898530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006687.1", "url": "https://www.ensembl.org/id/ENSGALT00010006687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004093.1", "url": "https://www.ensembl.org/id/ENSGALP00010004093.1" } ] } }, { "isoform_ac": "A0A8V0X7L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7L1/entry", "sequence": { "sequence": "MDSTTADRRASQGELSVEDIQDPFLVSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVSERRVSKKHRKPDKAGVSQPALAVILFLQEEYGEEPILQLHETFQRPPWHYHHTERVHGKFLPYMPCSQDFYTLAPETPLWAIRPVHYGKEIIRFTIYCRNENFVDILKFYELILKRPVCQKKADFCVFPIYSNMEIDIQFSLKKLPKGHVPMPTESAVLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQQARSWCRKSAKQNKQPYPSVSTDSHFTTLPGFHPQSHQSVPEQPKEMSQNKVHHANGLGHYLGFSQQDLRHSDQEDFTRRSSSASSILWSFQRSKSLFCLPTVSSSSASETAHFSEAFQFLNTESPATRLKTWRCSPRLNIDDLEDAQETDVDTGRKLSFSDLSVVSAYSALNRFCNDLEASLPPQKQTCSTSTKASTSGRPVSTMCGTFDPMDGSLPSLSEWSSSSFMSASLSKQPKQSSRTASCSLDDCGSIFPASPTNDEEFYI", "length": 526, "header": "tr|A0A8V0X7L1-1|A0A1D5NXK4_CHICK Computationally mapped isoform of Family with sequence similarity 124 member A OS=Gallus gallus OX=9031 GN=FAM124A PE=3 SV=1 CANONICAL=A0A1D5NXK4-1" }, "locus": { "chromosome": "1", "start_pos": 169935695, "end_pos": 169921089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006686.1", "url": "https://www.ensembl.org/id/ENSGALT00010006686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004092.1", "url": "https://www.ensembl.org/id/ENSGALP00010004092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770395", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV50-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "Fam124a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPKAAGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTSRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYADSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRAHKKGPKCSRAHHSSEKKPHSAPPAAIDTPNTGQGSSQTALRDSPSKQMAPLPGNKQEYSPQLNTSSPAWSFQRSKSLFCLPSGGTSTTEPQPLLTGSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCNTVEASLSSEGCSSRWPAHKSPEKGPLPAASEVSPDTACVSHPLFTKGSPSPAEITTPGLSASGASLLTESSTPPPCHDPKATQGVQDIVLPPTTVGPEADDMEEFYI", "length": 536 }, "evidence": [ { "id": "A0A1D5NXK4", "url": "https://omabrowser.org/oma/group/A0A1D5NXK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z5V4-1", "protein_name": "Family with sequence similarity 124, member A", "gene_name": "Fam124a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPKAGGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTTRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYTDSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRTHKKAPKYSRAHHSSEKKPHSAPPAAVDTPNTGQGSSQTALHDSPSNQIARLPGDKQEYNTQSSTSSPAWSFPRSKSLFCLPSGGPSPTEPQPLPTNSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFYNTIEAPLSSERCSSHWPAHKSPKKGPMPAASEVSPDTACVSHPLFTKGSPRPAETTTPALSASDASLLTESSTHTPCHDPKATQGVQGMLLPPTTVGPETDDMEEFYI", "length": 536 }, "evidence": [ { "id": "A0A1D5NXK4", "url": "https://omabrowser.org/oma/group/A0A1D5NXK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1Q587-1", "protein_name": "Protein FAM124A isoform X1", "gene_name": "fam124a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENSVEDECADSGAETGGSDYSLMSSASSDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 559 }, "evidence": [ { "id": "A0A1D5NXK4", "url": "https://omabrowser.org/oma/group/A0A1D5NXK4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3N0A0-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "FAM124A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPKAGGGEEDDCVDSGAETGGSDYSHVSSTSSEYSTEEVQDPFLVSIHIIADPGESRPLQEAIDKVLAWIHPDLPLFRVSERRACRRRRRVPKAAQPALAVVLFLQEEYGEEPILQLHRTLQRPPWRHHHTERVPGKFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHDNYADILKFYELILKRSPSQKKADFCIFPIFSNLDMDIQFSLKRLPCDQTPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQKGHRKRPKPGRAHQASEQKPCSTSSPRATAQSRTPGCCSQPPLDASHPGLSQAGPSTRHPQEFARRATSPPSLPWSFQRSKSLFCLPTGDPSPASAAEAQLSASIGGRGQRAPERGHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSPEEAPHPPERGSGLWSERRGFREGPLPTAGGETAGASWATLPVFKGPSGSSATAVTAPPALDTSSLTETPPELPSDAPQAQQTGRDVLAPSVPAGCGDNDTEEFYI", "length": 544 }, "evidence": [ { "id": "A0A1D5NXK4", "url": "https://omabrowser.org/oma/group/A0A1D5NXK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86V42-1", "protein_name": "Protein FAM124A", "gene_name": "FAM124A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI", "length": 546 }, "evidence": [ { "id": "A0A1D5NXK4", "url": "https://omabrowser.org/oma/group/A0A1D5NXK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NXK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 549, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NXK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NXN4-1", "uniprot_ac": "A0A1D5NXN4", "uniprot_id": "A0A1D5NXN4_CHICK", "mass": { "chemical_mass": 18041.0, "monoisotopic_mass": 18041.0 }, "refseq": { "ac": "XP_418851", "name": "protein phosphatase 1 regulatory subunit 17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418851" }, "gene_names": [ { "name": "PPP1R17", "type": "recommended", "evidence": [ { "id": "A0A1D5NXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4" } ] }, { "name": "PPP1R17", "type": "synonym", "evidence": [ { "id": "XP_418851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418851" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 17", "type": "synonym", "evidence": [ { "id": "A0A1D5NXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 17", "type": "synonym", "evidence": [ { "id": "XP_418851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418851.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R17", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4", "locus": { "chromosome": "2", "start_pos": 48403511, "end_pos": 48423208, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019657", "url": "https://www.ensembl.org/id/ENSGALG00010019657" } ] } } ], "crossref": [ { "id": "A0A1D5NXN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036390", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036390", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420753", "url": "https://www.ncbi.nlm.nih.gov/gene/420753", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420753", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420753", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDPRCGH", "url": "https://omabrowser.org/oma/group/LDPRCGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXN4", "url": "https://www.orthodb.org/?gene=A0A1D5NXN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA86", "url": "https://www.orthodb.org/?gene=A0A8V0ZA86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB13", "url": "https://www.orthodb.org/?gene=A0A8V0ZB13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15387:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15387:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSTECVQPLDIPEDRLDKRDSHCNHLEDLSEQLIKSCDLKKKPRKGKTIQPSQNAEQEQKKPRRKDTPAIHTPPPLTGILSDFSDNLLKRYGISEKPQRERVSQGSQITELEQKKPRRKDTPAIHIPPLIIGTKLLTEEKQTAIMEDEEKDGDTIPS", "length": 158, "header": "tr|A0A1D5NXN4-1|A0A1D5NXN4_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 17 OS=Gallus gallus OX=9031 GN=PPP1R17 PE=4 SV=1 CANONICAL=A0A1D5NXN4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4/entry", "sequence": { "sequence": "MMSTECVQPLDIPEDRLDKRDSHCNHLEDLSEQLIKSCDLKKKPRKGKTIQPSQNAEQEQKKPRRKDTPAIHTPPPLTGILSDFSDNLLKRYGISEKPQRERVSQGSQITELEQKKPRRKDTPAIHIPPLIIGTKLLTEEKQTAIMEDEEKDGDTIPS", "length": 158, "header": "tr|A0A1D5NXN4-1|A0A1D5NXN4_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 17 OS=Gallus gallus OX=9031 GN=PPP1R17 PE=4 SV=1 CANONICAL=A0A1D5NXN4-1" }, "locus": { "chromosome": "2", "start_pos": 48416390, "end_pos": 48406331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047426.1", "url": "https://www.ensembl.org/id/ENSGALT00010047426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028097.1", "url": "https://www.ensembl.org/id/ENSGALP00010028097.1" } ] } }, { "isoform_ac": "A0A8V0ZA86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA86/entry", "sequence": { "sequence": "QCSHNPARDIGSPDSPNAESQSVCHSSVKCVQPLDIPEDRLDKRDSHCNHLEDLSEQLIKSCDLKKKPRKGKTIQPSQNAEQEQKKPRRKDTPAIHTPPPLTGILSDFSDNLLKRYGISEKPQRERVSQGSQITELEQKKPRRKDTPAIHIPPLIIGTKLLTEEKQTAIMEDEEKDGDTIPS", "length": 182, "header": "tr|A0A8V0ZA86-1|A0A8V0ZA86_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 17 OS=Gallus gallus OX=9031 GN=PPP1R17 PE=4 SV=1 CANONICAL=A0A1D5NXN4-1" }, "locus": { "chromosome": "2", "start_pos": 48422969, "end_pos": 48406331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047430.1", "url": "https://www.ensembl.org/id/ENSGALT00010047430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028100.1", "url": "https://www.ensembl.org/id/ENSGALP00010028100.1" } ] } }, { "isoform_ac": "A0A8V0ZB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB13/entry", "sequence": { "sequence": "MMSTECVQPLDIPEDRLDKRDSHCNHLEDLSEQLIKSCDLKKKPRKGKTIQPSQNAEQEQKKPRRKDTPAIHTPPPLTGILSDFSDNLLKRYGISEKPQRERVSQGSQITELEQKKPRRKDTPAIHIPPLIIGTKLLTEEKQTAIMEDEEKDGDTIPRGSYKM", "length": 163, "header": "tr|A0A8V0ZB13-1|A0A8V0ZB13_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 17 OS=Gallus gallus OX=9031 GN=PPP1R17 PE=4 SV=1 CANONICAL=A0A1D5NXN4-1" }, "locus": { "chromosome": "2", "start_pos": 48416390, "end_pos": 48404040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047434.1", "url": "https://www.ensembl.org/id/ENSGALT00010047434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028102.1", "url": "https://www.ensembl.org/id/ENSGALP00010028102.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420753", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420753", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H6Z4-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "Ppp1r17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATEMMATEPVQPLELSEDILDKFDPHCDSSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESEQKKPRRKDTPALHIPPFIPGVISEHLIKRYDVQDRVPKVKTGSGLHNTDMEQKRPRRKDTPALHMPPFVAGLTLLGDESPRVIMEDDEKDGDKITI", "length": 159 }, "evidence": [ { "id": "A0A1D5NXN4", "url": "https://omabrowser.org/oma/group/A0A1D5NXN4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1N1Q9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "PPP1R17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSTEQMQPLELSEDRLDKLDPRCSHLDDLSDQFIKDCDLKKKPIKGKNVQVTLNVESDQKKPRRKDTPALHVPPFIPDVLSEHLITRYDVQDIQPKGKMSPVLHNTDLEQKKPRRKDTPALHVSPFAAGVTLLRDERPKVIVEDDEKDGDKIAI", "length": 155 }, "evidence": [ { "id": "A0A1D5NXN4", "url": "https://omabrowser.org/oma/group/A0A1D5NXN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O96001-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "PPP1R17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSTEQMQPLELSEDRLDKLDPRCSHLDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPALHIPPFIPGVFSEHLIKRYDVQERHPKGKMIPVLHNTDLEQKKPRRKDTPALHMSPFAAGVTLLRDERPKAIVEDDEKDGDKIAI", "length": 155 }, "evidence": [ { "id": "A0A1D5NXN4", "url": "https://omabrowser.org/oma/group/A0A1D5NXN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2E4-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "Ppp1r17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTEMMTTEPVPPLELSDDILGKLDPQCSPSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPAVHIPPFIPGVISEHLIKRYDVQERIPKAKSGPALHNSDMEQKRPRRKDTPALHMPPFVAGLTLLRDESAGVILEDEEMDGDKLAI", "length": 159 }, "evidence": [ { "id": "A0A1D5NXN4", "url": "https://omabrowser.org/oma/group/A0A1D5NXN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146069" }, "gene_names": [ { "name": "IVNS1ABP", "type": "recommended", "evidence": [ { "id": "A0A1D5NXS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8" } ] }, { "name": "IVNS1ABP", "type": "synonym", "evidence": [ { "id": "XP_015146069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146069" } ] } ], "protein_names": [ { "name": "Influenza virus NS1A binding protein", "type": "synonym", "evidence": [ { "id": "A0A1D5NXS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8/entry#names_and_taxonomy" } ] }, { "name": "influenza virus NS1A-binding protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015146069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IVNS1ABP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8", "locus": { "chromosome": "8", "start_pos": 10644046, "end_pos": 10626560, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021168", "url": "https://www.ensembl.org/id/ENSGALG00010021168" } ] } } ], "crossref": [ { "id": "A0A1D5NXS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXS8", "database": 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}, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146069", "url": 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"MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDSHGISHVKFDDLNPDAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMERVKQVCGDYLLSKMDVQSCISYRNFVSCMGDSRLLSKIDGYIQEHLLQISEQEEFLKLPRLKLEVMLEDNVGLPSNGKLYTKVINWVQRSIWENGDSLEDLMEEVQTLYYSADHKLLDGNLLDGQAEVYGSDDDHIQFVQKKPPRENDHKQISSSSSGSLSPSAAVQSPKHEWKIIASEKTSSNTYLCLAVLDSVLCVIFLHGRNSPQSSPTSTPRLLKSLSFELQPNDVIEKPMSPMQYARSGLGTAELNGKLIAAGGYNREECLRTVECYDPQRDIWTFIAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYEPEIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPITKSWTSCAPLNIRRHQSAVCELGGHLYIIGGAESWNCLSSVERYNPENNTWTLMAPMNVARRGAGVAVHDGKLFVGGGFDGSHAVSCMEMYDPAKNEWKMMGNMTTPRSNAGITTVANTIYAVGGFDGNEFLNTVEVYNSESNEWSPYTKIYKF", "length": 641, "header": "tr|A0A1D5NXS8-1|A0A1D5NXS8_CHICK Isoform 1 of Influenza virus NS1A binding protein OS=Gallus gallus OX=9031 GN=IVNS1ABP PE=4 SV=2 CANONICAL=A0A1D5NXS8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8/entry", "sequence": { "sequence": 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"url": "https://www.ensembl.org/id/ENSGALT00010051276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030467.1", "url": "https://www.ensembl.org/id/ENSGALP00010030467.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ7/entry", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDSHGISHVKFDDLNPDAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMERVKQVCGDYLLSKMDVQSCISYRNFVSCMGDSRLLSKIDGYIQEHLLQISEQEEFLKLPRLKLEVMLEDNVGLPSNGKLYTKVINWVQRSIWENGDSLEDLMEEVY", "length": 221, "header": "tr|A0A8V0ZGQ7-1|A0A8V0ZGQ7_CHICK Computationally mapped isoform of Influenza virus NS1A binding protein OS=Gallus gallus OX=9031 GN=IVNS1ABP PE=4 SV=1 CANONICAL=A0A1D5NXS8-1" }, "locus": { "chromosome": "8", "start_pos": 10636302, "end_pos": 10633231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051272.1", "url": "https://www.ensembl.org/id/ENSGALT00010051272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030463.1", "url": "https://www.ensembl.org/id/ENSGALP00010030463.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426862", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXS8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NXS8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 641, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NXS8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NXS8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 535, "end_pos": 537 }, { "start_pos": 590, 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NY06-1", "uniprot_ac": "A0A1D5NY06", "uniprot_id": "A0A1D5NY06_CHICK", "mass": { "chemical_mass": 33509.0, "monoisotopic_mass": 33509.0 }, "refseq": { "ac": "XP_015152659", "name": "spermidine synthase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659" }, "gene_names": [ { "name": "SRM", "type": "recommended", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ] }, { "name": "SRM", "type": "synonym", "evidence": [ { "id": "XP_015152659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659" } ] } ], "protein_names": [ { "name": "Spermidine synthase", "type": "recommended", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.16", "type": "synonym", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06/entry#names_and_taxonomy" } ] }, { "name": "Putrescine aminopropyltransferase", "type": "synonym", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06/entry#names_and_taxonomy" } ] }, { "name": "spermidine synthase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659" } ] }, { "annotation": "Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06#function" }, { "database": "UniProtKB", "id": "ARBA00053963", "url": "https://www.uniprot.org/uniprotkb/ARBA00053963#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRM", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06", "locus": { "chromosome": "21", "start_pos": 4107690, "end_pos": 4112963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021731", "url": "https://www.ensembl.org/id/ENSGALG00010021731" } ] } } ], "crossref": [ { "id": "A0A1D5NY06", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NY06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003039", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003039", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771447", "url": "https://www.ncbi.nlm.nih.gov/gene/771447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLYHEMM", "url": "https://omabrowser.org/oma/group/FLYHEMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NY06", "url": "https://www.orthodb.org/?gene=A0A1D5NY06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11558:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11558:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-351202", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12721", "url": "https://www.rhea-db.org/rhea/12721", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NY06-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERGAAALIREGWFRETCRLWPGQAMSLQVEELLHHQRSRYQEILVFRSTTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPDPRKVLIIGGGDGGVLREVVKHPTVESVVQCEIDEDVIQVSKKYLPGMAVGYSSAKLTLHVGDGFEFMKQNQEAFDVIITDSSDPMGPAESLFKESYYQLMKTALREDGILCCQGECQWLHLDLIKEMRQFCKSLFPVVEYAYCTIPTYPSGQIGFMLCSKNPNTNFREPVQQLSQQQVEERSLKYYNSDIHRAAFILPEFARKALSDV", "length": 294, "header": "tr|A0A1D5NY06-1|A0A1D5NY06_CHICK Isoform 1 of Spermidine synthase OS=Gallus gallus OX=9031 GN=SRM PE=1 SV=2 CANONICAL=A0A1D5NY06-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NY06-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06/entry", "sequence": { "sequence": "MERGAAALIREGWFRETCRLWPGQAMSLQVEELLHHQRSRYQEILVFRSTTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPDPRKVLIIGGGDGGVLREVVKHPTVESVVQCEIDEDVIQVSKKYLPGMAVGYSSAKLTLHVGDGFEFMKQNQEAFDVIITDSSDPMGPAESLFKESYYQLMKTALREDGILCCQGECQWLHLDLIKEMRQFCKSLFPVVEYAYCTIPTYPSGQIGFMLCSKNPNTNFREPVQQLSQQQVEERSLKYYNSDIHRAAFILPEFARKALSDV", "length": 294, "header": "tr|A0A1D5NY06-1|A0A1D5NY06_CHICK Isoform 1 of Spermidine synthase OS=Gallus gallus OX=9031 GN=SRM PE=1 SV=2 CANONICAL=A0A1D5NY06-1" }, "locus": { "chromosome": "21", "start_pos": 4112923, "end_pos": 4108312, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052809.1", "url": "https://www.ensembl.org/id/ENSGALT00010052809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031715.1", "url": "https://www.ensembl.org/id/ENSGALP00010031715.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771447", "resource": "KEGG Pathway" }, { "id": "R-GGA-351202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351202", "resource": "Reactome", "description": "Metabolism of polyamines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480SJI2-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFHETCSLWPGQALSLQVEQLLHHQRSRYQDILVFRSKSYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPAVESVVQCEIDEDVIQVSKKFLPGMAVSYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEEGILCCQGECQWLHLDLIKEMRQFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPVQLLTQKQVEQRQLRYYNSDVHRAAFVLPEFARKALNDAD", "length": 302 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BM12-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHQRSRYQDILVFRSKSYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHSSVEAVVQCEIDEDVIQVSKKFLPSMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCTIPTYPSGQIGFMLCSKNPSTNFREPLQPLMQKQVEEMQLKYYNSDVHRAAFVLPEFARKALNDVS", "length": 302 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1R3G8-1", "protein_name": "Spermidine synthase", "gene_name": "srm", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNIKDGWFTETCTLWPGQAMSLQVEEVLYHKKSKFQDVMVFKSKTYGNVLILDGVIQCTERDEFSYQEMIANLPLCCHPCPKKVLIIGGGDGGVLREVVKHPLVESVVQCEIDEDVINVSKKYLPGMAKGFFSPKLTLHVGDGFEFMKKNQDAFDIIITDSSDPVGPAESLFKESYYQLMKTALCEGGILCCQGECQWLHLELIKEMRTFCKTLFPVVDYAYCTIPTYPSGQIGFMLCSKNSKTNFREPLRELTRDEIESMSLKYYNPEIHRAAFILPEFARKVLSEA", "length": 289 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P19623-1", "protein_name": "Spermidine synthase", "gene_name": "SRM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDVS", "length": 302 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12074-1", "protein_name": "Spermidine synthase SPE3", "gene_name": "SPE3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAQEITHPTIVDGWFREISDTMWPGQAMTLKVEKVLHHEKSKYQDVLIFKSTTYGNVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIRLSKEYLPEMAASYSHPKVKTHIGDGFQFLRDYQNTFDVIITDSSDPEGPAETLFQKEYFQLLNSALTEKGVITTQAESMWIHLPIIKDLKKACSEVFPVAEYSFVTIPTYPTGTIGFMVCSKDKTCNVKKPLREISDEKEAELYRYYNKKIHEASFVLPTWAAKELN", "length": 293 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q64674-1", "protein_name": "Spermidine synthase", "gene_name": "Srm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMAVGFSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCSIPTYPSGQIGFMLCSKNPSTNFREPVQQLTQAQVEQMQLKYYNSDMHRAAFVLPEFTRKALNDIS", "length": 302 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJS8-1", "protein_name": "Mannan-binding lectin serine protease 2", "gene_name": "Masp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF", "length": 685 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VHA1-1", "protein_name": "Spermidine synthase, isoform A", "gene_name": "SpdS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSLNNGWFSELQADLWPGQSFSLKVKEVIHKEKSRFQDIQIVETETYGRCLILDGIIQCTARDEFSYQEMISFLPLCAHPNPKKVLIVGGGDGGVAREVVKHPLVEEVHQVEIDDRVVELSKQYLPAMACGFANEKLKLTIGDGFDYMKKHKNEFDVIITDSSDPIGPAVSLFQESYYELMKHALKDDGIVCSQGGSFWLDLDYIKKTMSGCKEHFAKVAYAVTSVPSYPCGHIGFVMGSLNKNQDFATPKLGKSEIDSIDLRYYSSEVHSAAFALPRWVQKHFYE", "length": 287 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9XY92-1", "protein_name": "Spermidine synthase", "gene_name": "spsA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDKIQNGWFSEISEFWPGNSFSLEVEKVLHHEKSEYQDFLVFKSKSFGNVLVLDGVIQATERDEFAYQEMITHIPLFSHPSPKRVLVVGGGDGGVLREVVKHPLVESVTLCEIDKGVIEASRNFLPNMRVGFDHPKVTLFIGDGMEFMRQRKGEFDVIITDSSDPIGPAQGLFERAYYELLKAALAPGGIVCSQCESMWLHLDTIKGLTTFCKELYPNVEYAYTSIPSYPGGSIGFILCSLGGSTKAPIREITPEVQSQMQYYNGEVHKASFVLPQFAAKKLNL", "length": 284 }, "evidence": [ { "id": "A0A1D5NY06", "url": "https://omabrowser.org/oma/group/A0A1D5NY06/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "pmid": "" }, { "name": "spermidine synthase activity", "id": "GO:0004766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004766", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermine biosynthetic process", "id": "GO:0006597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006597", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "pmid": "" }, { "name": "spermidine biosynthetic process", "id": "GO:0008295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008295", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12721", "name": "", "equation": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NY06-1" ], "evidence": [ { "id": "12721", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12721" } ] }, { "id": "R-GGA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5NY06-1" ], "evidence": [ { "id": "R-GGA-351215", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351215" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NY06", "gene_name": "SRM", "activity": [ { "ec_number": "2.5.1.16", "activity": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+).", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ] }, { "ec_number": "2.5.1.16", "activity": "", "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NY06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NY06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NY06" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY06" }, { "id": "PS51006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PABS", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 246, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.16", "ec_name": "S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+).", "evidence": [ { "id": "2.5.1.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.16" }, { "id": "2.5.1.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.16" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NY14-1", "uniprot_ac": "A0A1D5NY14", "uniprot_id": "A0A1D5NY14_CHICK", "mass": { "chemical_mass": 67064.0, "monoisotopic_mass": 67064.0 }, "refseq": {}, "gene_names": [ { "name": "DENND6A", "type": "recommended", "evidence": [ { "id": "A0A1D5NY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14" } ] } ], "protein_names": [ { "name": "DENN domain containing 6A", "type": "synonym", "evidence": [ { "id": "A0A1D5NY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND6A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14", "locus": { "chromosome": "12", "start_pos": 8915601, "end_pos": 8938839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027083", "url": "https://www.ensembl.org/id/ENSGALG00010027083" } ] } } ], "crossref": [ { "id": "A0A1D5NY14", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NY14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005656", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416006", "url": "https://www.ncbi.nlm.nih.gov/gene/416006", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416006", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416006", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EANLEHW", "url": "https://omabrowser.org/oma/group/EANLEHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NY14", "url": "https://www.orthodb.org/?gene=A0A1D5NY14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A201", "url": "https://www.orthodb.org/?gene=A0A8V1A201", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A713", "url": "https://www.orthodb.org/?gene=A0A8V1A713", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9K6", "url": "https://www.orthodb.org/?gene=A0A8V1A9K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NY14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NY14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A201", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A201", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A201-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A201-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A713", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A713", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A713-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A713-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQKLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 584, "header": "tr|A0A1D5NY14-1|A0A1D5NY14_CHICK Isoform 1 of DENN domain containing 6A OS=Gallus gallus OX=9031 GN=DENND6A PE=3 SV=2 CANONICAL=A0A1D5NY14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NY14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14/entry", "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQKLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 584, "header": "tr|A0A1D5NY14-1|A0A1D5NY14_CHICK Isoform 1 of DENN domain containing 6A OS=Gallus gallus OX=9031 GN=DENND6A PE=3 SV=2 CANONICAL=A0A1D5NY14-1" }, "locus": { "chromosome": "12", "start_pos": 8934983, "end_pos": 8917325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065644.1", "url": "https://www.ensembl.org/id/ENSGALT00010065644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039910.1", "url": "https://www.ensembl.org/id/ENSGALP00010039910.1" } ] } }, { "isoform_ac": "A0A8V1A201-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A201/entry", "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQKLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 557, "header": "tr|A0A8V1A201-1|A0A1D5NY14_CHICK Computationally mapped isoform of DENN domain containing 6A OS=Gallus gallus OX=9031 GN=DENND6A PE=3 SV=1 CANONICAL=A0A1D5NY14-1" }, "locus": { "chromosome": "12", "start_pos": 8934983, "end_pos": 8917325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065647.1", "url": "https://www.ensembl.org/id/ENSGALT00010065647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039913.1", "url": "https://www.ensembl.org/id/ENSGALP00010039913.1" } ] } }, { "isoform_ac": "A0A8V1A713-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A713/entry", "sequence": { "sequence": "MVYVGTGESQVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQKLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 539, "header": "tr|A0A8V1A713-1|A0A1D5NY14_CHICK Computationally mapped isoform of DENN domain containing 6A OS=Gallus gallus OX=9031 GN=DENND6A PE=3 SV=1 CANONICAL=A0A1D5NY14-1" }, "locus": { "chromosome": "12", "start_pos": 8936278, "end_pos": 8917325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065649.1", "url": "https://www.ensembl.org/id/ENSGALT00010065649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039915.1", "url": "https://www.ensembl.org/id/ENSGALP00010039915.1" } ] } }, { "isoform_ac": "A0A8V1A9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9K6/entry", "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQVDIRYCCCIELCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQKLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 576, "header": "tr|A0A8V1A9K6-1|A0A1D5NY14_CHICK Computationally mapped isoform of DENN domain containing 6A OS=Gallus gallus OX=9031 GN=DENND6A PE=3 SV=1 CANONICAL=A0A1D5NY14-1" }, "locus": { "chromosome": "12", "start_pos": 8934983, "end_pos": 8917325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065646.1", "url": "https://www.ensembl.org/id/ENSGALT00010065646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039912.1", "url": "https://www.ensembl.org/id/ENSGALP00010039912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416006", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416006", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MSG4-1", "protein_name": "Protein DENND6A isoform X1", "gene_name": "Dennd6a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALRGPAVFGPGSRGSLDEAGAEGREAAALEAAGVALEDDDEEDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGVLMKVRIPTCHDKPGTTQMVQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQADRENLPVKPDTVAKLRTHIDAIILALPEDLQGILLKTGMT", "length": 605 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A544-1", "protein_name": "DENN domain containing 6A", "gene_name": "Dennd6a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRDQAVFGPGSRGSLDEAGAEGREAAALAAAGVALEDDEEDDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHCKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGLVMKVRIPTCHDKPGTTQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRQFLKSPNFDGWFKTRRKEMTHKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQADRENLPVKPDTVEKLRTHIDAIILALPEDLQGILLKTGMT", "length": 602 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54VA9-1", "protein_name": "Protein DENND6 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIIGGTDPLSMIFKEEEIKKQQILLEKEEKEKQEQQQKKLNKDNIFKLEEEGKKLELSTKVHIQHPNISTTSDNNSLLDPSNLTLNGKKKKWINSFCIINFDLEIGQVLDYSFPQVNFKEEESTNLCFLSFPDSNSHLQGDIIYSFKLKETSSLGNGQCNFQYGYVFFRQEKDSSISRGYLQKSVVLLSDESFVGLFKKVMEIVGPLYFDHGNTLLEVAYQNIMNWPELKLGQTYELPILGYILTFHVPHTRGTPHIIDPVVKQHQLGGGSGGGLSSSPSSSSGGGNIPTSNTTGVSPSIWSEMKLVSNLKSIDIYGCFKSFTTKLWMLWELVLLGHPLLVISPNPPMCSDSVLALVSLISPLHYCGDYRPYFTIHDTDFHKYTSFSHLSGTRPDDSNNNNNQDDSEYNNNNNNNGIPPSILGVTNPFFLKALGNWPNILTIGTTQQRLGGFKKIKSSLPNIMSKDLLTRHVLDNKEKILSEYKPFISPDKSVLKKITESADDDIINEVLRTHFLQLTQKFLIPLERYFSLLLPLAKTISIFQRPPRLKPFIKEECLNKIMETDERFIIDNKSKEIELYKQFLDCVNFKQWLDDKRAQAIKHLNILYRKAILDADIHTLLRGKPISTATDLLKRVEDQLILEENLFQTSKEIKDKFKSHIEIIRQYKNNCDNNNENNNNNILLTSPIKSTSLSSIALPPSSTTVTTKTTTTTK", "length": 715 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BH65-1", "protein_name": "Protein DENND6A", "gene_name": "Dennd6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPGPAVFGPGSRGSLDEAGAEGREAAALAAAGVALEDEEEDDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGLVMKVRIPTCHDKPGTTQMVQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGIQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRQFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQAGRESLPVKPDTVEKLRTHIDAIILALPDDLQGILLKTGMT", "length": 605 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWF6-1", "protein_name": "Protein DENND6A", "gene_name": "DENND6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRGPAGLGPGSRRPLDEAVAGAEGREAPALVAAGGAPEDDEEDDGRGRGLLRWDSFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDREKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQVDTNISVILPTVHEVDIFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPTGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQADREHLPVKPDTMEKLRTHIDAIILALPEDLQGILLKTGMT", "length": 608 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C9B4-1", "protein_name": "Polarity axis stabilization protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSRSPSFSVKPELSIKPDPESLKRWIHAFCIMRFDLEQGQLLEECYPPDCLSQEEEIEVSFNSFPDSVSQHHNRSSIHDCIFFFRFRRPKKNTEERDGSERYLYGYVFNRQRHDERLKRGGEQKSVVILSHTPYSSVFRPLLQIIGPLYFDVGNKAIEHIAGYVSMWPAPVPGKLMELPIGNAMLKVNLPPAHSLPLENGILYEESASSMAPLLPTNQSVPQGLFHDADLFGIYRGLLLQLWTLWELLLIGEPILIIAPTPPQCSEAVACLVSLVAPLFCSVDFRPYFTIHDPGFARLNSLREGDTFPPMVLGVTNIFFLKALRNIPHVVSVGTPAPNSNRVAFTSRSAGKLSVKPEGLGVQQLSLRRFSPTNLLNAVKLRRDGPLCLMTEHKEAVWTTYSAVTKPDTSILNRLIDAGMSPRVEESMSVVNNEILRRHFLELTTNFLAPFGPYFQVNAPSDGSSPYVTPPALPSFGADEFLSNLSGRGVGKFLSKRMKSNWPDLYRRFLRGPNFSPWFQRRRAVAEQEQRRLWRLARMKTDMRQITSQMNELEAVDSFNAIEKHISEEVKSLESGGGADSEGTFQKLKKDLQAVFSVLPKDMQQLLLLNPQRASLLQDPSELQ", "length": 623 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W4D1-1", "protein_name": "UDENN domain-containing protein", "gene_name": "BEST:LD39762", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSADARIKQMAPSLDTTEREREHQNVDATNSNSEPSASDWVNFSQWMHCFCVVTFDLNLGQALEHVYPPAFMPSDQEVSNICYMAFPDSNSGCMGDTKFHMRLRCTTRRDSLPGYNAECSPALRQDGSHYWGFVYFRQKRDANLPRGYFQKSFIIITRLPFFNLYYDILSQLAPRYFEEGTDVLRLASEQINRQWPGLRVGKPLQLPLLDCSYQICIPRTSSSRKSTADGGIAGGAVESPPAMAACPAAKVLASVNEIELFRSLDFVMEQLYTLWELVITAEPIVVVGTSPADCSHMVQTLLAMIAPLEYCAEARPYFTIHDSEFREFTQECSSKTTLPACILGVTNPFFVKLLKDWPHMLRLVDNQKNMQQQQHLLLGQKHARNIASATSFSSSTELGGRIALKSNTNLNGSSSSSNGSGDASSAGLHSKYRPYLKKDKALIKKVLLGMKTKRPEHVQTALIRRHLLELTQSFMIPLERYMASLMPLQKDISPFKSAPNANSFKLDDFLGTLETAGPQLTSPLKGDWKGLYRRFFRSPNFRGWYGARHRELQLTLQDLQLQALSVANLEHWAHDKQEVEIIDMILKLKQKLNLYGDKATQLEGNNGSTQQQIRAQIECMKGLLPPDLKNVVNL", "length": 634 }, "evidence": [ { "id": "A0A1D5NY14", "url": "https://omabrowser.org/oma/group/A0A1D5NY14/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell-cell adhesion mediated by cadherin", "id": "GO:2000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000049", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NY14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NY14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NY14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 584, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NY14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NY14" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYG3-1", "uniprot_ac": "A0A1D5NYG3", "uniprot_id": "A0A1D5NYG3_CHICK", "mass": { "chemical_mass": 283981.0, "monoisotopic_mass": 283981.0 }, "refseq": { "ac": "XP_015148423", "name": "filamin-B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423" }, "gene_names": [ { "name": "FLNB", "type": "recommended", "evidence": [ { "id": "A0A1D5NYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ] }, { "name": "FLNB", "type": "synonym", "evidence": [ { "id": "XP_015148423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423" } ] }, { "name": "filamin-B", "type": "synonym", "evidence": [ { "id": "XP_015148423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423" } ] } ], "protein_names": [ { "name": "Filamin B", "type": "synonym", "evidence": [ { "id": "A0A1D5NYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3/entry#names_and_taxonomy" } ] }, { "name": "filamin-B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015148423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FLNB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3", "locus": { "chromosome": "12", "start_pos": 9112477, "end_pos": 9034328, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027114", "url": "https://www.ensembl.org/id/ENSGALG00010027114" } ] } } ], "crossref": [ { "id": "ENSGALG00000005678", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21309", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21309", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "378913", "url": "https://www.ncbi.nlm.nih.gov/gene/378913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RAVPCKV", "url": "https://omabrowser.org/oma/group/RAVPCKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYG3", "url": "https://www.orthodb.org/?gene=A0A1D5NYG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9M2", "url": "https://www.orthodb.org/?gene=A0A3Q2U9M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9S9", "url": "https://www.orthodb.org/?gene=A0A8V1A9S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEP3", "url": "https://www.orthodb.org/?gene=A0A8V1AEP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N8D4", "url": "https://www.orthodb.org/?gene=F1N8D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38537:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38537:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9M2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8D4", "url": "https://www.uniprot.org/uniprotkb/F1N8D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8D4-1", "url": "https://www.uniprot.org/uniprotkb/F1N8D4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRAAGSGDLGVTIKGPKGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSKTGVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRVDETDSQGWRSPLKNSSDFPKGDPKGDTATGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMAVDADDAAVRSQETVAASPPGFRPWVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFTVKISGEGRVKESITRTRRAPSVATVGSICDLNLKIPEIDCGDMTAQVTSPSGRNSDAEIVEVDKNTYCVRFVPQEMGVHTVDVKYRGQPVPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGLQSEFFINTTKAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGNHQYNVTYVVKERGDYVLAVKWGDEHIPGSPFHVTVP", "length": 2652, "header": "tr|A0A1D5NYG3-1|A0A1D5NYG3_CHICK Isoform 1 of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=1 CANONICAL=A0A1D5NYG3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3/entry", "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRAAGSGDLGVTIKGPKGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSKTGVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRVDETDSQGWRSPLKNSSDFPKGDPKGDTATGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMAVDADDAAVRSQETVAASPPGFRPWVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFTVKISGEGRVKESITRTRRAPSVATVGSICDLNLKIPEIDCGDMTAQVTSPSGRNSDAEIVEVDKNTYCVRFVPQEMGVHTVDVKYRGQPVPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGLQSEFFINTTKAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGNHQYNVTYVVKERGDYVLAVKWGDEHIPGSPFHVTVP", "length": 2652, "header": "tr|A0A1D5NYG3-1|A0A1D5NYG3_CHICK Isoform 1 of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=1 CANONICAL=A0A1D5NYG3-1" }, "locus": { "chromosome": "12", "start_pos": 9110907, "end_pos": 9045246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065725.1", "url": "https://www.ensembl.org/id/ENSGALT00010065725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039991.1", "url": "https://www.ensembl.org/id/ENSGALP00010039991.1" } ] } }, { "isoform_ac": "A0A3Q2U9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M2/entry", "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRAAGSGDLGVTIKGPKGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSKTGVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMAVDADDAAVRSQETVAASPPGFRPWVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFTVKISGEGRVKESITRTRRAPSVATVGSICDLNLKIPEIDCGDMTAQVTSPSGRNSDAEIVEVDKNTYCVRFVPQEMGVHTVDVKYRGQPVPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGLQSEFFINTTKAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGNHQYNVTYVVKERGDYVLAVKWGDEHIPGSPFHVTVP", "length": 2622, "header": "tr|A0A3Q2U9M2-1|A0A3Q2U9M2_CHICK Computationally mapped isoform of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=1 CANONICAL=A0A1D5NYG3-1" }, "locus": { "chromosome": "12", "start_pos": 9110907, "end_pos": 9045246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065729.1", "url": "https://www.ensembl.org/id/ENSGALT00010065729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039995.1", "url": "https://www.ensembl.org/id/ENSGALP00010039995.1" } ] } }, { "isoform_ac": "A0A8V1A9S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S9/entry", "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRAAGSGDLGVTIKGPKGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSKTGVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRVDETDSQGWRSPLKNSSDFPKGDPKGDTATGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFTVKISGEGRVKESITRTRRAPSVATVGSICDLNLKIPEIDCGDMTAQVTSPSGRNSDAEIVEVDKNTYCVRFVPQEMGVHTVDVKYRGQPVPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGLQSEFFINTTKAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGNHQYNVTYVVKERGDYVLAVKWGDEHIPGSPFHVTVP", "length": 2627, "header": "tr|A0A8V1A9S9-1|A0A1D5NYG3_CHICK Computationally mapped isoform of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=1 CANONICAL=A0A1D5NYG3-1" }, "locus": { "chromosome": "12", "start_pos": 9110907, "end_pos": 9045246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065727.1", "url": "https://www.ensembl.org/id/ENSGALT00010065727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039993.1", "url": "https://www.ensembl.org/id/ENSGALP00010039993.1" } ] } }, { "isoform_ac": "A0A8V1AEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP3/entry", "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPGESCALHFQCPPCTDEMVSVGPYGSLSLESLSRVEKLMFRKLLSNLHLYVFSCALTAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGLQSEFFINTTKAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGRQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGEGAVPVTADVWRIMDN", "length": 2510, "header": "tr|A0A8V1AEP3-1|A0A1D5NYG3_CHICK Computationally mapped isoform of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=1 CANONICAL=A0A1D5NYG3-1" }, "locus": { "chromosome": "12", "start_pos": 9111172, "end_pos": 9045246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065724.1", "url": "https://www.ensembl.org/id/ENSGALT00010065724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039990.1", "url": "https://www.ensembl.org/id/ENSGALP00010039990.1" } ] } }, { "isoform_ac": "F1N8D4-1", "url": "https://www.uniprot.org/uniprotkb/F1N8D4/entry", "sequence": { "sequence": "MSTQARGQGGRRAADPDGEMPATEKDLAEDAPWKRIQQNTFTRWCNEHLRCVNKRIGNLQHDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLERESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWETWDPSKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPHGNMVKQPAIFTVDTISAGQGDLMVFVEDPEGNREEAKIMPSSDKNKTYSVQYVPKVTGPHKVSVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEATGNIANKPTYFDLYTAGAGVGDVIVEVEDPQGRCLAEVAVEDKGNQVYRCVYKPVQAGPHVVKVTFAGEAIPKTPCSVLIGEACNPNACRATGRGLQPKGVRIRETADFKVDTRAAGSGDLGVTIKGPKGLEELVKQKGFMDGVYAFEYYPATPGKYVVTITWGGHNIPKSPFEVHIGHEAGPQKVRAWGPGLHEGIVGRSADFVVESIGTEVGSLGFAIEGPSQAKIECDDKNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIRPASGDFNPDKVRAYGPGLERSGCIVNNPAEFTVETKDAGKAPLKIYAQDGEGNPIDIQMKSKPDGVFACSYVPVKPIKHTISIVWGGANVPSSPFRVLIGQGSHPQKVKVFGPGVERTGLKASEPTHFTVDCTDAGEGDVSVGIKCDARVVSDEEEDIDFDIIHNANDTFTVKYAPPAAGRYTIKVLFAGEEIPASPFRVKVDPSHDASKVKAEGPGLSKTGVENGKPTHFTVFTKGAGKAPLDVQFSSPVPGEVVTDVDIIDNYDYSHTVRYTPIQQGPMKVLVTYGGDPIPKSPFTVGVAAPLDLSKVKVNGLENRVEVGKDQEFVIDTRGAGGQGKLDVNISSPMRKAVPCLVEPVLGKECSTAKYIPREEGLYVVDVSYDGNPIPGSPYTVEATLPPDPSKVKAHGPGLRGGLVGKPAQFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDVSKVIATGPGLERGKVGEAGLLNVDCTEAGPGNLRVDMVSDTGSKAEIQIDDNKDGTYVVTYVPLSAGMYTIKMKYGGEQVPKFPARVKVEPAVDTSRVKVFGPGVEGKDVFREATTEFTVDARPLTKAGGDHIRTQITSPSGSPTDCQIQDNADGTYAVEYTPFEKGPHTVNVTYDGVPVPNSPFRVNVTEGCHPSRVKAQGPGLKEAFTNQPNAFSVVTRGAGIGGLGITVEGPSESKISCKDNKDGSCSAEYVPYVPGDYDVNITYGGEHIPGSPFKVPVKDVVDPSKVKIAGPGLGTAVRAKVPQSFTVDTSKAGVAPLEVVVAGPRGIVEPVNVVDNGDGTHTVVYTPTQEGPYMISVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGIPASLPVEFAVDAKDAGQGLLTVQITDQEGKPKRVDIHDNKDGTYTVTYVPDKTGRYTIGVKYGGDDIPSSPYRIRASPAGDASKCLATGPGIAPTVRTGEEVGFVVDAKSAGKGKVTCTVLTPDGTEAEADVVENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMAVDADDAAVRSQETVAASPPGFRPWVTEEAYVPVGDMNGMGFRPFDMVIPFAVRKGEITGEVHMPSGKTDTPDIVDNKDGTVTVRYAPTEVGLHEMHIKYMGNHIPESPLQFYVNYPNSGSVSAYGPGLIYGVANKPATFTIVTEDAEEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGNYSILVKYNDKHIPGSPFTAKITDDNRRRSQVKLGSAAEFLLDINETDLSLLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVPNSPVTIMVVQSEIGDARRARVYGRGLVEGRTFEMCDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHIPGSPFTVKISGEGRVKESITRTRRAPSVATVGSICDLNLKIPEIDCGDMTAQVTSPSGRNSDAEIVEVDKNTYCVRFVPQEMGVHTVDVKYRGQPVPGSPFQFTVGPLGEGGAHKVRAGGPGLERGETGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDHKDGSCGVSYIVQEPGNYEVSIKFNDEHIPESPYLVPIIAPSDDARRLTVTSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHSIDVKFNGSHVVGSPFKVRVGEPGQAGNPTLVTAYGPGLESGTTGQRLVTLGSANETSSIMVESVTRSSTETCYSAIPKSTSDASKVVSRGAGLSKAFVGQKSSFSVDCSKAGSNMLLVGVHGPTIPCEEVSIKHLGNHQYNVTYVVKERGDYVLAVKWGDEHIPGSPFHVTVP", "length": 2549, "header": "tr|F1N8D4-1|A0A1D5NYG3_CHICK Computationally mapped isoform of Filamin B OS=Gallus gallus OX=9031 GN=FLNB PE=1 SV=4 CANONICAL=A0A1D5NYG3-1" }, "locus": { "chromosome": "12", "start_pos": 9110907, "end_pos": 9045246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065731.1", "url": "https://www.ensembl.org/id/ENSGALT00010065731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039997.1", "url": "https://www.ensembl.org/id/ENSGALP00010039997.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXT8-1", "protein_name": "Filamin B", "gene_name": "Flnb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIESTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNSVELLVEDRGNQVYRCVYKPLQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELAVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKTGCTINNPAEFIVDPKDAGNAPLKILAQDGEGQPIDIQMKSRMDGTYVCSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASEEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPVPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGSYAVTYVPLTAGMYTLTMKYGGELVPQFPTWVKVEPTVDTSGIKAFGPGIEGKDVFREATTDFTVDARPLTQVGGDHIKAHIANPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDAPIPNSPFKVAVNEGCQPSRVHAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDTSKAGLAPLEVRVMGPRGLVEPVDVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGQVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEAGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLISVKYGGPNHISRSPFKAKVTGQRLVTPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKEKGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2602 }, "evidence": [ { "id": "A0A1D5NYG3", "url": "https://omabrowser.org/oma/group/A0A1D5NYG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MQ34-1", "protein_name": "Filamin B", "gene_name": "FLNB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKHMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEALVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLEVASNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDRGNQVYRCVYKPMQPGPHVVKVSFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGIRIRETADFKVDTKAAGSGELGVTIKGPKGLEELVKQKGFQDGVYAFEYYPSTQGKYSVSITWGGHHIQKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPFMAYIHPASGDYNPDLVQAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGDGQPIDIQMKSRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVSIGQGSHPQKVKVFGPGVERSGLKAHEPTHFTVDCTEAGEGDVSVGIKCDARVLSDEEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPTSPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFSSPGPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSRIKINGLENRVEVGKDQEFAVDTRGAGGQGKLDVTILSPSRKVVPCLVAPMAGREGSTAKFIPREEGLYAIDLTYDGHPVPGSPYVVEASLPPDPTKVKAHGPGLRGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGLLSVDCSEAGPGTLGLEAVSDSGAKAEVCIENNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPTRVKVEPAVDTSRVKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPVPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYVPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIVGPGLGSGVRARVLQSFTVDSSKAGLAPLEVRVMGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSTYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVAAVKEVPVNACPPGFRPWVTEEAYVPVSNMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTAKPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEIDSSDMSAHVTSPSGRVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYVVPVIAPSDDARRLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGSTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFLGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2602 }, "evidence": [ { "id": "A0A1D5NYG3", "url": "https://omabrowser.org/oma/group/A0A1D5NYG3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HFM4-1", "protein_name": "Filamin-B isoform X1", "gene_name": "Flnb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAHVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDINVEVEDPQGKNTVELLVEDRGNQVYRCVYKPLQPGPHVIKVSFAGDAIPKSPFGVQVGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSIAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCIVNNPAEFIVDPKDAGKAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPVKAIKHTIAVVWGGVSIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIQVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLDVQFSSLLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTKGAGGQGKLDVTILSPSRKVVPCLVAPVAGRESSTAKFIPREEGLFAVDITYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLQGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKAGEAGLLSVDCSEAGPGTLDLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPTRVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSRSLTQVGGDHIKAHIANPSGASTECFVKDNADGTYQVEYTPFEKGFHLVEVTYDDVPIPNSPFKVIVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPAKDVVDPSKVKVAGPGLGSGVRARILQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVMDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDSKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPIVKTGEEVGFVVDAKTAGKGKVTCTILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEKAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKITGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPVGKNSHCVRFVPQEMGVHTVSVKYHGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLEGGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLIGVKYGGPNHIMRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2602 }, "evidence": [ { "id": "A0A1D5NYG3", "url": "https://omabrowser.org/oma/group/A0A1D5NYG3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75369-1", "protein_name": "Filamin-B", "gene_name": "FLNB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2602 }, "evidence": [ { "id": "A0A1D5NYG3", "url": "https://omabrowser.org/oma/group/A0A1D5NYG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80X90-1", "protein_name": "Filamin-B", "gene_name": "Flnb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP", "length": 2602 }, "evidence": [ { "id": "A0A1D5NYG3", "url": "https://omabrowser.org/oma/group/A0A1D5NYG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYG3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1324, "end_pos": 1326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1340, "end_pos": 1342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1937, "end_pos": 1939, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1981, "end_pos": 1983, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2412, "end_pos": 2414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2458, "end_pos": 2460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2533, "end_pos": 2535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2620, "end_pos": 2622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYG3" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 141, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 538 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1324, "end_pos": 1326 }, { "start_pos": 1340, "end_pos": 1342 }, { "start_pos": 1417, "end_pos": 1419 }, { "start_pos": 1497, "end_pos": 1499 }, { "start_pos": 1937, "end_pos": 1939 }, { "start_pos": 1981, "end_pos": 1983 }, { "start_pos": 2412, "end_pos": 2414 }, { "start_pos": 2458, "end_pos": 2460 }, { "start_pos": 2533, "end_pos": 2535 }, { "start_pos": 2620, "end_pos": 2622 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 823, "end_pos": 825 }, { "start_pos": 98, "end_pos": 100 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYI1-1", "uniprot_ac": "A0A1D5NYI1", "uniprot_id": "A0A1D5NYI1_CHICK", "mass": { "chemical_mass": 20076.0, "monoisotopic_mass": 20076.0 }, "refseq": { "ac": "XP_001231345", "name": "baculoviral IAP repeat-containing protein 5.1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345" }, "gene_names": [ { "name": "LOC768589", "type": "recommended", "evidence": [ { "id": "A0A1D5NYI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ] }, { "name": "LOC768589", "type": "synonym", "evidence": [ { "id": "XP_001231345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A1D5NYI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1/entry#names_and_taxonomy" } ] }, { "name": "baculoviral IAP repeat-containing protein 5.1", "type": "synonym", "evidence": [ { "id": "XP_001231345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_001231345.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC768589", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1", "locus": {} } ], "crossref": [ { "id": "A0A1D5NYI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037678", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768589", "url": "https://www.ncbi.nlm.nih.gov/gene/768589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768589", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMLEMTR", "url": "https://omabrowser.org/oma/group/YMLEMTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYI1", "url": "https://www.orthodb.org/?gene=A0A1D5NYI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46771:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46771:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVLLKDLVSSSKLLSDFKEMYDYENRLKTFTNWPFVENCKCTPENMAKAGFIHCPSANETDVAKCFFCLIELEGWEPNDDPWEEHTKRRSCGFLSLTKQFDDLTMEEYYMLEMTRLRTFLCKTGRSIINSFEEEVAATRKRLVDNFVSSHQYTPQPPVPIQADPTCPPSESS", "length": 173, "header": "tr|A0A1D5NYI1-1|A0A1D5NYI1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC768589 PE=3 SV=1 CANONICAL=A0A1D5NYI1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1/entry", "sequence": { "sequence": "MEVLLKDLVSSSKLLSDFKEMYDYENRLKTFTNWPFVENCKCTPENMAKAGFIHCPSANETDVAKCFFCLIELEGWEPNDDPWEEHTKRRSCGFLSLTKQFDDLTMEEYYMLEMTRLRTFLCKTGRSIINSFEEEVAATRKRLVDNFVSSHQYTPQPPVPIQADPTCPPSESS", "length": 173, "header": "tr|A0A1D5NYI1-1|A0A1D5NYI1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC768589 PE=3 SV=1 CANONICAL=A0A1D5NYI1-1" }, "locus": { "chromosome": "7", "start_pos": 9296954, "end_pos": 9293736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026066.1", "url": "https://www.ensembl.org/id/ENSGALT00010026066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014706.1", "url": "https://www.ensembl.org/id/ENSGALP00010014706.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768589", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 173, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYI1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYI4-1", "uniprot_ac": "A0A1D5NYI4", "uniprot_id": "A0A1D5NYI4_CHICK", "mass": { "chemical_mass": 88865.0, "monoisotopic_mass": 88865.0 }, "refseq": { "ac": "XP_421358", "name": "HHIP-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358" }, "gene_names": [ { "name": "HHIPL1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4" } ] }, { "name": "HHIPL1", "type": "synonym", "evidence": [ { "id": "XP_421358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358" } ] } ], "protein_names": [ { "name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "type": "recommended", "evidence": [ { "id": "A0A1D5NYI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4/entry#names_and_taxonomy" } ] }, { "name": "HHIP-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_421358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_421358.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358" } ] }, { "annotation": "Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4#function" }, { "database": "UniProtKB", "id": "ARBA00058074", "url": "https://www.uniprot.org/uniprotkb/ARBA00058074#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HHIPL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4", "locus": {} } ], "crossref": [ { "id": "A0A1D5NYI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036286", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423448", "url": "https://www.ncbi.nlm.nih.gov/gene/423448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423448", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423448", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSVEVRY", "url": "https://omabrowser.org/oma/group/YSVEVRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYI4", "url": "https://www.orthodb.org/?gene=A0A1D5NYI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYI4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRALRGAALALLLAAALGPGPGRPHPQCLDFKPPFRPPRALAFCRRYGAFGCCDARRDRALLQRFYRLSAHLDGPTYAACAGHLQDLLCQECSPYAAHLYDAEDPSTPVRTIPGLCQDYCQQVWQKCRSIFHYLSTDQELIALENNMAKFCRYLSLEDTDYCFPHLLANENLNQNLGLVTADAEGCLQLCLMEVANGLRNPVAMVHANDGTHRFFIAEQVGLVWAYLPDRSRLEKPFLNISEAVLTSPWEGDERGFLGIVFHPKFKFTGKVYVYYSVEVRYEERIRISEFRISSGDMNTVDHGSERIILEIEEPASNHNGGELLFGDDGYLYIFTGDGGMAGDPFGTFGNAQNKSALLGKVLRIDVNNNDRGPVYRIPPDNPFVDDPQARPEVYAYGVRNMWRCSFDRGEPDTKEGKGRLFCGDVGQNKYEEIDIVEKGKNYGWRAREGFSCYDKKLCVNSSLDDVLPIYAYPHKMGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMSLKEDRATGEWQYSEICMGTGQTCMFPGLINNYYQYIISFAEDEAGELYFMSTGVPSATAPHGVVYKVVDTSRRAPPGKCQVEPLPVKVKSKLVKFVPKEKLIVKTPTPRPRLKTTTEAPRRGWPDHATPHTSALDRVDQAPVNRSVMLVPATAPSPRPGKGERKGQRRKKKPRNGAVRLMDGGSRGRSWGRVEVYVDGEWGTVCDDGWSSAAAAVVCRQLGFPYVVRASKKAEFGEGTLLRILLDDVQCSGQEKTLLECAHAEVGTHNCSHEEDAGVVCSREEVADW", "length": 797, "header": "tr|A0A1D5NYI4-1|A0A1D5NYI4_CHICK Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Gallus gallus OX=9031 GN=HHIPL1 PE=3 SV=1 CANONICAL=A0A1D5NYI4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4/entry", "sequence": { "sequence": "MRALRGAALALLLAAALGPGPGRPHPQCLDFKPPFRPPRALAFCRRYGAFGCCDARRDRALLQRFYRLSAHLDGPTYAACAGHLQDLLCQECSPYAAHLYDAEDPSTPVRTIPGLCQDYCQQVWQKCRSIFHYLSTDQELIALENNMAKFCRYLSLEDTDYCFPHLLANENLNQNLGLVTADAEGCLQLCLMEVANGLRNPVAMVHANDGTHRFFIAEQVGLVWAYLPDRSRLEKPFLNISEAVLTSPWEGDERGFLGIVFHPKFKFTGKVYVYYSVEVRYEERIRISEFRISSGDMNTVDHGSERIILEIEEPASNHNGGELLFGDDGYLYIFTGDGGMAGDPFGTFGNAQNKSALLGKVLRIDVNNNDRGPVYRIPPDNPFVDDPQARPEVYAYGVRNMWRCSFDRGEPDTKEGKGRLFCGDVGQNKYEEIDIVEKGKNYGWRAREGFSCYDKKLCVNSSLDDVLPIYAYPHKMGKSVTGGYVYRGCESPNLNGLYIFGDFMSGRLMSLKEDRATGEWQYSEICMGTGQTCMFPGLINNYYQYIISFAEDEAGELYFMSTGVPSATAPHGVVYKVVDTSRRAPPGKCQVEPLPVKVKSKLVKFVPKEKLIVKTPTPRPRLKTTTEAPRRGWPDHATPHTSALDRVDQAPVNRSVMLVPATAPSPRPGKGERKGQRRKKKPRNGAVRLMDGGSRGRSWGRVEVYVDGEWGTVCDDGWSSAAAAVVCRQLGFPYVVRASKKAEFGEGTLLRILLDDVQCSGQEKTLLECAHAEVGTHNCSHEEDAGVVCSREEVADW", "length": 797, "header": "tr|A0A1D5NYI4-1|A0A1D5NYI4_CHICK Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Gallus gallus OX=9031 GN=HHIPL1 PE=3 SV=1 CANONICAL=A0A1D5NYI4-1" }, "locus": { "chromosome": "5", "start_pos": 47667356, "end_pos": 47650813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039496.1", "url": "https://www.ensembl.org/id/ENSGALT00010039496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022789.1", "url": "https://www.ensembl.org/id/ENSGALP00010022789.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423448", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423448", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A9N1-1", "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "Hhipl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARQRTVAGIGPGALLALRALLVAAHPQCLDFRPPFRPPQPLSFCAQYSAFGCCTAEQDAALARRFRALETRMDAGVWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQTCRGLFRHLSPDRELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDRSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPRFPHPSKLYVYYSVGVGFREWIRISEFRISEDDENTVDHGSERIILEIEEPASNHNGGQLLFGDDGFLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRKERGLPYGIPLDNPFVDDPEARPEVYALGVRNMWRCSFDRGDPVSGTHRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPESGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVTDPSRRAPPGKCKIRPAQVKVKSHLIPFVPKEKFIRTSESTPRPTARAPTKAPRRRRPTAAPPAPTLRPTKPARPTRRPGARKGGGRRRGRPGTAVPEPQNGSVRLVRPSGLSPGRGRVEVFIGGRWGTVCDDGWDIKAAAVVCRQLGFAHAVRAAKRAEFGEGRALRILLDDVRCAGSERNLLECAHAGVGTHNCKHEEDAGVECSHEDPDL", "length": 791 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MI35-1", "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "HHIPL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGRRAGAGAGAGTLLALLVLRALGAAAHPQCLDFRPPFRPPQPLRFCSQYSAFGCCTPEQDAALARRFGAVAARVDAAMWAECAGYALDLLCQECSPYVAHLYDAEDPSTPLRTVPGLCEDYCLDMWQTCRGLFRHLSPDRELWALEGNRAKLCRSLSLDDTDYCFPRLLVNENLNSNLGRVVADAEGCLQLCLEEVANGLRNPVAMVHARDGTHRFFVAEQLGLVWVYLPDRSRLEKPFLNISRAVLTSPWEGDERGFLGLAFHPSFRHNGKLYVYYSVGVGFDEWIRISEFRVSEDDVNAVDHDSERIILEIEEPASNHNGGQLLFGDDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPLYRIPPDNPFVGDPAARPEVYAFGVRNMWRCSFDRGDPATGAGRGRLFCGDVGQNKFEEVDLVERGRNYGWRAREGYQCYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYVFGDFMSGRLMSLRENPETGQWRYSEICMGRGQTCAFPGLINNYYPHIISFGEDEAGELYFMSTGMPSATVAHGVVYKMIDPSRRAPPGKCQIQPSRVKVRSRLIHFVPKEKFIRRTESTPRPTKAPRRSRPTAAPPAPTPRPPRPTSRPGRRRGSGRRRGRLGTADPEPSNGAVRLVRPAGLSPGRGRVEVFAGGRWGTVCDDAWDTKAAAVVCRQLGFLYAARAAKRAEFGEGRTLPILLDDVRCTGSERNLLECAHAGLGSHNCGHQEDAGVVCSREDPDL", "length": 786 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6PEI8-1", "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "hhipl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWYFCDVFGRIWQPPFILFYLSAFWIAPAILHPQCLDFKPPFQPQQELQFCQMYKNFGCCDYARDQELMKKYYRVMDNFDYYGYSNCASYVQDLLCQECSPYAAHLFDAEDPSTPLRTIPGLCPDYCAQFHSKCRSFLTLLSDDPRLAELEHDQRKLCQYLELDDPDYCYPHLLSNEHLNKNLGRTAADSEGCLQLCLEEVANGLRNPLAMVHANDGTHRFFVAEQVGLVWVYLPDQSKLEKPFLNITKAVLTSPWEGDERGFLGLTFHPRFKYNGKLYVYYSVEVGFDERIRISEFRISSTDMNVVDHTSERIILEIDEPASNHNGGQLLFADDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDDNERGPLYRIPADNPFVHEPKARPEVYAYGVRNMWRCSVDRGDPITKEGRGRIFCGDVGQNKYEEVDIVEKGRNYGWRAKEGFSCYDKKLCANSSLDDVLPIYAYPHKMGKSVTGGYVYRGCENPNLNGLYIFGDFMSGRLMSLKENRQTGNWEYNEICMGIGLTCSFPGLINNYYPYIISFAEDEAGELYFMSTEIPSATSPTGVVYKIVDPSRRAPPGKCHYEPHSVRVKSNIIPFEPKETLIGVHIPTKQPKLSNTEEPPLVTTKDWLRELLDNFREEDGQITTTPFTPTTPKPVRTSRQRKGRRRKGKHKNGAVRLVGDEEGQRDRGRVEVYANGEWGTVCDDLWNTKNAVVVCRQLGFLHALKAAKHAEFGEGTGLKIILDDVQCEGTEETLLDCQHAGIGTHNCAHYEDAGVVCGNSVASLQ", "length": 802 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LHD8-1", "protein_name": "HHIP like 1", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRAGAGAGALLALLALRALGASAHPQCLDFRPPFRPPQPLHFCAQYSAFGCCAPEHDAALARRFGALAARVDPALWAECAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQTCRGLIRHLSPDRELWALEGNRAKFCRYLSLDDVDYCFPRLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHARDGTHRFFVAEQLGLVWAYLPDRSRLEKPFLNISRAVLTSPWEGDERGFLGLAFHPRFRHNGKLYVYYSVGVDFHEWIRISEFRVSEDDVNTVDHDSERIILEIEEPASNHNGGQLLFGDDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPLYHIPPDNPFVGDPAARPEVYAFGVRNMWRCSFDRGDPASGAGRGRLFCGDVGQNKFEEVDLVERGRNYGWRAREGFECYDRKLCANTSLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENLGTGQWRYSEICMGRGQTCAFPGLINNYYPHVISFAEDEAGELYFMSTGVPSATVARGVVYKMIDPSRRAPPGKCQIQPAHVRLRSRLVPFVPKEKFIRRTESTPRPTARAPTTKAPRRSRPTAAPLAPTPRPARPTGRPGRRRGGGRRRGRPGTADPAPSNGAVRLVRPAGLSPGRGRVEVFAGGRWGTVCDDAWDTKAATVVCRQLGFAYAVRAAKRAEFGEGRALPILLDDVRCEGSERNLLECAHAGLGSHNCGHQEDAGVVCSREDPDL", "length": 789 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14DK5-1", "protein_name": "HHIP-like protein 1", "gene_name": "Hhipl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRRAVARIGPGALLVLRALLAAAHPQCLDFRPPFRPPQPLSFCAQYSAFGCCTAEQDAALARRFRVLETRMDAGVWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQTCRGLFRLLSPDRELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDRSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPRFPHPSKLYVYYSVGVGFREWIRISEFRVSEGDENTVDHGSERIILEIEEPASNHNGGQLLFGDDGFLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRKERGLHYGIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANTSLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAAHGVIYKVIDPSRRAPPGKCKIRPAQVKVRSHLIPFVPKEKFIRTPESTPRPTARAPTKAPRRRRPTAAPPAPTPRPTKPARPTRRPGARKGGGRRRGRPSTAVPEPENGSVRLVRPAGLSPGRGRVEVFIGGRWGTVCDDAWDTKAAAVVCRQLGFAHAVRAAKRAEFGEGRALRILLDDVRCAGSERNLLECAHAGVGTHNCKHDEDAGVECSHQDPNL", "length": 791 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JK4-1", "protein_name": "HHIP-like protein 1", "gene_name": "HHIPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARARAGALLALWVLGAAAHPQCLDFRPPFRPTQPLRLCAQYSDFGCCDEGRDAELTRRFWALASRVDAAEWAACAGYARDLLCQECSPYAAHLYDAEDPFTPLRTVPGLCQDYCLDMWHKCRGLFRHLSTDQELWALEGNLARFCRYLSLDDTDYCFPYLLVNKNLNSNLGHVVADAKGCLQLCLEEVANGLRNPVAMVHARDGTHRFFVAEQVGLVWAYLPDRSRLGKPFLNISRVVLTSPWEGDERGFLGIAFHPSFQHNRRLYVYYSVGIRSSEWIRISEFRVSEDDENAVDHSSERIILEVKEPASNHNGGQLLFGDDGYLYIFTGDGGMAGDPFGTFGNAQNKSALLGKVLRIDVDRKERGLPYGIPPDNPFVGDPAAQPEVYALGVRNMWRCSFDRGDPSSGTGRGRLFCGDVGQNKFEEVDVVERGGNYGWRAREGFECYDRSLCANTSLNDLLPIFAYPHTVGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLQENPGTGQWQYSEICMGHGQTCEFPGLINNYYPYIISFGEDEAGELYFMSTGEPSATAPRGVVYKIIDASRRAPPGKCQIQPAQVKIRSRLIPFVPKEKFIPKTRSTPRPTARAPTRAPRRGRPTAAPPAPTPRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNPDL", "length": 782 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SSG3-1", "protein_name": "HIPL1 protein", "gene_name": "HIPL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKLHQFLVFLFLFLSCFALSSWALPLCSDSRAPSEVNSTLSFCPYKGKTCCNTMKDTSLMKQFQAMNISDKGCASVVKSILCANCDPFSSDLFRDNSDQQSVPILCNSTSSANSTENFCSETWETCQNVSISGSLFAASLQGRAGAPSNKNASKLADLWQSKTDFCSAFGGASSNETVCFSGEPVALNDNDTTPDKPPSGICLEKIGNGSYLNMVPHPDGSNRAFFSTQPGIVFLAGIPDQDSGGVLDVDPSSPFVDMTDEIHFDTEFGMMGMAFHPKFAQNGRFFASFNCDKSKWPGCTGRCSCNSDVNCDPSKLTPDSGSQPCQYQTVIAEYTANSTSSDPSKAKNAKPTEVRRIFTMGLPFTSHHAGQILFGPDGYLYFMMGDGGGGADPYNFAQNKKSLLGKIMRLDVDNIPSASEISKMGLWGNYSIPKDNPFREDKELEPEIWAVGLRNPWRCSFDSSRPSYFMCADVGQDTYEEVDLISKGGNYGWRVYEGPDLFHPESSPGGNTSVKSLNPIFPVMGYNHSEVDSSGKSASITGGYFYRSETDPCIAGRYVYADLYGNGVWAGIETPANSGSFVTKRTTFSCASDSPMKCSDSPGTSGLSLGYVFSFGEDNNKDIYLLTSNGVYRVVRPSRCNLTCSKENSTARRNPGTSSSPSSSSSSCYKHINGFHGSLVVLFVSLSLILLGLLN", "length": 695 }, "evidence": [ { "id": "A0A1D5NYI4", "url": "https://omabrowser.org/oma/group/A0A1D5NYI4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYI4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 797, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYI4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NYI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYI4" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 687, "end_pos": 790, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 778, "end_pos": 780 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYL9-1", "uniprot_ac": "A0A1D5NYL9", "uniprot_id": "A0A1D5NYL9_CHICK", "mass": { "chemical_mass": 39373.0, "monoisotopic_mass": 39373.0 }, "refseq": { "ac": "NP_001186450", "name": "leucine zipper protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450" }, "gene_names": [ { "name": "LUZP2", "type": "recommended", "evidence": [ { "id": "A0A1D5NYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9" } ] }, { "name": "LUZP2", "type": "synonym", "evidence": [ { "id": "NP_001186450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450" } ] } ], "protein_names": [ { "name": "Leucine zipper protein 2", "type": "synonym", "evidence": [ { "id": "A0A1D5NYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper protein 2", "type": "synonym", "evidence": [ { "id": "NP_001186450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: HAEK01001471.1, HAEK01040797.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN08016554, SAMN08016668 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Dec 9, 2010 this sequence version replaced XP_420933.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001186450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LUZP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9", "locus": { "chromosome": "5", "start_pos": 1288533, "end_pos": 1451805, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022724", "url": "https://www.ensembl.org/id/ENSGALG00010022724" } ] } } ], "crossref": [ { "id": "A0A1D5NYL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030151", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030151", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423001", "url": "https://www.ncbi.nlm.nih.gov/gene/423001", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423001", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423001", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGKTCSM", "url": "https://omabrowser.org/oma/group/EGKTCSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYL9", "url": "https://www.orthodb.org/?gene=A0A1D5NYL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AYM6", "url": "https://www.orthodb.org/?gene=A0A3Q3AYM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZJA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPM8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRH8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22414:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22414:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001186450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AYM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AYM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AYM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AYM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFLPAYYLLPLFPALVFSTRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDVGKTCLGNYNNSTSHLKMEETETSLQQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 344, "header": "tr|A0A1D5NYL9-1|A0A1D5NYL9_CHICK Isoform 1 of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYL9/entry", "sequence": { "sequence": "MKFLPAYYLLPLFPALVFSTRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDVGKTCLGNYNNSTSHLKMEETETSLQQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 344, "header": "tr|A0A1D5NYL9-1|A0A1D5NYL9_CHICK Isoform 1 of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1413481, "end_pos": 1289072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055276.1", "url": "https://www.ensembl.org/id/ENSGALT00010055276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033450.1", "url": "https://www.ensembl.org/id/ENSGALP00010033450.1" } ] } }, { "isoform_ac": "A0A3Q3AYM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AYM6/entry", "sequence": { "sequence": "MKFLPAYYLLPLFPALVFSTRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDVGKTCLGNYNNSTSHLKMEETETSLQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 343, "header": "tr|A0A3Q3AYM6-1|A0A1D5NYL9_CHICK Computationally mapped isoform of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1413481, "end_pos": 1289072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055270.1", "url": "https://www.ensembl.org/id/ENSGALT00010055270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033445.1", "url": "https://www.ensembl.org/id/ENSGALP00010033445.1" } ] } }, { "isoform_ac": "A0A8V0ZJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA8/entry", "sequence": { "sequence": "MKFLPAYYLLPLFPALVFSTRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDDPTHDLLISCQTNFRLARHVWGITIIQHLI", "length": 313, "header": "tr|A0A8V0ZJA8-1|A0A8V0ZJA8_CHICK Computationally mapped isoform of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1413481, "end_pos": 1289702, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055258.1", "url": "https://www.ensembl.org/id/ENSGALT00010055258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033438.1", "url": "https://www.ensembl.org/id/ENSGALP00010033438.1" } ] } }, { "isoform_ac": "A0A8V0ZPM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM8/entry", "sequence": { "sequence": "MCACSASTRSQQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDVGKTCLGNYNNSTSHLKMEETETSLQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 333, "header": "tr|A0A8V0ZPM8-1|A0A8V0ZPM8_CHICK Computationally mapped isoform of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1364067, "end_pos": 1289072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055255.1", "url": "https://www.ensembl.org/id/ENSGALT00010055255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033435.1", "url": "https://www.ensembl.org/id/ENSGALP00010033435.1" } ] } }, { "isoform_ac": "A0A8V0ZPN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN4/entry", "sequence": { "sequence": "MKFLPAYYLLPLFPALVFSTRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKVGKTCLGNYNNSTSHLKMEETETSLQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 314, "header": "tr|A0A8V0ZPN4-1|A0A8V0ZPN4_CHICK Computationally mapped isoform of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1413481, "end_pos": 1289072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055262.1", "url": "https://www.ensembl.org/id/ENSGALT00010055262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033440.1", "url": "https://www.ensembl.org/id/ENSGALP00010033440.1" } ] } }, { "isoform_ac": "A0A8V0ZRH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH8/entry", "sequence": { "sequence": "MEVRQGYEELERQLKEVFKERSNILRQLSKTSKELEGIKVNLQSLKNDEASARSDVQKLLELGQKQREEMKSLQEAFQKQLNEAVEKAEKQQATINFLKTEMERKSRMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLIFKAQRLTDLEQKLAAAKDELEKAALDKESQLKALKDTVQLCLSSVLHNQPPTIHRIPPKPAEKLTSSATKGSKVQFPVINPKQNASAEKESLHVASRKEENQSVQECDSQDVGKTCLGNYNNSTSHLKMEETETSLQMLRNPPWTKPEDKKPPERSEKKFEDSVGTKEKKL", "length": 326, "header": "tr|A0A8V0ZRH8-1|A0A8V0ZRH8_CHICK Computationally mapped isoform of Leucine zipper protein 2 OS=Gallus gallus OX=9031 GN=LUZP2 PE=1 SV=1 CANONICAL=A0A1D5NYL9-1" }, "locus": { "chromosome": "5", "start_pos": 1362961, "end_pos": 1289072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055252.1", "url": "https://www.ensembl.org/id/ENSGALT00010055252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033432.1", "url": "https://www.ensembl.org/id/ENSGALP00010033432.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423001", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M2U4-1", "protein_name": "Leucine zipper protein 2", "gene_name": "Luzp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQTSKTDVQKLLELGQKQREEMKSLQEALQNQLRETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKTKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPLSLSPSNPTQMLHQPRTIASKIPDSRTKSKPQKSSPGIHESSRVQATKEEKRRTSVCGPQDEGSSCLVKHEEGPQRNITAESEPATQKLQMPLCSECEEKKGSEKQSATFDGIPAREEKIL", "length": 345 }, "evidence": [ { "id": "A0A1D5NYL9", "url": "https://omabrowser.org/oma/group/A0A1D5NYL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LVF4-1", "protein_name": "Leucine zipper protein 2", "gene_name": "Luzp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQSSKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLSSVFRDQPPPLSLFPSNPTQMLHPPRTIASRIPETRTKSKPQQSSPGHHDSSQVQATKEESRRTTVCGTQDEGSSCLAKHEEGPKSNNTAESELTTQKLQMPLCSECEEKKVPEKTSASFDGTPAREEKLL", "length": 345 }, "evidence": [ { "id": "A0A1D5NYL9", "url": "https://omabrowser.org/oma/group/A0A1D5NYL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5D8S1-1", "protein_name": "Leucine zipper protein 2", "gene_name": "luzp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFIGAVYLLFLLPALSFNSSYEGLEKKLKEVFTERTGILRHLSKTSKELDSIKGNLQSLKNEDAVPKKDVQRILELSHKQRDEMKSLQAALQKQLDDAAERAEKQQATIKFLKMEMEKKTKIIKDLQQENKSLKNKLLSGNKLCDIHAEESKKIQAQLKELRYGKKDLIFKGQQLMDLENKLKVAKDELEKAALDKESQLKALKDTVHICFSSVLHSQTASLHRFPATPTNLLRYSALVNNSRVTFQQPHMKDIPKVPRITTTSKLPVSSAVMRRESTGPKDCQMVKVGSDCSHNQTESSSVMKKTFGHSQSKTPEQNGQGQARTAEESVKTDGELKKTQSDKHN", "length": 346 }, "evidence": [ { "id": "A0A1D5NYL9", "url": "https://omabrowser.org/oma/group/A0A1D5NYL9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86TE4-1", "protein_name": "Leucine zipper protein 2", "gene_name": "LUZP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPSNATAETEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL", "length": 346 }, "evidence": [ { "id": "A0A1D5NYL9", "url": "https://omabrowser.org/oma/group/A0A1D5NYL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGY3-1", "protein_name": "Leucine zipper protein 2", "gene_name": "Luzp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQSSKTDVQKLLELGQRQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLSSVFRDQPPPLSLMPSNPTQMLHPPRTVASRIPEARTKSKPQPSSPGHHDSSQVQATKEESRRPSVCGPQDEGSSCLVKHEEGPQSNSTAESELTTQKLQMPICSECEEKKGPENPSASFDGTPAREEKLL", "length": 345 }, "evidence": [ { "id": "A0A1D5NYL9", "url": "https://omabrowser.org/oma/group/A0A1D5NYL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYL9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 294, "end_pos": 296 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYN9-1", "uniprot_ac": "A0A1D5NYN9", "uniprot_id": "A0A1D5NYN9_CHICK", "mass": { "chemical_mass": 22862.0, "monoisotopic_mass": 22862.0 }, "refseq": { "ac": "XP_015140414", "name": "testis development-related protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414" }, "gene_names": [ { "name": "TDRP", "type": "recommended", "evidence": [ { "id": "A0A1D5NYN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9" } ] }, { "name": "TDRP", "type": "synonym", "evidence": [ { "id": "XP_015140414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414" } ] } ], "protein_names": [ { "name": "Testis development related protein", "type": "synonym", "evidence": [ { "id": "A0A1D5NYN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9/entry#names_and_taxonomy" } ] }, { "name": "testis development-related protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TDRP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9", "locus": { "chromosome": "3", "start_pos": 91328124, "end_pos": 91300956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003703", "url": "https://www.ensembl.org/id/ENSGALG00010003703" } ] } } ], "crossref": [ { "id": "A0A1D5NYN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016356", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421905", "url": "https://www.ncbi.nlm.nih.gov/gene/421905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421905", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGHCFWD", "url": "https://omabrowser.org/oma/group/KGHCFWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYN9", "url": "https://www.orthodb.org/?gene=A0A1D5NYN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35663:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35663:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKLNKSSKVLLDDSPEEEETRPRGPLPPAAAFAAPQNKDQFLHDEVPSSVSQLATKVQGASFRGWKEVTSMFNKDDEQQLLAGCKSPKSKGTNLKLKEEMKSEKKPGFWDSLVIKQNVQSRKPDEIEGWEPPQITAADSASDAATALNDYSAWSGWEDETKGSTKYTNLASSGNSSRWSIKSAGKLVSIRRQSKGNLTDNWEELE", "length": 206, "header": "tr|A0A1D5NYN9-1|A0A1D5NYN9_CHICK Isoform 1 of Testis development related protein OS=Gallus gallus OX=9031 GN=TDRP PE=4 SV=3 CANONICAL=A0A1D5NYN9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9/entry", "sequence": { "sequence": "MWKLNKSSKVLLDDSPEEEETRPRGPLPPAAAFAAPQNKDQFLHDEVPSSVSQLATKVQGASFRGWKEVTSMFNKDDEQQLLAGCKSPKSKGTNLKLKEEMKSEKKPGFWDSLVIKQNVQSRKPDEIEGWEPPQITAADSASDAATALNDYSAWSGWEDETKGSTKYTNLASSGNSSRWSIKSAGKLVSIRRQSKGNLTDNWEELE", "length": 206, "header": "tr|A0A1D5NYN9-1|A0A1D5NYN9_CHICK Isoform 1 of Testis development related protein OS=Gallus gallus OX=9031 GN=TDRP PE=4 SV=3 CANONICAL=A0A1D5NYN9-1" }, "locus": { "chromosome": "3", "start_pos": 91325260, "end_pos": 91301075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008545.1", "url": "https://www.ensembl.org/id/ENSGALT00010008545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005001.1", "url": "https://www.ensembl.org/id/ENSGALP00010005001.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421905", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IDJ7-1", "protein_name": "Uncharacterized protein LOC564539", "gene_name": "si:ch211-225h24.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKKSKSKVLVDEASEEDEVSWHNEHAGKDKDSEGTEEVLSPTTKDSKLKKVKSKREKGDKKLFPSQDDEHILLTGVTVSHRRGSAKKNWEDDKIKTHPEKDKAHCLWDSISTTMKQITPTRKMDRMEGWEPPQLTDGQMEEDKTELEKKRSDSSPLSSPLSLSLPHSLGLPSWVGLGLEEDSSRYASLTESQTGGPAQWAARARDKFAAVRRRSPANLSESTWEGLK", "length": 228 }, "evidence": [ { "id": "A0A1D5NYN9", "url": "https://omabrowser.org/oma/group/A0A1D5NYN9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q498E2-1", "protein_name": "Testis development-related protein", "gene_name": "Tdrp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWKLSRSRVLLDEPPEEEDVLRGASPASAAAQAPGASLRGWKEATSLFNKDDEERLLETSRSSKSKGTNVRLKEELKAEKKSGFWDALVLKQNVQPKKPDQMEGWEPPKLTAEDVATDHTEDGISSLPPWSAWEDDTKGSTKYTSLASSASSSRWSLRSAGKLVSIRRQSKGHLTETCEEVE", "length": 182 }, "evidence": [ { "id": "A0A1D5NYN9", "url": "https://omabrowser.org/oma/group/A0A1D5NYN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86YL5-1", "protein_name": "Testis development-related protein", "gene_name": "TDRP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKLGRGRVLLDEPPEEEDGLRGGPPPAAAAAAQAQVQGASFRGWKEVTSLFNKDDEQHLLERCKSPKSKGTNLRLKEELKAEKKSGFWDNLVLKQNIQSKKPDEIEGWEPPKLALEDISADPEDTVGGHPSWSGWEDDAKGSTKYTSLASSANSSRWSLRAAGRLVSIRRQSKGHLTDSPEEAE", "length": 185 }, "evidence": [ { "id": "A0A1D5NYN9", "url": "https://omabrowser.org/oma/group/A0A1D5NYN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C5P7-1", "protein_name": "Testis development-related protein", "gene_name": "Tdrp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWKLSRSRVLLDEPPEEEDVLRGAPPASAAAPASGASLRGWKEATSLFNKDDEEHLLETSRSPKSKGTNQRLREELKAEKKSGFWDALVLKQNAQPKKPDQIEGWEPPKLTAEDVVADHTEDDRSGCPPWSAWEDDTKGSTKYTSLANSASSSRWSLRSAGKLVSIRRQSKGHLTETCEEGE", "length": 182 }, "evidence": [ { "id": "A0A1D5NYN9", "url": "https://omabrowser.org/oma/group/A0A1D5NYN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYN9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYN9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYN9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NYR7-1", "uniprot_ac": "A0A1D5NYR7", "uniprot_id": "A0A1D5NYR7_CHICK", "mass": { "chemical_mass": 84846.0, "monoisotopic_mass": 84846.0 }, "refseq": { "ac": "NP_001074332", "name": "cyclin-D-binding Myb-like transcription factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332" }, "gene_names": [ { "name": "DMTF1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ] }, { "name": "DMTF1", "type": "synonym", "evidence": [ { "id": "NP_001074332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332" } ] } ], "protein_names": [ { "name": "Cyclin-D-binding Myb-like transcription factor 1", "type": "recommended", "evidence": [ { "id": "A0A1D5NYR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7/entry#names_and_taxonomy" } ] }, { "name": "cyclin-D-binding Myb-like transcription factor 1", "type": "synonym", "evidence": [ { "id": "NP_001074332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.14846.1, SRR13267658.7970.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000011.1. On Aug 10, 2010 this sequence version replaced NP_001074332.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001074332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMTF1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7", "locus": { "chromosome": "1", "start_pos": 8083795, "end_pos": 8112422, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006064", "url": "https://www.ensembl.org/id/ENSGALG00010006064" } ] } } ], "crossref": [ { "id": "A0A1D5NYR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030844", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030844", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418646", "url": "https://www.ncbi.nlm.nih.gov/gene/418646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418646", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQCHTPR", "url": "https://omabrowser.org/oma/group/LQCHTPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYR7", "url": "https://www.orthodb.org/?gene=A0A1D5NYR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46380", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46380", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46380:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46380:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001074332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTVEEESDTVTVETVNSVTLTQDTEGNLILHCPQNETDEVNSEDSTEPPHKRLCLSEDDQSLDDSAPCISVVAVPISENDQSFEVTMTATAEVAEDEINEGTVTQIQILQNEQLDEISPMGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMSNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIERLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELEVSDENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPGHQLSENKSGGGLPNSNSSSGVQHVQIRVARLEENAGNTPGPVTALQIPVQITHVSSTDSPAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTMTLTAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPSVIIRTVAAEDISSSVTQAELTVDSDIQAADLTDPPDALETNSFPDDIHQSKLSDEEHSAYNEDDASKFSSRNSSELMDGVMVRTEEEISDASLKQEEDSHSDLPSTYVTEDLGSPTIEEQVDQPTIDDETVLIVPSSHGFIQTSDDIDSESVLPLTTLTDPILQHHGDGSHIIGSSLGSPDSEDSKDVEDLVSCH", "length": 767, "header": "tr|A0A1D5NYR7-1|A0A1D5NYR7_CHICK Isoform 1 of Cyclin-D-binding Myb-like transcription factor 1 OS=Gallus gallus OX=9031 GN=DMTF1 PE=3 SV=2 CANONICAL=A0A1D5NYR7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7/entry", "sequence": { "sequence": "MSTVEEESDTVTVETVNSVTLTQDTEGNLILHCPQNETDEVNSEDSTEPPHKRLCLSEDDQSLDDSAPCISVVAVPISENDQSFEVTMTATAEVAEDEINEGTVTQIQILQNEQLDEISPMGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMSNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIERLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELEVSDENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPGHQLSENKSGGGLPNSNSSSGVQHVQIRVARLEENAGNTPGPVTALQIPVQITHVSSTDSPAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTMTLTAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPSVIIRTVAAEDISSSVTQAELTVDSDIQAADLTDPPDALETNSFPDDIHQSKLSDEEHSAYNEDDASKFSSRNSSELMDGVMVRTEEEISDASLKQEEDSHSDLPSTYVTEDLGSPTIEEQVDQPTIDDETVLIVPSSHGFIQTSDDIDSESVLPLTTLTDPILQHHGDGSHIIGSSLGSPDSEDSKDVEDLVSCH", "length": 767, "header": "tr|A0A1D5NYR7-1|A0A1D5NYR7_CHICK Isoform 1 of Cyclin-D-binding Myb-like transcription factor 1 OS=Gallus gallus OX=9031 GN=DMTF1 PE=3 SV=2 CANONICAL=A0A1D5NYR7-1" }, "locus": { "chromosome": "1", "start_pos": 8106984, "end_pos": 8085106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014506.1", "url": "https://www.ensembl.org/id/ENSGALT00010014506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008523.1", "url": "https://www.ensembl.org/id/ENSGALP00010008523.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 509, "start_aa": "Thr", "end_pos": 509, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr509", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418646", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SQ26-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTLTRDTDGNLILHCPQNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKPGSGVPNSNSSSSVQHVQIRVARLEDNAAISPSPMTALQIPVQITHVSSADSPAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSVMVRTEEEISDSDLKQEDAPSPLARAYVTEDLESPTIEEQVDQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 762 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BQ00-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTVEEDSDTVTVETVDSVTLTRDTDGNLILHCPHNEADEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEITEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGPGVPNSNSNSSVQHVQIRVARLEDNGAISPSPMTALQIPVQITHVSSADSAAATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLAAAAPASPEQIIVHALSPEHLLNTSDVTVQCHAPRVIIQTVATEDIASSISQAELTVDSDIHSSDFPEPPDALEADTFPDEIHQPKITVEPSFNDAHISKFSDQNSTELMNSIMVRTEEEISVTHLKQEDEPSPLARAYVTEDLGSPTIEEQVHQTTIDDETILIVPSPHGFIQTSDVIDTESVLPLTTLTDPILQHHREESNIIGSSLGSPVSEDSKDVEDLVHCH", "length": 761 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I5J6-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSAEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDIASSVSQAELTVGSDLHSSDFPEPPDALEADTFPDEIPQPKMTIQPSFNTHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPADLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q66HG1-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEMSPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTADSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKYSDQNSTELMNSVMVRTEEEIADTDLKQEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDGIDAESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DG03-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "dmtf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTGDVPATVTLESVNSVTFTQDTDGNIILHCPQNDGEDLGSDETTEPVHKRIRLSSEDGEDPQDSASTEYSVVTLPITDGDESFEVTMTATEMRDEELESDDLSETTGKDSSAQKKGEDVSAVSQAWFTTKEDKDTLVNKGHKWKQGMWSKEEIDLLMTNIELYLKNRGIQDPAEIIFEMSKEERKDFYRSIACGLNRPLFAVYRRVLRMYDNRNHVGKYTDEEINKLKELRQKHGNDWATIGSALGRSASSVKDRCRLMKDTCNTGKWTEEEERRLAEVVHELTGTEAGDVVTQGVSWASVAELVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDDINLVRRIAELEVEDENEINWDILASGWSSVRSPQWLRSKWWTIKRQVANHKELPFPVLLKGLQDVVEAPPSTMNKVVVVGSRSANASPSPVTALQIPVQIPVQITHVSSSDGSSGTSDSETITLNSGALQTFELLPSFHLQPTGTPGTYFLQTGTNQSLPLTLSANPTVTLTAAASPSSPDQIILHSLTTDTENVTVQMSHPGIIIQTVTSEDLADPLGQSELEGEQVLVKEEPSENQTNPAIEEPSEEQSKQGEKTLDSSKVVETVLMVPSPGSFIPTNEDISSDSVLPLGTLTDPILENQEEGSN", "length": 645 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CE22-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "Dmtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEVDSEDSTEPPHKRLCLSSEDDQSIDDATPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTNPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSLSQEELTVDSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEASNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 761 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y222-1", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "gene_name": "DMTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNEADEIDSEDSIEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLEDNTAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH", "length": 760 }, "evidence": [ { "id": "A0A1D5NYR7", "url": "https://omabrowser.org/oma/group/A0A1D5NYR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NYR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 767, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NYR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NYR7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 509 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 644, "end_pos": 646 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NZ00-1", "uniprot_ac": "A0A1D5NZ00", "uniprot_id": "A0A1D5NZ00_CHICK", "mass": { "chemical_mass": 69806.0, "monoisotopic_mass": 69806.0 }, "refseq": { "ac": "XP_001233406", "name": "sec1 family domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406" }, "gene_names": [ { "name": "SCFD2", "type": "recommended", "evidence": [ { "id": "A0A1D5NZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00" } ] }, { "name": "SCFD2", "type": "synonym", "evidence": [ { "id": "XP_001233406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406" } ] } ], "protein_names": [ { "name": "Sec1 family domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A1D5NZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00/entry#names_and_taxonomy" } ] }, { "name": "sec1 family domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001233406.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCFD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00", "locus": { "chromosome": "4", "start_pos": 65461141, "end_pos": 65279736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014267", "url": "https://www.ensembl.org/id/ENSGALG00010014267" } ] } } ], "crossref": [ { "id": "A0A1D5NZ00", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZ00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039168", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770088", "url": "https://www.ncbi.nlm.nih.gov/gene/770088", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770088", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770088", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHEYESL", "url": "https://omabrowser.org/oma/group/FHEYESL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZ00", "url": "https://www.orthodb.org/?gene=A0A1D5NZ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGAVPALPRVCRQAWEPVLARARRAVVFLDAAAAEALHWAAGGAGELLAAGALAVRPLQADGGPAGAERAVFVLSGPLRGGAAAAVRAVLGAGEVRRCALLCGEAEGGAPGELEETLRRWMGEDGRAEVLPRGPPLLAPLSAELGLLPALAGLVPPPSCPRPGGPAEAGLGALPVALRDAVRGLVADLDSLFGAMGLREECFAVGALSRVLAAELAGFAPARNRRRAAANRASVVFVDRTLDLAGAVGHHGDSLAEKILSVLPKLPGHKTDVMVNMVELTALQTPDEACSIIAPGCLAQPNSPAAKALWESFMNLKQKEAVMEARRHLVEAASRENLPIKMSMGRVTPEQLSSYVQLFKNNFKALENHCGLLQLVLAAVQTLKHPQISKWDNFLAFERLLLQTIGESEMPSVLNQLLPMIKSYSERMQDDYTCEDFFILLVYMYSVVGEIRNGEELNKAEEEVKKALVKAICDEPELSPLLQKITGCNSALNLTSQKATDAVDNIFKLLRDIARARTHMKQFNSIHNPGSNTNQASYKPLLKQVVEEICSADRPDSVDIEHMSSGLTDLLKTGFSMFMKVNRSHPGDHPLLIIFMVGGVTVSEVKMVKDLVATRKPSTQVIVLSSTLLTPQGAIEQLFAADHPQLDRDI", "length": 652, "header": "tr|A0A1D5NZ00-1|A0A1D5NZ00_CHICK Isoform 1 of Sec1 family domain containing 2 OS=Gallus gallus OX=9031 GN=SCFD2 PE=1 SV=2 CANONICAL=A0A1D5NZ00-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00/entry", "sequence": { "sequence": "MAAAGAVPALPRVCRQAWEPVLARARRAVVFLDAAAAEALHWAAGGAGELLAAGALAVRPLQADGGPAGAERAVFVLSGPLRGGAAAAVRAVLGAGEVRRCALLCGEAEGGAPGELEETLRRWMGEDGRAEVLPRGPPLLAPLSAELGLLPALAGLVPPPSCPRPGGPAEAGLGALPVALRDAVRGLVADLDSLFGAMGLREECFAVGALSRVLAAELAGFAPARNRRRAAANRASVVFVDRTLDLAGAVGHHGDSLAEKILSVLPKLPGHKTDVMVNMVELTALQTPDEACSIIAPGCLAQPNSPAAKALWESFMNLKQKEAVMEARRHLVEAASRENLPIKMSMGRVTPEQLSSYVQLFKNNFKALENHCGLLQLVLAAVQTLKHPQISKWDNFLAFERLLLQTIGESEMPSVLNQLLPMIKSYSERMQDDYTCEDFFILLVYMYSVVGEIRNGEELNKAEEEVKKALVKAICDEPELSPLLQKITGCNSALNLTSQKATDAVDNIFKLLRDIARARTHMKQFNSIHNPGSNTNQASYKPLLKQVVEEICSADRPDSVDIEHMSSGLTDLLKTGFSMFMKVNRSHPGDHPLLIIFMVGGVTVSEVKMVKDLVATRKPSTQVIVLSSTLLTPQGAIEQLFAADHPQLDRDI", "length": 652, "header": "tr|A0A1D5NZ00-1|A0A1D5NZ00_CHICK Isoform 1 of Sec1 family domain containing 2 OS=Gallus gallus OX=9031 GN=SCFD2 PE=1 SV=2 CANONICAL=A0A1D5NZ00-1" }, "locus": { "chromosome": "4", "start_pos": 65459591, "end_pos": 65279756, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034350.1", "url": "https://www.ensembl.org/id/ENSGALT00010034350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020176.1", "url": "https://www.ensembl.org/id/ENSGALP00010020176.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770088", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770088", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F4IP69-1", "protein_name": "Sec1 family domain-containing protein MIP3", "gene_name": "MIP3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALIDVAISCLNSIREIEEDVKDAIVYIDAGCTESFQFVGAFPLFLELGARAVCSLENMTSLDAVADWNSKSDCAKRIVIMTSRLLNDAHRYMLRCLSTHEGVQRCTVFTSISEGSHSAIPDSPLGPDAYREYETLLVQDYNEHTKKSDKISKDKGVSKFSSALESLTMEPIESENVDISSGGAQGLVVSVHHFPLIICPFTPRAFVLPSQGSVAEASLSRQHEDSLSFGLPPISTGSMSDTDDVPPGATLTAHFLYQLALKMELKLEIFSLGDQSKNVGKILTDMSSVYDVARRKRSAGLLLVDRTLDLITPCCHGDSLFDRIFSSLPRAERFSSQAQLKQGVPSINRPSLDVQVPLGELLNEEPSKIRDSGLPEGIEAFLRGWDSYTSAPQNVGLFNECDKKSTTNWTELLNGSLVATECFRGTPYLEAMIDRKTKDGSVLVKKWLQEALRRENISVNVRARPGYATKPELQAMIKALSQSQSSLLKNKGIIQLGAATAAALDESQSAKWDTFSSAEMMLNVSAGDTSQGLAAQISDLINKSAVAELQAKKNEKPDSSSRGLLSFRDALLLTIVGYILAGENFPTSGSGGPFSWQEEHFLKEAIVDAVLENPSAGNLKFLNGLTEELEGRLNRLKSEETKEIPSDDQLDIDALDDDPWGKWGDEEEEEVDNSKADESYDDMQLKLDLRDRVDSLFRFLHKLSSLRTRNLPLREGSLASESSFPGEPSGNKGLVYRLITKVLSKQEIPGLEYHSSTVGRFIKSGFGRFGLGQAKPSLADQSVILVFVIGGINGIEVLEAQEAVSESGRPDINLVIGGTTLLTPDDMFELLLGQFSHF", "length": 838 }, "evidence": [ { "id": "A0A1D5NZ00", "url": "https://omabrowser.org/oma/group/A0A1D5NZ00/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "I3LLV8-1", "protein_name": "Sec1 family domain containing 2", "gene_name": "SCFD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSIPGVLSFTQQAWEQVLAKVKRAVVYLDAASAESLHWGCGSSRLLEAVGSPACYLREFEPAAVGGGADQPKAVFVLSCLLKGRTVETLRDIICRSHFQYCVVVTAVNHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNMNYTAEVLHIPLLLAPVAPHLALTPAFASLFPLLPQDVHILNGARPDKRRLGSLSEVDATALTPELLLQIRCLVSGLSSLCEHLGVREECFAVGSLSRIIAADLANFAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLVEKIISVLPQLPGHTNDVMVNMVELTALQAEEENQNMVAPGCLAQSNDPAAKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIKMSMGRVTPGQLTSYIQLFKNNLKALGNHCGLLQLGLATIQTLKHPQTAKWDNFLAFERLLLQSIGESTMSVVLNQLMPMIKPSNQRTSDDYSPGELLVLLVYIYSVSGELSVDKDLGEAEEKVKKALAQVFCEESELSPLLQKITGCDSAINLTLPKSKSAVDELFTSLRDIAGARSLMKQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPERPDPVDIEHMSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGVTVSEAKMIKDLVPSLKPGTQVIVLSTRLLKPLLIPELLFATDRLHPDLGF", "length": 684 }, "evidence": [ { "id": "A0A1D5NZ00", "url": "https://omabrowser.org/oma/group/A0A1D5NZ00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54ZW8-1", "protein_name": "Sec1-like family protein", "gene_name": "scfd2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNNNSNNIKLKNNFEKRFQEIENELRDSHIGLDENFYTSINDNIGISKLIRLSKSIYIAKDDDNDENIDKEKETQQHQIFTTQEYENGIEIHDINNRLVFFCSDYLWNCENHIKSLLKIYSINNCIIYCGLSELAHISHPNSSKSKSKSINNLPNFQNFKNKFIEKMKLSFKKENQDINHDGHDDDDDDEYYQDELPDISCTIKYFPLCYSQPFKNFFTIPIQKSLFPSNYFINDLKLNEYKLNKMPEEIQDNVHKSIYSFLSFLNEMKLGSVSGEDLNIYPIGPFSSYLAHEIQTTLATITNQQQDDYHPISLLLIDRTLDLVGPSLHSENSMDRIYFSTTTPLNKSNNNNNNNNNNNNNNNNDQLNNYQPIINIETFFDNDNKIVSESSINECPRIISTINGSDIERHQNLDNTNNNNTSGESSVRLWDSLITKSLKDVIMILKRRLVEIISKENINVDISSIAGPTNIQSLIALVNVLKDGDNNGDYDDSDDNDDDGNDDGDDNGDNHNHMLMYRYNDIIEAVAAVEQTINLSSQFHWDQLLSIEKILLLSSGYELEEEDEDDEDDEDEENEDNSEPSILSQICDIIETPISGGGGDDKYYSIQEILILCVMAYSIKGLTSKLSQKHLNSLSSLNISNSVSNNNSSNSNLSGSGSVNDNNSVSTLEKIPIFSDSDEQRLINCLSDKILKENIYKDLKFLNRESNNNNNNNDNEEKEEEEEEEEEEEDDENIIDKNELNEILKKKVLSKLKSIGIIRQKYLNEHKSLISGGGSSMMGATYSSLLSQLVKSLFENSVSTGGKDIKDFEKFNSSSLVGYLLGKTNWMGRSKKREKPLDNRKVLIYVLGGITFTELKELTDLFEKTLKSSQYKEFSNHQFLIGSNQILTPLKLFNHLFINENKK", "length": 904 }, "evidence": [ { "id": "A0A1D5NZ00", "url": "https://omabrowser.org/oma/group/A0A1D5NZ00/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BTY8-1", "protein_name": "Sec1 family domain-containing protein 2", "gene_name": "Scfd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAAGILAFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACHLREFEPQAIGGGAKQPRAVFVLSSPLKGRIVDTLQSIICRSHFQHCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNENYTAEVLHVPLFLAPVASHLAFTPAFATLFPLLPQDVHALNSARPDKRRLSSLGEVDATALTPELLLYIRCLVSGLSSLCEHLGVREECFAVGPLSRVIATDLANYAPAKNRKKTATGRASVVFVDRTLDLTGAVGHHGDNLVEKIMSVLPQLPGHTHDVMVNMAELTAVQAVEENQNVIAPGCLAPSNEASAKALWEALLNSKHKEAVMEVRRHLVEAASRENLPIKMSMGRVTPGQLMSYIQLFKNNLRALRNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAGVLNQLLPMIKSSSQRTSDDLNPEELLILLIYIYSVPGDVTLDRDLGDVEEKVKKALAHVLSEESELSPLLQKITGCDSAVDLTLPKSQIAVNDVFMALREIAGARNLMRQFKSVYVPGNNTHQASYKPLLKQVVEEIFNPEKSDPIDIEHMSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGVTVAEAKMVKDLVASLKPGTQVMVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 684 }, "evidence": [ { "id": "A0A1D5NZ00", "url": "https://omabrowser.org/oma/group/A0A1D5NZ00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WU76-1", "protein_name": "Sec1 family domain-containing protein 2", "gene_name": "SCFD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSASGVLSFTQQGWEQVLAKVKRAVVYLDAACAESLHWGCGSTRLLEAVGGPDCHLREFEPDAIGGGAKQPKAVFVLSCLLKGRTVEILRDIICRSHFQYCVVVTTVSHAVHLTANHVPAAAAAEMEGQQPVFEQLEEKLCEWMGNMNYTAEVFHVPLLLAPVAPHFALTPAFASLFPLLPQDVHLLNSARPDKRKLGSLGDVDSTTLTPELLLQIRCLVSGLSSLCEHLGVREECFAVGSLSQVIAADLANYAPAKNRKKTAAGRASVVFVDRTLDLTGAVGHHGDNLVEKIISALPQLPGHTNDVMVNMIALTALHTEEENYNVVAPGCLSQSSDTTAKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIKMSMGRVTPGQLMSYIQLFKNNLKALMNHCGLLQLGLATAQTLKHPQTAKWDNFLAFERLLLQSIGESAMSVVLNQLLPMIKPVTQRTNEDYSPEELLILLIYIYSVTGELTVDKDLCEAEEKVKKALAQVFCEESGLSPLLQKITDWDSSINLTFHKSKIAVDELFTSLRDIAGARSLLKQFKSVYVPGNHTHQASYKPLLKQVVEEIFHPERPDSVDIEHMSSGLTDLLKTGFSMFMKVSRPHPSDYPLLILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 684 }, "evidence": [ { "id": "A0A1D5NZ00", "url": "https://omabrowser.org/oma/group/A0A1D5NZ00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NZ00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 652, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NZ00-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZ00" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 495, "end_pos": 497 }, { "start_pos": 584, "end_pos": 586 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NZ72-1", "uniprot_ac": "A0A1D5NZ72", "uniprot_id": "A0A1D5NZ72_CHICK", "mass": { "chemical_mass": 65264.0, "monoisotopic_mass": 65264.0 }, "refseq": { "ac": "NP_001006191", "name": "TRAF-type zinc finger domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191" }, "gene_names": [ { "name": "TRAFD1", "type": "recommended", "evidence": [ { "id": "A0A1D5NZ72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" } ] }, { "name": "TRAFD1", "type": "synonym", "evidence": [ { "id": "NP_001006191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191" } ] } ], "protein_names": [ { "name": "TRAF-type zinc finger domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5NZ72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72/entry#names_and_taxonomy" } ] }, { "name": "TRAF-type zinc finger domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719409.1, SRR13267649.9659.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Mar 18, 2015 this sequence version replaced NP_001006191.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001006191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191" } ] }, { "annotation": "Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZZQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ5#function" }, { "database": "UniProtKB", "id": "ARBA00037636", "url": "https://www.uniprot.org/uniprotkb/ARBA00037636#function" }, { "database": "UniProtKB", "id": "A0A8V1A4X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X8#function" }, { "database": "UniProtKB", "id": "A0A8V1AA12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA12#function" }, { "database": "UniProtKB", "id": "A0A8V1ACA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA3#function" }, { "database": "UniProtKB", "id": "A0A8V1ACB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB3#function" }, { "database": "UniProtKB", "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAFD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72", "locus": { "chromosome": "15", "start_pos": 6333839, "end_pos": 6276480, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025971", "url": "https://www.ensembl.org/id/ENSGALG00010025971" } ] } } ], "crossref": [ { "id": "A0A1D5NZ72", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZ72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043208", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416884", "url": "https://www.ncbi.nlm.nih.gov/gene/416884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416884", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHQSSEC", "url": "https://omabrowser.org/oma/group/AHQSSEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZ72", "url": "https://www.orthodb.org/?gene=A0A1D5NZ72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZZQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4X8", "url": "https://www.orthodb.org/?gene=A0A8V1A4X8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA12", "url": "https://www.orthodb.org/?gene=A0A8V1AA12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACA3", "url": "https://www.orthodb.org/?gene=A0A8V1ACA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACB3", "url": "https://www.orthodb.org/?gene=A0A8V1ACB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16295:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16295:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLKNRGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQTSIRSGRGRNPGTSDVPVGFRSRKVKAKPQSPESGYPEEE", "length": 582, "header": "tr|A0A1D5NZ72-1|A0A1D5NZ72_CHICK Isoform 1 of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=2 CANONICAL=A0A1D5NZ72-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZ72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72/entry", "sequence": { "sequence": "MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLKNRGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQTSIRSGRGRNPGTSDVPVGFRSRKVKAKPQSPESGYPEEE", "length": 582, "header": "tr|A0A1D5NZ72-1|A0A1D5NZ72_CHICK Isoform 1 of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=2 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6317717, "end_pos": 6309464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063340.1", "url": "https://www.ensembl.org/id/ENSGALT00010063340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039100.1", "url": "https://www.ensembl.org/id/ENSGALP00010039100.1" } ] } }, { "isoform_ac": "A0A8V0ZZQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ5/entry", "sequence": { "sequence": "MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLLSIIF", "length": 510, "header": "tr|A0A8V0ZZQ5-1|A0A1D5NZ72_CHICK Computationally mapped isoform of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=1 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6317614, "end_pos": 6309464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063332.1", "url": "https://www.ensembl.org/id/ENSGALT00010063332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039096.1", "url": "https://www.ensembl.org/id/ENSGALP00010039096.1" } ] } }, { "isoform_ac": "A0A8V1A4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X8/entry", "sequence": { "sequence": "MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLKNRGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQTSIRSGRGRNPGTSDVPVGFRSRKVKYKEVQRRKTI", "length": 578, "header": "tr|A0A8V1A4X8-1|A0A1D5NZ72_CHICK Computationally mapped isoform of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=1 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6330770, "end_pos": 6309464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063336.1", "url": "https://www.ensembl.org/id/ENSGALT00010063336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039098.1", "url": "https://www.ensembl.org/id/ENSGALP00010039098.1" } ] } }, { "isoform_ac": "A0A8V1AA12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA12/entry", "sequence": { "sequence": "MEMVWKERYSKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLKNRGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQTSIRSGRGRNPGTSDVPVGFRSRKVKAKPQSPESGYPEEE", "length": 577, "header": "tr|A0A8V1AA12-1|A0A1D5NZ72_CHICK Computationally mapped isoform of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=1 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6317717, "end_pos": 6285545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063345.1", "url": "https://www.ensembl.org/id/ENSGALT00010063345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039104.1", "url": "https://www.ensembl.org/id/ENSGALP00010039104.1" } ] } }, { "isoform_ac": "A0A8V1ACA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACA3/entry", "sequence": { "sequence": "MQFTHCCWTTLLCQAVHFLGPGKGENCTPAVFFLCGREGHKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQV", "length": 350, "header": "tr|A0A8V1ACA3-1|A0A1D5NZ72_CHICK Computationally mapped isoform of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=1 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6314884, "end_pos": 6310061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063328.1", "url": "https://www.ensembl.org/id/ENSGALT00010063328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039092.1", "url": "https://www.ensembl.org/id/ENSGALP00010039092.1" } ] } }, { "isoform_ac": "A0A8V1ACB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB3/entry", "sequence": { "sequence": "MAAVTEVQTQLCGNCKKDIPAANFTIHEIHCSRNLEVCRYCKESVPKSEMKNHIESEHVQVTCKCSMKVEKSLLEDHETSACPLRPAVCQHCDIQLTFNKLQDHESYCGARTEMCSGCGLNIMVKDLKEHPQVCGKEAKRVSKTVPHFEGEDAGLHALRDIRNQLRSDNCAGPLWRMPRVLERQTYSSCVGDRTLKDISRRNVSRTQRNQNQEYGLEQPERNKNINSLYEEQNANLDHMLALSLQNENNPRNNTAAEIHRDVWENRYAKESVPSSCPNETDNSNTLPYDSLLSLNTSNHMKRDEIMLPCEFCEELYPAEDLILHQTGCNPASAFASFSKRGSLDPQKYDDLHNIGYNSCRSDYSSRYQAVQEEGNIIIPCEFCGIQLEEEIVFHHQDQCDLRPATANPADNLPSQQPPSPRDNRERRESPDLARRRIRHQGDVSPGCIEDLRQQRLNCPARGNRALSNAATARNAPLTSSGTVKTSDALNSRGKPRKVAGNEGRLKNRGAGEPASGATPCVRPTQNLHSETFTSSLSRTPVQTSIRSGRGRNPGTSDVPVGFRSRKVKKLVL", "length": 572, "header": "tr|A0A8V1ACB3-1|A0A1D5NZ72_CHICK Computationally mapped isoform of TRAF-type zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TRAFD1 PE=4 SV=1 CANONICAL=A0A1D5NZ72-1" }, "locus": { "chromosome": "15", "start_pos": 6332835, "end_pos": 6309464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063343.1", "url": "https://www.ensembl.org/id/ENSGALT00010063343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039102.1", "url": "https://www.ensembl.org/id/ENSGALP00010039102.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416884", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416884", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJM4-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "TRAFD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEFLDDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGMCAICKEPFPKSDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLRLALCQHCDLELSVLKLKDHEDYCGARTELCGSCGRNVLVKDLKTHPEVCGRNEEEKRDEVTMLPNAYDDSWGQDGIWIASQLRQIEALDPPMRLPRRPLRAFESDLFQSRTTSQRSVTAQFPIQNNLLEEQESQERNRRRQTPKEGGEDSANLDFMLALSLQNEGQPPNMAEQDLWRVVCEADQSHEGPSALNDIRGAADGTMLPCEFCEELYPEELLIDHQTSCNPSCALPPLGVGSTSPKGMEDPDVIFQEIMQQAARNQLDSLGLRSSPPVEDSIIIPCEFCGVQLEEEVLFHHQDQCDQRPATANNHVSEGIPRQDFQPRGTSPELPKRRVRHQGDLSSDYMDDIKQEMAKGPTYPLPLSRPINNMTATSNRLSVSTSGPRPGCQPSPPRTLKLNNLDNQGIRGRNRNSHNGALASEQIPAVHPARSLYPENLVSAFPRGPSGRYGASGRSEGGRNSRVTPTTTSYCSRTVKAKPPKQQGAGDAEEEEEEE", "length": 581 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H282-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "Trafd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEFADDQAARLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDVHMATEHCQVTCKCNKKLEKRQLKQHMETECPLRLAVCQHCDLELSVLKLKEHEDYCGARTELCGSCGRNVLVKELKTHPEVCGRVEEEKKNEAALPPDAYDEPWNQDGIWIASQLLRQIEALDPPMRLPGRPLRAFESDPFHSRPISQRNTTAHFPIQNNLFEEQERQERNRSRQSPKESGENNAHLDFMLALSLQNEGQASSMAEQGFWGSVPEADPAHGGPTSLSDIKGAADETLLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDPGVIFQNFLQQATSNQLDTLVGMSNTAAVEESIIIPCEFCGVQLEEEVLFHHQDQCDQRPATGNHHAMEGIPTQDSQPEDTSPELPKRLVKHQGDPSSGYMDVKQEAAKGSTCSLSPSRTMNNVTTCNPRSECQPSPPRVLKLNNSDSQDRGQSRGSQNGPVASGHAPVIHSIRNIYPENLVPSFPHGPSGRYGASGRSEGGQSSRVTPTAASYHSRAPKAKPPKQQGAGDAEEEEE", "length": 570 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14545-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "TRAFD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPTCKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLRLAVCQHCDLELSILKLKEHEDYCGARTELCGNCGRNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAYDESWGQDGIWIASQLLRQIEALDPPMRLPRRPLRAFESDVFHNRTTNQRNITAQVSIQNNLFEEQERQERNRGQQPPKEGGEESANLDFMLALSLQNEGQASSVAEQDFWRAVCEADQSHGGPRSLSDIKGAADEIMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGVEEPDVIFQNFLQQAASNQLDSLMGLSNSHPVEESIIIPCEFCGVQLEEEVLFHHQDQCDQRPATATNHVTEGIPRLDSQPQETSPELPRRRVRHQGDLSSGYLDDTKQETANGPTSCLPPSRPINNMTATYNQLSRSTSGPRPGCQPSSPCVPKLSNSDSQDIQGRNRDSQNGAIAPGHVSVIRPPQNLYPENIVPSFSPGPSGRYGASGRSEGGRNSRVTPAAANYRSRTAKAKPSKQQGAGDAEEEEEE", "length": 582 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UDK1-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "Trafd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEFRDDQASRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCKCNKKLEKRQLKQHAETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELKTHPEVCGRVEEEKRTEAAIPPEAYDEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLQAFEADPFYSRTTSQRSMAAQFPVQNNLFEEQERQERNRSRQSPKDSAENNAHLDFMLALSLQNEGQATSMVEQGFWESVPEADPARAGPTSLGDIKGAADEILLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDPGTIFQNFLQQATSNQFDTLMGLSSSAAVEDSIIIPCEFCGVQLEEEVLFYHQDQCDQRPATANHRAVEGIPAQDSQPENTSAELSRRRVKHQGDLSSGYMDDVKPESVKGPTYSMSPNRTMNNVASCNRLLNLPSGPRSDCQRSPPGVLKLNNSDSQDIRGQMRGSQNGPIASGHAPVIHSIQNLYPENFAPSFPHGSPGRYGAGGRSEGGRSSRVSPAAAGYHSRAAKAKPPKQQGAGDAEEEEE", "length": 580 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q58D05-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "TRAFD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEFLNDQDTRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKCDMETHMATEHCQVTCKCNKKLEKRQLKKHEETECPLRLALCQHCDLELSVLKLKDHEDYCGARTELCGTCGRNVLVKDLKTHPEVCGRDVEEKRVEAAMPPNAYDESWGPDRIWIASQLRQIEALDPPMRLPRRPLRAFESDLFQSRTTNQRSMTAQFPIQNNLLEEQERQERNRSRQTPKERGEDSANLDFMLALSLQNEGQAPTLAEQDFWRVIYEADQSREGPSALNDIRGAVDETMLPCEFCEELYPEELLIDHQTSCNPSCALPPLSVGSTSPRGVEDPDAIFQKLMRESAGGQFESLMGFSSSAPVEDSVVIPCEFCGVQLEEEVLFHHQDQCDQRPATANNHVSEGIPSQDLQPRETSPELPKRRVRHQGDLSSGYMNDLKQEMAKGPTYPLPSSRPPNNTTAPPNRLSTSTSGPRPGCQPSPPRALKLNNLDSQGVRGHSRNSHNGALAPGHVPAAYPARSLYPENLVPSFPRGPSGRYGASSRSEGGRNPRVTPTAASYRSRTAKAKTPKQQGAGDAEEEEE", "length": 580 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99MM4-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "Trafd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEFPDDQAARLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHVATEHCQVTCKCNKKLEKRQLKQHVETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELQTHPAVCGRVEEEKRSEAAVPPEAYDEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLRAFEADPFYSRTASQRGVTAHFPIQNNLFEEQERQERNRSHQSPKDSAENSAHLDFMLALSLQNEGQASSMVEQGFWESVPEADPARAGPTSLGDIKGAADETLLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDPGAIFQNFLQQATSNQLDTLMGLSSSAAVEDSIIIPCEFCGVQLEEEVLFHHQDQCDQRPATANHRAMEGIPTQDSQPEDRSPELSRRRVKHQGDLSSGYMDDVKQESVKGSTYSLSPNRTMNNVSTCNRLLNSSGPRSDCQRSPPGVLKLNNSGSQDIRGRIRGSQNGPIASAHAPVIHSIRNLYPENLAPSFPHGSPGRFGASEGSRSSRVTPTAASYHSRAAKAKPPKQQGAGDAEEEEE", "length": 576 }, "evidence": [ { "id": "A0A1D5NZ72", "url": "https://omabrowser.org/oma/group/A0A1D5NZ72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZ72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NZ72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 582, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NZ72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZ72" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NZ72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZ72" }, { "id": "PF21366", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAFD1/XAF1 zinc finger", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 135, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000341.1. On Dec 5, 2015 this sequence version replaced XP_417891.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V1A734", "url": "https://www.orthodb.org/?gene=A0A8V1A734", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31898", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31898", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31898:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31898:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001304665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304665", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZD1-1", "url": 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Transmembrane protein 136 family member 1 OS=Gallus gallus OX=9031 GN=TMEM136-1 PE=4 SV=1 CANONICAL=A0A1D5NZD1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZD1/entry", "sequence": { "sequence": "MLPIALEVLGSLLAWLCLYAAFCLWNRHRSPEWNCRLVTLLHGATATCLSGYIALWDGPWPLSHAGSPNTALQVHVLSLTLGYFIFDLLWCLYFQTEGDLMLLHHTLSICGMVLVLGLGKSATEVNAVVFVSEITNPLLQTRWFLREMGCYHSFLGEVVDFCFVLLFLVLRIGGGALIMYAMVTAPDPNWILKGGGLAMYIVSLGFMVEICRFVRRKMLKKYHSWRRLRSEDAPVKTNGHLAAH", "length": 244, "header": "tr|A0A1D5NZD1-1|A0A1D5NZD1_CHICK Isoform 1 of Transmembrane protein 136 family member 1 OS=Gallus gallus OX=9031 GN=TMEM136-1 PE=4 SV=1 CANONICAL=A0A1D5NZD1-1" }, "locus": { "chromosome": "24", "start_pos": 3846842, "end_pos": 3845557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063239.1", "url": "https://www.ensembl.org/id/ENSGALT00010063239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039041.1", "url": "https://www.ensembl.org/id/ENSGALP00010039041.1" } ] } }, { "isoform_ac": "A0A8V1A4R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4R1/entry", "sequence": { "sequence": "MCVFWGHGKAPSSSPLLPQHLLPLVVLPRHLLRVLRLNFIALLLSGSPNTALQVHVLSLTLGYFIFDLLWCLYFQTEGDLMLLHHTLSICGMVLVLGLGKSATEVNAVVFVSEITNPLLQTRWFLREMGCYHSFLGEVVDFCFVLLFLVLRIGGGALIMYAMVTAPDPNWILKGGGLAMYIVSLGFMVEICRFVRRKMLKKYHSWRRLRSEDAPVKTNGHLAAH", "length": 224, "header": "tr|A0A8V1A4R1-1|A0A1D5NZD1_CHICK Computationally mapped isoform of Transmembrane protein 136 family member 1 OS=Gallus gallus OX=9031 GN=TMEM136-1 PE=4 SV=1 CANONICAL=A0A1D5NZD1-1" }, "locus": { "chromosome": "24", "start_pos": 3846565, "end_pos": 3845557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063234.1", "url": "https://www.ensembl.org/id/ENSGALT00010063234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039036.1", "url": "https://www.ensembl.org/id/ENSGALP00010039036.1" } ] } }, { "isoform_ac": "A0A8V1A734-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A734/entry", "sequence": { "sequence": "MLLHHTLSICGMVLVLGLGKSATEVNAVVFVSEITNPLLQTRWFLREMGCYHSFLGEVVDFCFVLLFLVLRIGGGALIMYAMVTAPDPNWILKGGGLAMYIVSLGFMVEICRFVRRKMLKKYHSWRRLRSEDAPVKTNGHLAAH", "length": 144, "header": "tr|A0A8V1A734-1|A0A1D5NZD1_CHICK Computationally mapped isoform of Transmembrane protein 136 family member 1 OS=Gallus gallus OX=9031 GN=TMEM136-1 PE=4 SV=1 CANONICAL=A0A1D5NZD1-1" }, "locus": { "chromosome": "24", "start_pos": 3845988, "end_pos": 3845557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063242.1", "url": "https://www.ensembl.org/id/ENSGALT00010063242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039044.1", "url": "https://www.ensembl.org/id/ENSGALP00010039044.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419753", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419753", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NZD1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NZD1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZD1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NZH5-1", "uniprot_ac": "A0A1D5NZH5", "uniprot_id": "A0A1D5NZH5_CHICK", "mass": { "chemical_mass": 88186.0, "monoisotopic_mass": 88186.0 }, "refseq": { "ac": "XP_015144419", "name": "FHF complex subunit HOOK interacting protein 2A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419" }, "gene_names": [ { "name": "FHIP2A", "type": "recommended", "evidence": [ { "id": "A0A1D5NZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5" } ] }, { "name": "FHIP2A", "type": "synonym", "evidence": [ { "id": "XP_015144419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK interacting protein 2A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015144419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419" } ] }, { "name": "FHF complex subunit HOOK interacting protein 2A", "type": "synonym", "evidence": [ { "id": "A0A1D5NZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZH5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FHIP2A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5", "locus": { "chromosome": "6", "start_pos": 28821673, "end_pos": 28790490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022494", "url": "https://www.ensembl.org/id/ENSGALG00010022494" } ] } } ], "crossref": [ { "id": "A0A1D5NZH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031404", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031404", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423912", "url": "https://www.ncbi.nlm.nih.gov/gene/423912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423912", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NZH5", "url": "https://www.orthodb.org/?gene=A0A1D5NZH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZID6", "url": "https://www.orthodb.org/?gene=A0A8V0ZID6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZNQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR65", "url": "https://www.orthodb.org/?gene=A0A8V0ZR65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW62", "url": "https://www.orthodb.org/?gene=A0A8V0ZW62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144419", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZH5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZID6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLEVIQDPVLHLCRRQSKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLFPHPHIHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 777, "header": "tr|A0A1D5NZH5-1|A0A1D5NZH5_CHICK Isoform 1 of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5/entry", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLEVIQDPVLHLCRRQSKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLFPHPHIHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 777, "header": "tr|A0A1D5NZH5-1|A0A1D5NZH5_CHICK Isoform 1 of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28820706, "end_pos": 28790706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054766.1", "url": "https://www.ensembl.org/id/ENSGALT00010054766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033100.1", "url": "https://www.ensembl.org/id/ENSGALP00010033100.1" } ] } }, { "isoform_ac": "A0A8V0ZID6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID6/entry", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLESKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 717, "header": "tr|A0A8V0ZID6-1|A0A8V0ZID6_CHICK Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28820706, "end_pos": 28790706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054757.1", "url": "https://www.ensembl.org/id/ENSGALT00010054757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033093.1", "url": "https://www.ensembl.org/id/ENSGALP00010033093.1" } ] } }, { "isoform_ac": "A0A8V0ZNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ2/entry", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADVDTSEENTHFGACRMFQ", "length": 115, "header": "tr|A0A8V0ZNQ2-1|A0A8V0ZNQ2_CHICK Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=4 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28800900, "end_pos": 28790706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054738.1", "url": "https://www.ensembl.org/id/ENSGALT00010054738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033080.1", "url": "https://www.ensembl.org/id/ENSGALP00010033080.1" } ] } }, { "isoform_ac": "A0A8V0ZQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH7/entry", "sequence": { "sequence": "MYELAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLESKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLFPHPHIHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 752, "header": "tr|A0A8V0ZQH7-1|A0A8V0ZQH7_CHICK Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28820706, "end_pos": 28795007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054741.1", "url": "https://www.ensembl.org/id/ENSGALT00010054741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033082.1", "url": "https://www.ensembl.org/id/ENSGALP00010033082.1" } ] } }, { "isoform_ac": "A0A8V0ZR65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR65/entry", "sequence": { "sequence": "MFLLYGLAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLESKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLFPHPHIHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 755, "header": "tr|A0A8V0ZR65-1|A0A8V0ZR65_CHICK Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28820706, "end_pos": 28793193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054746.1", "url": "https://www.ensembl.org/id/ENSGALT00010054746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033086.1", "url": "https://www.ensembl.org/id/ENSGALP00010033086.1" } ] } }, { "isoform_ac": "A0A8V0ZW62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW62/entry", "sequence": { "sequence": "MAEKRRAYMANHIPCQLAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLAFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLESKLKAMASKESTNVITEDMLKGQDSLATDTGQAIQPEEMPGAAGAEHMEKEDELPQQADDLSFSLDELNVTSSPESSTVCPNQDYNLVNSLLNLTKSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLATLYRALPQSLDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKIAAVAMAKAVRERFFVDVMEPQLMQTSEIGILTSTALLHRIVRQVTSDVLLQELVYFVLGEHREPETLPNINRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPHEHILYNLVLRNLEERNYIEYKPLCQEDKDVVENGQIAGAIDLEEDPLFTDLSPDNTGAQEWLSVSPPVSPEHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCLICLRWEWPGSPRSLEKCNLEASFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLFPHPHIHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIPDFTPKLLLVRKRLLGLEPEGPVIDHMTLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 765, "header": "tr|A0A8V0ZW62-1|A0A1D5NZH5_CHICK Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A OS=Gallus gallus OX=9031 GN=FHIP2A PE=1 SV=1 CANONICAL=A0A1D5NZH5-1" }, "locus": { "chromosome": "6", "start_pos": 28820706, "end_pos": 28791657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054752.1", "url": "https://www.ensembl.org/id/ENSGALT00010054752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033089.1", "url": "https://www.ensembl.org/id/ENSGALP00010033089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423912", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NZH5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 777, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NZH5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZH5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZH5" }, { "id": "PF19314", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHF complex subunit HOOK-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 644, "end_pos": 736, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5NZJ2-1", "uniprot_ac": "A0A1D5NZJ2", "uniprot_id": "A0A1D5NZJ2_CHICK", "mass": { "chemical_mass": 44487.0, "monoisotopic_mass": 44487.0 }, "refseq": { "ac": "NP_001292186", "name": "periphilin-1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186" }, "gene_names": [ { "name": "PPHLN1", "type": "recommended", "evidence": [ { "id": "A0A1D5NZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ] }, { "name": "PPHLN1", "type": "synonym", "evidence": [ { "id": "NP_001292186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186" } ] }, { "name": "periphilin-1", "type": "synonym", "evidence": [ { "id": "NP_001292186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186" } ] } ], "protein_names": [ { "name": "Periphilin 1", "type": "synonym", "evidence": [ { "id": "A0A1D5NZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2/entry#names_and_taxonomy" } ] }, { "name": "periphilin-1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001292186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.148687.1, SRR13267658.53.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript data from different strains and from genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPHLN1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2", "locus": { "chromosome": "1", "start_pos": 29789930, "end_pos": 29719821, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001838", "url": "https://www.ensembl.org/id/ENSGALG00010001838" } ] } } ], "crossref": [ { "id": "A0A1D5NZJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009547", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417792", "url": "https://www.ncbi.nlm.nih.gov/gene/417792", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HVEYRDY", "url": "https://omabrowser.org/oma/group/HVEYRDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZJ2", "url": "https://www.orthodb.org/?gene=A0A1D5NZJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15836", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15836", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15836:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15836:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9843970", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYRRDEMWSEGRYDYERLPRERLPPRIHPDDDYHRVVNVMPKKPPLLDRPGEGSYSRYDDYSHTEYRDYEEGRSFAHERRSGPPHRGVHKDESGYRWPRDDHPMNRQTEYRKVRDGFRRKSFHPSHYMRERSPHKRDSPFFRESPVSRRDSPHSRSGSSVSSRSYSPERSKAYPFHQSQHSRSMSSLHKRNISSQQGKERTSVQSSKTSRDASPSGSTAVPSTKTVEKSNRLSEKELAEAASKWAAEKLEKADENNLPERTEYEAGSSAPLYVEQTEETETNVTDSTELYEDNQLLCRSKAIATKTKEIEQVYRQDCETFGMVVKMLIDKDPSLEKSIQFALRQNLHEIGERCIEELKHFIAEYDAANQDISESFKDGSY", "length": 381, "header": "tr|A0A1D5NZJ2-1|A0A1D5NZJ2_CHICK Isoform 1 of Periphilin 1 OS=Gallus gallus OX=9031 GN=PPHLN1 PE=4 SV=1 CANONICAL=A0A1D5NZJ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2/entry", "sequence": { "sequence": "MAYRRDEMWSEGRYDYERLPRERLPPRIHPDDDYHRVVNVMPKKPPLLDRPGEGSYSRYDDYSHTEYRDYEEGRSFAHERRSGPPHRGVHKDESGYRWPRDDHPMNRQTEYRKVRDGFRRKSFHPSHYMRERSPHKRDSPFFRESPVSRRDSPHSRSGSSVSSRSYSPERSKAYPFHQSQHSRSMSSLHKRNISSQQGKERTSVQSSKTSRDASPSGSTAVPSTKTVEKSNRLSEKELAEAASKWAAEKLEKADENNLPERTEYEAGSSAPLYVEQTEETETNVTDSTELYEDNQLLCRSKAIATKTKEIEQVYRQDCETFGMVVKMLIDKDPSLEKSIQFALRQNLHEIGERCIEELKHFIAEYDAANQDISESFKDGSY", "length": 381, "header": "tr|A0A1D5NZJ2-1|A0A1D5NZJ2_CHICK Isoform 1 of Periphilin 1 OS=Gallus gallus OX=9031 GN=PPHLN1 PE=4 SV=1 CANONICAL=A0A1D5NZJ2-1" }, "locus": { "chromosome": "1", "start_pos": 29787811, "end_pos": 29724978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004186.1", "url": "https://www.ensembl.org/id/ENSGALT00010004186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002483.1", "url": "https://www.ensembl.org/id/ENSGALP00010002483.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MVX9-1", "protein_name": "Periphilin 1", "gene_name": "PPHLN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAYRGNEMCSEGRYDYERLPRERVSPRSHASDGYRRVVNVVPKKPPLLDRPGEGSYNRYYSHVDYRDCDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDNFRRKSFNSYYVRERSPHKRNTPFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKTYSFHQSQHRKSVRAGACYKRQNEGRPERGKERPVQPLKTSRDTSPSSSSAVASSKVLDKPSRLTEKELAEAASKWAAEKLEKADESNLPEISEYEAGSTAPLFIDHPVEPESNATDGIELFEDSQLTSRSKAIATKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSSQDFGEPF", "length": 373 }, "evidence": [ { "id": "A0A1D5NZJ2", "url": "https://omabrowser.org/oma/group/A0A1D5NZJ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6A7X8-1", "protein_name": "Periphilin 1", "gene_name": "Pphln1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTRAGCSRDPGRGWGRGRGRGRGRGRGRGSLRAPAPWELTFDAVAEQAGCEPAAAPPPAAFRGAQERGRPRPQRGAAFLPYPRNPGAPGPEAGAPGDVTTRAGSAFGASGRLASRVSPAAAAAAAARQWNVVASTRDEMWSEGRYDYERLPRERVPPRSHPSDEFGYRWTRDDHSTSRQSDYRDMRDGFRRKSFYSSHYSRDRSPHKRDAPFFRESPVGRKDSPHSRSGSSVSSRSYSPERSRTHTFHQSQHRKSSRVGASYKRQNEATRGRGKERSIQSLKTSRDTSPSSSSAVSSSKALDKPSRLTEKELAEAESKWAADTLERSDENNLGEISEFEAGSAAPLFIDQTEEPESNTTDGTEMYEDSQLSSRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFITEYDNSTQDFGDPF", "length": 451 }, "evidence": [ { "id": "A0A1D5NZJ2", "url": "https://omabrowser.org/oma/group/A0A1D5NZJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2H1-1", "protein_name": "Periphilin-1", "gene_name": "Pphln1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWSEGRYDYDRLPRERVPPRSHPSDGYHRVVNVVPKRPPLLDKRPPLLDKRPPLLARPDEGGYSRYYSHVDCRVCDEGRSFSHDRRSGPSHSGDESGYRWLRDDHSTSRQPDYRDMRDGFRRKSFYSSHYSRDRSPHKRDAPFFRESPVGRKDSPHSRSGSSVSSRSYSPERSRTHSFHQSQHRKSSRVGASYKRQNEAIRGRGKERSIQSVKTSRDASPSSSSAVASSKALDKPSRLTEKELAEAESKWANETLEKSDESNLAEMNEFEAGSTAPLFIDQTEEPESNTVDGTELYEDSQLSNRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSVQFALRQNLHEIGERCVEELKRFITEYDNSARDFGDPF", "length": 381 }, "evidence": [ { "id": "A0A1D5NZJ2", "url": "https://omabrowser.org/oma/group/A0A1D5NZJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEY8-1", "protein_name": "Periphilin-1", "gene_name": "PPHLN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ", "length": 458 }, "evidence": [ { "id": "A0A1D5NZJ2", "url": "https://omabrowser.org/oma/group/A0A1D5NZJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "HUSH2 complex", "id": "GO:0140286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140286", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "HUSH complex", "id": "GO:0140283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "protein localization to heterochromatin", "id": "GO:0097355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" }, { "name": "transposable element silencing by heterochromatin formation", "id": "GO:0141005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NZJ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5NZJ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 381, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5NZJ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5NZJ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5NZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZJ2" }, { "id": "PF25234", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Periphilin-1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 367, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P017-1", "uniprot_ac": "A0A1D5P017", "uniprot_id": "A0A1D5P017_CHICK", "mass": { "chemical_mass": 61701.0, "monoisotopic_mass": 61701.0 }, "refseq": { "ac": "XP_025010029", "name": "coiled-coil domain-containing protein 102A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010029" }, "gene_names": [ { "name": "CCDC102A", "type": "recommended", "evidence": [ { "id": "A0A1D5P017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017" } ] }, { "name": "CCDC102A", "type": "synonym", "evidence": [ { "id": "XP_025010029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010029" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 102A", "type": "recommended", "evidence": [ { "id": "A0A1D5P017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 102A", "type": "synonym", "evidence": [ { "id": "XP_025010029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010029" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010029" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P017", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC102A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017", "locus": { "chromosome": "11", "start_pos": 540422, "end_pos": 534079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024498", "url": "https://www.ensembl.org/id/ENSGALG00010024498" } ] } } ], "crossref": [ { "id": "A0A1D5P017", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P017", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029999", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029999", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427528", "url": "https://www.ncbi.nlm.nih.gov/gene/427528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EELEGCW", "url": "https://omabrowser.org/oma/group/EELEGCW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P017", "url": "https://www.orthodb.org/?gene=A0A1D5P017", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46292:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46292:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P017", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P017-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSGAPRLAGSPQLHGGSLLALLGPERGGGSEPGPTPSPPSPPSGTPSPGPPPALLEADWEGREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRHRLEALTKELAGLRRERQEGLQERQQLGRQLARLRGHEGGTDGDGDDGDGEAAPESEPVRDVGAEAPPKAKELELMENILKGKQEGSDSWEQRSAAGTRSSFSRQERSRLLWEDVSVVEEDASKITALKLRLDESQKVLLKEREDKLALSKSIEKLEGELSQWKIKYEELNKNKQEVMKQLNILKEIHQDELGRISEDLEDELGARSSMDKKLAELRMEMERLQAENAAEWGRRERLETEKLNLERENKKLRAQIEDLEEVLARKRRQTASALDTDLKTIQAELFEKNKELADLKHVHAKLKKQYQEKTAELAHANRRVEQHEGEVKKLRLRVEELKKELAQAEDELDEAHNQTRKLQRSLDEQTEQSESFQVQLEHLQSRLRRQQSTPLFGKMRSARFGPDDPGDGTSDPDEDEDLQIQVP", "length": 540, "header": "tr|A0A1D5P017-1|A0A1D5P017_CHICK Isoform 1 of Coiled-coil domain-containing protein 102A OS=Gallus gallus OX=9031 GN=CCDC102A PE=1 SV=3 CANONICAL=A0A1D5P017-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P017-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017/entry", "sequence": { "sequence": "MSQSGAPRLAGSPQLHGGSLLALLGPERGGGSEPGPTPSPPSPPSGTPSPGPPPALLEADWEGREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRHRLEALTKELAGLRRERQEGLQERQQLGRQLARLRGHEGGTDGDGDDGDGEAAPESEPVRDVGAEAPPKAKELELMENILKGKQEGSDSWEQRSAAGTRSSFSRQERSRLLWEDVSVVEEDASKITALKLRLDESQKVLLKEREDKLALSKSIEKLEGELSQWKIKYEELNKNKQEVMKQLNILKEIHQDELGRISEDLEDELGARSSMDKKLAELRMEMERLQAENAAEWGRRERLETEKLNLERENKKLRAQIEDLEEVLARKRRQTASALDTDLKTIQAELFEKNKELADLKHVHAKLKKQYQEKTAELAHANRRVEQHEGEVKKLRLRVEELKKELAQAEDELDEAHNQTRKLQRSLDEQTEQSESFQVQLEHLQSRLRRQQSTPLFGKMRSARFGPDDPGDGTSDPDEDEDLQIQVP", "length": 540, "header": "tr|A0A1D5P017-1|A0A1D5P017_CHICK Isoform 1 of Coiled-coil domain-containing protein 102A OS=Gallus gallus OX=9031 GN=CCDC102A PE=1 SV=3 CANONICAL=A0A1D5P017-1" }, "locus": { "chromosome": "11", "start_pos": 540017, "end_pos": 535936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059746.1", "url": "https://www.ensembl.org/id/ENSGALT00010059746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036506.1", "url": "https://www.ensembl.org/id/ENSGALP00010036506.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZSR7-1", "protein_name": "Coiled-coil domain-containing protein 102A", "gene_name": "Ccdc102a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPTLPLTAPALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLRGARGAADKTQEGPEAEREHEPVRDIGAERSPGSQELDLVESLLKSRPEELEGCWDACSVAAGGSRVSSGRQDRNRLPWEDTAGTEEDTSKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHSKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSTRFGTEEAGDGASDLDEDEDLQIQVA", "length": 549 }, "evidence": [ { "id": "A0A1D5P017", "url": "https://omabrowser.org/oma/group/A0A1D5P017/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LHY5-1", "protein_name": "Coiled-coil domain-containing protein 102A", "gene_name": "CCDC102A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHGPSPRLAESPQLSKGSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPSLPLPPAPTLLADGDWESREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLRGAGGPTDRTPEGPETEPEREQEPVRDVGSERPQGSQELELVESLLKSRPEEPEGCWEARSVGAGAPRSSSGRQERSRLPWEDAATLEEDTSKLTALRLRLDESQKVLLKEREDKMALSRNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQLGDLEEALARRRRQTASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHVQSRLRRQQQSAPLFGKIRSARFGAEEAGDGASDLDEDEDLQIQVA", "length": 552 }, "evidence": [ { "id": "A0A1D5P017", "url": "https://omabrowser.org/oma/group/A0A1D5P017/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3TMW1-1", "protein_name": "Coiled-coil domain-containing protein 102A", "gene_name": "Ccdc102a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPSLPLTAPALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLRGVHSAADKTHDGPEPEREQEPVRDIGAERPPGSQELDLVESLLKSRPEEPEGCWDACSVAAGGPRVSSGRQDRNRLPWEDTASTEEDASKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSTRFGTEEAGDGASDLDEDEDLQIQVA", "length": 549 }, "evidence": [ { "id": "A0A1D5P017", "url": "https://omabrowser.org/oma/group/A0A1D5P017/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96A19-1", "protein_name": "Coiled-coil domain-containing protein 102A", "gene_name": "CCDC102A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHGPSPRLAESPQLSKGSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPALPLPPAPALLADGDWESREELRLRELEEARARAAQMEKTMRRWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLRGARGVADQTRDGPEPEAEREPVRDVGSERPPGSQELELVESLLKSMPEESEDCWEARSLGAGGPRGSSGRQERSRLPWEDTAATEEEASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSARFGTEEAEDGTSDLDEDEDLQIQVA", "length": 550 }, "evidence": [ { "id": "A0A1D5P017", "url": "https://omabrowser.org/oma/group/A0A1D5P017/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P017", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P017-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 540, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P017-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P017" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P017" }, { "id": "PF01576", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin tail", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 500, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37, 47 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P057-1", "uniprot_ac": "A0A1D5P057", "uniprot_id": "A0A1D5P057_CHICK", "mass": { "chemical_mass": 71771.0, "monoisotopic_mass": 71771.0 }, "refseq": { "ac": "XP_015139871", "name": "piggyBac transposable element-derived protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139871" }, "gene_names": [ { "name": "PGBD5", "type": "recommended", "evidence": [ { "id": "A0A1D5P057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ] }, { "name": "PGBD5", "type": "synonym", "evidence": [ { "id": "XP_015139871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139871" } ] } ], "protein_names": [ { "name": "PiggyBac transposable element derived 5", "type": "synonym", "evidence": [ { "id": "A0A1D5P057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057/entry#names_and_taxonomy" } ] }, { "name": "piggyBac transposable element-derived protein 5", "type": "synonym", "evidence": [ { "id": "XP_015139871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139871" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015139871.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139871" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGBD5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057", "locus": { "chromosome": "3", "start_pos": 39993290, "end_pos": 40057700, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006966", "url": "https://www.ensembl.org/id/ENSGALG00010006966" } ] } } ], "crossref": [ { "id": "A0A1D5P057", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P057", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011111", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011111", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421541", "url": "https://www.ncbi.nlm.nih.gov/gene/421541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421541", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421541", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMTQSRF", "url": "https://omabrowser.org/oma/group/IMTQSRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P057", "url": "https://www.orthodb.org/?gene=A0A1D5P057", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28576", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28576", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28576:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28576:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P057-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWYLEMLSWLLPPMSLHTHRGGWCGREREAGLSPGGGGAHPSACLPAAVPEPLLLLGCCLRPQDPAEPARGERGRLLAAAEMMAEGGGGPARRKALSLLEAARSRYESLQISDDVFGESGQDSSGNPFYSTSADSRSAASSQDEEDDDEGEGRPEGPCPRSRAARRRVPRPAPATAERRRQQQRQTGGGGAMPGGPGPMEEGEEEDAETGGWTRSLRDVPPPRFKDSSGPTRKMPLTASAMDFFQLFVPDNVLKNMVVQTNMYAKKYQERFGSDDTWIDVTLTEMKAFLGYMISTSIHHCESVLSIWSSGFYSNKSIALIMTQSRFEKILKYFHIVAFRSSQTTHGLYKIQPFLDSLQNGFDSAFRPSQAQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFICQIYVHLKEGSGADGLDALKNKPQLHSMVAKSLCQNASGKNYIIFTGPSITSLNLFEEFEKQEIYCCGLLSARKSDCTGLPPSMLNNPDTPQSRGQYRIRMKGNMSLICWYNKGHFRFLTNAYSPVQQGVIIKRKSGEIPCPLAVEAFAAHLSYICKYDDKYSKYFISHKPNKTWQQVFWFAISIAINNAYILYKMSEAYHVTRYSRAQFGERLVKELLGLEDTSPSH", "length": 642, "header": "tr|A0A1D5P057-1|A0A1D5P057_CHICK Isoform 1 of PiggyBac transposable element derived 5 OS=Gallus gallus OX=9031 GN=PGBD5 PE=4 SV=1 CANONICAL=A0A1D5P057-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P057-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057/entry", "sequence": { "sequence": "MWYLEMLSWLLPPMSLHTHRGGWCGREREAGLSPGGGGAHPSACLPAAVPEPLLLLGCCLRPQDPAEPARGERGRLLAAAEMMAEGGGGPARRKALSLLEAARSRYESLQISDDVFGESGQDSSGNPFYSTSADSRSAASSQDEEDDDEGEGRPEGPCPRSRAARRRVPRPAPATAERRRQQQRQTGGGGAMPGGPGPMEEGEEEDAETGGWTRSLRDVPPPRFKDSSGPTRKMPLTASAMDFFQLFVPDNVLKNMVVQTNMYAKKYQERFGSDDTWIDVTLTEMKAFLGYMISTSIHHCESVLSIWSSGFYSNKSIALIMTQSRFEKILKYFHIVAFRSSQTTHGLYKIQPFLDSLQNGFDSAFRPSQAQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFICQIYVHLKEGSGADGLDALKNKPQLHSMVAKSLCQNASGKNYIIFTGPSITSLNLFEEFEKQEIYCCGLLSARKSDCTGLPPSMLNNPDTPQSRGQYRIRMKGNMSLICWYNKGHFRFLTNAYSPVQQGVIIKRKSGEIPCPLAVEAFAAHLSYICKYDDKYSKYFISHKPNKTWQQVFWFAISIAINNAYILYKMSEAYHVTRYSRAQFGERLVKELLGLEDTSPSH", "length": 642, "header": "tr|A0A1D5P057-1|A0A1D5P057_CHICK Isoform 1 of PiggyBac transposable element derived 5 OS=Gallus gallus OX=9031 GN=PGBD5 PE=4 SV=1 CANONICAL=A0A1D5P057-1" }, "locus": { "chromosome": "3", "start_pos": 40057694, "end_pos": 39993604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016536.1", "url": "https://www.ensembl.org/id/ENSGALT00010016536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009380.1", "url": "https://www.ensembl.org/id/ENSGALP00010009380.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421541", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BDC3-1", "protein_name": "PiggyBac transposable element derived 5", "gene_name": "PGBD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEGGGGARKRAPALLEAARARYESLHISDDVFGESGPDSGGNPFYSTSAASHSSSAASSDDEPERPGPAAPPPGAPDAPDLEEDEAGAGWSATLRDRPPPRFEDTGGPTRKMPPSASAMDFFQLFVPDNVLKNMVVQTNMYARKFQERFGSDGAWVDVTLPEMKAFLGYVISTSTSHCESVLSIWSGGFYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQPFLDSLQTSFDSAFRPSQTQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFIIQIYVHLKEGSGPDGLDALKNKPQLHGMVAKNLCRNAAGKNYIIFTGPSITSLTLFEEFEKQEIYCCGLLSSRKSDCTGLPPSMLSNPATPPARGQHQIRMKGSMSLICWYNKGHFRFLTNAYSPMQQGVIIKRRSGEIPCPLAVEAFAAHLSYICKYDDKYSKYFISHKPNKTWQQVFWFAISIAINNAYILYKMSDAYHVKRYSRAQFGERLVRELLGLEDASPAH", "length": 521 }, "evidence": [ { "id": "A0A1D5P057", "url": "https://omabrowser.org/oma/group/A0A1D5P057/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3YZI9-1", "protein_name": "PiggyBac transposable element-derived protein 5", "gene_name": "Pgbd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGGGGSRRRAPALLEAARARYESLHISDDVFGESGPDSGGNPFYSTSAASRSSSAASSDDERERPAPPGTAPPSYAADPLELEEDETGGGWSAVLRDRPSPRFEDTGGPTRKMPPSASAVDFFQLFVPDNVLKNMVVQTNMYARKFQERFGSDGAWVEVTLAEMKAFLGYVISTSVSHCESVLSIWSGGFYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQPFLDSLQSGFDAAFRPSQTQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFIIQIYVHLKEGGGPDGLDALKNKPQLHSMVARSLCRNAAGKNYIIFTGPSITSLNLFEEFEKQGIYCCGLLSSRKSDCTGLPPSMLTNPATPLARGQHQIRTKGNMSLICWYNKGHFRFLTNAYSPVQKGVIIKRRSGEIPCPLAVEAFAAHLSYICRYDDKYSKYFISHKPNKTWQQVFWFAISIAVNNAYILYKMSDAYHVKKYSRAQFGERLVRELLGLEDSSPAH", "length": 523 }, "evidence": [ { "id": "A0A1D5P057", "url": "https://omabrowser.org/oma/group/A0A1D5P057/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZSZ4-1", "protein_name": "PiggyBac transposable element derived 5", "gene_name": "Pgbd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGGGGARKRAPALLEAARARYESLHISDDVFGESGPDSGGNPFYSTSAASRSSSAASSDDERERPAPPGTAPPPHAADPLELEEDETGGGWSTVLRDRPPPRFEDTGGPTRKMPPSASAVDFFQLFVPDNVLKNMVVQTNMYARKFQERFGSDGAWVEVTLAEMKAFLGYVISTSVSHCESVLSIWSGGFYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQPFLDSLQSGFDAAFRPSQTQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFIIQIYVHLKEGGGPDGLDALKNKPQLHSMVARSLCRNAAGKNYIIFTGPSITSLTLFEEFEKQGIYCCGLLSSRKSDCTGLPPSMLTNPATPLARGQHQIRTKGNMSLICWYNKGHFRFLTNAYSPVQQGVIIKRRSGEIPCPLAVEAFAAHLSYICRYDDKYSKYFISHKPNKTWQQVFWFAISIAVNNAYILYKMSDAYHVKRYSRAQFGERLVRELLGLEDESPAH", "length": 523 }, "evidence": [ { "id": "A0A1D5P057", "url": "https://omabrowser.org/oma/group/A0A1D5P057/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZM83-1", "protein_name": "PiggyBac transposable element-derived protein 5", "gene_name": "pgbd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAECGRRGLSLLEEARSRYESLQISDDVFGESGDDSSENPFYSTTGDSNSDNYPETNADDARVNETRSQSCVPPGSVSSGQAQEEGWGDTLRDLSLPHYQDTHGPTQKMSATATAMDFFQLFVPDNVIQNMVTQTNMYAKKFQERFGSDEGWTNVTLAEMKAFLGYVTSTSVNRCESVLSIWSSGFFSNRSIALKMSQARFEKILKYFHVVAFRSSQGGSQGLYKIQPFLDSLQQSFSSSFRPSQTQVLHEPLIDEDPVFITTCTERELRKRKKRKFSLWVRQCSSTGFICQIYVHLKEGPGPDGLDTLKNKPQLHSLVAKQLCQNLAGRNAIIFTGPSITSLNLFQEFEKQGIYCCGLLSIRKSDCTGLPQSMLINTEAPQQRGQSHVKMRGNMSIINWYNKGNFRFLTNAYSPTKEGVIIKRKSGEIPCPLAVEAFAAHLSYICKYDDKYSKYFIFHKPNKTWQQVFWLTISIAINNAYILYKMSDAYHVKRYSRAQFGERLVKELLDMDDCSPTQ", "length": 518 }, "evidence": [ { "id": "A0A1D5P057", "url": "https://omabrowser.org/oma/group/A0A1D5P057/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N414-1", "protein_name": "PiggyBac transposable element-derived protein 5", "gene_name": "PGBD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGGGGARRRAPALLEAARARYESLHISDDVFGESGPDSGGNPFYSTSAASRSSSAASSDDEREPPGPPGAAPPPPRAPDAQEPEEDEAGAGWSAALRDRPPPRFEDTGGPTRKMPPSASAVDFFQLFVPDNVLKNMVVQTNMYAKKFQERFGSDGAWVEVTLTEMKAFLGYMISTSISHCESVLSIWSGGFYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQPFLDSLQNSFDSAFRPSQTQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFIIQIYVHLKEGGGPDGLDALKNKPQLHSMVARSLCRNAAGKNYIIFTGPSITSLTLFEEFEKQGIYCCGLLRARKSDCTGLPLSMLTNPATPPARGQYQIKMKGNMSLICWYNKGHFRFLTNAYSPVQQGVIIKRKSGEIPCPLAVEAFAAHLSYICRYDDKYSKYFISHKPNKTWQQVFWFAISIAINNAYILYKMSDAYHVKRYSRAQFGERLVRELLGLEDASPTH", "length": 524 }, "evidence": [ { "id": "A0A1D5P057", "url": "https://omabrowser.org/oma/group/A0A1D5P057/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transposase activity", "id": "GO:0004803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "non-replicative DNA transposition", "id": "GO:0098038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098038", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P057", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P057-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 642, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P057-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P057" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P057" }, { "id": "PF13843", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PiggyBac transposable element-derived protein", "eco_id": "ECO_0000259", "start_pos": 239, "end_pos": 605, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 314, "end_pos": 316 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 586, "end_pos": 588 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P063-1", "uniprot_ac": "A0A1D5P063", "uniprot_id": "A0A1D5P063_CHICK", "mass": { "chemical_mass": 8804.0, "monoisotopic_mass": 8804.0 }, "refseq": { "ac": "NP_001289104", "name": "small integral membrane protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" }, "gene_names": [ { "name": "SMIM4", "type": "recommended", "evidence": [ { "id": "A0A1D5P063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ] }, { "name": "SMIM4", "type": "synonym", "evidence": [ { "id": "NP_001289104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" } ] }, { "name": "SNHG8", "type": "synonym", "evidence": [ { "id": "NP_001289104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" } ] } ], "protein_names": [ { "name": "Small integral membrane protein 4", "type": "synonym", "evidence": [ { "id": "A0A1D5P063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063/entry#names_and_taxonomy" } ] }, { "name": "small integral membrane protein 4", "type": "synonym", "evidence": [ { "id": "NP_001289104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" } ] }, { "name": "small nucleolar RNA host gene (non-protein coding) 8", "type": "synonym", "evidence": [ { "id": "NP_001289104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AL585703.1, SRR12888512.3893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000250.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMIM4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063", "locus": { "chromosome": "12", "start_pos": 768774, "end_pos": 767813, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028046", "url": "https://www.ensembl.org/id/ENSGALG00010028046" } ] } } ], "crossref": [ { "id": "A0A1D5P063", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P063", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042863", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415896", "url": "https://www.ncbi.nlm.nih.gov/gene/415896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415896", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEWFMIK", "url": "https://omabrowser.org/oma/group/MEWFMIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P063", "url": "https://www.orthodb.org/?gene=A0A1D5P063", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35250:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35250:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289104", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P063-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVSRRLKRLLRLVPGRERLGAYRLLPFFFVLGGAMEWFMINVRIGKETFYDVYRRKRSERQYEARMEKSES", "length": 72, "header": "tr|A0A1D5P063-1|A0A1D5P063_CHICK Isoform 1 of Small integral membrane protein 4 OS=Gallus gallus OX=9031 GN=SMIM4 PE=4 SV=1 CANONICAL=A0A1D5P063-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P063-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063/entry", "sequence": { "sequence": "MLVSRRLKRLLRLVPGRERLGAYRLLPFFFVLGGAMEWFMINVRIGKETFYDVYRRKRSERQYEARMEKSES", "length": 72, "header": "tr|A0A1D5P063-1|A0A1D5P063_CHICK Isoform 1 of Small integral membrane protein 4 OS=Gallus gallus OX=9031 GN=SMIM4 PE=4 SV=1 CANONICAL=A0A1D5P063-1" }, "locus": { "chromosome": "12", "start_pos": 768535, "end_pos": 768080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067961.1", "url": "https://www.ensembl.org/id/ENSGALT00010067961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041704.1", "url": "https://www.ensembl.org/id/ENSGALP00010041704.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415896", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415896", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M3J2-1", "protein_name": "Small integral membrane protein 4", "gene_name": "Smim4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSRAQVRRALQWVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDTSETHLHKIK", "length": 79 }, "evidence": [ { "id": "A0A1D5P063", "url": "https://omabrowser.org/oma/group/A0A1D5P063/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1R6M1-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "UQCC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSRAQVRRVLQRVPGKQRLGVYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDASETELQQSIK", "length": 80 }, "evidence": [ { "id": "A0A1D5P063", "url": "https://omabrowser.org/oma/group/A0A1D5P063/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A1D5P063", "url": "https://omabrowser.org/oma/group/A0A1D5P063/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WVI0-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "UQCC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFTRAQVRRILQRVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDE", "length": 70 }, "evidence": [ { "id": "A0A1D5P063", "url": "https://omabrowser.org/oma/group/A0A1D5P063/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3T5-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "sloth1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSPYSGSVRRLLDSWPGKKRFGVYRFLPLFFLLGAGLEFSMINWTVGETNFYRTFKRRQAKNYVEEQQHLQARAANNTN", "length": 79 }, "evidence": [ { "id": "A0A1D5P063", "url": "https://omabrowser.org/oma/group/A0A1D5P063/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mitochondrial ribosome binding", "id": "GO:0097177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097177", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P063", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P063" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P063-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 72, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P063-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P063" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P0L5-1", "uniprot_ac": "A0A1D5P0L5", "uniprot_id": "A0A1D5P0L5_CHICK", "mass": { "chemical_mass": 22236.0, "monoisotopic_mass": 22236.0 }, "refseq": { "ac": "XP_015147265", "name": "ADP-ribosylation factor-like protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147265" }, "gene_names": [ { "name": "ARL14", "type": "recommended", "evidence": [ { "id": "A0A1D5P0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ] }, { "name": "ARL14", "type": "synonym", "evidence": [ { "id": "XP_015147265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147265" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 14", "type": "recommended", "evidence": [ { "id": "A0A1D5P0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor 7", "type": "synonym", "evidence": [ { "id": "A0A1D5P0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like protein 14", "type": "synonym", "evidence": [ { "id": "XP_015147265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147265" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147265" } ] }, { "annotation": "GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5#function" }, { "database": "UniProtKB", "id": "ARBA00054077", "url": "https://www.uniprot.org/uniprotkb/ARBA00054077#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5", "locus": { "chromosome": "9", "start_pos": 21832173, "end_pos": 21813523, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001163", "url": "https://www.ensembl.org/id/ENSGALG00010001163" } ] } } ], "crossref": [ { "id": "A0A1D5P0L5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P0L5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043623", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043623", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101749876", "url": "https://www.ncbi.nlm.nih.gov/gene/101749876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749876", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749876", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AQIIMLG", "url": "https://omabrowser.org/oma/group/AQIIMLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P0L5", "url": "https://www.orthodb.org/?gene=A0A1D5P0L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147265", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLQITKHSKVKQANILMLGLDSAGKSTLLYKFKSDEVFLTIPTIGFNVDMIETGKDFTLTFWDVGGQEKMRQRWCNFLENAEALLYVVDSADKQRLEESKKEFELLLKNESIKNVPVIVLANKQDLPGALNAEEITRRFHVKKYCCDRNWYVQPCCAVTGEGLSEALQRLTAFAKHYSRSKEISTSFKENEKR", "length": 194, "header": "tr|A0A1D5P0L5-1|A0A1D5P0L5_CHICK Isoform 1 of ADP-ribosylation factor-like protein 14 OS=Gallus gallus OX=9031 GN=ARL14 PE=3 SV=1 CANONICAL=A0A1D5P0L5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5/entry", "sequence": { "sequence": "MGLQITKHSKVKQANILMLGLDSAGKSTLLYKFKSDEVFLTIPTIGFNVDMIETGKDFTLTFWDVGGQEKMRQRWCNFLENAEALLYVVDSADKQRLEESKKEFELLLKNESIKNVPVIVLANKQDLPGALNAEEITRRFHVKKYCCDRNWYVQPCCAVTGEGLSEALQRLTAFAKHYSRSKEISTSFKENEKR", "length": 194, "header": "tr|A0A1D5P0L5-1|A0A1D5P0L5_CHICK Isoform 1 of ADP-ribosylation factor-like protein 14 OS=Gallus gallus OX=9031 GN=ARL14 PE=3 SV=1 CANONICAL=A0A1D5P0L5-1" }, "locus": { "chromosome": "9", "start_pos": 21834685, "end_pos": 21832173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002654.1", "url": "https://www.ensembl.org/id/ENSGALT00010002654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001204.1", "url": "https://www.ensembl.org/id/ENSGALP00010001204.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749876", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749876", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N188-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "ARL14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLLNSKKPKAKQARILLLGLDSAGKSTLLYKLKLDKDIVTIPTVGFNVEMIELAKGVSLTVWDVGGQEKMRATWGLYCENTDGLVYVVDSTDTQRLEDSRKEFEHILKNEYIKNVPVVLLANKQDMPGALSAEDITRMFKVKQLCSDRNWCVQPCCAVTGDGLMEGFQKLTGFVKSHMKSRGDTLAFFKQH", "length": 192 }, "evidence": [ { "id": "A0A1D5P0L5", "url": "https://omabrowser.org/oma/group/A0A1D5P0L5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HHC2-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "Arl14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLQSSKNPTGKQAHILLLGLDSAGKSTLLYRLKLAETFTTIPTIGFNVEMVQLPSGLPLTVWDVGGQEKMRTVWDCYCENADGLVYVVDCSDDKRRLEDSRREFKHILKNEHIKNAPVVILANKQDLPGALSAEDITRMFKVKKLCSNRNWYVQPCSAVTGEGLDAGFRKLTEFVKSHLKTRDTLAFFKQK", "length": 192 }, "evidence": [ { "id": "A0A1D5P0L5", "url": "https://omabrowser.org/oma/group/A0A1D5P0L5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R6N0-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "Arl14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLSSKNPKDKQAHILLLGLDSAGKSTLLYRLKFAETLATIPTIGFNVEMVQLQSGLALTVWDIGGQEKMRTVWDCYCENAHGLVYVVDCSEGQKRLEDSRKEFKHILKNEHIKNTPVVILANKQDLPGALSAEDITRMFKVKKLCSDRNWYVQPCCAVTGEGLDDGFRKLTEFVKSHLKTRETLAFFKQK", "length": 192 }, "evidence": [ { "id": "A0A1D5P0L5", "url": "https://omabrowser.org/oma/group/A0A1D5P0L5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SXC5-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "Arl14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLNSKNPQSKQAHILLLGLDSAGKSTLLYRLKFAETLATIPTIGFNVEMVQLQSSLTLTVWDVGGQEKMRTVWDCYCENAQGLMYVVDCSEGKKRLEDSRKEFKHILKNEHIKNTPVVILANKQDLPGALSAEDITRMFKVKKLCSNRNWYVQPCCAVTGEGLDDGFRKLTEFLKSYRRTRETLAIFKQK", "length": 192 }, "evidence": [ { "id": "A0A1D5P0L5", "url": "https://omabrowser.org/oma/group/A0A1D5P0L5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4G2-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "ARL14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN", "length": 192 }, "evidence": [ { "id": "A0A1D5P0L5", "url": "https://omabrowser.org/oma/group/A0A1D5P0L5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P0L5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P0L5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P0L5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A1D5P0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 27, "amino_acid": "Ser", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 27, "end_pos": 27, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5P0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0L5" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 44, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 44, "end_pos": 44, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"id": "A0A1D5P0X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ELL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6", "locus": { "chromosome": "Z", "start_pos": 58137703, "end_pos": 58081286, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012711", "url": "https://www.ensembl.org/id/ENSGALG00010012711" } ] } } ], "crossref": [ { "id": "A0A1D5P0X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P0X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014678", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427119", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P0X6", "url": "https://www.orthodb.org/?gene=A0A1D5P0X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFF8", "url": "https://www.orthodb.org/?gene=A0A8V0YFF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFG3", "url": "https://www.orthodb.org/?gene=A0A8V0YFG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFI4", "url": "https://www.orthodb.org/?gene=A0A8V0YFI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF5", "url": "https://www.orthodb.org/?gene=A0A8V0YNF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P0X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLREGGRYAVSCGKAADNVSVLHVKLTETAVRALESYQSRKDLVPSQPSIQFQGRQGLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQVCVAPGLWELETAGMGCSLFLSKGHEILNFRYFHALIFFLSLQSSPNYREEKHRCEYLHNKLSHIKRLIGEFDQQQSELRH", "length": 679, "header": "tr|A0A1D5P0X6-1|A0A1D5P0X6_CHICK Isoform 1 of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P0X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6/entry", "sequence": { "sequence": "MASLREGGRYAVSCGKAADNVSVLHVKLTETAVRALESYQSRKDLVPSQPSIQFQGRQGLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQVCVAPGLWELETAGMGCSLFLSKGHEILNFRYFHALIFFLSLQSSPNYREEKHRCEYLHNKLSHIKRLIGEFDQQQSELRH", "length": 679, "header": "tr|A0A1D5P0X6-1|A0A1D5P0X6_CHICK Isoform 1 of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "locus": { "chromosome": "Z", "start_pos": 58134434, "end_pos": 58081424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030424.1", "url": "https://www.ensembl.org/id/ENSGALT00010030424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017645.1", "url": "https://www.ensembl.org/id/ENSGALP00010017645.1" } ] } }, { "isoform_ac": "A0A8V0YFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF8/entry", "sequence": { "sequence": "MVHIQNDNKTSLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQSSPNYREEKHRCEYLHNKLSHIKRLIGEFDQQQSELRH", "length": 588, "header": "tr|A0A8V0YFF8-1|A0A1D5P0X6_CHICK Computationally mapped isoform of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "locus": { "chromosome": "Z", "start_pos": 58134434, "end_pos": 58093955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030406.1", "url": "https://www.ensembl.org/id/ENSGALT00010030406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017633.1", "url": "https://www.ensembl.org/id/ENSGALP00010017633.1" } ] } }, { "isoform_ac": "A0A8V0YFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG3/entry", "sequence": { "sequence": "MSSDLVPSQPSIQFQGRQGLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQSSPNYREEKHRCEYLHNKLSHIKRLIGEFDQQQSELRH", "length": 596, "header": "tr|A0A8V0YFG3-1|A0A1D5P0X6_CHICK Computationally mapped isoform of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "locus": { "chromosome": "Z", "start_pos": 58134434, "end_pos": 58081827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030415.1", "url": "https://www.ensembl.org/id/ENSGALT00010030415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017638.1", "url": "https://www.ensembl.org/id/ENSGALP00010017638.1" } ] } }, { "isoform_ac": "A0A8V0YFI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI4/entry", "sequence": { "sequence": "MASLREGGRYAVSCGKAADNVSVLHVKLTETAVRALESYQSRKDLVPSQPSIQFQGRQGLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQSSPNYREEKHRCEYLHNKLSHIKRLIAGG", "length": 627, "header": "tr|A0A8V0YFI4-1|A0A1D5P0X6_CHICK Computationally mapped isoform of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "locus": { "chromosome": "Z", "start_pos": 58136544, "end_pos": 58081424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030436.1", "url": "https://www.ensembl.org/id/ENSGALT00010030436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017653.1", "url": "https://www.ensembl.org/id/ENSGALP00010017653.1" } ] } }, { "isoform_ac": "A0A8V0YNF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF5/entry", "sequence": { "sequence": "MASLREGGRYAVSCGKAADNVSVLHVKLTETAVRALESYQSRKDLVPSQPSIQFQGRQGLIKIPKVDHPNESHTFNFYLSNVGKDNPQGSFDCVQQTASSSGASQLSSLGLIQNKITVCATNDSYQMTKERMTQAEEELRNRSAKVIKPGGPYLGKRVQIRKAPQSIPDPVPERKRSTPINPANTIRRTHANNAVSQRPYRDRVIHLLALKTYKKPELLARLQRDGVNLKDRNSLTAVLQQVANLNPKDNSYTLKDYLYKDIQKDWPGYNEVDKQTLELILSRKVNSSQSTTSTSHLGSPVTSNKDAPSASPSQKRLSDFNFIDPLMNKKPRISHLSSRLQPSLSGHPPAPSKKAAPATAAPTPPSLPAAHPPASNPPQTASSISPNTPEGRGTQDLPVDSISQSGSSVFKHQQEKYTSRTPLETPAAAAGNSEHPTLAGEEDVALCKKSTKKAKKHKEKDQIKQQDTTREQKDEGLLESKTDLRKEEAATMKSPSGLASDGGVEKTCTASTESPSSTNELPDYFKKYIAIVSYEQRQSYKDDFNAEYDEYRNLHARMESITRKFMKLDEQRKQLSPGSKEYQMLHEEVLEEYRKIQQLEVNAT", "length": 604, "header": "tr|A0A8V0YNF5-1|A0A1D5P0X6_CHICK Computationally mapped isoform of Elongation factor for RNA polymerase II 2 OS=Gallus gallus OX=9031 GN=ELL2 PE=3 SV=1 CANONICAL=A0A1D5P0X6-1" }, "locus": { "chromosome": "Z", "start_pos": 58136554, "end_pos": 58081424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030431.1", "url": "https://www.ensembl.org/id/ENSGALT00010030431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017650.1", "url": "https://www.ensembl.org/id/ENSGALP00010017650.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427119", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P0X6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 679, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P0X6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P0X6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 363 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P134-1", "uniprot_ac": "A0A1D5P134", "uniprot_id": "A0A1D5P134_CHICK", "mass": { "chemical_mass": 89591.0, "monoisotopic_mass": 89591.0 }, "refseq": { "ac": "XP_024999697", "name": "leucine-zipper-like transcriptional regulator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999697" }, "gene_names": [ { "name": "LZTR1", "type": "recommended", "evidence": [ { "id": "A0A1D5P134", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ] }, { "name": "LZTR1", "type": "synonym", "evidence": [ { "id": "XP_024999697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999697" } ] } ], "protein_names": [ { "name": "Leucine zipper like post translational regulator 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P134", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134/entry#names_and_taxonomy" } ] }, { "name": "leucine-zipper-like transcriptional regulator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024999697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999697" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999697.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LZTR1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134", "locus": { "chromosome": "26", "start_pos": 652057, "end_pos": 632451, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026117", "url": "https://www.ensembl.org/id/ENSGALG00010026117" } ] } } ], "crossref": [ { "id": "A0A1D5P134", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P134", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031175", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18308", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18308", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18309", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18309", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18505", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18505", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421166", "url": "https://www.ncbi.nlm.nih.gov/gene/421166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421166", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKEAIYV", "url": "https://omabrowser.org/oma/group/YKEAIYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P134", "url": "https://www.orthodb.org/?gene=A0A1D5P134", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH5", "url": "https://www.orthodb.org/?gene=A0A8V1AAH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P134-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGTPAGGAGRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYRDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKTEGRLPVARSAHGATVYSEKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEIEQSGEIPPSCCNFPVAVCKDKMFVFSGQSGAKITNNLFQFEFKEKIWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDSQTWEVIQPSPDSELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWENRQFSDLEFVLGEKEERVRGHTAIVTARCKWLKKKIMQARERLKQKSKQDIEDEGQAVCQKDGIGGNVKLCRLQPLLEVPIREAEAQPFEVLMQFLYTDKIKYPRKGHVQDVLLIMDVYKLALNFKLSRLEQLCLQYIEASVDLQNVLIVCENANKLQLDQLKEHCLNFVVKESHFNQVIMMKEFEHLSSSLIVEIVRRKQQPPVRTHSDQPLDIGTSLIQDMKAYLEGAGIEFCDIILLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSKQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFSNNRLQAYCKQNLEMNVTVENVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPNLRSLSQPLLLDIIESLANHISDKQCAELGSDI", "length": 786, "header": "tr|A0A1D5P134-1|A0A1D5P134_CHICK Isoform 1 of Leucine zipper like post translational regulator 1 OS=Gallus gallus OX=9031 GN=LZTR1 PE=4 SV=2 CANONICAL=A0A1D5P134-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P134-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134/entry", "sequence": { "sequence": "MAAAGTPAGGAGRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYRDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKTEGRLPVARSAHGATVYSEKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEIEQSGEIPPSCCNFPVAVCKDKMFVFSGQSGAKITNNLFQFEFKEKIWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDSQTWEVIQPSPDSELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWENRQFSDLEFVLGEKEERVRGHTAIVTARCKWLKKKIMQARERLKQKSKQDIEDEGQAVCQKDGIGGNVKLCRLQPLLEVPIREAEAQPFEVLMQFLYTDKIKYPRKGHVQDVLLIMDVYKLALNFKLSRLEQLCLQYIEASVDLQNVLIVCENANKLQLDQLKEHCLNFVVKESHFNQVIMMKEFEHLSSSLIVEIVRRKQQPPVRTHSDQPLDIGTSLIQDMKAYLEGAGIEFCDIILLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSKQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFSNNRLQAYCKQNLEMNVTVENVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPNLRSLSQPLLLDIIESLANHISDKQCAELGSDI", "length": 786, "header": "tr|A0A1D5P134-1|A0A1D5P134_CHICK Isoform 1 of Leucine zipper like post translational regulator 1 OS=Gallus gallus OX=9031 GN=LZTR1 PE=4 SV=2 CANONICAL=A0A1D5P134-1" }, "locus": { "chromosome": "26", "start_pos": 651372, "end_pos": 632491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063629.1", "url": "https://www.ensembl.org/id/ENSGALT00010063629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039277.1", "url": "https://www.ensembl.org/id/ENSGALP00010039277.1" } ] } }, { "isoform_ac": "A0A8V1AAH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH5/entry", "sequence": { "sequence": "MAAAGTPAGGAGRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYRDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKTEGRLPVARSAHGATVYSEKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEIEQSGEIPPSCCNFPVAVCKDKMFVFSGQSGAKITNNLFQFEFKEKIWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDSQTWEVIQPSPDSELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWENRQFSDLEFVLGEKEERVRGHTAIVTARCKWLKKKIMQARERLKQKSKQDIEDEGQAVCQKDGIGGNVKLCRLQPLLEVPIREAEAQPFEVLMQFLYTDKIKYPRKGHVQDVLLIMDVYKLALNFKLSRLEQLCLQYIEASVDLQNVLIVCENANKLQLDQLKEHCLNFVVKESHFNQVIMMKEFEHLSSSLIVEIVRRKQQPPVRTHSDQPLDIGTSLIQDMKAYLEGAGIEFCDIILLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSKQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFSNNRLQAYCKQNLEMNVTVENVLQILEAADKTQALDMKRHCLHIIVHQFTKLRHGCVSLALADKSARHASHMNNK", "length": 772, "header": "tr|A0A8V1AAH5-1|A0A1D5P134_CHICK Computationally mapped isoform of Leucine zipper like post translational regulator 1 OS=Gallus gallus OX=9031 GN=LZTR1 PE=4 SV=1 CANONICAL=A0A1D5P134-1" }, "locus": { "chromosome": "26", "start_pos": 648794, "end_pos": 632491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063627.1", "url": "https://www.ensembl.org/id/ENSGALT00010063627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039276.1", "url": "https://www.ensembl.org/id/ENSGALP00010039276.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421166", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HG01-1", "protein_name": "Leucine-zipper-like transcriptional regulator 1", "gene_name": "Lztr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGPGGSGAQIGPGALAGGLRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKVEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERASSSEEASILTSEERSSFKKSRDVFGLDFGTTSAKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKILQAQEWLAQKLEEDGALAPREAPGSAVGRARPPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGTSLIQDMKAYLEGAGSDFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRLLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 840 }, "evidence": [ { "id": "A0A1D5P134", "url": "https://omabrowser.org/oma/group/A0A1D5P134/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8N653-1", "protein_name": "Leucine-zipper-like transcriptional regulator 1", "gene_name": "LZTR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSRDVFGLDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARERLAQKLEQEAAPVPREAPGVAAGGARPPLLHVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLSQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPLDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 840 }, "evidence": [ { "id": "A0A1D5P134", "url": "https://omabrowser.org/oma/group/A0A1D5P134/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQ33-1", "protein_name": "Leucine-zipper-like transcriptional regulator 1", "gene_name": "Lztr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSGGPIGSGALTGGVRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEMPERASSSEDASTLTSEERSSFKKSRDVFGLDFGTTSAKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKIVQAQEWLAQKLEEDGALAPKEAPGPAVGRARPPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPSDQPVDIGTSLIQDMKAYLEGAGSEFCDITLLLDGQPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRLLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 837 }, "evidence": [ { "id": "A0A1D5P134", "url": "https://omabrowser.org/oma/group/A0A1D5P134/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V410-1", "protein_name": "Leucine-zipper-like transcriptional regulator 1 homolog", "gene_name": "Lztr1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKSISGGVGVASTERGGGGGGCGGGGAGGSASGSRSTSGSGRASCGLGSSSISSGLSAVCGFVTGASGGGGFERDRDRDRGLANISGGSTPAGILYCPACMAAANQQSPSQNSSPHHESFFLRSSFKSSKRNKARKSASTAGCLDAQHIRANLRMSMSSSMRSSRGNGGGGAASSSHPPGSSCSSGPGGSGCSMAYDAASNASSGSGSGSGKATSPGSYSCNALNVDFTSYTATHQWTRMLECAEFVGAKRSKHTVVAYKDAMFVFGGDNGKNMLNDLIRFGVKDKSWGRACATGTPPAPRYHHSAVVAGSSMFIFGGYTGDIHSNSNLTNKNDLFEYKFQSAMWVEWKFSGRQPVPRSAHGAAVYDNKMWIYAGYDGNARLNDMWTLNLTGENQWEEVDQLGDRPPTCCNFPVAVARDAMYVFSGQSGLQITNSLFEFHFKTRTWRRISNEPVLRGATSAPPSRRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQVWSVIQPEQNSDVPSGRVFHASAVICDAMYIFGGTVDNSVRRGDTYRFQFSSYPKCTLRDDFGKFFQDKQFCDIQFIVGAEEIRILAHIAFVAARSKYLRNKILAAREARQQQMEKVYGVGQVDALALNAGAGGDRGPMLEVRLANASPEAFEIILNYIYTDRIDLKDTYSKNIIILITDIYQLAGLFTMPRLAHGCIQYLDYKINKLNVLEALYNADKSNIKIIKDHCMQFIIKEENFTDVVMSSEFSDLDKPLLVEIIRKRLYPSKLVIDTSYEGNIGTTLEIDLCAFLESTGKDFCDISLVLEDHVIPAHKSVLSSRCTYFQGMFRSFMPPDNTVNIQIGEISPSLEAFHSLLRYIYYGETKMPPQDALYLFQAPCFYGLANNRLHAFCKYSLEHNITFENVLQTLEASDITKIYDIKEYALKLIVKDFAKVARLPKIAGLSRELLLEIIRAVADSHGEFLTRININTDI", "length": 975 }, "evidence": [ { "id": "A0A1D5P134", "url": "https://omabrowser.org/oma/group/A0A1D5P134/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P134", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P134-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 786, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P134-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P134" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P134", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P134" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 483, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 6 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 653, "end_pos": 655 }, { "start_pos": 713, "end_pos": 715 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P1Q3-1", "uniprot_ac": "A0A1D5P1Q3", "uniprot_id": "A0A1D5P1Q3_CHICK", "mass": { "chemical_mass": 154295.0, "monoisotopic_mass": 154295.0 }, "refseq": { "ac": "XP_414022", "name": "enhancer of mRNA-decapping protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414022" }, "gene_names": [ { "name": "EDC4", "type": "recommended", "evidence": [ { "id": "A0A1D5P1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ] }, { "name": "EDC4", "type": "synonym", "evidence": [ { "id": "XP_414022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414022" } ] } ], "protein_names": [ { "name": "Enhancer of mRNA-decapping protein 4", "type": "recommended", "evidence": [ { "id": "A0A1D5P1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3/entry#names_and_taxonomy" } ] }, { "name": "enhancer of mRNA-decapping protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_414022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_414022.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EDC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3", "locus": { "chromosome": "11", "start_pos": 972104, "end_pos": 940306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021908", "url": "https://www.ensembl.org/id/ENSGALG00010021908" } ] } } ], "crossref": [ { "id": "ENSGALG00000040875", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040875", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415656", "url": "https://www.ncbi.nlm.nih.gov/gene/415656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415656", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TREHMGT", "url": "https://omabrowser.org/oma/group/TREHMGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1Q3", "url": "https://www.orthodb.org/?gene=A0A1D5P1Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PW21", "url": "https://www.orthodb.org/?gene=A0A1D5PW21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PW21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PW21-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSNSIDIEDATQHLRDILKLDRPGGSVNENQRPSSSYNGDLNGLLVPDPLVAGDGPALAKPVHRSISLGAVQEKQVICLSGDDSSTCIVISAKDVEIVASSDSSITSKARGSNKVKIQPVARYDWEQKYYYGNLIAVSNSYLAYAIRAASNGSAMVRVLSVSTAERTLLKGFTGGVADLAFAHLNSNQLACLDEAGNLFVWRLAMEEDKIQEEILVNIKRPDGTPLNTSRRIIWCPFIPDDNEENSEEGSQTLALLHEDRAEVWDLDIIRSNNRSWPVEVPNIKEGFIVVKGHSTYLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTVRFSPDIFSSMSILPSLKVCLDLSAEYLILSDVQRKVLYVMELMQNQEKGKAYFSSISEFLLTHPVLSFGIQAVSRCRLRHTEVLPAEEENDNLSIEGAQGAGAVESAAGVLIKLFCVHTKALQDVQIRFQPLHSPDMGASVPSHGSHEEFAFPDHIADLGAEGLGSEKGSVHGSQPDLRRIADLPVPADFLSLSNDAKPKLMTPDAFMTPSTSLQQITVSPGSSVSSLTAVTAMSSTSVTDASMSRPSEDLTVSPKMQLDTSLTLSSSSSSLQTSPRSHSVLIPGLPDKLTPKAPVPVTPGGNSSLALELQEVEPLVVPQASPTRERSPDVISSASTAMSQDIPEIASETLQRSFAAAPPALSAEVLEPSHHADSMASAASALHLLSPRNRHNSEHSHHSLDMPPVEVDRLNAPSLLETALTQENASLDSVVSQPWPAAPDITRETRNSMADSPRDEVEEKHKSSSYHRHSYHLLQHDSQDASAEQSDHDDEVASLASTSGGFGAKASTQRLPMKDWKAKASPRASPKLKRKGKKDDGDVNQSPRSSNNQVTPEFQEELMCVLRSQQRELSELRQNQMELLQRLTDHLDAVQSSLMGHMERVIDSQQEQEQRRLDRALTEGQQRNGQLQEHLSQQLSQTLSSAVCNRLERTVREEMKKTVPQCISKSVDPVAGQLSSTIATKLTAVEGTLKENITKLVKSKNLTDSVVRATADTLQGPIQSAYREAFQSVVLPAFEKSCQSMFQQINDTFKQGTQEYIQQLETHMKNKKAREQEARDPLLNQLRQLISTFQSSTEQLASTIAANIHAEVQHQLHIIVGNLQESILTQVQRVIKGEVSLAMKEQQAAVTSSIVQAMRSAAGTPIPSTHLDFQSQQTHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDTQQVFGQQPCPLSQPVLLSLIQQLSSDLGTRTELKLNYLEEAVMHLDHSDPITRDHMGSVMSQVRQKLFQFLQVEPHNTLSKPARRLMIMLQGLVTPGMT", "length": 1403, "header": "tr|A0A1D5P1Q3-1|A0A1D5P1Q3_CHICK Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Gallus gallus OX=9031 GN=EDC4 PE=1 SV=1 CANONICAL=A0A1D5P1Q3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3/entry", "sequence": { "sequence": "MASSNSIDIEDATQHLRDILKLDRPGGSVNENQRPSSSYNGDLNGLLVPDPLVAGDGPALAKPVHRSISLGAVQEKQVICLSGDDSSTCIVISAKDVEIVASSDSSITSKARGSNKVKIQPVARYDWEQKYYYGNLIAVSNSYLAYAIRAASNGSAMVRVLSVSTAERTLLKGFTGGVADLAFAHLNSNQLACLDEAGNLFVWRLAMEEDKIQEEILVNIKRPDGTPLNTSRRIIWCPFIPDDNEENSEEGSQTLALLHEDRAEVWDLDIIRSNNRSWPVEVPNIKEGFIVVKGHSTYLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTVRFSPDIFSSMSILPSLKVCLDLSAEYLILSDVQRKVLYVMELMQNQEKGKAYFSSISEFLLTHPVLSFGIQAVSRCRLRHTEVLPAEEENDNLSIEGAQGAGAVESAAGVLIKLFCVHTKALQDVQIRFQPLHSPDMGASVPSHGSHEEFAFPDHIADLGAEGLGSEKGSVHGSQPDLRRIADLPVPADFLSLSNDAKPKLMTPDAFMTPSTSLQQITVSPGSSVSSLTAVTAMSSTSVTDASMSRPSEDLTVSPKMQLDTSLTLSSSSSSLQTSPRSHSVLIPGLPDKLTPKAPVPVTPGGNSSLALELQEVEPLVVPQASPTRERSPDVISSASTAMSQDIPEIASETLQRSFAAAPPALSAEVLEPSHHADSMASAASALHLLSPRNRHNSEHSHHSLDMPPVEVDRLNAPSLLETALTQENASLDSVVSQPWPAAPDITRETRNSMADSPRDEVEEKHKSSSYHRHSYHLLQHDSQDASAEQSDHDDEVASLASTSGGFGAKASTQRLPMKDWKAKASPRASPKLKRKGKKDDGDVNQSPRSSNNQVTPEFQEELMCVLRSQQRELSELRQNQMELLQRLTDHLDAVQSSLMGHMERVIDSQQEQEQRRLDRALTEGQQRNGQLQEHLSQQLSQTLSSAVCNRLERTVREEMKKTVPQCISKSVDPVAGQLSSTIATKLTAVEGTLKENITKLVKSKNLTDSVVRATADTLQGPIQSAYREAFQSVVLPAFEKSCQSMFQQINDTFKQGTQEYIQQLETHMKNKKAREQEARDPLLNQLRQLISTFQSSTEQLASTIAANIHAEVQHQLHIIVGNLQESILTQVQRVIKGEVSLAMKEQQAAVTSSIVQAMRSAAGTPIPSTHLDFQSQQTHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDTQQVFGQQPCPLSQPVLLSLIQQLSSDLGTRTELKLNYLEEAVMHLDHSDPITRDHMGSVMSQVRQKLFQFLQVEPHNTLSKPARRLMIMLQGLVTPGMT", "length": 1403, "header": "tr|A0A1D5P1Q3-1|A0A1D5P1Q3_CHICK Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Gallus gallus OX=9031 GN=EDC4 PE=1 SV=1 CANONICAL=A0A1D5P1Q3-1" }, "locus": { "chromosome": "11", "start_pos": 971405, "end_pos": 940376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053286.1", "url": "https://www.ensembl.org/id/ENSGALT00010053286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032114.1", "url": "https://www.ensembl.org/id/ENSGALP00010032114.1" } ] } }, { "isoform_ac": "A0A1D5PW21-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW21/entry", "sequence": { "sequence": "MASSNSIDIEDATQHLRDILKLDRPGGSVNENQRPSSSYNGDLNGLLVPDPLVAGDGPALAKPVHRSISLGAVQEKQVICLSGDDSSTCIVISAKDVEIVASSDSSITSKARGSNKVKIQPVARYDWEQKYYYGNLIAVSNSYLAYAIRAASNGSAMVRVLSVSTAERTLLKGFTGGVADLAFAHLNSNQLACLDEAGNLFVWRLAMEEDKIQEEILVNIKRPDGTPLNTSRRIIWCPFIPDDNEENSEEGSQTLALLHEDRAEVWDLDIIRSNNRSWPVEVPNIKEGFIVVKGHSTYLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTVRFSPDIFSSMSILPSLKVCLDLSAEYLILSDVQRKVLYVMELMQNQEKGKAYFSSISEFLLTHPVLSFGIQAVSRCRLRHTEVLPAEEENDNLSIEGAQGAGAVESAAGVLIKLFCVHTKALQDVQIRFQPLHSPDMGASVPSHGSHEEFAFPDHIADLGAEGLGSEKGSVHGSQPDLRRIADLPVPADFLSLSNDAKPKLMTPDAFMTPSTSLQQITVSPGSSVSSLTAVTAMSSTSVTDASMSRPSEDLTVSPKMQLDTSLTLSSSSSSLQTSPRSHSVLIPGLPDKLTPKAPVPVTPGGNSSLALELQEVEPLVVPQASPTRERSPDVISSASTAMSQDIPEIASETLQRSFAAAPPALSAEVLEPSHHADSMASAASALHLLSPRNRHNSEHSHHSLDMPPVEVDRLNAPSLLETALTQENASLDSVVSQPWPAAPDITRETRNSMADSPRDEVEEKHKSSSYHRHSYHLLQHDSQDASAEQRDVNQSPRSSNNQVTPEFQEELMCVLRSQQRELSELRQNQMELLQRLTDHLDAVQSSLMGHMERVIDSQQEQEQRRLDRALTEGQQRNGQLQEHLSQQLSQTLSSAVCNRLERTVREEMKKTVPQCISKSVDPVAGQLSSTIATKLTAVEGTLKENITKLVKSKNLTDSVVRATADTLQGPIQSAYREAFQSVVLPAFEKSCQSMFQQINDTFKQGTQEYIQQLETHMKNKKAREQEARDPLLNQLRQLISTFQSSTEQLASTIAANIHAEVQHQLHIIVGNLQESILTQVQRVIKGEVSLAMKEQQAAVTSSIVQAMRSAAGTPIPSTHLDFQSQQTHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDTQQVFGQQPCPLSQPVLLSLIQQLSSDLGTRTELKLNYLEEAVMHLDHSDPITRDHMGSVMSQVRQKLFQFLQVEPHNTLSKPARRLMIMLQGLVTPGMT", "length": 1352, "header": "tr|A0A1D5PW21-1|A0A1D5PW21_CHICK Computationally mapped isoform of Enhancer of mRNA-decapping protein 4 OS=Gallus gallus OX=9031 GN=EDC4 PE=1 SV=1 CANONICAL=A0A1D5P1Q3-1" }, "locus": { "chromosome": "11", "start_pos": 971405, "end_pos": 940376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053282.1", "url": "https://www.ensembl.org/id/ENSGALT00010053282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032111.1", "url": "https://www.ensembl.org/id/ENSGALP00010032111.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 692, "start_aa": "Thr", "end_pos": 692, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr692", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415656", "resource": "KEGG Pathway" }, { "id": "R-GGA-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BJH1-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAENQRPSNAYNGDLNGLLVPDPLCSGDSASTNKPGFRAMPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1400 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S2J4-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAESQRPSNAYNGDLNGLLVPDPLCSGDGTSANKPGLRAMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHVNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRSNHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGCACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEETDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHPAHEDFAFGESRSELGSEGLGSTTHGSQPDLRRIVELPAPANFLSLSNETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTISSSSSLQASPRGLLPGLLPGPADKLTPKGPGQVLTAASALSLELQEMEPLGLPQASPTRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGGPGDGDRHSAPSLLEAALTQETTAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGGFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSMGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCTQLEGLQSTVMGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKESISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQGATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1402 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UJB9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNAESQRPSSAYNGDLNGLLVPDPLSSGDGNSTNKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVKGKIQEEILVHIRQPEGTALNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGTESSHGAGALESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAAHGSQPDLRRIVELPAPADFLSLSSETKPELMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPRPPEELTLSPKLQLDGSLTLNSSSSSLQASPRSLLPGLLPGPADKLISKGPGQVSTAASALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPNSMASAASALHLLSPRPRQGPELGSQLGLDGGPGDGDRHSTPSLLEAALTQEVATPDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPSKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVAEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLSKAARRLSLMLHGLVTPSLP", "length": 1406 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZAV8-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNVESQRPSSAYNGDLNGLLVPDPLSSGDGNSTSKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGDLFVWRLALVKGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEESDSLGTESSHGAGTLESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAPHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPSRPPEELTLSPKLQLDGSLTISSSSSLQASPRSLLPGLLPGPADKLIPKGPGQVSSGTSALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPDSMASAASALHLLSPRPRQGPELSSQLGLDGGPGDGDRHSTPSLLEAALTQEVATSDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVVEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLDSHMKSRKAREQEAREPVLAQLRGLVSTLQNATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1407 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P2E9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1401 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKK1-1", "protein_name": "Enhancer of mRNA-decapping protein 4 homolog", "gene_name": "Ge-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK", "length": 1354 }, "evidence": [ { "id": "A0A1D5P1Q3", "url": "https://omabrowser.org/oma/group/A0A1D5P1Q3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": 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"https://www.ncbi.nlm.nih.gov/protein/XP_015141509" }, "gene_names": [ { "name": "RNF212", "type": "recommended", "evidence": [ { "id": "A0A1D5P1V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9" } ] }, { "name": "RNF212", "type": "synonym", "evidence": [ { "id": "XP_015141509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141509" } ] } ], "protein_names": [ { "name": "Ring finger protein 212", "type": "synonym", "evidence": [ { "id": "A0A1D5P1V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9/entry#names_and_taxonomy" } ] }, { "name": "probable E3 SUMO-protein ligase RNF212 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015141509.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1V9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF212", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9", "locus": { "chromosome": "4", "start_pos": 84438186, "end_pos": 84418973, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017689", "url": "https://www.ensembl.org/id/ENSGALG00010017689" } ] } } ], "crossref": [ { "id": "A0A1D5P1V9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P1V9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040805", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040805", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16746", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16746", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859859", "url": "https://www.ncbi.nlm.nih.gov/gene/100859859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859859", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCCNSCF", "url": "https://omabrowser.org/oma/group/VCCNSCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1V9", "url": "https://www.orthodb.org/?gene=A0A1D5P1V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22663:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22663:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14634", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P1V9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIRVFCNSCFCEPRKATPRFIFTSCGHVICELCLQKGKKDECLICRTPCRTVFLSKETSPEIQSLFMGIDTLCKKYSKEITQISEFQEKNRKHLLAYHREKKVKLEESLRKARQQLHQIQSMKPPQQVTQLPFASTSRNPLSMPSRRLNGCSSYSLQPSHPSTSETMESMEVDHVPSPMRKPETMTGPVRLSVITPPQDGRMGSVSYRSSQSSGITSSQSTAVSTRSTPVGLPHNGCSLISPSGSQSSRRGSWSASDFRTPPLYQFTLPSPQSSVTRPPITISGILQRQYLGSASFGGQTAER", "length": 304, "header": "tr|A0A1D5P1V9-1|A0A1D5P1V9_CHICK Isoform 1 of Ring finger protein 212 OS=Gallus gallus OX=9031 GN=RNF212 PE=4 SV=3 CANONICAL=A0A1D5P1V9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9/entry", "sequence": { "sequence": "MAIRVFCNSCFCEPRKATPRFIFTSCGHVICELCLQKGKKDECLICRTPCRTVFLSKETSPEIQSLFMGIDTLCKKYSKEITQISEFQEKNRKHLLAYHREKKVKLEESLRKARQQLHQIQSMKPPQQVTQLPFASTSRNPLSMPSRRLNGCSSYSLQPSHPSTSETMESMEVDHVPSPMRKPETMTGPVRLSVITPPQDGRMGSVSYRSSQSSGITSSQSTAVSTRSTPVGLPHNGCSLISPSGSQSSRRGSWSASDFRTPPLYQFTLPSPQSSVTRPPITISGILQRQYLGSASFGGQTAER", "length": 304, "header": "tr|A0A1D5P1V9-1|A0A1D5P1V9_CHICK Isoform 1 of Ring finger protein 212 OS=Gallus gallus OX=9031 GN=RNF212 PE=4 SV=3 CANONICAL=A0A1D5P1V9-1" }, "locus": { "chromosome": "4", "start_pos": 84436956, "end_pos": 84419341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042767.1", "url": "https://www.ensembl.org/id/ENSGALT00010042767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025257.1", "url": "https://www.ensembl.org/id/ENSGALP00010025257.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859859", "name": "", "url": 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"MASWVFCNRCFQSPHRKSSFSLTSCGHVYCHSCLLKGTKNECVICQAPCQTVLLSKHTNSNIQTFFLGIDGLCKKYSQETSQISEFQEKHRRRLVAFYQEKISQLEESLRKSVLQIKQLQSMRSSQQPAFNKIKNSVSTKPNGYLFLPPNSSLPDRIESMDIDLTPPARKPEMSAGPSRISVISPPQDGRMGSVTCRGPQHLSLTPSHASMTKASRVPPLQMPYKELSPPPASQLSSRATQGPSPSVSSSWTGPPRQPISISGLLQRQCAGSASPRGMDTEKMSPFLPSTPTNLRSVASPWHACVHR", "length": 307 }, "evidence": [ { "id": "A0A1D5P1V9", "url": "https://omabrowser.org/oma/group/A0A1D5P1V9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q495C1-1", "protein_name": "Probable E3 SUMO-protein ligase RNF212", "gene_name": "RNF212", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANWVFCNRCFQPPHRTSCFSLTNCGHVYCDACLGKGKKNECLICKAPCRTVLLSKHTDADIQAFFMSIDSLCKKYSRETSQILEFQEKHRKRLLAFYREKISRLEESLRKSVLQIEQLQSMRSSQQTAFSTIKSSVSTKPHGCLLPPHSSAPDRLESMEVDLSPSPIRKSEIAAGPARISMISPPQDGRMGPHLTASFCFIPWLTLSKPPVPGECVISRGSPCFCIDVCPHWLLLLAFSSGRHGELTNSKTLPIYAEVQRAVLFPFQQAEGTLDTFRTPAVSVVFPLCQFERKKSF", "length": 297 }, "evidence": [ { "id": "A0A1D5P1V9", "url": "https://omabrowser.org/oma/group/A0A1D5P1V9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1V9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9" } ], "pmid": "" }, { "name": "SUMO transferase activity", "id": "GO:0019789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1V9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1V9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P1V9", 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"length": 1299, "header": "tr|A0A1D5P264-1|A0A1D5P264_CHICK Isoform 1 of RFX5 N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A1D5P264-1" }, "locus": { "chromosome": "10", "start_pos": 7778695, "end_pos": 7771160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056650.1", "url": "https://www.ensembl.org/id/ENSGALT00010056650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034392.1", "url": "https://www.ensembl.org/id/ENSGALP00010034392.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 793, "start_aa": "Thr", "end_pos": 793, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr793", "evidence": [ { "id": 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"GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 805, "start_aa": "Thr", "end_pos": 805, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr805", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", 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[ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6", "locus": { "chromosome": "8", "start_pos": 4527200, "end_pos": 4524436, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013609", "url": "https://www.ensembl.org/id/ENSGALG00010013609" } ] } } ], "crossref": [ { "id": "ENSGALG00000027608", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027608", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424387", "url": "https://www.ncbi.nlm.nih.gov/gene/424387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424387", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424387", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STSYHAF", "url": "https://omabrowser.org/oma/group/STSYHAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2C6", "url": "https://www.orthodb.org/?gene=A0A1D5P2C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12982", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12982", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12982:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12982:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015145912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCAQVETSPRRCWQKVLYERQPFPDNYVDQRFLEELRKNIHARQYQYWNVVYESGVVVQQLCSVCVFVVTWWYMDAGLLSPQGLFGAALLTSLLGYVLFDAIDAGVGRRESGRTRWADLKSTLVFTAFTYGFSPVLKTLTESISTDTIYAMSAFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFVMVTFAMQIFALWPMLQKKLKARTPCCYVGVTALFALVALVGLASVSSVGAVLFASLLLSISCLCPYCLIRLQQLKDNIHGPWDEAEIKEDLSRFLM", "length": 297, "header": "tr|A0A1D5P2C6-1|A0A1D5P2C6_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class C OS=Gallus gallus OX=9031 GN=PIGC PE=3 SV=1 CANONICAL=A0A1D5P2C6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6/entry", "sequence": { "sequence": "MVCAQVETSPRRCWQKVLYERQPFPDNYVDQRFLEELRKNIHARQYQYWNVVYESGVVVQQLCSVCVFVVTWWYMDAGLLSPQGLFGAALLTSLLGYVLFDAIDAGVGRRESGRTRWADLKSTLVFTAFTYGFSPVLKTLTESISTDTIYAMSAFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFVMVTFAMQIFALWPMLQKKLKARTPCCYVGVTALFALVALVGLASVSSVGAVLFASLLLSISCLCPYCLIRLQQLKDNIHGPWDEAEIKEDLSRFLM", "length": 297, "header": "tr|A0A1D5P2C6-1|A0A1D5P2C6_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class C OS=Gallus gallus OX=9031 GN=PIGC PE=3 SV=1 CANONICAL=A0A1D5P2C6-1" }, "locus": { "chromosome": "8", "start_pos": 4526059, "end_pos": 4525169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032692.1", "url": "https://www.ensembl.org/id/ENSGALT00010032692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019372.1", "url": "https://www.ensembl.org/id/ENSGALP00010019372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424387", "resource": "KEGG Pathway" }, { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2U8U156-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis class C, isoform C", "gene_name": "PIG-C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKNGQSKRQPWVKNLYSNREYPDNYTDASFLKDLRTNLHCRIYTFGEAIAGITVLNNQISCITGFLILYQLMLSDSVSPTTILVPSCGITGIGYLCYRGRSLSWALLGEDSKTLVTVVLFGYLFSPMLHTLTQAISTDTIYTMTFFVLLGNLIFGHYGLDVAMVSKAVSLNAAIFGAICLASRLPTSYHAFVLLVEAAVFFVLYPIMTEANWHAGFMLPIFAICCMALYCISRPVLYLYASTTIFINFVCPFIFVWQQQYKFNIHGPWDEAIVEENTEENLDGNLXRQLRFSEQLPPRLGSGDVEEHFTDR", "length": 312 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3GZK2-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "Pigc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCAQHLTDTTEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYARKYQYWAVVFESSVVVQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLIGYVLFDLIDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKAYTPRSYVGVTLLFAFSAFGGLLSISGVGAILFALLLISISCLCPYYLIRLQLFKENIHGPWDEAEIKEDLSRFLS", "length": 297 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O64761-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "PIGC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MESNLAGDSIPGPKWRKVAYGGMQIGYDDNYTDESFLEEMVMNANVVRRDLLKVMKDSVSISQYLCIVALVVLVWVHTLESSLDENSLLLLDLSLLASGFLILLLTEEKMLSLSLLLRYLVNISFFTTGLYILAPIYQTLTRSISSDSIWAVTVSLLLLHLFLHDYSGSTIRAPGALKTPNLTSCISVNASIVASVFVASRLPSRLHVFAVMLFSLQVFLFAPLVTYCIKKFNFGLHLLFSFALMGLTLYSIYALHRLFFLVFLSLVLLVNVVCPYWLIRMQEYKFEINGPWDEAKLCFDITD", "length": 303 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P46961-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit", "gene_name": "GPI2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTRSPWKRLLWLKQEYPDNYTDPSFIELRARQKAESNQKSDRKLSEAARAQIRLDFISFYQTILNTSFIYITFTYIYYYGFDPIPPTIFLSFITLIISRTKVDPLLSSFMDVKSSLIITFAMLTLSPVLKSLSKTTASDSIWTLSFWLTLWYIFVISSTKSKDKPSNLSTNILVALVAVLSSRLSTTIDVFCFLLICIQLNIILPTYLSVTNKVVPIISNIIVYSFLNVALGWIYMLLIFFASVFYITVLPKWFIYWKINYHKRDNDLLSTWDARTPILD", "length": 280 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3ZBX1-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "PIGC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCAQPVANTKEVRWQKVLYERQPFPDNYVDRRFLEELRKNIYARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLIGYVLFDFIDGGEGRKKSGRTRWADLKSALVFITFTYGFSPVLKTLTESVSTDTIYAMAVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKACTPRSYVGVTLLFAFSALGGLLSISAVGAILFALLLISISCLCPFYLIRLQLFKENIHGPWDEAEIKEDLSRFLS", "length": 297 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54M40-1", "protein_name": "Putative phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "pigC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNDHHLNHRIINNINASSSSSSSSSPVQTNININSANNTNNNNNNNNNNNNNNNNNNNNIDNKWKKNLYEKQPYSDNYTDETFLIGLVQNANFIKYDFWTVVLDSFTVSQQITSVILFAIIFFHSLKHTLTLPFLVAMAGGFLVLGYIAIIIIDPSANFLSIRSSFLHIILLFGTVYGLSPVLRTLTNSFSDDTIWALTFILLLAHLFFHDYGYTNNESQKFSAPVSLNAAIFASVLLGSRLPSNIHVFVLISYAIETFALFPIFRHHLKRHSMELHVGLTVILCVTCSLLLLGMSKLLALIYIGIIGTITFVCPLWLIFIQKYKNEINGPWDEASVISQSGGEF", "length": 345 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5PQQ4-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "Pigc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCAQHVADTSEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDLIDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKAYTPRSYVGVTLLFAFSAFGGLLSISGVGAILFALLLFSISCLCPYYLIHLQLFKENIHGPWDEAEIKEDLSRFLS", "length": 297 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92535-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "PIGC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYAQPVTNTKEVKWQKVLYERQPFPDNYVDRRFLEELRKNIHARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPHWLLGTGLASSLIGYVLFDLIDGGEGRKKSGQTRWADLKSALVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKACTPRSYVGVTLLFAFSAVGGLLSISAVGAVLFALLLMSISCLCPFYLIRLQLFKENIHGPWDEAEIKEDLSRFLS", "length": 297 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXR4-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C", "gene_name": "Pigc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAQRVTDTPEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDLIDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMAVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKAYTPRSYVGVTLLFAFSAFGGLLSISAVGAILFALLLFSISCLCPYYLIHLQLFKENIHGPWDEAEIKEDLSRFLS", "length": 297 }, "evidence": [ { "id": "A0A1D5P2C6", "url": "https://omabrowser.org/oma/group/A0A1D5P2C6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "id": "GO:0000506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000506", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P2D3-1", "uniprot_ac": "A0A1D5P2D3", "uniprot_id": "A0A1D5P2D3_CHICK", "mass": { "chemical_mass": 12824.0, "monoisotopic_mass": 12824.0 }, "refseq": { "ac": "XP_025003285", "name": "eukaryotic translation initiation factor 1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003285" }, "gene_names": [ { "name": "EIF1B", "type": "recommended", "evidence": [ { "id": "A0A1D5P2D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3" } ] }, { "name": "EIF1B", "type": "synonym", "evidence": [ { "id": "XP_025003285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003285" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 1B", "type": "synonym", "evidence": [ { "id": "A0A1D5P2D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 1b", "type": "synonym", "evidence": [ { "id": "XP_025003285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003285" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003285" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2D3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF1B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3", "locus": { "chromosome": "2", "start_pos": 43880927, "end_pos": 43891233, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016526", "url": "https://www.ensembl.org/id/ENSGALG00010016526" } ] } } ], "crossref": [ { "id": "A0A1D5P2D3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P2D3", "database": 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"A0A1D5P2D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSIQNLQSFDPFADATKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLLEIGIVKEEQLKVHGF", "length": 113, "header": "tr|A0A1D5P2D3-1|A0A1D5P2D3_CHICK Isoform 1 of Eukaryotic translation initiation factor 1B OS=Gallus gallus OX=9031 GN=EIF1B PE=1 SV=1 CANONICAL=A0A1D5P2D3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2D3/entry", "sequence": { "sequence": "MSSIQNLQSFDPFADATKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLLEIGIVKEEQLKVHGF", "length": 113, "header": "tr|A0A1D5P2D3-1|A0A1D5P2D3_CHICK Isoform 1 of Eukaryotic translation initiation factor 1B OS=Gallus gallus OX=9031 GN=EIF1B PE=1 SV=1 CANONICAL=A0A1D5P2D3-1" }, "locus": { "chromosome": "2", "start_pos": 43890899, "end_pos": 43887882, "strand": "+", "evidence": [ 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519010" } ] } ], "protein_names": [ { "name": "Disco interacting C", "type": "synonym", "evidence": [ { "id": "A0A1D5P2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8/entry#names_and_taxonomy" } ] }, { "name": "disco-interacting protein 2 homolog C isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040519010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519010" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040519010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519010" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2G8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIP2C", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8", "locus": { "chromosome": "2", "start_pos": 9911081, "end_pos": 10197538, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025554", "url": "https://www.ensembl.org/id/ENSGALG00010025554" } ] } } ], "crossref": [ { "id": "ENSGALG00000006652", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006652", 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040519010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040519010", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2G8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRSLESVSLPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPAANGAAAVRCRLQHSEGAARRMLRTANIGVCDIREAAARERAASTAGNRPLFYFRFGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1611, "header": "tr|A0A1D5P2G8-1|A0A1D5P2G8_CHICK Isoform 1 of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G8/entry", "sequence": { "sequence": "MADRSLESVSLPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPAANGAAAVRCRLQHSEGAARRMLRTANIGVCDIREAAARERAASTAGNRPLFYFRFGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1611, "header": "tr|A0A1D5P2G8-1|A0A1D5P2G8_CHICK Isoform 1 of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10197376, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062360.1", "url": "https://www.ensembl.org/id/ENSGALT00010062360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038552.1", "url": "https://www.ensembl.org/id/ENSGALP00010038552.1" } ] } }, { "isoform_ac": "A0A8V1A5P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P9/entry", "sequence": { "sequence": "MSSVTAQRFSLISGDITQKGYEKKRSKLIGAYLPQPPGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1540, "header": "tr|A0A8V1A5P9-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10102673, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062342.1", "url": "https://www.ensembl.org/id/ENSGALT00010062342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038537.1", "url": "https://www.ensembl.org/id/ENSGALP00010038537.1" } ] } }, { "isoform_ac": "A0A8V1A5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q5/entry", "sequence": { "sequence": "MLRTANIGVCDIREAAARERAASTAGNRPLFYFRFGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1538, "header": "tr|A0A8V1A5Q5-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10040345, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062347.1", "url": "https://www.ensembl.org/id/ENSGALT00010062347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038542.1", "url": "https://www.ensembl.org/id/ENSGALP00010038542.1" } ] } }, { "isoform_ac": "A0A8V1A5R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R0/entry", "sequence": { "sequence": "MTACCFRSSRAQRGSTWEHLYSFSLLFSVLQLSSEMGDITQKGYEKKRSKLIGAYLPQPPGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1563, "header": "tr|A0A8V1A5R0-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10175291, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062352.1", "url": "https://www.ensembl.org/id/ENSGALT00010062352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038547.1", "url": "https://www.ensembl.org/id/ENSGALP00010038547.1" } ] } }, { "isoform_ac": "A0A8V1A8A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8A5/entry", "sequence": { "sequence": "MAGRSRALCCSLPHLSDCDITQKGYEKKRSKLIGAYLPQPPGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1544, "header": "tr|A0A8V1A8A5-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10126497, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062351.1", "url": "https://www.ensembl.org/id/ENSGALT00010062351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038546.1", "url": "https://www.ensembl.org/id/ENSGALP00010038546.1" } ] } }, { "isoform_ac": "A0A8V1A8B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8B9/entry", "sequence": { "sequence": "MADRSLESVSLPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPAANGAAAVRCRLQHSEGAARRMLRTANIGVCDIREAAARERAASTAGNRPLFYFRFGVDQALPQERRTPVTPSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1601, "header": "tr|A0A8V1A8B9-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10197376, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062367.1", "url": "https://www.ensembl.org/id/ENSGALT00010062367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038556.1", "url": "https://www.ensembl.org/id/ENSGALP00010038556.1" } ] } }, { "isoform_ac": "A0A8V1AAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAW3/entry", "sequence": { "sequence": "MADRSLESVSLPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPGVDQALPQERRTPVTPSSSSRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTARVAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVTLVFPNNDPAAFMVAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCKTDEIGELCVCAIATGTSYYGLSGMTKNTFEVFPMTSSGGPITEYPFIRTGLLGFIGPGGLVFVIGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVSVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHVLYTLLNCRGTIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPPVLDTDDLPKKRPAQIYKPSNPETLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSLGCRVNLAICLQPHRLGKLAEQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSTHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSITECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1565, "header": "tr|A0A8V1AAW3-1|A0A1D5P2G8_CHICK Computationally mapped isoform of Disco interacting C OS=Gallus gallus OX=9031 GN=DIP2C PE=3 SV=1 CANONICAL=A0A1D5P2G8-1" }, "locus": { "chromosome": "2", "start_pos": 10197376, "end_pos": 9912085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062371.1", "url": "https://www.ensembl.org/id/ENSGALT00010062371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038559.1", "url": "https://www.ensembl.org/id/ENSGALP00010038559.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 123 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1436, "end_pos": 1438 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P2I8-1", "uniprot_ac": "A0A1D5P2I8", "uniprot_id": "A0A1D5P2I8_CHICK", "mass": { "chemical_mass": 9019.0, "monoisotopic_mass": 9019.0 }, "refseq": { "ac": "XP_004943858", "name": "cortexin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943858" }, "gene_names": [ { "name": "CTXN2", "type": "recommended", "evidence": [ { "id": "A0A1D5P2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8" } ] }, { "name": "CTXN2", "type": "synonym", "evidence": [ { "id": "XP_004943858", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943858" } ] } ], "protein_names": [ { "name": "Cortexin 2", "type": "synonym", "evidence": [ { "id": "A0A1D5P2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8/entry#names_and_taxonomy" } ] }, { "name": "cortexin-2", "type": "synonym", "evidence": [ { "id": "XP_004943858", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943858" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943858" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P2I8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTXN2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8", "locus": { "chromosome": "10", "start_pos": 10106371, "end_pos": 10098218, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018347", "url": "https://www.ensembl.org/id/ENSGALG00010018347" } ] } } ], "crossref": [ { "id": "ENSGALG00000038266", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859495", "url": "https://www.ncbi.nlm.nih.gov/gene/100859495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859495", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859495", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNDIMAH", "url": "https://omabrowser.org/oma/group/GNDIMAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2I8", "url": "https://www.orthodb.org/?gene=A0A1D5P2I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943858", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2I8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2I8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSSNYCGNTSASMSVNEMSAFPLTLEQKTGFAFVGILCVFLGLLIIRCFKILLDPYSSMPSSTWEDEVEGLDKGTFEYALA", "length": 82, "header": "tr|A0A1D5P2I8-1|A0A1D5P2I8_CHICK Isoform 1 of Cortexin 2 OS=Gallus gallus OX=9031 GN=CTXN2 PE=4 SV=2 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], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKU7-1", "protein_name": "Cortexin 2", "gene_name": "CTXN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSPYCGNSSAKMSVNEVSAFSLTMEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWENEVEEFDKGTFEYALA", "length": 81 }, "evidence": [ { "id": "A0A1D5P2I8", "url": "https://omabrowser.org/oma/group/A0A1D5P2I8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LSH9-1", "protein_name": "Cortexin-2", "gene_name": "Ctxn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMSSTYCSNSSAKMSVNEVSAFSLTLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYALA", "length": 82 }, "evidence": [ { "id": "A0A1D5P2I8", "url": "https://omabrowser.org/oma/group/A0A1D5P2I8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A1T4-1", "protein_name": "Cortexin 2", "gene_name": "Ctxn2", "tax_id": 10116, 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SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Apr 12, 2013 this sequence version replaced XP_001234983.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"header": "tr|A0A1D5P3M3-1|A0A1D5P3M3_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 13 OS=Gallus gallus OX=9031 GN=KCNK13 PE=3 SV=1 CANONICAL=A0A1D5P3M3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3M3/entry", "sequence": { "sequence": "MACGGCCCSGAGRLNADNARFLLLAVLIALYMLCGAAVFSAIELPGERRAKQRWEERLQNFTRRHNLSRAELRDFLREYEEASVAGIRVDDIRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLIGCAGTILFFNLFLERLITVIAYVMKSCHERQLRRKGVLPHDGRRGSGTSEADSLAGWKPSVYYVMLILCIASLIISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNTHYESQGLYRFGNFVFILMGVCCIYSLFNVISIVIKQSINWILKKLDCRCCHRCQRKLFRSRRNVVMPGNVRGRRNISIETDIVNESDTDGRRLSGEMISMKDFLASNKVSLAIMQKQLSETANGYPRQMSSKQNGFSGGVGALAIMNNRLAETSVDR", "length": 407, "header": "tr|A0A1D5P3M3-1|A0A1D5P3M3_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 13 OS=Gallus gallus OX=9031 GN=KCNK13 PE=3 SV=1 CANONICAL=A0A1D5P3M3-1" }, "locus": { "chromosome": "5", "start_pos": 43290259, "end_pos": 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"monoisotopic_mass": 22154.0 }, "refseq": { "ac": "XP_424392", "name": "TM2 domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424392" }, "gene_names": [ { "name": "TM2D2", "type": "recommended", "evidence": [ { "id": "A0A1D5P3V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1" } ] }, { "name": "TM2D2", "type": "synonym", "evidence": [ { "id": "XP_424392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424392" } ] } ], "protein_names": [ { "name": "TM2 domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A1D5P3V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1/entry#names_and_taxonomy" } ] }, { "name": "TM2 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_424392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3V1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TM2D2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1", "locus": { "chromosome": "22", "start_pos": 2590476, "end_pos": 2592249, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017550", "url": "https://www.ensembl.org/id/ENSGALG00010017550" } ] } } ], "crossref": [ { "id": "A0A1D5P3V1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P3V1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003356", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426780", "url": "https://www.ncbi.nlm.nih.gov/gene/426780", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426780", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426780", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIDHKGN", "url": "https://omabrowser.org/oma/group/PIDHKGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3V1", "url": "https://www.orthodb.org/?gene=A0A1D5P3V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21016:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21016:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P3V1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRRGGSLGYALLCGQAVLLLGNLLLLHGASRGLPHNGSEPEAPGSEPAAATWAYSDPRAPLVLCTYLPEEFVECDEPVDHGGNATAQQELGHGCVKFGGQAHGDVDHTRVQCRALDGIECAEPRSFLRGSRPCVRYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", "length": 207, "header": "tr|A0A1D5P3V1-1|A0A1D5P3V1_CHICK Isoform 1 of TM2 domain-containing protein 2 OS=Gallus gallus OX=9031 GN=TM2D2 PE=3 SV=2 CANONICAL=A0A1D5P3V1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1/entry", "sequence": { "sequence": "MAPRRGGSLGYALLCGQAVLLLGNLLLLHGASRGLPHNGSEPEAPGSEPAAATWAYSDPRAPLVLCTYLPEEFVECDEPVDHGGNATAQQELGHGCVKFGGQAHGDVDHTRVQCRALDGIECAEPRSFLRGSRPCVRYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", "length": 207, "header": "tr|A0A1D5P3V1-1|A0A1D5P3V1_CHICK Isoform 1 of TM2 domain-containing protein 2 OS=Gallus gallus OX=9031 GN=TM2D2 PE=3 SV=2 CANONICAL=A0A1D5P3V1-1" }, "locus": { "chromosome": "22", "start_pos": 2592178, "end_pos": 2591281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042424.1", "url": "https://www.ensembl.org/id/ENSGALT00010042424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024914.1", "url": "https://www.ensembl.org/id/ENSGALP00010024914.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426780", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426780", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H1K7-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "Tm2d2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDLTPSGAAHPEGPVAPSWEYSDPHSPVILCSYLPDEFVDCDAPVDHVGNATASQELGYGCLKFGGQAYSDVEHTAVQCRALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", "length": 213 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LTJ8-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "TM2D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSHNTTAEPEFTTAGAAQLEGSTGALSWEYGDPQSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCRALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", "length": 214 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TA35-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "TM2D2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLGGYPVSYLLLCGQAALLLGNLLLLHCVSRSHSHNATAEPELTSAGAAHPEGSPGAASWEYGDPHSPVILCSYLPDEFIECEDPVDHVGNTTAFQELGYGCLKFGGQAYRDVEHTRVQCRALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTIY", "length": 214 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q566R2-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "Tm2d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDLTPSGAAHLEGPAASSWEYSDPNSPVILCSYLPDEFVDCDAPVDHVGNATAYQELGYGCLKFGGQAYSDVEHTAVQCRALEGIECASPRTFLRKNKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", "length": 213 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DHN3-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "tm2d2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQISVNYILLCGQFLLFFTVLLLQCLEGIHSQNSTEPPGNRVTTSKPVLFSEQPEENVTESGSVIPTETSNHTEQYEYNPPSPVVLCRYLPEEFIFCQDPVDHGGNVSAFQELGYGCVKFGGQVYKDVNHTQVLCTALDGIECAGPREFLRGNEPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLTPSDSSNWCTFY", "length": 229 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R0I4-1", "protein_name": "TM2 domain-containing protein 2", "gene_name": "Tm2d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDLTPSGAAHLEGPAASSWEYSDPNSPVILCSYLPDEFVDCDAPVDHVGNATASQELGYGCLKFGGQAYSDVQHTAVQCRALEGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY", 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"MRIFYGLLAFLVARQHDAQAIQARSDKEQPQTVVSGTAVQSVVPVQAQLGSGMGPSSSSSSASSASGGAGNSAFYPLGPNVMCSFLPRDFLDCKDPVDHRENATAQQEKKYGCLKFGGSTYEEVEHAMVWCTVFADIECYGNRTFLRAGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKLLTMGGVGVWWIIDVILLITNNLLPEDGSNWNPYV", "length": 224 }, "evidence": [ { "id": "A0A1D5P3V1", "url": "https://omabrowser.org/oma/group/A0A1D5P3V1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P3V1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P3V1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 207, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P3V1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P3V1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P3V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3V1" }, { "id": "PF05154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM2", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 188, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P406-1", "uniprot_ac": "A0A1D5P406", "uniprot_id": "A0A1D5P406_CHICK", "mass": { "chemical_mass": 23434.0, "monoisotopic_mass": 23434.0 }, "refseq": { "ac": "NP_001264524", "name": "Fanconi anemia core complex-associated protein 24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" }, "gene_names": [ { "name": "FAAP24", "type": "recommended", "evidence": [ { "id": "A0A1D5P406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ] }, { "name": "C11H19ORF40", "type": "synonym", "evidence": [ { "id": "NP_001264524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] }, { "name": "C19orf40", "type": "synonym", "evidence": [ { "id": "NP_001264524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] }, { "name": "FAAP24", "type": "synonym", "evidence": [ { "id": "NP_001264524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] } ], "protein_names": [ { "name": "Fanconi anemia core complex associated protein 24", "type": "synonym", "evidence": [ { "id": "A0A1D5P406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia core complex-associated protein 24", "type": "synonym", "evidence": [ { "id": "NP_001264524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] }, { "name": "Fanconi anemia-associated protein of 24 kDa", "type": "synonym", "evidence": [ { "id": "NP_001264524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX933739.2, HAEL01006563.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU383704.1, BX933739.2 and JAENSK010000248.1. On Apr 12, 2013 this sequence version replaced XP_414132.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains to make the sequence consistent with the transcript data. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAAP24", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406", "locus": { "chromosome": "11", "start_pos": 9637751, "end_pos": 9619209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024868", "url": "https://www.ensembl.org/id/ENSGALG00010024868" } ] } } ], "crossref": [ { "id": "A0A1D5P406", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P406", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034534", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034534", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415770", "url": "https://www.ncbi.nlm.nih.gov/gene/415770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415770", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPVHVPF", "url": "https://omabrowser.org/oma/group/GPVHVPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P406", "url": "https://www.orthodb.org/?gene=A0A1D5P406", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31786", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31786", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31786:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31786:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17949", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17949", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P406-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKGDVPAAAGSVVVPYGHVVGNEKWRGSEVARRLQGKTKLIFEDGLGLVDFHLSNRICVLYISEADLVAGDEFKRRVVRFRNASSLGGIVIVEKTPITEQYFSAVQKLVVLQLGMVLLPVANQGEASQLITQLVREQSKDHTSNPFLRKQCSQLAEASVFRTVQQIPGVGKTKALLLLQQFGSIHQICNASVKELELVVGQTVAQQIHTFLGS", "length": 215, "header": "tr|A0A1D5P406-1|A0A1D5P406_CHICK Isoform 1 of Fanconi anemia core complex associated protein 24 OS=Gallus gallus OX=9031 GN=FAAP24 PE=4 SV=1 CANONICAL=A0A1D5P406-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P406-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406/entry", "sequence": { "sequence": "MAAKGDVPAAAGSVVVPYGHVVGNEKWRGSEVARRLQGKTKLIFEDGLGLVDFHLSNRICVLYISEADLVAGDEFKRRVVRFRNASSLGGIVIVEKTPITEQYFSAVQKLVVLQLGMVLLPVANQGEASQLITQLVREQSKDHTSNPFLRKQCSQLAEASVFRTVQQIPGVGKTKALLLLQQFGSIHQICNASVKELELVVGQTVAQQIHTFLGS", "length": 215, "header": "tr|A0A1D5P406-1|A0A1D5P406_CHICK Isoform 1 of Fanconi anemia core complex associated protein 24 OS=Gallus gallus OX=9031 GN=FAAP24 PE=4 SV=1 CANONICAL=A0A1D5P406-1" }, "locus": { "chromosome": "11", "start_pos": 9629875, "end_pos": 9627945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060718.1", "url": "https://www.ensembl.org/id/ENSGALT00010060718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037477.1", "url": "https://www.ensembl.org/id/ENSGALP00010037477.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415770", "resource": "KEGG Pathway" }, { "id": "R-GGA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-GGA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TS87-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGNAPDGTGPVHVPFGHIVANEKWRGSQLAQGMQGKIKLIFEDGLTPVDFYLPSRSCILYITEADLVAGNGYRKRLVRVRNSTKLQAIVVVEKTQMSEQYFPAAQKFTVLDLGMVLLPVANQIEAACLITQLVQEQTKEPSKNPVLRRKRAVISEPALLRTVQRIPGVGKVKAPLLLQRFPSIQQLSNASVQELEPVVGQAVARHVHAFFTQPR", "length": 215 }, "evidence": [ { "id": "A0A1D5P406", "url": "https://omabrowser.org/oma/group/A0A1D5P406/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZE71-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "Faap24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERNPPGGTGPVHVPLGHIVANEKWRGSQLAQELQGKVRLIFEEGLASTDFYLSSKSCILYITEADLVAGHGYKKRLARFRNSAHLQGIVIVEKTQMSEQYFPAAQKFTVLDLGMVLLPVASQSEASCLIFQLVQEQTREPSKNPFLRKKRSMLSESSLVQTVQQIPGVGKVKAPLLLQKFPSIQQLSNASTQELEEVVGRTVAQQIHTFFTQPKRQQSWH", "length": 221 }, "evidence": [ { "id": "A0A1D5P406", "url": "https://omabrowser.org/oma/group/A0A1D5P406/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHY5-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESNPPDSTGPMHVPFGHIVANEKWRGSQLAQGMQGKIKLVFEDGLTPVDFYLSSKSCILYITEAELVAGNGYRKRLVRVRNSNKLQGIVVVEKTQMSEQYFPAVQKFTVLDLGMVLLPVASQMEASCLIIQLVQEQTREPSKNPFLRKKRALVSEPALLRSVQQIPGVGKVKAPLLLQRFPSIQQLSNASLRELEAVVGPAAAQRIHAFFSQPR", "length": 215 }, "evidence": [ { "id": "A0A1D5P406", "url": "https://omabrowser.org/oma/group/A0A1D5P406/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHL6-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "Faap24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNPPDGTGPVHVPLGHIVASEKWRGSQLAQEMQGKVRLIFEEGLASADFYLSSKSCILYVTEADLVAGHGYRKRLARFRNSSHLQGIIIVEKTQMSEQYFPAVQKFTVLDLGMVLLPVASQSEASCLIIHLVQEQTREPSKNPFLRKKRSMLSELSLVQTVQQIPGVGKVKAPLLLQKFPSIQQLSNASVQELEEVVGPAAAQQIHTFFTQPKRQQPRS", "length": 221 }, "evidence": [ { "id": "A0A1D5P406", "url": "https://omabrowser.org/oma/group/A0A1D5P406/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTP7-1", "protein_name": "Fanconi anemia core complex-associated protein 24", "gene_name": "FAAP24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR", "length": 215 }, "evidence": [ { "id": "A0A1D5P406", "url": "https://omabrowser.org/oma/group/A0A1D5P406/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P406", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P406-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 215, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P406-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P406" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" }, { "id": "PF17949", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17949" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fanconi anemia core complex-associated protein 24 pseudonuclease", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 136, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5P406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P406" }, { "id": "PF14520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-like helix-hairpin-helix tandem", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 210, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1I7Q410-1", "uniprot_ac": "A0A1I7Q410", "uniprot_id": "A0A1I7Q410_CHICK", "mass": { "chemical_mass": 84668.0, "monoisotopic_mass": 84668.0 }, "refseq": { "ac": "XP_015131672", "name": "integrator complex subunit 10 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131672" }, "gene_names": [ { "name": "INTS10", "type": "recommended", "evidence": [ { "id": "A0A1I7Q410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410" } ] }, { "name": "INTS10", "type": "synonym", "evidence": [ { "id": "XP_015131672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131672" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 10", "type": "recommended", "evidence": [ { "id": "A0A1I7Q410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015131672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131672" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131672" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1I7Q410", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS10", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410", "locus": { "chromosome": "4", "start_pos": 33723359, "end_pos": 33704731, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007784", "url": "https://www.ensembl.org/id/ENSGALG00010007784" } ] } } ], "crossref": [ { "id": "A0A1I7Q410", "url": "https://alphafold.ebi.ac.uk/entry/A0A1I7Q410", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010130", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010130", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422489", "url": "https://www.ncbi.nlm.nih.gov/gene/422489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1I7Q410", "url": "https://www.orthodb.org/?gene=A0A1I7Q410", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UD16", "url": "https://www.orthodb.org/?gene=A0A3Q2UD16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTY4", "url": "https://www.orthodb.org/?gene=A0A8V0XTY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XU03", "url": "https://www.orthodb.org/?gene=A0A8V0XU03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVX1", "url": "https://www.orthodb.org/?gene=A0A8V0XVX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVY1", "url": "https://www.orthodb.org/?gene=A0A8V0XVY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16055:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16055:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015131672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131672", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1I7Q410", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1I7Q410-1", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UD16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UD16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XU03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XU03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKTSSPPMGLLQQEFIPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 736, "header": "tr|A0A1I7Q410-1|A0A1I7Q410_CHICK Isoform 1 of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=2 CANONICAL=A0A1I7Q410-1" }, "isoforms": [ { "isoform_ac": "A0A1I7Q410-1", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410/entry", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKTSSPPMGLLQQEFIPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 736, "header": "tr|A0A1I7Q410-1|A0A1I7Q410_CHICK Isoform 1 of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=2 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33723134, "end_pos": 33704788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018548.1", "url": "https://www.ensembl.org/id/ENSGALT00010018548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010152.1", "url": "https://www.ensembl.org/id/ENSGALP00010010152.1" } ] } }, { "isoform_ac": "A0A3Q2UD16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD16/entry", "sequence": { "sequence": "MCMHTDVHASCVVRQGEPASSFLHCCSRFFSVSVIHYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 703, "header": "tr|A0A3Q2UD16-1|A0A3Q2UD16_CHICK Computationally mapped isoform of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=1 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33723134, "end_pos": 33705235, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018544.1", "url": "https://www.ensembl.org/id/ENSGALT00010018544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010150.1", "url": "https://www.ensembl.org/id/ENSGALP00010010150.1" } ] } }, { "isoform_ac": "A0A8V0XTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY4/entry", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKTSSPPMGLLQQEFIPVLQPSIQTADRYQVEKPHS", "length": 693, "header": "tr|A0A8V0XTY4-1|A0A1I7Q410_CHICK Computationally mapped isoform of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=1 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33721274, "end_pos": 33704788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018527.1", "url": "https://www.ensembl.org/id/ENSGALT00010018527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010137.1", "url": "https://www.ensembl.org/id/ENSGALP00010010137.1" } ] } }, { "isoform_ac": "A0A8V0XU03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU03/entry", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMYVTQGGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 681, "header": "tr|A0A8V0XU03-1|A0A1I7Q410_CHICK Computationally mapped isoform of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=1 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33723134, "end_pos": 33704788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018560.1", "url": "https://www.ensembl.org/id/ENSGALT00010018560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010158.1", "url": "https://www.ensembl.org/id/ENSGALP00010010158.1" } ] } }, { "isoform_ac": "A0A8V0XVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVX1/entry", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKTSSPPMGLLQQEFIPVLQPSIQTADSLAQASDLLL", "length": 694, "header": "tr|A0A8V0XVX1-1|A0A1I7Q410_CHICK Computationally mapped isoform of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=1 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33722864, "end_pos": 33704788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018537.1", "url": "https://www.ensembl.org/id/ENSGALT00010018537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010145.1", "url": "https://www.ensembl.org/id/ENSGALP00010010145.1" } ] } }, { "isoform_ac": "A0A8V0XVY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY1/entry", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 659, "header": "tr|A0A8V0XVY1-1|A0A1I7Q410_CHICK Computationally mapped isoform of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=3 SV=1 CANONICAL=A0A1I7Q410-1" }, "locus": { "chromosome": "4", "start_pos": 33723134, "end_pos": 33704788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018555.1", "url": "https://www.ensembl.org/id/ENSGALT00010018555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010156.1", "url": "https://www.ensembl.org/id/ENSGALP00010010156.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 690, "start_aa": "Thr", "end_pos": 690, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr690", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "A0A1I7Q410", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A1I7Q410", "url": "https://www.uniprot.org/uniprotkb/A0A1I7Q410" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A1I7Q410", "url": 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##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154365" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCND3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4", "locus": { "chromosome": "26", "start_pos": 3337930, "end_pos": 3431437, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027277", "url": "https://www.ensembl.org/id/ENSGALG00010027277" } ] } } ], "crossref": [ { "id": "A0A1D5P8P4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8P4", "database": 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OS=Gallus gallus OX=9031 GN=KCND3 PE=4 SV=1 CANONICAL=A0A1D5P8P4-1" }, "locus": { "chromosome": "26", "start_pos": 3426649, "end_pos": 3338715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066134.1", "url": "https://www.ensembl.org/id/ENSGALT00010066134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040400.1", "url": "https://www.ensembl.org/id/ENSGALP00010040400.1" } ] } }, { "isoform_ac": "A0A8V1AAZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAZ1/entry", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPTEKNKRQDELIILNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCILNFYRTGKLHYPRYECISAYDEELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQEGSMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGNKELPCGERYAVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTNHEFIDEQLFEQNCMESSMQNYPSSRSPSLSSHHGLTTSCCSRRHKKTTHLPNSSVPATRLRSMQELSTIHIQCSEQPSLTTSRSSLNMKSDDGLRPNCKAAQITTAIISIPTPPALTPEGESRPPPSSPGHSTNISTTTTSNIVKVSAL", "length": 608, "header": "tr|A0A8V1AAZ1-1|A0A1D5P8P4_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily D member 3 OS=Gallus gallus OX=9031 GN=KCND3 PE=4 SV=1 CANONICAL=A0A1D5P8P4-1" }, "locus": { "chromosome": "26", "start_pos": 3426649, "end_pos": 3338715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066141.1", "url": "https://www.ensembl.org/id/ENSGALT00010066141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040407.1", "url": "https://www.ensembl.org/id/ENSGALP00010040407.1" } ] } }, { "isoform_ac": "F1NRL8-1", "url": "https://www.uniprot.org/uniprotkb/F1NRL8/entry", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPTEKNKRQDELIILNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCILNFYRTGKLHYPRYECISAYDEELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQEGSMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGNKELPCGERYAVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGSTEDEQHTTKGTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQLFEQNCMESSMQNYPSSRSPSLSSHHGLTTSCCSRRHKKTTHLPNSSVPATRLRSMQELSTIHIQCSEQPSLTTSRSSLNMKSDDGLRPNCKAAQITTAIISIPTPPALTPEGESRPPPSSPGHSTNISTTTTSNIVKVSAL", "length": 658, "header": "tr|F1NRL8-1|A0A1D5P8P4_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily D member 3 OS=Gallus gallus OX=9031 GN=KCND3 PE=4 SV=1 CANONICAL=A0A1D5P8P4-1" }, "locus": { "chromosome": "26", "start_pos": 3426649, "end_pos": 3338715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066138.1", "url": "https://www.ensembl.org/id/ENSGALT00010066138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040404.1", "url": "https://www.ensembl.org/id/ENSGALP00010040404.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374228", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374228", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" }, { "id": "R-GGA-5576894", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576894", "resource": "Reactome", "description": "Phase 1 - inactivation of fast Na+ channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T6A8-1", "protein_name": "Potassium voltage-gated channel subfamily D member 3", "gene_name": "KCND3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELLGTPEEENMGKTTSLIESQHHHLLHCLEKTTNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL", "length": 636 }, "evidence": [ { "id": "A0A1D5P8P4", "url": "https://omabrowser.org/oma/group/A0A1D5P8P4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62897-1", "protein_name": "A-type voltage-gated potassium channel KCND3", "gene_name": "Kcnd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNESENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHSGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSITSNVVKVSVL", "length": 655 }, "evidence": [ { "id": "A0A1D5P8P4", "url": "https://omabrowser.org/oma/group/A0A1D5P8P4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UK17-1", "protein_name": "A-type voltage-gated potassium channel KCND3", "gene_name": "KCND3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL", "length": 655 }, "evidence": [ { "id": "A0A1D5P8P4", "url": "https://omabrowser.org/oma/group/A0A1D5P8P4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z0V1-1", "protein_name": "A-type voltage-gated potassium channel KCND3", "gene_name": "Kcnd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEQMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHSGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTLHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSITSNVVKVSAL", "length": 655 }, "evidence": [ { "id": "A0A1D5P8P4", "url": "https://omabrowser.org/oma/group/A0A1D5P8P4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "postsynaptic specialization membrane", "id": "GO:0099634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization", "id": "GO:1902282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902282", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "A-type (transient outward) potassium channel activity", "id": "GO:0005250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005250", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "regulation of heart rate by cardiac conduction", "id": "GO:0086091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" }, { "name": "potassium ion export across plasma membrane", "id": "GO:0097623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097623", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8P4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"A0A1D5PQQ6_CHICK", "mass": { "chemical_mass": 33179.0, "monoisotopic_mass": 33179.0 }, "refseq": { "ac": "XP_024999390", "name": "mitochondrial import receptor subunit TOM40B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999390" }, "gene_names": [ { "name": "TOMM40L", "type": "recommended", "evidence": [ { "id": "A0A1D5PQQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ] }, { "name": "TOMM40L", "type": "synonym", "evidence": [ { "id": "XP_024999390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999390" } ] } ], "protein_names": [ { "name": "Translocase of outer mitochondrial membrane 40 like", "type": "synonym", "evidence": [ { "id": "A0A1D5PQQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import receptor subunit TOM40B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024999390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999390" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOMM40L", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6", "locus": {} } ], "crossref": [ { "id": "A0A1D5PQQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038400", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038400", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07305", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07305", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426278", "url": "https://www.ncbi.nlm.nih.gov/gene/426278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WTEMGNT", "url": "https://omabrowser.org/oma/group/WTEMGNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQQ6", "url": "https://www.orthodb.org/?gene=A0A1D5PQQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9F4", "url": "https://www.orthodb.org/?gene=A0A8V1A9F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC59", "url": "https://www.orthodb.org/?gene=A0A8V1AC59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AET8", "url": "https://www.orthodb.org/?gene=A0A8V1AET8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10802", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10802", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999390", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC59", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AET8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNAWGPAAPRAPRRGENLGNPGSFDELHRQCKEVFPQQMEGVKLIVNKALSSHFQVTHTVHMSTLGPSNYHFNATFVGDRQLGPTEAFPTLVGDMDNSGSLNAQILHLLAERIRTKAVFQTHQAKFVTWQFDGEYRGDDCTATLTLGNPDLLGGSVILVAHFLQSVTPRLVLGGEMVYHRRPGEEGAILTLAGKYTASNWVATLNVGYGGAHASYYHKANEQVQVGVELEANTRLQDTTFAFGYQLNLPQANVVFRGLLDSNWSVGAVLEKKLPPLPVTLALGAFLNHWKNRFHCGFSVIVG", "length": 303, "header": "tr|A0A1D5PQQ6-1|A0A1D5PQQ6_CHICK Isoform 1 of Translocase of outer mitochondrial membrane 40 like OS=Gallus gallus OX=9031 GN=TOMM40L PE=1 SV=2 CANONICAL=A0A1D5PQQ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6/entry", "sequence": { "sequence": "MGNAWGPAAPRAPRRGENLGNPGSFDELHRQCKEVFPQQMEGVKLIVNKALSSHFQVTHTVHMSTLGPSNYHFNATFVGDRQLGPTEAFPTLVGDMDNSGSLNAQILHLLAERIRTKAVFQTHQAKFVTWQFDGEYRGDDCTATLTLGNPDLLGGSVILVAHFLQSVTPRLVLGGEMVYHRRPGEEGAILTLAGKYTASNWVATLNVGYGGAHASYYHKANEQVQVGVELEANTRLQDTTFAFGYQLNLPQANVVFRGLLDSNWSVGAVLEKKLPPLPVTLALGAFLNHWKNRFHCGFSVIVG", "length": 303, "header": "tr|A0A1D5PQQ6-1|A0A1D5PQQ6_CHICK Isoform 1 of Translocase of outer mitochondrial membrane 40 like OS=Gallus gallus OX=9031 GN=TOMM40L PE=1 SV=2 CANONICAL=A0A1D5PQQ6-1" }, "locus": { "chromosome": "25", "start_pos": 2497481, "end_pos": 2494422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066668.1", "url": "https://www.ensembl.org/id/ENSGALT00010066668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040816.1", "url": "https://www.ensembl.org/id/ENSGALP00010040816.1" } ] } }, { "isoform_ac": "A0A8V1A9F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9F4/entry", "sequence": { "sequence": "MGNAWGPAAPRAPRRGENLGNPGSFDELHRQCKEVFPQQMEGVKLIVNKALSSHFQVTHTVHMSTLGPSNYHFNATFVGDRQLGPTEAFPTLVGDMDNSGSLNAQILHLLAERIRTKAVFQTHQAKFVTWQFDGEYRGDDCTATLTLGNPDLLGGSVILVAHFLQSVTPRLVLGGEMVYHRRPGEEGAILTLAGKYTASNWVATLNVGYGGAHASYYHKANEQVQVGVELEANTRLQDTTFAFGYQLNLPQANVVFRGLLDSNWSVGAVLEKKLPPLPVTLALGAFLNHWKNRSHRATGEPVTCPRATRHLPHSR", "length": 315, "header": "tr|A0A8V1A9F4-1|A0A1D5PQQ6_CHICK Computationally mapped isoform of Translocase of outer mitochondrial membrane 40 like OS=Gallus gallus OX=9031 GN=TOMM40L PE=1 SV=1 CANONICAL=A0A1D5PQQ6-1" }, "locus": { "chromosome": "25", "start_pos": 2497481, "end_pos": 2494322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066664.1", "url": "https://www.ensembl.org/id/ENSGALT00010066664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040813.1", "url": "https://www.ensembl.org/id/ENSGALP00010040813.1" } ] } }, { "isoform_ac": "A0A8V1AC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC59/entry", "sequence": { "sequence": "MGNAWGPAAPRAPRRGENLGNPGSFDELHRQCKEVFPQQMEGVKLIVNKALSSHFQVTHTVHMSTLGPSNYHFNATFVGDRQLGPTEAFPTLVGDMDNSGSLNAQILHLLAERIRTKAVFQTHQAKFVTWQFDGEYRGDDCTATLTLGNPDLLGGSVILVAHFLQSVTPRLVLGGEMVYHRRPGEEGAILTLAGKYTGMGAAGHGDTTLSPGMSPRPSICFFSSSFQLGGDAQCRLWWCPCELLPQSQRAGAGRGGAGGQHAAAGHHLRLWLPAQPAAGQRRLQRAPGQ", "length": 289, "header": "tr|A0A8V1AC59-1|A0A1D5PQQ6_CHICK Computationally mapped isoform of Translocase of outer mitochondrial membrane 40 like OS=Gallus gallus OX=9031 GN=TOMM40L PE=1 SV=1 CANONICAL=A0A1D5PQQ6-1" }, "locus": { "chromosome": "25", "start_pos": 2497481, "end_pos": 2494546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066667.1", "url": "https://www.ensembl.org/id/ENSGALT00010066667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040815.1", "url": "https://www.ensembl.org/id/ENSGALP00010040815.1" } ] } }, { "isoform_ac": "A0A8V1AET8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AET8/entry", "sequence": { "sequence": "MGNAWGPAAPRAPRRGENLGNPGSFDELHRQCKEVFPQQMEGVKLIVNKALSSHFQVTHTVHMSTLGPSNYHFNATFVGDRQLGPTEAFPTLVGDMDNSGSLNAQILHLLAERIRTKAVFQTHQAKFVTWQFDGEYRGDDCTATLTLGNPDLLGGDPGGTFPSERHPPPGVGWGDGLPPAAGGGRSHPDTGRQIHGFQLGGDAQCRLWWCPCELLPQSQRAGEHRGPLCAVQQWGAGMVGLEEVLRAGEVWGHSVVGLEGVSKTTEVWGHGVVGLEGISKTTKVWGHGVVGLEEIPNTIELWGHSVVVLEGISKTT", "length": 316, "header": "tr|A0A8V1AET8-1|A0A1D5PQQ6_CHICK Computationally mapped isoform of Translocase of outer mitochondrial membrane 40 like OS=Gallus gallus OX=9031 GN=TOMM40L PE=1 SV=1 CANONICAL=A0A1D5PQQ6-1" }, "locus": { "chromosome": "25", "start_pos": 2497481, "end_pos": 2495313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066666.1", "url": "https://www.ensembl.org/id/ENSGALT00010066666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040814.1", "url": "https://www.ensembl.org/id/ENSGALP00010040814.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1IS56-1", "protein_name": "Translocase of outer mitochondrial membrane 40 like", "gene_name": "TOMM40L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNTLGLAPMGALPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAGHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4F267-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "gene_name": "Tomm40l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNTLGLAPMGTLPRWSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSALHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6QR22-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "gene_name": "TOMM40L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNTLGLAPMGALPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSGGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIVVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HTY8-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "gene_name": "Tomm40l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGNTLGLAPMGTLSRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAIFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSVTHRLVLGGELVYHRRPGEEGAILTLAGKYSALHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q969M1-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "gene_name": "TOMM40L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZR3-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "gene_name": "Tomm40l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNTLGLAPMGTLPRRSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG", "length": 308 }, "evidence": [ { "id": "A0A1D5PQQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PQQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ], "pmid": "" }, { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 86 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 263, "end_pos": 265 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PV94-1", "uniprot_ac": "A0A1D5PV94", "uniprot_id": "A0A1D5PV94_CHICK", "mass": { "chemical_mass": 70423.0, "monoisotopic_mass": 70423.0 }, "refseq": {}, "gene_names": [ { "name": "MBTD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PV94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ] } ], "protein_names": [ { "name": "Mbt domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PV94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MBTD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94", "locus": { "chromosome": "18", "start_pos": 5695405, "end_pos": 5721477, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029226", "url": "https://www.ensembl.org/id/ENSGALG00010029226" } ] } } ], "crossref": [ { "id": "A0A1D5PV94", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PV94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002954", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20120", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20120", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20123", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20123", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20129", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20129", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417387", "url": "https://www.ncbi.nlm.nih.gov/gene/417387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P5H2", "url": "https://www.orthodb.org/?gene=A0A1D5P5H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PV94", "url": "https://www.orthodb.org/?gene=A0A1D5PV94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIV3", "url": "https://www.orthodb.org/?gene=A0A8V1AIV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKY8", "url": "https://www.orthodb.org/?gene=A0A8V1AKY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P5H2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PV94-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFDGYDSCSEDTSSSSSSDESEEEVSPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVPVEGFSWGSYINSNSFTAAPVTCFKHAPMGTCWGDISEGVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSNLDFWCNVCGSDIHPVGWCATSGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFRTSMRVEVVDKTHLCRTRVAVVENVIGGRLRLVYEESEDKTDDFWCHMYSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDAPSHLFLKVKEVDTAGEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETDSIAAPVKLFNKEVPNHGFHVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESPDLYPVGWCQLTGYQLQPPAPQSSRDNQSSSSKQKKKSKSQQYKGHKKMTSLQLKEELLDGEEYSFLQGASDQESNGSASYYIKQEP", "length": 628, "header": "tr|A0A1D5PV94-1|A0A1D5PV94_CHICK Isoform 1 of Mbt domain containing 1 OS=Gallus gallus OX=9031 GN=MBTD1 PE=4 SV=1 CANONICAL=A0A1D5PV94-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5H2/entry", "sequence": { "sequence": "MHHSLVSTNAVSTWAEKNLIDVYYQNRNVLICSSKIPAKTEHLSQTERKRRDSFGMFDGYDSCSEDTSSSSSSDESEEEVSPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQVAGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVPVEGFSWGSYINSNSFTAAPVTCFKHAPMGTCWGDISEGVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSNLDFWCNVCGSDIHPVGWCATSGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFRTSMRVEVVDKTHLCRTRVAVVENVIGGRLRLVYEESEDKTDDFWCHMYSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDAPSHLFLKVKEVDTAGEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETDSIAAPVKLFNKEVPNHGFHVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESPDLYPVGWCQLTGYQLQPPAPQSSRDNQSSSSKQKKKSKSQQYKGHKKMTSLQLKEELLDGEEYSFLQGASDQESNGSASYYIKQEP", "length": 685, "header": "tr|A0A1D5P5H2-1|A0A1D5P5H2_CHICK Computationally mapped isoform of Mbt domain containing 1 OS=Gallus gallus OX=9031 GN=MBTD1 PE=4 SV=2 CANONICAL=A0A1D5PV94-1" }, "locus": { "chromosome": "18", "start_pos": 5717180, "end_pos": 5695637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070638.1", "url": "https://www.ensembl.org/id/ENSGALT00010070638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043329.1", "url": "https://www.ensembl.org/id/ENSGALP00010043329.1" } ] } }, { "isoform_ac": "A0A1D5PV94-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94/entry", "sequence": { "sequence": "MFDGYDSCSEDTSSSSSSDESEEEVSPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVPVEGFSWGSYINSNSFTAAPVTCFKHAPMGTCWGDISEGVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSNLDFWCNVCGSDIHPVGWCATSGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFRTSMRVEVVDKTHLCRTRVAVVENVIGGRLRLVYEESEDKTDDFWCHMYSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDAPSHLFLKVKEVDTAGEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETDSIAAPVKLFNKEVPNHGFHVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESPDLYPVGWCQLTGYQLQPPAPQSSRDNQSSSSKQKKKSKSQQYKGHKKMTSLQLKEELLDGEEYSFLQGASDQESNGSASYYIKQEP", "length": 628, "header": "tr|A0A1D5PV94-1|A0A1D5PV94_CHICK Isoform 1 of Mbt domain containing 1 OS=Gallus gallus OX=9031 GN=MBTD1 PE=4 SV=1 CANONICAL=A0A1D5PV94-1" }, "locus": { "chromosome": "18", "start_pos": 5714142, "end_pos": 5695637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070637.1", "url": "https://www.ensembl.org/id/ENSGALT00010070637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043328.1", "url": "https://www.ensembl.org/id/ENSGALP00010043328.1" } ] } }, { "isoform_ac": "A0A8V1AIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV3/entry", "sequence": { "sequence": "MFDGYDSCSEDTSSSSSSDESEEEVSPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQVAGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVPVEGFSWGSYINSNSFTAAPVTCFKHAPMGTCWGDISEGVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSNLDFWCNVCGSDIHPVGWCATSGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFRTSMRVEVVDKTHLCRTRVAVVENVIGGRLRLVYEESEDKTDDFWCHMYSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDAPSHLFLKVKEVDTAGEWFKEGMKLEAIDPLNLSAICVATIRKVIQNSHSNGLTTSGKLTQ", "length": 428, "header": "tr|A0A8V1AIV3-1|A0A1D5PV94_CHICK Computationally mapped isoform of Mbt domain containing 1 OS=Gallus gallus OX=9031 GN=MBTD1 PE=4 SV=1 CANONICAL=A0A1D5PV94-1" }, "locus": { "chromosome": "18", "start_pos": 5714142, "end_pos": 5700209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070636.1", "url": "https://www.ensembl.org/id/ENSGALT00010070636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043327.1", "url": "https://www.ensembl.org/id/ENSGALP00010043327.1" } ] } }, { "isoform_ac": "A0A8V1AKY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY8/entry", "sequence": { "sequence": "MDSSEIGCSHLECVHLHIRCVAVINQNIRINDLWRNQEKNTEHLSQTERKRRDSFGMFDGYDSCSEDTSSSSSSDESEEEVSPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQVAGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVPVEGFSWGSYINSNSFTAAPVTCFKHAPMGTCWGDISEGVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSNLDFWCNVCGSDIHPVGWCATSGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFRTSMRVEVVDKTHLCRTRVAVVENVIGGRLRLVYEESEDKTDDFWCHMYSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDAPSHLFLKVKEVDTAGEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETDSIAAPVKLFNKEVPNHGFHVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESPDLYPVGWCQLTGYQLQPPAPQSSRDNQSSSSKQKKKSKSQQYKGHKKMTSLQLKEELLDGEEYSFLQGASDQESNGSASYYIKQEP", "length": 686, "header": "tr|A0A8V1AKY8-1|A0A1D5PV94_CHICK Computationally mapped isoform of Mbt domain containing 1 OS=Gallus gallus OX=9031 GN=MBTD1 PE=4 SV=1 CANONICAL=A0A1D5PV94-1" }, "locus": { "chromosome": "18", "start_pos": 5714566, "end_pos": 5695637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070635.1", "url": "https://www.ensembl.org/id/ENSGALT00010070635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043326.1", "url": "https://www.ensembl.org/id/ENSGALP00010043326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex binding", "id": "GO:0062060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062060", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "histone H4K20me2 reader activity", "id": "GO:0140005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" }, { "name": "histone H4K20me1 reader activity", "id": "GO:0140117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140117", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PV94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PV94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" }, { "id": "PS51024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FCS-type", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 80, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PV94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV94" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 245, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P874-1", "uniprot_ac": "A0A1D5P874", "uniprot_id": "A0A1D5P874_CHICK", "mass": { "chemical_mass": 114467.0, "monoisotopic_mass": 114467.0 }, "refseq": { "ac": "XP_420421", "name": "ubiquitin carboxyl-terminal hydrolase 38 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420421" }, "gene_names": [ { "name": "USP38", "type": "recommended", "evidence": [ { "id": "A0A1D5P874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ] }, { "name": "USP38", "type": "synonym", "evidence": [ { "id": "XP_420421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420421" } ] } ], "protein_names": [ { "name": "Ubiquitin specific peptidase 38", "type": "synonym", "evidence": [ { "id": "A0A1D5P874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 38 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420421" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_420421.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420421" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP38", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874", "locus": { "chromosome": "4", "start_pos": 30017249, "end_pos": 30000604, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007885", "url": "https://www.ensembl.org/id/ENSGALG00010007885" } ] } } ], "crossref": [ { "id": "A0A1D5P874", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P874", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009886", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009886", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02664", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02664", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422455", "url": "https://www.ncbi.nlm.nih.gov/gene/422455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AFVCDSV", "url": "https://omabrowser.org/oma/group/AFVCDSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P874", "url": "https://www.orthodb.org/?gene=A0A1D5P874", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHV2", "url": "https://www.orthodb.org/?gene=F1NHV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P874-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHV2", "url": "https://www.uniprot.org/uniprotkb/F1NHV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHV2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRVIVRRVVELAETPLSQAQCRAMFALGTRLVLQGPDAFQRQVGRQVLEAYGRYHRAEFEAFFNRGLVLGLLQRGYGELSCRDPAILDYIQAGLRLIMSCPSVLELFELLQVEALRLVCERPAPPLCARLCQLLGDFPQCLPRGRKLSLAFCQQLVRSIAHFQSQGSREAELRLYVSQVTQVSGLLRSVWKAEPDTLLPSLQELFAVIAAADTPFEPSVALASLVQHIPLQMITVLIMSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVETWVIALLKGLAAVQKFTILIDVTLMKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLVVPHVVSLVHSFKSDGLPSSTAFLMQLAELIHCMMYHYSGFPELYEPILEVFKDMPKPSEEKMRLILSQSAWTSQSNSLPSCLSRLSGKSETGKTGLINLGNTCYMNSIIQALFMATDFRRHVLSLNLNGCNSLMRKLQHLFAFLAHTQREAYAPRIFLEASRPPWFTPQSQQDCSEYLRFLLNRLHEEERTLKALSSAKAAESRKNEESQAQETVHKAQVFAEALCKGSEERTLIERMFGGKLKTTICCLNCKSTSQKEEAFTDLSLAFCPPTSLESAGVKCLEHSEIKDGSVVQSSISATPAGETPPSSLEINGGCNAITNEGILKDSAEPNSEPKSEFNKDQDSRDVSSALVGKNTPSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIIEEPEYLILTLLRFSYDPKCHIRRKILDSVSLPLLLELPVRRATSPLAVVSGSWSVDVEISDIGENLAKKLKPSGADEVSCPQLVPYVLSSVVVHSGVSSESGHYYSYARNVTGSGSSGQCHQSKAFSLISTQNKLLAEEGPCTVIENELDTEMPKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLIYKKQNSTCGYNTNSANGLWVNGDPPLQKDLMDAITKDNKLYLQEQELSARTQALQAASASCSFRPNGFDDNDPPGSCGPAGGGGGGGFSTVGRLVF", "length": 1035, "header": "tr|A0A1D5P874-1|A0A1D5P874_CHICK Isoform 1 of Ubiquitin specific peptidase 38 OS=Gallus gallus OX=9031 GN=USP38 PE=4 SV=1 CANONICAL=A0A1D5P874-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P874-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874/entry", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRVIVRRVVELAETPLSQAQCRAMFALGTRLVLQGPDAFQRQVGRQVLEAYGRYHRAEFEAFFNRGLVLGLLQRGYGELSCRDPAILDYIQAGLRLIMSCPSVLELFELLQVEALRLVCERPAPPLCARLCQLLGDFPQCLPRGRKLSLAFCQQLVRSIAHFQSQGSREAELRLYVSQVTQVSGLLRSVWKAEPDTLLPSLQELFAVIAAADTPFEPSVALASLVQHIPLQMITVLIMSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVETWVIALLKGLAAVQKFTILIDVTLMKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLVVPHVVSLVHSFKSDGLPSSTAFLMQLAELIHCMMYHYSGFPELYEPILEVFKDMPKPSEEKMRLILSQSAWTSQSNSLPSCLSRLSGKSETGKTGLINLGNTCYMNSIIQALFMATDFRRHVLSLNLNGCNSLMRKLQHLFAFLAHTQREAYAPRIFLEASRPPWFTPQSQQDCSEYLRFLLNRLHEEERTLKALSSAKAAESRKNEESQAQETVHKAQVFAEALCKGSEERTLIERMFGGKLKTTICCLNCKSTSQKEEAFTDLSLAFCPPTSLESAGVKCLEHSEIKDGSVVQSSISATPAGETPPSSLEINGGCNAITNEGILKDSAEPNSEPKSEFNKDQDSRDVSSALVGKNTPSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIIEEPEYLILTLLRFSYDPKCHIRRKILDSVSLPLLLELPVRRATSPLAVVSGSWSVDVEISDIGENLAKKLKPSGADEVSCPQLVPYVLSSVVVHSGVSSESGHYYSYARNVTGSGSSGQCHQSKAFSLISTQNKLLAEEGPCTVIENELDTEMPKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLIYKKQNSTCGYNTNSANGLWVNGDPPLQKDLMDAITKDNKLYLQEQELSARTQALQAASASCSFRPNGFDDNDPPGSCGPAGGGGGGGFSTVGRLVF", "length": 1035, "header": "tr|A0A1D5P874-1|A0A1D5P874_CHICK Isoform 1 of Ubiquitin specific peptidase 38 OS=Gallus gallus OX=9031 GN=USP38 PE=4 SV=1 CANONICAL=A0A1D5P874-1" }, "locus": { "chromosome": "4", "start_pos": 30017086, "end_pos": 30000803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018761.1", "url": "https://www.ensembl.org/id/ENSGALT00010018761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010311.1", "url": "https://www.ensembl.org/id/ENSGALP00010010311.1" } ] } }, { "isoform_ac": "F1NHV2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHV2/entry", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRVIVRRVVELAETPLSQAQCRAMFALGTRLVLQGPDAFQRQVGRQVLEAYGRYHRAEFEAFFNRGLVLGLLQRGYGELSCRDPAILDYIQAGLRLIMSCPSVLELFELLQVEALRLVCERPAPPLCARLCQLLGDFPQCLPRGRKLSLAFCQQLVRSIAHFQSQGSREAELRLYVSQVTQVSGLLRSVWKAEPDTLLPSLQELFAVIAAADTPFEPSVALASLVQHIPLQMITVLIMSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVETWVIALLKGLAAVQKFTILIDVTLMKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLVVPHVVSLVHSFKSDGLPSSTAFLMQLAELIHCMMYHYSGFPELYEPILEVFKDMPKPSEEKMRLILSQSAWTSQSNSLPSCLSRLSGKSETGKTGLINLGNTCYMNSIIQALFMATDFRRHVLSLNLNGCNSLMRKLQHLFAFLAHTQREAYAPRIFLEASRPPWFTPQSQQDCSEYLRFLLNRLHEEERTLKALSSAKAAESRKNEESQAQETVHKAQVFAEALCKGSEERTLIERMFGGKLKTTICCLNCKSTSQKEEAFTDLSLAFCPPTSLESAGVKCLEHSEIKDGSVVQSSISATPAGETPPSSLEINGGCNAITNEGILKDSAEPNSEPKSEFNKDQDSRDVSSALVGKNTPSVTDLLNYFLAPEILSGDNKYYCEKCASLQNAEKTMQIIEEPEYLILTLLRFSYDPKCHIRRKILDSVSLPLLLELPVRRATSPLAVVSGSWSVDVEISDIGENLAKKLKPSGADEVSCPQLVPYVLSSVVVHSGVSSESGHYYSYARNVTGSGSSGQCHQSKAFSLISTQNKLLAEEGPCTVIENELDTEMPKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLIYKKQNSTCGYNTNSANGLWVNGDPPLQKDLMDAITKDNKLYLQFSRTLPLSCLA", "length": 993, "header": "tr|F1NHV2-1|A0A1D5P874_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 38 OS=Gallus gallus OX=9031 GN=USP38 PE=4 SV=3 CANONICAL=A0A1D5P874-1" }, "locus": { "chromosome": "4", "start_pos": 30016394, "end_pos": 30000803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018759.1", "url": "https://www.ensembl.org/id/ENSGALT00010018759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010309.1", "url": "https://www.ensembl.org/id/ENSGALP00010010309.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 653, "start_aa": "Thr", "end_pos": 653, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr653", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3Z8K5-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRMIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPLLCARLSDLLTDFVQCVPKGKLSITFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSNLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTRALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPTEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRIQSSHKPSEGLGCTETCLQEVTNKVAVPSESPSTGGSEKTLIEKMFGGKLRTHICCLNCRSTSHKVEAFTDLSLAFCPSPSVEDSSFQDPASLPSAQDDGLMQTSVTDAEEEPVVCNPAAAAFVCDSVVNERRLGSPPVEFPCAKNSSVPGESAKILVSKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTSLSSLSEGWSADADFTDVNENLAKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMRPQSESLSLTPSQSSLLGGESPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLFYKKQSRTNGVRSDNPASGVWVNGEPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNAVGRLVF", "length": 1041 }, "evidence": [ { "id": "A0A1D5P874", "url": "https://omabrowser.org/oma/group/A0A1D5P874/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L5H8-1", "protein_name": "Ubiquitin specific peptidase 38", "gene_name": "USP38", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRVIVRKVVESAENWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVHRMVCERPEPHLCARLSDLLSDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSNLLQNIWKGEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFRSDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRVSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQPSHKPSESPGCSETSLQEVANKAAGLTETSCTSDGEKTLIEKMFGGKLQTHICCLNCRSTSQKVEAFTDLSLAFCPSSSMENLSFQDPASSGSSHDGGLMQGRVPGPSKEPGVYNPATAAFACDSAVSEGMVGSPDEFRCAEDISVPNDSRKMLVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTTSFSSLSESWSLDVDFTDISENLAKKLKPSGTEEACCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTECSYQLCHQPETLALASSQGHLPGRDSPSAVIEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQNSTNSLGGSNSTTGLWVNGDPPLQKELMEAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF", "length": 1041 }, "evidence": [ { "id": "A0A1D5P874", "url": "https://omabrowser.org/oma/group/A0A1D5P874/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55BI4-1", "protein_name": "Peptidase C19 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNYPHNTDNNDIILLLIDCISYKDISRQSIDRIKQFVENENDFKKLVNNLNIGLDYISQQQQPTATTIITNNGDFKSQLYSIMSDIFQTVYIKNKDIIEFNNFISICFTPSLLTSLLTPIISHNITSFLQIFKIILNCKIKHLNVFTVENINDIQYFYRSLKNIATRYPKIINRNSNILNEELLTKPISMLLVKIIIDDLSTLPITMEPKQYDEIVYQYTKTIQLFWNSNQLSSIQVSMEHMFKKLMMSSSSSSSSSSNSSSSSSNNEIITPSISNVLNQSPIELIPLFINIIDNGSVSDIDLLETITKLTQWPLTPTNSKWILETFNSLIRSKKTTLLASIVVESALSVIKQMFVLPLLSSSFEILQKMLLGYQHSPDTFHSIIDLFPIVIELLLMFHNKINAIQHQPNGVDDGDGDDAIKRIEFINQNTQQTVYKLINECNKNRKELLLISIKNTSQPSKYRNTILITLIKFCQLSYTLMFHHTGYPELYAPLLESLNKCNHLLPSIPSEFQMKRLLQDNEWQSLDSMVFENIKLNRVLTDRSGLINLGNTCYMNSFLQSLYMTIPFRNYLLFKIDQNLIKFINNNNNNNNNNTNNNDNNNDEEIFKIYSKEILKRPQLLKQIQLLFGNLRLSIKESISPNLFLQSLPIEFQTGQQHDSFEFGKSLLDHLDLIFKQQIKNEQQQQQQQQQQQQLNLKNSNNASNSTNIVTEISNQFGGKLSQITTCRKCSSESIKVEEFLELSLPFHDHRKQQYQLEEMINGYLSNEELIGDNRYHCSKCNSLQDADKIIEINETPNHLIIGLNRFHFSRETKSIEKLLNHVDYPLNLNLPFIQNHQKDRNNDEIKNENENEIKNENENENEKEDFKKIKINENDDDDDDDDGDENSKEKKKKSIIKLSNYSLYSVIIHSGRSPTHGHYYNYSCTSSNNSNGKPVDWCLFNDSMVKITDVQTFKNINKQFYTDVPYILFYVKNPSLPSSPIDNTIDTTNNDDVSPWIKQSIIKENQNLLSKFNNTKNKNSNILEQFHTSGYFKKK", "length": 1037 }, "evidence": [ { "id": "A0A1D5P874", "url": "https://omabrowser.org/oma/group/A0A1D5P874/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BW70-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 38", "gene_name": "Usp38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRMIVRKVVEFAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSVDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPVLCARLSDLLTDFVQCVPKGKLSVTFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSTLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPSEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRVQSSHKPSEGLDCAETCLQEVTSKVAVPTESPGTGDSEKTLIEKMFGGKLRTHICCLNCGSTSHKVEAFTDLSLAFCPSPSVEDLSFQDTASLPSAQDDGLMQTSVADPEEEPVVYNPATAAFVCDSVVNQRVLGSPPVEFHCAESSSVPEESAKILISKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDINENLPKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMCPQSESLALAPSQSCLLGVESPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQSRANGIDSDNPASGVWANGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF", "length": 1042 }, "evidence": [ { "id": "A0A1D5P874", "url": "https://omabrowser.org/oma/group/A0A1D5P874/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NB14-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 38", "gene_name": "USP38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLSLAFCPSSSLENMSVQDPASSPSIQDGGLMQASVPGPSEEPVVYNPTTAAFICDSLVNEKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF", "length": 1042 }, "evidence": [ { "id": "A0A1D5P874", "url": "https://omabrowser.org/oma/group/A0A1D5P874/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "protein K33-linked deubiquitination", "id": "GO:1990168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990168", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P874", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P874" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" }, { "start_pos": 911, "end_pos": 913, "annotation": "n_glycosylation_sequon" }, { "start_pos": 944, "end_pos": 946, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P874-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1035, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P874-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P874" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 653 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 860, "end_pos": 862 }, { "start_pos": 911, "end_pos": 913 }, { "start_pos": 944, "end_pos": 946 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PTS3-1", "uniprot_ac": "A0A1D5PTS3", "uniprot_id": "A0A1D5PTS3_CHICK", "mass": { "chemical_mass": 8900.0, "monoisotopic_mass": 8900.0 }, "refseq": { "ac": "NP_001289095", "name": "immediate early response 3-interacting protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289095" }, "gene_names": [ { "name": "IER3IP1", "type": "recommended", "evidence": [ { "id": "A0A1D5PTS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ] }, { "name": "IER3IP1", "type": "synonym", "evidence": [ { "id": "NP_001289095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289095" } ] } ], "protein_names": [ { "name": "Immediate early response 3-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PTS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3/entry#names_and_taxonomy" } ] }, { "name": "immediate early response 3-interacting protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001289095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289095" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU300606.1, BU126921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU300606.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289095" } ] }, { "annotation": "Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size. Required for secretion of extracellular matrix proteins. Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors. Acts as a regulator of the unfolded protein response (UPR).", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3#function" }, { "database": "UniProtKB", "id": "ARBA00045999", "url": "https://www.uniprot.org/uniprotkb/ARBA00045999#function" }, { "database": "UniProtKB", "id": "A0A8V0YCU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU4#function" }, { "database": "UniProtKB", "id": "A0A8V0YHI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IER3IP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3", "locus": { "chromosome": "Z", "start_pos": 2089140, "end_pos": 2086059, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011367", "url": "https://www.ensembl.org/id/ENSGALG00010011367" } ] } } ], "crossref": [ { "id": "A0A1D5PTS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PTS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032061", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101749130", "url": "https://www.ncbi.nlm.nih.gov/gene/101749130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749130", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQTVMRM", "url": "https://omabrowser.org/oma/group/VQTVMRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PTS3", "url": "https://www.orthodb.org/?gene=A0A1D5PTS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCU4", "url": "https://www.orthodb.org/?gene=A0A8V0YCU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHI2", "url": "https://www.orthodb.org/?gene=A0A8V0YHI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15858:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15858:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTLYALLQAGLLVVNAIAVLHEERFLRHVGWGSDQGIGGFGEEPGIKAQLTNLIRSIRTVMRVPLIAVNSVTIVLLLLFG", "length": 82, "header": "tr|A0A1D5PTS3-1|A0A1D5PTS3_CHICK Isoform 1 of Immediate early response 3-interacting protein 1 OS=Gallus gallus OX=9031 GN=IER3IP1 PE=3 SV=1 CANONICAL=A0A1D5PTS3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PTS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3/entry", "sequence": { "sequence": "MAFTLYALLQAGLLVVNAIAVLHEERFLRHVGWGSDQGIGGFGEEPGIKAQLTNLIRSIRTVMRVPLIAVNSVTIVLLLLFG", "length": 82, "header": "tr|A0A1D5PTS3-1|A0A1D5PTS3_CHICK Isoform 1 of Immediate early response 3-interacting protein 1 OS=Gallus gallus OX=9031 GN=IER3IP1 PE=3 SV=1 CANONICAL=A0A1D5PTS3-1" }, "locus": { "chromosome": "Z", "start_pos": 2087547, "end_pos": 2086108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027185.1", "url": "https://www.ensembl.org/id/ENSGALT00010027185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015479.1", "url": "https://www.ensembl.org/id/ENSGALP00010015479.1" } ] } }, { "isoform_ac": "A0A8V0YCU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU4/entry", "sequence": { "sequence": "MAFTLYALLQAGLLVVNAIAVLHEERFLRHVGWGSDQGIGGFGEEPGIKAQLTNLIRSIRTVMRVGASQSSASSSSWNQSCCSQHTWLFSYPQHVLRAQSCCEVLSRWLLPLVCSAAALEMR", "length": 122, "header": "tr|A0A8V0YCU4-1|A0A1D5PTS3_CHICK Computationally mapped isoform of Immediate early response 3-interacting protein 1 OS=Gallus gallus OX=9031 GN=IER3IP1 PE=3 SV=1 CANONICAL=A0A1D5PTS3-1" }, "locus": { "chromosome": "Z", "start_pos": 2089121, "end_pos": 2086108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027186.1", "url": "https://www.ensembl.org/id/ENSGALT00010027186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015480.1", "url": "https://www.ensembl.org/id/ENSGALP00010015480.1" } ] } }, { "isoform_ac": "A0A8V0YHI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI2/entry", "sequence": { "sequence": "MAFTLYALLQAGLLVVNAIAVLHEERFLRHVGWGSDQGIGGFGEEPGIKAQLTNLIRSIRTVMRAAVSVCHPVANITLLTTKYVSSKPC", "length": 89, "header": "tr|A0A8V0YHI2-1|A0A1D5PTS3_CHICK Computationally mapped isoform of Immediate early response 3-interacting protein 1 OS=Gallus gallus OX=9031 GN=IER3IP1 PE=3 SV=1 CANONICAL=A0A1D5PTS3-1" }, "locus": { "chromosome": "Z", "start_pos": 2087285, "end_pos": 2086108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027184.1", "url": "https://www.ensembl.org/id/ENSGALT00010027184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015478.1", "url": "https://www.ensembl.org/id/ENSGALP00010015478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749130", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZY2-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1JQC2-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3E834-1", "protein_name": "Protein transport protein YOS1", "gene_name": "YOS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLFGLGRLFYVILLLINAVAVLSEERFLRRIGLGRSNDETPVFGQDQNTTKSKVVQLIGAVQTLLRIPLIGINILVIVYELLLG", "length": 85 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q4VBI2-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "ier3ip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFTLYALIQTAILFTNAIAVLHEERFLSKIGWGAEQGVGGFGDDPGIKAQLLNLIRSVRTVMRVPLIAVNSVCIVLLLLFG", "length": 82 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CR20-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "Ier3ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFTLYSLMQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSITIVLLLLFG", "length": 82 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTE1-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "Dmel\\CG32069", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFTLWTLIESSLLCLNAVCILHEERFLAKFGWGRQAGQQDFGAPTAKDQVLNLIRSIRTVAKIPLIFLNIIAIIFKLLLG", "length": 80 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5U9-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82 }, "evidence": [ { "id": "A0A1D5PTS3", "url": "https://omabrowser.org/oma/group/A0A1D5PTS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "regulation of fibroblast apoptotic process", "id": "GO:2000269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000269", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "positive regulation of protein secretion", "id": "GO:0050714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "organ growth", "id": "GO:0035265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035265", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "positive regulation of extracellular matrix constituent secretion", "id": "GO:0003331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PGS5-1", "uniprot_ac": "A0A1D5PGS5", "uniprot_id": "A0A1D5PGS5_CHICK", "mass": { "chemical_mass": 60194.0, "monoisotopic_mass": 60194.0 }, "refseq": { "ac": "XP_015141197", "name": "TBC1 domain family member 19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141197" }, "gene_names": [ { "name": "TBC1D19", "type": "recommended", "evidence": [ { "id": "A0A1D5PGS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5" } ] }, { "name": "TBC1D19", "type": "synonym", "evidence": [ { "id": "XP_015141197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141197" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 19 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141197" } ] }, { "name": "TBC1 domain family member 19", "type": "synonym", "evidence": [ { "id": "A0A1D5PGS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D19", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5", "locus": { "chromosome": "4", "start_pos": 72667408, "end_pos": 72712760, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010722", "url": "https://www.ensembl.org/id/ENSGALG00010010722" } ] } } ], "crossref": [ { "id": "A0A1D5PGS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PGS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029673", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422800", "url": "https://www.ncbi.nlm.nih.gov/gene/422800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422800", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422800", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFKWIMR", "url": "https://omabrowser.org/oma/group/VFKWIMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGS5", "url": "https://www.orthodb.org/?gene=A0A1D5PGS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y650", "url": "https://www.orthodb.org/?gene=A0A8V0Y650", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9Z6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEM4", "url": "https://www.orthodb.org/?gene=A0A8V0YEM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16110:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16110:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PGS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y650", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y650", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y650-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEQDSGLSLTIARIVQRLKGSSLHSQLERQARISLHNPEIKLESLKEDIKDFLKTSGWEKKLQNAVYSELNVFPSPCHPAAPPEHMKEPLAYMRKAQGSWEKRILKSLNSMCTELSIPLAQKRPASEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLMNLRNPNYENGEQLSFRNHLGLIQVPLKVKDIPELKEDFSELDLNVGQLGIDDSAQVPPEFFENEHVRIGQKVLAEQDSAAAQQYVRQGCPTALRADLWALILNISNQPEDILYYEQLKSNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLEHFAYSSATPPKSYIRGKLGIEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 526, "header": "tr|A0A1D5PGS5-1|A0A1D5PGS5_CHICK Isoform 1 of TBC1 domain family member 19 OS=Gallus gallus OX=9031 GN=TBC1D19 PE=4 SV=1 CANONICAL=A0A1D5PGS5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGS5/entry", "sequence": { "sequence": "MLEQDSGLSLTIARIVQRLKGSSLHSQLERQARISLHNPEIKLESLKEDIKDFLKTSGWEKKLQNAVYSELNVFPSPCHPAAPPEHMKEPLAYMRKAQGSWEKRILKSLNSMCTELSIPLAQKRPASEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLMNLRNPNYENGEQLSFRNHLGLIQVPLKVKDIPELKEDFSELDLNVGQLGIDDSAQVPPEFFENEHVRIGQKVLAEQDSAAAQQYVRQGCPTALRADLWALILNISNQPEDILYYEQLKSNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLEHFAYSSATPPKSYIRGKLGIEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 526, "header": "tr|A0A1D5PGS5-1|A0A1D5PGS5_CHICK Isoform 1 of TBC1 domain family member 19 OS=Gallus gallus OX=9031 GN=TBC1D19 PE=4 SV=1 CANONICAL=A0A1D5PGS5-1" }, "locus": { "chromosome": "4", "start_pos": 72712488, "end_pos": 72667710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025592.1", "url": "https://www.ensembl.org/id/ENSGALT00010025592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014434.1", "url": "https://www.ensembl.org/id/ENSGALP00010014434.1" } ] } }, { "isoform_ac": "A0A8V0Y650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y650/entry", "sequence": { "sequence": "MLEQDSGLSLTIARIVQRLKGSSLHSQLERQARISLHNPEIKLESLKEDIKDFLKTSGWEKKLQNAVYSELNVFPSPCHPAAPPEHMKEPLAYMRKAQGSWEKRILKSLNSMCTELSIPLAQKRPASEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEKEDFSELDLNVGQLGIDDSAQVPPEFFENEHVRIGQKVLAEQDSAAAQQYVRQGCPTALRADLWALILNISNQPEDILYYEQLKSNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLEHFAYSSATPPKSYIRGKLGIEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 489, "header": "tr|A0A8V0Y650-1|A0A1D5PGS5_CHICK Computationally mapped isoform of TBC1 domain family member 19 OS=Gallus gallus OX=9031 GN=TBC1D19 PE=4 SV=1 CANONICAL=A0A1D5PGS5-1" }, "locus": { "chromosome": "4", "start_pos": 72712488, "end_pos": 72667710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025585.1", "url": "https://www.ensembl.org/id/ENSGALT00010025585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014431.1", "url": "https://www.ensembl.org/id/ENSGALP00010014431.1" } ] } }, { "isoform_ac": "A0A8V0Y9Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z6/entry", "sequence": { "sequence": "MKLECKSQPRHPHPSLITQISLHNPEIKLESLKEDIKDFLKTSGWEKKLQNAVYSELNVFPSPCHPAAPPEHMKEPLAYMRKAQGSWEKRILKSLNSMCTELSIPLAQKRPASEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLMNLRNPNYENGEQLSFRNHLGLIQVPLKVKDIPELKEDFSELDLNVGQLGIDDSAQVPPEFFENEHVRIGQKVLAEQDSAAAQQYVRQGCPTALRADLWALILNISNQPEDILYYEQLKSNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLEHFAYSSATPPKSYIRGKLGIEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 512, "header": "tr|A0A8V0Y9Z6-1|A0A1D5PGS5_CHICK Computationally mapped isoform of TBC1 domain family member 19 OS=Gallus gallus OX=9031 GN=TBC1D19 PE=4 SV=1 CANONICAL=A0A1D5PGS5-1" }, "locus": { "chromosome": "4", "start_pos": 72709742, "end_pos": 72667710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025580.1", "url": "https://www.ensembl.org/id/ENSGALT00010025580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014430.1", "url": "https://www.ensembl.org/id/ENSGALP00010014430.1" } ] } }, { "isoform_ac": "A0A8V0YEM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM4/entry", "sequence": { "sequence": "MLEQDSGLSLTIARIVQRLKGSSLHSQLERQARISLHNPEIKLESLKEDIKDFLKTSGWEKKLQNAVYSELNVFPSPCHPAAPPEHMKEPLAYMRKAQGSWEKRILKSLNSMCTELSIPLAQKRPASEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLMNLRNPNYENGEQLSFRNHLGLIQVPLKVKDIPELKEDFSELDLNVGQLGIDDSAQVPPEFFENEHVRIGQKVLAEQDSAAAQQYVRQGCPTALRADLWALILNISNQPEDILYYEQLKSNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLEHFAYSSATPPKSYIRDLPSSLPFSSLVPSSGKLGIEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTHLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 541, "header": "tr|A0A8V0YEM4-1|A0A1D5PGS5_CHICK Computationally mapped isoform of TBC1 domain family member 19 OS=Gallus gallus OX=9031 GN=TBC1D19 PE=4 SV=1 CANONICAL=A0A1D5PGS5-1" }, "locus": { "chromosome": "4", "start_pos": 72712488, "end_pos": 72667710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025589.1", "url": "https://www.ensembl.org/id/ENSGALT00010025589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014433.1", "url": "https://www.ensembl.org/id/ENSGALP00010014433.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422800", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8N5T2-1", "protein_name": "TBC1 domain family member 19", "gene_name": "TBC1D19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYENGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT", "length": 526 }, "evidence": [ { "id": "A0A1D5PGS5", "url": "https://omabrowser.org/oma/group/A0A1D5PGS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VMT4-1", "protein_name": "Rab-GAP TBC domain-containing protein", "gene_name": "Dmel\\CG7742", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEELQDASIHHMTAKVIAAIKNTKSYEPIYKELQKLVCNPSVDTHDMRNTLEDAIKSAGLETEIRNIVYNLVRTRLSKTDDKNLANKQGAKPTVSDPLGYLKRAGVLWDRRVRKSLNAMCTELKVPLHGQPRISADREDFMAKWNELSNYNMDLANYRPVYAPKDLLEVLLSLKGPAKTTENTDQIPQWEFSHIALPVKNLFELRAHYADLLRSDSYLGVPDLTVQCQRILEARHAPMCQQFLKKGCTPAPYRGALWASVLDSKLHDYDIEYWQKLRNAVWTTDHIVDKLVFKDIQLTASNDDQYFVFEDVLYQVLLCFSRDTDIGGCVEYETFPVKGKTYEGPPSGVVPFHGICMFAAPFCYLYDSPVSLYYTFRAFYIRYCHRLTTINTHPQGIVSLCLLFEKLLQTYEPQLWSHFRELQIQPLRVVFKWLMRAFSGHLPPDQLLVLWDLILGFDSLEILPLFAIIILSFRKESIMQVASLDSIEAILADLSSIKVLPLVQLALSRD", "length": 509 }, "evidence": [ { "id": "A0A1D5PGS5", "url": "https://omabrowser.org/oma/group/A0A1D5PGS5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 339 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P545-1", "uniprot_ac": "A0A1D5P545", "uniprot_id": "A0A1D5P545_CHICK", "mass": { "chemical_mass": 16845.0, "monoisotopic_mass": 16845.0 }, "refseq": { "ac": "XP_046763575", "name": "cold shock domain-containing protein C2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046763575" }, "gene_names": [ { "name": "CSDC2", "type": "recommended", "evidence": [ { "id": "A0A1D5P545", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P545" } ] }, { "name": "CSDC2", "type": "synonym", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5", "locus": { "chromosome": "4", "start_pos": 69050711, "end_pos": 69075232, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015165", "url": "https://www.ensembl.org/id/ENSGALG00010015165" } ] } } ], "crossref": [ { "id": "A0A1D5PKX5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PKX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041717", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041717", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429811", "url": "https://www.ncbi.nlm.nih.gov/gene/429811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429811", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMYASHL", "url": "https://omabrowser.org/oma/group/FMYASHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKX5", "url": "https://www.orthodb.org/?gene=A0A1D5PKX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK34", "url": "https://www.orthodb.org/?gene=A0A8V0YK34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT66", "url": "https://www.orthodb.org/?gene=A0A8V0YT66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMFDPVPIKQEAMDPVSVSYPSNYMDQMKPNKYSVIYSAPSMLHNKFYSNPDGLSNGIQMEPVDLTVNKRNSPPSAGSSPSPLKFQTVHRRTSPGLTLSSPSSPISKFTPSPPGVQPLSMPITIPPVMAAALSRHGLRSPGILPVIQPVVVQPVPFMYAPHLQQPIMVSTVLTDEMDSPSSMQVPVIESFEKPALKKTIKVEPGSEPAKTDFYPERMSPPMTSLSPQEVMLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLTLHRKRHMLV", "length": 347, "header": "tr|A0A1D5PKX5-1|A0A1D5PKX5_CHICK Isoform 1 of KLF transcription factor 3 OS=Gallus gallus OX=9031 GN=KLF3 PE=4 SV=1 CANONICAL=A0A1D5PKX5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5/entry", "sequence": { "sequence": "MLMFDPVPIKQEAMDPVSVSYPSNYMDQMKPNKYSVIYSAPSMLHNKFYSNPDGLSNGIQMEPVDLTVNKRNSPPSAGSSPSPLKFQTVHRRTSPGLTLSSPSSPISKFTPSPPGVQPLSMPITIPPVMAAALSRHGLRSPGILPVIQPVVVQPVPFMYAPHLQQPIMVSTVLTDEMDSPSSMQVPVIESFEKPALKKTIKVEPGSEPAKTDFYPERMSPPMTSLSPQEVMLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLTLHRKRHMLV", "length": 347, "header": "tr|A0A1D5PKX5-1|A0A1D5PKX5_CHICK Isoform 1 of KLF transcription factor 3 OS=Gallus gallus OX=9031 GN=KLF3 PE=4 SV=1 CANONICAL=A0A1D5PKX5-1" }, "locus": { "chromosome": "4", "start_pos": 69064876, "end_pos": 69051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036543.1", "url": "https://www.ensembl.org/id/ENSGALT00010036543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021292.1", "url": "https://www.ensembl.org/id/ENSGALP00010021292.1" } ] } }, { "isoform_ac": "A0A8V0YK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK34/entry", "sequence": { "sequence": "MKPHLRKSYPSNYMDQMKPNKYSVIYSAPSMLHNKFYSNPDGLSNGIQMEPVDLTVNKRNSPPSAGSSPSPLKFQTVHRRTSPGLTLSSPSSPISKFTPSPPGVQPLSMPITIPPVMAAALSRHGLRSPGILPVIQPVVVQPVPFMYAPHLQQPIMVSTVLTDEMDSPSSMQVPVIESFEKPALKKTIKVEPGSEPAKTDFYPERMSPPMTSLSPQEVMLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLTLHRKRHMLV", "length": 335, "header": "tr|A0A8V0YK34-1|A0A1D5PKX5_CHICK Computationally mapped isoform of KLF transcription factor 3 OS=Gallus gallus OX=9031 GN=KLF3 PE=4 SV=1 CANONICAL=A0A1D5PKX5-1" }, "locus": { "chromosome": "4", "start_pos": 69063786, "end_pos": 69051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036544.1", "url": "https://www.ensembl.org/id/ENSGALT00010036544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021293.1", "url": "https://www.ensembl.org/id/ENSGALP00010021293.1" } ] } }, { "isoform_ac": "A0A8V0YT66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT66/entry", "sequence": { "sequence": "MLMFDPVPIKQEAMDPVSVGNRGTPRGTAGCVLSKKKHVEKSYPSNYMDQMKPNKYSVIYSAPSMLHNKFYSNPDGLSNGIQMEPVDLTVNKRNSPPSAGSSPSPLKFQTVHRRTSPGLTLSSPSSPISKFTPSPPGVQPLSMPITIPPVMAAALSRHGLRSPGILPVIQPVVVQPVPFMYAPHLQQPIMVSTVLTDEMDSPSSMQVPVIESFEKPALKKTIKVEPGSEPAKTDFYPERMSPPMTSLSPQEVMLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLTLHRKRHMLV", "length": 369, "header": "tr|A0A8V0YT66-1|A0A1D5PKX5_CHICK Computationally mapped isoform of KLF transcription factor 3 OS=Gallus gallus OX=9031 GN=KLF3 PE=4 SV=1 CANONICAL=A0A1D5PKX5-1" }, "locus": { "chromosome": "4", "start_pos": 69064876, "end_pos": 69051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036542.1", "url": "https://www.ensembl.org/id/ENSGALT00010036542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021291.1", "url": "https://www.ensembl.org/id/ENSGALP00010021291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429811", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LQM3-1", "protein_name": "KLF transcription factor 3", "gene_name": "KLF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLSDKFFQTPEGLSHGMQMEPVDLTVNKRSSPPSAGNSPSSLKFQSSHRRASPGLSLPSSSPPGKKYSPPPPPGVQPFSVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPILQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "length": 346 }, "evidence": [ { "id": "A0A1D5PKX5", "url": "https://omabrowser.org/oma/group/A0A1D5PKX5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A4V3-1", "protein_name": "KLF transcription factor 3", "gene_name": "Klf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLMFDPVPVKQEAMDPVTVSYPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLAHGIQMEPVDLTVNKRGSPPSAAGSPSSLKFPSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVPLSMPPVMAAALTRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPILQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "length": 344 }, "evidence": [ { "id": "A0A1D5PKX5", "url": "https://omabrowser.org/oma/group/A0A1D5PKX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57682-1", "protein_name": "Krueppel-like factor 3", "gene_name": "KLF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLMFDPVPVKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "length": 345 }, "evidence": [ { "id": "A0A1D5PKX5", "url": "https://omabrowser.org/oma/group/A0A1D5PKX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60980-1", "protein_name": "Krueppel-like factor 3", "gene_name": "Klf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLMFDPVPVKQEAMDPVSVSFPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLTHGIQVEPVDLTVNKRGSPPAAGGSPSSLKFPSHRRASPGLSMPSSSPPIKKYSPPSPGVQPFGVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPLLQKKIKIEPGIEPQRTDYYPEEMSPPLMNPVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "length": 344 }, "evidence": [ { "id": "A0A1D5PKX5", "url": "https://omabrowser.org/oma/group/A0A1D5PKX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PKX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKX5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 262, "end_pos": 291, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PMP8-1", "uniprot_ac": "A0A1D5PMP8", "uniprot_id": "A0A1D5PMP8_CHICK", "mass": { "chemical_mass": 63989.0, "monoisotopic_mass": 63989.0 }, "refseq": { "ac": "XP_003640437", "name": "synapsin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640437" }, "gene_names": [ { "name": "SYN3", "type": "recommended", "evidence": [ { "id": "A0A1D5PMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ] }, { "name": "SYN3", "type": "synonym", "evidence": [ { "id": "XP_003640437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640437" } ] } ], "protein_names": [ { "name": "Synapsin III", "type": "synonym", "evidence": [ { "id": "A0A1D5PMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8/entry#names_and_taxonomy" } ] }, { "name": "synapsin-3", "type": "synonym", "evidence": [ { "id": "XP_003640437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640437" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640437" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8", "locus": { "chromosome": "1", "start_pos": 53271890, "end_pos": 53068097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015391", "url": "https://www.ensembl.org/id/ENSGALG00010015391" } ] } } ], "crossref": [ { "id": "A0A1D5PMP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PMP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033589", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033589", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857420", "url": "https://www.ncbi.nlm.nih.gov/gene/100857420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857420", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857420", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IGSAYKC", "url": "https://omabrowser.org/oma/group/IGSAYKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMP8", "url": "https://www.orthodb.org/?gene=A0A1D5PMP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP4", "url": "https://www.orthodb.org/?gene=A0A8V0YKP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYT6", "url": "https://www.orthodb.org/?gene=A0A8V0YYT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10841:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10841:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003640437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFLRRRLSDSSFVANLPNGYMMDLQRPDNSTSSPVSPAMERKHPQPPQPSQSSSTGTSIFSSISSAMKQTTQAAAGLIDHSTSSTPPVAQKPKILLVIDDAHTEWAKYFQGKKVNGEFDIRVEQAEFSELNLAAYVTGGCMVDMQVMRNGTKVVRSFKPDFVLIRQHAYSMALGEDFRSLIIGLQYGGIHAVNSLYSIYNFCSKPWVFSQLIKIFNSLGPEKFPLVEQTFFPSHKQMLTTPNFPVVVKLGHAHAGMGKVKVENQYDFRDIASIIAMAKTYATSEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTERYRLWVDACAEMFGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRQLIADLVVSKMTQLVSTAGSTPSPLRPWPPQVQPQTVKTQPGPQLAQLSQPRPPPQGGPRQPQASQPPRTNAPPQQRLSPQGQQPQSPLSTSPQQQRSPGSPQQVRSATGSSPVQASKAGVFPPQQPRPPAQGRAPSQPSPTETSKQQATPQPHLNKSQSLTNTFSISESSQRGNASEDEAKAETIRNLRKSFASLFSD", "length": 582, "header": "tr|A0A1D5PMP8-1|A0A1D5PMP8_CHICK Isoform 1 of Synapsin III OS=Gallus gallus OX=9031 GN=SYN3 PE=3 SV=2 CANONICAL=A0A1D5PMP8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8/entry", "sequence": { "sequence": "MNFLRRRLSDSSFVANLPNGYMMDLQRPDNSTSSPVSPAMERKHPQPPQPSQSSSTGTSIFSSISSAMKQTTQAAAGLIDHSTSSTPPVAQKPKILLVIDDAHTEWAKYFQGKKVNGEFDIRVEQAEFSELNLAAYVTGGCMVDMQVMRNGTKVVRSFKPDFVLIRQHAYSMALGEDFRSLIIGLQYGGIHAVNSLYSIYNFCSKPWVFSQLIKIFNSLGPEKFPLVEQTFFPSHKQMLTTPNFPVVVKLGHAHAGMGKVKVENQYDFRDIASIIAMAKTYATSEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTERYRLWVDACAEMFGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRQLIADLVVSKMTQLVSTAGSTPSPLRPWPPQVQPQTVKTQPGPQLAQLSQPRPPPQGGPRQPQASQPPRTNAPPQQRLSPQGQQPQSPLSTSPQQQRSPGSPQQVRSATGSSPVQASKAGVFPPQQPRPPAQGRAPSQPSPTETSKQQATPQPHLNKSQSLTNTFSISESSQRGNASEDEAKAETIRNLRKSFASLFSD", "length": 582, "header": "tr|A0A1D5PMP8-1|A0A1D5PMP8_CHICK Isoform 1 of Synapsin III OS=Gallus gallus OX=9031 GN=SYN3 PE=3 SV=2 CANONICAL=A0A1D5PMP8-1" }, "locus": { "chromosome": "1", "start_pos": 53269516, "end_pos": 53088407, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036957.1", "url": "https://www.ensembl.org/id/ENSGALT00010036957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021511.1", "url": "https://www.ensembl.org/id/ENSGALP00010021511.1" } ] } }, { "isoform_ac": "A0A8V0YKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP4/entry", "sequence": { "sequence": "MNFLRRRLSDSSFVANLPNGYMMDLQRPDNSTSSPVSPAMERKHPQPPQPSQSSSTGTSIFSSISSAMKQTTQAAAGLIDHSTSSTPPVAQKPKILLVIDDAHTEWAKYFQGKKVNGEFDIRVEQAEFSELNLAAYVTGGCMVDMQVMRNGTKVVRSFKPDFVLIRQHAYSMALGEDFRSLIIGLQYGGIHAVNSLYSIYNFCSKPWVFSQLIKIFNSLGPEKFPLVEQTFFPSHKQMDHQFAMVIFLSEDKTKHKEHHLSPCFLTRTLEFHLTTPNFPVVVKLGHAHAGMGKVKVENQYDFRDIASIIAMAKTYATSEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTERYRLWVDACAEMFGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRQLIADLVVSKMTQLVSTAGSTPSPLRPWPPQVQPQTVKTQPGPQLAQLSQPRPPPQGGPRQPQASQPPRTNAPPQQRLSPQGQQPQSPLSTSPQQQRSPGSPQQVRSATGSSPVQASKAGVFPPQQPRPPAQGRAPSQPSPTETSKQQATPQPHLNKSQSLTNTFSISESSQRGNASEDEAKAETIRNLRKSFASLFSD", "length": 616, "header": "tr|A0A8V0YKP4-1|A0A1D5PMP8_CHICK Computationally mapped isoform of Synapsin III OS=Gallus gallus OX=9031 GN=SYN3 PE=3 SV=1 CANONICAL=A0A1D5PMP8-1" }, "locus": { "chromosome": "1", "start_pos": 53269516, "end_pos": 53088407, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036959.1", "url": "https://www.ensembl.org/id/ENSGALT00010036959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021513.1", "url": "https://www.ensembl.org/id/ENSGALP00010021513.1" } ] } }, { "isoform_ac": "A0A8V0YYT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT6/entry", "sequence": { "sequence": "MGKVQKGRAVDLIVLVWGSSPATNSLKVKVENQYDFRDIASIIAMAKTYATSEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTERYRLWVDACAEMFGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRQLIADLVVSKMTQLVSTAGSTPSPLRPWPPQVQPQTVKTQPGPQLAQLSQPRPPPQGGPRQPQASQPPRTNAPPQQRLSPQGQQPQSPLSTSPQQQRSPGSPQQVRSATGSSPVQASKAGVFPPQQPRPPAQGRAPSQPSPTETSKQQATPQPHLNKSQSLTNTFSISESSQRGNASEDEAKAETIRNLRKSFASLFSD", "length": 350, "header": "tr|A0A8V0YYT6-1|A0A1D5PMP8_CHICK Computationally mapped isoform of Synapsin III OS=Gallus gallus OX=9031 GN=SYN3 PE=3 SV=1 CANONICAL=A0A1D5PMP8-1" }, "locus": { "chromosome": "1", "start_pos": 53269516, "end_pos": 53238542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036955.1", "url": "https://www.ensembl.org/id/ENSGALT00010036955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021509.1", "url": "https://www.ensembl.org/id/ENSGALP00010021509.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857420", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857420", "resource": "KEGG Pathway" }, { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "O14994-1", "protein_name": "Synapsin-3", "gene_name": "SYN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD", "length": 580 }, "evidence": [ { "id": "A0A1D5PMP8", "url": "https://omabrowser.org/oma/group/A0A1D5PMP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70441-1", "protein_name": "Synapsin-3", "gene_name": "Syn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFSSAMKQTPQAPTGLMEPPTPVTPVVQRPRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKNGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPGASVPSPLRPWGPQTKSAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPPRSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPTASLSSHTRPPVQGRSTSQQGEEPQKTASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETIRNLRKSFASLFSD", "length": 579 }, "evidence": [ { "id": "A0A1D5PMP8", "url": "https://omabrowser.org/oma/group/A0A1D5PMP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8JZP2-1", "protein_name": "Synapsin-3", "gene_name": "Syn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFSGAMKQTPQAPSGLMEPPTPVTPVVQRPRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPGATVPSPLRPWGPQTKPAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPPRSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPSASLSSHNRPPVQGRSTSQQGEEPQKSASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETIRNLRKSFASLFSD", "length": 579 }, "evidence": [ { "id": "A0A1D5PMP8", "url": "https://omabrowser.org/oma/group/A0A1D5PMP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" }, { "id": "PF02750", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02750" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synapsin ATP-binding", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 396, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP8" }, { "id": "PF02078", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02078" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synapsin pre-ATP-grasp", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 190, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 30, "end_pos": 32 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PSK5-1", "uniprot_ac": "A0A1D5PSK5", "uniprot_id": "A0A1D5PSK5_CHICK", "mass": { "chemical_mass": 31493.0, "monoisotopic_mass": 31493.0 }, "refseq": { "ac": "XP_004937237", "name": "cell cycle checkpoint protein RAD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937237" }, "gene_names": [ { "name": "RAD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ] }, { "name": "RAD1", "type": "synonym", "evidence": [ { "id": "XP_004937237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937237" } ] } ], "protein_names": [ { "name": "Cell cycle checkpoint protein RAD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5/entry#names_and_taxonomy" } ] }, { "name": "cell cycle checkpoint protein RAD1", "type": "synonym", "evidence": [ { "id": "XP_004937237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937237" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937237" } ] }, { "annotation": "Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5#function" }, { "database": "UniProtKB", "id": "ARBA00055414", "url": "https://www.uniprot.org/uniprotkb/ARBA00055414#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5", "locus": { "chromosome": "Z", "start_pos": 11104616, "end_pos": 11119284, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013238", "url": "https://www.ensembl.org/id/ENSGALG00010013238" } ] } } ], "crossref": [ { "id": "A0A1D5PSK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PSK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003365", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003365", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427432", "url": "https://www.ncbi.nlm.nih.gov/gene/427432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427432", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427432", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSQAYKF", "url": "https://omabrowser.org/oma/group/WSQAYKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSK5", "url": "https://www.orthodb.org/?gene=A0A1D5PSK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL63", "url": "https://www.orthodb.org/?gene=A0A8V0YL63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR33", "url": "https://www.orthodb.org/?gene=A0A8V0YR33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10870:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10870:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-176187", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5685938", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFSTQSPASGEQYVLTASLDNARNLSSLLRAVHFQDHATCFATANGLRVTVEDAKCIQANAFIQAEIFQEFHVQEESVMFRINLAVFLDCLTIFGASSLPGTSTALRMCYRGYGHPLMLFLEEGGVVTVCRINTQEPEDLLDFNFCSTNVVNKIILQSDGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSAHLDYPKDSDLMEAFHCNQTQTNRYKISLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPNEEITEAEL", "length": 281, "header": "tr|A0A1D5PSK5-1|A0A1D5PSK5_CHICK Isoform 1 of Cell cycle checkpoint protein RAD1 OS=Gallus gallus OX=9031 GN=RAD1 PE=3 SV=1 CANONICAL=A0A1D5PSK5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PSK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5/entry", "sequence": { "sequence": "MPFSTQSPASGEQYVLTASLDNARNLSSLLRAVHFQDHATCFATANGLRVTVEDAKCIQANAFIQAEIFQEFHVQEESVMFRINLAVFLDCLTIFGASSLPGTSTALRMCYRGYGHPLMLFLEEGGVVTVCRINTQEPEDLLDFNFCSTNVVNKIILQSDGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSAHLDYPKDSDLMEAFHCNQTQTNRYKISLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPNEEITEAEL", "length": 281, "header": "tr|A0A1D5PSK5-1|A0A1D5PSK5_CHICK Isoform 1 of Cell cycle checkpoint protein RAD1 OS=Gallus gallus OX=9031 GN=RAD1 PE=3 SV=1 CANONICAL=A0A1D5PSK5-1" }, "locus": { "chromosome": "Z", "start_pos": 11119188, "end_pos": 11113888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031800.1", "url": "https://www.ensembl.org/id/ENSGALT00010031800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018617.1", "url": "https://www.ensembl.org/id/ENSGALP00010018617.1" } ] } }, { "isoform_ac": "A0A8V0YL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL63/entry", "sequence": { "sequence": "MPFSTQSPASGEQYVLTASLDNARNLSSLLRAVHFQDHATCFATANGLRVTVEDAKCIQANAFIQAEIFQEFHVQEESVMFRINLAVFLDCLTIFGASSLPGTSTALRMCYRGYGHPLMLFLEEGGVVTVCRINTQEPEDLLDFNFCSTNVVNKIILQSDGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSAHLDYPKDSDLMEAFHCNQTQTNSRGIKNKKSSFVNSPATVPQPRHRKKAESSINLQKPDITHVKAVL", "length": 265, "header": "tr|A0A8V0YL63-1|A0A1D5PSK5_CHICK Computationally mapped isoform of Cell cycle checkpoint protein RAD1 OS=Gallus gallus OX=9031 GN=RAD1 PE=3 SV=1 CANONICAL=A0A1D5PSK5-1" }, "locus": { "chromosome": "Z", "start_pos": 11119188, "end_pos": 11113626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031803.1", "url": "https://www.ensembl.org/id/ENSGALT00010031803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018620.1", "url": "https://www.ensembl.org/id/ENSGALP00010018620.1" } ] } }, { "isoform_ac": "A0A8V0YR33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR33/entry", "sequence": { "sequence": "MPFSTQSPASGEQYVLTASLDNARNLSSLLRAVHFQDHATCFATANGLRVTVEDAKCIQANAFIQAEIFQEFHVQEESVMFRINLAVFLDCLTIFGASSLPGTSTALRMCYRGYGHPLMLFLEEGGVVTVCRINTQEPEDLLDFNFCSTNVVNKIILQSDGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSAHLDYPKDSDLMEAFHCNQTQTNRDTKAEKHFWTGLCHMQGTCCVRARCAKMSTRAASPATTGERFGSAGRAEQPRGSSSLQPSTAVDVGAARLRGQPKA", "length": 297, "header": "tr|A0A8V0YR33-1|A0A1D5PSK5_CHICK Computationally mapped isoform of Cell cycle checkpoint protein RAD1 OS=Gallus gallus OX=9031 GN=RAD1 PE=3 SV=1 CANONICAL=A0A1D5PSK5-1" }, "locus": { "chromosome": "Z", "start_pos": 11119188, "end_pos": 11104618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031807.1", "url": "https://www.ensembl.org/id/ENSGALT00010031807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018623.1", "url": "https://www.ensembl.org/id/ENSGALP00010018623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427432", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427432", "resource": "KEGG Pathway" }, { "id": "R-GGA-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-GGA-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-GGA-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZC52-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "Rad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLLTQYNEDEYEQYCLVASLDNVRNLSTVLKAIHFKEHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFIIQEESVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLEEGGVVTVCKITTQEPEDTLDFDFCSTNVMNKIILQSEGLREAFSELDMTGDVLQITVSPDKPYFRLSTFGNAGNSHLDYPKDSDLVEAFHCNKTQINRYKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPES", "length": 280 }, "evidence": [ { "id": "A0A1D5PSK5", "url": "https://omabrowser.org/oma/group/A0A1D5PSK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SND5-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLLTQQIPDESDYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFTVQEESVTFRINLTVLLDCLSIFGSSPVPGTLTALRMCYQGYGYPLMLFLEEGGVVTVCKINTQEPEETLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSSHLDYPKDSDLMESFHCNQTQVNRYKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPESES", "length": 281 }, "evidence": [ { "id": "A0A1D5PSK5", "url": "https://omabrowser.org/oma/group/A0A1D5PSK5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFKVQEESVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLMLFLEEGGVVTVCKINTQEPEETLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSSHLDYPKDSDLMEAFHCNQTQVNRYKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPESES", "length": 282 }, "evidence": [ { "id": "A0A1D5PSK5", "url": "https://omabrowser.org/oma/group/A0A1D5PSK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QWZ1-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "Rad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLLTQYNEEEYEQYCLVASLDNVRNLSTVLKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFVIQEESVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLEEGGVVTVCKITTQEPEETLDFDFCSTNVMNKIILQSEGLREAFSELDMTGDVLQITVSPDKPYFRLSTFGNAGNSHLDYPKDSDLVEAFHCDKTQVNRYKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPES", "length": 280 }, "evidence": [ { "id": "A0A1D5PSK5", "url": "https://omabrowser.org/oma/group/A0A1D5PSK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQD4-1", "protein_name": "DNA repair protein Rad1", "gene_name": "Rad1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDVEPSPYGDCKFVARVEHIKTFIQAIKSICFNDYGMVQVSEDGLRITVEQGKSIQATLFMPPGAFMEFRVQDFQCFGVKMNVLSECLSLFGSADCSLRMMYRDKGDPLKIILYPHDDDDVSTECAIKTMDCDEPIDYDQNLKDPDLNVIFVRGPNLSKVFNELEKSAEEFEFVTSPNRPHFKITTVGIMQAVFSVEVAKTSPMMMMFNCKQTVVARYKSQQIRMTNKAMQSATKVAIKTNSVGLLELHLVMQGDSQEEIFIQFFIIPLLNTD", "length": 274 }, "evidence": [ { "id": "A0A1D5PSK5", "url": "https://omabrowser.org/oma/group/A0A1D5PSK5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" }, { "name": "checkpoint clamp complex", "id": "GO:0030896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030896", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" }, { "name": "meiotic recombination checkpoint signaling", "id": "GO:0051598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051598", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" }, { "name": "cellular response to ionizing radiation", "id": "GO:0071479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSK5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PXZ3-1", "uniprot_ac": "A0A1D5PXZ3", "uniprot_id": "A0A1D5PXZ3_CHICK", "mass": { "chemical_mass": 56233.0, "monoisotopic_mass": 56233.0 }, "refseq": { "ac": "XP_015146666", "name": "patatin-like phospholipase domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146666" }, "gene_names": [ { "name": "PNPLA3", "type": "recommended", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ] }, { "name": "PNPLA3", "type": "synonym", "evidence": [ { "id": "XP_015146666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146666" } ] } ], "protein_names": [ { "name": "triacylglycerol lipase", "type": "recommended", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.3", "type": "synonym", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3/entry#names_and_taxonomy" } ] }, { "name": "patatin-like phospholipase domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146666" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146666", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146666" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PNPLA3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3", "locus": { "chromosome": "1", "start_pos": 69173375, "end_pos": 69155961, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013267", "url": "https://www.ensembl.org/id/ENSGALG00010013267" } ] } } ], "crossref": [ { "id": "A0A1D5PXZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029308", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418233", "url": "https://www.ncbi.nlm.nih.gov/gene/418233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMSYVML", "url": "https://omabrowser.org/oma/group/VMSYVML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXZ3", "url": "https://www.orthodb.org/?gene=A0A1D5PXZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLD7", "url": "https://www.orthodb.org/?gene=A0A8V0YLD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRA2", "url": "https://www.orthodb.org/?gene=A0A8V0YRA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1482883", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482883", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146666", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146666", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDRERGWSVSFAGCGFLGVYHIGAATCLQEYAPHIIRDARHIYGASAGALAGAVLVGGGSLAEACADVLALAKEARKRNLGPLHPSFNVIKIIRDGLMRNLPENTHLLSSGRLCISLTRVSDGKNTLISNFNSKEEVVQALICSSFVPIYCGLIPPSFRGVRYVDGGISDNLPQYESKNTITVSPFAGECDICPKGNSANFHEMNVTNTSIQLSLGNLYRLTQALFPPEPKVLGEICEQGYSDAFKFLKENGILNDSIYVSLSFTKTNPHEAAQHIDYMKKRNKSENSRMETSQVEVLGEQMKQNPWPLEKSIFESLPPRLRKALQEACKEPNGFYAQFSKLFPVRVISYLMLPYTLPVESAYSAALRLVNWFPDMPADVRWMQEQLLQIAGTVYSQAKKRLFCTSRKDNYTALRKCQTAPATVEFHSSYCHLKMPHSSADIETWLWESSCYMDSVMKHTSPKTKEQSDLNSYPNFLPNSDESGLEIDFDSSSETSFQTAPEY", "length": 504, "header": "tr|A0A1D5PXZ3-1|A0A1D5PXZ3_CHICK Isoform 1 of triacylglycerol lipase OS=Gallus gallus OX=9031 GN=PNPLA3 PE=1 SV=2 CANONICAL=A0A1D5PXZ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3/entry", "sequence": { "sequence": "MLDRERGWSVSFAGCGFLGVYHIGAATCLQEYAPHIIRDARHIYGASAGALAGAVLVGGGSLAEACADVLALAKEARKRNLGPLHPSFNVIKIIRDGLMRNLPENTHLLSSGRLCISLTRVSDGKNTLISNFNSKEEVVQALICSSFVPIYCGLIPPSFRGVRYVDGGISDNLPQYESKNTITVSPFAGECDICPKGNSANFHEMNVTNTSIQLSLGNLYRLTQALFPPEPKVLGEICEQGYSDAFKFLKENGILNDSIYVSLSFTKTNPHEAAQHIDYMKKRNKSENSRMETSQVEVLGEQMKQNPWPLEKSIFESLPPRLRKALQEACKEPNGFYAQFSKLFPVRVISYLMLPYTLPVESAYSAALRLVNWFPDMPADVRWMQEQLLQIAGTVYSQAKKRLFCTSRKDNYTALRKCQTAPATVEFHSSYCHLKMPHSSADIETWLWESSCYMDSVMKHTSPKTKEQSDLNSYPNFLPNSDESGLEIDFDSSSETSFQTAPEY", "length": 504, "header": "tr|A0A1D5PXZ3-1|A0A1D5PXZ3_CHICK Isoform 1 of triacylglycerol lipase OS=Gallus gallus OX=9031 GN=PNPLA3 PE=1 SV=2 CANONICAL=A0A1D5PXZ3-1" }, "locus": { "chromosome": "1", "start_pos": 69171683, "end_pos": 69156057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031896.1", "url": "https://www.ensembl.org/id/ENSGALT00010031896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018698.1", "url": "https://www.ensembl.org/id/ENSGALP00010018698.1" } ] } }, { "isoform_ac": "A0A8V0YLD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD7/entry", "sequence": { "sequence": "MLDRERGWSVSFAGCGFLGVYHIGAATCLQEYAPHIIRDARHIYGASAGALAGAVLVGGGSLGRRESSLLRDVWCKGERQGRSWNMGNSEQILENTAEACADVLALAKEARKRNLGPLHPSFNVIKIIRDGLMRNLPENTHLLSSGRLCISLTRVSDGKNTLISNFNSKEEVVQALICSSFVPIYCGLIPPSFRGVRYVDGGISDNLPQYESKNTITVSPFAGECDICPKGNSANFHEMNVTNTSIQLSLGNLYRLTQALFPPEPKVLGEICEQGYSDAFKFLKENGILNDSIYVSLSFTKTNPHEAAQHIDYMKKRNKSENSRMETSQVEVLGEQMKQNPWPLEKSIFESLPPRLRKALQEACKEPNGFYAQFSKLFPVRVISYLMLPYTLPVESAYSAALRLVNWFPDMPADVRWMQEQLLQIAGTVYSQAKKRLFCTSRKDNYTALRKCQTAPATVEFHSSYCHLKMPHSSADIETWLWESSCYMDSVMKHTSPKTKEQSDLNSYPNFLPNSDESGLEIDFDSSSETSFQTAPEY", "length": 538, "header": "tr|A0A8V0YLD7-1|A0A1D5PXZ3_CHICK Computationally mapped isoform of triacylglycerol lipase OS=Gallus gallus OX=9031 GN=PNPLA3 PE=1 SV=1 CANONICAL=A0A1D5PXZ3-1" }, "locus": { "chromosome": "1", "start_pos": 69171683, "end_pos": 69156057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031893.1", "url": "https://www.ensembl.org/id/ENSGALT00010031893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018695.1", "url": "https://www.ensembl.org/id/ENSGALP00010018695.1" } ] } }, { "isoform_ac": "A0A8V0YRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA2/entry", "sequence": { "sequence": "MLDRERGWSVSFAGCGFLGVYHIGAATCLQEYAPHIIRDARHIYGASAGALAGAVLVGGGSLAEACADVLALAKEARKRNLGPLHPSSGRLCISLTRVSDGKNTLISNFNSKEEVVQALICSSFVPIYCGLIPPSFRGVRYVDGGISDNLPQYESKNTITVSPFAGECDICPKGNSANFHEMNVTNTSIQLSLGNLYRLTQALFPPEPKVLGEICEQGYSDAFKFLKENGILNDSIYVSLSFTKTNPHEAAQHIDYMKKRNKSENSRMETSQVEVLGEQMKQNPWPLEKSIFESLPPRLRKALQEACKEPNGFYAQFSKLFPVRVISYLMLPYTLPVESAYSAALRLVNWFPDMPADVRWMQEQLLQIAGTVYSQAKKRLFCTSRKDNYTALRKCQTAPATVEFHSSYCHLKMPHSSADIETWLWESSCYMDSVMKHTSPKTKEQSDLNSYPNFLPNSDESGLEIDFDSSSETSFQTAPEY", "length": 481, "header": "tr|A0A8V0YRA2-1|A0A1D5PXZ3_CHICK Computationally mapped isoform of triacylglycerol lipase OS=Gallus gallus OX=9031 GN=PNPLA3 PE=1 SV=1 CANONICAL=A0A1D5PXZ3-1" }, "locus": { "chromosome": "1", "start_pos": 69171683, "end_pos": 69156057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031891.1", "url": "https://www.ensembl.org/id/ENSGALT00010031891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018693.1", "url": "https://www.ensembl.org/id/ENSGALP00010018693.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418233", "resource": "KEGG Pathway" }, { "id": "R-GGA-1482883", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482883", "resource": "Reactome", "description": "Acyl chain remodeling of DAG and TAG" }, { "id": "R-GGA-163560", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z9J9-1", "protein_name": "Acylglycerol transacylase", "gene_name": "Pnpla3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYDPERRWSLSFAGCGFLGFYHIGATLCLSERAPHILREARTFFGCSAGALHAVTFVCSLPLDHIMEILMDLVRKARSRNIGTLHPFFNINKCVRDGLQETLPDNVHQIISGKVYISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFLQVNITNLSLRLCTGNLHLLTRALFPSDVKVMGELCFQGYLDAFRFLEENGICNGPQRSLSLSLEKEMAPETMIPCLENGHLVAGNKVPVSCVCLTAVPSDESIWEMLSPKLSTALTEAIKDRGGYLNKVCNLLPIRILSYILLPCTLPVESAIAAVHRLVMWLPDIHEDIQWLQWATSQVCARMTMCLLPSTRSRASKDNHQTLKHGYHPSLHKPQGSSAGL", "length": 425 }, "evidence": [ { "id": "A0A1D5PXZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PXZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LTE6-1", "protein_name": "Acylglycerol transacylase", "gene_name": "PNPLA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYDSERGWSLSFVGCGFLGFYHVGVTRCLCERAPHLIRHAHRFFGTSAGALHCAVFLSGTSLDQTLEMLMGLVRSARSRSLSILHPSFNLSKRLREGLRRILPDNAHQLLSGKLCISLTRVSDGKNVLVSDFRSKEEVLDALLCSSFIPLVSGFIPPSFRGERYVDGGVSDNVPFFDSKTTITVSPFYGENDICPKVKSTNFLHVDFTKLNLRLCSENIYLISRALFPPDVKVLGEICLRGYLDAVRFLEENGICDRPYPGLNVSLAEWDVFEPPWEPLSPDSSPGVAAWEARPEGDELLDHLRLSILPWDEHIRILSPKLMLALREAARNPDGYISKMCNFLPIKVVSYMLLPCTLPLESAIAVVQRLVMWLPDMPDDIQWLQWATSRICCRVMRCLLPTSRSQTPANGHQPPPTNQNTRGAASLPIPPWTRTPTPWTGQ", "length": 441 }, "evidence": [ { "id": "A0A1D5PXZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PXZ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q91WW7-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase Pnpla3", "gene_name": "Pnpla3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTRSRASKDDHRMLKHGHHPSPHKPQGNSAGL", "length": 413 }, "evidence": [ { "id": "A0A1D5PXZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PXZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NST1-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase PNPLA3", "gene_name": "PNPLA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLCKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFIPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL", "length": 481 }, "evidence": [ { "id": "A0A1D5PXZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PXZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "positive regulation of triglyceride catabolic process", "id": "GO:0010898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010898", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "triglyceride acyl-chain remodeling", "id": "GO:0036153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036153", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA binding", "id": "GO:0036042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036042", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "mono-olein transacylation activity", "id": "GO:0051264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051264", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "diolein transacylation activity", "id": "GO:0051265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051265", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "lysophosphatidic acid binding", "id": "GO:0035727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035727", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482647" } ] }, { "id": "R-GGA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482654", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482654" } ] }, { "id": "R-GGA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482777", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482777" } ] }, { "id": "R-GGA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1498728" ], "enzyme_list": [ "A0A1D5PXZ3-1", "A0A8V1A948-1" ], "evidence": [ { "id": "R-GGA-1482811", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482811" } ] }, { "id": "R-GGA-8848339", "name": "PNPLA5 hydrolyzes TAG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXZ3-1" ], "evidence": [ { "id": "R-GGA-8848339", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8848339" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498728", "participant_name": "2-MAG [endoplasmic reticulum membrane]", "crossref": [ { "id": "17389", "database": "ChEBI", "url": "" }, { "id": "C02112", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PXZ3", "gene_name": "PNPLA3", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5PXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940325" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM184A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2", "locus": { "chromosome": "3", "start_pos": 62403869, "end_pos": 62340535, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015017", "url": "https://www.ensembl.org/id/ENSGALG00010015017" } ] } } ], "crossref": [ { "id": "A0A1D5PFG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014881", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014881", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421727", "url": "https://www.ncbi.nlm.nih.gov/gene/421727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421727", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCKKVAQ", "url": "https://omabrowser.org/oma/group/MCKKVAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P4W7", "url": "https://www.orthodb.org/?gene=A0A1D5P4W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFG2", "url": "https://www.orthodb.org/?gene=A0A1D5PFG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM0", "url": "https://www.orthodb.org/?gene=A0A8V0YQM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQP6", "url": "https://www.orthodb.org/?gene=A0A8V0YQP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N961", "url": "https://www.orthodb.org/?gene=F1N961", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P4W7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P4W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N961", "url": "https://www.uniprot.org/uniprotkb/F1N961", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N961-1", "url": "https://www.uniprot.org/uniprotkb/F1N961-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQIRMHEQDLSKKHEKELDVLTADHIREKQSMLADFNKTQELLKEINSALQVSLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIEDKKFYQLELVNRETNYNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESSGVGNGHPNRLDPIPNSPIHDIEFNSSKPLPQPIPPKEPKTFLSPPQTDASPVASPDPQRQEWLARYFTF", "length": 1141, "header": "tr|A0A1D5PFG2-1|A0A1D5PFG2_CHICK Isoform 1 of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=1 CANONICAL=A0A1D5PFG2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P4W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W7/entry", "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQISLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIEDKKFYQLELVNRETNYNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESSGVGNGHPNRLDPIPNSPIHDIEFNSSKPLPQPIPPKEPKTFLSPPQTDASPVASPDPQRQEWLARYFTF", "length": 1092, "header": "tr|A0A1D5P4W7-1|A0A1D5P4W7_CHICK Computationally mapped isoform of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=2 CANONICAL=A0A1D5PFG2-1" }, "locus": { "chromosome": "3", "start_pos": 62402254, "end_pos": 62340744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036114.1", "url": "https://www.ensembl.org/id/ENSGALT00010036114.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020976.1", "url": "https://www.ensembl.org/id/ENSGALP00010020976.1" } ] } }, { "isoform_ac": "A0A1D5PFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2/entry", "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQIRMHEQDLSKKHEKELDVLTADHIREKQSMLADFNKTQELLKEINSALQVSLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIEDKKFYQLELVNRETNYNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESSGVGNGHPNRLDPIPNSPIHDIEFNSSKPLPQPIPPKEPKTFLSPPQTDASPVASPDPQRQEWLARYFTF", "length": 1141, "header": "tr|A0A1D5PFG2-1|A0A1D5PFG2_CHICK Isoform 1 of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=1 CANONICAL=A0A1D5PFG2-1" }, "locus": { "chromosome": "3", "start_pos": 62402254, "end_pos": 62340744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036121.1", "url": "https://www.ensembl.org/id/ENSGALT00010036121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020980.1", "url": "https://www.ensembl.org/id/ENSGALP00010020980.1" } ] } }, { "isoform_ac": "A0A8V0YQM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM0/entry", "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQRHCLGEALHKSISNISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQIRMHEQDLSKKHEKELDVLTADHIREKQSMLADFNKTQELLKEINSALQVSLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIEDKKFYQLELVNRETNYNKVFNASPNVGVINPLVKQKKKNDKSTNRFVSVPNLSALESSGVGNGHPNRLDPIPNSPIHDIEFNSSKPLPQPIPPKEPKTFLSPPQTDASPVASPDPQRQEWLARYFTF", "length": 1155, "header": "tr|A0A8V0YQM0-1|A0A1D5PFG2_CHICK Computationally mapped isoform of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=1 CANONICAL=A0A1D5PFG2-1" }, "locus": { "chromosome": "3", "start_pos": 62402254, "end_pos": 62340744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036118.1", "url": "https://www.ensembl.org/id/ENSGALT00010036118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020978.1", "url": "https://www.ensembl.org/id/ENSGALP00010020978.1" } ] } }, { "isoform_ac": "A0A8V0YQP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP6/entry", "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQRHCLGEALHKSISNISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQIRMHEQDLSKKHEKELDVLTADHIREKQSMLADFNKTQELLKEINSALQVSLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIQKKKNDKSTNRFVSVPNLSALESSGVGNGHPNRLDPIPNSPIHDIEFNSSKPLPQPIPPKEPKTFLSPPQTDASPVASPDPQRQEWLARYFTF", "length": 1120, "header": "tr|A0A8V0YQP6-1|A0A1D5PFG2_CHICK Computationally mapped isoform of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=1 CANONICAL=A0A1D5PFG2-1" }, "locus": { "chromosome": "3", "start_pos": 62402254, "end_pos": 62340744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036106.1", "url": "https://www.ensembl.org/id/ENSGALT00010036106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020969.1", "url": "https://www.ensembl.org/id/ENSGALP00010020969.1" } ] } }, { "isoform_ac": "F1N961-1", "url": "https://www.uniprot.org/uniprotkb/F1N961/entry", "sequence": { "sequence": "MATPGMSWQQQHGYGGGSAPGAGKFSSGSAPSGLGAEHSPDLHFKMSKKIAQLTKVIYALNTKNDEHEAAIQALKDAHEEEIQQILAETREKILQYKSKVAEEMDLKRKIQVLEESLEDHKKMKHQALTEFEAYKDRVEDMQLCAEAQHVQRVVTMSREVEEIRKKFEERLRSFIQLQVQYEKDKRSALEDLRAAHRLEIQELLKTQQNQNATLSKGQEKLEELHRLELEDLNNKVEELRLERKKLIEDYEGKLSKAQSFYEHELDSLKRSQLFTAESLHACKEKEVELRKEFQNQESILRKNLGKLKTELQMVQDEAASLREKCQKLQVALSTAENNVQVLQKQLDDVKEEEMSLLSKHKEVESELAAARERLQQQATDLVLKASHIGMLQATQMTQEVTIRDLESEKSRLKEKLSQLEEERNLLQSKTQSLDERQRQQILALEKKVNEARETQREYYEKELVKLQARLEGEAAQLKEAHSKTLEELAWKHHTAIEAAHSNANKDKKKLQMELEQQFEKEKLHLEDDKNQLRQQLENLREELTTKLTSANQEVCRLQDLVRKSEQGLGTAEGHISSLQEAQEILQKELELTRARLRETTDSLYNVEGELDQERQQHEVMIAAMREEEKFKVDRMARDLEIKWTENLRQECNKLREELRLQHEEDKKAAMTQLLQLKEREKNAARDGWQKKVEDLLDQISLLKQNLEMQLSQSQSSLQQLQAQFSQERQRLTQEIQELEEEHQQRHKSLQEAHILAFQNMEETKEQEQKELEERLQQKHSEELQALKETHKQAMEGFKLEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDQLRHNHQQELLAAKMELERSIELGRRQEKEFLCRISDLQDELRHRDHHIAELDKEILHLHDNISALTKELEFKGKEVLRIRSESNQQIRMHEQDLSKKHEKELDVLTADHIREKQSMLADFNKTQELLKEINSALQVSLEEMEEKYKNRESRPEDLQLISELKDLIAERDQLIKKLIEDKKFYQLELVNRETNYNKVFNASPNVGVINPLVKPSSD", "length": 1052, "header": "tr|F1N961-1|A0A1D5PFG2_CHICK Computationally mapped isoform of Family with sequence similarity 184 member A OS=Gallus gallus OX=9031 GN=FAM184A PE=4 SV=4 CANONICAL=A0A1D5PFG2-1" }, "locus": { "chromosome": "3", "start_pos": 62402187, "end_pos": 62340744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036104.1", "url": "https://www.ensembl.org/id/ENSGALT00010036104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020967.1", "url": "https://www.ensembl.org/id/ENSGALP00010020967.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421727", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JNE4-1", "protein_name": "Family with sequence similarity 184 member A", "gene_name": "FAM184A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATPGMSWQQHYYGGSAAGAAKFPPSPAAAHQAGHSMDYSQDLHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSRVTEELDLKRKIQVLEASLEDHVKMKQAALAEFEAYKHRIEDMQLCAEAQHVQRIVTMSREVEEIRRKFEERLRSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVEALNQTLEELRLERKKLIEDYEGKLHKAQSFYEHELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLRDKCQKLQLALVTAENNVQVLQKQLDDAKEGEMALLSRHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSKANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVNEAKKTQQEYYEMELKDLQNRLEGEMAQLNEAHSKTLEELAWKHHMAIEAVHSNVIRDKKKLQMELEEQYKKEKLNLEEDKNQLQQELENLKEEMEDKLNSANQEIGRLQDIVSKSEQGLGSAEGLIASLQDSQDRLQNELELTKGRLRETKDALLNVEGELEQERQQHEEILAAMKEEEKLRVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAAKDSWQKKVEDLLNQISLLKQNLEMQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHMCRITDLQDEVRHREHHISDLDKEVQHLHENISALTKELEFKGKEILRIRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMIAELKAMLTERDQVIKKLIEDNKFYQLELINRETNFNKVFNSSPTVGVINPLTKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPNRLDPIPNSPVHDIEFNSSKPLPQPVPPKEPKTFLSPPQSEASPAASPDPQRQEWFARYFTF", "length": 1143 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZS46-1", "protein_name": "Family with sequence similarity 184, member A", "gene_name": "Fam184a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPGMSWQHHYYGGSSSGPAKFTTSPAAAQLAGHNMDYSQDMHLKMSKKIAQLTKVIYALNTKNDEHDSAIQALKDAHEEEIQQILAETREKILLYKSRVTEELDLKRKIQVLEASLEDHVKMKQEALKEFEAYKRRVEDMQLCAEAQHVQRIVTMSREVEEIRKKFEERLRSFGQLQVQFENDKQSALEELRTTHRLEVQELLRSQEDHSASMNLGQEKAEELHRREVEALNNTLEELRLEKKELIEEYEGKLSKAQLFYERELDNLKRSQLFTAESLQASRDKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEASSLLDKCQKLQMALATAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQEQASDLVRKASHIGMLQATQMTQEVTIKDLESEKSRAHERLCQLEKERAFLQSRTQSLDEEQKQQELEMEKKVNEVKRTQQEYYEMELKNLQTRLEGEVAQLNETHGKTLEELAWKHHMAIEAVHSNASRDKIKLQTELEEQHKKEKLSLEEDKNQLQLELENLKQALGDKLTSANQEIDRLQDLVRKSEQGLGSAEGLIASLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHDLEIKWTENLRQECSKLRQELKLQHEEDKKCAMSQLLQLKEREKTAARDSWQKKVEDLLNQRHSLGEALHKSINNISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHATSIDLLRHSHHQELAAAKMELERSIDISRRQSKEHMCRISDLQDELRHREHHITDLDKEVQHLHESISTLTKELELKGKEILRIRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDLQMIAELKSLLTERDQVIKKLIQKKKNDKSPANRFVSVPNLSALESGGMGNGHPTRLEPIPNSPAHDVEFNSNKPLPQPLPPKEPKTFLSPPQSEASPVASPDPQRQEWFARYFTF", "length": 1122 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BA11-1", "protein_name": "Family with sequence similarity 184 member A", "gene_name": "FAM184A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATPGMSWQQHYYGGSAAKFVPSPAAGQQAGHCMDYSQDMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSRVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEERLRSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKCQQDHSASVNKGQEKAEELHRMEVEALNKTLEELRLERKKLVEDYEGKLHKAQSFYEHELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLRDKCQKLQIALVTAENNVQVLQKQLDDAKEGEMALLSRHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVNEAKKTQQEYYEMELKNLQSRLEGEVAQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQYKKEKLNLEEDKNQLQQELENLKEELENKLHSANQEIGRLQEMVSKSEQGLGSAEGLIASLQDSQERLQNELDLTKGRLKETKDALLNVESKLEQERRQHEETLAAMKEEEKLQVDRMAHDLEMKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLEMQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALESHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNQQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHMCRITDLQDEVRHREHHISDLDKEVQHLHENINALTKELEFKGKEILRIRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEVNAALQVSLEEMEEKYLMRESKPEDIQMIAELKAMLTERDQVIKKLMEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLMKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPNRLDPIPNSPVHDIEFNSSKPLPQPVPPKEPKTFLRYH", "length": 1116 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PW83-1", "protein_name": "Family with sequence similarity 184, member A", "gene_name": "Fam184a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPGMSWQHHYYGSSTSGPAKFATSPAAAQLAGHNMDYSQDMHLKMSKKIAQLTKVIYALNTRNDEHDAAIQALKDAHEEEIQQILAETREKILLYKSKVTEELDLRRKIQVLEASLEDHMKMKQEALTEFEAYKRRVEDMQLCAEAQHVQRIVTMSREVEEIRKKFEERLRSFGQLQVQFENDKQAALEDLRTTHRLEVQELLKSQQNHSSSVKLGQEKAEGLHRMEVEALNNTVKELRLEKKQLIEEYEGKLSKAQVFYERELDNLKRSQLFTAESLQASRDKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEASSLLDKCQKLQMALATAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQEQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLCQLEEERAFLQSRTQSLDEEQKQQVLELEKKVNEAKRTQQEYYEMELKNLQNRLEGEVAQLNEAHGKTLEELARKHHMAIEAVHSNASRDKIKLQTELEEQYKKEKLSLEEDKNQLQLELESLKQALGDKLTSANQEIGRLQDLVRKSEQGLGSAEGLISSLQDSQERLQSELDLTKGRLKETKDALLNVEAELQQERHEHEQTLATMKEEEKLRVDRMAHDLEIKWTENLRQECSKLRQELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALETHLQQKHSAELQSLKDAHRESMEGFRVEMEQELQTLRFELEDEGKAMLASLRSELNHQHAASIDLLRHSHHQELAAAKMELERSIDISRRQSKEHMCRISDLQEELRHREHHITDLDKEVQHLHENINTLTKELELKGKEILRVRSESNQQMRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEDMEEKYLMRESRPEDIQMIAELKSLITERDQVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSAANRFVSVPNLSALESSGMGNGHPTRLEPIPNSPAHDVEFNSNKPLPQPLPPKEPKTFLSPPQSEASPVASPDPQRQEWFARYFTF", "length": 1143 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SPS1-1", "protein_name": "Protein FAM184A isoform X1", "gene_name": "fam184ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATGAGWQHYYNPAGSASTGKYNSTSTSTSTSTSFPSGLTLEYTQDLHLKMSKKIAQLTKVIYALNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQYKSKISDEMDLKRRIQSLEESMELHERMKRQALDEFETYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQLQSQFEQEKRQALEELRSGHRQEVQELLRSHQSQNANYSKDQEKLGQLHKAEVDSLNERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEAALQKTLGKLRSELQRVQDEARESREKSHKLQASLMTAENNIKELHKQLEEVTKDAEIVEIRQREGECELEASRDRVQQQATEILLKASQIGSLQATQMTHEAVIRDLESEKSRLKDKVLRLEEERGALQNKCQTLDDRQRQQIVTLEKSLREEKQIYEKELMNLRAKYEDDTAHFKESHSRALEELSRKHRASLENIQSLSEKEKNRLLSDMEDQFNKERTSLEEQKRILREELDSLREELTAKLNMANNEVSRLQELVKQGEQTLGSSEGHISNLKDAQKKLLEELDATRARLRETSNLLTALQGEMETQKQQHDAKLISIKEEEKLKMDKMALELELKWTETLRQECKKLREELREDHEEDKRSALTQLAQNKDQELCSARESWQRKVEDLLEQISLLKQSLEMQLSQSQHSLQQLQAQFSQEREHLGQQLEEMEMEHQHRQQRLQEAHCCAIQDMQEARKHDLKALEERLRQQHHMELQTLREAHRQNIETLKQQSEQELQTLRFELEDEGKAMLASLRSELNHLHASAIEHMRQTHQQETAAAKQELENALEQSRVQERELLSRISDLQEEVSRRKKHIADLDHEIHTLNENISTLTKELELKGKEVLKIRSEANQQIRAHEQDLCKKHEREMAELNALHHRETQNMLSDFNKAQELLKDKISALQILLEGTEDKFRNRESRPEDLQTIAELKDMVAEREALVKKLVDDKKFYQLELVNRETSFNKIFNANPNVGVINPLVKQKRKNDKSATRFSSSANLRANVEASGTGSGQPQPNRLEPLPNSPIHQLEPNASKPLSLPTPLTEPKKVTSPPEGEESALTSPDPQRQEWFAQYFSF", "length": 1145 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8NB25-1", "protein_name": "Protein FAM184A", "gene_name": "FAM184A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGMSWQQHYYGGSAAKFAPSPATAQLAGHSMDYSQEMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSSPTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESGGVGNGHPNRLDPIPNSPVHDIEFNSSKPLPQPVPPKGPKTFLSPAQSEASPVASPDPQRQEWFARYFTF", "length": 1140 }, "evidence": [ { "id": "A0A1D5PFG2", "url": "https://omabrowser.org/oma/group/A0A1D5PFG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG2" }, { "id": "PF15665", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein FAM184A/B N-terminal", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 266, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 3 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1035, "end_pos": 1037 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1096, "end_pos": 1098 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 898, "end_pos": 900 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PEZ2-1", "uniprot_ac": "A0A1D5PEZ2", "uniprot_id": "A0A1D5PEZ2_CHICK", "mass": { "chemical_mass": 151309.0, "monoisotopic_mass": 151309.0 }, "refseq": { "ac": "XP_003640979", "name": "son of sevenless homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640979" }, "gene_names": [ { "name": "SOS1", "type": "recommended", "evidence": [ { "id": "A0A1D5PEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ] }, { "name": "SOS1", "type": "synonym", "evidence": [ { "id": "XP_003640979", "database": "RefSeq", "url": 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analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_003640979.2. 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"MQAQPLLYEFFSEENAPKWRGLLVPALKKVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1319, "header": "tr|A0A1D5PEZ2-1|A0A1D5PEZ2_CHICK Isoform 1 of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2/entry", "sequence": { "sequence": "MQAQPLLYEFFSEENAPKWRGLLVPALKKVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1319, "header": "tr|A0A1D5PEZ2-1|A0A1D5PEZ2_CHICK Isoform 1 of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16350016, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041698.1", "url": "https://www.ensembl.org/id/ENSGALT00010041698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024390.1", "url": "https://www.ensembl.org/id/ENSGALP00010024390.1" } ] } }, { "isoform_ac": "A0A8V0YTL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL6/entry", "sequence": { "sequence": "MGVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1292, "header": "tr|A0A8V0YTL6-1|A0A1D5PEZ2_CHICK Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16349392, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041680.1", "url": "https://www.ensembl.org/id/ENSGALT00010041680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024382.1", "url": "https://www.ensembl.org/id/ENSGALP00010024382.1" } ] } }, { "isoform_ac": "A0A8V0Z008-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z008/entry", "sequence": { "sequence": "MVAFKENDVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1298, "header": "tr|A0A8V0Z008-1|A0A1D5PEZ2_CHICK Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16344125, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041670.1", "url": "https://www.ensembl.org/id/ENSGALT00010041670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024374.1", "url": "https://www.ensembl.org/id/ENSGALP00010024374.1" } ] } }, { "isoform_ac": "A0A8V0Z1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1R0/entry", "sequence": { "sequence": "MSCWVFFDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1255, "header": "tr|A0A8V0Z1R0-1|A0A1D5PEZ2_CHICK Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16340547, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041654.1", "url": "https://www.ensembl.org/id/ENSGALT00010041654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024365.1", "url": "https://www.ensembl.org/id/ENSGALP00010024365.1" } ] } }, { "isoform_ac": "A0A8V0Z1T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1T1/entry", "sequence": { "sequence": "MAVWKNTWVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1298, "header": "tr|A0A8V0Z1T1-1|A0A1D5PEZ2_CHICK Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16342807, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041687.1", "url": "https://www.ensembl.org/id/ENSGALT00010041687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024386.1", "url": "https://www.ensembl.org/id/ENSGALP00010024386.1" } ] } }, { "isoform_ac": "A0A8V0Z7G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G5/entry", "sequence": { "sequence": "MMCSEMLLCLVTIILKHQKTKCYRGPQLLTKDSNPDVKLQEKEVQVQVHPKLSSTEDALQYVEELILQLLNMLCQAQPRSFLDVEDRVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDLSALTLSDEEPSTSGEQTYYDLVKSFMAEVRQYIRELNLIIRVFREPYASNSKLFSSHDVENIFSRISDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDMAEELAFDPYESYAQDILRPGFHDHFLSQLSKPGAAFYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYTQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYRHAFEIILKDENSVIFAAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRFPNPELYRFAEPDSEENIVFEENMQPKSGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGTVRGKAMKKWVESITKIINRKKQAQAIGPSHNITFESPPPAIEWHISKPGHTETFDLLTLHPIEIARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVIVVSRIIEILQVFQELNNFNGVLEIVSAMNSAAVYRLDHTFEQIPSRQKKILEEAYELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVEFDIRRFFENLNPMGSSMETEFTDYLFNKSLEIEPRNVKPPPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETETTASAPNSPRTPLTPPPASATSSTTDACSVFDSDPSSPFHARSASVSSISFTKTSDEAHVPPPVPPRRRPESAPAESSPSKITSAHLDSPPAIPPRQPTSKVYSPRYSVPDRTCISDPPESPPVLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNTFFPNSPSPFTPPPPQTPSPHVARRHLPSPPLIQQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLQNAHSS", "length": 1333, "header": "tr|A0A8V0Z7G5-1|A0A8V0Z7G5_CHICK Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=SOS1 PE=4 SV=1 CANONICAL=A0A1D5PEZ2-1" }, "locus": { "chromosome": "3", "start_pos": 16347237, "end_pos": 16309087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041710.1", "url": "https://www.ensembl.org/id/ENSGALT00010041710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024394.1", "url": "https://www.ensembl.org/id/ENSGALP00010024394.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431192", "resource": "KEGG Pathway" }, { "id": "R-GGA-112412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112412", "resource": "Reactome", "description": "SOS-mediated signalling" }, { "id": "R-GGA-1250347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1250347", "resource": "Reactome", "description": "SHC1 events in ERBB4 signaling" }, { "id": "R-GGA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-GGA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-GGA-167044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-167044", "resource": "Reactome", "description": "Signalling to RAS" }, { "id": "R-GGA-179812", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179812", "resource": "Reactome", "description": "GRB2 events in EGFR signaling" }, { "id": "R-GGA-180336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-180336", "resource": "Reactome", "description": "SHC1 events in EGFR signaling" }, { "id": "R-GGA-186763", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186763", "resource": "Reactome", "description": "Downstream signal transduction" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-1963640", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1963640", "resource": "Reactome", "description": "GRB2 events in ERBB2 signaling" }, { "id": "R-GGA-210993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210993", "resource": "Reactome", "description": "Tie2 Signaling" }, { "id": "R-GGA-2179392", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2179392", "resource": "Reactome", "description": "EGFR Transactivation by Gastrin" }, { "id": "R-GGA-2424491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2424491", "resource": "Reactome", 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"length": 1319 }, "evidence": [ { "id": "A0A1D5PEZ2", "url": "https://omabrowser.org/oma/group/A0A1D5PEZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": 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"id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEZ2" } ], "pmid": "" 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"A0A1L1RKF5-1", "uniprot_ac": "A0A1L1RKF5", "uniprot_id": "A0A1L1RKF5_CHICK", "mass": { "chemical_mass": 26593.0, "monoisotopic_mass": 26593.0 }, "refseq": { "ac": "XP_004939579", "name": "STARD3 N-terminal-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939579" }, "gene_names": [ { "name": "STARD3NL", "type": "recommended", "evidence": [ { "id": "A0A1L1RKF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ] }, { "name": "STARD3NL", "type": "synonym", "evidence": [ { "id": "XP_004939579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939579" } ] } ], "protein_names": [ { "name": "STARD3 N-terminal like", "type": "synonym", "evidence": [ { "id": "A0A1L1RKF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5/entry#names_and_taxonomy" } ] }, { "name": "STARD3 N-terminal-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004939579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939579" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STARD3NL", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5", "locus": { "chromosome": "2", "start_pos": 45955646, "end_pos": 45975879, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016137", "url": "https://www.ensembl.org/id/ENSGALG00010016137" } ] } } ], "crossref": [ { "id": "A0A1L1RKF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RKF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033038", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033038", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420730", "url": "https://www.ncbi.nlm.nih.gov/gene/420730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420730", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWWAVAI", "url": "https://omabrowser.org/oma/group/HWWAVAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RKF5", "url": "https://www.orthodb.org/?gene=A0A1L1RKF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUM0", "url": "https://www.orthodb.org/?gene=A0A8V0YUM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1C7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46121:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46121:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196108", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004939579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RKF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRVPNDAENAHSSSVESCPSLRDVHSINPTHLMARIESYDVREKKGISDVRRTFCLFVTFDLLFITLLWIIELNVKGGIETTLKKEVLHYDYSSSYFDIFLLAVFRFKVLILAYAMCRLRHWWAIAFTTAVTSAFLLAKVIISQLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRFLIAQGASERAALLHPGVLSDGQFYSPPESVAGSDEDSEEKQDSEKPVV", "length": 234, "header": "tr|A0A1L1RKF5-1|A0A1L1RKF5_CHICK Isoform 1 of STARD3 N-terminal like OS=Gallus gallus OX=9031 GN=STARD3NL PE=3 SV=2 CANONICAL=A0A1L1RKF5-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RKF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5/entry", "sequence": { "sequence": "MNRVPNDAENAHSSSVESCPSLRDVHSINPTHLMARIESYDVREKKGISDVRRTFCLFVTFDLLFITLLWIIELNVKGGIETTLKKEVLHYDYSSSYFDIFLLAVFRFKVLILAYAMCRLRHWWAIAFTTAVTSAFLLAKVIISQLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRFLIAQGASERAALLHPGVLSDGQFYSPPESVAGSDEDSEEKQDSEKPVV", "length": 234, "header": "tr|A0A1L1RKF5-1|A0A1L1RKF5_CHICK Isoform 1 of STARD3 N-terminal like OS=Gallus gallus OX=9031 GN=STARD3NL PE=3 SV=2 CANONICAL=A0A1L1RKF5-1" }, "locus": { "chromosome": "2", "start_pos": 45967168, "end_pos": 45956918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038802.1", "url": "https://www.ensembl.org/id/ENSGALT00010038802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022437.1", "url": "https://www.ensembl.org/id/ENSGALP00010022437.1" } ] } }, { "isoform_ac": "A0A8V0YUM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM0/entry", "sequence": { "sequence": "MNRVPNDAENAHSSSVESCPSLRDVHSINPTHLMARIESYDVREKKGISDVRRTFCLFVTFDLLFITLLWIIELNVKGGIETTLKKEVLHYDYSSSYFDIFLLAVFRFKVLILAYAMCRLRHWWAIAFTTAVTSAFLLAKVIISQLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENSKFLLSPSVTEVGNIWSPIVWQKNASFSFQKKFSCIKNLIMWHNFSRREHMPSVKWDFYLGR", "length": 246, "header": "tr|A0A8V0YUM0-1|A0A1L1RKF5_CHICK Computationally mapped isoform of STARD3 N-terminal like OS=Gallus gallus OX=9031 GN=STARD3NL PE=3 SV=1 CANONICAL=A0A1L1RKF5-1" }, "locus": { "chromosome": "2", "start_pos": 45967168, "end_pos": 45959517, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038808.1", "url": "https://www.ensembl.org/id/ENSGALT00010038808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022440.1", "url": "https://www.ensembl.org/id/ENSGALP00010022440.1" } ] } }, { "isoform_ac": "A0A8V0Z1C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C7/entry", "sequence": { "sequence": "MNRVPNDAENAHSSSVESCPSLRDVHSINPTHLMARIESYDVREKKGISDVRRTFCLFVTFDLLFITLLWIIELNVKGGIETTLKKEVLHYDYSSSYFDIFLLAVFRFKVLILAYAMCRLRHWWAIAFTTAVTSAFLLAKVIISQLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRRRDTITNSLADSFLRWKRKNKEIMVENLLHA", "length": 216, "header": "tr|A0A8V0Z1C7-1|A0A1L1RKF5_CHICK Computationally mapped isoform of STARD3 N-terminal like OS=Gallus gallus OX=9031 GN=STARD3NL PE=3 SV=1 CANONICAL=A0A1L1RKF5-1" }, "locus": { "chromosome": "2", "start_pos": 45967168, "end_pos": 45959273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038796.1", "url": "https://www.ensembl.org/id/ENSGALT00010038796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022434.1", "url": "https://www.ensembl.org/id/ENSGALP00010022434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420730", "resource": "KEGG Pathway" }, { "id": "R-GGA-196108", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "resource": "Reactome", "description": "Pregnenolone biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT75-1", "protein_name": "STARD3 N-terminal like", "gene_name": "Stard3nl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHLPEDMENTLTGSQSSHASLRDIHSINPGQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVAHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGSEEEAEEKQDSEKPLLEL", "length": 235 }, "evidence": [ { "id": "A0A1L1RKF5", "url": "https://omabrowser.org/oma/group/A0A1L1RKF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2QCA3-1", "protein_name": "STARD3 N-terminal-like protein", "gene_name": "Stard3nl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNHQPEDMENTLTGSQSSHASLRDIHPINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKREVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAVLIPAGLSDGQFYSPPESEAGSEEEAEEKQDSEKPLLEL", "length": 235 }, "evidence": [ { "id": "A0A1L1RKF5", "url": "https://omabrowser.org/oma/group/A0A1L1RKF5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95772-1", "protein_name": "STARD3 N-terminal-like protein", "gene_name": "STARD3NL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL", "length": 234 }, "evidence": [ { "id": "A0A1L1RKF5", "url": "https://omabrowser.org/oma/group/A0A1L1RKF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCI3-1", "protein_name": "STARD3 N-terminal-like protein", "gene_name": "Stard3nl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNHLPEHMENTLTGSQSSHASLRDIHSINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGSEEEAEEKQESEKPLLEL", "length": 235 }, "evidence": [ { "id": "A0A1L1RKF5", "url": "https://omabrowser.org/oma/group/A0A1L1RKF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" }, { "name": "endoplasmic reticulum-endosome membrane contact site", "id": "GO:0140284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140284", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cholesterol transport", "id": "GO:0030301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030301", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" }, { "name": "vesicle tethering to endoplasmic reticulum", "id": "GO:0099044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099044", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKF5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PVD0-1", "uniprot_ac": "A0A1D5PVD0", "uniprot_id": "A0A1D5PVD0_CHICK", "mass": { "chemical_mass": 36770.0, "monoisotopic_mass": 36770.0 }, "refseq": { "ac": "XP_015141478", "name": "spondin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141478" }, "gene_names": [ { "name": "SPON2", "type": "recommended", "evidence": [ { "id": "A0A1D5PVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ] }, { "name": "SPON2", "type": "synonym", "evidence": [ { "id": "XP_015141478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141478" } ] } ], "protein_names": [ { "name": "Spondin-2", "type": "recommended", "evidence": [ { "id": "A0A1D5PVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0/entry#names_and_taxonomy" } ] }, { "name": "Mindin", "type": "synonym", "evidence": [ { "id": "A0A1D5PVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0/entry#names_and_taxonomy" } ] }, { "name": "spondin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015141478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141478" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141478" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPON2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0", "locus": { "chromosome": "4", "start_pos": 84409204, "end_pos": 84385433, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017676", "url": "https://www.ensembl.org/id/ENSGALG00010017676" } ] } } ], "crossref": [ { "id": "A0A1D5PVD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038433", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038433", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422905", "url": "https://www.ncbi.nlm.nih.gov/gene/422905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVD0", "url": "https://www.orthodb.org/?gene=A0A1D5PVD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENLMFVYCSCKVIWTLLVTILGYASSLPLGDDSICTAEELAKYSIIFTGKWSQTAFPKQYPLYRPPAQWSSMLGVTHSSDYSMWKKNEYASNGVRDFAEKGEAWVLMKEIEEAGEKIQSVHGIFSAPAISSGTGQTSTELQVHSRHPLVSFVVRIVPSPDWFVGIDSLNLCEGDHWMEEISVDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITCSSPSHPANSFYYPKLKILPPIAQVTMVKLKKNQLGFPIPHLNQPAKSNEILDTFSETPLDCEVSQWSSWGLCRGPCRKMGTKIRTRFVVLHPANDGTPCPSLEEETECEPDNCV", "length": 330, "header": "tr|A0A1D5PVD0-1|A0A1D5PVD0_CHICK Isoform 1 of Spondin-2 OS=Gallus gallus OX=9031 GN=SPON2 PE=4 SV=1 CANONICAL=A0A1D5PVD0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0/entry", "sequence": { "sequence": "MENLMFVYCSCKVIWTLLVTILGYASSLPLGDDSICTAEELAKYSIIFTGKWSQTAFPKQYPLYRPPAQWSSMLGVTHSSDYSMWKKNEYASNGVRDFAEKGEAWVLMKEIEEAGEKIQSVHGIFSAPAISSGTGQTSTELQVHSRHPLVSFVVRIVPSPDWFVGIDSLNLCEGDHWMEEISVDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITCSSPSHPANSFYYPKLKILPPIAQVTMVKLKKNQLGFPIPHLNQPAKSNEILDTFSETPLDCEVSQWSSWGLCRGPCRKMGTKIRTRFVVLHPANDGTPCPSLEEETECEPDNCV", "length": 330, "header": "tr|A0A1D5PVD0-1|A0A1D5PVD0_CHICK Isoform 1 of Spondin-2 OS=Gallus gallus OX=9031 GN=SPON2 PE=4 SV=1 CANONICAL=A0A1D5PVD0-1" }, "locus": { "chromosome": "4", "start_pos": 84408341, "end_pos": 84403633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042738.1", "url": "https://www.ensembl.org/id/ENSGALT00010042738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025228.1", "url": "https://www.ensembl.org/id/ENSGALP00010025228.1" } ] } }, { "isoform_ac": "A0A8V0YVX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX0/entry", "sequence": { "sequence": "MFSANLESLKITIIVGPKGPSSGINTNTPTVFSCRPTQLPAKAGALPLPVLQRKYLGMENLMFVYCSCKVIWTLLVTILGYASSLPLGDDSICTAEELAKYSIIFTGKWSQTAFPKQYPLYRPPAQWSSMLGVTHSSDYSMWKKNEYASNGVRDFAEKGEAWVLMKEIEEAGEKIQSVHGIFSAPAISSGTGQTSTELQVHSRHPLVSFVVRIVPSPDWFVGIDSLNLCEGDHWMEEISVDLYPYDAGTDSGFTFSSPNFATIPQDTVTEGSLFISQITCSSPSHPANSFYYPKLKILPPIAQVTMVKLKKNQLGFPIPHLNQPAKSNEILDTFSETPLDCEVSQWSSWGLCRGPCRKMGTKIRTRFVVLHPANDGTPCPSLEEETECEPDNCV", "length": 394, "header": "tr|A0A8V0YVX0-1|A0A1D5PVD0_CHICK Computationally mapped isoform of Spondin-2 OS=Gallus gallus OX=9031 GN=SPON2 PE=4 SV=1 CANONICAL=A0A1D5PVD0-1" }, "locus": { "chromosome": "4", "start_pos": 84408341, "end_pos": 84402664, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042735.1", "url": "https://www.ensembl.org/id/ENSGALT00010042735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025225.1", "url": "https://www.ensembl.org/id/ENSGALP00010025225.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" }, { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" }, { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PVD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVD0" }, { "id": "PS51020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spondin", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 222, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PD03-1", "uniprot_ac": "A0A1D5PD03", "uniprot_id": "A0A1D5PD03_CHICK", "mass": { "chemical_mass": 94470.0, "monoisotopic_mass": 94470.0 }, "refseq": { "ac": "NP_001006484", "name": "tetratricopeptide repeat protein 7B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484" }, "gene_names": [ { "name": "TTC7B", "type": "recommended", "evidence": [ { "id": "A0A1D5PD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ] }, { "name": "TTC7B", "type": "synonym", "evidence": [ { "id": "NP_001006484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 7B", "type": "recommended", "evidence": [ { "id": "A0A1D5PD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 7 like-1", "type": "synonym", "evidence": [ { "id": "NP_001006484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484" } ] }, { "name": "tetratricopeptide repeat protein 7B", "type": "synonym", "evidence": [ { "id": "NP_001006484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720692.1, SRR12888496.228857.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Mar 18, 2015 this sequence version replaced NP_001006484.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484" } ] }, { "annotation": "Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03#function" }, { "database": "UniProtKB", "id": "ARBA00054379", "url": "https://www.uniprot.org/uniprotkb/ARBA00054379#function" }, { "database": "UniProtKB", "id": "A0A8V0Z2F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F9#function" }, { "database": "UniProtKB", "id": "A0A8V0Z2W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W6#function" }, { "database": "UniProtKB", "id": "A0A8V0Z440", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z440#function" }, { "database": "UniProtKB", "id": "A0A8V0YW02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW02#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC7B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03", "locus": { "chromosome": "5", "start_pos": 43502778, "end_pos": 43624885, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017687", "url": "https://www.ensembl.org/id/ENSGALG00010017687" } ] } } ], "crossref": [ { "id": "A0A1D5PD03", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PD03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010680", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010680", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423407", "url": "https://www.ncbi.nlm.nih.gov/gene/423407", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423407", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423407", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PD03", "url": "https://www.orthodb.org/?gene=A0A1D5PD03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW02", "url": "https://www.orthodb.org/?gene=A0A8V0YW02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2F9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2W6", "url": "https://www.orthodb.org/?gene=A0A8V0Z2W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z431", "url": "https://www.orthodb.org/?gene=A0A8V0Z431", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z435", "url": "https://www.orthodb.org/?gene=A0A8V0Z435", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z440", "url": "https://www.orthodb.org/?gene=A0A8V0Z440", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23083:SF365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23083:SF365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PD03-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z431", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z431", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z431-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z431-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z435", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z435", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z435-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z435-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z440", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z440", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z440-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z440-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 843, "header": "tr|A0A1D5PD03-1|A0A1D5PD03_CHICK Isoform 1 of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PD03-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 843, "header": "tr|A0A1D5PD03-1|A0A1D5PD03_CHICK Isoform 1 of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042782.1", "url": "https://www.ensembl.org/id/ENSGALT00010042782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025272.1", "url": "https://www.ensembl.org/id/ENSGALP00010025272.1" } ] } }, { "isoform_ac": "A0A8V0YW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW02/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGKSSDAYFHGFYSLFSVCSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 860, "header": "tr|A0A8V0YW02-1|A0A1D5PD03_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042770.1", "url": "https://www.ensembl.org/id/ENSGALT00010042770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025260.1", "url": "https://www.ensembl.org/id/ENSGALP00010025260.1" } ] } }, { "isoform_ac": "A0A8V0Z2F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F9/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGINVHEDQQNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 851, "header": "tr|A0A8V0Z2F9-1|A0A1D5PD03_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042772.1", "url": "https://www.ensembl.org/id/ENSGALT00010042772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025262.1", "url": "https://www.ensembl.org/id/ENSGALP00010025262.1" } ] } }, { "isoform_ac": "A0A8V0Z2W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W6/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETASDTSSSSLSRTESPLQVFVSSHLPHPKSDTFVWPHAASPCCDQVPEPCSPSHWKSSDAYFHGFYSLFSVCSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 913, "header": "tr|A0A8V0Z2W6-1|A0A8V0Z2W6_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042769.1", "url": "https://www.ensembl.org/id/ENSGALT00010042769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025259.1", "url": "https://www.ensembl.org/id/ENSGALP00010025259.1" } ] } }, { "isoform_ac": "A0A8V0Z2Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y3/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 796, "header": "tr|A0A8V0Z2Y3-1|A0A8V0Z2Y3_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042784.1", "url": "https://www.ensembl.org/id/ENSGALT00010042784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025274.1", "url": "https://www.ensembl.org/id/ENSGALP00010025274.1" } ] } }, { "isoform_ac": "A0A8V0Z431-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z431/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAEINERKKQTSKDQSRDEGQLLSVFREGSFL", "length": 732, "header": "tr|A0A8V0Z431-1|A0A8V0Z431_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43534496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042768.1", "url": "https://www.ensembl.org/id/ENSGALT00010042768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025258.1", "url": "https://www.ensembl.org/id/ENSGALP00010025258.1" } ] } }, { "isoform_ac": "A0A8V0Z435-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z435/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETGSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLVHLKISSCILLCPKDNILSFHFSFRSTDTSPAWAL", "length": 805, "header": "tr|A0A8V0Z435-1|A0A8V0Z435_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505223, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042773.1", "url": "https://www.ensembl.org/id/ENSGALT00010042773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025263.1", "url": "https://www.ensembl.org/id/ENSGALP00010025263.1" } ] } }, { "isoform_ac": "A0A8V0Z440-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z440/entry", "sequence": { "sequence": "MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQFLKENALKQSSSPRGPRPKLTEVRKHLTAALDRGNLKPEFLQEANLLMAKLNYVEGDYKEALNTYARVGVDDLQLAAVPPYRLRMIAEAYSTKGLCLEKLPISSSASNLHVDREQEIVTCYEKAGDIALLYLQEIERVINTNIQNRSPKPGPTTHEQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPHQSPLDDPLRKGSNTKNYTLSRRPRVYTGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKNDRIISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAERFAKTVVDLGDKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHLAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFTKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRAIADRRQLNTITLPDFSDPETASDTSSSSLSRTESPLQVFVSSHLPHPKSDTFVWPHAASPCCDQVPEPCSPSHCSIHATSIAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHYVLYMRGQVAELRGNIDEAKRWYEEALSISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDDAATECFLTALELEASSPVVPFTIIPRVL", "length": 896, "header": "tr|A0A8V0Z440-1|A0A8V0Z440_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 7B OS=Gallus gallus OX=9031 GN=TTC7B PE=4 SV=1 CANONICAL=A0A1D5PD03-1" }, "locus": { "chromosome": "5", "start_pos": 43624727, "end_pos": 43505033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042778.1", "url": "https://www.ensembl.org/id/ENSGALT00010042778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025268.1", "url": "https://www.ensembl.org/id/ENSGALP00010025268.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423407", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423407", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD03" }, { "id": "PF19440", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19440" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 7 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 386, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 794, "end_pos": 796 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PAY3-1", "uniprot_ac": "A0A1D5PAY3", "uniprot_id": "A0A1D5PAY3_CHICK", "mass": { "chemical_mass": 192763.0, "monoisotopic_mass": 192763.0 }, "refseq": { "ac": "XP_040511938", "name": "transient receptor potential cation channel subfamily M member 3 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511938" }, "gene_names": [ { "name": "TRPM3", "type": "recommended", "evidence": [ { "id": "A0A1D5PAY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ] }, { "name": "TRPM3", "type": "synonym", "evidence": [ { "id": "XP_040511938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511938" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily M member 3", "type": "recommended", "evidence": [ { "id": "A0A1D5PAY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3/entry#names_and_taxonomy" } ] }, { "name": "transient receptor potential cation channel subfamily M member 3 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_040511938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511938" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511938" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3", "locus": { "chromosome": "Z", "start_pos": 35692395, "end_pos": 36116813, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016618", "url": "https://www.ensembl.org/id/ENSGALG00010016618" } ] } } ], "crossref": [ { "id": "ENSGALG00000015126", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427249", "url": "https://www.ncbi.nlm.nih.gov/gene/427249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PAY3", "url": "https://www.orthodb.org/?gene=A0A1D5PAY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWS2", "url": "https://www.orthodb.org/?gene=A0A8V0YWS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX62", "url": "https://www.orthodb.org/?gene=A0A8V0YX62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYN3", "url": "https://www.orthodb.org/?gene=A0A8V0YYN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3S0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3T0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3T6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "28699", "url": "https://www.rhea-db.org/rhea/28699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29351", "url": "https://www.rhea-db.org/rhea/29351", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29827", "url": "https://www.rhea-db.org/rhea/29827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1689, "header": "tr|A0A1D5PAY3-1|A0A1D5PAY3_CHICK Isoform 1 of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3/entry", "sequence": { "sequence": "MNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1689, "header": "tr|A0A1D5PAY3-1|A0A1D5PAY3_CHICK Isoform 1 of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 35951446, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040099.1", "url": "https://www.ensembl.org/id/ENSGALT00010040099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023243.1", "url": "https://www.ensembl.org/id/ENSGALP00010023243.1" } ] } }, { "isoform_ac": "A0A8V0YWS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWS2/entry", "sequence": { "sequence": "MKNKQVNLAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTANSRSCPQEPVCRQAEGPAYRTQYAGKLKEQPTRPTYRTRLQAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1697, "header": "tr|A0A8V0YWS2-1|A0A1D5PAY3_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 36116531, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040081.1", "url": "https://www.ensembl.org/id/ENSGALT00010040081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023230.1", "url": "https://www.ensembl.org/id/ENSGALP00010023230.1" } ] } }, { "isoform_ac": "A0A8V0YX62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX62/entry", "sequence": { "sequence": "MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTANSRSCPQEPVCRQAEGPAYRTQYAGKLKEQPTRPTYRTRLQAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1595, "header": "tr|A0A8V0YX62-1|A0A1D5PAY3_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 35820629, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040078.1", "url": "https://www.ensembl.org/id/ENSGALT00010040078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023227.1", "url": "https://www.ensembl.org/id/ENSGALP00010023227.1" } ] } }, { "isoform_ac": "A0A8V0YYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN3/entry", "sequence": { "sequence": "MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTREVFQPFDHLHGPPLDPLQQLHILPVLGPQAWTQCSIWALTRAEQKGTISSLILLNLNPLLMQPRL", "length": 237, "header": "tr|A0A8V0YYN3-1|A0A1D5PAY3_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 35820629, "end_pos": 35794892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040067.1", "url": "https://www.ensembl.org/id/ENSGALT00010040067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023216.1", "url": "https://www.ensembl.org/id/ENSGALP00010023216.1" } ] } }, { "isoform_ac": "A0A8V0Z3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S0/entry", "sequence": { "sequence": "MAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDRKQVYDSHTPKSAPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1660, "header": "tr|A0A8V0Z3S0-1|A0A8V0Z3S0_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 36115510, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040075.1", "url": "https://www.ensembl.org/id/ENSGALT00010040075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023224.1", "url": "https://www.ensembl.org/id/ENSGALP00010023224.1" } ] } }, { "isoform_ac": "A0A8V0Z3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T0/entry", "sequence": { "sequence": "MGQKRRSPGAAERGCAAEGTTGGSGRGRLAESWRRLSSRRGSAKRSGTSAPAPPAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTANSRSCPQEPVCRQAEGPAYRTQYAGKLKEQPTRPTYRTRLQAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1743, "header": "tr|A0A8V0Z3T0-1|A0A8V0Z3T0_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 36080785, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040086.1", "url": "https://www.ensembl.org/id/ENSGALT00010040086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023234.1", "url": "https://www.ensembl.org/id/ENSGALP00010023234.1" } ] } }, { "isoform_ac": "A0A8V0Z3T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T6/entry", "sequence": { "sequence": "MNQTDAPRPLNWTIRKLCHAAFLPSVRLLKAQKSWIERAFYKRECVHIVPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNESRLTRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVICDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDVPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQANEIHLQEKEPEEPEKPVKEKEEEDMELTANSRSCPQEPVCRQAEGPAYRTQYAGKLKEQPTRPTYRTRLQAMLGRGNGESSRKKEEEEVQSRHRLIPVGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMDRWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMVLRLQDLPLRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITEDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMAMRLEEVNEREHCMKASLQTVDIRLAQLEDMIGRMVTALEKLTGIERGEATKIRSRTSSDCTDAAYIVRQSSFNSQEGNTYKLQESIDPTGEESMSPTSPTITPRMRSHSFYATNMKDKCGLEKFESIFKERSPSLHRASSSHSLAKEGKVPLAPTSTLSIAPDSRRPSSCIDIYVSAMDEMHSDTEPLDSSINILGTGEVALQAHIASSILANSAYISSTPGEKISGRSLDYEETSGIETRAFSSDYSQITECQIPWDSDPPLYHTLERSKSSRYLATTPFILEETPIVKSHSFMFSPSRSYFSSLGVPVKTAEYTSITDCIDTRCVSAPQTIAERASFPGSLGVKVEDLGCCHPEREAELSHPSSDHEDTEAKEKKGIPLSPQDSNAARTLTNSIPLPKIERANSYSAEESNMLYAQHTRKSYSISDKLDRQRNATSLRNPFQRSKSSRPESRGDNLSMRRLSRTGAFRSFESKHS", "length": 1719, "header": "tr|A0A8V0Z3T6-1|A0A8V0Z3T6_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 3 OS=Gallus gallus OX=9031 GN=TRPM3 PE=3 SV=1 CANONICAL=A0A1D5PAY3-1" }, "locus": { "chromosome": "Z", "start_pos": 35951446, "end_pos": 35693399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040095.1", "url": "https://www.ensembl.org/id/ENSGALT00010040095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023239.1", "url": "https://www.ensembl.org/id/ENSGALP00010023239.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1432, "start_aa": "Thr", "end_pos": 1432, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1432", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAY3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1194, "end_pos": 1196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1647, "end_pos": 1649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1669, "end_pos": 1671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417653", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417653" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2", "locus": { "chromosome": "21", "start_pos": 6059955, "end_pos": 6061825, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016905", "url": "https://www.ensembl.org/id/ENSGALG00010016905" } ] } } ], "crossref": [ { "id": "A0A1D5PGB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PGB2", "database": 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"MLNQESMGLEMGHHKTSSVCLGLMMSSTSTHLHPYHLTASTSTKMGQSFRDQLHLALILLLLRLESAVTSDPPHSCYGAPGLPGMPGVPGRDGRDGLKGAKGEPGIPAIPTMQGPKGMKGDPGSPGLKGKVGPFGPAGPPGDPGVMGAAGQKGLPGSLKRMHQSAFSVTRQTREHPMKNTPVVFNNIITNTNNDYSTTTGKFTSKVPGLYYFVYHSSMERNLCVLLYQDKVKKASFCDHKTNNIQVTSGGVLLHLEAGNQVWLEVNDYNGMVGTGESDSIFSGFLLFPD", "length": 289, "header": "tr|A0A8V0YYN1-1|A0A1D5PGB2_CHICK Computationally mapped isoform of Complement C1q C chain OS=Gallus gallus OX=9031 GN=C1QC PE=4 SV=1 CANONICAL=A0A1D5PGB2-1" }, "locus": { "chromosome": "21", "start_pos": 6061215, "end_pos": 6060027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040794.1", "url": "https://www.ensembl.org/id/ENSGALT00010040794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023758.1", "url": "https://www.ensembl.org/id/ENSGALP00010023758.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419503", "resource": "KEGG Pathway" }, { "id": "R-GGA-173623", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-173623", "resource": "Reactome", "description": "Classical antibody-mediated complement activation" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZSJ7-1", "protein_name": "Complement C1q C chain", "gene_name": "C1QC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDMGSSSWPLLVLNLLLLLLALPLEGQDNLRCHGIPGIPGLPGAPGKDGHDGLPGPKGEPGIPAIPGTRGPKGEKGDPGKPGLPGKNGPMGTPGIPGTPGVMGPRGEPGEEGRYKQKHQSVFSVTRQTAQYPAANSLVKFNNVITNPQGDYDINTGKFTCKVPGLYYFVYYTSHTANLCMLLYRNGFKVITFCDHMSNSKQVSSGGVLLRLQEGEQVWLGVNDYNGLVGMEGSDSIFSGFLLFPN", "length": 245 }, "evidence": [ { "id": "A0A1D5PGB2", "url": "https://omabrowser.org/oma/group/A0A1D5PGB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LGM6-1", "protein_name": "Complement C1q subcomponent subunit C", "gene_name": "C1qc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDVGPSCQPQRGLYLTLLLLALTLRSQANTNCYGIPGMPGLPGAPGKDGHDGLPGPKGERGIPAIPGTRGPKGQKGEPGMPGYRGKNGPMGPSGLPGDPGPRGPPGEPGEEGRYKQKHQSVFTVTRQTAQYPAANGLVKFNSVVTNPQGDYDTSTGKFTCKVPGLYYFVYHASQTANLCVQLLHNSAKVTTFCDHMSNSKQVSSGGVLLRLQKGDEVWLAVNDYNGMVGTEGSDSVFSGFLLFPD", "length": 245 }, "evidence": [ { "id": "A0A1D5PGB2", "url": "https://omabrowser.org/oma/group/A0A1D5PGB2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P02747-1", "protein_name": "Complement C1q subcomponent subunit C", "gene_name": "C1QC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCVLLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLFPD", "length": 245 }, "evidence": [ { "id": "A0A1D5PGB2", "url": "https://omabrowser.org/oma/group/A0A1D5PGB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02105-1", "protein_name": "Complement C1q subcomponent subunit C", "gene_name": "C1qc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVGPSCQPPCGLCLLLLFLLALPLRSQASAGCYGIPGMPGMPGAPGKDGHDGLQGPKGEPGIPAVPGTRGPKGQKGEPGMPGHRGKNGPRGTSGLPGDPGPRGPPGEPGVEGRYKQKHQSVFTVTRQTTQYPEANALVRFNSVVTNPQGHYNPSTGKFTCEVPGLYYFVYYTSHTANLCVHLNLNLARVASFCDHMFNSKQVSSGGVLLRLQRGDEVWLSVNDYNGMVGIEGSNSVFSGFLLFPD", "length": 246 }, "evidence": [ { "id": "A0A1D5PGB2", "url": "https://omabrowser.org/oma/group/A0A1D5PGB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "extrinsic component of presynaptic membrane", "id": "GO:0098888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "extrinsic component of postsynaptic membrane", "id": "GO:0098890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098890", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "complement component C1 complex", "id": "GO:0005602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005602", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "complement component C1q complex", "id": "GO:0062167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062167", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "symbiont cell surface", "id": "GO:0106139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106139", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "IgM binding", "id": "GO:0001791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001791", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "IgG binding", "id": "GO:0019864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019864", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of granulocyte differentiation", "id": "GO:0030853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030853", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "negative regulation of macrophage differentiation", "id": "GO:0045650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045650", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "synapse pruning", "id": "GO:0098883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098883", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGB2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PYR7-1", "uniprot_ac": "A0A1D5PYR7", "uniprot_id": "A0A1D5PYR7_CHICK", "mass": { "chemical_mass": 64382.0, "monoisotopic_mass": 64382.0 }, "refseq": { "ac": "XP_015132273", "name": "kelch-like protein 28", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132273" }, "gene_names": [ { "name": "KLHL28", "type": "recommended", "evidence": [ { "id": "A0A1D5PYR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ] }, { "name": "KLHL28", "type": "synonym", "evidence": [ { "id": "XP_015132273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132273" } ] } ], "protein_names": [ { "name": "Kelch like family member 28", "type": "synonym", "evidence": [ { "id": "A0A1D5PYR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 28", "type": "synonym", "evidence": [ { "id": "XP_015132273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132273" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132273" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL28", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7", "locus": { "chromosome": "5", "start_pos": 58628250, "end_pos": 58612991, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018394", "url": "https://www.ensembl.org/id/ENSGALG00010018394" } ] } } ], "crossref": [ { "id": "A0A1D5PYR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PYR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012489", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18467", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18467", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423596", "url": "https://www.ncbi.nlm.nih.gov/gene/423596", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423596", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423596", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAGMMYC", "url": "https://omabrowser.org/oma/group/TAGMMYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYR7", "url": "https://www.orthodb.org/?gene=A0A1D5PYR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZK5", "url": "https://www.orthodb.org/?gene=A0A8V0YZK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQSSPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCVDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVVKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAANKYICQNFEDVCQTEEFFELTHSELDEIVSNDCLNVVTEETVFYALESWIKYDVQERQKYLAQLLHCVRLPLLSVKFLTRLYEANHLIRDDHTCKHLLNEALKYHFMPEHRLSHQTMLMTRPRCAPKVLCAVGGKAGLFACLESVEMYFPQNDSWIGLAPLSIPRYEFGICVLDQKIYVVGGIATHVCQGISYRKHENSVECWDPDTNTWTSLERMFESRSTLGVVVLAGELYALGGYDGQSYLRTVEKYIPKVKEWQLVAPMNKTRSCFAAAVLDGMIYAIGGYGPAHMNSMERYDPSKNSWETVASMADKRINFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMMYCRCNFGLTAL", "length": 571, "header": "tr|A0A1D5PYR7-1|A0A1D5PYR7_CHICK Isoform 1 of Kelch like family member 28 OS=Gallus gallus OX=9031 GN=KLHL28 PE=4 SV=2 CANONICAL=A0A1D5PYR7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PYR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7/entry", "sequence": { "sequence": "MDQSSPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCVDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVVKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAANKYICQNFEDVCQTEEFFELTHSELDEIVSNDCLNVVTEETVFYALESWIKYDVQERQKYLAQLLHCVRLPLLSVKFLTRLYEANHLIRDDHTCKHLLNEALKYHFMPEHRLSHQTMLMTRPRCAPKVLCAVGGKAGLFACLESVEMYFPQNDSWIGLAPLSIPRYEFGICVLDQKIYVVGGIATHVCQGISYRKHENSVECWDPDTNTWTSLERMFESRSTLGVVVLAGELYALGGYDGQSYLRTVEKYIPKVKEWQLVAPMNKTRSCFAAAVLDGMIYAIGGYGPAHMNSMERYDPSKNSWETVASMADKRINFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMMYCRCNFGLTAL", "length": 571, "header": "tr|A0A1D5PYR7-1|A0A1D5PYR7_CHICK Isoform 1 of Kelch like family member 28 OS=Gallus gallus OX=9031 GN=KLHL28 PE=4 SV=2 CANONICAL=A0A1D5PYR7-1" }, "locus": { "chromosome": "5", "start_pos": 58624556, "end_pos": 58617250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044420.1", "url": "https://www.ensembl.org/id/ENSGALT00010044420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026433.1", "url": "https://www.ensembl.org/id/ENSGALP00010026433.1" } ] } }, { "isoform_ac": "A0A8V0YZK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK5/entry", "sequence": { "sequence": "MHHSVPVVLQLHRVHRLEEKAALPGPHGRRQQGERLQGGVPHSALAVQQRRGEAEGQPAQVQLPAGMDQSSPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCVDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVVKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAANKYICQNFEDVCQTEEFFELTHSELDEIVSNDCLNVVTEETVFYALESWIKYDVQERQKYLAQLLHCVRLPLLSVKFLTRLYEANHLIRDDHTCKHLLNEALKYHFMPEHRLSHQTMLMTRPRCAPKVLCAVGGKAGLFACLESVEMYFPQNDSWIGLAPLSIPRYEFGICVLDQKIYVVGGIATHVCQGISYRKHENSVECWDPDTNTWTSLERMFESRSTLGVVVLAGELYALGGYDGQSYLRTVEKYIPKVKEWQLVAPMNKTRSCFAAAVLDGMIYAIGGYGPAHMNSMERYDPSKNSWETVASMADKRINFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMMYCRCNFGLTAL", "length": 637, "header": "tr|A0A8V0YZK5-1|A0A1D5PYR7_CHICK Computationally mapped isoform of Kelch like family member 28 OS=Gallus gallus OX=9031 GN=KLHL28 PE=4 SV=1 CANONICAL=A0A1D5PYR7-1" }, "locus": { "chromosome": "5", "start_pos": 58624556, "end_pos": 58613050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044423.1", "url": "https://www.ensembl.org/id/ENSGALT00010044423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026436.1", "url": "https://www.ensembl.org/id/ENSGALP00010026436.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423596", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423596", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MV16-1", "protein_name": "Kelch-like protein 28 isoform X2", "gene_name": "Klhl28", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDHTSPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIVLRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCIDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAATKYICQNFESVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHRLSHQTVLITRPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVYVIGGIETSVRPGVTVRKHENSVECWNPDTNTWTSLERMNESRSTLGVVVLAGELYALGGYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMIYAIGGYGPAHMNSVERYDPSKDSWEMVASMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVVDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGLTAL", "length": 571 }, "evidence": [ { "id": "A0A1D5PYR7", "url": "https://omabrowser.org/oma/group/A0A1D5PYR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AC05-1", "protein_name": "Kelch-like family member 28", "gene_name": "Klhl28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPSFSQMDHTAPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCIDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCTFLESQLDPGNCIGISRFAETYGCHDLYLAATKFICQNFESVCQTEEFFELTHGDLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHRLSHQTVLMTRPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVYVIGGIETSVRPGVTVRKHENSVECWNPDTNTWTSLERMNESRSTLGVVVLAGEVYALGGYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMIYAIGGYGPAHMNSVERYDPSKDSWETVASMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGLTAL", "length": 578 }, "evidence": [ { "id": "A0A1D5PYR7", "url": "https://omabrowser.org/oma/group/A0A1D5PYR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CR40-1", "protein_name": "Kelch-like protein 28", "gene_name": "Klhl28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDHTAPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKENSEVEFQCIDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCHDLYLAATKFICQNFESVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHRLSHQTVLMTRPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVFVIGGIETSVRPGMTVRKHENSVECWNPDTNTWTSLERMNESRSTLGVAVLAGEVFALGGYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMLYAIGGYGPAHMNSVERYDPSKDSWEMVAPMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGLTAL", "length": 571 }, "evidence": [ { "id": "A0A1D5PYR7", "url": "https://omabrowser.org/oma/group/A0A1D5PYR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXS3-1", "protein_name": "Kelch-like protein 28", "gene_name": "KLHL28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDHTSPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASVSPYFKAMFTGNLSEKENSEVEFQCIDETALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCRDLYLAATKYICQNFEAVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHRLSHQTVLMTRPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVYVIGGIATNVRPGVTIRKHENSVECWNPDTNTWTSLERMNESRSTLGVVVLAGELYALGGYDGQSYLQSVEKYIPKIRKWQPVAPMTTTRSCFAAAVLDGMIYAIGGYGPAHMNSVERYDPSKDSWEMVASMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGLTAL", "length": 571 }, "evidence": [ { "id": "A0A1D5PYR7", "url": "https://omabrowser.org/oma/group/A0A1D5PYR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYR7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PKH6-1", "uniprot_ac": "A0A1D5PKH6", "uniprot_id": "A0A1D5PKH6_CHICK", "mass": { "chemical_mass": 24649.0, "monoisotopic_mass": 24649.0 }, "refseq": { "ac": "NP_001258073", "name": "N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258073" }, "gene_names": [ { "name": "NAT8B", "type": "recommended", "evidence": [ { "id": "A0A1D5PKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6" } ] }, { "name": "NAT8B", "type": "synonym", "evidence": [ { "id": "NP_001258073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258073" } ] } ], "protein_names": [ { "name": "N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)", "type": "synonym", "evidence": [ { "id": "NP_001258073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258073" } ] }, { "name": "N-acetyltransferase 8B (putative,/pseudo", "type": "synonym", "evidence": [ { "id": "A0A1D5PKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX930613.1, BU123557.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000081.1. On Sep 5, 2012 this sequence version replaced XP_001236424.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001258073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258073" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKH6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAT8B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6", "locus": { "chromosome": "4", "start_pos": 90501780, "end_pos": 90496765, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017502", "url": "https://www.ensembl.org/id/ENSGALG00010017502" } ] } } ], "crossref": [ { "id": "ENSGALG00000033857", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776932", "url": "https://www.ncbi.nlm.nih.gov/gene/776932", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776932", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776932", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKIPDTH", "url": "https://omabrowser.org/oma/group/YKIPDTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKH6", "url": "https://www.orthodb.org/?gene=A0A1D5PKH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1K2", "url": "https://www.orthodb.org/?gene=A0A8V0Z1K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13947:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13947:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001258073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKH6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPYRIRLYRDEDYDAVRSLFARGILEHAPAIYRHMLRSTRVQLGLLALFTAVRAVAGSWLLALAAVALVLAATWPVMRSFSTSYVQEALITDLCDIDSCYMRAPDSCFWVVEAGGAVVGMVAVAPPQDPAQRGEALELKRMSVSKDHRGQGISKALCGEVLRFAQARGYRAVMLYTSIVQVVAQRLYESQGFRKVGAISPSLLASLVSFQIFQYRCELPGRP", "length": 223, "header": "tr|A0A1D5PKH6-1|A0A1D5PKH6_CHICK Isoform 1 of N-acetyltransferase 8B (putative,/pseudo OS=Gallus gallus OX=9031 GN=NAT8B PE=4 SV=1 CANONICAL=A0A1D5PKH6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6/entry", "sequence": { "sequence": "MAPYRIRLYRDEDYDAVRSLFARGILEHAPAIYRHMLRSTRVQLGLLALFTAVRAVAGSWLLALAAVALVLAATWPVMRSFSTSYVQEALITDLCDIDSCYMRAPDSCFWVVEAGGAVVGMVAVAPPQDPAQRGEALELKRMSVSKDHRGQGISKALCGEVLRFAQARGYRAVMLYTSIVQVVAQRLYESQGFRKVGAISPSLLASLVSFQIFQYRCELPGRP", "length": 223, "header": "tr|A0A1D5PKH6-1|A0A1D5PKH6_CHICK Isoform 1 of N-acetyltransferase 8B (putative,/pseudo OS=Gallus gallus OX=9031 GN=NAT8B PE=4 SV=1 CANONICAL=A0A1D5PKH6-1" }, "locus": { "chromosome": "4", "start_pos": 90501293, "end_pos": 90500625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042292.1", "url": "https://www.ensembl.org/id/ENSGALT00010042292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024787.1", "url": "https://www.ensembl.org/id/ENSGALP00010024787.1" } ] } }, { "isoform_ac": "A0A8V0Z1K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1K2/entry", "sequence": { "sequence": "MGTRGPPRCMMPGWGRAPLPTSGPAAPQARGAQPPWGAPTPPRPPAEWGPTEGPLSVSPRRAGVRFAPAPLNAAIIKEHRSAARGPSLHRGVTVRASPAAPWALTAFARRFKGAERCYAPRPRRAALPQRWAKPPGGGADVGWGFAAPRGLNCPRRPSIARRASLGPGPRGGAAGSRLLAGLRDRRCPPAAARPCAPAPLPMAPYRIRLYRDEDYDAVRSLFARGILEHAPAIYRHMLRSTRVQLGLLALFTAVRAVAGSWLLALAAVALVLAATWPVMRSFSTSYVQEALITDLCDIDSCYMRAPDSCFWVVEAGGAVVGMVAVAPPQDPAQRGEALELKRMSVSKDHRGQGISKALCGEVLRFAQARGYRAVMLYTSIVQVVAQRLYESQGFRKVGAISPSLLASLVSFQIFQYRCELPGRP", "length": 424, "header": "tr|A0A8V0Z1K2-1|A0A1D5PKH6_CHICK Computationally mapped isoform of N-acetyltransferase 8B (putative,/pseudo OS=Gallus gallus OX=9031 GN=NAT8B PE=4 SV=1 CANONICAL=A0A1D5PKH6-1" }, "locus": { "chromosome": "4", "start_pos": 90501293, "end_pos": 90499061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042304.1", "url": "https://www.ensembl.org/id/ENSGALT00010042304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024796.1", "url": "https://www.ensembl.org/id/ENSGALP00010024796.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776932", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776932", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E0CYR6-1", "protein_name": "N-acetyltransferase family 8 member 7", "gene_name": "Nat8f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPYHIRKYQDSDHRSVVDLFRRGMEEHIPATFRHMLLLPRTLLLLLGVPLTLFLASGSWLLVLLSILTLFLSLWFLAKYTWEKHVMNCLHTDMADITRTYMSSHSSCFWVAESRGQTVGMVAARPVKDPLLQKKQLQLLHLSVSLQHRREGLGKAMVRTVLQFAQMQGFSEVVLSTSMLQYAALALYQGMGFQKTGETFYTYLSRLRKSPMINLKYSLTSPWEGDL", "length": 227 }, "evidence": [ { "id": "A0A1D5PKH6", "url": "https://omabrowser.org/oma/group/A0A1D5PKH6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKH6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKH6" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 220, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RP46-1", "uniprot_ac": "A0A1L1RP46", "uniprot_id": "A0A1L1RP46_CHICK", "mass": { "chemical_mass": 22708.0, "monoisotopic_mass": 22708.0 }, "refseq": { "ac": "NP_001257591", "name": "ras-related protein Rab-1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" }, "gene_names": [ { "name": "RAB1B", "type": "recommended", "evidence": [ { "id": "A0A1L1RP46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ] }, { "name": "RAB1A", "type": "synonym", "evidence": [ { "id": "NP_001257591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] }, { "name": "RAB1B", "type": "synonym", "evidence": [ { "id": "NP_001257591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] } ], "protein_names": [ { "name": "GTP binding protein Rab1a", "type": "synonym", "evidence": [ { "id": "NP_001257591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] }, { "name": "RAB1A, member RAS oncogene family", "type": "synonym", "evidence": [ { "id": "NP_001257591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] }, { "name": "RAB1B, member RAS onco family", "type": "synonym", "evidence": [ { "id": "A0A1L1RP46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-1A", "type": "synonym", "evidence": [ { "id": "NP_001257591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004128.1, HAEK01024030.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000061.1. On Jul 26, 2012 this sequence version replaced XP_419342.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene.The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001257591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB1B", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46", "locus": { "chromosome": "3", "start_pos": 10149678, "end_pos": 10172244, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017622", "url": "https://www.ensembl.org/id/ENSGALG00010017622" } ] } } ], "crossref": [ { "id": "A0A1L1RP46", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RP46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031582", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421273", "url": "https://www.ncbi.nlm.nih.gov/gene/421273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421273", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQMAKDF", "url": "https://omabrowser.org/oma/group/TQMAKDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PE33", "url": "https://www.orthodb.org/?gene=A0A1D5PE33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RP46", "url": "https://www.orthodb.org/?gene=A0A1L1RP46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9E9", "url": "https://www.orthodb.org/?gene=A0A8V0Z9E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9F3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001257591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PE33", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSSGGCC", "length": 205, "header": "tr|A0A1L1RP46-1|A0A1L1RP46_CHICK Isoform 1 of RAB1B, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB1B PE=1 SV=2 CANONICAL=A0A1L1RP46-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE33/entry", "sequence": { "sequence": "SVKVLLGLVLPTCCATCVQQAGWCERRRVSSDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSSGGCC", "length": 228, "header": "tr|A0A1D5PE33-1|A0A1L1RP46_CHICK Computationally mapped isoform of RAB1B, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB1B PE=1 SV=2 CANONICAL=A0A1L1RP46-1" }, "locus": { "chromosome": "3", "start_pos": 10160775, "end_pos": 10151559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042586.1", "url": "https://www.ensembl.org/id/ENSGALT00010042586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025076.1", "url": "https://www.ensembl.org/id/ENSGALP00010025076.1" } ] } }, { "isoform_ac": "A0A1L1RP46-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46/entry", "sequence": { "sequence": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSSGGCC", "length": 205, "header": "tr|A0A1L1RP46-1|A0A1L1RP46_CHICK Isoform 1 of RAB1B, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB1B PE=1 SV=2 CANONICAL=A0A1L1RP46-1" }, "locus": { "chromosome": "3", "start_pos": 10162908, "end_pos": 10151559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042588.1", "url": "https://www.ensembl.org/id/ENSGALT00010042588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025078.1", "url": "https://www.ensembl.org/id/ENSGALP00010025078.1" } ] } }, { "isoform_ac": "A0A8V0Z9E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E9/entry", "sequence": { "sequence": "LVDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSSGGCC", "length": 199, "header": "tr|A0A8V0Z9E9-1|A0A8V0Z9E9_CHICK Computationally mapped isoform of RAB1B, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB1B PE=1 SV=1 CANONICAL=A0A1L1RP46-1" }, "locus": { "chromosome": "3", "start_pos": 10156628, "end_pos": 10151559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042585.1", "url": "https://www.ensembl.org/id/ENSGALT00010042585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025075.1", "url": "https://www.ensembl.org/id/ENSGALP00010025075.1" } ] } }, { "isoform_ac": "A0A8V0Z9F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F3/entry", "sequence": { "sequence": "ATLAIPHPQCDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSSGGCC", "length": 207, "header": "tr|A0A8V0Z9F3-1|A0A8V0Z9F3_CHICK Computationally mapped isoform of RAB1B, member RAS onco family OS=Gallus gallus OX=9031 GN=RAB1B PE=1 SV=1 CANONICAL=A0A1L1RP46-1" }, "locus": { "chromosome": "3", "start_pos": 10169810, "end_pos": 10151559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042590.1", "url": "https://www.ensembl.org/id/ENSGALT00010042590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025080.1", "url": "https://www.ensembl.org/id/ENSGALP00010025080.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O18332-1", "protein_name": "Rab1", "gene_name": "Rab1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKSGCC", "length": 205 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P01123-1", "protein_name": "GTP-binding protein YPT1", "gene_name": "YPT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNVNLKGQSLTNTGGGCC", "length": 206 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P34140-1", "protein_name": "Ras-related protein Rab-1B", "gene_name": "rab1B", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTINLDGKIIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDHVSFNNVKQWMQEIQRYACDSVTRLLVGNKCDLIEKKIVDTSTAREYADSVGIPFLETSAKSSANVEQAFMIMASEIKKLQGGIQPNNNSTYNAHVVKPTGFTPIGKKKKCSII", "length": 206 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P62821-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "Rab1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC", "length": 205 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NYB7-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "Rab1A", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC", "length": 205 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SEH3-1", "protein_name": "Ras-related protein RABD2c", "gene_name": "RABD2C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWLNEIDRYASENVNKLLVGNKCDLTSQKVVSTETAKAFADELGIPFLETSAKNATNVEEAFMAMTAAIKTRMASQPAGGSKPPTVQIRGQPVNQQSGCCSS", "length": 202 }, "evidence": [ { "id": "A0A1L1RP46", "url": "https://omabrowser.org/oma/group/A0A1L1RP46/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "positive regulation of glycoprotein metabolic process", "id": "GO:1903020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "vesicle transport along microtubule", "id": "GO:0047496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "growth hormone secretion", "id": "GO:0030252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030252", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RP46", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PD87-1", "uniprot_ac": "A0A1D5PD87", "uniprot_id": "A0A1D5PD87_CHICK", "mass": { "chemical_mass": 79365.0, "monoisotopic_mass": 79365.0 }, "refseq": { "ac": "XP_015143121", "name": "striatin-3 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143121" }, "gene_names": [ { "name": "STRN3", "type": "recommended", "evidence": [ { "id": "A0A1D5PD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ] }, { "name": "STRN3", "type": "synonym", "evidence": [ { "id": "XP_015143121", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143121" } ] } ], "protein_names": [ { "name": "Striatin 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87/entry#names_and_taxonomy" } ] }, { "name": "striatin-3 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_015143121", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143121" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143121" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STRN3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87", "locus": { "chromosome": "5", "start_pos": 33768614, "end_pos": 33824070, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005526", "url": "https://www.ensembl.org/id/ENSGALG00010005526" } ] } } ], "crossref": [ { "id": "A0A1D5PD87", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PD87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040464", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423308", "url": "https://www.ncbi.nlm.nih.gov/gene/423308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423308", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SKCSQEV", "url": "https://omabrowser.org/oma/group/SKCSQEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PD87", "url": "https://www.orthodb.org/?gene=A0A1D5PD87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSR0", "url": "https://www.orthodb.org/?gene=A0A1D5PSR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TY03", "url": "https://www.orthodb.org/?gene=A0A3Q2TY03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UHY3", "url": "https://www.orthodb.org/?gene=A0A3Q2UHY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15653", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15653", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15653:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15653:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143121", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PD87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSR0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TY03", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UHY3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UHY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEHPGAGGGGGMAAAPRPQQPPPQSGGNVNLQPGGGCAGAGAGGGGQQQPQGPAAPGGQEAAGPAELSRPQHYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEVPAVPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPSSKQKGQEIKRNSGDVLETFNFLENADDSDEEEESDMIEDIAEGKEKHRINKKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGVKNHLLSCSADGTIRLWNPPEKMPCICTYNGEKEHGIPTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNNHINKVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 727, "header": "tr|A0A1D5PD87-1|A0A1D5PD87_CHICK Isoform 1 of Striatin 3 OS=Gallus gallus OX=9031 GN=STRN3 PE=1 SV=2 CANONICAL=A0A1D5PD87-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PD87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87/entry", "sequence": { "sequence": "MDEHPGAGGGGGMAAAPRPQQPPPQSGGNVNLQPGGGCAGAGAGGGGQQQPQGPAAPGGQEAAGPAELSRPQHYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEVPAVPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPSSKQKGQEIKRNSGDVLETFNFLENADDSDEEEESDMIEDIAEGKEKHRINKKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGVKNHLLSCSADGTIRLWNPPEKMPCICTYNGEKEHGIPTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNNHINKVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 727, "header": "tr|A0A1D5PD87-1|A0A1D5PD87_CHICK Isoform 1 of Striatin 3 OS=Gallus gallus OX=9031 GN=STRN3 PE=1 SV=2 CANONICAL=A0A1D5PD87-1" }, "locus": { "chromosome": "5", "start_pos": 33823871, "end_pos": 33771353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013236.1", "url": "https://www.ensembl.org/id/ENSGALT00010013236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007798.1", "url": "https://www.ensembl.org/id/ENSGALP00010007798.1" } ] } }, { "isoform_ac": "A0A1D5PSR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSR0/entry", "sequence": { "sequence": "MDEHPGAGGGGGMAAAPRPQQPPPQSGGNVNLQPGGGCAGAGAGGGGQQQPQGPAAPGGQEAAGPAELSRPQHYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEVPAVPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPSSKQKGQEIKRNSGDVLETFNFLENADDSDEEEESDMIEDIAEGKEKHRINKKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTKLQDMIADLGDDEIPHIPSGIINQSRSPSSRMTDHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGVKNHLLSCSADGTIRLWNPPEKMPCICTYNGEKEHGIPTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNNHINKVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 811, "header": "tr|A0A1D5PSR0-1|A0A1D5PD87_CHICK Computationally mapped isoform of Striatin 3 OS=Gallus gallus OX=9031 GN=STRN3 PE=1 SV=1 CANONICAL=A0A1D5PD87-1" }, "locus": { "chromosome": "5", "start_pos": 33823871, "end_pos": 33771353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013230.1", "url": "https://www.ensembl.org/id/ENSGALT00010013230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007792.1", "url": "https://www.ensembl.org/id/ENSGALP00010007792.1" } ] } }, { "isoform_ac": "A0A3Q2TY03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY03/entry", "sequence": { "sequence": "MDEHPGAGGGGGMAAAPRPQQPPPQSGGNVNLQPGGGCAGAGAGGGGQQQPQGPAAPGGQEAAGPAELSRPQHYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEVPAVPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPSSKQKGQEIKRNSGDVLETFNFLENADDSDEEEESDMIEDIAEGKEKHRINKKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKTEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGVKNHLLSCSADGTIRLWNPPEKMPCICTYNGEKEHGIPTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNNHINKVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 764, "header": "tr|A0A3Q2TY03-1|A0A3Q2TY03_CHICK Computationally mapped isoform of Striatin 3 OS=Gallus gallus OX=9031 GN=STRN3 PE=1 SV=1 CANONICAL=A0A1D5PD87-1" }, "locus": { "chromosome": "5", "start_pos": 33823871, "end_pos": 33771353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013222.1", "url": "https://www.ensembl.org/id/ENSGALT00010013222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007785.1", "url": "https://www.ensembl.org/id/ENSGALP00010007785.1" } ] } }, { "isoform_ac": "A0A3Q2UHY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHY3/entry", "sequence": { "sequence": "MDEHPGAGGGGGMAAAPRPQQPPPQSGGNVNLQPGGGCAGAGAGGGGQQQPQGPAAPGGQEAAGPAELSRPQHYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEVPAVPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPSSKQKGQEIKRNSGDVLETFNFLENADDSDEEEESDMIEDIAEGKEKHRINKKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWGVNRTKLQDMIADLGDDEIPHIPSGIINQSRSPSSRMTDHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGVKNHLLSCSADGTIRLWNPPEKMPCICTYNGEKEHGIPTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNNHINKVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 774, "header": "tr|A0A3Q2UHY3-1|A0A1D5PD87_CHICK Computationally mapped isoform of Striatin 3 OS=Gallus gallus OX=9031 GN=STRN3 PE=1 SV=1 CANONICAL=A0A1D5PD87-1" }, "locus": { "chromosome": "5", "start_pos": 33823871, "end_pos": 33771353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013233.1", "url": "https://www.ensembl.org/id/ENSGALT00010013233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007795.1", "url": "https://www.ensembl.org/id/ENSGALP00010007795.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423308", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPF1-1", "protein_name": "Striatin-3", "gene_name": "STRN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDELAGGGGGGPGMAAPPRQQQGPGGNMSLSSGGNGAAGSGGPPAAEGAGPATGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPAFESEETKDTEAPTAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQESKRPSGDVLETFNFLENADDSDEEEENDMIEGIPEGKDKHRINKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYEPNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCICTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSTVIYDLETSQSLVMLSSQIESGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 713 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5D7H2-1", "protein_name": "Striatin-3", "gene_name": "STRN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDELAGGGGGGPAMASPPRQQQGPGGNMSLSPGGNGAAGGGGPPATEGAGPAAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKRTSGDVLETFNFLENADDSDEEEENDMIEGIPEGKDKHRINKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTTEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTKLYDTIADLGDDELPLIPSGIINQSRSASTRMTDHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGTDATIQWWNMPSPNVDPYDTYEPNVLAGTLIAHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSTVIYDLETSQSLVMLSSQMDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 797 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P58405-1", "protein_name": "Striatin-3", "gene_name": "Strn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDELAGGGGGQGMAVPPRPQQGPGGNLSLPPGANGAPGGGGPPAAETAGPPAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDAEAPPAQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSIEAKNLEQILNGGESPKQKGQEIKRPSGDVLETFNFLENADDSDEEENDMIEGIPEGKDKLRIHKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLMSKLKEQYKKERKGKRGAKRVNRTNLCDMITDLGDDELPHIPSGIINQSRSASTRMTDHEGSRAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDALRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESHVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCICTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAIIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 794 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13033-1", "protein_name": "Striatin-3", "gene_name": "STRN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDELAGGGGGGPGMAAPPRQQQGPGGNLGLSPGGNGAAGGGGPPASEGAGPAAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVETKNLEQILNGGESPKQKGQEIKRSSGDVLETFNFLENADDSDEDEENDMIEGIPEGKDKHRMNKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRANRTKLYDMIADLGDDELPHIPSGIINQSRSASTRMTDHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHSSKAYIASAGADALAKVFV", "length": 797 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54J37-1", "protein_name": "Striatin homolog", "gene_name": "strn", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNQNNNNALANGDSQFTMPKVIDYLQNEWLKFEVDRAHWISEKAELTNRILKLESERKLFESHKFDLCRRVKMLEYALQQERLKNNSLLQQQQKVIEKVEEEEEEDDKIPKNREPPKKSKDNTTRLIIRKYLREMGYNDLIVSKSLQTEFENDSQNIDNDTTNTIDDTNDTTVKTILNLKDINNNNSNNNNKNQTTTTTTTSPSPSPSPSTSTSTSTSSNKTDNTTTTTTNGNGYNSNTIISPPSSSSSSSSSSSSSSSQSQPQPQLQSSLSELINNTTDLSQSLDSLSSASSGYEYDSLLDNLKQLDNSSVSSNSGNNSINSSSDSLDTSKQSQEDPNNVTISKQQQQEQQQQQESDEQSFNSFNEDIFNKLTANSKGRMKIKGLGNLKNYKKEHMGEEGNLSLPDQNTEEKSTPTTKSSSSSSSSSTGSTRKKKSSSSSSSGSSSSNSNTMNSELMGLGASDLNDITLDDGSKGGNDSAAPRVWKFKHSLKSHFDGVRSIQFHPNEPIMISASEDNSIKVWNLNHLVPTKKSPSPEIEPLYTIRGHTGPVFTSEWNQINGEYSNYQSFFSAGYDMIIRQWSLPSSDIDSYLQHGKILPYLEKEFIGGHQDGIWDLLSIPNTPNLLSSSADGTVSLWNTTTSEQLYTLQHSNGLSYIPTSIALPATENNRKLLTSYNDGSILLFDLETQQIISQLKQGSSNNNNNNNNNSQINKIVSHPFMPLAMTGSEDHKIEFFDLNSNTVVHSMIAHSNSISSLTIDPSGLYIASCAHDSSIRFWDISSKTCIQDLNSHRPKYDESIHCIKYHPNKGYFASGGADSVIRILN", "length": 827 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9ERG2-1", "protein_name": "Striatin-3", "gene_name": "Strn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELAGGGGGGQGMAAPPRPQQGPGGNLSLPPGANGAPGGGGPPAAEAAGPPAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDVEAPPAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVEAKNLEQILNGGESPKQKGQEIKRPPGDVLETFNFLENADDSDEEENDMIEGIPEGKDKLRIHKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTNLCDMITDLGDDELPHIPSGIINQSRSASTRMADHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV", "length": 796 }, "evidence": [ { "id": "A0A1D5PD87", "url": "https://omabrowser.org/oma/group/A0A1D5PD87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "protein phosphatase 2A binding", "id": "GO:0051721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "armadillo repeat domain binding", "id": "GO:0070016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070016", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" }, { "name": "negative regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033147", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PD87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PD87-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 727, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PD87-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PD87" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD87" }, { "id": "PF08232", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Striatin N-terminal", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 204, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 640, "end_pos": 642 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJG4-1", "uniprot_ac": "A0A1D5PJG4", "uniprot_id": "A0A1D5PJG4_CHICK", "mass": { "chemical_mass": 62677.0, "monoisotopic_mass": 62677.0 }, "refseq": { "ac": "NP_001382918", "name": "heterogeneous nuclear ribonucleoprotein Q", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382918" }, "gene_names": [ { "name": "SYNCRIP", "type": "recommended", "evidence": [ { "id": "A0A1D5PJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ] }, { "name": "SYNCRIP", "type": "synonym", "evidence": [ { "id": "NP_001382918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382918" } ] } ], "protein_names": [ { "name": "Synaptotagmin binding cytoplasmic RNA interacting protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein Q", "type": "synonym", "evidence": [ { "id": "NP_001382918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382918" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01040045.1, SRR13267661.13287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ456924.1, HAEK01011522.1, BU121253.1, BU127152.1, AJ719757.1, BU409030.1, HAEK01028976.1 and AL586038.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001382918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382918" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNCRIP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4", "locus": { "chromosome": "3", "start_pos": 76647690, "end_pos": 76577431, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004210", "url": "https://www.ensembl.org/id/ENSGALG00010004210" } ] } } ], "crossref": [ { "id": "A0A1D5PJG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015830", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015830", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12483", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12483", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12495", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12495", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421831", "url": "https://www.ncbi.nlm.nih.gov/gene/421831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJG4", "url": "https://www.orthodb.org/?gene=A0A1D5PJG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAF8", "url": "https://www.orthodb.org/?gene=A0A3Q2UAF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XC74", "url": "https://www.orthodb.org/?gene=A0A8V0XC74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XIZ6", "url": "https://www.orthodb.org/?gene=A0A8V0XIZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XND2", "url": "https://www.orthodb.org/?gene=A0A8V0XND2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZU2", "url": "https://www.orthodb.org/?gene=F1NZU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001382918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XND2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XND2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZU2", "url": "https://www.uniprot.org/uniprotkb/F1NZU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZU2-1", "url": "https://www.uniprot.org/uniprotkb/F1NZU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ", "length": 562, "header": "tr|A0A1D5PJG4-1|A0A1D5PJG4_CHICK Isoform 1 of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ", "length": 562, "header": "tr|A0A1D5PJG4-1|A0A1D5PJG4_CHICK Isoform 1 of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76599795, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009830.1", "url": "https://www.ensembl.org/id/ENSGALT00010009830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005736.1", "url": "https://www.ensembl.org/id/ENSGALP00010005736.1" } ] } }, { "isoform_ac": "A0A3Q2UAF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAF8/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSENQEFYQDSFGQQWK", "length": 623, "header": "tr|A0A3Q2UAF8-1|A0A1D5PJG4_CHICK Computationally mapped isoform of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76597896, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009834.1", "url": "https://www.ensembl.org/id/ENSGALT00010009834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005740.1", "url": "https://www.ensembl.org/id/ENSGALP00010005740.1" } ] } }, { "isoform_ac": "A0A8V0XC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC74/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSAGKRGRGRS", "length": 610, "header": "tr|A0A8V0XC74-1|A0A1D5PJG4_CHICK Computationally mapped isoform of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76599782, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009825.1", "url": "https://www.ensembl.org/id/ENSGALT00010009825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005731.1", "url": "https://www.ensembl.org/id/ENSGALP00010005731.1" } ] } }, { "isoform_ac": "A0A8V0XIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIZ6/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGAQQQRGRGQGKGVEAGPDLLQ", "length": 548, "header": "tr|A0A8V0XIZ6-1|A0A1D5PJG4_CHICK Computationally mapped isoform of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76599795, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009832.1", "url": "https://www.ensembl.org/id/ENSGALT00010009832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005738.1", "url": "https://www.ensembl.org/id/ENSGALP00010005738.1" } ] } }, { "isoform_ac": "A0A8V0XND2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND2/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQVLCLVTVVWNMSGTLHNTDLLQFSAPG", "length": 456, "header": "tr|A0A8V0XND2-1|A0A1D5PJG4_CHICK Computationally mapped isoform of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=1 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76598618, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009821.1", "url": "https://www.ensembl.org/id/ENSGALT00010009821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005727.1", "url": "https://www.ensembl.org/id/ENSGALP00010005727.1" } ] } }, { "isoform_ac": "F1NZU2-1", "url": "https://www.uniprot.org/uniprotkb/F1NZU2/entry", "sequence": { "sequence": "MATEHVNGNGTEEPMDTSAAVTHSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYAQRGGPGSARGVRGARGGAQQQRGRGQGKGVEAGPDLLQ", "length": 448, "header": "tr|F1NZU2-1|A0A1D5PJG4_CHICK Computationally mapped isoform of Synaptotagmin binding cytoplasmic RNA interacting protein OS=Gallus gallus OX=9031 GN=SYNCRIP PE=1 SV=2 CANONICAL=A0A1D5PJG4-1" }, "locus": { "chromosome": "3", "start_pos": 76599795, "end_pos": 76578815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009828.1", "url": "https://www.ensembl.org/id/ENSGALT00010009828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005734.1", "url": "https://www.ensembl.org/id/ENSGALP00010005734.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "GAIT complex", "id": "GO:0097452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097452", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stability complex", "id": "GO:0070937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070937", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stabilization", "id": "GO:0070934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070934", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "cellular response to type II interferon", "id": "GO:0071346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071346", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900152", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJG4" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 241, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 90, "end_pos": 92 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZT9-1", "uniprot_ac": "A0A1D5PZT9", "uniprot_id": "A0A1D5PZT9_CHICK", "mass": { "chemical_mass": 87565.0, "monoisotopic_mass": 87565.0 }, "refseq": { "ac": "XP_426046", "name": "cadherin-18 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426046" }, "gene_names": [ { "name": "CDH18", "type": "recommended", "evidence": [ { "id": "A0A1D5PZT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ] }, { "name": "CDH18", "type": "synonym", "evidence": [ { "id": "XP_426046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426046" } ] } ], "protein_names": [ { "name": "Cadherin 18", "type": "synonym", "evidence": [ { "id": "A0A1D5PZT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9/entry#names_and_taxonomy" } ] }, { "name": "cadherin-18 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_426046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426046" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_426046.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426046" } ] }, { "annotation": "Cadherins are calcium-dependent cell adhesion proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X6G9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G9#function" }, { "database": "UniProtKB", "id": "RU004357", "url": "https://www.uniprot.org/uniprotkb/RU004357#function" }, { "database": "UniProtKB", "id": "A0A1D5PKP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKP1#function" }, { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDH18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9", "locus": { "chromosome": "2", "start_pos": 74113373, "end_pos": 73861053, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000814", "url": "https://www.ensembl.org/id/ENSGALG00010000814" } ] } } ], "crossref": [ { "id": "A0A1D5PZT9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036097", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036097", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428490", "url": "https://www.ncbi.nlm.nih.gov/gene/428490", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKP1", "url": "https://www.orthodb.org/?gene=A0A1D5PKP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZT9", "url": "https://www.orthodb.org/?gene=A0A1D5PZT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X6G9", "url": "https://www.orthodb.org/?gene=A0A8V0X6G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_426046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X6G9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X6G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRITSTCCICPVLVCLCFVQRCYGAAHHGSIKVTRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSEMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMKYTIINGDGAGVFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDVTMLKIIVGDVDEPPLFTMPSYVMEVYENAKIGTAVGTVTAQDPDTANSLVRYFIDHNTEEDRYFTIDANTGTIKTAKIFDREETPWYNITVAASEIDNPGLVSHVPVGIRILDVNDNPPELAREYDVVVCENAKPGQVIQTITATDKDNSANGARFHFSLDEGLSLNPNFTLRDNEDNTASILTRRRRYSRTIQDIYYLPILISDGGVPPLSSSSTLTVRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVVILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDVRPEVKPAPRHHPSSSLDSINVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGHRSEAGSISSLDSVTTQSDQDYNYLGDWGPEFKKLAELYGEIESERTT", "length": 790, "header": "tr|A0A1D5PZT9-1|A0A1D5PZT9_CHICK Isoform 1 of Cadherin 18 OS=Gallus gallus OX=9031 GN=CDH18 PE=4 SV=1 CANONICAL=A0A1D5PZT9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKP1/entry", "sequence": { "sequence": "MRITSTCCICPVLVCLCFVQRCYGAAHHGSIKVTRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSEMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMKYTIINGDGAGVFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDVTMLKIIVGDVDEPPLFTMPSYVMEVYENAKIGTAVGTVTAQDPDTANSLVRYFIDHNTEEDRYFTIDANTGTIKTAKIFDREETPWYNITVAASEIGLCKAVPESRNGPTTGHRTSAVCGALIYSGDNPGLVSHVPVGIRILDVNDNPPELAREYDVVVCENAKPGQVIQTITATDKDNSANGARFHFSLDEGLSLNPNFTLRDNEDNTASILTRRRRYSRTIQDIYYLPILISDGGVPPLSSSSTLTVRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVVILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDVRPEVKPAPRHHPSSSLDSINVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGHRSEAGSISSLDSVTTQSDQDYNYLGDWGPEFKKLAELYGEIESERTT", "length": 820, "header": "tr|A0A1D5PKP1-1|A0A1D5PZT9_CHICK Computationally mapped isoform of Cadherin 18 OS=Gallus gallus OX=9031 GN=CDH18 PE=4 SV=1 CANONICAL=A0A1D5PZT9-1" }, "locus": { "chromosome": "2", "start_pos": 74113095, "end_pos": 73949270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001794.1", "url": "https://www.ensembl.org/id/ENSGALT00010001794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000995.1", "url": "https://www.ensembl.org/id/ENSGALP00010000995.1" } ] } }, { "isoform_ac": "A0A1D5PZT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9/entry", "sequence": { "sequence": "MRITSTCCICPVLVCLCFVQRCYGAAHHGSIKVTRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSEMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMKYTIINGDGAGVFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDVTMLKIIVGDVDEPPLFTMPSYVMEVYENAKIGTAVGTVTAQDPDTANSLVRYFIDHNTEEDRYFTIDANTGTIKTAKIFDREETPWYNITVAASEIDNPGLVSHVPVGIRILDVNDNPPELAREYDVVVCENAKPGQVIQTITATDKDNSANGARFHFSLDEGLSLNPNFTLRDNEDNTASILTRRRRYSRTIQDIYYLPILISDGGVPPLSSSSTLTVRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVVILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDVRPEVKPAPRHHPSSSLDSINVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGHRSEAGSISSLDSVTTQSDQDYNYLGDWGPEFKKLAELYGEIESERTT", "length": 790, "header": "tr|A0A1D5PZT9-1|A0A1D5PZT9_CHICK Isoform 1 of Cadherin 18 OS=Gallus gallus OX=9031 GN=CDH18 PE=4 SV=1 CANONICAL=A0A1D5PZT9-1" }, "locus": { "chromosome": "2", "start_pos": 74113095, "end_pos": 73949270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001795.1", "url": "https://www.ensembl.org/id/ENSGALT00010001795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000996.1", "url": "https://www.ensembl.org/id/ENSGALP00010000996.1" } ] } }, { "isoform_ac": "A0A8V0X6G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G9/entry", "sequence": { "sequence": "MRITSTCCICPVLVCLCFVQRCYGAAHHGSIKVTRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSEMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMKYTIINGDGAGVFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDVTMLKIIVGDVDEPPLFTMPSYVMEVYENAKIGTAVGTVTAQDPDTANSLVRYFIDHNTEEDRYFTIDANTGTIKTAKIFDREETPWYNITVAASEIDNPGLVSHVPVGIRILDVNDNPPELAREYDVVVCENAKPGQVIQTITATDKDNSANGARFHFSLDEGLSLNPNFTLRDNEDNTASILTRRRRYSRTIQDIYYLPILISDGGVPPLSSSSTLTVRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVVILLVFSLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDVRPEVKPAPRHHPSSSLDSINVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGHRSEAGSISSLDSVTTQSDQDYNYLGDWGPEFKKLAELYGEIESERTT", "length": 794, "header": "tr|A0A8V0X6G9-1|A0A1D5PZT9_CHICK Computationally mapped isoform of Cadherin 18 OS=Gallus gallus OX=9031 GN=CDH18 PE=4 SV=1 CANONICAL=A0A1D5PZT9-1" }, "locus": { "chromosome": "2", "start_pos": 74113095, "end_pos": 73949270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001793.1", "url": "https://www.ensembl.org/id/ENSGALT00010001793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000994.1", "url": "https://www.ensembl.org/id/ENSGALP00010000994.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZT9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PZT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZT9" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 159, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 255, "end_pos": 257 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PVC9-1", "uniprot_ac": "A0A1D5PVC9", "uniprot_id": "A0A1D5PVC9_CHICK", "mass": { "chemical_mass": 29007.0, "monoisotopic_mass": 29007.0 }, "refseq": { "ac": "XP_419614", "name": "parkin coregulated gene protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419614" }, "gene_names": [ { "name": "PACRG", "type": "recommended", "evidence": [ { "id": "A0A1D5PVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ] }, { "name": "PACRG", "type": "synonym", "evidence": [ { "id": "XP_419614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419614" } ] } ], "protein_names": [ { "name": "Parkin coregulated", "type": "synonym", "evidence": [ { "id": "A0A1D5PVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9/entry#names_and_taxonomy" } ] }, { "name": "parkin coregulated gene protein", "type": "synonym", "evidence": [ { "id": "XP_419614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419614" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_419614.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PACRG", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9", "locus": { "chromosome": "3", "start_pos": 43967805, "end_pos": 44161303, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006068", "url": "https://www.ensembl.org/id/ENSGALG00010006068" } ] } } ], "crossref": [ { "id": "A0A1D5PVC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011560", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011560", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421576", "url": "https://www.ncbi.nlm.nih.gov/gene/421576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421576", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INGPIHE", "url": "https://omabrowser.org/oma/group/INGPIHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVC9", "url": "https://www.orthodb.org/?gene=A0A1D5PVC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPB1", "url": "https://www.orthodb.org/?gene=A0A8V0XPB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPB6", "url": "https://www.orthodb.org/?gene=A0A8V0XPB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XWX2", "url": "https://www.orthodb.org/?gene=A0A8V0XWX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21207:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21207:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVEEAGCGPAKPAGNRRPQKQEPLGHVKKTKQQVSDGFTVKAMMKNTVVRGPPLAGAFKERPTKPTAFRKFYERGDFPIAIEHDTKGNRIAWKVEIEKLDYHYYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGENKILPVIPQLIIPIKNALSLRNRQVICITLKVLQHLVVSADMVGEALVPYYRQILPVLNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGETAYINIKYMIPTYQSCILN", "length": 254, "header": "tr|A0A1D5PVC9-1|A0A1D5PVC9_CHICK Isoform 1 of Parkin coregulated OS=Gallus gallus OX=9031 GN=PACRG PE=1 SV=1 CANONICAL=A0A1D5PVC9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9/entry", "sequence": { "sequence": "MVVEEAGCGPAKPAGNRRPQKQEPLGHVKKTKQQVSDGFTVKAMMKNTVVRGPPLAGAFKERPTKPTAFRKFYERGDFPIAIEHDTKGNRIAWKVEIEKLDYHYYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGENKILPVIPQLIIPIKNALSLRNRQVICITLKVLQHLVVSADMVGEALVPYYRQILPVLNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGETAYINIKYMIPTYQSCILN", "length": 254, "header": "tr|A0A1D5PVC9-1|A0A1D5PVC9_CHICK Isoform 1 of Parkin coregulated OS=Gallus gallus OX=9031 GN=PACRG PE=1 SV=1 CANONICAL=A0A1D5PVC9-1" }, "locus": { "chromosome": "3", "start_pos": 44159977, "end_pos": 43969000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014514.1", "url": "https://www.ensembl.org/id/ENSGALT00010014514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008531.1", "url": "https://www.ensembl.org/id/ENSGALP00010008531.1" } ] } }, { "isoform_ac": "A0A8V0XPB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB1/entry", "sequence": { "sequence": "RRARGPAGGTGVRGSARGERSPRADSRPLRGDGSGGSGLRPRQARGEQASPEAGAAGTREENQAAVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGETAYINIKYMIPTYQSCILN", "length": 118, "header": "tr|A0A8V0XPB1-1|A0A1D5PVC9_CHICK Computationally mapped isoform of Parkin coregulated OS=Gallus gallus OX=9031 GN=PACRG PE=1 SV=1 CANONICAL=A0A1D5PVC9-1" }, "locus": { "chromosome": "3", "start_pos": 44160248, "end_pos": 43969000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014513.1", "url": "https://www.ensembl.org/id/ENSGALT00010014513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008530.1", "url": "https://www.ensembl.org/id/ENSGALP00010008530.1" } ] } }, { "isoform_ac": "A0A8V0XPB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB6/entry", "sequence": { "sequence": "MRTNSLLLHVAASKHHARPRKRHGQIVRVPILARCGEMVVEEAGCGPAKPAGNRRPQKQEPLGHVKKTKQQVSDGFTVKAMMKNTVVRGPPLAGAFKERPTKPTAFRKFYERGDFPIAIEHDTKGNRIAWKVEIEKLDYHYYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGENKILPVIPQLIIPIKNALSLRNRQVICITLKVLQHLVVSADMVGEALVPYYRQILPVLNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGETAYINIKYMIPTYQSCILN", "length": 291, "header": "tr|A0A8V0XPB6-1|A0A1D5PVC9_CHICK Computationally mapped isoform of Parkin coregulated OS=Gallus gallus OX=9031 GN=PACRG PE=1 SV=1 CANONICAL=A0A1D5PVC9-1" }, "locus": { "chromosome": "3", "start_pos": 44161104, "end_pos": 43969000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014519.1", "url": "https://www.ensembl.org/id/ENSGALT00010014519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008536.1", "url": "https://www.ensembl.org/id/ENSGALP00010008536.1" } ] } }, { "isoform_ac": "A0A8V0XWX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWX2/entry", "sequence": { "sequence": "MRTNSLLLHVAASKHHARPRKRHGQIVRVPILARCGEMVVEEAGCGPAKPAGNRRPQKQEPLGHVKKTKQQVSDGFTVKAMMKNTVVEIEKLDYHYYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGENKILPVIPQLIIPIKNALSLRNRQVICITLKVLQHLVVSADMVGEALVPYYRQILPVLNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGETAYINIKYMIPTYQSCILN", "length": 246, "header": "tr|A0A8V0XWX2-1|A0A1D5PVC9_CHICK Computationally mapped isoform of Parkin coregulated OS=Gallus gallus OX=9031 GN=PACRG PE=1 SV=1 CANONICAL=A0A1D5PVC9-1" }, "locus": { "chromosome": "3", "start_pos": 44161104, "end_pos": 43969000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014516.1", "url": "https://www.ensembl.org/id/ENSGALT00010014516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008533.1", "url": "https://www.ensembl.org/id/ENSGALP00010008533.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421576", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AL41-1", "protein_name": "Parkin coregulated", "gene_name": "PACRG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVAEKETLSLSKCPDKMPKRTKLLAQQPLPVHQPHPLVSEGFTVKAMMKNSVVRGPPTAGAFKERPTKPTAFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGNKILPVIPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGEALVPYYRQILPILNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGEDAFINIKYMVPTYESCLLN", "length": 257 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AHI9-1", "protein_name": "Parkin coregulated", "gene_name": "Pacrg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAEKETLTLNKCPDKMPKRTKLLPQQTIQVHQPHSLVSEGFTVKAMMKNSVVRGPPAAGAFKERPTKPTAFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGNKILPVIPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGEALVPYYRQILPILNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGEDAFINIKYMVPTYESCLLN", "length": 257 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1ZBM4-1", "protein_name": "Parkin coregulated gene protein homolog", "gene_name": "Dmel\\CG15120", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMAQTARTATARRPTHDYHRPTRSKSANPAQLRPLSGIHGAAVSSRPRYVPPFSIQSQQKNTVVIDGPIHETAPKTASARSRVPNPKILRRQQKSMSTFNLGMGLNGCSTGGANDPGRGTLFRMYFDRGDLPIKMEYLCGGDKIGWTVDIEKLDYSLYLPLFFDGLAETKHPYKTYARQGVTDLLLAGGEKIHPVIPQLILPLKNALSTRNLEVMCTTLKIIQQLVMSSDLVGPALVPFYRQLLPMFNAFKVKNLNCGDEIDYAQKNNLNLGDLIDETLQVLELHGGEDAFINIKYMVPTYESCYLN", "length": 308 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A5PK71-1", "protein_name": "Parkin coregulated gene protein", "gene_name": "PACRG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVAEKETLSLNKCPAKLPTRTKLLAQQPLPVHQPHSLVSEGFTVKAMMKNSVVRGPPSAGAFKERPTKPTAFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGNKILPVIPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGEALVPYYRQILPILNIFKNKNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGEDAFINIKYMVPTYESCLLN", "length": 257 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96M98-1", "protein_name": "Parkin coregulated gene protein", "gene_name": "PACRG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAEKETLSLNKCPDKMPKRTKLLAQQPLPVHQPHSLVSEGFTVKAMMKNSVVRGPPAAGAFKERPTKPTAFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGNKILPVLPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGKALVPYYRQILPVLNIFKNMNGSYSLPRLECSGAIMARCNLDHLGSSDPPTSASQVAEIIVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGENAFINIKYVVPTYESCLLN", "length": 296 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAK2-1", "protein_name": "Parkin coregulated gene protein homolog", "gene_name": "Pacrg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKRTKLLPQQTFQVHQPRSLVSEGFTVKAMMKNSVVRGPPVAGAFKERPAKPTTFRKCYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLSEMTFPYEFFARRGIHDMLEHGGNKILPVIPQLIIPIKNALNLRNRQIICVTLKVLQHLVVSSEMVGEALLPYYRQILPILNIFKNMNVNSGDGIDYSQQKRENIGDLIQETLEAFERYGGEDAFINIKYMVPTYESCLLN", "length": 241 }, "evidence": [ { "id": "A0A1D5PVC9", "url": "https://omabrowser.org/oma/group/A0A1D5PVC9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "axonemal B tubule inner sheath", "id": "GO:0160112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160112", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PDW3-1", "uniprot_ac": "A0A1D5PDW3", "uniprot_id": "A0A1D5PDW3_CHICK", "mass": { "chemical_mass": 15628.0, "monoisotopic_mass": 15628.0 }, "refseq": { "ac": "XP_015154774", "name": "protein FAM107B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154774" }, "gene_names": [ { "name": "FAM107B", "type": "recommended", "evidence": [ { "id": "A0A1D5PDW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3" } ] }, { "name": "FAM107B", "type": "synonym", "evidence": [ { "id": "XP_015154774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154774" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 107 member B", "type": "synonym", "evidence": [ { "id": "A0A1D5PDW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM107B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154774" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154774" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM107B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3", "locus": { "chromosome": "1", "start_pos": 7880749, "end_pos": 7943999, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005879", "url": "https://www.ensembl.org/id/ENSGALG00010005879" } ] } } ], "crossref": [ { "id": "A0A1D5PDW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033226", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426376", "url": "https://www.ncbi.nlm.nih.gov/gene/426376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DTMMSMS", "url": "https://omabrowser.org/oma/group/DTMMSMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 132, "header": "tr|A0A1D5PDW3-1|A0A1D5PDW3_CHICK Isoform 1 of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=2 CANONICAL=A0A1D5PDW3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3/entry", "sequence": { "sequence": "MAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 132, "header": "tr|A0A1D5PDW3-1|A0A1D5PDW3_CHICK Isoform 1 of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=2 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7889853, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014068.1", "url": "https://www.ensembl.org/id/ENSGALT00010014068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008285.1", "url": "https://www.ensembl.org/id/ENSGALP00010008285.1" } ] } }, { "isoform_ac": "A0A8V0XJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJD4/entry", "sequence": { "sequence": "MPNSFTGKIHTRVLPAWQKEDPVSICSDTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 178, "header": "tr|A0A8V0XJD4-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7896094, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014058.1", "url": "https://www.ensembl.org/id/ENSGALT00010014058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008278.1", "url": "https://www.ensembl.org/id/ENSGALP00010008278.1" } ] } }, { "isoform_ac": "A0A8V0XJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJE4/entry", "sequence": { "sequence": "MFLELNVIHFPVSAESNSKEEKYWCCWHSVTTDGSRRVPVSMTSRLWSALWDTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 202, "header": "tr|A0A8V0XJE4-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7933154, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014071.1", "url": "https://www.ensembl.org/id/ENSGALT00010014071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008288.1", "url": "https://www.ensembl.org/id/ENSGALP00010008288.1" } ] } }, { "isoform_ac": "A0A8V0XNK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK3/entry", "sequence": { "sequence": "MNTPDTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 155, "header": "tr|A0A8V0XNK3-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7927324, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014065.1", "url": "https://www.ensembl.org/id/ENSGALT00010014065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008282.1", "url": "https://www.ensembl.org/id/ENSGALP00010008282.1" } ] } }, { "isoform_ac": "A0A8V0XQT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT8/entry", "sequence": { "sequence": "MLGSSSSNRKRKRSHSQVNELTRRPNALGTRLETTRDDTTSTARTGARPAPGARPVALTADGDSRALRAHLRADSGPAGSPSPSPLSLSALFSLSFPLALLPPAPDNKDNAGLGPGAAPAVTQRQTRPRPAPPRRSLRRGRDRAARVAGPCRHSASGRVPRSLLRSLLPSRGLSPLVPRGEPPRRDTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 336, "header": "tr|A0A8V0XQT8-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7942010, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014078.1", "url": "https://www.ensembl.org/id/ENSGALT00010014078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008295.1", "url": "https://www.ensembl.org/id/ENSGALP00010008295.1" } ] } }, { "isoform_ac": "A0A8V0XTH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTH9/entry", "sequence": { "sequence": "MTSRLWSALWDTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 161, "header": "tr|A0A8V0XTH9-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7932644, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014074.1", "url": "https://www.ensembl.org/id/ENSGALT00010014074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008291.1", "url": "https://www.ensembl.org/id/ENSGALP00010008291.1" } ] } }, { "isoform_ac": "A0A8V0XW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW67/entry", "sequence": { "sequence": "MTFYTVSKDTEPKDPFPIPRKIMAEPDYIDDDNPELIRPQKLINPVKSSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQQKEEEAQKKKSDLEIELLKRQQKLEQLELEQQKIQEEQENAPEFVKVKGNLRRTVQEAAEAPDS", "length": 154, "header": "tr|A0A8V0XW67-1|A0A1D5PDW3_CHICK Computationally mapped isoform of Family with sequence similarity 107 member B OS=Gallus gallus OX=9031 GN=FAM107B PE=1 SV=1 CANONICAL=A0A1D5PDW3-1" }, "locus": { "chromosome": "1", "start_pos": 7909044, "end_pos": 7883822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014062.1", "url": "https://www.ensembl.org/id/ENSGALT00010014062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008279.1", "url": "https://www.ensembl.org/id/ENSGALP00010008279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9VIJ3-1", "protein_name": "Protein FAM107B", "gene_name": "BcDNA:SD01241", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQRPSSNISSNIMNRMSIFENTAFRHSLADADNAAGTMMSMTSSPPATPTGVQTDSDGLILPKKLINPCMENIDRKELHRELKFNARVGKSVLNQKSELQRAYDKQKERHAAAEQHSPDADIVGGIPGLKGELGRVIMERAQKHEAAAQKQDQEDAEERQYVNPEYLNVRAKLRTAHANN", "length": 180 }, "evidence": [ { "id": "A0A1D5PDW3", "url": "https://omabrowser.org/oma/group/A0A1D5PDW3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PPI7-1", "uniprot_ac": "A0A1D5PPI7", "uniprot_id": "A0A1D5PPI7_CHICK", "mass": { "chemical_mass": 12560.0, "monoisotopic_mass": 12560.0 }, "refseq": { "ac": "XP_003640629", "name": "ribosomal protein 63, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640629" }, "gene_names": [ { "name": "MRPL57", "type": "recommended", "evidence": [ { "id": "A0A1D5PPI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7" } ] }, { "name": "MRPL57", "type": "synonym", "evidence": [ { "id": "XP_003640629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640629" } ] } ], "protein_names": [ { "name": "Mitochondrial ribosomal protein L57", "type": "synonym", "evidence": [ { "id": "A0A1D5PPI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein 63, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003640629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640629" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPI7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7", "locus": {} } ], "crossref": [ { "id": "A0A1D5PPI7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039783", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039783", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771615", "url": "https://www.ncbi.nlm.nih.gov/gene/771615", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771615", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771615", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEFGHAA", "url": "https://omabrowser.org/oma/group/QEFGHAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPI7", "url": "https://www.orthodb.org/?gene=A0A1D5PPI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHF0", "url": "https://www.orthodb.org/?gene=A0A8V0XHF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XRM2", "url": "https://www.orthodb.org/?gene=A0A8V0XRM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XRN1", "url": "https://www.orthodb.org/?gene=A0A8V0XRN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13082:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13082:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14520", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14520", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14520:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14520:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003640629", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLTLALLRKRIPGKQWIGKYRRPRVVTTTMKQAMIRRLEIEAENEYWLSRPYLTRQEECNHNREARVARWEAFKALKSSKFPEHRYMSDHLNHLNVSKKWTS", "length": 103, "header": "tr|A0A1D5PPI7-1|A0A1D5PPI7_CHICK Isoform 1 of Mitochondrial ribosomal protein L57 OS=Gallus gallus OX=9031 GN=MRPL57 PE=4 SV=1 CANONICAL=A0A1D5PPI7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7/entry", "sequence": { "sequence": "MFLTLALLRKRIPGKQWIGKYRRPRVVTTTMKQAMIRRLEIEAENEYWLSRPYLTRQEECNHNREARVARWEAFKALKSSKFPEHRYMSDHLNHLNVSKKWTS", "length": 103, "header": "tr|A0A1D5PPI7-1|A0A1D5PPI7_CHICK Isoform 1 of Mitochondrial ribosomal protein L57 OS=Gallus gallus OX=9031 GN=MRPL57 PE=4 SV=1 CANONICAL=A0A1D5PPI7-1" }, "locus": { "chromosome": "1", "start_pos": 178473524, "end_pos": 178473216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013001.1", "url": "https://www.ensembl.org/id/ENSGALT00010013001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007563.1", "url": "https://www.ensembl.org/id/ENSGALP00010007563.1" } ] } }, { "isoform_ac": "A0A8V0XHF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHF0/entry", "sequence": { "sequence": "VKPFLLTSDLKLSSVNPTLPQIRTSGSGLSGGDPLGSSTHPALPQSAQTRLERGLTPTAGAQQPPQSATLLPPGSTARFEPPSPSADADHPPTQPPSHLSRAPSSGQQACAHRRLRSTIARTVRAPRDIRAVCCGTRWRWSRASRRRRSRRNRRSRSTGRRRVRCCSASSPPTTGGTTAWTSSPAATCPPASCRSTPGTMFLTLALLRKRIPGKQWIGKYRRPRVVTTTMKQAMIRRLEIEAENEYWLSRPYLTRQEECNHNREARVARWEAFKALKSSKFPEHRYMSDHLNHLNVSKKWTS", "length": 302, "header": "tr|A0A8V0XHF0-1|A0A1D5PPI7_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein L57 OS=Gallus gallus OX=9031 GN=MRPL57 PE=4 SV=1 CANONICAL=A0A1D5PPI7-1" }, "locus": { "chromosome": "1", "start_pos": 178492654, "end_pos": 178473216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012996.1", "url": "https://www.ensembl.org/id/ENSGALT00010012996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007558.1", "url": "https://www.ensembl.org/id/ENSGALP00010007558.1" } ] } }, { "isoform_ac": "A0A8V0XRM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRM2/entry", "sequence": { "sequence": "MICLQTLRGKNSSAHPHGRPERQRGGVLTEDPTVPSPAQARPVLAGSARGGRREPEARLAGLAGRAVPQRPAHTARPARPFGLGPLPPWGGGDAREAVPALTRVLPVQRPLQLLRLFLYREGQGAQFAEEVPRHVHRPRGRERRVRKHGAATAAASGALTRSRSPPPLSNRRLRAPRWRRESSREVPPATLARSTAAILLPAAGLRPAGTMFLTLALLRKRIPGKQWIGKYRRPRVVTTTMKQAMIRRLEIEAENEYWLSRPYLTRQEECNHNREARVARWEAFKALKSSKFPEHRYMSDHLNHLNVSKKWTS", "length": 313, "header": "tr|A0A8V0XRM2-1|A0A1D5PPI7_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein L57 OS=Gallus gallus OX=9031 GN=MRPL57 PE=4 SV=1 CANONICAL=A0A1D5PPI7-1" }, "locus": { "chromosome": "1", "start_pos": 178474500, "end_pos": 178473216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012994.1", "url": "https://www.ensembl.org/id/ENSGALT00010012994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007556.1", "url": "https://www.ensembl.org/id/ENSGALP00010007556.1" } ] } }, { "isoform_ac": "A0A8V0XRN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRN1/entry", "sequence": { "sequence": "MRAPPPSLHYRENCARAPRHPGRLLRDKMAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDLKRPGYRHDVFNAGPTPEEDSWKAVDWKIQAAESSYHYHEAGDDPKAGN", "length": 172, "header": "tr|A0A8V0XRN1-1|A0A1D5PPI7_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein L57 OS=Gallus gallus OX=9031 GN=MRPL57 PE=4 SV=1 CANONICAL=A0A1D5PPI7-1" }, "locus": { "chromosome": "1", "start_pos": 178492328, "end_pos": 178473403, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012999.1", "url": "https://www.ensembl.org/id/ENSGALT00010012999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007561.1", "url": "https://www.ensembl.org/id/ENSGALP00010007561.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771615", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771615", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BP93-1", "protein_name": "Mitochondrial ribosomal protein L57", "gene_name": "MRPL57", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFLTALLRRNRIPGRQWIGKHRRPRPVSAQAKQNMIRRLETEAENQYWLSRPFLTAEQERGHAAVRRAAAFQALKAAQAARFPAHRRLEEQLGHLLVTRKWS", "length": 102 }, "evidence": [ { "id": "A0A1D5PPI7", "url": "https://omabrowser.org/oma/group/A0A1D5PPI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H8I1-1", "protein_name": "Ribosomal protein 63, mitochondrial", "gene_name": "Mrpl57", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFLTSALLRGRIPGRQWIGKHRRPRNVTFRMKENMLRRLEVEAENHYWLSMPYMTAEQEFGHAAERRAQAFEAIKAAATSKFPKHRYVADQLAHLNVTKKWS", "length": 102 }, "evidence": [ { "id": "A0A1D5PPI7", "url": "https://omabrowser.org/oma/group/A0A1D5PPI7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZC04-1", "protein_name": "Large ribosomal subunit protein mL63", "gene_name": "MRPL57", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFLTALLCRGRIPGRQWIGKHRRPRTVSALAKQNMIRRLEIEAENHYWLSRPFLTAEQERGHAAARRAAAFEALKAAQAAKFPAHRRLEDQLDHLNVTRKWS", "length": 102 }, "evidence": [ { "id": "A0A1D5PPI7", "url": "https://omabrowser.org/oma/group/A0A1D5PPI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BQC6-1", "protein_name": "Large ribosomal subunit protein mL63", "gene_name": "MRPL57", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLTALLWRGRIPGRQWIGKHRRPRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQERGHAAVRRREAFEAIKAAATSKFPPHRFIADQLDHLNVTKKWS", "length": 102 }, "evidence": [ { "id": "A0A1D5PPI7", "url": "https://omabrowser.org/oma/group/A0A1D5PPI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQF8-1", "protein_name": "Large ribosomal subunit protein mL63", "gene_name": "Mrpl57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLTAVLLRGRIPGRQWIGKHRRPRTVSFQAKESMIRRLEVEAENHYWLSMPYMTAEQECGHAAERRAQAFEAIKAAATSKFPKHRYIADQLDHLNISKKWS", "length": 102 }, "evidence": [ { "id": "A0A1D5PPI7", "url": "https://omabrowser.org/oma/group/A0A1D5PPI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPI7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPI7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPI7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PCW8-1", "uniprot_ac": "A0A1D5PCW8", "uniprot_id": "A0A1D5PCW8_CHICK", "mass": { "chemical_mass": 88018.0, "monoisotopic_mass": 88018.0 }, "refseq": { "ac": "NP_001026760", "name": "GRIP and coiled-coil domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026760" }, "gene_names": [ { "name": "GCC1", "type": "recommended", "evidence": [ { "id": "A0A1D5PCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" } ] }, { "name": "GCC1", "type": "synonym", "evidence": [ { "id": "NP_001026760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026760" } ] } ], "protein_names": [ { "name": "GRIP and coiled-coil domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8/entry#names_and_taxonomy" } ] }, { "name": "GRIP and coiled-coil domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026760" } ] }, { "name": "Golgi coiled-coil protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851395.1, SRR13267659.296415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000006.1. On Sep 20, 2021 this sequence version replaced NP_001026760.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026760" } ] }, { "annotation": "Probably involved in maintaining Golgi structure.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8#function" }, { "database": "UniProtKB", "id": "ARBA00055375", "url": "https://www.uniprot.org/uniprotkb/ARBA00055375#function" }, { "database": "UniProtKB", "id": "A0A8V0XS87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS87#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GCC1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8", "locus": { "chromosome": "1", "start_pos": 1011082, "end_pos": 1006145, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006300", "url": "https://www.ensembl.org/id/ENSGALG00010006300" } ] } } ], "crossref": [ { "id": "A0A1D5PCW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033149", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033149", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "430581", "url": "https://www.ncbi.nlm.nih.gov/gene/430581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430581", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430581", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AEMQAIN", "url": "https://omabrowser.org/oma/group/AEMQAIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PCW8", "url": "https://www.orthodb.org/?gene=A0A1D5PCW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XS87", "url": "https://www.orthodb.org/?gene=A0A8V0XS87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23157:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23157:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PCW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKFGMNFGGGPSKKELLETIESQKKQLLNYQARLKDVVIAYKSLINEKEALEASLKVLSASHEADVGLSGAQPACVAASSPSLADPADDKSSVHSEDSTGTATSADTTASLASAKGEQGAEDDKPAAAAASLKSEEANGSEGGGGASSGDVPCAAGEADRRVLQLKTQLATLTSALSTVTQEKSRMEASYQADKKKMKQDLDDAVKKAEDETDRLETELRSVQEQLAETKARLITQQHDRAQEQSDHAVMLRELQKLLQSERALRQDAELKLEETREVLAGRVCMADRAEGYELQIKQLSQEVEDLKRELQAVQEERKKPDPRVQDLQEEMANLKNHFQAQLLQEMRKTAQAEEQLRQHAQMEEQRVADLEGQVSEVSGLLGTYEKAKQKDQVVIQKLKDRIVQLDQENKTLAIAASSRSPADVNVEEGNLDVNVLKDKMEKLKKLLQAAAKKSQPTLDIEKLCELELPKGTEAGDGEKATALYYQQELKQLKEEFERYKMRAQVVLKNKSAKDGNLAKELEEAQEQLADLKEKYVVLQLSSEEVEKQHQLDMEAKRQEFCQLQQLHRQELERCQLEYRERALKLEEEMHKQRDRALAVLAEKDQELEQLRSVVLPYTGLQGSKNYMAPGTDTASSDPPANGSTEILPQALHLSTNAEPTFILYAEQLARKEVEIVALRKQKHKLEMQVHQLQEKVLVEEERHQEEVSALQSEIQKNFRDKSREGANLEYLKNIVYRFLTLPDSLGRQQTLTAILTILHFSPEEKQAVRKQSAHSSWWLSGKR", "length": 784, "header": "tr|A0A1D5PCW8-1|A0A1D5PCW8_CHICK Isoform 1 of GRIP and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GCC1 PE=1 SV=1 CANONICAL=A0A1D5PCW8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8/entry", "sequence": { "sequence": "MEKFGMNFGGGPSKKELLETIESQKKQLLNYQARLKDVVIAYKSLINEKEALEASLKVLSASHEADVGLSGAQPACVAASSPSLADPADDKSSVHSEDSTGTATSADTTASLASAKGEQGAEDDKPAAAAASLKSEEANGSEGGGGASSGDVPCAAGEADRRVLQLKTQLATLTSALSTVTQEKSRMEASYQADKKKMKQDLDDAVKKAEDETDRLETELRSVQEQLAETKARLITQQHDRAQEQSDHAVMLRELQKLLQSERALRQDAELKLEETREVLAGRVCMADRAEGYELQIKQLSQEVEDLKRELQAVQEERKKPDPRVQDLQEEMANLKNHFQAQLLQEMRKTAQAEEQLRQHAQMEEQRVADLEGQVSEVSGLLGTYEKAKQKDQVVIQKLKDRIVQLDQENKTLAIAASSRSPADVNVEEGNLDVNVLKDKMEKLKKLLQAAAKKSQPTLDIEKLCELELPKGTEAGDGEKATALYYQQELKQLKEEFERYKMRAQVVLKNKSAKDGNLAKELEEAQEQLADLKEKYVVLQLSSEEVEKQHQLDMEAKRQEFCQLQQLHRQELERCQLEYRERALKLEEEMHKQRDRALAVLAEKDQELEQLRSVVLPYTGLQGSKNYMAPGTDTASSDPPANGSTEILPQALHLSTNAEPTFILYAEQLARKEVEIVALRKQKHKLEMQVHQLQEKVLVEEERHQEEVSALQSEIQKNFRDKSREGANLEYLKNIVYRFLTLPDSLGRQQTLTAILTILHFSPEEKQAVRKQSAHSSWWLSGKR", "length": 784, "header": "tr|A0A1D5PCW8-1|A0A1D5PCW8_CHICK Isoform 1 of GRIP and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GCC1 PE=1 SV=1 CANONICAL=A0A1D5PCW8-1" }, "locus": { "chromosome": "1", "start_pos": 1010005, "end_pos": 1006388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015041.1", "url": "https://www.ensembl.org/id/ENSGALT00010015041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008843.1", "url": "https://www.ensembl.org/id/ENSGALP00010008843.1" } ] } }, { "isoform_ac": "A0A8V0XS87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS87/entry", "sequence": { "sequence": "MSAACRAPVRGAMEKFGMNFGGGPSKKELLETIESQKKQLLNYQARLKDVVIAYKSLINEKEALEASLKVLSASHEADVGLSGAQPACVAASSPSLADPADDKSSVHSEDSTGTATSADTTASLASAKGEQGAEDDKPAAAAASLKSEEANGSEGGGGASSGDVPCAAGEADRRVLQLKTQLATLTSALSTVTQEKSRMEASYQADKKKMKQDLDDAVKKAEDETDRLETELRSVQEQLAETKARLITQQHDRAQEQSDHAVMLRELQKLLQSERALRQDAELKLEETREVLAGRVCMADRAEGYELQIKQLSQEVEDLKRELQAVQEERKKPDPRVQDLQEEMANLKNHFQAQLLQEMRKTAQAEEQLRQHAQMEEQRVADLEGQVSEVSGLLGTYEKAKQKDQVVIQKLKDRIVQLDQENKTLAIAASSRSPADVNVEEGNLDVNVLKDKMEKLKKLLQAAAKKSQPTLDIEKLCELELPKGTEAGDGEKATALYYQQELKQLKEEFERYKMRAQVVLKNKSAKDGNLAKELEEAQEQLADLKEKYVVLQLSSEEVEKQHQLDMEAKRQEFCQLQQLHRQELERCQLEYRERALKLEEEMHKQRDRALAVLAEKDQELEQLRSVVLPYTGLQGSKNYMAPGTDTASSDPPANGSTEILPQALHLSTNAEPTFILYAEQLARKEVEIVALRKQKHKLEMQVHQLQEKVLVEEERHQEEVSALQSEIQKNFRDKSREGANLEYLKNIVYRFLTLPDSLGRQQTLTAILTILHFSPEEKQAVRKQSAHSSWWLSGKR", "length": 796, "header": "tr|A0A8V0XS87-1|A0A1D5PCW8_CHICK Computationally mapped isoform of GRIP and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GCC1 PE=1 SV=1 CANONICAL=A0A1D5PCW8-1" }, "locus": { "chromosome": "1", "start_pos": 1010005, "end_pos": 1006238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015031.1", "url": "https://www.ensembl.org/id/ENSGALT00010015031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008839.1", "url": "https://www.ensembl.org/id/ENSGALP00010008839.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430581", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287APX2-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "GCC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKFGMNFGGGPSKRDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQPQSLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPACGPPPPKSEEASGSESGVSSSSGDGPPGGGEVDKRVHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASKKLEEERGRLEGELKGLQEQVAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGQAYAAGQVEGFELQTKQLTREVEELKGELQALRDEKNRPDPRLQELQEEAACLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLTIQKLKERILQLDLENRTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKKLLQVAARKSQATLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKVRAQVVLKSKNTKDGNLGKELEEAQEQLAELKEKYISLRLSCEELERQHQQEAEGWKQELARLQHTHRQELERSQLDFRDRTLKLEEELHKQRDRALAVLAEKDLELEQLRSVALSSGLPGRRSPVGGSGPGDPADTSSPDSLTQALQLAAASEPTFFLYAEQLARKEVEITSLRKQRHRLEVEVHQLQDRLLEEGERHREEVGALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDALGRQQTLTAILTILHFSPEEKQVIMRLPAAGSWWPSGKR", "length": 775 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BBV8-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "gcc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKFGMSFGGGPSKKELLETIEVQKKQLVKYQTRFKDVVRAYQSLLKEKEALEASLKVLTISQEVDLSRVDNLSFGEASGSRALPSDLGDDRCSLHSEDSLDTAASAETATSVTSNSTKGDQIEDDQSCAVDGATAGAVVHTSPQQSEEASGSESGVSTSSSGCSEPTPQVADTDRRVIQLKTQLSTLTSSLATVTQEKSRMEASFQADKRKMKQELEELQARLEEDKKQHQAELQNLQEQFAESKARVITQQHEREQEQGDHALMLRELQKLLQEERGLRQDAELKLEDARATLAEAMQAADRGLDYESQLKEIIQERDELKKSLKAAAVENSKPDPRVEELQQENADLKAHFNQQLQQEIRKVAQADELLREQAKMEEIRVASLEERVSELSELLGACEKARQKDQQNTQRLRERILQLDTENKTLAMAAVNRTTSSDLNMDDMNLNVDALKDKLEKVKKLLLLAAQRSQDQSLDIEKLLEGGEKDHEVSESEKASALHYQQELRQIKEEFERYKMRAQGVLKNKNTKDGNQAKELEEARDQLAELKEKYINLRIQSDEAEVKHKRDLEERQQGLAALQQTHKQEVEKLEAQHRENFMRLEEELHKQRDRTMALLAEKDLELERLRASAVMGFGSHQRHIINSSAALEGGDLDEVDPEQEESDIIAQALKLAGPNEPTLLLYAEQLARKEVEVAALRKQKHRLEEDLHQLQGKLIANGERHEEELVELRGQLDKRIRDKGRDGANLEYLKNVIYKFLTLQDTRGRQQTLTAILTILHFSPQEKQVVLKQQQHSWWTAGMR", "length": 802 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZPA1-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "Gcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADAGLSGVQPPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSVKGEFGVEDDRVARGPLPPKSEEASGSESGVSSSSGDGPSAGSEIDKRVHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDANKKAEEERGRLEGDLKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAADQLEGFELQTKQLTREVEELKGELQAIREEKNRPDPRLQELQQEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKDRILQLDLENKTLALAASSRPSLDIHGDESSLDINVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDPDIMANSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKDKYISLRLSCEELENQHQQEAEDWKQELTRLQQLHQQELERSQLDFRDRTMKLEEELHKQRDRALAVLAEKDLELEQLRSVALSSGLPGRRSPVGGVGGGGLGDPDDPASSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEAHQLQERLLEEGERHREEVGALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVLMRLPSGGSWWPSGKR", "length": 778 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GZ80-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "Gcc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLASVQPPGLTLPDSVDDRCSTHSEDSTGTATSLDTAASLTSIKGEFGVEDDRMARGPLPLKSEEASGSESGVSSSSGDGPSAGSEMDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDANKKAEEERDRLVGELKGLQEQIAETKARLITQQHDRAQEQSDHAVMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAADQIEGFELQTKQLTREVEELKGELQAIQDEKNRPDPRLQELQQEAARLKSHFQAQLQQEMRKTALAEDQLRQQCQVEEQRVAALENQISEVSELLGTYEKAKQKDQLTIQKLKERILQLDLENKTLALAASSRSPLDSHGDESSLDINVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDPEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKNKNTKDGSLAKELEAAQEQLAELKEKYISLRLSCEELESQHQQEAEDWKQELARLQQLHRQELEHSQLDFRDRTLKLEEELHKQRDRALAVLAEKDLELEQLRSVALSSGLPGRRSPVGGVGGGGLGDPADTASSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEMEAHQLQEKLLEEGERHREEVGALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPSGGGWWPSGKR", "length": 778 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8S2T0-1", "protein_name": "Protein GRIP", "gene_name": "GRIP", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSEDKESDVVGEEEESHVIKEDKELNDASNETLTENGDQLLQMIAELRLENDFLRSQFEGLKDEVAQGRSLQKAEQVEADSAQLKQLQEQVASLSREIDVEKQTRVAAEQALEHLREAYSEADAKSQEYSSKFSQVEQKLDQEIKERDEKYADLDAKFTRLHKRAKQRIQEIQKEKDDLDARFREVNETAERASSQHSSMQQELERTRQQANEALKAMDAERQQLRSANNKLRDTIEELRGSLQPKENKIETLQQSLLDKDQILEDLKKQLQAVEERKQIAVTELSAKHQKNLEGLEAQVVDALSERDKAAETISSLQVLLAEKESKIAEMEAAATGEAARLRAAAETLKGELAHLKSENEKEKETWEASCDALKSKLEIAESNYLQAEIEVAKMRSQLGSEMSMQTQILSTKDAELKGAREEINRLQSEFSSYKIRAHALLQKKDMELAAAKDSEQIKSLEEALKEAEKEVYLVSAERDRAQQDLQSALASLEKELEERAGALKDASEQIKSLEVKLDSTVARNQAEKQAWEEDLRVLEETWRRRCEALTAQNEASPAEGIEKELENAKLRNKRMKEEHESVRELADRLIEEKDREISRLVDEMTNLRKSMESKPVWNKSPSQVHHYGNNNTESQQQDVSNLSTSAAEHQILILARQQAQREEELAQTQRHILALQEEIEELERENRLHSQQEAVLKTELREMERKQKREGVDMTYLKNVILKLLETGEVEALLPVVGMLLQFSPEEIQKCQQAYHSSTTAATTTEATPSPASEGSGLSVFSRFSFS", "length": 788 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96CN9-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "GCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQLPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPARGPPPPKSEEASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQLRSVALASGLPGRRSPVGGGGPGDPADTSSSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEVHQLQDRLLEEGERHREEVAALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPTSASWWPSGKR", "length": 775 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4H2-1", "protein_name": "GRIP and coiled-coil domain-containing protein 1", "gene_name": "Gcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLSGVQPPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSVKGEFGVEDDRAARGPLPPKSEEASGSESGVSSSSGDGPSAGSEMDKRVHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDANKKAEEERGRLEGDLKVLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAADQVEGFELQTKQLTREVEELKGELQTIRDEKNRPDPRLQELQQEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALESQISEVSELLGTYEKAKQKDQLAIQKLKERLLQLDLENKTLALAASSRSSLDIHGDESSLDINVLKDKMEKLKKLLQVAARKSQVTLDVEKLCDPEIMANSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGSLGKELEAAQEQLAELKDKYISLRLSCEELESQHQQEAEDWKQELARLQQLHRQELERSQLDFRDRTLKLEEELHKQRDRALAVLAEKDLELEQLRSVALSSGLPGRRSPVGGVGGGGLGDPADTASSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEAHQLQERLLEEGERHREEVGALQSHIEKNMRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVLMRLPSGGSWWPSGKR", "length": 778 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VGR1-1", "protein_name": "GRIP and coiled-coil domain containing 88 kDa", "gene_name": "GCC88", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKRQRELEALVSTQKEQLGRYEKRLKDVVTAYKGLLKEKEALETSLAAHAEATAVGESGSPARELESKKTSTDSADGATEGAAPGPPAPPAEGQLQTQIITLMNSLATLSAEKSRMEASFQADKKQLRSQIAQKEQTIQELNTRAKEQAARAKSDVDEIKAKWIVERQEREKETNNQMLMIRELQKLYADERHLKDNIEMQLNNFKTQFASNEAENSRLRELQSQLKEARSQLKQFQAKTEHSAAASASADSAALLQQVRLEMQQLKEQHAVAIRQEQRRVLRAEEQSRRQAALHEDRVASLEARLAELSTTVGSYDRLRQQDQDSIHDLKQQLQDLEQAHVRPTSNSRALNEDVDVATLVDEMVRLKKLLTTANARSANPLDLGEILSFSGQTATRVESHAHCEQQLQGVQQMLEASKQQRQLLEQKVQLQHSHIQTLQEKVQVLNRNIDEAEVELKQQGEKLRLALKNERTKWQEAKAELENETRCKLNELEQLLQKQRQRSLQLLDEKEQEIKTLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSSDTDSVEGEQRERKLKVRSKKMSMGENCHMLHYANELARKDIEITTLRKAKYAAESTLRKAIQDKVTSQQEMHEKIECLKEQVDRLERCKTREGANLEYLKNVIISYIVTRDADGKRHMLNAISAVLQFTAAEMQAINASFQKK", "length": 695 }, "evidence": [ { "id": "A0A1D5PCW8", "url": "https://omabrowser.org/oma/group/A0A1D5PCW8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCW8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PCW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW8" }, { "id": "PS50913", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRIP", "eco_id": "ECO_0000259", "start_pos": 722, "end_pos": 772, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 642, "end_pos": 644 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZ00-1", "uniprot_ac": "A0A1D5PZ00", "uniprot_id": "A0A1D5PZ00_CHICK", "mass": { "chemical_mass": 36777.0, "monoisotopic_mass": 36777.0 }, "refseq": { "ac": "XP_015138623", "name": "CYFIP-related Rac1 interactor B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138623" }, "gene_names": [ { "name": "FAM49B", "type": "recommended", "evidence": [ { "id": "A0A1D5PZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ] }, { "name": "FAM49B", "type": "synonym", "evidence": [ { "id": "XP_015138623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138623" } ] } ], "protein_names": [ { "name": "CYFIP related Rac1 interactor B", "type": "synonym", "evidence": [ { "id": "A0A1D5PZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00/entry#names_and_taxonomy" } ] }, { "name": "CYFIP-related Rac1 interactor B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138623" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM49B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00", "locus": {} } ], "crossref": [ { "id": "A0A1D5PZ00", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZ00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036490", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036490", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420330", "url": "https://www.ncbi.nlm.nih.gov/gene/420330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420330", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420330", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYRSRFN", "url": "https://omabrowser.org/oma/group/EYRSRFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZ00", "url": "https://www.orthodb.org/?gene=A0A1D5PZ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TTC4", "url": "https://www.orthodb.org/?gene=A0A3Q2TTC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSR7", "url": "https://www.orthodb.org/?gene=A0A8V0XSR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX05", "url": "https://www.orthodb.org/?gene=A0A8V0XX05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZ03", "url": "https://www.orthodb.org/?gene=A0A8V0XZ03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1H6", "url": "https://www.orthodb.org/?gene=A0A8V0Y1H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1I0", "url": "https://www.orthodb.org/?gene=A0A8V0Y1I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y596", "url": "https://www.orthodb.org/?gene=A0A8V0Y596", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5A7", "url": "https://www.orthodb.org/?gene=A0A8V0Y5A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTC4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y596", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y596", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y596-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y596-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 324, "header": "tr|A0A1D5PZ00-1|A0A1D5PZ00_CHICK Isoform 1 of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00/entry", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 324, "header": "tr|A0A1D5PZ00-1|A0A1D5PZ00_CHICK Isoform 1 of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139470774, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019686.1", "url": "https://www.ensembl.org/id/ENSGALT00010019686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011234.1", "url": "https://www.ensembl.org/id/ENSGALP00010011234.1" } ] } }, { "isoform_ac": "A0A3Q2TTC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTC4/entry", "sequence": { "sequence": "MGNLIKVLTRDIDHNAAHFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 324, "header": "tr|A0A3Q2TTC4-1|A0A3Q2TTC4_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139471882, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019700.1", "url": "https://www.ensembl.org/id/ENSGALT00010019700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011248.1", "url": "https://www.ensembl.org/id/ENSGALP00010011248.1" } ] } }, { "isoform_ac": "A0A8V0XSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSR7/entry", "sequence": { "sequence": "CAVTCWLPPLPPRSSPPVHPGHRTPARLAGPLWCFAARPLPLLPPPLSAGGSGAVAIRPCPARGPVRPGPAQGGGGSGSVRIAGRLDSEDKLLHRLSGEEEFSLKTARRYYQLSGGQEQSAALAVDAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 425, "header": "tr|A0A8V0XSR7-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139529078, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019703.1", "url": "https://www.ensembl.org/id/ENSGALT00010019703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011251.1", "url": "https://www.ensembl.org/id/ENSGALP00010011251.1" } ] } }, { "isoform_ac": "A0A8V0XX05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX05/entry", "sequence": { "sequence": "MPDGTPWSSSPPLQSTIFGLFLLIKENFLFSHSCLGRYLNMGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 364, "header": "tr|A0A8V0XX05-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139470894, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019681.1", "url": "https://www.ensembl.org/id/ENSGALT00010019681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011229.1", "url": "https://www.ensembl.org/id/ENSGALP00010011229.1" } ] } }, { "isoform_ac": "A0A8V0XZ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ03/entry", "sequence": { "sequence": "MVLPAGGRLSREQLQHAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 315, "header": "tr|A0A8V0XZ03-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139481342, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019705.1", "url": "https://www.ensembl.org/id/ENSGALT00010019705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011253.1", "url": "https://www.ensembl.org/id/ENSGALP00010011253.1" } ] } }, { "isoform_ac": "A0A8V0Y1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1H6/entry", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 322, "header": "tr|A0A8V0Y1H6-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139470774, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019690.1", "url": "https://www.ensembl.org/id/ENSGALT00010019690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011238.1", "url": "https://www.ensembl.org/id/ENSGALP00010011238.1" } ] } }, { "isoform_ac": "A0A8V0Y1I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I0/entry", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 321, "header": "tr|A0A8V0Y1I0-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139470774, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019696.1", "url": "https://www.ensembl.org/id/ENSGALT00010019696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011244.1", "url": "https://www.ensembl.org/id/ENSGALP00010011244.1" } ] } }, { "isoform_ac": "A0A8V0Y596-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y596/entry", "sequence": { "sequence": "MEFVLYFMFIVLCQRSYLSSVTLERYLNMGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 352, "header": "tr|A0A8V0Y596-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139482179, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019683.1", "url": "https://www.ensembl.org/id/ENSGALT00010019683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011231.1", "url": "https://www.ensembl.org/id/ENSGALP00010011231.1" } ] } }, { "isoform_ac": "A0A8V0Y5A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5A7/entry", "sequence": { "sequence": "MSWIKKPRCCWLWGFTRSFPPFLFRCMRMSVWQLLQILKTSCCIGYLGKRSSLLRLQEDTTNWYLNMGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPNDEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAGLRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 390, "header": "tr|A0A8V0Y5A7-1|A0A1D5PZ00_CHICK Computationally mapped isoform of CYFIP related Rac1 interactor B OS=Gallus gallus OX=9031 GN=FAM49B PE=1 SV=1 CANONICAL=A0A1D5PZ00-1" }, "locus": { "chromosome": "2", "start_pos": 139528271, "end_pos": 139455042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019694.1", "url": "https://www.ensembl.org/id/ENSGALT00010019694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011242.1", "url": "https://www.ensembl.org/id/ENSGALP00010011242.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420330", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420330", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXI6-1", "protein_name": "CYFIP related Rac1 interactor B", "gene_name": "Cyrib", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIRSMLQ", "length": 324 }, "evidence": [ { "id": "A0A1D5PZ00", "url": "https://omabrowser.org/oma/group/A0A1D5PZ00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8D0HXM4-1", "protein_name": "CYFIP related Rac1 interactor B", "gene_name": "CYRIB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 324 }, "evidence": [ { "id": "A0A1D5PZ00", "url": "https://omabrowser.org/oma/group/A0A1D5PZ00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q921M7-1", "protein_name": "CYFIP-related Rac1 interactor B", "gene_name": "Cyrib", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIRSMLQ", "length": 324 }, "evidence": [ { "id": "A0A1D5PZ00", "url": "https://omabrowser.org/oma/group/A0A1D5PZ00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUQ9-1", "protein_name": "CYFIP-related Rac1 interactor B", "gene_name": "CYRIB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ", "length": 324 }, "evidence": [ { "id": "A0A1D5PZ00", "url": "https://omabrowser.org/oma/group/A0A1D5PZ00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity", "id": "GO:0001916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001916", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "positive regulation of memory T cell activation", "id": "GO:2000568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000568", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "regulation of chemotaxis", "id": "GO:0050920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050920", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "regulation of establishment of cell polarity", "id": "GO:2000114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000114", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "cellular response to molecule of bacterial origin", "id": "GO:0071219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071219", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" }, { "name": "MHC class Ib protein binding, via antigen binding groove", "id": "GO:0023030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023030", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ00" }, { "id": "PF07159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CYRIA/CYRIB Rac1 binding", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 320, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PMT1-1", "uniprot_ac": "A0A1D5PMT1", "uniprot_id": "A0A1D5PMT1_CHICK", "mass": { "chemical_mass": 92893.0, "monoisotopic_mass": 92893.0 }, "refseq": { "ac": "XP_004949334", "name": "colorectal mutant cancer protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949334" }, "gene_names": [ { "name": "MCC", "type": "recommended", "evidence": [ { "id": "A0A1D5PMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ] }, { "name": "MCC", "type": "synonym", "evidence": [ { "id": "XP_004949334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949334" } ] } ], "protein_names": [ { "name": "MCC regulator of WNT signaling pathway", "type": "synonym", "evidence": [ { "id": "A0A1D5PMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1/entry#names_and_taxonomy" } ] }, { "name": "colorectal mutant cancer protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004949334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949334" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949334" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1", "locus": { "chromosome": "Z", "start_pos": 46618585, "end_pos": 46420664, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008259", "url": "https://www.ensembl.org/id/ENSGALG00010008259" } ] } } ], "crossref": [ { "id": "A0A1D5PMT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PMT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000208", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415603", "url": "https://www.ncbi.nlm.nih.gov/gene/415603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EESRGQC", "url": "https://omabrowser.org/oma/group/EESRGQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMT1", "url": "https://www.orthodb.org/?gene=A0A1D5PMT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSX3", "url": "https://www.orthodb.org/?gene=A0A8V0XSX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX77", "url": "https://www.orthodb.org/?gene=A0A8V0XX77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1N6", "url": "https://www.orthodb.org/?gene=A0A8V0Y1N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949334", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1N6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSGVALKYGNDSPAELSELHLAALASLKGDVVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQNSVSVPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLSEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAVREERDRLRRRVRELQTRLQSVQATGPSSPSRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSTVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSVGDQTGDENITQMLKRAHDCRKMAENAAKALLMKLDGSCGGAYAVTGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKLGKECSDGTATPLTLAELRPYNESELTAELTNALRREKKLKTRVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 825, "header": "tr|A0A1D5PMT1-1|A0A1D5PMT1_CHICK Isoform 1 of MCC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=MCC PE=4 SV=1 CANONICAL=A0A1D5PMT1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1/entry", "sequence": { "sequence": "MNSGVALKYGNDSPAELSELHLAALASLKGDVVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQNSVSVPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLSEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAVREERDRLRRRVRELQTRLQSVQATGPSSPSRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSTVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSVGDQTGDENITQMLKRAHDCRKMAENAAKALLMKLDGSCGGAYAVTGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKLGKECSDGTATPLTLAELRPYNESELTAELTNALRREKKLKTRVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 825, "header": "tr|A0A1D5PMT1-1|A0A1D5PMT1_CHICK Isoform 1 of MCC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=MCC PE=4 SV=1 CANONICAL=A0A1D5PMT1-1" }, "locus": { "chromosome": "Z", "start_pos": 46616568, "end_pos": 46471187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019761.1", "url": "https://www.ensembl.org/id/ENSGALT00010019761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011309.1", "url": "https://www.ensembl.org/id/ENSGALP00010011309.1" } ] } }, { "isoform_ac": "A0A8V0XSX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX3/entry", "sequence": { "sequence": "MMAAAAAAEVSSAASSSSDTSSTGEEERMRRLFQTCDGDGDGFISRNDLLMVCRQLNMEESVAEIMHQLGTDENGKISFQDFSQCRMQLVREIRKEEVELSVKSDDSCKKKKLRDRIASWPTSSNNSLGALSGARESWEYDSGARDLQSPDLQSHFTLQKILENGGSTVTKQAALQKLLAQASNYSNSFGGNYLELANTLHLAALASLKGDVVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQNSVSVPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLSEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAVREERDRLRRRVRELQTRLQSVQATGPSSPSRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSTVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSVGDQTGDENITQMLKRAHDCRKMAENAAKALLMKLDGSCGGAYAVTGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKLGKECSDGTATPLTLAELRPYNESELTAELTNALRREKKLKTRVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 1005, "header": "tr|A0A8V0XSX3-1|A0A1D5PMT1_CHICK Computationally mapped isoform of MCC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=MCC PE=4 SV=1 CANONICAL=A0A1D5PMT1-1" }, "locus": { "chromosome": "Z", "start_pos": 46616568, "end_pos": 46420727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019765.1", "url": "https://www.ensembl.org/id/ENSGALT00010019765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011313.1", "url": "https://www.ensembl.org/id/ENSGALP00010011313.1" } ] } }, { "isoform_ac": "A0A8V0XX77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX77/entry", "sequence": { "sequence": "MPAGYAELSSSMETLHLAALASLKGDVVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQNSVSVPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLSEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAVREERDRLRRRVRELQTRLQSVQATGPSSPSRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSTVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSVGDQTGDENITQMLKRAHDCRKMAENAAKALLMKLDGSCGGAYAVTGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKLGKECSDGTATPLTLAELRPYNESELTAELTNALRREKKLKTRVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 820, "header": "tr|A0A8V0XX77-1|A0A1D5PMT1_CHICK Computationally mapped isoform of MCC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=MCC PE=4 SV=1 CANONICAL=A0A1D5PMT1-1" }, "locus": { "chromosome": "Z", "start_pos": 46616568, "end_pos": 46537180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019754.1", "url": "https://www.ensembl.org/id/ENSGALT00010019754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011302.1", "url": "https://www.ensembl.org/id/ENSGALP00010011302.1" } ] } }, { "isoform_ac": "A0A8V0Y1N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1N6/entry", "sequence": { "sequence": "MRKQCVKLHLAALASLKGDVVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQNSVSVPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLSEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAVREERDRLRRRVRELQTRLQSVQATGPSSPSRLTSANRPVNPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSTVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSVGDQTGDENITQMLKRAHDCRKMAENAAKALLMKLDGSCGGAYAVTGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKLGKECSDGTATPLTLAELRPYNESELTAELTNALRREKKLKTRVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 813, "header": "tr|A0A8V0Y1N6-1|A0A1D5PMT1_CHICK Computationally mapped isoform of MCC regulator of WNT signaling pathway OS=Gallus gallus OX=9031 GN=MCC PE=4 SV=1 CANONICAL=A0A1D5PMT1-1" }, "locus": { "chromosome": "Z", "start_pos": 46616568, "end_pos": 46524290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019758.1", "url": "https://www.ensembl.org/id/ENSGALT00010019758.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011306.1", "url": "https://www.ensembl.org/id/ENSGALP00010011306.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6G7-1", "protein_name": "MCC regulator of WNT signaling pathway", "gene_name": "Mcc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRRAGSGLSAAVSSAGPAVPPWGGSAMAAASACSSNGSSSDTSSTDEEERLRRLFQTCDSDGDGFISWNDLLMVCRQVNMEESVAEIMSQLGTDENGKISFQDFTRCHTQLVREIRKEEVDLFMKSDKSGKKKLRERITSWPTRSDNSLGALSATRESWAYDSGARDLQSPDLQSQLPLQKLLEYGESSLPQQAVLHKLLTQSPNFGTSTGGSYLELASTLHLAALASLKGDIVELNKRLQQTERERDLLEKTLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQQEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLESVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLTEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTPANRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSVGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAETEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFTVAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSSGKEKPGKESADAASPALSLAELRTNSDSELATEFANAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEEHSRPHTNETSL", "length": 1031 }, "evidence": [ { "id": "A0A1D5PMT1", "url": "https://omabrowser.org/oma/group/A0A1D5PMT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PZA7-1", "protein_name": "Colorectal mutant cancer protein isoform X1", "gene_name": "mcc", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAAAVALEVEVSSDSSSSTAEEERLQRLFQTCDGDGDGFINRNDLLMVCRQLNMEDSVAEIMGQLGADERGKISFEDFTRCRMQLLTEIQKEEGQLSLRSSDSDKQKLRERIASWPTSSENSLGARESWEFDSGARDLQSPELQSPTQTHPHLHPHLHHHQQSSPLLQKLLEQPSVLEPSSGVQQLLCQPAFSRSGGYLELANTLHLAALASLKGDVLELNQRLLQTERERDALEKRLTTAQCEQSHLLREHEEVQERTTLCYEERITELHSIIAELNKKIDLLQGATIREEDEFSELRSDLSHSQQEVNEDERSVDQDPDQASLSLPENQSMLVTADMDNCSDLNSELQRVLTGLESVLCGRKKSTCSLSVAEVDRHIEQLTTASQHCDLAIKTVEEIEGALGHDFYPSLCEERVRWEKELAGLRDENESLTAMLCSKEEDLNRTKASLNAIREERDRLRRRVREMQTRLQSVQPGAPPSPGRLTPAGRPINPSTGELSTSSSSNDIPIAKVAERVKLSKTRSESLPTERSILGSEISSIGVSSNVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLLGKYESNSTALRLALQYSEQCIEAYELLLALAESEQGLVLGQFRAAGVSAVGEHAGEESISQLLKKAHDSRKTAENAAKDLLTRLDGSCGAAFAVTGCSAQPWESLSSNSHTSTTSSTASSCDTDFSKEDEQRLKDYVQQLKNDRAAVKLTMLDLESVHIEPLSPELRTRGGGDAQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSSREAQEQAYLVHIEHLKAELEEHQEQRHTALTSTSTCSSSSKDCGDSPSVSVCDLRNLSDGDLAAELTGALRREKKLKARVQELVSALERLTKSSEVRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLECQMMAMVERHDTQVRMLKQRITLLEEETCRPHTNETSL", "length": 1013 }, "evidence": [ { "id": "A0A1D5PMT1", "url": "https://omabrowser.org/oma/group/A0A1D5PMT1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3UW40-1", "protein_name": "Mutated in colorectal cancers", "gene_name": "Mcc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSGVAVKYGNDSSAELSELHLAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSIIAELNKKIDRLQGTTIREEDEYSELRSELSQSQQEVNEDSRSVDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLESVVCGRKKSSCSLSVADVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTPANRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRTRSLSSTSSSGKEKPGKECADAASPALSLAELRTNSDSELATEFANAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 828 }, "evidence": [ { "id": "A0A1D5PMT1", "url": "https://omabrowser.org/oma/group/A0A1D5PMT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P23508-1", "protein_name": "Colorectal mutant cancer protein", "gene_name": "MCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSTNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELAAEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL", "length": 829 }, "evidence": [ { "id": "A0A1D5PMT1", "url": "https://omabrowser.org/oma/group/A0A1D5PMT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VF73-1", "protein_name": "Harmonin-binding protein USHBP1 PDZ-binding domain-containing protein", "gene_name": "Dmel\\CG34404", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNDVQVARVAKIATDVPRRSGKQRDSSGFQGKHSGSAAGEDFEYVFGSISPRGGGPGGRHLVGSSDLDSPEHTQRDTTESDNNISSCSTLDIVNKVEQLSVQQLENRVRDLTQRLQQAERQLTESNTEREICHKRLEVVSQAHECRITEMHCVIAELSKKLRSKQDHVIMEEQEPDGSELSFQEGSVYNSELNLTNPDAECQTEPLEDFEGACSTTSVGNVAHKPPELSHKGQVEALQEEVLHLRARIALLQSEISTKDAAVVEEQTKVAFDCESEVNECGQRLNDLNVCTSLTSPQKRIPAVPKMAERVKLRCASKHESGEDPSQDTSLSNEQINLVEHLVSELKEQNLYMENFMEPLHLSKDLERLQRRVEQLEMRNTMLALTLDECKEHTEHLYLLCGKYESNAVALQLALNCSDRAIEAYDVMLALLESKLALLGEKSVAAEESRRSVEAVARHLLARLDSEKNVCENSLGPWQHNINLGPEDAPKTGRPWCADDDNRLRYHVSKLKGRRSNVQHTIVSLESPFSDIYERKRLALEKEHELRSADKKSPIDLETAVIMQEILELRDSNLQLKTKMEEAEQERQNANERVGILHEALKQLQANNRVSYSEAEHAALTEQQLVEALTRETELKGRIQTLLANVTASQKAFDEKYEQLHQNVRELQKSNHNLGQMLDHTKRKYQLRVRKLEQKIVDLRLDYEQGHNHVPETTL", "length": 715 }, "evidence": [ { "id": "A0A1D5PMT1", "url": "https://omabrowser.org/oma/group/A0A1D5PMT1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of epithelial cell migration", "id": "GO:0010633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010633", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMT1" }, { "id": "PF10506", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Harmonin-binding protein USHBP1 PDZ-binding", "eco_id": "ECO_0000259", "start_pos": 400, "end_pos": 463, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 711, "end_pos": 713 }, { "start_pos": 821, "end_pos": 823 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P8S6-1", "uniprot_ac": "A0A1D5P8S6", "uniprot_id": "A0A1D5P8S6_CHICK", "mass": { "chemical_mass": 11886.0, "monoisotopic_mass": 11886.0 }, "refseq": { "ac": "NP_001377781", "name": "cysteine-rich transmembrane module-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" }, "gene_names": [ { "name": "CYSTM1", "type": "recommended", "evidence": [ { "id": "A0A1D5P8S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6" } ] }, { "name": "C13H5orf32", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] }, { "name": "C5orf32", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] }, { "name": "CYSTM1", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] } ], "protein_names": [ { "name": "Cysteine-rich transmembrane module-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5P8S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6/entry#names_and_taxonomy" } ] }, { "name": "UPF0467 protein C5orf32", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] }, { "name": "cysteine-rich and transmembrane domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] }, { "name": "cysteine-rich transmembrane module-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] }, { "name": "putative nuclear protein ORF1-FL49", "type": "synonym", "evidence": [ { "id": "NP_001377781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU130398.1, HAEK01127629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992428, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000254.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001377781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377781" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYSTM1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6", "locus": { "chromosome": "13", "start_pos": 317579, "end_pos": 383732, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008850", "url": "https://www.ensembl.org/id/ENSGALG00010008850" } ] } } ], "crossref": [ { "id": "A0A1D5P8S6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8S6", "database": "AlphaFoldDB", 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"MNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 111, "header": "tr|A0A1D5P8S6-1|A0A1D5P8S6_CHICK Isoform 1 of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6/entry", "sequence": { "sequence": "MNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 111, "header": "tr|A0A1D5P8S6-1|A0A1D5P8S6_CHICK Isoform 1 of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "locus": { "chromosome": "13", "start_pos": 333221, "end_pos": 318495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021001.1", "url": "https://www.ensembl.org/id/ENSGALT00010021001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012060.1", "url": "https://www.ensembl.org/id/ENSGALP00010012060.1" } ] } }, { "isoform_ac": "A0A8V0XUY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUY9/entry", "sequence": { "sequence": "MGARMWPPVARTDSASQMNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 128, "header": "tr|A0A8V0XUY9-1|A0A1D5P8S6_CHICK Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "locus": { "chromosome": "13", "start_pos": 335426, "end_pos": 318495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020999.1", "url": "https://www.ensembl.org/id/ENSGALT00010020999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012058.1", "url": "https://www.ensembl.org/id/ENSGALP00010012058.1" } ] } }, { "isoform_ac": "A0A8V0XUZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUZ4/entry", "sequence": { "sequence": "MCSAACLPQYKWCPFNSMSLGFPDLLCKHRTDSASQMNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 147, "header": "tr|A0A8V0XUZ4-1|A0A1D5P8S6_CHICK Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "locus": { "chromosome": "13", "start_pos": 343364, "end_pos": 318495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021005.1", "url": "https://www.ensembl.org/id/ENSGALT00010021005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012063.1", "url": "https://www.ensembl.org/id/ENSGALP00010012063.1" } ] } }, { "isoform_ac": "A0A8V0XZD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD5/entry", "sequence": { "sequence": "MSNSGPLESSLKWSIYAGEKANQLFCLFSFFYRTDSASQMNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 150, "header": "tr|A0A8V0XZD5-1|A0A1D5P8S6_CHICK Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "locus": { "chromosome": "13", "start_pos": 333338, "end_pos": 318495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020997.1", "url": "https://www.ensembl.org/id/ENSGALT00010020997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012057.1", "url": "https://www.ensembl.org/id/ENSGALP00010012057.1" } ] } }, { "isoform_ac": "A0A8V0Y178-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y178/entry", "sequence": { "sequence": "MSLHFSHRIKQLLPVNIGLFLKPEALNIPLFIRTDSASQMNYENPPPYPGPGPTAPYPPYAPQPGGPPGPYPGYPPGPTGPYPPGQPGYQGYPQYGWQNAPPPPGPVYADGPKNTVYVVEERRRDDSGESACLTACWTALCCCCLWDMLT", "length": 150, "header": "tr|A0A8V0Y178-1|A0A1D5P8S6_CHICK Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Gallus gallus OX=9031 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0A1D5P8S6-1" }, "locus": { "chromosome": "13", "start_pos": 383690, "end_pos": 318495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021013.1", "url": "https://www.ensembl.org/id/ENSGALT00010021013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012065.1", "url": "https://www.ensembl.org/id/ENSGALP00010012065.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8S6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P8S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8S6" }, { "id": "PF12734", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12734" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cysteine-rich transmembrane", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 110, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 15, 40 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PIT2-1", "uniprot_ac": "A0A1D5PIT2", "uniprot_id": "A0A1D5PIT2_CHICK", "mass": { "chemical_mass": 21465.0, "monoisotopic_mass": 21465.0 }, "refseq": { "ac": "XP_418913", "name": "neurensin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418913" }, "gene_names": [ { "name": "NRSN1", "type": "recommended", "evidence": [ { "id": "A0A1D5PIT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ] }, { "name": "NRSN1", "type": "synonym", "evidence": [ { "id": "XP_418913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418913" } ] } ], "protein_names": [ { "name": "Neurensin 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PIT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2/entry#names_and_taxonomy" } ] }, { "name": "neurensin-1", "type": "synonym", "evidence": [ { "id": "XP_418913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418913.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418913" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRSN1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2", "locus": { "chromosome": "2", "start_pos": 57666400, "end_pos": 57673494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008072", "url": "https://www.ensembl.org/id/ENSGALG00010008072" } ] } } ], "crossref": [ { "id": "A0A1D5PIT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PIT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037811", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037811", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420822", "url": "https://www.ncbi.nlm.nih.gov/gene/420822", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420822", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420822", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASIWEHE", "url": "https://omabrowser.org/oma/group/ASIWEHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PIT2", "url": "https://www.orthodb.org/?gene=A0A1D5PIT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVS6", "url": "https://www.orthodb.org/?gene=A0A8V0XVS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14796:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14796:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSYADICGSKHAQGSTEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPSRWSSAFWKVGLVSGTAFMLIGLMVLVVGFLVPPKIEALGKDDFVVVDTRAIQFNGSLDICKLSGAILFCIGGTAMAACLLMAAFAKSYSKEEKYLQQRFKERIADIKTHANPVTKAPAPGESKIPVTLSKVQNVQPVSQT", "length": 195, "header": "tr|A0A1D5PIT2-1|A0A1D5PIT2_CHICK Isoform 1 of Neurensin 1 OS=Gallus gallus OX=9031 GN=NRSN1 PE=4 SV=1 CANONICAL=A0A1D5PIT2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2/entry", "sequence": { "sequence": "MSSYADICGSKHAQGSTEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPSRWSSAFWKVGLVSGTAFMLIGLMVLVVGFLVPPKIEALGKDDFVVVDTRAIQFNGSLDICKLSGAILFCIGGTAMAACLLMAAFAKSYSKEEKYLQQRFKERIADIKTHANPVTKAPAPGESKIPVTLSKVQNVQPVSQT", "length": 195, "header": "tr|A0A1D5PIT2-1|A0A1D5PIT2_CHICK Isoform 1 of Neurensin 1 OS=Gallus gallus OX=9031 GN=NRSN1 PE=4 SV=1 CANONICAL=A0A1D5PIT2-1" }, "locus": { "chromosome": "2", "start_pos": 57669288, "end_pos": 57667748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019247.1", "url": "https://www.ensembl.org/id/ENSGALT00010019247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010795.1", "url": "https://www.ensembl.org/id/ENSGALP00010010795.1" } ] } }, { "isoform_ac": "A0A8V0XVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVS6/entry", "sequence": { "sequence": "MCFLQAGRMSSYADICGSKHAQGSTEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPSRWSSAFWKVGLVSGTAFMLIGLMVLVVGFLVPPKIEALGKDDFVVVDTRAIQFNGSLDICKLSGAILFCIGGTAMAACLLMAAFAKSYSKEEKYLQQRFKERIADIKTHANPVTKAPAPGESKIPVTLSKVQNVQPVSQT", "length": 203, "header": "tr|A0A8V0XVS6-1|A0A1D5PIT2_CHICK Computationally mapped isoform of Neurensin 1 OS=Gallus gallus OX=9031 GN=NRSN1 PE=4 SV=1 CANONICAL=A0A1D5PIT2-1" }, "locus": { "chromosome": "2", "start_pos": 57671661, "end_pos": 57667748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019244.1", "url": "https://www.ensembl.org/id/ENSGALT00010019244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010792.1", "url": "https://www.ensembl.org/id/ENSGALP00010010792.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420822", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420822", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AW45-1", "protein_name": "Neurensin 1", "gene_name": "NRSN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVAGPETGRGHWELGRMSSCSNICGSKQAQAATESGYQRYGVRSYLHQFYEDCTTSIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEANFVVVDTHAVQFNGALDMCKLAGAVLFCIGGMSMAGCLLMSVFAKSYSKEEKILQQKFKERIADIKAHPQPITRAPGPGETKIPVTLSRVQNVQPVSAT", "length": 211 }, "evidence": [ { "id": "A0A1D5PIT2", "url": "https://omabrowser.org/oma/group/A0A1D5PIT2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IAE7-1", "protein_name": "Neurensin-1", "gene_name": "Nrsn1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSCSNTCGSKQTQADTEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVIFGLTVLAVGFLVPPKIEAFGEADFMVVDTHAVQFNGALDTCKLAGAVLFCIGGTSMAGCLLMSVFAKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGDTKIPVTLSRVQNVQPLSAT", "length": 195 }, "evidence": [ { "id": "A0A1D5PIT2", "url": "https://omabrowser.org/oma/group/A0A1D5PIT2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V892-1", "protein_name": "Neurensin 1", "gene_name": "Nrsn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSCSNTCGSRQAQADTEGGYQRRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVVLGLTVLAVGFLVPPKIEAFGEADFMVVDTHAVQYNGALDTCKLVGAVLFCIGGTSMAGCLLMSVFAKSYSKEEKFLQQKFKERIADIKAHTQPITKTPGPGDTKIPVTLSRVQNVQPLTAT", "length": 196 }, "evidence": [ { "id": "A0A1D5PIT2", "url": "https://omabrowser.org/oma/group/A0A1D5PIT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97799-1", "protein_name": "Neurensin-1", "gene_name": "Nrsn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSCSNTCGSRRAQADTEGGYQQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFMVVDTHAVKYNGALDTCKLAGAVLFCIGGTSMAGCLLMSVFAKSYSKEEKFLQQKFKERIADIKAHTQPITKAPGPGDTKIPVTLSRVQNVQPLSAT", "length": 196 }, "evidence": [ { "id": "A0A1D5PIT2", "url": "https://omabrowser.org/oma/group/A0A1D5PIT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZ57-1", "protein_name": "Neurensin-1", "gene_name": "NRSN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGAVLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIPVTLSRVQNVQPLLAT", "length": 195 }, "evidence": [ { "id": "A0A1D5PIT2", "url": "https://omabrowser.org/oma/group/A0A1D5PIT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PBZ2-1", "uniprot_ac": "A0A1D5PBZ2", "uniprot_id": "A0A1D5PBZ2_CHICK", "mass": { "chemical_mass": 38714.0, "monoisotopic_mass": 38714.0 }, "refseq": { "ac": "XP_001231272", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231272" }, "gene_names": [ { "name": "KHDRBS3", "type": "recommended", "evidence": [ { "id": "A0A1D5PBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ] }, { "name": "KHDRBS3", "type": "synonym", "evidence": [ { "id": "XP_001231272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231272" } ] } ], "protein_names": [ { "name": "KH RNA binding domain containing, signal transduction associated 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2/entry#names_and_taxonomy" } ] }, { "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_001231272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231272" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231272" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KHDRBS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2", "locus": { "chromosome": "2", "start_pos": 142122938, "end_pos": 142042185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008852", "url": "https://www.ensembl.org/id/ENSGALG00010008852" } ] } } ], "crossref": [ { "id": "A0A1D5PBZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031519", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420317", "url": "https://www.ncbi.nlm.nih.gov/gene/420317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420317", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYREQPY", "url": "https://omabrowser.org/oma/group/SYREQPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBZ2", "url": "https://www.orthodb.org/?gene=A0A1D5PBZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZD9", "url": "https://www.orthodb.org/?gene=A0A8V0XZD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7U1", "url": "https://www.orthodb.org/?gene=A0A8V0Y7U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11208:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11208:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDERYLPELMAEKDSLDPSFTHTLRLVNQEIEKYQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKTKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENAEVPVVRGKPSIRARGVPVPALTRGRGGVPPPPAGVPRGAPAPRGVPPSRGPVSRSRGLLAPRARGVPPPAGYRPLPPPPAQETYGEYEYDDGYGTAYDEQSYDSYDNSYSTQAQSGADYYDYGHGLSEETYESYGQEEWTNSRHKAPSARTTKGVYRDQPYARY", "length": 345, "header": "tr|A0A1D5PBZ2-1|A0A1D5PBZ2_CHICK Isoform 1 of KH RNA binding domain containing, signal transduction associated 3 OS=Gallus gallus OX=9031 GN=KHDRBS3 PE=3 SV=1 CANONICAL=A0A1D5PBZ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PBZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2/entry", "sequence": { "sequence": "MDERYLPELMAEKDSLDPSFTHTLRLVNQEIEKYQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKTKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENAEVPVVRGKPSIRARGVPVPALTRGRGGVPPPPAGVPRGAPAPRGVPPSRGPVSRSRGLLAPRARGVPPPAGYRPLPPPPAQETYGEYEYDDGYGTAYDEQSYDSYDNSYSTQAQSGADYYDYGHGLSEETYESYGQEEWTNSRHKAPSARTTKGVYRDQPYARY", "length": 345, "header": "tr|A0A1D5PBZ2-1|A0A1D5PBZ2_CHICK Isoform 1 of KH RNA binding domain containing, signal transduction associated 3 OS=Gallus gallus OX=9031 GN=KHDRBS3 PE=3 SV=1 CANONICAL=A0A1D5PBZ2-1" }, "locus": { "chromosome": "2", "start_pos": 142118816, "end_pos": 142042588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021016.1", "url": "https://www.ensembl.org/id/ENSGALT00010021016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012067.1", "url": "https://www.ensembl.org/id/ENSGALP00010012067.1" } ] } }, { "isoform_ac": "A0A8V0XZD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD9/entry", "sequence": { "sequence": "MDERYLPELMAEKDSLDPSFTHTLRLVNQEIEKYQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKTKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENAEVPVVRGKPSIRARGVPVPALTSRLCLGTSLLTPAPTSVKSNKQLVPCPEEAFYRLAKNKGRGGVPPPPAGVPRGAPAPRGVPPSRGPVSRSRGLLAPRARGVPPPAGYRPLPPPPAQETYGEYEYDDGYGTAYDEQSYDSYDNSYSTQAQRKKITRIVLNFYVGNSAPFYCF", "length": 354, "header": "tr|A0A8V0XZD9-1|A0A1D5PBZ2_CHICK Computationally mapped isoform of KH RNA binding domain containing, signal transduction associated 3 OS=Gallus gallus OX=9031 GN=KHDRBS3 PE=3 SV=1 CANONICAL=A0A1D5PBZ2-1" }, "locus": { "chromosome": "2", "start_pos": 142105363, "end_pos": 142042588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021004.1", "url": "https://www.ensembl.org/id/ENSGALT00010021004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012062.1", "url": "https://www.ensembl.org/id/ENSGALP00010012062.1" } ] } }, { "isoform_ac": "A0A8V0Y7U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7U1/entry", "sequence": { "sequence": "MDERYLPELMAEKDSLDPSFTHTLRLVNQEIEKYQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKTKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENAEVPVVRGKPSIRARGVPVPALTSRLCLGTSLLTPAPTSVKSNKQLVPCPEEAFYRLAKNKGRGGVPPPPAGVPRGAPAPRGVPPSRGPVSRSRGLLAPRARGVPPPAGYRPLPPPPAQETYGEYEYDDGYGTAYDEQSYDSYDNSYSTQAQSGADYYDYGHGLSEETYESYGQEEWTNSRHKAPSARTTKGVYRDQPYARY", "length": 382, "header": "tr|A0A8V0Y7U1-1|A0A1D5PBZ2_CHICK Computationally mapped isoform of KH RNA binding domain containing, signal transduction associated 3 OS=Gallus gallus OX=9031 GN=KHDRBS3 PE=3 SV=1 CANONICAL=A0A1D5PBZ2-1" }, "locus": { "chromosome": "2", "start_pos": 142118816, "end_pos": 142042588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021010.1", "url": "https://www.ensembl.org/id/ENSGALT00010021010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012064.1", "url": "https://www.ensembl.org/id/ENSGALP00010012064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420317", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420317", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O75525-1", "protein_name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "gene_name": "KHDRBS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 346 }, "evidence": [ { "id": "A0A1D5PBZ2", "url": "https://omabrowser.org/oma/group/A0A1D5PBZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JLP1-1", "protein_name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "gene_name": "Khdrbs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQSGADYYDYGHGLGEEAYDSYGQEDWTNSRHKAPSARTAKGVYREQPYGRY", "length": 346 }, "evidence": [ { "id": "A0A1D5PBZ2", "url": "https://omabrowser.org/oma/group/A0A1D5PBZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R226-1", "protein_name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "gene_name": "Khdrbs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEGKEEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSAADYYDYGHGLSEDAYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 346 }, "evidence": [ { "id": "A0A1D5PBZ2", "url": "https://omabrowser.org/oma/group/A0A1D5PBZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBZ2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBZ2" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 152, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P760-1", "uniprot_ac": "A0A1D5P760", "uniprot_id": "A0A1D5P760_CHICK", "mass": { "chemical_mass": 26965.0, "monoisotopic_mass": 26965.0 }, "refseq": { "ac": "XP_046756454", "name": "Kv channel-interacting protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756454" }, "gene_names": [ { "name": "KCNIP1", "type": "recommended", "evidence": [ { "id": "A0A1D5P760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760" } ] }, { "name": "KCNIP1", "type": "synonym", "evidence": [ { "id": "XP_046756454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756454" } ] } ], "protein_names": [ { "name": "Kv channel-interacting protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_046756454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756454" } ] }, { "name": "Potassium voltage-gated channel interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P760", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNIP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760", "locus": { "chromosome": "13", "start_pos": 3157723, "end_pos": 3453709, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010678", "url": "https://www.ensembl.org/id/ENSGALG00010010678" } ] } } ], "crossref": [ { "id": "A0A1D5P760", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P760", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002132", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002132", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416173", "url": "https://www.ncbi.nlm.nih.gov/gene/416173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YRGFKNX", "url": "https://omabrowser.org/oma/group/YRGFKNX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P760", "url": "https://www.orthodb.org/?gene=A0A1D5P760", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1C4", "url": "https://www.orthodb.org/?gene=A0A8V0Y1C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1D3", "url": "https://www.orthodb.org/?gene=A0A8V0Y1D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5Z0", "url": "https://www.orthodb.org/?gene=A0A8V0Y5Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5Z5", "url": "https://www.orthodb.org/?gene=A0A8V0Y5Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5Z9", "url": "https://www.orthodb.org/?gene=A0A8V0Y5Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7J7", "url": "https://www.orthodb.org/?gene=A0A8V0Y7J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9U0", "url": "https://www.orthodb.org/?gene=A0A8V0Y9U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9U5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH9", "url": "https://www.orthodb.org/?gene=A0A8V0YEH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5576894", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576894", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046756454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P760", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P760-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTEGESEGLQTLGIVVVLCSSLKLLHYLGLIDLSDDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 232, "header": "tr|A0A1D5P760-1|A0A1D5P760_CHICK Isoform 1 of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P760-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P760/entry", "sequence": { "sequence": "MWTEGESEGLQTLGIVVVLCSSLKLLHYLGLIDLSDDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 232, "header": "tr|A0A1D5P760-1|A0A1D5P760_CHICK Isoform 1 of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3197946, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025421.1", "url": "https://www.ensembl.org/id/ENSGALT00010025421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014368.1", "url": "https://www.ensembl.org/id/ENSGALP00010014368.1" } ] } }, { "isoform_ac": "A0A8V0Y1C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1C4/entry", "sequence": { "sequence": "MYLRAELLVRTYIKTSPKSPISDALCCLFLFKNKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNVDVCRISSELEGETRPNCTNSSSKEECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 253, "header": "tr|A0A8V0Y1C4-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3220170, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025428.1", "url": "https://www.ensembl.org/id/ENSGALT00010025428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014371.1", "url": "https://www.ensembl.org/id/ENSGALP00010014371.1" } ] } }, { "isoform_ac": "A0A8V0Y1D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D3/entry", "sequence": { "sequence": "MLASGSQLCFLASPISILQSNSSGTDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 221, "header": "tr|A0A8V0Y1D3-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3450392, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025456.1", "url": "https://www.ensembl.org/id/ENSGALT00010025456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014381.1", "url": "https://www.ensembl.org/id/ENSGALP00010014381.1" } ] } }, { "isoform_ac": "A0A8V0Y5Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z0/entry", "sequence": { "sequence": "MWTEGESEGLQTLGIVVVLCSSLKLLHYLGLIDLSDDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNVDVCRISSELEGETRPNCTNSSSKEECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 257, "header": "tr|A0A8V0Y5Z0-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3197946, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025425.1", "url": "https://www.ensembl.org/id/ENSGALT00010025425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014370.1", "url": "https://www.ensembl.org/id/ENSGALP00010014370.1" } ] } }, { "isoform_ac": "A0A8V0Y5Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z5/entry", "sequence": { "sequence": "MVAVGLNCSWGDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNVDVCRISSELEGETRPNCTNSSSKEECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 232, "header": "tr|A0A8V0Y5Z5-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3328609, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025442.1", "url": "https://www.ensembl.org/id/ENSGALT00010025442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014375.1", "url": "https://www.ensembl.org/id/ENSGALP00010014375.1" } ] } }, { "isoform_ac": "A0A8V0Y5Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Z9/entry", "sequence": { "sequence": "MNEKIRDACPSHPKHKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 210, "header": "tr|A0A8V0Y5Z9-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3414652, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025455.1", "url": "https://www.ensembl.org/id/ENSGALT00010025455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014380.1", "url": "https://www.ensembl.org/id/ENSGALP00010014380.1" } ] } }, { "isoform_ac": "A0A8V0Y7J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7J7/entry", "sequence": { "sequence": "MLLKVGARDYKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 205, "header": "tr|A0A8V0Y7J7-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3190082, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025436.1", "url": "https://www.ensembl.org/id/ENSGALT00010025436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014373.1", "url": "https://www.ensembl.org/id/ENSGALP00010014373.1" } ] } }, { "isoform_ac": "A0A8V0Y9U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U0/entry", "sequence": { "sequence": "MEHSLNVTAQQLTGSEGDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 213, "header": "tr|A0A8V0Y9U0-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3309191, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025441.1", "url": "https://www.ensembl.org/id/ENSGALT00010025441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014374.1", "url": "https://www.ensembl.org/id/ENSGALP00010014374.1" } ] } }, { "isoform_ac": "A0A8V0Y9U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U5/entry", "sequence": { "sequence": "MGAVMGTFSSLQTKQRRPSKDPARWFYVYQRDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNVDVCRISSELEGETRPNCTNSSSKEECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 252, "header": "tr|A0A8V0Y9U5-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3340125, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025450.1", "url": "https://www.ensembl.org/id/ENSGALT00010025450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014379.1", "url": "https://www.ensembl.org/id/ENSGALP00010014379.1" } ] } }, { "isoform_ac": "A0A8V0YEH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH9/entry", "sequence": { "sequence": "MSGCSKRCKHGIVKFAQTIFKLITGTLSKDKIEDELEMTTVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNVDVCRISSELEGETRPNCTNSSSKEECPSGVVNEETFKQIYAQFFPHGDASMYAHYLFNAFDTAQNGSVKFEDFVMALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDAPRQHVEVFFQKMDKNKDGVVTLDEFIESCQEDDNIMRSLQLFENVM", "length": 250, "header": "tr|A0A8V0YEH9-1|A0A1D5P760_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 1 OS=Gallus gallus OX=9031 GN=KCNIP1 PE=3 SV=1 CANONICAL=A0A1D5P760-1" }, "locus": { "chromosome": "13", "start_pos": 3453510, "end_pos": 3161376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025457.1", "url": "https://www.ensembl.org/id/ENSGALT00010025457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014382.1", "url": "https://www.ensembl.org/id/ENSGALP00010014382.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5576894", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576894", "resource": "Reactome", "description": "Phase 1 - inactivation of fast Na+ channels" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R426-1", "protein_name": "A-type potassium channel modulatory protein KCNIP1", "gene_name": "Kcnip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAVMGTFSSLQTKQRRPSKDIAWWYYQYQRDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM", "length": 227 }, "evidence": [ { "id": "A0A1D5P760", "url": "https://omabrowser.org/oma/group/A0A1D5P760/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JJ57-1", "protein_name": "A-type potassium channel modulatory protein KCNIP1", "gene_name": "Kcnip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640890" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRA5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD46", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRA5", "locus": { "chromosome": "2", "start_pos": 128135036, "end_pos": 128155417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011401", "url": "https://www.ensembl.org/id/ENSGALG00010011401" } ] } } ], "crossref": [ { "id": "A0A1D5PRA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRA5", "database": 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46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRA5/entry", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228, "header": "tr|A0A1D5PRA5-1|A0A1D5PRA5_CHICK Isoform 1 of Ankyrin repeat domain 46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "locus": { "chromosome": "2", "start_pos": 128142344, "end_pos": 128136843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027274.1", "url": "https://www.ensembl.org/id/ENSGALT00010027274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015531.1", "url": "https://www.ensembl.org/id/ENSGALP00010015531.1" } ] } }, { "isoform_ac": "A0A8V0Y4I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4I1/entry", "sequence": { "sequence": "GGRCRAGAGAATPAGVGGTALPCCPALLSCGGAGGKAEGVSSFLNTYGLEVLICSPGAVTPSRPQSELLVALLRIQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 286, "header": "tr|A0A8V0Y4I1-1|A0A1D5PRA5_CHICK Computationally mapped isoform of Ankyrin repeat domain 46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "locus": { "chromosome": "2", "start_pos": 128150954, "end_pos": 128136843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027267.1", "url": "https://www.ensembl.org/id/ENSGALT00010027267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015526.1", "url": "https://www.ensembl.org/id/ENSGALP00010015526.1" } ] } }, { "isoform_ac": "A0A8V0Y978-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y978/entry", "sequence": { "sequence": "PPPPLCSPVRAEERPEPRSSFLNTYGLEVLICSPGAVTPSRPQSELLVALLRIQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 264, "header": "tr|A0A8V0Y978-1|A0A1D5PRA5_CHICK Computationally mapped isoform of Ankyrin repeat domain 46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "locus": { "chromosome": "2", "start_pos": 128151223, "end_pos": 128136843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027272.1", "url": "https://www.ensembl.org/id/ENSGALT00010027272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015530.1", "url": "https://www.ensembl.org/id/ENSGALP00010015530.1" } ] } }, { "isoform_ac": "A0A8V0YAQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ7/entry", "sequence": { "sequence": "MNTWPFIFARGVQREVCTSGFSTCICLGLVLPEAGYLFRGLPSTPDTVRTMSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 278, "header": "tr|A0A8V0YAQ7-1|A0A1D5PRA5_CHICK Computationally mapped isoform of Ankyrin repeat domain 46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "locus": { "chromosome": "2", "start_pos": 128149009, "end_pos": 128136843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027263.1", "url": "https://www.ensembl.org/id/ENSGALT00010027263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015523.1", "url": "https://www.ensembl.org/id/ENSGALP00010015523.1" } ] } }, { "isoform_ac": "A0A8V0YAR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR5/entry", "sequence": { "sequence": "ASLLPCARRGAAGAAQVACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 227, "header": "tr|A0A8V0YAR5-1|A0A1D5PRA5_CHICK Computationally mapped isoform of Ankyrin repeat domain 46 OS=Gallus gallus OX=9031 GN=ANKRD46 PE=1 SV=1 CANONICAL=A0A1D5PRA5-1" }, "locus": { "chromosome": "2", "start_pos": 128151215, "end_pos": 128136843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027270.1", "url": "https://www.ensembl.org/id/ENSGALT00010027270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015528.1", "url": "https://www.ensembl.org/id/ENSGALP00010015528.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426304", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z556-1", "protein_name": "Ankyrin repeat domain 46", "gene_name": "ANKRD46", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3SX00-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "ANKRD46", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6TNT2-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "ankrd46", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYVFINDSSQTSVPLLQACIDGDLSFARRLLETGCDPNIRDHRGRTGLHLAAARGNVDICRFLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHNGSTPLVLAKRRGVNKDAIRLLEGLEEQEVKGFNRGAHSKLEAMQMAESESAMESHSLLNPNLQNSEGVLSSFRSTWQEFVEDLGFWRVLLLLVVIALLSLGIAYYVSGVLPFSASQLELVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q76K24-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "Ankrd46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPGLVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86W74-2", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "ANKRD46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTZ5-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "Ankrd46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPELVH", "length": 228 }, "evidence": [ { "id": "A0A1D5PRA5", "url": "https://omabrowser.org/oma/group/A0A1D5PRA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PGV4-1", "uniprot_ac": "A0A1D5PGV4", "uniprot_id": "A0A1D5PGV4_CHICK", "mass": { "chemical_mass": 13372.0, "monoisotopic_mass": 13372.0 }, "refseq": { "ac": "XP_418969", "name": "proteasome assembly chaperone 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418969" }, "gene_names": [ { "name": "PSMG4", "type": "recommended", "evidence": [ { "id": "A0A1D5PGV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4" } ] }, { "name": "PSMG4", "type": "synonym", "evidence": [ { "id": "XP_418969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418969" } ] } ], "protein_names": [ { "name": "Proteasome assembly chaperone 4", "type": "synonym", "evidence": [ { "id": "A0A1D5PGV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4/entry#names_and_taxonomy" } ] }, { "name": "proteasome assembly chaperone 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_418969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418969" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418969" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4", "locus": { "chromosome": "2", "start_pos": 66003520, "end_pos": 66008793, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011365", "url": "https://www.ensembl.org/id/ENSGALG00010011365" } ] } } ], "crossref": [ { "id": "A0A1D5PGV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PGV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042232", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042232", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420882", "url": "https://www.ncbi.nlm.nih.gov/gene/420882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGV4", "url": "https://www.orthodb.org/?gene=A0A1D5PGV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAK8", "url": "https://www.orthodb.org/?gene=A0A8V0YAK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33559:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33559:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9907900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418969", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PGV4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAGGGAAPDCIGLHDFSGQLGEQRVHFHAMRLQDSLFLWVGAAPALSSLAVAMCNPRDSVPVSTSLLGDPSDTASACLAQRLAKKTKKQVFVSYNLPNTDSSFTLLIENRIKEEMMAFPEKF", "length": 124, "header": "tr|A0A1D5PGV4-1|A0A1D5PGV4_CHICK Isoform 1 of Proteasome assembly chaperone 4 OS=Gallus gallus OX=9031 GN=PSMG4 PE=4 SV=1 CANONICAL=A0A1D5PGV4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4/entry", "sequence": { "sequence": "MEAAGGGAAPDCIGLHDFSGQLGEQRVHFHAMRLQDSLFLWVGAAPALSSLAVAMCNPRDSVPVSTSLLGDPSDTASACLAQRLAKKTKKQVFVSYNLPNTDSSFTLLIENRIKEEMMAFPEKF", "length": 124, "header": "tr|A0A1D5PGV4-1|A0A1D5PGV4_CHICK Isoform 1 of Proteasome assembly chaperone 4 OS=Gallus gallus OX=9031 GN=PSMG4 PE=4 SV=1 CANONICAL=A0A1D5PGV4-1" }, "locus": { "chromosome": "2", "start_pos": 66008696, "end_pos": 66003958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027175.1", "url": "https://www.ensembl.org/id/ENSGALT00010027175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015471.1", "url": "https://www.ensembl.org/id/ENSGALP00010015471.1" } ] } }, { "isoform_ac": "A0A8V0YAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK8/entry", "sequence": { "sequence": "MEAAGGGAAPDCIGLHDFSGQLGEQRVHFHAMRLQDSLFLWVGAAPALSSLAVAMCNPRDSVPVSTSLLGDPSDTASACLAQRLVSVMQFELRLLFHSTTSRREVVMRRGLASSPRQQTGPEETATSCARGCSAKKTKKQVFVSYNLPNTDSSFTLLIENRIKEEMMAFPEKF", "length": 173, "header": "tr|A0A8V0YAK8-1|A0A1D5PGV4_CHICK Computationally mapped isoform of Proteasome assembly chaperone 4 OS=Gallus gallus OX=9031 GN=PSMG4 PE=4 SV=1 CANONICAL=A0A1D5PGV4-1" }, "locus": { "chromosome": "2", "start_pos": 66008696, "end_pos": 66003958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027180.1", "url": "https://www.ensembl.org/id/ENSGALT00010027180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015474.1", "url": "https://www.ensembl.org/id/ENSGALP00010015474.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome assembly", "id": "GO:0043248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043248", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGV4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUD1-1", "uniprot_ac": "A0A1D5PUD1", "uniprot_id": "A0A1D5PUD1_CHICK", "mass": { "chemical_mass": 183033.0, "monoisotopic_mass": 183033.0 }, "refseq": { "ac": "XP_025003876", "name": "maestro heat-like repeat-containing protein family member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003876" }, "gene_names": [ { "name": "LOC101749352", "type": "recommended", "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ] }, { "name": "LOC101749352", "type": "synonym", "evidence": [ { "id": "XP_025003876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003876" } ] } ], "protein_names": [ { "name": "Maestro heat like repeat family member 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1/entry#names_and_taxonomy" } ] }, { "name": "maestro heat-like repeat-containing protein family member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025003876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003876" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101749352", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000029867", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101749352", "url": "https://www.ncbi.nlm.nih.gov/gene/101749352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749352", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749352", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVYIKAM", "url": "https://omabrowser.org/oma/group/EVYIKAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUD1", "url": "https://www.orthodb.org/?gene=A0A1D5PUD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAY2", "url": "https://www.orthodb.org/?gene=A0A8V0YAY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025003876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEARTRRLATTLMDATTDKEPLVQEQIYNALCYLGEAEPEEILHCCDEYLRQHDKLAYPHRVIILKAMETVVKNNISSLDKSTAKVVIFLASNEMTKSKEVVWEWQQAASNVLVAVGQRFINKVMEEVLTKFQPGILPHYFVMQTFSNLAVSNVFGMVPFLNSILGTMLPMLGMAKQDHMKSVFCYALQHFSESIQEYVANLDQAPDPTVRKDTFCNEIFSAYEVLFNSWLQHREPKLRLAVVEALGAMSYLMPGEKLEEQLPKLIPAVLSLYKKHTETFYISKSLCQILEASVDIGSRSLDVQLDALMGTLHPQICAPSDPAVPLTIKNHTEVLRCFTVLACSFPDRVLTFLLPKLESSSERTRVGTLLIMRQIINSAPSQMEIKKPFILSSMKLPLQDSNNKVRRAVVQVISAMAHHGYLEQPGGEAMLEFLVRQCALPSDAPQKQLPDADDPTSDSVRSISVNTLLLLSTTVDRMNNVLWPYLLEFVTPVQFTNALTPICKSLMHLSVKKREEGGNTSLIPYDLNGNLPSPHALTTRLLVVSSRPYTGDGRGAAALRLLHALCCSVHPALEQLWSKRVPLLVERIEENTEKSLHPEEWEEELLLLLQETLAAISDNAWICHFVTEMCRQLNGYNGFPAEKNFLYKCIGTTLGACVSKELVQKQLQELLETARYNEEAEWEGLASCFGMCAINHLEETLAKLEDFVRSDVFKKSVGLFSIFKDRSDHEVEKIKSALILCYGFVAAHAPRELLLSRVEADILRNISQYFSTKVLGIKVETKDLTLKLCLIRSVAMVSRAVRGSTKCTDFALGRKAELVAQMVEFIKAEPLDSMRTPVRQWAMVTCTHLVLLEPQLNDPDRTELTDACLAGVLALPPLDPLCDRDGDGGDAPYSEELFADTFGALQELLRTLLQRSLTPHGLQDMFAHLGPWIKSSKQHERQRAVELSAALLDFYLGRLNVSTVVPFYNLGVLIALFSPRCSDSVGSVRQRAVDCVYSLLYIQLCYEGFARDHRDEMVEGLKALKRGLEEPDFTVLFRTCTNIAMVIGKRVPPDQLMSLLLAMFEGLADPDKNCSRAATVMINALLKERGAVLQDKVPDIMSIIHSKLQEVDEEHVRKAAQQTVYILAAQHTGVVVSSLLGSTLPFDSHTCAMWRALAAEPGLTAQILEQLLEKVTGDVPYKESRAFLLGGSSERVATPLPMAATCALHEIMSAPESGPAVLGLYAPLFVTLLLRVSCTVGVQLPKSLQGRERKSSSSSNAATSRSLQPCSCAVQTLRAMLARGGSEAVAAAVGSAGGWELMENPERHHEGIAVLAGSMARHAGPRLPLIVKSLIPTLSSAFDSQRVTATAFLAELLSSNVVNDLMLLEGVMDSMTGRQKDPCLLVRVLALRGLGNIAVGAPEKVHKHGAKLLASMVNGMDDRDDPNNLVALEAMTSLSKLLEHLEERDVQAMLLHIAIRIRPFFDSEQPDLRRSSIVLFGNLTKFSEGDCEAFFEQILNGLVTLLLHLQDPKPEVVRACKFALRMCGPNMGCEGLCDMFLNHLREDRSLHYGEFMNNVCKHLMQSYPEMLNRLVLTNLFYFKSTWVDIRAAAPMFIGFLVLHVGEDHCHQVDLEQLISALNLLLKDPVPAVRMKVAETLGRLVRIL", "length": 1647, "header": "tr|A0A1D5PUD1-1|A0A1D5PUD1_CHICK Isoform 1 of Maestro heat like repeat family member 1 OS=Gallus gallus OX=9031 GN=LOC101749352 PE=1 SV=2 CANONICAL=A0A1D5PUD1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1/entry", "sequence": { "sequence": "MEARTRRLATTLMDATTDKEPLVQEQIYNALCYLGEAEPEEILHCCDEYLRQHDKLAYPHRVIILKAMETVVKNNISSLDKSTAKVVIFLASNEMTKSKEVVWEWQQAASNVLVAVGQRFINKVMEEVLTKFQPGILPHYFVMQTFSNLAVSNVFGMVPFLNSILGTMLPMLGMAKQDHMKSVFCYALQHFSESIQEYVANLDQAPDPTVRKDTFCNEIFSAYEVLFNSWLQHREPKLRLAVVEALGAMSYLMPGEKLEEQLPKLIPAVLSLYKKHTETFYISKSLCQILEASVDIGSRSLDVQLDALMGTLHPQICAPSDPAVPLTIKNHTEVLRCFTVLACSFPDRVLTFLLPKLESSSERTRVGTLLIMRQIINSAPSQMEIKKPFILSSMKLPLQDSNNKVRRAVVQVISAMAHHGYLEQPGGEAMLEFLVRQCALPSDAPQKQLPDADDPTSDSVRSISVNTLLLLSTTVDRMNNVLWPYLLEFVTPVQFTNALTPICKSLMHLSVKKREEGGNTSLIPYDLNGNLPSPHALTTRLLVVSSRPYTGDGRGAAALRLLHALCCSVHPALEQLWSKRVPLLVERIEENTEKSLHPEEWEEELLLLLQETLAAISDNAWICHFVTEMCRQLNGYNGFPAEKNFLYKCIGTTLGACVSKELVQKQLQELLETARYNEEAEWEGLASCFGMCAINHLEETLAKLEDFVRSDVFKKSVGLFSIFKDRSDHEVEKIKSALILCYGFVAAHAPRELLLSRVEADILRNISQYFSTKVLGIKVETKDLTLKLCLIRSVAMVSRAVRGSTKCTDFALGRKAELVAQMVEFIKAEPLDSMRTPVRQWAMVTCTHLVLLEPQLNDPDRTELTDACLAGVLALPPLDPLCDRDGDGGDAPYSEELFADTFGALQELLRTLLQRSLTPHGLQDMFAHLGPWIKSSKQHERQRAVELSAALLDFYLGRLNVSTVVPFYNLGVLIALFSPRCSDSVGSVRQRAVDCVYSLLYIQLCYEGFARDHRDEMVEGLKALKRGLEEPDFTVLFRTCTNIAMVIGKRVPPDQLMSLLLAMFEGLADPDKNCSRAATVMINALLKERGAVLQDKVPDIMSIIHSKLQEVDEEHVRKAAQQTVYILAAQHTGVVVSSLLGSTLPFDSHTCAMWRALAAEPGLTAQILEQLLEKVTGDVPYKESRAFLLGGSSERVATPLPMAATCALHEIMSAPESGPAVLGLYAPLFVTLLLRVSCTVGVQLPKSLQGRERKSSSSSNAATSRSLQPCSCAVQTLRAMLARGGSEAVAAAVGSAGGWELMENPERHHEGIAVLAGSMARHAGPRLPLIVKSLIPTLSSAFDSQRVTATAFLAELLSSNVVNDLMLLEGVMDSMTGRQKDPCLLVRVLALRGLGNIAVGAPEKVHKHGAKLLASMVNGMDDRDDPNNLVALEAMTSLSKLLEHLEERDVQAMLLHIAIRIRPFFDSEQPDLRRSSIVLFGNLTKFSEGDCEAFFEQILNGLVTLLLHLQDPKPEVVRACKFALRMCGPNMGCEGLCDMFLNHLREDRSLHYGEFMNNVCKHLMQSYPEMLNRLVLTNLFYFKSTWVDIRAAAPMFIGFLVLHVGEDHCHQVDLEQLISALNLLLKDPVPAVRMKVAETLGRLVRIL", "length": 1647, "header": "tr|A0A1D5PUD1-1|A0A1D5PUD1_CHICK Isoform 1 of Maestro heat like repeat family member 1 OS=Gallus gallus OX=9031 GN=LOC101749352 PE=1 SV=2 CANONICAL=A0A1D5PUD1-1" }, "locus": { "chromosome": "2", "start_pos": 148536021, "end_pos": 148439101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022666.1", "url": "https://www.ensembl.org/id/ENSGALT00010022666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013082.1", "url": "https://www.ensembl.org/id/ENSGALP00010013082.1" } ] } }, { "isoform_ac": "A0A8V0YAY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAY2/entry", "sequence": { "sequence": "MEGGTCVRAHAQIGCRHAGGAGPQKGAGLGNGSGGVDTRKGRGQNPGKGRGLRKGRGQDPEAAVPQERAGPKPGRGGAKTRKRPCLRKGRDRNPEGAGPRPGSGAGSGEGRVPGAPPPPFSADGGDPRNPATPGAVRGKPGTIGTAGAQRWASPGLGGLRTRSIMEARTRRLATTLMDATTDKEPLVQEQIYNALCYLGEAEPEEILHCCDEYLRQHDKLAYPHRVIILKAMETVVKNNISSLDKSTAKVVIFLASNEMTKSKEVVWEWQQAASNVLVAVGQRFINKVMEEVLTKFQPGILPHYFVMQTFSNLAVSNVFGMVPFLNSILGTMLPMLGMAKQDHMKSVFCYALQHFSESIQEYVANLDQAPDPTVRKDTFCNEIFSAYEVLFNSWLQHREPKLRLAVVEALGAMSYLMPGEKLEEQLPKLIPAVLSLYKKHTETFYISKSLCQILEASVDIGSRSLDVQLDALMGTLHPQICAPSDPAVPLTIKNHTEVLRCFTVLACSFPDRVLTFLLPKLESSSERTRVGTLLIMRQIINSAPSQMEIKKPFILSSMKLPLQDSNNKVRRAVVQVISAMAHHGYLEQPGGEAMLEFLVRQCALPSDAPQKQLPDADDPTSDSVRSISVNTLLLLSTTVDRMNNVLWPYLLEFVTPVQFTNALTPICKSLMHLSVKKREEGGNTSLIPYDLNGNLPSPHALTTRLLVVSSRPYTGDGRGAAALRLLHALCCSVHPALEQLWSKRVPLLVERIEENTEKSLHPEEWEEELLLLLQETLAAISDNAWICHFVTEMCRQLNGYNGFPAEKNFLYKCIGTTLGACVSKELVQKQLQELLETARYNEEAEWEGLASCFGMCAINHLEETLAKLEDFVRSDVFKKSVGLFSIFKDRSDHEVEKIKSALILCYGFVAAHAPRELLLSRVEADILRNISQYFSTKDLTLKLCLIRSVAMVSRAVRGSTKCTDFALGRKAELVAQMVEFIKAEPLDSMRTPVRQWAMVTCTHLVLLEPQLNDPDRTELTDACLAGVLALPPLDPLCDRDGDGGDAPYSEELFADTFGALQELLRTLLQRSLTPHGLQDMFAHLGPWIKSSKQHERQRAVELSAALLDFYLGRLNVSTVVPFYNLGVLIALFSPRCSDSVGSVRQRAVDCVYSLLYIQLCYEGFARDHRDEMVEGLKALKRGLEEPDFTVLFRTCTNIAMVIGKRVPPDQLMSLLLAMFEGLADPDKNCSRAATVMINALLKERGAVLQDKVPDIMSIIHSKLQEVDEEHVRKAAQQTVYILAAQHTGVVVSSLLGSTLPFDSHTCAMWRALAAEPGLTAQILEQLLEKVTGDVPYKESRAFLLGGSSERVATPLPMAATCALHEIMSAPESGPAVLGLYAPLFVTLLLRVSCTVGVQLPKSLQGRERKSSSSSNAATSRSLQPCSCAVQTLRAMLARGGSEAVAAAVGSAGGWELMENPERHHEGIAVLAGSMARHAGPRLPLIVKSLIPTLSSAFDSQRVTATAFLAELLSSNVVNDLMLLEGVMDSMTGRQKDPCLLVRVLALRGLGNIAVGAPEKVHKHGAKLLASMVNGMDDRDDPNNLVALEAMTSLSKLLEHLEERDVQAMLLHIAIRIRPFFDSEQPDLRRSSIVLFGNLTKFSEGDCEAFFEQILNGLVTLLLHLQDPKPEVVRACKFALRMCGPNMGCEGLCDMFLNHLREDRSLHYGEFMNNVCKHLMQSYPEMLNRLVLTNLFYFKSTWVDIRAAAPMFIGFLVLHVGEDHCHQVDLEQLISALNLLLKDPVPAVRMKVAETLGRLVRIL", "length": 1802, "header": "tr|A0A8V0YAY2-1|A0A1D5PUD1_CHICK Computationally mapped isoform of Maestro heat like repeat family member 1 OS=Gallus gallus OX=9031 GN=LOC101749352 PE=1 SV=1 CANONICAL=A0A1D5PUD1-1" }, "locus": { "chromosome": "2", "start_pos": 148536863, "end_pos": 148439101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022674.1", "url": "https://www.ensembl.org/id/ENSGALT00010022674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013090.1", "url": "https://www.ensembl.org/id/ENSGALP00010013090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749352", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749352", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV05-1", "protein_name": "Maestro heat-like repeat family member 1", "gene_name": "Mroh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRPYIKKLSFTLLDSITDKDPMVQEQVCSALCSLGEAQPDETLRACEEYLRQHDKLAHPYRTKILRAMETILSSHIHDLDKDTASAVILLASSEMTRTKELDCDWQQAASSVLVAVGKRFTNQVMEEVLNRFQPGMLPHSSVLHTLANLSMSNAFDMVPFLPSILSTMLPMLGMAKQDALKVVFCCALQHFSESILEYLANLDQAPDPTVRKDTFGADIFGAYDFLFHHWLQSRDAKLRLAVVAALGPMSHLLPSERLEEQLPKLLPAVLGLYKKHAETFQISKQSLGQILEAAVNVSSRTLEVQLEALLVALHSQICVPVESSSPLVMNSQKEVLRCFTVLACCSPDRLLAFLLPRLDTNNERLRVGTLQILRHIVNSAAAQMEIKKPFILSSMRLPLLDTNDKVKRAVVQVISAMAHHGYLEQPGGEVMVEYIVQQCALPAEEPQKPGPDGEDLAADSVRAVSIRTLYLVSTTVDRMNSVLWPYLLEFLTPVRFTGALTPLCRSLVHLALKRQEAGADDFLIQYNANANLPSPFALTTRLLVVSSNPYLGDGRGAASLRLLKVMHQNIHPLLGQRWETTMPVLLEYLDEHTEETLSLKEWEEKLLVFLRDTLIMVSDNVWICQLSQEMCKQLPSYSGTPQEKNFLYKCIGTTLGAASSKEVVRKHLRELLETARYQEETEKEGLACCFGICAITHLEDTLAQLEDFVRSDVFRKSTSIFSIFKDRSEHEVEKLKSSLILCYGHVAAQAPRELMLAKVESDILRSIFQCFNTKVLGIKVETKDPALKLCLVQSLCMVSQAMCSGAQASSFHFSRKAELVAQMMEFIRAEPQDYLRTPIRKKAMLACTYLVTLEPALEEQTQADVIHSCLHSVMALPPGPEGEDGVCQESLYLDTVCALEDLLTSLLRQNMTPQGLQIMVEHLSPWIKSPRGHERARALGLGACLLQFFLEHLQVSTLVPFHNLGLLVGLFAPRCADTWTTTRQEAVGCVYSLLYLQLGYEGFSRDHRDDVAERLLTLKDGLVHADPTILFHTCHSIAQVIAKRLPSDQLISLLLTMFESLGDPDKNCSRAATVMINCLLKERGNVLLEKVPEIVSVLRAKLRDTQEEHVLPAAQHSVYLLASQHCEAVVSSLLGSPLPFDSHTCALWRALAVEPSLTAQVLELLLEKMSKDVPFKESRAFLLGSTADRVATLLPLAATCALNEVLSAPSSGTVVLELYPQLFVALLLRVSCTVGVQLPRNLQAKERKSTSLAKAARNLDPCSSAVDALQALLLRSGSQDVLRCVELEGGWELLRTSAGHEDGVAQLASSMAKYAGPRLPLVMKALGCTQNSVYEIQRVTSTAFLAELLSSNVVNDLMLLEPLLDNLTARLKDSSASVRRLVLRGLANMASGSPDKVQAHGPQLMTAMVSGLDDGDEPHSLVALEAMVGLSRLLDLVEPWDLRLVLLHTTIRIRPFFDSEKVEFRTASIRLFGHLNKACPGECEDVFLEQVVGGLVPLLLHLRDPQVPVASACKFALCMCVPHLECAELAAAFYKYLQEGRSVHFGEFLNSTCKHLMHHFPDLLGRLVSTNLFYFKSSWDDVRAAAPMFTGFLVLHAEPEQRTQVDLEQLIVALQLLLKDPVPGVREKAAETLGRLVKFA", "length": 1641 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E0CZ22-1", "protein_name": "Maestro heat-like repeat-containing protein family member 1", "gene_name": "Mroh1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRPYIKRLSFTLLDSITDKDPMVQEQVCSALCSLGDAQPDETLHACEEYLRQHDKLAHPYRTKILRAMETVLSSHIHDLDKDTAGAVILLATSEMTRTKELDCDWQQAAGSVLVAVGKRFTNQVMEEVLSRFQPGMLPHSSVLHTLANLSVSNAFDMVPFLPSILSTMLPMLSMAKQDALKVVFCGALQHFSESILEYLANLDQAPDPTVRKDTFGADIFGAYDVLFHHWLQSRDAKLRLAVVAALGPMSHLLPSERLEEQLPKLLPAVLGLYKKHAEAFQISKSLGQILEAAVNVSSRTLEVQLDALLVALHAQICVPVESSSPLVMNSQKEVLRCFTVLACCSPDRLLAFLLPRLDTSNERLRVGTLQILRHIINSAAAQMEAKQPFILSSMRLPLLDTNDKVKRAVVQVISAMAHHGYLEQPGGEVMVEYIVQQCALPAEEPEKPGPDGEDLAADSVRAVSIRTLYLVSTTVDRMNSVLWPYLLEFLTPVRFTAALTPLCRSLVHLALKRQEAGADDFLIQYNANANLPSPFAMTTRLLVVSSNPYLGDGRGAASLRLLKVMHQNIHPFLGQRWETTMPMLLEYLDEHTEESLSLKEWEEKLLMFLRDTLAVVSDNIWICQLSQEMCKQLPSYSGTPQEKNFLYKCIGTTLGAASSKEVVRKHLRELLETARYQEEAEQEGLACCFGICAITHLEDTLAQLEDFVRSDVFRKSTGIFSIFKDRSEHEVERMKSCLILCYGHVAAQAPRELVLARVESDILRSMFQCFNTKVLGIKVETKDPALKLCLVQSLCMVSQAMCSSAQASSFHFLRKTELVTQMMEFIRAEPPDCLRTPIRKKAMLACTYLVNLEPALEEQTQADVVHSCLHSVMALPPEAEGGDGVGREPLYLDTVCALEDLLTRLLRQNMTPQGLQIMVEHLSPWIKSPRGHERARALGLGACLLEFFQEHLLVSTLVPFHNLGLLVGLFAPRCADTWTTTRQKAVGCVYSLLYLQLGYEGFSRDHRDDVAERLLTLQDGLVNADPTILFHTCHSIAQVIAKRLPSDQLISLLLTVFESLGDPDKNCSRAATVMINCLLKERGNVLLEKVPEIVSVLRAKLRDTQEEHVLPAAQHSVYLLASQHCEAVVSSLLGSPLPFDSHTCALWRALAVEPGLTAQVLELLLEKMSKDVPFKESRAFLLGSTADRVATLLPLAATCALYEVLSAPSSGTVVLELYPQLFAALLLRVSCTVGVQLPRNLQAKERRSTSPARAARNLDPCSSAVDALQALLLRSGSQDMLRCVELERGWELLKTSAGHEDGVAQLASSMAKYAGPRLPPVTKALACTQNSVYEIQRVTSTAFLAELLSSNVVNDLMLLEPLLDNLTARLKDSSASVRRLVLRGLANMASGSPDKVRAHGPQLLTAMVSGLDDGDEPHSPVALEAMVGLSRLLDLVEPWDLRLVLLHTTIRIRPFFDSEKVEFRTASIRLFGHLNKACHGDCEDVFLEQVVGGLVPLLLHLRDPQVPVASACKFALCMCVPHLECAELAAAFYKYLQEGRSVHFGEFLNSTCKHLMHHFPDLLGRLVSTNLFYFKSSWDDVRAAAPMFTGFLVLHAEPEQKTQVDLEQLIVALQLLLKDPVPGVREKAAETLGRLVKFA", "length": 1640 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F4IP13-1", "protein_name": "Protein SHOOT GRAVITROPISM 6", "gene_name": "SGR6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASSSLGSSIPAPEAVQLLVSSLADDSSVVREASMASLRDIASLNPLLVLDCCYAVSRGGRRRFGNMAGVFQVMAFSVGALEKGESDSVFMGKLAKIATAEIISSKELNADWQRQASGLLVSIGTHFPDLMMEEIFLHLSGPATAAPAMVQILADFASSDALQFTPRLKGVLSKVSPILGNVRDIHRPIFANAFKCWSQAVWLYITDLTSDSPLDSDVMSFLNSVFELLLRVWAVSRDHKVRVSTVDALGQMVGLITRTQLKSALPRLIPAILELYKKDHDDALLATCSLHNLLNASLLSESGPPLLDFEDLTIVLSTLLPVIGINNERKRFSDISVGRKTYNEVQRCFLTVGLVYPEDLFTFLLNKCKLKEDPLTFGALCILKHLLPRLFEAWHSKRPLLVDTASSLLDEQSLAVRKALSELIVVMASHCYLVGPSGELFVEYLVRHSAIGESDHLKAKGELVSPTQLRAVCGKGLLLLTVTIPEMELSDFNAKEYMKLQYILWPFLLKMIIPKVYTGAVASVCRCITELCRRRSSTTPMLIECKARADIPNPEELFTRLVVLLHNPLAKEQLASQILTVLGYLSPLFPKNISMFWQDEIPKMKAYVYDTEDLKLDPTYQETWDDMIINFLAESLDVTQDADWVISLGNSFAKQYILYAPDDDHAALLHRCIGILLQKVNDRAYVRDKIDWMYEQADISIPANRLGLAKAMGLVAASHLDTVLEKLKIIVDNVGQSIFQRILSLFSESYKTEDSDDIHAALALMYGYAAKYAPSSVIEARIDALVGTNMLSRLLHVRQQTAKQAVITAIDLLGRAVINAAETGATFPLKRRDQMLDYILTLMGRDENEGFAESSLEVLHTQALALNACTTLVSVEPKLTIETRNRVMKATLGFFALPNDPSDVISPLIDNLVTLLCAILLTSGEDGRSRAEQLLHLLRQLDQYVSSPIDYQRKRGCVAVHEMLLKFRKLCVGGYCALGCSGDCPHRKYADRSMQGNFSNLPSVFLFPDREVLCLGDRVITYLPRCADTNSEVRKISAQILDQFFSISLSLPKAVLTSGLDSEDSYKALSSLEDVIAILKSDASIDPSEVFNRIVSSICSLLTEHELVAALHSCTAAICDKIRQSAEGAIQAVTEFVSRRGSQLSDNDISRTTHSLLSAAVHITDKNLRVEAIGAISALAENTQSSIVFNEVLATAGKDIVTKDITRMRGGWPMQDAFYAFSQHTELSVLFMEHLISILNRSSLVKSDSHKGENTSSSSETHVEDDILQAAIFALTAFFRGGGKIGKKAVEKSYSSVVGALTLQLGSCHGLASSGQQDPLRVLLTSFQAFCECVGDLEMGKILARNGEQIEKEKWVGLIGDIAGCISIKRPKEVRHICMILTKALNRPQRFQREAAAAALSEFIRYSGDFSSVMEEMVEALCRHVSDDSPTVRRLCLRGLVQMPSACMSHYTTQVIGVILALLDDLDESVQLTAVSCLLMVTESASNDAVEPILLNLSVRLRNLQVSMDPKMRANAFSALGALSKYATGGQREGFVEQIHSTLPRLVVHLHDDDPSIRQACRVTLKRFAPLVDIINYSTLYDSRAFGSEDRTDYENFVRDLSKHLVQESERVDTYMASTIQAFDAPWPVIQANAIHFSTTMLSLSEDQHIISLYYPQVFETLVSKMTRSQDSVVRAACSSAFGLLLRSSKSTLWRGARLDGTDSGRKANDLESVKK", "length": 1716 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54F23-1", "protein_name": "Maestro heat-like repeat-containing protein family member 1", "gene_name": "mroh1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKKNQQISPVLDNIVTSLLQSLSDSDESVRSTVVNSLYEIGFRQPNFVLQVACDYINKNQKIDQTHRVKILNSILQILEQTRNQLTDALSLNLIAMSISEMTRDKEVVPDWQQVASSLLVSLGLRYPSQIMDELLKRFEPGTLPHYFVMKTLGDFISSNPIPTVPKIREILSRILPVLGTIKHDNFKWVFAAALGHFADAIVQYVANIDTAPDKSLTLYSFSSEFYPALELMFSKWLGTNHEKVRLVTIEAVGSICSILSVEQLESQIQKLVVGVLSMLKKEKDLLPVTHSLCCILEVCVKNDLKLQVNELLIPIMTTLHPLVCIVPDYSNPASTKTYNEVLRCFEVIGRGYSDVLISFLNQRLENRDLRSRAGSLSIIRHIVTRLDVELADKKPLILSAIKPLIQTEPSLFIKKYLAQIIIAMAPYGYLEMEGGLTLLEFIVKGSSWYQDSEIGKAQPTQPPKKIENPDLHVTDSELRLICDNILNLITTTMPQLESILWPYLFEFILPEQYTAAIPVVTKSLTYIALSKKSVDSDDYYIDFDKEINLPKPTQIIARYFVLLTAPLRRNQLGIRILENMKAIGPILHPSICDMWDVTLPKLISYLEDHTDIETWNKNQWEELVLRLLSETIKNAADDEWTVALGNSMSEQIDHYKKDPILKRSLYKQMGLIMQKCSHKEFVKSKIEVMFTSVDYTNSLENEGCAIGLGYCGASHFDIVLEKINFYIKNSMVKKSGFFGKKGPKGIKNCILLSLGYSATYAQSALFSSRVEVHVIQPIKPSILQLKKVPKKLSSIKMIDLIGKALHPNKASTFIFKQRDELMKLLISYMSTPPPSTNNQVKIDGTNACSTLVNLEPMISLELEVQIINLSLSFFNQQVSPANATNTDSDEYKEVNSLITSVNNLLSTILYNQTTIACLNRLIGYLDPLSRSKDAHIRERSLFCILYLVKKFIEYSTDSDSMPTDKLFDSIGTTLSVLIPRCTDPEINVRRYAVESIQLILYIGFMLKNATPDNRRVKPSEVLHPLTSIRDSITTTEVNEQFSLVFEISVIISKMISLEEIPKFLEGSIKGLQDLQAFSTNGSCIIINGLIKTRGEELIEYVPILVKGLLTAMEGITSETTMNGTLVSLRSLANHHLIPVLSVLLEYPMPHSVHVIKSFQIIAKDKNLISPTLIHLMDLLNNKPVYEEKPDPKNKNRIIPQPFAIALAATCSLGEIFQLTEVEEVVKYFYHQLISTLVLRAGTCNNSLPCLIEVASTNPKAKASAISLIPSQQMLVTFRQFFKCTKEEETLLAEIESKGSFSQLETPFYHQGIIEILSVVSSHHPDLIQGIFQYLLPYQRSNHLEHRIVTISVTTELINHCKDKELIQRLINTLLNSLVDPLVKLISLKGLSNIVSAGVEQTNRYAPTVIDALSTSIDDQDETMAMECMLGLSKIFEVADEGRVAPILVNICNRIRPAFEKPNDSIRAASFQLFGSLWRFGSGSACDPFYEQIHSSLPSLIMHLNDDVQSVKNSCKKTLFQLSTLMRSQDAMDYFNNKSKGFVGDNDQPNYEEFLLDFSKLLIINYPERVNYFVMTVIEFFKSTWVNLRGNAATFIGFILGNLTEDKRTQTNINSTILTKSLVGLLAEKSPAVRKKAAESLGLLHHY", "length": 1647 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NDA8-1", "protein_name": "Maestro heat-like repeat-containing protein family member 1", "gene_name": "MROH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAAAQMEDKKPFILSSMRLPLLDTNSKVKRAVVQVISAMAHHGYLEQPGGEAMIEYIVQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCRSLVHLAQKRQEAGADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREGLACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKVLGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADVIHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA", "length": 1641 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W350-1", "protein_name": "C11.1, isoform B", "gene_name": "c11.1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 1742 }, "evidence": [ { "id": "A0A1D5PUD1", "url": "https://omabrowser.org/oma/group/A0A1D5PUD1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane destabilizing activity", "id": "GO:0140912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140912", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lysosome fission", "id": "GO:0170064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170064", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1482, "end_pos": 1484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" }, { "id": "PF23210", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MROH2B-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 915, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" }, { "id": "PF23221", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MROH2B-like N-terminal HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 250, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" }, { "id": "PF21047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 939, "end_pos": 1168, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUD1" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 1372, "end_pos": 1643, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 1482, "end_pos": 1484 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 765, "end_pos": 767 }, { "start_pos": 960, "end_pos": 962 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P9X1-1", "uniprot_ac": "A0A1D5P9X1", "uniprot_id": "A0A1D5P9X1_CHICK", "mass": { "chemical_mass": 59501.0, "monoisotopic_mass": 59501.0 }, "refseq": { "ac": "XP_015151247", "name": "protein FAM222B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" }, "gene_names": [ { "name": "FAM222B", "type": "recommended", "evidence": [ { "id": "A0A1D5P9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1" } ] }, { "name": "C17orf63", "type": "synonym", "evidence": [ { "id": "XP_015151247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" } ] }, { "name": "C19H17ORF63", "type": "synonym", "evidence": [ { "id": "XP_015151247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" } ] }, { "name": "FAM222B", "type": "synonym", "evidence": [ { "id": "XP_015151247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 222 member B", "type": "synonym", "evidence": [ { "id": "A0A1D5P9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1/entry#names_and_taxonomy" } ] }, { "name": "protein FAM222B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015151247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9X1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM222B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1", "locus": { "chromosome": "19", "start_pos": 6310469, "end_pos": 6341777, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029224", "url": "https://www.ensembl.org/id/ENSGALG00010029224" } ] } } ], "crossref": [ { "id": "A0A1D5P9X1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P9X1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041939", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041939", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417578", "url": "https://www.ncbi.nlm.nih.gov/gene/417578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P9X1", "url": "https://www.orthodb.org/?gene=A0A1D5P9X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIU6", "url": "https://www.orthodb.org/?gene=A0A8V1AIU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKY5", "url": "https://www.orthodb.org/?gene=A0A8V1AKY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151247", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P9X1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P9X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLACLPGPGDLSFQLLSYTQMNTGLQKWDTTQKMRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSGQRYSPYPSQATTKTGLLAIVKSPAKGIIKDFDGTRTRLLPEAMMNPPSTPYVAPSTLTHPQALARQQALQHAQTLPHPQSIPQPQTLQHPQGIPQPQSLPHPQGIPQALPHPQTMQQPQGLQHPQTMAHQALQPPPNPLLQPGLHGSRKMPDADAPPNVTVSTSTIPLSMAATLQQNQPPDLSSIVHQINQFCQARAGISTTSVCEGQIANPSPISRNLLINASTRVSTHNVPTPMPSCVVNPVDHAAAAIPSASVNVPMVNINRVPPAYQNEIKSVAWNQHQLAHLQQMCGDAAGPAALAGKHAAREMAGQSFPGKTSSYPQELCMGQSFGLKPPIEKPTPSPPVNGLQGPLPYTNGHYFQPMWNNILPTPNSDSSGSQDLAMPFHGGQPAGAALDCAGGPHYRAGAGPASQNNVMQTVDYLSGDFQQPCFREQSMAVLGKVHRPPMNRAPEPSDSRNLHIQHPGYR", "length": 553, "header": "tr|A0A1D5P9X1-1|A0A1D5P9X1_CHICK Isoform 1 of Family with sequence similarity 222 member B OS=Gallus gallus OX=9031 GN=FAM222B PE=4 SV=1 CANONICAL=A0A1D5P9X1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P9X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1/entry", "sequence": { "sequence": "MLACLPGPGDLSFQLLSYTQMNTGLQKWDTTQKMRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSGQRYSPYPSQATTKTGLLAIVKSPAKGIIKDFDGTRTRLLPEAMMNPPSTPYVAPSTLTHPQALARQQALQHAQTLPHPQSIPQPQTLQHPQGIPQPQSLPHPQGIPQALPHPQTMQQPQGLQHPQTMAHQALQPPPNPLLQPGLHGSRKMPDADAPPNVTVSTSTIPLSMAATLQQNQPPDLSSIVHQINQFCQARAGISTTSVCEGQIANPSPISRNLLINASTRVSTHNVPTPMPSCVVNPVDHAAAAIPSASVNVPMVNINRVPPAYQNEIKSVAWNQHQLAHLQQMCGDAAGPAALAGKHAAREMAGQSFPGKTSSYPQELCMGQSFGLKPPIEKPTPSPPVNGLQGPLPYTNGHYFQPMWNNILPTPNSDSSGSQDLAMPFHGGQPAGAALDCAGGPHYRAGAGPASQNNVMQTVDYLSGDFQQPCFREQSMAVLGKVHRPPMNRAPEPSDSRNLHIQHPGYR", "length": 553, "header": "tr|A0A1D5P9X1-1|A0A1D5P9X1_CHICK Isoform 1 of Family with sequence similarity 222 member B OS=Gallus gallus OX=9031 GN=FAM222B PE=4 SV=1 CANONICAL=A0A1D5P9X1-1" }, "locus": { "chromosome": "19", "start_pos": 6322189, "end_pos": 6315481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070629.1", "url": "https://www.ensembl.org/id/ENSGALT00010070629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043320.1", "url": "https://www.ensembl.org/id/ENSGALP00010043320.1" } ] } }, { "isoform_ac": "A0A8V1AIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU6/entry", "sequence": { "sequence": "MWRSWPVTGFVRPKTLLEAQVCSLGRILPDAELGLCWSSGTKGFLLVWEMQLSPPGSHSVSPLAACPLCPGVGPVLPTLGTDVFPFSAGDTTQKMRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSGQRYSPYPSQATTKTGLLAIVKSPAKGIIKDFDGTRTRLLPEAMMNPPSTPYVAPSTLTHPQALARQQALQHAQTLPHPQSIPQPQTLQHPQGIPQPQSLPHPQGIPQALPHPQTMQQPQGLQHPQTMAHQALQPPPNPLLQPGLHGSRKMPDADAPPNVTVSTSTIPLSMAATLQQNQPPDLSSIVHQINQFCQARAGISTTSVCEGQIANPSPISRNLLINASTRVSTHNVPTPMPSCVVNPVDHAAAAIPSASVNVPMVNINRVPPAYQNEIKSVAWNQHQLAHLQQMCGDAAGPAALAGKHAAREMAGQSFPGKTSSYPQELCMGQSFGLKPPIEKPTPSPPVNGLQGPLPYTNGHYFQPMWNNILPTPNSDSSGSQDLAMPFHGGQPAGAALDCAGGPHYRAGAGPASQNNVMQTVDYLSGDFQQPCFREQSMAVLGKVHRPPMNRAPEPSDSRNLHIQHPGYR", "length": 614, "header": "tr|A0A8V1AIU6-1|A0A1D5P9X1_CHICK Computationally mapped isoform of Family with sequence similarity 222 member B OS=Gallus gallus OX=9031 GN=FAM222B PE=4 SV=1 CANONICAL=A0A1D5P9X1-1" }, "locus": { "chromosome": "19", "start_pos": 6317322, "end_pos": 6315481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070626.1", "url": "https://www.ensembl.org/id/ENSGALT00010070626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043317.1", "url": "https://www.ensembl.org/id/ENSGALP00010043317.1" } ] } }, { "isoform_ac": "A0A8V1AKY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY5/entry", "sequence": { "sequence": "MRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSGQRYSPYPSQATTKTGLLAIVKSPAKGIIKDFDGTRTRLLPEAMMNPPSTPYVAPSTLTHPQALARQQALQHAQTLPHPQSIPQPQTLQHPQGIPQPQSLPHPQGIPQALPHPQTMQQPQGLQHPQTMAHQALQPPPNPLLQPGLHGSRKMPDADAPPNVTVSTSTIPLSMAATLQQNQPPDLSSIVHQINQFCQARAGISTTSVCEGQIANPSPISRNLLINASTRVSTHNVPTPMPSCVVNPVDHAAAAIPSASVNVPMVNINRVPPAYQNEIKSVAWNQHQLAHLQQMCGDAAGPAALAGKHAAREMAGQSFPGKTSSYPQELCMGQSFGLKPPIEKPTPSPPVNGLQGPLPYTNGHYFQPMWNNILPTPNSDSSGSQDLAMPFHGGQPAGAALDCAGGPHYRAGAGPASQNNVMQTVDYLSGDFQQPCFREQSMAVLGKVHRPPMNRAPEPSDSRNLHIQHPGYR", "length": 520, "header": "tr|A0A8V1AKY5-1|A0A1D5P9X1_CHICK Computationally mapped isoform of Family with sequence similarity 222 member B OS=Gallus gallus OX=9031 GN=FAM222B PE=4 SV=1 CANONICAL=A0A1D5P9X1-1" }, "locus": { "chromosome": "19", "start_pos": 6317040, "end_pos": 6315481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070625.1", "url": "https://www.ensembl.org/id/ENSGALT00010070625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043316.1", "url": "https://www.ensembl.org/id/ENSGALP00010043316.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9X1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 307, "end_pos": 309 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PGZ5-1", "uniprot_ac": "A0A1D5PGZ5", "uniprot_id": "A0A1D5PGZ5_CHICK", "mass": { "chemical_mass": 25494.0, "monoisotopic_mass": 25494.0 }, "refseq": { "ac": "NP_001264571", "name": "sel1 repeat-containing protein 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" }, "gene_names": [ { "name": "COA7", "type": "recommended", "evidence": [ { "id": "A0A1D5PGZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ] }, { "name": "C1orf163", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "name": "C8H1orf163", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "name": "COA7", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "name": "SELRC1", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly factor 7", "type": "recommended", "evidence": [ { "id": "A0A1D5PGZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5/entry#names_and_taxonomy" } ] }, { "name": "Sel1 repeat containing 1", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "name": "sel1 repeat-containing protein 1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "name": "sel1 repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX929935.2, BX931563.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On or before Apr 13, 2013 this sequence version replaced XP_426661.2, XP_001234293.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_001264571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571" } ] }, { "annotation": "Required for assembly of mitochondrial respiratory chain complexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q3#function" }, { "database": "UniProtKB", "id": "RU366075", "url": "https://www.uniprot.org/uniprotkb/RU366075#function" }, { "database": "UniProtKB", "id": "A0A1D5PPW6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPW6#function" }, { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COA7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5", "locus": { "chromosome": "8", "start_pos": 24190998, "end_pos": 24193309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024996", "url": "https://www.ensembl.org/id/ENSGALG00010024996" } ] } } ], "crossref": [ { "id": "A0A1D5PGZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PGZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040910", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040910", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "429105", "url": "https://www.ncbi.nlm.nih.gov/gene/429105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429105", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGCINAG", "url": "https://omabrowser.org/oma/group/PGCINAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGZ5", "url": "https://www.orthodb.org/?gene=A0A1D5PGZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPW6", "url": "https://www.orthodb.org/?gene=A0A1D5PPW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5Q3", "url": "https://www.orthodb.org/?gene=A0A8V1A5Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13891:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13891:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPW6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLIDFGDEEEVRSYLENLHVEYSYQCFKEKDPEGCQRLADYLDAVKKDFEAAARVLRDNCELHGHSESCYRLGAYQAIGKGGLAADLKAAYKSFLKSCEKGGKKSVNACHSVGLLAHDGRVNDDKPDPVVARDYYTKACDGNFAPSCFNLSVIYLQGAAGVPKDMNRALKYSLKGCELGHIWACANASRMYKLGDGVEKNDDKAEDLKNRAKQLHKEQKEASSSLTFGE", "length": 231, "header": "tr|A0A1D5PGZ5-1|A0A1D5PGZ5_CHICK Isoform 1 of Cytochrome c oxidase assembly factor 7 OS=Gallus gallus OX=9031 GN=COA7 PE=1 SV=1 CANONICAL=A0A1D5PGZ5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5/entry", "sequence": { "sequence": "MAGLIDFGDEEEVRSYLENLHVEYSYQCFKEKDPEGCQRLADYLDAVKKDFEAAARVLRDNCELHGHSESCYRLGAYQAIGKGGLAADLKAAYKSFLKSCEKGGKKSVNACHSVGLLAHDGRVNDDKPDPVVARDYYTKACDGNFAPSCFNLSVIYLQGAAGVPKDMNRALKYSLKGCELGHIWACANASRMYKLGDGVEKNDDKAEDLKNRAKQLHKEQKEASSSLTFGE", "length": 231, "header": "tr|A0A1D5PGZ5-1|A0A1D5PGZ5_CHICK Isoform 1 of Cytochrome c oxidase assembly factor 7 OS=Gallus gallus OX=9031 GN=COA7 PE=1 SV=1 CANONICAL=A0A1D5PGZ5-1" }, "locus": { "chromosome": "8", "start_pos": 24192470, "end_pos": 24191183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061036.1", "url": "https://www.ensembl.org/id/ENSGALT00010061036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037766.1", "url": "https://www.ensembl.org/id/ENSGALP00010037766.1" } ] } }, { "isoform_ac": "A0A1D5PPW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPW6/entry", "sequence": { "sequence": "MAGLIDFGDEEEVRSYLENLHVEYSYQCFKEKDPEGGLAADLKAAYKSFLKSCEKGGKKSVNACHSVGLLAHDGRVNDDKPDPVVARDYYTKACDGNFAPSCFNLSVIYLQGAAGVPKDMNRALKYSLKGCELGHIWACANASRMYKLGDGVEKNDDKAEDLKNRAKQLHKEQKEASSSLTFGE", "length": 184, "header": "tr|A0A1D5PPW6-1|A0A1D5PPW6_CHICK Computationally mapped isoform of Cytochrome c oxidase assembly factor 7 OS=Gallus gallus OX=9031 GN=COA7 PE=1 SV=1 CANONICAL=A0A1D5PGZ5-1" }, "locus": { "chromosome": "8", "start_pos": 24192470, "end_pos": 24191183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061031.1", "url": "https://www.ensembl.org/id/ENSGALT00010061031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037762.1", "url": "https://www.ensembl.org/id/ENSGALP00010037762.1" } ] } }, { "isoform_ac": "A0A8V1A5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Q3/entry", "sequence": { "sequence": "MLAAGREAAPIPPPLKAPHRAACRPLAAPYAFPARSDLLRRGRVCLLPQSRRGALPAAFSLKLICAAEGAAAESGAGGGGPGPTSGWRPRSMAGLIDFGDEEEVRSYLENLHVEYSYQCFKEKDPEGCQRLADYLDAVKKDFEAAARVLRDNCELHGHSESCYRLGAYQAIGKGGLAADLKAAYKSFLKSCEKGGKKSVNACHSVGLLAHDGRVNDDKPDPVVARDYYTKACDGNFAPSCFNLSVIYLQGAAGVPKDMNRALKYSLKGCELGHIWACANASRMYKLGDGVEKNDDKAEDLKNRAKQLHKEQKEASSSLTFGE", "length": 322, "header": "tr|A0A8V1A5Q3-1|A0A1D5PGZ5_CHICK Computationally mapped isoform of Cytochrome c oxidase assembly factor 7 OS=Gallus gallus OX=9031 GN=COA7 PE=1 SV=1 CANONICAL=A0A1D5PGZ5-1" }, "locus": { "chromosome": "8", "start_pos": 24193159, "end_pos": 24191183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061039.1", "url": "https://www.ensembl.org/id/ENSGALT00010061039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037769.1", "url": "https://www.ensembl.org/id/ENSGALP00010037769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429105", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429105", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TD90-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECNYQCYREKDPDGCYRLVDYLEGIQKNFDEAAKVLKFNCEENKHSDSCYKLGAYYVTGKGGLSQDLKAASNCFLMACEKPGKKSTEACHNVGLLAHDGQVNEDGQPNLERARDYYTRACDGNYAASCFNLSAMFLQGAPSFPKDMGLACKYAMKACDLGHVWACANASRMYKLGDGVDKDEAKAEELKNRARQLHKEQQKSVQPLTFG", "length": 231 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4AC65-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "Coa7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECHYQCYREKDPEGCYRLVDYLEGIQKNFDEAAKVLKFNCEKYGHGDSCYKLGGYYVTGKGGLTQDLKAAFSCFLMACEKPGKKSVESCHNVGLLAHDGQVNEDGQPDLGKARDYYTRACDGSYAASCFNLSAMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEMLKNRAQQLHKEQQKNVQPLTFG", "length": 231 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GW05-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "LOC100756398", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMKVECHYQCYREKDPDGCYRLVDYLEGIQKNFDEAAKVLKFNCEDNGHSDSCYKLGAYYVTGKGGLTQDLKAASACFLMACEKPGKKSVESCHNVGLLAHDGQINEDGQPDLRKARDYYTRACDGNYAASCFNLSTMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEMLKNRAQQLHKEQQKNVQPVTFG", "length": 231 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LRZ7-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECNYQCYQEKDPDGCYRLVDYLEGIQKNFNEAAKVLKFNCEENKHSDSCYKLGAYYVTGKGGLTQDLKAASSCFLMACEKPGKKSVEACHNVGLLAHDGQVNEDGQPDLPRARDYYTRACDGNYASSCFNLSTMFLQGPGFPKDMGLACKYSMKACDLGHVWACANASRMYRLGDGVDKDEAKAEELKNRARQLHKEQQKSVQPLTFG", "length": 230 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TYQ3-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "coa7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGLINFEDEQEVKQFLDNLGVEYSYQCYREKDPEGCHRLADYLEGVKKNYESTAQVLQHNCEVNAHAQSCYKLGAYHVTGKGGMKKCLKTAYSCFLKSCNTQGKKSVDACHNVGLLAQDGRALETGPDTTVARQYFEKACEGGFAPSCFNLSTLYIQGFPGLDKSMPLALKYALKACDLGHVWGCANASRMYKLGDGTDKDEQRAEELKNRAKDLHGQEKERQLKFGE", "length": 229 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q921H9-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "Coa7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECHYQCYREKDPEGCYRLVDYLEGIQKNFDEAAKVLKFNCEKYGHGDSCYKLGAYYVTGKGGLTQDLKAASSCFLMACEKPGKKSVESCHNVGLLAHDGQVNEDGQPDLGKARDYYSRACDGGYAASCFNLSAMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEVLKNRARQLHKEQQKNVQPLTFG", "length": 231 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BR5-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGMVDFQDEEQVKSFLENMEVECNYHCYHEKDPDGCYRLVDYLEGIRKNFDEAAKVLKFNCEENQHSDSCYKLGAYYVTGKGGLTQDLKAAARCFLMACEKPGKKSIAACHNVGLLAHDGQVNEDGQPDLGKARDYYTRACDGGYTSSCFNLSAMFLQGAPGFPKDMDLACKYSMKACDLGHIWACANASRMYKLGDGVDKDEAKAEVLKNRAQQLHKEQQKGVQPLTFG", "length": 231 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W5N0-1", "protein_name": "Cytochrome c oxidase assembly factor 7 homolog", "gene_name": "Coa7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAYDLKKESDVKEYVEKLGVEYRFGCYSEKKPEACHLLGDYLEGIKKDFEKASKVYKSTCDDYGYAKSCYKYGNYSFLGKGKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWNVPKGLEFLTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPPAGQPPLKDSDYIVLKDMKKAFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKYKKLALEMQDEVKKQHDTLGFQQGVGMPN", "length": 266 }, "evidence": [ { "id": "A0A1D5PGZ5", "url": "https://omabrowser.org/oma/group/A0A1D5PGZ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ], "pmid": "" }, { "name": "respiratory chain complex IV assembly", "id": "GO:0008535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008535", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PY18-1", "uniprot_ac": "A0A1D5PY18", "uniprot_id": "A0A1D5PY18_CHICK", "mass": { "chemical_mass": 33028.0, "monoisotopic_mass": 33028.0 }, "refseq": { "ac": "XP_015130643", "name": "syntaxin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" }, "gene_names": [ { "name": "STX2", "type": "recommended", "evidence": [ { "id": "A0A1D5PY18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ] }, { "name": "EPIM", "type": "synonym", "evidence": [ { "id": "XP_015130643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" } ] }, { "name": "STX2", "type": "synonym", "evidence": [ { "id": "XP_015130643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" } ] }, { "name": "syntaxin-2", "type": "synonym", "evidence": [ { "id": "XP_015130643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" } ] } ], "protein_names": [ { "name": "Syntaxin-2", "type": "recommended", "evidence": [ { "id": "A0A1D5PY18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18/entry#names_and_taxonomy" } ] }, { "name": "Epimorphin", "type": "synonym", "evidence": [ { "id": "A0A1D5PY18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18/entry#names_and_taxonomy" } ] }, { "name": "syntaxin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015130643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130643", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643" } ] }, { "annotation": "Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18#function" }, { "database": "UniProtKB", "id": "ARBA00060077", "url": "https://www.uniprot.org/uniprotkb/ARBA00060077#function" }, { "database": "UniProtKB", "id": "A0A8V0ZR60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR60#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZU33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU33#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18", "locus": { "chromosome": "15", "start_pos": 3231347, "end_pos": 3169011, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023062", "url": "https://www.ensembl.org/id/ENSGALG00010023062" } ] } } ], "crossref": [ { "id": "A0A1D5PY18", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PY18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002536", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002536", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "378895", "url": "https://www.ncbi.nlm.nih.gov/gene/378895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VLHASHY", "url": "https://omabrowser.org/oma/group/VLHASHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PY18", "url": "https://www.orthodb.org/?gene=A0A1D5PY18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR60", "url": "https://www.orthodb.org/?gene=A0A8V0ZR60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT50", "url": "https://www.orthodb.org/?gene=A0A8V0ZT50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU33", "url": "https://www.orthodb.org/?gene=A0A8V0ZU33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130643", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY18-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDRLADLAECKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITGKTTTDEELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLESSIRELHEMFMDMAMFVETQGEMINNIEKNVMNATDYVEHAKEETKKAVKYQSKARRKLIFIIICVTVLLLILGIILATTLS", "length": 286, "header": "tr|A0A1D5PY18-1|A0A1D5PY18_CHICK Isoform 1 of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=2 CANONICAL=A0A1D5PY18-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PY18-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18/entry", "sequence": { "sequence": "MKDRLADLAECKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITGKTTTDEELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLESSIRELHEMFMDMAMFVETQGEMINNIEKNVMNATDYVEHAKEETKKAVKYQSKARRKLIFIIICVTVLLLILGIILATTLS", "length": 286, "header": "tr|A0A1D5PY18-1|A0A1D5PY18_CHICK Isoform 1 of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=2 CANONICAL=A0A1D5PY18-1" }, "locus": { "chromosome": "15", "start_pos": 3229381, "end_pos": 3216385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056169.1", "url": "https://www.ensembl.org/id/ENSGALT00010056169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033988.1", "url": "https://www.ensembl.org/id/ENSGALP00010033988.1" } ] } }, { "isoform_ac": "A0A8V0ZKU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU9/entry", "sequence": { "sequence": "MFPLLLGNVHAVCLCKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITGKTTTDEELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLESSIRELHEMFMDMAMFVETQGEMINNIEKNVMNATDYVEHAKEETKKAVKYQSKARRKLIFIIICVTVLLLILGIILATTLS", "length": 290, "header": "tr|A0A8V0ZKU9-1|A0A1D5PY18_CHICK Computationally mapped isoform of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=1 CANONICAL=A0A1D5PY18-1" }, "locus": { "chromosome": "15", "start_pos": 3229381, "end_pos": 3213850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056181.1", "url": "https://www.ensembl.org/id/ENSGALT00010056181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033999.1", "url": "https://www.ensembl.org/id/ENSGALP00010033999.1" } ] } }, { "isoform_ac": "A0A8V0ZR60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR60/entry", "sequence": { "sequence": "MKDRLADLAECKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITGKTTTDEELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLESSIRELHEMFMDMAMFVETQGEMINNIEKNVMNATDYVEHAKEETKKAVKYQSKARRKMWIIIIVSLVLIAVIEIDIHNYMCNCTTSDTWNYPSNNTIIASVF", "length": 307, "header": "tr|A0A8V0ZR60-1|A0A1D5PY18_CHICK Computationally mapped isoform of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=1 CANONICAL=A0A1D5PY18-1" }, "locus": { "chromosome": "15", "start_pos": 3229395, "end_pos": 3216385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056178.1", "url": "https://www.ensembl.org/id/ENSGALT00010056178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033996.1", "url": "https://www.ensembl.org/id/ENSGALP00010033996.1" } ] } }, { "isoform_ac": "A0A8V0ZT50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT50/entry", "sequence": { "sequence": "MLCPFTTLFKYRIQEEKIQQYNCTWMKGSEYNQCKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITSISEYIQNTHNTL", "length": 190, "header": "tr|A0A8V0ZT50-1|A0A1D5PY18_CHICK Computationally mapped isoform of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=1 CANONICAL=A0A1D5PY18-1" }, "locus": { "chromosome": "15", "start_pos": 3224009, "end_pos": 3190985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056190.1", "url": "https://www.ensembl.org/id/ENSGALT00010056190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034008.1", "url": "https://www.ensembl.org/id/ENSGALP00010034008.1" } ] } }, { "isoform_ac": "A0A8V0ZU33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU33/entry", "sequence": { "sequence": "MIWTENNFELNSGCKGNEDGETVIVEKDHFMDDFFQQVEEIRNNITKIAQNVEEVKKQHSIILSAPNPEGRTKEELEELNEEIKKTANKIRARLKAIEQSVDQSENANRTSVNVRIRKTQHSVLAHKFVEVMTEYNETQTLFRERSKGRIQRQLEITGKTTTDEELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLESSIRELHEMFMDMAMFVETQGEMINNIEKNVMNATDYVEHAKEETKKAVKYQSKARRKLIFIIICVTVLLLILGIILATTLS", "length": 289, "header": "tr|A0A8V0ZU33-1|A0A1D5PY18_CHICK Computationally mapped isoform of Syntaxin-2 OS=Gallus gallus OX=9031 GN=STX2 PE=1 SV=1 CANONICAL=A0A1D5PY18-1" }, "locus": { "chromosome": "15", "start_pos": 3229381, "end_pos": 3218269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056161.1", "url": "https://www.ensembl.org/id/ENSGALT00010056161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033982.1", "url": "https://www.ensembl.org/id/ENSGALP00010033982.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BKT9-1", "protein_name": "Syntaxin 2", "gene_name": "STX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRDRLPDLTACRKNDDGDTTVVVEKDHFMDDFFHQVEEIRNSIAKIAQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRTKLKSIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEVMTEYNEAQTLFRERSKGRIQRQLEITGKTTTDDELEEMLESGNPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIEKNVMNAADYVEHAKEETKKAIKYHSKARRKKWIIVAVSLVLVAVIALIIGLSVGK", "length": 288 }, "evidence": [ { "id": "A0A1D5PY18", "url": "https://omabrowser.org/oma/group/A0A1D5PY18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32856-1", "protein_name": "Syntaxin-2", "gene_name": "STX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK", "length": 288 }, "evidence": [ { "id": "A0A1D5PY18", "url": "https://omabrowser.org/oma/group/A0A1D5PY18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50279-1", "protein_name": "Syntaxin-2", "gene_name": "Stx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDRLPDLTACRKSDDGDNAVIITVEKDHFMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDEELEEMLESGKPSIFISDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVVVAVIAVLALIIGLTVGK", "length": 290 }, "evidence": [ { "id": "A0A1D5PY18", "url": "https://omabrowser.org/oma/group/A0A1D5PY18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00262-1", "protein_name": "Syntaxin-2", "gene_name": "Stx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRDRLPDLTACRTNDDGDTAVVIVEKDHFMDGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLDKEIKKTANRIRGKLKSIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFISDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVAVAVIAVLALIIGLSVGK", "length": 289 }, "evidence": [ { "id": "A0A1D5PY18", "url": "https://omabrowser.org/oma/group/A0A1D5PY18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q42374-1", "protein_name": "Syntaxin-related protein KNOLLE", "gene_name": "KN", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNDLMTKSFMSYVDLKKAAMKDMEAGPDFDLEMASTKADKMDENLSSFLEEAEYVKAEMGLISETLARIEQYHEESKGVHKAESVKSLRNKISNEIVSGLRKAKSIKSKLEEMDKANKEIKRLSGTPVYRSRTAVTNGLRKKLKEVMMEFQGLRQKMMSEYKETVERRYFTVTGEHANDEMIEKIITDNAGGEEFLTRAIQEHGKGKVLETVVEIQDRYDAAKEIEKSLLELHQVFLDMAVMVESQGEQMDEIEHHVINASHYVADGANELKTAKSHQRNSRKWMCIGIIVLLLIILIVVIPIITSFSSS", "length": 310 }, "evidence": [ { "id": "A0A1D5PY18", "url": "https://omabrowser.org/oma/group/A0A1D5PY18/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "cornified envelope assembly", "id": "GO:1903575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903575", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY18", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY18" } ], "pmid": "" }, { "name": "SNARE 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The reference sequence was derived from JAENSK010000239.1. 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"MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYKVEQKVFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1488, "header": "tr|A0A1D5PT55-1|A0A1D5PT55_CHICK Isoform 1 of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=2 CANONICAL=A0A1D5PT55-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDV9/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYKVEQKVFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1464, "header": "tr|A0A1D5PDV9-1|A0A1D5PDV9_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052380.1", "url": "https://www.ensembl.org/id/ENSGALT00010052380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031303.1", "url": "https://www.ensembl.org/id/ENSGALP00010031303.1" } ] } }, { "isoform_ac": "A0A1D5PT55-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYKVEQKVFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1488, "header": "tr|A0A1D5PT55-1|A0A1D5PT55_CHICK Isoform 1 of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=2 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052368.1", "url": "https://www.ensembl.org/id/ENSGALT00010052368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031295.1", "url": "https://www.ensembl.org/id/ENSGALP00010031295.1" } ] } }, { "isoform_ac": "A0A8V0ZDE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDE9/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1403, "header": "tr|A0A8V0ZDE9-1|A0A1D5PT55_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052390.1", "url": "https://www.ensembl.org/id/ENSGALT00010052390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031309.1", "url": "https://www.ensembl.org/id/ENSGALP00010031309.1" } ] } }, { "isoform_ac": "A0A8V0ZIX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX2/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1446, "header": "tr|A0A8V0ZIX2-1|A0A1D5PT55_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052386.1", "url": "https://www.ensembl.org/id/ENSGALT00010052386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031306.1", "url": "https://www.ensembl.org/id/ENSGALP00010031306.1" } ] } }, { "isoform_ac": "A0A8V0ZKG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG4/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYKVEQKVFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1436, "header": "tr|A0A8V0ZKG4-1|A0A1D5PT55_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052360.1", "url": "https://www.ensembl.org/id/ENSGALT00010052360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031288.1", "url": "https://www.ensembl.org/id/ENSGALP00010031288.1" } ] } }, { "isoform_ac": "A0A8V0ZKP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKP1/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1392, "header": "tr|A0A8V0ZKP1-1|A0A1D5PT55_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052394.1", "url": "https://www.ensembl.org/id/ENSGALT00010052394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031312.1", "url": "https://www.ensembl.org/id/ENSGALP00010031312.1" } ] } }, { "isoform_ac": "A0A8V0ZRA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA8/entry", "sequence": { "sequence": "MVSSGCRMQSFWFLLIISFLQCTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTECFLPDAYKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPYLYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNGRQQTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESETGRNAIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELYKTTASTTSTTSQKGPVSTTLAGGTKEGSRGPKPPPPISTTKIPPVTSFFPLPERFCEPTEARGISWPQTQRGMMVERPCPKGTRGTASYLCVVLTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELRPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKDMNSSEQAHAATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLDVAVLITEGQVQDLKFPQGSKGGNSIQLSASTVKQNSRNGLAKLVFIIYKSLGRFLSTENATIKLGSDFAGRNSTIAVNSHVIAASINKESSRVYLTDPVYFTLEHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTHTTCACSHLTNFAILMAHREIVYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTEYKIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNLIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFINEGTVVMTYLFTVFNAFQGMFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRNGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKNHNLERTLPAKAVIGGSSSEDDAIVADASSLMHSDTPGLELHHKELEAPLIPQRTHSLLYQPQKKVKTEGTDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDVEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMYYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1483, "header": "tr|A0A8V0ZRA8-1|A0A1D5PT55_CHICK Computationally mapped isoform of Adhesion G protein-coupled receptor L2 OS=Gallus gallus OX=9031 GN=ADGRL2 PE=3 SV=1 CANONICAL=A0A1D5PT55-1" }, "locus": { "chromosome": "8", "start_pos": 17248133, "end_pos": 17124948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052377.1", "url": "https://www.ensembl.org/id/ENSGALT00010052377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031300.1", "url": "https://www.ensembl.org/id/ENSGALP00010031300.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424545", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1NTY0-1", "protein_name": "Adhesion G protein-coupled receptor L2", "gene_name": "ADGRL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVSSGCRMRSLWFIIIISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNAIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPVTNIFPLPERFCEALDARGIRWPQTQRGMMVERPCPKGTRGTASYLCMVSTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLVEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYMIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNSARDTSAMDTLPLNGNFNNSYSLRKGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGGGKAHNLELTLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLELHHKELEAPLIPQRTHSLLYQPQKKAKPEGTDSYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYQESSPDMEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMCYQISRGNSDGYILPINKEGCIPEGDVREGQMQLVTSL", "length": 1459 }, "evidence": [ { "id": "A0A1D5PT55", "url": "https://omabrowser.org/oma/group/A0A1D5PT55/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95490-1", "protein_name": "Adhesion G protein-coupled receptor L2", "gene_name": "ADGRL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSSGCRMRSLWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLHKGDYNDSVQVVDCGLSLNDTAFEKMIISELVHNNLRGSSKTHNLELTLPVKPVIGGSSSEDDAIVADASSLMHSDNPGLELHHKELEAPLIPQRTHSLLYQPQKKVKSEGTDSYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1459 }, "evidence": [ { "id": "A0A1D5PT55", "url": "https://omabrowser.org/oma/group/A0A1D5PT55/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZZ7-1", "protein_name": "Adhesion G protein-coupled receptor L2", "gene_name": "Adgrl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSSGCRMRSLWFIIIISFSPSTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYSKMLVFVCPGTLKAIVDSPCIYEAEQKSGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETAYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNTIDYIYNTRLSRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTISTTSSASQRGPVSSTAAGPQDGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALDWKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGHVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLGLKGLGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGADLMGRNSTIAVNSPVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHHLLLTVITWVGIVVSLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTVQACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVNEETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYGKCFRHWYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPAFNSPGHSLNNARDTSAMDTLPLNGNFNNSYSLRKADYHDGVQVVDCGLSLNDTAFEKMIISELVHNNLRGGNKTHNLELKLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLEFRHKELEAPLIPQRTHSLLYQPQKKVKPEATDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYKSMPNLGAGRHLHMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL", "length": 1487 }, "evidence": [ { "id": "A0A1D5PT55", "url": "https://omabrowser.org/oma/group/A0A1D5PT55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT55", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1187, "end_pos": 1189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1284, "end_pos": 1286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PT55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 474, "end_pos": 531, "start_aa": "Phe", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PT55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 852, "end_pos": 1117, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PT55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 665, "end_pos": 842, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PT55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 399, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PT55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT55" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 130, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 1187, "end_pos": 1189 }, { "start_pos": 1260, "end_pos": 1262 }, { "start_pos": 1271, "end_pos": 1273 }, { "start_pos": 1284, "end_pos": 1286 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 749, "end_pos": 751 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 818, "end_pos": 820 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PS27-1", "uniprot_ac": "A0A1D5PS27", "uniprot_id": "A0A1D5PS27_CHICK", "mass": { "chemical_mass": 54728.0, "monoisotopic_mass": 54728.0 }, "refseq": { "ac": "NP_990285", "name": "ectonucleoside triphosphate diphosphohydrolase 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" }, "gene_names": [ { "name": "ENTPD2", "type": "recommended", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "name": "ENTPD2", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] } ], "protein_names": [ { "name": "apyrase", "type": "recommended", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.5", "type": "synonym", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27/entry#names_and_taxonomy" } ] }, { "name": "CD39 antigen-like 1", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "NTPDase 2", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "cell membrane ecto-ATPase", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "ecto-ATP diphosphohydrolase 2", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "ecto-ATPDase 2", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "ecto-ATPase 2", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] }, { "name": "ectonucleoside triphosphate diphosphohydrolase 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_990285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: U74467.1, SRR13267654.28314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Mar 18, 2015 this sequence version replaced NP_990285.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENTPD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27", "locus": { "chromosome": "17", "start_pos": 1085893, "end_pos": 1078124, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027982", "url": "https://www.ensembl.org/id/ENSGALG00010027982" } ] } } ], "crossref": [ { "id": "A0A1D5PS27", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS27", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039696", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039696", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd24111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395797", "url": "https://www.ncbi.nlm.nih.gov/gene/395797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395797", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEECRYQ", "url": "https://omabrowser.org/oma/group/NEECRYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PS27", "url": "https://www.orthodb.org/?gene=A0A1D5PS27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6M6", "url": "https://www.orthodb.org/?gene=A0A8V1A6M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8850843", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20988", "url": "https://www.rhea-db.org/rhea/20988", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23680", "url": "https://www.rhea-db.org/rhea/23680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36795", "url": "https://www.rhea-db.org/rhea/36795", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36799", "url": "https://www.rhea-db.org/rhea/36799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64876", "url": "https://www.rhea-db.org/rhea/64876", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64896", "url": "https://www.rhea-db.org/rhea/64896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64900", "url": "https://www.rhea-db.org/rhea/64900", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS27-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRAAAVLLLLALGCLLGILLLCLGSGDARGPPSFKYGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVEGPGISSYSSKPPAAGKSLEHCLSQAMRDVPKEKHADTPLYLGATAGMRLLRIADPPSSDAVLSAVMATLKSYPFDFRGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFETSDAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQAENYQETVANPCWPTGYRKSLSLSSIYDSPCTEKERPGLPLNTTVVVSGTGNGNLCAVHVNKLFDFTSCSFSHCSFDGVFQPEVSGNFIAFSAFFYTVDFIRTVMERPVHSPSDLKDAAETICATSWNELYQKAPRLEKRLPDYCATSTFVYLLITKGYNFNNRSFPSIAFQKKAGETSIGWALGYMLNLTNMIPAQEPASHRSMLYNYWVILILLFVITTLTALLTAVYLLRRSKSSTI", "length": 496, "header": "tr|A0A1D5PS27-1|A0A1D5PS27_CHICK Isoform 1 of apyrase OS=Gallus gallus OX=9031 GN=ENTPD2 PE=3 SV=1 CANONICAL=A0A1D5PS27-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PS27-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27/entry", "sequence": { "sequence": "MARRAAAVLLLLALGCLLGILLLCLGSGDARGPPSFKYGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVEGPGISSYSSKPPAAGKSLEHCLSQAMRDVPKEKHADTPLYLGATAGMRLLRIADPPSSDAVLSAVMATLKSYPFDFRGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFETSDAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQAENYQETVANPCWPTGYRKSLSLSSIYDSPCTEKERPGLPLNTTVVVSGTGNGNLCAVHVNKLFDFTSCSFSHCSFDGVFQPEVSGNFIAFSAFFYTVDFIRTVMERPVHSPSDLKDAAETICATSWNELYQKAPRLEKRLPDYCATSTFVYLLITKGYNFNNRSFPSIAFQKKAGETSIGWALGYMLNLTNMIPAQEPASHRSMLYNYWVILILLFVITTLTALLTAVYLLRRSKSSTI", "length": 496, "header": "tr|A0A1D5PS27-1|A0A1D5PS27_CHICK Isoform 1 of apyrase OS=Gallus gallus OX=9031 GN=ENTPD2 PE=3 SV=1 CANONICAL=A0A1D5PS27-1" }, "locus": { "chromosome": "17", "start_pos": 1084952, "end_pos": 1078162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067835.1", "url": "https://www.ensembl.org/id/ENSGALT00010067835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041578.1", "url": "https://www.ensembl.org/id/ENSGALP00010041578.1" } ] } }, { "isoform_ac": "A0A8V1A6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6M6/entry", "sequence": { "sequence": "PAVPRAGRERGVRGGAVLGAALLYGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVEGPGISSYSSKPPAAGKSLEHCLSQAMRDVPKEKHADTPLYLGATAGMRLLRIADPPSSDAVLSAVMATLKSYPFDFRGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFETSDAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQAENYQETVANPCWPTGYRKSLSLSSIYDSPCTEKERPGLPLNTTVVVSGTGNGNLCAVHVNKLFDFTSCSFSHCSFDGVFQPEVSGNFIAFSAFFYTVDFIRTVMERPVHSPSDLKDAAETICATSWNELYQKAPRLEKRLPDYCATSTFVYLLITKGYNFNNRSFPSIAFQKKAGETSIGWALGYMLNLTNMIPAQEPASHRSMLYNYWVILILLFVITTLTALLTAVYLLRRSKSSTI", "length": 482, "header": "tr|A0A8V1A6M6-1|A0A1D5PS27_CHICK Computationally mapped isoform of apyrase OS=Gallus gallus OX=9031 GN=ENTPD2 PE=3 SV=1 CANONICAL=A0A1D5PS27-1" }, "locus": { "chromosome": "17", "start_pos": 1084952, "end_pos": 1081367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067834.1", "url": "https://www.ensembl.org/id/ENSGALT00010067834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041577.1", "url": "https://www.ensembl.org/id/ENSGALP00010041577.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395797", "resource": "KEGG Pathway" }, { "id": "R-GGA-8850843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "resource": "Reactome", "description": "Phosphate bond hydrolysis by NTPDase proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AER5-1", "protein_name": "apyrase", "gene_name": "ENTPD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARKVLPLLLPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVSQHSSCDVHGGGISSYADNPSSAGQSLVACLDQALRDVPKERHVGTPLYLGATAGMRLLNLTSPEASANVLAAVTRTLAQYPFDCRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRSGTLGAMDLGGASTQITFETASPAEDPANEVQLRLYGHHYRVYTQSFLCYGRDQVLRRLLASALQSHGFHPCWPRGYSTHVLLQDVYESPCTAAQRPQTFNSSARVRVSGRSDPALCRGLVSELFNVSSCRFSRCSFNGVFQPPVTGSFIAFSAFFYTVEFLRTGMGLPVATLQQLEAAAVTVCNQSWSELQARAPGRQAHLPHYCAGAMFVQQLLSRGYGFDERAFGGVTFQKKAGDTAVGWALGYMLNLTNLIPADPPGLRKGADFGSWVVLLLLFAAMLLAAVVLLGLQARSSKAPSAI", "length": 495 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3MZH7-1", "protein_name": "apyrase", "gene_name": "ENTPD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGKALSLLPPLLLAAAGLAGLLLLCVPTRDIREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDAQGGGISSYADNPSGAGQSLVECLNQALRDVPKERHAGTPLYLGATAGMRLLNLTSPEASANVLAAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPTEDPANEVQLRLYGQRYRVYTHSFLCYGRDQVLRRLLARALQTHGSHPCWPRGYSTHVMLWDVYESPCTAAQRPQAFNRSTRVSLAGSSDPALCRSLVSQLFNSSSCHFSRCSFNGVFQPPVAGKFIAFSAFFYTMDFLRTVMGLPVATLQQLEGAVVTLCNQTWSELQARAPDDRARLPDYCAGAMFVQQLLSRGYGFDERSFGGVTFQKKAGDTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFAAMLLAAFALLLHQARSTKSASTI", "length": 495 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35795-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "Entpd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL", "length": 495 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55026-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "Entpd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKLVSLVPPLLLAAVGLAGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVRGGGISSYANDPSRAGQSLVECLEQALRDVPKDRYASTPLYLGATAGMRLLNLTSPEATAKVLEAVTQTLTRYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPDNEVHLRLYGQHYRVYTHSFLCYGRDQVLQRLLASALQIHRFHPCWPKGYSTQVLLREVYQSPCTMGQRPQTFNSSATVSLSGTSNAALCRDLVSGLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLKTVMGLPVGTLKQLEDATETTCNQTWAELQARVPGQQTRLPDYCAVAMFIHQLLSRGYRFDERSFRGVVFEKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL", "length": 495 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8H1D8-1", "protein_name": "Probable apyrase 4", "gene_name": "APY4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQRSNARSRSNINSDMVDPPEVQTSPGNHRSSPSTAAKPKSKRTKSIIFVIVACVTIALGLLFIGYSILRSGRNRRVSLHYSVIIDGGSSGTRVHVFGYRIESGKPVFDFGEENYASLKLSPGLSAYADNPEGVSESVTELVEFAKKRVHKGKLKKSDIRLMATAGMRLLELPVQEQILDVTRRVLRSSGFDFRDEWASVISGSDEGVYAWVVANHALGSLGGEPLKTTGIVELGGASAQVTFVSTELVPSEFSRTLAYGNVSYNLYSHSFLDFGQDAAQEKLSESLYNSAANSTGEGIVPDPCIPKGYILETNLQKDLPGFLADKGKFTATLQAAGNFSECRSAAFAMLQEEKGKCTYKRCSIGSIFTPNLQGSFLATENFFHTSKFFGLGEKEWLSEMILAGKRFCGEEWSKLKVKYPTFKDENLLRYCFSSAYIISMLHDSLGVALDDERIKYASKAGEEDIPLDWALGAFILNTATATFDYSGKSRKILDLSNVAKYKI", "length": 503 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y5L3-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "ENTPD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI", "length": 495 }, "evidence": [ { "id": "A0A1D5PS27", "url": "https://omabrowser.org/oma/group/A0A1D5PS27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "apyrase activity", "id": "GO:0004050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004050", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribonucleoside triphosphate catabolic process", "id": "GO:0009203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009203", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS27", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "20988", "name": "", "equation": "ATP + 2 H2O = AMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "20988", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20988" } ] }, { "id": "23680", "name": "", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "F1P5C0-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "36795", "name": "", "equation": "a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O93295-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V0ZNW3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1" ], "evidence": [ { "id": "36795", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36795" } ] }, { "id": "36799", "name": "", "equation": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "A0A8V1AMW1-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "36799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36799" } ] }, { "id": "64876", "name": "", "equation": "UDP + H2O = UMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64876" } ] }, { "id": "64896", "name": "", "equation": "UTP + 2 H2O = UMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64896" } ] }, { "id": "64900", "name": "", "equation": "UTP + H2O = UDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "A0A8V0Z5P2-1", "A0A8V1ADZ7-1", "Q5ZM73-1", "Q5ZM83-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64900" } ] }, { "id": "R-GGA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PS27-1" ], "evidence": [ { "id": "R-GGA-8851089", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851089" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XQY2", "gene_name": "", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": 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}, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": 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"3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + 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"ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] } ] }, { "uniprot_ac": "Q5ZIW1", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] } ] }, { "uniprot_ac": "Q5ZJ54", "gene_name": "CCT6", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ54" } ] } ] }, { "uniprot_ac": "Q5ZJF6", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZM36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM36" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZM36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM36" } ] } ] }, { "uniprot_ac": "Q5ZM73", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5ZM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM73" } ] } ] }, { "uniprot_ac": "Q5ZM83", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5ZM83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM83" } ] } ] }, { "uniprot_ac": "Q5ZM98", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM98" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q5ZM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM98" } ] } ] }, { "uniprot_ac": "Q5ZMN2", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMN2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q5ZMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMN2" } ] } ] }, { "uniprot_ac": "Q5ZMQ2", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q5ZMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ2" } ] } ] }, { "uniprot_ac": "Q6EE31", "gene_name": "CCT8", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q6EE31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6EE31" } ] } ] }, { "uniprot_ac": "Q8JFP1", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q8JFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JFP1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q8JFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JFP1" } ] } ] }, { "uniprot_ac": "Q90593", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q90593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90593" } ] } ] }, { "uniprot_ac": "Q90WU3", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q90WU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WU3" } ] } ] }, { "uniprot_ac": "Q92058", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q92058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92058" } ] } ] }, { "uniprot_ac": "Q9DG67", "gene_name": "RAD54B", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q9DG67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DG67" } ] } ] }, { "uniprot_ac": "Q9I920", "gene_name": "BLM", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q9I920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I920" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PS27-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 496, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PS27-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS27" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.5", "ec_name": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "3.6.1.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5" }, { "id": "3.6.1.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.5" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PVS9-1", "uniprot_ac": "A0A1D5PVS9", "uniprot_id": "A0A1D5PVS9_CHICK", "mass": { "chemical_mass": 57834.0, "monoisotopic_mass": 57834.0 }, "refseq": { "ac": "NP_001308493", "name": "ectonucleoside triphosphate diphosphohydrolase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308493" }, "gene_names": [ { "name": "ENTPD3", "type": "recommended", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "name": "ENTPD3", "type": "synonym", "evidence": [ { "id": "NP_001308493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308493" } ] } ], "protein_names": [ { "name": "apyrase", "type": "recommended", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.5", "type": "synonym", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9/entry#names_and_taxonomy" } ] }, { "name": "ectonucleoside triphosphate diphosphohydrolase 3", "type": "synonym", "evidence": [ { "id": "NP_001308493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308493" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.73812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000037.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001308493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308493" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENTPD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9", "locus": { "chromosome": "2", "start_pos": 41091128, "end_pos": 41111314, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016808", "url": "https://www.ensembl.org/id/ENSGALG00010016808" } ] } } ], "crossref": [ { "id": "A0A1D5PVS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030493", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd24112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428447", "url": "https://www.ncbi.nlm.nih.gov/gene/428447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PVS9", "url": "https://www.orthodb.org/?gene=A0A1D5PVS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR95", "url": "https://www.orthodb.org/?gene=A0A8V0YR95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11782:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11782:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8850843", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001308493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20988", "url": "https://www.rhea-db.org/rhea/20988", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23680", "url": "https://www.rhea-db.org/rhea/23680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36795", "url": "https://www.rhea-db.org/rhea/36795", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36799", "url": "https://www.rhea-db.org/rhea/36799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64876", "url": "https://www.rhea-db.org/rhea/64876", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64896", "url": "https://www.rhea-db.org/rhea/64896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64900", "url": "https://www.rhea-db.org/rhea/64900", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTRTPSVVAQAFLLLSVILIIAIAVIQINQQKILSPGLKYGIVLDAGSSRTTVYVYEWPAEKENDTGVVSQTFKCDVKGPGISSYEHNTGALAKPLDECLNKVKERIPVHLHKSTSLYLGATAGMRLLRLQNETAANEVLASIQNYFRAQPFQFRGAHIITGPEEGVYGWITANYLMGNFLERNLWRAWVHPYRRETMGALDLGGASTQISFIPEDSQENFNNTMQVKLYGYDYNVYTHSFQCYGRDEAEKRLLALLLQKSSTNSSVDNPCYPRNYKTALTVKYFCGSLCTQSLRPTNYYPDQSVIYHGTGDPGLCQEMVSLLFNFSTCRSQEDCPFNGIHQPKVKGNFVAFSGFYYTINALNLTGHFTLTDFNSSMWFFCSQSWAQLQFMLPKSEEIYARSYCFSANFIYYLLVRGYNFDAGNWPQIHFQKEVGNSSIAWSLGYMLSLTNMIPAEGKLIQLPLKPSLFAGLLIFLTVLALLCLFFLVYLCIVSRNQKVISRVEYVFTPE", "length": 511, "header": "tr|A0A1D5PVS9-1|A0A1D5PVS9_CHICK Isoform 1 of apyrase OS=Gallus gallus OX=9031 GN=ENTPD3 PE=3 SV=1 CANONICAL=A0A1D5PVS9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9/entry", "sequence": { "sequence": "MLTRTPSVVAQAFLLLSVILIIAIAVIQINQQKILSPGLKYGIVLDAGSSRTTVYVYEWPAEKENDTGVVSQTFKCDVKGPGISSYEHNTGALAKPLDECLNKVKERIPVHLHKSTSLYLGATAGMRLLRLQNETAANEVLASIQNYFRAQPFQFRGAHIITGPEEGVYGWITANYLMGNFLERNLWRAWVHPYRRETMGALDLGGASTQISFIPEDSQENFNNTMQVKLYGYDYNVYTHSFQCYGRDEAEKRLLALLLQKSSTNSSVDNPCYPRNYKTALTVKYFCGSLCTQSLRPTNYYPDQSVIYHGTGDPGLCQEMVSLLFNFSTCRSQEDCPFNGIHQPKVKGNFVAFSGFYYTINALNLTGHFTLTDFNSSMWFFCSQSWAQLQFMLPKSEEIYARSYCFSANFIYYLLVRGYNFDAGNWPQIHFQKEVGNSSIAWSLGYMLSLTNMIPAEGKLIQLPLKPSLFAGLLIFLTVLALLCLFFLVYLCIVSRNQKVISRVEYVFTPE", "length": 511, "header": "tr|A0A1D5PVS9-1|A0A1D5PVS9_CHICK Isoform 1 of apyrase OS=Gallus gallus OX=9031 GN=ENTPD3 PE=3 SV=1 CANONICAL=A0A1D5PVS9-1" }, "locus": { "chromosome": "2", "start_pos": 41109158, "end_pos": 41093573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040561.1", "url": "https://www.ensembl.org/id/ENSGALT00010040561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023549.1", "url": "https://www.ensembl.org/id/ENSGALP00010023549.1" } ] } }, { "isoform_ac": "A0A8V0YR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR95/entry", "sequence": { "sequence": "MLTRTPSVVAQAFLLLSVILIIAIAVIQINQQKILSPGLKYGIVLDAGSSRTTVYVYEWPAEKENDTGVVSQTFKCDVKGPGISSYEHNTGALAKPLDECLNKVKERIPVHLHKSTSLYLGATAGMRLLRLQNETAANEVLASIQNYFRAQPFQFRGAHIITGPEEGVYGWITANYLMGNFLERNLWRAWVHPYRRETMGALDLGGASTQISFIPEDSQENFNNTMQVKLYGYDYNVYTHSFQCYGRDEAEKRLLALLLQKSSTNSSVDNPCYPRNYKTALTVKYFCGSLCTQSLRPTNYYPDQSVIYHGTGDPGLCQEMVSLLFNFSTCRSQEDCPFNGIHQPKVKGNFVAFSGFYYTINALNLTGHFTLTDFNSSMWFFCSQSWAQLQFMLPKSEEIYARSYCFSANFIYYLLVRGYNFDAGNWPQIHFQKEVGAAKPGSIFLYLAKTIKVLSKMETQKAYLLPTVCTRVIVKVQKKDDILLIRSAPQRTKTSHI", "length": 497, "header": "tr|A0A8V0YR95-1|A0A1D5PVS9_CHICK Computationally mapped isoform of apyrase OS=Gallus gallus OX=9031 GN=ENTPD3 PE=3 SV=1 CANONICAL=A0A1D5PVS9-1" }, "locus": { "chromosome": "2", "start_pos": 41109158, "end_pos": 41094569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040554.1", "url": "https://www.ensembl.org/id/ENSGALT00010040554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023544.1", "url": "https://www.ensembl.org/id/ENSGALP00010023544.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:428447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428447", "resource": "KEGG Pathway" }, { "id": "R-GGA-8850843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8850843", "resource": "Reactome", "description": "Phosphate bond hydrolysis by NTPDase proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "apyrase activity", "id": "GO:0004050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004050", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ribonucleoside triphosphate catabolic process", "id": "GO:0009203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009203", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "ribonucleoside diphosphate catabolic process", "id": "GO:0009191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009191", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "20988", "name": "", "equation": "ATP + 2 H2O = AMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "20988", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20988" } ] }, { "id": "23680", "name": "", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "F1P5C0-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "36795", "name": "", "equation": "a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O93295-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V0ZNW3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1" ], "evidence": [ { "id": "36795", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36795" } ] }, { "id": "36799", "name": "", "equation": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "A0A8V1AMW1-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "36799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36799" } ] }, { "id": "64876", "name": "", "equation": "UDP + H2O = UMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64876" } ] }, { "id": "64896", "name": "", "equation": "UTP + 2 H2O = UMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64896" } ] }, { "id": "64900", "name": "", "equation": "UTP + H2O = UDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "A0A8V0Z5P2-1", "A0A8V1ADZ7-1", "Q5ZM73-1", "Q5ZM83-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "64900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64900" } ] }, { "id": "R-GGA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PVS9-1" ], "evidence": [ { "id": "R-GGA-8851110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851110" } ] }, { "id": "R-GGA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PVS9-1" ], "evidence": [ { "id": "R-GGA-8851129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8851129" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XQY2", "gene_name": "", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFD3-1", "uniprot_ac": "A0A1D5PFD3", "uniprot_id": "A0A1D5PFD3_CHICK", "mass": { "chemical_mass": 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"NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" }, { "id": "A0A1D5PFD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3/entry#names_and_taxonomy" } ] }, { "name": "cancer susceptibility 4", "type": "synonym", "evidence": [ { "id": "NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] }, { "name": "cancer susceptibility candidate gene 4 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] }, { "name": "protein CASC4", "type": "synonym", "evidence": [ { "id": "NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] }, { "name": "protein GOLM2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] }, { "name": "protein GOLM2", "type": "synonym", "evidence": [ { "id": "NP_001376302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.27849.1, SRR13267655.189802.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000246.1. On Dec 17, 2020 this sequence version replaced XP_015147602.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3", "locus": { "chromosome": "10", "start_pos": 19839930, "end_pos": 19865320, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016350", "url": "https://www.ensembl.org/id/ENSGALG00010016350" } ] } } ], "crossref": [ { "id": "A0A1D5PFD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008208", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415575", "url": "https://www.ncbi.nlm.nih.gov/gene/415575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XRFFDEN", "url": "https://omabrowser.org/oma/group/XRFFDEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFD3", "url": "https://www.orthodb.org/?gene=A0A1D5PFD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVD6", "url": "https://www.orthodb.org/?gene=A0A8V0YVD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVR4", "url": "https://www.orthodb.org/?gene=A0A8V0YVR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z264", "url": "https://www.orthodb.org/?gene=A0A8V0Z264", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15896:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15896:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001376302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z264", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z264", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z264-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z264-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQSRFFDENESPVDPQQGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERDLQNDLVDYSKPRFGDGVL", "length": 439, "header": "tr|A0A1D5PFD3-1|A0A1D5PFD3_CHICK Isoform 1 of Protein GOLM2 OS=Gallus gallus OX=9031 GN=CASC4 PE=3 SV=1 CANONICAL=A0A1D5PFD3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3/entry", "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQSRFFDENESPVDPQQGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERDLQNDLVDYSKPRFGDGVL", "length": 439, "header": "tr|A0A1D5PFD3-1|A0A1D5PFD3_CHICK Isoform 1 of Protein GOLM2 OS=Gallus gallus OX=9031 GN=CASC4 PE=3 SV=1 CANONICAL=A0A1D5PFD3-1" }, "locus": { "chromosome": "10", "start_pos": 19865156, "end_pos": 19846240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039363.1", "url": "https://www.ensembl.org/id/ENSGALT00010039363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022708.1", "url": "https://www.ensembl.org/id/ENSGALP00010022708.1" } ] } }, { "isoform_ac": "A0A8V0YVD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVD6/entry", "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQRKRPKEVMKM", "length": 369, "header": "tr|A0A8V0YVD6-1|A0A1D5PFD3_CHICK Computationally mapped isoform of Protein GOLM2 OS=Gallus gallus OX=9031 GN=CASC4 PE=3 SV=1 CANONICAL=A0A1D5PFD3-1" }, "locus": { "chromosome": "10", "start_pos": 19865156, "end_pos": 19842874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039375.1", "url": "https://www.ensembl.org/id/ENSGALT00010039375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022712.1", "url": "https://www.ensembl.org/id/ENSGALP00010022712.1" } ] } }, { "isoform_ac": "A0A8V0YVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR4/entry", "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQKGQGSNSHNGCQE", "length": 372, "header": "tr|A0A8V0YVR4-1|A0A1D5PFD3_CHICK Computationally mapped isoform of Protein GOLM2 OS=Gallus gallus OX=9031 GN=CASC4 PE=3 SV=1 CANONICAL=A0A1D5PFD3-1" }, "locus": { "chromosome": "10", "start_pos": 19865156, "end_pos": 19840934, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039379.1", "url": "https://www.ensembl.org/id/ENSGALT00010039379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022714.1", "url": "https://www.ensembl.org/id/ENSGALP00010022714.1" } ] } }, { "isoform_ac": "A0A8V0Z264-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z264/entry", "sequence": { "sequence": "MVGFGANRRGGRLPSFLLAALLLVIAVLAFNCWNAASRQAVLREELAELQSQAKRTEVARGRLEKRNSDLLGRVDSHRKQLEQKEADYSQLSSQLQARDGQVKRCEDSRVKLQNNISYQMADIHRLKEQLAELRQEFIRQEDQLHEYKKNNTYLTRRLEYDSLQCGQQIKEMRIQHEENIKKLMDQIVREQKATQRIQSSKDAEVNPNGDNQPISKTVPEMEVKNAENNELPSDRVVNGKEKVKPGGDAGMPEIEDNDPAKAEDTPTAIKKPLISAPRSDNHHQADVNLPTEQPHAPNLAPGLHGDNDGNADIAKEIPPNSLQHLNFGENMDSQNENKIEADHLKLQKGRAVGLQKMKQNDEERDLQNDLVDYSKPRFGDGVL", "length": 383, "header": "tr|A0A8V0Z264-1|A0A1D5PFD3_CHICK Computationally mapped isoform of Protein GOLM2 OS=Gallus gallus OX=9031 GN=CASC4 PE=3 SV=1 CANONICAL=A0A1D5PFD3-1" }, "locus": { "chromosome": "10", "start_pos": 19865156, "end_pos": 19846240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039371.1", "url": "https://www.ensembl.org/id/ENSGALT00010039371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022711.1", "url": "https://www.ensembl.org/id/ENSGALP00010022711.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R207-1", "protein_name": "Protein GOLM2", "gene_name": "GOLM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIRHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQETHKFESKNRNELDINNHAVPRNIPKVEENAADKNKEPSSNHNPHGKEQIKGGGDAGMPEIEENDVAKAEDLPTGLKKPPLSFSQYESHQTISHLPTGQPLSPNIVQDSHVNHNGNPRTSKQNPSNPLQRIIPGPNLENEPRIQADILKQATKDRAGDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFNDVL", "length": 436 }, "evidence": [ { "id": "A0A1D5PFD3", "url": "https://omabrowser.org/oma/group/A0A1D5PFD3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2VE10-1", "protein_name": "Protein GOLM2", "gene_name": "GOLM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGFGANRRAGRLPSLVLAVLLVVIAVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDSHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKQEAHKFESKGGNELDTDNHAVPKNIPEVAENGAGKNEEPSSHHIPHGKEQIKRGGDAGMPGIEENDLAKAEDVPVALKKPPVSFSQYESHQVISHLPTGQPLSPNMVPDSHINHNGNSRTSKQNPSNPLQRLIPGPNLENEPRIQAEVLKQATKDRAGDFHKLKQNDEERELQMDPADYGKQRFNDAL", "length": 380 }, "evidence": [ { "id": "A0A1D5PFD3", "url": "https://omabrowser.org/oma/group/A0A1D5PFD3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FBP9-1", "protein_name": "Protein GOLM2", "gene_name": "golm2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIGFGAIRRGGRLPSFILIALLVVIVILSFNYWSVSTKHARLLDELAEVQTQVKRTDAARSRLEKRNSELMMQVDTHRKQIDLKDGDYSALQNKLQARDALVKTCTDDKNKLQNDVSAQMSEIHRLKEQVKELRQEVIRQEDQQREVRKNSTNLEKKLEYESLQCGRQIAELKAEYEESKKRVEEEAAKLRQSLLENRNADSVVQHVDLDLDQSNKRKEKEDTAERHTVAARRNDVPVLKDDLGKPGSDAGMPGIEDSEVGKIDDSQFAIKKPAITPQKHMEPAEAAAMLKEERAGFGAGAGARLGDDLARGQPLDRPDMPRDENLRLMNRDIPVQQQVPQPVVIKPMLFDEDNKAGIKADEFGEQRRQVGAEGLKAEGVGIPPPPNPVQVHAKPIDPHNGRDPVAADPPRHRQSRFFDENESPVDPQHGNKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEDRDAPGERNVDYGKRHQANDVL", "length": 495 }, "evidence": [ { "id": "A0A1D5PFD3", "url": "https://omabrowser.org/oma/group/A0A1D5PFD3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P2L7-1", "protein_name": "Protein GOLM2", "gene_name": "Golm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGFGANRRAGRLPSFVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAKEGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQIKELRAQHEENIKKLADQFLQEQKETHKIQSNDGKELGRNDHGAPKNIPNVPENDANKNEDPSSNHLPHGKEQLKRVGDAGMPGVEENDLAKVDELPAALKKPPVLASQHESHQTISHLPTGQPLSPNMAPGSHLNQNENPSTSKQNPSNPLQHIIPGPNLDREPRIQTDTLKQATRDRANDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQRFSDVL", "length": 435 }, "evidence": [ { "id": "A0A1D5PFD3", "url": "https://omabrowser.org/oma/group/A0A1D5PFD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P4E1-4", "protein_name": "Protein GOLM2", "gene_name": "GOLM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEERELQMDPADYGKQHFNDVL", "length": 436 }, "evidence": [ { "id": "A0A1D5PFD3", "url": "https://omabrowser.org/oma/group/A0A1D5PFD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PFD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFD3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 366, "end_pos": 368 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PX32-1", "uniprot_ac": "A0A1D5PX32", "uniprot_id": "A0A1D5PX32_CHICK", "mass": { "chemical_mass": 28751.0, "monoisotopic_mass": 28751.0 }, "refseq": { "ac": "XP_003640982", "name": "serine/arginine-rich splicing factor 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640982" }, "gene_names": [ { "name": "SRSF7", "type": "recommended", "evidence": [ { "id": "A0A1D5PX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ] }, { "name": "SRSF7", "type": "synonym", "evidence": [ { "id": "XP_003640982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640982" } ] } ], "protein_names": [ { "name": "Serine/arginine-rich splicing factor 7", "type": "recommended", "evidence": [ { "id": "A0A1D5PX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 7", "type": "synonym", "evidence": [ { "id": "A0A1D5PX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32/entry#names_and_taxonomy" } ] }, { "name": "serine/arginine-rich splicing factor 7", "type": "synonym", "evidence": [ { "id": "XP_003640982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_003640982.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRSF7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32", "locus": {} } ], "crossref": [ { "id": "A0A1D5PX32", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PX32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038528", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12646", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12646", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859609", "url": "https://www.ncbi.nlm.nih.gov/gene/100859609", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859609", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859609", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGPLNCK", "url": "https://omabrowser.org/oma/group/HGPLNCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PX32", "url": "https://www.orthodb.org/?gene=A0A1D5PX32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZR3", "url": "https://www.orthodb.org/?gene=A0A8V0YZR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z142", "url": "https://www.orthodb.org/?gene=A0A8V0Z142", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z146", "url": "https://www.orthodb.org/?gene=A0A8V0Z146", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003640982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PX32-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z142", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z142", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z142-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z142-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z146", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z146-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z146-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVEVSTGMPRRSRYDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSRSRSRGRRYSRSRSRSRGRRSRSASYRRSRSVSPRRSRSVSPRRSRSGSLKRSRSRSRSRSRSRSVTWPRSRSRSHGRSKSGTPAKSRSKSRSPSPKRSRSPSGSPQRSASPERMD", "length": 250, "header": "tr|A0A1D5PX32-1|A0A1D5PX32_CHICK Isoform 1 of Serine/arginine-rich splicing factor 7 OS=Gallus gallus OX=9031 GN=SRSF7 PE=1 SV=2 CANONICAL=A0A1D5PX32-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PX32-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32/entry", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVEVSTGMPRRSRYDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSRSRSRGRRYSRSRSRSRGRRSRSASYRRSRSVSPRRSRSVSPRRSRSGSLKRSRSRSRSRSRSRSVTWPRSRSRSHGRSKSGTPAKSRSKSRSPSPKRSRSPSGSPQRSASPERMD", "length": 250, "header": "tr|A0A1D5PX32-1|A0A1D5PX32_CHICK Isoform 1 of Serine/arginine-rich splicing factor 7 OS=Gallus gallus OX=9031 GN=SRSF7 PE=1 SV=2 CANONICAL=A0A1D5PX32-1" }, "locus": { "chromosome": "3", "start_pos": 16231063, "end_pos": 16224720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041264.1", "url": "https://www.ensembl.org/id/ENSGALT00010041264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024157.1", "url": "https://www.ensembl.org/id/ENSGALP00010024157.1" } ] } }, { "isoform_ac": "A0A8V0YZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZR3/entry", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVEVSTGMPRRSRYDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSRSRSRGRRYSRSRSRSRGRRSRSASYRRSRSVSPRRSRSGSLKRSRSRSRSRSRSRSVTWPRSRSRSHGRSKSGTPAKSRSKSRSPSPKRSRSPSGSPQRSASPERMD", "length": 242, "header": "tr|A0A8V0YZR3-1|A0A1D5PX32_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 7 OS=Gallus gallus OX=9031 GN=SRSF7 PE=1 SV=1 CANONICAL=A0A1D5PX32-1" }, "locus": { "chromosome": "3", "start_pos": 16231063, "end_pos": 16224720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041259.1", "url": "https://www.ensembl.org/id/ENSGALT00010041259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024154.1", "url": "https://www.ensembl.org/id/ENSGALP00010024154.1" } ] } }, { "isoform_ac": "A0A8V0Z142-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z142/entry", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVEVSTGMPRRSRYDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRFLRLSQSP", "length": 137, "header": "tr|A0A8V0Z142-1|A0A1D5PX32_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 7 OS=Gallus gallus OX=9031 GN=SRSF7 PE=1 SV=1 CANONICAL=A0A1D5PX32-1" }, "locus": { "chromosome": "3", "start_pos": 16231063, "end_pos": 16230026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041244.1", "url": "https://www.ensembl.org/id/ENSGALT00010041244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024143.1", "url": "https://www.ensembl.org/id/ENSGALP00010024143.1" } ] } }, { "isoform_ac": "A0A8V0Z146-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z146/entry", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVEVSTGMPRRSRYDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSRSRSRGRRYSRSRSRSRGRRSRSASYRRSRSVSPRRSRSVSPRRSRSGSLKRSRSRSRSRSRSRSVTWPRSRSRSHGRSKSGTPAKSRSKSRSPSPKRSRSPSGSPQRSASPERMD", "length": 238, "header": "tr|A0A8V0Z146-1|A0A1D5PX32_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 7 OS=Gallus gallus OX=9031 GN=SRSF7 PE=1 SV=1 CANONICAL=A0A1D5PX32-1" }, "locus": { "chromosome": "3", "start_pos": 16231063, "end_pos": 16224720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041251.1", "url": "https://www.ensembl.org/id/ENSGALT00010041251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024148.1", "url": "https://www.ensembl.org/id/ENSGALP00010024148.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859609", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859609", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ASZ5-1", "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "SRSF7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSVSLRRSRSASLRRSRSGSIKGSRYFQSRSRSRSRSRSLSRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERVD", "length": 238 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AFZ5-1", "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "Srsf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSVSLRRSRSASLRRSRSGSIIGSRYFQSRSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPHRSASPERMD", "length": 238 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O81126-1", "protein_name": "Serine/arginine-rich splicing factor RSZ22", "gene_name": "RSZ22", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSRVYVGNLDPRVTERELEDEFRAFGVVRSVWVARRPPGYAFLDFEDPRDARDAIRALDGKNGWRVEQSHNRGERGGGGRGGDRGGGGGGRGGRGGSDLKCYECGETGHFARECRNRGGTGRRRSKSRSRTPPRYRRSPSYGRRSYSPRARSPPPPRRRSPSPPPARGRSYSRSPPPYRAREEVPYANGNGLKERRRSRS", "length": 200 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q16629-1", "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "SRSF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD", "length": 238 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3T106-1", "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "SRSF7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSVSLRRSRSASLRRSRSGSIKGSRSRSRSRSRSRSLSRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERVD", "length": 235 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BL97-1", "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "Srsf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSSARGRPLQAATAFFLSLFFFLRRFERGFWLWGGDSETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSVSLRRSRSASLRRSRSGSIIGSRYFQSRSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPHRSASPERMD", "length": 267 }, "evidence": [ { "id": "A0A1D5PX32", "url": "https://omabrowser.org/oma/group/A0A1D5PX32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PX32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PX32-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 250, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PX32-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PX32" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P948-1", "uniprot_ac": "A0A1D5P948", "uniprot_id": "A0A1D5P948_CHICK", "mass": { "chemical_mass": 61784.0, "monoisotopic_mass": 61784.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Mab-21-like HhH/H2TH-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P948", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948", "locus": {} } ], "crossref": [ { "id": "A0A1D5P948", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P948", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030245", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P948", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P948-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPVLKAILPGWKAKAPLAIKIMALAFVFSLLAQRVPCVGDYLDEETLNRMRQREVYLQEQMTKLLLEIEEMEVARSRMGMQALLFALLPYWKIFNFLCLFILLFWFMWKIHREFQRVEDSSDEESSSSEEEQQQEQQEEQQEQQEEQQQQEEGVEEEQPFFLPGALWSIQSPQVNTEHTLLLLSELIAISQYLVSDTFYPVPQHPIGVGGAYEGWYPVEHEPVLCVLVPLLAPRGHVFHPDLSTIGELPAKNSRIHVALECTCGREQEMGMQCFLHASAEELRNQQPSLLHNLCTDSCLDVEKTARWFLVLIRNAWKCIPASATCSMNVVLSRRSCRLRVRNIFRSTSIKLVFGVQQDNTDIFLSSQETDYQEPGGTPSTIWPQSCAVAEAKFFQHVASHAEDDHFHFRCMQVCAYILSGHNFSTYELKTVFMHLLNAIPLENWHERYFLLQMDDIFRYLRCCVEEKRLNHFLIGNEDVPAEIILPQDFRESEPLNLFQHLAQDPDKHEQALQELERLEDRLTSMLIYGK", "length": 532, "header": "tr|A0A1D5P948-1|A0A1D5P948_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A1D5P948-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P948-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948/entry", "sequence": { "sequence": "MLLPVLKAILPGWKAKAPLAIKIMALAFVFSLLAQRVPCVGDYLDEETLNRMRQREVYLQEQMTKLLLEIEEMEVARSRMGMQALLFALLPYWKIFNFLCLFILLFWFMWKIHREFQRVEDSSDEESSSSEEEQQQEQQEEQQEQQEEQQQQEEGVEEEQPFFLPGALWSIQSPQVNTEHTLLLLSELIAISQYLVSDTFYPVPQHPIGVGGAYEGWYPVEHEPVLCVLVPLLAPRGHVFHPDLSTIGELPAKNSRIHVALECTCGREQEMGMQCFLHASAEELRNQQPSLLHNLCTDSCLDVEKTARWFLVLIRNAWKCIPASATCSMNVVLSRRSCRLRVRNIFRSTSIKLVFGVQQDNTDIFLSSQETDYQEPGGTPSTIWPQSCAVAEAKFFQHVASHAEDDHFHFRCMQVCAYILSGHNFSTYELKTVFMHLLNAIPLENWHERYFLLQMDDIFRYLRCCVEEKRLNHFLIGNEDVPAEIILPQDFRESEPLNLFQHLAQDPDKHEQALQELERLEDRLTSMLIYGK", "length": 532, "header": "tr|A0A1D5P948-1|A0A1D5P948_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A1D5P948-1" }, "locus": { "chromosome": "5", "start_pos": 54065083, "end_pos": 54062406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040855.1", "url": "https://www.ensembl.org/id/ENSGALT00010040855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023819.1", "url": "https://www.ensembl.org/id/ENSGALP00010023819.1" } ] } }, { "isoform_ac": "A0A8V0Z5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q5/entry", "sequence": { "sequence": "MALAFVFSLLAQRVPCVGDYLDEETLNRMRQREVYLQEQMTKLLLEIEEMEVARSRMGMQALLFALLPYWKIFNFLCLFILLFWFMWKIHREFQRVEDSSDEESSSSEEEQQQEQQEEQQEQQEEQQQQEEGVEEEQPFFLPGALWSIQSPQVNTEHTLLLLSELIAISQYLVSDTFYPVPQHPIGVGGAYEGWYPVEHEPVLCVLVPLLAPRGHVFHPDLSTIGELPAKNSRIHVALECTCGREQEMGMQCFLHASAEELRNQQPSLLHNLCTDSCLDVEKTARWFLVLIRNAWKCIPASATCSMNVVLSRRSCRLRVRNIFRSTSIKLVFGVQQDNTDIFLSSQETDYQEPGGTPSTIWPQSCAVAEAKFFQHVASHAEDDHFHFRCMQVCAYILSGHNFSTYELKTVFMHLLNAIPLENWHERYFLLQMDDIFRYLRCCVEEKRLNHFLIGNEDVPAEIILPQDFRESEPLNLFQHLAQDPDKHEQALQELERLEDRLTSMLIYGK", "length": 509, "header": "tr|A0A8V0Z5Q5-1|A0A1D5P948_CHICK Computationally mapped isoform of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A1D5P948-1" }, "locus": { "chromosome": "5", "start_pos": 54069671, "end_pos": 54068932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040871.1", "url": "https://www.ensembl.org/id/ENSGALT00010040871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023835.1", "url": "https://www.ensembl.org/id/ENSGALP00010023835.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 379, "start_aa": "Thr", "end_pos": 379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr379", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P948", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P948-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 532, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P948-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P948" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P948" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 477, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 379 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 424, "end_pos": 426 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PKG8-1", "uniprot_ac": "A0A1D5PKG8", "uniprot_id": "A0A1D5PKG8_CHICK", "mass": { "chemical_mass": 54728.0, "monoisotopic_mass": 54728.0 }, "refseq": { "ac": "XP_426048", "name": "F-box/LRR-repeat protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426048" }, "gene_names": [ { "name": "FBXL7", "type": "recommended", "evidence": [ { "id": "A0A1D5PKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ] }, { "name": "FBXL7", "type": "synonym", "evidence": [ { "id": "XP_426048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426048" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 7", "type": "recommended", "evidence": [ { "id": "A0A1D5PKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 7", "type": "synonym", "evidence": [ { "id": "A0A1D5PKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426048" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_426048.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426048" } ] }, { "annotation": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest. It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8#function" }, { "database": "UniProtKB", "id": "ARBA00058860", "url": "https://www.uniprot.org/uniprotkb/ARBA00058860#function" }, { "database": "UniProtKB", "id": "A0A8V0X3M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M5#function" }, { "database": "UniProtKB", "id": "A0A8V0X3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M8#function" }, { "database": "UniProtKB", "id": "A0A8V0X625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X625#function" }, { "database": "UniProtKB", "id": "A0A8V0X630", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X630#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8", "locus": { "chromosome": "2", "start_pos": 75481259, "end_pos": 75810987, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000714", "url": "https://www.ensembl.org/id/ENSGALG00010000714" } ] } } ], "crossref": [ { "id": "A0A1D5PKG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PKG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031947", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031947", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22120", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22120", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428492", "url": "https://www.ncbi.nlm.nih.gov/gene/428492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETVHVDR", "url": "https://omabrowser.org/oma/group/ETVHVDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKG8", "url": "https://www.orthodb.org/?gene=A0A1D5PKG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X3M5", "url": "https://www.orthodb.org/?gene=A0A8V0X3M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X3M8", "url": "https://www.orthodb.org/?gene=A0A8V0X3M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X625", "url": "https://www.orthodb.org/?gene=A0A8V0X625", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X630", "url": "https://www.orthodb.org/?gene=A0A8V0X630", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8854050", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854050", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_426048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426048", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X625", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X625-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X625-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X630", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X630", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X630-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X630-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGASNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 491, "header": "tr|A0A1D5PKG8-1|A0A1D5PKG8_CHICK Isoform 1 of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=2 CANONICAL=A0A1D5PKG8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8/entry", "sequence": { "sequence": "MGASNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 491, "header": "tr|A0A1D5PKG8-1|A0A1D5PKG8_CHICK Isoform 1 of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=2 CANONICAL=A0A1D5PKG8-1" }, "locus": { "chromosome": "2", "start_pos": 75650960, "end_pos": 75483606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001528.1", "url": "https://www.ensembl.org/id/ENSGALT00010001528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000834.1", "url": "https://www.ensembl.org/id/ENSGALP00010000834.1" } ] } }, { "isoform_ac": "A0A8V0X3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M5/entry", "sequence": { "sequence": "MISKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 481, "header": "tr|A0A8V0X3M5-1|A0A1D5PKG8_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=1 CANONICAL=A0A1D5PKG8-1" }, "locus": { "chromosome": "2", "start_pos": 75628677, "end_pos": 75483606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001524.1", "url": "https://www.ensembl.org/id/ENSGALT00010001524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000830.1", "url": "https://www.ensembl.org/id/ENSGALP00010000830.1" } ] } }, { "isoform_ac": "A0A8V0X3M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M8/entry", "sequence": { "sequence": "MEEARYSLIDLWERKHLVQVQPLCLHVLQLHSLDNTTSLSKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 518, "header": "tr|A0A8V0X3M8-1|A0A1D5PKG8_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=1 CANONICAL=A0A1D5PKG8-1" }, "locus": { "chromosome": "2", "start_pos": 75725967, "end_pos": 75483606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001529.1", "url": "https://www.ensembl.org/id/ENSGALT00010001529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000835.1", "url": "https://www.ensembl.org/id/ENSGALP00010000835.1" } ] } }, { "isoform_ac": "A0A8V0X625-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X625/entry", "sequence": { "sequence": "MMQGKNQKELAGKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 490, "header": "tr|A0A8V0X625-1|A0A1D5PKG8_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=1 CANONICAL=A0A1D5PKG8-1" }, "locus": { "chromosome": "2", "start_pos": 75624709, "end_pos": 75483606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001522.1", "url": "https://www.ensembl.org/id/ENSGALT00010001522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000828.1", "url": "https://www.ensembl.org/id/ENSGALP00010000828.1" } ] } }, { "isoform_ac": "A0A8V0X630-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X630/entry", "sequence": { "sequence": "MYCSMCSSRDGGRHLSLAELLWCCHLVHCLLIRELGFQRETGKGSSSISSDVSSSTDHTPTKAQKNAATSEDSDLSMRTLSTPSPALIFPPTSPGFQNGRGSSTSSSSVTGETVAMVHSPPPTRLTHPLIRLAAKQQKEQAHVDRLPDQSMIHIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRITDEGLRYLMIYCTSIKELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCGRITDVGIRYIAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCDVSVDALRFVKRHCKRCIIEHTNPAFF", "length": 520, "header": "tr|A0A8V0X630-1|A0A1D5PKG8_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 7 OS=Gallus gallus OX=9031 GN=FBXL7 PE=3 SV=1 CANONICAL=A0A1D5PKG8-1" }, "locus": { "chromosome": "2", "start_pos": 75649747, "end_pos": 75483606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001527.1", "url": "https://www.ensembl.org/id/ENSGALT00010001527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000833.1", "url": "https://www.ensembl.org/id/ENSGALP00010000833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8854050", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854050", "resource": "Reactome", "description": "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGQ7-1", "protein_name": "F-box/LRR-repeat protein 7", "gene_name": "Fbxl7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPTLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRITDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF", "length": 491 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A1A5X2-1", "protein_name": "F-box/LRR-repeat protein 7", "gene_name": "fbxl7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGANNGKQSGSEGKGSSSISSDLSSSTDQTSTKAPKNAATSEDSDLSMRTVSTPSPALILPPRSSSAVLNGSSTSSSTFGTETIAMVHMPPTSLTHPQRCLRQPRDQQGAPVDILPDHAFLQIFTHLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGDVLHVDRALRVLTRRLCQDTPNVCLTVETVMVSGCRRLTDRGLYTVAQSCPELRRLEVAGCYNVSNEAVFEVVSRCPNLEHLDVSGCSKVTCISLTRDVSVKLSPLHGQQISIRFLDMTDCFALEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRFLVIYCPGVRELSVSDCRFISDFGLREIAKLEGRLRYLSIAHCSRITDVGVRYVAKYCSRLRYLNARGCEGLTDHGIEHLAKSCLKLKSLDIGKCPLVSDAGLEQLALNSFNLKRLSLKSCESITGRGLQVVAANCFDLQLLNVQDCDVSLEALRFVKRHCKRCIIEHTNPAFF", "length": 489 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M6W6-1", "protein_name": "F-box/LRR-repeat protein 7", "gene_name": "Fbxl7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGANNGKQYGSEGKGSSSVSSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPALPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRITDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF", "length": 491 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5BJ29-1", "protein_name": "F-box/LRR-repeat protein 7", "gene_name": "Fbxl7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGANNGKQYGSEGKGSSSVSSDVSSSTDHTPTKAQRNVATSEDSDLSMRTLSTPSPALICPPTLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRITDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF", "length": 491 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C626-1", "protein_name": "F-box protein At1g47056", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGQSTSAAGNSILNRRRSKSFTLKFPIESIESEISQPDYTSSLPDECLALVFQFLNSGNRKRCALVCRRWMIVEGQNRYRLSLHARSDLITSIPSLFSRFDSVTKLSLKCDRRSVSIGDEALVKISLRCRNLKRLKLRACRELTDVGMAAFAENCKDLKIFSCGSCDFGAKGVKAVLDHCSNLEELSIKRLRGFTDIAPEMIGPGVAASSLKSICLKELYNGQCFGPVIVGAKNLKSLKLFRCSGDWDLLLQEMSGKDHGVVEIHLERMQVSDVALSAISYCSSLESLHLVKTPECTNFGLAAIAEKCKRLRKLHIDGWKANLIGDEGLVAVAKFCSQLQELVLIGVNPTTLSLGMLAAKCLNLERLALCGCDTFGDPELSCIAAKCPALRKLCIKNCPISDVGIENLANGCPGLTKVKIKKCKGVLGGCADWLRTVRPMLSVNADTMEQEHEEAASNDVVGGSQENGIEFPQLNSQIMASSIASSSRNRSGYFKSGIGLFSGMSLVPCTSRQRRASR", "length": 518 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UJT9-1", "protein_name": "F-box/LRR-repeat protein 7", "gene_name": "FBXL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF", "length": 491 }, "evidence": [ { "id": "A0A1D5PKG8", "url": "https://omabrowser.org/oma/group/A0A1D5PKG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKG8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKG8" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 157, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 400, "end_pos": 402 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PH70-1", "uniprot_ac": "A0A1D5PH70", "uniprot_id": "A0A1D5PH70_CHICK", "mass": { "chemical_mass": 87704.0, "monoisotopic_mass": 87704.0 }, "refseq": { "ac": "XP_015147257", "name": "intraflagellar transport protein 80 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147257" }, "gene_names": [ { "name": "IFT80", "type": "recommended", "evidence": [ { "id": "A0A1D5PH70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ] }, { "name": "IFT80", "type": "synonym", "evidence": [ { "id": "XP_015147257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147257" } ] } ], "protein_names": [ { "name": "Intraflagellar transport protein 80 homolog", "type": "recommended", "evidence": [ { "id": "A0A1D5PH70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 56", "type": "synonym", "evidence": [ { "id": "A0A1D5PH70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70/entry#names_and_taxonomy" } ] }, { "name": "intraflagellar transport protein 80 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147257" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147257" } ] }, { "annotation": "Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X736", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X736#function" }, { "database": "UniProtKB", "id": "ARBA00057476", "url": "https://www.uniprot.org/uniprotkb/ARBA00057476#function" }, { "database": "UniProtKB", "id": "A0A1D5NZT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZT1#function" }, { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70#function" }, { "database": "UniProtKB", "id": "A0A8V0X9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9R5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFT80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70", "locus": { "chromosome": "9", "start_pos": 21946710, "end_pos": 21903330, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001173", "url": "https://www.ensembl.org/id/ENSGALG00010001173" } ] } } ], "crossref": [ { "id": "A0A1D5PH70", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH70", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009559", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009559", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425014", "url": "https://www.ncbi.nlm.nih.gov/gene/425014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425014", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425014", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDAQGAN", "url": "https://omabrowser.org/oma/group/WDAQGAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZT1", "url": "https://www.orthodb.org/?gene=A0A1D5NZT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PH70", "url": "https://www.orthodb.org/?gene=A0A1D5PH70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X1F3", "url": "https://www.orthodb.org/?gene=A0A8V0X1F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X4E5", "url": "https://www.orthodb.org/?gene=A0A8V0X4E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X4F0", "url": "https://www.orthodb.org/?gene=A0A8V0X4F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X736", "url": "https://www.orthodb.org/?gene=A0A8V0X736", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9R5", "url": "https://www.orthodb.org/?gene=A0A8V0X9R5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24098:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24098:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PH70-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X1F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X736", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X736", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X736-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X736-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9R5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 778, "header": "tr|A0A1D5PH70-1|A0A1D5PH70_CHICK Isoform 1 of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZT1/entry", "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKATATDEDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 784, "header": "tr|A0A1D5NZT1-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=2 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21905574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002705.1", "url": "https://www.ensembl.org/id/ENSGALT00010002705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001255.1", "url": "https://www.ensembl.org/id/ENSGALP00010001255.1" } ] } }, { "isoform_ac": "A0A1D5PH70-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70/entry", "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 778, "header": "tr|A0A1D5PH70-1|A0A1D5PH70_CHICK Isoform 1 of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21905574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002707.1", "url": "https://www.ensembl.org/id/ENSGALT00010002707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001257.1", "url": "https://www.ensembl.org/id/ENSGALP00010001257.1" } ] } }, { "isoform_ac": "A0A8V0X1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1F3/entry", "sequence": { "sequence": "MCLLCCLEYLSEASSFGCQQISHTARWKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 718, "header": "tr|A0A8V0X1F3-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21906561, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002702.1", "url": "https://www.ensembl.org/id/ENSGALT00010002702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001252.1", "url": "https://www.ensembl.org/id/ENSGALP00010001252.1" } ] } }, { "isoform_ac": "A0A8V0X4E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4E5/entry", "sequence": { "sequence": "MSKVSRQNKGRKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 702, "header": "tr|A0A8V0X4E5-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21912945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002701.1", "url": "https://www.ensembl.org/id/ENSGALT00010002701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001251.1", "url": "https://www.ensembl.org/id/ENSGALP00010001251.1" } ] } }, { "isoform_ac": "A0A8V0X4F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4F0/entry", "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 732, "header": "tr|A0A8V0X4F0-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21905574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002706.1", "url": "https://www.ensembl.org/id/ENSGALT00010002706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001256.1", "url": "https://www.ensembl.org/id/ENSGALP00010001256.1" } ] } }, { "isoform_ac": "A0A8V0X736-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X736/entry", "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSIIIRKGEYSCTPPAILSFSLLLVHCLYVLLQKVLLFEVEAAVVLAGCKHVCPSWVTPSTVFFEYCFCTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGLEVDWNKIKAKIEMEIAKERERAAASATVRASVTVQQ", "length": 845, "header": "tr|A0A8V0X736-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21946224, "end_pos": 21905574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002704.1", "url": "https://www.ensembl.org/id/ENSGALT00010002704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001254.1", "url": "https://www.ensembl.org/id/ENSGALP00010001254.1" } ] } }, { "isoform_ac": "A0A8V0X9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9R5/entry", "sequence": { "sequence": "MRLKTSLLKEPKHKELVSCVGWTTADELYSCSDDHQILKWNLLTSETSRVVKLPDDTYPIDLHWLPRSVGGKKQSQAESFVLTSSDGKFHLISKVGRVEKSVEAHSGAVLAGRWNSEGTALATVGEDGQVKIWSKSGMLRSTLAQQGTPVYSVAWGPDSEKVLYTSGKQLIIKPLQPNVKLLQWKAHDGLILKTDWNSVNELILSAGEDCKYKVWDSYGHLLYSSQPHEYPITSVAWSGDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSVDGTQLAGACGNGHVIFAHVVEQRWEWKNFEITLIKRRTMQVHNVINDAVDLLEFRDRVIKASLNYGHLVVSTSLQCYVFSTNNWNTPLIFDLKEGTVTLILQAERHFLLVDGGGLYLYSYEGRLISSPKFPGMRTDILNAQTVSLSNDTLAVKDKADEKVIYIFDAISGKPLGDGKSLTHKTEIVEIALDQKGLTNERKIAFIDKNRDLYITSVKRFGKEQKIVKIGTMVQTLAWNDTSNLLCGIQDTHFTVWYYPNTVYVDKDLLTKTLYEKDASDFSKNPQIVHFVGNQITIRRADGSLIHINISPYPVILHEYVSSSKWEDAVRLCRFVKDQTMWACLAAMAVANKDMATAEIAYASIGEIDKVQYINFIKDLPSKESRMAHILLFSGNTQEAETLLLQTGLIYQAIQVNINLYNWDRALELAVKHKTHVDTVLAYRQKFLEDFGKKETNKRFLQYAEGGKIHLLEFNCAFDSLY", "length": 757, "header": "tr|A0A8V0X9R5-1|A0A1D5PH70_CHICK Computationally mapped isoform of Intraflagellar transport protein 80 homolog OS=Gallus gallus OX=9031 GN=IFT80 PE=1 SV=1 CANONICAL=A0A1D5PH70-1" }, "locus": { "chromosome": "9", "start_pos": 21945984, "end_pos": 21905574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002703.1", "url": "https://www.ensembl.org/id/ENSGALT00010002703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001253.1", "url": "https://www.ensembl.org/id/ENSGALP00010001253.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425014", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0JNF1-1", "protein_name": "Intraflagellar transport protein 80 homolog", "gene_name": "IFT80", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLKISLLKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSQIVKLPDDIYPIDLHWFPKSLGTKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQIKIWSKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRPLYSSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQVAGACGNGHVVFAHVIEQRWEWKNFQVTLTKRRTMQVRNVLNDAVDLLEFRDRVIKASLNYAHLVVSTSLQCYVFSIKNWNTPLIFDLKEGTVSLILQAERHFLLVDGGGIYLYSYEGRFLSAPKFPGMRTDILNAQTVSLSNDTIAIKDKADEKIIFLFEASTGKPLGDGKLLSHKNEILEIALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEEQIIKLGTMVHTLAWSDTCNILCGLQDTRFTVWYYPNTVYVDRDILPKTLYERDASEFSKNPRIVSFVGNQVTVRRADGSLVHISISPYPAILHEYVSSSKWEDAVRLCRFVKEQTIWACLAAMAVANQDMTTAEIAYAAIGEIDKVQYINSIKNLPSKESKMAHMLMFSGNIQEAEIVLLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLETFGKQETNKRYLQYAEGLQIDWEKIKAKIEMEITKERERSSSSQPSKNFSLKH", "length": 777 }, "evidence": [ { "id": "A0A1D5PH70", "url": "https://omabrowser.org/oma/group/A0A1D5PH70/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66HB3-1", "protein_name": "Intraflagellar transport protein 80 homolog", "gene_name": "Ift80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLKISLLKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLGIKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGIPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHVVFAHVVEQRWEWKNFQVTLTKRRTMQVRNVLNDAVDLLEFRDRVIKASLNHAHLVVSTSLQCYVFSTKNWNTPLIFDLKEGTVSLILQAERHFLLVDGGGIYLHSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIKDKADEKIIFLFEASTGKPLGDGKLLSHKNEISEVALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEEQIIKLGTMVHTLAWCDTCNILCGLQDTRFTVWYYPNAVYVDRDILPKTLYERDASEYSKNPHIVSFVGNQVTVRRADGSLVHISISPYPAILHEYVSSSKWEDAVRLCRFVKEQSLWACLAAMAVANRDMVTAEIAYAAVGEIDKVRYINAMKDLPSRESKMAHILMFSGNIQEAETILLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLETFGKQETNKRYLQYAEGLQIDWEKIKAKIEMEITKERDRSSSGQSSKNTGLKP", "length": 777 }, "evidence": [ { "id": "A0A1D5PH70", "url": "https://omabrowser.org/oma/group/A0A1D5PH70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWR1-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "TRIM59", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEITLIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH", "length": 403 }, "evidence": [ { "id": "A0A1D5PH70", "url": "https://omabrowser.org/oma/group/A0A1D5PH70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K057-1", "protein_name": "Intraflagellar transport protein 80 homolog", "gene_name": "Ift80", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLKISLSKEPKHQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLGIKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHVVFAHVVEQRWEWKNFQVTLTKRRTMQVRNVLNDAVDLLEFRDRVIKASLNHAHLVVSTSLQCYVFSTKNWNTPLIFDLKEGTVSLILQAERHFLLVDGGGIYLHSYEGRFISSPKFPGMRTDILNAQTVSLSNDTIAIKDKADEKIIFLFEASTGKPLGDGKLLSHKNEISEIALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEEQIIKLGTMVHTLAWCDTCNILCGIQDTRFTVWYYPNTIYVDRDILPKTLYERDASEYSKNPHIVSFVGNQVTIRRADGSLVHISISPYPAILHEYVSSSKWEEAVRLCRFVKEQSMWACLAAMAVANRDMVTAEIAYAAVGEIDKVRYINAIKDLPSRESKMAHILMFSGNIQEAETVLLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLDTFGKQETNKRYLQYAEGLQIDWEKIKAKIEMEITKERDRSSSGQSSKSVGLKH", "length": 777 }, "evidence": [ { "id": "A0A1D5PH70", "url": "https://omabrowser.org/oma/group/A0A1D5PH70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VII8-1", "protein_name": "Outer segment 5", "gene_name": "Oseg5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLKTRICKKNSIRNSEKVEESSKSTTNCPLSCVDWSSNEEIYFVSDDHQIFKWSDVSRDSVEVAKLPDDFVPTDMHWLLLGGRSSGGGKGSDTLLICSNDGRFVILNKSARVERSISAHAAAISSGRWSPDGAGLLTAGEDGVIKIWSRSGMLRSTVVQNEESIRCARWAPNSNSIVFCQGGHISIKPLAANSKIIRWRAHDGLVLSLSWSTQSNIIASGGEDFRFKIWDAQGANLFTSAAEEYAITSVAFNPEKDYLLVGTFNLLKLCHSNGWSYNTARFSSPRVGSIFNLSWSADGTQATCGTSTGQLIVAYAIEQQLVSGNLKATSKSRKSITLKDIATGTQDILDFPQRVVSFGLGYGHLVVATTNQVHIYNEKYINTPIIIDGRNDTRVIEVGKKYFMILDALSIWVYTYTGRLHLNPRYPGSQAQIPLLTWRSLSLGLDVLAIRDNSDPTVLHLFDLIPGASRQYDPHSLRAKQQLVQIAACRAGSPEDQFVAFIDSNRELFVSESRNLNSERIDEIYKIGTQLTAIMWASETNILVGVHDSCYSIWYCPGEGASDPTIIALTTITLDTTEFGKHITIESFEESVLTFRSAGALLPVNVNMYCEILHRALLEGQWQQALKICRMGQHSSLWATLAAVATRKHQLQISEEAYSAALQIDKVSYLQHLKALTPSSAEQMAENSLMLGRMLEAETILLHGKKIEQAVGLALRMHNWRRALEISQKHKGEQPELVPRVLQERRKYLKALQREEWDPLYLPLVAKEEADNTSE", "length": 775 }, "evidence": [ { "id": "A0A1D5PH70", "url": "https://omabrowser.org/oma/group/A0A1D5PH70/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PH70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" }, { "id": "PF23335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IFT80 second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 588, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PH70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH70" }, { "id": "PF23387", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23387" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IFT80/172/WDR35 TPR", "eco_id": "ECO_0000259", "start_pos": 616, "end_pos": 762, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 426, "end_pos": 428 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 584, "end_pos": 586 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PPP2-1", "uniprot_ac": "A0A1D5PPP2", "uniprot_id": "A0A1D5PPP2_CHICK", "mass": { "chemical_mass": 26180.0, "monoisotopic_mass": 26180.0 }, "refseq": { "ac": "XP_416851", "name": "pseudouridine-5'-phosphatase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416851" }, "gene_names": [ { "name": "PUDP", "type": "recommended", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ] }, { "name": "PUDP", "type": "synonym", "evidence": [ { "id": "XP_416851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416851" } ] } ], "protein_names": [ { "name": "Pseudouridine-5'-phosphatase", "type": "recommended", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.96", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry#names_and_taxonomy" } ] }, { "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 1A", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry#names_and_taxonomy" } ] }, { "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry#names_and_taxonomy" } ] }, { "name": "Pseudouridine-5'-monophosphatase", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry#names_and_taxonomy" } ] }, { "name": "pseudouridine-5'-phosphatase", "type": "synonym", "evidence": [ { "id": "XP_416851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_416851.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416851" } ] }, { "annotation": "Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2#function" }, { "database": "UniProtKB", "id": "ARBA00056605", "url": "https://www.uniprot.org/uniprotkb/ARBA00056605#function" }, { "database": "UniProtKB", "id": "A0A8V0X9S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9S3#function" }, { "database": "UniProtKB", "id": "A0A8V0XCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PUDP", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2", "locus": { "chromosome": "1", "start_pos": 126679647, "end_pos": 126617099, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001738", "url": "https://www.ensembl.org/id/ENSGALG00010001738" } ] } } ], "crossref": [ { "id": "A0A1D5PPP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040388", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418655", "url": "https://www.ncbi.nlm.nih.gov/gene/418655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418655", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHGRRPM", "url": "https://omabrowser.org/oma/group/YHGRRPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPP2", "url": "https://www.orthodb.org/?gene=A0A1D5PPP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9S3", "url": "https://www.orthodb.org/?gene=A0A8V0X9S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCI7", "url": "https://www.orthodb.org/?gene=A0A8V0XCI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18901:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18901:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13419", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13419", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73614", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73614", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10944", "url": "https://www.rhea-db.org/rhea/10944", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASSCSSTAALRPVTHLIFDMDGLLLDTERLYTLVFEEICGRFGKSYTWDVKSLVMGKKALEGAQIIRDVLDLPITKEELLHESKMKQEKIFHTAELMPGVNKLIQHLHKHNIPIAVATSSAEVTFQMKTSRHKDFFNLFHHIVLGDDPEVKGGKPQPDAFLVCAKRFHPPAPPEKCLVFEDSPLGVKGALAAGMQVVMIPDENLSPNLKKEATLLLNSMEDFKPELFGLPAYD", "length": 235, "header": "tr|A0A1D5PPP2-1|A0A1D5PPP2_CHICK Isoform 1 of Pseudouridine-5'-phosphatase OS=Gallus gallus OX=9031 GN=PUDP PE=1 SV=1 CANONICAL=A0A1D5PPP2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2/entry", "sequence": { "sequence": "MSASSCSSTAALRPVTHLIFDMDGLLLDTERLYTLVFEEICGRFGKSYTWDVKSLVMGKKALEGAQIIRDVLDLPITKEELLHESKMKQEKIFHTAELMPGVNKLIQHLHKHNIPIAVATSSAEVTFQMKTSRHKDFFNLFHHIVLGDDPEVKGGKPQPDAFLVCAKRFHPPAPPEKCLVFEDSPLGVKGALAAGMQVVMIPDENLSPNLKKEATLLLNSMEDFKPELFGLPAYD", "length": 235, "header": "tr|A0A1D5PPP2-1|A0A1D5PPP2_CHICK Isoform 1 of Pseudouridine-5'-phosphatase OS=Gallus gallus OX=9031 GN=PUDP PE=1 SV=1 CANONICAL=A0A1D5PPP2-1" }, "locus": { "chromosome": "1", "start_pos": 126676454, "end_pos": 126617267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003971.1", "url": "https://www.ensembl.org/id/ENSGALT00010003971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002270.1", "url": "https://www.ensembl.org/id/ENSGALP00010002270.1" } ] } }, { "isoform_ac": "A0A8V0X9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9S3/entry", "sequence": { "sequence": "MRSTNRILQDTERLYTLVFEEICGRFGKSYTWDVKSLVMGKKALEGAQIIRDVLDLPITKEELLHESKMKQEKIFHTAELMPGVNKLIQHLHKHNIPIAVATSSAEVTFQMKTSRHKDFFNLFHHIVLGDDPEVKGGKPQPDAFLVCAKRFHPPAPPEKCLVFEDSPLGVKGALAAGMQVVMIPDENLSPNLKKEATLLLNSMEDFKPELFGLPAYD", "length": 217, "header": "tr|A0A8V0X9S3-1|A0A1D5PPP2_CHICK Computationally mapped isoform of Pseudouridine-5'-phosphatase OS=Gallus gallus OX=9031 GN=PUDP PE=1 SV=1 CANONICAL=A0A1D5PPP2-1" }, "locus": { "chromosome": "1", "start_pos": 126676454, "end_pos": 126635828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003968.1", "url": "https://www.ensembl.org/id/ENSGALT00010003968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002267.1", "url": "https://www.ensembl.org/id/ENSGALP00010002267.1" } ] } }, { "isoform_ac": "A0A8V0XCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI7/entry", "sequence": { "sequence": "MLPIVTRLEVISLLSLSFHCASCLGDLCYKKTDTERLYTLVFEEICGRFGKSYTWDVKSLVMGKKALEGAQIIRDVLDLPITKEELLHESKMKQEKIFHTAELMPGVNKLIQHLHKHNIPIAVATSSAEVTFQMKTSRHKDFFNLFHHIVLGDDPEVKGGKPQPDAFLVCAKRFHPPAPPEKCLVFEDSPLGVKGALAAGMQVVMIPDENLSPNLKKEATLLLNSMEDFKPELFGLPAYD", "length": 240, "header": "tr|A0A8V0XCI7-1|A0A1D5PPP2_CHICK Computationally mapped isoform of Pseudouridine-5'-phosphatase OS=Gallus gallus OX=9031 GN=PUDP PE=1 SV=1 CANONICAL=A0A1D5PPP2-1" }, "locus": { "chromosome": "1", "start_pos": 126676454, "end_pos": 126624293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003969.1", "url": "https://www.ensembl.org/id/ENSGALT00010003969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002268.1", "url": "https://www.ensembl.org/id/ENSGALP00010002268.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418655", "resource": "KEGG Pathway" }, { "id": "R-GGA-73614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73614", "resource": "Reactome", "description": "Pyrimidine salvage" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ], "pmid": "" }, { "name": "pseudouridine 5'-phosphatase activity", "id": "GO:1990738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990738", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10944", "name": "", "equation": "psi-UMP + H2O = pseudouridine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PPP2-1" ], "evidence": [ { "id": "10944", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10944" } ] }, { "id": "R-GGA-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6788291" ], "output_participant_list": [ "R-ALL-6788290" ], "enzyme_list": [ "A0A1D5PPP2-1" ], "evidence": [ { "id": "R-GGA-6788295", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6788295" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6788290", "participant_name": "PURID [cytosol]", "crossref": [ { "id": "HMDB0000767", "database": "HMDB Metabolite", "url": "" }, { "id": "C02067", "database": "COMPOUND", "url": "" }, { "id": "17802", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095788", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-6788291", "participant_name": "PURIDP [cytosol]", "crossref": [ { "id": "58380", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095566", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PPP2", "gene_name": "PUDP", "activity": [ { "ec_number": "3.1.3.96", "activity": "psi-UMP + H2O = pseudouridine + phosphate.", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ] }, { "ec_number": "3.1.3.96", "activity": "", "evidence": [ { "id": "A0A1D5PPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.96", "ec_name": "psi-UMP + H2O = pseudouridine + phosphate.", "evidence": [ { "id": "3.1.3.96", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.96" }, { "id": "3.1.3.96", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.96" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PWV5-1", "uniprot_ac": "A0A1D5PWV5", "uniprot_id": "A0A1D5PWV5_CHICK", "mass": { "chemical_mass": 8661.0, "monoisotopic_mass": 8661.0 }, "refseq": { "ac": "XP_015158188", "name": "ubiquitin-like protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015158188" }, "gene_names": [ { "name": "UBL5", "type": "recommended", "evidence": [ { "id": "A0A1D5PWV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ] }, { "name": "UBL5", "type": "synonym", "evidence": [ { "id": "XP_015158188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015158188" } ] } ], "protein_names": [ { "name": "Ubiquitin-like protein 5", "type": "recommended", "evidence": [ { "id": "A0A1D5PWV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-like protein 5", "type": "synonym", "evidence": [ { "id": "XP_015158188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015158188" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052561.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015158188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015158188" } ] }, { "annotation": "Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins. Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. Also plays a protective role against ER stress-induced apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5#function" }, { "database": "UniProtKB", "id": "ARBA00059610", "url": "https://www.uniprot.org/uniprotkb/ARBA00059610#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBL5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5", "locus": { "chromosome": "30", "start_pos": 547537, "end_pos": 545472, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002682", "url": "https://www.ensembl.org/id/ENSGALG00010002682" } ] } } ], "crossref": [ { "id": "A0A1D5PWV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PWV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035138", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107057622", "url": "https://www.ncbi.nlm.nih.gov/gene/107057622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107057622", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107057622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMSLEMQ", "url": "https://omabrowser.org/oma/group/GMSLEMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWV5", "url": "https://www.orthodb.org/?gene=A0A1D5PWV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XB37", "url": "https://www.orthodb.org/?gene=A0A8V0XB37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015158188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015158188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTEDSIRDLKKLIAAQTGTRWDKIVLKKWYTIFKDHVTLGDYEIHDGMNLELYYQ", "length": 73, "header": "tr|A0A1D5PWV5-1|A0A1D5PWV5_CHICK Isoform 1 of Ubiquitin-like protein 5 OS=Gallus gallus OX=9031 GN=UBL5 PE=4 SV=1 CANONICAL=A0A1D5PWV5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5/entry", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTEDSIRDLKKLIAAQTGTRWDKIVLKKWYTIFKDHVTLGDYEIHDGMNLELYYQ", "length": 73, "header": "tr|A0A1D5PWV5-1|A0A1D5PWV5_CHICK Isoform 1 of Ubiquitin-like protein 5 OS=Gallus gallus OX=9031 GN=UBL5 PE=4 SV=1 CANONICAL=A0A1D5PWV5-1" }, "locus": { "chromosome": "30", "start_pos": 547243, "end_pos": 546006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006210.1", "url": "https://www.ensembl.org/id/ENSGALT00010006210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003861.1", "url": "https://www.ensembl.org/id/ENSGALP00010003861.1" } ] } }, { "isoform_ac": "A0A8V0XB37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB37/entry", "sequence": { "sequence": "LPVPVWRRSDGGGGAAASLVFSLTGPTSTEDSIRDLKKLIAAQTGTRWDKIVLKKWYTIFKDHVTLGDYEIHDGMNLELYYQ", "length": 82, "header": "tr|A0A8V0XB37-1|A0A1D5PWV5_CHICK Computationally mapped isoform of Ubiquitin-like protein 5 OS=Gallus gallus OX=9031 GN=UBL5 PE=4 SV=1 CANONICAL=A0A1D5PWV5-1" }, "locus": { "chromosome": "30", "start_pos": 547243, "end_pos": 545473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006213.1", "url": "https://www.ensembl.org/id/ENSGALT00010006213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003862.1", "url": "https://www.ensembl.org/id/ENSGALP00010003862.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107057622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107057622", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JK20-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "Ubl5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B4F450-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "UBL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3T0Z3-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "UBL5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6Q546-1", "protein_name": "Ubiquitin-like modifier HUB1", "gene_name": "HUB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MIEVVVNDRLGKKVRVKCLAEDSVGDFKKVLSLQIGTQPNKIVLQKGGSVLKDHISLEDYEVHDQTNLELYYL", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9BZL1-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "UBL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPV8-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "Ubl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FGZ9-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "UBL5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIEVVLNDRLGKKVRVKCNDDDTIGDLKKLVAAQTGTRAEKIRIQKWYNIYKDHITLKDYEIHDGMGLELYYN", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V998-1", "protein_name": "Ubiquitin-like protein 5", "gene_name": "ubl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIEITCNDRLGKKVRVKCNPDDTIGDLKKLIAAQTGTKHEKIVLKKWYTIFKDPIRLSDYEIHDGMNLELYYQ", "length": 73 }, "evidence": [ { "id": "A0A1D5PWV5", "url": "https://omabrowser.org/oma/group/A0A1D5PWV5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PK21-1", "uniprot_ac": "A0A1D5PK21", "uniprot_id": "A0A1D5PK21_CHICK", "mass": { "chemical_mass": 45644.0, "monoisotopic_mass": 45644.0 }, "refseq": { "ac": "XP_418305", "name": "zinc finger protein 704 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418305" }, "gene_names": [ { "name": "ZNF704", "type": "recommended", "evidence": [ { "id": "A0A1D5PK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ] }, { "name": "ZNF704", "type": "synonym", "evidence": [ { "id": "XP_418305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418305" } ] } ], "protein_names": [ { "name": "Zinc finger protein 704", "type": "synonym", "evidence": [ { "id": "A0A1D5PK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 704 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418305" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418305.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF704", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21", "locus": { "chromosome": "2", "start_pos": 120691542, "end_pos": 120783225, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004481", "url": "https://www.ensembl.org/id/ENSGALG00010004481" } ] } } ], "crossref": [ { "id": "A0A1D5PK21", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK21", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030011", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030011", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420194", "url": "https://www.ncbi.nlm.nih.gov/gene/420194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420194", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKVEGSC", "url": "https://omabrowser.org/oma/group/QKVEGSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PK21", "url": "https://www.orthodb.org/?gene=A0A1D5PK21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMR0", "url": "https://www.orthodb.org/?gene=A0A8V0XMR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPJ8", "url": "https://www.orthodb.org/?gene=A0A8V0XPJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13006:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13006:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFE9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK21-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPG3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 412, "header": "tr|A0A1D5PK21-1|A0A1D5PK21_CHICK Isoform 1 of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=2 CANONICAL=A0A1D5PK21-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFE9/entry", "sequence": { "sequence": "MDCRYLKATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 426, "header": "tr|A0A1D5PFE9-1|A0A1D5PFE9_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120757542, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010464.1", "url": "https://www.ensembl.org/id/ENSGALT00010010464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006100.1", "url": "https://www.ensembl.org/id/ENSGALP00010006100.1" } ] } }, { "isoform_ac": "A0A1D5PK21-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21/entry", "sequence": { "sequence": "MTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 412, "header": "tr|A0A1D5PK21-1|A0A1D5PK21_CHICK Isoform 1 of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=2 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120752111, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010457.1", "url": "https://www.ensembl.org/id/ENSGALT00010010457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006095.1", "url": "https://www.ensembl.org/id/ENSGALP00010006095.1" } ] } }, { "isoform_ac": "A0A1L1RPG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPG3/entry", "sequence": { "sequence": "MTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 377, "header": "tr|A0A1L1RPG3-1|A0A1L1RPG3_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=2 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120752111, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010459.1", "url": "https://www.ensembl.org/id/ENSGALT00010010459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006096.1", "url": "https://www.ensembl.org/id/ENSGALP00010006096.1" } ] } }, { "isoform_ac": "A0A8V0XD90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD90/entry", "sequence": { "sequence": "MERKSFSCIFSSALQVVETKATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 439, "header": "tr|A0A8V0XD90-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120762100, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010465.1", "url": "https://www.ensembl.org/id/ENSGALT00010010465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006101.1", "url": "https://www.ensembl.org/id/ENSGALP00010006101.1" } ] } }, { "isoform_ac": "A0A8V0XJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ2/entry", "sequence": { "sequence": "MTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRRKEKAEFSRRTNCSWKAFKPGTDRQSGTE", "length": 438, "header": "tr|A0A8V0XJZ2-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120752111, "end_pos": 120692546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010462.1", "url": "https://www.ensembl.org/id/ENSGALT00010010462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006098.1", "url": "https://www.ensembl.org/id/ENSGALP00010006098.1" } ] } }, { "isoform_ac": "A0A8V0XJZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJZ7/entry", "sequence": { "sequence": "MQARRLAKRSSMGSRRLSAGPAAAQADGARPPKPESAWRPPRREGSAAAVEEEDEDEDVVVEVEEEEEEEEGGLGSPPPALSAHGKGPLRASLKATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 513, "header": "tr|A0A8V0XJZ7-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120769981, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010469.1", "url": "https://www.ensembl.org/id/ENSGALT00010010469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006103.1", "url": "https://www.ensembl.org/id/ENSGALP00010006103.1" } ] } }, { "isoform_ac": "A0A8V0XMR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR0/entry", "sequence": { "sequence": "MCATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 421, "header": "tr|A0A8V0XMR0-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120753983, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010455.1", "url": "https://www.ensembl.org/id/ENSGALT00010010455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006094.1", "url": "https://www.ensembl.org/id/ENSGALP00010006094.1" } ] } }, { "isoform_ac": "A0A8V0XMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMR5/entry", "sequence": { "sequence": "MATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 420, "header": "tr|A0A8V0XMR5-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120760676, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010463.1", "url": "https://www.ensembl.org/id/ENSGALT00010010463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006099.1", "url": "https://www.ensembl.org/id/ENSGALP00010006099.1" } ] } }, { "isoform_ac": "A0A8V0XMS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMS0/entry", "sequence": { "sequence": "MDTTVSKATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 426, "header": "tr|A0A8V0XMS0-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120783220, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010470.1", "url": "https://www.ensembl.org/id/ENSGALT00010010470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006104.1", "url": "https://www.ensembl.org/id/ENSGALP00010006104.1" } ] } }, { "isoform_ac": "A0A8V0XPJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ8/entry", "sequence": { "sequence": "MRKKSLPTSEEATSIKREMTFPAFQQEDVKTDISQKLPDQQFLLFTTKEEDLKTAETKKTSRIHEYEKENTRSVCLLEQKRKVVSSNIDVPPARKSPEELDMDKVTAAMVLTSLSTSPLVRSPPIRPNESLNGSWKEGGFVPSSTSSSGYWSWNAPSDQSNPSTPSPPLSADSFKAFRTPSQPDDGIDEAETSNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGESDYSDGEEDFYYTEIRLNTDSVADGLSSLSPVSPSLASPPSFSTQDAIRPETSCAKTETKLMTPLSRSAPTNLYLVHTDHAYQATPPVNIPGSTKFTPNGSSFSISWQSPPVTFTGIPVSPTHNRPAGSGEQKQSHTVLSSPPRVAFGLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 430, "header": "tr|A0A8V0XPJ8-1|A0A1D5PK21_CHICK Computationally mapped isoform of Zinc finger protein 704 OS=Gallus gallus OX=9031 GN=ZNF704 PE=4 SV=1 CANONICAL=A0A1D5PK21-1" }, "locus": { "chromosome": "2", "start_pos": 120767041, "end_pos": 120693317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010467.1", "url": "https://www.ensembl.org/id/ENSGALT00010010467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006102.1", "url": "https://www.ensembl.org/id/ENSGALP00010006102.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 146, "start_aa": "Thr", "end_pos": 146, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 311, "start_aa": "Thr", "end_pos": 311, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr311", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420194", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420194", "resource": "KEGG Pathway" }, { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M3C0-1", "protein_name": "Zinc finger protein 704", "gene_name": "Zfp704", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQARRLAKRPSLGSRRGGAAPAPAPEAAALGLPPPGPSPAAAPGSWRPPLPPPRGTGPPRAAAASSPVLLLLGEEDEDEEGAGRRRRTRGRVAEKPRGGAEEEEDDEEEDEEVVVEVVDGDEDDEDSEERFVPLGPGRALPKGPARGAVKVGSFKREMTFTYQSEDFRRDSSKKLSHHLFPLAMEEDVRTADTKKASRILDQDKETRSVCLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNEGLSGSWKEGAPSSSSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPVPLDDGIDEAEASNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLNTAAGIQKHIRAVHLGRVGESDCSDGEEDFYYTEIKLNTDAVAEGLNSVAPVSPSQSLASPPTFPIPDSSRAETPCAKTDTKLVTPLSRSAPTTLYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGVPKAQRRRQKVPQGLRDGKQGHVVHRLPLEEGLPAVHRLSRGAGSPQPFLPLPLKGATQGPGKALLEFQEYNSLVELKQKLSTALL", "length": 581 }, "evidence": [ { "id": "A0A1D5PK21", "url": "https://omabrowser.org/oma/group/A0A1D5PK21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LY51-1", "protein_name": "Zinc finger protein 704", "gene_name": "znf704", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHTRRLVKRSVIGSRVYAPGLTGDAAPLTGVIQAVKQDNRDASTGHRRNVYTVLMQDGSVKEYSEEEIAQMTAKAPLKSSLKSTCNGGQRDGLTQGQNGGVQRGEALSLSPESTEEPRVLEHKRTGRALETEKDHTRSVSLLEQKRKVVSSSIDVPQARKSEEEVDMDKVTAAMVLTSLSTSPLVRSPPVKVSEGLNGSWKDGGFTPSSYSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRMPSLSGPPDDNIDEHDGNSLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQRHIRTVHLGRNCDSECSDGEEDFYYTEIKLNTDSVADGLSSLSPVSPSVLSPPPALDQRQPDGTNGTKSESSSSTPLSRSAPSALYLVHTDHAYQATTPVTIPSTSSTGFTPSSSSFSISWQSPPVTFTGTSASPTHSRTQGFGEQHSQTIAVLSSPPRAAGSLSRKSRGEGKKCRKVYGMENRDMWCTACRWKKACQRFVD", "length": 501 }, "evidence": [ { "id": "A0A1D5PK21", "url": "https://omabrowser.org/oma/group/A0A1D5PK21/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZNC4-1", "protein_name": "Zinc finger protein 704", "gene_name": "ZNF704", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTFTFQSEDLKRDCGKKMSHQHVFSLAMEEDVKTADTKKASRILDHEKENTRSICLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNESLSGSWKEGGCVPSSTSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPAQPDDGIDEAEASNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGDSDYSDGEEDFYYTEIKLNTDSVADGLSSLAPVSPSQSLASPPTFPIPDSSRTETPCAKTETKLMTPLSRSAPTTLYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGIPVSPTHHPVGTGEQRQHAHTVLSSPPRGTVSLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFLD", "length": 412 }, "evidence": [ { "id": "A0A1D5PK21", "url": "https://omabrowser.org/oma/group/A0A1D5PK21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERQ3-1", "protein_name": "Zinc finger protein 704", "gene_name": "Znf704", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQARRLAKRPSLGSRRGGAAPAPAPEAAALGLPPPGPSPAAAPGSWRPPLPPPRGTGPSRAAAASSPVLLLLGEEDEDEEGAGRRRRTRGRVTEKPRGVAEEEDDDEEEDEEVVVEVVDGDEDDEDAEERFVPLGPGRALPKGPARGAVKVGSFKREMTFTFQSEDFRRDSSKKPSHHLFPLAMEEDVRTADTKKTSRVLDQEKETRSVCLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNEGLSGSWKEGAPSSSSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPAPPDDGIDEADASNLLFDEPIPRKRKNSMKVMFKCLWKSCGKVLNTAAGIQKHIRAVHLGRVGESDCSDGEEDFYYTEIKLNTDATAEGLNTVAPVSPSQSLASAPAFPIPDSSRTETPCAKTDTKLVTPLSRSAPTTLYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGVPVSPPHHPTAGSGEQRQHAHTALSSPPRGTVTLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFID", "length": 566 }, "evidence": [ { "id": "A0A1D5PK21", "url": "https://omabrowser.org/oma/group/A0A1D5PK21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 146, 311 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 325, "end_pos": 327 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PT30-1", "uniprot_ac": "A0A1D5PT30", "uniprot_id": "A0A1D5PT30_CHICK", "mass": { "chemical_mass": 23875.0, "monoisotopic_mass": 23875.0 }, "refseq": { "ac": "NP_001025224", "name": "large ribosomal subunit protein mL48", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025224" }, "gene_names": [ { "name": "MRPL48", "type": "recommended", "evidence": [ { "id": "A0A1D5PT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ] }, { "name": "MRPL48", "type": "synonym", "evidence": [ { "id": "NP_001025224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025224" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL48", "type": "recommended", "evidence": [ { "id": "A0A1D5PT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L48, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A1D5PT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein mL48", "type": "synonym", "evidence": [ { "id": "NP_001025224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025224" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934907.1, BU124031.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX950666.1, BX934907.1 and BU258502.1. On Aug 6, 2005 this sequence version replaced XP_417253.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL48", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30", "locus": { "chromosome": "1", "start_pos": 194867300, "end_pos": 194878592, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002577", "url": "https://www.ensembl.org/id/ENSGALG00010002577" } ] } } ], "crossref": [ { "id": "A0A1D5PT30", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PT30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017319", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017319", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419062", "url": "https://www.ncbi.nlm.nih.gov/gene/419062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419062", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKQHTEA", "url": "https://omabrowser.org/oma/group/MKQHTEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PT30", "url": "https://www.orthodb.org/?gene=A0A1D5PT30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XDI5", "url": "https://www.orthodb.org/?gene=A0A8V0XDI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XDJ0", "url": "https://www.orthodb.org/?gene=A0A8V0XDJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13473:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13473:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PT30-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVVLCLKKGTLLKQVFALSRAATPRESCLCAAGDALVDFHRHYRSRPTHGIGKYKHLLPKEVPKRKRGRVQMKEINVGTEHEYGDINIQMTSYDMCLVEHFAQYVHKLCNQLSIRVNESYAMPTKTNEVLFMEERGSKMQVDAVLTTHQRVVQISRLSSTFAPILLEIIQSNQPEGVHLLMKEHTETDFKSRLKSRPELEELLAQVS", "length": 209, "header": "tr|A0A1D5PT30-1|A0A1D5PT30_CHICK Isoform 1 of Large ribosomal subunit protein mL48 OS=Gallus gallus OX=9031 GN=MRPL48 PE=1 SV=1 CANONICAL=A0A1D5PT30-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PT30-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30/entry", "sequence": { "sequence": "MSAVVLCLKKGTLLKQVFALSRAATPRESCLCAAGDALVDFHRHYRSRPTHGIGKYKHLLPKEVPKRKRGRVQMKEINVGTEHEYGDINIQMTSYDMCLVEHFAQYVHKLCNQLSIRVNESYAMPTKTNEVLFMEERGSKMQVDAVLTTHQRVVQISRLSSTFAPILLEIIQSNQPEGVHLLMKEHTETDFKSRLKSRPELEELLAQVS", "length": 209, "header": "tr|A0A1D5PT30-1|A0A1D5PT30_CHICK Isoform 1 of Large ribosomal subunit protein mL48 OS=Gallus gallus OX=9031 GN=MRPL48 PE=1 SV=1 CANONICAL=A0A1D5PT30-1" }, "locus": { "chromosome": "1", "start_pos": 194877257, "end_pos": 194869062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005909.1", "url": "https://www.ensembl.org/id/ENSGALT00010005909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003676.1", "url": "https://www.ensembl.org/id/ENSGALP00010003676.1" } ] } }, { "isoform_ac": "A0A8V0XDI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDI5/entry", "sequence": { "sequence": "RKTNQLARREPENQSVRGGRAVPRRSVPAVGARTSEGLRYLGLQGWGIHNVLGQPVPVRHHPLGEKPRTVSVVLCLKKGTLLKQVFALSRAATPRESCLCAAGDALVDFHRHYRSRPTHGIGKYKHLLPKEVPKRKRGRVQMKEINVGTEHEYGDINIQMTSYDMCLVEHFAQYVHKLCNQLSIRVNESYAMPTKTNEVLFMEERGSKMQVDAVLTTHQRVVQISRLSSTFAPILLEIIQSNQPEGVHLLMKEHTETDFKSRLKSRPELEELLAQVS", "length": 277, "header": "tr|A0A8V0XDI5-1|A0A1D5PT30_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL48 OS=Gallus gallus OX=9031 GN=MRPL48 PE=1 SV=1 CANONICAL=A0A1D5PT30-1" }, "locus": { "chromosome": "1", "start_pos": 194878393, "end_pos": 194869062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005908.1", "url": "https://www.ensembl.org/id/ENSGALT00010005908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003674.1", "url": "https://www.ensembl.org/id/ENSGALP00010003674.1" } ] } }, { "isoform_ac": "A0A8V0XDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDJ0/entry", "sequence": { "sequence": "MGQHPQGPGHARKVLCLKKGTLLKQVFALSRAATPRESCLCAAGDALVDFHRHYRSRPTHGIGKYKHLLPKEVPKRKRGRVQMKEINVGTEHEYGDINIQMTSYDMCLVEHFAQYVHKLCNQLSIRVNESYAMPTKTNEVLFMEERGSKMQVDAVLTTHQRVVQISRLSSTFAPILLEIIQSNQPEGVHLLMKEHTETDFKSRLKSRPELEELLAQVS", "length": 218, "header": "tr|A0A8V0XDJ0-1|A0A1D5PT30_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL48 OS=Gallus gallus OX=9031 GN=MRPL48 PE=1 SV=1 CANONICAL=A0A1D5PT30-1" }, "locus": { "chromosome": "1", "start_pos": 194878058, "end_pos": 194869062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005912.1", "url": "https://www.ensembl.org/id/ENSGALT00010005912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003679.1", "url": "https://www.ensembl.org/id/ENSGALP00010003679.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419062", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LPD6-1", "protein_name": "Large ribosomal subunit protein mL48", "gene_name": "Mrpl48", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHQLEFPQRIPEVSARGHDGAGGAAAAASAQRPLPDRCSSNPLTKRAERKGQPRSPLGPCRAEQRGEAEGRVTPPTGSRRRRLPAESPSTQPGPRPRRDAGRCRRQPAVRSGFASLAPFLPSERGAETELSGLLPCRGERGRSGFDWRLEKTGGGGTEFRVLGLWTNTVSKQGFSLQRFRILGENPIYSAGGIVRTSRHYKTKPTHGIGRYRHLVKVLEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMTLAESYARYVHRLCNQLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEILQINLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN", "length": 364 }, "evidence": [ { "id": "A0A1D5PT30", "url": "https://omabrowser.org/oma/group/A0A1D5PT30/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I9W5-1", "protein_name": "Large ribosomal subunit protein mL48", "gene_name": "Mrpl48", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGTLGKVLGLWKDTVSKQAFSLLRFRILGENPICSAGGILLRPRQHYKTKPTHGIGRYKHLVKVLEPQKKKAKVDVRAINVGTDYEYGVLNIHLTAYDMTLAESYAQYVHRLCNQLSIKVEESYAMPTKTIEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEILQRNLPEGVRLSVREHSEEDFKGRFKARPELEELLAKLN", "length": 212 }, "evidence": [ { "id": "A0A1D5PT30", "url": "https://omabrowser.org/oma/group/A0A1D5PT30/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2YDI5-1", "protein_name": "Large ribosomal subunit protein mL48", "gene_name": "MRPL48", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGALGKVLCLKNDTIFKQAFSLLRFRTSGENPVYSAGGILLTTSRHYRSKPTHGIGRYKHLVKPEEPKKKKGKVEIRAINVGTDYEYGTLNIHLIAYDMALTESYAQYVHNLCNHLSIKVEESYAMPTKTMEVLQLQDQGNKMLLDSVLTTHERVVQISGLNATFAEIFLEIIQSNLPEGVKLSVREHTEEDFKGRFKARPELEELLAKLN", "length": 212 }, "evidence": [ { "id": "A0A1D5PT30", "url": "https://omabrowser.org/oma/group/A0A1D5PT30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8JZS9-1", "protein_name": "Large ribosomal subunit protein mL48", "gene_name": "Mrpl48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGTLGKVLGVWTNTVSKQGFSLLRFRSLGENPIFSAGGILWTSRHYKTKPTHGIGRYRHLVKVQEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMSLAESYAQYVHRLCNRLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEVLQSNLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN", "length": 211 }, "evidence": [ { "id": "A0A1D5PT30", "url": "https://omabrowser.org/oma/group/A0A1D5PT30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GC5-1", "protein_name": "Large ribosomal subunit protein mL48", "gene_name": "MRPL48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEPKKKKGKVEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTIEVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHTEEDFKGRFKARPELEELLAKLK", "length": 212 }, "evidence": [ { "id": "A0A1D5PT30", "url": "https://omabrowser.org/oma/group/A0A1D5PT30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ], "pmid": "" }, { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PT30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PT30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT30" }, { "id": "SM01403", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01403" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS10", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 184, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJH0-1", "uniprot_ac": "A0A1D5PJH0", "uniprot_id": "A0A1D5PJH0_CHICK", "mass": { "chemical_mass": 15721.0, "monoisotopic_mass": 15721.0 }, "refseq": { "ac": "XP_040528706", "name": "ergosterol biosynthetic protein 28 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528706" }, "gene_names": [ { "name": "ERG28", "type": "recommended", "evidence": [ { "id": "A0A1D5PJH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ] }, { "name": "ERG28", "type": "synonym", "evidence": [ { "id": "XP_040528706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528706" } ] } ], "protein_names": [ { "name": "Ergosterol biosynthesis 28 homolog", "type": "synonym", "evidence": [ { "id": "A0A1D5PJH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0/entry#names_and_taxonomy" } ] }, { "name": "ergosterol biosynthetic protein 28 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040528706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528706" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040528706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528706" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERG28", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0", "locus": { "chromosome": "5", "start_pos": 37835977, "end_pos": 37837672, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005077", "url": "https://www.ensembl.org/id/ENSGALG00010005077" } ] } } ], "crossref": [ { "id": "A0A1D5PJH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034354", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034354", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423366", "url": "https://www.ncbi.nlm.nih.gov/gene/423366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423366", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIAIWTY", "url": "https://omabrowser.org/oma/group/NIAIWTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJH0", "url": "https://www.orthodb.org/?gene=A0A1D5PJH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLK2", "url": "https://www.orthodb.org/?gene=A0A8V0XLK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15451:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15451:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040528706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFLNVLRSWLVMVSVIAAGNTLQSFRDHSFLSEKLYTGSPGLVNGLQARTFGIWTLLSSVIRCLCAIDIRNQTLYYLTLFTFFMALVHFLSEVFIYHTAALTIGVMAPLMVASFSILGMLIGLQYLEVEALSENKKKN", "length": 140, "header": "tr|A0A1D5PJH0-1|A0A1D5PJH0_CHICK Isoform 1 of Ergosterol biosynthesis 28 homolog OS=Gallus gallus OX=9031 GN=ERG28 PE=1 SV=1 CANONICAL=A0A1D5PJH0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0/entry", "sequence": { "sequence": "MSRFLNVLRSWLVMVSVIAAGNTLQSFRDHSFLSEKLYTGSPGLVNGLQARTFGIWTLLSSVIRCLCAIDIRNQTLYYLTLFTFFMALVHFLSEVFIYHTAALTIGVMAPLMVASFSILGMLIGLQYLEVEALSENKKKN", "length": 140, "header": "tr|A0A1D5PJH0-1|A0A1D5PJH0_CHICK Isoform 1 of Ergosterol biosynthesis 28 homolog OS=Gallus gallus OX=9031 GN=ERG28 PE=1 SV=1 CANONICAL=A0A1D5PJH0-1" }, "locus": { "chromosome": "5", "start_pos": 37837578, "end_pos": 37836430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011956.1", "url": "https://www.ensembl.org/id/ENSGALT00010011956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006686.1", "url": "https://www.ensembl.org/id/ENSGALP00010006686.1" } ] } }, { "isoform_ac": "A0A8V0XLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK2/entry", "sequence": { "sequence": "MSRFLNVLRSWLVMVSVIAAGNTLQSFRDHSFLSEKLYTGSPGLVNGLQARTFGIWTLLSSVIRCLCAIDIRNQTLYYLTLFTFFMALVHFLSEVFIYHTAALTIGVMAPLMVASKQSPAPCLPAPTSGGALGSLRTTCGARRGCSERLICVQPFFIQLMLYLHRRFLYPGDADRATVPRGRSTVRK", "length": 187, "header": "tr|A0A8V0XLK2-1|A0A1D5PJH0_CHICK Computationally mapped isoform of Ergosterol biosynthesis 28 homolog OS=Gallus gallus OX=9031 GN=ERG28 PE=1 SV=1 CANONICAL=A0A1D5PJH0-1" }, "locus": { "chromosome": "5", "start_pos": 37837578, "end_pos": 37836443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011960.1", "url": "https://www.ensembl.org/id/ENSGALT00010011960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006689.1", "url": "https://www.ensembl.org/id/ENSGALP00010006689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423366", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LSP8-1", "protein_name": "Ergosterol biosynthetic protein 28 homolog", "gene_name": "Erg28", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFIFGTAAPTVGVLAPLMVASLSILGMLIGLRYLEAEPVSRQKKRN", "length": 140 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZBN4-1", "protein_name": "Ergosterol biosynthesis 28 homolog", "gene_name": "Erg28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFVFGTAAPTVGVLAPLMVASFSILGMLVGLRYLEAEPVSRQKKRN", "length": 140 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40030-1", "protein_name": "Ergosterol biosynthetic protein 28", "gene_name": "ERG28", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFSLQDVITTTKTTLAAMPKGYLPKWLLFISIVSVFNSIQTYVSGLELTRKVYERKPTETTHLSARTFGTWTFISCVIRFYGAMYLNEPHIFELVFMSYMVALFHFGSELLIFRTCKLGKGFMGPLVVSTTSLVWMYKQREYYTGVAW", "length": 148 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54G55-1", "protein_name": "Ergosterol biosynthetic protein 28 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQKISIWLLVVASLRLLGASQAFFNQSRIKSNVYSGDQKSINPLFCRLFGSWTMMSFTLCVATAFNPFNKALYACTFVSFLIAGGHFVTECFIYKTSRIKDAISPFIVAGTSMFWMGYELLNW", "length": 123 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9ERY9-1", "protein_name": "Ergosterol biosynthetic protein 28 homolog", "gene_name": "Erg28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFVFGTAAPTVGVLAPLMVASFSILGMLVGLRYLEAEPVSRQKKRN", "length": 140 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKR5-1", "protein_name": "Ergosterol biosynthetic protein 28 homolog", "gene_name": "ERG28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFVYGTAAPTIGVLAPLMVASFSILGMLVGLRYLEVEPVSRQKKRN", "length": 140 }, "evidence": [ { "id": "A0A1D5PJH0", "url": "https://omabrowser.org/oma/group/A0A1D5PJH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJH0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P7R3-1", "uniprot_ac": "A0A1D5P7R3", "uniprot_id": "A0A1D5P7R3_CHICK", "mass": { "chemical_mass": 46488.0, "monoisotopic_mass": 46488.0 }, "refseq": { "ac": "XP_015137109", "name": "UPF0415 protein C7orf25 homolog isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137109" }, "gene_names": [ { "name": "C7orf25", "type": "recommended", "evidence": [ { "id": "A0A1D5P7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3" } ] }, { "name": "C7orf25", "type": "synonym", "evidence": [ { "id": "XP_015137109", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137109" } ] } ], "protein_names": [ { "name": "Chromosome 7 open reading frame 25", "type": "synonym", "evidence": [ { "id": "A0A1D5P7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3/entry#names_and_taxonomy" } ] }, { "name": "UPF0415 protein C7orf25 homolog isoform X5", "type": "synonym", "evidence": [ { "id": "XP_015137109", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137109" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137109" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7R3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C7orf25", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3", "locus": { "chromosome": "2", "start_pos": 51145245, "end_pos": 51152365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007902", "url": "https://www.ensembl.org/id/ENSGALG00010007902" } ] } } ], "crossref": [ { "id": "ENSGALG00000040161", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420771", "url": "https://www.ncbi.nlm.nih.gov/gene/420771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420771", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420771", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HFCMFQR", "url": "https://omabrowser.org/oma/group/HFCMFQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7R3", "url": "https://www.orthodb.org/?gene=A0A1D5P7R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AQB2", "url": "https://www.orthodb.org/?gene=A0A3Q3AQB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AZZ9", "url": "https://www.orthodb.org/?gene=A0A3Q3AZZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13379:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13379:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137109", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7R3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AQB2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AQB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AZZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AZZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AZZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AZZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVQSLLCERIVVAKELIKRAEALSKFQKRKIEGGAKLCGKLKAELNFLHKVESGKVVIKESHLQSTNLTHLQAIIQSAENLEDVVSVLQVFSYEDRFGNRQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASCQQPVEYSNPHIIFAFYNSVSSPMAERLKEMGISVRGDVVAVSSLVEPSVENQHLSASESDEEGLELQVTRVDRENLVTSIAFPSQIKVNVCNRVNLDITTLITYVSALNYGGCYFLFKEKVLTEQAAQERRERVLPQLEEFMEGKELFACESAVRDFQSILETLGGPGEKKRAALLVKRISVVPDQPSDRALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAAANQGVKFSVFVHQPRALTESKESVATPLPKSCLHDNGL", "length": 421, "header": "tr|A0A1D5P7R3-1|A0A1D5P7R3_CHICK Isoform 1 of Chromosome 7 open reading frame 25 OS=Gallus gallus OX=9031 GN=C7orf25 PE=3 SV=1 CANONICAL=A0A1D5P7R3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3/entry", "sequence": { "sequence": "MSVQSLLCERIVVAKELIKRAEALSKFQKRKIEGGAKLCGKLKAELNFLHKVESGKVVIKESHLQSTNLTHLQAIIQSAENLEDVVSVLQVFSYEDRFGNRQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASCQQPVEYSNPHIIFAFYNSVSSPMAERLKEMGISVRGDVVAVSSLVEPSVENQHLSASESDEEGLELQVTRVDRENLVTSIAFPSQIKVNVCNRVNLDITTLITYVSALNYGGCYFLFKEKVLTEQAAQERRERVLPQLEEFMEGKELFACESAVRDFQSILETLGGPGEKKRAALLVKRISVVPDQPSDRALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAAANQGVKFSVFVHQPRALTESKESVATPLPKSCLHDNGL", "length": 421, "header": "tr|A0A1D5P7R3-1|A0A1D5P7R3_CHICK Isoform 1 of Chromosome 7 open reading frame 25 OS=Gallus gallus OX=9031 GN=C7orf25 PE=3 SV=1 CANONICAL=A0A1D5P7R3-1" }, "locus": { "chromosome": "2", "start_pos": 51147211, "end_pos": 51145949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018811.1", "url": "https://www.ensembl.org/id/ENSGALT00010018811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010361.1", "url": "https://www.ensembl.org/id/ENSGALP00010010361.1" } ] } }, { "isoform_ac": "A0A3Q3AQB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AQB2/entry", "sequence": { "sequence": "MMEDLRQSLIRKERFWNDVSNMSVQSLLCERIVVAKELIKRAEALSKFQKRKIEGGAKLCGKLKAELNFLHKVESGKVVIKESHLQSTNLTHLQAIIQSAENLEDVVSVLQVFSYEDRFGNRQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASCQQPVEYSNPHIIFAFYNSVSSPMAERLKEMGISVRGDVVAVSSLVEPSVENQHLSASESDEEGLELQVTRVDRENLVTSIAFPSQIKVNVCNRVNLDITTLITYVSALNYGGCYFLFKEKVLTEQAAQERRERVLPQLEEFMEGKELFACESAVRDFQSILETLGGPGEKKRAALLVKRISVVPDQPSDRALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAAANQGVKFSVFVHQPRALTESKESVATPLPKSCLHDNGL", "length": 442, "header": "tr|A0A3Q3AQB2-1|A0A1D5P7R3_CHICK Computationally mapped isoform of Chromosome 7 open reading frame 25 OS=Gallus gallus OX=9031 GN=C7orf25 PE=3 SV=1 CANONICAL=A0A1D5P7R3-1" }, "locus": { "chromosome": "2", "start_pos": 51150197, "end_pos": 51147673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018806.1", "url": "https://www.ensembl.org/id/ENSGALT00010018806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010356.1", "url": "https://www.ensembl.org/id/ENSGALP00010010356.1" } ] } }, { "isoform_ac": "A0A3Q3AZZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AZZ9/entry", "sequence": { "sequence": "MRVAWRIAPNWWWAGTVRELRLAAVLRGYFSLFPNDVSNMSVQSLLCERIVVAKELIKRAEALSKFQKRKIEGGAKLCGKLKAELNFLHKVESGKVVIKESHLQSTNLTHLQAIIQSAENLEDVVSVLQVFSYEDRFGNRQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASCQQPVEYSNPHIIFAFYNSVSSPMAERLKEMGISVRGDVVAVSSLVEPSVENQHLSASESDEEGLELQVTRVDRENLVTSIAFPSQIKVNVCNRVNLDITTLITYVSALNYGGCYFLFKEKVLTEQAAQERRERVLPQLEEFMEGKELFACESAVRDFQSILETLGGPGEKKRAALLVKRISVVPDQPSDRALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAAANQGVKFSVFVHQPRALTESKESVATPLPKSCLHDNGL", "length": 460, "header": "tr|A0A3Q3AZZ9-1|A0A1D5P7R3_CHICK Computationally mapped isoform of Chromosome 7 open reading frame 25 OS=Gallus gallus OX=9031 GN=C7orf25 PE=3 SV=1 CANONICAL=A0A1D5P7R3-1" }, "locus": { "chromosome": "2", "start_pos": 51151253, "end_pos": 51147673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018807.1", "url": "https://www.ensembl.org/id/ENSGALT00010018807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010357.1", "url": "https://www.ensembl.org/id/ENSGALP00010010357.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420771", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420771", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SSE3-1", "protein_name": "Chromosome 18 C7orf25 homolog", "gene_name": "C7orf25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDALGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLREMGISVRGDIVAVNSLLDHPEELQLSERESDDEGPELLQVTRVDRENILARVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFVFKEKVLTEQAEQERKEQVLPELEAFMKDKELFACESAVKDFQSILDTLGGPGERERAALLIKRINVVPDQPSERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDCTTDSKH", "length": 421 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HSF2-1", "protein_name": "UPF0415 protein C7orf25 homolog", "gene_name": "C3H7orf25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSAHSMLSERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKIEAGKVAIKESHLQSTNLTHLKAIVESAENLEEVVSVLRVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIVFAFYNSVSSPMAEKLKDMGISVRGDIVAVNSLLNHPEELELSESELDDEGQELLQVTRVDRENVLAHVAFPTEIKVDVCKRVNLDITTLITYVSAMSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATLLIKRISVVPDQPSERALRLVASSKINSRSLTIFGTGDNLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALAVPLPKDFTNESAH", "length": 421 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5M888-1", "protein_name": "UPF0415 protein C7orf25 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAYSMLSERIAMAKELIKRAESLSRSKKGGIEGGAKLCSKLKSELKFLQKIESGKVAIKESHLQSTNLTHLKAIVESAENLEEVVSVLRVFGYTDSLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASRQQPVQYSNPHIVFAFYNSVSSPMADKLKDMGISVRGDIVAVNSLLNHPEEYLLSESESDDEGQELLQVTRVDLDNVLARVAFPTEIKVDVCRRVNLDITTLITYVSAMSYGGCHFIFKEKVLTEQAEQERKERVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAVLIKRINVVPDQPSERALKLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALAVPLPKARTNDSAH", "length": 421 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q803H0-1", "protein_name": "UPF0415 protein C7orf25 homolog", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATYNTLQDRIRVAKELLERVDKICSRQGREVEGRAKLCGKLRAELKFLQKVEAGKVVIKESHLQSTNLTHLKAIVESAESLEKVVSVLHVFAYESPDGQKQTLVVDVVANGGHTWVKSIGRKAEALHNIWQGRGQYGDKSVIRQAEDFLEASQQQPVQYSNPHIIFAFYNGVSSPMADKLKEMGISVRGDIVAVNTIEGGEEEDEEDQEGDHEDLVEEEEDGEDDNDDDSDDTDLMHTRVDRDTIVASLAFPTEVKVDVCNRVNLDITTLITYVSSLSHGNCHFTFKEVVLTEQAAQERQEKVLPRLEEFMKGKELFACQSAVEDFRVILDTLGGPGEKSRAEELLARLKVVPDQPSERTQRLVMSSKVNRRSLMIFGTGDTLRAITMTANSGFVRAAANQGVRFSVFIHQPRALTEGKEWRATPI", "length": 427 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91WD4-1", "protein_name": "UPF0415 protein C7orf25 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAYSMLSDRIVMAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKIEAGKVAIKESHLQSTNLTHLKAIVESAENLEEVVSVLRVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASRQQPVQYSNPHIVFAFYNSVSSPMADKLKDMGISVRGDIVAVNSLLNHPEEFQLSESESDDEGQELLQVTRVDRDNVLARVAFPTEIKVDVCKKVNLDITTLITYVSAMSYGGCHFVFKEKVLTEQAEQERKERVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERADVLIKRISVVPDQPSERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEAFAVPLPKDLTDDSAH", "length": 421 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BPX7-1", "protein_name": "UPF0415 protein C7orf25", "gene_name": "C7orf25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNALLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATVLIKRINVVPDQPSERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDYTTDSEH", "length": 421 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0M6-1", "protein_name": "DUF1308 domain-containing protein", "gene_name": "CG13886", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEEQEDREKLYEEAHKKVKLGEELKKALKDFEDLPGVSKVQRKIQQELKFLNKVITTRSVKEHHITSSNFVYYDFLIKTLRLQQGVVDINAVFRLESRDSPLRVDIVANNGLKWVKVIARNSKSVEDAARGCVSIGARSVIDQAEDYLEASELSFCMFQRPKIVFYFSNKIEDSLHEELMEMGVQTASLDSPDTDLDMYATTSNELNLDVTTLLAYVSALTNGSANWVYKEPLLTEQAERERASPLKPLLEKILEGKTLVCCQLAYDAFQSILDIVGGEGERKRAEELMKRVTVYPDVETIPEEFSHIRFTANVNERSLKIFSFGMARQIFTVTSNKAFVRSAKMQGINVPVFVHASVALTEGKQATGRPL", "length": 371 }, "evidence": [ { "id": "A0A1D5P7R3", "url": "https://omabrowser.org/oma/group/A0A1D5P7R3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7R3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3" }, { "id": "PF07000", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1308", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 409, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5P7R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R3" }, { "id": "PF18474", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18474" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF5614", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 217, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PNL6-1", "uniprot_ac": "A0A1D5PNL6", "uniprot_id": "A0A1D5PNL6_CHICK", "mass": { "chemical_mass": 70905.0, "monoisotopic_mass": 70905.0 }, "refseq": { "ac": "XP_015137630", "name": "zinc finger MYND domain-containing protein 11 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137630" }, "gene_names": [ { "name": "ZMYND11", "type": "recommended", "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ] }, { "name": "ZMYND11", "type": "synonym", "evidence": [ { "id": "XP_015137630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137630" } ] } ], "protein_names": [ { "name": "Zinc finger MYND domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MYND domain-containing protein 11 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015137630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137630" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137630" } ] }, { "annotation": "Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6#function" }, { "database": "UniProtKB", "id": "ARBA00057630", "url": "https://www.uniprot.org/uniprotkb/ARBA00057630#function" }, { "database": "UniProtKB", "id": "E1BUC1", "url": "https://www.uniprot.org/uniprotkb/E1BUC1#function" }, { "database": "UniProtKB", "id": "A0A8V1A5I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I4#function" }, { "database": "UniProtKB", "id": "A0A8V1A353", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A353#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMYND11", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6", "locus": { "chromosome": "2", "start_pos": 9902165, "end_pos": 9799318, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025491", "url": "https://www.ensembl.org/id/ENSGALG00010025491" } ] } } ], "crossref": [ { "id": "A0A1D5PNL6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006599", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006599", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05492", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05492", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420455", "url": "https://www.ncbi.nlm.nih.gov/gene/420455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420455", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCHRVYH", "url": "https://omabrowser.org/oma/group/QCHRVYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNL6", "url": "https://www.orthodb.org/?gene=A0A1D5PNL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZXY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A353", "url": "https://www.orthodb.org/?gene=A0A8V1A353", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A368", "url": "https://www.orthodb.org/?gene=A0A8V1A368", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5I4", "url": "https://www.orthodb.org/?gene=A0A8V1A5I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BUC1", "url": "https://www.orthodb.org/?gene=E1BUC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46379:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46379:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BUC1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BUC1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_015137630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A353", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A353", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A353-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A353-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A368", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A368", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A368-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A368-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUC1", "url": "https://www.uniprot.org/uniprotkb/E1BUC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUC1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602, "header": "tr|A0A1D5PNL6-1|A0A1D5PNL6_CHICK Isoform 1 of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6/entry", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602, "header": "tr|A0A1D5PNL6-1|A0A1D5PNL6_CHICK Isoform 1 of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9841771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062226.1", "url": "https://www.ensembl.org/id/ENSGALT00010062226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038464.1", "url": "https://www.ensembl.org/id/ENSGALP00010038464.1" } ] } }, { "isoform_ac": "A0A8V0ZXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY4/entry", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEISIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 548, "header": "tr|A0A8V0ZXY4-1|A0A1D5PNL6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9841771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062222.1", "url": "https://www.ensembl.org/id/ENSGALT00010062222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038461.1", "url": "https://www.ensembl.org/id/ENSGALP00010038461.1" } ] } }, { "isoform_ac": "A0A8V1A353-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A353/entry", "sequence": { "sequence": "MYISILSPRRYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIAYGMQPFSQTAAKNKDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 588, "header": "tr|A0A8V1A353-1|A0A1D5PNL6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9843107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062212.1", "url": "https://www.ensembl.org/id/ENSGALT00010062212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038453.1", "url": "https://www.ensembl.org/id/ENSGALP00010038453.1" } ] } }, { "isoform_ac": "A0A8V1A368-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A368/entry", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIAYGMQPFSQTAAKNKSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 563, "header": "tr|A0A8V1A368-1|A0A1D5PNL6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9841771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062231.1", "url": "https://www.ensembl.org/id/ENSGALT00010062231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038468.1", "url": "https://www.ensembl.org/id/ENSGALP00010038468.1" } ] } }, { "isoform_ac": "A0A8V1A5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5I4/entry", "sequence": { "sequence": "MYISILSPRRYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIEVPVPSENQYKSSHCSEDLHATNDDNRRIHLIAYFRDDASFKLAYGMQPFSQTAAKNKDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 631, "header": "tr|A0A8V1A5I4-1|A0A1D5PNL6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=1 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9843107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062233.1", "url": "https://www.ensembl.org/id/ENSGALT00010062233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038470.1", "url": "https://www.ensembl.org/id/ENSGALP00010038470.1" } ] } }, { "isoform_ac": "E1BUC1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUC1/entry", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIAYGMQPFSQTAAKNKDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKNTSKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDKGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSMELKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPKMLHRSTQTNNDGVCQNMCHDKYTKIFNDFKDRMKADHKRETERVVREAVEKLRTEMEEEKRQAVSKAVANAQGEMDRKCKQVKEKCKEEFLEEIKKLAGQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 617, "header": "tr|E1BUC1-1|A0A1D5PNL6_CHICK Computationally mapped isoform of Zinc finger MYND domain-containing protein 11 OS=Gallus gallus OX=9031 GN=ZMYND11 PE=4 SV=2 CANONICAL=A0A1D5PNL6-1" }, "locus": { "chromosome": "2", "start_pos": 9899890, "end_pos": 9841771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062217.1", "url": "https://www.ensembl.org/id/ENSGALT00010062217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038457.1", "url": "https://www.ensembl.org/id/ENSGALP00010038457.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420455", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LJL9-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A1D5PNL6", "url": "https://omabrowser.org/oma/group/A0A1D5PNL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1SYN3-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEYRLRDSSSHWQCPVCRSIKKKNTNKQEMSTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPAIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSLCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A1D5PNL6", "url": "https://omabrowser.org/oma/group/A0A1D5PNL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7FKH2-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETETHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKHSNKQEMGTYLRFIVSRMKERAIDLNKKGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKATQEPRAKKGRRNQSVEPKKEVSCPPHSVQVAVERGKSLKVRSRQSSNIRQVKAQSPDSCRCGLLLDQHASAQSPSPEPEPETEAVSSSQEIPTMPQPIERVSVSTQTKKLSASSPRMLHRSTQTASDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLAAQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 658 }, "evidence": [ { "id": "A0A1D5PNL6", "url": "https://omabrowser.org/oma/group/A0A1D5PNL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15326-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "ZMYND11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSPWQCPVCRSIKKKNTNKQEMGTYLRFIVSRMKERAIDLNKKGKDNKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQVKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A1D5PNL6", "url": "https://omabrowser.org/oma/group/A0A1D5PNL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R5C8-1", "protein_name": "Zinc finger MYND domain-containing protein 11", "gene_name": "Zmynd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRVHGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETETHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKHSNKQEMGTYLRFIVSRMKERAIDLNKKGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQEPRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIERVSVSTQTKKLSASSPRMLHRSTQTTSDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVASLQGDMDRKGKQLKEKCKEEFVEEIKKLAAQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR", "length": 602 }, "evidence": [ { "id": "A0A1D5PNL6", "url": "https://omabrowser.org/oma/group/A0A1D5PNL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001237", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "histone H3 reader activity", "id": "GO:0140006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140006", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNL6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 238, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 563, "end_pos": 598, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 148, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 331, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNL6" }, { "id": "PS52014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAMD1-like winged helix (WH)", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 82, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 577, "end_pos": 579 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PY88-1", "uniprot_ac": "A0A1D5PY88", "uniprot_id": "A0A1D5PY88_CHICK", "mass": { "chemical_mass": 46504.0, "monoisotopic_mass": 46504.0 }, "refseq": { "ac": "XP_004934946", "name": "BTB/POZ domain-containing protein KCTD20 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934946" }, "gene_names": [ { "name": "KCTD20", "type": "recommended", "evidence": [ { "id": "A0A1D5PY88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88" } ] }, { "name": "KCTD20", "type": "synonym", "evidence": [ { "id": "XP_004934946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934946" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD20 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_004934946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934946" } ] }, { "name": "Potassium channel tetramerization domain containing 20", "type": "synonym", "evidence": [ { "id": "A0A1D5PY88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934946" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD20", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88", "locus": { "chromosome": "26", "start_pos": 1616059, "end_pos": 1580776, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024671", "url": "https://www.ensembl.org/id/ENSGALG00010024671" } ] } } ], "crossref": [ { "id": "A0A1D5PY88", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PY88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000511", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000511", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18386", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18386", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419814", "url": "https://www.ncbi.nlm.nih.gov/gene/419814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WNHEPFI", "url": "https://omabrowser.org/oma/group/WNHEPFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PY88", "url": "https://www.orthodb.org/?gene=A0A1D5PY88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU01", "url": "https://www.orthodb.org/?gene=A0A8V0ZU01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ55", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ61", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1C4", "url": "https://www.orthodb.org/?gene=A0A8V1A1C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3C5", "url": "https://www.orthodb.org/?gene=A0A8V1A3C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3E1", "url": "https://www.orthodb.org/?gene=A0A8V1A3E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PY88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVNCAGGRRNLESTCSVENGTVAVRETEEGNVVLGGHSPSAGLRNEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 412, "header": "tr|A0A1D5PY88-1|A0A1D5PY88_CHICK Isoform 1 of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PY88-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88/entry", "sequence": { "sequence": "MNVNCAGGRRNLESTCSVENGTVAVRETEEGNVVLGGHSPSAGLRNEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 412, "header": "tr|A0A1D5PY88-1|A0A1D5PY88_CHICK Isoform 1 of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1592737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060238.1", "url": "https://www.ensembl.org/id/ENSGALT00010060238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036998.1", "url": "https://www.ensembl.org/id/ENSGALP00010036998.1" } ] } }, { "isoform_ac": "A0A8V0ZU01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU01/entry", "sequence": { "sequence": "MPSSVPSHTEQDVFQLLEVSSSLRKRNQHLASRRPSMNVNCAGGRRNLESTCSVENGTVAVRETEEGNVVLGGHSPSAGLRNEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 448, "header": "tr|A0A8V0ZU01-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1587155, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060250.1", "url": "https://www.ensembl.org/id/ENSGALT00010060250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037010.1", "url": "https://www.ensembl.org/id/ENSGALP00010037010.1" } ] } }, { "isoform_ac": "A0A8V0ZZ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ55/entry", "sequence": { "sequence": "MQKGTKQSRREAWSRLQRASSSSLRKRNQHLASRRPSMNVNCAGGRRNLESTCSVENGTVAVRETEEGNVVLGGHSPSAGLRNEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 449, "header": "tr|A0A8V0ZZ55-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1590762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060242.1", "url": "https://www.ensembl.org/id/ENSGALT00010060242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037002.1", "url": "https://www.ensembl.org/id/ENSGALP00010037002.1" } ] } }, { "isoform_ac": "A0A8V0ZZ61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ61/entry", "sequence": { "sequence": "MSRHSSLRKRNQHLASRRPSMNVNCAGGRRNLESTCSVENGTVAVRETEEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 415, "header": "tr|A0A8V0ZZ61-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1588706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060247.1", "url": "https://www.ensembl.org/id/ENSGALT00010060247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037007.1", "url": "https://www.ensembl.org/id/ENSGALP00010037007.1" } ] } }, { "isoform_ac": "A0A8V1A1C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1C4/entry", "sequence": { "sequence": "MMFLSKLHLPFVCVSGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 380, "header": "tr|A0A8V1A1C4-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1593170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060244.1", "url": "https://www.ensembl.org/id/ENSGALT00010060244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037004.1", "url": "https://www.ensembl.org/id/ENSGALP00010037004.1" } ] } }, { "isoform_ac": "A0A8V1A3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3C5/entry", "sequence": { "sequence": "MSNLRRLSQEPGGRNSGCSSLRKRNQHLASRRPSMNVNCAGGRRNLESTCSVENGTVAVRETEEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 429, "header": "tr|A0A8V1A3C5-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1588365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060233.1", "url": "https://www.ensembl.org/id/ENSGALT00010060233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036993.1", "url": "https://www.ensembl.org/id/ENSGALP00010036993.1" } ] } }, { "isoform_ac": "A0A8V1A3E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E1/entry", "sequence": { "sequence": "MLNSWAICCTSQIQVLSSSLRKRNQHLASRRPSMNVNCAGGRRNLESTCSVENGTVAVRETEEGLDSDYRHTACPASPQFSSMLSASEDTHSCHFQDGNKRQTEYFNTQDRHAVSSSINSQTVAPEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIKCQDLSALLHELSNDGAHKQFDSYLEELILPIMVDSARKGERECHIVVLTDEDTVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKAVLKERGLKNIRIGIEGYPTCKEKVKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVTVGDDVSEDHEVIMHHPPQVDELDRLNAPFSQMAVNDLPD", "length": 428, "header": "tr|A0A8V1A3E1-1|A0A1D5PY88_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 20 OS=Gallus gallus OX=9031 GN=KCTD20 PE=4 SV=1 CANONICAL=A0A1D5PY88-1" }, "locus": { "chromosome": "26", "start_pos": 1597213, "end_pos": 1592558, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060248.1", "url": "https://www.ensembl.org/id/ENSGALT00010060248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037008.1", "url": "https://www.ensembl.org/id/ENSGALP00010037008.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RRY2-1", "protein_name": "Potassium channel tetramerization domain containing 20", "gene_name": "Kctd20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVHQGSDGDWLLQPELSFLGDETLAATQEKESSSLVSSGLPSLTYPLAARNEDFALDSAPQPAASLQHPHIMPLPEDNKGSCFQSGSRRSREPFLVPERSGSGGLGFGGSSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIMMHHPPQVDELDRLNAPLAQMAPNDFQD", "length": 418 }, "evidence": [ { "id": "A0A1D5PY88", "url": "https://omabrowser.org/oma/group/A0A1D5PY88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A4X1STM3-1", "protein_name": "Potassium channel tetramerization domain containing 20", "gene_name": "KCTD20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNAHRSTESDRSLRQEASCLMDEASAVAPEKEANILASSGLQTLAYPLGPRNDDLSLDYASQPANLQFPHMMPLPEDIKGSCFQSGNKRNHDPFIAPERFGNSTVGFGSNIHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEILMHHPPQVDELDRLNAPLSQMVSNDFQD", "length": 419 }, "evidence": [ { "id": "A0A1D5PY88", "url": "https://omabrowser.org/oma/group/A0A1D5PY88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HKB9-1", "protein_name": "BTB/POZ domain-containing protein KCTD20 isoform X1", "gene_name": "Kctd20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVHQGSDGDRVLQPELSCLGDETLAATQEKERKQQQLGVPWTSYSHSPLATRSEDFALEYASQPASLQHPPVMPLPEDSKGSCFQSGSKRSHEPFIVSERFGNSGVGFGGSPHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISAAVFRTVLDYYKTGVINCPDGISIPDLRDTCDYLCINFDSNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTLLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVATGEDVLEDQEIIMHHPPQVDELDRLNAPLSQMAPNDFQD", "length": 421 }, "evidence": [ { "id": "A0A1D5PY88", "url": "https://omabrowser.org/oma/group/A0A1D5PY88/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7Z5Y7-1", "protein_name": "BTB/POZ domain-containing protein KCTD20", "gene_name": "KCTD20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD", "length": 419 }, "evidence": [ { "id": "A0A1D5PY88", "url": "https://omabrowser.org/oma/group/A0A1D5PY88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDD8-1", "protein_name": "BTB/POZ domain-containing protein KCTD20", "gene_name": "Kctd20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVHQGSDGDWSLQPELSCLGDEALAATQEKEGSSLVSSGLHSVTYPLAARSEDLALDYASQPASLPHPHIMPLPEDNKGSCFQSGSKRSHEPFIVPERFGNSGLGFGGGAHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYVIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIIMHHPPQVDELDRLNAPLSQMAPNDFQD", "length": 419 }, "evidence": [ { "id": "A0A1D5PY88", "url": "https://omabrowser.org/oma/group/A0A1D5PY88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of phosphorylation", "id": "GO:0042327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042327", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PSH2-1", "uniprot_ac": "A0A1D5PSH2", "uniprot_id": "A0A1D5PSH2_CHICK", "mass": { "chemical_mass": 31383.0, "monoisotopic_mass": 31383.0 }, "refseq": { "ac": "XP_004947021", "name": "RNA-binding protein Raly isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947021" }, "gene_names": [ { "name": "RALY", "type": "recommended", "evidence": [ { "id": "A0A1D5PSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ] }, { "name": "RALY", "type": "synonym", "evidence": [ { "id": "XP_004947021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947021" } ] } ], "protein_names": [ { "name": "RALY heteroous nuclear ribonucleoprotein", "type": "synonym", "evidence": [ { "id": "A0A1D5PSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein Raly isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004947021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947021" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947021" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RALY", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2", "locus": { "chromosome": "20", "start_pos": 1998042, "end_pos": 2110990, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024769", "url": "https://www.ensembl.org/id/ENSGALG00010024769" } ] } } ], "crossref": [ { "id": "A0A1D5PSH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PSH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033696", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033696", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12604", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12604", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419148", "url": "https://www.ncbi.nlm.nih.gov/gene/419148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419148", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EDPHITA", "url": "https://omabrowser.org/oma/group/EDPHITA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSH2", "url": "https://www.orthodb.org/?gene=A0A1D5PSH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A216", "url": "https://www.orthodb.org/?gene=A0A8V1A216", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7A1", "url": "https://www.orthodb.org/?gene=A0A8V1A7A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947021", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A216", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A216", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A216-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A216-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVVGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPNRPKGLKRAASTLYSGYDFDYDYYRDDFYDRLFEYRGRVSPVPRVVPVKRPRVTIPLVRRVKATLPVKLFARSAAIANSSAKLKLKCSELQTIKTELTQIKSNIDALLGRLEQIAEEQKQSTEVRKKVDGSKSEVSQEDTASEAEVNTEEPLNGDEGEEEGLARDECEDELENSHYTDMEDARLQ", "length": 280, "header": "tr|A0A1D5PSH2-1|A0A1D5PSH2_CHICK Isoform 1 of RALY heteroous nuclear ribonucleoprotein OS=Gallus gallus OX=9031 GN=RALY PE=3 SV=3 CANONICAL=A0A1D5PSH2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2/entry", "sequence": { "sequence": "MSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVVGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPNRPKGLKRAASTLYSGYDFDYDYYRDDFYDRLFEYRGRVSPVPRVVPVKRPRVTIPLVRRVKATLPVKLFARSAAIANSSAKLKLKCSELQTIKTELTQIKSNIDALLGRLEQIAEEQKQSTEVRKKVDGSKSEVSQEDTASEAEVNTEEPLNGDEGEEEGLARDECEDELENSHYTDMEDARLQ", "length": 280, "header": "tr|A0A1D5PSH2-1|A0A1D5PSH2_CHICK Isoform 1 of RALY heteroous nuclear ribonucleoprotein OS=Gallus gallus OX=9031 GN=RALY PE=3 SV=3 CANONICAL=A0A1D5PSH2-1" }, "locus": { "chromosome": "20", "start_pos": 2018298, "end_pos": 1999943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060470.1", "url": "https://www.ensembl.org/id/ENSGALT00010060470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037229.1", "url": "https://www.ensembl.org/id/ENSGALP00010037229.1" } ] } }, { "isoform_ac": "A0A8V1A216-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A216/entry", "sequence": { "sequence": "MQVFKMSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVVGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPNRPKGLKRAASTLYSGYDFDYDYYRDDFYDRLFEYRGRVSPVPRVVPVKRPRVTIPLVRRVKATLPVKLFARSAAIANSSAKLKLKCSELQTIKTELTQIKSNIDALLGRLEQIAEEQKQSTEVRKKVDGSKSEVSQEDTASEAEVNTEEPLNGDEGEEEGLARDECEDELENSHYTDMEDARLQ", "length": 285, "header": "tr|A0A8V1A216-1|A0A1D5PSH2_CHICK Computationally mapped isoform of RALY heteroous nuclear ribonucleoprotein OS=Gallus gallus OX=9031 GN=RALY PE=3 SV=1 CANONICAL=A0A1D5PSH2-1" }, "locus": { "chromosome": "20", "start_pos": 2102596, "end_pos": 1999943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060471.1", "url": "https://www.ensembl.org/id/ENSGALT00010060471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037230.1", "url": "https://www.ensembl.org/id/ENSGALP00010037230.1" } ] } }, { "isoform_ac": "A0A8V1A7A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7A1/entry", "sequence": { "sequence": "MLDYAPIMVFTWAENSGVFKMSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVVGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPNRPKGLKRAASTLYSGYDFDYDYYRDDFYDRLFEYRGRVSPVPRVVPVKRPRVTIPLVRRVKATLPVKLFARSAAIANSSAKLKLKCSELQTIKTELTQIKSNIDALLGRLEQIAEEQKQSTEVRKKVDGSKSEVSQEDTASEAEVNTEEPLNGDEGEEEGLARDECEDELENSHYTDMEDARLQ", "length": 300, "header": "tr|A0A8V1A7A1-1|A0A1D5PSH2_CHICK Computationally mapped isoform of RALY heteroous nuclear ribonucleoprotein OS=Gallus gallus OX=9031 GN=RALY PE=3 SV=1 CANONICAL=A0A1D5PSH2-1" }, "locus": { "chromosome": "20", "start_pos": 2020123, "end_pos": 1999943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060468.1", "url": "https://www.ensembl.org/id/ENSGALT00010060468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037227.1", "url": "https://www.ensembl.org/id/ENSGALP00010037227.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QAY0-1", "protein_name": "RNA-binding protein Raly isoform X1", "gene_name": "raly", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLKVQTSNITNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVLGCSVHKGYAFVQYANERHARGAVIGENGRVLAGQTLDINMAGEPKPNRPKGLKRSAATLYSGYDFDYDYYRDDFYDRLFEYRGRVSPVPRAVPVKRPRVAVPVVRRVKSLPVKLLTRSAILPNSSVKHKLKSTELQAIKSELTQIKSNIDALLGRLDQITEDKYCSTELQKAEDLKSEASQDESGSESEDLQHSDVEEGEDHTHEECDDDMENNHISEMDPILQ", "length": 273 }, "evidence": [ { "id": "A0A1D5PSH2", "url": "https://omabrowser.org/oma/group/A0A1D5PSH2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PSH2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQL4-1", "uniprot_ac": "A0A1D5PQL4", "uniprot_id": "A0A1D5PQL4_CHICK", "mass": { "chemical_mass": 13116.0, "monoisotopic_mass": 13116.0 }, "refseq": { "ac": "NP_001034353", "name": "cyclin-dependent kinase 2-associated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" }, "gene_names": [ { "name": "CDK2AP1", "type": "recommended", "evidence": [ { "id": "A0A1D5PQL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4" } ] }, { "name": "CDK2AP1", "type": "synonym", "evidence": [ { "id": "NP_001034353", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase 2-associated protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PQL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4/entry#names_and_taxonomy" } ] }, { "name": "CDK2-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001034353", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" } ] }, { "name": "cyclin-dependent kinase 2-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001034353", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000766.1, DR412891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Jul 14, 2018 this sequence version replaced NP_001034353.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001034353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" } ] }, { "annotation": "Data suggest that cdk2ap1 may play a role in the sexual differentiation and development of gonad of chicken embryo.", "evidence": [ { "database": "RefSeq", "id": "NP_001034353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" }, { "database": "PubMed", "id": "19819846", "url": "https://glygen.org/publication/PubMed/19819846" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDK2AP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4", "locus": { "chromosome": "15", "start_pos": 5072390, "end_pos": 5057063, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024850", "url": "https://www.ensembl.org/id/ENSGALG00010024850" } ] } } ], "crossref": [ { "id": "A0A1D5PQL4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034919", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034919", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416826", "url": "https://www.ncbi.nlm.nih.gov/gene/416826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416826", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416826", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WMIYCIV", "url": "https://omabrowser.org/oma/group/WMIYCIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKZ7", "url": "https://www.orthodb.org/?gene=A0A1D5PKZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQL4", "url": "https://www.orthodb.org/?gene=A0A1D5PQL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2J7", "url": "https://www.orthodb.org/?gene=A0A8V1A2J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2K2", "url": "https://www.orthodb.org/?gene=A0A8V1A2K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4P6", "url": "https://www.orthodb.org/?gene=A0A8V1A4P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22607:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22607:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9937850", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001034353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGMSYKPNLNAHIPGTPLAPAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 122, "header": "tr|A0A1D5PQL4-1|A0A1D5PQL4_CHICK Isoform 1 of Cyclin-dependent kinase 2-associated protein OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKZ7/entry", "sequence": { "sequence": "MIYCIVGVNITDGHICRCRSCCKQPKVSGRRGDASLNSIRTPLLFPLAMSLGMSYKPNLNAHIPGTPLAPAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 170, "header": "tr|A0A1D5PKZ7-1|A0A1D5PKZ7_CHICK Computationally mapped isoform of Cyclin dependent kinase 2 associated protein 1 OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "locus": { "chromosome": "15", "start_pos": 5071599, "end_pos": 5058362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060674.1", "url": "https://www.ensembl.org/id/ENSGALT00010060674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037433.1", "url": "https://www.ensembl.org/id/ENSGALP00010037433.1" } ] } }, { "isoform_ac": "A0A1D5PQL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4/entry", "sequence": { "sequence": "MSLGMSYKPNLNAHIPGTPLAPAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 122, "header": "tr|A0A1D5PQL4-1|A0A1D5PQL4_CHICK Isoform 1 of Cyclin-dependent kinase 2-associated protein OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "locus": { "chromosome": "15", "start_pos": 5071599, "end_pos": 5058506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060675.1", "url": "https://www.ensembl.org/id/ENSGALT00010060675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037434.1", "url": "https://www.ensembl.org/id/ENSGALP00010037434.1" } ] } }, { "isoform_ac": "A0A8V1A2J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2J7/entry", "sequence": { "sequence": "MLHCFTFRQTICTDKVAGCAIFKCTANIREALIYLLVGNSVALALAGLEQAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 150, "header": "tr|A0A8V1A2J7-1|A0A1D5PQL4_CHICK Computationally mapped isoform of Cyclin-dependent kinase 2-associated protein OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "locus": { "chromosome": "15", "start_pos": 5071599, "end_pos": 5067509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060667.1", "url": "https://www.ensembl.org/id/ENSGALT00010060667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037426.1", "url": "https://www.ensembl.org/id/ENSGALP00010037426.1" } ] } }, { "isoform_ac": "A0A8V1A2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2K2/entry", "sequence": { "sequence": "MSLGMSYKPNLNAHIPGTPLAPAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGAIWLKEHVQV", "length": 111, "header": "tr|A0A8V1A2K2-1|A0A1D5PQL4_CHICK Computationally mapped isoform of Cyclin-dependent kinase 2-associated protein OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "locus": { "chromosome": "15", "start_pos": 5070277, "end_pos": 5058506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060672.1", "url": "https://www.ensembl.org/id/ENSGALT00010060672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037431.1", "url": "https://www.ensembl.org/id/ENSGALP00010037431.1" } ] } }, { "isoform_ac": "A0A8V1A4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P6/entry", "sequence": { "sequence": "DCRWPPPFWSLIPSRTRLLLYCADIECPRPGGETRGLLPNLGRRNPPPPSCRGEENRKSVPFGPRSALQKPLRVNAKRCGLSRPRALASSGSRRDFPLGAGSVHSPSTSMATSAQYRQLINDYGPPSLGYTQGIQGTSSSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 199, "header": "tr|A0A8V1A4P6-1|A0A1D5PQL4_CHICK Computationally mapped isoform of Cyclin-dependent kinase 2-associated protein OS=Gallus gallus OX=9031 GN=CDK2AP1 PE=1 SV=1 CANONICAL=A0A1D5PQL4-1" }, "locus": { "chromosome": "15", "start_pos": 5071599, "end_pos": 5060361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060671.1", "url": "https://www.ensembl.org/id/ENSGALT00010060671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037430.1", "url": "https://www.ensembl.org/id/ENSGALP00010037430.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "[Expression of cyclin-dependent kinase 2-associated protein 1 in chicken embryos of different sexes].", "journal": "Yi chuan = Hereditas", "date": "2009-09", "authors": "Yang Yu, Feng Yan-Ping, Gong Ping, Huang Pan, Li Shi-Jun, Peng Xiu-Li, Gong Yan-Zhang", "evidence": [ { "database": "RefSeq", "id": "NP_001034353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034353" } ], "reference": [ { "type": "PubMed", "id": "19819846", "url": "https://glygen.org/publication/PubMed/19819846" } ] } ], "pathway": [ { "id": "gga:416826", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416826", "resource": "KEGG Pathway" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RFL1-1", "protein_name": "Cyclin-dependent kinase 2-associated protein", "gene_name": "CDK2AP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSYKPNLTAHMPAASLNAAGSVHPPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 115 }, "evidence": [ { "id": "A0A1D5PQL4", "url": "https://omabrowser.org/oma/group/A0A1D5PQL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14519-1", "protein_name": "Cyclin-dependent kinase 2-associated protein 1", "gene_name": "CDK2AP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS", "length": 115 }, "evidence": [ { "id": "A0A1D5PQL4", "url": "https://omabrowser.org/oma/group/A0A1D5PQL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35207-1", "protein_name": "Cyclin-dependent kinase 2-associated protein 1", "gene_name": "Cdk2ap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYKPNLTAHMPAAALNAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARSLVRECLAETERNARS", "length": 114 }, "evidence": [ { "id": "A0A1D5PQL4", "url": "https://omabrowser.org/oma/group/A0A1D5PQL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RLN6-1", "uniprot_ac": "A0A1L1RLN6", "uniprot_id": "A0A1L1RLN6_CHICK", "mass": { "chemical_mass": 16838.0, "monoisotopic_mass": 16838.0 }, "refseq": {}, "gene_names": [ { "name": "MYL6", "type": "recommended", "evidence": [ { "id": "A0A1L1RLN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6" } ] } ], "protein_names": [ { "name": "Myosin, light chain 6, alkali, smooth muscle and non-muscle", "type": "synonym", "evidence": [ { "id": "A0A1L1RLN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLN6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYL6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6", "locus": { "chromosome": "34", "start_pos": 1419946, "end_pos": 1416077, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024882", "url": "https://www.ensembl.org/id/ENSGALG00010024882" } ] } } ], "crossref": [ { "id": "A0A1L1RLN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RLN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035086", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035086", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100996929", "url": "https://www.ncbi.nlm.nih.gov/gene/100996929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HDQASTN", "url": "https://omabrowser.org/oma/group/HDQASTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RLN6", "url": "https://www.orthodb.org/?gene=A0A1L1RLN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2T1", "url": "https://www.orthodb.org/?gene=A0A8V1A2T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2T6", "url": "https://www.orthodb.org/?gene=A0A8V1A2T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2U1", "url": "https://www.orthodb.org/?gene=A0A8V1A2U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A825", "url": "https://www.orthodb.org/?gene=A0A8V1A825", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5627123", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627123", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RLN6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RLN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2T1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A825", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A825", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A825-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A825-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "CDFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEAFVRHILSG", "length": 150, "header": "tr|A0A1L1RLN6-1|A0A1L1RLN6_CHICK Isoform 1 of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=2 CANONICAL=A0A1L1RLN6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RLN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLN6/entry", "sequence": { "sequence": "CDFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEAFVRHILSG", "length": 150, "header": "tr|A0A1L1RLN6-1|A0A1L1RLN6_CHICK Isoform 1 of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=2 CANONICAL=A0A1L1RLN6-1" }, "locus": { "chromosome": "34", "start_pos": 1419293, "end_pos": 1416343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060755.1", "url": "https://www.ensembl.org/id/ENSGALT00010060755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037514.1", "url": "https://www.ensembl.org/id/ENSGALP00010037514.1" } ] } }, { "isoform_ac": "A0A8V1A2T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T1/entry", "sequence": { "sequence": "MGWGGPIGRGGGGGGGCEVPPPLTSPPPPPTEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEELVRMVLSG", "length": 172, "header": "tr|A0A8V1A2T1-1|A0A1L1RLN6_CHICK Computationally mapped isoform of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=1 CANONICAL=A0A1L1RLN6-1" }, "locus": { "chromosome": "34", "start_pos": 1419745, "end_pos": 1417080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060752.1", "url": "https://www.ensembl.org/id/ENSGALT00010060752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037511.1", "url": "https://www.ensembl.org/id/ENSGALP00010037511.1" } ] } }, { "isoform_ac": "A0A8V1A2T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T6/entry", "sequence": { "sequence": "MEEMGECDFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEELVRMVLSG", "length": 156, "header": "tr|A0A8V1A2T6-1|A0A1L1RLN6_CHICK Computationally mapped isoform of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=1 CANONICAL=A0A1L1RLN6-1" }, "locus": { "chromosome": "34", "start_pos": 1419745, "end_pos": 1416185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060757.1", "url": "https://www.ensembl.org/id/ENSGALT00010060757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037516.1", "url": "https://www.ensembl.org/id/ENSGALP00010037516.1" } ] } }, { "isoform_ac": "A0A8V1A2U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2U1/entry", "sequence": { "sequence": "MCDFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEELVRMVLSG", "length": 138, "header": "tr|A0A8V1A2U1-1|A0A1L1RLN6_CHICK Computationally mapped isoform of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=1 CANONICAL=A0A1L1RLN6-1" }, "locus": { "chromosome": "34", "start_pos": 1419745, "end_pos": 1416132, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060762.1", "url": "https://www.ensembl.org/id/ENSGALT00010060762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037521.1", "url": "https://www.ensembl.org/id/ENSGALP00010037521.1" } ] } }, { "isoform_ac": "A0A8V1A825-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A825/entry", "sequence": { "sequence": "MCDFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLNFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEQLVAGHEDSNGCINYEELVRMVLSG", "length": 151, "header": "tr|A0A8V1A825-1|A0A1L1RLN6_CHICK Computationally mapped isoform of Myosin, light chain 6, alkali, smooth muscle and non-muscle OS=Gallus gallus OX=9031 GN=MYL6 PE=4 SV=1 CANONICAL=A0A1L1RLN6-1" }, "locus": { "chromosome": "34", "start_pos": 1419745, "end_pos": 1416132, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060759.1", "url": "https://www.ensembl.org/id/ENSGALT00010060759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037518.1", "url": "https://www.ensembl.org/id/ENSGALP00010037518.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" }, { "id": "R-GGA-5627123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627123", "resource": "Reactome", "description": "RHO GTPases activate PAKs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7J4R3-1", "protein_name": "Myosin light polypeptide 6 isoform X1", "gene_name": "Myl6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEGQCRTVNWSL", "length": 152 }, "evidence": [ { "id": "A0A1L1RLN6", "url": "https://omabrowser.org/oma/group/A0A1L1RLN6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53141-1", "protein_name": "Myosin light chain 1", "gene_name": "MLC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSATRANKDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLRQ", "length": 149 }, "evidence": [ { "id": "A0A1L1RLN6", "url": "https://omabrowser.org/oma/group/A0A1L1RLN6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54357-1", "protein_name": "Myosin-2 essential light chain", "gene_name": "Mlc-c", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAYTEDQLAEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDERISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEEFVRMVMSG", "length": 147 }, "evidence": [ { "id": "A0A1L1RLN6", "url": "https://omabrowser.org/oma/group/A0A1L1RLN6/", "database": "OMA" } ], "glygen_name": "Fruit 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"https://www.ncbi.nlm.nih.gov/protein/XP_415704" }, "gene_names": [ { "name": "NPLOC4", "type": "recommended", "evidence": [ { "id": "A0A1L1RME9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ] }, { "name": "NPLOC4", "type": "synonym", "evidence": [ { "id": "XP_415704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415704" } ] } ], "protein_names": [ { "name": "Nuclear protein localization protein 4 homolog", "type": "recommended", "evidence": [ { "id": "A0A1L1RME9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9/entry#names_and_taxonomy" } ] }, { "name": "nuclear protein localization protein 4 homolog", "type": "synonym", "evidence": [ { "id": "XP_415704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415704" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_415704.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415704" } ] }, { "annotation": "The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ADC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC7#function" }, { "database": "UniProtKB", "id": "ARBA00056115", "url": "https://www.uniprot.org/uniprotkb/ARBA00056115#function" }, { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPLOC4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9", "locus": { "chromosome": "18", "start_pos": 9808583, "end_pos": 9780732, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029515", "url": "https://www.ensembl.org/id/ENSGALG00010029515" } ] } } ], "crossref": [ { "id": "A0A1L1RME9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RME9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004583", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004583", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417456", "url": "https://www.ncbi.nlm.nih.gov/gene/417456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" 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"categories": [ "Protein Classification" ] }, { "id": "KWSRTGR", "url": "https://omabrowser.org/oma/group/KWSRTGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RME9", "url": "https://www.orthodb.org/?gene=A0A1L1RME9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADC7", "url": "https://www.orthodb.org/?gene=A0A8V1ADC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMG7", "url": "https://www.orthodb.org/?gene=A0A8V1AMG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12710:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12710:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11543", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11543", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-110320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9755511", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETIIIRVQSPEGVKRITATKRETVATFLKKVAKEFGFRNNGFSVYTNRNRTGEITASQNKSLNLLKIKHGDMLFLYPSSPAGSSSETMDTSVSQGLRPVGAPQVVEDDIDQYLIKQDGKIYRNRDQQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIMFENHTIADRFLDFWRKTGNQHLGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLEILEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYYLSAEECITAGNFQNQHPNICRLSPDGHFGSKFVTVVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCRDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDIVSDFHLLLFLVTNEVMPLRDSISLLLEAVRTKNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEYGAVGGSTHAVSAAMWACQHCTFMNQPGTDHCEMCSLPRT", "length": 609, "header": "tr|A0A1L1RME9-1|A0A1L1RME9_CHICK Isoform 1 of Nuclear protein localization protein 4 homolog OS=Gallus gallus OX=9031 GN=NPLOC4 PE=1 SV=2 CANONICAL=A0A1L1RME9-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9/entry", "sequence": { "sequence": "MAETIIIRVQSPEGVKRITATKRETVATFLKKVAKEFGFRNNGFSVYTNRNRTGEITASQNKSLNLLKIKHGDMLFLYPSSPAGSSSETMDTSVSQGLRPVGAPQVVEDDIDQYLIKQDGKIYRNRDQQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIMFENHTIADRFLDFWRKTGNQHLGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLEILEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYYLSAEECITAGNFQNQHPNICRLSPDGHFGSKFVTVVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCRDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDIVSDFHLLLFLVTNEVMPLRDSISLLLEAVRTKNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEYGAVGGSTHAVSAAMWACQHCTFMNQPGTDHCEMCSLPRT", "length": 609, "header": "tr|A0A1L1RME9-1|A0A1L1RME9_CHICK Isoform 1 of Nuclear protein localization protein 4 homolog OS=Gallus gallus OX=9031 GN=NPLOC4 PE=1 SV=2 CANONICAL=A0A1L1RME9-1" }, "locus": { "chromosome": "18", "start_pos": 9807330, "end_pos": 9780959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071342.1", "url": "https://www.ensembl.org/id/ENSGALT00010071342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044033.1", "url": "https://www.ensembl.org/id/ENSGALP00010044033.1" } ] } }, { "isoform_ac": "A0A8V1ADC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC7/entry", "sequence": { "sequence": "MAETICPSVALLCISVLVCPVLRKARAPRFIFAPSQALILPRLLLVFFHLQLKAAAELMIIRVQSPEGVKRITATKRETVATFLKKVAKEFGFRNNGFSVYTNRNRTGEITASQNKSLNLLKIKHGDMLFLYPSSPAGSSSETMDTSVSQGLRPVGAPQVVEDDIDQYLIKQDGKIYRNRDQQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIMFENHTIADRFLDFWRKTGNQHLGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLEILEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYYLSAEECITAGNFQNQHPNICRLSPDGHFGSKFVTVVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCRDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDIVSDFHLLLFLVTNEVMPLRDSISLLLEAVRTKNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEYGAVGGSTHAVSAAMWACQHCTFMNQPGTDHCEMCSLPRT", "length": 663, "header": "tr|A0A8V1ADC7-1|A0A1L1RME9_CHICK Computationally mapped isoform of Nuclear protein localization protein 4 homolog OS=Gallus gallus OX=9031 GN=NPLOC4 PE=1 SV=1 CANONICAL=A0A1L1RME9-1" }, "locus": { "chromosome": "18", "start_pos": 9807330, "end_pos": 9780959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071343.1", "url": "https://www.ensembl.org/id/ENSGALT00010071343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044034.1", "url": "https://www.ensembl.org/id/ENSGALP00010044034.1" } ] } }, { "isoform_ac": "A0A8V1AMG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG7/entry", "sequence": { "sequence": "MAETIIIRVQSPEGVKRITATKRETVATFLKKVAKEFGFRNNGFSVYTNRNRTGEITASQNKSLNLLKIKHGDMLFLYPSSPAGSSSETMDTSVSQGLRPVGAPQVVEDDIDQYLIKQDGKIYRNRDQQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIMFENHTIADRFLDFWRKTGNQHLGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLEILEDPKAEVVDEIAAKLGLRKDTYYLSAEECITAGNFQNQHPNICRLSPDGHFGSKFVTVVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCRDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDIVSDFHLLLFLVTNEVMPLRDSISLLLEAVRTKNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEYGAVGGSTHAVSAAMWACQHCTFMNQPGTDHCEMCSLPRT", "length": 585, "header": "tr|A0A8V1AMG7-1|A0A1L1RME9_CHICK Computationally mapped isoform of Nuclear protein localization protein 4 homolog OS=Gallus gallus OX=9031 GN=NPLOC4 PE=1 SV=1 CANONICAL=A0A1L1RME9-1" }, "locus": { "chromosome": "18", "start_pos": 9807330, "end_pos": 9780959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071341.1", "url": "https://www.ensembl.org/id/ENSGALT00010071341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044032.1", "url": "https://www.ensembl.org/id/ENSGALP00010044032.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-110320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110320", "resource": "Reactome", "description": "Translesion Synthesis by POLH" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P33755-1", "protein_name": "Nuclear protein localization protein 4", "gene_name": "NPL4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLIRFRSKNGTHRVSCQENDLFGTVIEKLVGNLDPNADVDTFTVCEKPGQGIHAVSELADRTVMDLGLKHGDMLILNYSDKPANEKDGVNVEIGSVGIDSKGIRQHRYGPLRIKELAVDEELEKEDGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEKNKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPWPRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARHQTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTADMISGSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVKENAKPAFPVDYLLVTLTHGFPNTDTETNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASSGDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSSAGWQTLVMILQESG", "length": 580 }, "evidence": [ { "id": "A0A1L1RME9", "url": "https://omabrowser.org/oma/group/A0A1L1RME9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P60670-1", "protein_name": "Nuclear protein localization protein 4 homolog", "gene_name": "Nploc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSSKSLHLLKIKHGDLLFLFPSSLAGPSSEMETSTSVGLKAFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNICRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEFGAVGGSARAATSAMWACQHCTFMNQPGTGHCEMCSLPRT", "length": 608 }, "evidence": [ { "id": "A0A1L1RME9", "url": "https://omabrowser.org/oma/group/A0A1L1RME9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAT6-1", "protein_name": "Nuclear protein localization protein 4 homolog", "gene_name": "NPLOC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNMCRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQLPGLHEYGAVGGSTHTATAAMWACQHCTFMNQPGTGHCEMCSLPRT", "length": 608 }, "evidence": [ { "id": "A0A1L1RME9", "url": "https://omabrowser.org/oma/group/A0A1L1RME9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ES54-1", "protein_name": "Nuclear protein localization protein 4 homolog", "gene_name": "Nploc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSSKSLHLLKIKHGDLLFLFPSSLAGPSSEMETSTSVGLKAFGAPHVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIASKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNICRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEFGAVGGSARAATSAMWACQHCTFMNQPGTGHCEMCSLPRT", "length": 608 }, "evidence": [ { "id": "A0A1L1RME9", "url": "https://omabrowser.org/oma/group/A0A1L1RME9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VBP9-1", "protein_name": "Nuclear protein localization protein 4 homolog", "gene_name": "Npl4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MACAPLLLEQFIYKKRNFAYAFVRHRLFVLCKQSLIRVQSAEGIKRIEISPKSNLKHLYDSVQNALKVDGFGLFKERNFLTELQASGSQLVGTSLRHGDMVYLKQMAGTSSRRTSTTVLDSQAFKTSTISNPNSARPSFNVIEDDVDQALSKADGTIKRERDSKLCHHNANGRCVHCSALEPYDESYLKEHNIKHLSFHSYIRKQTSGMDQGKYFVFDDINCRIKPGCREHPPWPKGICSKCQPSAITLNRQTYRHVDNVMFENTKIVERFLNYWRTTGHQRMGYLYGTYEQHTDVPLGIRAKVAAIYEPPQESTRDSINIQPDEFADDVDAVASALGLKKIGWIFTDLITDDASIGTVKQIRGIESHFITAQECITAGELQNRHPNPCKYASNGVFGSKFVTICVTGDKTKQVHMEGYAVSAQCMALVRDNCLIPTKDAPELGYVRESTDKQYVPDVFYKEKDLYGNEVQRLARPLPVEYLLVDVPASTPLQPIYTFTEYDKRQPFPIENRYIDGHLQDFNALSCYLSAWGEEEFLEAISDFHLLVYLYKMDMLPLRQHMGPLLEAVRTKNPNQAAQFKVVDVWKLLESLIQASSGGSGGTTSYPSGGASASAGASGSEAMDLDANTWTCNHCTFINRGELTSCEICSLPR", "length": 652 }, "evidence": [ { "id": "A0A1L1RME9", "url": "https://omabrowser.org/oma/group/A0A1L1RME9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "VCP-NPL4-UFD1 AAA ATPase complex", "id": "GO:0034098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034098", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "UFD1-NPL4 complex", "id": "GO:0036501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036501", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "negative regulation of RIG-I signaling pathway", "id": "GO:0039536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039536", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RME9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RME9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PP06-1", "uniprot_ac": "A0A1D5PP06", "uniprot_id": "A0A1D5PP06_CHICK", "mass": { "chemical_mass": 75330.0, "monoisotopic_mass": 75330.0 }, "refseq": { "ac": "NP_001239092", "name": "armadillo repeat-containing protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239092" }, "gene_names": [ { "name": "ARMC8", "type": "recommended", "evidence": [ { "id": "A0A1D5PP06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ] }, { "name": "ARMC8", "type": "synonym", "evidence": [ { "id": "NP_001239092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239092" } ] } ], "protein_names": [ { "name": "Armadillo repeat-containing protein 8", "type": "recommended", "evidence": [ { "id": "A0A1D5PP06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 8", "type": "synonym", "evidence": [ { "id": "NP_001239092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239092" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01051721.1, SRR13267648.26064.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000240.1. On Nov 6, 2011 this sequence version replaced XP_422554.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239092" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARMC8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06", "locus": { "chromosome": "9", "start_pos": 129903, "end_pos": 192296, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022644", "url": "https://www.ensembl.org/id/ENSGALG00010022644" } ] } } ], "crossref": [ { "id": "A0A1D5PP06", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PP06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040889", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040889", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424731", "url": "https://www.ncbi.nlm.nih.gov/gene/424731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424731", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424731", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGTDQHV", "url": "https://omabrowser.org/oma/group/KGTDQHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PP06", "url": "https://www.orthodb.org/?gene=A0A1D5PP06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIZ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR82", "url": "https://www.orthodb.org/?gene=A0A8V0ZR82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR97", "url": "https://www.orthodb.org/?gene=A0A8V0ZR97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS10", "url": "https://www.orthodb.org/?gene=A0A8V0ZS10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWT2", "url": "https://www.orthodb.org/?gene=A0A8V0ZWT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15651", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15651", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15651:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15651:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9861718", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9861718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001239092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PP06-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACVLEAPLRMSVLSEVTASSRHYVDRLFDLDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 673, "header": "tr|A0A1D5PP06-1|A0A1D5PP06_CHICK Isoform 1 of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PP06-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06/entry", "sequence": { "sequence": "MACVLEAPLRMSVLSEVTASSRHYVDRLFDLDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 673, "header": "tr|A0A1D5PP06-1|A0A1D5PP06_CHICK Isoform 1 of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 192177, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055138.1", "url": "https://www.ensembl.org/id/ENSGALT00010055138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033353.1", "url": "https://www.ensembl.org/id/ENSGALP00010033353.1" } ] } }, { "isoform_ac": "A0A8V0ZIZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ2/entry", "sequence": { "sequence": "MRCGILSQALQKSRDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 646, "header": "tr|A0A8V0ZIZ2-1|A0A8V0ZIZ2_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 176372, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055095.1", "url": "https://www.ensembl.org/id/ENSGALT00010055095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033317.1", "url": "https://www.ensembl.org/id/ENSGALP00010033317.1" } ] } }, { "isoform_ac": "A0A8V0ZIZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ8/entry", "sequence": { "sequence": "MAFWSWLLRDLLPGRGEIVHNGCPASRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCYSKFWWLIFGLQYLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 648, "header": "tr|A0A8V0ZIZ8-1|A0A8V0ZIZ8_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 166595, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055102.1", "url": "https://www.ensembl.org/id/ENSGALT00010055102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033322.1", "url": "https://www.ensembl.org/id/ENSGALP00010033322.1" } ] } }, { "isoform_ac": "A0A8V0ZPB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB8/entry", "sequence": { "sequence": "MKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 631, "header": "tr|A0A8V0ZPB8-1|A0A8V0ZPB8_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 175292, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055105.1", "url": "https://www.ensembl.org/id/ENSGALT00010055105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033324.1", "url": "https://www.ensembl.org/id/ENSGALP00010033324.1" } ] } }, { "isoform_ac": "A0A8V0ZPC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC3/entry", "sequence": { "sequence": "MACVLEAPLRMSVLSEVTASSRHYVDRLFDLDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 644, "header": "tr|A0A8V0ZPC3-1|A0A8V0ZPC3_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 192177, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055111.1", "url": "https://www.ensembl.org/id/ENSGALT00010055111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033329.1", "url": "https://www.ensembl.org/id/ENSGALP00010033329.1" } ] } }, { "isoform_ac": "A0A8V0ZR82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR82/entry", "sequence": { "sequence": "MACVLEAPLRMSVLSVTASSRHYVDRLFDLDPQKVLQGVMLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKENMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 617, "header": "tr|A0A8V0ZR82-1|A0A8V0ZR82_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 192177, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055125.1", "url": "https://www.ensembl.org/id/ENSGALT00010055125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033341.1", "url": "https://www.ensembl.org/id/ENSGALP00010033341.1" } ] } }, { "isoform_ac": "A0A8V0ZR97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR97/entry", "sequence": { "sequence": "MACVLEAPLRMSVLSEVTASSRHYVDRLFDLDPQKVLQGVMLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 649, "header": "tr|A0A8V0ZR97-1|A0A8V0ZR97_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 192177, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055142.1", "url": "https://www.ensembl.org/id/ENSGALT00010055142.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033356.1", "url": "https://www.ensembl.org/id/ENSGALP00010033356.1" } ] } }, { "isoform_ac": "A0A8V0ZS10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS10/entry", "sequence": { "sequence": "MACVLEAPLRMSVLSEVTASSRHYVDRLFDLDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQESSSTELRTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKLQHWHSCGFKSLPQPLLCANGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 693, "header": "tr|A0A8V0ZS10-1|A0A1D5PP06_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 192177, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055135.1", "url": "https://www.ensembl.org/id/ENSGALT00010055135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033350.1", "url": "https://www.ensembl.org/id/ENSGALP00010033350.1" } ] } }, { "isoform_ac": "A0A8V0ZWT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWT2/entry", "sequence": { "sequence": "MSTDCLTWIPRKSCKVSYMKNAVIGNNKQKANLIVLGAVPSVPSASFHVIRRNHLDPKSLFMFLSLSAKENGLLSPDLKFIEACLRCLRTVFISPVTPEDLLYTDATVISHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLVSSSYKVRMQALKCFSVLAFENPQVSMTLVNVSVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTSMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIETDVELQRIASITDHLIVMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVNGLSESSIKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPNEILIVASSTLCNLLLEFSPSKEPILESGAIELLCSLTQSENLALRVNGIWALMNMAFQAEQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDHIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMSHSNAKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSSDPNLCDKAKTALQQYLA", "length": 632, "header": "tr|A0A8V0ZWT2-1|A0A1D5PP06_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Gallus gallus OX=9031 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A1D5PP06-1" }, "locus": { "chromosome": "9", "start_pos": 189956, "end_pos": 132411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055117.1", "url": "https://www.ensembl.org/id/ENSGALT00010055117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033333.1", "url": "https://www.ensembl.org/id/ENSGALP00010033333.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424731", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424731", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9861718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9861718", "resource": "Reactome", "description": "Regulation of pyruvate metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M943-1", "protein_name": "Armadillo repeat-containing protein 8", "gene_name": "Armc8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQEASSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDMNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHSMEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSTDSNLCDKAKTALQQYLA", "length": 673 }, "evidence": [ { "id": "A0A1D5PP06", "url": "https://omabrowser.org/oma/group/A0A1D5PP06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HEX6-1", "protein_name": "Armadillo repeat-containing protein 8", "gene_name": "Armc8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHSIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKTALQQYLA", "length": 673 }, "evidence": [ { "id": "A0A1D5PP06", "url": "https://omabrowser.org/oma/group/A0A1D5PP06/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q55D97-1", "protein_name": "Armadillo repeat-containing protein", "gene_name": "armc8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNTPLYTLDENCKQSLNILNPENRGIYNDETRIQSAKFIKNTIIGNKLKKRLFIEAGTIPLFVDILNKEKNEDLLIQASSVIGSFGCRIDEGSEKIFEYNGVTPLINLLSSNNLKLVESAARSLKILSLFHQPPTSIYEESGVKLLISLFNHPLDSVKEVAATIIARGCESLYSNNNNNNNNNNNNNNNNNNNNNNNNNTNIGNSSIISSGSSSSSSSNSINHSLLQYQNFVHIHGGLNSVMSILASPRSKIQEACLYVISWLTRDNVPLSTFIVNDERRILDIIIYLFKKNKSPKIKLLATNCLCNFNQSKTLPITCSLKNILPIIIRLMSEEESVKEEAPMVLARLVADNEDLQRIASEAEAISRLSIFLKDSNSSERLKENSLSAIAVLCSSREDSRKQVVDAKIIPQIISSLNSSNYAIRAAACNCTKSLSRSIKQLRTSLFDCTIATPLLKLLDDQSLEVRVSASATLCNLVLDFSPMKQAIMDNGIIVKLVDLTQDSNDFKIRLNCIWALKNLLYMAEPSLKEQVMKELGYQRLIELIKDTDPSISEQALAVLRNLAFKDNDHLISELHFHDQLVPTIENRLASNIPEIIKQTLFVICNIAGNEKIRSSVMNSSIVNRLIHFMEHKHCEIRIASVWCVCNIIGPDENSTSASRVLKFKELGYQKKLEMLADHDSNIEVKDRVKTALTLFKKCVFL", "length": 702 }, "evidence": [ { "id": "A0A1D5PP06", "url": "https://omabrowser.org/oma/group/A0A1D5PP06/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IUR7-1", "protein_name": "Armadillo repeat-containing protein 8", "gene_name": "ARMC8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA", "length": 673 }, "evidence": [ { "id": "A0A1D5PP06", "url": "https://omabrowser.org/oma/group/A0A1D5PP06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBR3-1", "protein_name": "Armadillo repeat-containing protein 8", "gene_name": "Armc8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETETMMDRIVTGSSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDMNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHSIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLTWNEEEGSQERQDKLRDMGIVDILHKLSQSADSNLCDKAKTALQQYLA", "length": 673 }, "evidence": [ { "id": "A0A1D5PP06", "url": "https://omabrowser.org/oma/group/A0A1D5PP06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP06", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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}, "gene_names": [ { "name": "TEAD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PMA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ] }, { "name": "TEAD1", "type": "synonym", "evidence": [ { "id": "XP_015141828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141828" } ] } ], "protein_names": [ { "name": "TEA domain transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PMA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2/entry#names_and_taxonomy" } ] }, { "name": "transcriptional enhancer factor TEF-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141828" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141828" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEAD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2", "locus": { "chromosome": "5", "start_pos": 7416439, "end_pos": 7556957, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021812", "url": "https://www.ensembl.org/id/ENSGALG00010021812" } ] } } ], "crossref": [ { "id": "A0A1D5PMA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PMA2", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SIWQPGL", "url": "https://omabrowser.org/oma/group/SIWQPGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PAU3", "url": "https://www.orthodb.org/?gene=A0A1D5PAU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMA2", "url": "https://www.orthodb.org/?gene=A0A1D5PMA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFB4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ3", "database": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF01285", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2032785", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2032785", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951671", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951671", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PAU3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP8-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 433, "header": "tr|A0A1D5PMA2-1|A0A1D5PMA2_CHICK Isoform 1 of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAU3/entry", "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 412, "header": "tr|A0A1D5PAU3-1|A0A1D5PAU3_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505075, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053082.1", "url": "https://www.ensembl.org/id/ENSGALT00010053082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031972.1", "url": "https://www.ensembl.org/id/ENSGALP00010031972.1" } ] } }, { "isoform_ac": "A0A1D5PMA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2/entry", "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 433, "header": "tr|A0A1D5PMA2-1|A0A1D5PMA2_CHICK Isoform 1 of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505075, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053072.1", "url": "https://www.ensembl.org/id/ENSGALT00010053072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031965.1", "url": "https://www.ensembl.org/id/ENSGALP00010031965.1" } ] } }, { "isoform_ac": "A0A8V0ZFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB4/entry", "sequence": { "sequence": "MPVRFISFKTPSLSLETPAITIEPSSWSGSESPAEDIERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 447, "header": "tr|A0A8V0ZFB4-1|A0A8V0ZFB4_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7513283, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053101.1", "url": "https://www.ensembl.org/id/ENSGALT00010053101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031986.1", "url": "https://www.ensembl.org/id/ENSGALP00010031986.1" } ] } }, { "isoform_ac": "A0A8V0ZKQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ2/entry", "sequence": { "sequence": "MPRGLVCLFCRFISFKTPSLSLETPAITIEPSSWSGSESPAEDIERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 458, "header": "tr|A0A8V0ZKQ2-1|A0A8V0ZKQ2_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505213, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053092.1", "url": "https://www.ensembl.org/id/ENSGALT00010053092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031978.1", "url": "https://www.ensembl.org/id/ENSGALP00010031978.1" } ] } }, { "isoform_ac": "A0A8V0ZMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP8/entry", "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKTTLQDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 433, "header": "tr|A0A8V0ZMP8-1|A0A8V0ZMP8_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505075, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053077.1", "url": "https://www.ensembl.org/id/ENSGALT00010053077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031969.1", "url": "https://www.ensembl.org/id/ENSGALP00010031969.1" } ] } }, { "isoform_ac": "A0A8V0ZMQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ3/entry", "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKTTLQDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 412, "header": "tr|A0A8V0ZMQ3-1|A0A8V0ZMQ3_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505075, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053086.1", "url": "https://www.ensembl.org/id/ENSGALT00010053086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031974.1", "url": "https://www.ensembl.org/id/ENSGALP00010031974.1" } ] } }, { "isoform_ac": "A0A8V0ZT25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT25/entry", "sequence": { "sequence": "MQPCFYPWCNTEVTGVTVGVGLATGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 387, "header": "tr|A0A8V0ZT25-1|A0A1D5PMA2_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7501410, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053068.1", "url": "https://www.ensembl.org/id/ENSGALT00010053068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031962.1", "url": "https://www.ensembl.org/id/ENSGALP00010031962.1" } ] } }, { "isoform_ac": "A0A8V0ZT47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT47/entry", "sequence": { "sequence": "MPRGLVCLFCRFISFKTPSLSLETPAITIEPSSWSGSESPAEDIERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 454, "header": "tr|A0A8V0ZT47-1|A0A1D5PMA2_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505213, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053097.1", "url": "https://www.ensembl.org/id/ENSGALT00010053097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031982.1", "url": "https://www.ensembl.org/id/ENSGALP00010031982.1" } ] } }, { "isoform_ac": "A0A8V0ZT57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT57/entry", "sequence": { "sequence": "MWSACTLRHLFERIYYLPSCANWAGFRFISFKTPSLSLETPAITIEPSSWSGSESPAEDIERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 470, "header": "tr|A0A8V0ZT57-1|A0A1D5PMA2_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7546821, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053110.1", "url": "https://www.ensembl.org/id/ENSGALT00010053110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031992.1", "url": "https://www.ensembl.org/id/ENSGALP00010031992.1" } ] } }, { "isoform_ac": "A0A8V0ZT62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT62/entry", "sequence": { "sequence": "MSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGKNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPSVTAPISGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPESYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDTGAFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 408, "header": "tr|A0A8V0ZT62-1|A0A1D5PMA2_CHICK Computationally mapped isoform of TEA domain transcription factor 1 OS=Gallus gallus OX=9031 GN=TEAD1 PE=1 SV=1 CANONICAL=A0A1D5PMA2-1" }, "locus": { "chromosome": "5", "start_pos": 7505075, "end_pos": 7418891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053117.1", "url": "https://www.ensembl.org/id/ENSGALT00010053117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031997.1", "url": "https://www.ensembl.org/id/ENSGALP00010031997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2032785", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2032785", "resource": "Reactome", "description": "YAP1- and WWTR1 (TAZ)-stimulated gene expression" }, { "id": "R-GGA-8951671", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951671", "resource": "Reactome", "description": "RUNX3 regulates YAP1-mediated transcription" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TQS6-1", "protein_name": "TEA domain transcription factor 1", "gene_name": "TEAD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 432 }, "evidence": [ { "id": "A0A1D5PMA2", "url": "https://omabrowser.org/oma/group/A0A1D5PMA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M0F3-1", "protein_name": "Transcriptional enhancer factor TEF-1 isoform X1", "gene_name": "Tead1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 436 }, "evidence": [ { "id": "A0A1D5PMA2", "url": "https://omabrowser.org/oma/group/A0A1D5PMA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P28347-1", "protein_name": "Transcriptional enhancer factor TEF-1", "gene_name": "TEAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "length": 426 }, "evidence": [ { "id": "A0A1D5PMA2", "url": "https://omabrowser.org/oma/group/A0A1D5PMA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "TEAD-YAP complex", "id": "GO:0140552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140552", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 391, "end_pos": 393 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PL96-1", "uniprot_ac": "A0A1D5PL96", "uniprot_id": "A0A1D5PL96_CHICK", "mass": { "chemical_mass": 32357.0, "monoisotopic_mass": 32357.0 }, "refseq": { "ac": "XP_004938861", "name": "gamma-sarcoglycan isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938861" }, "gene_names": [ { "name": "SGCG", "type": "recommended", "evidence": [ { "id": "A0A1D5PL96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ] }, { "name": "SGCG", "type": "synonym", "evidence": [ { "id": "XP_004938861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938861" } ] } ], "protein_names": [ { "name": "Gamma-sarcoglycan", "type": "recommended", "evidence": [ { "id": "A0A1D5PL96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96/entry#names_and_taxonomy" } ] }, { "name": "gamma-sarcoglycan isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004938861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938861" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938861" } ] }, { "annotation": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XXF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXF1#function" }, { "database": "UniProtKB", "id": "ARBA00002860", "url": "https://www.uniprot.org/uniprotkb/ARBA00002860#function" }, { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGCG", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96", "locus": { "chromosome": "1", "start_pos": 177528420, "end_pos": 177644356, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006220", "url": "https://www.ensembl.org/id/ENSGALG00010006220" } ] } } ], "crossref": [ { "id": "A0A1D5PL96", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PL96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017122", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017122", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418945", "url": "https://www.ncbi.nlm.nih.gov/gene/418945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418945", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418945", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMWFSPV", "url": "https://omabrowser.org/oma/group/VMWFSPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PL96", "url": "https://www.orthodb.org/?gene=A0A1D5PL96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXF1", "url": "https://www.orthodb.org/?gene=A0A8V0XXF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938861", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVREQYTTTTPGTSLERPKNEYVYKIGIYGWRKRCLYLFVLLLLIILVVNFSLTIWILKVMWFSPTGMGHLRVTKEGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTHNVTVNARNSNGEVTGRLNVGPKMVEFHGQQFQINSKDGKPLFTVDENEVVIGTDKLRVTGPEGALFEHSVETPLVKAEAFKQLRLESPTRSLSMDAPRGINIKAQAGNIEALSQMDIKLHSSDGVLLLDAETVRLPKLPEGTRGGPGVSQGLYEICVCPDGKLYLSVAGLGSTCQEYSRVCQ", "length": 291, "header": "tr|A0A1D5PL96-1|A0A1D5PL96_CHICK Isoform 1 of Gamma-sarcoglycan OS=Gallus gallus OX=9031 GN=SGCG PE=1 SV=1 CANONICAL=A0A1D5PL96-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96/entry", "sequence": { "sequence": "MVREQYTTTTPGTSLERPKNEYVYKIGIYGWRKRCLYLFVLLLLIILVVNFSLTIWILKVMWFSPTGMGHLRVTKEGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTHNVTVNARNSNGEVTGRLNVGPKMVEFHGQQFQINSKDGKPLFTVDENEVVIGTDKLRVTGPEGALFEHSVETPLVKAEAFKQLRLESPTRSLSMDAPRGINIKAQAGNIEALSQMDIKLHSSDGVLLLDAETVRLPKLPEGTRGGPGVSQGLYEICVCPDGKLYLSVAGLGSTCQEYSRVCQ", "length": 291, "header": "tr|A0A1D5PL96-1|A0A1D5PL96_CHICK Isoform 1 of Gamma-sarcoglycan OS=Gallus gallus OX=9031 GN=SGCG PE=1 SV=1 CANONICAL=A0A1D5PL96-1" }, "locus": { "chromosome": "1", "start_pos": 177591396, "end_pos": 177531898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014813.1", "url": "https://www.ensembl.org/id/ENSGALT00010014813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008726.1", "url": "https://www.ensembl.org/id/ENSGALP00010008726.1" } ] } }, { "isoform_ac": "A0A8V0XXF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXF1/entry", "sequence": { "sequence": "MVREQYTTTTPGTSLERPKNEYVYKIGIYGWRKRCLYLFVLLLLIILVVNFSLTIWILKVMWFSPADIYCWKRDIPPGPSGVFWIFLVLRDSVLLLSSGRNGRTFPDLVDILDISIGFLENTTASLLFQTGMGHLRVTKEGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTHNVTVNARNSNGEVTGRLNVGPKMVEFHGQQFQINSKDGKPLFTVDENEVVIGTDKLRVTGPEGALFEHSVETPLVKAEAFKQLRLESPTRSLSMDAPRGINIKAQAGNIEALSQMDIKLHSSDGVLLLDAETVRLPKLPEGTRGGPGVSQGLYEICVCPDGKLYLSVAGLGSTCQEYSRVCQ", "length": 355, "header": "tr|A0A8V0XXF1-1|A0A1D5PL96_CHICK Computationally mapped isoform of Gamma-sarcoglycan OS=Gallus gallus OX=9031 GN=SGCG PE=1 SV=1 CANONICAL=A0A1D5PL96-1" }, "locus": { "chromosome": "1", "start_pos": 177591396, "end_pos": 177531898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014806.1", "url": "https://www.ensembl.org/id/ENSGALT00010014806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008722.1", "url": "https://www.ensembl.org/id/ENSGALP00010008722.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418945", "resource": "KEGG Pathway" }, { "id": "R-GGA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480ZTL0-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "SGCG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVREQYTTATEGTQVERPENQAVYKIGIYGWRKRCLYLFVLLLLILLLVNLALTIWILRVMWFSPAGMGHLQVKQEGLRLEGDSEFLFPLYAKEIRSRVDSPLLLQSPQNVTLSARTVEGEVTGRLTAGPQMVEIQSQHFHINSRDGRPLFTVDEREAVVGADKLRVTGPEGALFEHSVETPLVRPDPFQDLRLESPTRSLSMDAPNGVRVRAPAGSGAALSQMDIVLHSSAGPLVLDAETVCLPRVAQGTRGPGSSQGLYEVCACADGRLYLAAAAAGTTCHENSGVCL", "length": 290 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MCH6-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "Sgcg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVREQYTTVTEGTHIERPENQHVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPIGMGHLHVTQDGLRLEGESEFLFPLYVKEIRSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPQMVEVQSQHFQIRSEDGKPLFTTDEQGVTVSTGRLRVTGPEGAIFEHSVETPLVRADPFEDLRLESPTRSLSMDAPRGVHIKAHTGKMEALSQMDVILQSSDGVLVLDAETVGLPKLEQGTPGPSGSSEGFYEICVCPDGKLYLSAADEATTCEEHSHICL", "length": 291 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1Q504-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "sgcg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVREQYVTTTEESGVLSPVSEYIYMIGIYGWRKRCLYLFVLLLLIILVVNFALTIWILRVMWFNAEGMGYLQVHEDGLRLEGESDFLFPVYAQEIDSREDSALLIQSSENVTLNARNANGDVTGSVSVGPSQAEGFSKYFNISSNHDENLFYADGSGAIVGKGKLRVTGPEGALFEHSVRTPMVKAVLNKELKLESPTRSLSMDAPKGVHVKALAGNVDVTAHFDILLHSAEGLLILDAETVRLPKLPVGEAGTSGDSQGMYNMYEVCVCPSGKLFFSTAGVSSTCSESQDC", "length": 292 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P82348-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "Sgcg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVREQYTTVTEGTHIERPENQHIYKIGIYGWRKRCLYLFVLLLLAILVVNLALTIWILKVMWFSPIGMGHLHVTADGLRLEGESEFLFPLYAKEIRSRVDSSLLLQSTQNVTVSARNSEGEVTGRVKVGAQMVEVQSQHFQINSEDGKPLFSAEEQDVVVGTGRLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHVKANAGKLEALSQMDIILQSSEGVLVLDAETVGLTKLKQGTQGPAGSSNGFYEICACPDGKLYLSMAGEVTTCEEHSHVCL", "length": 291 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0VCU7-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "SGCG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVREQYTTITEGTHIERPENQAVYKIGIYGWRKRCLYLFVLLLLIVLLVNFALTIWILRVMWFSPVGMGHLHVTADGLHLEGESEFLFPLYVKEIRSRVDSSLLLQSTQNVTMNARNTEGEVTGRLKVGPQMVEVQSQQFQIHSKDGKPLFTVDEEKVMVGTDKLRVTGPEGALFEHSVETPLVRPDPPQDLRLESPTRSLSMDAPKGIHIQAPAGKIEALTQMDIVLQSSDGTVVLDAETVCLPELALGSQGPAGSSQGLYEVCVCPDGKLYLSVAGMGTTCHEHSHLCL", "length": 291 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q13326-1", "protein_name": "Gamma-sarcoglycan", "gene_name": "SGCG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVREQYTTATEGICIERPENQYVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPAGMGHLCVTKDGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPKMVEVQNQQFQINSNDGKPLFTVDEKEVVVGTDKLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHNHICL", "length": 291 }, "evidence": [ { "id": "A0A1D5PL96", "url": "https://omabrowser.org/oma/group/A0A1D5PL96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PS75-1", "uniprot_ac": "A0A1D5PS75", "uniprot_id": "A0A1D5PS75_CHICK", "mass": { "chemical_mass": 60470.0, "monoisotopic_mass": 60470.0 }, "refseq": { "ac": "XP_004938456", "name": "male-specific lethal 3 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938456" }, "gene_names": [ { "name": "MSL3", "type": "recommended", "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ] }, { "name": "MSL3", "type": "synonym", "evidence": [ { "id": "XP_004938456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938456" } ] } ], "protein_names": [ { "name": "MSL complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal 3 homolog", "type": "synonym", "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal-3 homolog 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal-3 protein-like 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75/entry#names_and_taxonomy" } ] }, { "name": "male-specific lethal 3 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938456" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938456" } ] }, { "annotation": "Non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction. The MSL complex is required for chromosome stability and genome integrity by maintaining homeostatic levels of H4K16ac. The MSL complex is also involved in gene dosage by promoting up-regulation of genes expressed by the X chromosome. X up-regulation is required to compensate for autosomal biallelic expression. The MSL complex also participates in gene dosage compensation by promoting expression of Tsix non-coding RNA. Acts as a histone reader that specifically recognizes and binds histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex. May play a role X inactivation in females.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P177", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P177#function" }, { "database": "UniProtKB", "id": "ARBA00059382", "url": "https://www.uniprot.org/uniprotkb/ARBA00059382#function" }, { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75#function" }, { "database": "UniProtKB", "id": "A0A8V0XDN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDN7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSL3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75", "locus": {} } ], "crossref": [ { "id": "A0A1D5PS75", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041433", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041433", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418641", "url": "https://www.ncbi.nlm.nih.gov/gene/418641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418641", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTEYAHL", "url": "https://omabrowser.org/oma/group/DTEYAHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P177", "url": "https://www.orthodb.org/?gene=A0A1D5P177", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PS75", "url": "https://www.orthodb.org/?gene=A0A1D5PS75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7V1", "url": "https://www.orthodb.org/?gene=A0A8V0X7V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XDN7", "url": "https://www.orthodb.org/?gene=A0A8V0XDN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3214847", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214847", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P177", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P177", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P177-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P177-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSRGMKFKFHRGERVLCFEPDPTKAKVLYDAKIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARMRRKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRFLAEYHDDFFPESAYVAACEAYYSTKNPRAIY", "length": 522, "header": "tr|A0A1D5PS75-1|A0A1D5PS75_CHICK Isoform 1 of MSL complex subunit 3 OS=Gallus gallus OX=9031 GN=MSL3 PE=4 SV=1 CANONICAL=A0A1D5PS75-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P177-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P177/entry", "sequence": { "sequence": "MTSRGMKFKFHRGERVLCFEPDPTKAKVLYDAKIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARMRRKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRPYLCLKCPHPVIWIS", "length": 505, "header": "tr|A0A1D5P177-1|A0A1D5PS75_CHICK Computationally mapped isoform of MSL complex subunit 3 OS=Gallus gallus OX=9031 GN=MSL3 PE=4 SV=1 CANONICAL=A0A1D5PS75-1" }, "locus": { "chromosome": "1", "start_pos": 124149181, "end_pos": 124136321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004454.1", "url": "https://www.ensembl.org/id/ENSGALT00010004454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002708.1", "url": "https://www.ensembl.org/id/ENSGALP00010002708.1" } ] } }, { "isoform_ac": "A0A1D5PS75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75/entry", "sequence": { "sequence": "MTSRGMKFKFHRGERVLCFEPDPTKAKVLYDAKIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARMRRKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRFLAEYHDDFFPESAYVAACEAYYSTKNPRAIY", "length": 522, "header": "tr|A0A1D5PS75-1|A0A1D5PS75_CHICK Isoform 1 of MSL complex subunit 3 OS=Gallus gallus OX=9031 GN=MSL3 PE=4 SV=1 CANONICAL=A0A1D5PS75-1" }, "locus": { "chromosome": "1", "start_pos": 124149181, "end_pos": 124127620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004457.1", "url": "https://www.ensembl.org/id/ENSGALT00010004457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002710.1", "url": "https://www.ensembl.org/id/ENSGALP00010002710.1" } ] } }, { "isoform_ac": "A0A8V0X7V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7V1/entry", "sequence": { "sequence": "MCFCQWLWIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARMRRKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRFLAEYHDDFFPESAYVAACEAYYSTKNPRAIY", "length": 497, "header": "tr|A0A8V0X7V1-1|A0A1D5PS75_CHICK Computationally mapped isoform of MSL complex subunit 3 OS=Gallus gallus OX=9031 GN=MSL3 PE=4 SV=1 CANONICAL=A0A1D5PS75-1" }, "locus": { "chromosome": "1", "start_pos": 124174606, "end_pos": 124127620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004462.1", "url": "https://www.ensembl.org/id/ENSGALT00010004462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002713.1", "url": "https://www.ensembl.org/id/ENSGALP00010002713.1" } ] } }, { "isoform_ac": "A0A8V0XDN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDN7/entry", "sequence": { "sequence": "MTSRGMKFKFHRGERVLCFEPDPTKAKVLYDAKIVDIIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARIKGRKKRRCRLPGVDSVLKSLPAEENDHNSEKTVSSSSDDSDEGTDEEIKSEESDIEERTEMKEDQDTHSKREMEERAINIEIPEVLKKKLEEDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERSRHHQVTPHANMNLHYVPPEKNVELCKEMVDGLRITFDFTLPLILLYPYEQAQFKKVTSSKFFLPIKENSTNTNRNQEELSPSPPLLNPPTPQSTDSQPATAEPATPKRRKAEPEILQSLRRSTRHTSNCDRLSESSASPQPKRRHLETPTSMPKLFLHLEKKTPVHSGSSSPITLTPSKEGSAVFTGFEGRRNNELNEVLSWKLMPENYPPSDQPPPPSYIYGSQHLLRMFVKLPEILGKMCFPDKNLKALVKHFEMFLRFLAEYHDDFFPESAYVAACEAYYSTKNPRAIY", "length": 520, "header": "tr|A0A8V0XDN7-1|A0A1D5PS75_CHICK Computationally mapped isoform of MSL complex subunit 3 OS=Gallus gallus OX=9031 GN=MSL3 PE=4 SV=1 CANONICAL=A0A1D5PS75-1" }, "locus": { "chromosome": "1", "start_pos": 124149181, "end_pos": 124127620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004460.1", "url": "https://www.ensembl.org/id/ENSGALT00010004460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002712.1", "url": "https://www.ensembl.org/id/ENSGALP00010002712.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418641", "resource": "KEGG Pathway" }, { "id": "R-GGA-3214847", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214847", "resource": "Reactome", "description": "HATs acetylate histones" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A9H7-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSASKGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNSSSWDRWAAEDHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLPGVDSVLKSVPVKEKTKNDENSISSTCHESCGEKNGGIKEHRQRRIKVKTKGKKKVLSLRSRKDMDERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSTSMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 526 }, "evidence": [ { "id": "A0A1D5PS75", "url": "https://omabrowser.org/oma/group/A0A1D5PS75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BFW0-1", "protein_name": "MSL complex subunit 3", "gene_name": "MSL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLAKKAVARLRSTGRKRKRCRLPGVDSVLKSLPADEKDENDENSISSSSDSEEKDGEISEEGDTEEKTEVKEGPELHTKKEMEERTITIEIPDVLKKKLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVIPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQVQYKKVTSSKFFLPIKESTTSTNRNQEELSPSPPLLNPSTPQSTESQPTSGEPTTPKRRKGEPEAFQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPVPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDSYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 520 }, "evidence": [ { "id": "A0A1D5PS75", "url": "https://omabrowser.org/oma/group/A0A1D5PS75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HH51-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSASEGMKFQFHSGEKVLCFEPDATKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNSSWDRWASEDHVLHDTDENRRLQRKLAKKAIARLRGAGGKKRRCRLPGVDSVLKSVPVKETTQNDENSISSTCHDSSGEKNEEIKEHRQRRIKVKTKAKKKVLSLRSRKDMDERTITIDIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKCFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPLSGEPATPKRRKADPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSFIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 525 }, "evidence": [ { "id": "A0A1D5PS75", "url": "https://omabrowser.org/oma/group/A0A1D5PS75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8N5Y2-1", "protein_name": "MSL complex subunit 3", "gene_name": "MSL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 521 }, "evidence": [ { "id": "A0A1D5PS75", "url": "https://omabrowser.org/oma/group/A0A1D5PS75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVG9-1", "protein_name": "MSL complex subunit 3", "gene_name": "Msl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASEGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNRSWDRWAAEEHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLPGVDSVLKSVPVKEKSKNDENSVSSTCHESCGEKNGGIKEHRQRRIKVKAKAKKKVLSLRSRKEMDERTITIDIPDVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHAMMHTHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRPNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY", "length": 525 }, "evidence": [ { "id": "A0A1D5PS75", "url": "https://omabrowser.org/oma/group/A0A1D5PS75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PS75-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PS75-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS75" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS75" }, { "id": "SM00298", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00298" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 89, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P4K7-1", "uniprot_ac": "A0A1D5P4K7", "uniprot_id": "A0A1D5P4K7_CHICK", "mass": { "chemical_mass": 73137.0, "monoisotopic_mass": 73137.0 }, "refseq": {}, "gene_names": [ { "name": "NOL4L", "type": "recommended", "evidence": [ { "id": "A0A1D5P4K7", "database": "UniProtKB", "url": 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"id": "A0A1D5P4K7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P4K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041732", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041732", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR039788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EFRDWCL", "url": "https://omabrowser.org/oma/group/EFRDWCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P4K7", "url": "https://www.orthodb.org/?gene=A0A1D5P4K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYF6", "url": "https://www.orthodb.org/?gene=A0A1D5PYF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM30", "url": "https://www.orthodb.org/?gene=A0A8V0YM30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P4K7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P4K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYF6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKPPLLLRGSRPGDSELGRQFRDWCLRTYGDSAKTKTVTRSKYQRIAEVLQGGSGSGSGSGGGEKGKFQFWVRSKGFRLGNGTREATKMGQVVVYVPVKTGTGADGLSEPEGISLKRVAVVEDFFDIIYSMHVESSTEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFNSNGLEPKESEPPSSLVSGIIDYNMPLTSTYLKQMKLRVMNSQEQDETSVSSEDFDMNDSTWISADQHLNSSLSPSQDESMRSPQNLHGQEDDDSSSESCSGNGSSTLNPSTSSSTQGDSAFPEMNGNGTAAPMDFTASTDDQPINLCDKLTPAHVTPSYQSDSCSTDGLRSRVKYAVKTTAESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADEDDDDHDDHEDNDKINDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQTSQDEPIALDKQHSRDSTAITHSSYSLPASSYSQDPVYINGSLNYSYRGYGSLGGSLQPPAPLQTGNHSNGPTDLSMKGGASSTAQSNSTSRGMQAAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 667, "header": "tr|A0A1D5P4K7-1|A0A1D5P4K7_CHICK Isoform 1 of Nucleolar protein 4 like OS=Gallus gallus OX=9031 GN=NOL4L PE=4 SV=2 CANONICAL=A0A1D5P4K7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P4K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4K7/entry", "sequence": { "sequence": "MPKPPLLLRGSRPGDSELGRQFRDWCLRTYGDSAKTKTVTRSKYQRIAEVLQGGSGSGSGSGGGEKGKFQFWVRSKGFRLGNGTREATKMGQVVVYVPVKTGTGADGLSEPEGISLKRVAVVEDFFDIIYSMHVESSTEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFNSNGLEPKESEPPSSLVSGIIDYNMPLTSTYLKQMKLRVMNSQEQDETSVSSEDFDMNDSTWISADQHLNSSLSPSQDESMRSPQNLHGQEDDDSSSESCSGNGSSTLNPSTSSSTQGDSAFPEMNGNGTAAPMDFTASTDDQPINLCDKLTPAHVTPSYQSDSCSTDGLRSRVKYAVKTTAESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADEDDDDHDDHEDNDKINDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQTSQDEPIALDKQHSRDSTAITHSSYSLPASSYSQDPVYINGSLNYSYRGYGSLGGSLQPPAPLQTGNHSNGPTDLSMKGGASSTAQSNSTSRGMQAAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 667, "header": "tr|A0A1D5P4K7-1|A0A1D5P4K7_CHICK Isoform 1 of Nucleolar protein 4 like OS=Gallus gallus OX=9031 GN=NOL4L PE=4 SV=2 CANONICAL=A0A1D5P4K7-1" }, "locus": { "chromosome": "20", "start_pos": 10567287, "end_pos": 10521329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032181.1", "url": "https://www.ensembl.org/id/ENSGALT00010032181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018971.1", "url": "https://www.ensembl.org/id/ENSGALP00010018971.1" } ] } }, { "isoform_ac": "A0A1D5PYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYF6/entry", "sequence": { "sequence": "MGPGCRLGRSPCGAGDGRKEAGSGCRAPGWRHRVGTATSLCATRDVGLGPVRRQALDETSVSSEDFDMNDSTWISADQHLNSSLSPSQDESMRSPQNLHGQEDDDSSSESCSGNGSSTLNPSTSSSTQGDSAFPEMNGNGTAAPMDFTASTDDQPINLCDKLTPAHVTPSYQSDSCSTDGLRSRVKYAVKTTAESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADEDDDDHDDHEDNDKINDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQTSQDEPIALDKQHSRDSTAITHSSYSLPASSYSQDPVYINGSLNYSYRGYGSLGGSLQPPAPLQTGNHSNGPTDLSMKGGASSTAQSNSTSRGMQAAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 494, "header": "tr|A0A1D5PYF6-1|A0A1D5PYF6_CHICK Computationally mapped isoform of Nucleolar protein 4 like OS=Gallus gallus OX=9031 GN=NOL4L PE=4 SV=2 CANONICAL=A0A1D5P4K7-1" }, "locus": { "chromosome": "20", "start_pos": 10535162, "end_pos": 10521329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032178.1", "url": "https://www.ensembl.org/id/ENSGALT00010032178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018968.1", "url": "https://www.ensembl.org/id/ENSGALP00010018968.1" } ] } }, { "isoform_ac": "A0A8V0YM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM30/entry", "sequence": { "sequence": "MKFQRGARPGPPHLPRHSPCRLQIGATPRLRTASQQKAGMPGGDGWIYFQGAISVFPQPVCGTCPELGPAAPCRASHWLQGGAVSAPPKSSSAGDGGADGLSEPEGISLKRVAVVEDFFDIIYSMHVESSTEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFNSNGLEPKESEPPSSLVSGIIDYNMPLTSTYLKQMKLRVMNSQEQDETSVSSEDFDMNDSTWISADQHLNSSLSPSQDESMRSPQNLHGQEDDDSSSESCSGNGSSTLNPSTSSSTQGDSAFPEMNGNGTAAPMDFTASTDDQPINLCDKLTPAHVTPSYQSDSCSTDGLRSRVKYAVKTTAESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADEDDDDHDDHEDNDKINDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQTSQDEPIALDKQHSRDSTAITHSSYSLPASSYSQDPVYINGSLNYSYRGYGSLGGSLQPPAPLQTGNHSNGPTDLSMKGGASSTAQSNSTSRGMQAAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 660, "header": "tr|A0A8V0YM30-1|A0A1D5P4K7_CHICK Computationally mapped isoform of Nucleolar protein 4 like OS=Gallus gallus OX=9031 GN=NOL4L PE=4 SV=1 CANONICAL=A0A1D5P4K7-1" }, "locus": { "chromosome": "20", "start_pos": 10565186, "end_pos": 10521329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032184.1", "url": "https://www.ensembl.org/id/ENSGALT00010032184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018974.1", "url": "https://www.ensembl.org/id/ENSGALP00010018974.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LMK3-1", "protein_name": "Nucleolar protein 4-like", "gene_name": "Nol4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKPTLLLRGGWERERSPGDSELGRQFRDWCLRTYGDSAKTKTVTRSKYQRIAEVLQGGGGTGAGSGPAAGEKGKFQFWVRSKGFRLGSGREPKMGQVVYVPVKTGSGADGLSEPEGISLKRVAVVEDFFDIIYSMHVESSAEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFNSSGPEPKENEPPSPLVSGIIDYNMPLTSTYLKQMKLRVMNSQEQDETSVSSEDFDMNDSTWMSADPHLASSLSPNQEERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGAAAPMDFTASAEDQPINLCEKLPPGTALGTPSYPSDGCGTDGLRSRVKYGVKSTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPAADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQEEPIALDKQHPRDSTAITHSTYSLPASAYSQDPVYVNGGLNYSYRGYGSLSSNLQPSASLQTGSHSNGPTDLSMKGGASTPTPPTPTPSSNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 679 }, "evidence": [ { "id": "A0A1D5P4K7", "url": "https://omabrowser.org/oma/group/A0A1D5P4K7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MY1-1", "protein_name": "Nucleolar protein 4-like", "gene_name": "NOL4L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGAVAPMDFTTAAEDQPINLCDKLPPATALGTASYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPIALDKQHSRDSAAITHSTYSLPASSYSQDPVYANGGLNYSYRGYGALSSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTTPTPTPSSTSTSRPVPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 436 }, "evidence": [ { "id": "A0A1D5P4K7", "url": "https://omabrowser.org/oma/group/A0A1D5P4K7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4K7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P4K7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 667, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P4K7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P4K7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P4K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4K7" }, { "id": "PF23079", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 4 helical", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 517, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 341 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P4W6-1", "uniprot_ac": "A0A1D5P4W6", "uniprot_id": "A0A1D5P4W6_CHICK", "mass": { "chemical_mass": 65905.0, "monoisotopic_mass": 65905.0 }, "refseq": { "ac": "XP_015132595", "name": "kelch-like protein 30 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132595" }, "gene_names": [ { "name": "KLHL30", "type": "recommended", "evidence": [ { "id": "A0A1D5P4W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ] }, { "name": "KLHL30", "type": "synonym", "evidence": [ { "id": "XP_015132595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132595" } ] } ], "protein_names": [ { "name": "Kelch like family member 30", "type": "synonym", "evidence": [ { "id": "A0A1D5P4W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 30 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015132595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132595" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132595" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6", "locus": { "chromosome": "9", "start_pos": 4489181, "end_pos": 4485525, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024935", "url": "https://www.ensembl.org/id/ENSGALG00010024935" } ] } } ], "crossref": [ { "id": "A0A1D5P4W6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P4W6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006260", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006260", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18469", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18469", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424851", "url": "https://www.ncbi.nlm.nih.gov/gene/424851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424851", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424851", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFYSGVC", "url": "https://omabrowser.org/oma/group/WFYSGVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P4W6", "url": "https://www.orthodb.org/?gene=A0A1D5P4W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5D1", "url": "https://www.orthodb.org/?gene=A0A8V1A5D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132595", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLNVDDFDFCLPSHAQGVLEGLQRLRAHPKLSDVTLLAGGREFPCHRGVLALCSHYFHAMFSGDFAESIAARVELKEVDPGALETLLDFAYTGKVTVNQGNVEGLMRTSSQLHFPTIQQVCSRYLRQQMDATNCLGICEFGESHGCPEVSSKAWSFLQENFEAVSQQEEFLQLSKERLAVYLSNEQLQVQEEQSVAEAVLRWVRYDPGQRAQFLPELLELARLVSLPDHYLQNLLAAEPLVRDSAASQALVARSRATLGATGTVPTPPNAAPPQKLEEVLVVVGGRVLEESEDEEGGLETPAAPRNFAFYNPKTRRWMALPDFPDYNKWGFSLVALNNDVYVTGGSRGSRNDTWSTTQAWRFCPKDGAWTAIASMLRARTNHTSAVLNGEIYVLGGTTVEVVEVERYDPYNQSWAAISPALKYVSNFAAAGCLGKLYLVGSCAVKYNALTLQCYNPVRDAWSVITSPFIPKYLSAPRCATLHGLIYLIGDNTKKVHVYDPEANIWQKVQLLHTLHENGGMVPLGDRLFVTGGHWKGMDGDYRVEMEVYDCAKDRWVREGSLPCLWLFHSSSSIFMDTSKWTEAFPGDQRW", "length": 591, "header": "tr|A0A1D5P4W6-1|A0A1D5P4W6_CHICK Isoform 1 of Kelch like family member 30 OS=Gallus gallus OX=9031 GN=KLHL30 PE=4 SV=2 CANONICAL=A0A1D5P4W6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6/entry", "sequence": { "sequence": "MVLNVDDFDFCLPSHAQGVLEGLQRLRAHPKLSDVTLLAGGREFPCHRGVLALCSHYFHAMFSGDFAESIAARVELKEVDPGALETLLDFAYTGKVTVNQGNVEGLMRTSSQLHFPTIQQVCSRYLRQQMDATNCLGICEFGESHGCPEVSSKAWSFLQENFEAVSQQEEFLQLSKERLAVYLSNEQLQVQEEQSVAEAVLRWVRYDPGQRAQFLPELLELARLVSLPDHYLQNLLAAEPLVRDSAASQALVARSRATLGATGTVPTPPNAAPPQKLEEVLVVVGGRVLEESEDEEGGLETPAAPRNFAFYNPKTRRWMALPDFPDYNKWGFSLVALNNDVYVTGGSRGSRNDTWSTTQAWRFCPKDGAWTAIASMLRARTNHTSAVLNGEIYVLGGTTVEVVEVERYDPYNQSWAAISPALKYVSNFAAAGCLGKLYLVGSCAVKYNALTLQCYNPVRDAWSVITSPFIPKYLSAPRCATLHGLIYLIGDNTKKVHVYDPEANIWQKVQLLHTLHENGGMVPLGDRLFVTGGHWKGMDGDYRVEMEVYDCAKDRWVREGSLPCLWLFHSSSSIFMDTSKWTEAFPGDQRW", "length": 591, "header": "tr|A0A1D5P4W6-1|A0A1D5P4W6_CHICK Isoform 1 of Kelch like family member 30 OS=Gallus gallus OX=9031 GN=KLHL30 PE=4 SV=2 CANONICAL=A0A1D5P4W6-1" }, "locus": { "chromosome": "9", "start_pos": 4488623, "end_pos": 4486070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060898.1", "url": "https://www.ensembl.org/id/ENSGALT00010060898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037655.1", "url": "https://www.ensembl.org/id/ENSGALP00010037655.1" } ] } }, { "isoform_ac": "A0A8V1A5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D1/entry", "sequence": { "sequence": "MVLNVDDFDFCLPSHAQGVLEGLQRLRAHPKLSDVTLLAGGREFPCHRGVLALCSHYFHAMFSGDFAESIAARVELKEVDPGALETLLDFAYTGKVCSRYLRQQMDATNCLGICEFGESHGCPEVSSKAWSFLQENFEAVSQQEEFLQLSKERLAVYLSNEQLQVQEEQSVAEAVLRWVRYDPGQRAQFLPELLELARLVSLPDHYLQNLLAAEPLVRDSAASQALVARSRATLGATGTVPTPPNAAPPQKLEEVLVVVGGRVLEESEDEEGGLETPAAPRNFAFYNPKTRRWMALPDFPDYNKWGFSLVALNNDVYVTGGSRGSRNDTWSTTQAWRFCPKDGAWTAIASMLRARTNHTSAVLNGEIYVLGGTTVEVVEVERYDPYNQSWAAISPALKYVSNFAAAGCLGKLYLVGSCAVKYNALTLQCYNPVRDAWSVITSPFIPKYLSAPRCATLHGLIYLIGDNTKKVHVYDPEANIWQKVQLLHTLHENGGMVPLGDRLFVTGGHWKGMDGDYRVEMEVYDCAKDRWVREGSLPCLWLFHSSSSIFMDTSKWTEAFPGDQRW", "length": 566, "header": "tr|A0A8V1A5D1-1|A0A1D5P4W6_CHICK Computationally mapped isoform of Kelch like family member 30 OS=Gallus gallus OX=9031 GN=KLHL30 PE=4 SV=1 CANONICAL=A0A1D5P4W6-1" }, "locus": { "chromosome": "9", "start_pos": 4488623, "end_pos": 4486070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060894.1", "url": "https://www.ensembl.org/id/ENSGALT00010060894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037651.1", "url": "https://www.ensembl.org/id/ENSGALP00010037651.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424851", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N2Y0-1", "protein_name": "Kelch-like protein 30 isoform X2", "gene_name": "Klhl30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRNLDSLDFHLPSHAQDMLDGLQRLRSLPKLADVTLLVGDQELPCHRSLLALSSPYFHAMFAGDFAESFSARVELRDVEPAAAGQLVDFVYTGRLTITQTNVEALTRTASRLHFPTVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAQEDEFLQLPRDRLATCLASDLLQVQPEQSRLQALLRWVRHDPQERSAHLPELLSLVHLDAVPRPCVQQLLATEPLIQESEACQEALSQGHRRELPGLPQKMQEVLVVVGGRALEEDEEGGEEPSAHTGNFAFYNTKARQWMALPDFPDYHKWGFSLAALNSDVYVTGGSRGTKTDTWSTTQAWCFPLKEAVWKPVAPMLKARTNHASTALNGEIYAIGGTALDAVEVERYDPYTDSWTPVSPALKYVSNFSAASCQGRLYLVGSSACKYNMLALQCYSPVTDVWSVIASPFLPKYLSSPRCAALNGALYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVSLGDALYVTGGRWQGMDGDYHVEMEAYDTVRDAWARHGSLPRLWLYHGASTIFLDISKWTKPFSPSATQEH", "length": 581 }, "evidence": [ { "id": "A0A1D5P4W6", "url": "https://omabrowser.org/oma/group/A0A1D5P4W6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZHA2-1", "protein_name": "Kelch-like family member 30", "gene_name": "Klhl30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRNVDDLDFHLPSHAQDMLEGLQRLRSLPKLADVTLLVGDQELPCHRSLLALNSPYFHAMFAGDFAESFSARVELRDVEPAAVGQLVDFVYTGRLTITQSNVEALTRSASRLHFPTVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAQEDEFLQLPRDRLATCLASDLLQVQPEQSRLEALLRWVRHDPQDRAAYLPELLNLVHLDALPRPCVQQLLATEPLIQESEACQEALSQGHSAEPPGLPQKMQEVLVVVGGRALEEDEEGGEEPSPHTGNFAFYNTKARQWMALPDFPDYHKWGFSLATLNSDVYVTGGSRGTKTDTWSTTQAWCFPLKEAVWKPVAPMLKARTNHASTALNGEIYAIGGTALDAVEVERYDPYTDSWAPVRPALKYVSNFSAASCQGRLYLVGSSACKYNMLALQCYSPVTDVWSVIASPFLPKYLSSPRCAALNGALYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDLLYVTGGRWQGMDGDYHVEMEAYDTVRDAWARHGSLPRLWLYHGASTIFLDISKWTQPFSPTAPREH", "length": 581 }, "evidence": [ { "id": "A0A1D5P4W6", "url": "https://omabrowser.org/oma/group/A0A1D5P4W6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LTF2-1", "protein_name": "Kelch like family member 30", "gene_name": "KLHL30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRNVDDLDFHLPSHAQDMLDGLQRLRFQPKLADVTLLVGGRELPCHRGLLALSSPYFHAMFAGDFAESFSARVELRDVEPAVVAQLVDFVYTGRLTITQANVEALTRTAARLHFPAVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAREDEFLQLSQERLATCLASDLLQVQPEQSRLEALLRWVRHDSQARAAHLPELLGLVHLDAVPRPHVQQLLATEPLIRESEACREALSQGHEAALLALPQKLEEVLVVVGGRALEEEEGAEELAPQPGNFAFYDTKAQRWMALPDFPDYHKWGFSLAALNNDVYVTGGSRGTKTDTWSTTQAWCFPLKEAAWRPVAPMRKARTNHASAALNGEIYAIGGTTLDVVEVESYDPYTDTWTPVSPALKYVSNFSAAGCGGRLYLVGSSACKYNALALQCYNPVADAWSVIASPFLPKYLSSPRCAALQGALYLVGDNTKKVYVYDPGANLWQKVQALHSLHENGALVPLGDALYVTGGRWQGMDGDYHVEMEAYDPGRDAWIRHGALPRLWLYHGASAVFLDVSKWTQPFGPAQEP", "length": 578 }, "evidence": [ { "id": "A0A1D5P4W6", "url": "https://omabrowser.org/oma/group/A0A1D5P4W6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0D2K2-1", "protein_name": "Kelch-like protein 30", "gene_name": "KLHL30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRNVDDLDFHLPSHAQDMLDGLQRLRSQPKLADVTLLVGGRELPCHRGLLALSSPYFHAMFAGDFAESFSARVELRDVEPAVVGQLVDFVYTGRLTITQGNVEALTRTAARLHFPSVQKVCGRYLQQQLDAANCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAREDEFLQLPRERLVTCLAGDLLQVQPEQSRLEALMRWVRHDPQARAAHLPELLSLVHLDAVPRPCVQQLLASEPLIQESEACRAALSQGHDGAPLALQQKLEEVLVVVGGQALEEEEAGEEPTPGLGNFAFYNSKAKRWMALPDFPDYHKWGFSLAALNNNIYVTGGSRGTKTDTWSTTQAWCFPLKEASWKPVAPMLKPRTNHASAALNGEIYVIGGTTLDVVEVESYDPYTDSWTPVSPALKYVSNFSAAGCRGRLYLVGSSACKYNALALQCYNPVTDAWSVIASPFLPKYLSSPRCAALHGELYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDALYVTGGRWQGMEGDYHVEMEAYDTVRDTWTRHGALPRLWLYHGASTVFLDVSKWTQPSGPTQEH", "length": 578 }, "evidence": [ { "id": "A0A1D5P4W6", "url": "https://omabrowser.org/oma/group/A0A1D5P4W6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C3F7-1", "protein_name": "Kelch-like protein 30", "gene_name": "Klhl30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRNLDDLDFHLPSHAQDMLEGLQRLRSLPKLADVTLLVGDQELPCHRSLLALNSPYFHAMFAGDFTESFLARVELRDVEPAMVGQLVDFVYTGRLTITQANVEALTRSASRLNFPTVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAQEDEFLQLARDRLATCLASDLLQVQPEQSRLEALLRWVRHDPQDRAAHLPELLSLVHLDAVPRPCVQQLLATEPLIQESEACQEALSQGHSEELPGLPQKMQEVLVVVGGRALEEDEDGGEEPSHHTGNFAFYNTKARQWMALPDFPDYHKWGFSLAALNSDVYVTGGSRGTKTDTWSTTQAWCFPLKEAIWKPVAPMLKARTNHASTALNGEIYAIGGTALDAVEVERYDPYTDSWAPVGPAPKYVSNFSAAGCQGRLYLVGSSACKYNMLALQCYSPVTDAWSVIASPFLPKYLSSPRCAALNGALYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDLLYVTGGRWQGMDGDYHVEMEAYDTVRDAWARHGSLPRLWLYHGASTIFLDVSKWTQPFIPTAPQEH", "length": 581 }, "evidence": [ { "id": "A0A1D5P4W6", "url": "https://omabrowser.org/oma/group/A0A1D5P4W6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P4W6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P4W6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P4W6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P4W6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P4W6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 267 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 352, "end_pos": 354 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 412, "end_pos": 414 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"uniprot_ac": "A0A1D5P533", "uniprot_id": "A0A1D5P533_CHICK", "mass": { "chemical_mass": 80047.0, "monoisotopic_mass": 80047.0 }, "refseq": { "ac": "XP_004949239", "name": "ras and EF-hand domain-containing protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949239" }, "gene_names": [ { "name": "RASEF", "type": "recommended", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "name": "RASEF", "type": "synonym", "evidence": [ { "id": "XP_004949239", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949239" } ] } ], "protein_names": [ { "name": "Ras and EF-hand domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533/entry#names_and_taxonomy" } ] }, { "name": "Ras-related protein Rab-45", "type": "synonym", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533/entry#names_and_taxonomy" } ] }, { "name": "ras and EF-hand domain-containing protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004949239", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949239" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004949239.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949239" } ] }, { "annotation": "Rab GTPase that acts as a dynein adapter protein, thereby activating dynein-mediated transport and dynein-dynactin motility on microtubules. RASEF-mediated dynein motility is Ca(2+)-independent. Also regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533#function" }, { "database": "UniProtKB", "id": "ARBA00094439", "url": "https://www.uniprot.org/uniprotkb/ARBA00094439#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASEF", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533", "locus": { "chromosome": "Z", "start_pos": 40322681, "end_pos": 40362482, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015541", "url": "https://www.ensembl.org/id/ENSGALG00010015541" } ] } } ], "crossref": [ { "id": "A0A1D5P533", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P533", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012576", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012576", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00154", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00154", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427451", "url": "https://www.ncbi.nlm.nih.gov/gene/427451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P533", "url": "https://www.orthodb.org/?gene=A0A1D5P533", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949239", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P533-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAETAGDDQSRLRALFLACDANGSGRIEREDFEALCAELRVRPAEAEAIFQRLDSDRDGAITFREFARGFRGATRLRSSGGPGEPEPEEEGEEAAATWSTAGLEQPWRDFEVRLGDEARYIPRQEQVSVLYQNIHIVEPRLIQPYEHVIKNFIREIKLQSTEMETLAIAVKRAQDKAAVQLSELEEEMEQRIQAAEQKVKKEEKRKAEEALNELKRQYDTEVGDLQVTIKKLKKVEEQSKNINSREDVIELKKRMHDVLLENQKLKKDLLEAQTNIAFLRSELDSLKSEYADQTLNTERDLEMIREYTEDRDNLERQIEILQSANRKLHDSNDGLRTALENSFSKFNRSLRLANTSPGSTISRSSPKCSGGQSPLNPRYDRSSPSCVDEDYDSLALCDPMQRINCEVDSLPESCFDSGLSTLRDSNEYDSEVEYRHQRIFQRPQCMQENYGGDASDTDVPEIRDEETYSPDNSSTILDWKSSRPVSRSSSVASTRKYISALTPQSDATECTPKYPSSEKAYKIVLAGDAAVGKSSFLMRLCKNEFRGNTSATLGVDFQMKRLIVDGEPTVLQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKSFLNVREWVDMIADATHENIPIMMVGNKADLRQAVTEQGQKCISTNYGEKLAMTYNALFCETSAKDGSNIVEAVLHLAREVRKRSDNRDDTRMVCEGS", "length": 705, "header": "tr|A0A1D5P533-1|A0A1D5P533_CHICK Isoform 1 of Ras and EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=RASEF PE=3 SV=1 CANONICAL=A0A1D5P533-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P533-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533/entry", "sequence": { "sequence": "MDAETAGDDQSRLRALFLACDANGSGRIEREDFEALCAELRVRPAEAEAIFQRLDSDRDGAITFREFARGFRGATRLRSSGGPGEPEPEEEGEEAAATWSTAGLEQPWRDFEVRLGDEARYIPRQEQVSVLYQNIHIVEPRLIQPYEHVIKNFIREIKLQSTEMETLAIAVKRAQDKAAVQLSELEEEMEQRIQAAEQKVKKEEKRKAEEALNELKRQYDTEVGDLQVTIKKLKKVEEQSKNINSREDVIELKKRMHDVLLENQKLKKDLLEAQTNIAFLRSELDSLKSEYADQTLNTERDLEMIREYTEDRDNLERQIEILQSANRKLHDSNDGLRTALENSFSKFNRSLRLANTSPGSTISRSSPKCSGGQSPLNPRYDRSSPSCVDEDYDSLALCDPMQRINCEVDSLPESCFDSGLSTLRDSNEYDSEVEYRHQRIFQRPQCMQENYGGDASDTDVPEIRDEETYSPDNSSTILDWKSSRPVSRSSSVASTRKYISALTPQSDATECTPKYPSSEKAYKIVLAGDAAVGKSSFLMRLCKNEFRGNTSATLGVDFQMKRLIVDGEPTVLQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKSFLNVREWVDMIADATHENIPIMMVGNKADLRQAVTEQGQKCISTNYGEKLAMTYNALFCETSAKDGSNIVEAVLHLAREVRKRSDNRDDTRMVCEGS", "length": 705, "header": "tr|A0A1D5P533-1|A0A1D5P533_CHICK Isoform 1 of Ras and EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=RASEF PE=3 SV=1 CANONICAL=A0A1D5P533-1" }, "locus": { "chromosome": "Z", "start_pos": 40362384, "end_pos": 40323685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037357.1", "url": "https://www.ensembl.org/id/ENSGALT00010037357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021651.1", "url": "https://www.ensembl.org/id/ENSGALP00010021651.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" }, { "name": "endolysosome", "id": "GO:0036019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036019", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P533", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", 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"id": "NP_001280103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280103" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004000.1, HAEK01183017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1, CN228827.1 and CN235623.1. On Jun 3, 2014 this sequence version replaced XP_001233377.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001280103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280103" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P546", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546", "locus": { "chromosome": "15", "start_pos": 4529978, "end_pos": 4527266, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020990", "url": "https://www.ensembl.org/id/ENSGALG00010020990" } ] } } ], "crossref": [ { "id": "A0A1D5P546", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P546", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041277", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041277", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396190", "url": "https://www.ncbi.nlm.nih.gov/gene/396190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396190", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TITLXES", "url": "https://omabrowser.org/oma/group/TITLXES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P546", "url": "https://www.orthodb.org/?gene=A0A1D5P546", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001280103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280103", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P546", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P546-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN", "length": 229, "header": "tr|A0A1D5P546-1|A0A1D5P546_CHICK Isoform 1 of Ubiquitin B OS=Gallus gallus OX=9031 GN=UBB PE=3 SV=1 CANONICAL=A0A1D5P546-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P546-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546/entry", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN", "length": 229, "header": "tr|A0A1D5P546-1|A0A1D5P546_CHICK Isoform 1 of Ubiquitin B OS=Gallus gallus OX=9031 GN=UBB PE=3 SV=1 CANONICAL=A0A1D5P546-1" }, "locus": { "chromosome": "15", "start_pos": 4529241, "end_pos": 4528555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050736.1", "url": "https://www.ensembl.org/id/ENSGALT00010050736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029959.1", "url": "https://www.ensembl.org/id/ENSGALP00010029959.1" } ] } }, { "isoform_ac": "A0A8V0ZMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ2/entry", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN", "length": 153, "header": "tr|A0A8V0ZMQ2-1|A0A8V0ZMQ2_CHICK Computationally mapped isoform of Ubiquitin B OS=Gallus gallus OX=9031 GN=UBB PE=3 SV=1 CANONICAL=A0A1D5P546-1" }, "locus": { "chromosome": "15", "start_pos": 4529241, "end_pos": 4528555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050734.1", "url": "https://www.ensembl.org/id/ENSGALT00010050734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029957.1", "url": "https://www.ensembl.org/id/ENSGALP00010029957.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396190", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P546", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P546", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P546-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 229, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P546-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P546" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P546" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 76, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P5D7-1", "uniprot_ac": "A0A1D5P5D7", "uniprot_id": "A0A1D5P5D7_CHICK", "mass": { "chemical_mass": 11905.0, "monoisotopic_mass": 11905.0 }, "refseq": { "ac": "XP_024999954", "name": "reprimo-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999954" }, "gene_names": [ { "name": "RPRML", "type": "recommended", "evidence": [ { "id": "A0A1D5P5D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7" } ] }, { "name": "RPRML", "type": "synonym", "evidence": [ { "id": "XP_024999954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999954" } ] } ], "protein_names": [ { "name": "Reprimo like", "type": "synonym", "evidence": [ { "id": "A0A1D5P5D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7/entry#names_and_taxonomy" } ] }, { "name": "reprimo-like protein", "type": "synonym", "evidence": [ { "id": "XP_024999954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999954" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5D7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPRML", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7", "locus": {} } ], "crossref": [ { "id": "A0A1D5P5D7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P5D7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042256", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "112529959", "url": "https://www.ncbi.nlm.nih.gov/gene/112529959", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:112529959", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112529959", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSWIHSA", "url": "https://omabrowser.org/oma/group/SSWIHSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P5D7", "url": "https://www.orthodb.org/?gene=A0A1D5P5D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P5D7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGSFFNQSLLEQGAYPNRTRGLGLLLACCNGTSSVLAPDGGSSVLAPDERSLYITRVVQIAVLCVLSLTVVFGIFFLGCNLLIKSESMINFLVKDRRPSKDVGAAIMGLY", "length": 111, "header": "tr|A0A1D5P5D7-1|A0A1D5P5D7_CHICK Isoform 1 of Reprimo like OS=Gallus gallus OX=9031 GN=RPRML PE=4 SV=2 CANONICAL=A0A1D5P5D7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5D7-1", "url": 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The reference sequence was derived from JAENSK010000214.1. On Dec 17, 2020 this sequence version replaced XP_015142461.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376299" } ] }, { "annotation": "Show that the transcription factor PU.1 and its functional partner, IRF4, are involved in the expression of activation induced cytidine deaminase gene in chicken B cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001376299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376299" }, { "database": "PubMed", "id": "20299102", "url": "https://glygen.org/publication/PubMed/20299102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5I9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { 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"title": "Transcription factors PU.1 and IRF4 regulate activation induced cytidine deaminase in chicken B cells.", "journal": "Molecular immunology", "date": "2010-04", "authors": "Luo Hong, Tian Ming", "evidence": [ { "database": "RefSeq", "id": "NP_001376299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376299" } ], "reference": [ { "type": "PubMed", "id": "20299102", "url": "https://glygen.org/publication/PubMed/20299102" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5I9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", 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Pathway" ] }, { "id": "CEKDEWT", "url": "https://omabrowser.org/oma/group/CEKDEWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P5M0", "url": "https://www.orthodb.org/?gene=A0A1D5P5M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9F4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9F4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTQDERQINSEYAVSLLEQLKFFYEQQLLTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAISDSTVEQLYETACFLQVDDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEAAAENPGSLYSSVCYSPQAEKVYKLCNPPADLHKVGTLVTPDNDIYIAGGQVPLKNAKTNHSKSSKLQAAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSTAVAVHNCIYVMAHNLMYCYFPRSDAWVEMAMRQTSRCFASAAAFGDKIFYIGGLHIASNSGIRLPSSTVDGSSVTVEIYDVNKNEWRMAANIPAKRYSDPCVRAVVISNSLCVFIRETHMNERARYATYQYDLELDRWFLRQHISERVLWDLGKDFRCTVGKLYPSCLEESPWKPPTYLFSPDGADEFELDGEMVTLPPV", "length": 623, "header": "tr|A0A1D5P5M0-1|A0A1D5P5M0_CHICK Isoform 1 of Kelch repeat and BTB domain containing 2 OS=Gallus gallus OX=9031 GN=KBTBD2 PE=4 SV=1 CANONICAL=A0A1D5P5M0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0/entry", "sequence": { "sequence": "MSTQDERQINSEYAVSLLEQLKFFYEQQLLTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAISDSTVEQLYETACFLQVDDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEAAAENPGSLYSSVCYSPQAEKVYKLCNPPADLHKVGTLVTPDNDIYIAGGQVPLKNAKTNHSKSSKLQAAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSTAVAVHNCIYVMAHNLMYCYFPRSDAWVEMAMRQTSRCFASAAAFGDKIFYIGGLHIASNSGIRLPSSTVDGSSVTVEIYDVNKNEWRMAANIPAKRYSDPCVRAVVISNSLCVFIRETHMNERARYATYQYDLELDRWFLRQHISERVLWDLGKDFRCTVGKLYPSCLEESPWKPPTYLFSPDGADEFELDGEMVTLPPV", "length": 623, "header": "tr|A0A1D5P5M0-1|A0A1D5P5M0_CHICK Isoform 1 of Kelch repeat and BTB domain containing 2 OS=Gallus gallus OX=9031 GN=KBTBD2 PE=4 SV=1 CANONICAL=A0A1D5P5M0-1" }, "locus": { "chromosome": "2", "start_pos": 47985984, "end_pos": 47981145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046706.1", "url": "https://www.ensembl.org/id/ENSGALT00010046706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027814.1", "url": "https://www.ensembl.org/id/ENSGALP00010027814.1" } ] } }, { "isoform_ac": "A0A8V0Z9F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9F4/entry", "sequence": { "sequence": "MVLVLICMFFFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAISDSTVEQLYETACFLQVDDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEAAAENPGSLYSSVCYSPQAEKVYKLCNPPADLHKVGTLVTPDNDIYIAGGQVPLKNAKTNHSKSSKLQAAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSTAVAVHNCIYVMAHNLMYCYFPRSDAWVEMAMRQTSRCFASAAAFGDKIFYIGGLHIASNSGIRLPSSTVDGSSVTVEIYDVNKNEWRMAANIPAKRYSDPCVRAVVISNSLCVFIRETHMNERARYATYQYDLELDRWFLRQHISERVLWDLGKDFRCTVGKLYPSCLEESPWKPPTYLFSPDGADEFELDGEMVTLPPV", "length": 578, "header": "tr|A0A8V0Z9F4-1|A0A8V0Z9F4_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 2 OS=Gallus gallus OX=9031 GN=KBTBD2 PE=4 SV=1 CANONICAL=A0A1D5P5M0-1" }, "locus": { "chromosome": "2", "start_pos": 47985984, "end_pos": 47983809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046705.1", "url": "https://www.ensembl.org/id/ENSGALT00010046705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027813.1", "url": "https://www.ensembl.org/id/ENSGALP00010027813.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420749", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RZY6-1", "protein_name": "Kelch repeat and BTB domain containing 2", "gene_name": "KBTBD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYKEVRAMFMSGLSESKQTHIHLRNVDSATLQIIITYTYTGNLAISDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEVYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFEMDGEMVALPPV", "length": 572 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZVS6-1", "protein_name": "Kelch repeat and BTB domain containing 2", "gene_name": "Kbtbd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTQEERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAAALQMIITYAYTGNLAINDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYRQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFELDGEMVALPPV", "length": 623 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HMP9-1", "protein_name": "Kelch repeat and BTB domain-containing protein 2", "gene_name": "Kbtbd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTPEERHINPEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAAALQMIITYAYTGNLAVNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVFCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWTLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFELDGEMVALPPV", "length": 623 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3X9X1-1", "protein_name": "Kelch repeat and BTB domain-containing protein 2", "gene_name": "Kbtbd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTQEERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAAALQMIIAYAYTGNLAVNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYRQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFELDGEMVALPPV", "length": 623 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3LBC6-1", "protein_name": "Kelch repeat and BTB domain containing 2", "gene_name": "KBTBD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTQDEKQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAVSDGTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDQWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFELDGEMVALPPV", "length": 623 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IY47-1", "protein_name": "Kelch repeat and BTB domain-containing protein 2", "gene_name": "KBTBD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTQDERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQDAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWVEMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSTDGTEEFELDGEMVALPPV", "length": 623 }, "evidence": [ { "id": "A0A1D5P5M0", "url": "https://omabrowser.org/oma/group/A0A1D5P5M0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cellular response to insulin stimulus", "id": "GO:1900076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P5M0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P5M0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P5M0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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] }, { "name": "V-type immunoglobulin domain-containing suppressor of T-cell activation", "type": "synonym", "evidence": [ { "id": "XP_001231981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231981" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001231981.1. 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"database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769500", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNCTFHT", "url": 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"tr|A0A1D5P5M8-1|A0A1D5P5M8_CHICK Isoform 1 of V-set immunoregulatory receptor OS=Gallus gallus OX=9031 GN=VSIR PE=4 SV=2 CANONICAL=A0A1D5P5M8-1" }, "locus": { "chromosome": "6", "start_pos": 12627365, "end_pos": 12621576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048476.1", "url": "https://www.ensembl.org/id/ENSGALT00010048476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028584.1", "url": "https://www.ensembl.org/id/ENSGALP00010028584.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769500", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L5H3-1", "protein_name": "V-set immunoregulatory receptor", "gene_name": "Vsir", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_429403" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_429403.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_429403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_429403" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P5V6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5V6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBTD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5V6", "locus": { "chromosome": "13", "start_pos": 8415021, "end_pos": 8362631, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012327", "url": "https://www.ensembl.org/id/ENSGALG00010012327" } ] } } ], "crossref": [ { "id": "A0A1D5P5V6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P5V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037395", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037395", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17121", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17121", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416202", "url": "https://www.ncbi.nlm.nih.gov/gene/416202", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416202", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416202", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GTGGECQ", "url": "https://omabrowser.org/oma/group/GTGGECQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P5V6", "url": "https://www.orthodb.org/?gene=A0A1D5P5V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13609", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13609", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_429403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_429403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P5V6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGCVGSHHDSSGSLNENSDGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKGDLETLDIPDPPPNSGHECQLRLRLSTGKDLKLMVRSMDTVYHMKRRLHAVEGVEPGSQRWFFSGRPLADKMKLEELKIPKDYVVQVIVSQPLANPTPVEN", "length": 234, "header": "tr|A0A1D5P5V6-1|A0A1D5P5V6_CHICK Isoform 1 of Ubiquitin domain containing 2 OS=Gallus gallus OX=9031 GN=UBTD2 PE=4 SV=1 CANONICAL=A0A1D5P5V6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5V6/entry", "sequence": { "sequence": "MGGCVGSHHDSSGSLNENSDGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKGDLETLDIPDPPPNSGHECQLRLRLSTGKDLKLMVRSMDTVYHMKRRLHAVEGVEPGSQRWFFSGRPLADKMKLEELKIPKDYVVQVIVSQPLANPTPVEN", "length": 234, "header": "tr|A0A1D5P5V6-1|A0A1D5P5V6_CHICK Isoform 1 of Ubiquitin domain containing 2 OS=Gallus gallus OX=9031 GN=UBTD2 PE=4 SV=1 CANONICAL=A0A1D5P5V6-1" }, "locus": { "chromosome": "13", "start_pos": 8409491, "end_pos": 8362666, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029501.1", "url": "https://www.ensembl.org/id/ENSGALT00010029501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017145.1", "url": "https://www.ensembl.org/id/ENSGALP00010017145.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416202", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416202", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LVF9-1", "protein_name": "Ubiquitin domain containing 2", "gene_name": "Ubtd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGCVGAQHDSSGSLNENSDGTGGLDLPIRSAGLAVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPSSGHESQLRLRLSTGKDLKLVVRSTDTVFHMKRRLHATEGVEPGSQRWFFSGRPLTDKMKLEELKIPKDYVVQVIVSQPVQNPAPVEN", "length": 246 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LIF4-1", "protein_name": "Ubiquitin domain containing 2", "gene_name": "UBTD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGCVGAQHDSSGSLNENSEGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPDPPPNSGYESQLRLRLSTGKDLKLVVRSTDTVYHMKRRLHAAEGVEPASQRWFFSGRPLTDKMKLEELKIPKDYVVQVIMSQPLQSPTPVEN", "length": 234 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5EAE3-1", "protein_name": "Ubiquitin domain-containing protein 2", "gene_name": "UBTD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGCVGAQHDSSGSLNENSEGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGYESQLRLRLSTGKDLKLVVRSTDTVYHMKRRLHAAEGVEPASQRWFFSGRPLTDKMRLEELKIPKDYVVQVIMSQPLQNPTPVEN", "length": 234 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DG43-1", "protein_name": "Ubiquitin domain-containing protein 2", "gene_name": "ubtd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGCVGSHHDSSGSLNENSDGTGVALGRNQPLKREKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAQAFESNDHELAQAIIDGASITLPHGALTECYDELGNRYQLPVYCLSPPVNMIEEKSESETIEVPEAPASEGQECQLRLRLSTGRDLRLAVRTSDSVQQMKRRLQTQEGVAATSQRWFFSGRPLTDKMKLEELKISRDYVVQVIVSQPPTTPPLPQNPTPVEN", "length": 240 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PGH0-1", "protein_name": "Ubiquitin domain-containing protein 2", "gene_name": "Ubtd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGCVGAQHDSSGSLNENSDGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGHESQLRLRLSTGKDLRLVVRSTDTVFHMKRRLHATEGVEPGSQRWFFSGRPLTDKMKLEELKIPKDYVVQVIVSQPVQTPTPVEN", "length": 234 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUN7-1", "protein_name": "Ubiquitin domain-containing protein 2", "gene_name": "UBTD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGCVGAQHDSSGSLNENSEGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGYECQLRLRLSTGKDLKLVVRSTDTVFHMKRRLHAAEGVEPGSQRWFFSGRPLTDKMKFEELKIPKDYVVQVIVSQPVQNPTPVEN", "length": 234 }, "evidence": [ { "id": "A0A1D5P5V6", "url": "https://omabrowser.org/oma/group/A0A1D5P5V6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P5V6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 234, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P5V6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P5V6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P602-1", "uniprot_ac": "A0A1D5P602", "uniprot_id": "A0A1D5P602_CHICK", "mass": { "chemical_mass": 10306.0, "monoisotopic_mass": 10306.0 }, "refseq": { "ac": "NP_001338380", "name": "methionine adenosyltransferase 2A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" }, "gene_names": [ { "name": "MAT2A", "type": "recommended", "evidence": [ { "id": "A0A1D5P602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P602" } ] }, { "name": "EDMTF1", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] }, { "name": "EDMTF2", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] }, { "name": "MAT2A", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] } ], "protein_names": [ { "name": "Methionine adenosyltransferase 2A", "type": "synonym", "evidence": [ { "id": "A0A1D5P602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P602/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein starting with MTF motif 1", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] }, { "name": "epidermal differentiation protein starting with MTF motif 3-like", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] }, { "name": "methionine adenosyltransferase 2A", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] }, { "name": "methionine adenosyltransferase like 1", "type": "synonym", "evidence": [ { "id": "NP_001338380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3109051, SAMN02738215 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On or before Dec 9, 2021 this sequence version replaced NP_001338381.1, NP_001338380.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001338380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338380" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P602", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P602" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAT2A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P602", "locus": { "chromosome": "25", "start_pos": 1605799, "end_pos": 1604597, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028757", "url": "https://www.ensembl.org/id/ENSGALG00010028757" } ] } } ], "crossref": [ { "id": "A0A1D5P602", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P602", "database": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052589.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040541996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6B3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6B3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121111906", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6B3", "locus": {} } ], "crossref": [ { "id": "A0A1D5P6B3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P6B3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031016", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031016", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": 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695, "end_pos": 697 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P6M0-1", "uniprot_ac": "A0A1D5P6M0", "uniprot_id": "A0A1D5P6M0_CHICK", "mass": { "chemical_mass": 29841.0, "monoisotopic_mass": 29841.0 }, "refseq": { "ac": "NP_989832", "name": "protein shisa-2 homolog precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" }, "gene_names": [ { "name": "SHISA2", "type": "recommended", "evidence": [ { "id": "A0A1D5P6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ] }, { "name": "SHISA2", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "name": "SHISA", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "name": "TMEM46", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] } ], "protein_names": [ { "name": "Shisa family member 2", "type": "synonym", "evidence": [ { "id": "A0A1D5P6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0/entry#names_and_taxonomy" } ] }, { "name": "protein shisa-2 homolog precursor", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "name": "protein shisa-2 homolog", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "name": "shisa homolog 2", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "name": "transmembrane protein 46", "type": "synonym", "evidence": [ { "id": "NP_989832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF257354.1, DQ342343.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08016664 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000027.1. On Sep 23, 2021 this sequence version replaced NP_989832.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ] }, { "annotation": "The Shisa family genes are typically expressed in tissues known to require the modulation of Wnt and FGF signaling", "evidence": [ { "database": "RefSeq", "id": "NP_989832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" }, { "database": "PubMed", "id": "16773659", "url": "https://glygen.org/publication/PubMed/16773659" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHISA2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0", "locus": { "chromosome": "1", "start_pos": 176876763, "end_pos": 176880617, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005970", "url": "https://www.ensembl.org/id/ENSGALG00010005970" } ] } } ], "crossref": [ { "id": "A0A1D5P6M0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P6M0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043035", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395162", "url": "https://www.ncbi.nlm.nih.gov/gene/395162", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395162", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395162", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YAHPVSP", "url": "https://omabrowser.org/oma/group/YAHPVSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P6M0", "url": "https://www.orthodb.org/?gene=A0A1D5P6M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGGRCSLLLAALGWLLPAGAAGSGEYCHGWLDGQGGWRDGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRRQGGGEQGRPRDGPDGAAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQEPQQSHAPAGARLMETIPMIASTGASRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQFLHPPYVGYAVPHDAVPLAPVPQFLDGLQGGYRQIQSPYPHAGGEQKMYPAVTV", "length": 284, "header": "tr|A0A1D5P6M0-1|A0A1D5P6M0_CHICK Isoform 1 of Shisa family member 2 OS=Gallus gallus OX=9031 GN=SHISA2 PE=4 SV=2 CANONICAL=A0A1D5P6M0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P6M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0/entry", "sequence": { "sequence": "MWGGRCSLLLAALGWLLPAGAAGSGEYCHGWLDGQGGWRDGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRRQGGGEQGRPRDGPDGAAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQEPQQSHAPAGARLMETIPMIASTGASRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQFLHPPYVGYAVPHDAVPLAPVPQFLDGLQGGYRQIQSPYPHAGGEQKMYPAVTV", "length": 284, "header": "tr|A0A1D5P6M0-1|A0A1D5P6M0_CHICK Isoform 1 of Shisa family member 2 OS=Gallus gallus OX=9031 GN=SHISA2 PE=4 SV=2 CANONICAL=A0A1D5P6M0-1" }, "locus": { "chromosome": "1", "start_pos": 176880392, "end_pos": 176878401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014270.1", "url": "https://www.ensembl.org/id/ENSGALT00010014270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008377.1", "url": "https://www.ensembl.org/id/ENSGALP00010008377.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Comparative expression of mouse and chicken Shisa homologues during early development.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2006", "authors": "Filipe M, Goncalves L, Bento M, Silva AC, Belo JA", "evidence": [ { "database": "RefSeq", "id": "NP_989832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989832" } ], "reference": [ { "type": "PubMed", "id": "16773659", "url": "https://glygen.org/publication/PubMed/16773659" } ] } ], "pathway": [ { "id": "gga:395162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395162", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QPA0-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "SHISA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWAGCHPDAASLLRLLLAALLAAGALASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSADARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIVLGSLVAACCCRCLRPKQEPQLSRAPGGPRLVETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPFVGYTVQPDSVPLTPVPPFLDGLQTGYRQLQAPFPHTNSEQKMYPAVTV", "length": 289 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZWR8-1", "protein_name": "Shisa family member 2", "gene_name": "Shisa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPSFAHTNSEQKMFPAVTV", "length": 295 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FEC3-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "shisa2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRGCTGFPMAVTVVLTLLTVMNVKASGEYCHGWHDAQGVWKDGFQCPERFDTPDAIICCGKCELRYCCSSTEARLDQGTCDNDKQTQETNTGSKDDKNSGAVPIYVPFLIVGSVFVAFVLVGSVVAVCCCRCLRPKQEPTSGGGSGGASSSARVLETIPMMASTGTSRGSSSRQSSTATSSSSSAPPAAPRPAPAPLLRAQASCCLPPDASVYVNMPTNFSVLNCQQATQILPHQGQFLHPQYIGFAHPVAPAAAFLDPTQAGYRPLQSPFPPPTSVASVASITGDHKHPPVTM", "length": 294 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RTL1-1", "protein_name": "Shisa family member 2", "gene_name": "SHISA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWGGRRPAASSRDAASFLRLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIIVGSLVAACCCRCLRPKQEPPQSRAPGGPRLTETIPMIPSASTSRGSSSRQSSTATSSSSSANSGARAPPTRSQTNCCLPEGPLNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHAPYVGYTVQHDSVPLTPVPPFLDGLQTGYRQIQAPFPHTSSEQKMFPAVTV", "length": 294 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6UWI4-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "SHISA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWGARRSSVSSSWNAASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPYVGYTVQHDSVPMTAVPPFMDGLQPGYRQIQSPFPHTNSEQKMYPAVTV", "length": 295 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8QZV2-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "Shisa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGANRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPPFAHTNSEQKMFPAVTV", "length": 295 }, "evidence": [ { "id": "A0A1D5P6M0", "url": "https://omabrowser.org/oma/group/A0A1D5P6M0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040037", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6M0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P6M0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P6M0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P6M0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P6M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6M0" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 80, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 283 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQJ3-1", "uniprot_ac": "A0A1D5PQJ3", "uniprot_id": "A0A1D5PQJ3_CHICK", "mass": { "chemical_mass": 49464.0, "monoisotopic_mass": 49464.0 }, "refseq": { "ac": "XP_015146183", "name": "divergent protein kinase domain 1A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146183" }, "gene_names": [ { "name": "FAM69A", "type": "recommended", "evidence": [ { "id": "A0A1D5PQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3" } ] }, { "name": "FAM69A", "type": "synonym", "evidence": [ { "id": "XP_015146183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146183" } ] } ], "protein_names": [ { "name": "Divergent protein kinase domain 1A", "type": "synonym", "evidence": [ { "id": "A0A1D5PQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3/entry#names_and_taxonomy" } ] }, { "name": "divergent protein kinase domain 1A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015146183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146183" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146183" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM69A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3", "locus": {} } ], "crossref": [ { "id": "A0A1D5PQJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005918", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "429087", "url": "https://www.ncbi.nlm.nih.gov/gene/429087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429087", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMRIKYL", "url": "https://omabrowser.org/oma/group/YMRIKYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQJ3", "url": "https://www.orthodb.org/?gene=A0A1D5PQJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146183", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P6Q4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P6Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N905", "url": "https://www.uniprot.org/uniprotkb/F1N905", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N905-1", "url": "https://www.uniprot.org/uniprotkb/F1N905-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRLFAGAWLRKPHHAQVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 428, "header": "tr|A0A1D5PQJ3-1|A0A1D5PQJ3_CHICK Isoform 1 of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=2 CANONICAL=A0A1D5PQJ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P6Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q4/entry", "sequence": { "sequence": "MSRYHKDRKVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 419, "header": "tr|A0A1D5P6Q4-1|A0A1D5PQJ3_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=2 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13768047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052953.1", "url": "https://www.ensembl.org/id/ENSGALT00010052953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031859.1", "url": "https://www.ensembl.org/id/ENSGALP00010031859.1" } ] } }, { "isoform_ac": "A0A1D5PQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3/entry", "sequence": { "sequence": "MARRLFAGAWLRKPHHAQVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 428, "header": "tr|A0A1D5PQJ3-1|A0A1D5PQJ3_CHICK Isoform 1 of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=2 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13768733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052940.1", "url": "https://www.ensembl.org/id/ENSGALT00010052940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031846.1", "url": "https://www.ensembl.org/id/ENSGALP00010031846.1" } ] } }, { "isoform_ac": "A0A8V0ZEV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV0/entry", "sequence": { "sequence": "MARRLFAGAWLRKPHHAQVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 369, "header": "tr|A0A8V0ZEV0-1|A0A8V0ZEV0_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=1 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13768733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052916.1", "url": "https://www.ensembl.org/id/ENSGALT00010052916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031823.1", "url": "https://www.ensembl.org/id/ENSGALP00010031823.1" } ] } }, { "isoform_ac": "A0A8V0ZMB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMB6/entry", "sequence": { "sequence": "MARRLFAGAWLRKPHHAQCDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 383, "header": "tr|A0A8V0ZMB6-1|A0A8V0ZMB6_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=1 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13768733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052945.1", "url": "https://www.ensembl.org/id/ENSGALT00010052945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031852.1", "url": "https://www.ensembl.org/id/ENSGALP00010031852.1" } ] } }, { "isoform_ac": "A0A8V0ZMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD0/entry", "sequence": { "sequence": "MCFAGNTCVPEVFCCKPASVAASEHSMSRYHKDRKVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 445, "header": "tr|A0A8V0ZMD0-1|A0A8V0ZMD0_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=1 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13761116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052956.1", "url": "https://www.ensembl.org/id/ENSGALT00010052956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031862.1", "url": "https://www.ensembl.org/id/ENSGALP00010031862.1" } ] } }, { "isoform_ac": "A0A8V0ZSQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSQ4/entry", "sequence": { "sequence": "MSQLRSTVQVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 419, "header": "tr|A0A8V0ZSQ4-1|A0A1D5PQJ3_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=1 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13769603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052933.1", "url": "https://www.ensembl.org/id/ENSGALT00010052933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031839.1", "url": "https://www.ensembl.org/id/ENSGALP00010031839.1" } ] } }, { "isoform_ac": "F1N905-1", "url": "https://www.uniprot.org/uniprotkb/F1N905/entry", "sequence": { "sequence": "MVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 411, "header": "tr|F1N905-1|A0A1D5PQJ3_CHICK Computationally mapped isoform of Divergent protein kinase domain 1A OS=Gallus gallus OX=9031 GN=FAM69A PE=3 SV=4 CANONICAL=A0A1D5PQJ3-1" }, "locus": { "chromosome": "8", "start_pos": 13781182, "end_pos": 13773700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052950.1", "url": "https://www.ensembl.org/id/ENSGALT00010052950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031856.1", "url": "https://www.ensembl.org/id/ENSGALP00010031856.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FCF0-1", "protein_name": "Divergent protein kinase domain 1A isoform X1", "gene_name": "dipk1ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLIAREVRRLRSITLFIIRSPYGEKHPGLVSAVKCGVSIMARGLIPWIWLKRPVYIQARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 468 }, "evidence": [ { "id": "A0A1D5PQJ3", "url": "https://omabrowser.org/oma/group/A0A1D5PQJ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S4G2-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "DIPK1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARSLCPGAWLRKPRYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSAYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTAKQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "A0A1D5PQJ3", "url": "https://omabrowser.org/oma/group/A0A1D5PQJ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HED0-1", "protein_name": "Divergent protein kinase domain 1A isoform X1", "gene_name": "Dipk1a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRVKYLFFSWLVVFVGSWVIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACSSLCVTETLYLGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQTLHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 405 }, "evidence": [ { "id": "A0A1D5PQJ3", "url": "https://omabrowser.org/oma/group/A0A1D5PQJ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5T7M9-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "DIPK1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "A0A1D5PQJ3", "url": "https://omabrowser.org/oma/group/A0A1D5PQJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6I7-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "Dipk1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARSLCAGAWLRKPHYLQARLSYMRVKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSNKPSNQMYLGVWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVMELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDLSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "A0A1D5PQJ3", "url": "https://omabrowser.org/oma/group/A0A1D5PQJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQJ3" }, { "id": "SM01299", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM69 N-terminal", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 177, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P6T2-1", "uniprot_ac": "A0A1D5P6T2", "uniprot_id": "A0A1D5P6T2_CHICK", "mass": { "chemical_mass": 55781.0, "monoisotopic_mass": 55781.0 }, "refseq": { "ac": "XP_015138330", "name": "Y+L amino acid transporter 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138330" }, "gene_names": [ { "name": "SLC7A7", "type": "recommended", "evidence": [ { "id": "A0A1D5P6T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ] }, { "name": "SLC7A7", "type": "synonym", "evidence": [ { "id": "XP_015138330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138330" } ] } ], "protein_names": [ { "name": "Solute carrier family 7 member 7", "type": "synonym", "evidence": [ { "id": "A0A1D5P6T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2/entry#names_and_taxonomy" } ] }, { "name": "Y+L amino acid transporter 2", "type": "synonym", "evidence": [ { "id": "XP_015138330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138330" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138330" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC7A7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2", "locus": {} } ], "crossref": [ { "id": "A0A1D5P6T2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P6T2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034806", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420216", "url": "https://www.ncbi.nlm.nih.gov/gene/420216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420216", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420216", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYGHYCA", "url": "https://omabrowser.org/oma/group/RYGHYCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P6T2", "url": "https://www.orthodb.org/?gene=A0A1D5P6T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PTC5", "url": "https://www.orthodb.org/?gene=A0A1D5PTC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMS1", "url": "https://www.orthodb.org/?gene=A0A8V0YMS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSWQISCKKKSRSKNGNAEMDDTADTSEKLRMKKEITLLNGVSLIVGNMIGSGIFVSPRGVLMYSASYGLSLIIWALGGMFSLFGALCYAELGASIVKSGASYAYILEAFGAFVAFIRLWSSLLIIEPTTQAVIAITFGNYIVQPIFPHCEPPYDAVRLIAAACICSLTFINCVNVKWGTRVQDIFTYAKLVALVVVISVGLYKIGKGETENLRAPFEGSATDPGMIALALYSALFSYAGWDTLNYVTEEMQNPERNLPLSIAISMPIVTIIYLLTNIAYYVVLDMSTLLTSDAVAVAFGIETLGYAKWIIPIAVAMSCYSGLNSSIIAASRLFYVGAREGHLPDSLSLIHVKCFTPVPALLFNGLMTLLYLLVEDVFLLINYYCFNYWLFVGLSIAGLIYLRYTQPRRPRPIKLNLFIPIIYCLCSLFLVIVPLYSDTINSLIGIGIALSGIPAYYLGVHLPFEKRPKWLQWLSVTTTKFVQLLFYCALSELDMEPTKAESK", "length": 505, "header": "tr|A0A1D5P6T2-1|A0A1D5P6T2_CHICK Isoform 1 of Solute carrier family 7 member 7 OS=Gallus gallus OX=9031 GN=SLC7A7 PE=3 SV=1 CANONICAL=A0A1D5P6T2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2/entry", "sequence": { "sequence": "MTTSWQISCKKKSRSKNGNAEMDDTADTSEKLRMKKEITLLNGVSLIVGNMIGSGIFVSPRGVLMYSASYGLSLIIWALGGMFSLFGALCYAELGASIVKSGASYAYILEAFGAFVAFIRLWSSLLIIEPTTQAVIAITFGNYIVQPIFPHCEPPYDAVRLIAAACICSLTFINCVNVKWGTRVQDIFTYAKLVALVVVISVGLYKIGKGETENLRAPFEGSATDPGMIALALYSALFSYAGWDTLNYVTEEMQNPERNLPLSIAISMPIVTIIYLLTNIAYYVVLDMSTLLTSDAVAVAFGIETLGYAKWIIPIAVAMSCYSGLNSSIIAASRLFYVGAREGHLPDSLSLIHVKCFTPVPALLFNGLMTLLYLLVEDVFLLINYYCFNYWLFVGLSIAGLIYLRYTQPRRPRPIKLNLFIPIIYCLCSLFLVIVPLYSDTINSLIGIGIALSGIPAYYLGVHLPFEKRPKWLQWLSVTTTKFVQLLFYCALSELDMEPTKAESK", "length": 505, "header": "tr|A0A1D5P6T2-1|A0A1D5P6T2_CHICK Isoform 1 of Solute carrier family 7 member 7 OS=Gallus gallus OX=9031 GN=SLC7A7 PE=3 SV=1 CANONICAL=A0A1D5P6T2-1" }, "locus": { "chromosome": "2", "start_pos": 123898020, "end_pos": 123885460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029933.1", "url": "https://www.ensembl.org/id/ENSGALT00010029933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017419.1", "url": "https://www.ensembl.org/id/ENSGALP00010017419.1" } ] } }, { "isoform_ac": "A0A1D5PTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTC5/entry", "sequence": { "sequence": "MTTSWQISCKKKSRSKNGNAEMDDTADTSEKLRMKKEITLLNGVSLIVGNMIGSGIFVSPRGVLMYSASYGLSLIIWALGGMFSLFGALCYAELGASIVKSGASYAYILEAFGAFVAFIRLWSSLLIIEPTTQAVIAITFGNYIVQPIFPHCEPPYDAVRLIAAACICK", "length": 169, "header": "tr|A0A1D5PTC5-1|A0A1D5PTC5_CHICK Computationally mapped isoform of Solute carrier family 7 member 7 OS=Gallus gallus OX=9031 GN=SLC7A7 PE=4 SV=2 CANONICAL=A0A1D5P6T2-1" }, "locus": { "chromosome": "2", "start_pos": 123898460, "end_pos": 123897954, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029944.1", "url": "https://www.ensembl.org/id/ENSGALT00010029944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017422.1", "url": "https://www.ensembl.org/id/ENSGALP00010017422.1" } ] } }, { "isoform_ac": "A0A8V0YMS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMS1/entry", "sequence": { "sequence": "MTTSWQISCKKKSRSKNGNAEMDDTADTSEKLRMKKEITLLNGVSLIVGNMIGSGIFVSPRGVLMYSASYGLSLIIWALGGMFSLFGALCYAELGASIVKSGASYAYILEAFGAFVAFIRLWSSLLIIEPTTQAVIAITFGNYIVQPIFPHCEPPYDAVRLIAAACI", "length": 167, "header": "tr|A0A8V0YMS1-1|A0A1D5P6T2_CHICK Computationally mapped isoform of Solute carrier family 7 member 7 OS=Gallus gallus OX=9031 GN=SLC7A7 PE=3 SV=1 CANONICAL=A0A1D5P6T2-1" }, "locus": { "chromosome": "2", "start_pos": 123885960, "end_pos": 123885460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029926.1", "url": "https://www.ensembl.org/id/ENSGALT00010029926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017416.1", "url": "https://www.ensembl.org/id/ENSGALP00010017416.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420216", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P6T2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6T2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P6T2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 505, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P6T2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P6T2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P768-1", "uniprot_ac": "A0A1D5P768", "uniprot_id": "A0A1D5P768_CHICK", "mass": { "chemical_mass": 112301.0, "monoisotopic_mass": 112301.0 }, "refseq": { "ac": "NP_001025835", "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835" }, "gene_names": [ { "name": "NAA25", "type": "recommended", "evidence": [ { "id": "A0A1D5P768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ] }, { "name": "C12orf30", "type": "synonym", "evidence": [ { "id": "NP_001025835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835" } ] }, { "name": "NAA25", "type": "synonym", "evidence": [ { "id": "NP_001025835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "type": "recommended", "evidence": [ { "id": "A0A1D5P768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial distribution and morphology protein 20", "type": "synonym", "evidence": [ { "id": "A0A1D5P768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768/entry#names_and_taxonomy" } ] }, { "name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "type": "synonym", "evidence": [ { "id": "NP_001025835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835" } ] }, { "name": "N-terminal acetyltransferase B complex subunit MDM20", "type": "synonym", "evidence": [ { "id": "A0A1D5P768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768/entry#names_and_taxonomy" } ] }, { "name": "N-terminal acetyltransferase B complex subunit NAA25", "type": "synonym", "evidence": [ { "id": "A0A1D5P768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851660.1, SRR13267649.22565.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Sep 9, 2010 this sequence version replaced NP_001025835.1. Sequence Note: This RefSeq record was created from transcripts from multiple strains and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001025835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835" } ] }, { "annotation": "Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. May play a role in normal cell-cycle progression.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768#function" }, { "database": "UniProtKB", "id": "ARBA00057542", "url": "https://www.uniprot.org/uniprotkb/ARBA00057542#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAA25", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768", "locus": { "chromosome": "15", "start_pos": 6282012, "end_pos": 6307616, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025976", "url": "https://www.ensembl.org/id/ENSGALG00010025976" } ] } } ], "crossref": [ { "id": "A0A1D5P768", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P768", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041821", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416883", "url": "https://www.ncbi.nlm.nih.gov/gene/416883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416883", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416883", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKRREHQ", "url": "https://omabrowser.org/oma/group/WKRREHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P768", "url": "https://www.orthodb.org/?gene=A0A1D5P768", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P768-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQDEAYALAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLEKYQEALDVVRGKLGEKLTSELQSRENKCMAMYKKLCRWPECNALSRRLLLKNSDDWQFYITYFDSVFQLIDESWTPPLEEEHSLEGEVHYSIEQAVKFIEERITEESKSTRPLRGPYLAKLELIRRLRCRGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPSSQYTKFISQLLEVIPLSSTAESEIALPADIKALQQHLCVVQLSRLLGIYHAMDKMQKLTVVRELMLRYHHGLEFGKSCLKTELQFSDYYCLLAVHLLLDLWLEEGEEMAVWQCLTLLEEGLSHSPSNAQFKLLLIRIYCRLGAFEPVAELYSSLDAKHIQHDTIGYLLTRYAEALGHYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNSSLHFAQVRTERMLLDLLLEANISSSLEESIKSMSLSPEEDDIPWKDLRDNRDLTVLFNWDPKDRDISEEHRKLSLEEETLWLRIRSLTLRLVSGLPTLSHSIQPKNSEKTAENGVSSKIDTIRSLLQQLEAAVDSGKKFLEQKIQYPVLGPPPTRMAGFFSNGSCQCQTSLFYLVSDIYELDTNGLEDSAEVQERIGNSFKSLIERLTDLFNKCKGDLIEVRDGTLKTQPNLLENLVFFVETISITQWVSSYCDGVLRPFKSNLQKKKKKKKETNVAMPPVFTHFLDYVTELQTLTSNVIDHIKGLEIILTALKLEELSLKDTLLLQEEKKFTKTVQGKVQSSYHHSVQEIGELLKKRLDTIKKLKI", "length": 972, "header": "tr|A0A1D5P768-1|A0A1D5P768_CHICK Isoform 1 of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA25 PE=1 SV=1 CANONICAL=A0A1D5P768-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P768-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768/entry", "sequence": { "sequence": "MAARGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQDEAYALAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLEKYQEALDVVRGKLGEKLTSELQSRENKCMAMYKKLCRWPECNALSRRLLLKNSDDWQFYITYFDSVFQLIDESWTPPLEEEHSLEGEVHYSIEQAVKFIEERITEESKSTRPLRGPYLAKLELIRRLRCRGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPSSQYTKFISQLLEVIPLSSTAESEIALPADIKALQQHLCVVQLSRLLGIYHAMDKMQKLTVVRELMLRYHHGLEFGKSCLKTELQFSDYYCLLAVHLLLDLWLEEGEEMAVWQCLTLLEEGLSHSPSNAQFKLLLIRIYCRLGAFEPVAELYSSLDAKHIQHDTIGYLLTRYAEALGHYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNSSLHFAQVRTERMLLDLLLEANISSSLEESIKSMSLSPEEDDIPWKDLRDNRDLTVLFNWDPKDRDISEEHRKLSLEEETLWLRIRSLTLRLVSGLPTLSHSIQPKNSEKTAENGVSSKIDTIRSLLQQLEAAVDSGKKFLEQKIQYPVLGPPPTRMAGFFSNGSCQCQTSLFYLVSDIYELDTNGLEDSAEVQERIGNSFKSLIERLTDLFNKCKGDLIEVRDGTLKTQPNLLENLVFFVETISITQWVSSYCDGVLRPFKSNLQKKKKKKKETNVAMPPVFTHFLDYVTELQTLTSNVIDHIKGLEIILTALKLEELSLKDTLLLQEEKKFTKTVQGKVQSSYHHSVQEIGELLKKRLDTIKKLKI", "length": 972, "header": "tr|A0A1D5P768-1|A0A1D5P768_CHICK Isoform 1 of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA25 PE=1 SV=1 CANONICAL=A0A1D5P768-1" }, "locus": { "chromosome": "15", "start_pos": 6307597, "end_pos": 6283673, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063353.1", "url": "https://www.ensembl.org/id/ENSGALT00010063353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039107.1", "url": "https://www.ensembl.org/id/ENSGALP00010039107.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416883", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416883", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZT74-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "NAA25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKSCLKTELQFSDYYCLLAVHVLIDIWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLEDTVEIQERVENSLKSLLEQLKDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H283-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEAAQSARHVRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHIMDKNQKLGVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLTDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRTLTLRLISGLPSLTHPVEPKNSEKTSENGVSSRIDILRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVRSFHLVSDVYELDTSGLEGTVDIQERIENSLTSLLELLKGVFSTCKGELLEVTDGNVKTQPAILENLVFFVETVSVILWVSSYCESVLRPYKLNIQKKKKKKKETSIIMPPVFTTFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELTLEDTCISPEERKFSKTVQGKVQSSYLHSLLEIGELLRKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q14CX7-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "NAA25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWSPPAEGEHSLEGEVHYSAEKAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKTCLKTELQFSDYYCLLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETLWLRIRSLTLRLISGLPSLNHPVEPKNSEKTAENGVSSRIDILRLLLQQLEATLETGKRFIEKDIQYPFLGPVPTRMGGFFNSGCSQCQISSFYLVNDIYELDTSGLEDTMEIQERIENSFKSLLDQLKDVFSKCKGDLLEVKDGNLKTHPTLLENLVFFVETISVILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSPEERKFSKTVQGKVQSSYLHSLLEMGELLKKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6QI44-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEFRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISALPSLTHPVEPRNSEKTSENGVSSRVDVLRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVHSFHLVSDVYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVKDGNVKTQPAVLENLVFFVETISIVLWVSSYCESVLRPYKLNIQKKKKKKKETSIVMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALKLEELTLEDTSISPVNLSNCHVLSVRRRDPGSYWKLGAVEPMCADVCPSVQI", "length": 970 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BWZ3-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKSQKLDVVKELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDVWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISISLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLTHPVEPKNSEKMSENGVSSRIDILRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVQSFHLVSDMYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVTDGNVKTQPAVLENLVFFVETISVILWVSSYCESVLRPYKLNIQKKKKKKKETSIIMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALRLEELTLEETSISTEERKFSKTVQGKVQSSYLHSLLETGELLRKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDQ7-1", "protein_name": "Phagocyte signaling-impaired protein", "gene_name": "psidin", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGAPVSMKFELLKELGNWRELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDKDSLARCQEFLQRIIDSSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVEATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK", "length": 948 }, "evidence": [ { "id": "A0A1D5P768", "url": "https://omabrowser.org/oma/group/A0A1D5P768/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "pmid": "" }, { "name": "NatB complex", "id": "GO:0031416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031416", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P768", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P768" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P768-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 972, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P768-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P768" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 767, "end_pos": 769 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P7C6-1", "uniprot_ac": "A0A1D5P7C6", "uniprot_id": "A0A1D5P7C6_CHICK", "mass": { "chemical_mass": 43780.0, "monoisotopic_mass": 43780.0 }, "refseq": { "ac": "XP_015155794", "name": "proliferation-associated protein 2G4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155794" }, "gene_names": [ { "name": "PA2G4", "type": "recommended", "evidence": [ { "id": "A0A1D5P7C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ] }, { "name": "PA2G4", "type": "synonym", "evidence": [ { "id": "XP_015155794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155794" } ] } ], "protein_names": [ { "name": "Proliferation-associated protein 2G4", "type": "recommended", "evidence": [ { "id": "A0A1D5P7C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6/entry#names_and_taxonomy" } ] }, { "name": "proliferation-associated protein 2G4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155794" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155794" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PA2G4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6", "locus": { "chromosome": "34", "start_pos": 1401504, "end_pos": 1391044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024839", "url": "https://www.ensembl.org/id/ENSGALG00010024839" } ] } } ], "crossref": [ { "id": "A0A1D5P7C6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P7C6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034218", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01089", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01089", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425279", "url": "https://www.ncbi.nlm.nih.gov/gene/425279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425279", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SRMFYSE", "url": "https://omabrowser.org/oma/group/SRMFYSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7C6", "url": "https://www.orthodb.org/?gene=A0A1D5P7C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Q0", "url": "https://www.orthodb.org/?gene=A0A8V1A7Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10804:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10804:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGEEEAAELTIAEDLVVTKYKMGGDIANRVLRAVVEEANSGASVLCLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKDGDLVKIDLGVHVDGFIANVAHSFVINASKEKPVSGRKADVIKAAHLCAEAALRLVKPGNQNTQVTDAWNKIAHSFHCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDTMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPELYKSEFEVQDGELKALLQSSASRKTQKKKKKKASKNAENATTGETAEENEAGD", "length": 394, "header": "tr|A0A1D5P7C6-1|A0A1D5P7C6_CHICK Isoform 1 of Proliferation-associated protein 2G4 OS=Gallus gallus OX=9031 GN=PA2G4 PE=1 SV=1 CANONICAL=A0A1D5P7C6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6/entry", "sequence": { "sequence": "MSGEEEAAELTIAEDLVVTKYKMGGDIANRVLRAVVEEANSGASVLCLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKDGDLVKIDLGVHVDGFIANVAHSFVINASKEKPVSGRKADVIKAAHLCAEAALRLVKPGNQNTQVTDAWNKIAHSFHCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDTMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPELYKSEFEVQDGELKALLQSSASRKTQKKKKKKASKNAENATTGETAEENEAGD", "length": 394, "header": "tr|A0A1D5P7C6-1|A0A1D5P7C6_CHICK Isoform 1 of Proliferation-associated protein 2G4 OS=Gallus gallus OX=9031 GN=PA2G4 PE=1 SV=1 CANONICAL=A0A1D5P7C6-1" }, "locus": { "chromosome": "34", "start_pos": 1400114, "end_pos": 1391151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060638.1", "url": "https://www.ensembl.org/id/ENSGALT00010060638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037397.1", "url": "https://www.ensembl.org/id/ENSGALP00010037397.1" } ] } }, { "isoform_ac": "A0A8V1A7Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q0/entry", "sequence": { "sequence": "MRCPRPARISPVPPGVLRAVVEEANSGASVLCLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKDGDLVKIDLGVHVDGFIANVAHSFVINASKEKPVSGRKADVIKAAHLCAEAALRLVKPGNQNTQVTDAWNKIAHSFHCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDTMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPELYKSEFEVQDGELKALLQSSASRKTQKKKKKKASKNAENATTGETAEENEAGD", "length": 379, "header": "tr|A0A8V1A7Q0-1|A0A1D5P7C6_CHICK Computationally mapped isoform of Proliferation-associated protein 2G4 OS=Gallus gallus OX=9031 GN=PA2G4 PE=1 SV=1 CANONICAL=A0A1D5P7C6-1" }, "locus": { "chromosome": "34", "start_pos": 1400114, "end_pos": 1391568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060634.1", "url": "https://www.ensembl.org/id/ENSGALT00010060634.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037393.1", "url": "https://www.ensembl.org/id/ENSGALP00010037393.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425279", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q1ZXG4-1", "protein_name": "Proliferation-associated protein A", "gene_name": "prlA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKDQEIKEEAPVAIEDLSNPVVVDSYNAAGIIANNAIKHVISKCVVGALVVDICQYGDDFIEAEAAKTFTKRKNLEKGIAFPTCVSVNNCVGHFSPLKGNTRTLKQGDVVKIDLGCHIDGYIAVGAHTIIIGNTSAESMTGKVADAICAAHYALEAALRMIRPGKTSNEVTQVIEKISDMYGVTSVSGILSHELKRFIIDGEKVIFSKNEPSQKIQTYEFQENEVYCIDIVMSTGEGKAREEADRPTIYRRNLDSTYKLKSKASRDFKDQIVKRYSALPFPLRNFDEKVSKLGLVELVEHQVLAAYPVLFDRSGCEVVQFKTTVLVLPNGNHKLIGTEFPLPFVRSEFSVTDDAIKALIASPLKINKKAAKKASATTIDVKMQ", "length": 385 }, "evidence": [ { "id": "A0A1D5P7C6", "url": "https://omabrowser.org/oma/group/A0A1D5P7C6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VRP2-1", "protein_name": "Peptidase M24 domain-containing protein", "gene_name": "BEST:CK00496", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADVEKEPEKTIAEDLVVTKYKLAGEIVNKTLKAVIGLCVVDASVREICTQGDNQLTEETGKVYKKEKDLKKGIAFPTCLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGAHIDGFIAVAAHTIVVGAAADQKISGRQADVILAAYWAVQAALRLLKSGANNYSLTDAVQQISESYKCKPIEGMLSHELKQFKIDGEKTIIQNPSEAQRKEHEKCTFETYEVYAIDVIVSTGEGVGREKDTKVSIYKKSEENYMLKMKASRALLAEVKTKYGNMPFNIRSFEEETKARMGVVECVGHKMIEPFQVLYEKPSEIVAQFKHTVLLMPNGVNLVTGIPFEAENYVSEYSVAQEELKTLLAQPLGPVKGKGKGKKATAGAATKVETAPAVETKA", "length": 391 }, "evidence": [ { "id": "A0A1D5P7C6", "url": "https://omabrowser.org/oma/group/A0A1D5P7C6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7C6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P7C6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 394, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P7C6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P7C6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P7C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C6" }, { "id": "PF00557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M24", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 194, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 380, "end_pos": 382 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P7L2-1", "uniprot_ac": "A0A1D5P7L2", "uniprot_id": "A0A1D5P7L2_CHICK", "mass": { "chemical_mass": 62593.0, "monoisotopic_mass": 62593.0 }, "refseq": { "ac": "NP_001264412", "name": "hypermethylated in cancer 2 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264412" }, "gene_names": [ { "name": "HIC2", "type": "recommended", "evidence": [ { "id": "A0A1D5P7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ] }, { "name": "HIC2", "type": "synonym", "evidence": [ { "id": "NP_001264412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264412" } ] } ], "protein_names": [ { "name": "Hypermethylated in cancer 1 protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2/entry#names_and_taxonomy" } ] }, { "name": "Hypermethylated in cancer 2 protein", "type": "synonym", "evidence": [ { "id": "A0A1D5P7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2/entry#names_and_taxonomy" } ] }, { "name": "hypermethylated in cancer 2 protein", "type": "synonym", "evidence": [ { "id": "NP_001264412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264412" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX929888.1, BU253936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX929888.1. On or before Apr 10, 2013 this sequence version replaced XP_001232817.1, XP_415063.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from a transcript that is from a different strain than the reference genome strain because no transcript was available from the reference strain for the full length of the gene.", "evidence": [ { "database": "RefSeq", "id": "NP_001264412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264412" } ] }, { "annotation": "Transcriptional repressor.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2#function" }, { "database": "UniProtKB", "id": "ARBA00057867", "url": "https://www.uniprot.org/uniprotkb/ARBA00057867#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HIC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2", "locus": { "chromosome": "15", "start_pos": 248200, "end_pos": 330566, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024282", "url": "https://www.ensembl.org/id/ENSGALG00010024282" } ] } } ], "crossref": [ { "id": "ENSGALG00000033416", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033416", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416768", "url": "https://www.ncbi.nlm.nih.gov/gene/416768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416768", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGHNNHY", "url": "https://omabrowser.org/oma/group/TGHNNHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7L2", "url": "https://www.orthodb.org/?gene=A0A1D5P7L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPNHAKQLLLQLNQQRAKGFLCDVIIVVENALFRAHKNILAASSMYFKSLVLHDNLINLDTDMVNPTVFRQILDFIYTGKLLTTDQPGEQNFSALLTAASYLQLHDLAALCRKKLKRNSKSFAGKASGLGVGRSARSQRLSTASVIQARYSGSNEGLKGSHSKELSKGKLSDDEVFISSSNQENCHSLSRGASKNCGGGGSANGSTGDQELGLDLSKKSPSLPVAASHDDTQHSESQHGSPQSASVPAANSASSFDESGVGASHSIADSSDPMEMDLSEECHHSMTESSQRKGLRHSSRKKEWIKKDNAFDRKDGGKDRDEGEGLPNGILLGPLSKSVERSLAGSYGADLPYSCKEEVENGKENSDDSGQSESESGGHTSANYVYRQEGFEPVAYGDNLYVCIPCGKGFPSSEQLNAHVETHTEEDLYIKEEGTYGGKDEAEDLSNPNQSYSAESRPFKCSVCEKSYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACEECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPT", "length": 570, "header": "tr|A0A1D5P7L2-1|A0A1D5P7L2_CHICK Isoform 1 of Hypermethylated in cancer 1 protein OS=Gallus gallus OX=9031 GN=HIC2 PE=3 SV=1 CANONICAL=A0A1D5P7L2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2/entry", "sequence": { "sequence": "MELPNHAKQLLLQLNQQRAKGFLCDVIIVVENALFRAHKNILAASSMYFKSLVLHDNLINLDTDMVNPTVFRQILDFIYTGKLLTTDQPGEQNFSALLTAASYLQLHDLAALCRKKLKRNSKSFAGKASGLGVGRSARSQRLSTASVIQARYSGSNEGLKGSHSKELSKGKLSDDEVFISSSNQENCHSLSRGASKNCGGGGSANGSTGDQELGLDLSKKSPSLPVAASHDDTQHSESQHGSPQSASVPAANSASSFDESGVGASHSIADSSDPMEMDLSEECHHSMTESSQRKGLRHSSRKKEWIKKDNAFDRKDGGKDRDEGEGLPNGILLGPLSKSVERSLAGSYGADLPYSCKEEVENGKENSDDSGQSESESGGHTSANYVYRQEGFEPVAYGDNLYVCIPCGKGFPSSEQLNAHVETHTEEDLYIKEEGTYGGKDEAEDLSNPNQSYSAESRPFKCSVCEKSYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACEECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPT", "length": 570, "header": "tr|A0A1D5P7L2-1|A0A1D5P7L2_CHICK Isoform 1 of Hypermethylated in cancer 1 protein OS=Gallus gallus OX=9031 GN=HIC2 PE=3 SV=1 CANONICAL=A0A1D5P7L2-1" }, "locus": { "chromosome": "15", "start_pos": 263185, "end_pos": 261476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059253.1", "url": "https://www.ensembl.org/id/ENSGALT00010059253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036172.1", "url": "https://www.ensembl.org/id/ENSGALP00010036172.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416768", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SQ97-1", "protein_name": "Hypermethylated in cancer 2 protein", "gene_name": "HIC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPDMELPSHSKQLLLQLNQQRTQGFLCDVIVMVENAVFRAHKNVLAASSVYFKSLVLHDNLISLDTDMVSSAVFQQILDFIYTGRLLPGEPPAEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGSGRGGAGLGRHPRSQRLSTASVIQTRYPGLVDGRKGAHAPQELSQAKGSDDELFLGGLSQEGAHGLGRPVCPGSGEAGLGGCSTNGAGGSCEQELGLDLSKKSPPLPPATPGPSLTPDDPAQLSDSQEGSPLSTSAPPVANSASYTELGGALSEPMDLEGADDNPLCLLEGPGGPPPRKSLRHSARKKEWAKKEPAAASPFERRDVAPKGPCPGEEAEGLGDRVPNGLLAGSAAAGRPFGEPPHACKEEDENGKDGSDDSAQSGSEGGPAGAPYVYRQEGFEPVPYGDNLYVCIPCAKGFPSSEQLNAHVETHAEEELLLKEEGGAYETGSAGADEEAEDLSAPSAALAAGPRPFKCSACEKTYKDAATLRQHEKTHWLARPFPCGICGKMFTQRGTMTRHMRSHLGLKPFACGECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTAPS", "length": 594 }, "evidence": [ { "id": "A0A1D5P7L2", "url": "https://omabrowser.org/oma/group/A0A1D5P7L2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A9X7-1", "protein_name": "Hypermethylated in cancer 2 protein", "gene_name": "Hic2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSGPLALRWCPWAGHRDMGPDMELPSHSKQLLLQLNQQRAKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPGDQPSEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGPGRVGTAGMGRPTRSQRLSTASVIQARYPGLVDGRKGHPAPQELPQAKGSDDELFLGSSTQESTHGLGLGGPAAGEVGLGGCSTSTNGSSGGCEQELGLDLSKKSPPLPPTTPVPHLTPEDPAQLSDSQRESPPPTSTSALPVSNSTSYVELGATPDEPMDLEGAEENHLSLLEGQGGQPRKSLRHSARKKDWNKKEPVAGSPFDRRETGSKSSCPGEEGEAPGDRVPNGVLASSAGGGGPSAPSYGEPPYPCKEEEENGKDVSEDSGQSGSEGGSGHTGGAHYVYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSTPSSTAYAAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "length": 622 }, "evidence": [ { "id": "A0A1D5P7L2", "url": "https://omabrowser.org/oma/group/A0A1D5P7L2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96JB3-1", "protein_name": "Hypermethylated in cancer 2 protein", "gene_name": "HIC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGGTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGHASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "length": 615 }, "evidence": [ { "id": "A0A1D5P7L2", "url": "https://omabrowser.org/oma/group/A0A1D5P7L2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JLZ6-1", "protein_name": "Hypermethylated in cancer 2 protein", "gene_name": "Hic2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSGPLALRWCPWAGHRDMGPDMELPSHSKQLLLQLNQQRAKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPSEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGPGRVGTAGIGRPTRSQRLSTASVIQARFPGLVDVRKGHPAPQELPQAKGSDDELFLGTSTQESTHGLGLGGPAGGEMGLGGCSTSTNGSSGGCEQELGLDLSKKSPPLPPTTPGPHLTPEDPAQLSDSQRESPAPTSTSALPVGNSASFVELGATPEEPMDVEGAEENHLSLLEGQGGQPRKSLRHSARKKDWNKKEPVAGSPFDRRETGSKGSCPGEEGEGTGDRVPNGVLASSAGGGGPSASYGEQSFPCKEEEENGKDGSEDSGQSGSEGGSGHTGAHYVYRQEGYETVSYGDNVYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSTPSAAYTADSRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS", "length": 619 }, "evidence": [ { "id": "A0A1D5P7L2", "url": "https://omabrowser.org/oma/group/A0A1D5P7L2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7L2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 87, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5P7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7L2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 402, "end_pos": 429, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P7Q2-1", "uniprot_ac": "A0A1D5P7Q2", "uniprot_id": "A0A1D5P7Q2_CHICK", "mass": { "chemical_mass": 39019.0, "monoisotopic_mass": 39019.0 }, "refseq": { "ac": "XP_015132257", "name": "prostaglandin D2 receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132257" }, "gene_names": [ { "name": "LOC107051813", "type": "recommended", "evidence": [ { "id": "A0A1D5P7Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Q2" } ] }, { "name": "LOC107051813", "type": "synonym", 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is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. 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"PTGDR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPLFYRCHNTTSVEKGNSATMGGVLFSTGLVGNLLALGLLARSGLGSCPPRSPRPPPSVFYVLVFGLTITDLLGKCLVSPFVLSAYAQNRSLRELVPGSDSSLCQAFAFIMSFFGLASTLQLLAMALECWLSLGHPFFHRRHLTPRRGAMVAPVVGAFCLAFCALPLVGFGKFVQYCPGTWCFFQMVHEERSLSVLSYSVLYASLMLLLVLAIVLCNLSAMRNLYAMHLRLRGLLRPGSRERAEPGAGEREATPLHLEELDHLLLLALMTVLFTMCSLPLIYRAYYGAFKAVPEQNGTTEETEDLRALRFLSVISIVDPWIFIIFRTSVFRMFFRKIFIRPLIYRNWHSNSCQTNMESSL", "length": 361 }, "evidence": [ { "id": "A0A1D5P7Q2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Q2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35932-1", "protein_name": "Prostaglandin D2 receptor-like", "gene_name": "Ptgdrl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZJ23/entry", "sequence": { "sequence": "MFQFEKQAVAENMMSAEIYYQQVVTSSWGSLNTSDEISGIHTVSTRRRGRMSQLIRSHIPPRTERMAVDQDWSSVYPTAAAFKPASVPLPIRMGYPVKGGVPPPKEGNLELIKIPNFLHLTPPAIKKHCAALRDFCTEWPSALDGDEKCEQHFPVEIETVDYVSAGTSIRNPKARIVTLRVKLSNLNLDDHAKKKLIKLVGKRYCKDTDVLTIITDRCPLRRQNYDYGIHLLTVLYHESWKTEAWESEKTEEDMEEYIWENSSSQKNALDTLLQIKATENVSNVTKEELLASEVVRNYRNSVIALKNEGETESNMSQYKESVKKLLNIQALP", "length": 332, "header": "tr|A0A8V0ZJ23-1|A0A8V0ZJ23_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein S35 OS=Gallus gallus OX=9031 GN=MRPS35 PE=1 SV=1 CANONICAL=A0A1D5P7Q3-1" }, "locus": { "chromosome": "1", "start_pos": 72750882, "end_pos": 72719476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055137.1", "url": "https://www.ensembl.org/id/ENSGALT00010055137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033352.1", "url": "https://www.ensembl.org/id/ENSGALP00010033352.1" } ] } }, { "isoform_ac": "A0A8V0ZPD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPD3/entry", "sequence": { "sequence": "MQLLFQRWRQQVAAYFSTPAASSREAQQREVSTRRRGRMSQLIRSHIPPRTERMAVDQDWSSVYPTAAAFKPASVPLPIRMGYPVKGGVPPPKEGNLELIKIPNFLHLTPPAIKKHCAALRDFCTEWPSALDGDEKCEQHFPVEIETVDYVSAGTSIRNPKARIVTLRVKLSNLNLDDHAKKKLIKLVGKRYCKDTDVLTIITDRCPLRRQNYDYGIHLLTVLYHESWKTEAWESEKTEEDMEEYIWENSSSQKNALDTLLQIKATENVSNVTKEELLASEVVRNYRNSVIALKNEGETESNMSQYKESVKKLLNIQALP", "length": 320, "header": "tr|A0A8V0ZPD3-1|A0A8V0ZPD3_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein S35 OS=Gallus gallus OX=9031 GN=MRPS35 PE=1 SV=1 CANONICAL=A0A1D5P7Q3-1" }, "locus": { "chromosome": "1", "start_pos": 72750882, "end_pos": 72729691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055123.1", "url": "https://www.ensembl.org/id/ENSGALT00010055123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033339.1", "url": "https://www.ensembl.org/id/ENSGALP00010033339.1" } ] } } ], 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"evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7Q3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P7Q3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 389, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P7Q3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P7Q3" } ], "lectin_list": [], "domain_list": [ { 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"MLPTPFSVEDILSLEQSSAPGAPGVRRSPSVEEEPPSGQCLLSQPLQADQQQTDPCHHPKQPQRRKPRVLFSQTQVLELERRFKQQKYLSALEREHLANVLQLTSTQVKIWFQNRRYKCKRQRQDRSLEMATYPLPPRRVAVPVLVRDGKPCFEGSQPHLAPYGITVSPYSYSTYYSAYGVSYGVGYTGVLTP", "length": 193, "header": "tr|A0A1D5P7T8-1|A0A1D5P7T8_CHICK Isoform 1 of NK2 homeobox 6 OS=Gallus gallus OX=9031 GN=NKX2-6 PE=3 SV=1 CANONICAL=A0A1D5P7T8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8/entry", "sequence": { "sequence": "MLPTPFSVEDILSLEQSSAPGAPGVRRSPSVEEEPPSGQCLLSQPLQADQQQTDPCHHPKQPQRRKPRVLFSQTQVLELERRFKQQKYLSALEREHLANVLQLTSTQVKIWFQNRRYKCKRQRQDRSLEMATYPLPPRRVAVPVLVRDGKPCFEGSQPHLAPYGITVSPYSYSTYYSAYGVSYGVGYTGVLTP", "length": 193, "header": "tr|A0A1D5P7T8-1|A0A1D5P7T8_CHICK Isoform 1 of NK2 homeobox 6 OS=Gallus gallus OX=9031 GN=NKX2-6 PE=3 SV=1 CANONICAL=A0A1D5P7T8-1" }, "locus": { "chromosome": "22", "start_pos": 1219274, "end_pos": 1217061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048762.1", "url": "https://www.ensembl.org/id/ENSGALT00010048762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028824.1", "url": "https://www.ensembl.org/id/ENSGALP00010028824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7T8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7T8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7T8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7T8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7T8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": 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"o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P7Y2-1", "uniprot_ac": "A0A1D5P7Y2", "uniprot_id": "A0A1D5P7Y2_CHICK", "mass": { "chemical_mass": 22537.0, "monoisotopic_mass": 22537.0 }, "refseq": { "ac": "NP_001186541", "name": "tetraspanin-13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" }, "gene_names": [ { "name": "TSPAN13", "type": "recommended", "evidence": [ { "id": "A0A1D5P7Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2" } ] }, { "name": "TM4SF13", "type": "synonym", "evidence": [ { "id": "NP_001186541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] }, { "name": "TSPAN13", "type": "synonym", "evidence": [ { "id": "NP_001186541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] }, { "name": "tetraspanin-13", "type": "synonym", "evidence": [ { "id": "NP_001186541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] } ], "protein_names": [ { "name": "Tetraspanin 13", "type": "synonym", "evidence": [ { "id": "A0A1D5P7Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2/entry#names_and_taxonomy" } ] }, { "name": "tetraspan NET-6", "type": "synonym", "evidence": [ { "id": "NP_001186541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] }, { "name": "tetraspanin-13", "type": "synonym", "evidence": [ { "id": "NP_001186541", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01120158.1, BX934713.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000036.1. On Dec 11, 2010 this sequence version replaced XP_418697.2. Sequence Note: This RefSeq record was created from transcripts from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186541", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSPAN13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2", "locus": { "chromosome": "2", "start_pos": 28468138, "end_pos": 28450018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004367", "url": "https://www.ensembl.org/id/ENSGALG00010004367" } ] } } ], "crossref": [ { "id": "A0A1D5P7Y2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P7Y2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027240", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027240", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420595", "url": "https://www.ncbi.nlm.nih.gov/gene/420595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420595", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPPCAPI", "url": "https://omabrowser.org/oma/group/CPPCAPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7Y2", "url": "https://www.orthodb.org/?gene=A0A1D5P7Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPC9", "url": "https://www.orthodb.org/?gene=A0A1D5PPC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186541", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186541", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPC9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSFRVVGVAIAVGIFLFFIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNKEQQSQLLEVGWNNTKSARTDLERNLNCCGFRFFDPNETCSSDCFRSHQCQPCAPIIEEYSGMVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 203, "header": "tr|A0A1D5P7Y2-1|A0A1D5P7Y2_CHICK Isoform 1 of Tetraspanin 13 OS=Gallus gallus OX=9031 GN=TSPAN13 PE=1 SV=2 CANONICAL=A0A1D5P7Y2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2/entry", "sequence": { "sequence": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSFRVVGVAIAVGIFLFFIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNKEQQSQLLEVGWNNTKSARTDLERNLNCCGFRFFDPNETCSSDCFRSHQCQPCAPIIEEYSGMVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 203, "header": "tr|A0A1D5P7Y2-1|A0A1D5P7Y2_CHICK Isoform 1 of Tetraspanin 13 OS=Gallus gallus OX=9031 GN=TSPAN13 PE=1 SV=2 CANONICAL=A0A1D5P7Y2-1" }, "locus": { "chromosome": "2", "start_pos": 28465740, "end_pos": 28450057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010211.1", "url": "https://www.ensembl.org/id/ENSGALT00010010211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005970.1", "url": "https://www.ensembl.org/id/ENSGALP00010005970.1" } ] } }, { "isoform_ac": "A0A1D5PPC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPC9/entry", "sequence": { "sequence": "MPAFFWLVSLLLIGIAAWGIGFGLISSFRVVGVAIAVGIFLFFIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNKEQQSQLLEVGWNNTKSARTDLERNLNCCGFRFFDPNETCSSDCFRSHQCQPCAPIIEEYSGMVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 188, "header": "tr|A0A1D5PPC9-1|A0A1D5PPC9_CHICK Computationally mapped isoform of Tetraspanin 13 OS=Gallus gallus OX=9031 GN=TSPAN13 PE=1 SV=1 CANONICAL=A0A1D5P7Y2-1" }, "locus": { "chromosome": "2", "start_pos": 28465740, "end_pos": 28450478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010201.1", "url": "https://www.ensembl.org/id/ENSGALT00010010201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005962.1", "url": "https://www.ensembl.org/id/ENSGALP00010005962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420595", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SEI8-1", "protein_name": "Tetraspanin 13", "gene_name": "TSPAN13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIFQFSVSCACLALNQGQQSQLLEVGWNNTASARNDIQRNLNCCGFRRLNPNDTCLASCMKSRHSCSPCAPIIGKYAGEVLQFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 204 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95857-1", "protein_name": "Tetraspanin-13", "gene_name": "TSPAN13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQGQLLEVGWNNTASARNDIQRNLNCCGFRSVNPNDTCLASCVKSDHSCSPCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 204 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBV0-1", "protein_name": "Tetraspanin-13", "gene_name": "TSPAN13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVCGGFACSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNQEQQAQLLEVGWNNTASARDDIQRNLNCCGFRSFNPNDTCLASCVKSSHPCSPCAPIIGRYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 204 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FVL6-1", "protein_name": "Tetraspanin-13", "gene_name": "Tspan13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCGGFSCSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFRNYNPNDTCPASCAKSNQKCSSCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 204 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D8C2-1", "protein_name": "Tetraspanin-13", "gene_name": "Tspan13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVCGGFSCSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFRSYNPNDTCPASCAKSTQKCSSCAPIIGEYAGEVLRFVGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL", "length": 204 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VB99-1", "protein_name": "Tetraspanin 97E, isoform A", "gene_name": "Tsp97E", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAGAVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCGFNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSFTEVLAVFLARRYRNQHDPCYLPARAVFPHDYLY", "length": 228 }, "evidence": [ { "id": "A0A1D5P7Y2", "url": "https://omabrowser.org/oma/group/A0A1D5P7Y2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7Y2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P7Y2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 203, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P7Y2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P7Y2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P838-1", "uniprot_ac": "A0A1D5P838", "uniprot_id": "A0A1D5P838_CHICK", "mass": { "chemical_mass": 64435.0, "monoisotopic_mass": 64435.0 }, "refseq": { "ac": "NP_001290393", "name": "protein CBFA2T1 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" }, "gene_names": [ { "name": "RUNX1T1", "type": "recommended", "evidence": [ { "id": "A0A1D5P838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ] }, { "name": "CBFA2T1", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "MTG8", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "RUNX1T1", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] } ], "protein_names": [ { "name": "MTG8/ETOb", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "RUNX1 translocation partner 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838/entry#names_and_taxonomy" } ] }, { "name": "expressed during postmitotic spinal neurons, most likely in motorneurons", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "protein CBFA2T1 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "protein CBFA2T1", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "runt-related transcription factor 1", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "name": "translocated to, 1 (cyclin D-related)", "type": "synonym", "evidence": [ { "id": "NP_001290393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY714073.1, SRR13267655.79759.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_001290393.1. Transcript Variant: This variant (2) uses an alternate 5' UTR and 5' coding region, compared to variant 1. This variant encodes an isoform (2) with a shorter and distinct N-terminus, compared to isoform 1.", "evidence": [ { "database": "RefSeq", "id": "NP_001290393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ] }, { "annotation": "Both wild type MTGs and chimeric AML1-MTG proteins display in vitro RNA-binding properties Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001290393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" }, { "database": "PubMed", "id": "18950503", "url": "https://glygen.org/publication/PubMed/18950503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUNX1T1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838", "locus": { "chromosome": "2", "start_pos": 124637531, "end_pos": 124747175, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011273", "url": "https://www.ensembl.org/id/ENSGALG00010011273" } ] } } ], "crossref": [ { "id": "A0A1D5P838", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P838", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033091", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033091", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395503", "url": "https://www.ncbi.nlm.nih.gov/gene/395503", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395503", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395503", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDMIATE", "url": "https://omabrowser.org/oma/group/HDMIATE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P838", "url": "https://www.orthodb.org/?gene=A0A1D5P838", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBA3", "url": "https://www.orthodb.org/?gene=A0A1D5PBA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3Z9", "url": "https://www.orthodb.org/?gene=A0A8V0Y3Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8P7", "url": "https://www.orthodb.org/?gene=A0A8V0Y8P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8Q9", "url": "https://www.orthodb.org/?gene=A0A8V0Y8Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA91", "url": "https://www.orthodb.org/?gene=A0A8V0YA91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCF2", "url": "https://www.orthodb.org/?gene=A0A8V0YCF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH50", "url": "https://www.orthodb.org/?gene=A0A8V0YH50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001290393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P838-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577, "header": "tr|A0A1D5P838-1|A0A1D5P838_CHICK Isoform 1 of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P838-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838/entry", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577, "header": "tr|A0A1D5P838-1|A0A1D5P838_CHICK Isoform 1 of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124713461, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026935.1", "url": "https://www.ensembl.org/id/ENSGALT00010026935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015340.1", "url": "https://www.ensembl.org/id/ENSGALP00010015340.1" } ] } }, { "isoform_ac": "A0A1D5PBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNLEFCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 604, "header": "tr|A0A1D5PBA3-1|A0A1D5PBA3_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124728318, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026947.1", "url": "https://www.ensembl.org/id/ENSGALT00010026947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015347.1", "url": "https://www.ensembl.org/id/ENSGALP00010015347.1" } ] } }, { "isoform_ac": "A0A8V0Y3Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3Z9/entry", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNLEFCQVTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 558, "header": "tr|A0A8V0Y3Z9-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124728318, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026945.1", "url": "https://www.ensembl.org/id/ENSGALT00010026945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015346.1", "url": "https://www.ensembl.org/id/ENSGALP00010015346.1" } ] } }, { "isoform_ac": "A0A8V0Y8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P7/entry", "sequence": { "sequence": "LPKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 573, "header": "tr|A0A8V0Y8P7-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124687278, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026922.1", "url": "https://www.ensembl.org/id/ENSGALT00010026922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015335.1", "url": "https://www.ensembl.org/id/ENSGALP00010015335.1" } ] } }, { "isoform_ac": "A0A8V0Y8Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q9/entry", "sequence": { "sequence": "VTDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577, "header": "tr|A0A8V0Y8Q9-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124687202, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026957.1", "url": "https://www.ensembl.org/id/ENSGALT00010026957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015350.1", "url": "https://www.ensembl.org/id/ENSGALP00010015350.1" } ] } }, { "isoform_ac": "A0A8V0YA91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA91/entry", "sequence": { "sequence": "MVGISGPLQLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 538, "header": "tr|A0A8V0YA91-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124747020, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026955.1", "url": "https://www.ensembl.org/id/ENSGALT00010026955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015348.1", "url": "https://www.ensembl.org/id/ENSGALP00010015348.1" } ] } }, { "isoform_ac": "A0A8V0YCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF2/entry", "sequence": { "sequence": "MPVTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 531, "header": "tr|A0A8V0YCF2-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124713461, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026929.1", "url": "https://www.ensembl.org/id/ENSGALT00010026929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015339.1", "url": "https://www.ensembl.org/id/ENSGALP00010015339.1" } ] } }, { "isoform_ac": "A0A8V0YH50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH50/entry", "sequence": { "sequence": "MPDSPVDVKTQSRLTPPTMPPPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 533, "header": "tr|A0A8V0YH50-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5P838-1" }, "locus": { "chromosome": "2", "start_pos": 124687172, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026940.1", "url": "https://www.ensembl.org/id/ENSGALT00010026940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015342.1", "url": "https://www.ensembl.org/id/ENSGALP00010015342.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 544, "start_aa": "Thr", "end_pos": 544, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr544", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Novel RNA-binding properties of the MTG chromatin regulatory proteins.", "journal": "BMC molecular biology", "date": "2008-10-24", "authors": "Rossetti Stefano, van Unen Leontine, Sacchi Nicoletta, Hoogeveen Andre T", "evidence": [ { "database": "RefSeq", "id": "NP_001290393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290393" } ], "reference": [ { "type": "PubMed", "id": "18950503", "url": "https://glygen.org/publication/PubMed/18950503" } ] } ], "pathway": [ { "id": "gga:395503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395503", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0G0-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "Runx1t1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTKRRCGGRAAGRLARSPPEGNLRGRAGGGGAGRGVGAAPQRSRADKSQGSEDVTCYRELLLAARGNLHLKITEGEGEDLPFVVLGEEEAAALASLLSPNTSAIQTGTRGDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSGSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGETPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 686 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A4X1U9K3-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "RUNX1T1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AB32T784-1", "protein_name": "Protein CBFA2T1 isoform X1", "gene_name": "runx1t1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGISTSFQSPPPPGTIWEMLLQSNERGFMRQKWLGDVCRLGMVYAGLTVSSDDRTEKRSTMPDSPADVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTALTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELVHCARLAKQNPAQYLAQHEQLLLDTSTTSPVDSSELLMDVNENGKRRTPDRTKENGFEREPLHPEHPNKRPCTISPGQRFSPSNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRELRDRPRPLGMHGSSTRQEEVIDHRLTDREWAEEWKHLDHVRKLLNCIMDMVEKTRRSLTVLRRCQETDREELNYWIRRYSDAEDLKKTSSTSTSQSRQQSPASQEGNALEVHRELLHRPVSGYVPEEIWKKAEEAVNEVKRQAMSELQKAVSEAERKAHEMISTERAKMERTVAEARRQAAEDALSVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHVCGQTLQAQQQGETPATVSSSATPSSGAGSPADTPSAAATPRSATPGTPSTVENTPR", "length": 635 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N0Y4-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "RUNX1T1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGSSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 576 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q06455-1", "protein_name": "Protein CBFA2T1", "gene_name": "RUNX1T1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNFEYCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 604 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61909-1", "protein_name": "Protein CBFA2T1", "gene_name": "Runx1t1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGDTPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577 }, "evidence": [ { "id": "A0A1D5P838", "url": "https://omabrowser.org/oma/group/A0A1D5P838/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P838" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 266, 544, 568 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P864-1", "uniprot_ac": "A0A1D5P864", "uniprot_id": "A0A1D5P864_CHICK", "mass": { "chemical_mass": 36622.0, "monoisotopic_mass": 36622.0 }, "refseq": { "ac": "XP_419207", "name": "transmembrane protein 68", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419207" }, "gene_names": [ { "name": "LOC421125", "type": "recommended", "evidence": [ { "id": "A0A1D5P864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864" } ] }, { "name": "LOC421125", "type": "synonym", "evidence": [ { "id": "XP_419207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419207" } ] } ], "protein_names": [ { "name": "Phospholipid/glycerol acyltransferase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 68", "type": "synonym", "evidence": [ { "id": "XP_419207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419207" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P864", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC421125", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864", "locus": {} } ], "crossref": [ { "id": "A0A1D5P864", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P864", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030767", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421125", "url": "https://www.ncbi.nlm.nih.gov/gene/421125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421125", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRTYIGK", "url": "https://omabrowser.org/oma/group/FRTYIGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P864", "url": "https://www.orthodb.org/?gene=A0A1D5P864", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P864", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P864-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTYLSYFACMLEEWTAVEYLKKYFFHMVIISVTISAILVFFIVPLTILFFIYLTNVLLIIYQRNGEVKADPLSDVWDSARKTVASFWDIYARIWHGYELHGVENLPEGPGIVVYYHGAIPIDYLYFLSRLFLWKKRLCLSVADHFVFRLPGLKLLLEVTGVMPGTREECLSALKNGHLVSISPGGVREALFSDESYQLMWGNRKGFAQVALDAKVPIIPMYTQNVREGYRMFKERRFFRQLYETTRLPFTPPYGGLPVKFRTYIGEPIPYDPNITTDELVEKTKTAVQALIKKHQTIPGSIWKALLDRFDKHCKSD", "length": 316, "header": "tr|A0A1D5P864-1|A0A1D5P864_CHICK Isoform 1 of Phospholipid/glycerol acyltransferase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC421125 PE=4 SV=1 CANONICAL=A0A1D5P864-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P864-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P864/entry", "sequence": { "sequence": "MTYLSYFACMLEEWTAVEYLKKYFFHMVIISVTISAILVFFIVPLTILFFIYLTNVLLIIYQRNGEVKADPLSDVWDSARKTVASFWDIYARIWHGYELHGVENLPEGPGIVVYYHGAIPIDYLYFLSRLFLWKKRLCLSVADHFVFRLPGLKLLLEVTGVMPGTREECLSALKNGHLVSISPGGVREALFSDESYQLMWGNRKGFAQVALDAKVPIIPMYTQNVREGYRMFKERRFFRQLYETTRLPFTPPYGGLPVKFRTYIGEPIPYDPNITTDELVEKTKTAVQALIKKHQTIPGSIWKALLDRFDKHCKSD", "length": 316, "header": "tr|A0A1D5P864-1|A0A1D5P864_CHICK Isoform 1 of Phospholipid/glycerol acyltransferase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC421125 PE=4 SV=1 CANONICAL=A0A1D5P864-1" }, "locus": { "chromosome": "2", "start_pos": 110745015, "end_pos": 110731933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010660.1", "url": "https://www.ensembl.org/id/ENSGALT00010010660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006172.1", "url": "https://www.ensembl.org/id/ENSGALP00010006172.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421125", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015150794.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150794" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P876", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P876" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBALD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P876", "locus": { "chromosome": "18", "start_pos": 5095064, "end_pos": 5099999, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029449", "url": "https://www.ensembl.org/id/ENSGALG00010029449" } ] } } ], "crossref": [ { "id": "A0A1D5P876", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P876", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P882-1", "uniprot_ac": "A0A1D5P882", "uniprot_id": "A0A1D5P882_CHICK", "mass": { "chemical_mass": 62649.0, "monoisotopic_mass": 62649.0 }, "refseq": { "ac": "XP_015132463", "name": "arf-GAP domain and FG repeat-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132463" }, "gene_names": [ { "name": "AGFG1", "type": "recommended", "evidence": [ { "id": "A0A1D5P882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ] }, { "name": "AGFG1", "type": "synonym", "evidence": [ { "id": "XP_015132463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132463" } ] } ], "protein_names": [ { "name": "Arf-GAP domain and FG repeat-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5P882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882/entry#names_and_taxonomy" } ] }, { "name": "Nucleoporin-like protein RIP", "type": "synonym", "evidence": [ { "id": "A0A1D5P882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP domain and FG repeat-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015132463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132463" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132463" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AGFG1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882", "locus": { "chromosome": "9", "start_pos": 9177776, "end_pos": 9141749, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023830", "url": "https://www.ensembl.org/id/ENSGALG00010023830" } ] } } ], "crossref": [ { "id": "A0A1D5P882", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P882", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003052", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08857", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08857", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424793", "url": "https://www.ncbi.nlm.nih.gov/gene/424793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424793", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SDCKRNK", "url": "https://omabrowser.org/oma/group/SDCKRNK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P882", "url": "https://www.orthodb.org/?gene=A0A1D5P882", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPA9", "url": "https://www.orthodb.org/?gene=A0A8V0ZPA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZUI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY62", "url": "https://www.orthodb.org/?gene=A0A8V0ZY62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46134:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46134:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015132463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P882-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAKRKQEEKHLKLLREMSSLPPNRKCFDCDQRGPTYTDMTVGSFVCTSCSGILRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTAQNSANAGFANFDAFGQSSGSSNFGGFPTASQSSFQPQNTAFRTLSSSCSFGEFTSAFPLQAVHSGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATPSTNPFVAAPVAPVAPSTNPFQTNSRGATGLSGAMHSHIFPHAHFAATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 604, "header": "tr|A0A1D5P882-1|A0A1D5P882_CHICK Isoform 1 of Arf-GAP domain and FG repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P882-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882/entry", "sequence": { "sequence": "MAASAKRKQEEKHLKLLREMSSLPPNRKCFDCDQRGPTYTDMTVGSFVCTSCSGILRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTAQNSANAGFANFDAFGQSSGSSNFGGFPTASQSSFQPQNTAFRTLSSSCSFGEFTSAFPLQAVHSGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATPSTNPFVAAPVAPVAPSTNPFQTNSRGATGLSGAMHSHIFPHAHFAATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 604, "header": "tr|A0A1D5P882-1|A0A1D5P882_CHICK Isoform 1 of Arf-GAP domain and FG repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "locus": { "chromosome": "9", "start_pos": 9176642, "end_pos": 9141916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058086.1", "url": "https://www.ensembl.org/id/ENSGALT00010058086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035264.1", "url": "https://www.ensembl.org/id/ENSGALP00010035264.1" } ] } }, { "isoform_ac": "A0A8V0ZPA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA9/entry", "sequence": { "sequence": "MQGSARRTLLEDRGRVAQRRAFMTRKIRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTAQNSANAGFANFDAFGQSSGSSNFGGFPTASQSSFQPQNTGGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATPSTNPFVAAPVAPVAPSTNPFQTNSRGATAATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 535, "header": "tr|A0A8V0ZPA9-1|A0A8V0ZPA9_CHICK Computationally mapped isoform of ArfGAP with FG repeats 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "locus": { "chromosome": "9", "start_pos": 9176642, "end_pos": 9142518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058079.1", "url": "https://www.ensembl.org/id/ENSGALT00010058079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035257.1", "url": "https://www.ensembl.org/id/ENSGALP00010035257.1" } ] } }, { "isoform_ac": "A0A8V0ZPC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC1/entry", "sequence": { "sequence": "MAASAKRKQEEKHLKLLREMSSLPPNRKCFDCDQRGPTYTDMTVGSFVCTSCSGILRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTAQNSANAGFANFDAFGQSSGSSNFGGFPTASQSSFQPQNTAFRTLSSSCSFGEFTSAFPLQAVHSGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATPSTNPFVAAPVAPVAPSTNPFQTNSRGATAATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 588, "header": "tr|A0A8V0ZPC1-1|A0A8V0ZPC1_CHICK Computationally mapped isoform of Arf-GAP domain and FG repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "locus": { "chromosome": "9", "start_pos": 9176642, "end_pos": 9141916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058089.1", "url": "https://www.ensembl.org/id/ENSGALT00010058089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035267.1", "url": "https://www.ensembl.org/id/ENSGALP00010035267.1" } ] } }, { "isoform_ac": "A0A8V0ZUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUI5/entry", "sequence": { "sequence": "MLQCWITRRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTGGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATPSTNPFVAAPVAPVAPSTNPFQTNSRGATGLSGAMHSHIFPHAHFAATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 492, "header": "tr|A0A8V0ZUI5-1|A0A1D5P882_CHICK Computationally mapped isoform of Arf-GAP domain and FG repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "locus": { "chromosome": "9", "start_pos": 9176642, "end_pos": 9142649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058075.1", "url": "https://www.ensembl.org/id/ENSGALT00010058075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035253.1", "url": "https://www.ensembl.org/id/ENSGALP00010035253.1" } ] } }, { "isoform_ac": "A0A8V0ZY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY62/entry", "sequence": { "sequence": "MAASAKRKQEEKHLKLLREMSSLPPNRKCFDCDQRGPTYTDMTVGSFVCTSCSGILRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGEAAPALHLNKGTPSQSPVVGRSQGQQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHTAQNSANAGFANFDAFGQSSGSSNFGGFPTASQSSFQPQNTGGSAGSVNANFAHFDNFPKSSSADFGAFNASQSNATVTGASKAAVNKPGLQSADKYAALANLDNIFSAGQGGSEQGSGFSTVVSASAGPALSAPNQSSASSDKYAALAELDSVFSSTATSSNAYTSTSNVSSNAFGTVPVAATSQTQPASSSVPASFGATFGTASMSMPAGFGTPASYSLPTSFSGNFQQPTFPTQAAFPQQTAFAQQPNGAGFAAFGQAKPVVTPFGQVAAVGVSSNPFMAGAPTGQFPAGNSSTNPFL", "length": 532, "header": "tr|A0A8V0ZY62-1|A0A1D5P882_CHICK Computationally mapped isoform of Arf-GAP domain and FG repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=AGFG1 PE=1 SV=1 CANONICAL=A0A1D5P882-1" }, "locus": { "chromosome": "9", "start_pos": 9176642, "end_pos": 9141916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058082.1", "url": "https://www.ensembl.org/id/ENSGALT00010058082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035260.1", "url": "https://www.ensembl.org/id/ENSGALP00010035260.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424793", "resource": "KEGG Pathway" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287APA8-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPALHLNKGTPTQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSSFQPQTTGGSAGSVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSANKAGVQTTDKYAALANLDNIFSAGQGGDQGSGFGATGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVGASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPAGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL", "length": 562 }, "evidence": [ { "id": "A0A1D5P882", "url": "https://omabrowser.org/oma/group/A0A1D5P882/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL", "length": 562 }, "evidence": [ { "id": "A0A1D5P882", "url": "https://omabrowser.org/oma/group/A0A1D5P882/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2K6-4", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "Agfg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSSFQPQTTGGSAGSVNANFAHFDNFPKSSSADFGTFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSSNAYTPTSNASSSVFGTVPVGASAQTQPASSGPAPFGATPSTNPFVAATGPSAASSTNPFQTNARGATAATFGTASMSMPAGFGTPAQYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFATFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQLPTGSSSTNPFL", "length": 561 }, "evidence": [ { "id": "A0A1D5P882", "url": "https://omabrowser.org/oma/group/A0A1D5P882/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "spermatid nucleus differentiation", "id": "GO:0007289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007289", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P882", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P882-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 604, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P882-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P882" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P882" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 135, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 456 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 325, "end_pos": 327 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 597, "end_pos": 599 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P885-1", "uniprot_ac": "A0A1D5P885", "uniprot_id": "A0A1D5P885_CHICK", "mass": { "chemical_mass": 55111.0, "monoisotopic_mass": 55111.0 }, "refseq": { "ac": "XP_003642578", "name": "intermediate filament family orphan 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642578" }, "gene_names": [ { "name": "IFFO2", "type": "recommended", "evidence": [ { "id": "A0A1D5P885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885" } ] }, { "name": "IFFO2", "type": "synonym", "evidence": [ { "id": "XP_003642578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642578" } ] } ], "protein_names": [ { "name": "Intermediate filament family orphan 2", "type": "synonym", "evidence": [ { "id": "A0A1D5P885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885/entry#names_and_taxonomy" } ] }, { "name": "intermediate filament family orphan 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642578" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P885", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFFO2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885", "locus": { "chromosome": "21", "start_pos": 4555883, "end_pos": 4583259, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020489", "url": "https://www.ensembl.org/id/ENSGALG00010020489" } ] } } ], "crossref": [ { "id": "A0A1D5P885", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P885", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029831", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029831", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419468", "url": "https://www.ncbi.nlm.nih.gov/gene/419468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419468", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419468", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGAAACC", "url": "https://omabrowser.org/oma/group/KGAAACC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P885", "url": "https://www.orthodb.org/?gene=A0A1D5P885", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14516", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14516", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14516:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14516:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P885", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P885-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSLLFGEMARAFSPGVAAAGSGSPGAAGGAAGGPPVTAALRNDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLAAQQCERDRRLRYKTFSRDQAVQTDGGLPLPGVALSAGPAPGLAPSHYSRLPGTIWSYTQVRRTGGGGLETVQGPGVSWIHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRKWEEELTRRMSLESMVETLREEAQEAEALQEELNEKIERLKAELVVFKGLMSDPMTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQVASKKKERKLASDDDLSEQDADNSRFSDDEVSCSLNITDEMKRMFNQLRETFDFDDDCDSLTWEENEETLLLWEDFTNCNPSIDLQGEEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGNTDEIQDELDRDADVEPMVS", "length": 491, "header": "tr|A0A1D5P885-1|A0A1D5P885_CHICK Isoform 1 of Intermediate filament family orphan 2 OS=Gallus gallus OX=9031 GN=IFFO2 PE=4 SV=1 CANONICAL=A0A1D5P885-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P885-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P885/entry", "sequence": { "sequence": "MNSLLFGEMARAFSPGVAAAGSGSPGAAGGAAGGPPVTAALRNDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLAAQQCERDRRLRYKTFSRDQAVQTDGGLPLPGVALSAGPAPGLAPSHYSRLPGTIWSYTQVRRTGGGGLETVQGPGVSWIHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRKWEEELTRRMSLESMVETLREEAQEAEALQEELNEKIERLKAELVVFKGLMSDPMTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQVASKKKERKLASDDDLSEQDADNSRFSDDEVSCSLNITDEMKRMFNQLRETFDFDDDCDSLTWEENEETLLLWEDFTNCNPSIDLQGEEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGNTDEIQDELDRDADVEPMVS", "length": 491, "header": "tr|A0A1D5P885-1|A0A1D5P885_CHICK Isoform 1 of Intermediate filament family orphan 2 OS=Gallus gallus OX=9031 GN=IFFO2 PE=4 SV=1 CANONICAL=A0A1D5P885-1" }, "locus": { "chromosome": "21", "start_pos": 4583124, "end_pos": 4556375, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049515.1", "url": "https://www.ensembl.org/id/ENSGALT00010049515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029259.1", "url": "https://www.ensembl.org/id/ENSGALP00010029259.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419468", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419468", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q7X1-1", "protein_name": "Intermediate filament family orphan 2 isoform X1", "gene_name": "iffo2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLLFGEGFLGGAVSGAPSDAVPRALRNDLGSNIHVLKTLNLRFRCFLAKVHELERRNKLLESQLKQATGQPRYPGFSFTREVAVQTDSLESRLPGTIWSFTHILRHGERVKTVQGPGVTWTHPDGVGVQIDTITPELRALYNVLAKVKRERDEYKRKWEEELSRREQMEVMVQSLQENVNQSEAIQDELNEKVERLKAELVVFKSLMSDAGGRRRNKAVENQRKILDLKQMSDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDMSKIFSPSRAPADRAVACRKKERKAVSDEESSEMDADPSSTSEEDAPFNITDEMKRMLNQLHCSDNSFVARRETFEIDDDCDSLTWEENDDTLLLWEDFTNYNVPCSALTNGNGDCSTDGHEADSSLGSLIDETESLFKTREQEYQKTIGQIEMELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRMIKGGRNSPSISSSASSDSGNTDEIQEESDKDGETDGPIS", "length": 501 }, "evidence": [ { "id": "A0A1D5P885", "url": "https://omabrowser.org/oma/group/A0A1D5P885/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LN94-1", "protein_name": "Intermediate filament family orphan 2", "gene_name": "IFFO2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNSLLFGEMALAFGCPPGGGGGSCPGGGGGGGAGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPAPGGGYGSGAAAGVNANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEAEAIQEEMNEKIERLKAELVVFKGLMSDPMTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQVVPKKKERKVASDDDISEQDGEVNRFSDDEVGSMNITDEMKRMFNQLRETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQGEQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDEFEREADVEPMVS", "length": 514 }, "evidence": [ { "id": "A0A1D5P885", "url": "https://omabrowser.org/oma/group/A0A1D5P885/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TF58-1", "protein_name": "Intermediate filament family orphan 2", "gene_name": "IFFO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSLLFGEMALAFGCPPGGGGGGCPGGGGGGGGAGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPAPGGGHGLSSGAAAGANANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEADAIQEEMNEKIERLKAELVVFKGLMSDPMTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQVVPKKKERKVASDDDISEQDGEVNRFSDDEVGSMNITDEMKRMFNQLRETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQGEQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDEFEREADVEPMVS", "length": 517 }, "evidence": [ { "id": "A0A1D5P885", "url": "https://omabrowser.org/oma/group/A0A1D5P885/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P885-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P885-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P885" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P8E9-1", "uniprot_ac": "A0A1D5P8E9", "uniprot_id": "A0A1D5P8E9_CHICK", "mass": { "chemical_mass": 7011.0, "monoisotopic_mass": 7011.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A1D5P8E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8E9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9", "locus": {} } ], "crossref": [ { "id": "A0A1D5P8E9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8E9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037957", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037957", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P8E9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P8E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGLETDDNTLIRVVVSCSEIDVLDIRREFLTMYGKSIYSFIKGDCSGDYRKVLLKLCGGED", "length": 62, "header": "tr|A0A1D5P8E9-1|A0A1D5P8E9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=2 CANONICAL=A0A1D5P8E9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9/entry", "sequence": { "sequence": "MEGLETDDNTLIRVVVSCSEIDVLDIRREFLTMYGKSIYSFIKGDCSGDYRKVLLKLCGGED", "length": 62, "header": "tr|A0A1D5P8E9-1|A0A1D5P8E9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=2 CANONICAL=A0A1D5P8E9-1" }, "locus": { "chromosome": "3", "start_pos": 2514465, "end_pos": 2513324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040107.1", "url": "https://www.ensembl.org/id/ENSGALT00010040107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023248.1", "url": "https://www.ensembl.org/id/ENSGALP00010023248.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8E9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8E9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P8E9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 62, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P8E9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8E9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P8F5-1", "uniprot_ac": "A0A1D5P8F5", "uniprot_id": "A0A1D5P8F5_CHICK", "mass": { "chemical_mass": 45222.0, "monoisotopic_mass": 45222.0 }, "refseq": { "ac": "XP_426020", "name": "SH3 and cysteine-rich domain-containing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426020" }, "gene_names": [ { "name": "STAC", "type": "recommended", "evidence": [ { "id": "A0A1D5P8F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ] }, { "name": "STAC", "type": "synonym", "evidence": [ { "id": "XP_426020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426020" } ] } ], "protein_names": [ { "name": "SH3 and cysteine-rich domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5P8F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5/entry#names_and_taxonomy" } ] }, { "name": "SH3 and cysteine-rich domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426020" } ] }, { "name": "Src homology 3 and cysteine-rich domain-containing protein", "type": "synonym", "evidence": [ { "id": "A0A1D5P8F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_426020.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426020" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STAC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5", "locus": { "chromosome": "2", "start_pos": 45747763, "end_pos": 45674291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018391", "url": "https://www.ensembl.org/id/ENSGALG00010018391" } ] } } ], "crossref": [ { "id": "A0A1D5P8F5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039092", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039092", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11833", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11833", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20880", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20880", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428460", "url": "https://www.ncbi.nlm.nih.gov/gene/428460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428460", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428460", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYRCVRT", "url": "https://omabrowser.org/oma/group/IYRCVRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P8F5", "url": "https://www.orthodb.org/?gene=A0A1D5P8F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z676", "url": "https://www.orthodb.org/?gene=A0A8V0Z676", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15135", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15135", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15135:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15135:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426020", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P8F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z676", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z676", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z676-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z676-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPPSSMTEVSVDSVEKENEVESTEQPPSPASTTSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSDVKLQVDLMPEVSTSTGQLPSSESQASSPTRTQQLSENNKAHIFQEHIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCADSIGQQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQKTKKGSSGSGSDSPNRNSTADLAEVPEEADSSLDISRKRSNSVFTYSENGTEHFGEEPKSIHSPGPFYKNTLQMNTYVALYKFVPQENEDLEMRPGDMITLLEDSNEDWWKGKIDDRTGFFPANFVQRVQHDEKIYRCIRTFIGCKEQGQITLKENQICVTSEKEHDGFIKVYSGKKKGFVPIDVLENI", "length": 402, "header": "tr|A0A1D5P8F5-1|A0A1D5P8F5_CHICK Isoform 1 of SH3 and cysteine-rich domain-containing protein OS=Gallus gallus OX=9031 GN=STAC PE=4 SV=1 CANONICAL=A0A1D5P8F5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5/entry", "sequence": { "sequence": "MIPPSSMTEVSVDSVEKENEVESTEQPPSPASTTSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSDVKLQVDLMPEVSTSTGQLPSSESQASSPTRTQQLSENNKAHIFQEHIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCADSIGQQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQKTKKGSSGSGSDSPNRNSTADLAEVPEEADSSLDISRKRSNSVFTYSENGTEHFGEEPKSIHSPGPFYKNTLQMNTYVALYKFVPQENEDLEMRPGDMITLLEDSNEDWWKGKIDDRTGFFPANFVQRVQHDEKIYRCIRTFIGCKEQGQITLKENQICVTSEKEHDGFIKVYSGKKKGFVPIDVLENI", "length": 402, "header": "tr|A0A1D5P8F5-1|A0A1D5P8F5_CHICK Isoform 1 of SH3 and cysteine-rich domain-containing protein OS=Gallus gallus OX=9031 GN=STAC PE=4 SV=1 CANONICAL=A0A1D5P8F5-1" }, "locus": { "chromosome": "2", "start_pos": 45744840, "end_pos": 45674488, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044413.1", "url": "https://www.ensembl.org/id/ENSGALT00010044413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026431.1", "url": "https://www.ensembl.org/id/ENSGALP00010026431.1" } ] } }, { "isoform_ac": "A0A8V0Z676-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z676/entry", "sequence": { "sequence": "MPLHKMLQKLKRSLSFKTKSLRSKSADNFFQRTNSDVKLQVDLMPEVSTSTGQLPSSESQASSPTRTQQLSENNKAHIFQEHIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCADSIGQQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQKTKKGSSGSGSDSPNRNSTADLAEVPEEADSSLDISRKRSNSVFTYSENGTEHFGEEPKSIHSPGPFYKNTLQMNTYVALYKFVPQENEDLEMRPGDMITLLEDSNEDWWKGKIDDRTGFFPANFVQRVQHDEKIYRCIRTFIGCKEQGQITLKENQICVTSEKEHDGFIKVYSGKKKGFVPIDVLENI", "length": 369, "header": "tr|A0A8V0Z676-1|A0A8V0Z676_CHICK Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein OS=Gallus gallus OX=9031 GN=STAC PE=4 SV=1 CANONICAL=A0A1D5P8F5-1" }, "locus": { "chromosome": "2", "start_pos": 45744840, "end_pos": 45679564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044412.1", "url": "https://www.ensembl.org/id/ENSGALT00010044412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026430.1", "url": "https://www.ensembl.org/id/ENSGALP00010026430.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428460", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428460", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0JNJ1-1", "protein_name": "SH3 and cysteine-rich domain-containing protein", "gene_name": "STAC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIPPSGAREDGVDGLPKETASAEQPPSPASTGSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSDVKLQADVLAGVSPGSSPLPAPGSLTCTPTRAGLYPGGGGKAHAFQEHIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCMDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKSSSGSGSDSPHRTSTSDLVEVPEEADGPGDGYDLRKRSNSVFTYPENGTDDFRDQAKNINHQGPLSKDPLQMNTYVALYKFVPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRIGFFPANFVQRVHQNEKIFRCVRTFSGCKEQGQITLKENQICVASEEEQDGFIRVLSGKKRGLVPLDVLENI", "length": 403 }, "evidence": [ { "id": "A0A1D5P8F5", "url": "https://omabrowser.org/oma/group/A0A1D5P8F5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M107-1", "protein_name": "SH3 and cysteine-rich domain-containing protein", "gene_name": "Stac", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPPSGAREDSGDGLTREATGTEQPPSPASTSSLESKLQKLKRSLSFKTKSLRSKSADNFFPRTNSDVKPQADLLAKASPGPSPIPIPGSPASMPTKAGLHPGSNSKVHAFQEHVFKKPTFCDVCNHMIVGTHAKHGLRCGACKMSIHHKCADGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYEALRFGTSLAQRTKKSSSGSGSDSPPRTSTSELVEVPEEADGPGDSSDIRPRSNSVFTYPENGTDDFRDQVKTINHQGPLSKDPLQMNTYVALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVEEHEKIYRCVRTFIGCKDQGQITLKENQICVTSEEERDGFIRVLSGKKRGLVPLDVLVDV", "length": 403 }, "evidence": [ { "id": "A0A1D5P8F5", "url": "https://omabrowser.org/oma/group/A0A1D5P8F5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97306-1", "protein_name": "SH3 and cysteine-rich domain-containing protein", "gene_name": "Stac", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPPSGAREDSGDGLTGEATGTEQPPSPASTSSLESKLQKLKRSLSFKTKSLRSKSADNFFPRTNSDVKPQADLLAKASPGPSPIAIPGSPASMPTKAGLHPGSNSKLHAFQEHVFKKPTFCDVCNHMIVGTHAKHGLRCGACKMSIHHKCADGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYEALRFGTSLAQRTKKGGSGSGSDSPPRTSTSELVDVPEEADGPGDGSDMRTRSNSVFTYPENGMDDFRDQMKTTNHQGPLSKDPLQMNTYVALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVEEHEKIYRCVRTFIGCKDQGQITLKENQICVTSEEEQDGFIRVLSGKKRGLVPLDVLVDV", "length": 403 }, "evidence": [ { "id": "A0A1D5P8F5", "url": "https://omabrowser.org/oma/group/A0A1D5P8F5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99469-1", "protein_name": "SH3 and cysteine-rich domain-containing protein", "gene_name": "STAC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI", "length": 402 }, "evidence": [ { "id": "A0A1D5P8F5", "url": "https://omabrowser.org/oma/group/A0A1D5P8F5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8F5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8F5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P8F5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P8F5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P8F5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 262, "end_pos": 264 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P8G4-1", "uniprot_ac": "A0A1D5P8G4", "uniprot_id": "A0A1D5P8G4_CHICK", "mass": { "chemical_mass": 11499.0, "monoisotopic_mass": 11499.0 }, "refseq": { "ac": "NP_001376368", "name": "serine-rich and transmembrane domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376368" }, "gene_names": [ { "name": "SERTM1", "type": "recommended", "evidence": [ { "id": "A0A1D5P8G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8G4" } ] }, { "name": "SERTM1", "type": "synonym", "evidence": [ { "id": "NP_001376368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376368" } ] } ], "protein_names": [ { "name": "Serine rich and transmembrane domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P8G4", "database": "UniProtKB", "url": 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The reference sequence was derived from JAENSK010000027.1. 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The reference sequence was derived from JAENSK010000065.1. On Mar 4, 2015 this sequence version replaced NP_990352.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990352" } ] }, { "annotation": "Collagen XII interacts with avian tenascin-X through its NC3 domain", "evidence": [ { "database": "RefSeq", "id": "NP_990352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990352" }, { "database": "PubMed", "id": "16861231", "url": "https://glygen.org/publication/PubMed/16861231" } ] }, { "annotation": "Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P8I8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8I8#function" }, { "database": "UniProtKB", "id": "ARBA00053577", "url": "https://www.uniprot.org/uniprotkb/ARBA00053577#function" }, { "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395875", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395875", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIIRYKT", "url": "https://omabrowser.org/oma/group/YIIRYKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P8I8", "url": "https://www.orthodb.org/?gene=A0A1D5P8I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RPW4", "url": "https://www.orthodb.org/?gene=A0A1L1RPW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NX22", "url": "https://www.orthodb.org/?gene=F1NX22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P8I8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P8I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX22", "url": "https://www.uniprot.org/uniprotkb/F1NX22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX22-1", "url": "https://www.uniprot.org/uniprotkb/F1NX22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEPYVPESGPYQPEGEPFIVPMESERREDEYEDYGVEMHSPEYPEHMRWKRSLSRKAKRKP", "length": 3122, "header": "tr|A0A1L1RPW4-1|A0A1L1RPW4_CHICK Isoform 1 of Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=1 CANONICAL=A0A1L1RPW4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8I8/entry", "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPGFG", "length": 3065, "header": "tr|A0A1D5P8I8-1|A0A1L1RPW4_CHICK Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=2 CANONICAL=A0A1L1RPW4-1" }, "locus": { "chromosome": "3", "start_pos": 80597521, "end_pos": 80501730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009589.1", "url": "https://www.ensembl.org/id/ENSGALT00010009589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005635.1", "url": "https://www.ensembl.org/id/ENSGALP00010005635.1" } ] } }, { "isoform_ac": "A0A1L1RPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4/entry", "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEPYVPESGPYQPEGEPFIVPMESERREDEYEDYGVEMHSPEYPEHMRWKRSLSRKAKRKP", "length": 3122, "header": "tr|A0A1L1RPW4-1|A0A1L1RPW4_CHICK Isoform 1 of Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=1 CANONICAL=A0A1L1RPW4-1" }, "locus": { "chromosome": "3", "start_pos": 80598946, "end_pos": 80501730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009597.1", "url": "https://www.ensembl.org/id/ENSGALT00010009597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005636.1", "url": "https://www.ensembl.org/id/ENSGALP00010005636.1" } ] } }, { "isoform_ac": "A0A8V0XG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG00/entry", "sequence": { "sequence": "LRRVLCSLINPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSVSWLISYHAFGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEPYVPESGPYQPEGEPFIVPMESERREDEYEDYGVEMHSPEYPEHMRWKRSLSRKAKRKP", "length": 3059, "header": "tr|A0A8V0XG00-1|A0A1L1RPW4_CHICK Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=1 CANONICAL=A0A1L1RPW4-1" }, "locus": { "chromosome": "3", "start_pos": 80598946, "end_pos": 80509399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009577.1", "url": "https://www.ensembl.org/id/ENSGALT00010009577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005629.1", "url": "https://www.ensembl.org/id/ENSGALP00010005629.1" } ] } }, { "isoform_ac": "F1NX22-1", "url": "https://www.uniprot.org/uniprotkb/F1NX22/entry", "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEQG", "length": 3065, "header": "tr|F1NX22-1|A0A1L1RPW4_CHICK Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Gallus gallus OX=9031 GN=COL12A1 PE=1 SV=4 CANONICAL=A0A1L1RPW4-1" }, "locus": { "chromosome": "3", "start_pos": 80596766, "end_pos": 80501730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009585.1", "url": "https://www.ensembl.org/id/ENSGALT00010009585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005631.1", "url": "https://www.ensembl.org/id/ENSGALP00010005631.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2301, "start_aa": "Thr", "end_pos": 2301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2301", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2305, "start_aa": "Thr", "end_pos": 2305, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2305", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2827, "start_aa": "Thr", "end_pos": 2827, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2827", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2852, "start_aa": "Thr", "end_pos": 2852, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2852", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2887, "start_aa": "Thr", "end_pos": 2887, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2887", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Collagen XII interacts with avian tenascin-X through its NC3 domain.", "journal": "The Journal of biological chemistry", "date": "2006-09-15", "authors": "Veit Guido, Hansen Uwe, Keene Douglas R, Bruckner Peter, Chiquet-Ehrismann Ruth, Chiquet Matthias, Koch Manuel", "evidence": [ { "database": "RefSeq", "id": "NP_990352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990352" } ], "reference": [ { "type": "PubMed", "id": "16861231", "url": "https://glygen.org/publication/PubMed/16861231" } ] } ], "pathway": [ { "id": "gga:395875", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395875", "resource": "KEGG Pathway" }, { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N401-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRIRLPPALAALGAALLLSSIEAEVEPPSDLNFKIIDENTVHMSWAIPPDPIVGFKITVDPTTDGPTKEFTLSASTTETLLTELIPEIEYVVTITSYDEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQQEELLAAIKKIPYKGGNTMTGEAIDYLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIATEVSSKYVKLSWSPSPSAVTGYKVLLIPMTTGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGLTSSEPVSIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDINFSEVTSNSLKTSWSPAGENVFSYHITYKEATGDDQVTLVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGEETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRITYRPVAGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYVSGPGSPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWTRAPGKVKQYLITYTPVAGGDTQEVTVKGDTASTVLRGLNEGTQYALSVTALYASGAGDALFGEGTTLEERGSPGDLITKDITDTSIGAYWTSAPGMVRGYRVSWQSLYDDIETGEKSLPADVIHTVIENLQPETKYRVSIFATYSSGEGEPLSGEAMTELSEDSKTLKVDEETENTMRVTWKPAPGKVVNYRVMYRPRGGGRQMVAKVSPTVTSTVLKRLQPQTTYDITVLPVYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHKDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDIHAYNVADFDSLSRIVDDLTNNLCNSVKGPGDLEAPSNLVLSERTHRSMRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLERSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDIGSTTMHVQWQPVGGATGYTVTYEPINATVPTKPKEMRLEPTVNDVQLSDLFPNTEYAVTVQAVLHDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVAWEPAPGKVRKYIVRYKTPEEEAKEVEVDRSRASTPLKDLFSQTLYTVSVSAVYEEGESPPVTAQETTHTVPAPTNLQITEVTPESFRGTWDHGASDVSLYRITWAPSGSADKMETILNGDENTLVFQNLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLNVRWDHAEGSPRQYKLFYAPTAGGPEELVPIPGNTNYAILRNLQPDTQYTVTVVPVYSEGDGGRTSDTGRTLVRGLARNVQVYNPTPNSLDVRWDSAPGPVQQYRIVYSPQDGTRPSESIVVPGNTYTVHLEQLIPDTPYSVNIVALYSDAEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIPVYEDGDGTHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVRWLAHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTDLSPETDYGVTVFVQTPNLEGPGVSVKERTTLKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFHTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSSYRLQKNAFVNQPTVELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKALFYGSFHKVHIVVTSKSVKIYIDCYEIVEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGVSGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPQGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3065 }, "evidence": [ { "id": "A0A1L1RPW4", "url": "https://omabrowser.org/oma/group/A0A1L1RPW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RQI0-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 3065 }, "evidence": [ { "id": "A0A1L1RPW4", "url": "https://omabrowser.org/oma/group/A0A1L1RPW4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P70560-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PGEPGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGTPGSPGVAGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSNRNQPGPPGPPGPPGAAGARGEPGPGGAPGFPGRPGVQGPPGERGLPGEKGERGIGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPDREPFIVPVEPERTAEYEDDYGADEPEQQHPDHRRWRRALRPGPGQ", "length": 317 }, "evidence": [ { "id": "A0A1L1RPW4", "url": "https://omabrowser.org/oma/group/A0A1L1RPW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60847-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTRLPRALAALGVALLLSSIEAEVDPPSDLNFKIIDENTVHMSWERPVDPIVGYRITVDPTTDGPTKEFTLAASTTETLLSDLIPETQYVVTITSYNEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYRREDLLAAVKKIPYKGGNTMTGDAIDYLVKNTFTESAGSRAGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLVVTELSSKYIRLSWDPSPSAVTGYKILLTPMAAGSRHHALSVGPQTTTLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDIIKAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLRFTQVTANSFKAEWSPPGDNVFSYHVTYKDANGDDEVTVVEPASSTSVVLNNLRPETLYLVNVTAEYEDGFSVPITGEETTAEVKGVPRNLKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEISVIAEYSSGPGSPLTGNAATEEVRGNPRDLRVSDATTSTLKLSWSRAPGKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKEGTQYDLSVTALYASGAGEALSGKGSTLEERGSPQNLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGETTLPGDAIHTMIENLQPETKYKISVFATYSSGEGEPVTGDATTELSQDSKILRVDEETEHTMRVTWKAAPGKVVNYRVVYRPQGGGRQMVAKVPPTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEELRAGTTYRVNVFGMFDGGESLPLVGQEMTTLSDTTVTPFLSSGMDCLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSKIVDDLTINLCNSVKGPGDLEAPTNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLDTSTVLKDLKPETDYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQAVLYDLTSEPAKAREVTLPLPRPQDVKLRDVTHSTMNVVWEPVLGKVRKYIVRYKTPDEEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGTSPPATAYDTTRRVPAPTNLQFTEVTPESFRGTWDHGASDVSLYRITWAPVGNPDKMETILNGDENTLVFENLNPNTPYEVSITAIYPDESESEDLSGTERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTITVGGRQNSVLLQKLKPDTPYTITVYSQYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLSVRWDHAEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVYTEGDGGRTSDTGRTLVRGLARNIQVYNPTPNSLDVRWDPAPGPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSPSQGRTLPRSGPRNIRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNIHIFDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQTTVKPTEAPTEPPTPSPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEVNPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAFVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFINQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYRPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQSFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGINGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPEREPFIVPVEPERTAEYEDDYGADEPDQQHPDHMRWRRALRPGPAE", "length": 3120 }, "evidence": [ { "id": "A0A1L1RPW4", "url": "https://omabrowser.org/oma/group/A0A1L1RPW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99715-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3063 }, "evidence": [ { "id": "A0A1L1RPW4", "url": "https://omabrowser.org/oma/group/A0A1L1RPW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1765, "end_pos": 1767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1969, "end_pos": 1971, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2175, "end_pos": 2177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2208, "end_pos": 2210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2271, "end_pos": 2273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2530, "end_pos": 2532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2681, "end_pos": 2683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2301, 2305, 2827, 2852, 2887 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1004, "end_pos": 1006 }, { "start_pos": 1042, "end_pos": 1044 }, { "start_pos": 1510, "end_pos": 1512 }, { "start_pos": 1765, "end_pos": 1767 }, { "start_pos": 1969, "end_pos": 1971 }, { "start_pos": 2175, "end_pos": 2177 }, { "start_pos": 2208, "end_pos": 2210 }, { "start_pos": 2271, "end_pos": 2273 }, { "start_pos": 2530, "end_pos": 2532 }, { "start_pos": 2681, "end_pos": 2683 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1432 }, { "field": "total_sites", "count": 1135 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1394 }, { "field": "total_sites", "count": 1120 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 38 }, { "field": "total_sites", "count": 33 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P950-1", "uniprot_ac": "A0A1D5P950", "uniprot_id": "A0A1D5P950_CHICK", "mass": { "chemical_mass": 140263.0, "monoisotopic_mass": 140263.0 }, "refseq": { "ac": "XP_422804", "name": "histone-lysine N-methyltransferase MECOM isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422804" }, "gene_names": [ { "name": "MECOM", "type": "recommended", "evidence": [ { "id": "A0A1D5P950", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ] }, { "name": "MECOM", "type": "synonym", "evidence": [ { "id": "XP_422804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422804" } ] } ], "protein_names": [ { "name": "[histone H3]-lysine(9) N-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A1D5P950", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.367", "type": "synonym", "evidence": [ { "id": "A0A1D5P950", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950/entry#names_and_taxonomy" } ] }, { "name": "histone-lysine N-methyltransferase MECOM isoform X4", "type": "synonym", "evidence": [ { "id": "XP_422804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422804" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_422804.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422804" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MECOM", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950", "locus": { "chromosome": "9", "start_pos": 19984838, "end_pos": 19664339, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016901", "url": "https://www.ensembl.org/id/ENSGALG00010016901" } ] } } ], "crossref": [ { "id": "A0A1D5P950", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P950", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032577", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032577", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424997", "url": "https://www.ncbi.nlm.nih.gov/gene/424997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P950", "url": "https://www.orthodb.org/?gene=A0A1D5P950", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P950-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNY7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSKGRARKLAASDECLYESFPELPLEDVPEADGEAANAQCPASVSIQEPSSPTTSSEAFTPKESSPYKATIYIPDDIPIPSEFELRESNIPGAGLGIWTKRKIEVGEKFGPFVGEQRPHLKDPSYGWEILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRIWMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1245, "header": "tr|A0A1D5P950-1|A0A1D5P950_CHICK Isoform 1 of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P950-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950/entry", "sequence": { "sequence": "MRSKGRARKLAASDECLYESFPELPLEDVPEADGEAANAQCPASVSIQEPSSPTTSSEAFTPKESSPYKATIYIPDDIPIPSEFELRESNIPGAGLGIWTKRKIEVGEKFGPFVGEQRPHLKDPSYGWEILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRIWMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1245, "header": "tr|A0A1D5P950-1|A0A1D5P950_CHICK Isoform 1 of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19683461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040802.1", "url": "https://www.ensembl.org/id/ENSGALT00010040802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023766.1", "url": "https://www.ensembl.org/id/ENSGALP00010023766.1" } ] } }, { "isoform_ac": "A0A1D5PNY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY7/entry", "sequence": { "sequence": "MRSKGRARKLAASDECLYESFPELPLEDVPEADGEAANAQCPASVSIQEPSSPTTSSEAFTPKESSPYKATIYIPDDIPIPSEFELRESNIPGAGLGIWTKRKIEVGEKFGPFVGEQRPHLKDPSYGWEILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1236, "header": "tr|A0A1D5PNY7-1|A0A1D5PNY7_CHICK Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=2 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19683461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040805.1", "url": "https://www.ensembl.org/id/ENSGALT00010040805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023769.1", "url": "https://www.ensembl.org/id/ENSGALP00010023769.1" } ] } }, { "isoform_ac": "A0A8V0YRU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRU9/entry", "sequence": { "sequence": "MRILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1108, "header": "tr|A0A8V0YRU9-1|A0A1D5P950_CHICK Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19940809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040790.1", "url": "https://www.ensembl.org/id/ENSGALT00010040790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023754.1", "url": "https://www.ensembl.org/id/ENSGALP00010023754.1" } ] } }, { "isoform_ac": "A0A8V0YRV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRV5/entry", "sequence": { "sequence": "MQCFKTWLQFQAPDPSWSVLQILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1127, "header": "tr|A0A8V0YRV5-1|A0A1D5P950_CHICK Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19855675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040795.1", "url": "https://www.ensembl.org/id/ENSGALT00010040795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023759.1", "url": "https://www.ensembl.org/id/ENSGALP00010023759.1" } ] } }, { "isoform_ac": "A0A8V0YYP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP6/entry", "sequence": { "sequence": "MQSRASAVLGPHGIQQMFFPAKRDECLYESFPELPLEDVPEADGEAANAQCPASVSIQEPSSPTTSSEAFTPKESSPYKATIYIPDDIPIPSEFELRESNIPGAGLGIWTKRKIEVGEKFGPFVGEQRPHLKDPSYGWEILDEFCNVKFCIDASQPDVGNWLKYIKFAGCYDQHNLVACQISDQIFYRVVADIEPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELVDHQKFPCSTPHSAFSMVEEDFQKKLENENDLRDVHEIQECKECDQVFPDLQSLEKHMLSHSEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMNHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLLPTSSPVKGLPSADQTNKSQSPLMTNPQILPATQDILKALNKQPSVGENKPVELQPERSSEERPHEKLSDQSESSDLDDVSTPSGSDLETTSGSDLESDIESEKEKFKENGKMFKDKVSSLQSLASINNKKEHSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRPLPLKVEPQSPSELKKIPKGSSESPFDLTTKRKEEKPVTPIPSKPAAPPAASQDQPLDLSMGSRSRASSTKQAEPRKNHVFGEKKGGDLEQRKTSEASLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEANEMIQSMPSMFNFRAPPSALPETLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDSYFTEIRNFIGNSNHNNQSPRNSEERMNGSHFKDEKAMVTSQNSDLLDDEEAEDEVMMDEEDEESEIAGKTVKEPVTSDIHEGTPEEDYEETSTLDMNCKASPGRYKEEEYNKTGLSALDHIRHFTDSLKMRKMEENQYSEAELAAFNTSQLPEDLKQPLYRKSKSQAYAMMLSLSDKDSLHSASHNSPNMWHSMARAAAESSAIQSISHV", "length": 1245, "header": "tr|A0A8V0YYP6-1|A0A1D5P950_CHICK Computationally mapped isoform of [histone H3]-lysine(9) N-methyltransferase OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19664538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040809.1", "url": "https://www.ensembl.org/id/ENSGALT00010040809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023773.1", "url": "https://www.ensembl.org/id/ENSGALP00010023773.1" } ] } }, { "isoform_ac": "A0A8V0Z5E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E9/entry", "sequence": { "sequence": 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"length": 1114, "header": "tr|A0A8V0Z5E9-1|A0A8V0Z5E9_CHICK Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Gallus gallus OX=9031 GN=MECOM PE=4 SV=1 CANONICAL=A0A1D5P950-1" }, "locus": { "chromosome": "9", "start_pos": 19983518, "end_pos": 19941166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040786.1", "url": "https://www.ensembl.org/id/ENSGALT00010040786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023750.1", "url": "https://www.ensembl.org/id/ENSGALP00010023750.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 453, "start_aa": "Thr", "end_pos": 453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr453", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "histone H3K9 monomethyltransferase activity", "id": "GO:0140948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140948", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P950", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1146, "end_pos": 1148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1182, "end_pos": 1184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8943817", "name": "MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6G2-1", "A0A8V0XZM3-1", "A0A1D5P1F4-1", "A0A1D5P950-1" ], "evidence": [ { "id": "R-GGA-8943817", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943817" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P1F4", "gene_name": "RNF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P1F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P1F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F4" } ] } ] }, { "uniprot_ac": "A0A1D5P950", "gene_name": "MECOM", "activity": [ { "ec_number": "2.1.1.367", "activity": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A1D5P950", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ] }, { "ec_number": "2.1.1.367", "activity": "", "evidence": [ { "id": "A0A1D5P950", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P950" } ] } ] }, { "uniprot_ac": "A0A8V0X6G2", "gene_name": "", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0X6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0X6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6G2" } ] } ] }, { "uniprot_ac": "A0A8V0XZM3", "gene_name": "EZH2", "activity": [ { "ec_number": "2.1.1.356", "activity": "L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A8V0XZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZM3" } ] }, { "ec_number": "2.1.1.356", "activity": "", "evidence": [ { "id": "A0A8V0XZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZM3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P950-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1245, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P950-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P950" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.367", "ec_name": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.367", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.367" }, { "id": "2.1.1.367", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.367" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 453 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1009, "end_pos": 1011 }, { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 1062, "end_pos": 1064 }, { "start_pos": 1146, "end_pos": 1148 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P997-1", "uniprot_ac": "A0A1D5P997", "uniprot_id": "A0A1D5P997_CHICK", "mass": { "chemical_mass": 44682.0, "monoisotopic_mass": 44682.0 }, "refseq": { "ac": "NP_001239327", "name": "arfaptin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327" }, "gene_names": [ { "name": "ARFIP1", "type": "recommended", "evidence": [ { "id": "A0A1D5P997", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ] }, { "name": "ARFIP1", "type": "synonym", "evidence": [ { "id": "NP_001239327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327" } ] } ], "protein_names": [ { "name": "ADP ribosylation factor interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5P997", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997/entry#names_and_taxonomy" } ] }, { "name": "arfaptin 1", "type": "synonym", "evidence": [ { "id": "NP_001239327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327" } ] }, { "name": "arfaptin-1", "type": "synonym", "evidence": [ { "id": "NP_001239327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.147186.1, SRR13267655.184751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Nov 16, 2011 this sequence version replaced XP_001233078.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARFIP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997", "locus": { "chromosome": "4", "start_pos": 33504253, "end_pos": 33463463, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007663", "url": "https://www.ensembl.org/id/ENSGALG00010007663" } ] } } ], "crossref": [ { "id": "A0A1D5P997", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P997", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041361", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041361", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770884", "url": "https://www.ncbi.nlm.nih.gov/gene/770884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770884", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P997", "url": "https://www.orthodb.org/?gene=A0A1D5P997", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPB5", "url": "https://www.orthodb.org/?gene=A0A8V0XPB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTM0", "url": "https://www.orthodb.org/?gene=A0A8V0XTM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVL0", "url": "https://www.orthodb.org/?gene=A0A8V0XVL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XYB3", "url": "https://www.orthodb.org/?gene=A0A8V0XYB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1G6", "url": "https://www.orthodb.org/?gene=A0A8V0Y1G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12141:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12141:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001239327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P997-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGSSASPKSTVISASSAAASRLAGQGCDLIIPTGGRAQQKSGPVVLDEVKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLLTVKQYESARIEYDAYRTDLEELNLGPRDASTLPKIEQSQQMFQVHKEKYDKMRNDVSIKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLQQFHIKLKTPGADAPSWLEEQ", "length": 402, "header": "tr|A0A1D5P997-1|A0A1D5P997_CHICK Isoform 1 of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P997-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997/entry", "sequence": { "sequence": "MSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGSSASPKSTVISASSAAASRLAGQGCDLIIPTGGRAQQKSGPVVLDEVKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLLTVKQYESARIEYDAYRTDLEELNLGPRDASTLPKIEQSQQMFQVHKEKYDKMRNDVSIKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLQQFHIKLKTPGADAPSWLEEQ", "length": 402, "header": "tr|A0A1D5P997-1|A0A1D5P997_CHICK Isoform 1 of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33502811, "end_pos": 33467504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018254.1", "url": "https://www.ensembl.org/id/ENSGALT00010018254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010031.1", "url": "https://www.ensembl.org/id/ENSGALP00010010031.1" } ] } }, { "isoform_ac": "A0A8V0XPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPB5/entry", "sequence": { "sequence": "MSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGSSASPKSTVISASSAAASRLAGQGGRAQQKSGPVVLDEVKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLLTVKQYESARIEYDAYRTDLEELNLGPRDASTLPKIEQSQQMFQVHKEKYDKMRNDVSIKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLQQFHIKLKTPGADAPSWLEEQ", "length": 394, "header": "tr|A0A8V0XPB5-1|A0A1D5P997_CHICK Computationally mapped isoform of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33502811, "end_pos": 33467504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018255.1", "url": "https://www.ensembl.org/id/ENSGALT00010018255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010032.1", "url": "https://www.ensembl.org/id/ENSGALP00010010032.1" } ] } }, { "isoform_ac": "A0A8V0XTM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTM0/entry", "sequence": { "sequence": "MSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGYS", "length": 101, "header": "tr|A0A8V0XTM0-1|A0A1D5P997_CHICK Computationally mapped isoform of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33480122, "end_pos": 33467504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018247.1", "url": "https://www.ensembl.org/id/ENSGALT00010018247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010026.1", "url": "https://www.ensembl.org/id/ENSGALP00010010026.1" } ] } }, { "isoform_ac": "A0A8V0XVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVL0/entry", "sequence": { "sequence": "MYADLVYQSITKREISQLLQDLHIKYFNIDHSVCSKTNTNLFLLVQQEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGGRAQQKSGPVVLDEVKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLLTVKQYESARIEYDAYRTDLEELNLGPRDASTLPKIEQSQQMFQVHKEKYDKMRNDVSIKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLQQFHIKLKTPGADAPSWLEEQ", "length": 391, "header": "tr|A0A8V0XVL0-1|A0A1D5P997_CHICK Computationally mapped isoform of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33502811, "end_pos": 33470140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018252.1", "url": "https://www.ensembl.org/id/ENSGALT00010018252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010029.1", "url": "https://www.ensembl.org/id/ENSGALP00010010029.1" } ] } }, { "isoform_ac": "A0A8V0XYB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYB3/entry", "sequence": { "sequence": "MLAGHRAGPCPGGGMSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGGRAQQKSGPVVLDEVKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLLTVKQYESARIEYDAYRTDLEELNLGPRDASTLPKIEQSQQMFQVHKEKYDKMRNDVSIKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLQQFHIKLKTPGADAPSWLEEQ", "length": 384, "header": "tr|A0A8V0XYB3-1|A0A1D5P997_CHICK Computationally mapped isoform of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33502811, "end_pos": 33463810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018253.1", "url": "https://www.ensembl.org/id/ENSGALT00010018253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010030.1", "url": "https://www.ensembl.org/id/ENSGALP00010010030.1" } ] } }, { "isoform_ac": "A0A8V0Y1G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G6/entry", "sequence": { "sequence": "MSEHRNESTALDEIHPAGEEVQSDSEEGAMAQESPKNSAAEIPVTSNGQLEDSHEHSFNRDLKRSLPAGLGLSETKITSHDFDSTKEGVVEAGTFPGKGITALNG", "length": 105, "header": "tr|A0A8V0Y1G6-1|A0A1D5P997_CHICK Computationally mapped isoform of ADP ribosylation factor interacting protein 1 OS=Gallus gallus OX=9031 GN=ARFIP1 PE=1 SV=1 CANONICAL=A0A1D5P997-1" }, "locus": { "chromosome": "4", "start_pos": 33481726, "end_pos": 33467504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018250.1", "url": "https://www.ensembl.org/id/ENSGALT00010018250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010028.1", "url": "https://www.ensembl.org/id/ENSGALP00010010028.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770884", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770884", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of retrograde transport, endosome to Golgi", "id": "GO:1905280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905280", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P997", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P997" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P997-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P997-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P997" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5P9T4-1", "uniprot_ac": "A0A1D5P9T4", "uniprot_id": "A0A1D5P9T4_CHICK", "mass": { "chemical_mass": 102591.0, "monoisotopic_mass": 102591.0 }, "refseq": { "ac": "XP_015147673", "name": "protein unc-45 homolog A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" }, "gene_names": [ { "name": "UNC45A", "type": "recommended", "evidence": [ { "id": "A0A1D5P9T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ] }, { "name": "UNC45A", "type": "synonym", "evidence": [ { "id": "XP_015147673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" } ] } ], "protein_names": [ { "name": "Protein unc-45 homolog A", "type": "recommended", "evidence": [ { "id": "A0A1D5P9T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry#names_and_taxonomy" } ] }, { "name": "protein unc-45 homolog A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015147673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC45A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4", "locus": { "chromosome": "10", "start_pos": 20103430, "end_pos": 20112395, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000056", "url": "https://www.ensembl.org/id/ENSGALG00010000056" } ] } } ], "crossref": [ { "id": "A0A1D5P9T4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P9T4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029714", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029714", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415584", "url": "https://www.ncbi.nlm.nih.gov/gene/415584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P9T4", "url": "https://www.orthodb.org/?gene=A0A1D5P9T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0WZD8", "url": "https://www.orthodb.org/?gene=A0A8V0WZD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X639", "url": "https://www.orthodb.org/?gene=A0A8V0X639", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P9T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X639", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X639", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X639-1", "url": 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Isoform 1 of Protein unc-45 homolog A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P9T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry", "sequence": { "sequence": 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Isoform 1 of Protein unc-45 homolog A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20112356, "end_pos": 20106229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000090.1", "url": "https://www.ensembl.org/id/ENSGALT00010000090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000066.1", "url": "https://www.ensembl.org/id/ENSGALP00010000066.1" } ] } }, { "isoform_ac": "A0A8V0WZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZD8/entry", "sequence": { "sequence": "MEETVTAGQLRERGNALFQAGDHAAALAAYTQALSLCQAEPERAVLHRNRAACYLKLEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVAWAARPRQPGIRAAAAAGGGSGRCAHAGGGSWRVALGLCQRRGRPLCVGLERVGPTGAALPGGGRGAGRG", "length": 915, "header": "tr|A0A8V0WZD8-1|A0A1D5P9T4_CHICK Computationally mapped isoform of Protein unc-45 homolog A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20112356, "end_pos": 20103447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000091.1", "url": "https://www.ensembl.org/id/ENSGALT00010000091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000067.1", "url": "https://www.ensembl.org/id/ENSGALP00010000067.1" } ] } }, { "isoform_ac": "A0A8V0X639-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X639/entry", "sequence": { "sequence": "MGSVRDPAWAVFWEGQDTALCCFPVLRGVVSIPELHGCFFACFVKQCAQQEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVTVHWLEILQALLLSPSAELQHRGAVVVMNMMAAAREVAEQLIASEMLEILSVLAKDEDKPRVAQAAQESLARAVAYGLIEPNPRQQ", "length": 924, "header": "tr|A0A8V0X639-1|A0A1D5P9T4_CHICK Computationally mapped isoform of Protein unc-45 homolog A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20111738, "end_pos": 20106229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000089.1", "url": "https://www.ensembl.org/id/ENSGALT00010000089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000065.1", "url": "https://www.ensembl.org/id/ENSGALP00010000065.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P9T4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 931, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P9T4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5P9T4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5P9T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4" }, { "id": "PF11701", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11701" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UNC-45/Cro1/She4 central", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 516, "start_aa": "Asn", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PAD2-1", "uniprot_ac": "A0A1D5PAD2", "uniprot_id": "A0A1D5PAD2_CHICK", "mass": { "chemical_mass": 135897.0, "monoisotopic_mass": 135897.0 }, "refseq": { "ac": "XP_015148308", "name": "RNA-binding protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148308" }, "gene_names": [ { "name": "RBM6", "type": "recommended", "evidence": [ { "id": "A0A1D5PAD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ] }, { "name": "RBM6", "type": "synonym", "evidence": [ { "id": "XP_015148308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148308" } ] } ], "protein_names": [ { "name": "RNA binding motif protein 6", "type": "synonym", "evidence": [ { "id": "A0A1D5PAD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148308" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148308" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2", "locus": { "chromosome": "12", "start_pos": 2813704, "end_pos": 2759412, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027327", "url": "https://www.ensembl.org/id/ENSGALG00010027327" } ] } } ], "crossref": [ { "id": "A0A1D5PAD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PAD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035578", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035578", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12314", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12314", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16163", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16163", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415931", "url": "https://www.ncbi.nlm.nih.gov/gene/415931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415931", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNIPHAD", "url": "https://omabrowser.org/oma/group/RNIPHAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PAD2", "url": "https://www.orthodb.org/?gene=A0A1D5PAD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3R0", "url": "https://www.orthodb.org/?gene=A0A8V1A3R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG22", "url": "https://www.orthodb.org/?gene=A0A8V1AG22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13948:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13948:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PAD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGDHRQGNRTGSFRGSQEERFAPGWNRDYPPSLDSLAQERHSGNFSGRESLPFDIQALAGLLNPQFANREEPSFSFGARDGPRSDFRGGEGHHDFRGRDFPPSDFQSRDESQLDFRGREPPPSEYRGRDMYSGDFREREGPPMDFRGGDIPPVDYRNRETFRMNYRDREAHSMDYRGRDEPPSDFRGRGSFDLDFRGRDGSHSDFRARDVPELDYRGRDHSYSDFRNRDVPDLDFRGVGTSDLDFRNRNAPSSDFRNRHRSRSDQDFRSRDMPPPMDFSDREMPPVDQSLVDFRRNQSTIPLAEREGSGLNTGKREEPALGLERTPFGSQKGEFQHSEAPAREEESLGLGLKDNASHNFQNSRGPLPALQDQEEQPQTFANKQQQQQQLSGGEQQRSDSDLGLKGEDDLDFLGRQDTDYRNIEYRDVDHRLPACQLFDYEHGKSFSEGKPSKDSRPYKSLQDQDYRTCPEFVKPSKLIRLGGVPETATKDDILNAFRGPDGMPVKNLRLKDYSSGYDYRYVCVEFSLLEEAIGCMEANQGTLTIGGEEVTLEYTLCPEFWRCKRCKVCNVGYRSSCSYCKLPRDGNRAGSESKGGPEGEDASSEQEFTAETKLEKPEQELPVQPGSPKQPLQASDPAPQQECQPQEQEPRKRDEGRERRPSQEKRRDTDRHQELPSQREGEEATPQEGGGSRTIMLKRITRFTPPEVIVGLLAPYVRISTSNVRIMKNKAGRMGQTYGFIELDSHAEALRLLKILQNLDPPICIDGRTLEVNLATGRRRNDYGEHGDNSYYNQGRRGMRDRRGGESQRRTRAQSPSDVSTYIYDPETGNYYDPIAGTYYDPRTQREVTIDREPCSSPPENRRRRHESQERTSERKEPHSRDNRDKKEKGKNTPAKNEPGEERFFTEDVFKKPLPPSVKKDETAGLNDCGEEKFFAEDVFKKPLPPSVKKDESAARPKVVNPLIGLLGEYGGDSDNEEEEEEEEQAQWLPSPHPPAQREEQPRRAKAGDDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSNLHKQNLEIHMKIKRSEQELAYLEKREREGRYKDKGNDRREKFQQMDSPERKRFRYDRGPESDYDPRIDSNNKGNRMLQSTGWKKGFGHNQQGTTSPMEAENRKRGPGLGAQGRPNRRQSNETYRDAVRRVMFARYKELE", "length": 1180, "header": "tr|A0A1D5PAD2-1|A0A1D5PAD2_CHICK Isoform 1 of RNA binding motif protein 6 OS=Gallus gallus OX=9031 GN=RBM6 PE=1 SV=2 CANONICAL=A0A1D5PAD2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PAD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2/entry", "sequence": { "sequence": "MWGDHRQGNRTGSFRGSQEERFAPGWNRDYPPSLDSLAQERHSGNFSGRESLPFDIQALAGLLNPQFANREEPSFSFGARDGPRSDFRGGEGHHDFRGRDFPPSDFQSRDESQLDFRGREPPPSEYRGRDMYSGDFREREGPPMDFRGGDIPPVDYRNRETFRMNYRDREAHSMDYRGRDEPPSDFRGRGSFDLDFRGRDGSHSDFRARDVPELDYRGRDHSYSDFRNRDVPDLDFRGVGTSDLDFRNRNAPSSDFRNRHRSRSDQDFRSRDMPPPMDFSDREMPPVDQSLVDFRRNQSTIPLAEREGSGLNTGKREEPALGLERTPFGSQKGEFQHSEAPAREEESLGLGLKDNASHNFQNSRGPLPALQDQEEQPQTFANKQQQQQQLSGGEQQRSDSDLGLKGEDDLDFLGRQDTDYRNIEYRDVDHRLPACQLFDYEHGKSFSEGKPSKDSRPYKSLQDQDYRTCPEFVKPSKLIRLGGVPETATKDDILNAFRGPDGMPVKNLRLKDYSSGYDYRYVCVEFSLLEEAIGCMEANQGTLTIGGEEVTLEYTLCPEFWRCKRCKVCNVGYRSSCSYCKLPRDGNRAGSESKGGPEGEDASSEQEFTAETKLEKPEQELPVQPGSPKQPLQASDPAPQQECQPQEQEPRKRDEGRERRPSQEKRRDTDRHQELPSQREGEEATPQEGGGSRTIMLKRITRFTPPEVIVGLLAPYVRISTSNVRIMKNKAGRMGQTYGFIELDSHAEALRLLKILQNLDPPICIDGRTLEVNLATGRRRNDYGEHGDNSYYNQGRRGMRDRRGGESQRRTRAQSPSDVSTYIYDPETGNYYDPIAGTYYDPRTQREVTIDREPCSSPPENRRRRHESQERTSERKEPHSRDNRDKKEKGKNTPAKNEPGEERFFTEDVFKKPLPPSVKKDETAGLNDCGEEKFFAEDVFKKPLPPSVKKDESAARPKVVNPLIGLLGEYGGDSDNEEEEEEEEQAQWLPSPHPPAQREEQPRRAKAGDDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSNLHKQNLEIHMKIKRSEQELAYLEKREREGRYKDKGNDRREKFQQMDSPERKRFRYDRGPESDYDPRIDSNNKGNRMLQSTGWKKGFGHNQQGTTSPMEAENRKRGPGLGAQGRPNRRQSNETYRDAVRRVMFARYKELE", "length": 1180, "header": "tr|A0A1D5PAD2-1|A0A1D5PAD2_CHICK Isoform 1 of RNA binding motif protein 6 OS=Gallus gallus OX=9031 GN=RBM6 PE=1 SV=2 CANONICAL=A0A1D5PAD2-1" }, "locus": { "chromosome": "12", "start_pos": 2813520, "end_pos": 2763893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066252.1", "url": "https://www.ensembl.org/id/ENSGALT00010066252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040518.1", "url": "https://www.ensembl.org/id/ENSGALP00010040518.1" } ] } }, { "isoform_ac": "A0A8V1A3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3R0/entry", "sequence": { "sequence": "MWGDHRQGNRTGSFRGSQEERFAPGWNRDYPPSLDSLAQERHSGNFSGRESLPFDIQALAGLLNPQFANREEPSFSFGARDGPRSDFRGGEGHHDFRGRDFPPSDFQSRDESQLDFRGREPPPSEYRGRDMYSGDFREREGPPMDFRGGDIPPVDYRNRETFRMNYRDREAHSMDYRGRDEPPSDFRGRGSFDLDFRGRDGSHSDFRARDVPELDYRGRDHSYSDFRNRDVPDLDFRGVGTSDLDFRNRNAPSSDFRNRHRSRSDQDFRSRDMPPPMDFSDREMPPVDQSLVDFRRNQSTIPLAEREGSGLNTGKREEPALGLERTPFGSQKGEFQHSEAPAREEESLGLGLKDNASHNFQNSRGPLPALQDQEEQPQTFANKQQQQQQLSGGEQQRSDSDLGLKGEDDLDFLGRQDTDYRNIEYRDVDHRLPACQLFDYEHGKSFSEGKPSKDSRPYKSLQDQDYRTCPEFVKPSKLIRLGGVPETATKDDILNAFRGPDGMPVKNLRLKDYSSGYDYRYVCVEFSLLEEAIGCMEANQGTLTIGGEEVTLEYTLCPEFWRCKRCKVCNVGYRSSCSYCKLPRDGNRAGSESKGGPEGEDASSEQEFTETKLEKPEQELPVQPGSPKQPLQASDPAPQQECQPQEQEPRKRDEGRERRPSQEKRRDTDRHQELPSQREGEEATPQEGGGSRTIMLKRITRFTPPEVIVGLLAPYVRISTSNVRIMKNKAGRMGQTYGFIELDSHAEALRLLKILQNLDPPICIDGRTLEVNLATGRRRNDYGEHGDNSYYNQGRRGMRDRRGGESQRRTRAQSPSDVSTYIYDPETGNYYDPIAGTYYDPRTQREVTIDREPCSSPPENRRRRHESQERTSERKEPHSRDNRDKKEKGKNTPAKNEPGEERFFTEDVFKKPLPPSVKKDETAGLNDCGEEKFFAEDVFKKPLPPSVKKDESAARPKVVNPLIGLLGEYGGDSDNEEEEEEEEQAQWLPSPHPPAQREEQPRRAKAGDDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSNLHKQNLEIHMKIKRSEQELAYLEKREREGRYKDKGNDRREKFQQMDSPERKRFRYDRGPESDYDPRIDSNNKGNRMLQSTGWKKGFGHNQQGTTSPMEAENRKRGPGLGAQGRPNRRQSNETYRDAVRRVMFARYKELE", "length": 1179, "header": "tr|A0A8V1A3R0-1|A0A1D5PAD2_CHICK Computationally mapped isoform of RNA binding motif protein 6 OS=Gallus gallus OX=9031 GN=RBM6 PE=1 SV=1 CANONICAL=A0A1D5PAD2-1" }, "locus": { "chromosome": "12", "start_pos": 2813520, "end_pos": 2763893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066254.1", "url": "https://www.ensembl.org/id/ENSGALT00010066254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040520.1", "url": "https://www.ensembl.org/id/ENSGALP00010040520.1" } ] } }, { "isoform_ac": "A0A8V1AG22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG22/entry", "sequence": { "sequence": "MWIATIINPLIFGSQEERFAPGWNRDYPPSLDSLAQERHSGNFSGRESLPFDIQALAGLLNPQFANREEPSFSFGARDGPRSDFRGGEGHHDFRGRDFPPSDFQSRDESQLDFRGREPPPSEYRGRDMYSGDFREREGPPMDFRGGDIPPVDYRNRETFRMNYRDREAHSMDYRGRDEPPSDFRGRGSFDLDFRGRDGSHSDFRARDVPELDYRGRDHSYSDFRNRDVPDLDFRGVGTSDLDFRNRNAPSSDFRNRHRSRSDQDFRSRDMPPPMDFSDREMPPVDQSLVDFRRNQSTIPLAEREGSGLNTGKREEPALGLERTPFGSQKGEFQHSEAPAREEESLGLGLKDNASHNFQNSRGPLPALQDQEEQPQTFANKQQQQQQLSGGEQQRSDSDLGLKGEDDLDFLGRQDTDYRNIEYRDVDHRLPACQLFDYEHGKSFSEGKPSKDSRPYKSLQDQDYRTCPEFVKPSKLIRLGGVPETATKDDILNAFRGPDGMPVKNLRLKDYSSGYDYRYVCVEFSLLEEAIGCMEANQGTLTIGGEEVTLEYTLCPEFWRCKRCKVCNVGYRSSCSYCKLPRDGNRAGSESKGGPEGEDASSEQEFTETKLEKPEQELPVQPGSPKQPLQASDPAPQQECQPQEQEPRKRDEGRERRPSQEKRRDTDRHQELPSQREGEEATPQEGGGSRSEWQRLRKCWQVALSKVNSGQAEALRLLKILQNLDPPICIDGRTLEVNLATGRRRYGQMRRGMRDRRGGESQRRTRAQSPSDVSTYIYDPETGNYYDPIAGTYYDPRTQREVTIDREPCSSPPENRRRRHESQERTSERKEPHSRDNRDKKEKGKNTPAKNEPGEERFFTEDVFKKPLPPSVKKDETAGLNDCGEEKFFAEDVFKKPLPPSVKKDESAARVRQSMGTLPWLSQGECLGSSPKPGSDLQWQKCQFLMLAEEALAMEWQRQFAS", "length": 961, "header": "tr|A0A8V1AG22-1|A0A1D5PAD2_CHICK Computationally mapped isoform of RNA binding motif protein 6 OS=Gallus gallus OX=9031 GN=RBM6 PE=1 SV=1 CANONICAL=A0A1D5PAD2-1" }, "locus": { "chromosome": "12", "start_pos": 2808492, "end_pos": 2765661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066250.1", "url": "https://www.ensembl.org/id/ENSGALT00010066250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040516.1", "url": "https://www.ensembl.org/id/ENSGALP00010040516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415931", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MIY9-1", "protein_name": "RNA-binding protein 6 isoform X1", "gene_name": "Rbm6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWGDSRSANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGRDSLPFDFQGHSGPPFANVEEHSFSYGARDGPHGDYQGGEGPGHDFRGGDFSSSDFQSRDSAQLDFRNRDMHSGDFRDREGPPMDYRGGDGTPMDYRGRETPHMNYRDRDSHPIDFRSRDVPPSDFRGRGTYDLDFRGRDGSHADFRGRDLSDLDFRSRDQSRSDFRNRDVSDLDLRDKEGTQVDFRGRGSATTDLDFRSRDAAHSDFRGRHRSRTYQDFRGREVGPCMEFKDREMPPVDPKILDYIQPSTQEREHSGVNVNKREEPTHDHAMEMAAFGVQKGEFEHSETREGETQSGTFEHESPSDFQNSQSPVQDQDKPKLPGGEQQSSDAGLFKEEGDLDFLGRQDTDYRNIEYCDVDHRLPGSQIFGYGQNKSFPQGKMSRDAQQELQDQDYRTGPSEEKPNRLIRLSGVPKNATKEEILNAFRTSDGIPVKELQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIHDKEVTLEYVPSPDFWYCKRCKASTGGHQSSCSFCKGPKEEVKQELVSYPQPQKTSIPVPSEKQPNQPRPADKEHEFRKREEGQESRSGHQKRDSERYFPHSRREGLTFRRDREKESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVHLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGNRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPESPEEEESKEKKSTSQGKSSSKKETSKRDSKEKKDRGVTKFQESTSEGKSPPEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQAPPVQLRTAQPQQREELTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGRFKERGNDRREKLQSFDSPERKRIKYSRETDSDRNPVDKEDTDTNSKGGCAQQAAGWRKGTGLGYSHPGLGSSEETEGRMRGPGGAPGRTSKRQSNETYRDAVRRVMFARYKELD", "length": 1119 }, "evidence": [ { "id": "A0A1D5PAD2", "url": "https://omabrowser.org/oma/group/A0A1D5PAD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BC65-1", "protein_name": "RNA binding motif protein 6", "gene_name": "RBM6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWGDSRSANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGRDSLPFDFQGHSGPPFANVEEHSFSYGARDGQHGDYRGGEGHGHDFRGGDFSSSDFQSRDSSQLDFRGRDIHSGDLRDREGPPMDYRGGDGTSLDYRGRETSHMNYREREAHTGDFRGRDVPPPDFRGRGTYDLDFRGRDGARADFRGRDLSDLDFRARDQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGSGTSDLDFRDRNTPHADFRGRHRSRTDQDFRGREGGPCVEFKDREMPSADPDILDYVQPSTQNREHSGMNVNKREESAHDHTTERPAFGIQKGEFEHSETGEGEKQGVAFDHASSPDFQNSQSPLQDQDKSQHSGGEQQSSDAGMFKEEGGLDFLGRQDTDYRSMEYCDVDHRLPGSQIFGYGQSKSFPEGKTSQDAQRDLQDQDYRTGPSEEKPSKLIRLNGVPENATKEEILNAFWTPDGMPVKDLQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIHDKEVTLEYVPSLDFWYCKWCKASTGGHRSSCSFCKCPREEAKQELVTYPQPQKTSIPALSEKQASQPSRSADKESEPKKREEGQEPRLGHQKRESERYLPPRREGLTFRRDREKEPWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANIRIIKNRTGHMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIAGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDVNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGSPEEEDIKEKKPSSQGKSSSKKETSKRDSKEKKDRGVTRFQENASEGTAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPPQREELTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGRFKERGNDRREKLQSLDSPERKRIKYSRETDSDRKPVGKEGINSSSTGGYVQQATGWRKGAGLGYGHPGLGSAEETESRMRGPNVGAPGRTSKRQSNETYRDAVRRVMFARYKELD", "length": 1120 }, "evidence": [ { "id": "A0A1D5PAD2", "url": "https://omabrowser.org/oma/group/A0A1D5PAD2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAD2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PAD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1180, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PAD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PAD2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 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"uniprot_canonical_ac": "A0A1D5PAJ5-1", "uniprot_ac": "A0A1D5PAJ5", "uniprot_id": "A0A1D5PAJ5_CHICK", "mass": { "chemical_mass": 22460.0, "monoisotopic_mass": 22460.0 }, "refseq": { "ac": "XP_046758045", "name": "bMERB domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758045" }, "gene_names": [ { "name": "LOC101749287", "type": "recommended", "evidence": [ { "id": "A0A1D5PAJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAJ5" } ] }, { "name": "LOC101749287", "type": "synonym", "evidence": [ { "id": "XP_046758045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758045" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PAJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAJ5/entry#names_and_taxonomy" } ] }, { "name": "bMERB domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046758045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758045" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101749287", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAJ5", "locus": {} } ], "crossref": [ { "id": "A0A1D5PAJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PAJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030259", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": 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The reference sequence was derived from JAENSK010000087.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289026" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PAR2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAR2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PMAIP1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAR2", "locus": { "chromosome": "Z", "start_pos": 10001472, "end_pos": 9998272, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009024", "url": "https://www.ensembl.org/id/ENSGALG00010009024" } ] } } ], "crossref": [ { "id": "A0A1D5PAR2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PAR2", "database": "AlphaFoldDB", 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This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015145431.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05", "locus": { "chromosome": "7", "start_pos": 28057601, "end_pos": 28056055, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020798", "url": "https://www.ensembl.org/id/ENSGALG00010020798" } ] } } ], "crossref": [ { "id": "A0A1D5PB05", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PB05", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"https://www.uniprot.org/uniprotkb/A0A1D5PB05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVALLVAVPLLLLQAPAESGAHYEMMGTCRMICDPYSGARPPGPGSTAAVEALQDLGANPPPPFAQGPKGEPGRPGKPGPRGPPGEPGPPGPRGPPGERGDAGKPGLPGLPLAGAGGGGSGGGAAAGGEAAGGLSAAFGGPRIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYEPASGKFTCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 272, "header": "tr|A0A1D5PB05-1|A0A1D5PB05_CHICK Isoform 1 of Complement C1q like 2 OS=Gallus gallus OX=9031 GN=C1QL2 PE=4 SV=2 CANONICAL=A0A1D5PB05-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB05-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05/entry", "sequence": { "sequence": "MAVALLVAVPLLLLQAPAESGAHYEMMGTCRMICDPYSGARPPGPGSTAAVEALQDLGANPPPPFAQGPKGEPGRPGKPGPRGPPGEPGPPGPRGPPGERGDAGKPGLPGLPLAGAGGGGSGGGAAAGGEAAGGLSAAFGGPRIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYEPASGKFTCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 272, "header": "tr|A0A1D5PB05-1|A0A1D5PB05_CHICK Isoform 1 of Complement C1q like 2 OS=Gallus gallus OX=9031 GN=C1QL2 PE=4 SV=2 CANONICAL=A0A1D5PB05-1" }, "locus": { "chromosome": "7", "start_pos": 28057010, "end_pos": 28056055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050307.1", "url": "https://www.ensembl.org/id/ENSGALT00010050307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029718.1", "url": "https://www.ensembl.org/id/ENSGALP00010029718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107053871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053871", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3B0IP42-1", "protein_name": "Complement C1q like 2", "gene_name": "C1ql2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRVGLFDSPDQFQSGGLGSSGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTTSAAGGVGVVGGGTGGGGDTEGEVTSALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 266 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGE9-1", "protein_name": "Complement C1q like 2", "gene_name": "C1QL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMMGTCRMICDPYTAAPGAGPAGAKAPPPGPSTAALEVMQDLSINPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGAAGGVGVVGGGTGGGGDSEGEVTGALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9QE76-1", "protein_name": "Complement C1q-like protein 2", "gene_name": "c1ql2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIAALVIALPLLLRTPAAAHYEMMGTCRMICDPYNPKPSATALEVMQDLSAIPPAFAQGTRGEPGRPGKPGPRGPPGEPGPPGPRGPPGDSGRPGFTGVASGTARTETGDVGPALGNAKIAFYVGLKNPHEGYEVLRFDDVVTNVGNHYDPTTGKFTCQVSGIYYFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEIYVKLDGGKAHGGNNNKYSTFSGFILYPD", "length": 248 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RY08-1", "protein_name": "Complement C1q like 2", "gene_name": "C1QL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMMGTCRMICDPYSAAPGGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGAAGSVGVGGGGTGGGGDSEGEVTGALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z5L3-1", "protein_name": "Complement C1q-like protein 2", "gene_name": "C1QL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGLLIAVPLLLQAAPRGAAHYEMMGTCRMICDPYTAAPGGEPPGAKAQPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGTASGVGVVGGGAGVGGDSEGEVTSALSATFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CFR0-1", "protein_name": "Complement C1q-like protein 2", "gene_name": "C1ql2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMLGTCRMICDPYSVAPAGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTTSAAGGVGVVSGGTGGGGDTEGEVTSALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287 }, "evidence": [ { "id": "A0A1D5PB05", "url": "https://omabrowser.org/oma/group/A0A1D5PB05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "postsynaptic density assembly", "id": "GO:0097107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097107", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "maintenance of synapse structure", "id": "GO:0099558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099558", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "regulation of synapse maturation", "id": "GO:0090128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090128", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "trans-synaptic signaling, modulating synaptic transmission", "id": "GO:0099550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099550", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" }, { "name": "cerebellar climbing fiber to Purkinje cell synapse", "id": "GO:0150053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150053", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PB05-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 272, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PB05-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PB05" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PB60-1", "uniprot_ac": "A0A1D5PB60", "uniprot_id": "A0A1D5PB60_CHICK", "mass": { "chemical_mass": 94077.0, "monoisotopic_mass": 94077.0 }, "refseq": { "ac": "XP_015140743", "name": "probable ribonuclease ZC3H12B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140743" }, "gene_names": [ { "name": "ZC3H12B", "type": "recommended", "evidence": [ { "id": "A0A1D5PB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ] }, { "name": "ZC3H12B", "type": "synonym", "evidence": [ { "id": "XP_015140743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140743" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 12B", "type": "synonym", "evidence": [ { "id": "A0A1D5PB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60/entry#names_and_taxonomy" } ] }, { "name": "probable ribonuclease ZC3H12B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140743" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140743" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H12B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60", "locus": { "chromosome": "4", "start_pos": 54303, "end_pos": 39194, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015044", "url": "https://www.ensembl.org/id/ENSGALG00010015044" } ] } } ], "crossref": [ { "id": "A0A1D5PB60", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PB60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039391", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039391", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422175", "url": "https://www.ncbi.nlm.nih.gov/gene/422175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422175", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422175", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDPLPCT", "url": "https://omabrowser.org/oma/group/WDPLPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB60", "url": "https://www.orthodb.org/?gene=A0A1D5PB60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140743", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAWSMVGKLKMEKRHSREDRNVEQDAGECSAESEEWTSSESEPEQPYFRSSCSNIPWREKEVPPKPHRPLCRSPCLDRPSFSQSSITQDLKLEECKTNLDKEYQAKMDFALKLGYAGDQIQAVLNKLGADALINDVLAELVRLGNKSESEGQNSASSTTSTLVPRGPCPKEIASPELSLEDEVVDNSDNLRPIVIDGSNVAMSHGNKEGFSCRGIQLAVDWFLEKGHKDITVFVPAWRKEQSRPDAPITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQNEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVIPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSAVKTMSEGALAKCGTGPSSSKGEISSEVKRIAPKRQSDPSIRSVAVEPEEKLTVARKSEANSVPSLVSALSVPTLPPPKSHAAGALNTRSASSPVPGSSQFTHQKSSLEHMSSVQYPPILVTNSHGTSISYTDQYPKYESLGDHGYYSLLSDFSNLSISSMHNTDYYGADMDQGMYSRNSSPCPDNCLSHTNNDSYSSYNDLYLGVADASPEDNVKIHRLTSQNRLQPFPHGYHEALNRVQSFGTEEPQQSLRKQSVSHLGLHAQHPVVGARSSCPGEYPVPQNIHPSTAQPSRALVMTRMDSISDSRLYESNPTRQRRPPLCREQHASWDPLPCASDSYTYHSYPLSNNLMQPCYEPVMVRSMPEKMEQLWRNPWIGICGEPREPHIIPEHQYQTYKNLCNIFPPSIVLSVMEKNPHMTDAQQLAAMIVAKLRTGR", "length": 837, "header": "tr|A0A1D5PB60-1|A0A1D5PB60_CHICK Isoform 1 of Zinc finger CCCH-type containing 12B OS=Gallus gallus OX=9031 GN=ZC3H12B PE=3 SV=1 CANONICAL=A0A1D5PB60-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60/entry", "sequence": { "sequence": "MTAWSMVGKLKMEKRHSREDRNVEQDAGECSAESEEWTSSESEPEQPYFRSSCSNIPWREKEVPPKPHRPLCRSPCLDRPSFSQSSITQDLKLEECKTNLDKEYQAKMDFALKLGYAGDQIQAVLNKLGADALINDVLAELVRLGNKSESEGQNSASSTTSTLVPRGPCPKEIASPELSLEDEVVDNSDNLRPIVIDGSNVAMSHGNKEGFSCRGIQLAVDWFLEKGHKDITVFVPAWRKEQSRPDAPITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQNEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVIPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSAVKTMSEGALAKCGTGPSSSKGEISSEVKRIAPKRQSDPSIRSVAVEPEEKLTVARKSEANSVPSLVSALSVPTLPPPKSHAAGALNTRSASSPVPGSSQFTHQKSSLEHMSSVQYPPILVTNSHGTSISYTDQYPKYESLGDHGYYSLLSDFSNLSISSMHNTDYYGADMDQGMYSRNSSPCPDNCLSHTNNDSYSSYNDLYLGVADASPEDNVKIHRLTSQNRLQPFPHGYHEALNRVQSFGTEEPQQSLRKQSVSHLGLHAQHPVVGARSSCPGEYPVPQNIHPSTAQPSRALVMTRMDSISDSRLYESNPTRQRRPPLCREQHASWDPLPCASDSYTYHSYPLSNNLMQPCYEPVMVRSMPEKMEQLWRNPWIGICGEPREPHIIPEHQYQTYKNLCNIFPPSIVLSVMEKNPHMTDAQQLAAMIVAKLRTGR", "length": 837, "header": "tr|A0A1D5PB60-1|A0A1D5PB60_CHICK Isoform 1 of Zinc finger CCCH-type containing 12B OS=Gallus gallus OX=9031 GN=ZC3H12B PE=3 SV=1 CANONICAL=A0A1D5PB60-1" }, "locus": { "chromosome": "4", "start_pos": 52305, "end_pos": 44755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036184.1", "url": "https://www.ensembl.org/id/ENSGALT00010036184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021031.1", "url": "https://www.ensembl.org/id/ENSGALP00010021031.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422175", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422175", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACQ4-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTATAAVETPKMEKSASKEEKHQPKQKGSTDRDNADPEEWVNSESDPEPMSFKSGHNSNQSADIQLKKKEMPSKPHRPLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEAQVNLSLLLPRGASSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKIMSEDTLAKCGTGMSTAKGEITSEIKRVASKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMVSMQYPPILVTNSHGTPINYTEQYPKFETMGDHDYYSVLSDFSKLSINNMHNHEYYMAEANQGVYVRNPGLCTDSHMSHTRNDNYSSYNNLYLAVADAHPEGTLKLHRAASHNHLQPFSHGYHEALARVQSYGSEDSKQAPHKQSVPHLALHTQNPATGAHSSCPGDYTMPPNIHPVGPSQPGRALVMTRMDSISDSRLYDSNPMRQRRPPLCREQHASWDPLPCTADSYGYHSYPLGNSLMQPCYEPVMVRSMPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 835 }, "evidence": [ { "id": "A0A1D5PB60", "url": "https://omabrowser.org/oma/group/A0A1D5PB60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BN91-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQSKQENTEQGNADSEEWLGCESDPEQMSLKKSNSDNRCQLGDVQLNKKDILSKPHRQLCRSPCLDHPSFSQSSILHDGKLDLEKEYQTKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLNLLGPRGPSSREITSPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGDITSEVKRVTPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFEPLGDHSYYSVLGDFSKLNINSMHNREYYMAEADRGLYARNPNLCPDNRMSHTRNDNYSSYNNLYLAVADTHPEGSLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVSHLVLHAQHPTNGARSSCPGDYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYENNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWMNPWVGMCNDSREQMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAH", "length": 836 }, "evidence": [ { "id": "A0A1D5PB60", "url": "https://omabrowser.org/oma/group/A0A1D5PB60/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RTN0-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQPKQDSTEQGNADYEEWLSPETDTEHLNLKSRNNDNSCQLGDVQLKKKEIPSKPHRQLCRSPCLDHPSFSQSSILQDGKIDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLSVLMPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGEITSEVKRVAPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFESLGDHGYYSVLGDFSKLSINSMHNRDYYMAEADRGLYARNPSLCPDNRMSHTRNDNYSSYNNLYLAVADTHSEGNLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQAPHKQSVPHLVLHAQHPATGARSSCPGDYPMLPNVHPGATPQPGRALVMTRMDSISDSRLYESNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHVIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAR", "length": 836 }, "evidence": [ { "id": "A0A1D5PB60", "url": "https://omabrowser.org/oma/group/A0A1D5PB60/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X9I7-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTATAAVETPKMEKSASKEEKQQPKQEDSTDRGNADPEEWANSESDPEQMSCKSGHTSYQATDIQLKKKEMPSKPHRPLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEAQVNLSLLLPRGASSREIASPELSLEDEIDNSDNLRPIVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKIMSEDTLAKCGAGMSTAKGEITSEIKRVASKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMVSMQYPPILVTNSHGTPINYTEQYPKFETMGDHDYYSVLSDFSKLSINNMHNHEYYMAEANQGVYVRNPGLCTDSHMSHTRNDNYSSYNNLYLAVADAHPEGTLKLHRSASHNHLQPFSHGYHEALARVQSYGSEDSKQAPHKQSVPHLAVHTQNPATGAHSSCPGDYTMPPSIHPVGPSQPGRALVMTRMDSISDSRLYDSNPMRQRRPPLCREQHASWDPLPCTADSYGYHSYPLGNSLMQPCYEPVMVRSMPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 835 }, "evidence": [ { "id": "A0A1D5PB60", "url": "https://omabrowser.org/oma/group/A0A1D5PB60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5HYM0-1", "protein_name": "Probable ribonuclease ZC3H12B", "gene_name": "ZC3H12B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTATAEVETPKMEKSASKEEKQQPKQDSTEQGNADSEEWMSSESDPEQISLKSSDNSKSCQPRDGQLKKKEMHSKPHRQLCRSPCLDRPSFSQSSILQDGKLDLEKEYQAKMEFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEGQINLSLLVPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPIVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGMSSAKGEITSEVKRVAPKRQSDPSIRSVAMEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEHMASMQYPPILVTNSHGTPISYAEQYPKFESMGDHGYYSMLGDFSKLNINSMHNREYYMAEVDRGVYARNPNLCSDSRVSHTRNDNYSSYNNVYLAVADTHPEGNLKLHRSASQNRLQPFPHGYHEALTRVQSYGPEDSKQGPHKQSVPHLALHAQHPSTGTRSSCPADYPMPPNIHPGATPQPGRALVMTRMDSISDSRLYESNPVRQRRPPLCREQHASWDPLPCTTDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR", "length": 836 }, "evidence": [ { "id": "A0A1D5PB60", "url": "https://omabrowser.org/oma/group/A0A1D5PB60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB60", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PB60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 837, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PB60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PB60" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 579, "end_pos": 581 }, { "start_pos": 593, "end_pos": 595 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PBL9-1", "uniprot_ac": "A0A1D5PBL9", "uniprot_id": "A0A1D5PBL9_CHICK", "mass": { "chemical_mass": 68969.0, "monoisotopic_mass": 68969.0 }, "refseq": { "ac": "XP_015135322", "name": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135322" }, "gene_names": [ { "name": "LOC417113", "type": "recommended", "evidence": [ { "id": "A0A1D5PBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9" } ] }, { "name": "LOC417113", "type": "synonym", "evidence": [ { "id": "XP_015135322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135322" } ] } ], "protein_names": [ { "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9/entry#names_and_taxonomy" } ] }, { "name": "C-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9/entry#names_and_taxonomy" } ] }, { "name": "Nitric oxide synthase 1 adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9/entry#names_and_taxonomy" } ] }, { "name": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "synonym", "evidence": [ { "id": "XP_015135322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135322" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015135322.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135322" } ] }, { "annotation": "Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9#function" }, { "database": "UniProtKB", "id": "ARBA00054402", "url": "https://www.uniprot.org/uniprotkb/ARBA00054402#function" }, { "database": "UniProtKB", "id": "A0A8V1AD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD21#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC417113", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9", "locus": {} } ], "crossref": [ { "id": "A0A1D5PBL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041238", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01270", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01270", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417113", "url": "https://www.ncbi.nlm.nih.gov/gene/417113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417113", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDEKYKQ", "url": "https://omabrowser.org/oma/group/MDEKYKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBL9", "url": "https://www.orthodb.org/?gene=A0A1D5PBL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD21", "url": "https://www.orthodb.org/?gene=A0A8V1AD21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135322", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PBL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVKNRYNLVDDGCDSRVPLHNEEAFQHGIHFQAKYIGSLDVPRPSSRVEIVAAMRRIRYEFKAKNIKKKKVSIIVSVDGVKVILRKKQKRKEWTWDESKMVVMHDPVYRIFYVSHDSQDLKIFSYIARDGANNSFRCNVFKSKKKSQAMRVVRTVGQAFEVCHKLSLQHALQNADGQADGASDKSAEEQQSEVHQIKGSKITDVDEVGLDSDGICVSERGAGELPLARGELSTLKPGQGSKDKNCQDSESCSLYPAGSQQLLSPGSPCSSASITPLASQHCLQLLQQQLLQQQQQTQVAVAQVQLLKDQLAAETAARIEAQARVRQLLLTNRDLLQHVSLLVRQLKALESRAQRRQPVDRSLQNLSLAQSLSLNLKNHYSLDIALPSTSTPASVLGSPVAPRSLSALGAGDSYLNLVGLEGAGPCFGSKEGAEGLAAHEGLSRRVEGSEVGDFALLSGSGRQKAEDADRGDEDRRQQPIPKLNPPPPILRKRSSKTSPSLEVDIKPESTAHVSLPSPSVSGLTSITATSLTLLDPEARTPARSAAASAEPLPVGTFQRVLSKDRSGENGHTSPPSSIHDPAASDALSKDLAALLSPTDSTLPFSPADDTCLHISFSEDELLEPELDTTVGPSRVPS", "length": 637, "header": "tr|A0A1D5PBL9-1|A0A1D5PBL9_CHICK Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Gallus gallus OX=9031 GN=LOC417113 PE=4 SV=2 CANONICAL=A0A1D5PBL9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PBL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9/entry", "sequence": { "sequence": "MPVKNRYNLVDDGCDSRVPLHNEEAFQHGIHFQAKYIGSLDVPRPSSRVEIVAAMRRIRYEFKAKNIKKKKVSIIVSVDGVKVILRKKQKRKEWTWDESKMVVMHDPVYRIFYVSHDSQDLKIFSYIARDGANNSFRCNVFKSKKKSQAMRVVRTVGQAFEVCHKLSLQHALQNADGQADGASDKSAEEQQSEVHQIKGSKITDVDEVGLDSDGICVSERGAGELPLARGELSTLKPGQGSKDKNCQDSESCSLYPAGSQQLLSPGSPCSSASITPLASQHCLQLLQQQLLQQQQQTQVAVAQVQLLKDQLAAETAARIEAQARVRQLLLTNRDLLQHVSLLVRQLKALESRAQRRQPVDRSLQNLSLAQSLSLNLKNHYSLDIALPSTSTPASVLGSPVAPRSLSALGAGDSYLNLVGLEGAGPCFGSKEGAEGLAAHEGLSRRVEGSEVGDFALLSGSGRQKAEDADRGDEDRRQQPIPKLNPPPPILRKRSSKTSPSLEVDIKPESTAHVSLPSPSVSGLTSITATSLTLLDPEARTPARSAAASAEPLPVGTFQRVLSKDRSGENGHTSPPSSIHDPAASDALSKDLAALLSPTDSTLPFSPADDTCLHISFSEDELLEPELDTTVGPSRVPS", "length": 637, "header": "tr|A0A1D5PBL9-1|A0A1D5PBL9_CHICK Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Gallus gallus OX=9031 GN=LOC417113 PE=4 SV=2 CANONICAL=A0A1D5PBL9-1" }, "locus": { "chromosome": "17", "start_pos": 9298434, "end_pos": 9273648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067221.1", "url": "https://www.ensembl.org/id/ENSGALT00010067221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041125.1", "url": "https://www.ensembl.org/id/ENSGALP00010041125.1" } ] } }, { "isoform_ac": "A0A8V1AD21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD21/entry", "sequence": { "sequence": "MPVKNRYNLVDDGCDSRVPLHNEEAFQHGIHFQAKYIGSLDVPRPSSRVEIVAAMRRIRYEFKAKNIKKKKVSIIVSVDGVKVILRKKQKRKEWTWDESKMVVMHDPVYRIFYVSHDSQDLKIFSYIARDGANNSFRCNVFKSKKKSQAMRVVRTVGQAFEVCHKLSLQHALQNADGQADGASDKSAEEQQSEVHQIKGSKITDVDEVGLDSDGICVSERGAGELPLARGELSTLKPGQGSKDKNCQDSESCSLYPAGSQQLLSPGSPCSSASITPLASQHCLQLLQQQLLQQQQQTQVAVAQLTVRCRTCPWRSRCPST", "length": 320, "header": "tr|A0A8V1AD21-1|A0A1D5PBL9_CHICK Computationally mapped isoform of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Gallus gallus OX=9031 GN=LOC417113 PE=4 SV=1 CANONICAL=A0A1D5PBL9-1" }, "locus": { "chromosome": "17", "start_pos": 9297121, "end_pos": 9273648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067219.1", "url": "https://www.ensembl.org/id/ENSGALT00010067219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041123.1", "url": "https://www.ensembl.org/id/ENSGALP00010041123.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 391, "start_aa": "Thr", "end_pos": 391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr391", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417113", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBL9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PBL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 637, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PBL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBL9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBL9" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 165, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 391 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PBT5-1", "uniprot_ac": "A0A1D5PBT5", "uniprot_id": "A0A1D5PBT5_CHICK", "mass": { "chemical_mass": 7395.0, "monoisotopic_mass": 7395.0 }, "refseq": { "ac": "NP_001129044", "name": "protein BRAWNIN", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129044" }, "gene_names": [ { "name": "C12orf73", "type": "recommended", "evidence": [ { "id": "A0A1D5PBT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBT5" } ] }, { "name": "C12orf73", "type": "synonym", "evidence": [ { "id": "NP_001129044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129044" } ] }, { "name": "C1H12ORF73", "type": "synonym", "evidence": [ { "id": "NP_001129044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129044" } ] } ], "protein_names": [ { "name": "C12orf73 homolog", "type": "synonym", "evidence": [ { "id": "A0A1D5PBT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBT5/entry#names_and_taxonomy" } ] }, { "name": "protein BRAWNIN", "type": "synonym", "evidence": [ { "id": "NP_001129044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129044" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01024846.1, DR418905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Oct 2, 2008 this sequence version replaced XP_001234867.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001129044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBT5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf73", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBT5", "locus": { "chromosome": "1", "start_pos": 54755982, "end_pos": 54754288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010095", "url": "https://www.ensembl.org/id/ENSGALG00010010095" } ] } } ], "crossref": [ { "id": "A0A1D5PBT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030933", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030933", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "772057", "url": "https://www.ncbi.nlm.nih.gov/gene/772057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772057", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AVHRYYR", "url": "https://omabrowser.org/oma/group/AVHRYYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBT5", "url": "https://www.orthodb.org/?gene=A0A1D5PBT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28492", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28492", "database": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PBX6-1", "uniprot_ac": "A0A1D5PBX6", "uniprot_id": "A0A1D5PBX6_CHICK", "mass": { "chemical_mass": 10343.0, "monoisotopic_mass": 10343.0 }, "refseq": { "ac": "XP_040548162", "name": "feather keratin Cos1-1/Cos1-3/Cos2-1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548162" }, "gene_names": [ { "name": "LOC121112205", "type": "recommended", "evidence": [ { "id": "A0A1D5PBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6" } ] }, { "name": "LOC124417024", "type": "recommended", "evidence": [ { "id": "A0A1D5PBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6" } ] }, { "name": "LOC121112205", "type": "synonym", "evidence": [ { "id": "XP_040548162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548162" } ] }, { "name": "LOC124417024", "type": "synonym", "evidence": [ { "id": "A0A1D5PBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A1D5PBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6/entry#names_and_taxonomy" } ] }, { "name": "feather keratin Cos1-1/Cos1-3/Cos2-1-like", "type": "synonym", "evidence": [ { "id": "XP_040548162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548162" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052599.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040548162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548162" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121112205", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBX6", "locus": {} } ], "crossref": [ { "id": "121112205", "url": "https://www.ncbi.nlm.nih.gov/gene/121112205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"header": "tr|A0A1D5PBX6-1|A0A1D5PBX6_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121112205 PE=3 SV=1 CANONICAL=A0A1D5PBX6-1" }, "locus": { "chromosome": "27", "start_pos": 474168, "end_pos": 473866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062716.1", "url": "https://www.ensembl.org/id/ENSGALT00010062716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038768.1", "url": "https://www.ensembl.org/id/ENSGALP00010038768.1" } ] } }, { "isoform_ac": "A0A8V0ZYU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU7/entry", "sequence": { "sequence": "MSCCDQCVPCQPCGPTPLASSCNEPCVRQCQNSTIVIEPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSCQGVPITSGGFDLSCISNRYCGRRCTP", "length": 100, "header": "tr|A0A8V0ZYU7-1|A0A1D5PBX6_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC121112205 PE=3 SV=1 CANONICAL=A0A1D5PBX6-1" }, "locus": { "chromosome": "27", "start_pos": 474168, "end_pos": 473869, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062712.1", "url": "https://www.ensembl.org/id/ENSGALT00010062712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038766.1", "url": "https://www.ensembl.org/id/ENSGALP00010038766.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"uniprot_canonical_ac": "A0A1D5PBY7-1", "uniprot_ac": "A0A1D5PBY7", "uniprot_id": "A0A1D5PBY7_CHICK", "mass": { "chemical_mass": 42495.0, "monoisotopic_mass": 42495.0 }, "refseq": { "ac": "XP_024998134", "name": "protein NDRG3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998134" }, "gene_names": [ { "name": "LOC107057310", "type": "recommended", "evidence": [ { "id": "A0A1D5PBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7" } ] }, { "name": "LOC107057310", "type": "synonym", "evidence": [ { "id": "XP_024998134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998134" } ] } ], "protein_names": [ { "name": "NDRG family member 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7/entry#names_and_taxonomy" } ] }, { "name": "protein NDRG3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024998134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998134" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998134" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBY7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107057310", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7", "locus": {} } ], "crossref": [ { "id": "A0A1D5PBY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001492", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001492", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107057310", "url": "https://www.ncbi.nlm.nih.gov/gene/107057310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107057310", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107057310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITQYFAV", "url": "https://omabrowser.org/oma/group/ITQYFAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBY7", "url": "https://www.orthodb.org/?gene=A0A1D5PBY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024998134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998134", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PBY7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNAARNFQDFDCQEHDIETAFGVVHVTMRGIPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITHHFAVCHVDAPGQQEGAPPFPSGYQYPTMDELAEMLPAVLTHLNLKSFIGIGLGAGAYVLSRCALSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYIPYVQLSHLSTESVPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 387, "header": "tr|A0A1D5PBY7-1|A0A1D5PBY7_CHICK Isoform 1 of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=2 CANONICAL=A0A1D5PBY7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PBY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7/entry", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNAARNFQDFDCQEHDIETAFGVVHVTMRGIPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITHHFAVCHVDAPGQQEGAPPFPSGYQYPTMDELAEMLPAVLTHLNLKSFIGIGLGAGAYVLSRCALSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYIPYVQLSHLSTESVPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 387, "header": "tr|A0A1D5PBY7-1|A0A1D5PBY7_CHICK Isoform 1 of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=2 CANONICAL=A0A1D5PBY7-1" }, "locus": { "chromosome": "20", "start_pos": 1205075, "end_pos": 1175011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053047.1", "url": "https://www.ensembl.org/id/ENSGALT00010053047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031950.1", "url": "https://www.ensembl.org/id/ENSGALP00010031950.1" } ] } }, { "isoform_ac": "A0A8V0ZF65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF65/entry", "sequence": { "sequence": "MRGIPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITHHFAVCHVDAPGQQEGAPPFPSGYQYPTMDELAEMLPAVLTHLNLKSFIGIGLGAGAYVLSRCALSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYIPYVQLSHLSTESVPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 342, "header": "tr|A0A8V0ZF65-1|A0A8V0ZF65_CHICK Computationally mapped isoform of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=1 CANONICAL=A0A1D5PBY7-1" }, "locus": { "chromosome": "20", "start_pos": 1205075, "end_pos": 1193358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053029.1", "url": "https://www.ensembl.org/id/ENSGALT00010053029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031935.1", "url": "https://www.ensembl.org/id/ENSGALP00010031935.1" } ] } }, { "isoform_ac": "A0A8V0ZKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM5/entry", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNAARNFQDFDCQLSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYMPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 257, "header": "tr|A0A8V0ZKM5-1|A0A8V0ZKM5_CHICK Computationally mapped isoform of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=1 CANONICAL=A0A1D5PBY7-1" }, "locus": { "chromosome": "20", "start_pos": 1205075, "end_pos": 1175011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053042.1", "url": "https://www.ensembl.org/id/ENSGALT00010053042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031947.1", "url": "https://www.ensembl.org/id/ENSGALP00010031947.1" } ] } }, { "isoform_ac": "A0A8V0ZM92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM92/entry", "sequence": { "sequence": "MECKSGLSAGDNPETLQDMSGNVSTGLKAFNKANQFLFIRNREQSNLIVLLHKSTARPHLTLCQPLSLGRTECDGHQQCRQTDTAAPGRPYKLGNLSQEHDIETAFGVVHVTMRGIPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITHHFAVCHVDAPGQQEGAPPFPSGYQYPTMDELAEMLPAVLTHLNLKSFIGIGLGAGAYVLSRCALSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYMPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 441, "header": "tr|A0A8V0ZM92-1|A0A8V0ZM92_CHICK Computationally mapped isoform of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=1 CANONICAL=A0A1D5PBY7-1" }, "locus": { "chromosome": "20", "start_pos": 1205075, "end_pos": 1189425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053023.1", "url": "https://www.ensembl.org/id/ENSGALT00010053023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031929.1", "url": "https://www.ensembl.org/id/ENSGALP00010031929.1" } ] } }, { "isoform_ac": "A0A8V0ZT05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT05/entry", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKEHDIETAFGVVHVTMRGIPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITHHFAVCHVDAPGQQEGAPPFPSGYQYPTMDELAEMLPAVLTHLNLKSFIGIGLGAGAYVLSRCALSHPDLVEGLVLINVDPCAKGWIDWAASKFSGWTTNIVDIVLAHHFGHEELQANLDLIQTYRLHIAQDINQDNLQLFLTSYNSRRDLEIERPVIGVNENTAKTLKCPALLVVGDNSPAVEAVVECNSRLDPTKTTLLKMADCGGLPQVVQPGKLTEAFKYFVQGMGYIPYVQLSHLSTESVPAASMTRLMRSRTHSSSSVGSGESIRSRSHASNHGEGSAGTPDGIDLQDAPQTMEVSC", "length": 375, "header": "tr|A0A8V0ZT05-1|A0A1D5PBY7_CHICK Computationally mapped isoform of NDRG family member 3 OS=Gallus gallus OX=9031 GN=LOC107057310 PE=1 SV=1 CANONICAL=A0A1D5PBY7-1" }, "locus": { "chromosome": "20", "start_pos": 1205075, "end_pos": 1175011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053035.1", "url": "https://www.ensembl.org/id/ENSGALT00010053035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031941.1", "url": "https://www.ensembl.org/id/ENSGALP00010031941.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107057310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107057310", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYR2-1", "protein_name": "Protein NDRG3", "gene_name": "Ndrg3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "length": 375 }, "evidence": [ { "id": "A0A1D5PBY7", "url": "https://omabrowser.org/oma/group/A0A1D5PBY7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QYF9-1", "protein_name": "Protein NDRG3", "gene_name": "Ndrg3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGFTTNIVDIILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "length": 375 }, "evidence": [ { "id": "A0A1D5PBY7", "url": "https://omabrowser.org/oma/group/A0A1D5PBY7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGV2-1", "protein_name": "Protein NDRG3", "gene_name": "NDRG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC", "length": 375 }, "evidence": [ { "id": "A0A1D5PBY7", "url": "https://omabrowser.org/oma/group/A0A1D5PBY7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZUN1-1", "protein_name": "Protein NDL3", "gene_name": "NDL3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVGLNNAVSLDIEEICNGGKEHHVKTCHGSVSVVVYGDQEKPALITYPDVALNYMSCFQGLFLCPEAVSLLLHNFCIYHISPPGHEFGAAPVCSNDPSPSVEDLADQILEVLNFFSLEAVMCMGITAGAYILSLFAIKHKERVLGLILISPLCKAPSWSEWFYYKVVSNLLYYYGMSGLLKDIFLQRYFSKEARGSSEVPERDVVHECRRLLGERHGSSLMRFLEAVNRRHDLTDGLKSLKCRTLIFVGDQSPFHSETLHMVTALDRKYSALVEVQACGSMVTEEQPHAMLIPMEFFFMGFGLYRPGRVSDSPRSPLSPSCISPELLSPESLGLKLKPIKTRVPTKC", "length": 347 }, "evidence": [ { "id": "A0A1D5PBY7", "url": "https://omabrowser.org/oma/group/A0A1D5PBY7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBY7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBY7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PC10-1", "uniprot_ac": "A0A1D5PC10", "uniprot_id": "A0A1D5PC10_CHICK", "mass": { "chemical_mass": 58200.0, "monoisotopic_mass": 58200.0 }, "refseq": { "ac": "NP_001384378", "name": "suppressor of tumorigenicity 7 protein homolog isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" }, "gene_names": [ { "name": "ST7", "type": "recommended", "evidence": [ { "id": "A0A1D5PC10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10" } ] }, { "name": "ST7", "type": "synonym", "evidence": [ { "id": "NP_001384378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" } ] } ], "protein_names": [ { "name": "Suppression of tumorigenicity 7", "type": "synonym", "evidence": [ { "id": "A0A1D5PC10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10/entry#names_and_taxonomy" } ] }, { "name": "Suppressor of tumorigenicity protein 7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001384378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" } ] }, { "name": "suppressor of tumorigenicity 7 protein homolog isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001384378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" } ] }, { "name": "suppressor of tumorigenicity 7 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001384378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01087199.1, SRR13267655.140146.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Nov 16, 2021 this sequence version replaced XP_015136580.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PC10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10", "locus": { "chromosome": "1", "start_pos": 24877113, "end_pos": 24973223, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002280", "url": "https://www.ensembl.org/id/ENSGALG00010002280" } ] } } ], "crossref": [ { "id": "A0A1D5PC10", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PC10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037206", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417770", "url": "https://www.ncbi.nlm.nih.gov/gene/417770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PC10", "url": "https://www.orthodb.org/?gene=A0A1D5PC10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBU3", "url": "https://www.orthodb.org/?gene=A0A8V0XBU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PC10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PC10-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGTESSLSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNSAPSAANAANGEADSSRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDTDHLRPADAIMQKAWRERNPQARISAAHEALELNECATAYILLAEEEATTIVEAEKLFKQALKAGEGCYRRSQQLQHHGAQYEAQHRRDTNVLVYIKRRLAMCARKLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVESILPSSLWHQLTRI", "length": 511, "header": "tr|A0A1D5PC10-1|A0A1D5PC10_CHICK Isoform 1 of Suppression of tumorigenicity 7 OS=Gallus gallus OX=9031 GN=ST7 PE=3 SV=1 CANONICAL=A0A1D5PC10-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PC10-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10/entry", "sequence": { "sequence": "MFGTESSLSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNSAPSAANAANGEADSSRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDTDHLRPADAIMQKAWRERNPQARISAAHEALELNECATAYILLAEEEATTIVEAEKLFKQALKAGEGCYRRSQQLQHHGAQYEAQHRRDTNVLVYIKRRLAMCARKLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVESILPSSLWHQLTRI", "length": 511, "header": "tr|A0A1D5PC10-1|A0A1D5PC10_CHICK Isoform 1 of Suppression of tumorigenicity 7 OS=Gallus gallus OX=9031 GN=ST7 PE=3 SV=1 CANONICAL=A0A1D5PC10-1" }, "locus": { "chromosome": "1", "start_pos": 24972816, "end_pos": 24877341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005161.1", "url": "https://www.ensembl.org/id/ENSGALT00010005161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003035.1", "url": "https://www.ensembl.org/id/ENSGALP00010003035.1" } ] } }, { "isoform_ac": "A0A8V0XBU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU3/entry", "sequence": { "sequence": "MGRSVRSFPNLFYAFIRYLSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNSAPSAANAANGEADSSRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDTDHLRPADAIMQKAWRERNPQARISAAHEALELNECATAYILLAEEEATTIVEAEKLFKQALKAGEGCYRRSQQLQHHGAQYEAQHRRDTNVLVYIKRRLAMCARKLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAVGSQWPVAVVPLLFSPVS", "length": 509, "header": "tr|A0A8V0XBU3-1|A0A1D5PC10_CHICK Computationally mapped isoform of Suppression of tumorigenicity 7 OS=Gallus gallus OX=9031 GN=ST7 PE=3 SV=1 CANONICAL=A0A1D5PC10-1" }, "locus": { "chromosome": "1", "start_pos": 24936329, "end_pos": 24879190, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005159.1", "url": "https://www.ensembl.org/id/ENSGALT00010005159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003033.1", "url": "https://www.ensembl.org/id/ENSGALP00010003033.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PC10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PC10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PC10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 511, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PC10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PC10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PCF8-1", "uniprot_ac": "A0A1D5PCF8", "uniprot_id": "A0A1D5PCF8_CHICK", "mass": { "chemical_mass": 54134.0, "monoisotopic_mass": 54134.0 }, "refseq": { "ac": "XP_004940031", "name": "potassium voltage-gated channel subfamily S member 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940031" }, "gene_names": [ { "name": "KCNS2", "type": "recommended", "evidence": [ { "id": "A0A1D5PCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCF8" } ] }, { "name": "KCNS2", "type": "synonym", "evidence": [ { "id": "XP_004940031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940031" } ] } ], "protein_names": [ { "name": "Delayed-rectifier potassium channel regulatory subunit KCNS2", "type": "recommended", "evidence": [ { "id": "A0A1D5PCF8", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940031" } ] }, { "annotation": "Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCF8#function" }, { "database": "UniProtKB", "id": "ARBA00049573", "url": "https://www.uniprot.org/uniprotkb/ARBA00049573#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNS2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCF8", "locus": { "chromosome": "2", "start_pos": 127253917, "end_pos": 127177216, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011874", "url": "https://www.ensembl.org/id/ENSGALG00010011874" } ] } } ], "crossref": [ { "id": "ENSGALG00000043764", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043764", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18427", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18427", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430463", "url": "https://www.ncbi.nlm.nih.gov/gene/430463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PCM9-1", "uniprot_ac": "A0A1D5PCM9", "uniprot_id": "A0A1D5PCM9_CHICK", "mass": { "chemical_mass": 12562.0, "monoisotopic_mass": 12562.0 }, "refseq": { "ac": "NP_001264410", "name": "protein SNORC precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264410" }, "gene_names": [ { "name": "SNORC", "type": "recommended", "evidence": [ { "id": "A0A1D5PCM9", "database": "UniProtKB", "url": 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single sample supports all introns SAMEA103992290, SAMEA103992453 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU426473.1, BU432995.1 and CR353687.1. On Apr 11, 2013 this sequence version replaced XP_001231548.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264410", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264410" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNORC", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9", "locus": { "chromosome": "9", "start_pos": 688258, "end_pos": 681766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022826", "url": "https://www.ensembl.org/id/ENSGALG00010022826" } ] } } ], "crossref": [ { "id": "A0A1D5PCM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040264", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768774", "url": "https://www.ncbi.nlm.nih.gov/gene/768774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768774", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNEPIEL", "url": "https://omabrowser.org/oma/group/WNEPIEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PCM9", "url": "https://www.orthodb.org/?gene=A0A1D5PCM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28453:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28453:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264410", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PCM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCHRALRPLLLTLCFLLPAALAAEYPRGPLPTLWNEPAELPSGSGPFDAATTTARLSDGTAFAPYTSELEPEDTTHLHRLDAGDGSLGPGAIGAIVIASLLGTSVLVALVVITLRKFSAS", "length": 121, "header": "tr|A0A1D5PCM9-1|A0A1D5PCM9_CHICK Isoform 1 of Secondary ossification center associated regulator of chondrocyte maturation OS=Gallus gallus OX=9031 GN=SNORC PE=4 SV=1 CANONICAL=A0A1D5PCM9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9/entry", "sequence": { "sequence": "MPCHRALRPLLLTLCFLLPAALAAEYPRGPLPTLWNEPAELPSGSGPFDAATTTARLSDGTAFAPYTSELEPEDTTHLHRLDAGDGSLGPGAIGAIVIASLLGTSVLVALVVITLRKFSAS", "length": 121, "header": "tr|A0A1D5PCM9-1|A0A1D5PCM9_CHICK Isoform 1 of Secondary ossification center associated regulator of chondrocyte maturation OS=Gallus gallus OX=9031 GN=SNORC PE=4 SV=1 CANONICAL=A0A1D5PCM9-1" }, "locus": { "chromosome": "9", "start_pos": 688235, "end_pos": 681965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055516.1", "url": "https://www.ensembl.org/id/ENSGALT00010055516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033632.1", "url": "https://www.ensembl.org/id/ENSGALP00010033632.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768774", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SM49-1", "protein_name": "Secondary ossification center associated regulator of chondrocyte maturation", "gene_name": "SNORC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFRLALRVALLLLSGVLAPAVLTAEGPQEPEPTLWNEPAELPSGEGPAESTSPAREPAATAPPAPTAAPSPEDSTARERLDQGGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "length": 121 }, "evidence": [ { "id": "A0A1D5PCM9", "url": "https://omabrowser.org/oma/group/A0A1D5PCM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6UX34-1", "protein_name": "Protein SNORC", "gene_name": "SNORC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCLALRMALLLVSGVLAPAVLTDDVPQEPVPTLWNEPAELPSGEGPVESTSPGREPVDTGPPAPTVAPGPEDSTAQERLDQGGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "length": 121 }, "evidence": [ { "id": "A0A1D5PCM9", "url": "https://omabrowser.org/oma/group/A0A1D5PCM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXL7-1", "protein_name": "Protein SNORC", "gene_name": "Snorc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCLALRVALLLISGVLAPAVLTAEGPQEPDPTLWNEPIELPSGEGPLESTSHNQEFAVSGPPFPTSAPAPEDSTPPARVDQDGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS", "length": 121 }, "evidence": [ { "id": "A0A1D5PCM9", "url": "https://omabrowser.org/oma/group/A0A1D5PCM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PCM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PCM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 121, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PCM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCM9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PDC2-1", "uniprot_ac": "A0A1D5PDC2", "uniprot_id": "A0A1D5PDC2_CHICK", "mass": { "chemical_mass": 30558.0, "monoisotopic_mass": 30558.0 }, "refseq": { "ac": "XP_418311", "name": "AN1-type zinc finger protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418311" }, "gene_names": [ { "name": "ZFAND1", "type": "recommended", "evidence": [ { "id": "A0A1D5PDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ] }, { "name": "ZFAND1", "type": "synonym", "evidence": [ { "id": "XP_418311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418311" } ] } ], "protein_names": [ { "name": "AN1-type zinc finger protein 1", "type": "synonym", "evidence": [ { "id": "XP_418311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418311" } ] }, { "name": "Zinc finger AN1-type containing 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418311.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418311" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFAND1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2", "locus": { "chromosome": "2", "start_pos": 121087651, "end_pos": 121096773, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003344", "url": "https://www.ensembl.org/id/ENSGALG00010003344" } ] } } ], "crossref": [ { "id": "A0A1D5PDC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDC2", "database": "AlphaFoldDB", "categories": [] }, { "id": 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Classification" ] }, { "id": "A0A1D5PDC2", "url": "https://www.orthodb.org/?gene=A0A1D5PDC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9B0", "url": "https://www.orthodb.org/?gene=A0A8V0X9B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14677:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14677:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418311", "url": 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"tr|A0A1D5PDC2-1|A0A1D5PDC2_CHICK Isoform 1 of Zinc finger AN1-type containing 1 OS=Gallus gallus OX=9031 GN=ZFAND1 PE=1 SV=1 CANONICAL=A0A1D5PDC2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2/entry", "sequence": { "sequence": "MAELLLGQHCGVPDCRQLDFLPFVCDGCSGVFCLQHRSRDAHGCSEVNIRNNSVKPDQHRSYLCSYKDCQAKELLPVLCPYCEKHFCLRHRHQSDHECEKLDTPKPRMAATQQLVKDIIDSKKNEDIKSKKRKGARNSETAAKVALMKLKMHACGDKSLPQAERIYFQVLLPKGNKEKSKPMFFCSKWSIGKVVDYAASLASLKNDNNKSTAQKLRLCHSASGEALPFEHTLEKWLSDEDYPLFNGGNIILEYLDNDVLFIEDTESYLS", "length": 269, "header": "tr|A0A1D5PDC2-1|A0A1D5PDC2_CHICK Isoform 1 of Zinc finger AN1-type containing 1 OS=Gallus gallus OX=9031 GN=ZFAND1 PE=1 SV=1 CANONICAL=A0A1D5PDC2-1" }, "locus": { "chromosome": "2", "start_pos": 121096760, "end_pos": 121091283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007816.1", "url": "https://www.ensembl.org/id/ENSGALT00010007816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004692.1", "url": "https://www.ensembl.org/id/ENSGALP00010004692.1" } ] } }, { "isoform_ac": "A0A8V0X9B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9B0/entry", "sequence": { "sequence": "MAELLLGQHCGVPDCRQLDFLPFVCDGCSGVFCLQHRSRDAHGCSEVNIRNNSVKPDQHRSYLCSYKDCQAKELLPVLCPYCEKHFCLRHRHQSDHECEKLDTPKPRMAATQQLVKDIIDSKKNEDIKSKKRKGARNSETAAKVALMKLKMHACGDKSLPQ", "length": 161, "header": "tr|A0A8V0X9B0-1|A0A1D5PDC2_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 1 OS=Gallus gallus OX=9031 GN=ZFAND1 PE=1 SV=1 CANONICAL=A0A1D5PDC2-1" }, "locus": { "chromosome": "2", "start_pos": 121096760, "end_pos": 121093434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007814.1", "url": "https://www.ensembl.org/id/ENSGALT00010007814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004689.1", "url": "https://www.ensembl.org/id/ENSGALP00010004689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420200", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480TK05-1", "protein_name": "Zinc finger AN1-type containing 1", "gene_name": "ZFAND1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAELDIGQHCQVEHCRQRDFLPFVCDGCSGIFCLEHRSRESHSCPEVTVTSERLKSDTHTSYPCSFKECAERELVPVVCPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIIDSKTGETASKRRKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKPMFFCQRWSIGKVIDFAASLASLKNDNNKLTAKKLRLCHITSGEALPLDHILETWIAKEDCPLYNGGNVILEYLNDEEQFLKNVDSYLE", "length": 268 }, "evidence": [ { "id": "A0A1D5PDC2", "url": "https://omabrowser.org/oma/group/A0A1D5PDC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53899-1", "protein_name": "CDC48-associated ubiquitin-like/zinc finger protein 1", "gene_name": "CUZ1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSAAIEKETGMLDVGKHCAYCRQLDFLPFHCSFCNEDFCSNHRLKEDHHCRWLLEHEEVHKTEKSPSKSRDGSSSNDEAYFKSLLPERASVRIQRVSETREPLRGSNTAKVSSTLNSKTLDKIFKFFQRNEKRKSNNKSKKNFGSSSNKIIQLANLKKIAKGDPKIPMQNRIYIWCYLVDGDETDIAKEDTRMPLYINKMWPVGRAMDYLSIQLNVKSSTLTNSSSNDKFQLCKLKEGKQVSFYNIGASLRVTNEIKDLDTLYLVHNNADEKSN", "length": 274 }, "evidence": [ { "id": "A0A1D5PDC2", "url": "https://omabrowser.org/oma/group/A0A1D5PDC2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8BFR6-1", "protein_name": "AN1-type zinc finger protein 1", "gene_name": "Zfand1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELDIGQHCQVQHCRQRDFLPFVCDGCSGIFCLEHRSKDSHGCSEVNVVKERPKTDEHKSYSCSFKGCTDVELVAVICPYCEKNFCLRHRHQSDHDCEKLEVAKPRMAATQKLVRDIVDAKTGGAASKGRKGAKSSGTAAKVALMKLKMHADGDKSLPQTERTYFQVYLPKGSKEKSKAMFFCLRWSIGKVVDFAASLANLRNENNKLTAKKLRLCHVPSGEALPLDHTLERWITKEECPLYNGGNVILEYLNDEEQFLKNVDSYLE", "length": 268 }, "evidence": [ { "id": "A0A1D5PDC2", "url": "https://omabrowser.org/oma/group/A0A1D5PDC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCF1-1", "protein_name": "AN1-type zinc finger protein 1", "gene_name": "ZFAND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELDIGQHCQVEHCRQRDFLPFVCDDCSGIFCLEHRSRESHGCPEVTVINERLKTDQHTSYPCSFKDCAERELVAVICPYCEKNFCLRHRHQSDHECEKLEIPKPRMAATQKLVKDIIDSKTGETASKRWKGAKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKEKSKPMFFCHRWSIGKAIDFAASLARLKNDNNKFTAKKLRLCHITSGEALPLDHTLETWIAKEDCPLYNGGNIILEYLNDEEQFCKNVESYLE", "length": 268 }, "evidence": [ { "id": "A0A1D5PDC2", "url": "https://omabrowser.org/oma/group/A0A1D5PDC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" }, { "name": "stress granule disassembly", "id": "GO:0035617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035617", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" }, { "name": "cellular response to arsenite ion", "id": "GO:1903843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903843", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": 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"isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PDL4-1", "uniprot_ac": "A0A1D5PDL4", "uniprot_id": "A0A1D5PDL4_CHICK", "mass": { "chemical_mass": 125016.0, "monoisotopic_mass": 125016.0 }, "refseq": { "ac": "XP_015143411", "name": "WD repeat and HMG-box DNA-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143411" }, "gene_names": [ { "name": "WDHD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PDL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ] }, { "name": "WDHD1", "type": "synonym", "evidence": [ { "id": "XP_015143411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143411" } ] } ], "protein_names": [ { "name": "WD repeat and HMG-box DNA-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PDL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4/entry#names_and_taxonomy" } ] }, { "name": "Acidic nucleoplasmic DNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PDL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4/entry#names_and_taxonomy" } ] }, { "name": "WD repeat and HMG-box DNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "XP_015143411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143411" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143411" } ] }, { "annotation": "Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4#function" }, { "database": "UniProtKB", "id": "ARBA00056293", "url": "https://www.uniprot.org/uniprotkb/ARBA00056293#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDHD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4", "locus": { "chromosome": "5", "start_pos": 55982546, "end_pos": 55901925, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018780", "url": "https://www.ensembl.org/id/ENSGALG00010018780" } ] } } ], "crossref": [ { "id": "A0A1D5PDL4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012199", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012199", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21993", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21993", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423558", "url": "https://www.ncbi.nlm.nih.gov/gene/423558", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423558", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423558", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYAHTNG", "url": "https://omabrowser.org/oma/group/RYAHTNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDL4", "url": "https://www.orthodb.org/?gene=A0A1D5PDL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19932:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19932:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143411", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEQKPMRYGHTEGHTDVCFDDSGSCIVTCGSDGDVRIWENLDDDDPKSINVGEKAYSCALKNGKLITAVSNNTVQIHTFPEGAPDGILTRFTMNANHVVFNSDGAKIAAGSSDFMVKVVEVADSSKQKTFRGHDAPVLSLSFDPMDIYLASASCDGSVRVWKVEDQTCVTNWLLLQKCNDVINAKSICRLAWQPGSGKLLAIPVDKVVKLYRRETWDNQVDLSDTSITQPLNVVVWSPCGQYLAAGSVNGSIVVWKVETRECTERMKHEKSYSICGLAWHPRYEQIAYTDTEGNLGLWEDIGDGKKPNDKVASTVTKDYEDLFDGDDDDYLNGDMIEPPSSPNTGANEDHGDDDDLMPTSGHPRRAIIDDDDNSLDIGMIKANSNLLEKEEDDDDQIGGFPALPTSSTQQPFYDGPRPTPRQKPFQSGSTPVHLMHRFMVWNSVGIIRCYNDEQDNAIDIEFHDTSIHHATHLPNSLNHTMADLSTEAILLACESTEELASKLHCIYFSSWDANKEWTVDMPKDEDIEAICLGQGWAACATSALLVRLFTVGGVQKEIFCLPGPVVSMAGHGEQLMVIYHRGTGFDGDQCLGVQLMELGKKKKQILHGDPLSLTKKSYLVWVGFSAEGTPCYVDSEGIVRMLNRGLGNTWIPVCNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGARFPPTLPRPAVAILPFTLPYCQVTTEKGQMEEQYWRSVVFHNYVDYLSKNGYELDENAKSQPVKEQQELLMKLFALSCKLEREFRCVELADLMTQNVVNLAIKYASRSRRLNLAQRLSEMAVEKASELATALEDEEEEEEEDFRTHLNAGYSTSATEWGRLPGRSAQQDQEMEEAEETNGYEEAEGTPEVPKQRPNPFSKAVSSAEVITPKSAVIASSSQGRVNPFKVSSNKKDPLVPSSNVLDTMSKYSKKISSSRAVNKQSSPVIKPLIPKPKSKQASAASFFQVRTPGSSEKRVGEREEKAGHEPPEVQVTAQDNTENKRPKTGFQMWLEENRANILTDNPDLNEAEVIKEGMSRFRILSSEERMVWTEKAKGGAVTDLTEDKKRKRPTAAEDEAKKNEEQKSEDSNVSKKKKPLDQATNVRLSSFAFKQS", "length": 1123, "header": "tr|A0A1D5PDL4-1|A0A1D5PDL4_CHICK Isoform 1 of WD repeat and HMG-box DNA-binding protein 1 OS=Gallus gallus OX=9031 GN=WDHD1 PE=4 SV=3 CANONICAL=A0A1D5PDL4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4/entry", "sequence": { "sequence": "MPSEQKPMRYGHTEGHTDVCFDDSGSCIVTCGSDGDVRIWENLDDDDPKSINVGEKAYSCALKNGKLITAVSNNTVQIHTFPEGAPDGILTRFTMNANHVVFNSDGAKIAAGSSDFMVKVVEVADSSKQKTFRGHDAPVLSLSFDPMDIYLASASCDGSVRVWKVEDQTCVTNWLLLQKCNDVINAKSICRLAWQPGSGKLLAIPVDKVVKLYRRETWDNQVDLSDTSITQPLNVVVWSPCGQYLAAGSVNGSIVVWKVETRECTERMKHEKSYSICGLAWHPRYEQIAYTDTEGNLGLWEDIGDGKKPNDKVASTVTKDYEDLFDGDDDDYLNGDMIEPPSSPNTGANEDHGDDDDLMPTSGHPRRAIIDDDDNSLDIGMIKANSNLLEKEEDDDDQIGGFPALPTSSTQQPFYDGPRPTPRQKPFQSGSTPVHLMHRFMVWNSVGIIRCYNDEQDNAIDIEFHDTSIHHATHLPNSLNHTMADLSTEAILLACESTEELASKLHCIYFSSWDANKEWTVDMPKDEDIEAICLGQGWAACATSALLVRLFTVGGVQKEIFCLPGPVVSMAGHGEQLMVIYHRGTGFDGDQCLGVQLMELGKKKKQILHGDPLSLTKKSYLVWVGFSAEGTPCYVDSEGIVRMLNRGLGNTWIPVCNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGARFPPTLPRPAVAILPFTLPYCQVTTEKGQMEEQYWRSVVFHNYVDYLSKNGYELDENAKSQPVKEQQELLMKLFALSCKLEREFRCVELADLMTQNVVNLAIKYASRSRRLNLAQRLSEMAVEKASELATALEDEEEEEEEDFRTHLNAGYSTSATEWGRLPGRSAQQDQEMEEAEETNGYEEAEGTPEVPKQRPNPFSKAVSSAEVITPKSAVIASSSQGRVNPFKVSSNKKDPLVPSSNVLDTMSKYSKKISSSRAVNKQSSPVIKPLIPKPKSKQASAASFFQVRTPGSSEKRVGEREEKAGHEPPEVQVTAQDNTENKRPKTGFQMWLEENRANILTDNPDLNEAEVIKEGMSRFRILSSEERMVWTEKAKGGAVTDLTEDKKRKRPTAAEDEAKKNEEQKSEDSNVSKKKKPLDQATNVRLSSFAFKQS", "length": 1123, "header": "tr|A0A1D5PDL4-1|A0A1D5PDL4_CHICK Isoform 1 of WD repeat and HMG-box DNA-binding protein 1 OS=Gallus gallus OX=9031 GN=WDHD1 PE=4 SV=3 CANONICAL=A0A1D5PDL4-1" }, "locus": { "chromosome": "5", "start_pos": 55931714, "end_pos": 55902298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045379.1", "url": "https://www.ensembl.org/id/ENSGALT00010045379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027087.1", "url": "https://www.ensembl.org/id/ENSGALP00010027087.1" } ] } }, { "isoform_ac": "A0A8V0ZEU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU8/entry", "sequence": { "sequence": "MPSEQKPMRYGHTEGHTDVCFDDSGSCIVTCGSDGDVRIWENLDDDDPKSINVGEKAYSCALKNGKLITAVSNNTVQIHTFPEGAPDGILTRFTMNANHVVFNNDDDYLNGDMIEPPSSPNTGANEDHGDDDDLMPTSGHPRRAIIDDDDNSLDIGMIKANSNLLEKEEDDDDQIGGFPALPTSSTQQPFYDGPRPTPRQKPFQSGSTPVHLMHRFMVWNSVGIIRCYNDEQDNAIDIEFHDTSIHHATHLPNSLNHTMADLSTEAILLACESTEELASKLHCIYFSSWDANKEWTVDMPKDEDIEAICLGQGWAACATSALLVRLFTVGGVQKEIFCLPGPVVSMAGHGEQLMVIYHRGTGFDGDQCLGVQLMELGKKKKQILHGDPLSLTKKSYLVWVGFSAEGTPCYVDSEGIVRMLNRGLGNTWIPVCNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGARFPPTLPRPAVAILPFTLPYCQVTTEKGQMEEQYWRSVVFHNYVDYLSKNGYELDENAKSQPVKEQQELLMKLFALSCKLEREFRCVELADLMTQNVVNLAIKYASRSRRLNLAQRLSEMAVEKASELATALEDEEEEEEEDFRTHLNAGYSTSATEWGRLPGRSAQQDQEMEEAEETNGYEEAEGTPEVPKQRPNPFSKAVSSAEVITPKSAVIASSSQGRVNPFKVSSNKKDPLVPSSNVLDTMSKYSKKISSSRAVNKQSSPVIKPLIPKPKSKQASAASFFQVRTPGSSEKRVGEREEKAGHEPPEVQVTAQDNTENKRPKTGFQMWLEENRANILTDNPDLNEAEVIKEGMSRFRILSSEERMVWTEKAKGGAVTDLTEDKKRKRPTAAEDEAKKNEEQKSEDSNVSKKKKPLDQATNVRLSSFAFKQS", "length": 899, "header": "tr|A0A8V0ZEU8-1|A0A8V0ZEU8_CHICK Computationally mapped isoform of WD repeat and HMG-box DNA-binding protein 1 OS=Gallus gallus OX=9031 GN=WDHD1 PE=4 SV=1 CANONICAL=A0A1D5PDL4-1" }, "locus": { "chromosome": "5", "start_pos": 55931714, "end_pos": 55902298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045372.1", "url": "https://www.ensembl.org/id/ENSGALT00010045372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027084.1", "url": "https://www.ensembl.org/id/ENSGALP00010027084.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 421, "start_aa": "Thr", "end_pos": 421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr421", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423558", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423558", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZN63-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "Wdhd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAIQKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRMWEDLDDDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGAPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDVFLASASCDGTVRVWNISDQTCAASWPVLRKSNDVVNSESICRLAWQPKTGKFLAVPVEKSVKLYRRETWSNPFDLSDSSVTQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKECMERVKHEKGYAICGLAWHPTYSRICYTDVEGNLGILENVCDLSGKLSSNKVPSGVEKDYSDLFDGDDTSSAGDFLNDNAVEIPSFSKGIRNEEDDNDDLMLAADHVLGDDENSVDVTMLRNDLHREEGEDRQASSLHSLPLVKSQRPLYDGPMPTPRQKPFQPSSTPLHLTHRFMAWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLSNAFNYTMGSLSHEAVLLACESADELASKLHCLHFSSWDSSKEWIVDMPENEDIEAICLGLGWAAAATSALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRKKKQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILPFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAENGYDYEESIKKQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAEIQTEEREEDFRERLNAGYSHTTTEWSQPRVRSQVEEDAEDREDTVSEGNPEPQNHVIGQNLIQSANSSDTPAMKSGAVFSSSQGRVNPFKVLVSSKEPAVSVNATRSANILDNMNKLSRKSTSFNRVANNEKSPVIKPLIPKPRCKQASAASYFQKRTSQAEKTEEVKENPKSSSSEAPAVCLQNSEVQRPKTGFQMWLEENRSHIMSDNPDISDEADIIKEGMIRFRVLSAEERKEWTNKAKGGTASDGAEAKKRKRGVSEICETEKQEEAVKENLELSKKQKALDLSTNQKLSAFAFKQE", "length": 1119 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7F5-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPATQKPMRYGHTEGHTDVCFDDSGSCIVTCGSDGDVRIWEDLDDDDPKSINVGEKAYSCALKNGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDCSQQKTFRGHDAPVLSLSFDPKDIFLASSSCDGSVKVWQISDQTCPISWPLLQKCNDVVNAKSICRLAWQPKSGKLLAVPVEKSVKLYKRETWSNQFDLSDDVISQTLNIVTWSPCGQYLAAGSINGLIIIWNVETKNCIERVKHEKGYAICGLSWHPTCGQIAYTDAEGNLGLLENVCDPSGKMSNRKVSSRVEKDYNDLFDGDDTSNVGDCLNDSAVKTHSFSKGIVNDEEDDDDLMLASGRPRQRSHILEDDENSVDVTMLKIGSSLFKEEEDDQGGSIHNLPVVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLLNTFNYTVADLSHEAVLLACESTDELASKLHCLHLSSWDSSKEWIVDMPPNEDIEAICLGQGWAAAATSSLLLRLFTIGGVQKEVFSLPGPIVSMAGHGEQLVIVYHRGTGFDGDQCLGVQLLELGKKKKQILHGDPLPLTRKSYLVWVGFSAEGTPCYVDSEGIVRMLNRGLGHTWTPVCNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAVLSFKLPYCQTATEKGQMEEQYWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLLKMLALSCKLEREFRCVELAGLMTQNAVNLAIKYASRSRRLILAQRLGELAVEKAAELAATQAEEEEEEDFRKKLNVGYSNTSTEWSQPRLRNQVEEDTEDNGEADNTEENTEIHKHGQNPFFKSADSSDMPALKSGAVTSSSQGRINPFKVSGNSKEPAISVSSGRSTNILDTMNKSSKKSTALNRATDNEKSPVIKPLIPKPKPKQASAASFFQKRTSQADRTEEVKEENPKNSSSETPAVCPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMVRFKVLSSEERKAWAARAKGGTASDGAEEKKRKRVVDESQETENQEEKMKNLNLPKKQKPLDLSTNQKLSAFAFKQE", "length": 1127 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SSP1-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPATQKPMRYGHTEGHTDVCFDDSGSCIVTCGSDGDVRIWEDLDDDDPKSINVGEKAYSCALKNGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVIFNEDGTKIAAGSSDFLVKVVDVMDCSQQKTFRGHDAPVLSLSFDPKDIFLASSSCDGSVKVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKSGKLLAVPVEKSVKLYRRETWSNQFDLSDNFISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLSWHPTCGQIAYTDAEGNLGLLENVCDPNGKMSGSKVSSRVERDYNDLFDGDDTGNVGDFPNDNAVETHSFSKETRNDEEDDDDLMLASGRPRQRSHILEDDENSVDVTMLKTGSSRLKEEEEDDQAGNIHSLPLITSQKPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTVADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIVDMPPNEDIEAVCLGQGWAAAATSSLLLRLFTIGGVQKEVFSLPGPVVSMAGHGEQLIIVYHRGTGFDGDQCLGIQLLQLGKKKKQILHGDPLPLTRKSYLVWLGFSAEGTPCYVDSEGIVRMLNRGLGYTWTPICNTREHCKGKSDHYWVVGIHENPQHLRCIPCKGSRFPPTLPRPAIAVLSFKLPYCQTGTEKGQMEEQYWRSVLFHNHLDYLAKSGYEYEESTKNQAIKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRRLILAQKLSELAVEKAAELAAPQAEEEEEEEEDFRKKLNAGYSNTPTEWSQPRLRNRVEEDTEDTEEVDDIEEKPEIHKHRQNPFFKSADSTDVPAIKSGAVTSSSQGRINPFKVSGSSKEPANSFSSVRSTNILDNMNKSKKSALNRATNNEKSPVIKPLVPKPKSKQASAASFFQKRTSQTDKTEEIKEENTKNSSSETPAVCPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMVRFRVLSAEERKAWAAKAKGGIASDGAEEKKRKRVVDESHETENQEEKTKENLNLPKKQKPLNLSANQKLSAFAFKQE", "length": 1129 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JF14-1", "protein_name": "Protein ENHANCER OF LHP1 1", "gene_name": "EOL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKSRSLKLREAHKVGGSAAFCSILWDHKAEHFVTSSSSDPSISVHDGLSTSTLPPTILRHHQDGVTSLALSNDSTLLASGSIDHCVKLYKFPSGEFQTNITRFTLPIRVLAFNGSGSLLAAAGDDEGIKLINTFDGSIVRVLKGHKGPVTGLDFHPNGELLASIDTTGTVLCWELQNGVVSFTLKGVAPDTGFNTSIVNIPRWSPDGRTLAVPGLRNDVVMYDRFTGEKLFALRGDHLEAICYLTWAPNGKYIATSGLDKQVLLWDVDKKQDIDRHKFEERICCMSWKPNGNALSVIDAKGRYGVWESLVPSSMLSPTVGVPDIVPKKRNEILDFDDEVEEEIYRASESLDDAMGDSDDGESHHTSRKRLRKKTLIDEDVDDAYEELNDGSSLPSASEYRKKSHRGHREKQGARSGAFKGISASTKYKMQSSFQPGATPPEPGKRTFLCYNMLGCITTIEHEGNSRIETDFHDTGRGPRVSSMIDIYGFTMASINETGCVFANPCKGEKNMSVLMYRPFRSWASNSEWTMRFEGEEVKVVANGSGWVAAVTSLNLLRVFSEGGLQKHILSLDGPVVTAVGCKDHLAVVTHVSDCLPSNEQVMEFRVFNISKMTQELKGRVALTPGSRLTWIGFSEEGSLSSYDSEGVLRVFTSQYGGSWIPVFSTSKEKKQEENYWVVGLNTSSLYCIACKYAEMFPQVTPKPILTILDLSLPLASSDLGAASLENELILKQLRLYETQRKVDDMALVGVDTTALEDEAFDLEVSQDKCILRLISSCCSSDSFARASELMELLTLEKSMRAAITLVTKLKLPFLAEKFSSILEERLLEEASEAAVTNPALNPNGEVVTRVESKVQNPPASIQTSENTEAVMKSSATKLSAPTLLKKSKVSEGLKLGKEQTKKDKSDDAKIKEIKKLNLKNPVNNVNKEDKGQEKEVNQGEARRSSNPFLKSTV", "length": 953 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O75717-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLDDDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESWSHQFDLSDNFISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLAWHPTCGRISYTDAEGNLGLLENVCDPSGKTSSSKVSSRVEKDYNDLFDGDDMSNAGDFLNDNAVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTGSSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEVFSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKKKKQILHGDPLPLTRKSYLAWIGFSAEGTPCYVDSEGIVRMLNRGLGNTWTPICNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQIATEKGQMEEQFWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRKLILAQKLSELAVEKAAELTATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDSGEADDEEKPEIHKPGQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEENLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE", "length": 1129 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59328-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "Wdhd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPATQKPMRYGHTEGHTEVCFDDSGSYIVTCGSDGDVRMWEDLDDDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGVPDGILTRFTTNANHVVFNGAGNKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNISDQTCAVSWPVLQKSNDVVNAKSICRLAWQPKAGKLLAVPVEKSVKLYRRETWSNPFDLSDSSISQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKDCMERVKHEKGYAICGLAWHPTCSRICYTDVEGNLGVLENVCDLSGKVSSNKVSSRVEKDYNDLFDGDDTSSAGDFLNDNAVEIPSFSKGIINEDDDNDDIMLAADHDLGDDENSVDVTMLKADLSHKEEGDDDQARSIHNLPLIRPQRPFYDGPMPTPRQKPFQSSSTPLHLSHRFMVWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLLNAFNYTMGTLSHEAILLACESADELASKLHCLHFSSWDSSKEWMVDMPQNEDIEAICLGLGWAAAATTALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRKKNQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAKNGYDYEESIKNQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAETQSEEEKEEDFREKLNAGYSHTTTEWSRPRVRSQVEDAEDREDTVSEEKPESHNHGQNLFQSANSSDTPALKSGAVFSSSQGWVNPFKVVVSSKEPAVSANSTRSANILDSMNKSSRKSTSLNRMENNEKSPVIKPLTPKPRSKQASAASYFQKRTPQADKTEEVKENPKSSSSDAPAVCLQNSENQRPKTGFQMWLEENRSQILSDNPDISDETDIIKEGMIRFRVLSAEERKAWTNKAKGETASDGAEAKKRKRVVSEICETENQEETVKENLDLSKKQKALNLPANQKLSAFAFKQ", "length": 1117 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01454-1", "protein_name": "DNA polymerase alpha-binding protein", "gene_name": "CTF4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSVIDKLVFDFGGKTLVSLAPDNNTLCVANKNGLTKILKTNNPEEEPETLDSSKLVSSIKCYSNSHFLMTTMQGDALRYNIDSSQEELLARFALPLRDCCVIHSGKMAVFGGDDLELILLELDDETHKKHAIKIDEQVSQISYNSQMNILAVSMINGKVQIFSLTSTIPNKVHELNDYIVANSYDDTHRDKILSNMMDDIDKDNDNDLSETADPDENNVADPEFCAANRICTRVAWHPKGLHFALPCADDTVKIFSIKGYSLQKTLSTNLSSTKAHFIDLQFDPLRGTYIAAVDLNNKLTVWNWETSEIHYTREFKRKITNIAWKIQADSKTLDLVLGTWSGSIAIVQNLAESVVSNIPDQSVAESSTKHGLFVDSESDLENLEGNDDINKSDKLFSDITQEANAEDVFTQTHDGPSGLSEKRKYNFEDEEDFIDDDDGAGYISGKKPHNEHSYSRVHKTHSFPISLANTGKFRYMPFSPAGTPFGFTDRRYLTMNEVGYVSTVKNSEQYSITVSFFDVGRFREYHFEDLFGYDLCFLNEKGTLFGQSKTGQIQYRPHDSIHSNWTKIIPLQAGERITSVAATPVRVIVGTSLGYFRSFNQFGVPFAVEKTSPIVALTAQNYRVFSVHYSQFHGLSYSLSELGTSSKRYYKRECPLPMSLPNINSDMKKDANLDYYNFNPMGIKSLFFSSYGDPCIFGSDNTLLLLSKWRSPEESKWLPILDSNMEIWKMSGGKETTDIHVWPLALAYDTLNCILVKGKHIWPEFPLPLPSEMEIRMPVFVKSKLLEENKAILNKKNEIGADTEAEEGEEDKEIQIPVSMAAEEEYLRSKVLSELLTDTLENDGEMYGNENEVLAALNGAYDKALLRLFASACSDQNVEKALSLAHELKQDRALTAAVKISERAELPSLVKKINNIREARYEQQLK", "length": 927 }, "evidence": [ { "id": "A0A1D5PDL4", "url": "https://omabrowser.org/oma/group/A0A1D5PDL4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDL4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1099, "end_pos": 1101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PDL4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PDL4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDL4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PDL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDL4" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 1010, "end_pos": 1064, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 421 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1099, "end_pos": 1101 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PDQ9-1", "uniprot_ac": "A0A1D5PDQ9", "uniprot_id": "A0A1D5PDQ9_CHICK", "mass": { "chemical_mass": 36261.0, "monoisotopic_mass": 36261.0 }, "refseq": { "ac": "XP_004943671", "name": "dual oxidase maturation factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" }, "gene_names": [ { "name": "DUOXA1L", "type": "recommended", "evidence": [ { "id": "A0A1D5PDQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ] }, { "name": "DUOXA1L", "type": "synonym", "evidence": [ { "id": "XP_004943671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" } ] } ], "protein_names": [ { "name": "Dual oxidase maturation factor 2", "type": "recommended", "evidence": [ { "id": "A0A1D5PDQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9/entry#names_and_taxonomy" } ] }, { "name": "dual oxidase maturation factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DUOXA1L", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9", "locus": {} } ], "crossref": [ { "id": "A0A1D5PDQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427483", "url": "https://www.ncbi.nlm.nih.gov/gene/427483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHINITY", "url": "https://omabrowser.org/oma/group/MHINITY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDQ9", "url": "https://www.orthodb.org/?gene=A0A1D5PDQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31158:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31158:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-209968", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLFDGIYPFYLQQRKSFVFDVSTIIVVIVFLMLASTFLLIIPGIRGRVRLYWMVRALFSLMVGVVIVVVQFTGDWESGWVTANTSYKSFSCAVVNVDIGLHVGLAGVNITLVGNPVNQVNETINYNEHFAWSFDADYDHSYGEGLEKGLPSPILYVAEKFTTQSPCNVHRQYRISSHYASASLWVAFCTWLISNMLFSTPVLVYGGYMILFTGAFMIFSLLSFSTVRNSLVCPIQFGTTSLWISYGGSFWLTLAVGLLCFVAGITVVALHYFNPELLKTFFDLHENKAEDYREMTEVYVNLQFMNSTLSPPQPSKLTPNDI", "length": 322, "header": "tr|A0A1D5PDQ9-1|A0A1D5PDQ9_CHICK Isoform 1 of Dual oxidase maturation factor 2 OS=Gallus gallus OX=9031 GN=DUOXA1L PE=3 SV=1 CANONICAL=A0A1D5PDQ9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9/entry", "sequence": { "sequence": "MTLFDGIYPFYLQQRKSFVFDVSTIIVVIVFLMLASTFLLIIPGIRGRVRLYWMVRALFSLMVGVVIVVVQFTGDWESGWVTANTSYKSFSCAVVNVDIGLHVGLAGVNITLVGNPVNQVNETINYNEHFAWSFDADYDHSYGEGLEKGLPSPILYVAEKFTTQSPCNVHRQYRISSHYASASLWVAFCTWLISNMLFSTPVLVYGGYMILFTGAFMIFSLLSFSTVRNSLVCPIQFGTTSLWISYGGSFWLTLAVGLLCFVAGITVVALHYFNPELLKTFFDLHENKAEDYREMTEVYVNLQFMNSTLSPPQPSKLTPNDI", "length": 322, "header": "tr|A0A1D5PDQ9-1|A0A1D5PDQ9_CHICK Isoform 1 of Dual oxidase maturation factor 2 OS=Gallus gallus OX=9031 GN=DUOXA1L PE=3 SV=1 CANONICAL=A0A1D5PDQ9-1" }, "locus": { "chromosome": "10", "start_pos": 1069284, "end_pos": 1064337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054426.1", "url": "https://www.ensembl.org/id/ENSGALT00010054426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032875.1", "url": "https://www.ensembl.org/id/ENSGALP00010032875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427483", "resource": "KEGG Pathway" }, { "id": "R-GGA-209968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "resource": "Reactome", "description": "Thyroxine biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RUR8-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "DUOXA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLWNGVLPFYPQPRHAAGLSVPLLIVILVFLVLAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAAHFSAEWSVGSVSTKTSYKAFSVERVRAHVGLHVGLEGVNITLTGNPVQQLNETIDYNEQFIWRFGQNYAGAYAEALERGLPNPVLYLAEKFTPSSPCGVYRQYRLAGHYASATLWVAFCFWLLSNMLLSMPVPHYGGLTLLITGAFALFSVFAFASISSVPLCQLRVGSSELTTHYGAAFWITLATGVLCLLLGAAVLSLHYARPSALRLFLEGSVNDLESPTKGSSPLILSNPLHKQFKTSDLTISTNL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEJ5-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLIPAAGGHTLPQLVLGEEHRDITQVPHLHDALSGTTWMTAWDGVLPFYPQPRHAAGFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSTSRVQVHVGLHVGLEGVNITLRGTPMQQLNETIDYNEQFTWRLNEDYTKEYVQALEKGLPDPVLYLAEKFTPNSPCGLYHQYHYAGHYAGATLWVAFCFWIIANALLSMPAPLYGGLALLITGAFTLFSVFAFASISSVPLCHFRLGSAALTPHYGASFWVTLATGILSLLLGGLVVILHYTRPSVLRALLDQNVKDCSNQADGNSHFILDNPQHRQSKTPDLNVTTLL", "length": 360 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H0S2-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAWDGVMPFYPQSRHAAGFSVPLLIVIVVFLCLAASFLFILPGIRGHSRWFWLVRVFLSLFIGAEIVAVHFSGDWFVGAVWTNTSYKAFSTARVQVHVGLHVGLVGVNITLKGTPVQQLNETIDYNERFTWRLDEDYTKEYVDALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTSAFTLFAVFAFASVSSVPLCPFRLGSATLTPHYGASFWVTLATGILSLLLGAVVVILHYTKPSALRTFLDQSDKDCRGQAKGNSPLIFDNPQRKQFATPDLNITTVL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1HG44-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "DUOXA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLWNGVLPFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLNETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPLCPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAKDCSQERGGSPLILGDPLHKQAALPDLKCITTNL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D311-1", "protein_name": "Dual oxidase maturation factor 2", "gene_name": "Duoxa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAWDGVLPFYPQPRHAASFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSPSRVQVHVGLHVGLAGVNITLRGTPRQQLNETIDYNERFTWRLNEDYTKEYVHALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTGAFTLFGVFAFASISSVPLCHFRLGSAVLTPYYGASFWLTLATGILSLLLGGAVVILHYTRPSALRSFLDLSVKDCSNQAKGNSPLTLNNPQHEQLKSPDLNITTLL", "length": 320 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJQ7-1", "protein_name": "Moladietz, isoform F", "gene_name": "mol", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKGWFDAFRDDGGPTLYSFSNRTPVTGDVSIVAVSVLFATFYVAFLVIFPGVRKQKFTTFSTVTLSLFVGLVILITRLGSAWHVAHATIIAPYKAFSREKLPARIGTHIGLMHVNVTLTAIPIGNWTPPDIDYNERFTWEGANDMSANYRHALQRGLPFPILTVAEYFSLGREGFSWGGQYRAAGYFASIMLWASLASWLLMNLLLIAVPRYGAYMKALTGALLVCTTVGYHCLLPKRPLSIHLEGGRLEFHFGWCYWLVLVAGILCFIAGVLISIIDLVWPHTFSTVLEVYYGTPYDRHVILEESSDVRYRKPRNSRSLEDPPGLGSRILRRLSSKARDLQPGTAPRRDSPAGVSSSGGVENKGFQSDAPKSPWRYPFRRSQQMAQQQHSHPLHQHPLQQHHQHHQHHHQQQLQFVGGPVVQHPMHHMQRTMSQDSGSSIASAAVQISPLHKHALARMLPNPPVERIRDMDHW", "length": 474 }, "evidence": [ { "id": "A0A1D5PDQ9", "url": "https://omabrowser.org/oma/group/A0A1D5PDQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PDQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PDQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDQ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A1D5PDS8-1", "uniprot_ac": "A0A1D5PDS8", "uniprot_id": "A0A1D5PDS8_CHICK", "mass": { "chemical_mass": 28463.0, "monoisotopic_mass": 28463.0 }, "refseq": { "ac": "XP_003643860", "name": "transmembrane protein 101", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643860" }, "gene_names": [ { "name": "TMEM101", "type": "recommended", "evidence": [ { "id": "A0A1D5PDS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8" } ] }, { "name": "TMEM101", "type": "synonym", "evidence": [ { "id": "XP_003643860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643860" } ] } ], "protein_names": [ { "name": "Transmembrane protein 101", "type": "synonym", "evidence": [ { "id": "A0A1D5PDS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 101", "type": "synonym", "evidence": [ { "id": "XP_003643860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643860" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643860" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM101", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8", "locus": { "chromosome": "27", "start_pos": 2699196, "end_pos": 2696846, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024968", "url": "https://www.ensembl.org/id/ENSGALG00010024968" } ] } } ], "crossref": [ { "id": "A0A1D5PDS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043148", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043148", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859387", "url": "https://www.ncbi.nlm.nih.gov/gene/100859387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859387", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859387", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVEFWNQ", "url": "https://omabrowser.org/oma/group/HVEFWNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDS8", "url": "https://www.orthodb.org/?gene=A0A1D5PDS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31034:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31034:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDS8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGRGWRRRALRLLTAGGGVLLTRFPFWHCFSGLLLCAERADGRRKPDIPVPYLYVDMGVAVLCASFMSFGVKRRWFALGAALQLAVATYASHIGGHVHYGDWLKVRMYSRTIAIIGGFLILASGAGELYRQKPRSRSLQSTGQVFLGIYLICQAYSLQHSKEDRLAYLNHILGGELTLQLLFVLYGLLALAFLSGYYVRVAAQVLAVLLPLAILLIDGNIGYWHEARRVEFWNQMKLIGQNVGIFGAVVILATDG", "length": 257, "header": "tr|A0A1D5PDS8-1|A0A1D5PDS8_CHICK Isoform 1 of Transmembrane protein 101 OS=Gallus gallus OX=9031 GN=TMEM101 PE=4 SV=2 CANONICAL=A0A1D5PDS8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDS8/entry", "sequence": { "sequence": "MAAGRGWRRRALRLLTAGGGVLLTRFPFWHCFSGLLLCAERADGRRKPDIPVPYLYVDMGVAVLCASFMSFGVKRRWFALGAALQLAVATYASHIGGHVHYGDWLKVRMYSRTIAIIGGFLILASGAGELYRQKPRSRSLQSTGQVFLGIYLICQAYSLQHSKEDRLAYLNHILGGELTLQLLFVLYGLLALAFLSGYYVRVAAQVLAVLLPLAILLIDGNIGYWHEARRVEFWNQMKLIGQNVGIFGAVVILATDG", "length": 257, "header": "tr|A0A1D5PDS8-1|A0A1D5PDS8_CHICK Isoform 1 of Transmembrane protein 101 OS=Gallus gallus OX=9031 GN=TMEM101 PE=4 SV=2 CANONICAL=A0A1D5PDS8-1" }, "locus": { "chromosome": "27", "start_pos": 2698966, "end_pos": 2696865, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060969.1", "url": "https://www.ensembl.org/id/ENSGALT00010060969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037717.1", "url": "https://www.ensembl.org/id/ENSGALP00010037717.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859387", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8PYE5-1", "protein_name": "Transmembrane protein 101", "gene_name": "tmem101", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAATRKKALRFFSQFGAFILTRFGFWNCFAMLMLFAERADVKRKPDIQVPYLYIDLGAAVLCASFMSFGVKRRWFALAAAIHLALSTYVSYVGGQVHYGDWLKVRMYSRAMAIIGGFLILSSGAGEVYRQKPRTRSLQSTGQVFLGIYLICMVYSLQHSKEDRLAYLDHIPGGELTVQLLVLVFGVLALAYLSGCYVRVASQILAVLLPLVILFIDGNFGYWHRSCRVEFWNQMKLIGQNVGIFGAVLILATDS", "length": 255 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8D0J2S3-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASKMGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAVSTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHSTRRVEFWNQMKLLGESVGIFGTAIILATDG", "length": 257 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HLI9-1", "protein_name": "Transmembrane protein 101 isoform X1", "gene_name": "Tmem101", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMAAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQMFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V8U1-1", "protein_name": "Transmembrane protein 101", "gene_name": "Tmem101", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGEVGGQKSEHLDREELVLRQIGRCSGSAVRPELMWRPQQKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 252 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIB3-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASKTGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYVGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGVYLVCVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q91VP7-1", "protein_name": "Transmembrane protein 101", "gene_name": "Tmem101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYTAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96IK0-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGILALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG", "length": 257 }, "evidence": [ { "id": "A0A1D5PDS8", "url": "https://omabrowser.org/oma/group/A0A1D5PDS8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PDS8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PDS8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDS8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PDZ1-1", "uniprot_ac": "A0A1D5PDZ1", "uniprot_id": "A0A1D5PDZ1_CHICK", "mass": { "chemical_mass": 12973.0, "monoisotopic_mass": 12973.0 }, "refseq": { "ac": "XP_418266", "name": "protein FAM32A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418266" }, "gene_names": [ { "name": "FAM32A", "type": "recommended", "evidence": [ { "id": "A0A1D5PDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1" } ] }, { "name": "FAM32A", "type": "synonym", "evidence": [ { "id": "XP_418266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418266" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 32 member A", "type": "synonym", "evidence": [ { "id": "A0A1D5PDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1/entry#names_and_taxonomy" } ] }, { "name": "protein FAM32A", "type": "synonym", "evidence": [ { "id": "XP_418266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418266" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418266.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418266" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM32A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1", "locus": { "chromosome": "28", "start_pos": 4864031, "end_pos": 4865720, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027951", "url": "https://www.ensembl.org/id/ENSGALG00010027951" } ] } } ], "crossref": [ { "id": "A0A1D5PDZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036474", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420150", "url": "https://www.ncbi.nlm.nih.gov/gene/420150", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420150", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420150", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLSEHHD", "url": "https://omabrowser.org/oma/group/QLSEHHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDZ1", "url": "https://www.orthodb.org/?gene=A0A1D5PDZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE24", "url": "https://www.orthodb.org/?gene=A0A8V1AE24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGK9", "url": "https://www.orthodb.org/?gene=A0A8V1AGK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13282:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13282:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADYEAVQRGPLRLKGGGAGLGAGKRKKKKAKEKAQILEQIVSSKKQEEEKKRGLDKRTPAQVAYEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112, "header": "tr|A0A1D5PDZ1-1|A0A1D5PDZ1_CHICK Isoform 1 of Family with sequence similarity 32 member A OS=Gallus gallus OX=9031 GN=FAM32A PE=3 SV=1 CANONICAL=A0A1D5PDZ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1/entry", "sequence": { "sequence": "MADYEAVQRGPLRLKGGGAGLGAGKRKKKKAKEKAQILEQIVSSKKQEEEKKRGLDKRTPAQVAYEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112, "header": "tr|A0A1D5PDZ1-1|A0A1D5PDZ1_CHICK Isoform 1 of Family with sequence similarity 32 member A OS=Gallus gallus OX=9031 GN=FAM32A PE=3 SV=1 CANONICAL=A0A1D5PDZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4865302, "end_pos": 4864668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067745.1", "url": "https://www.ensembl.org/id/ENSGALT00010067745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041488.1", "url": "https://www.ensembl.org/id/ENSGALP00010041488.1" } ] } }, { "isoform_ac": "A0A8V1AE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE24/entry", "sequence": { "sequence": "VPLQQQVGFTDSVHICRKKKKAKEKAQILEQIVSSKKQEEEKKRGLDKRTPAQVAYEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 103, "header": "tr|A0A8V1AE24-1|A0A1D5PDZ1_CHICK Computationally mapped isoform of Family with sequence similarity 32 member A OS=Gallus gallus OX=9031 GN=FAM32A PE=3 SV=1 CANONICAL=A0A1D5PDZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4865718, "end_pos": 4864668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067747.1", "url": "https://www.ensembl.org/id/ENSGALT00010067747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041490.1", "url": "https://www.ensembl.org/id/ENSGALP00010041490.1" } ] } }, { "isoform_ac": "A0A8V1AGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK9/entry", "sequence": { "sequence": "MQQPPTFTHPGALKQAAVIQTRKKKKAKEKAQILEQIVSSKKQEEEKKRGLDKRTPAQVAYEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 108, "header": "tr|A0A8V1AGK9-1|A0A1D5PDZ1_CHICK Computationally mapped isoform of Family with sequence similarity 32 member A OS=Gallus gallus OX=9031 GN=FAM32A PE=3 SV=1 CANONICAL=A0A1D5PDZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4865555, "end_pos": 4864668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067746.1", "url": "https://www.ensembl.org/id/ENSGALT00010067746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041489.1", "url": "https://www.ensembl.org/id/ENSGALP00010041489.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420150", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420150", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UYF2-1", "protein_name": "Protein FAM32A", "gene_name": "FAM32A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDYEQVQRGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6QR31-1", "protein_name": "Protein FAM32A", "gene_name": "FAM32A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZUE5-1", "protein_name": "Protein FAM32A", "gene_name": "Fam32al1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASTMEAYEQVQKGPLKLKGVAELGVTKRRKKKDKDKAKMLETMGMRKKSEEEKQHCLDKRTPAQAAFEKMQEKRQTERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 116 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54QB3-1", "protein_name": "DUF1754 family protein", "gene_name": "fam32", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYSNVVTGKLKLKGDVPEIPSHTNKKKKKSKKVKNELIKEEQQQHEEEEISNIKVSKTLTDAEKKHKEKLSRKEQKRIDKLVNKSHKEKIEEYNKYLSSLSEHHDVPKVGPG", "length": 112 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6GQN4-1", "protein_name": "Protein FAM32A-like", "gene_name": "fam32al", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEYKSVQKGSLKLKGVSLPSKKKKKKNKEMKRLEEQVLTSENEEGTKKAYVDKRTPAQMAFDKIQEKRQMERILKKASKTHKRRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 109 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CR80-1", "protein_name": "Protein FAM32A", "gene_name": "Fam32a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKMLEAMGTSKKSEEEKRRCLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y421-1", "protein_name": "Protein FAM32A", "gene_name": "FAM32A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK", "length": 112 }, "evidence": [ { "id": "A0A1D5PDZ1", "url": "https://omabrowser.org/oma/group/A0A1D5PDZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PDZ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 112, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PDZ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PDZ1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PE57-1", "uniprot_ac": "A0A1D5PE57", "uniprot_id": "A0A1D5PE57_CHICK", "mass": { "chemical_mass": 139298.0, "monoisotopic_mass": 139298.0 }, "refseq": { "ac": "NP_990711", "name": "collagen alpha-1(III) chain precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" }, "gene_names": [ { "name": "COL3A1", "type": "recommended", "evidence": [ { "id": "A0A1D5PE57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57" } ] }, { "name": "COL3A1", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] }, { "name": "collagen", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] } ], "protein_names": [ { "name": "Collagen type III alpha 1 chain", "type": "synonym", "evidence": [ { "id": "A0A1D5PE57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57/entry#names_and_taxonomy" } ] }, { "name": "alpha-1 type III collagen", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] }, { "name": "collagen alpha-1(III) chain precursor", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] }, { "name": "collagen alpha-1(III) chain", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] }, { "name": "collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)", "type": "synonym", "evidence": [ { "id": "NP_990711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000235.1. On or before Sep 26, 2008 this sequence version replaced XP_421847.2, NP_990711.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_990711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PE57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL3A1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57", "locus": { "chromosome": "7", "start_pos": 670613, "end_pos": 721510, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013170", "url": "https://www.ensembl.org/id/ENSGALG00010013170" } ] } } ], "crossref": [ { "id": "ENSGALG00000035584", "url": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-186797", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186797", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000171", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PE57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PE57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1460, "header": "tr|A0A1D5PE57-1|A0A1D5PE57_CHICK Isoform 1 of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PE57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE57/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1460, "header": "tr|A0A1D5PE57-1|A0A1D5PE57_CHICK Isoform 1 of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031600.1", "url": "https://www.ensembl.org/id/ENSGALT00010031600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018468.1", "url": "https://www.ensembl.org/id/ENSGALP00010018468.1" } ] } }, { "isoform_ac": "A0A8V0YCJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ3/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1406, "header": "tr|A0A8V0YCJ3-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031659.1", "url": "https://www.ensembl.org/id/ENSGALT00010031659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018521.1", "url": "https://www.ensembl.org/id/ENSGALP00010018521.1" } ] } }, { "isoform_ac": "A0A8V0YIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ7/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1340, "header": "tr|A0A8V0YIZ7-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031676.1", "url": "https://www.ensembl.org/id/ENSGALT00010031676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018533.1", "url": "https://www.ensembl.org/id/ENSGALP00010018533.1" } ] } }, { "isoform_ac": "A0A8V0YKV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV0/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1442, "header": "tr|A0A8V0YKV0-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031633.1", "url": "https://www.ensembl.org/id/ENSGALT00010031633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018498.1", "url": "https://www.ensembl.org/id/ENSGALP00010018498.1" } ] } }, { "isoform_ac": "A0A8V0YKX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX4/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1370, "header": "tr|A0A8V0YKX4-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031664.1", "url": "https://www.ensembl.org/id/ENSGALT00010031664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018524.1", "url": "https://www.ensembl.org/id/ENSGALP00010018524.1" } ] } }, { "isoform_ac": "A0A8V0YKX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX9/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1343, "header": "tr|A0A8V0YKX9-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031670.1", "url": "https://www.ensembl.org/id/ENSGALT00010031670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018529.1", "url": "https://www.ensembl.org/id/ENSGALP00010018529.1" } ] } }, { "isoform_ac": "A0A8V0YKY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY2/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTQLMFPSMVSFFDHQPGFSSVSKIQNSIHAQRHISLEKI", "length": 1450, "header": "tr|A0A8V0YKY2-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 670916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031680.1", "url": "https://www.ensembl.org/id/ENSGALT00010031680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018534.1", "url": "https://www.ensembl.org/id/ENSGALP00010018534.1" } ] } }, { "isoform_ac": "A0A8V0YQN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN3/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1444, "header": "tr|A0A8V0YQN3-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031614.1", "url": "https://www.ensembl.org/id/ENSGALT00010031614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018481.1", "url": "https://www.ensembl.org/id/ENSGALP00010018481.1" } ] } }, { "isoform_ac": "A0A8V0YQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR3/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGLPGPPGPLGPQGAIGSPGASGARGPPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1435, "header": "tr|A0A8V0YQR3-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031648.1", "url": "https://www.ensembl.org/id/ENSGALT00010031648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018512.1", "url": "https://www.ensembl.org/id/ENSGALP00010018512.1" } ] } }, { "isoform_ac": "A0A8V0YQR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR8/entry", "sequence": { "sequence": "MMSFVQKVSLFILAVFQPSVILAQQDALGGCTHLGQEYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCPVCPQTTPQPTKLPYTQGPKGDPGSPGSPGRTGAPGPPGQPGSPGAPGPPGICQSCPSISGGSFSPQYDSYDVKAGSVGMGYPPQPISGFPGPPGPSGPPGPPGHAGPPGSNGYQGPPGEPGQPGPSGPPGPAGMIGPAGPPGKDGEPGRPGRNGDRGIPGLPGHKGHPGMPGMPGMKGARGFDGKDGAKGDSGAPGPKGEAGQPGANGSPGQPGPRGPTGERGRPGNPGGPGAHGKDGAPGAAGPPGPPGPPGTAGFPGSPGFKGEAGPPGPAGASGSPGERGEPGPQGQAGPPGPQGPPGRAGSPGNKGEMGPSGIPGAPGLPGGRGLPGPPGTSGNPGAKGTPGEPGKNGAKGDPGPKGERGENGTPGAPGPPGEEGKRGANGEPGQNGVPGTPGERGSPGFRGLPGSNGLPGEKGPAGERGSPGPPGPSGPAGDRGQDGGPGLPGMRGLPGIPGSPGSDGKPGPPGNQGEPGRSGPPGPAGPRGQPGVMGFPGPKGNEGAPGKNGERGPGGPPGTPGPAGKNGDVGLPGPPGPAGPAGDRGEPGPSGSPGLQGLPGGPGPAGENGKPGEPGPKGDIGGPGFPGPKGENGIPGERGAQGPPGPTGARGGPGPAGSEGAKGPPGPPGAPGGTGLPGLQGMPGERGASGSPGPKGDKGEPGGKGADGLPGARGERGNVGPIGPPGPAGPPGDKGETGPAGAPGPAGSRGGPGERGEQGLPGPAGFPGAPGQNGEPGGKGERGPPGLRGEAGPPGAAGPQGGPGAPGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGNNGSPGPPGNAGPPGKDGPPGPPGNTGPPGGSGPPGLRGEPGAPGEKGPPGARGERGTPGDPGPQGIIGSRGSTGLPGPRGLPGPAGMAGGKGEDGKPGVNGVPGERGAPGPQGPMGQRGLPGEPGRDGNPGSDGSPGRDGSPGGKGDRGESGPPGVPGPPGHPGPAGNNGAPGKAGERGFQGPPGPPGSAGPAGARGPAGPQGPRGDKGETGERGSAGIKGHRGFPGTPGPAGPPGKDGRGGYPGPIGPPGPRGNRGESGPAGPPGQPGLPGPSGPPGPCCGGGVASLGAGEKGPVGYGYEYRDEPKENEINLGEIMSSMKSINNQIENILSPDGSRKNPARNCRDLKFCHPELKSGEYWIDPNQGCKMDAIKVYCNMETGETCLSANPATVPRKNWWTTESSGKKHVWFGESMKGGFQFSYGDPDLPEDVSEVQLAFLRILSSRASQNITYHCKNSIAYMDQASGNVKKALKLMSSVETEIKAEGNSKYMYAVLEDGCTKHTGEWGKTVFEYRTRKTMRLPVVDIAPIDIGGPDQEFGVDVGPVCFL", "length": 1433, "header": "tr|A0A8V0YQR8-1|A0A1D5PE57_CHICK Computationally mapped isoform of Collagen type III alpha 1 chain OS=Gallus gallus OX=9031 GN=COL3A1 PE=1 SV=1 CANONICAL=A0A1D5PE57-1" }, "locus": { "chromosome": "7", "start_pos": 721383, "end_pos": 672211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031654.1", "url": "https://www.ensembl.org/id/ENSGALT00010031654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018517.1", "url": "https://www.ensembl.org/id/ENSGALP00010018517.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1113, "start_aa": "Thr", "end_pos": 1113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1113", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 480, "start_aa": "Thr", "end_pos": 480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 603, "start_aa": "Thr", "end_pos": 603, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr603", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 691, "start_aa": "Thr", "end_pos": 691, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr691", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396340", "resource": "KEGG Pathway" }, { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1566977", "name": "", 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"id": "XP_040557934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557934" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PE94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 178B-like", "type": "synonym", "evidence": [ { "id": "XP_040557934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557934" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PE94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121113288", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94", "locus": {} } ], "crossref": [ { "id": "A0A1D5PE94", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PE94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028327", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "121113288", "url": "https://www.ncbi.nlm.nih.gov/gene/121113288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HKRNANS", "url": "https://omabrowser.org/oma/group/HKRNANS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PE94", "url": "https://www.orthodb.org/?gene=A0A1D5PE94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32005:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32005:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PE94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PE94-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAQALSGAGLLLAAAALALLAVAIGTDSWYETDARRHRERCRGFGHKRSDPPGSMSAPSSHLPLRARPPRALLPGRPPAPAPAAAAAALDSHCGRRFNSTVSGLWRRCHRAGYEPDSEELIRKGVIQRCTAVKYHYTSSSLPRNLPINITNTIRQDEWHALHLRRMTAGFIGMAVSIILFGWIIGVLGCCKQQELMQYVAGLLFLMGGTCCIISLCTCVAGINFELSRYPRYVYGLPEDISHGYGWSMFCAWGGLGLTLLAGFLCTLAPSLNTSRASVQKPRQENGAV", "length": 291, "header": "tr|A0A1D5PE94-1|A0A1D5PE94_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121113288 PE=3 SV=1 CANONICAL=A0A1D5PE94-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PE94-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94/entry", "sequence": { "sequence": "MAAAAQALSGAGLLLAAAALALLAVAIGTDSWYETDARRHRERCRGFGHKRSDPPGSMSAPSSHLPLRARPPRALLPGRPPAPAPAAAAAALDSHCGRRFNSTVSGLWRRCHRAGYEPDSEELIRKGVIQRCTAVKYHYTSSSLPRNLPINITNTIRQDEWHALHLRRMTAGFIGMAVSIILFGWIIGVLGCCKQQELMQYVAGLLFLMGGTCCIISLCTCVAGINFELSRYPRYVYGLPEDISHGYGWSMFCAWGGLGLTLLAGFLCTLAPSLNTSRASVQKPRQENGAV", "length": 291, "header": "tr|A0A1D5PE94-1|A0A1D5PE94_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121113288 PE=3 SV=1 CANONICAL=A0A1D5PE94-1" }, "locus": { "chromosome": "5", "start_pos": 22426636, "end_pos": 22416173, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054315.1", "url": "https://www.ensembl.org/id/ENSGALT00010054315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032805.1", "url": "https://www.ensembl.org/id/ENSGALP00010032805.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E7F7K7-1", "protein_name": "Transmembrane protein 178B", "gene_name": "tmem276b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAIKILTSAGLFLAFCALVLLAMAICTDYWYETDARRHRERCKNYANKRNDPGYIYISNHNLPLQMPPKGYERKATEPRVKRHIPASATAMESHCSRQFNSTISGLWRKCHREGFDLQTEDLILNGLIQRCTPVKYHYTSSILPRNLPANITKTIRQDEWHALHLRRMTAGFVGMAVSIILFGWIIGVLGCCQQHDLMQYVAGLLFLMGGTCCIISLCTCVAGINFELSRYPRYLYGLPEDISHGYGWSMFCAWGGLGLTLLAGFLCTLAPSLSSPLARTTVHKSRHENGTV", "length": 293 }, "evidence": [ { "id": "A0A1D5PE94", "url": "https://omabrowser.org/oma/group/A0A1D5PE94/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PE94", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PE94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PE94-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 291, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PE94-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PE94" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 275, "end_pos": 277 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PEC4-1", "uniprot_ac": "A0A1D5PEC4", "uniprot_id": "A0A1D5PEC4_CHICK", "mass": { "chemical_mass": 59456.0, "monoisotopic_mass": 59456.0 }, "refseq": { "ac": "XP_015141132", "name": "calcium uptake protein 3, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141132" }, "gene_names": [ { "name": "MICU3", "type": "recommended", "evidence": [ { "id": "A0A1D5PEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ] }, { "name": "MICU3", "type": "synonym", "evidence": [ { "id": "XP_015141132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141132" } ] } ], "protein_names": [ { "name": "Mitochondrial calcium uptake family member 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4/entry#names_and_taxonomy" } ] }, { "name": "calcium uptake protein 3, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141132.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MICU3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4", "locus": { "chromosome": "4", "start_pos": 62729345, "end_pos": 62777589, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016200", "url": "https://www.ensembl.org/id/ENSGALG00010016200" } ] } } ], "crossref": [ { "id": "A0A1D5PEC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013661", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013661", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422736", "url": "https://www.ncbi.nlm.nih.gov/gene/422736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422736", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEPAYPM", "url": "https://omabrowser.org/oma/group/DEPAYPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PEC4", "url": "https://www.orthodb.org/?gene=A0A1D5PEC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV49", "url": "https://www.orthodb.org/?gene=A0A8V0YV49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVF7", "url": "https://www.orthodb.org/?gene=F1NVF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12294:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12294:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8949215", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949215", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8949664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVF7", "url": "https://www.uniprot.org/uniprotkb/F1NVF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVF7-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRTLLRWRRRLGSAPSAPSARRLWAGGGAGPAGPRRWRRELGWAAGAALAGYAGYQLSERRREPSRQPAAAEAGGARALLPIPVAAAAKETVTENRSDLEDLHLYATPREQRFRRFASLEFEGQLYMTPYDFIQAVTNDEPKRAKKWRSLSKQELNQILMETPPVWKGSSKLFRNLNEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRERKGDEEKRAMLRLQLYGYHTPTNSVLKTEGEDLVPRSYWDTLRRSTSQALFSDLAERSDDLASSLSDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSSYLENMRCRIPEEKGITFDEFRSFFQFLNNLEDFTIAMQMYNFASRSIGQDEFKRAVYVATGVKLSPHLVNTVFKIFDVDRDDQLSYKEFIGIMKDRLNRGFRESPKYGWKEYYSCVMTVTSEHLRDLWKQFRRRDMLR", "length": 511, "header": "tr|A0A1D5PEC4-1|A0A1D5PEC4_CHICK Isoform 1 of Mitochondrial calcium uptake family member 3 OS=Gallus gallus OX=9031 GN=MICU3 PE=4 SV=2 CANONICAL=A0A1D5PEC4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4/entry", "sequence": { "sequence": "MAALRTLLRWRRRLGSAPSAPSARRLWAGGGAGPAGPRRWRRELGWAAGAALAGYAGYQLSERRREPSRQPAAAEAGGARALLPIPVAAAAKETVTENRSDLEDLHLYATPREQRFRRFASLEFEGQLYMTPYDFIQAVTNDEPKRAKKWRSLSKQELNQILMETPPVWKGSSKLFRNLNEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRERKGDEEKRAMLRLQLYGYHTPTNSVLKTEGEDLVPRSYWDTLRRSTSQALFSDLAERSDDLASSLSDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSSYLENMRCRIPEEKGITFDEFRSFFQFLNNLEDFTIAMQMYNFASRSIGQDEFKRAVYVATGVKLSPHLVNTVFKIFDVDRDDQLSYKEFIGIMKDRLNRGFRESPKYGWKEYYSCVMTVTSEHLRDLWKQFRRRDMLR", "length": 511, "header": "tr|A0A1D5PEC4-1|A0A1D5PEC4_CHICK Isoform 1 of Mitochondrial calcium uptake family member 3 OS=Gallus gallus OX=9031 GN=MICU3 PE=4 SV=2 CANONICAL=A0A1D5PEC4-1" }, "locus": { "chromosome": "4", "start_pos": 62777545, "end_pos": 62731654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038919.1", "url": "https://www.ensembl.org/id/ENSGALT00010038919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022489.1", "url": "https://www.ensembl.org/id/ENSGALP00010022489.1" } ] } }, { "isoform_ac": "A0A8V0YV49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV49/entry", "sequence": { "sequence": "MAALRTLLRWRRRLGSAPSAPSARRLWAGGGAGPAGPRRWRRELGWAAGAALAGYAGYQLSERRREPSRQPAAAEAGGARALLPIPVAAAAKETVTENRSDLEDLHLYATPREQRFRRFASLEFEGQLYMTPYDFIQAVTNDEPKRAKKWRSLSKQELNQILMETPPVWKGSSKLFRNLNEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRERKGDEEKRAMLVLKTEGEDLVPRSYWDTLRRSTSQALFSDLAERSDDLASSLSDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSSYLENMRCRIPEEKGITFDEFRSFFQFLNNLEDFTIAMQMYNFASRSIGQDEFKRAVYVATGVKLSPHLVNTVFKIFDVDRDDQLSYKEFIGIMKDRLNRGFRGYKPIQRYTTFKSCVRKELYSR", "length": 484, "header": "tr|A0A8V0YV49-1|A0A1D5PEC4_CHICK Computationally mapped isoform of Mitochondrial calcium uptake family member 3 OS=Gallus gallus OX=9031 GN=MICU3 PE=4 SV=1 CANONICAL=A0A1D5PEC4-1" }, "locus": { "chromosome": "4", "start_pos": 62777545, "end_pos": 62736911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038928.1", "url": "https://www.ensembl.org/id/ENSGALT00010038928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022494.1", "url": "https://www.ensembl.org/id/ENSGALP00010022494.1" } ] } }, { "isoform_ac": "F1NVF7-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF7/entry", "sequence": { "sequence": "MAALRTLLRWRRRLGSAPSAPSARRLWAGGGAGPAGPRRWRRELGWAAGAALAGYAGYQLSERRREPSRQPAAAEAGGARALLPIPVAAAAKETVTENRSDLEDLHLYATPREQRFRRFASLEFEGQLYMTPYDFIQAVTNDEPKRAKKWRSLSKQELNQILMETPPVWKGSSKLFRNLNEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRERKGDEEKRAMLRLQLYGYHTPTNSVLKTEGEDLVPRSYWDTLRRSTSQALFSDLAERSDDLASSLSDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSSYLENMRCRIPEEKGITFDEFRSFFQFLNNLEDFTIAMQMYNFASRSIGQDEFKRAVYVATGVKLSPHLVNTVFKIFDVDRDDQLSYKEFIGIMKDRLNRGFRGYKPIQRYTTFKSCVRKELYSR", "length": 497, "header": "tr|F1NVF7-1|A0A1D5PEC4_CHICK Computationally mapped isoform of Mitochondrial calcium uptake family member 3 OS=Gallus gallus OX=9031 GN=MICU3 PE=4 SV=2 CANONICAL=A0A1D5PEC4-1" }, "locus": { "chromosome": "4", "start_pos": 62777545, "end_pos": 62736911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038924.1", "url": "https://www.ensembl.org/id/ENSGALT00010038924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022492.1", "url": "https://www.ensembl.org/id/ENSGALP00010022492.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422736", "resource": "KEGG Pathway" }, { "id": "R-GGA-8949215", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949215", "resource": "Reactome", "description": "Mitochondrial calcium ion transport" }, { "id": "R-GGA-8949664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "resource": "Reactome", "description": "Processing of SMDT1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHF1-1", "protein_name": "Mitochondrial calcium uptake 3, isoform D", "gene_name": "MICU3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGLAARLTVKNCTIIAQRSSVIVGVGRSARFSSSSSQMGRIPGHKTRRLLTIVGGSAVSLAALAAFIKLRSAENPVNAVSLKRRMRDDSELENVKLTARERRFIKFASVEYDDQLYMTPQDFLDSVVEQEPRPRLKRRQLSSDEVDKYKENTPALKKGSTRLFRNLRDKGIVSYTEYLFLLSILTKPKSGFRIAFNMFDTDGNQRVDKDEFLVIISILAGALKDTQNVDPQTKRILSRLVSYDEQSQMTKPMAVPQAKRGIMERIFSGAWKEKHGEQEPEEELATPTPLEQNYVNDGEGLQRRHMVATTLQLHFFGKRGTGVINYDNFYRFMDNLQTEVLELEFHEFSKGNSVISELDFAKILLRYTYLATDEYDVFLERLLERVKDEKGISFHDFRDFCHFLNNLDDFTIAMRMYTLADRAISKDEFSRAVKICTGYKLSPHLIDTVFAIFDADGDGLLSYKEFIAIMKDRLHRGFKVSGRFFDYNEALDAYDEPDYPLFVAWRHRVCRHLDYFIDSDALWH", "length": 524 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6A2H6-1", "protein_name": "Calcium uptake protein 3, mitochondrial", "gene_name": "Micu3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRRLLWPPPRLSPTLAPQQPFLSPWGRPAGTAPGMSGRPFSGREEDEGAVAEAAWRRRRWGELSIAAAAGGGLVGLVCYQLYGDPRADPSELVAPELDESPRGRGLLPIPVAAAKETVATGRAVTEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKFAKTWKSLSKQELSQMLSETPPVWKGSSKLFRNLKERGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVLKPDAEELVSRSYWDTLRRSTSQALFSDLAERADDITSLVADTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "length": 523 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MHU1-1", "protein_name": "Mitochondrial calcium uptake family member 3", "gene_name": "MICU3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALRRLLWPPPRLPPPCSPHHPAHGPWGRPAGTAPGPPGRPFSCREEDEGAVAEAAWRRRRRWRELSFAAAAGGGLVGLVCYQLYGDPRADSARAAGPWLPSDSAAAEPEDPPGGGGLFPIPVAAAKETVAVGRTEVEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKIAKTWKSLSKQELNQMLSETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDFAERADDITNLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "length": 533 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SET8-1", "protein_name": "Mitochondrial calcium uptake family member 3", "gene_name": "MICU3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGAACGGSPRPPGRPFSCREEEEGAVSEAAWRRRRRWGELSIAAAAGGGLVGLVCYQLYGDPRAESARAPGPWLPSESAAAEPQDLSRGRGLLPIPVAAAKETVAVGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKFAKTWKSLSKQELNQMLSETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVYSFYKTYRLYFNKAGKKCCYQLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "length": 527 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86XE3-1", "protein_name": "Calcium uptake protein 3, mitochondrial", "gene_name": "MICU3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIPVAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "length": 530 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CTY5-1", "protein_name": "Calcium uptake protein 3, mitochondrial", "gene_name": "Micu3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALRRFLWPPPRLSPALAPQQPFLSPWGRPAGTAPGMSGRPFSCREEDEGAVAEAAWRRRRWGELSIAAAAGGGLVGLVCYQLYGDPRADPSELAAPELEDPPRGRGLLPIPVAAAKETVATGRAITEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKFAKTWKSLSKQELSQMLSETPPVWKGSSKLFRNLKERGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVLKTDAGELVSRSYWDTLRRSTSQALFSDLAERADDITSLVADTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSISEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "length": 523 }, "evidence": [ { "id": "A0A1D5PEC4", "url": "https://omabrowser.org/oma/group/A0A1D5PEC4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "uniplex complex", "id": "GO:1990246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990246", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "calcium import into the mitochondrion", "id": "GO:0036444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036444", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PEC4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 511, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PEC4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEC4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEC4" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 234, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 370, "end_pos": 372 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PLW4-1", "uniprot_ac": "A0A1D5PLW4", "uniprot_id": "A0A1D5PLW4_CHICK", "mass": { "chemical_mass": 81369.0, "monoisotopic_mass": 81369.0 }, "refseq": { "ac": "XP_418708", "name": "transcription factor Sp4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418708" }, "gene_names": [ { "name": "SP4", "type": "recommended", "evidence": [ { "id": "A0A1D5PLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ] }, { "name": "SP4", "type": "synonym", "evidence": [ { "id": "XP_418708", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418708" } ] } ], "protein_names": [ { "name": "Sp4 transcription factor", "type": "synonym", "evidence": [ { "id": "A0A1D5PLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4/entry#names_and_taxonomy" } ] }, { "name": "transcription factor Sp4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418708", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418708" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418708.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418708" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4", "locus": { "chromosome": "2", "start_pos": 30337922, "end_pos": 30313353, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003824", "url": "https://www.ensembl.org/id/ENSGALG00010003824" } ] } } ], "crossref": [ { "id": "A0A1D5PLW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039454", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039454", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420607", "url": "https://www.ncbi.nlm.nih.gov/gene/420607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420607", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQQAILP", "url": "https://omabrowser.org/oma/group/NQQAILP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PEG4", "url": "https://www.orthodb.org/?gene=A0A1D5PEG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLW4", "url": "https://www.orthodb.org/?gene=A0A1D5PLW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLS5", "url": "https://www.orthodb.org/?gene=A0A8V0XLS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14947:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14947:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418708", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PEG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDQKKEETMPTEGEKSPEAENNNNNNKKGKTGGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPNQGLVQLQNQPQQLELVTTQLAGNSWQLVAASPSASKDNNVAQQGSSVASSAPSPSSSNNGSASPTKTKSGNSSATTPGQFQVIQVQNPSGSVQYQVIPQIQTTEGQQIQINPANATGLQDIQGQIQLIPAGNNQAILTASNRTASGNIIAQNLANQTVPVQIRPGVSIPLQLQTIPGTQAQVVTTLPINIGGVTLALPVINNMAAGGGSGQVGQSTEGGVSNGSQLASTPVTSASVSSMPDSPSSSSTSTTTASTSLTSSDTLVSSAETGQYTSTAGSSSEQPTEESQTTATDSEAQSSSQLQSNGLQNVQDQSGSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQSLQNVQLQAVSPTQVLIRAPTLTPSGQISWQTVQVQNLQSLSNLQVQNAGLPQQLTITPVSSSGGTTIAQIAPVAVAGTPITLNAAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANAGIGAVSPDQITQVQLQQAQQASDQEVQPGKRTRRVACSCPNCREGEGRSSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWVFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 780, "header": "tr|A0A1D5PLW4-1|A0A1D5PLW4_CHICK Isoform 1 of Sp4 transcription factor OS=Gallus gallus OX=9031 GN=SP4 PE=3 SV=1 CANONICAL=A0A1D5PLW4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEG4/entry", "sequence": { "sequence": "MPTEGEKSPEAENNNNNNKKGKTGGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPNQGLVQLQNQPQQLELVTTQLAGNSWQLVAASPSASKDNNVAQQGSSVASSAPSPSSSNNGSASPTKTKSGNSSATTPGQFQVIQVQNPSGSVQYQVIPQIQTTEGQQIQINPANATGLQDIQGQIQLIPAGNNQAILTASNRTASGNIIAQNLANQTVPVQIRPGVSIPLQLQTIPGTQAQVVTTLPINIGGVTLALPVINNMAAGGGSGQVGQSTEGGVSNGSQLASTPVTSASVSSMPDSPSSSSTSTTTASTSLTSSDTLVSSAETGQYTSTAGSSSEQPTEESQTTATDSEAQSSSQLQSNGLQNVQDQSGSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQSLQNVQLQAVSPTQVLIRAPTLTPSGQISWQTVQVQNLQSLSNLQVQNAGLPQQLTITPVSSSGGTTIAQIAPVAVAGTPITLNAAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANAGIGAVSPDQITQVQLQQAQQASDQEVQPGKRTRRVACSCPNCREGEGRSSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWVFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 771, "header": "tr|A0A1D5PEG4-1|A0A1D5PLW4_CHICK Computationally mapped isoform of Sp4 transcription factor OS=Gallus gallus OX=9031 GN=SP4 PE=3 SV=1 CANONICAL=A0A1D5PLW4-1" }, "locus": { "chromosome": "2", "start_pos": 30336069, "end_pos": 30314211, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008849.1", "url": "https://www.ensembl.org/id/ENSGALT00010008849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005193.1", "url": "https://www.ensembl.org/id/ENSGALP00010005193.1" } ] } }, { "isoform_ac": "A0A1D5PLW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4/entry", "sequence": { "sequence": "MSDQKKEETMPTEGEKSPEAENNNNNNKKGKTGGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPNQGLVQLQNQPQQLELVTTQLAGNSWQLVAASPSASKDNNVAQQGSSVASSAPSPSSSNNGSASPTKTKSGNSSATTPGQFQVIQVQNPSGSVQYQVIPQIQTTEGQQIQINPANATGLQDIQGQIQLIPAGNNQAILTASNRTASGNIIAQNLANQTVPVQIRPGVSIPLQLQTIPGTQAQVVTTLPINIGGVTLALPVINNMAAGGGSGQVGQSTEGGVSNGSQLASTPVTSASVSSMPDSPSSSSTSTTTASTSLTSSDTLVSSAETGQYTSTAGSSSEQPTEESQTTATDSEAQSSSQLQSNGLQNVQDQSGSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQSLQNVQLQAVSPTQVLIRAPTLTPSGQISWQTVQVQNLQSLSNLQVQNAGLPQQLTITPVSSSGGTTIAQIAPVAVAGTPITLNAAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANAGIGAVSPDQITQVQLQQAQQASDQEVQPGKRTRRVACSCPNCREGEGRSSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWVFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 780, "header": "tr|A0A1D5PLW4-1|A0A1D5PLW4_CHICK Isoform 1 of Sp4 transcription factor OS=Gallus gallus OX=9031 GN=SP4 PE=3 SV=1 CANONICAL=A0A1D5PLW4-1" }, "locus": { "chromosome": "2", "start_pos": 30336069, "end_pos": 30313573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008852.1", "url": "https://www.ensembl.org/id/ENSGALT00010008852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005196.1", "url": "https://www.ensembl.org/id/ENSGALP00010005196.1" } ] } }, { "isoform_ac": "A0A8V0XLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLS5/entry", "sequence": { "sequence": "MEDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPNQGLVQLQNQPQQLELVTTQLAGNSWQLVAASPSASKDNNVAQQGSSVASSAPSPSSSNNGSASPTKTKSGNSSATTPGQFQVIQVQNPSGSVQYQVIPQIQTTEGQQIQINPANATGLQDIQGQIQLIPAGNNQAILTASNRTASGNIIAQNLANQTVPVQIRPGVSIPLQLQTIPGTQAQVVTTLPINIGGVTLALPVINNMAAGGGSGQVGQSTEGGVSNGSQLASTPVTSASVSSMPDSPSSSSTSTTTASTSLTSSDTLVSSAETGQYTSTAGSSSEQPTEESQTTATDSEAQSSSQLQSNGLQNVQDQSGSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQSLQNVQLQAVSPTQVLIRAPTLTPSGQISWQTVQVQNLQSLSNLQVQNAGLPQQLTITPVSSSGGTTIAQIAPVAVAGTPITLNAAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANAGIGAVSPDQITQVQLQQAQQASDQEVQPGKRTRRVACSCPNCREGEGRSSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWVFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 746, "header": "tr|A0A8V0XLS5-1|A0A1D5PLW4_CHICK Computationally mapped isoform of Sp4 transcription factor OS=Gallus gallus OX=9031 GN=SP4 PE=3 SV=1 CANONICAL=A0A1D5PLW4-1" }, "locus": { "chromosome": "2", "start_pos": 30336069, "end_pos": 30314148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008846.1", "url": "https://www.ensembl.org/id/ENSGALT00010008846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005190.1", "url": "https://www.ensembl.org/id/ENSGALP00010005190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MGT2-1", "protein_name": "Sp4 transcription factor", "gene_name": "SP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSDQKKEEEEEAAQAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNISQPASSSSSSSTSNNGSASPTKTKSGNSSSPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINSVAAGGGTAQVGQPATTTESGTSNGSQLASTPTTTTASASMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTVEDSQTPAATESEAQSSSQLQSNGIQNTQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQASDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 783 }, "evidence": [ { "id": "A0A1D5PLW4", "url": "https://omabrowser.org/oma/group/A0A1D5PLW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABZ3NN46-1", "protein_name": "Sp4 transcription factor", "gene_name": "Sp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 780 }, "evidence": [ { "id": "A0A1D5PLW4", "url": "https://omabrowser.org/oma/group/A0A1D5PLW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02446-1", "protein_name": "Transcription factor Sp4", "gene_name": "SP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQLVSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIEESQTPAATESEAQSSSQLQPNGMQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 784 }, "evidence": [ { "id": "A0A1D5PLW4", "url": "https://omabrowser.org/oma/group/A0A1D5PLW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62445-1", "protein_name": "Transcription factor Sp4", "gene_name": "Sp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQDSHPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTTLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF", "length": 782 }, "evidence": [ { "id": "A0A1D5PLW4", "url": "https://omabrowser.org/oma/group/A0A1D5PLW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PLW4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 780, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PLW4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLW4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 643, "end_pos": 672, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 772, "end_pos": 774 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PEJ1-1", "uniprot_ac": "A0A1D5PEJ1", "uniprot_id": "A0A1D5PEJ1_CHICK", "mass": { "chemical_mass": 122483.0, "monoisotopic_mass": 122483.0 }, "refseq": {}, "gene_names": [ { "name": "CEBPZ", "type": "recommended", "evidence": [ { "id": "A0A1D5PEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ] } ], "protein_names": [ { "name": "CCAAT/enhancer-binding protein zeta", "type": "recommended", "evidence": [ { "id": "A0A1D5PEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1/entry#names_and_taxonomy" } ] }, { "name": "CCAAT-box-binding transcription factor", "type": "synonym", "evidence": [ { "id": "A0A1D5PEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Stimulates transcription from the HSP70 promoter.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1#function" }, { "database": "UniProtKB", "id": "ARBA00058879", "url": "https://www.uniprot.org/uniprotkb/ARBA00058879#function" }, { "database": "UniProtKB", "id": "A0A8V0XMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMN8#function" }, { "database": "UniProtKB", "id": "A0A8V0XMP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP4#function" }, { "database": "UniProtKB", "id": "A0A8V0XS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS02#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEBPZ", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1", "locus": { "chromosome": "3", "start_pos": 33195465, "end_pos": 33211113, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007090", "url": "https://www.ensembl.org/id/ENSGALG00010007090" } ] } } ], "crossref": [ { "id": "A0A1D5PEJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040335", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040335", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PEJ1", "url": "https://www.orthodb.org/?gene=A0A1D5PEJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMN8", "url": "https://www.orthodb.org/?gene=A0A8V0XMN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMP4", "url": "https://www.orthodb.org/?gene=A0A8V0XMP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XS02", "url": "https://www.orthodb.org/?gene=A0A8V0XS02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12048:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12048:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALGEWGVRRRPEEADGYELDEDDDDGDDGGDADGFTLDEVLRLGGTKQDFLMLCGVDEAEEMVDGGKKGAIDDLKEGELEAFIGSLGLGKYAKGCLDEEEEEEENEEKKGSKEKEKIPKKEKSKKEKSKEKSKKETVAPSSEGKKEKKTEEQVSSRKDSKKKLAGGGPRQQQSVQKERLEEDFTFRAREVILIKPGGKWYDLEYTGETSAEPQDPALLSQYKALAQKLYQHETELYKSKTEYQKGASSAWMKTVVSSGTLADRMAAMTLLIQDSAVHSLHFVENLVNLVKKKGSRQQSLMALDTFRELLLSDLLPDTRKLWSFSQRPFNNIEKMSSGNRDSRDRRLILWYFEHQLKLLVAEFVQTLEALSHDSLTATKTRALAAAHELLCNKPEQEKFLLVQLVNKLGDPQNKIATKASYLLETLLHKHPNMKGVVCSEVERLLYRTNISAKTQYYAMCFLNQIVLSHEETPLANKLITLYFCFFRNCIKKKDVESKMLSALLSGVNRAYPYAEIGDEKVKEQMNTLFKVLHLVNFSTSVQALMLLFQVMDSQQTVSDRYYAALYKKLLDPGLATCSKPSMFLNLVYKSLKADVVLRRVKAFVKRLLQVTTGQTPPFICGTLYLLSELLKVKPGLRVQLQDHVESDEEECFKDQEETEENEETFVDADKVEREERSATENSAKRNNLSSAASWVHHENMGGRKNGVSYDPLHRSPLYCGAESTSLWELKKLSEHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTSSVVMQRKKKQFMTDTQNLAVNSKEFLARDESKIPVDELFFHRFYTKFDKTREKHRRQEDEESVEDVDDDEFERALDTFEADGAVGVGQDDLDFAGNIKKKSNGNKKSKRSEESGADWEDSDDEEFSDLDDEEVSLGSMEEDDFEEDMDEEGGVFMDVSDDGNGPDLNNDNQSKSVSKKTKRKKDMNFMGSHEGSSQGKKRKLKDAKILAAAEEIGYLLDENAGSKFDNIGMNAMANRDNANIKQIKWELERDRWLHNRDVKSIIKRKKQLRHTGLKKKYRGKKSKR", "length": 1074, "header": "tr|A0A1D5PEJ1-1|A0A1D5PEJ1_CHICK Isoform 1 of CCAAT/enhancer-binding protein zeta OS=Gallus gallus OX=9031 GN=CEBPZ PE=1 SV=1 CANONICAL=A0A1D5PEJ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1/entry", "sequence": { "sequence": "MAALGEWGVRRRPEEADGYELDEDDDDGDDGGDADGFTLDEVLRLGGTKQDFLMLCGVDEAEEMVDGGKKGAIDDLKEGELEAFIGSLGLGKYAKGCLDEEEEEEENEEKKGSKEKEKIPKKEKSKKEKSKEKSKKETVAPSSEGKKEKKTEEQVSSRKDSKKKLAGGGPRQQQSVQKERLEEDFTFRAREVILIKPGGKWYDLEYTGETSAEPQDPALLSQYKALAQKLYQHETELYKSKTEYQKGASSAWMKTVVSSGTLADRMAAMTLLIQDSAVHSLHFVENLVNLVKKKGSRQQSLMALDTFRELLLSDLLPDTRKLWSFSQRPFNNIEKMSSGNRDSRDRRLILWYFEHQLKLLVAEFVQTLEALSHDSLTATKTRALAAAHELLCNKPEQEKFLLVQLVNKLGDPQNKIATKASYLLETLLHKHPNMKGVVCSEVERLLYRTNISAKTQYYAMCFLNQIVLSHEETPLANKLITLYFCFFRNCIKKKDVESKMLSALLSGVNRAYPYAEIGDEKVKEQMNTLFKVLHLVNFSTSVQALMLLFQVMDSQQTVSDRYYAALYKKLLDPGLATCSKPSMFLNLVYKSLKADVVLRRVKAFVKRLLQVTTGQTPPFICGTLYLLSELLKVKPGLRVQLQDHVESDEEECFKDQEETEENEETFVDADKVEREERSATENSAKRNNLSSAASWVHHENMGGRKNGVSYDPLHRSPLYCGAESTSLWELKKLSEHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTSSVVMQRKKKQFMTDTQNLAVNSKEFLARDESKIPVDELFFHRFYTKFDKTREKHRRQEDEESVEDVDDDEFERALDTFEADGAVGVGQDDLDFAGNIKKKSNGNKKSKRSEESGADWEDSDDEEFSDLDDEEVSLGSMEEDDFEEDMDEEGGVFMDVSDDGNGPDLNNDNQSKSVSKKTKRKKDMNFMGSHEGSSQGKKRKLKDAKILAAAEEIGYLLDENAGSKFDNIGMNAMANRDNANIKQIKWELERDRWLHNRDVKSIIKRKKQLRHTGLKKKYRGKKSKR", "length": 1074, "header": "tr|A0A1D5PEJ1-1|A0A1D5PEJ1_CHICK Isoform 1 of CCAAT/enhancer-binding protein zeta OS=Gallus gallus OX=9031 GN=CEBPZ PE=1 SV=1 CANONICAL=A0A1D5PEJ1-1" }, "locus": { "chromosome": "3", "start_pos": 33211073, "end_pos": 33195980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016841.1", "url": "https://www.ensembl.org/id/ENSGALT00010016841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009463.1", "url": "https://www.ensembl.org/id/ENSGALP00010009463.1" } ] } }, { "isoform_ac": "A0A8V0XMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMN8/entry", "sequence": { "sequence": "MAALGEWGVRRRPEEADGYELDEDDDDGDDGGDADGFTLDEVLRLGGTKQDFLMLCGVDEAEEMVDGGKKGAIDDLKEGELEAFIGSLGLGKYAKGCLDEEEEEEENEEKKGSKEKEKIPKKEKSKKEKSKEKSKKETVAPSSEGKKEKKTEEQVSSRKDSKKKLAGGGPRQQQSVQKERLEEDFTFRAREVILIKPGGKWYDLEYTGETSAEPQDPALLSQYKALAQKLYQHETELYKSKTEYQKGASSAWMKTVVSSGTLADRMAAMTLLIQDSAVHSLHFVENLVNLVKKKGSRQQSLMALDTFRELLLSDLLPDTRKLWSFSQRPFNNIEKMSSGNRDSRDRRLILWYFEHQLKLLVAEFVQTLEALSHDSLTATKTRALAAAHELLCNKPEQEKFLLVQLVNKLGDPQNKIATKASYLLETLLHKHPNMKGVVCSEVERLLYRTNISAKTQYYAMCFLNQIVLSHEETPLANKLITLYFCFFRNCIKKKDVESKMLSALLSGVNRAYPYAEIGDEKVKEQMNTLFKVLHLVNFSTSVQALMLLFQVMDSQQTVSDRYYAALYKKLLDPGLATCSKPSMFLNLVYKSLKADVVLRRVKAFVKRLLQVTTGQTPPFICGTLYLLSELLKVKPGLRVQLQDHVESDEEECFKDQEETEENEETFVDADKVEREERSATENSAKRNNLSSAASWVHHENMGGRKNGVSYDPLHRSPLYCGAESTSLWELKKLSEHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTSSVVMQRKKKQFMTDTQNLAVNSKEFLARDESKIPVDELFFHRFYTKFDKTREKHRRQEDEESVEDVDDDEFERALDTFEADGAVGVGQDDLDFAGNIKKKSNGNKKSKRSEESGADWEDSDDEEFSDLDDEEVSLGSMEEDDFEEDMDEEGGVFMDVSDDGNGPDLNNDNQSKSVSKKTKRKKDMNFMGSHEGKEVLFHLRRPNTNRQSGKIVTRRVQYSRFVDLDSDLNKLQKKRNWF", "length": 1027, "header": "tr|A0A8V0XMN8-1|A0A1D5PEJ1_CHICK Computationally mapped isoform of CCAAT/enhancer-binding protein zeta OS=Gallus gallus OX=9031 GN=CEBPZ PE=1 SV=1 CANONICAL=A0A1D5PEJ1-1" }, "locus": { "chromosome": "3", "start_pos": 33211073, "end_pos": 33197525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016836.1", "url": "https://www.ensembl.org/id/ENSGALT00010016836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009461.1", "url": "https://www.ensembl.org/id/ENSGALP00010009461.1" } ] } }, { "isoform_ac": "A0A8V0XMP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP4/entry", "sequence": { "sequence": "MAALGEWGVRRRPEEADGYELDEDDDDGDDGGDADGFTLDEVLRLGGTKQDFLMLCGVDEAEEMVDGGKKGAIDDLKEGELEAFIGSLGLGKYAKGCLDEEEEEEENEEKKGSKEKEKIPKKEKSKKEKSKEKSKKETVAPSSEGKKEKKTEEQVSSRKDSKKKLAGGGPRQQQSVQKERLEEDFTFRAREVILIKPGGKWYDLEYTGETSAEPQDPALLSQYKALAQKLYQHETELYKSKTEYQKGASSAWMKTVVSSGTLADRMAAMTLLIQDSAVHSLHFVENLVNLVKKKGSRQQSLMALDTFRELLLSDLLPDTRKLWSFSQRPFNNIEKMSSGNRDSRDRRLILWYFEHQLKLLVAEFVQTLEALSHDSLTATKTRALAAAHELLCNKPEQEKFLLVQLVNKLGDPQNKIATKASYLLETLLHKHPNMKGVVCSEVERLLYRTNISAKTQYYAMCFLNQIVLSHEETPLANKLITLYFCFFRNCIKKKDVESKMLSALLSGVNRAYPYAEIGDEKVKEQMNTLFKVLHLVNFSTSVQALMLLFQVMDSQQTVSDRYYAALYKKLLDPGLATCSKPSMFLNLVYKSLKADVVLRRVKAFVKRLLQVTTGQTPPFICGTLYLLSELLKVKPGLRVQLQDHVESDEEECFKDQEETEENEETFVDADKVEREERSATENSAKRNNLSSAASWVHHENMGGRKNGVSYDPLHRSPLYCGAESTSLWELKKKQFMTDTQNLAVNSKEFLARDESKIPVDELFFHRFYTKFDKTREKHRRQEDEESVEDVDDDEFERALDTFEADGAVGVGQDDLDFAGNIKKKSNGNKKSKRSEESGADWEDSDDEEFSDLDDEEVSLGSMEEDDFEEDMDEEGGVFMDVSDDGNGPDLNNDNQSKSVSKKTKRKKDMNFMGSHEGSSQGKKRKLKDAKILAAAEEIGYLLDENAGSKFDNIGMNAMANRDNANIKQIKWELERDRWLHNRDVKSIIKRKKQLRHTGLKKKYRGKKSKR", "length": 1010, "header": "tr|A0A8V0XMP4-1|A0A1D5PEJ1_CHICK Computationally mapped isoform of CCAAT/enhancer-binding protein zeta OS=Gallus gallus OX=9031 GN=CEBPZ PE=1 SV=1 CANONICAL=A0A1D5PEJ1-1" }, "locus": { "chromosome": "3", "start_pos": 33211073, "end_pos": 33195980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016848.1", "url": "https://www.ensembl.org/id/ENSGALT00010016848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009466.1", "url": "https://www.ensembl.org/id/ENSGALP00010009466.1" } ] } }, { "isoform_ac": "A0A8V0XS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS02/entry", "sequence": { "sequence": "MAALGEWGVRRRPEEADGYELDEDDDDGDDGGDADGFTLDEVLRLGGTKQDFLMLCGVDEAEEMVDGGKKGAIDDLKEGELEAFIGSLGLGKYAKGCLDEEEEEEENEEKKGSKEKEKIPKKEKSKKEKSKEKSKKETVAPSSEGKKEKKTEEQVSSRKDSKKKLAGGGPRQQQSVQKERLEEDFTFRAREVILIKPGGKWYDLEYTGETSAEPQDPALLSQYKALAQKLYQHETELYKSKTEYQKGASSAWMKTVVSSGTLADRMAAMTLLIQDSAVHSLHFVENLVNLVKKKGSRQQSLMALDTFRELLLSDLLPDTRKLWSFSQRPFNNIEKMSSGNRDSRDRRLILWYFEHQLKLLVAEFVQTLEALSHDSLTATKTRALAAAHELLCNKPEQEKFLLVQLVNKLGDPQNKIATKASYLLETLLHKHPNMKGVVCSEVERLLYRTNISAKTQYYAMCFLNQIVLSHEETPLANKLITLYFCFFRNCIKKKDVESKMLSALLSGVNRAYPYAEIGDEKVKEQMNTLFKVLHLVNFSTSVQALMLLFQVMDSQQTVSDRYYAALYKKLLDPGLATCSKPSMFLNLVYKSLKADVVLRRVKAFVKRLLQVTTGQTPPFICGTLYLLSELLKVKPGLRVQLQDHVESDEEECFKDQEETEENEETFVDADKVEREERSATENSAKRNNLSSAASWVHHENMGGRKNGVSYDPLHRSPLYCGAESTSLWELKKVKHSPITACCTTNIFLFQGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENTSSVVMQRKKKQFMTDTQNLAVNSKEFLARDESKIPVDELFFHRFYTKFDKTREKHRRQEDEESVEDVDDDEFERALDTFEADGAVGVGQDDLDFAGNIKKKSNGNKKSKRSEESGADWEDSDDEEFSDLDDEEVSLGSMEEDDFEEDMDEEGGVFMDVSDDGNGPDLNNDNQSKSVSKKTKRKKDMNFMGSHEGSSQGKKRKLKDAKILAAAEEIGYLLDENAGSKFDNIGMNAMANRDNANIKQIKWELERDRWLHNRDVKSIIKRKKQLRHTGLKKKYRGKKSKR", "length": 1074, "header": "tr|A0A8V0XS02-1|A0A1D5PEJ1_CHICK Computationally mapped isoform of CCAAT/enhancer-binding protein zeta OS=Gallus gallus OX=9031 GN=CEBPZ PE=1 SV=1 CANONICAL=A0A1D5PEJ1-1" }, "locus": { "chromosome": "3", "start_pos": 33211073, "end_pos": 33195980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016844.1", "url": "https://www.ensembl.org/id/ENSGALT00010016844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009465.1", "url": "https://www.ensembl.org/id/ENSGALP00010009465.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PEJ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1074, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PEJ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEJ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEJ1" }, { "id": "PF03914", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCAAT-binding factor", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 745, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 450, "end_pos": 452 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 786, "end_pos": 788 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PEK9-1", "uniprot_ac": "A0A1D5PEK9", "uniprot_id": "A0A1D5PEK9_CHICK", "mass": { "chemical_mass": 33768.0, "monoisotopic_mass": 33768.0 }, "refseq": { "ac": "XP_004939806", "name": "leucine-rich repeat-containing protein 30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939806" }, "gene_names": [ { "name": "LRRC30", "type": "recommended", "evidence": [ { "id": "A0A1D5PEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9" } ] }, { "name": "LRRC30", "type": "synonym", "evidence": [ { "id": "XP_004939806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939806" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 30", "type": "synonym", "evidence": [ { "id": "A0A1D5PEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 30", "type": "synonym", "evidence": [ { "id": "XP_004939806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939806" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939806" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEK9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC30", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9", "locus": {} } ], "crossref": [ { "id": "A0A1D5PEK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042652", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769685", "url": "https://www.ncbi.nlm.nih.gov/gene/769685", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769685", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769685", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVQIPLC", "url": "https://omabrowser.org/oma/group/FVQIPLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PEK9", "url": "https://www.orthodb.org/?gene=A0A1D5PEK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004939806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939806", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PEK9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTKHSKNEGRRSMLFLRKSSKLPAWEDALLSGKDPKSLLKRGLHYISLSLIMKGMTSAPDFLWGLPEVQKLNLSRNQLVAISPSLGKLDRLVVLNLGGNRLKCLPKEIGLLRNLKVLFVNMNCLTEVPAELSLCRKLEVLSLSHNCISQLPSSFTDLTSLKKLNLSNNRFVQIPLCIFALRSLDFLHLGSNRLENIAESVQYLVNLQIFIVENNNIRTLPRSLCFITALELLNVDYNSIQTLPDDLYLLRRLPRIAWNPMDKGLHISHNPLSRPLPEIVEGGLDALFNYLKEKKEHN", "length": 298, "header": "tr|A0A1D5PEK9-1|A0A1D5PEK9_CHICK Isoform 1 of Leucine rich repeat containing 30 OS=Gallus gallus OX=9031 GN=LRRC30 PE=4 SV=2 CANONICAL=A0A1D5PEK9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9/entry", "sequence": { "sequence": "MGTKHSKNEGRRSMLFLRKSSKLPAWEDALLSGKDPKSLLKRGLHYISLSLIMKGMTSAPDFLWGLPEVQKLNLSRNQLVAISPSLGKLDRLVVLNLGGNRLKCLPKEIGLLRNLKVLFVNMNCLTEVPAELSLCRKLEVLSLSHNCISQLPSSFTDLTSLKKLNLSNNRFVQIPLCIFALRSLDFLHLGSNRLENIAESVQYLVNLQIFIVENNNIRTLPRSLCFITALELLNVDYNSIQTLPDDLYLLRRLPRIAWNPMDKGLHISHNPLSRPLPEIVEGGLDALFNYLKEKKEHN", "length": 298, "header": "tr|A0A1D5PEK9-1|A0A1D5PEK9_CHICK Isoform 1 of Leucine rich repeat containing 30 OS=Gallus gallus OX=9031 GN=LRRC30 PE=4 SV=2 CANONICAL=A0A1D5PEK9-1" }, "locus": { "chromosome": "2", "start_pos": 99118855, "end_pos": 99117962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004582.1", "url": "https://www.ensembl.org/id/ENSGALT00010004582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002788.1", "url": "https://www.ensembl.org/id/ENSGALP00010002788.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769685", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769685", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NM36-1", "protein_name": "Leucine-rich repeat-containing protein 30", "gene_name": "LRRC30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGARQSRASSKDKGPKRMLFTGRRQKFSPWDDALLSGRDPRSLLKRGMHHVSFSLVTRGMTDIPDFLWGLSEVQKLNLSHNQLRVLPPEVGKLTRIVVLNLCGNRLKSLPREVSLLQCLKVLFVNMNCLTEVPAELSLCRKLEVLSLSHNCLSQLPACFADLSRLRKLNLSNNFFAHIPMCVFSLKELIFLHVGSNRLENIAESIQHLASLQIFIAEGNNIHSFPRSLCLVTSLELLNLNNNDIQTLPSELHLLCRLVRIAWNPMDKGLHISHNPLSKPLPELVEGGLEMLFGYLKDKKHT", "length": 301 }, "evidence": [ { "id": "A0A1D5PEK9", "url": "https://omabrowser.org/oma/group/A0A1D5PEK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZWX6-1", "protein_name": "Leucine-rich repeat-containing protein 30", "gene_name": "Lrrc30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVKQSRASSDDKDPKRFLVGKRQKFSSWDDTLLLGKDPRSLLKRGMRHVSFSLVTKGMTDIPDFLWGLLEVQKLNLSHNQLRVLPPEVGRLTRIVVLNLCGNCLKSLPKEVSLLQSLKVLFLNMNCLAEVPAELSLCRNLEVLSMSHNCLSQLPASFADLARLRKLNLSNNYFAHIPLCVFSLKELDFLHVGSNRLENIAESIQCLASLQIFIAESNNIHSFPRSLCLVTSLELLNLNNNDIQTLPDELYLLCRLGRIAWNPMDKGLHISHNPLSKPLPELVEGGLEMLYSYLKDKKHN", "length": 300 }, "evidence": [ { "id": "A0A1D5PEK9", "url": "https://omabrowser.org/oma/group/A0A1D5PEK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HIV2-1", "protein_name": "Leucine-rich repeat-containing protein 30", "gene_name": "Lrrc30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGTKQSRVSSKDKDPKRLLLGKRQKFSSWDDALLLGKDPRSLLKRGMRHVSFSLVTKGMTDIPDFLWGLLEVQKLNLSHNQLRVLPPEVGRLTRIVVLNLCGNQLKSLPREVSLLQNLKVLFLNMNCLAEVPAELSLCRNLEVLSMSHNCLSQLPGSFADLSRLRKLNLSNNSFAHIPICVFSLKELDFLHVGANRLENIAESIQCLAGLQIFIAESNNIHSFPRSLCLVTSLELLNLNNNDIQTLPDELYLLCRLGRIAWNPMDKGLHISHNPLSKPLPELVEGGLEMLYSYLKDKKHN", "length": 300 }, "evidence": [ { "id": "A0A1D5PEK9", "url": "https://omabrowser.org/oma/group/A0A1D5PEK9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LGV9-1", "protein_name": "Leucine-rich repeat-containing protein 30", "gene_name": "LRRC30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGARQSGACCKDKGLPGPGPLRGRQKFSPWDEALLPGRDPRCLLKRGLRHVSFSLVTTGMTDAPDFLWGLSEVQKLNLSHNQLRALPPDVGRLTRLVVLNLCGNRLKSLPRELSLLRSLKVLFLHMNCLTELPAELSACQSLEVLGLSHNCLSQLPASFADLARLRKLNLSHNRFAHIPVCVFALKELDFLHVGSNRLENIAESIQCLASLQIFIAESNNIHAFPRALCLLTSLELLNLNNNNIQTLPEELYLLCRLARIAWNPMDKGLHISRNPLSKPLPELLEGGLEMLFGYLKDKKHT", "length": 301 }, "evidence": [ { "id": "A0A1D5PEK9", "url": "https://omabrowser.org/oma/group/A0A1D5PEK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O64566-1", "protein_name": "Plant intracellular Ras-group-related LRR protein 6", "gene_name": "PIRL6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MICEEAYHQQPQIQKEQMMTMDQRNNHQRKRSPLSSPSSPSSPSSPSSPKSPSFNNNEEERLEVVNLSGMALESLPNPSLNLAQICKLDLSNNHLQTIPESLTARLLNLIALDVHSNQIKALPNSIGCLSKLKTLNVSGNFLVSFPKSIQHCRSLEELNANFNKLIRLPDSIGFELTNLRKLSINSNKLISLPISITHLTSLRVLDARLNCLMILPDDLENLINLEILNVSQNFQYLSALPSSIGLLMNLIELDVSYNKITVLPESIGCMRRLRKLSVEGNPLVSPPIEVMEQNLQVVREYLTQKMNGGSPRSPSKKKSWGFGKLVKYGTFNGGSRSWNREEREGFIMPEYRSIDSLASPRYSGMFSPRRLFSPRTYFSR", "length": 380 }, "evidence": [ { "id": "A0A1D5PEK9", "url": "https://omabrowser.org/oma/group/A0A1D5PEK9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEK9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PEK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 298, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PEK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PEK9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PEM8-1", "uniprot_ac": "A0A1D5PEM8", "uniprot_id": "A0A1D5PEM8_CHICK", "mass": { "chemical_mass": 218675.0, "monoisotopic_mass": 218675.0 }, "refseq": {}, "gene_names": [ { "name": "SBF1", "type": "recommended", "evidence": [ { "id": "A0A1D5PEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ] } ], "protein_names": [ { "name": "SET binding factor 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SBF1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8", "locus": { "chromosome": "1", "start_pos": 1119149, "end_pos": 1184682, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006372", "url": "https://www.ensembl.org/id/ENSGALG00010006372" } ] } } ], "crossref": [ { "id": "ENSGALG00000043178", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043178", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14588", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14588", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSZ3", "url": "https://www.orthodb.org/?gene=A0A1D5PSZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQI1", "url": "https://www.orthodb.org/?gene=A0A8V0XQI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVB0", "url": "https://www.orthodb.org/?gene=A0A8V0XVB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVC6", "url": "https://www.orthodb.org/?gene=A0A8V0XVC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVD2", "url": "https://www.orthodb.org/?gene=A0A8V0XVD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY64", "url": "https://www.orthodb.org/?gene=A0A8V0XY64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483248", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483248", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLSSQQVTDMFQGLTVGVMSLGHLGHSTTTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSADFSDKRQPKLGSLMKQVMGGKDEGPGTISRGGLGHRARVITLSTPKCVSPKGRESPRGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1939, "header": "tr|A0A1D5PEM8-1|A0A1D5PEM8_CHICK Isoform 1 of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=2 CANONICAL=A0A1D5PEM8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8/entry", "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLSSQQVTDMFQGLTVGVMSLGHLGHSTTTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSADFSDKRQPKLGSLMKQVMGGKDEGPGTISRGGLGHRARVITLSTPKCVSPKGRESPRGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1939, "header": "tr|A0A1D5PEM8-1|A0A1D5PEM8_CHICK Isoform 1 of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=2 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1177804, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015220.1", "url": "https://www.ensembl.org/id/ENSGALT00010015220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008943.1", "url": "https://www.ensembl.org/id/ENSGALP00010008943.1" } ] } }, { "isoform_ac": "A0A1D5PSZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSZ3/entry", "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSADFSDKRQPKLGSLMKQVMGGKDEGPGTISRGGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1887, "header": "tr|A0A1D5PSZ3-1|A0A1D5PSZ3_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=2 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1177804, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015230.1", "url": "https://www.ensembl.org/id/ENSGALT00010015230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008946.1", "url": "https://www.ensembl.org/id/ENSGALP00010008946.1" } ] } }, { "isoform_ac": "A0A8V0XQI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQI1/entry", "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSAGLGHRARVITLSTPKCVSPKGRESPRGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1882, "header": "tr|A0A8V0XQI1-1|A0A1D5PEM8_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=1 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1177804, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015243.1", "url": "https://www.ensembl.org/id/ENSGALT00010015243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008952.1", "url": "https://www.ensembl.org/id/ENSGALP00010008952.1" } ] } }, { "isoform_ac": "A0A8V0XVB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB0/entry", "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQPDADDEAVRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSAGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1864, "header": "tr|A0A8V0XVB0-1|A0A1D5PEM8_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=1 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1177804, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015217.1", "url": "https://www.ensembl.org/id/ENSGALT00010015217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008941.1", "url": "https://www.ensembl.org/id/ENSGALP00010008941.1" } ] } }, { "isoform_ac": "A0A8V0XVC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVC6/entry", "sequence": { "sequence": "MARLADYFVLVGYDAEKRGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSAGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1856, "header": "tr|A0A8V0XVC6-1|A0A1D5PEM8_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=1 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1177804, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015252.1", "url": "https://www.ensembl.org/id/ENSGALT00010015252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008956.1", "url": "https://www.ensembl.org/id/ENSGALP00010008956.1" } ] } }, { "isoform_ac": "A0A8V0XVD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVD2/entry", "sequence": { "sequence": "MGVPVAPRVPPISAPEGREVEESMRRVGEHRNTALERCQPPPGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSADFSDKRQPKLGSLMKQVMGGKDEGPGTISRGGLGHRARVITLSTPKCVSPKGRESPRGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1937, "header": "tr|A0A8V0XVD2-1|A0A1D5PEM8_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=1 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1180109, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015267.1", "url": "https://www.ensembl.org/id/ENSGALT00010015267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008961.1", "url": "https://www.ensembl.org/id/ENSGALP00010008961.1" } ] } }, { "isoform_ac": "A0A8V0XY64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY64/entry", "sequence": { "sequence": "MGVPVAPRVPPISAPEGREESMRRVGEHRNTALERCQPPPGSGDGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLFTERNPPTFFVAVLTDINSERHYCACFTFWEAVESTQPQSHPRNGEEEEEESASPVQPAQLFAPKSLVLVSRLDHAEVFRNSLGLIYTIYVDGLNVSLENVIGNLLTCTIPITGGAQRTISLGAGDRQVIQTPINDSLPVSSCSVALLFRQLGITNVLYLFCAALTEHKILFLSSSYQRLTDACRALLALMFPLKYSFTYVPILPAQLLEVLSTPTPFIIGVHSIFQSETQELLDVVIADLDGGTVNVPECVHISLLPEPLLQQTREALSMVLDPELEVADLAFPPSTISASSLKMQDKEIRAVFLRLFAQLLQGYRWCLHIIRIHPEPVIRFHKAAFLGQRGLTEDDFLTKVLEGMAFAGFVTERGAPYRSIDLFDELVAYEVKRMRAEEGNKQKILRHIKELAEKLYKNENPYPAVTMHKVQKPTEGCHLRLHQKPFPRLDEGTVQWIIDQATAKLQTAPPAVKAEKKCMVPSGPPIAAIMERNGNALANSARRLEVVRNCISYVFENKMLEAKKLFPAVLRAMKGRAARHCLTQELNLHVQQNRAVLDHQQFDFIVRMMNCCLQDCTAMDEHGIAAALLPLVTAFCRKLSPGITQFAYSCVQEHVVWTNIQFWEAMFYSDVQNHIRALYLDSSEENHADEESTEEPQEARSALEIASEQLRLWPTMSREKQQELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRSSGLGDVESVSNSFVTNSIAGSVAESYDTESGFEDAESSDVANYVVRFINRFVDKVCTESGVTNEHLKGLHVMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPNLLVGEECVMEGLRVYLMPDGREEAAGGNIGGPPLLPAEGAIFLTTYRIIFKGTPTDPLVGEQVVIRSFPISSLTKEKKINIQAQVDQFIQEGLQLRSCTFQLLKIAFDEEVASDSAEVFRKHLHKLRYPQHVHGTFAFTVGQSPKQAMQPKAKEKNPSLRTLSKNLVKNAKKTIGRQYVTRKKYTPPAWEQRSSQHFPEDNEDEISVSEEMDRSTLTPTTTIRPSEKMTINHLVERACCRDYQRLGLGTLSSSLTRSKNEPFRISTVNRMYAICRSYPGLLIVPQSIQDNTIQRISRCYRQNRFPVVCWRNSRTKAVLLRSGGLHGKGVVGLFKSQNAPTAGPSQTDSTSLEQEKYLQAVINSMPHYADAGGRNTLSGFTSAHMSSADFSDKRQPKLGSLMKQVMGGKDEGPGTISRGGLGHRARVITLSTPKCVSPKGRESPRGKWGSIRASGRMSSYALNVEIGSRLAGKDLLGAQHNGAPAEASFLRQHRASLYIIGDKSQLKGVKPDPLQHWEVVPIEVFDVRQVKASFKKLMKACVPGCPSTDPSVAYLRSLEESEWLSQIHKILQISVLVVELLDTGSSVLVSLEDGWDITTQVVSLVQLLSDPYYRTLEGFRLLVEKEWLSFGHRFSHRGAQTLAGQSSGFAPIFLQFLDCVHQIHLQFPMEFEFSLYYLKFLSYHYISNRFRTFLLDSDYERIELGLLYEEKGERKCQQVYKSIWDYIDRLNKKAPIFFNYMYAPEDGEVLRPYSNISNLKVWDYYTEETLSEGPSYDWELVQGQPEHMEEADRQDTSAPQTKRKIIWPCYDNRSRMEPDAISKLLEDLHNLEMELGQVPERWKDTWDKIKASQRTEARQEGSRTPSSLLMSSGLSHHRRSLGMYLQESGVGSTLNLSLDSDTSSTSTPSSGKQGGRRSTSTLYNQFQMSESENRSYEGSLYKKGAFMKPWKPRWFVLDKTKHQLRYYDSRMDTECKGVIDLAEVESITPGTPTMGAPKTVDEKAFFDLKTTKRVYNFCAQDVQLAQQWIDRIQSCLSDA", "length": 1935, "header": "tr|A0A8V0XY64-1|A0A1D5PEM8_CHICK Computationally mapped isoform of SET binding factor 1 OS=Gallus gallus OX=9031 GN=SBF1 PE=1 SV=1 CANONICAL=A0A1D5PEM8-1" }, "locus": { "chromosome": "1", "start_pos": 1180109, "end_pos": 1120275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015259.1", "url": "https://www.ensembl.org/id/ENSGALT00010015259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008959.1", "url": "https://www.ensembl.org/id/ENSGALP00010008959.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1807, "start_aa": "Thr", "end_pos": 1807, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1807", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1483248", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483248", "resource": "Reactome", "description": "Synthesis of PIPs at the ER membrane" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PEM8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1655, "end_pos": 1657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1712, "end_pos": 1714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1795, "end_pos": 1797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1833, "end_pos": 1835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1807 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 1655, "end_pos": 1657 }, { "start_pos": 1712, "end_pos": 1714 }, { "start_pos": 1795, "end_pos": 1797 }, { "start_pos": 1833, "end_pos": 1835 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PF73-1", "uniprot_ac": "A0A1D5PF73", "uniprot_id": "A0A1D5PF73_CHICK", "mass": { "chemical_mass": 11008.0, "monoisotopic_mass": 11008.0 }, "refseq": { "ac": "XP_040548176", "name": "feather keratin 3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548176" }, "gene_names": [ { "name": "LOC121107669", "type": "recommended", "evidence": [ { "id": "A0A1D5PF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73" } ] }, { "name": "LOC121107669", "type": "synonym", "evidence": [ { "id": "XP_040548176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548176" } ] }, { "name": "LOC121107670", "type": "synonym", "evidence": [ { "id": "A0A1D5PF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A1D5PF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73/entry#names_and_taxonomy" } ] }, { "name": "feather keratin 3-like", "type": "synonym", "evidence": [ { "id": "XP_040548176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548176" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040548176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548176" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PF73", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121107669", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73", "locus": {} } ], "crossref": [ { "id": "121107669", "url": "https://www.ncbi.nlm.nih.gov/gene/121107669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858100", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTRCYRT", "url": "https://omabrowser.org/oma/group/PTRCYRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PF73", "url": "https://www.orthodb.org/?gene=A0A1D5PF73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040548176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548176", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PF73", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PF73-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDQCLPRLQCRPCGPTPLANSCNESCVRQCQDSNVFIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSSEGVPISSGGFGGFGLSGFGSRLCGRRCFPC", "length": 107, "header": "tr|A0A1D5PF73-1|A0A1D5PF73_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107669 PE=3 SV=1 CANONICAL=A0A1D5PF73-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PF73-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PF73/entry", "sequence": { "sequence": "MSCYDQCLPRLQCRPCGPTPLANSCNESCVRQCQDSNVFIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSSEGVPISSGGFGGFGLSGFGSRLCGRRCFPC", "length": 107, "header": "tr|A0A1D5PF73-1|A0A1D5PF73_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107669 PE=3 SV=1 CANONICAL=A0A1D5PF73-1" }, "locus": { "chromosome": "27", "start_pos": 559874, "end_pos": 559554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062879.1", "url": "https://www.ensembl.org/id/ENSGALT00010062879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038834.1", "url": "https://www.ensembl.org/id/ENSGALP00010038834.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": 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}, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 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"evidence": [ { "id": "A0A1D5PFB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 5B", "type": "synonym", "evidence": [ { "id": "XP_025003755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003755" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003755" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC5B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1", "locus": { "chromosome": "2", "start_pos": 114662271, "end_pos": 114622671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004050", "url": "https://www.ensembl.org/id/ENSGALG00010004050" } ] } } ], "crossref": [ { "id": "A0A1D5PFB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030660", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428358", "url": "https://www.ncbi.nlm.nih.gov/gene/428358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051434", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051434", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428358", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EINKAHT", "url": "https://omabrowser.org/oma/group/EINKAHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFB1", "url": "https://www.orthodb.org/?gene=A0A1D5PFB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44027:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44027:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025003755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQRQRALSTSGEALYGILALEKGATHDEIKKSYRKLALKYHPDKNPDNPEAAEKFKEINNAHATLTDLSKRNIYDKYGSLGLYVAEQFGEENVNTYFMLSSWWAKGLFAVCGLLTGCYLCCCLCCCFNCCCGKCKPKAPEGEEQEFCVSPEDLEEQIKNDMERDGETPIVLQPTNATEKTQLIGDSHRSYRTDS", "length": 196, "header": "tr|A0A1D5PFB1-1|A0A1D5PFB1_CHICK Isoform 1 of DnaJ homolog subfamily C member 5B OS=Gallus gallus OX=9031 GN=DNAJC5B PE=4 SV=1 CANONICAL=A0A1D5PFB1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1/entry", "sequence": { "sequence": "MAEQRQRALSTSGEALYGILALEKGATHDEIKKSYRKLALKYHPDKNPDNPEAAEKFKEINNAHATLTDLSKRNIYDKYGSLGLYVAEQFGEENVNTYFMLSSWWAKGLFAVCGLLTGCYLCCCLCCCFNCCCGKCKPKAPEGEEQEFCVSPEDLEEQIKNDMERDGETPIVLQPTNATEKTQLIGDSHRSYRTDS", "length": 196, "header": "tr|A0A1D5PFB1-1|A0A1D5PFB1_CHICK Isoform 1 of DnaJ homolog subfamily C member 5B OS=Gallus gallus OX=9031 GN=DNAJC5B PE=4 SV=1 CANONICAL=A0A1D5PFB1-1" }, "locus": { "chromosome": "2", "start_pos": 114659712, "end_pos": 114624965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009382.1", "url": "https://www.ensembl.org/id/ENSGALT00010009382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005545.1", "url": "https://www.ensembl.org/id/ENSGALP00010005545.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428358", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428358", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZD82-1", "protein_name": "DnaJ homolog subfamily C member 5B", "gene_name": "Dnajc5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACNIPNQRQRAMSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDNSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCCLCCCCNCCCGHCRPKTSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGSRSYCTDS", "length": 199 }, "evidence": [ { "id": "A0A1D5PFB1", "url": "https://omabrowser.org/oma/group/A0A1D5PFB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIJ8-1", "protein_name": "DnaJ homolog subfamily C member 5B", "gene_name": "DNAJC5B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACNIPNQRQRTMSTSGKALYEILGLHKGASNEEIKKTYRKLALKHHPDKNPDDPGAAEKFKEINNAHTILTDMSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFVIIGLLTGCYFCCCLCCCCNCCCGRCWTKSSMPEEDFYVSPEDLEEQIKTDIAKDMDFPVVLQPTNANEKTQLIREEPRSYCTDS", "length": 199 }, "evidence": [ { "id": "A0A1D5PFB1", "url": "https://omabrowser.org/oma/group/A0A1D5PFB1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQ94-1", "protein_name": "DnaJ homolog subfamily C member 5B", "gene_name": "Dnajc5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACNAPNQRQRTLSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCCLCCCCNCCCGHCRPKSSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGSRSYCTDS", "length": 199 }, "evidence": [ { "id": "A0A1D5PFB1", "url": "https://omabrowser.org/oma/group/A0A1D5PFB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UF47-1", "protein_name": "DnaJ homolog subfamily C member 5B", "gene_name": "DNAJC5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACNIPNQRQRTLSTTGEALYEILGLHKGASNEEIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKALFVIVGLLTGCYFCCCLCCCCNCCCGHCRPESSVPEEDFYVSPEDLEEQIKSDMEKDVDFPVFLQPTNANEKTQLIKEGSRSYCTDS", "length": 199 }, "evidence": [ { "id": "A0A1D5PFB1", "url": "https://omabrowser.org/oma/group/A0A1D5PFB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFB1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFG0-1", "uniprot_ac": "A0A1D5PFG0", "uniprot_id": "A0A1D5PFG0_CHICK", "mass": { "chemical_mass": 9302.0, "monoisotopic_mass": 9302.0 }, "refseq": { "ac": "NP_001289073", "name": "A-kinase anchoring protein 19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289073" }, "gene_names": [ { "name": "C2orf88", "type": "recommended", "evidence": [ { "id": "A0A1D5PFG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0" } ] }, { "name": "C2orf88", "type": "synonym", "evidence": [ { 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The reference sequence was derived from BM487021.1. On Oct 2, 2014 this sequence version replaced XP_004942450.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289073" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C2orf88", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0", "locus": { "chromosome": "7", "start_pos": 279938, "end_pos": 284135, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012838", "url": "https://www.ensembl.org/id/ENSGALG00010012838" } ] } } ], "crossref": [ { "id": "A0A1D5PFG0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033017", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033017", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857703", "url": "https://www.ncbi.nlm.nih.gov/gene/100857703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857703", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTFPFPN", "url": "https://omabrowser.org/oma/group/QTFPFPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFG0", "url": "https://www.orthodb.org/?gene=A0A1D5PFG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36471", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36471", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36471:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36471:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCIKSKDAFAGSNAIRVEGSREGDEGCTGEKSSLIAGMADEKGPSSAIVLDYAHRLSHEILDQAVKQWAVTESKYSDIPFIESDVP", "length": 87, "header": "tr|A0A1D5PFG0-1|A0A1D5PFG0_CHICK Isoform 1 of A-kinase anchoring protein 19 OS=Gallus gallus OX=9031 GN=C2orf88 PE=3 SV=1 CANONICAL=A0A1D5PFG0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0/entry", "sequence": { "sequence": "MGCIKSKDAFAGSNAIRVEGSREGDEGCTGEKSSLIAGMADEKGPSSAIVLDYAHRLSHEILDQAVKQWAVTESKYSDIPFIESDVP", "length": 87, "header": "tr|A0A1D5PFG0-1|A0A1D5PFG0_CHICK Isoform 1 of A-kinase anchoring protein 19 OS=Gallus gallus OX=9031 GN=C2orf88 PE=3 SV=1 CANONICAL=A0A1D5PFG0-1" }, "locus": { "chromosome": "7", "start_pos": 280403, "end_pos": 280143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030786.1", "url": "https://www.ensembl.org/id/ENSGALT00010030786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017857.1", "url": "https://www.ensembl.org/id/ENSGALP00010017857.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857703", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABE0-1", "protein_name": "A-kinase anchoring protein 19", "gene_name": "C2orf88", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCMKSKQTFPFSTTIESEKRPASQESFMPEERFLPRIPSLVNIKEEVKEPPGPEIVVSEFAHRLSQEILTDALQQWAGNNIKYYDIPYIESDGP", "length": 95 }, "evidence": [ { "id": "A0A1D5PFG0", "url": "https://omabrowser.org/oma/group/A0A1D5PFG0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C8S0-1", "protein_name": "A-kinase anchoring protein 19", "gene_name": "akap19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCMKSKRRDPTQNSDSSEKVDGKPGKHGEKAVLVFSEIGSMEDSVRINPVLLDYAQRLSEEIVARAVQQWAEVDSRYSDIPYIECDVP", "length": 89 }, "evidence": [ { "id": "A0A1D5PFG0", "url": "https://omabrowser.org/oma/group/A0A1D5PFG0/", "database": "OMA" } ], "glygen_name": 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"name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFG0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 87, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFG6-1", "uniprot_ac": "A0A1D5PFG6", "uniprot_id": "A0A1D5PFG6_CHICK", "mass": { "chemical_mass": 35781.0, "monoisotopic_mass": 35781.0 }, "refseq": { "ac": "XP_015133392", "name": "transmembrane protein 255B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133392" }, "gene_names": [ { "name": "TMEM255B", "type": "recommended", "evidence": [ { "id": "A0A1D5PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6" } ] }, { "name": "TMEM255B", "type": "synonym", "evidence": [ { "id": "XP_015133392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133392" } ] } ], "protein_names": [ { "name": "Transmembrane protein 255B", "type": "synonym", "evidence": [ { "id": "A0A1D5PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 255B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015133392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM255B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6", "locus": { "chromosome": "1", "start_pos": 137222999, "end_pos": 137286076, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014414", "url": "https://www.ensembl.org/id/ENSGALG00010014414" } ] } } ], "crossref": [ { "id": "A0A1D5PFG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035839", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035839", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418738", "url": "https://www.ncbi.nlm.nih.gov/gene/418738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418738", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418738", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHYYEFT", "url": "https://omabrowser.org/oma/group/SHYYEFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFG6", "url": "https://www.orthodb.org/?gene=A0A1D5PFG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNX8", "url": "https://www.orthodb.org/?gene=A0A8V0YNX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015133392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAPATAPAVAGPLALLDPTGQFAKRKKTSLWFTVSLLVVSIFILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIVGIHLVENRRQMLVASIVFISFGVVAAFCCAIVDGVFAARHIEPRPLYNRRCQFYSSGVGFLYDAYQTEVTCYTLNTKCQLKVKSNTCYCCDLYNCENSEQSSSYYEFLGVSSCQDVVHLYRLLWSSTVLNIIGLFLGIITAAILGAFKDMVPMSHIAFSSAPPPQILYNPAQQILTYAGFCPSAATISAYPSYPLPLQPASNFPGTSSTDISLSEETQPPSQSSSSYGLPPNAPPLYAPTYFLPGEKPPPYAP", "length": 331, "header": "tr|A0A1D5PFG6-1|A0A1D5PFG6_CHICK Isoform 1 of Transmembrane protein 255B OS=Gallus gallus OX=9031 GN=TMEM255B PE=3 SV=3 CANONICAL=A0A1D5PFG6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6/entry", "sequence": { "sequence": "MMAPATAPAVAGPLALLDPTGQFAKRKKTSLWFTVSLLVVSIFILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIVGIHLVENRRQMLVASIVFISFGVVAAFCCAIVDGVFAARHIEPRPLYNRRCQFYSSGVGFLYDAYQTEVTCYTLNTKCQLKVKSNTCYCCDLYNCENSEQSSSYYEFLGVSSCQDVVHLYRLLWSSTVLNIIGLFLGIITAAILGAFKDMVPMSHIAFSSAPPPQILYNPAQQILTYAGFCPSAATISAYPSYPLPLQPASNFPGTSSTDISLSEETQPPSQSSSSYGLPPNAPPLYAPTYFLPGEKPPPYAP", "length": 331, "header": "tr|A0A1D5PFG6-1|A0A1D5PFG6_CHICK Isoform 1 of Transmembrane protein 255B OS=Gallus gallus OX=9031 GN=TMEM255B PE=3 SV=3 CANONICAL=A0A1D5PFG6-1" }, "locus": { "chromosome": "1", "start_pos": 137286072, "end_pos": 137223508, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034703.1", "url": "https://www.ensembl.org/id/ENSGALT00010034703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020360.1", "url": "https://www.ensembl.org/id/ENSGALP00010020360.1" } ] } }, { "isoform_ac": "A0A8V0YNX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX8/entry", "sequence": { "sequence": "MDLEKPPSFPHILFWQFAKRKKTSLWFTVSLLVVSIFILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIVGIHLVENRRQMLVASIVFISFGVVAAFCCAIVDGVFAARHIEPRPLYNRRCQFYSSGVGFLYDAYQTEVTCYTLNTKCQLKVKSNTCYCCDLYNCENSEQSSSYYEFLGVSSCQDVVHLYRLLWSSTVLNIIGLFLGIITAAILGAFKDMVPMSHIAFSSAPPPQILYNPAQQILTYAGFCPSAATISAYPSYPLPLQPASNFPGTSSTDISLSEETQPPSQSSSSYGLPPNAPPLYAPTYFLPGEKPPPYAP", "length": 325, "header": "tr|A0A8V0YNX8-1|A0A1D5PFG6_CHICK Computationally mapped isoform of Transmembrane protein 255B OS=Gallus gallus OX=9031 GN=TMEM255B PE=3 SV=1 CANONICAL=A0A1D5PFG6-1" }, "locus": { "chromosome": "1", "start_pos": 137279956, "end_pos": 137223508, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034662.1", "url": "https://www.ensembl.org/id/ENSGALT00010034662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020341.1", "url": "https://www.ensembl.org/id/ENSGALP00010020341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418738", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418738", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK90-1", "protein_name": "Transmembrane protein 255B", "gene_name": "Tmem255b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLPPPVPGPLALLDTTEGFARRKKISLWFVGSLLLVSTLILTIGLAATTRTENVTVGGYYPGIILGFGSFLGIIGIHLVENRRQMLVAAIVFLSFGVVAAFCCAIVDGVFAARHIEPRPLSAGRCQFYSSGAGYLYDVYQTEVTCYSLSGRCQLKVRSNTCYCCDLYACGSAEPSPAYYEFVGVRSCRDVVHLYRLLWASTVLNVLGLCLGIVTAAVLGAFKDMVPLSQLAYGPSPPPQILYNPAQQILAYTGLCPPSMSVPTCSSYPLPLQPSSAPPASADLFLPEDTESPSQCHSSHGHPHAPSPCTPAYFLPGEKPPPYVP", "length": 326 }, "evidence": [ { "id": "A0A1D5PFG6", "url": "https://omabrowser.org/oma/group/A0A1D5PFG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287B0T4-1", "protein_name": "Transmembrane protein 255B", "gene_name": "TMEM255B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPLQPPAPRPLALLDTTEGFARRKKTSLWFVGSLLVVSTFILTLGLTANTRTENVAVGGYYPGIVLGFGSFLGIIGIHLVENRRQMLVAAVVFISFGVVAAFCCAIVDGVFAARHIEPRPLVAGRCQFYSSEVGYLHDVYQTEVTCHSLNGQCQLKVKGDTCYCCDLYNCQSAEHPATYYEFVGVSSCQDVLHLYRLLWASAVLNVLGLFLGIVTAAVLGAFKDMVPLSQLAYGPSSPPQTLYNPAQQILAYAGFCQAPPAGAPCSSFPLPLQPSCTFTASPRTDLSLSEDVWLPSQSSSGCRLPPNAPPVSAPTCFLPGEKPPPYAP", "length": 329 }, "evidence": [ { "id": "A0A1D5PFG6", "url": "https://omabrowser.org/oma/group/A0A1D5PFG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FW56-1", "protein_name": "Transmembrane protein 255B", "gene_name": "Tmem255b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGAEGRWREKGNDQRRGRKKRGGVEESGHRAAFLETAGTLKPNHRAGGASGHCPPSGGHFGNAAAPTARARPSGSAGHHRGLCQEEEDLSVVCGLSPAGVYSHPDHWPCCNHQDRECDCGRLLPRDYFAASIVFLSFGVVAAFCCAIVDSVFAARHIEPRPLSAGRCQFYSSGAGYLYDVYQTEVTCYSLNGRCQLKVRSNTCYCCDLYACGSTEPSPAYYEFVGVRSCQDVVHLYRLLWVSTVLNVLGLCLGIVTAAVLGAFKDMVPLSQLAYGPSPPPQILYNPAQQILAYTGLCPPSMGVPTCSSYPLPLQPSSAPPASASADLSLPEDTESPSQCQPSRGCSHAPSPCTPAYFLPGEKPPPYAP", "length": 369 }, "evidence": [ { "id": "A0A1D5PFG6", "url": "https://omabrowser.org/oma/group/A0A1D5PFG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WV15-1", "protein_name": "Transmembrane protein 255B", "gene_name": "TMEM255B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYPGIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLTTGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEFIGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTLYNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKPPPYAP", "length": 326 }, "evidence": [ { "id": "A0A1D5PFG6", "url": "https://omabrowser.org/oma/group/A0A1D5PFG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFG6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 331, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PFG6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFG6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFM9-1", "uniprot_ac": "A0A1D5PFM9", "uniprot_id": "A0A1D5PFM9_CHICK", "mass": { "chemical_mass": 20854.0, "monoisotopic_mass": 20854.0 }, "refseq": { "ac": "NP_001392769", "name": "gastrokine-2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" }, "gene_names": [ { "name": "GKN2", "type": "recommended", "evidence": [ { "id": "A0A1D5PFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" } ] }, { "name": "GDDR", "type": "synonym", "evidence": [ { "id": "NP_001392769", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" } ] }, { "name": "GKN2", "type": "synonym", "evidence": [ { "id": "NP_001392769", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" } ] } ], "protein_names": [ { "name": "Gastrokine-2", "type": "recommended", "evidence": [ { "id": "A0A1D5PFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9/entry#names_and_taxonomy" } ] }, { "name": "Blottin", "type": "synonym", "evidence": [ { "id": "A0A1D5PFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9/entry#names_and_taxonomy" } ] }, { "name": "down-regulated in gastric cancer GDDR", "type": "synonym", "evidence": [ { "id": "NP_001392769", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" } ] }, { "name": "gastrokine-2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001392769", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004170.1, BX932799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000331.1. On or before May 4, 2022 this sequence version replaced XP_417666.1, XP_040545499.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001392769", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GKN2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9", "locus": { "chromosome": "22", "start_pos": 318947, "end_pos": 314449, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019314", "url": "https://www.ensembl.org/id/ENSGALG00010019314" } ] } } ], "crossref": [ { "id": "A0A1D5PFM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039187", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039187", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419515", "url": "https://www.ncbi.nlm.nih.gov/gene/419515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419515", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YILKMNH", "url": "https://omabrowser.org/oma/group/YILKMNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFM9", "url": "https://www.orthodb.org/?gene=A0A1D5PFM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001392769", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392769", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAFAAILILLGVFWTQTSALESYLLPAPNNEYVTGSMTIDNKKNYADVHVRSGLYSSDTIFDYQHGYIATRLFSRNACFIMKIDEASIPELQEIGRQAFERQTMKKIYSPRVMWVQFQSGNAMFGSIREWLRYGRPIEQLCKGLPLYKLTKSEPLTNSNSCASAGIPSILGINICERLRENY", "length": 183, "header": "tr|A0A1D5PFM9-1|A0A1D5PFM9_CHICK Isoform 1 of Gastrokine-2 OS=Gallus gallus OX=9031 GN=GKN2 PE=4 SV=1 CANONICAL=A0A1D5PFM9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9/entry", "sequence": { "sequence": "MKAFAAILILLGVFWTQTSALESYLLPAPNNEYVTGSMTIDNKKNYADVHVRSGLYSSDTIFDYQHGYIATRLFSRNACFIMKIDEASIPELQEIGRQAFERQTMKKIYSPRVMWVQFQSGNAMFGSIREWLRYGRPIEQLCKGLPLYKLTKSEPLTNSNSCASAGIPSILGINICERLRENY", "length": 183, "header": "tr|A0A1D5PFM9-1|A0A1D5PFM9_CHICK Isoform 1 of Gastrokine-2 OS=Gallus gallus OX=9031 GN=GKN2 PE=4 SV=1 CANONICAL=A0A1D5PFM9-1" }, "locus": { "chromosome": "22", "start_pos": 318799, "end_pos": 315623, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046707.1", "url": "https://www.ensembl.org/id/ENSGALT00010046707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027815.1", "url": "https://www.ensembl.org/id/ENSGALP00010027815.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419515", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q29TV8-1", "protein_name": "Gastrokine-2", "gene_name": "Gkn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSLVAFLVVLSILRIQSQAKEVFNIFVPGNNGGNVQETVTIDNQENTATINIHSGSCSSTTIFDYKHGYIASRVLSRRACYIIKMDHKAIPALDKLQRFLYEKQTMNAMASTEYTWVKYNPLKSLITKVDWFLFGSPIEQLCKHIPLYEGEVATKPREVGTGGCAKVGILGILGISICGGIHL", "length": 184 }, "evidence": [ { "id": "A0A1D5PFM9", "url": "https://omabrowser.org/oma/group/A0A1D5PFM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86XP6-1", "protein_name": "Gastrokine-2", "gene_name": "GKN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKILVAFLVVLTIFGIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSSTTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKYNPLESLIKDVDWFLLGSPIEKLCKHIPLYKGEVVENTHNVGAGGCAKAGLLGILGISICADIHV", "length": 184 }, "evidence": [ { "id": "A0A1D5PFM9", "url": "https://omabrowser.org/oma/group/A0A1D5PFM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQS6-1", "protein_name": "Gastrokine-2", "gene_name": "Gkn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPLVAFLVVLSIFGIQSQAEEIFNIFVPSKNGGNIQETVTIDNQQNTATINIHSGSCSSTTIFDYKHGYIASRVLSRRACYVIKMDHKAIPALDKLQRFLYEKQTMNAIDSPEYTWVRYNPLKSLITKVDWFLFGSPIRQLCKHMPLYEGEVATKPKEVSTGACAKVGLLGILGVSICGGIHL", "length": 184 }, "evidence": [ { "id": "A0A1D5PFM9", "url": "https://omabrowser.org/oma/group/A0A1D5PFM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 183, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PFM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFM9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFM9" }, { "id": "PS50869", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50869" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRICHOS", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 150, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFQ6-1", "uniprot_ac": "A0A1D5PFQ6", "uniprot_id": "A0A1D5PFQ6_CHICK", "mass": { "chemical_mass": 64826.0, "monoisotopic_mass": 64826.0 }, "refseq": { "ac": "XP_015155528", "name": "transcriptional repressor p66-alpha isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155528" }, "gene_names": [ { "name": "GATAD2A", "type": "recommended", "evidence": [ { "id": "A0A1D5PFQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ] }, { "name": "GATAD2A", "type": "synonym", "evidence": [ { "id": "XP_015155528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155528" } ] } ], "protein_names": [ { "name": "GATA zinc finger domain containing 2A", "type": "synonym", "evidence": [ { "id": "A0A1D5PFQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6/entry#names_and_taxonomy" } ] }, { "name": "transcriptional repressor p66-alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GATAD2A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6", "locus": { "chromosome": "28", "start_pos": 3903059, "end_pos": 3947011, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028516", "url": "https://www.ensembl.org/id/ENSGALG00010028516" } ] } } ], "crossref": [ { "id": "A0A1D5PFQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042900", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420109", "url": "https://www.ncbi.nlm.nih.gov/gene/420109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420109", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMRVIPE", "url": "https://omabrowser.org/oma/group/DMRVIPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFQ6", "url": "https://www.orthodb.org/?gene=A0A1D5PFQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PG96", "url": "https://www.orthodb.org/?gene=A0A1D5PG96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TYJ7", "url": "https://www.orthodb.org/?gene=A0A3Q2TYJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13455:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13455:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16563", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16563", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6804758", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804758", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937850", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PG96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PG96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYJ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEEACRTRSQKRALEREVPHNDVDSKKLKMEKGLLGTEISAEGDMKIKTDPGAGKVQGLLKSGEVKATIKVEVQTGDEPVDMSTSKSEIKREKRVPSPDVIVLSDNEPSSPRMNGLTKIALKETNTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKETTAQKPACSSGSAVATPPPLVRGTQSVPAGKPSLQTSSTRIPGTVIPPPLVRGGQQTSAKLGTQQNTQIVMPPLVRGAQQIHNIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLIVNIPQASPTSIKGTTVTSAQANATTTSAASIVNSNESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGKVSIPVSSREPYMCAQCKTDFTCRWREEKNGTIMCETCMTSNQKKALKAEHTNRLKAAFVKALQQEQEIEQRILQQTASPVQSKSDPIVQHHSLKQTSSQMSRGSGAPRGVLHAFSQSPKLQNASSAAALGSRPGKHAERPVSKGSAAAWKKTPINTGGALPFVNPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK", "length": 599, "header": "tr|A0A1D5PFQ6-1|A0A1D5PFQ6_CHICK Isoform 1 of GATA zinc finger domain containing 2A OS=Gallus gallus OX=9031 GN=GATAD2A PE=1 SV=1 CANONICAL=A0A1D5PFQ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6/entry", "sequence": { "sequence": "MTEEACRTRSQKRALEREVPHNDVDSKKLKMEKGLLGTEISAEGDMKIKTDPGAGKVQGLLKSGEVKATIKVEVQTGDEPVDMSTSKSEIKREKRVPSPDVIVLSDNEPSSPRMNGLTKIALKETNTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKETTAQKPACSSGSAVATPPPLVRGTQSVPAGKPSLQTSSTRIPGTVIPPPLVRGGQQTSAKLGTQQNTQIVMPPLVRGAQQIHNIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLIVNIPQASPTSIKGTTVTSAQANATTTSAASIVNSNESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGKVSIPVSSREPYMCAQCKTDFTCRWREEKNGTIMCETCMTSNQKKALKAEHTNRLKAAFVKALQQEQEIEQRILQQTASPVQSKSDPIVQHHSLKQTSSQMSRGSGAPRGVLHAFSQSPKLQNASSAAALGSRPGKHAERPVSKGSAAAWKKTPINTGGALPFVNPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK", "length": 599, "header": "tr|A0A1D5PFQ6-1|A0A1D5PFQ6_CHICK Isoform 1 of GATA zinc finger domain containing 2A OS=Gallus gallus OX=9031 GN=GATAD2A PE=1 SV=1 CANONICAL=A0A1D5PFQ6-1" }, "locus": { "chromosome": "28", "start_pos": 3923084, "end_pos": 3906077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069065.1", "url": "https://www.ensembl.org/id/ENSGALT00010069065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042507.1", "url": "https://www.ensembl.org/id/ENSGALP00010042507.1" } ] } }, { "isoform_ac": "A0A1D5PG96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG96/entry", "sequence": { "sequence": "MTEEACRTRSQKRALEREVPHNDVDSKKLKMEKGLLGTEISAEGDMKIKTDPGAGKVQGLLKSGEVKATIKVEVQTGDEPVDMSTSKSEIKREKRVPSPDVIVLSDNEPSSPRMNGLTKIALKETNTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKETTAQKTSSTRIPGTVIPPPLVRGGQQTSAKLGTQQNTQIVMPPLVRGAQQIHNIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLIVNIPQASPTSIKGTTVTSAQANATTTSAASIVNSNESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGKVSIPVSSREPYMCAQCKTDFTCRWREEKNGTIMCETCMTSNQKKALKAEHTNRLKAAFVKALQQEQEIEQRILQQTASPVQSKSDPIVQHHSLKQTSSQMSRGSGAPRGVLHAFSQSPKLQNASSAAALGSRPGKHAERPVSKGSAAAWKKTPINTGGALPFVNPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK", "length": 569, "header": "tr|A0A1D5PG96-1|A0A1D5PG96_CHICK Computationally mapped isoform of GATA zinc finger domain containing 2A OS=Gallus gallus OX=9031 GN=GATAD2A PE=1 SV=1 CANONICAL=A0A1D5PFQ6-1" }, "locus": { "chromosome": "28", "start_pos": 3923084, "end_pos": 3906077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069066.1", "url": "https://www.ensembl.org/id/ENSGALT00010069066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042508.1", "url": "https://www.ensembl.org/id/ENSGALP00010042508.1" } ] } }, { "isoform_ac": "A0A3Q2TYJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ7/entry", "sequence": { "sequence": "MTEEACRTRSQKRALEREVPHNDVDSKKLKMEKGLLGTEISAEGDMKIKTDPGAGKVQGLLKSGEVKATIKVEVQTGDEPVDMSTSKSEIKREKRVPSPDVIVLSDNEPSSPRMNGLTKIALKETNTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKETTAQKQIHNIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLIVNIPQASPTSIKGTTVTSAQANATTTSAASIVNSNESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGKVSIPVSSREPYMCAQCKTDFTCRWREEKNGTIMCETCMTSNQKKALKAEHTNRLKAAFVKALQQEQEIEQRILQQTASPVQSKSDPIVQHHSLKQTSSQMSRGSGAPRGVLHAFSQSPKLQNASSAAALGSRPGKHAERPVSKGSAAAWKKTPINTGGALPFVNPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK", "length": 525, "header": "tr|A0A3Q2TYJ7-1|A0A3Q2TYJ7_CHICK Computationally mapped isoform of GATA zinc finger domain containing 2A OS=Gallus gallus OX=9031 GN=GATAD2A PE=1 SV=1 CANONICAL=A0A1D5PFQ6-1" }, "locus": { "chromosome": "28", "start_pos": 3923084, "end_pos": 3906077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069069.1", "url": "https://www.ensembl.org/id/ENSGALT00010069069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042511.1", "url": "https://www.ensembl.org/id/ENSGALP00010042511.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420109", "resource": "KEGG Pathway" }, { "id": "R-GGA-6804758", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804758", "resource": "Reactome", "description": "Regulation of TP53 Activity through Acetylation" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IN87-1", "protein_name": "GATA zinc finger domain containing 2Ab isoform X1", "gene_name": "gatad2ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSGSTCAVPGCHNNSKKLKSFQENICIEHQKSRNECPCAAPYALHCMPTKAERKRAWLSALKLKNPPKRVYVCSFHFVDKKPTELHPDPELYLGQDRPQQSKRKQTEETGGLGEKMSEDAGRQTRSQKRALERDVPTPETDVKRVKLERGEPGAVDGLKTKSEQANKVANILRAGEVKATIKVEVQTSDEPVDMSTSKSDIKKERPSTPDDDVIVLSDNEPSSPCMNGVSYTFKKTDTDMLMKSSPAERTHIIKQLQEELRLQEAKLVLLKKLRQSQIQKDAVQKSSNSVAAPPPLVRGSISSTKGPLQVSNRNSGTVIPPPLVRGGAQVSKHSTHNTVVMPPLVRGSQPIAVTPQQIATLRQQQQQQHSGSGPPPLLLGTRTSVPTVQVQGQRIIQQGLIRVASVGNANVLVSQASSTGLKTSQSGLGSSSSNANDSPASRQAAAKLALRKQLEKTLLEIPPPKPPAPELNFLPSAANNEFIYLVGLEMVVQNLLDTLAKSKHQQSDSASNTAPKEPFTCAQCQTDFTSRWRQEKNNGSILCEHCMSSNQKKVLKAEHTSRLKAAFVKALQQEQEIEQRILQQAASPKTTTTSSSSSSSSPVIKAEHVLVSPQYKQVRASLPQQTNRGHYHTTTIKQTPGQLSRTVQQVVNAGARVSHSFSTSSQLQNAATAAALVSRPGKHAVRAGEKGTSSSKATTNTWRKQNSGTTGVTMAYVNPSLSVHRTTSPVDRQREYLLDMIPSRSISQTANTWK", "length": 755 }, "evidence": [ { "id": "A0A1D5PFQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PFQ6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86YP4-1", "protein_name": "Transcriptional repressor p66-alpha", "gene_name": "GATAD2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMRVTPEPGAGPTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQVIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK", "length": 633 }, "evidence": [ { "id": "A0A1D5PFQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PFQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFQ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 599, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PFQ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFQ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 522, "end_pos": 524 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFS5-1", "uniprot_ac": "A0A1D5PFS5", "uniprot_id": "A0A1D5PFS5_CHICK", "mass": { "chemical_mass": 14966.0, "monoisotopic_mass": 14966.0 }, "refseq": { "ac": "NP_001376407", "name": "maturin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" }, "gene_names": [ { "name": "MTURN", "type": "recommended", "evidence": [ { "id": "A0A1D5PFS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5" } ] }, { "name": "C2H7ORF41", "type": "synonym", "evidence": [ { "id": "NP_001376407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" } ] }, { "name": "C7orf41", "type": "synonym", "evidence": [ { "id": "NP_001376407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" } ] }, { "name": "MTURN", "type": "synonym", "evidence": [ { "id": "NP_001376407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" } ] } ], "protein_names": [ { "name": "Maturin", "type": "recommended", "evidence": [ { "id": "A0A1D5PFS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5/entry#names_and_taxonomy" } ] }, { "name": "maturin", "type": "synonym", "evidence": [ { "id": "NP_001376407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01020913.1, HAEK01058909.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08016669 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000037.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTURN", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5", "locus": { "chromosome": "2", "start_pos": 41238490, "end_pos": 41284980, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016876", "url": "https://www.ensembl.org/id/ENSGALG00010016876" } ] } } ], "crossref": [ { "id": "A0A1D5PFS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029724", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029724", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420679", "url": "https://www.ncbi.nlm.nih.gov/gene/420679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YEQYHAD", "url": "https://omabrowser.org/oma/group/YEQYHAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFS5", "url": "https://www.orthodb.org/?gene=A0A1D5PFS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32008", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32008", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32008:SF2", "url": 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"MAFEALAEAAERWCARTPFQLIAAEETERRMDFYAEPGVSFYVLCPEAACGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEILEKVFKSFRPLLGLPDVDDDAFEEYNADMEEEEPEADHQQMGVSQQ", "length": 131, "header": "tr|A0A1D5PFS5-1|A0A1D5PFS5_CHICK Isoform 1 of Maturin OS=Gallus gallus OX=9031 GN=MTURN PE=1 SV=2 CANONICAL=A0A1D5PFS5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5/entry", "sequence": { "sequence": "MAFEALAEAAERWCARTPFQLIAAEETERRMDFYAEPGVSFYVLCPEAACGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEILEKVFKSFRPLLGLPDVDDDAFEEYNADMEEEEPEADHQQMGVSQQ", "length": 131, "header": "tr|A0A1D5PFS5-1|A0A1D5PFS5_CHICK Isoform 1 of Maturin OS=Gallus gallus OX=9031 GN=MTURN PE=1 SV=2 CANONICAL=A0A1D5PFS5-1" }, "locus": { "chromosome": "2", "start_pos": 41284925, "end_pos": 41275415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040708.1", "url": "https://www.ensembl.org/id/ENSGALT00010040708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023674.1", "url": "https://www.ensembl.org/id/ENSGALP00010023674.1" } ] } }, { "isoform_ac": "A0A8V0Z572-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z572/entry", "sequence": { "sequence": "MAFEALAEAAERWCARTPFQLIAAEETERRMDFYAEPGVSFYVLCPEAACGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEILEKVFKSFRPLLGLPDVDDDAFEEYNADMEEEEPEADHQQMGVFASEISLLAGM", "length": 139, "header": "tr|A0A8V0Z572-1|A0A8V0Z572_CHICK Computationally mapped isoform of Maturin OS=Gallus gallus OX=9031 GN=MTURN PE=1 SV=1 CANONICAL=A0A1D5PFS5-1" }, "locus": { "chromosome": "2", "start_pos": 41284925, "end_pos": 41241852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040713.1", "url": "https://www.ensembl.org/id/ENSGALT00010040713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023677.1", "url": "https://www.ensembl.org/id/ENSGALP00010023677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P0C8M4-1", "protein_name": "Maturin", "gene_name": "mturn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFKELVDAAEKWCTGNPFDLIFAEDVDERRLDFYAEPGISFYVLCPDNLTGGTDNFHVWSESEDCLPFLQLAQDYISSCGKKTLLEVLDKVFRSFRPLLGLPDIDDDTFDQYHADVEEEPEPDHQQMGVSQQ", "length": 133 }, "evidence": [ { "id": "A0A1D5PFS5", "url": "https://omabrowser.org/oma/group/A0A1D5PFS5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5XI20-1", "protein_name": "Maturin", "gene_name": "Mturn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFQQLADVAEKWCSSTPFELIAAEETERRMDFYADPGVSFYVLCPDNGCGDSFHVWSESEDCLPFLQLAQDYISSCGKKTLQEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ", "length": 131 }, "evidence": [ { "id": "A0A1D5PFS5", "url": "https://omabrowser.org/oma/group/A0A1D5PFS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CGA4-1", "protein_name": "Maturin", "gene_name": "Mturn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFQQLADVAEKWCSSTPFELIAAEETERRMDFYADPGVSFYVLCPDNGCGDSFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ", "length": 131 }, "evidence": [ { "id": "A0A1D5PFS5", "url": "https://omabrowser.org/oma/group/A0A1D5PFS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3F0-1", "protein_name": "Maturin", "gene_name": "MTURN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ", "length": 131 }, "evidence": [ { "id": "A0A1D5PFS5", "url": "https://omabrowser.org/oma/group/A0A1D5PFS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, 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"database": "UniProtKB", "id": "A0A1D5PFS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5" } ], "pmid": "" }, { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFT6-1", "uniprot_ac": "A0A1D5PFT6", "uniprot_id": "A0A1D5PFT6_CHICK", "mass": { "chemical_mass": 33275.0, "monoisotopic_mass": 33275.0 }, "refseq": { "ac": "XP_004941749", "name": "sushi domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941749" }, "gene_names": [ { "name": "SUSD6", "type": "recommended", "evidence": [ { "id": "A0A1D5PFT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6" } ] }, { "name": "SUSD6", "type": "synonym", "evidence": [ { "id": "XP_004941749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941749" } ] } ], "protein_names": [ { "name": "Sushi domain containing 6", "type": "synonym", "evidence": [ { "id": "A0A1D5PFT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6/entry#names_and_taxonomy" } ] }, { "name": "sushi domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004941749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFT6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUSD6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6", "locus": { "chromosome": "5", "start_pos": 27402503, "end_pos": 27476020, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021535", "url": "https://www.ensembl.org/id/ENSGALG00010021535" } ] } } ], "crossref": [ { "id": "A0A1D5PFT6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFT6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009428", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423259", "url": "https://www.ncbi.nlm.nih.gov/gene/423259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423259", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHASGCQ", "url": "https://omabrowser.org/oma/group/GHASGCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFT6", "url": "https://www.orthodb.org/?gene=A0A1D5PFT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD33", "url": "https://www.orthodb.org/?gene=A0A8V0ZD33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKB6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46839", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46839", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46839:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46839:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFT6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHGMVAPKSNTGSSLALTSHGLFLLLVIFGNFILEAQATGWLSKSKGPAYCPQPPQPENGGYKCHPSPCNDPLTSGSVIEYLCVEGYMLKGDYKYLTCKNGEWNPAMEVSCRLSPEKDSPPTIGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSTGNCIPPSDSRVQIVLSEGAGQNGTREMQQQDQGVRSNLDREDEAPGHSGLCEASGSQRSETVLVHQAATSSWVAGMASSRPIQKEVQDSESSDIQSLLSLTSSEEYTDDIPLLKEA", "length": 311, "header": "tr|A0A1D5PFT6-1|A0A1D5PFT6_CHICK Isoform 1 of Sushi domain containing 6 OS=Gallus gallus OX=9031 GN=SUSD6 PE=4 SV=2 CANONICAL=A0A1D5PFT6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6/entry", "sequence": { "sequence": "MCHGMVAPKSNTGSSLALTSHGLFLLLVIFGNFILEAQATGWLSKSKGPAYCPQPPQPENGGYKCHPSPCNDPLTSGSVIEYLCVEGYMLKGDYKYLTCKNGEWNPAMEVSCRLSPEKDSPPTIGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSTGNCIPPSDSRVQIVLSEGAGQNGTREMQQQDQGVRSNLDREDEAPGHSGLCEASGSQRSETVLVHQAATSSWVAGMASSRPIQKEVQDSESSDIQSLLSLTSSEEYTDDIPLLKEA", "length": 311, "header": "tr|A0A1D5PFT6-1|A0A1D5PFT6_CHICK Isoform 1 of Sushi domain containing 6 OS=Gallus gallus OX=9031 GN=SUSD6 PE=4 SV=2 CANONICAL=A0A1D5PFT6-1" }, "locus": { "chromosome": "5", "start_pos": 27445253, "end_pos": 27406038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052234.1", "url": "https://www.ensembl.org/id/ENSGALT00010052234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031202.1", "url": "https://www.ensembl.org/id/ENSGALP00010031202.1" } ] } }, { "isoform_ac": "A0A8V0ZD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD33/entry", "sequence": { "sequence": "MLKRFPLSYPSLGSILKALFVYCPQPPQPENGGYKCHPSPCNDPLTSGSVIEYLCVEGYMLKGDYKYLTCKNGEWNPAMEVSCRLSPEKDSPPTIGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSTGNCIPPSDSRVQIVLSEGAGQNGTREMQQQDQGVRSNLDREDEAPGHSGLCEASGSQRSETVLVHQAATSSWVAGMASSRPIQKEVQDSESSDIQSLLSLTSSEEYTDDIPLLKEA", "length": 282, "header": "tr|A0A8V0ZD33-1|A0A8V0ZD33_CHICK Computationally mapped isoform of Sushi domain containing 6 OS=Gallus gallus OX=9031 GN=SUSD6 PE=4 SV=1 CANONICAL=A0A1D5PFT6-1" }, "locus": { "chromosome": "5", "start_pos": 27428075, "end_pos": 27406038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052227.1", "url": "https://www.ensembl.org/id/ENSGALT00010052227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031198.1", "url": "https://www.ensembl.org/id/ENSGALP00010031198.1" } ] } }, { "isoform_ac": "A0A8V0ZKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKB6/entry", "sequence": { "sequence": "MCHGMVAPKSNTGSSLALTSHGLFLLLVIFGNFILEAQATGWLSKSKGPAYCPQPPQPENGGYKCHPSPCNDPLTSGSVIEYLCVEGYMLKGDYKYLTCKNGEWNPAMEVSCRLSPEKDSPPTIGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSTGNCIPPSDSRVQIVLSEGAGQNGTREMQQQDQGVRSNLDREDEAPGHSGLCEASGSQRSETVLVHQAATSSWVAGMASSRPIQKEVQDSESSDIQSLLSLTSSEEYTDGM", "length": 305, "header": "tr|A0A8V0ZKB6-1|A0A8V0ZKB6_CHICK Computationally mapped isoform of Sushi domain containing 6 OS=Gallus gallus OX=9031 GN=SUSD6 PE=4 SV=1 CANONICAL=A0A1D5PFT6-1" }, "locus": { "chromosome": "5", "start_pos": 27445253, "end_pos": 27407512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052232.1", "url": "https://www.ensembl.org/id/ENSGALT00010052232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031201.1", "url": "https://www.ensembl.org/id/ENSGALP00010031201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423259", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK85-1", "protein_name": "Sushi domain containing 6", "gene_name": "Susd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCHGRIAPKSSSEFVVTSVGHGVFLQLVILCSLLGDGLASVCPLPPEPENGGYICHPRPCKDPLTSGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEVSCHLNEDKETHASLGVPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRREQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCMPPADPRVQIVLSEGSAPSGRNMPREQQLQGQAACSSAGGEDEAPGHSGLCEAWGSQGSETVMVHQATTSSWVAGSGSSRQTHKDTADSENSDIQSLLSLTSEEYTDDIPLLKEA", "length": 303 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAF6DMF3-1", "protein_name": "Sushi domain containing 6", "gene_name": "SUSD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCHGRIAPKSTSAFAVASVGHGVFLPLVILSTLLGDGLASVCSLPPEPENGGYICHPRPCRDPLNSGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDIHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSGMREPHPQDQGACSSAGSEEEAPGQSGLCEAWGSRGSETVMVHQATTSSWVAGSGNSRAAHKEAPDSENSDIQSLASEDYTDGNSGAFVVKPSEDEIAPS", "length": 310 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S4B3-1", "protein_name": "Sushi domain containing 6", "gene_name": "SUSD6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCHGRIAPKSTSAFASASVGHGVFLRLVILSTLLGDGLASVCSLPPEPENGGYVCHPRPCRDPLNAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDAHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHSVPPADPRVQIVLSEGSGPGGRSGPREQQLQDQGACSSAGGEEEAPGQSGLCEAWGSRGSETVMVHQATTSSWVAGSGNSRVAHKEAPDSENSDMQSLLSLTSEDYTDDIPLLKEA", "length": 303 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H1N9-1", "protein_name": "Sushi domain-containing protein 6", "gene_name": "Susd6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCHGRIAPKSNSAFVVTSVGHGVFLQLVILSTLLGDGLTSVCPLPPEPENGGYICHPRPCKDPLTAGSVIEYLCAEGYMLKGDYKYLTCKDGEWKPAMEVSCHLNEDKETHTSLGVPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHNRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCMPPADPRVQIVLSEGSAPSGRNVPREQQLQGQGACSSAGGEDEAPGHSGLCEAWGSQGSETVMVHQATTSSWVAGSGSSRPTHKDAADSENSDIQSLLSLTSEEYTDDIPLLKEA", "length": 303 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BGE4-1", "protein_name": "Sushi domain-containing protein 6", "gene_name": "Susd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCHGKIAPKSSSEFVVTSVGHGVFLQLVILCALLGDGLASVCPLPPEPENGGYICHPRPCKDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWTPAMEVSCHLIEDKETHALGVPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRREQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCMPPADPRVQIVLSEGSAPSGRNMPREQQLQGQEACSSAGGEDEAPGHSGLCEAWGSQGSETVMVHQATTSSWVAGSGSSRPTHKDTADSENSDIQSLLSLTSEEYTDDIPLLKEA", "length": 302 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92537-1", "protein_name": "Sushi domain-containing protein 6", "gene_name": "SUSD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLLKEA", "length": 303 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "U3JAN2-1", "protein_name": "Sushi domain-containing protein 6 precursor", "gene_name": "susd6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCNGMVACETRASLAHGVASTSLLLLLAMLPTGQASGCPRPTVVPHGRGNLTEMNRGSFSVGTLLQYSCDPGYTLDGVSMISCTVTGQWSSNPPRCIKNDGMYDVCQPPSEPENGGYNCHPSPCHRLTQGTVIEYFCDEGYILKGGYQFRTCESGEWNSPMQISCHPVQGEEQHSSLPMPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRSREQGVSGQHSSMMVGGVQVSLPSYEEAVYGAGGTSVPPPESRVQIVLSEGPQAEALHEPLEQAQASYSFPSTSAAASSCHAETVLVHQVACSSSPSSSSSPSWAVEQPGAAAPLHRQQSSESSDQHSLLSVTSAEDYGDDIPLLKEA", "length": 364 }, "evidence": [ { "id": "A0A1D5PFT6", "url": "https://omabrowser.org/oma/group/A0A1D5PFT6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFT6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PFT6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PFT6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PFT6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PFX6-1", "uniprot_ac": "A0A1D5PFX6", "uniprot_id": "A0A1D5PFX6_CHICK", "mass": { "chemical_mass": 93044.0, "monoisotopic_mass": 93044.0 }, "refseq": { "ac": "NP_996869", "name": "RNA-binding protein 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869" }, "gene_names": [ { "name": "RBM12", "type": "recommended", "evidence": [ { "id": "A0A1D5PFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ] }, { "name": "RBM12", "type": "synonym", "evidence": [ { "id": "NP_996869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869" } ] } ], "protein_names": [ { "name": "RNA-binding protein 12", "type": "recommended", "evidence": [ { "id": "A0A1D5PFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 12", "type": "synonym", "evidence": [ { "id": "A0A1D5PFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 12", "type": "synonym", "evidence": [ { "id": "NP_996869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869" } ] }, { "name": "SWAN ribonucleoprotein", "type": "synonym", "evidence": [ { "id": "NP_996869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY239220.1, SRR13267658.8018.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On Feb 27, 2015 this sequence version replaced NP_996869.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_996869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM12", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6", "locus": { "chromosome": "20", "start_pos": 1413017, "end_pos": 1388407, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024095", "url": "https://www.ensembl.org/id/ENSGALG00010024095" } ] } } ], "crossref": [ { "id": "ENSGALG00000030253", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12512", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12512", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12749", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12749", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12751", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12751", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "404531", "url": "https://www.ncbi.nlm.nih.gov/gene/404531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:404531", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IIMNAEA", "url": "https://omabrowser.org/oma/group/IIMNAEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFX6", "url": "https://www.orthodb.org/?gene=A0A1D5PFX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_996869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDMPPANASRSGPPPSSGMSGRVNLPTTVPNFNNPSPSVVTASTTVHESNKNISTFSTASMGTAPPNLGSTFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPPVPPMTPIPPISGMPPLNPPPVAPLPTGMNGSGAAVNMNSGLNPLFIGPMNPVNPIQMNSQSSVKPIPINPDDLYVSIHGMPFSATESDVKEFFLGLRVDAIHMLKDHVGRNNGNGLVKFFSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQTMGPSGQPHPPPPQPHSRSKSPSGQKRSRSRSPHEQGFCVYLKGLPFESENKHVIDFFKKLDIVEDSIYIAYGPNGKAIGEGFVEFRNEADYKAALCHHKQYIGNRFIQVHPITKKAMLEKIDLIRKRLQNFNYDQREIIMNAEAESGSPKLCAHISNIPYNITKMEILQFLEGLAVEENSVQILVDNNGQGLGQALVQFKAEDDARKAERLHRKKLNGRDVVLRLITVEEMRDIERNPPSQGKKILKIPIQGNAAVPGAQPPAGDEHAFLGGNPKDANNGPPFNFPGNFSGSGTFGPPLPPPGIGGFPDARPGIPAVASAGLPGAGIEVPGFAGGPANLSGPSGFGGGPQSFGNGPGNLSGPPGFAGGPPGIAGSLGHLGGPPAFGPGPGNIHISGPPGFGTGSGKPGPTVIKVQNMPFTVSVDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEAMAAVVDLNDRPIGSRKVKLVLG", "length": 880, "header": "tr|A0A1D5PFX6-1|A0A1D5PFX6_CHICK Isoform 1 of RNA-binding protein 12 OS=Gallus gallus OX=9031 GN=RBM12 PE=1 SV=1 CANONICAL=A0A1D5PFX6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6/entry", "sequence": { "sequence": "MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDMPPANASRSGPPPSSGMSGRVNLPTTVPNFNNPSPSVVTASTTVHESNKNISTFSTASMGTAPPNLGSTFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPPVPPMTPIPPISGMPPLNPPPVAPLPTGMNGSGAAVNMNSGLNPLFIGPMNPVNPIQMNSQSSVKPIPINPDDLYVSIHGMPFSATESDVKEFFLGLRVDAIHMLKDHVGRNNGNGLVKFFSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQTMGPSGQPHPPPPQPHSRSKSPSGQKRSRSRSPHEQGFCVYLKGLPFESENKHVIDFFKKLDIVEDSIYIAYGPNGKAIGEGFVEFRNEADYKAALCHHKQYIGNRFIQVHPITKKAMLEKIDLIRKRLQNFNYDQREIIMNAEAESGSPKLCAHISNIPYNITKMEILQFLEGLAVEENSVQILVDNNGQGLGQALVQFKAEDDARKAERLHRKKLNGRDVVLRLITVEEMRDIERNPPSQGKKILKIPIQGNAAVPGAQPPAGDEHAFLGGNPKDANNGPPFNFPGNFSGSGTFGPPLPPPGIGGFPDARPGIPAVASAGLPGAGIEVPGFAGGPANLSGPSGFGGGPQSFGNGPGNLSGPPGFAGGPPGIAGSLGHLGGPPAFGPGPGNIHISGPPGFGTGSGKPGPTVIKVQNMPFTVSVDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEAMAAVVDLNDRPIGSRKVKLVLG", "length": 880, "header": "tr|A0A1D5PFX6-1|A0A1D5PFX6_CHICK Isoform 1 of RNA-binding protein 12 OS=Gallus gallus OX=9031 GN=RBM12 PE=1 SV=1 CANONICAL=A0A1D5PFX6-1" }, "locus": { "chromosome": "20", "start_pos": 1398112, "end_pos": 1395473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058754.1", "url": "https://www.ensembl.org/id/ENSGALT00010058754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035722.1", "url": "https://www.ensembl.org/id/ENSGALP00010035722.1" } ] } }, { "isoform_ac": "A0A8V0ZZI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZI6/entry", "sequence": { "sequence": "MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDMPPANASRSGPPPSSGMSGRVNLPTTVPNFNNPSPSVVTASTTVHESNKNISTFSTASMGTAPPNLGSTFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPPVPPMTPIPPISGMPPLNPPPVAPLPTGMNGSGAAVNMNSGLNPLFIGPMNPVNPIQMNSQSSVKPIPINPDDLYVSIHGMPFSATESDVKEFFLGLRVDAIHMLKDHVGRNNGNGLVKFFSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQTMGPSGQPHPPPPQPHSRSKSPSGQKRSRSRSPHEQGFCVYLKGLPFESENKHVIDFFKKLDIVEDSIYIAYGPNGKAIGEGFVEFRNEADYKAALCHHKQYIGNRFIQVHPITKKAMLEKIDLIRKRLQNFNYDQREIIMNAEAESGSPKLCAHISNIPYNITKMEILQFLEGLAVEENSVQILVDNNGQGLGQALVQFKAEDDARKAERLHRKKLNGRDVVLRLITVEEMRDIERNPPSQGKKILKIPIQGNAAVPGAQPPAGDEHAFLGGNPKDANNGPPFNFPGNFSGSGTFGPPLPPPGIGGFPDARPGIPAVASAGLPGAGIEVPGFAGGPANLSGPSGFGGGPQSFGIAGSLGHLGGPPAFGPGPGNIHISGPPGFGTGSGKPGPTVIKVQNMPFTVSVDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEAMAAVVDLNDRPIGSRKVKLVLG", "length": 862, "header": "tr|A0A8V0ZZI6-1|A0A1D5PFX6_CHICK Computationally mapped isoform of RNA-binding protein 12 OS=Gallus gallus OX=9031 GN=RBM12 PE=1 SV=1 CANONICAL=A0A1D5PFX6-1" }, "locus": { "chromosome": "20", "start_pos": 1398112, "end_pos": 1395473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058742.1", "url": "https://www.ensembl.org/id/ENSGALT00010058742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035712.1", "url": "https://www.ensembl.org/id/ENSGALP00010035712.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:404531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404531", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R4X3-1", "protein_name": "RNA-binding protein 12", "gene_name": "Rbm12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLPAIVPNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPSMGTSFGSPTFSSTIPSTASPMNTVPPPPIPPIPAMPSLPPLPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTTLPPMSGMPPLNPPPVAPLPAGMNGSGAPIGLNNNMNPVFLGPLNPVNSIQMNSQSSVKSLPINPDDLYVSVHGMPFSAMENDVREFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQSMGPSGQAHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNDADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQRELVLNPEGEVSSAKVCAHITNIPFSITKMDVLQFLEGIPVDESAVHVLVDNNGQGLGQALVQFKTEDDAHKSEHLHRKKLNGREAFVHIVTLEDMREIEKNPPAQGKKGLKISVPGNPAVPVIPSAGMPAAGIPTAGIPGAGLPSAGMPGAGMPSSGMPGPGMPGPGIPGAGIPGPAMPGPAMPGPAMPGPAMPGPAMPGPAMPGPAMPGPAMPGPAIPGPAIPGPAIPGAGIPSAGGEEHVFLTVGSKEANNGPPFNFPGNFGGPNAFGPPLPPPGLGGAFGDVRPVMPSVGNSGLPGLGLEVPGFGGAPNNISGPSGFGGIPQNFGNGPGSLNAPPGFGSGPPGLGSVPGHLSGPPAFGPGPGPGPIHIGGPPGFGASSGKPGPTIIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDLNDRPIGSRKVKLVLG", "length": 992 }, "evidence": [ { "id": "A0A1D5PFX6", "url": "https://omabrowser.org/oma/group/A0A1D5PFX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PFX6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFX6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 304, "end_pos": 379, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 804 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 682, "end_pos": 684 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 752, "end_pos": 754 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PG80-1", "uniprot_ac": "A0A1D5PG80", "uniprot_id": "A0A1D5PG80_CHICK", "mass": { "chemical_mass": 29641.0, "monoisotopic_mass": 29641.0 }, "refseq": { "ac": "XP_426957", "name": "homeobox protein Hox-C12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426957" }, "gene_names": [ { "name": "HOXC12", "type": "recommended", "evidence": [ { "id": "A0A1D5PG80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ] }, { "name": "HOXC12", "type": "synonym", "evidence": [ { "id": "XP_426957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426957" } ] } ], "protein_names": [ { "name": "Homeobox C12", "type": "synonym", "evidence": [ { "id": "A0A1D5PG80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-C12", "type": "synonym", "evidence": [ { "id": "XP_426957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426957" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_426957.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426957" } ] }, { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXC12", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80", "locus": { "chromosome": "34", "start_pos": 894619, "end_pos": 896519, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025552", "url": "https://www.ensembl.org/id/ENSGALG00010025552" } ] } } ], "crossref": [ { "id": "A0A1D5PG80", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PG80", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429400", "url": "https://www.ncbi.nlm.nih.gov/gene/429400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429400", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DESKCFY", "url": "https://omabrowser.org/oma/group/DESKCFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PG80", "url": "https://www.orthodb.org/?gene=A0A1D5PG80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46440:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46440:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426957", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PG80-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRTSGGQLPGLPSLSYPRRDNVCSLPWASSEPCNGYPQPYLGSPVSINPSFGRACDLARVEESKCYYRESCSDTAGLKREERGRDSALLPLESGLPNGMGGNFSKYDYPGAEAVPHDPPSCQSLESDSSSSLLNEGNKGTAGEAGGLVSPLNQGSTLGTGGAPWYPMHTRSRKKRKPYSKLQLAELEGEFMVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF", "length": 267, "header": "tr|A0A1D5PG80-1|A0A1D5PG80_CHICK Isoform 1 of Homeobox C12 OS=Gallus gallus OX=9031 GN=HOXC12 PE=3 SV=2 CANONICAL=A0A1D5PG80-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PG80-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80/entry", "sequence": { "sequence": "MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRTSGGQLPGLPSLSYPRRDNVCSLPWASSEPCNGYPQPYLGSPVSINPSFGRACDLARVEESKCYYRESCSDTAGLKREERGRDSALLPLESGLPNGMGGNFSKYDYPGAEAVPHDPPSCQSLESDSSSSLLNEGNKGTAGEAGGLVSPLNQGSTLGTGGAPWYPMHTRSRKKRKPYSKLQLAELEGEFMVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF", "length": 267, "header": "tr|A0A1D5PG80-1|A0A1D5PG80_CHICK Isoform 1 of Homeobox C12 OS=Gallus gallus OX=9031 GN=HOXC12 PE=3 SV=2 CANONICAL=A0A1D5PG80-1" }, "locus": { "chromosome": "34", "start_pos": 896468, "end_pos": 894787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062330.1", "url": "https://www.ensembl.org/id/ENSGALT00010062330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038529.1", "url": "https://www.ensembl.org/id/ENSGALP00010038529.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429400", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PG80", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PG80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 267, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PG80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PG80" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PG80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PG80" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 199, "end_pos": 258, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PH29-1", "uniprot_ac": "A0A1D5PH29", "uniprot_id": "A0A1D5PH29_CHICK", "mass": { "chemical_mass": 48877.0, "monoisotopic_mass": 48877.0 }, "refseq": { "ac": "NP_001006480", "name": "zinc finger protein 410", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006480" }, "gene_names": [ { "name": "ZNF410", "type": "recommended", "evidence": [ { "id": "A0A1D5PH29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ] }, { "name": "ZNF410", "type": "synonym", "evidence": [ { "id": "NP_001006480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006480" } ] } ], "protein_names": [ { "name": "Zinc finger protein 410", "type": "recommended", "evidence": [ { "id": "A0A1D5PH29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 410", "type": "synonym", "evidence": [ { "id": "NP_001006480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006480" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01026480.1, HAEL01000754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On or before Dec 17, 2020 this sequence version replaced XP_015142871.1, NP_001006480.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006480" } ] }, { "annotation": "Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells. Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells. May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose. However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29#function" }, { "database": "UniProtKB", "id": "ARBA00055956", "url": "https://www.uniprot.org/uniprotkb/ARBA00055956#function" }, { "database": "UniProtKB", "id": "A0A8V0XQT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF410", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29", "locus": { "chromosome": "5", "start_pos": 37198121, "end_pos": 37179709, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006521", "url": "https://www.ensembl.org/id/ENSGALG00010006521" } ] } } ], "crossref": [ { "id": "A0A1D5PH29", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH29", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010193", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010193", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423340", "url": "https://www.ncbi.nlm.nih.gov/gene/423340", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423340", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423340", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XNDRSFI", "url": "https://omabrowser.org/oma/group/XNDRSFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PH29", "url": "https://www.orthodb.org/?gene=A0A1D5PH29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQT6", "url": "https://www.orthodb.org/?gene=A0A8V0XQT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006480", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PH29-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSDELESKPELLVQFVQNTSIPLAQGLVESEPKDITCLSLLPVTETSECNRLMLPDDERDLTSPSHANSSKDVSSSAVLRSLQVNVGPDGEETRAQNVQKPSELLSSPETSSLLQDLQPSDSTSFILLNLTRAGLGSPAEHLVFVQDEVEDSGNDFLSHDSTDSSTPWFLRVQELAHDSLIAATRAQLAKNAKASNNGENVHLCSGDGQPKDSSPIPHLSRVERKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFTCPAEGCGKSFYVLQRLKVHMRTHNGEKPFVCTELGCGKQFTTAGNLKNHLRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGVKPHQCQICGKTFSQSGSRNVHMRKHHSRIGTGGSREQEQPESLMGSSLLEESTVHSKNLISVNSQPSLGVESLHLPDTESIIGVEEGETSCSFFRPLICSD", "length": 445, "header": "tr|A0A1D5PH29-1|A0A1D5PH29_CHICK Isoform 1 of Zinc finger protein 410 OS=Gallus gallus OX=9031 GN=ZNF410 PE=4 SV=2 CANONICAL=A0A1D5PH29-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PH29-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29/entry", "sequence": { "sequence": "MLSDELESKPELLVQFVQNTSIPLAQGLVESEPKDITCLSLLPVTETSECNRLMLPDDERDLTSPSHANSSKDVSSSAVLRSLQVNVGPDGEETRAQNVQKPSELLSSPETSSLLQDLQPSDSTSFILLNLTRAGLGSPAEHLVFVQDEVEDSGNDFLSHDSTDSSTPWFLRVQELAHDSLIAATRAQLAKNAKASNNGENVHLCSGDGQPKDSSPIPHLSRVERKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFTCPAEGCGKSFYVLQRLKVHMRTHNGEKPFVCTELGCGKQFTTAGNLKNHLRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGVKPHQCQICGKTFSQSGSRNVHMRKHHSRIGTGGSREQEQPESLMGSSLLEESTVHSKNLISVNSQPSLGVESLHLPDTESIIGVEEGETSCSFFRPLICSD", "length": 445, "header": "tr|A0A1D5PH29-1|A0A1D5PH29_CHICK Isoform 1 of Zinc finger protein 410 OS=Gallus gallus OX=9031 GN=ZNF410 PE=4 SV=2 CANONICAL=A0A1D5PH29-1" }, "locus": { "chromosome": "5", "start_pos": 37195763, "end_pos": 37181331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015519.1", "url": "https://www.ensembl.org/id/ENSGALT00010015519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009052.1", "url": "https://www.ensembl.org/id/ENSGALP00010009052.1" } ] } }, { "isoform_ac": "A0A8V0XQT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQT6/entry", "sequence": { "sequence": "MDLFCVHLFPYSCVCSALIHLDPLLFLSLAFFLDGVLCHLPDLLVQFVQNTSIPLAQGLVESEPKDITCLSLLPVTETSECNRLMLPDDERDLTSPSHANSSKDVSSSAVLRSLQVNVGPDGEETRAQNVQKPSELLSSPETSSLLQDLQPSDSTSFILLNLTRAGLGSPAEHLVFVQDEVEDSGNDFLSHDSTDSSTPWFLRVQELAHDSLIAATRAQLAKNAKASNNGENVHLCSGDGQPKDSSPIPHLSRVERKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFTCPAEGCGKSFYVLQRLKVHMRTHNGEKPFVCTELGCGKQFTTAGNLKNHLRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGVKPHQCQICGKTFSQSGIFTPARY", "length": 398, "header": "tr|A0A8V0XQT6-1|A0A1D5PH29_CHICK Computationally mapped isoform of Zinc finger protein 410 OS=Gallus gallus OX=9031 GN=ZNF410 PE=4 SV=1 CANONICAL=A0A1D5PH29-1" }, "locus": { "chromosome": "5", "start_pos": 37195693, "end_pos": 37188133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015508.1", "url": "https://www.ensembl.org/id/ENSGALT00010015508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009048.1", "url": "https://www.ensembl.org/id/ENSGALP00010009048.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423340", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3ALU5-1", "protein_name": "Zinc finger protein 410", "gene_name": "znf410", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSDELDSKPELLVEFVQNACIPLGESLEEAELKPSCVPLELPESALSHAVSPPLSDLCPERSPVLVQLQSPAAAQTPTILQELQNNDSTSYILLNLAKGLAASAEPLVFVQDEVDEAQEEVSVSGDISTPWYLRVQELAHDSLIAATRAQLARDARATANSEHLLSCASDGQKRESSPRVSSRSEKIHRCPYESCCRTFTYPAHLKYHLKTHRNDRTFRCGAEGCGKSFYVLQRLQVHMRTHNGEKPFICSENNCGKKFTTAGNLKNHRRTHTGEKPFLCEVNNCGRSFAEYSSLRKHMLVHSGEKPHVCSVCGKTFSQSGSRNVHMKKRHSGDDSSTDTGYSNIDNNGREIATCTSEALTQSSLLEEEGGVSLHHSILRTQSFCQDGTCSPAAPTDPLAALAPPHELVSMTTGHTYSDDVVTLL", "length": 426 }, "evidence": [ { "id": "A0A1D5PH29", "url": "https://omabrowser.org/oma/group/A0A1D5PH29/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HNH5-1", "protein_name": "Zinc finger protein 410", "gene_name": "Znf410", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTPNHTNSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQKSPEFLSTPESPSLLQDLQPSDSTSFILLNLTRAGLGSSAEHFVFVQDETEDSGNDFLSGESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSINGENVHLGSGDGQPKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNERSFMCPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRTHTGEKPFICEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGASGSQEQEQPAEPLMGSSLLEEASVPSKNLVSMNPQSSLGGESLNLPNTNSILGVDDEVLTEGSSRPLSSVTDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERQT", "length": 478 }, "evidence": [ { "id": "A0A1D5PH29", "url": "https://omabrowser.org/oma/group/A0A1D5PH29/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86VK4-1", "protein_name": "Zinc finger protein 410", "gene_name": "ZNF410", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQDEAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERRT", "length": 478 }, "evidence": [ { "id": "A0A1D5PH29", "url": "https://omabrowser.org/oma/group/A0A1D5PH29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BKX7-1", "protein_name": "Zinc finger protein 410", "gene_name": "Znf410", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDETPNHANSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQKSPEFLTTPESPSLLQDLQPSDSTSFILLNLTRAGLGSSAEHFVFVQDETEDSGADFLSAESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTGSNGENVHLGSGDGQPKDSGPLPQAEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNERSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGTTGSQEQDQTAEPLMGSSLLEDASVPNKNLVSMNSQSSLGGESLNLSNTNSILGVDDEVLTERASRPLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERQT", "length": 478 }, "evidence": [ { "id": "A0A1D5PH29", "url": "https://omabrowser.org/oma/group/A0A1D5PH29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH29", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PH29-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 445, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PH29-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH29" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PH29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH29" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 256, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PH31-1", "uniprot_ac": "A0A1D5PH31", "uniprot_id": "A0A1D5PH31_CHICK", "mass": { "chemical_mass": 23362.0, "monoisotopic_mass": 23362.0 }, "refseq": { "ac": "NP_001038133", "name": "transcription factor LBX2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" }, "gene_names": [ { "name": "LBX2", "type": "recommended", "evidence": [ { "id": "A0A1D5PH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31" } ] }, { "name": "LBX2", "type": "synonym", "evidence": [ { "id": "NP_001038133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" } ] }, { "name": "LBX3", "type": "synonym", "evidence": [ { "id": "NP_001038133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" } ] } ], "protein_names": [ { "name": "Ladybird homeobox 2", "type": "synonym", "evidence": [ { "id": "A0A1D5PH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31/entry#names_and_taxonomy" } ] }, { "name": "ladybird-like homeobox 3", "type": "synonym", "evidence": [ { "id": "NP_001038133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" } ] }, { "name": "transcription factor LBX2", "type": "synonym", "evidence": [ { "id": "NP_001038133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY633714.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000081.1. On Sep 23, 2021 this sequence version replaced NP_001038133.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133" } ] }, { "annotation": "Seems to be involved in the development of cranial sensory innervation from peripheral ganglia.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH31", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31#function" }, { "database": "UniProtKB", "id": "ARBA00058379", "url": "https://www.uniprot.org/uniprotkb/ARBA00058379#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH31", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LBX2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31", "locus": { "chromosome": "4", "start_pos": 90628024, "end_pos": 90631408, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006184", "url": "https://www.ensembl.org/id/ENSGALG00010006184" } ] } } ], "crossref": [ { "id": "A0A1D5PH31", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031211", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431414", "url": "https://www.ncbi.nlm.nih.gov/gene/431414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431414", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAHCNKP", "url": "https://omabrowser.org/oma/group/PAHCNKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PH31", "url": "https://www.orthodb.org/?gene=A0A1D5PH31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24336:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24336:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001038133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PH31", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PH31-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSAREAAATPPLPEERRRAALEQLPPPAHCNKPLTPFGIEDILARPSPPAHGAPPARIPEKAAGPAPPRTAPSSPLCALEELASKTFRGLELSALRAAEGRDPLSALAQRPTSKKRRKSRTAFSNQQLFELERRFVRQKYLSPADRDQLAQRLALSSAQVITWFQNRRAKLKRDLDEMRADVASLQALRLREPPPAPPGPAELSEEEIDVGA", "length": 213, "header": "tr|A0A1D5PH31-1|A0A1D5PH31_CHICK Isoform 1 of Ladybird homeobox 2 OS=Gallus gallus OX=9031 GN=LBX2 PE=4 SV=1 CANONICAL=A0A1D5PH31-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PH31-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31/entry", "sequence": { "sequence": "MTSAREAAATPPLPEERRRAALEQLPPPAHCNKPLTPFGIEDILARPSPPAHGAPPARIPEKAAGPAPPRTAPSSPLCALEELASKTFRGLELSALRAAEGRDPLSALAQRPTSKKRRKSRTAFSNQQLFELERRFVRQKYLSPADRDQLAQRLALSSAQVITWFQNRRAKLKRDLDEMRADVASLQALRLREPPPAPPGPAELSEEEIDVGA", "length": 213, "header": "tr|A0A1D5PH31-1|A0A1D5PH31_CHICK Isoform 1 of Ladybird homeobox 2 OS=Gallus gallus OX=9031 GN=LBX2 PE=4 SV=1 CANONICAL=A0A1D5PH31-1" }, "locus": { "chromosome": "4", "start_pos": 90631184, "end_pos": 90628215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014723.1", "url": "https://www.ensembl.org/id/ENSGALT00010014723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008676.1", "url": "https://www.ensembl.org/id/ENSGALP00010008676.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431414", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH31", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PH57-1", "uniprot_ac": "A0A1D5PH57", "uniprot_id": "A0A1D5PH57_CHICK", "mass": { "chemical_mass": 15224.0, "monoisotopic_mass": 15224.0 }, "refseq": { "ac": "XP_417121", "name": "protein POLR1D isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417121" }, "gene_names": [ { "name": "LOC418927", "type": "recommended", "evidence": [ { "id": "A0A1D5PH57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH57" } ] }, { "name": "LOC418927", "type": "synonym", "evidence": [ { "id": "XP_417121", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417121" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerases I and III subunit RPAC2", "type": "recommended", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417121" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC418927", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH57", "locus": {} } ], "crossref": [ { "id": "A0A1D5PH57", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039958", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039958", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418927", "url": 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] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418927", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418927", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PH57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 128, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PH57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH57" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PH78-1", "uniprot_ac": "A0A1D5PH78", "uniprot_id": "A0A1D5PH78_CHICK", "mass": { "chemical_mass": 75700.0, "monoisotopic_mass": 75700.0 }, "refseq": { "ac": "XP_015147894", "name": "terminal nucleotidyltransferase 4B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147894" }, "gene_names": [ { "name": "PAPD5", "type": "recommended", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ] }, { "name": "PAPD5", "type": "synonym", "evidence": [ { "id": "XP_015147894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147894" } ] } ], "protein_names": [ { "name": "Terminal nucleotidyltransferase 4B", "type": "recommended", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "Non-canonical poly(A) RNA polymerase PAPD5", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "PAP-associated domain-containing protein 5", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "Terminal guanylyltransferase", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "Terminal uridylyltransferase 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "Topoisomerase-related function protein 4-2", "type": "synonym", "evidence": [ { "id": "A0A1D5PH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry#names_and_taxonomy" } ] }, { "name": "terminal nucleotidyltransferase 4B", "type": "synonym", "evidence": [ { "id": "XP_015147894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147894" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147894" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAPD5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78", "locus": {} } ], "crossref": [ { "id": "A0A1D5PH78", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PH78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031851", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031851", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05402", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05402", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415733", "url": "https://www.ncbi.nlm.nih.gov/gene/415733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415733", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYRAPRA", "url": "https://omabrowser.org/oma/group/MYRAPRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PH78", "url": "https://www.orthodb.org/?gene=A0A1D5PH78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23092:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23092:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PH78-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPRIAWFQPEQLGPSNRLWMQIWETTQGVRNLYFQQQQQQEQQQQQSAPAGAGPASPPGMYRAPRADPQPDFLPLESANNQHNRGHRQASPPPGAAAWARPARGVPPAAAAAAAAAASNKRKRDNKASTFGLNYSLLLGPPGQGRAPALGDGPAARAQAGLAEPLYTGTPWKKRNYSQGVVGLHEEIIDFYKYMSPRHEEERMRMEVVNRIENVIKELWPNADVQIFGSFKTGLYLPTSDIDLVVFGKWETLPLWTLEEALRKHNVADENSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVKAAQLIKDFIKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACTPNANYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTQEVATYRDWISKQWGMQSRTESSCNGNGVTLIVDNQQLDKCNNNLAEENEALGKPRNKTSETLSKHSSNSSSGPLSSSSSTLSSSSDVDSDGTPCKTSKQLSCRQPTTNRVGSQEVSLESSQSSGKTQNSQTGNTSSNTNKSQHGSARLFRSSNKGFQGPANSSHGTSVTNKQHQGSKSHHQYFHGKKRKHKRDAALSDLCR", "length": 684, "header": "tr|A0A1D5PH78-1|A0A1D5PH78_CHICK Isoform 1 of Terminal nucleotidyltransferase 4B OS=Gallus gallus OX=9031 GN=PAPD5 PE=3 SV=1 CANONICAL=A0A1D5PH78-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PH78-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78/entry", "sequence": { "sequence": "MDPRIAWFQPEQLGPSNRLWMQIWETTQGVRNLYFQQQQQQEQQQQQSAPAGAGPASPPGMYRAPRADPQPDFLPLESANNQHNRGHRQASPPPGAAAWARPARGVPPAAAAAAAAAASNKRKRDNKASTFGLNYSLLLGPPGQGRAPALGDGPAARAQAGLAEPLYTGTPWKKRNYSQGVVGLHEEIIDFYKYMSPRHEEERMRMEVVNRIENVIKELWPNADVQIFGSFKTGLYLPTSDIDLVVFGKWETLPLWTLEEALRKHNVADENSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVKAAQLIKDFIKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACTPNANYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTQEVATYRDWISKQWGMQSRTESSCNGNGVTLIVDNQQLDKCNNNLAEENEALGKPRNKTSETLSKHSSNSSSGPLSSSSSTLSSSSDVDSDGTPCKTSKQLSCRQPTTNRVGSQEVSLESSQSSGKTQNSQTGNTSSNTNKSQHGSARLFRSSNKGFQGPANSSHGTSVTNKQHQGSKSHHQYFHGKKRKHKRDAALSDLCR", "length": 684, "header": "tr|A0A1D5PH78-1|A0A1D5PH78_CHICK Isoform 1 of Terminal nucleotidyltransferase 4B OS=Gallus gallus OX=9031 GN=PAPD5 PE=3 SV=1 CANONICAL=A0A1D5PH78-1" }, "locus": { "chromosome": "11", "start_pos": 6272655, "end_pos": 6237977, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058692.1", "url": "https://www.ensembl.org/id/ENSGALT00010058692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035684.1", "url": "https://www.ensembl.org/id/ENSGALP00010035684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S9R3-1", "protein_name": "Terminal nucleotidyltransferase 4B", "gene_name": "TENT4B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "VRPHPASGARKLRLGGTRVRGALTPSGGASGGGGGGGSSTATGGSGSSTGSPSGAAPAPAPAGMYRSGERLLGGHAQPAEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPSPSASPSPHSSTAVPAAEPADPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAPGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPEPSCNGNGVTLIVDTQQLDKCNNNLSEENEALGKCRSKTSESISKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPSTGNRVGSQDVSLESSQTGGKMQSTQTTNTPNSTNKSQHGSTRLFRSSSKGFQGTTQTSHGSLMTNKQHQGKSNNQYYHGKKRKHKRDAPLSDLCR", "length": 696 }, "evidence": [ { "id": "A0A1D5PH78", "url": "https://omabrowser.org/oma/group/A0A1D5PH78/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LJG4-1", "protein_name": "Terminal nucleotidyltransferase 4B", "gene_name": "Tent4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPRIAWFQPEQLGPSNSLWMQIWETTQGLRNLYFNHHCHSSGASSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPVPSAPSSPRPAAPLPASESADPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKCYPNNETESILGRIIRVTDEVTTYRDWISKQWGLQNRPEPSCNGNGVTLIVETQQLDKCNNNLSEENEAPGKCRSKASESLSKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSSSKGFQGTAQTSHGALMTSKQHPGKSNTQCYHGKKRRHKRDAPLSELCR", "length": 700 }, "evidence": [ { "id": "A0A1D5PH78", "url": "https://omabrowser.org/oma/group/A0A1D5PH78/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68ED3-1", "protein_name": "Terminal nucleotidyltransferase 4B", "gene_name": "Tent4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQPAAWARRASAGPSASPVPSAPSSPRPAAALPASESTDPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPEPSCNGNGVTLIVDTQQLDKCNNNLSEEKEALGKCRSNASEPLSKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPPTVTRVGSQDVSLEVSQAVGKMQSTQTTNTPNNANKSQHGSARLFRSSSKGFQGTAQTSHGALMTSKQHQGKSNTQYYHGKKRRHKRDAPLSELCR", "length": 633 }, "evidence": [ { "id": "A0A1D5PH78", "url": "https://omabrowser.org/oma/group/A0A1D5PH78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDF8-1", "protein_name": "Terminal nucleotidyltransferase 4B", "gene_name": "TENT4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRSGERLLGSHALPAEQRDFLPLETTNNNNNHHQPGAWARRAGSSASSPPSASSSPHPSAAVPAADPADSASGSSNKRKRDNKASGGRAAGGGRADGGGVVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPEPSCNGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPSTGNRVGSQDVSLESSQAVGKMQSTQTTNTSNSTNKSQHGSARLFRSSSKGFQGTTQTSHGSLMTNKQHQGKSNNQYYHGKKRKHKRDAPLSDLCR", "length": 572 }, "evidence": [ { "id": "A0A1D5PH78", "url": "https://omabrowser.org/oma/group/A0A1D5PH78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "guanylyltransferase activity", "id": "GO:0070568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070568", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "positive regulation of 3'-UTR-mediated mRNA stabilization", "id": "GO:1905870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905870", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060212", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" }, { "name": "polyadenylation-dependent ncRNA catabolic process", "id": "GO:0043634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PH78", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PH78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": 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"A0A1D5PHF8-1", "uniprot_ac": "A0A1D5PHF8", "uniprot_id": "A0A1D5PHF8_CHICK", "mass": { "chemical_mass": 18843.0, "monoisotopic_mass": 18843.0 }, "refseq": { "ac": "NP_001264586", "name": "calcium channel flower homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586" }, "gene_names": [ { "name": "CACFD1", "type": "recommended", "evidence": [ { "id": "A0A1D5PHF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ] }, { "name": "C17H9ORF7", "type": "synonym", "evidence": [ { "id": "NP_001264586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586" } ] }, { "name": "C9orf7", "type": "synonym", "evidence": [ { "id": "NP_001264586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586" } ] }, { "name": "CACFD1", "type": "synonym", "evidence": [ { "id": "NP_001264586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586" } ] }, { "name": "D9S2135", 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"##Evidence-Data-START## Transcript exon combination :: SRR13267655.161702.1, HAEL01009463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Apr 13, 2013 this sequence version replaced XP_415434.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACFD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8", "locus": { "chromosome": "17", "start_pos": 7543149, "end_pos": 7533627, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028870", "url": "https://www.ensembl.org/id/ENSGALG00010028870" } ] } } ], "crossref": [ { "id": "A0A1D5PHF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHF8", "database": "AlphaFoldDB", 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13314:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13314:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSQDEQFQAAAPESASSSADDGMTWWYRWLCRIAGVIGGVSCAVAGLWNCVTINPLNIAAGVWMMLNAFVLFLCEAPFCCQFIEFANAVSARADKLRAWQKAAFYCGMAVFPVMLSLTLTTLFGNAIAFATGVLYGLSALGKKGDAISYARIHQQQKQMDEEKLTGCLEGQAL", "length": 174, "header": "tr|A0A1D5PHF8-1|A0A1D5PHF8_CHICK Isoform 1 of Calcium channel flower domain containing 1 OS=Gallus gallus OX=9031 GN=CACFD1 PE=3 SV=1 CANONICAL=A0A1D5PHF8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8/entry", "sequence": { "sequence": "MSSQDEQFQAAAPESASSSADDGMTWWYRWLCRIAGVIGGVSCAVAGLWNCVTINPLNIAAGVWMMLNAFVLFLCEAPFCCQFIEFANAVSARADKLRAWQKAAFYCGMAVFPVMLSLTLTTLFGNAIAFATGVLYGLSALGKKGDAISYARIHQQQKQMDEEKLTGCLEGQAL", "length": 174, "header": "tr|A0A1D5PHF8-1|A0A1D5PHF8_CHICK Isoform 1 of Calcium channel flower domain containing 1 OS=Gallus gallus OX=9031 GN=CACFD1 PE=3 SV=1 CANONICAL=A0A1D5PHF8-1" }, "locus": { "chromosome": "17", "start_pos": 7538940, "end_pos": 7533895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069832.1", "url": "https://www.ensembl.org/id/ENSGALT00010069832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042958.1", "url": 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"Mus musculus", "sequence": { "sequence": "MSGSGAAGAAAGPAPPAQEEGMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLNIAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL", "length": 171 }, "evidence": [ { "id": "A0A1D5PHF8", "url": "https://omabrowser.org/oma/group/A0A1D5PHF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHF8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PHF8-F1", "pdb_chain": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426700" }, "gene_names": [ { "name": "FAM43A", "type": "recommended", "evidence": [ { "id": "A0A1D5PHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0" } ] }, { "name": "FAM43A", "type": "synonym", "evidence": [ { "id": "XP_426700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426700" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 43 member A", "type": "synonym", "evidence": [ { "id": "A0A1D5PHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0/entry#names_and_taxonomy" } ] }, { "name": "protein FAM43A", "type": "synonym", "evidence": [ { "id": "XP_426700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426700" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426700.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426700" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHW0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM43A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0", "locus": { "chromosome": "9", "start_pos": 12497507, "end_pos": 12500207, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018604", "url": "https://www.ensembl.org/id/ENSGALG00010018604" } ] } } ], "crossref": [ { "id": "A0A1D5PHW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041898", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041898", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429145", "url": "https://www.ncbi.nlm.nih.gov/gene/429145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429145", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMHLECG", "url": "https://omabrowser.org/oma/group/AMHLECG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHW0", "url": "https://www.orthodb.org/?gene=A0A1D5PHW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PHW0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPWKRSKVELVAGEARRQSKPKGYAVSVHYSALTSLARACPESALHRVGSMFRSKRRKFRVTSEDPTYTVLYLGNATTIQSKGEGCTDLAVCKIWSKSEAGRQGTKMKLTISAQGIRMAHAEDKGLRRPGHLYLLHRVTYCVADPRLPRVFAWIYRHELKHKAVMLRCHAVLVSKPEKAKAMALLLYQTSATALAEFRRLKKRDDARHQQQQLVGEQSIPLVPLRKLLNGQCCYKPPVERSRSAPKLGSITEDLLGEEQEERAMHCDCEDILEALGEPEGELLRAGAGRGEGPELGRLLRDLGELSLGNDLRSLRADLGVRRLLSGESTGSESSLESTGPDGAAPPCNGADQPPPGDPESG", "length": 362, "header": "tr|A0A1D5PHW0-1|A0A1D5PHW0_CHICK Isoform 1 of Family with sequence similarity 43 member A OS=Gallus gallus OX=9031 GN=FAM43A PE=4 SV=1 CANONICAL=A0A1D5PHW0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHW0/entry", "sequence": { "sequence": "MLPWKRSKVELVAGEARRQSKPKGYAVSVHYSALTSLARACPESALHRVGSMFRSKRRKFRVTSEDPTYTVLYLGNATTIQSKGEGCTDLAVCKIWSKSEAGRQGTKMKLTISAQGIRMAHAEDKGLRRPGHLYLLHRVTYCVADPRLPRVFAWIYRHELKHKAVMLRCHAVLVSKPEKAKAMALLLYQTSATALAEFRRLKKRDDARHQQQQLVGEQSIPLVPLRKLLNGQCCYKPPVERSRSAPKLGSITEDLLGEEQEERAMHCDCEDILEALGEPEGELLRAGAGRGEGPELGRLLRDLGELSLGNDLRSLRADLGVRRLLSGESTGSESSLESTGPDGAAPPCNGADQPPPGDPESG", "length": 362, "header": "tr|A0A1D5PHW0-1|A0A1D5PHW0_CHICK Isoform 1 of Family with sequence similarity 43 member A OS=Gallus gallus OX=9031 GN=FAM43A PE=4 SV=1 CANONICAL=A0A1D5PHW0-1" }, "locus": { "chromosome": "9", "start_pos": 12499964, "end_pos": 12498879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045011.1", "url": "https://www.ensembl.org/id/ENSGALT00010045011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026887.1", "url": "https://www.ensembl.org/id/ENSGALP00010026887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429145", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429145", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BFN0-1", "protein_name": "Family with sequence similarity 43 member A", "gene_name": "FAM43A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQQEQELQEEEEEEHAEGCPEEEEDRAGEGEPAEPEAEAKRALVVAMHFECGDLLDTLESGHEEALGGGGVSPGPEAGSSPLLLGSTSDMRAELSQLINDLGELSFGNDVRSLQADLRVTRLLSGESTGSESSIEGGGPDANTATAGDPSGPADCASPDEPHSG", "length": 423 }, "evidence": [ { "id": "A0A1D5PHW0", "url": "https://omabrowser.org/oma/group/A0A1D5PHW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SFG1-1", "protein_name": "Family with sequence similarity 43 member A", "gene_name": "FAM43A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQQEQEQELQEEEEEEHTDGCLNEEEEDRAGEGGPAEQEAEAPQELVVAMHFECGDLLETLESSREEALGEGGVSPGPEAGPPPLLLGSASDMKAELSQLINDLGELSFGNDVRSLQADLRVTRLLSGESTGSESSIEGGGPDATTATTEDQSTDCGSPDEPLSG", "length": 424 }, "evidence": [ { "id": "A0A1D5PHW0", "url": "https://omabrowser.org/oma/group/A0A1D5PHW0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BUP8-1", "protein_name": "Protein FAM43A", "gene_name": "Fam43a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQQEEELQEEEEEHLEDCLEEEEEEDGVGDGDPAEEEAEAQRALVVAMQLECEDLLDPLENGHEEALGDGGVSLGPSSGTSLPLSVCASDMKAQLSQLISDLGDLSFGNDVSTLETDLRVTRLLSGESTGSESSIEGGGLDATPVSPGNPSGPADSTSLDEPYSG", "length": 424 }, "evidence": [ { "id": "A0A1D5PHW0", "url": "https://omabrowser.org/oma/group/A0A1D5PHW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N2R8-1", "protein_name": "Protein FAM43A", "gene_name": "FAM43A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDLGELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADEPHSG", "length": 423 }, "evidence": [ { "id": "A0A1D5PHW0", "url": "https://omabrowser.org/oma/group/A0A1D5PHW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PHW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 362, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PHW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHW0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PHX7-1", "uniprot_ac": "A0A1D5PHX7", "uniprot_id": "A0A1D5PHX7_CHICK", "mass": { "chemical_mass": 19994.0, "monoisotopic_mass": 19994.0 }, "refseq": { "ac": "XP_001232488", "name": "uncharacterized protein C15orf62 homolog, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232488" }, "gene_names": [ { "name": "C15orf62", "type": "recommended", "evidence": [ { "id": "A0A1D5PHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ] }, { "name": "C15orf62", "type": "synonym", "evidence": [ { "id": "XP_001232488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232488" } ] } ], "protein_names": [ { "name": "Chromosome 15 open reading frame 62", "type": "synonym", "evidence": [ { "id": "A0A1D5PHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C15orf62 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_001232488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232488" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232488" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C15orf62", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7", "locus": { "chromosome": "5", "start_pos": 1198417, "end_pos": 1194767, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023067", "url": "https://www.ensembl.org/id/ENSGALG00010023067" } ] } } ], "crossref": [ { "id": "ENSGALG00000040929", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040929", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770534", "url": "https://www.ncbi.nlm.nih.gov/gene/770534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770534", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKKLGNQ", "url": "https://omabrowser.org/oma/group/HKKLGNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PHX7", "url": "https://www.orthodb.org/?gene=A0A1D5PHX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15344:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15344:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTWRRGSIKSTTFFRRFSLRRHKKLGNQVIILNKNSHTLDSDGQCQKRECLRDLKDKSDYLSCQSEQNLAKAQAPPKPPRLYLDSSSCPNIIDHTDSHSDVSFSDSSHQYNKATQTQFHKDQATDCVTSEPGSQNGTTLSDLSDPFLSFKVDLGLSLLEDVLQTLRKQNPRDYAI", "length": 176, "header": "tr|A0A1D5PHX7-1|A0A1D5PHX7_CHICK Isoform 1 of Chromosome 15 open reading frame 62 OS=Gallus gallus OX=9031 GN=C15orf62 PE=4 SV=2 CANONICAL=A0A1D5PHX7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7/entry", "sequence": { "sequence": "MDTWRRGSIKSTTFFRRFSLRRHKKLGNQVIILNKNSHTLDSDGQCQKRECLRDLKDKSDYLSCQSEQNLAKAQAPPKPPRLYLDSSSCPNIIDHTDSHSDVSFSDSSHQYNKATQTQFHKDQATDCVTSEPGSQNGTTLSDLSDPFLSFKVDLGLSLLEDVLQTLRKQNPRDYAI", "length": 176, "header": "tr|A0A1D5PHX7-1|A0A1D5PHX7_CHICK Isoform 1 of Chromosome 15 open reading frame 62 OS=Gallus gallus OX=9031 GN=C15orf62 PE=4 SV=2 CANONICAL=A0A1D5PHX7-1" }, "locus": { "chromosome": "5", "start_pos": 1195418, "end_pos": 1194891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056167.1", "url": "https://www.ensembl.org/id/ENSGALT00010056167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033986.1", "url": "https://www.ensembl.org/id/ENSGALP00010033986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770534", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BFH1-1", "protein_name": "Chromosome 1 C15orf62 homolog", "gene_name": "C15orf62", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METWRKGSFRSASFFKRLSLGRPRRLRRQGSVLSQASTAGGDHEEYSNREVIRELRGRPDGRRLPLWGDEQPRVTLLAPPKPPRLYRESSSCPNILEPPSAYTAAYSATLPSALSLAEALHQYTEEELLDTPPCQRTPAPDLSDPFFSFQVDLGISLLEEVLQMLREQFPSESSF", "length": 175 }, "evidence": [ { "id": "A0A1D5PHX7", "url": "https://omabrowser.org/oma/group/A0A1D5PHX7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A1S9-1", "protein_name": "Similar to human chromosome 15 open reading frame 62", "gene_name": "C3h15orf62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLRNSMETWRKGSFRNASFFKRITLGRPRRLQRQGSVLSQASTAGGDHEEYSNREVIRELRGRPDGRRLPLWGDEHPRATLLAPPKPPRLYRESSSCPNILEPPATYTTAYSATLPSAISLTGPLHQCSEEGLLDTPHFPRTPTPDLSDPFFSFKVDLGLSLLEEVLQILKEQFPSEPHF", "length": 181 }, "evidence": [ { "id": "A0A1D5PHX7", "url": "https://omabrowser.org/oma/group/A0A1D5PHX7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9T249-1", "protein_name": "Chromosome 10 C15orf62 homolog", "gene_name": "C10H15orf62", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METWRKGSFRSPSFFKRLSLGRPRRLRRQGSVLSQASTAGGDHEEYSNREVIRELRGRPDGRRLPLWGDEQPRATLLAPPKPPRLYRESFSCPNILEAPSAEYTAAYSATLPSALSVADNLHRSSEEDLTDTPPFQRTPAPDLSDPFFSFKVDLGISLLEEVLQMLREQFPSELSF", "length": 176 }, "evidence": [ { "id": "A0A1D5PHX7", "url": "https://omabrowser.org/oma/group/A0A1D5PHX7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A8K5M9-1", "protein_name": "Uncharacterized protein C15orf62, mitochondrial", "gene_name": "C15orf62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METWRKGSFRNASFFKQLSLGRPRRLRRQSSVLSQASTAGGDHEEYSNREVIRELQGRPDGRRLPLWGDEQPRATLLAPPKPPRLYRESSSCPNILEPPPAYTAAYSATLPSALSLSSALHQHSEKGLVDTPCFQRTPTPDLSDPFLSFKVDLGISLLEEVLQMLREQFPSEPSF", "length": 175 }, "evidence": [ { "id": "A0A1D5PHX7", "url": "https://omabrowser.org/oma/group/A0A1D5PHX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHX7", "url": 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"UniProtKB", "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ], "pmid": "" }, { "name": "positive regulation of pseudopodium assembly", "id": "GO:0031274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031274", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHX7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHX7" }, { "id": "PF14957", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14957" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cdc42 effector-like", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 167, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PHZ3-1", "uniprot_ac": "A0A1D5PHZ3", "uniprot_id": "A0A1D5PHZ3_CHICK", "mass": { "chemical_mass": 7832.0, "monoisotopic_mass": 7832.0 }, "refseq": { "ac": "NP_001129654", "name": "heat shock factor-binding protein 1-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129654" }, "gene_names": [ { "name": "HSBP1L1", "type": "recommended", "evidence": [ { "id": "A0A1D5PHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3" } ] }, { "name": "HSBP1L1", "type": "synonym", "evidence": [ { "id": "NP_001129654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129654" } ] } ], "protein_names": [ { "name": "Heat shock factor binding protein 1 like 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3/entry#names_and_taxonomy" } ] }, { "name": "heat shock factor-binding protein 1-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001129654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129654" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01204427.1, BX932365.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992533 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000039.1. On Oct 26, 2008 this sequence version replaced XP_429790.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001129654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129654" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSBP1L1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3", "locus": { "chromosome": "2", "start_pos": 55908704, "end_pos": 55918155, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008162", "url": "https://www.ensembl.org/id/ENSGALG00010008162" } ] } } ], "crossref": [ { "id": "A0A1D5PHZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039326", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420812", "url": "https://www.ncbi.nlm.nih.gov/gene/420812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420812", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420812", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEEMGHR", "url": "https://omabrowser.org/oma/group/MEEMGHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19424:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19424:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001129654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGEPLGAECLSQLAENLLHQLQENFQALTERITLRMEEMGERINDLEKHVADLMAEAGIENTDDGLRH", "length": 70, "header": "tr|A0A1D5PHZ3-1|A0A1D5PHZ3_CHICK Isoform 1 of Heat shock factor binding protein 1 like 1 OS=Gallus gallus OX=9031 GN=HSBP1L1 PE=3 SV=1 CANONICAL=A0A1D5PHZ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3/entry", "sequence": { "sequence": "MAAGEPLGAECLSQLAENLLHQLQENFQALTERITLRMEEMGERINDLEKHVADLMAEAGIENTDDGLRH", "length": 70, "header": "tr|A0A1D5PHZ3-1|A0A1D5PHZ3_CHICK Isoform 1 of Heat shock factor binding protein 1 like 1 OS=Gallus gallus OX=9031 GN=HSBP1L1 PE=3 SV=1 CANONICAL=A0A1D5PHZ3-1" }, "locus": { "chromosome": "2", "start_pos": 55911500, "end_pos": 55909078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019474.1", "url": "https://www.ensembl.org/id/ENSGALT00010019474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011022.1", "url": "https://www.ensembl.org/id/ENSGALP00010011022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420812", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420812", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RXB2-1", "protein_name": "Heat shock factor-binding protein 1-like protein 1", "gene_name": "Hsbp1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTRTPEVPCGDLLQNAAENLLLEVEEHFQALTTTLNLRMEEMGSRIEDLQRNVDDLMTQAGIENSIKEPAT", "length": 72 }, "evidence": [ { "id": "A0A1D5PHZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PHZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C9JCN9-1", "protein_name": "Heat shock factor-binding protein 1-like protein 1", "gene_name": "HSBP1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVRGPEAPGGRALRDAAENLFQELQEHFQALTATLNLRMEEMGNRIEDLQKNVKDLMVQAGIENSIKEQMLKT", "length": 74 }, "evidence": [ { "id": "A0A1D5PHZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PHZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A9E1-1", "protein_name": "Heat shock factor-binding protein 1-like protein 1", "gene_name": "Hsbp1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDARTPEVPCGDLLQNAAENLLQEVEEHFQALTATLNLRMEEMGNRIEDLQRNVDDLMAQAGIENSIKEATT", "length": 72 }, "evidence": [ { "id": "A0A1D5PHZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PHZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PHZ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 70, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PHZ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PHZ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PI14-1", "uniprot_ac": "A0A1D5PI14", "uniprot_id": "A0A1D5PI14_CHICK", "mass": { "chemical_mass": 56396.0, "monoisotopic_mass": 56396.0 }, "refseq": {}, "gene_names": [ { "name": "TBLX1", "type": "recommended", "evidence": [ { "id": "A0A1D5PI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14" } ] } ], "protein_names": [ { "name": "Transducin beta like X1", "type": "synonym", "evidence": [ { "id": "A0A1D5PI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14#function" }, { "database": "UniProtKB", "id": "ARBA00056890", "url": "https://www.uniprot.org/uniprotkb/ARBA00056890#function" }, { "database": "UniProtKB", "id": "A0A8V0X2X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2X1#function" }, { "database": "UniProtKB", "id": "A0A8V0X649", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X649#function" }, { "database": "UniProtKB", "id": "A0A8V0X983", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X983#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBLX1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14", "locus": { "chromosome": "1", "start_pos": 125335589, "end_pos": 125535463, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001599", "url": "https://www.ensembl.org/id/ENSGALG00010001599" } ] } } ], "crossref": [ { "id": "A0A1D5PI14", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PI14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040006", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PI14", "url": "https://www.orthodb.org/?gene=A0A1D5PI14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X2X1", "url": "https://www.orthodb.org/?gene=A0A8V0X2X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X649", "url": "https://www.orthodb.org/?gene=A0A8V0X649", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X983", "url": "https://www.orthodb.org/?gene=A0A8V0X983", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-400206", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9029569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PI14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X649", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X649", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X649-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X649-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X983", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X983-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSKKCTFE", "length": 521, "header": "tr|A0A1D5PI14-1|A0A1D5PI14_CHICK Isoform 1 of Transducin beta like X1 OS=Gallus gallus OX=9031 GN=TBLX1 PE=1 SV=2 CANONICAL=A0A1D5PI14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PI14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSKKCTFE", "length": 521, "header": "tr|A0A1D5PI14-1|A0A1D5PI14_CHICK Isoform 1 of Transducin beta like X1 OS=Gallus gallus OX=9031 GN=TBLX1 PE=1 SV=2 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125340685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003659.1", "url": "https://www.ensembl.org/id/ENSGALT00010003659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002056.1", "url": "https://www.ensembl.org/id/ENSGALP00010002056.1" } ] } }, { "isoform_ac": "A0A8V0X2X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2X1/entry", "sequence": { "sequence": "MQINLCFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK", "length": 509, "header": "tr|A0A8V0X2X1-1|A0A1D5PI14_CHICK Computationally mapped isoform of Transducin beta like X1 OS=Gallus gallus OX=9031 GN=TBLX1 PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125382232, "end_pos": 125339955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003654.1", "url": "https://www.ensembl.org/id/ENSGALT00010003654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002053.1", "url": "https://www.ensembl.org/id/ENSGALP00010002053.1" } ] } }, { "isoform_ac": "A0A8V0X649-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X649/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQYIATEAPEASLKSAGMLEETKWEQAHQMDRFVF", "length": 514, "header": "tr|A0A8V0X649-1|A0A1D5PI14_CHICK Computationally mapped isoform of Transducin beta like X1 OS=Gallus gallus OX=9031 GN=TBLX1 PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125339969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003661.1", "url": "https://www.ensembl.org/id/ENSGALT00010003661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002057.1", "url": "https://www.ensembl.org/id/ENSGALP00010002057.1" } ] } }, { "isoform_ac": "A0A8V0X983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X983/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQVLF", "length": 467, "header": "tr|A0A8V0X983-1|A0A1D5PI14_CHICK Computationally mapped isoform of Transducin beta like X1 OS=Gallus gallus OX=9031 GN=TBLX1 PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125342088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003658.1", "url": "https://www.ensembl.org/id/ENSGALT00010003658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002055.1", "url": "https://www.ensembl.org/id/ENSGALP00010002055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-GGA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-GGA-9029569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029569", "resource": "Reactome", "description": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": 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"https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ] }, { "name": "SRGAP3", "type": "synonym", "evidence": [ { "id": "NP_001376204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376204" } ] } ], "protein_names": [ { "name": "SLIT-ROBO Rho GTPase-activating protein 3", "type": "recommended", "evidence": [ { "id": "A0A1D5PJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 14", "type": "synonym", "evidence": [ { "id": "A0A1D5PJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10/entry#names_and_taxonomy" } ] }, { "name": "SLIT-ROBO Rho GTPase-activating protein 3 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001376204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376204" } ] }, { "name": "WAVE-associated Rac GTPase-activating protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.87080.1, SRR13267649.175418.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Dec 8, 2020 this sequence version replaced XP_015148609.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376204" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRGAP3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10", "locus": { "chromosome": "12", "start_pos": 19516714, "end_pos": 19584828, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019624", "url": "https://www.ensembl.org/id/ENSGALG00010019624" } ] } } ], "crossref": [ { "id": "A0A1D5PJ10", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008378", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008378", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04383", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04383", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11955", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11955", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416115", "url": "https://www.ncbi.nlm.nih.gov/gene/416115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MEAFIKX", "url": "https://omabrowser.org/oma/group/MEAFIKX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJ10", "url": "https://www.orthodb.org/?gene=A0A1D5PJ10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RM91", "url": "https://www.orthodb.org/?gene=A0A1L1RM91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA44", "url": "https://www.orthodb.org/?gene=A0A8V0ZA44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVK8", "url": "https://www.orthodb.org/?gene=F1NVK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RM91", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RM91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RM91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVK8", "url": "https://www.uniprot.org/uniprotkb/F1NVK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSQGKSKKDKEIIAEYDAQVKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRGSREHQFKKDQHLLSPVNCWYLVLTQTRRESRDHATLNDIFTNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDVSVNLLRHEERPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAVSKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDARSDKHTIMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYLNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYNHKLFNGNMETFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLADDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLVSTIKTENPTERVHQIQQIIVTLPRAVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIINHEGIFPSHRELEGPVYEKCMTGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDDEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDIQSPTDHLVDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPGIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINFPDRKALSDGHPLRSTCGSTRHSSLGDQKSLEAEALAEDIEKTMSTALNELRELERQNTAKQAPDVVLDTLELLKNPPLGAANSEPASPLHTILIRDPDAAMRRSSSSTAEMMTTFKPALSARLAGAQLRPPPMRPARPAVQHRSSSSSSSGVGSPAITPTEKLFPSGADKSGTM", "length": 1099, "header": "tr|A0A1D5PJ10-1|A0A1D5PJ10_CHICK Isoform 1 of SLIT-ROBO Rho GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=SRGAP3 PE=1 SV=2 CANONICAL=A0A1D5PJ10-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10/entry", "sequence": { "sequence": "MSSQGKSKKDKEIIAEYDAQVKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRGSREHQFKKDQHLLSPVNCWYLVLTQTRRESRDHATLNDIFTNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDVSVNLLRHEERPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAVSKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDARSDKHTIMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYLNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYNHKLFNGNMETFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLADDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLVSTIKTENPTERVHQIQQIIVTLPRAVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIINHEGIFPSHRELEGPVYEKCMTGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDDEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDIQSPTDHLVDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPGIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINFPDRKALSDGHPLRSTCGSTRHSSLGDQKSLEAEALAEDIEKTMSTALNELRELERQNTAKQAPDVVLDTLELLKNPPLGAANSEPASPLHTILIRDPDAAMRRSSSSTAEMMTTFKPALSARLAGAQLRPPPMRPARPAVQHRSSSSSSSGVGSPAITPTEKLFPSGADKSGTM", "length": 1099, "header": "tr|A0A1D5PJ10-1|A0A1D5PJ10_CHICK Isoform 1 of SLIT-ROBO Rho GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=SRGAP3 PE=1 SV=2 CANONICAL=A0A1D5PJ10-1" }, "locus": { "chromosome": "12", "start_pos": 19584708, "end_pos": 19519491, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047379.1", "url": "https://www.ensembl.org/id/ENSGALT00010047379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028074.1", "url": "https://www.ensembl.org/id/ENSGALP00010028074.1" } ] } }, { "isoform_ac": "A0A1L1RM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RM91/entry", "sequence": { "sequence": "MSSQGKSKKDKEIIAEYDAQVKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRGSREHQFKKDQHLLSPVNCWYLVLTQTRRESRDHATLNDIFTNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDVSVNLLRHEERPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAVSKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDARSDKHTIMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYLNGSNLITKLQAKHDLLKQTLGEGERAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLADDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLVSTIKTENPTERVHQIQQIIVTLPRAVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIINHEGIFPSHRELEGPVYEKCMTGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDDEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDIQSPTDHLVDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPGIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINFPDRKALSDGHPLRSTCGSTRHSSLGDQKSLEAEALAEDIEKTMSTALNELRELERQNTAKQAPDVVLDTLELLKNPPLGAANSEPASPLHTILIRDPDAAMRRSSSSTAEMMTTFKPALSARLAGAQLRPPPMRPARPAVQHRSSSSSSSGVGSPAITPTEKLFPSGADKSGTM", "length": 1075, "header": "tr|A0A1L1RM91-1|A0A1L1RM91_CHICK Computationally mapped isoform of SLIT-ROBO Rho GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=SRGAP3 PE=1 SV=2 CANONICAL=A0A1D5PJ10-1" }, "locus": { "chromosome": "12", "start_pos": 19584708, "end_pos": 19519491, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047388.1", "url": "https://www.ensembl.org/id/ENSGALT00010047388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028079.1", "url": "https://www.ensembl.org/id/ENSGALP00010028079.1" } ] } }, { "isoform_ac": "A0A8V0ZA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA44/entry", "sequence": { "sequence": "MSSQGKSKKDKEIIAEYDAQVKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRGSREHQFKKDQHLLSPVNCWYLVLTQTRRESRDHATLNDIFTNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDVSVNLLRHEERPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAVSKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDARSDKHTIMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYLNGSNLITKLQAKHDLLKQTLGEGESPPCLPPKPQKMRRPRPLSVYNHKLFNGNMETFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERDPLADDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLVSTIKTENPTERVHQIQQIIVTLPRAVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIINHEGIFPSHRELEGPVYEKCMTGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDDEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDIQSPTDHLVDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPGIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINFPDRKALSDGHPLRSTCGSTRHSSLGDQKSLEAEALAEDIEKTMSTALNELRELERQNTAKQAPDVVLDTLELLKNPPLGAANSEPASPLHTILIRDPDAAMRRSSSSTAEMMTTFKPALSARLAGAQLRPPPMRPARPAVQHRSSSSSSSGVGSPAITPTEKLFPSGADKSGTM", "length": 1090, "header": "tr|A0A8V0ZA44-1|A0A8V0ZA44_CHICK Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=SRGAP3 PE=1 SV=1 CANONICAL=A0A1D5PJ10-1" }, "locus": { "chromosome": "12", "start_pos": 19584708, "end_pos": 19519491, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047352.1", "url": "https://www.ensembl.org/id/ENSGALT00010047352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028059.1", "url": "https://www.ensembl.org/id/ENSGALP00010028059.1" } ] } }, { "isoform_ac": "F1NVK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVK8/entry", "sequence": { "sequence": "MSSQGKSKKDKEIIAEYDAQVKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRGSREHQFKKDQHLLSPVNCWYLVLTQTRRESRDHATLNDIFTNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDVSVNLLRHEERPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAVSKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDARSDKHTIMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYLNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYNHKLFNGNMETFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLADDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLVSTIKTENPTERVHQIQQIIVTLPRAVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIINHEGIFPSHRELEGPVYEKCMTGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDDEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDIQSPTDHLVDYGFGGVMGRTSRRP", "length": 858, "header": "tr|F1NVK8-1|A0A1D5PJ10_CHICK Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=SRGAP3 PE=1 SV=3 CANONICAL=A0A1D5PJ10-1" }, "locus": { "chromosome": "12", "start_pos": 19584708, "end_pos": 19519886, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047362.1", "url": "https://www.ensembl.org/id/ENSGALT00010047362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028064.1", "url": "https://www.ensembl.org/id/ENSGALP00010028064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IAE2-1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "srgap3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSQTKIKKDKEIIAEYETQVKEIRNQLVEQFKCLEQQSEARIQLLQDLQEFFRRKAEIQLEYSRSLEKLAERFSSKIRGPRKEQHLLSSVNCWYLVLNQTRRESRDHATLNDIYINNVIVRLAQISEDVIRLFKKSKEIGIQMHEELVKVTNELYTVMKTYHMYHTESISAESKLKDAEKQEEKQFSKSGDLNVNLLRHEDRPQRRSSVRKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAVVAKYYIHDVSDMIDCCDLGYHASLARTLRTYLSAEYNLETSRHEGLDIIENAVDNLDPRSDKHKIMDMYNQVFCPPMRFEFLPHMGDEVCQVSAQQPVQTELLMRFHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESIKSVASESYMSKLNIAKRRANQQETEVFYFTKFKEYLNGSNLIIKLQAKHDLLKQTLGEGERAECGTTRPPTLPPKPQKLRKPRPRSVYNHKLFNGNMESFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQSDHDINSVAGVLKLYFRGLENPLFPKERFLDMISTVKLESSAERAHHIQQIIVTLPRTVIIVLRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPIPDGQDPVACQAHVNEVIKTIIMHNEIIFPSPRELDGPVYEKCMTGGEEYCDSPHSEPGTIDEADNCTEPHTSDDEVEQIEAIAKFDYMGRTPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDLDDAFSDSLSQKADSEASSGPLLDDKASSKNDLHSPCEPSADYNFSGVMGRVRLRSDGSAIPRRRSGTDSHSPPRDTPPRAAACPSSPHKVAVNRSHIESPEKRRLGTFGSAGSINYPERKIYPEGHPLRPVPGATRHSSLGDHKSLEAEALAEDIEKTMNTALHELRELERQNTAKQAPDVVLDTLEPLKNPVSSEPASPLHTIMIRDPDAALRRSSSSTSEMMTTFKPALSARLAGAQLRPPPMRPVRPPPTQHRSSSSSSSGVGSPAITPTEKIFPNNPSNAAASSANSGEKPGTM", "length": 1094 }, "evidence": [ { "id": "A0A1D5PJ10", "url": "https://omabrowser.org/oma/group/A0A1D5PJ10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I6GHT9-1", "protein_name": "SLIT-ROBO Rho GTPase activating protein 3", "gene_name": "Srgap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDIIENAVDNLDSRSDKHTVMDMCSQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESIKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTSRRDGRLRLPHFPWLSCPPAPHFVPHPAFQGRRNARTRNQDSGQAIPLVVESCIRFINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPADRVHPIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINYPDKKALTEGLSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPISSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSSDKSGTM", "length": 1104 }, "evidence": [ { "id": "A0A1D5PJ10", "url": "https://omabrowser.org/oma/group/A0A1D5PJ10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJI3-1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "SRGAP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVCSHKLFNGCMETFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPISSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM", "length": 1099 }, "evidence": [ { "id": "A0A1D5PJ10", "url": "https://omabrowser.org/oma/group/A0A1D5PJ10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43295-1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "SRGAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM", "length": 1099 }, "evidence": [ { "id": "A0A1D5PJ10", "url": "https://omabrowser.org/oma/group/A0A1D5PJ10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q812A2-1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "Srgap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGELSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCSQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESIKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVAESCIRFINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPADRVHPIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGTIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLSRGRIESPEKRRMATFGSAGSINYPDKKALTEGLSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPISSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSSDKSGTM", "length": 1099 }, "evidence": [ { "id": "A0A1D5PJ10", "url": "https://omabrowser.org/oma/group/A0A1D5PJ10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJ10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1099, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJ10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 733, "end_pos": 735 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJ35-1", "uniprot_ac": "A0A1D5PJ35", "uniprot_id": "A0A1D5PJ35_CHICK", "mass": { "chemical_mass": 28392.0, "monoisotopic_mass": 28392.0 }, "refseq": { "ac": "NP_001264615", "name": "transmembrane protein 41A isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264615" }, "gene_names": [ { "name": "TMEM41A", "type": "recommended", "evidence": [ { "id": "A0A1D5PJ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35" } ] }, { "name": "TMEM41A", "type": "synonym", "evidence": [ { "id": "NP_001264615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264615" } ] } ], "protein_names": [ { "name": "Transmembrane protein 41A", "type": "synonym", "evidence": [ { "id": "A0A1D5PJ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 41A isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001264615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264615" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU124186.1, BU472279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AM066169.1, BI066723.1, BU124186.1, BU276858.1 and BU338654.1. On Apr 13, 2013 this sequence version replaced XP_422688.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264615" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ35", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM41A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35", "locus": { "chromosome": "9", "start_pos": 3308588, "end_pos": 3311530, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024524", "url": "https://www.ensembl.org/id/ENSGALG00010024524" } ] } } ], "crossref": [ { "id": "A0A1D5PJ35", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ35", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006649", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006649", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424875", "url": "https://www.ncbi.nlm.nih.gov/gene/424875", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424875", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424875", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PJ35", "url": "https://www.orthodb.org/?gene=A0A1D5PJ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43220:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43220:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ35", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRRPAGLLLVFAGSTAALWLLSARLGAGRTGRPLRFPSDLEELRELAEALRDYERRHRGAAVALFCAAYLYKQSFAIPGSSLLNVLAGALFGPWVGLALCSALTSVGATCCYLLSAAFGKRVVVRCFPDKVALLQGKVEENRSCLFFFLLFLRLFPMTPNWFLNLSAPILNIPLSQFFFSVLIGLTPYNFICVQTGAILSQINSLDAIFSWDTLLKLLLMAMAALVPGTLIKKYSKKHLKLDEDEHAPLLNGKKSM", "length": 257, "header": "tr|A0A1D5PJ35-1|A0A1D5PJ35_CHICK Isoform 1 of Transmembrane protein 41A OS=Gallus gallus OX=9031 GN=TMEM41A PE=3 SV=2 CANONICAL=A0A1D5PJ35-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35/entry", "sequence": { "sequence": "MWRRPAGLLLVFAGSTAALWLLSARLGAGRTGRPLRFPSDLEELRELAEALRDYERRHRGAAVALFCAAYLYKQSFAIPGSSLLNVLAGALFGPWVGLALCSALTSVGATCCYLLSAAFGKRVVVRCFPDKVALLQGKVEENRSCLFFFLLFLRLFPMTPNWFLNLSAPILNIPLSQFFFSVLIGLTPYNFICVQTGAILSQINSLDAIFSWDTLLKLLLMAMAALVPGTLIKKYSKKHLKLDEDEHAPLLNGKKSM", "length": 257, "header": "tr|A0A1D5PJ35-1|A0A1D5PJ35_CHICK Isoform 1 of Transmembrane protein 41A OS=Gallus gallus OX=9031 GN=TMEM41A PE=3 SV=2 CANONICAL=A0A1D5PJ35-1" }, "locus": { "chromosome": "9", "start_pos": 3311447, "end_pos": 3309871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059826.1", "url": "https://www.ensembl.org/id/ENSGALT00010059826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036586.1", "url": "https://www.ensembl.org/id/ENSGALP00010036586.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424875", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424875", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ35", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJ35-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJ35-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ35" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PJ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ35" }, { "id": "PF09335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VTT", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 198, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 165, "end_pos": 167 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJ64-1", "uniprot_ac": "A0A1D5PJ64", "uniprot_id": "A0A1D5PJ64_CHICK", "mass": { "chemical_mass": 9908.0, "monoisotopic_mass": 9908.0 }, "refseq": { "ac": "XP_040521178", "name": "feather keratin 1-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521178" }, "gene_names": [ { "name": "LOC121110022", "type": "recommended", "evidence": [ { "id": "A0A1D5PJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64" } ] }, { "name": "LOC121110022", "type": "synonym", "evidence": [ { "id": "XP_040521178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521178" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A1D5PJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64/entry#names_and_taxonomy" } ] }, { "name": "feather keratin 1-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040521178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521178" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040521178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521178" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ64", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121110022", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64", "locus": {} } ], "crossref": [ { "id": "A0A1D5PJ64", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033622", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033622", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "121110022", "url": "https://www.ncbi.nlm.nih.gov/gene/121110022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857710", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857710", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "gga:100858444", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PJ64", "url": "https://www.orthodb.org/?gene=A0A1D5PJ64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040521178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521178", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ64", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSDLCRPCGPTPLANSCNEPCVRQCQDSQVVIQPPAVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A1D5PJ64-1|A0A1D5PJ64_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121110022 PE=3 SV=1 CANONICAL=A0A1D5PJ64-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64/entry", "sequence": { "sequence": "MSCSDLCRPCGPTPLANSCNEPCVRQCQDSQVVIQPPAVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A1D5PJ64-1|A0A1D5PJ64_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121110022 PE=3 SV=1 CANONICAL=A0A1D5PJ64-1" }, "locus": { "chromosome": "2", "start_pos": 147819454, "end_pos": 147819161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022839.1", "url": "https://www.ensembl.org/id/ENSGALT00010022839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013199.1", "url": "https://www.ensembl.org/id/ENSGALP00010013199.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857710", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857710", "resource": "KEGG Pathway" }, { "id": "gga:100858444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858444", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ64", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJ64", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJ64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJ64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 98, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJ64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJ64" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJN7-1", "uniprot_ac": "A0A1D5PJN7", "uniprot_id": "A0A1D5PJN7_CHICK", "mass": { "chemical_mass": 95678.0, "monoisotopic_mass": 95678.0 }, "refseq": { "ac": "XP_004940968", "name": "follistatin-related protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940968" }, "gene_names": [ { "name": "FSTL5", "type": "recommended", "evidence": [ { "id": "A0A1D5PJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ] }, { "name": "FSTL5", "type": "synonym", "evidence": [ { "id": "XP_004940968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940968" } ] } ], "protein_names": [ { "name": "Follistatin-related protein 5", "type": "recommended", "evidence": [ { "id": "A0A1D5PJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7/entry#names_and_taxonomy" } ] }, { "name": "Follistatin-like protein 5", "type": "synonym", "evidence": [ { "id": "A0A1D5PJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7/entry#names_and_taxonomy" } ] }, { "name": "follistatin-related protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940968" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940968" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FSTL5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7", "locus": { "chromosome": "4", "start_pos": 22253755, "end_pos": 22519557, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007901", "url": "https://www.ensembl.org/id/ENSGALG00010007901" } ] } } ], "crossref": [ { "id": "A0A1D5PJN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041736", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041736", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428726", "url": "https://www.ncbi.nlm.nih.gov/gene/428726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428726", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHAGNYT", "url": "https://omabrowser.org/oma/group/IHAGNYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJN7", "url": "https://www.orthodb.org/?gene=A0A1D5PJN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XWG6", "url": "https://www.orthodb.org/?gene=A0A8V0XWG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFMWWSAVLLLGWILFGADGWPAKEGYDFMPYQPLIRLRHKQEKNQESSRSKGYMDQDGHFKSCENKYCGLGRHCVMNGESGQAECVCMERCKPHYKPVCGSDGEFYENHCEVHRAACLKKQKVAIVHNEDCFFKGDKCKPTEYSKVKNMLLDLQNQRYAAQSKNRNVGEKMALRKLLVDQMFHYFDSDSNGLVDTNELSQVIKRDELGKDLSDCSLFDLLKYDDYNSDKHLGLEEFYRAFQIVQLSLPDDQKLSTTAATVGQSAVLSCAIQGALRPPIIWRRNNVILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYADGYDKLYQTHILEVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREQGLGIGNMFYVFYEDGIKVIQPVECEFQRHIKPSEKLLGFQDEVCPKTDGDSVQRCVWATAVNVKDKFIYVTQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVQSWGNMEKNSPTLQVITQASGSISHHTIHTQPVGKQFDRVDDFFIPATTLIITHIRFGFILHKDEPVLQKIDLETMSYIKTISLKDYNCIPQSLAYTHLGGFFFIYCKPDTTGAVLPQLIVDSVTDSVIGYNGDVTGRPHVSPDGHYLVSIDDAKGLMRIQTITMRGEILDAFDIHTNLHISDVAFQPSFTEAHQYNIYCSSSTQTDVLFVELSSGKVKMVKSLKEPVRAGEWPWNSKNRLIKDSGLFGQYLMTPSKESLFILDGRLNKLNCEITEVERGNTVIWVGEA", "length": 846, "header": "tr|A0A1D5PJN7-1|A0A1D5PJN7_CHICK Isoform 1 of Follistatin-related protein 5 OS=Gallus gallus OX=9031 GN=FSTL5 PE=4 SV=1 CANONICAL=A0A1D5PJN7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7/entry", "sequence": { "sequence": "MFMWWSAVLLLGWILFGADGWPAKEGYDFMPYQPLIRLRHKQEKNQESSRSKGYMDQDGHFKSCENKYCGLGRHCVMNGESGQAECVCMERCKPHYKPVCGSDGEFYENHCEVHRAACLKKQKVAIVHNEDCFFKGDKCKPTEYSKVKNMLLDLQNQRYAAQSKNRNVGEKMALRKLLVDQMFHYFDSDSNGLVDTNELSQVIKRDELGKDLSDCSLFDLLKYDDYNSDKHLGLEEFYRAFQIVQLSLPDDQKLSTTAATVGQSAVLSCAIQGALRPPIIWRRNNVILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYADGYDKLYQTHILEVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREQGLGIGNMFYVFYEDGIKVIQPVECEFQRHIKPSEKLLGFQDEVCPKTDGDSVQRCVWATAVNVKDKFIYVTQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVQSWGNMEKNSPTLQVITQASGSISHHTIHTQPVGKQFDRVDDFFIPATTLIITHIRFGFILHKDEPVLQKIDLETMSYIKTISLKDYNCIPQSLAYTHLGGFFFIYCKPDTTGAVLPQLIVDSVTDSVIGYNGDVTGRPHVSPDGHYLVSIDDAKGLMRIQTITMRGEILDAFDIHTNLHISDVAFQPSFTEAHQYNIYCSSSTQTDVLFVELSSGKVKMVKSLKEPVRAGEWPWNSKNRLIKDSGLFGQYLMTPSKESLFILDGRLNKLNCEITEVERGNTVIWVGEA", "length": 846, "header": "tr|A0A1D5PJN7-1|A0A1D5PJN7_CHICK Isoform 1 of Follistatin-related protein 5 OS=Gallus gallus OX=9031 GN=FSTL5 PE=4 SV=1 CANONICAL=A0A1D5PJN7-1" }, "locus": { "chromosome": "4", "start_pos": 22495103, "end_pos": 22255482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018804.1", "url": "https://www.ensembl.org/id/ENSGALT00010018804.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010354.1", "url": "https://www.ensembl.org/id/ENSGALP00010010354.1" } ] } }, { "isoform_ac": "A0A8V0XWG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWG6/entry", "sequence": { "sequence": "MFMWWSAVLLLGWILFGADGWPAKEGYDFMPYQPLIRLRHKQEKNQESSRSKGYMDQDGHFKSCENKYCGLGRHCVMNGESGQAECVCMERCKPHYKPVCGSDGEFYENHCEVHRAACLKKQKVAIVHNEDCFFKGDKCKPTEYSKVKNMLLDLQNQRYAAQSKNRNVGEKMALRKLLVDQMFHYFDSDSNGLVDTNELSQVIKRDELGKDLSDCSLFDLLKYDDYNSDKHLGLEEFYRAFQIVQLSLPDDQKLSTTAATVGQSAVLSCAIQGALRPPIIWRRNNVILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYADGYDKLYQTHILEVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTRLGIGNMFYVFYEDGIKVIQPVECEFQRHIKPSEKLLGFQDEVCPKTDGDSVQRCVWATAVNVKDKFIYVTQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVQSWGNMEKNSPTLQVITQASGSISHHTIHTQPVGKQFDRVDDFFIPATTLIITHIRFGFILHKDEPVLQKIDLETMSYIKTISLKDYNCIPQSLAYTHLGGFFFIYCKPDTTGAVLPQLIVDSVTDSVIGYNGDVTGRPHVSPDGHYLVSIDDAKGLMRIQTITMRGEILDAFDIHTNLHISDVAFQPSFTEAHQYNIYCSSSTQTDVLFVELSSGKVKMVKSLKEPVRAGEWPWNSKNRLIKDSGLFGQYLMTPSKESLFILDGRLNKLNCEITEVERGNTVIWVGEA", "length": 837, "header": "tr|A0A8V0XWG6-1|A0A1D5PJN7_CHICK Computationally mapped isoform of Follistatin-related protein 5 OS=Gallus gallus OX=9031 GN=FSTL5 PE=4 SV=1 CANONICAL=A0A1D5PJN7-1" }, "locus": { "chromosome": "4", "start_pos": 22495103, "end_pos": 22255482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018802.1", "url": "https://www.ensembl.org/id/ENSGALT00010018802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010352.1", "url": "https://www.ensembl.org/id/ENSGALP00010010352.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428726", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK67-1", "protein_name": "Follistatin-related protein 5", "gene_name": "Fstl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKCWSAVLILGFIFLASEGRPTKESGYGLKYYQPLTRLRHKQEKSQESSRIKEFLIHDGPFGSCENKYCGLGRHCVISRETRHAECTCMDLCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDNCMTTEYSKMKSMLLDLQNQKYITQENENPNSDDISRKKTLVDQMFKYFDADSNGLVDINELTQVIKQEELNKDLSDCTLYDLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQRVSITAATVGQSAVLSCAVVGTLRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYEDVHQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYDDGVKVIQPTECEFQRHIKPSEKLLGFQDEVCPKDEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTPTLIITHMRFGFILHKDESALHKIDLETMSYIKTISLKDSKCIPLSLAYSHLGGYYFISCKPDITGAIPPQLVVDSVTDSIIGSNSDVTGTPYVSPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSQQTDVLFVELSTGKVKMIKSLKEPLKTEDWPWSPKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 847 }, "evidence": [ { "id": "A0A1D5PJN7", "url": "https://omabrowser.org/oma/group/A0A1D5PJN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A480ZJN6-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKCWSAVLFLGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKQEKSQESSRVKGFLIQNGPLGSCENKYCGLGRHCVLNRETGQAECACVDLCSQHYKPVCGSDGGFYENHCEVHRAACLKKRKITIVHNEDCFFQGDNCKATEYSKMKSMLLDLQNQKYITHNNENPNGDDIFRKKLLVDELFKYFDADSNGLVDINELTQVIKQEELDKDLSGCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSITAATVGQSAVLSCAVQGALRPPIIWKRNNIILNNLELEDINDFGDDGSLYITKVTTTHMGNYTCYADGYEHIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNDAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKTEGDEVQRCVWASAVNVKDKFIYAAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMAKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPATTLLITHMRFGFILHKDEAALQKIDLETMSYIKTIHLKDYKCVPQSLAYTHLGGYYFIGCKPDSTGATPPQLLVDSVTDSVIGFNSDVTGTPYVSPDGHYLVSINDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQSSFTEAHQYNIYGSSSTQTDVLFAELASGKVKMIKSLKEPLKAEEWPWSQKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGDA", "length": 847 }, "evidence": [ { "id": "A0A1D5PJN7", "url": "https://omabrowser.org/oma/group/A0A1D5PJN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N1L7-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKCWSAVLILGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKQEKSQERSRIKGILIQDGSLGSCENKYCGLGRHCVLSRETGQAECACMDHCNRHYKPVCGSDGEFYENHCEVHRAACLKKHKITIVHNEDCFFKGDNCKAIEYSKMKSMLLDLQNQKYITQDNENPNGDDVFRKKLLVDQMFKYFDADSNGLVDINELIQVIKQEELGKDLSDCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSVTAATVGQSTVLSCAIQGALRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYAEGYENIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLSWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEIQRCVWASAVNVKDKFIYVAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLLITHIRFGFILHKDEAALQKIDLETMSYIKTINLKDYQCIPQSLAYTHLGGYYFIGCKPDSTGAAPPQLLVDGVTDSVIGFNSDVTGTPYVSPDGHYLVTISDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELASGKVKMIKSLKEPLKAEEWPWNLKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGEA", "length": 847 }, "evidence": [ { "id": "A0A1D5PJN7", "url": "https://omabrowser.org/oma/group/A0A1D5PJN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BFR2-1", "protein_name": "Follistatin-related protein 5", "gene_name": "Fstl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRCWSAILILGFIFLASEGRPTKESGYGLKSYQPLTRLRHKQEKSQESSRIKEFLIHDGPFGSCENKYCGLGRHCVINRETRHAECACMDLCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFEGDNCMAIEYSKMKSMLLDLQNQKYITQENENPNSDDISRKKPLVDQMFKYFDADSNGLVDINELTQVIKQEELNKDLSDCTLYDLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQRVSITAATVGQSAVLSCAIVGTLRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYENVRQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPTECEFQRHIKPSEKLLGYQDEVCPKAEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTPTLIITHMRFGFILHKDESALHKIDLETMSYIKTINLKDSRCIPLSLAYTHLGGYYFISCKADITGATPPQLVVDSVTDSIIGFNSDVTGTPYVSPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSQQTDVLFVELSSGKVKMIKSLKEPLKTEDWPWSQKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 847 }, "evidence": [ { "id": "A0A1D5PJN7", "url": "https://omabrowser.org/oma/group/A0A1D5PJN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N475-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKCWSVVLVLGFIFLESEGRPTKEGGYGLKSYQPLMRLRHKQEKNQESSRVKGFMIQDGPFGSCENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKCKTTEYSKMKNMLLDLQNQKYIMQENENPNGDDISRKKLLVDQMFKYFDADSNGLVDINELTQVIKQEELGKDLFDCTLYVLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQKLSITAATVGQSAVLSCAIQGTLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHVGNYTCYADGYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEVQRCVWASAVNVKDKFIYVAQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTLEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLIITHMRFGFILHKDEAALQKIDLETMSYIKTINLKDYKCVPQSLAYTHLGGYYFIGCKPDSTGAVSPQVMVDGVTDSVIGFNSDVTGTPYVSPDGHYLVSINDVKGLVRVQYITIRGEIQEAFDIYTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELSSGKVKMIKSLKEPLKAEEWPWNRKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGDA", "length": 847 }, "evidence": [ { "id": "A0A1D5PJN7", "url": "https://omabrowser.org/oma/group/A0A1D5PJN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 846, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJN7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PJQ6-1", "uniprot_ac": "A0A1D5PJQ6", "uniprot_id": "A0A1D5PJQ6_CHICK", "mass": { "chemical_mass": 46112.0, "monoisotopic_mass": 46112.0 }, "refseq": { "ac": "XP_015155045", "name": "WAS/WASL-interacting protein family member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155045" }, "gene_names": [ { "name": "WIPF2", "type": "recommended", "evidence": [ { "id": "A0A1D5PJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6" } ] }, { "name": "WIPF2", "type": "synonym", "evidence": [ { "id": "XP_015155045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155045" } ] } ], "protein_names": [ { "name": "WAS/WASL interacting protein family member 2", "type": "synonym", "evidence": [ { "id": "A0A1D5PJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6/entry#names_and_taxonomy" } ] }, { "name": "WAS/WASL-interacting protein family member 2", "type": "synonym", "evidence": [ { "id": "XP_015155045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155045" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015155045.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WIPF2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6", "locus": { "chromosome": "27", "start_pos": 4389611, "end_pos": 4377255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024541", "url": "https://www.ensembl.org/id/ENSGALG00010024541" } ] } } ], "crossref": [ { "id": "A0A1D5PJQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037633", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771898", "url": "https://www.ncbi.nlm.nih.gov/gene/771898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771898", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWQHNAT", "url": "https://omabrowser.org/oma/group/QWQHNAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PJQ6", "url": "https://www.orthodb.org/?gene=A0A1D5PJQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0B6", "url": "https://www.orthodb.org/?gene=A0A8V1A0B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PJQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIPPPPPPPPGPPPPPTFSQANTEPPKLSREEQRGRGALLQDICKGTKLKKVTQINDRSAPILEKPKGGSGSSYGSSSAAIQPKGGLFQGGVPKLRPVGAKDSSDSSGKQTLQVPGSRAAAPRPPVPASNSRPQDDSDNSRASPPELPRTQRPSLPDLSRPGTAGGTGMKHSSSAPPPPPPGRRATAPPAPPPAHGPKVSSYNREKPLPPTPGQRAPAGRDGPPAPPPVKPPPSPVSIRTGSGAQSQSLAPPPPPYRQPPSVPNGPSSPITESAPELPQRHNSLHRKTPGPLRGLAPPPPASASPSLQSSRPPPPARDPPSRGAAPPPPPPMLRNGGRDAPPPPPPYRLHGSTEPPSRGKPPPPPTRTPAGPPPPPPPVRNGHRDSIATVRAFLDDFESKYSFHPVEDFPAPEEYKYFQRIYPSKTNRATRGAPPLPPIPR", "length": 442, "header": "tr|A0A1D5PJQ6-1|A0A1D5PJQ6_CHICK Isoform 1 of WAS/WASL interacting protein family member 2 OS=Gallus gallus OX=9031 GN=WIPF2 PE=1 SV=2 CANONICAL=A0A1D5PJQ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6/entry", "sequence": { "sequence": "MPIPPPPPPPPGPPPPPTFSQANTEPPKLSREEQRGRGALLQDICKGTKLKKVTQINDRSAPILEKPKGGSGSSYGSSSAAIQPKGGLFQGGVPKLRPVGAKDSSDSSGKQTLQVPGSRAAAPRPPVPASNSRPQDDSDNSRASPPELPRTQRPSLPDLSRPGTAGGTGMKHSSSAPPPPPPGRRATAPPAPPPAHGPKVSSYNREKPLPPTPGQRAPAGRDGPPAPPPVKPPPSPVSIRTGSGAQSQSLAPPPPPYRQPPSVPNGPSSPITESAPELPQRHNSLHRKTPGPLRGLAPPPPASASPSLQSSRPPPPARDPPSRGAAPPPPPPMLRNGGRDAPPPPPPYRLHGSTEPPSRGKPPPPPTRTPAGPPPPPPPVRNGHRDSIATVRAFLDDFESKYSFHPVEDFPAPEEYKYFQRIYPSKTNRATRGAPPLPPIPR", "length": 442, "header": "tr|A0A1D5PJQ6-1|A0A1D5PJQ6_CHICK Isoform 1 of WAS/WASL interacting protein family member 2 OS=Gallus gallus OX=9031 GN=WIPF2 PE=1 SV=2 CANONICAL=A0A1D5PJQ6-1" }, "locus": { "chromosome": "27", "start_pos": 4388561, "end_pos": 4384533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059865.1", "url": "https://www.ensembl.org/id/ENSGALT00010059865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036625.1", "url": "https://www.ensembl.org/id/ENSGALP00010036625.1" } ] } }, { "isoform_ac": "A0A8V1A0B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B6/entry", "sequence": { "sequence": "MSLSPLQGRGVLPRVPLCHCADADLALLAAPPPPPPMLRNGGRDAPPPPPPYRLHGSTEPPSRGKPPPPPTRTPAGPPPPPPPVRNGHRDSIATVRAFLDDFESKYSFHPVEDFPAPEEYKYFQRIYPSKTNRATRGAPPLPPIPRNLHEKLRAPSALPGQADAPSPRSPQTHTAPFPAAPRWTPRCRHGQGRGQAVRCWGWTEAGAVRGGAAWAQSRGGQQPGCGGCGGCGMGPAERSAPLCERRFHAGAAGSGTVPPRWVRGGGVQRRGTPRAPKGASAEGRGLSAGGSEAGGSGGCAPFCLTRTAGSGLYAQRGGSH", "length": 320, "header": "tr|A0A8V1A0B6-1|A0A1D5PJQ6_CHICK Computationally mapped isoform of WAS/WASL interacting protein family member 2 OS=Gallus gallus OX=9031 GN=WIPF2 PE=1 SV=1 CANONICAL=A0A1D5PJQ6-1" }, "locus": { "chromosome": "27", "start_pos": 4389178, "end_pos": 4387360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059863.1", "url": "https://www.ensembl.org/id/ENSGALT00010059863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036623.1", "url": "https://www.ensembl.org/id/ENSGALP00010036623.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771898", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M748-1", "protein_name": "WAS/WASL-interacting protein family member 2 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"MPIPPPPPPPPGPPPPPTFNQANTELPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILEKPKGSSGGYGPGAAALQPKGGLFQGGVPKLRPVGAKDGSENLAGKPALQVPSSRAAAPRPPVSTASGRPQDDTDSNRASLPELPRTQRPSLPDLSRPHATSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSNKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLQSNRPPPPARDPPSRGAAPPPPPPMIRNGARDAPPPPPPYRMHGSEPLSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRVYPSKTNRAARGAPPLPPILR", "length": 440 }, "evidence": [ { "id": "A0A1D5PJQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PEV3-1", "protein_name": "WAS/WASL-interacting protein family member 2", "gene_name": "Wipf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPIPPPPPPPPGPPPPPTFNQANTEQPKLSRDEQRNRGALLQDICKGTKLKKVTNVNDRSAPVIEKPRGSSGGYGPGAAALQPKGGLFQGGVPKLRPVGAKDASEAPAGKPALQVPSSRAAAPRPPGSAASGRPHDDTDSNRASLPELPRMQRPSLPDLSRPNTASGTGMKHSSSAPPPPPPGRRANAPPTPLPLHSNKAQAYNREKPLPPTPGQRLHPGREGHPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSATPSLLSNRPPPPAREPPSRGAAPPPPPPMIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHLQRVYPSKTNRAARGAPPLPPILR", "length": 440 }, "evidence": [ { "id": "A0A1D5PJQ6", "url": "https://omabrowser.org/oma/group/A0A1D5PJQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJQ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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{ "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", 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"Protein Classification" ] }, { "id": "A0A1D5PJT2", "url": "https://www.orthodb.org/?gene=A0A1D5PJT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20516", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20516", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20516:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20516:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PJT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PJT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVSLSVLSLLVALVGASSFVFLVVAIATDFWYIIDASRLETAANGTAALSSHSGLWRTCRLRSKCYPLINPFWYENANITDSHRQLLYMHGTFVILMPLSLILMIFGGMTGFISILARAYLLLLMTGLLFLFGALVTLTGIGVYIAYSAAAFEEAVCLLRSKDVLVEIDIRFGWSLALVWISFVAEVITGAAFLLAARVVGLKQQREQEL", "length": 211, "header": "tr|A0A1D5PJT2-1|A0A1D5PJT2_CHICK Isoform 1 of Transmembrane protein 114 OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A1D5PJT2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJT2/entry", "sequence": { "sequence": "MRVSLSVLSLLVALVGASSFVFLVVAIATDFWYIIDASRLETAANGTAALSSHSGLWRTCRLRSKCYPLINPFWYENANITDSHRQLLYMHGTFVILMPLSLILMIFGGMTGFISILARAYLLLLMTGLLFLFGALVTLTGIGVYIAYSAAAFEEAVCLLRSKDVLVEIDIRFGWSLALVWISFVAEVITGAAFLLAARVVGLKQQREQEL", "length": 211, "header": "tr|A0A1D5PJT2-1|A0A1D5PJT2_CHICK Isoform 1 of Transmembrane protein 114 OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A1D5PJT2-1" }, "locus": { "chromosome": "14", "start_pos": 10146656, "end_pos": 10136155, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041906.1", "url": "https://www.ensembl.org/id/ENSGALT00010041906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024515.1", "url": "https://www.ensembl.org/id/ENSGALP00010024515.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJT2" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PJT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PJT2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 211, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PJT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PJT2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 79, 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PK05-1", "uniprot_ac": "A0A1D5PK05", "uniprot_id": "A0A1D5PK05_CHICK", "mass": { "chemical_mass": 26659.0, "monoisotopic_mass": 26659.0 }, "refseq": { "ac": "XP_015137483", "name": "complement C1q-like protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137483" }, "gene_names": [ { "name": "C1QL3", "type": "recommended", "evidence": [ { "id": "A0A1D5PK05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ] }, { "name": "C1QL3", "type": "synonym", "evidence": [ { "id": "XP_015137483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137483" } ] } ], "protein_names": [ { "name": "Complement C1q like 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PK05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05/entry#names_and_taxonomy" } ] }, { "name": "complement C1q-like protein 3", "type": "synonym", "evidence": [ { "id": "XP_015137483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137483" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015137483.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137483" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QL3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05", "locus": { "chromosome": "2", "start_pos": 20032577, "end_pos": 20028402, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004722", "url": "https://www.ensembl.org/id/ENSGALG00010004722" } ] } } ], "crossref": [ { "id": "A0A1D5PK05", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032554", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032554", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771966", "url": "https://www.ncbi.nlm.nih.gov/gene/771966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771966", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771966", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYEMLKF", "url": "https://omabrowser.org/oma/group/GYEMLKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PK05", "url": "https://www.orthodb.org/?gene=A0A1D5PK05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22923:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22923:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLLVVLIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGDAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255, "header": "tr|A0A1D5PK05-1|A0A1D5PK05_CHICK Isoform 1 of Complement C1q like 3 OS=Gallus gallus OX=9031 GN=C1QL3 PE=4 SV=2 CANONICAL=A0A1D5PK05-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK05-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05/entry", "sequence": { "sequence": "MVLLLVVLIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGDAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255, "header": "tr|A0A1D5PK05-1|A0A1D5PK05_CHICK Isoform 1 of Complement C1q like 3 OS=Gallus gallus OX=9031 GN=C1QL3 PE=4 SV=2 CANONICAL=A0A1D5PK05-1" }, "locus": { "chromosome": "2", "start_pos": 20032574, "end_pos": 20028402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010948.1", "url": "https://www.ensembl.org/id/ENSGALT00010010948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006252.1", "url": "https://www.ensembl.org/id/ENSGALP00010006252.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771966", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771966", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3T5-1", "protein_name": "Complement C1q like 3", "gene_name": "C1ql3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255 }, "evidence": [ { "id": "A0A1D5PK05", "url": "https://omabrowser.org/oma/group/A0A1D5PK05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BM30-1", "protein_name": "Complement C1q like 3", "gene_name": "C1QL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255 }, "evidence": [ { "id": "A0A1D5PK05", "url": "https://omabrowser.org/oma/group/A0A1D5PK05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F2Z5D5-1", "protein_name": "Complement C1q like 3", "gene_name": "C1QL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255 }, "evidence": [ { "id": "A0A1D5PK05", "url": "https://omabrowser.org/oma/group/A0A1D5PK05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VWW1-1", "protein_name": "Complement C1q-like protein 3", "gene_name": "C1QL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255 }, "evidence": [ { "id": "A0A1D5PK05", "url": "https://omabrowser.org/oma/group/A0A1D5PK05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESN4-1", "protein_name": "Complement C1q-like protein 3", "gene_name": "C1ql3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPVGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD", "length": 255 }, "evidence": [ { "id": "A0A1D5PK05", "url": "https://omabrowser.org/oma/group/A0A1D5PK05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "postsynaptic density assembly", "id": "GO:0097107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097107", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "maintenance of synapse structure", "id": "GO:0099558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099558", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "trans-synaptic signaling, modulating synaptic transmission", "id": "GO:0099550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099550", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PK05-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 255, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PK05-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK05" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PK63-1", "uniprot_ac": "A0A1D5PK63", "uniprot_id": "A0A1D5PK63_CHICK", "mass": { "chemical_mass": 18931.0, "monoisotopic_mass": 18931.0 }, "refseq": { "ac": "NP_001026704", "name": "sorting nexin-12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026704" }, "gene_names": [ { "name": "SNX12", "type": "recommended", "evidence": [ { "id": "A0A1D5PK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ] }, { "name": "SNX12", "type": "synonym", "evidence": [ { "id": "NP_001026704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026704" } ] } ], "protein_names": [ { "name": "Sorting nexin 12", "type": "synonym", "evidence": [ { "id": "A0A1D5PK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-12", "type": "synonym", "evidence": [ { "id": "NP_001026704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026704" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721054.1, SRR13267651.4616.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_001026704.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026704" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX12", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63", "locus": { "chromosome": "4", "start_pos": 2379208, "end_pos": 2373171, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018459", "url": "https://www.ensembl.org/id/ENSGALG00010018459" } ] } } ], "crossref": [ { "id": "A0A1D5PK63", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005659", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005659", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428704", "url": "https://www.ncbi.nlm.nih.gov/gene/428704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428704", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMYTDYE", "url": "https://omabrowser.org/oma/group/NMYTDYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PK63", "url": "https://www.orthodb.org/?gene=A0A1D5PK63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6M7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7L2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45963:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45963:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK63-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAAVADTRRLNAKPQDLTDAYGPPSNFLEIDIFNPQTVGMGRARYTSYELRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEETIDRNYVPGKVRQ", "length": 162, "header": "tr|A0A1D5PK63-1|A0A1D5PK63_CHICK Isoform 1 of Sorting nexin 12 OS=Gallus gallus OX=9031 GN=SNX12 PE=1 SV=1 CANONICAL=A0A1D5PK63-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK63-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63/entry", "sequence": { "sequence": "MSEAAVADTRRLNAKPQDLTDAYGPPSNFLEIDIFNPQTVGMGRARYTSYELRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEETIDRNYVPGKVRQ", "length": 162, "header": "tr|A0A1D5PK63-1|A0A1D5PK63_CHICK Isoform 1 of Sorting nexin 12 OS=Gallus gallus OX=9031 GN=SNX12 PE=1 SV=1 CANONICAL=A0A1D5PK63-1" }, "locus": { "chromosome": "4", "start_pos": 2377652, "end_pos": 2375174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044640.1", "url": "https://www.ensembl.org/id/ENSGALT00010044640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026580.1", "url": "https://www.ensembl.org/id/ENSGALP00010026580.1" } ] } }, { "isoform_ac": "A0A8V0Z6M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M7/entry", "sequence": { "sequence": "NCYLHGAPRSGAAKSRGLELKNPPAAPPWPLRQLCSFQHSCEDARNAHRAPTRSGTAAGGSSPLPDTAPHRGGPPGPRSAEPHGARPRYRHGRRGAQRDEERQQTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEETIDRNYVPGKVRQ", "length": 211, "header": "tr|A0A8V0Z6M7-1|A0A8V0Z6M7_CHICK Computationally mapped isoform of Sorting nexin 12 OS=Gallus gallus OX=9031 GN=SNX12 PE=1 SV=1 CANONICAL=A0A1D5PK63-1" }, "locus": { "chromosome": "4", "start_pos": 2377652, "end_pos": 2373561, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044653.1", "url": "https://www.ensembl.org/id/ENSGALT00010044653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026592.1", "url": "https://www.ensembl.org/id/ENSGALP00010026592.1" } ] } }, { "isoform_ac": "A0A8V0Z7L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L2/entry", "sequence": { "sequence": "MSEAAVADTRRLNAKPQDLTDAYGPPSNFLEIDIFNPQTVGMGRARYTSYELRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKMSAAYICSCKRRLLIGITSQGKCASRSTWHCLPPFHPPSCKNDIYFYTKSVFSEPAFPLLNLPVCSVFSSFVTGSSLFFWAVVLA", "length": 214, "header": "tr|A0A8V0Z7L2-1|A0A8V0Z7L2_CHICK Computationally mapped isoform of Sorting nexin 12 OS=Gallus gallus OX=9031 GN=SNX12 PE=1 SV=1 CANONICAL=A0A1D5PK63-1" }, "locus": { "chromosome": "4", "start_pos": 2377833, "end_pos": 2375174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044646.1", "url": "https://www.ensembl.org/id/ENSGALT00010044646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026586.1", "url": "https://www.ensembl.org/id/ENSGALP00010026586.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428704", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A719-1", "protein_name": "Sorting nexin 12", "gene_name": "Snx12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRARVRVVAGCGLAGYFASGRGRARSCLRPLSPTPFAGTGLFFGKMSDTAVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVLGEKDC", "length": 211 }, "evidence": [ { "id": "A0A1D5PK63", "url": "https://omabrowser.org/oma/group/A0A1D5PK63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08826-1", "protein_name": "Sorting nexin-3", "gene_name": "SNX3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSNRFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAEKFVG", "length": 162 }, "evidence": [ { "id": "A0A1D5PK63", "url": "https://omabrowser.org/oma/group/A0A1D5PK63/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9UMY4-2", "protein_name": "Sorting nexin-12", "gene_name": "SNX12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDTAVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVRQ", "length": 162 }, "evidence": [ { "id": "A0A1D5PK63", "url": "https://omabrowser.org/oma/group/A0A1D5PK63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VG51-1", "protein_name": "Sorting nexin-3", "gene_name": "Snx3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVESDGTADATRRLNVKKQTLDDAYAVPANFLEIDVVNPLTTMAAGKKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERDSKIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQNERCLHMFLQENVIDKNYVPGKIRNT", "length": 167 }, "evidence": [ { "id": "A0A1D5PK63", "url": "https://omabrowser.org/oma/group/A0A1D5PK63/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "regulation of protein transport", "id": "GO:0051223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051223", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "regulation of protein metabolic process", "id": "GO:0051246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051246", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "negative regulation of early endosome to late endosome transport", "id": "GO:2000642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000642", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "negative regulation of protein processing", "id": "GO:0010955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010955", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "late endosome to Golgi transport", "id": "GO:0034499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034499", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "negative regulation of protein transport", "id": "GO:0051224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051224", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK63", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PK72-1", "uniprot_ac": "A0A1D5PK72", "uniprot_id": "A0A1D5PK72_CHICK", "mass": { "chemical_mass": 74879.0, "monoisotopic_mass": 74879.0 }, "refseq": { "ac": "NP_001026054", "name": "rho GTPase-activating protein 25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026054" }, "gene_names": [ { "name": "ARHGAP25", "type": "recommended", "evidence": [ { "id": "A0A1D5PK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ] }, { "name": "ARHGAP25", "type": "synonym", "evidence": [ { "id": "NP_001026054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026054" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 24", "type": "recommended", "evidence": [ { "id": "A0A1D5PK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 24", "type": "synonym", "evidence": [ { "id": "A0A1D5PK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 25", "type": "synonym", "evidence": [ { "id": "NP_001026054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026054" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720581.1, ERR2365565.56455.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000331.1. On Nov 20, 2021 this sequence version replaced NP_001026054.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026054" } ] }, { "annotation": "Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72#function" }, { "database": "UniProtKB", "id": "ARBA00058502", "url": "https://www.uniprot.org/uniprotkb/ARBA00058502#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP25", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72", "locus": { "chromosome": "22", "start_pos": 346725, "end_pos": 363538, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020323", "url": "https://www.ensembl.org/id/ENSGALG00010020323" } ] } } ], "crossref": [ { "id": "A0A1D5PK72", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035194", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035194", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419516", "url": "https://www.ncbi.nlm.nih.gov/gene/419516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419516", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419516", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRASTYD", "url": "https://omabrowser.org/oma/group/HRASTYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PK72", "url": "https://www.orthodb.org/?gene=A0A1D5PK72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK89", "url": "https://www.orthodb.org/?gene=A0A8V0ZK89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKLPRNWDFNLKMDAAKIARSRSVMSGEAVTTRPGSPSSMERPLKLGWLKKQRSIVKNWQQRYFVLRGQQLYYYKDEDDTKPQGCLSLQGSTIKEVSGNPEEGGKFIFEIIPGVSGDQNRAGQDTCVLMANSQSDMEEWVKSIRRVLGSTSGAVFGQCLAETMAYEQKFGQHQVPILVQKCAEFIREHGVNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRELPEPVVPWIQYEDFLLCGQTLDMDQKKGHQDLLKQLSLLPRDNYNLLSYICRFLYEVQLNSAVNKMSVDNLATVIGVNLIRPKIEDPATIMRGTLPIQKVMTVMISNHADLFPPSKDVLPSPTAQQNDKKTPILRSSVGWDSAEDSTLPRAESSVQRQMKDHPSASRAPGLAVSSRAPSEDTGLQPSKDTVGMWKMQARKRTQTLPNRKSFLTAASPGEKGSSDRNDIFNSDFWKGSTQSNPHSVLTEGHKRTLSHDLFKLLDLHRASAYDNVPTSHLESSSSSPSPASSCSDKEFQPCPSPCHHPQDPTSPASSPSEVFQPASESKESLQSMVLKLQREMDEQKETYEEQIKSLEKENYDVWAKVVRLNQDIEREKKKSEELELKLKNMERLQEDLEKKNKMLEEEIKTIAKSRSKSDAKTN", "length": 664, "header": "tr|A0A1D5PK72-1|A0A1D5PK72_CHICK Isoform 1 of Rho GTPase-activating protein 24 OS=Gallus gallus OX=9031 GN=ARHGAP25 PE=1 SV=1 CANONICAL=A0A1D5PK72-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72/entry", "sequence": { "sequence": "MSLKLPRNWDFNLKMDAAKIARSRSVMSGEAVTTRPGSPSSMERPLKLGWLKKQRSIVKNWQQRYFVLRGQQLYYYKDEDDTKPQGCLSLQGSTIKEVSGNPEEGGKFIFEIIPGVSGDQNRAGQDTCVLMANSQSDMEEWVKSIRRVLGSTSGAVFGQCLAETMAYEQKFGQHQVPILVQKCAEFIREHGVNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRELPEPVVPWIQYEDFLLCGQTLDMDQKKGHQDLLKQLSLLPRDNYNLLSYICRFLYEVQLNSAVNKMSVDNLATVIGVNLIRPKIEDPATIMRGTLPIQKVMTVMISNHADLFPPSKDVLPSPTAQQNDKKTPILRSSVGWDSAEDSTLPRAESSVQRQMKDHPSASRAPGLAVSSRAPSEDTGLQPSKDTVGMWKMQARKRTQTLPNRKSFLTAASPGEKGSSDRNDIFNSDFWKGSTQSNPHSVLTEGHKRTLSHDLFKLLDLHRASAYDNVPTSHLESSSSSPSPASSCSDKEFQPCPSPCHHPQDPTSPASSPSEVFQPASESKESLQSMVLKLQREMDEQKETYEEQIKSLEKENYDVWAKVVRLNQDIEREKKKSEELELKLKNMERLQEDLEKKNKMLEEEIKTIAKSRSKSDAKTN", "length": 664, "header": "tr|A0A1D5PK72-1|A0A1D5PK72_CHICK Isoform 1 of Rho GTPase-activating protein 24 OS=Gallus gallus OX=9031 GN=ARHGAP25 PE=1 SV=1 CANONICAL=A0A1D5PK72-1" }, "locus": { "chromosome": "22", "start_pos": 363245, "end_pos": 348268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049075.1", "url": "https://www.ensembl.org/id/ENSGALT00010049075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029018.1", "url": "https://www.ensembl.org/id/ENSGALP00010029018.1" } ] } }, { "isoform_ac": "A0A8V0ZDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDT5/entry", "sequence": { "sequence": "MSGEAVTTRPGSPSSMERPLKLGWLKKQRSIVKNWQQRYFVLRGQQLYYYKDEDDTKPQGSTIKEVSGNPEEGGKFIFEIIPGVSGDQNRAGQDTCVLMANSQSDMEEWVKSIRRVLGSTSGAVFGQCLAETMAYEQKFGQHQVPILVQKCAEFIREHGVNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRELPEPVVPWIQYEDFLLCGQTLDMDQKKGHQDLLKQLSLLPRDNYNLLSYICRFLYEVQLNSAVNKMSVDNLATVIGVNLIRPKIEDPATIMRGTLPIQKVMTVMISNHADLFPPSKDVLPSPTAQQNDKKTPILRSSVGWDSAEDSTLPRAESSVQRQMKDHPSASRAPGLAVSSRAPSEDTGLQPSKDTVGMWKMQARKRTQTLPNRKSFLTAASPGEKGSSDRNDIFNSDFWKGSTQSNPHSVLTEGHKRTLSHDLFKLLDLHRASAYDNVPTSHLESSSSSPSPASSCSDKEFQPCPSPCHHPQDPTSPASSPSEVFQPASESKESLQSMVLKLQREMDEQKETYEEQIKSLEKENYDVWAKVVRLNQDIEREKKKSEELELKLKNMERLQEDLEKKNKMLEEEIKTIAKSRSKSDAKTN", "length": 632, "header": "tr|A0A8V0ZDT5-1|A0A8V0ZDT5_CHICK Computationally mapped isoform of Rho GTPase activating protein 25 OS=Gallus gallus OX=9031 GN=ARHGAP25 PE=1 SV=1 CANONICAL=A0A1D5PK72-1" }, "locus": { "chromosome": "22", "start_pos": 359282, "end_pos": 348268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049068.1", "url": "https://www.ensembl.org/id/ENSGALT00010049068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029012.1", "url": "https://www.ensembl.org/id/ENSGALP00010029012.1" } ] } }, { "isoform_ac": "A0A8V0ZK89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK89/entry", "sequence": { "sequence": "MSLKLPRNWDFNLKMDAAKIARSRSVMSGEAVTTRPGSPSSMERPLKLGWLKKQRSIVKNWQQRYFVLRGQQLYYYKDEDDTKPQGCLSLQGSTIKEVSGNPEEGGKFIFEIIPAVFGQCLAETMAYEQKFGQHQVPILVQKCAEFIREHGVNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRELPEPVVPWIQYEDFLLCGQTLDMDQKKGHQDLLKQLSLLPRDNYNLLSYICRFLYEVQLNSAVNKMSVDNLATVIGVNLIRPKIEDPATIMRGTLPIQKVMTVMISNHADLFPPSKDVLPSPTAQQNDKKTPILRSSVGWDSAEDSTLPRAESSVQRQMKDHPSASRAPGLAVSSRAPSEDTGLQPSKDTVGMWKMQARKRTQTLPNRKSFLTAASPGEKGSSDRNDIFNSDFWKGSTQSNPHSVLTEGHKRTLSHDLFKLLDLHRASAYDNVPTSHLESSSSSPSPASSCSDKEFQPCPSPCHHPQDPTSPASSPSEVFQPASESKESLQSMVLKLQREMDEQKETYEEQIKSLEKENYDVWAKVVRLNQDIEREKKKSEELELKLKNMERLQEDLEKKNKMLEEEIKTIAKSRSKSDAKTN", "length": 624, "header": "tr|A0A8V0ZK89-1|A0A8V0ZK89_CHICK Computationally mapped isoform of Rho GTPase activating protein 25 OS=Gallus gallus OX=9031 GN=ARHGAP25 PE=1 SV=1 CANONICAL=A0A1D5PK72-1" }, "locus": { "chromosome": "22", "start_pos": 363245, "end_pos": 348268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049072.1", "url": "https://www.ensembl.org/id/ENSGALT00010049072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029015.1", "url": "https://www.ensembl.org/id/ENSGALP00010029015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419516", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5M6-1", "protein_name": "Rho GTPase activating protein 25", "gene_name": "Arhgap25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSLQPGSALQETCVESLGTIKARSRSVMTGEQMAAFHPPTTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLKARQLYYYKDEEDSKPQGCMYLPGSTVKEIATNPEEAGKFVFEVIPASSDQNRTGQDSYVLMASSQVEMEEWVKFLRRVAGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCSEFILEHGVSEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELEKQLSILPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAQKNDAKKAPVPRSSVGWDATEDPPLSRTDSFNNTASSPDATSPTGPQPGDQHQEDSGKAPKENPGDWKMQSRKRTQTLPNRKCFLTSAFQGTTSSKLEIFKNEFWSPSSEAKAGEGHRRTMSQDLRHLSNDQRTSTYDNVPNPPVSQGNPAGELSPPASDSKRDAPVSTDSEMESGSKNSGEEDPDSLQRTVQHLQKEIEAQKQMYEEQIKNLEKENYDVWAKVVRLNEELERERKKFAALEISLRNVERSREDVEKRNRVLEEEVKEFVKSMEKSKTKTDA", "length": 650 }, "evidence": [ { "id": "A0A1D5PK72", "url": "https://omabrowser.org/oma/group/A0A1D5PK72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SPM2-1", "protein_name": "Rho GTPase activating protein 25", "gene_name": "ARHGAP25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLKLPRNWDFSLRGEAGKIARSRSVMTGEQMAAFHPASSPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDVKPQGYMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPNFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLMNADEAKAQQELVKQLSILPRDNYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPKNDPKKPPVARSSVGWDASEDPPISRTDSINNMTSDSDATSPTGQRPNDGCLEDSIKASKEKPGDWKMQSRKRTQTLPNRKCFLTSALQGANSCKTEVIKNEFCSPSSEAKAGEGHRRTMSQGVPQFFDTQRTSTYDNVPVQPGSPGDKADALSPQAYDSKRDAPGSPNSEARPGKKNSGEEELESFQRMLVQELRKEIQTQKQMYEEQIKNLEKENYDVWTKVVRLNEELEKEKKKSAALEISLRNVERSLEDVERRNKALEEEVKEFVRSMKEPKTNA", "length": 647 }, "evidence": [ { "id": "A0A1D5PK72", "url": "https://omabrowser.org/oma/group/A0A1D5PK72/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P42331-1", "protein_name": "Rho GTPase-activating protein 25", "gene_name": "ARHGAP25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA", "length": 645 }, "evidence": [ { "id": "A0A1D5PK72", "url": "https://omabrowser.org/oma/group/A0A1D5PK72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BYW1-1", "protein_name": "Rho GTPase-activating protein 25", "gene_name": "Arhgap25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLKLPRNWDFNLKAEASKIARSRSVMTGEQMAAFHPPTTPNPLERPIKVGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDSKPQGCMYLPGSTVKEIATNPEEAGKFVFEVIPASSDQNRIGQDSYVLMASSQVEMEEWVKFLRRVAGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGVSEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLMNADEAKAQQELVKQLSTLPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPISPPAQKNDAKKAPVPRSSVGWDATEDPPLSRTDSFSNTASSPDATSPTGPLPSDQHQEDSGKAPRENPGDWKMQSRKRTQTLPNRKCFLTSAFQGTTSSKLEIFKNEFWSPSSEAKAGEGHRRTMSQDLRHLSNDQRTSTYDNVPTSPQSQGNPAGALSPPASDSKRDALVSTDSEMEAGSKNSGEDDLDSLQRTVQSLQKEIETQKQVYEEQIKNLEKENYDVWAKVVRLNEELERERKKFAALEISLRNVERSREDVEKRNRVLEEEVKEFVKSMEKPKTKTDP", "length": 648 }, "evidence": [ { "id": "A0A1D5PK72", "url": "https://omabrowser.org/oma/group/A0A1D5PK72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RWQ4-1", "protein_name": "Rho GTPase-activating protein 7", "gene_name": "ROPGAP7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEASLAALERPRGSASNTVFKSGPLFISSKGLGWTSWKKRWFILTRTSLVFFKNDPGTLPQKGGEVNLTLGGIDLNNSGSVVVREDKKLLTVLFPDGRDGRAFTLKAETFEDLYEWKTALEQALAQAPNAALIMGQNGIFRAETNEAIEGREKRPLKSLVVGRPILLALEDIDGSPSFLEKALQFIEKYGTKIEGILRQSADVEEVERRVQEYEQGKTEFTFDEDPHVVGDCIKHVLRELPSSPVSASCCTALLEAYRIESKEARISSLRSAIAETFPEPNRRLLQRILKMMHTISSHSHENRMNPNAVAACMAPLLLRPLLAGECDLEDDFDGGEDNSAQLLAAANAANNAQAIITVLLEDYGSIFDEENIQRCSISTESHIGNSGPDDSSDDDNNMKNGYHNADNEVEPVTDDDNDRALSGKMSESSGCTGSDLYEYKGFVADDSDIESPRDTNGPRCNSNIRTDHLMRNPFVNSTDQQAGEQIGDDPTKYGVNSCLAHVSESYQQSGTGLNVPTHGNTLAAPGLESPSAKSVNKGTPSSVHAKRATFWGRGSARKISTDGSFDSSGEDELAIQRLETTKNELRQRIAKEARGNAILQASLERRKQALHERRLSLEQDVSRLQEQLQAERDLRAALEVGLSMSSGQFSSHGVDSKTRAELEEIALAEADVARLKQKVAELHHQLNQQRQTHFGSFSDARDTHQYLQNHNPQKRFLQQDFDSTLAYVNHERKQRHEENVLGAEWRNSKGAGSFGVGNSRQPSRKQIPESTNTTDSKISEESGKISVDKLSSIDSPSIPSTSRVLDITEYPRLNHPSAAASAALVELTTRLDFFKERRSQLMEQLQNLDLNYGGSSSQDFIHRPSSPPWN", "length": 870 }, "evidence": [ { "id": "A0A1D5PK72", "url": "https://omabrowser.org/oma/group/A0A1D5PK72/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK72", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PK72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 664, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PK72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PK72" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PKK3-1", "uniprot_ac": "A0A1D5PKK3", "uniprot_id": "A0A1D5PKK3_CHICK", "mass": { "chemical_mass": 12159.0, "monoisotopic_mass": 12159.0 }, "refseq": { "ac": "NP_001186402", "name": "large ribosomal subunit protein mL53", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402" }, "gene_names": [ { "name": "MRPL53", "type": "recommended", "evidence": [ { "id": "A0A1D5PKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3" } ] }, { "name": "MRPL53", "type": "synonym", "evidence": [ { "id": "NP_001186402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL53", "type": "recommended", "evidence": [ { "id": "A0A1D5PKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L53, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001186402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402" }, { "id": "A0A1D5PKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein mL53", "type": "synonym", "evidence": [ { "id": "NP_001186402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000616.1, CF250315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Dec 9, 2010 this sequence version replaced XP_418307.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186402", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKK3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL53", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3", "locus": { "chromosome": "2", "start_pos": 120952019, "end_pos": 120948172, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002834", "url": "https://www.ensembl.org/id/ENSGALG00010002834" } ] } } ], "crossref": [ { "id": "A0A1D5PKK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PKK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037867", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420196", "url": "https://www.ncbi.nlm.nih.gov/gene/420196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420196", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKMWERI", "url": "https://omabrowser.org/oma/group/CKMWERI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PKK3", "url": "https://www.orthodb.org/?gene=A0A1D5PKK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33618:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33618:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186402", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186402", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKK3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRIRVVLRPVKSIVVRFCPFESNVESTRKFLQCINHKRIQATNRNCEVSADVRHDGSEPLVDVMFADGERLIMKGANLTTVEMLTALGSRCNAKELKAEQKSKKNP", "length": 108, "header": "tr|A0A1D5PKK3-1|A0A1D5PKK3_CHICK Isoform 1 of Large ribosomal subunit protein mL53 OS=Gallus gallus OX=9031 GN=MRPL53 PE=1 SV=1 CANONICAL=A0A1D5PKK3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3/entry", "sequence": { "sequence": "MASRIRVVLRPVKSIVVRFCPFESNVESTRKFLQCINHKRIQATNRNCEVSADVRHDGSEPLVDVMFADGERLIMKGANLTTVEMLTALGSRCNAKELKAEQKSKKNP", "length": 108, "header": "tr|A0A1D5PKK3-1|A0A1D5PKK3_CHICK Isoform 1 of Large ribosomal subunit protein mL53 OS=Gallus gallus OX=9031 GN=MRPL53 PE=1 SV=1 CANONICAL=A0A1D5PKK3-1" }, "locus": { "chromosome": "2", "start_pos": 120951301, "end_pos": 120948192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006557.1", "url": "https://www.ensembl.org/id/ENSGALT00010006557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004030.1", "url": "https://www.ensembl.org/id/ENSGALP00010004030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420196", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H729-1", "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "Mrpl53", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASALARVGLKPVKLVRVQFCPFEKNVESTRTFLQAVSSEKVRATNLNCSVVADVRHDGSEPCVDVLFGDGYRLIMRSANLTAQEMFTALASHIRARNAAAASAAANADKPGPVNGTRR", "length": 119 }, "evidence": [ { "id": "A0A1D5PKK3", "url": "https://omabrowser.org/oma/group/A0A1D5PKK3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2HJF1-1", "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "MRPL53", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAALARLGLRSVKQVRVQFCPFEKNVESTRTFLQAVSSEKVRSTNLNCSVIADVRHDGSEPCVDVLFGDGHRLIMRGAHLTAQEMLSAFASHIQARGAAASGDKPSASTGR", "length": 112 }, "evidence": [ { "id": "A0A1D5PKK3", "url": "https://omabrowser.org/oma/group/A0A1D5PKK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96EL3-1", "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "MRPL53", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAALARLGLRPVKQVRVQFCPFEKNVESTRTFLQTVSSEKVRSTNLNCSVIADVRHDGSEPCVDVLFGDGHRLIMRGAHLTALEMLTAFASHIRARDAAGSGDKPGADTGR", "length": 112 }, "evidence": [ { "id": "A0A1D5PKK3", "url": "https://omabrowser.org/oma/group/A0A1D5PKK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1H8-1", "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "Mrpl53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALARLGLRPVKLVRVQFCPFEKNVESTRTFLQTVSSEKVRATNLNCSVIADVRHDGSEPCVDVLFGDGYRLIMRGAHLTTQEMLSALASHIRDRNAAAASAPGADKVAPGTSTRR", "length": 118 }, "evidence": [ { "id": "A0A1D5PKK3", "url": "https://omabrowser.org/oma/group/A0A1D5PKK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKK3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PKK3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 108, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PKK3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PKK3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PKQ5-1", "uniprot_ac": "A0A1D5PKQ5", "uniprot_id": "A0A1D5PKQ5_CHICK", "mass": { "chemical_mass": 40081.0, "monoisotopic_mass": 40081.0 }, "refseq": { "ac": "XP_004942096", "name": "activating signal cointegrator 1 complex subunit 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942096" }, "gene_names": [ { "name": "ASCC1", "type": "recommended", "evidence": [ { "id": "A0A1D5PKQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ] }, { "name": "ASCC1", "type": "synonym", "evidence": [ { "id": "XP_004942096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942096" } ] } ], "protein_names": [ { "name": "Activating signal cointegrator 1 complex subunit 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PKQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5/entry#names_and_taxonomy" } ] }, { "name": "activating signal cointegrator 1 complex subunit 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942096" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004942096.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASCC1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5", "locus": { "chromosome": "6", "start_pos": 12209442, "end_pos": 12180195, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021645", "url": "https://www.ensembl.org/id/ENSGALG00010021645" } ] } } ], "crossref": [ { "id": "A0A1D5PKQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PKQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026019", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423709", "url": "https://www.ncbi.nlm.nih.gov/gene/423709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423709", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PKQ5", "url": "https://www.orthodb.org/?gene=A0A1D5PKQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZJE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL12", "url": "https://www.orthodb.org/?gene=A0A8V0ZL12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL74", "url": "https://www.orthodb.org/?gene=A0A8V0ZL74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL86", "url": "https://www.orthodb.org/?gene=A0A8V0ZL86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZRS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRT8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13360:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13360:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PKQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVLRPTLVRIGGRVYRKNIIHEQVQQQEEEENFYTGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 355, "header": "tr|A0A1D5PKQ5-1|A0A1D5PKQ5_CHICK Isoform 1 of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=2 CANONICAL=A0A1D5PKQ5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PKQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5/entry", "sequence": { "sequence": "MDVLRPTLVRIGGRVYRKNIIHEQVQQQEEEENFYTGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 355, "header": "tr|A0A1D5PKQ5-1|A0A1D5PKQ5_CHICK Isoform 1 of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=2 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12183368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052577.1", "url": "https://www.ensembl.org/id/ENSGALT00010052577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031483.1", "url": "https://www.ensembl.org/id/ENSGALP00010031483.1" } ] } }, { "isoform_ac": "A0A8V0ZJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE9/entry", "sequence": { "sequence": "MDVLRPTLVRIGGRVYRKNIIHEQVQQQEEEENFYTGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKVLCCFAAEQENINDWTRQAEC", "length": 338, "header": "tr|A0A8V0ZJE9-1|A0A8V0ZJE9_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12205348, "end_pos": 12183368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052580.1", "url": "https://www.ensembl.org/id/ENSGALT00010052580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031486.1", "url": "https://www.ensembl.org/id/ENSGALP00010031486.1" } ] } }, { "isoform_ac": "A0A8V0ZL12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL12/entry", "sequence": { "sequence": "PGFRSEPLPGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 328, "header": "tr|A0A8V0ZL12-1|A0A8V0ZL12_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12182032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052582.1", "url": "https://www.ensembl.org/id/ENSGALT00010052582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031488.1", "url": "https://www.ensembl.org/id/ENSGALP00010031488.1" } ] } }, { "isoform_ac": "A0A8V0ZL74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL74/entry", "sequence": { "sequence": "MARRPWKSSVMDVLRPTLVRIGGRVYRKNIIHEQVQQQEEEENFYTGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 365, "header": "tr|A0A8V0ZL74-1|A0A8V0ZL74_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12183017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052576.1", "url": "https://www.ensembl.org/id/ENSGALT00010052576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031482.1", "url": "https://www.ensembl.org/id/ENSGALP00010031482.1" } ] } }, { "isoform_ac": "A0A8V0ZL86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL86/entry", "sequence": { "sequence": "MLSCSLSGGSLPCLKHCHRLKTEVTARKVTSSQAIGGREGRSRKAGHGKRHSDWAWPWSFLPPSGFCQPKSERALGSHACGEGGGAEVSQRNHLPASPRLPWARRPWKSSVMDVLRPTLVRIGGRVYRKNIIHEQVQQQEEEENFYTGPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 466, "header": "tr|A0A8V0ZL86-1|A0A8V0ZL86_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12180394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052586.1", "url": "https://www.ensembl.org/id/ENSGALT00010052586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031492.1", "url": "https://www.ensembl.org/id/ENSGALP00010031492.1" } ] } }, { "isoform_ac": "A0A8V0ZRS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS9/entry", "sequence": { "sequence": "CSGIPLRAHLPSNSCLYFCSSPSLEEQCDGCPATHPGQDRWASVQEEHHSRAGPAARGGGELLHRYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 350, "header": "tr|A0A8V0ZRS9-1|A0A8V0ZRS9_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12183283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052574.1", "url": "https://www.ensembl.org/id/ENSGALT00010052574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031480.1", "url": "https://www.ensembl.org/id/ENSGALP00010031480.1" } ] } }, { "isoform_ac": "A0A8V0ZRT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT8/entry", "sequence": { "sequence": "RAASRSPSLEEQCDGCPATHPGQDRWASVQEEHHSRAGPAARGGGELLHRWPSDCADEPCDAFVVEETDKGFQCRVEVPSPLYKYIIGKKGETKKRIETETRTSISIPKPGLEGEIVITGQQRGGVISARTRIDVLLDSFRKKQPFTHFLSFALNQPVVQEKFLQFKEEVLEKCSQDHGVSSSLFQNPAKLHLTLGTLVLLNEQEIQRACDLLQQCKEDFVDQITGGKPLSVEVAGVEYMNDDPAMMDVLYAKVHMKDGSDKLQVIADQLVEKFVASGLMLREWDRVKLHATVMNTLFRKDPSGAEERSSTVSGKSSFKERESFNGRNILKLFENFSFGEVQLDAVLLSQRYSSDASGYYGTAGRLLLH", "length": 369, "header": "tr|A0A8V0ZRT8-1|A0A8V0ZRT8_CHICK Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 1 OS=Gallus gallus OX=9031 GN=ASCC1 PE=4 SV=1 CANONICAL=A0A1D5PKQ5-1" }, "locus": { "chromosome": "6", "start_pos": 12209205, "end_pos": 12182046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052584.1", "url": "https://www.ensembl.org/id/ENSGALT00010052584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031490.1", "url": "https://www.ensembl.org/id/ENSGALP00010031490.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA alkylation repair", "id": "GO:0006307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006307", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PKQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PKQ5" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 124, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PL04-1", "uniprot_ac": "A0A1D5PL04", "uniprot_id": "A0A1D5PL04_CHICK", "mass": { "chemical_mass": 44626.0, "monoisotopic_mass": 44626.0 }, "refseq": { "ac": "XP_004944662", "name": "Krueppel-like factor 15 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944662" }, "gene_names": [ { "name": "KLF15", "type": "recommended", "evidence": [ { "id": "A0A1D5PL04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ] }, { "name": "KLF15", "type": "synonym", "evidence": [ { "id": "XP_004944662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944662" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 15", "type": "recommended", "evidence": [ { "id": "A0A1D5PL04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 15 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004944662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944662" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944662" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF15", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04", "locus": { "chromosome": "12", "start_pos": 10806952, "end_pos": 10833065, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021173", "url": "https://www.ensembl.org/id/ENSGALG00010021173" } ] } } ], "crossref": [ { "id": "A0A1D5PL04", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PL04", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036133", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036133", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427588", "url": "https://www.ncbi.nlm.nih.gov/gene/427588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427588", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427588", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NAAASWW", "url": "https://omabrowser.org/oma/group/NAAASWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PL04", "url": "https://www.orthodb.org/?gene=A0A1D5PL04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB62", "url": "https://www.orthodb.org/?gene=A0A8V0ZB62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB70", "url": "https://www.orthodb.org/?gene=A0A8V0ZB70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGV4", "url": "https://www.orthodb.org/?gene=A0A8V0ZGV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944662", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDHLVPTDESFASTRSSLGYFRDMTAGVRSYQMLPSPLSEDDSDSSSFCSCSSPESQVLSSSYGSTSSAESQDSILDYLLSQASLGNTAASWWDKRRLQPIVKEEYFRLPEFAVDMEDSGPFQPTLEEIEEFLEENMELELKERPKSETKDLRACSQVSVASLQQKDHMLPNATLKESKNEQLSSSTEGGQASNGGVSLENGIPVMLQIQPVQIKQESSTSPSSQGPAQENIKIAQLLVNIQGQTFALVPQIVQSSNLNLPSKFVRIAPVPIAAKPIGPGGMIQGQTGIIMGQKFQKNPAAELIKMHKCSFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRSVRSVN", "length": 403, "header": "tr|A0A1D5PL04-1|A0A1D5PL04_CHICK Isoform 1 of Krueppel-like factor 15 OS=Gallus gallus OX=9031 GN=KLF15 PE=4 SV=3 CANONICAL=A0A1D5PL04-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04/entry", "sequence": { "sequence": "MVDHLVPTDESFASTRSSLGYFRDMTAGVRSYQMLPSPLSEDDSDSSSFCSCSSPESQVLSSSYGSTSSAESQDSILDYLLSQASLGNTAASWWDKRRLQPIVKEEYFRLPEFAVDMEDSGPFQPTLEEIEEFLEENMELELKERPKSETKDLRACSQVSVASLQQKDHMLPNATLKESKNEQLSSSTEGGQASNGGVSLENGIPVMLQIQPVQIKQESSTSPSSQGPAQENIKIAQLLVNIQGQTFALVPQIVQSSNLNLPSKFVRIAPVPIAAKPIGPGGMIQGQTGIIMGQKFQKNPAAELIKMHKCSFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRSVRSVN", "length": 403, "header": "tr|A0A1D5PL04-1|A0A1D5PL04_CHICK Isoform 1 of Krueppel-like factor 15 OS=Gallus gallus OX=9031 GN=KLF15 PE=4 SV=3 CANONICAL=A0A1D5PL04-1" }, "locus": { "chromosome": "12", "start_pos": 10815078, "end_pos": 10808747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051308.1", "url": "https://www.ensembl.org/id/ENSGALT00010051308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030499.1", "url": "https://www.ensembl.org/id/ENSGALP00010030499.1" } ] } }, { "isoform_ac": "A0A8V0ZB62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB62/entry", "sequence": { "sequence": "MDISSQQLHTSGSSRAFCTLQPLCNSRIQPALHGAGRETERIWPREVKAAQKGSHLNLRCVVYAAGIPVGARPGMVDHLVPTDESFASTRSSLGYFRDMTAGVRSYQMLPSPLSEDDSDSSSFCSCSSPESQVLSSSYGSTSSAESQDSILDYLLSQASLGNTAASWWDKRRLQPIVKEEYFRLPEFAVDMEDSGPFQPTLEEIEEFLEENMELELKERPKSETKDLRACSQVSVASLQQKDHMLPNATLKESKNEQLSSSTEGGQASNGGVSLENGIPVMLQIQPVQIKQESSTSPSSQGPAQENIKIAQLLVNIQGQTFALVPQIVQSSNLNLPSKFVRIAPVPIAAKPIGPGGMIQGQTGIIMGQKFQKNPAAELIKMHKCSFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRSVRSVN", "length": 477, "header": "tr|A0A8V0ZB62-1|A0A8V0ZB62_CHICK Computationally mapped isoform of Krueppel-like factor 15 OS=Gallus gallus OX=9031 GN=KLF15 PE=4 SV=1 CANONICAL=A0A1D5PL04-1" }, "locus": { "chromosome": "12", "start_pos": 10821355, "end_pos": 10808747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051317.1", "url": "https://www.ensembl.org/id/ENSGALT00010051317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030507.1", "url": "https://www.ensembl.org/id/ENSGALP00010030507.1" } ] } }, { "isoform_ac": "A0A8V0ZB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB70/entry", "sequence": { "sequence": "MLSLLNDTCSPWVPLVCRKTHFSPQLRCRQMSPEVGALGSHLNLRCVVYAAGIPVGARPGMVDHLVPTDESFASTRSSLGYFRDMTAGVRSYQMLPSPLSEDDSDSSSFCSCSSPESQVLSSSYGSTSSAESQDSILDYLLSQASLGNTAASWWDKRRLQPIVKEEYFRLPEFAVDMEDSGPFQPTLEEIEEFLEENMELELKERPKSETKDLRACSQVSVASLQQKDHMLPNATLKESKNEQLSSSTEGGQASNGGVSLENGIPVMLQIQPVQIKQESSTSPSSQGPAQENIKIAQLLVNIQGQTFALVPQIVQSSNLNLPSKFVRIAPVPIAAKPIGPGGMIQGQTGIIMGQKFQKNPAAELIKMHKCSFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRSVRSVN", "length": 463, "header": "tr|A0A8V0ZB70-1|A0A8V0ZB70_CHICK Computationally mapped isoform of Krueppel-like factor 15 OS=Gallus gallus OX=9031 GN=KLF15 PE=4 SV=1 CANONICAL=A0A1D5PL04-1" }, "locus": { "chromosome": "12", "start_pos": 10831910, "end_pos": 10808747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051321.1", "url": "https://www.ensembl.org/id/ENSGALT00010051321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030512.1", "url": "https://www.ensembl.org/id/ENSGALP00010030512.1" } ] } }, { "isoform_ac": "A0A8V0ZGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV4/entry", "sequence": { "sequence": "MSSSLFWLFERSRGSHLNLRCVVYAAGIPVGARPGMVDHLVPTDESFASTRSSLGYFRDMTAGVRSYQMLPSPLSEDDSDSSSFCSCSSPESQVLSSSYGSTSSAESQDSILDYLLSQASLGNTAASWWDKRRLQPIVKEEYFRLPEFAVDMEDSGPFQPTLEEIEEFLEENMELELKERPKSETKDLRACSQVSVASLQQKDHMLPNATLKESKNEQLSSSTEGGQASNGGVSLENGIPVMLQIQPVQIKQESSTSPSSQGPAQENIKIAQLLVNIQGQTFALVPQIVQSSNLNLPSKFVRIAPVPIAAKPIGPGGMIQGQTGIIMGQKFQKNPAAELIKMHKCSFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRSVRSVN", "length": 438, "header": "tr|A0A8V0ZGV4-1|A0A8V0ZGV4_CHICK Computationally mapped isoform of Krueppel-like factor 15 OS=Gallus gallus OX=9031 GN=KLF15 PE=4 SV=1 CANONICAL=A0A1D5PL04-1" }, "locus": { "chromosome": "12", "start_pos": 10824330, "end_pos": 10808747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051318.1", "url": "https://www.ensembl.org/id/ENSGALT00010051318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030509.1", "url": "https://www.ensembl.org/id/ENSGALP00010030509.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427588", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9UIH9-1", "protein_name": "Krueppel-like factor 15", "gene_name": "KLF15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPCSCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASSGPVAWGPWRRAAAPVKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN", "length": 416 }, "evidence": [ { "id": "A0A1D5PL04", "url": "https://omabrowser.org/oma/group/A0A1D5PL04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL04", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL04" } ], "pmid": "" }, { 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Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. 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"https://www.uniprot.org/uniprotkb/A0A8V0ZZV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGRRAAPRCGWGWGGGWGCCPFLCLLLCCGAAGRPEVYMPAVLEVEIGSTARLECSFSIPGNASFTSVEWFYVNRGHSDRVRLCVITASGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFYPTEHVELRVATNAGIVKEGDDVKLVCDADGNPAPVFSFFRRELGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNYIEGVQVKMEPSSPLHEGDSVRLSCTAHSPVKLDYQWRDARGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDITKPEARKDKNVVEVKSDKLSEEAGLLQGANGEKRSPADQSEKYIDLRN", "length": 626, "header": "tr|A0A1D5PL70-1|A0A1D5PL70_CHICK Isoform 1 of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=2 CANONICAL=A0A1D5PL70-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PL70-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70/entry", "sequence": { "sequence": "MAGGRRAAPRCGWGWGGGWGCCPFLCLLLCCGAAGRPEVYMPAVLEVEIGSTARLECSFSIPGNASFTSVEWFYVNRGHSDRVRLCVITASGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFYPTEHVELRVATNAGIVKEGDDVKLVCDADGNPAPVFSFFRRELGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNYIEGVQVKMEPSSPLHEGDSVRLSCTAHSPVKLDYQWRDARGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDITKPEARKDKNVVEVKSDKLSEEAGLLQGANGEKRSPADQSEKYIDLRN", "length": 626, "header": "tr|A0A1D5PL70-1|A0A1D5PL70_CHICK Isoform 1 of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=2 CANONICAL=A0A1D5PL70-1" }, "locus": { "chromosome": "24", "start_pos": 4274554, "end_pos": 4266896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058841.1", "url": "https://www.ensembl.org/id/ENSGALT00010058841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035806.1", "url": "https://www.ensembl.org/id/ENSGALP00010035806.1" } ] } }, { "isoform_ac": "A0A8V0ZY32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY32/entry", "sequence": { "sequence": "MAGGRRAAPRCGWGWGGGWGCCPFLCLLLCCGAAGRPEVYMPAVLEVEIGSTARLECSFSIPGNASFTSVEWFYVSARPLRSGEAVRHHASGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFYPTEHVELRVATNAGIVKEGDDVKLVCDADGNPAPVFSFFRRELGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNYIEGVQVKMEPSSPLHEGDSVRLSCTAHSPVKLDYQWRDARGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDITKPEARKDKNVVEVKSDKLSEEAGLLQGANGEKRSPADQSEKYIDLRN", "length": 626, "header": "tr|A0A8V0ZY32-1|A0A1D5PL70_CHICK Computationally mapped isoform of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1D5PL70-1" }, "locus": { "chromosome": "24", "start_pos": 4274554, "end_pos": 4266896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058844.1", "url": "https://www.ensembl.org/id/ENSGALT00010058844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035809.1", "url": "https://www.ensembl.org/id/ENSGALP00010035809.1" } ] } }, { "isoform_ac": "A0A8V0ZY37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY37/entry", "sequence": { "sequence": "MAGGRRAAPRCGWGWGGGWGCCPFLCLLLCCGAAGRPEVYMPSAGSGDREHSQAGVQLLHPWECLLHLRRVVLCQPRPLRSGEAVRHHASGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFYPTEHVELRVATNAGIVKEGDDVKLVCDADGNPAPVFSFFRRELGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNYIEGVQVKMEPSSPLHEGDSVRLSCTAHSPVKLDYQWRDARGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDITKPEARKDKNVVEVKSDKLSEEAGLLQGANGEKRSPADQSEKYIDLRN", "length": 625, "header": "tr|A0A8V0ZY37-1|A0A1D5PL70_CHICK Computationally mapped isoform of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1D5PL70-1" }, "locus": { "chromosome": "24", "start_pos": 4274554, "end_pos": 4266896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058849.1", "url": "https://www.ensembl.org/id/ENSGALT00010058849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035814.1", "url": "https://www.ensembl.org/id/ENSGALP00010035814.1" } ] } }, { "isoform_ac": "A0A8V0ZZV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV8/entry", "sequence": { "sequence": "MAGGRRAAPRCGWGWGGGWGCCPFLCLLLCCGAAGRPEVYMPAVLEVEIGSTARLECSFSIPGNASFTSVEWFYVNRGHSDRVRLCVITASGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFYPTEHVELRVATNAGIVKEGDDVKLVCDADGNPAPVFSFFRRELGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNYIEGVQVKMEPSSPLHEGDSVRLSCTAHSPVKLDYQWRDARGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDIARNTSI", "length": 584, "header": "tr|A0A8V0ZZV8-1|A0A1D5PL70_CHICK Computationally mapped isoform of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1D5PL70-1" }, "locus": { "chromosome": "24", "start_pos": 4274546, "end_pos": 4266896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058853.1", "url": "https://www.ensembl.org/id/ENSGALT00010058853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035818.1", "url": "https://www.ensembl.org/id/ENSGALP00010035818.1" } ] } }, { "isoform_ac": "A0A8V1A3E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3E5/entry", "sequence": { "sequence": "METCSPGVSRGPAVLGTWCKGAVPPPGAAGRPEVYMPAVLEVEIGSTARLECSFSIPGNASFTSVEWFYVSQPRGVRIDETEYSERLSVGEDKALSISKVTRQDNARTFICQVGADSQGVGESRTELYTYKIPAPPEITPNSAGIPAQSNDMLKIAQCTSENSFPSPNITWYKNGEPLLQEEDKTKILTTLVRESNGLYTVVSTLFSKVTREDRNSLFHCTVHYWLQGQMRTKDSPRVNVTVFCEARGARGEGVWSLSLGIPCPRMEGLRVVLSLCLQLGDSWQDMTSLADTNDGVLMLHNVSKSSSGLYRCQTLDLDDMTQHEGDVELVVNCKAGGRDTVHPVGGTPSLSPALGFPLQQGRKVAEGNQLLLTNLTFETSSNFSCRVKARSVPGLEQSKQVAVAVKGKPRIVAISAPLYVRQDEVINLTCKAIAFPQPSFHWSVNGTTHEYMENQHMASNLTVRVSHDLLRAGAMCRVSNALGVSEKHIQLLDQKPSESKGIIIVAIIVCILVVAVLGSIIYFLHKKGKISCGRSGKQDITKPEARKDKNVVEVKSDKLSEEAGLLQGANGEKRSPADQVGPSIVCWGQGCAVLSSSQRCSR", "length": 602, "header": "tr|A0A8V1A3E5-1|A0A1D5PL70_CHICK Computationally mapped isoform of Cell surface glycoprotein MUC18 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1D5PL70-1" }, "locus": { "chromosome": "24", "start_pos": 4273946, "end_pos": 4270183, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058825.1", "url": "https://www.ensembl.org/id/ENSGALT00010058825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035790.1", "url": "https://www.ensembl.org/id/ENSGALP00010035790.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": 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"GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" }, { "name": "glomerular filtration", "id": "GO:0003094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" }, { "name": "vascular wound healing", "id": "GO:0061042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061042", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PL70", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PLB4-1", "uniprot_ac": "A0A1D5PLB4", "uniprot_id": "A0A1D5PLB4_CHICK", "mass": { "chemical_mass": 39245.0, "monoisotopic_mass": 39245.0 }, "refseq": {}, "gene_names": [ { "name": "TARP", "type": "recommended", "evidence": [ { "id": "A0A1D5PLB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4" } ] } ], "protein_names": [ { "name": "TCR gamma alternate reading frame protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PLB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { 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"https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLB4", "url": "https://www.orthodb.org/?gene=A0A1D5PLB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW96", "url": "https://www.orthodb.org/?gene=A0A8V0YW96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4C6", "url": "https://www.orthodb.org/?gene=A0A8V0Z4C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PLB4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLALAEAWLHPFPSPWRLHWQQQQEAVLRTPAGSRLAVLAVFSLLLIDGHAQVLLQQRQPSATRERSKTVTIQCHVEGIADFHNAYIHWYRQMPAKAPERLLYVTAVAQVSYDSDSYKNKYTSSKMGNKICTLSVQDIGDDDKGTYYCAYRESHRGYYYKVFGSGTKLIVSDKGSSAPENYEIMQEEHEKQVVYVCLIEKFYPEVIRVKWTDEANKEVTQNVVKGDVWKSPGEDKYSVSTWLSVPLESKNKIYSCTYEHESGGNSLSTQDLFPVPSSERSPQEQDCGTQSGNSTVVNRDHMTHKAAQLVYVVLLLKSSMYYVIVLFFFFKYRTRTAAKPSGKKT", "length": 344, "header": "tr|A0A1D5PLB4-1|A0A1D5PLB4_CHICK Isoform 1 of TCR gamma alternate reading frame protein OS=Gallus gallus OX=9031 GN=TARP PE=4 SV=2 CANONICAL=A0A1D5PLB4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4/entry", "sequence": { "sequence": "MLALAEAWLHPFPSPWRLHWQQQQEAVLRTPAGSRLAVLAVFSLLLIDGHAQVLLQQRQPSATRERSKTVTIQCHVEGIADFHNAYIHWYRQMPAKAPERLLYVTAVAQVSYDSDSYKNKYTSSKMGNKICTLSVQDIGDDDKGTYYCAYRESHRGYYYKVFGSGTKLIVSDKGSSAPENYEIMQEEHEKQVVYVCLIEKFYPEVIRVKWTDEANKEVTQNVVKGDVWKSPGEDKYSVSTWLSVPLESKNKIYSCTYEHESGGNSLSTQDLFPVPSSERSPQEQDCGTQSGNSTVVNRDHMTHKAAQLVYVVLLLKSSMYYVIVLFFFFKYRTRTAAKPSGKKT", "length": 344, "header": "tr|A0A1D5PLB4-1|A0A1D5PLB4_CHICK Isoform 1 of TCR gamma alternate reading frame protein OS=Gallus gallus OX=9031 GN=TARP PE=4 SV=2 CANONICAL=A0A1D5PLB4-1" }, "locus": { "chromosome": "2", "start_pos": 49099823, "end_pos": 49011583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042871.1", "url": "https://www.ensembl.org/id/ENSGALT00010042871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025361.1", "url": "https://www.ensembl.org/id/ENSGALP00010025361.1" } ] } }, { "isoform_ac": "A0A8V0YW96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW96/entry", "sequence": { "sequence": "MLLLAALTVTTAWSYGFAQETPIQSPVSITMSRGNTDLKCHFKDFSGNFDNTVIHWYQQKENKAPVRMMYFTSGRTEVDESFQRHRYRIQTISRQKLCTLTIRNVIPDDAATYYCAYWDPHRILLQSFRLWYKAHCIRQRKFSTREL", "length": 147, "header": "tr|A0A8V0YW96-1|A0A1D5PLB4_CHICK Computationally mapped isoform of TCR gamma alternate reading frame protein OS=Gallus gallus OX=9031 GN=TARP PE=4 SV=1 CANONICAL=A0A1D5PLB4-1" }, "locus": { "chromosome": "2", "start_pos": 49043083, "end_pos": 49014138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042866.1", "url": "https://www.ensembl.org/id/ENSGALT00010042866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025356.1", "url": "https://www.ensembl.org/id/ENSGALP00010025356.1" } ] } }, { "isoform_ac": "A0A8V0Z4C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C6/entry", "sequence": { "sequence": "MLLLPMLALAEAWLHPFPSPWRLHWQQQQEAVLRTPAGSRLAVLAVFSLLLIDGHAQVLLQQRQPSATRERSKTVTIQCHVEGIADFHNAYIHWYRQMPAKAPERLLYVTAVAQVSYDSDSYKNKYTSSKMGNKICTLSVQDIGDDDKGTYYCAYSVLW", "length": 159, "header": "tr|A0A8V0Z4C6-1|A0A8V0Z4C6_CHICK Computationally mapped isoform of TCR gamma alternate reading frame protein OS=Gallus gallus OX=9031 GN=TARP PE=4 SV=1 CANONICAL=A0A1D5PLB4-1" }, "locus": { "chromosome": "2", "start_pos": 49099838, "end_pos": 49022721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042869.1", "url": "https://www.ensembl.org/id/ENSGALT00010042869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025359.1", "url": "https://www.ensembl.org/id/ENSGALP00010025359.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLB4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PLB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PLB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLB4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PLB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLB4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 148, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PLE8-1", "uniprot_ac": "A0A1D5PLE8", "uniprot_id": "A0A1D5PLE8_CHICK", "mass": { "chemical_mass": 45503.0, "monoisotopic_mass": 45503.0 }, "refseq": { "ac": "NP_001186351", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" }, "gene_names": [ { "name": "METTL15", "type": "recommended", "evidence": [ { "id": "A0A1D5PLE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ] }, { "name": "METT5D1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "name": "METTL15P1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "name": "METTL15", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] } ], "protein_names": [ { "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "type": "recommended", "evidence": [ { "id": "A0A1D5PLE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8/entry#names_and_taxonomy" } ] }, { "name": "12S rRNA N(4)-cytidine methyltransferase METTL15 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "name": "Methyltransferase 5 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PLE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8/entry#names_and_taxonomy" } ] }, { "name": "Methyltransferase-like protein 15", "type": "synonym", "evidence": [ { "id": "A0A1D5PLE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8/entry#names_and_taxonomy" } ] }, { "name": "methyltransferase 5 domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "name": "methyltransferase like 15 pseudogene 1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "name": "putative S-adenosyl-L-methionine-dependent methyltransferase METT5D1", "type": "synonym", "evidence": [ { "id": "NP_001186351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01011965.1, SRR13267649.4362.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Dec 8, 2010 this sequence version replaced XP_419643.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001186351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351" } ] }, { "annotation": "N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8#function" }, { "database": "UniProtKB", "id": "ARBA00056391", "url": "https://www.uniprot.org/uniprotkb/ARBA00056391#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL15", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8", "locus": { "chromosome": "5", "start_pos": 4207458, "end_pos": 4105931, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022379", "url": "https://www.ensembl.org/id/ENSGALG00010022379" } ] } } ], "crossref": [ { "id": "A0A1D5PLE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012153", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421606", "url": "https://www.ncbi.nlm.nih.gov/gene/421606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421606", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLE8", "url": "https://www.orthodb.org/?gene=A0A1D5PLE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11265:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11265:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186351", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "62524", "url": "https://www.rhea-db.org/rhea/62524", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MINSKMLSQCLCQVNKCLLHNLKLNPIKLAALSRRIHSSVKQLSEYELTEQTTQKSETKKLPDSTENKNFGRLHVPVMMEEVVSCLSPQSGQCFLDMTFGAGGHSTALLEKASNITIYALDRDPTAYKIAQQLSESYPKQIQALLGQFSQSEALLISSGVEPGTLDGVLLDAGCSSMQFDTPERGFSLQKDGPLDMRMDSDRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIVQARSIYPITRTQQLASIVAGAFPASALYARKDLLQRPTHIATKTFQGLRIFVNDELHELFIGLKTAEKFLKPGGRLVALSFHSLEDRIIKRFLHGIDMTEKYNLGSKQKIRQALKNCSKEEDTHEFPHGKSNSKWTFIQKKVLTPQAKDILTNPRARSAKLRAAVKL", "length": 409, "header": "tr|A0A1D5PLE8-1|A0A1D5PLE8_CHICK Isoform 1 of 12S rRNA N(4)-cytidine methyltransferase METTL15 OS=Gallus gallus OX=9031 GN=METTL15 PE=3 SV=1 CANONICAL=A0A1D5PLE8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8/entry", "sequence": { "sequence": "MINSKMLSQCLCQVNKCLLHNLKLNPIKLAALSRRIHSSVKQLSEYELTEQTTQKSETKKLPDSTENKNFGRLHVPVMMEEVVSCLSPQSGQCFLDMTFGAGGHSTALLEKASNITIYALDRDPTAYKIAQQLSESYPKQIQALLGQFSQSEALLISSGVEPGTLDGVLLDAGCSSMQFDTPERGFSLQKDGPLDMRMDSDRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIVQARSIYPITRTQQLASIVAGAFPASALYARKDLLQRPTHIATKTFQGLRIFVNDELHELFIGLKTAEKFLKPGGRLVALSFHSLEDRIIKRFLHGIDMTEKYNLGSKQKIRQALKNCSKEEDTHEFPHGKSNSKWTFIQKKVLTPQAKDILTNPRARSAKLRAAVKL", "length": 409, "header": "tr|A0A1D5PLE8-1|A0A1D5PLE8_CHICK Isoform 1 of 12S rRNA N(4)-cytidine methyltransferase METTL15 OS=Gallus gallus OX=9031 GN=METTL15 PE=3 SV=1 CANONICAL=A0A1D5PLE8-1" }, "locus": { "chromosome": "5", "start_pos": 4206346, "end_pos": 4107178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054415.1", "url": "https://www.ensembl.org/id/ENSGALT00010054415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032868.1", "url": "https://www.ensembl.org/id/ENSGALP00010032868.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421606", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit assembly", "id": "GO:0180026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180026", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "rRNA (cytosine-N4-)-methyltransferase activity", "id": "GO:0071424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071424", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLE8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "62524", "name": "", "equation": "cytidine(839) in 12S rRNA + S-adenosyl-L-methionine = N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "62524", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62524" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PLE8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 409, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PLE8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLE8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PLG6-1", "uniprot_ac": "A0A1D5PLG6", "uniprot_id": "A0A1D5PLG6_CHICK", "mass": { "chemical_mass": 202923.0, "monoisotopic_mass": 202923.0 }, "refseq": {}, "gene_names": [ { "name": "VIRMA", "type": "recommended", "evidence": [ { "id": "A0A1D5PLG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ] } ], "protein_names": [ { "name": "Vir like m6A methyltransferase associated", "type": "synonym", "evidence": [ { "id": "A0A1D5PLG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VIRMA", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6", "locus": { "chromosome": "2", "start_pos": 125737847, "end_pos": 125764386, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012275", "url": "https://www.ensembl.org/id/ENSGALG00010012275" } ] } } ], "crossref": [ { "id": "ENSGALG00000031131", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420227", "url": "https://www.ncbi.nlm.nih.gov/gene/420227", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420227", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWLEPLP", "url": "https://omabrowser.org/oma/group/YWLEPLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLG6", "url": "https://www.orthodb.org/?gene=A0A1D5PLG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Y8Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEY2", "url": "https://www.orthodb.org/?gene=A0A8V0YEY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23185:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23185:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVDTATELLFLDTFKHQSAEQSTNIDVVRFPCVVYINEVRVIPPGVRAHTSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNAKVNTDGLVLRGWYNCLTLAIYGSVDRVITHDRESPPPPPPPPPPPQQQPGLKRTPKHVDGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDEPMPVSVVGEKEDDVDHREDYFEPISPDRTSIHQESQYSDEGEVEEDQPEEGDDEEDVDVEEEEEEDDDDGHTVESIPDEDEEEEEEDEDEEDGEEEEEGEGDDGYEQISSDEDGIADLERETFKYPSFDIEYTPEDLASVPPVTYEPFERELGPLLYFNCPYKTVFENEVAKIKDLDPEKENSGAVEASVKLTELLELYQEERGAKWVTALEEIPSLIVKGLSYLQVKDTKQDYITQLVDWTLQALSLQVALKQPIALNVRQLKAGTKLVSSLGECGTQGITALLQAGVINVLFELLFADHVSSSLKLNAFKALDSVISTTEGMEVFLRGGADAHEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEILSDIKKVVDQLAENTPSLPNHTETEQDQDLAGLDRANQEYENDVEAPMDMDHLLESSNISEGEVEKLVSLLEEIFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLECITLLLSIPVTGAHPGVLQAIRDLLRFLAQSQKGLLFFISEYEATNLLIRALCQFSDPDQEEGLQSDGANEDTFALWLLHSTQTLQCISELFCHFQRFTASEETDHSDLLGTLHNLYLITFNPVGRSAVAHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILVLLVVQSSSDVQMLEQHSAPLLKLCKADENNTKLQELSKWLEPLKNLRFEINCIPNLIEYIKQNIDSLMTPDGVGLPTALRVLCHVACPPPMVEGQQKDLKWNLAVIQLFSSEGMDTFIRVLQKLNSILIQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVSLHMLLCSIPLSGRLDSDEQKLQNDIVDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILRIPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLIQEIVRSFSGSSCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSNTEDKEKQYTGQTTRLLALLDALASHKACKLAILHLINGTTKGDEKYGEVFQELLALMRSVGDNVTHQQSAEYVTSILQSLCDQDIALILPSSSEGSVSELEQLSNSLPNKDLMPSICDCLMETLTNSESSYNCLLTCIRTMMFLTEHDYGFYHLKSSLRKHSSALYTVLKRIITSFSKDTGELASSFLDFMRQLLNSDTLGCCGDDGSLMEVDGSHPGRTLGLTTAELKHLLQSKEETPENLLLDLEKHVMDHSKEDDGLESLLDNIVGVRQMLESAGDACPLSDQDVEPILSAPDSLQNLFNNRTTYVLADVMDDQLKSMWFSPFQAEEIDTDLDMVKVDLIELSEKGCSDFDLQAELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVAPDGIPPAKRPPKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGARGSSWSAQSTPRGTYNDSRGGQSNFNRGPLPPLRPLSSAGYRPSPRDRASRGRGGIGPSWTSANSSSSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1821, "header": "tr|A0A1D5PLG6-1|A0A1D5PLG6_CHICK Isoform 1 of Vir like m6A methyltransferase associated OS=Gallus gallus OX=9031 GN=VIRMA PE=1 SV=1 CANONICAL=A0A1D5PLG6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6/entry", "sequence": { "sequence": "MAVDTATELLFLDTFKHQSAEQSTNIDVVRFPCVVYINEVRVIPPGVRAHTSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNAKVNTDGLVLRGWYNCLTLAIYGSVDRVITHDRESPPPPPPPPPPPQQQPGLKRTPKHVDGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDEPMPVSVVGEKEDDVDHREDYFEPISPDRTSIHQESQYSDEGEVEEDQPEEGDDEEDVDVEEEEEEDDDDGHTVESIPDEDEEEEEEDEDEEDGEEEEEGEGDDGYEQISSDEDGIADLERETFKYPSFDIEYTPEDLASVPPVTYEPFERELGPLLYFNCPYKTVFENEVAKIKDLDPEKENSGAVEASVKLTELLELYQEERGAKWVTALEEIPSLIVKGLSYLQVKDTKQDYITQLVDWTLQALSLQVALKQPIALNVRQLKAGTKLVSSLGECGTQGITALLQAGVINVLFELLFADHVSSSLKLNAFKALDSVISTTEGMEVFLRGGADAHEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEILSDIKKVVDQLAENTPSLPNHTETEQDQDLAGLDRANQEYENDVEAPMDMDHLLESSNISEGEVEKLVSLLEEIFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLECITLLLSIPVTGAHPGVLQAIRDLLRFLAQSQKGLLFFISEYEATNLLIRALCQFSDPDQEEGLQSDGANEDTFALWLLHSTQTLQCISELFCHFQRFTASEETDHSDLLGTLHNLYLITFNPVGRSAVAHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILVLLVVQSSSDVQMLEQHSAPLLKLCKADENNTKLQELSKWLEPLKNLRFEINCIPNLIEYIKQNIDSLMTPDGVGLPTALRVLCHVACPPPMVEGQQKDLKWNLAVIQLFSSEGMDTFIRVLQKLNSILIQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVSLHMLLCSIPLSGRLDSDEQKLQNDIVDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILRIPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLIQEIVRSFSGSSCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSNTEDKEKQYTGQTTRLLALLDALASHKACKLAILHLINGTTKGDEKYGEVFQELLALMRSVGDNVTHQQSAEYVTSILQSLCDQDIALILPSSSEGSVSELEQLSNSLPNKDLMPSICDCLMETLTNSESSYNCLLTCIRTMMFLTEHDYGFYHLKSSLRKHSSALYTVLKRIITSFSKDTGELASSFLDFMRQLLNSDTLGCCGDDGSLMEVDGSHPGRTLGLTTAELKHLLQSKEETPENLLLDLEKHVMDHSKEDDGLESLLDNIVGVRQMLESAGDACPLSDQDVEPILSAPDSLQNLFNNRTTYVLADVMDDQLKSMWFSPFQAEEIDTDLDMVKVDLIELSEKGCSDFDLQAELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVAPDGIPPAKRPPKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGARGSSWSAQSTPRGTYNDSRGGQSNFNRGPLPPLRPLSSAGYRPSPRDRASRGRGGIGPSWTSANSSSSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1821, "header": "tr|A0A1D5PLG6-1|A0A1D5PLG6_CHICK Isoform 1 of Vir like m6A methyltransferase associated OS=Gallus gallus OX=9031 GN=VIRMA PE=1 SV=1 CANONICAL=A0A1D5PLG6-1" }, "locus": { "chromosome": "2", "start_pos": 125764371, "end_pos": 125738037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029403.1", "url": "https://www.ensembl.org/id/ENSGALT00010029403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017078.1", "url": "https://www.ensembl.org/id/ENSGALP00010017078.1" } ] } }, { "isoform_ac": "A0A8V0Y8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q3/entry", "sequence": { "sequence": "MAVDTATELLFLDTFKHQSAEQSTNIDVVRFPCVVYINEVRVIPPGVRAHTSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNAKVNTDGLVLRGWYNCLTLAIYGSVDRVITHDRESPPPPPPPPPPPQQQPGLKRTPKHVDGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDEPMPVSVVGEKEDDVDHREDYFEPISPDRTSIHQESQYSDEGEVEEDQPEEGDDEEDVDVEEEEEEDDDDGHTVESIPDEDEEEEEEDEDEEDGEEEEEGEGDDGYEQISSDEDGIADLERETFKYPSFDIEYTPEDLASVPPVTYEPFERELGPLLYFNCPYKTVFENEVAKIKDLDPEKENSGAVEASVKLTELLELYQEERGAKWVTALEEIPSLIVKGLSYLQVKDTKQDYITQLVDWTLQALSLQVALKQPIALNVRQLKAGTKLVSSLGECGTQGITALLQAGVINVLFELLFADHVSSSLKLNAFKALDSVISTTEGMEVFLRGGADAHEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEILSDIKKVEKLVSLLEEIFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLECITLLLSIPVTGAHPGVLQAIRDLLRFLAQSQKGLLFFISEYEATNLLIRALCQFSDPDQEEGLQSDGANEDTFALWLLHSTQTLQCISELFCHFQRFTASEETDHSDLLGTLHNLYLITFNPVGRSAVAHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILVLLVVQSSSDVQMLEQHSAPLLKLCKADENNTKLQELSKWLEPLKNLRFEINCIPNLIEYIKQNIDSLMTPDGVGLPTALRVLCHVACPPPMVEGQQKDLKWNLAVIQLFSSEGMDTFIRVLQKLNSILIQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVSLHMLLCSIPLSGRLDSDEQKLQNDIVDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILRIPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLIQEIVRSFSGSSCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSNTEDKEKQYTGQTTRLLALLDALASHKACKLAILHLINGTTKGDEKYGEVFQELLALMRSVGDNVTHQQSAEYVTSILQSLCDQDIALILPSSSEGSVSELEQLSNSLPNKDLMPSICDCLMETLTNSESSYNCLLTCIRTMMFLTEHDYGFYHLKSSLRKHSSALYTVLKRIITSFSKDTGELASSFLDFMRQLLNSDTLGCCGDDGSLMEVDGSHPGRTLGLTTAELKHLLQSKEETPENLLLDLEKHVMDHSKEDDGLESLLDNIVGVRQMLESAGDACPLSDQDVEPILSAPDSLQNLFNNRTTYVLADVMDDQLKSMWFSPFQAEEIDTDLDMVKVDLIELSEKGCSDFDLQAELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVAPDGIPPAKRPPKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGARGSSWSAQSTPRGTYNDSRGGQSNFNRGPLPPLRPLSSAGYRPSPRDRASRGRGGIGPSWTSANSSSSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1764, "header": "tr|A0A8V0Y8Q3-1|A0A1D5PLG6_CHICK Computationally mapped isoform of Vir like m6A methyltransferase associated OS=Gallus gallus OX=9031 GN=VIRMA PE=1 SV=1 CANONICAL=A0A1D5PLG6-1" }, "locus": { "chromosome": "2", "start_pos": 125764371, "end_pos": 125738037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029405.1", "url": "https://www.ensembl.org/id/ENSGALT00010029405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017080.1", "url": "https://www.ensembl.org/id/ENSGALP00010017080.1" } ] } }, { "isoform_ac": "A0A8V0YEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY2/entry", "sequence": { "sequence": "MAVDTATELLFLDTFKHQSAEQSTNIDVVRFPCVVYINEVRVIPPGVRAHTSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNAKVNTDGLVLRGWYNCLTLAIYGSVDRVITHDRESPPPPPPPPPPPQQQPGLKRTPKHVDGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDEPMPVSVVGEKEDDVDHREDYFEPISPDRTSIHQESQYSDEGEVEEDQPEEGDDEEDVDVEEEEEEDDDDGHTVESIPDEDEEEEEEDEDEEDGEEEEEGEGDDGYEQISSDEDGIADLERETFKYPSFDIEYTPEDLASVPPVTYEPFERELGPLLYFNCPYKTVFENEVAKIKDLDPEKENSGAVEASVKLTELLELYQEERGAKWVTALEEIPSLIVKGLSYLQVKDTKQDYITQLVDWTLQALSLQVALKQPIALNVRQLKAGTKLVSSLGECGTQGITALLQAGVINVLFELLFADHVSSSLKLNAFKALDSVISTTEGMEVFLRGGADAHEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEILSDIKKVVDQLAENTPSLPNHTETEQDQDLAGLDRANQEYENDVEAPMDMDHLLESSNISEGEVEKLVSLLEEIFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLECITLLLSIPVTGAHPGVLQAIRDLLRFLAQSQKGLLFFISEYEATNLLIRALCQFSDPDQEEGLQSDGANEDTFALWLLHSTQTLQCISELFCHFQRFTASEETDHSDLLGTLHNLYLITFNPVGRSAVAHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILVLLVVQSSSDVQMLEQHSAPLLKLCKADENNTKLQELSKWLEPLKNLRFEINCIPNLIEYIKQNIDSLMTPDGVGLPTALRVLCHVACPPPMVEGQQKDLKWNLAVIQLFSSEGMDTFIRVLQKLNSILIQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVSLHMLLCSIPLSGRLDSDEQKLQNDIVDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILRIPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLIQEIVRSFSGSSCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSNTEDKEKQYTGQTTRLLALLDALASHKACKLAILHLINGTTKGDEKYGEVFQELLALMRSVGDNVTHQQSAEYVTSILQSLCDQDIALILPSSSEGSVSELEQLSNSLPNKDLMPSICDCLMETLTNSESSYNCLLTCIRTMMFLTEHDYGFYHLKSSLRKHSSALYTVLKRIITSFSKDTGELASSFLDFMRQLLNSDTLGCCGDDGSLMEVDGSHPGRTLGLTTAELKHLLQSKEETPENLLLDLEKHVMDHSKEDDGLESLLDNIVGVRQMLESAGDACPLSDQDVEPILSAPDSLQNLFNNRTTYVLADVMDDQLKSMWFSPFQAEEIDTDLDMVKVDLIELSEKGCSDFDLQAELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVAPDGIPPAKRPPKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGMLSFLLELE", "length": 1731, "header": "tr|A0A8V0YEY2-1|A0A1D5PLG6_CHICK Computationally mapped isoform of Vir like m6A methyltransferase associated OS=Gallus gallus OX=9031 GN=VIRMA PE=1 SV=1 CANONICAL=A0A1D5PLG6-1" }, "locus": { "chromosome": "2", "start_pos": 125764371, "end_pos": 125739634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029399.1", "url": "https://www.ensembl.org/id/ENSGALT00010029399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017076.1", "url": "https://www.ensembl.org/id/ENSGALP00010017076.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420227", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420227", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B4B7-1", "protein_name": "Protein virilizer homolog isoform X1", "gene_name": "virma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGDSAMELLFLDTFKHQNAELTNVDVVRFPYGVLITEVRVIPPGIKAHSNLPDSRAFGETAPHAFQLDLFFNNVSKPNSPVFDRLGSLEYDENKSIIFRPNGKINTDGLVLRGWYTCLTLAVYGTAERPHSHERDSPPPPPPPPPQQQQIGSKRLIKLEWENEDQFNGSPPRPQPRGPRTPPGPPPPDDDDEEAMPAPGQCPVKVENTEHPGDDYLEPVSPERGSLPADETYSDAEQEDDEGPADEEEDDVQSEGTEGDEDDEEDEVGDDVTDEDGEGDDGYEQISSDEEDLESGAFKLPAFDLDYTPEDLASLPTVQYDPYERELRPLQHFTPPHITRYEAELKRLKTVDIEDSSSSWAESAAKLSELLEAWGEAQGAERGAGWVTALEEVPAFLVKGMSFLSIKDPDGQSEKLKQLVDWSCEALSLDVALAQPIALNLRQLKAGTKLVSALADCGAQAVQDLLEKGIVGRLLGLLFAEHVSSTLKLNVLRSLDSIISEPQGIEAMLRDRHHHDDDGTSGYQRLLDLFLLDQTVRVATAGAAILHKGHLYEVLTDLQKTASVWAERHPTVGEVAEREGSESEAGERDRESTEREGEERERETQEAERESPMDIDTLLESASLSEADLERLQGLLEELLHLLETAPHCMVQPPGKAFPTNVRITGPPERDDPYPTLYRYMHACHLLESLGVVLSYPATCAHIGVLQAVRELMRFLSQSQQGLLFLLSQHETINLLLRLLTPLTHLTPPSHLAPLTPLSEVEGEEAAAGGEGLMDDGFWVWLMQTLHALQGIAELNGAELEDGDNPDVLATLHSLYLISFSSTGRNAVAHTFSLDNNLSCLINLIEFHAKDGQGDGKARKSVTYNYACMLVLLVIQTSSDLRMMEHYAAPLLLVCKADENNAKLQELSKWLEPLEKLHFDISGIPMLIDYIKQNLENLMTADGVGLVTALRVLCHIACPPATVPGQQKDLKWNQAIIALFSAEGMDTFIKVLQKLTSLLLLPWRLHGPMGPTAQRLMMLSVASCSLRLIRAMLTELLCGGTCEFRDVRVPSVCVTLHKILCSTPSTGRLDAEELRIQGDVTEILLTFTHAVSEQETGSEETVAGNSWSLMLKEVLNSILAAPENIYSSLSLLSELLPLPLPMQTTQALSVQDIGVAMNTRKLWSVHLHAQARVLQEVLRCACVSSCPPLFSMLRRVCVQLCDLAAPTATLVMRTLLEQLQEEMQQEAAGSRLIRVLALLDSLASQRACKVAMLALLSGSARSDTRSEGKVEDKLSDILPSLLAMLVLPADVGLSAQQNAELMASILQSLCDQDVSLVVSGSGEASVSEAELLANALPTKEMMTSICEGMLDVLGNTHSSYTLQLTCLRTMMFLTEHDYGLYHLKSSLKKHTTAISSLIRREITSFNKEFAELLSALFDFLRQILNSEAMFLRSAFYRHHHADEDMDSRSLALSVSDMKQLLQWKEDSGEHLLCELEKHITKLCKEDESLEALLENVVGLRQIIESSGDAQTNAEPETEPSLPAPEPLQTQFNHRTVYVLSDVLDEQLKALWFSPFQPDEMETEVDMVKVDLVALAQQCCTELDLKAELERSFLSEPSSPGHSKPSKGFRLGKHKHETFITSRYTSGRSDYVEPAKRAHIMAAPRGRGRGSFGQLSRPHDIFRQRKQNTSRPPSMHVDDFLAAEFKDVGPPTGLTLPKRPPKGGGAKPPTRGMFTGGTRGRGFQSHTRFFTPPAPKSVLLAGNYPRREGGRGSTWSTPVTAVTHRGTYSEPRGGQSNFTRPLPSRQPPTGAYRLAPRDRATRGRGTGLSWLSAGVSVGGGGGVSGGGRGQGKFSSGGSGGGRGRHVRSFTR", "length": 1850 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AIV2-1", "protein_name": "Protein virilizer homolog", "gene_name": "Virma", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPTLKRNLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLPVSGDKEEDVPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEPQEEGEDDEDDVDVEEEEDEDEDDCHTVDSIPDDEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTPEDLASVPPMTYDPYDRELAPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAVEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTEQDSLGQLVDWTMQALNLQVAFRQPIALNVRQLKAGTKLVTSLAECGAPGVTELLQAGVINVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQNEKSGYQRLLELILLDQTVRVVTAGSAILQKCHFYEILSEIKRLGDHIAEKTSAVPNHSEPDQDTDAVLERANPDYENEVEASMDMDLLESSIISEGEIEKLTNLLEEVFHVMETAPHTMTQPPVKSFPTIARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPITSAHQGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGADDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACVLTLVVAQSSSGVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVTRQQCVEYVTSILQSLCDQDIALILPSPSEGPASELEQLSNSLPSKELMTAICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELASASLDFMRQILNADAMGCCGDDSGLMEVEGAHPPRTMSLNAAELKQLLQSKEESPESLFLELEKLVLEHSKDDDSLESLLDNVIGLKQMLESSGEPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRSKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASTNSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1811 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZKC9-1", "protein_name": "Vir like m6A methyltransferase associated", "gene_name": "Virma", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRGRLMVLRVLIWHNFLLFARTHGPSQASWRLRSGERRDLDHRKHRSPLPSFFLPFWAFRRRPPPRWRRRGLRLKVVRCDGIGRGLRRRRPIYRKCCSFPLAGASAWEVGELPRKSSPGPPPAANMAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVLSHDRDSPPPPPPPPPPPQPQPTLKRSLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLPVSGDKEEDVPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEDDEDDVDVDEEEDEDEDDCHTVDSIPDDDEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTPEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEINRMKDQGPDKENSGAIEASLKLTELLDLYHEDRGAKWVTALEEVPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQVAFRQPIALNVRQLKAGTKLVTSLAECGAPGVTELLQAGVISVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQSEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHIAEKTSSVPNPSEPDHDTDAVLERANPDYENEVEASMDMDLLESSNISEGEIEKLINLLEEVFHLMETAPHTMIQPPVKSFPTIARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPITSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVDDAFALWLQDSTQTLQCVTELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDEKYAEIFQDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSPSEGPGSELEQLSNSLPSKELMAAICDCLLATLANSESTYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELTSASLDFMRQILNSDAMGCCGDDSGLMEVESAHPPRTMSINAAELKQLLQSKEESPESLFLELEKLVLEHSKEDDSLESLLDNVIGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRAKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASTNSGSGGSRGKSKQPKTFHHHH", "length": 1931 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RY51-1", "protein_name": "Vir like m6A methyltransferase associated", "gene_name": "VIRMA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPLPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEVEDDEDDGDVEEEEDEDEDDRHTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRLKDQGPDKENSGAIEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDALDQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVMGLLQAGVINGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSKQSEKSGYQKLVELILLDQTVRVVTAGSAILQKCHFYEILSEIKKLGDHLAEKTSSVPNHSEPDHDTDTGLERTNPDYENEVDASMDMDLLESSNISEGEIEKLISLLEEVFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVVRQQCVEYITSILQSLCDQDIALILPNSSEGSISELEQLSNSLPNKELMASICDCLLAVLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSNALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTMGCCGDDSGLMEVEGAHPSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDNVVGLKQMLESSGDPLPLGDQDIEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGTYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1812 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q69YN4-1", "protein_name": "Protein virilizer homolog", "gene_name": "VIRMA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQAGVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPEYENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNKELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1812 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1R5-1", "protein_name": "Protein virilizer", "gene_name": "vir", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADVDDGSELLFFDTFSHEEVTDINLDLVQFPKPVFITQVRIIPLGARVQADFPGGVRLGATNPSKFDLEFFVNDLGMPAASAFENLGLLRYNQNDCIHLDCSQEKIVTDGLVLRGWYSTITLAIYGIFTNSVTEPIASPTLPCEPVGPEIANLSGEVLLQEDVLKDEWQEPMQAELLTAHKGNVSDYDPEDMEYGMSRDHYHQHAEEQEQREMRRLRRSTHSTDHSPPPPRRSHTHSESNDREYIRCSRDKGSRDWSRSPEYSSHRSRRKRSERSRSVVDEHKWPRTPPASIDSPTRPRSPDTMDYEDEDSRSHYKMQSSHYRHSSESLHRGERDRDDEDRSCTPQEQFEPILSDDEIIGDDEEDDAVDAAAIAEYERELEAAAAAAPPAIDAFEPWQKPLLVFEGDMAAHFCKELETLKLLFKKLVLQTRCENVNAFSEEHGASVDEREQFVYLGEQLNNQLGYLAQHYKRRNFVLQQFFGNDELHLRQAANVLQIALSFQAACMQPQPAFKIRHIKLGARMAELLGSSEELFQHLLKEHKFDIFEAVFRLYHEPYMALSIKLQLLKAVYALLDTRMGIEHFMGAKNNGYQMIVEAIKTAKLTRTKYALQAIIKKLHLWEGLESVQIWCRRLFVDRIIIPGNRDQMEDTVITCQQIEFAFEMLMDALFSSQLSYLQPRRFLPVSKKFEVVTDPTAQRSFGNALQSYLGQNSLAESLLVMLANCKELPATTYLSMLDLMHTLLRSHVGIDYFVDDAFPVTQTIVAILLGLDEVPRNPEEKEEKAEKSDAEDKAMEVENEAVEAGGEKPTPPTADEEGKPVAAPISVPAPAAAPQVRPRPILRPVLPRLARLGIEMSYKVQTRYHLDAIAYAAAAPEYDAVKLATHMHAIYSQTCDPAGRQHTVEVLGLNNNLKIFMDLIKKEQRLQTQRQLSSPGTKYKSPVLSYAVDMVDACVRYCEQLDYLIEHGGVILELAKNHETFEPSVSAVLQEMYVYMKPLEAINVFVYDDIMPLVEVIGRSLDYLTTFPGDLIMAMRILRYLSISKPLAGQKAPPVTEELKHRFVALQLYAADGVQLCIQIMERLCAYFEQPGAHAPALMTIQGVHCCQIMLPTLQILRELLSYAILCRDGTYKDLTAIDHLVKVYYLLYYFPTRCQAGPEVEQCKMEVVQTLLAYTQPNEQDEESLHKSLWTLMIREVLKNVDGPAHFIPGLKLLAELLPLPLPMPQPLCDQLQQQHKQRLITERKLWSAHLHPQSGQIAKLVEALAPSSFPQLSELLQRVCMQLSDLAPNMTLLIAKTITELLCNEYQTSNCIPTTNLERLLRFSTRLCAFAPLKSSMLSILSGKFWELFQSLLALNEFNDVVSNCQEAVHRILDSFLDSGISLISHKSTASPALNLAAALPPKELIPRIIDAVFSNLTSVEVTHGISILAVRNLVILTEHDFTFYHLAQLLKQKITEFQAWMERVILHNETVEYNANIESLILLLRSLTQIEPPPAMSAMPHRTLKLGATELAQLVEFQDIELAKPPVLSRILTVMEKHKAVANEAALSDLKQLILLQASKQEILAGTSTETPPEAEGEANPSASSCSASLTVEPYLPQAEGIVTQYEARPIFTRFCATAENAQLTARYWLDPLPIELIEDMNEPIYERIACDLTDLANVCLNPDLNVAGDSKRVMNLSGSPQSNREMTPTAPCFRTRRVEVEPATGRPEKKMFVSSVRGRGFARPPPSRGDLFRSRPPNTSRPPSLHVDDFLALETCGAQPTGPTGYNKIPSMLRGSRVGRNRGSRISAAAAFRQKKMMRIGSPSSWAESPGSYRSASDSHFSSSDSHYSSPHYSGRPRGRGLRSRPSYLR", "length": 1854 }, "evidence": [ { "id": "A0A1D5PLG6", "url": "https://omabrowser.org/oma/group/A0A1D5PLG6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1255, "end_pos": 1257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1281, "end_pos": 1283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1522, "end_pos": 1524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1653, "end_pos": 1655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1723, "end_pos": 1725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1746, "end_pos": 1748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1794, "end_pos": 1796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PLG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLG6" }, { "id": "PF15912", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15912" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Virilizer N-terminal", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 265, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"A0A1D5PLQ8-1", "uniprot_ac": "A0A1D5PLQ8", "uniprot_id": "A0A1D5PLQ8_CHICK", "mass": { "chemical_mass": 32599.0, "monoisotopic_mass": 32599.0 }, "refseq": { "ac": "NP_001299812", "name": "tripartite motif protein 39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" }, "gene_names": [ { "name": "TRIM39.1", "type": "recommended", "evidence": [ { "id": "A0A1D5PLQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLQ8" } ] }, { "name": "TRIM39.1", "type": "synonym", "evidence": [ { "id": "NP_001299812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" } ] } ], "protein_names": [ { "name": "BR", "type": "synonym", "evidence": [ { "id": "NP_001299812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" } ] }, { "name": "E3 ubiquitin-protein ligase TRIM39-like", "type": "synonym", "evidence": [ { "id": "NP_001299812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" } ] }, { "name": "Tripartite motif containing 39.1", "type": "synonym", "evidence": [ { "id": "A0A1D5PLQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLQ8/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif protein 39", "type": "synonym", "evidence": [ { "id": "NP_001299812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA103992290, SAMEA103992393 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000283.1. On Aug 20, 2015 this sequence version replaced XP_004945715.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001299812", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299812" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLQ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM39.1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLQ8", "locus": { "chromosome": "16", "start_pos": 2130569, "end_pos": 2134950, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002798", "url": "https://www.ensembl.org/id/ENSGALG00010002798" } ] } } ], "crossref": [ { "id": "A0A1D5PLQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLQ8", "database": 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"MALFSRHVYLAMGLNTRTVGQKWLEMFPRELRAKALEDLKNEIEKRQKSTAKHSEEISPLDTKAQGEKSQQSDVKSPITRCGKVTFQLPAGASPGPEERLCHSSWRNGALKETLKRLQASITLDPDTAHPDLILSEDRKSVKRGEGQQDLPDNPERFAYWPFVLGHQSFSAGRHCWEVEVGDEGDWAIGVARESIPRKGQLSLCPKGGIWGVEKWGGQVRALTTHKVTLLALRWVPRRVSVHLDYAGGTVAFFDADEGGLIFVFSHASFSGERVHPWLWVVGVRSKLRLCP", "length": 291, "header": "tr|A0A1D5PLQ8-1|A0A1D5PLQ8_CHICK Isoform 1 of Tripartite motif containing 39.1 OS=Gallus gallus OX=9031 GN=TRIM39.1 PE=4 SV=1 CANONICAL=A0A1D5PLQ8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLQ8/entry", "sequence": { "sequence": "MALFSRHVYLAMGLNTRTVGQKWLEMFPRELRAKALEDLKNEIEKRQKSTAKHSEEISPLDTKAQGEKSQQSDVKSPITRCGKVTFQLPAGASPGPEERLCHSSWRNGALKETLKRLQASITLDPDTAHPDLILSEDRKSVKRGEGQQDLPDNPERFAYWPFVLGHQSFSAGRHCWEVEVGDEGDWAIGVARESIPRKGQLSLCPKGGIWGVEKWGGQVRALTTHKVTLLALRWVPRRVSVHLDYAGGTVAFFDADEGGLIFVFSHASFSGERVHPWLWVVGVRSKLRLCP", "length": 291, "header": "tr|A0A1D5PLQ8-1|A0A1D5PLQ8_CHICK Isoform 1 of Tripartite motif containing 39.1 OS=Gallus gallus OX=9031 GN=TRIM39.1 PE=4 SV=1 CANONICAL=A0A1D5PLQ8-1" }, "locus": { "chromosome": "16", "start_pos": 2134249, "end_pos": 2130657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006481.1", "url": "https://www.ensembl.org/id/ENSGALT00010006481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003990.1", "url": "https://www.ensembl.org/id/ENSGALP00010003990.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747534", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PLQ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 291, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PLQ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLQ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"gene_names": [ { "name": "PHF12", "type": "recommended", "evidence": [ { "id": "A0A1D5PLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ] }, { "name": "PHF12", "type": "synonym", "evidence": [ { "id": "XP_015151564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151564" } ] } ], "protein_names": [ { "name": "PHD finger protein 12", "type": "recommended", "evidence": [ { "id": "A0A1D5PLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9/entry#names_and_taxonomy" } ] }, { "name": "PHD factor 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151564" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151564" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHF12", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9", "locus": { "chromosome": "19", "start_pos": 6367086, "end_pos": 6395003, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029677", "url": "https://www.ensembl.org/id/ENSGALG00010029677" } ] } } ], "crossref": [ { "id": "A0A1D5PLW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031368", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031368", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15533", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15533", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15534", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15534", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22703", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22703", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417580", "url": "https://www.ncbi.nlm.nih.gov/gene/417580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417580", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKVQARA", "url": "https://omabrowser.org/oma/group/CKVQARA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLW9", "url": "https://www.orthodb.org/?gene=A0A1D5PLW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEL6", "url": "https://www.orthodb.org/?gene=A0A8V1AEL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALM5", "url": "https://www.orthodb.org/?gene=A0A8V1ALM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANB0", "url": "https://www.orthodb.org/?gene=A0A8V1ANB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151564", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKSEDGEKRSRRPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGQVNGLVDKTGKRTTSPTSDADLLDRSSSSIRANAHARILERRASRPGTPTSNASTETPNSEQNDVDEDIIDVDDDSAIAEMDCGQPQLKRPFELLIAAAMERNPTQFQLPNELTCTTALPGTSKRRRKEETTGKNVKKAQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCRVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRKGLKVPDAIKSQYRLPPPLLAPAAIRDGELICNGIPEEPLQKHLLNTEHLASQTEQQEWLCSVVALQCSILKHLSAKQMTSLWDSEQTEKADIKPVIVADGTLANPYQAADKAPTPSLYSMSSCTSGITTQNSLSSSQSQQTLSQEDVNCSSCLDKSKKVSSCGTSNGPTASDVKVNGPHFYGVSSEPSAQLTDSQRLIGAGNTIPVLSHRQTWPRPLTPPATCGLLNHTIGTIVKTENVGGPVSCAQRGSVPVTSMPTSISSSCASLETTSTLQRKNVQTQIGPPLSADLRSMGSPLTATRALTPPQAAGDGISAVGSANRFCSPAPPSDGKVSPSTLSIGSALTLPSSLTSNSAAMLDLTSSLKAFMDGEIEINMLDEQLIKFLALQRIHQLFPSKAQSLASSVSAHQQSPVANHIEAQRKEVQARAVFYPLMGLGGAVNMCYRTLYIGTGADMDVCLTSYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKMAPTPPSSIVAKVQSVIKRHKSRKQEEEPHGEAAVMNSQAQGQHRKPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDTALVQDMDLEEKLSLKPHQVPVLRSNSVP", "length": 1009, "header": "tr|A0A1D5PLW9-1|A0A1D5PLW9_CHICK Isoform 1 of PHD finger protein 12 OS=Gallus gallus OX=9031 GN=PHF12 PE=4 SV=1 CANONICAL=A0A1D5PLW9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9/entry", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKSEDGEKRSRRPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGQVNGLVDKTGKRTTSPTSDADLLDRSSSSIRANAHARILERRASRPGTPTSNASTETPNSEQNDVDEDIIDVDDDSAIAEMDCGQPQLKRPFELLIAAAMERNPTQFQLPNELTCTTALPGTSKRRRKEETTGKNVKKAQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCRVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRKGLKVPDAIKSQYRLPPPLLAPAAIRDGELICNGIPEEPLQKHLLNTEHLASQTEQQEWLCSVVALQCSILKHLSAKQMTSLWDSEQTEKADIKPVIVADGTLANPYQAADKAPTPSLYSMSSCTSGITTQNSLSSSQSQQTLSQEDVNCSSCLDKSKKVSSCGTSNGPTASDVKVNGPHFYGVSSEPSAQLTDSQRLIGAGNTIPVLSHRQTWPRPLTPPATCGLLNHTIGTIVKTENVGGPVSCAQRGSVPVTSMPTSISSSCASLETTSTLQRKNVQTQIGPPLSADLRSMGSPLTATRALTPPQAAGDGISAVGSANRFCSPAPPSDGKVSPSTLSIGSALTLPSSLTSNSAAMLDLTSSLKAFMDGEIEINMLDEQLIKFLALQRIHQLFPSKAQSLASSVSAHQQSPVANHIEAQRKEVQARAVFYPLMGLGGAVNMCYRTLYIGTGADMDVCLTSYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKMAPTPPSSIVAKVQSVIKRHKSRKQEEEPHGEAAVMNSQAQGQHRKPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDTALVQDMDLEEKLSLKPHQVPVLRSNSVP", "length": 1009, "header": "tr|A0A1D5PLW9-1|A0A1D5PLW9_CHICK Isoform 1 of PHD finger protein 12 OS=Gallus gallus OX=9031 GN=PHF12 PE=4 SV=1 CANONICAL=A0A1D5PLW9-1" }, "locus": { "chromosome": "19", "start_pos": 6394633, "end_pos": 6367940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071778.1", "url": "https://www.ensembl.org/id/ENSGALT00010071778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044468.1", "url": "https://www.ensembl.org/id/ENSGALP00010044468.1" } ] } }, { "isoform_ac": "A0A8V1AEL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL6/entry", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKSEDGEKRSRRPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGQVNGLVDKTGKRTTSPTSDADLLDRSSSSIRANAHARILERRASRPGTPTSNASTETPNSEQNDVDEDIIDVDDDSAIAEMDCGQPQLKRPFELLIAAAMERNPTQFQLPNELTCTTALPGTSKRRRKEETTGKNVKKAQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCRVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRKGLKVPDAIKSQYRLPPPLLAPAAIRDGELICNGIPEEPLQKHLLNTEHLASQTEQQEWLCSVVALQCSILKHLSAKQMTSLWDSEQTEKADIKPVIVADGTLANPYQAADKAPTPSLYSMSSCTSGITTQNSLSSSQSQQTLSQEDVNCSSCLDKSKKVSSCGTSNGPTASDVKVNGPHFYGVSSEPSAQLTDSQRLIGAGNTIPVLSHRQTWPRPLTPPATCGLLNHTIGTIVKTENVGGPVSCAQRGSVPVTSMPTSISSSCASLETTSTLQRKNVQTQIGPPLSADLRSMGSPLTATRALTPPQAAGDGISAVGSANRFCSPAPPSDGKVSPSTLSIGSALTLPSSLTSNSAAMLDLTSSLKAFMDGAQRKEVQARAVFYPLMGLGGAVNMCYRTLYIGTGADMDVCLTSYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKMAPTPPSSIVAKVQSVIKRHKSRKQEEEPHGEAAVMNSQAQGQHRKPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDTALVQDMDLEEKLSLKPHQVPVLRSNSVP", "length": 961, "header": "tr|A0A8V1AEL6-1|A0A1D5PLW9_CHICK Computationally mapped isoform of PHD finger protein 12 OS=Gallus gallus OX=9031 GN=PHF12 PE=4 SV=1 CANONICAL=A0A1D5PLW9-1" }, "locus": { "chromosome": "19", "start_pos": 6394633, "end_pos": 6367940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071781.1", "url": "https://www.ensembl.org/id/ENSGALT00010071781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044471.1", "url": "https://www.ensembl.org/id/ENSGALP00010044471.1" } ] } }, { "isoform_ac": "A0A8V1ALM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM5/entry", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKSEDGEKRSRRPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGQVNGLVDKTGKRTTSPTSDADLLDRSSSSIRANAHARILERRASRPGTPTSNASTETPNSEQNDVDEDIIDVDDDSAIAEMDCGQPQLKRPFELLIAAAMERNPTQFQLPNELTCTTALPGTSKRRRKEETTGKNVKKAQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCRVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRKGLKVPDAIKSQYRLPPPLLAPAAIRDGELICNGIPEEPLQKHLLNTEHLASQTEQQEWLCSVVALQCSILKHLSAKQMTSLWDSEQTEKADIKPVIVADGTLANPYQAADKAPTPSLYSMSSCTSGITTQNSLSSSQSQQTLSQEDVNCSSCLDKSKKVSSCGTSNGPTASDVKVNGPHFYGVSSEPSAQLTDSQRLIGAGNTIPVLSHRQTWPRPLTPPATCGLLNHTIGTIVKTENVGGPVSCAQRGSVPVTSMPTSISSSCASLETTSTLQRKNVQTQIGPPLSADLRSMGSPLTATRALTPPQAAGDGISAVGSANRFCSPAPPSEIEINMLDEQLIKFLALQRIHQLFPSKAQSLASSVSAHQQSPVANHIEAQRKEVQARAVFYPLMGLGGAVNMCYRTLYIGTGADMDVCLTSYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKMAPTPPSSIVAKVQSVIKRHKSRKQEEEPHGEAAVMNSQAQGQHRKPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDTALVQDMDLEEKLSLKPHQVPVLRSNSVP", "length": 968, "header": "tr|A0A8V1ALM5-1|A0A1D5PLW9_CHICK Computationally mapped isoform of PHD finger protein 12 OS=Gallus gallus OX=9031 GN=PHF12 PE=4 SV=1 CANONICAL=A0A1D5PLW9-1" }, "locus": { "chromosome": "19", "start_pos": 6394633, "end_pos": 6367940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071780.1", "url": "https://www.ensembl.org/id/ENSGALT00010071780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044470.1", "url": "https://www.ensembl.org/id/ENSGALP00010044470.1" } ] } }, { "isoform_ac": "A0A8V1ANB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB0/entry", "sequence": { "sequence": "MGRRGAGGLRRSPGEVAGPLTTTAAIAARKEGTCCAAITAPPLSTSSAATLRSARKCCLQGSGCVTAAPCAERSENRRKSWGRSSSSIRANAHARILERRASRPGTPTSNASTETPNSEQNDVDEDIIDVDDDSAIAEMDCGQPQLKRPFELLIAAAMERNPTQFQLPNELTCTTALPGTSKRRRKEETTGKNVKKAQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCRVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRKGLKVPDAIKSQYRLPPPLLAPAAIRDGELICNGIPEEPLQKHLLNTEHLASQTEQQEWLCSVVALQCSILKHLSAKQMTSLWDSEQTEKADIKPVIVADGTLANPYQAADKAPTPSLYSMSSCTSGITTQNSLSSSQSQQTLSQEDVNCSSCLDKSKKVSSCGTSNGPTASDVKVNGPHFYGVSSEPSAQLTDSQRLIGAGNTIPVLSHRQTWPRPLTPPATCGLLNHTIGTIVKTENVGGPVSCAQRGSVPVTSMPTSISSSCASLETTSTLQRKNVQTQIGPPLSADLRSMGSPLTATRALTPPQAAGDGISAVGSANRFCSPAPPSDGKVSPSTLSIGSALTLPSSLTSNSAAMLDLTSSLKAFMDGEIEINMLDEQLIKFLALQRIHQLFPSKAQSLASSVSAHQQSPVANHIEAQRKEVQARAVFYPLMGLGGAVNMCYRTLYIGTGADMDVCLTSYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKMAPTPPSSIVAKVQSVIKRHKSRKQEEEPHGEAAVMNSQAQGQHRKPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDTALVQDMDLEEKLSLKPHQVPVLRSNSVP", "length": 951, "header": "tr|A0A8V1ANB0-1|A0A1D5PLW9_CHICK Computationally mapped isoform of PHD finger protein 12 OS=Gallus gallus OX=9031 GN=PHF12 PE=4 SV=1 CANONICAL=A0A1D5PLW9-1" }, "locus": { "chromosome": "19", "start_pos": 6394256, "end_pos": 6367940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071779.1", "url": "https://www.ensembl.org/id/ENSGALT00010071779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044469.1", "url": "https://www.ensembl.org/id/ENSGALP00010044469.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 542, "start_aa": "Thr", "end_pos": 542, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr542", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 885, "start_aa": "Thr", "end_pos": 885, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr885", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417580", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B7A1-1", "protein_name": "PHD finger protein 12", "gene_name": "PHF12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSGKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSNASTETPTSEQNDVDEDIIDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRMLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQTHLVNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSITTSLQTADKAPPPSHYPLSCPSGLSTQNSLSCSPPHQPPTLEDISCSSCAEKSKKAPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLPNHTVGIIVKTENATGPSSCPQRSVGLVPSLPPSVPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAAGDGILATGANQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQASPGGVGAHPLASGGHHMEVQRREVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGEAGLLQDGVLAEKLSLKPHQGPVLRSNSVP", "length": 1004 }, "evidence": [ { "id": "A0A1D5PLW9", "url": "https://omabrowser.org/oma/group/A0A1D5PLW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RNA4-1", "protein_name": "PHD finger protein 12", "gene_name": "PHF12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKADEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSGKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSNASTETPTSEQNDVDEDIIDVDEEPVAAEPDCVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQTHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSITNSLQTADKAPTPSHYPLSCPSGLSTQNSLSCSPPHQPPTLEDISCSSCAEKSKKAPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAGDGILATGANQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQASPGSVGAHPLASGGHHTEVQRREVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQGPVLRSNSVP", "length": 1003 }, "evidence": [ { "id": "A0A1D5PLW9", "url": "https://omabrowser.org/oma/group/A0A1D5PLW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SPL2-1", "protein_name": "PHD finger protein 12", "gene_name": "Phf12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKESRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSSKRTTSPSSDTDLLDRPASKTELKAIAHARILERRASRPGTPTSNASTETPTSEHNDVDEDIVDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKRTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICSGVPEESQTHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSPWDSEQTEKADIKPVIVTDSSITTSLQTADKAPLPSHYPLSCPSAVSTQNSLGCSPPHQPPTLEDISCSSCVEKSKKAPCGTANGPVNTEIKANGPHLYSSPTDSTDPRRLPGANTPLPGLTHRQGWPRPLTPPSAGGLQNHVGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLHRKTVQSQIGPSSTESRPLGSPPNATRVLTPPQAAGDSILATGANQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRVHQLFPSRVQASPGNVGTHPLASGGHHPEVQRKEVQARAVFCPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQGPVLRSNSVP", "length": 1003 }, "evidence": [ { "id": "A0A1D5PLW9", "url": "https://omabrowser.org/oma/group/A0A1D5PLW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QT6-1", "protein_name": "PHD finger protein 12", "gene_name": "PHF12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSGKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSSASTETPTSEQNDVDEDIIDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSVTTSLQTADKTPTPSHYPLSCPSGISTQNSLSCSPPHQSPALEDIGCSSCAEKSKKTPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAAGDGILATTANQRFSSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQPSPGSVGTHQLASGGHHIEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQGPVLRSNSVP", "length": 1004 }, "evidence": [ { "id": "A0A1D5PLW9", "url": "https://omabrowser.org/oma/group/A0A1D5PLW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W410-1", "protein_name": "PHD finger protein 12", "gene_name": "PF1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKLDQDPNASLSIMEQIKQLIRPPPNEDEKMMQRSTNTKHPYYRRPGRGHNHDYCDACEEGGNLLCCDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSCRMSKLSQPPASSSKASSVERVPSAGSGSRANTPSSGDLESIPLKIRNLRKRSNSERNSTEKLLAKMPMSIQRALDPNKKPTPLDDVIRAATMMNPQQFSLPPELELHTQFPGNGKVQPVQQTHPPSGNGGNRRCAGNQRRNSKPFELDAQGLVPLPAKTCFYCTRSCKRAPLISCDYCPLYFHQDCLDPPLTALPAGLWMCPNHAENFIDANMTNSISATERVRLWNRFHQPLDHENVKLEFFRRVNTRNPPFRTKRNLRARAHIEVPAIVRYHYDHPPPLLPSMRQTLRYDRVKRRNNLPTEVEEISRESVTESLLKDLEALRTAHAKFREIQREFGTLETAIDGDSDSDPSPEEKRTETNTPADKVNGEVDTENPNTESNAQASEQPSVVKVESKTSLEVEASFEEDEEDSKKSTGIIDADLLHLDVDIIKKLAHQRLQQLVEEHPEIVTQYKNRTAARRLRQLASVDGTHVAGETAALQGQLAPEDMNRFSLLFTSETSSILAQKNGNAADEDPATALHPALATAAAIAAADAAAESYAPRARSDTEKAYELASRLELKLLQCKVQARAVITPLGDMLEDSRWFSSLGLDHSIFMRYRTLYIGYGGHYSPSTTLAQTETVDLSAIGYCCRISPQHAIIFYDEFSKSYELINYSEFGTEVNGQLYACDVTERMTTHAGKPMRPDDAELKKRVDEMLDKRRNINRQFETKKIDKERLAPIVKPACRCMNAGPVPMVDGAWEGSAVLAHGSLLRFGCLSFVFVVPSVDLLQAQARSKRS", "length": 878 }, "evidence": [ { "id": "A0A1D5PLW9", "url": "https://omabrowser.org/oma/group/A0A1D5PLW9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PLW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1009, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PLW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLW9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 487, 542, 885 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 861, "end_pos": 863 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PM71-1", "uniprot_ac": "A0A1D5PM71", "uniprot_id": "A0A1D5PM71_CHICK", "mass": { "chemical_mass": 7587.0, "monoisotopic_mass": 7587.0 }, "refseq": { "ac": "NP_001289129", "name": "adipogenesis regulatory factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289129" }, "gene_names": [ { "name": "ADIRF", "type": "recommended", "evidence": [ { "id": "A0A1D5PM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71" } ] }, { "name": "ADIRF", "type": "synonym", "evidence": [ { "id": "NP_001289129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289129" } ] } ], "protein_names": [ { "name": "Adiposis regulatory factor", "type": "synonym", "evidence": [ { "id": "A0A1D5PM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71/entry#names_and_taxonomy" } ] }, { "name": "adipogenesis regulatory factor", "type": "synonym", "evidence": [ { "id": "NP_001289129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289129" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01142225.1, HAEK01040393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289129" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM71", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADIRF", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71", "locus": {} } ], "crossref": [ { "id": "A0A1D5PM71", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PM71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030461", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030461", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768752", "url": "https://www.ncbi.nlm.nih.gov/gene/768752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR034450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768752", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XDQATET", "url": "https://omabrowser.org/oma/group/XDQATET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PM71", "url": "https://www.orthodb.org/?gene=A0A1D5PM71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39227:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39227:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001289129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289129", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PM71", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGRGFQGLKEQAEGAAKDAASALGQATQDAVSQITDAGQKAVDKACKTAQDGAEKAAGQAAEALSGFGKKCGFKK", "length": 76, "header": "tr|A0A1D5PM71-1|A0A1D5PM71_CHICK Isoform 1 of Adiposis regulatory factor OS=Gallus gallus OX=9031 GN=ADIRF PE=4 SV=1 CANONICAL=A0A1D5PM71-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71/entry", "sequence": { "sequence": "MLGRGFQGLKEQAEGAAKDAASALGQATQDAVSQITDAGQKAVDKACKTAQDGAEKAAGQAAEALSGFGKKCGFKK", "length": 76, "header": "tr|A0A1D5PM71-1|A0A1D5PM71_CHICK Isoform 1 of Adiposis regulatory factor OS=Gallus gallus OX=9031 GN=ADIRF PE=4 SV=1 CANONICAL=A0A1D5PM71-1" }, "locus": { "chromosome": "6", "start_pos": 3328762, "end_pos": 3326871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025128.1", "url": "https://www.ensembl.org/id/ENSGALT00010025128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014259.1", "url": "https://www.ensembl.org/id/ENSGALP00010014259.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768752", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q15847-1", "protein_name": "Adipogenesis regulatory factor", "gene_name": "ADIRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKGLQDLKQQVEGTAQEAVSAAGAAAQQVVDQATEAGQKAMDQLAKTTQETIDKTANQASDTFSGIGKKFGLLK", "length": 76 }, "evidence": [ { "id": "A0A1D5PM71", "url": "https://omabrowser.org/oma/group/A0A1D5PM71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM71", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PM71", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PM71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 76, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PM71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PM71" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PML9-1", "uniprot_ac": "A0A1D5PML9", "uniprot_id": "A0A1D5PML9_CHICK", "mass": { "chemical_mass": 192314.0, "monoisotopic_mass": 192314.0 }, "refseq": { "ac": "NP_001254464", "name": "rho guanine nucleotide exchange factor TIAM2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254464" }, "gene_names": [ { "name": "TIAM2", "type": "recommended", "evidence": [ { "id": "A0A1D5PML9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9" } ] }, { "name": "TIAM2", "type": "synonym", "evidence": [ { "id": "NP_001254464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254464" } ] } ], "protein_names": [ { "name": "T-cell lymphoma invasion and metastasis 2", "type": "synonym", "evidence": [ { "id": "A0A1D5PML9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor TIAM2", "type": "synonym", "evidence": [ { "id": "NP_001254464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254464" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA103992290, SAMEA103992323 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On May 31, 2012 this sequence version replaced XP_419687.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001254464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254464" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PML9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIAM2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9", "locus": { "chromosome": "3", "start_pos": 50271672, "end_pos": 50186382, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005307", "url": "https://www.ensembl.org/id/ENSGALG00010005307" } ] } } ], "crossref": [ { "id": "ENSGALG00000036005", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036005", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421648", "url": "https://www.ncbi.nlm.nih.gov/gene/421648", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421648", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421648", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PML9", "url": "https://www.orthodb.org/?gene=A0A1D5PML9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46001:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46001:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001254464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PML9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PML9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNSESQYSLQGSKNHAAASTGSKQKPCSLKIRSIHAKDEKSCSLHGWGHTNSGSNYKSRSLARSCLSHFKSSQPYSARLSDTVVKASKSNVLAKHRTHTSGDYCPGNNAVFLPDNGFHYIGLQAGSNHAAPRDCNGHILKCYGKNESLASTSPSEDRRSPKVLIKTLGKLDGCLRVEFHNSSNSKVPTEESSGPVQLLRYSPTLESKSNNLLDVRRNSSADCSSNHRLSPTDSRLRSSKGSSLSSESSWYDSLWGNAGDISELDGPYLTRSTPDTSIHASFPASDKKSFNQSSSLSSLRDLYKDTNLEGTPPPGIRLSDEYIDTHGSLSNRVSFASDIDVPSRVEQGSPAHYSSYTLPCRKSKPLAEDASKKDTLKSRMRRISDWTGSLSRKKRKLQEPKCKDGSEYFDSRMDNFSTDTLAPSQQSTLLWSPSSSHILSQRSESTNAVSSDALRQNIYENFMRELEMSRTNLENTETSSETEDSSSESLSSLEQLDLLYEKEQGVVRKAGWLFFKPLVTLQKEKKLELVTRRKWKQYWVTLKGCTLLFYETYGRNSMEQSSLPRYALFAEDSIVQSVPEHPKKENVFCLSNSFGDVYLFQATSQTDLENWVTAIHSACASLFAKKLGKEDTVRLLKNQTKSLFQKIDMDSKMKKMAELQLSIVSDPKNRKAIENQIQQWEQNLEKFNMDLFRMRCYLASLQGGELPNPKSLLAAASRPSKLALGRLGIFSVSSFHALICSRDEAALRKRTLSLSQRVRNKKGLFSSLKGLDTLARKGKEKRPSITQQVDEFLNVYCSVPDSIQKENAWETQTYVHFCDGQGVALTLKPDHRVEDVLSLACKMKQLEPRNYGLQLRRLVDENTEYCAPEPYEYIVDQESVYDEIEICPLNVYHIHLTKTENITDFGFAVTAQVDENQHLTHIFVSDVLPDGLAYREGLRVGNEILSINGESVSDLDLRQMELLFSERSVMLTLRMSHCGNQQPLCASWSSDGDISRVPKSLLPPPNQSQLLEEFLDNFRKNTENDFNNVPDVTSSLKRSSTDGTLDQVPHREKTDPPFRSAEQISALCRNFQEVQTSSMEGQKDNQDPPPRPLARHLSDADRLRKVIQELMDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLDFQKVFLETLEDGISSSSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDSAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDNESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVADQSGTEKEVTELSMGELLMHSTVSWLNPFPSLGKARKDLELTVFVFKRAVILVYKENYKLKKKMPTNVRAAHNYGDLDPFKFRWLIPLSALQVRLGNTAGTENSCIWELIHTKSELEGRPETIFQLCSSDCENKTNIVKVIRSILRENFRRHIKCELPLDKTCKDRLIPLKNRVPATAKLASTRSLKVLKNSPSSEWNGDQGKGTFQDSDDCSLSSSTQSSSCNTTESIQEPKTSSPDQHVQSCSSDFSNALVKESDILSDDDDDDYQSLKKGSPTKDIEIQFQRLKISEEPSTDSERDQAAEKEEGDGFKMGEHPKLIRGHFCPVKRKVNSTKRNRGTLTAMQERHQSLDSHSDAANLDLNSILEREFSVQSLTSVVNEDCFYEAVERHGKS", "length": 1705, "header": "tr|A0A1D5PML9-1|A0A1D5PML9_CHICK Isoform 1 of T-cell lymphoma invasion and metastasis 2 OS=Gallus gallus OX=9031 GN=TIAM2 PE=4 SV=1 CANONICAL=A0A1D5PML9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PML9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PML9/entry", "sequence": { "sequence": 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"length": 1705, "header": "tr|A0A1D5PML9-1|A0A1D5PML9_CHICK Isoform 1 of T-cell lymphoma invasion and metastasis 2 OS=Gallus gallus OX=9031 GN=TIAM2 PE=4 SV=1 CANONICAL=A0A1D5PML9-1" }, "locus": { "chromosome": "3", "start_pos": 50271068, "end_pos": 50186388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012581.1", "url": "https://www.ensembl.org/id/ENSGALT00010012581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007145.1", "url": "https://www.ensembl.org/id/ENSGALP00010007145.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421648", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": 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"https://www.ncbi.nlm.nih.gov/protein/XP_040511851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AEBP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0", "locus": { "chromosome": "1", "start_pos": 64645342, "end_pos": 64595432, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013791", "url": "https://www.ensembl.org/id/ENSGALG00010013791" } ] } } ], "crossref": [ { "id": "A0A1D5PMP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PMP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038026", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038026", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418184", "url": "https://www.ncbi.nlm.nih.gov/gene/418184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418184", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418184", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAENICL", "url": "https://omabrowser.org/oma/group/FAENICL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMP0", "url": "https://www.orthodb.org/?gene=A0A1D5PMP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U0J1", "url": "https://www.orthodb.org/?gene=A0A3Q2U0J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46541", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46541", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46541:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46541:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0J1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0J1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARSDMAEPEGLLPGEAAAAAAEEEEEAAAAAAAAGVGSSSSPPSSAAETESLLLLNGEAESMSEPSPESASQAGDGEDEDEEEEEEEEEGGEEEESSLVGSSSTSSGCCSDETRSLSPGGSSEADAKEEPKGPRGGQEGGLGRGGGGGSSSSSVSSGGDEGYGTGGGGGSSGSSSCSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPVMMNGQGVPASSAKSIAYNCCWDHCHACFSSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVASQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWTPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRNSSKGGTYSGILKDHFC", "length": 494, "header": "tr|A0A1D5PMP0-1|A0A1D5PMP0_CHICK Isoform 1 of Zinc finger protein AEBP2 OS=Gallus gallus OX=9031 GN=AEBP2 PE=3 SV=2 CANONICAL=A0A1D5PMP0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0/entry", "sequence": { "sequence": "MAAARSDMAEPEGLLPGEAAAAAAEEEEEAAAAAAAAGVGSSSSPPSSAAETESLLLLNGEAESMSEPSPESASQAGDGEDEDEEEEEEEEEGGEEEESSLVGSSSTSSGCCSDETRSLSPGGSSEADAKEEPKGPRGGQEGGLGRGGGGGSSSSSVSSGGDEGYGTGGGGGSSGSSSCSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPVMMNGQGVPASSAKSIAYNCCWDHCHACFSSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVASQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWTPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRNSSKGGTYSGILKDHFC", "length": 494, "header": "tr|A0A1D5PMP0-1|A0A1D5PMP0_CHICK Isoform 1 of Zinc finger protein AEBP2 OS=Gallus gallus OX=9031 GN=AEBP2 PE=3 SV=2 CANONICAL=A0A1D5PMP0-1" }, "locus": { "chromosome": "1", "start_pos": 64642014, "end_pos": 64595631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033123.1", "url": "https://www.ensembl.org/id/ENSGALT00010033123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019583.1", "url": "https://www.ensembl.org/id/ENSGALP00010019583.1" } ] } }, { "isoform_ac": "A0A3Q2U0J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0J1/entry", "sequence": { "sequence": "MAAARSDMAEPEGLLPGEAAAAAAEEEEEAAAAAAAAGVGSSSSPPSSAAETESLLLLNGEAESMSEPSPESASQAGDGEDEDEEEEEEEEEGGEEEESSLVGSSSTSSGCCSDETRSLSPGGSSEADAKEEPKGPRGGQEGGLGRGGGGGSSSSSVSSGGDEGYGTGGGGGSSGSSSCSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPVMMNGQGVPASSAKSIAYNCCWDHCHACFSSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVASQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWTPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKR", "length": 486, "header": "tr|A0A3Q2U0J1-1|A0A3Q2U0J1_CHICK Computationally mapped isoform of Zinc finger protein AEBP2 OS=Gallus gallus OX=9031 GN=AEBP2 PE=3 SV=1 CANONICAL=A0A1D5PMP0-1" }, "locus": { "chromosome": "1", "start_pos": 64643304, "end_pos": 64595631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033111.1", "url": "https://www.ensembl.org/id/ENSGALT00010033111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019574.1", "url": "https://www.ensembl.org/id/ENSGALP00010019574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418184", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418184", "resource": "KEGG Pathway" }, { "id": "R-GGA-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A054-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "Aebp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAALTDMADLEELSRLSPLSPGSPGPAARGRAEPPEEEEEEEDDEAEAEAVAALLLNGGAGGGAGGGEAETMSEPSPESASQAGGDEDEDDEDDEDEGSSSGGAEEESSAESLVGSSSGGCSGDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGGPGGPGNGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTLMDIDSTISSGRSTPAMMNGQGSTAASSKHIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEESGKIKLLLHWMPEDILPDVWVNESERHQLRTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRGPWLGFQHLHDDSVTSVTSVQGIRCPLLTVMGNRHMCKINLKK", "length": 538 }, "evidence": [ { "id": "A0A1D5PMP0", "url": "https://omabrowser.org/oma/group/A0A1D5PMP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A4FV57-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAALTDMADLEELSRLSPLPPGSPGPAARGRAEPPEEEEEEDEEEEAEAEAVAALLLNGGGGGGGVGGGEAETMSEPSPESASQAGEDDDEEEDDDEEEEDESSSGGGEEESSAESLVGSSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCWDQCQACFTSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ", "length": 511 }, "evidence": [ { "id": "A0A1D5PMP0", "url": "https://omabrowser.org/oma/group/A0A1D5PMP0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ", "length": 517 }, "evidence": [ { "id": "A0A1D5PMP0", "url": "https://omabrowser.org/oma/group/A0A1D5PMP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z248-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "Aebp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALADMADLEELSRLSPLSPGSPGPAARGRAEPPEEEEEEDDEEAEAEAVAALLLNGGAGGGAGGGEAETMSEPSPESASQAGGDEDEDEEDDEDEGSSSGGAEEESSAESLVGSSSGGCSGDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGGPGGPGSSGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTLMDIDSTISSGRSTPAMMNGQGSTTASSKHIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEESGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRFDILNFPR", "length": 504 }, "evidence": [ { "id": "A0A1D5PMP0", "url": "https://omabrowser.org/oma/group/A0A1D5PMP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMP0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PMP0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 494, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PMP0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PMP0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMP0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 274, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A1D5PN95", "uniprot_id": "A0A1D5PN95_CHICK", "mass": { "chemical_mass": 65995.0, "monoisotopic_mass": 65995.0 }, "refseq": { "ac": "XP_046758903", "name": "breast carcinoma-amplified sequence 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758903" }, "gene_names": [ { "name": "BCAS1", "type": "recommended", "evidence": [ { "id": "A0A1D5PN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95" } ] }, { "name": "BCAS1", "type": "synonym", "evidence": [ { "id": "XP_046758903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758903" } ] } ], "protein_names": [ { "name": "Brain enriched myelin associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PN95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95/entry#names_and_taxonomy" } ] }, { "name": "breast carcinoma-amplified sequence 1", "type": "synonym", "evidence": [ { "id": "XP_046758903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758903" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758903" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PN95", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCAS1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95", "locus": { "chromosome": "20", "start_pos": 12761623, "end_pos": 12722297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015485", "url": "https://www.ensembl.org/id/ENSGALG00010015485" } ] } } ], "crossref": [ { "id": "A0A1D5PN95", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PN95", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007796", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007796", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419338", "url": "https://www.ncbi.nlm.nih.gov/gene/419338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SASVPHH", "url": "https://omabrowser.org/oma/group/SASVPHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PN95", "url": "https://www.orthodb.org/?gene=A0A1D5PN95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UND6", "url": "https://www.orthodb.org/?gene=A0A3Q2UND6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKU4", "url": "https://www.orthodb.org/?gene=A0A8V0YKU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKV4", "url": "https://www.orthodb.org/?gene=A0A8V0YKV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS82", "url": "https://www.orthodb.org/?gene=A0A8V0YS82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSH8", "url": "https://www.orthodb.org/?gene=A0A8V0YSH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYZ4", "url": "https://www.orthodb.org/?gene=A0A8V0YYZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NP35", "url": "https://www.orthodb.org/?gene=F1NP35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15016:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15016:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PN95", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PN95-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UND6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UND6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UND6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP35", "url": "https://www.uniprot.org/uniprotkb/F1NP35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP35-1", "url": "https://www.uniprot.org/uniprotkb/F1NP35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLSGRGSGGPTPLAEEIAPSPDHHTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 629, "header": "tr|A0A1D5PN95-1|A0A1D5PN95_CHICK Isoform 1 of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=2 CANONICAL=A0A1D5PN95-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PN95-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95/entry", "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLSGRGSGGPTPLAEEIAPSPDHHTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 629, "header": "tr|A0A1D5PN95-1|A0A1D5PN95_CHICK Isoform 1 of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=2 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12726395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037181.1", "url": "https://www.ensembl.org/id/ENSGALT00010037181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021583.1", "url": "https://www.ensembl.org/id/ENSGALP00010021583.1" } ] } }, { "isoform_ac": "A0A3Q2UND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UND6/entry", "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLGSKRMSDAEVQTDPVSILPAGKSK", "length": 517, "header": "tr|A0A3Q2UND6-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12726395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037199.1", "url": "https://www.ensembl.org/id/ENSGALT00010037199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021594.1", "url": "https://www.ensembl.org/id/ENSGALP00010021594.1" } ] } }, { "isoform_ac": "A0A8V0YKU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU4/entry", "sequence": { "sequence": "MLNCSDDVGWRNMVGIKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 380, "header": "tr|A0A8V0YKU4-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12737598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037156.1", "url": "https://www.ensembl.org/id/ENSGALT00010037156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021570.1", "url": "https://www.ensembl.org/id/ENSGALP00010021570.1" } ] } }, { "isoform_ac": "A0A8V0YKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV4/entry", "sequence": { "sequence": "MVEEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLSGRGSGGPTPLAEEIAPSPDHHTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 388, "header": "tr|A0A8V0YKV4-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12726649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037175.1", "url": "https://www.ensembl.org/id/ENSGALT00010037175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021580.1", "url": "https://www.ensembl.org/id/ENSGALP00010021580.1" } ] } }, { "isoform_ac": "A0A8V0YS82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS82/entry", "sequence": { "sequence": "MSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 317, "header": "tr|A0A8V0YS82-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12737890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037161.1", "url": "https://www.ensembl.org/id/ENSGALT00010037161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021572.1", "url": "https://www.ensembl.org/id/ENSGALP00010021572.1" } ] } }, { "isoform_ac": "A0A8V0YSH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH8/entry", "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLSGRGSGGPTPLAEEIAPSPDHHGSKRMSDAEVQTDPVSILPAGKSK", "length": 493, "header": "tr|A0A8V0YSH8-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12726395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037193.1", "url": "https://www.ensembl.org/id/ENSGALT00010037193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021589.1", "url": "https://www.ensembl.org/id/ENSGALP00010021589.1" } ] } }, { "isoform_ac": "A0A8V0YYZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ4/entry", "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLSGRGSGGPTPLAEEIAPSPDHHTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLVRYVDPVFLSYFLTNFNSQSASC", "length": 582, "header": "tr|A0A8V0YYZ4-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=1 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12755871, "end_pos": 12726395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037167.1", "url": "https://www.ensembl.org/id/ENSGALT00010037167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021576.1", "url": "https://www.ensembl.org/id/ENSGALP00010021576.1" } ] } }, { "isoform_ac": "F1NP35-1", "url": "https://www.uniprot.org/uniprotkb/F1NP35/entry", "sequence": { "sequence": "MGNTGSAPEEVEEDCTCPVISYQALPESPATVKNGSAVFVQAHSPAMNGGVDVKESVAQDNAAASSPETKERSAAAAGREAAGSAASRALPSAKLRSVFAFSWSVPGRTEDPASDSSVGLVKLDVSSEAHSANKAPSDSAASPAAAAPQPSTHKEPDQAPPAAAPQLGSPTVPGTPKGEDAAVLKPKQVNFFDKIFKLEKGKERSQAQTGAQEGGQPSDAPDGHSTAQEAAAPQSASNGILLEKEIDDCNQRDLRQDSAGVSGLTAGQPEKAEVKQDSSQPAAAVDNNSVMSFLKTLVSPSKAEGRSEPEDKGSKAEQGRGGQPAAKTAESPTKGAKKKKAESPKLGHSTFSKLFRHKAAKETQQTANTKTTEQQPVTSVKSDKNVPSAQEPQTAKQNTKAPEPTAQQQAAATEAPREAAKEKGSSTPMPLSKLFWKKNALEEAEVAHNEKADASLEAVTPDKDERSSEVLEVKPRKEESKTPKANLRKFFKLTLNSTERPVATAESEPVSQKSKESSKDKKPPAELSKQKGSKQETREQPDCREQHAAETDSIQSGGDAAKEPTSFKRMEKRQSFGGFFKGLGSKRMSDAEVQTDPVSILPAGKSK", "length": 607, "header": "tr|F1NP35-1|A0A1D5PN95_CHICK Computationally mapped isoform of Brain enriched myelin associated protein 1 OS=Gallus gallus OX=9031 GN=BCAS1 PE=1 SV=4 CANONICAL=A0A1D5PN95-1" }, "locus": { "chromosome": "20", "start_pos": 12760760, "end_pos": 12726395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037187.1", "url": "https://www.ensembl.org/id/ENSGALT00010037187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021585.1", "url": "https://www.ensembl.org/id/ENSGALP00010021585.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 502, "start_aa": "Thr", "end_pos": 502, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr502", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LQB6-1", "protein_name": "Brain enriched myelin associated protein 1", "gene_name": "BCAS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNQMSVPQRVEDQENDPEADTHKVTSGDACGQNGLPVITSARTVQLYDEVDLGISMQEDNVAASSPKTMETSAAAEANGESLGKDAKPQAPAAKSRFFLTLSRPVPGRTGDQATDSSSGSVRLDVSSDKAPGNKDPSEPMALPVAAAPGHGPDKTPGQTPAQAEGLPATPGPEHPPSESGAAAAAKPKDSSFFDKLFKLDKGRDKAPVDLPLEAESTEHPHPAAEAPGLSKQSEDGPAERDLVDGKGKAGQEVPTVSCSVPGDPEQLEIAKEDAQAENSSIMSFFKTLVSPHKAETKKDPEDTASKGESVSDGQAGQKTSEVQAKGAKKKHLHSPRLGLAFRKFFRHKGEEKSAAPSANLKSDKANVTLQEPQGAAKNSTPTETAKEKGGPSSLPLGKLFWKKSVKEDSVPTGAEENVVCESPVEAVKSEEVESALQTVDLGEEGERTPDPAEEAPRREERRAPRPSLMALLRQMSVKGDGGITHSEEINEKDSSYQTSDPTEKVVAPPQPEAAAAAAGQKGKEGPSKDKKAAAETNKQKGNRQEAKEPALGVEPAAAEANSLPNGDKPQKRPEKRRQSLGGFFKGLGPKRMLDAQVQTDPVSIGPAGKSK", "length": 612 }, "evidence": [ { "id": "A0A1D5PN95", "url": "https://omabrowser.org/oma/group/A0A1D5PN95/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75363-1", "protein_name": "Breast carcinoma-amplified sequence 1", "gene_name": "BCAS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNQMSVPQRVEDQENEPEAETYQDNASALNGVPVVVSTHTVQHLEEVDLGISVKTDNVATSSPETTEISAVADANGKNLGKEAKPEAPAAKSRFFLMLSRPVPGRTGDQAADSSLGSVKLDVSSNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAGGEAPSKPKDSSFFDKFFKLDKGQEKVPGDSQQEAKRAEHQDKVDEVPGLSGQSDDVPAGKDIVDGKEKEGQELGTADCSVPGDPEGLETAKDDSQAAAIAENNNSIMSFFKTLVSPNKAETKKDPEDTGAEKSPTTSADLKSDKANFTSQETQGAGKNSKGCNPSGHTQSVTTPEPAKEGTKEKSGPTSLPLGKLFWKKSVKEDSVPTGAEENVVCESPVEIIKSKEVESALQTVDLNEGDAAPEPTEAKLKREESKPRTSLMAFLRQMSVKGDGGITHSEEINGKDSSCQTSDSTEKTITPPEPEPTGAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQNGDKLQKRPEKRQQSLGGFFKGLGPKRMLDAQVQTDPVSIGPVGKSK", "length": 584 }, "evidence": [ { "id": "A0A1D5PN95", "url": "https://omabrowser.org/oma/group/A0A1D5PN95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZB98-1", "protein_name": "Breast carcinoma-amplified sequence 1 homolog", "gene_name": "Bcas1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNQMSVPLRPGDQEHDPEADTYKVTSDNECVQNGIPVVVSTRVIQHYEEVDLGINSLKDNVPASSPETMEAHAVADASGKNLGKGSKPKAPAARSHFFLTLSRPVPGRPGDQGTDSSAASGRLDVSPGTAPENKDPSEHGALPVAAAPGPAPDKTPGCTEAKQQTLPATSPLAPSPPESQAEAPSRPKDFSFLNRLFKLDKGRESAPADSPPEEGKGSKSQERAIEAPAVPGNPHGVSAGKDIVDSEERKQEVDTLSYSVPADPEVLGTTKEDPQVVDATENSNSIMSFFKTLVSPNKTETKKDPEDTDAENSPTTPANLKSDKADLTPQETQGTAKSSKGSSQPGQAPSAGTSDTAREGGKEKAGPTSLPLGKLFWKKSVKEDSLSTGAEENAVCEPPVETVRLEEVESTLQTVDLTEKETQTEPTDVKVKEESKPRRTPLMAFLRQMSVRGSEGITRSEESNGKDSSCQTSNSTEKTPSPPEPEPAGTAQKNKETSSKDKKSVDKKSAAESNKQKNGKPEAREPAPCVQQPTVEVNALQTGDKTPKRSEKRRQSLGGFLKGLGPKRMLDAQVQTDPVSIGPVGKSK", "length": 589 }, "evidence": [ { "id": "A0A1D5PN95", "url": "https://omabrowser.org/oma/group/A0A1D5PN95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80YN3-1", "protein_name": "Breast carcinoma-amplified sequence 1 homolog", "gene_name": "Bcas1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNQMSVPLRPGDQEHDPGADTCKVTSDNECVQNGNPVVLSTRVIQHYEEVDLGISSSKDNVATSSPKTMEAQAVGDASGKNLGKEAKTKAPAARSHFFLTLSRPVPGRPGDQGTDSSAASGRFDVSPSAAPENKDPSEHGALPVAAAPGQAPDKTPGCPEAKQQTLPATGPLAPSPPESQAEAPAQDKDFGFLNRFFKLDKGRESAPVNSQPKEAKGSEDPEQATEAPAVPGNPHGVSAGEDIVDSEQRGQDVDTLSYSVPGDPEVPGTTKEDPQVVDTTENSSSIMSFFKTLVSPNKTETKKDPEDTKATKADSVCDGHAAGQKMSETQAKSKKKRLDSPRLGLSFRKLFRHKDTENSPTTSANLKSDKANFTPQETRGKTKATKSCSPPPPPPEPTSEGRDSGKEKAGPTSLPLGKLFWKKSVKEDTLSTGAEENAVCESPVETVRLEEVESSLQTVDLSEETQPEPTDVKVKEESKPRKTPLMAFLRQMSVRSSEGIPRSEESNVKDSSCQTSNSVEKTPSPPEPEPAGTAQKNKETSSSKDKKSVDKKSATENSKQKNGKQEVREPAPCVQPPTVEANAMQTGDKTPKKSEKRRQSLGGFLKGLGPKRMSDAQVQTDPVSIGPVGKSK", "length": 633 }, "evidence": [ { "id": "A0A1D5PN95", "url": "https://omabrowser.org/oma/group/A0A1D5PN95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PN95", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of myelin sheath", "id": "GO:0019911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019911", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PN95", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PN95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 629, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PN95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PN95" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 502 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PNH9-1", "uniprot_ac": "A0A1D5PNH9", "uniprot_id": "A0A1D5PNH9_CHICK", "mass": { "chemical_mass": 135451.0, "monoisotopic_mass": 135451.0 }, "refseq": { "ac": "XP_015142674", "name": "PR domain-containing protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142674" }, "gene_names": [ { "name": "PRDM11", "type": "recommended", "evidence": [ { "id": "A0A1D5PNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ] }, { "name": "PRDM11", "type": "synonym", "evidence": [ { "id": "XP_015142674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142674" } ] } ], "protein_names": [ { "name": "PR domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A1D5PNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9/entry#names_and_taxonomy" } ] }, { "name": "PR domain-containing protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142674" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142674" } ] }, { "annotation": "May be involved in transcription regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9#function" }, { "database": "UniProtKB", "id": "ARBA00055438", "url": "https://www.uniprot.org/uniprotkb/ARBA00055438#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK23#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRDM11", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9", "locus": { "chromosome": "5", "start_pos": 21842817, "end_pos": 21802425, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021738", "url": "https://www.ensembl.org/id/ENSGALG00010021738" } ] } } ], "crossref": [ { "id": "A0A1D5PNH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008053", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008053", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423174", "url": "https://www.ncbi.nlm.nih.gov/gene/423174", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CKNNRSR", "url": "https://omabrowser.org/oma/group/CKNNRSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNH9", "url": "https://www.orthodb.org/?gene=A0A1D5PNH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK23", "url": "https://www.orthodb.org/?gene=A0A8V0ZK23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23098:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23098:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46880:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46880:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPCSGRLDPQSMDVEPKKLKGKRDLIMTKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWLIVDKNNRYKSIDGTDETKANWMRYVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTTGDKKLQKEKSEKNADNQEDTRAPLHFTTLKQGKSPYKRSYDEGESHPQTKKKKIDLIFKDVLEASLESAKFEEKQLATSTPLSTRATSKYQAEEIFERCSSAMQHGSLNLSRNRSEEEWKAPHGSSFSSAKEVGVLEDEEEEPLSLKADSPTELSLASAEGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPPVLPPQVPELQEFSDPTASESIISVPTIMEDDDQEVDSADESVSNEMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAFSSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKWIIGEQNVLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTQGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNKIVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSVDHGSEFYPDI", "length": 1184, "header": "tr|A0A1D5PNH9-1|A0A1D5PNH9_CHICK Isoform 1 of PR domain-containing protein 11 OS=Gallus gallus OX=9031 GN=PRDM11 PE=4 SV=2 CANONICAL=A0A1D5PNH9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9/entry", "sequence": { "sequence": "MSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPCSGRLDPQSMDVEPKKLKGKRDLIMTKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWLIVDKNNRYKSIDGTDETKANWMRYVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTTGDKKLQKEKSEKNADNQEDTRAPLHFTTLKQGKSPYKRSYDEGESHPQTKKKKIDLIFKDVLEASLESAKFEEKQLATSTPLSTRATSKYQAEEIFERCSSAMQHGSLNLSRNRSEEEWKAPHGSSFSSAKEVGVLEDEEEEPLSLKADSPTELSLASAEGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPPVLPPQVPELQEFSDPTASESIISVPTIMEDDDQEVDSADESVSNEMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAFSSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKWIIGEQNVLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTQGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNKIVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSVDHGSEFYPDI", "length": 1184, "header": "tr|A0A1D5PNH9-1|A0A1D5PNH9_CHICK Isoform 1 of PR domain-containing protein 11 OS=Gallus gallus OX=9031 GN=PRDM11 PE=4 SV=2 CANONICAL=A0A1D5PNH9-1" }, "locus": { "chromosome": "5", "start_pos": 21841813, "end_pos": 21817055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052833.1", "url": "https://www.ensembl.org/id/ENSGALT00010052833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031739.1", "url": "https://www.ensembl.org/id/ENSGALP00010031739.1" } ] } }, { "isoform_ac": "A0A8V0ZK23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK23/entry", "sequence": { "sequence": "MSCVVRRGWIPIWLFHMQECPNLGNVPVKCKIKALFWSLIQADKSPWLLTNNYKRGSDEGGILEDRNSQNMSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPCSGRLDPQSMDVEPKKLKGKRDLIMTKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWLIVDKNNRYKSIDGTDETKANWMRYVIISREEREQNLMAFQHSERIYFRACRDIRPGEKLRVWYSEDYMKRLHSMSQETINRNLTTGDKKLQKEKSEKNADNQEDTRAPLHFTTLKQGKSPYKRSYDEGESHPQTKKKKIDLIFKDVLEASLESAKFEEKQLATSTPLSTRATSKYQAEEIFERCSSAMQHGSLNLSRNRSEEEWKAPHGSSFSSAKEVGVLEDEEEEPLSLKADSPTELSLASAEGNSHEIPTTSFCPNCIRLKKKIRELQAELDMLRSGKLPEPPVLPPQVPELQEFSDPTASESIISVPTIMEDDDQEVDSADESVSNEMIAATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYYDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPFLSIILDGQSDDVLADTVAVYVQYTSSDGPPATEFLSLQELGFSTTDSYLQALDRAFSSLGIRLQDEKPTIGLGVDGANITASLRANLFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRVTASTLCEETEFLGDIRAVKWIIGEQNVLNALIKDYLEVVAHLKDVSGQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRTFVKACQVFDLAAWPRSTDELMSYGKEDMVQIFEHLETVPSFSREVCREGMDTQGSLLMEWRELKVDYYTKNGFKDLLSHICKYKQRFPLLNKIVQILKVLPTSSACCEKGRNALQRVRKNNRSRLTLEQLSDLLTIAVNGPPIANFDCKRALDSWFEEKSGNSYALSAEMLSRMSSLDQKPMLQSVDHGSEFYPDI", "length": 1254, "header": "tr|A0A8V0ZK23-1|A0A8V0ZK23_CHICK Computationally mapped isoform of PR domain-containing protein 11 OS=Gallus gallus OX=9031 GN=PRDM11 PE=4 SV=1 CANONICAL=A0A1D5PNH9-1" }, "locus": { "chromosome": "5", "start_pos": 21841813, "end_pos": 21812771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052832.1", "url": "https://www.ensembl.org/id/ENSGALT00010052832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031738.1", "url": "https://www.ensembl.org/id/ENSGALP00010031738.1" } ] } }, { "isoform_ac": "A0A8V0ZLY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY8/entry", "sequence": { "sequence": "MSENLKDCLNQTQASLGEMVTIKTEACSPHRDQEYGQPCSGRLDPQSMDVEPKKLKGKRDLIMTKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPPGIEVVKEPSGENDVRCMNEVIPKGHIFGPYEGQISSQDKSAGFFSWLIVDKNNRYKSIDGTDETKANWMRNMAERKRKPKFSKEELDILVTEVTRNEAMLFGRQTVRLSHADRDKIWEDIARQITSVSQVPRSVKDIKHRWDDMKRRTKDKLAFMQRSLSSPSSKGRPSAIVLTAHERAIESTLHSSHHVHSFRRADLDVVDSPSTSSDEDEEMPGTSQEHHSSSLQRASVEISHLSRPSFLHTSSSSEHSEAISQRQELHRPSPRTSSSCRSPHPRTRSPPLSSFDRQLLHSHLQQTDLFRQFCQELVAIHRDMAESMHVIGQKMTDLTSQVGQMCQTLSEIRDGVQSFHRTQSPSVTWGPLLQAACSKPPPEPSAESNQLPAKQTAPARTTRSRKRKHHI", "length": 516, "header": "tr|A0A8V0ZLY8-1|A0A8V0ZLY8_CHICK Computationally mapped isoform of PR/SET domain 11 OS=Gallus gallus OX=9031 GN=PRDM11 PE=4 SV=1 CANONICAL=A0A1D5PNH9-1" }, "locus": { "chromosome": "5", "start_pos": 21828997, "end_pos": 21817055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052828.1", "url": "https://www.ensembl.org/id/ENSGALT00010052828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031734.1", "url": "https://www.ensembl.org/id/ENSGALP00010031734.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2AGX3-1", "protein_name": "PR domain-containing protein 11", "gene_name": "Prdm11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTENMKECLAHTKAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRLEPSSMEVEPKKLKGKRDLIVTKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDAGGESDVRCINEVIPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKAEQALENPEDLRGPTQFPVLKQGRSPYKRSFDEGDIHPQAKKKKIDLIFKDVLEASLESGNVEARQLALSTSLVIRKVPKYQDDDYGRAALTQGICRTPGEGDWKVPQRVAKELGPLEDEEEEPTSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPSLLPPQVLELPEFSDPAGKFLRMRLLLKGRVCSATRAHCVEGGPERSALSQPPARRPEECNSAEAAPSWGGSPVPQVTEAGWLEDRGREGIACANLYILLVNKICPICRRAVCCVLDLVFSLGGGAHCCLP", "length": 565 }, "evidence": [ { "id": "A0A1D5PNH9", "url": "https://omabrowser.org/oma/group/A0A1D5PNH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A985-1", "protein_name": "PR domain-containing protein 11", "gene_name": "Prdm11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQLSSTTPRKYPGRKVGAARSSSAASPSPWGARRGRASSRAGPARGTRGSARPGSGPLNWGVRVCPKRRFLPFSMSFPVLIRWWSKQGRRAAASRRRAAAGAETLPGRGPRARPPRPAASRRPGPGPARRPAWEPAKDRMTENMKECLAHTKAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRLEPSSMEVEPKKLKGKRDLIVTKSFQQVDFWFCESCQEYFVDECPTHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKEVGGESDVRCINEVVPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKAEQALDNPEDLRGPSHFPVLKQGRSPYKRSFDEGDLHPQAKKKKIDLIFKDVLEASLESANAEGRQLALSTSLVIRKVPKYQDDDYGRAALTQGICRTPGEGDWKVPQKVAKELGPLEDEEEEHTSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKVPEPPILPQQVLELPEFSDPAASESMVSCPAIMEDDDQEVDSADESVSNDVMTATDEPSKLSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAFAALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRWIIGEQNVLNALIKDYLEVVAHLKDVSSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRVFVKACQVFDLAAWPRNNEELLSFGKEDMVQIFDHLEAIPAFSRDVCREGMDPRGSLLMEWRDLKADYYTKNGFKDLISHICKYKQRFPLLNKIIQVLKVLPTSTACCEKGRSALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIASFDAKRALDSWFEEKSGNSYTLSAEVLSRMSALEQKPMLQAVDHGSEFYPDM", "length": 1312 }, "evidence": [ { "id": "A0A1D5PNH9", "url": "https://omabrowser.org/oma/group/A0A1D5PNH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MES5-1", "protein_name": "PR domain-containing protein 11", "gene_name": "PRDM11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTENMKECLAQTKAAVGEMVTVVKTEVCSPLRDQECGQPCSRRSDPSVMEVEPRKLKGKRDLIMPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKEASGENDVRCINEVIPKGRIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREESEQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQKEKSEQALDNPEDLRGPLQLPVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKRQNDAYGQCAMTMSHGVQNASRTQGDGDWKVPQGASKEAGPLEDEEEEPSSFKADSPAEASLASDPPELPTTSFCPNCIRLKKKVRELQAELDMLKSGTLPEPPTLPAQVLELPEFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDIMTATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAFSALGIRLQDEKPTVGLGIDGANVTASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRWIIGEQNVLNALIKDYLEVVAHLKDVSSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYVFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAMKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRIFVKACQVFDLAAWPRSSDELLSYGKEDMVQIFDHLEAIPTFSRDVCREGLDPRGSLLMEWRELKADYYTKNGFKDLIGHICKYKQRFPLLNKIIQVLKVLPTSTACCEKGRNALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIANFDAKRALDSWFEEKSGNSYALSAEVLSRMSALEQKPVLQTVDHGSEFYPDI", "length": 1177 }, "evidence": [ { "id": "A0A1D5PNH9", "url": "https://omabrowser.org/oma/group/A0A1D5PNH9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NQV5-1", "protein_name": "PR domain-containing protein 11", "gene_name": "PRDM11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKMAEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFSDPAGKLVWMRLLSEGRVRSGLCGG", "length": 511 }, "evidence": [ { "id": "A0A1D5PNH9", "url": "https://omabrowser.org/oma/group/A0A1D5PNH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNH9" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 225, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 1109, "end_pos": 1111 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 742, "end_pos": 744 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PNI0-1", "uniprot_ac": "A0A1D5PNI0", "uniprot_id": "A0A1D5PNI0_CHICK", "mass": { "chemical_mass": 62362.0, "monoisotopic_mass": 62362.0 }, "refseq": { "ac": "XP_418786", "name": "copine-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418786" }, "gene_names": [ { "name": "CPNE4", "type": "recommended", "evidence": [ { "id": "A0A1D5PNI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ] }, { "name": "CPNE4", "type": "synonym", "evidence": [ { "id": "XP_418786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418786" } ] } ], "protein_names": [ { "name": "Copine-4", "type": "recommended", "evidence": [ { "id": "A0A1D5PNI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0/entry#names_and_taxonomy" } ] }, { "name": "Copine IV", "type": "synonym", "evidence": [ { "id": "A0A1D5PNI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0/entry#names_and_taxonomy" } ] }, { "name": "copine-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418786" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_418786.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418786" } ] }, { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H1#function" }, { "database": "UniProtKB", "id": "ARBA00057254", "url": "https://www.uniprot.org/uniprotkb/ARBA00057254#function" }, { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z0#function" }, { "database": "UniProtKB", "id": "A0A8V0Z7G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z7I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I7#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPNE4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0", "locus": { "chromosome": "2", "start_pos": 41818841, "end_pos": 42076542, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018601", "url": "https://www.ensembl.org/id/ENSGALG00010018601" } ] } } ], "crossref": [ { "id": "A0A1D5PNI0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029235", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420687", "url": "https://www.ncbi.nlm.nih.gov/gene/420687", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XVIAEEL", "url": "https://omabrowser.org/oma/group/XVIAEEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNI0", "url": "https://www.orthodb.org/?gene=A0A1D5PNI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Z0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7G2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7H1", "url": "https://www.orthodb.org/?gene=A0A8V0Z7H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7I7", "url": "https://www.orthodb.org/?gene=A0A8V0Z7I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8E6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8H0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZEB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 556, "header": "tr|A0A1D5PNI0-1|A0A1D5PNI0_CHICK Isoform 1 of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=2 CANONICAL=A0A1D5PNI0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0/entry", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 556, "header": "tr|A0A1D5PNI0-1|A0A1D5PNI0_CHICK Isoform 1 of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=2 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 41995792, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045036.1", "url": "https://www.ensembl.org/id/ENSGALT00010045036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026905.1", "url": "https://www.ensembl.org/id/ENSGALP00010026905.1" } ] } }, { "isoform_ac": "A0A8V0Z6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z0/entry", "sequence": { "sequence": "MLANFICEIPCWWRKLDILQGSLHQQSHVSLVHATYFPFHRPAAVVSCVLWVKLSHSCQGKSRGKGMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 622, "header": "tr|A0A8V0Z6Z0-1|A0A8V0Z6Z0_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 42063046, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045051.1", "url": "https://www.ensembl.org/id/ENSGALT00010045051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026915.1", "url": "https://www.ensembl.org/id/ENSGALP00010026915.1" } ] } }, { "isoform_ac": "A0A8V0Z7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7G2/entry", "sequence": { "sequence": "MRMFYTSLFGKGMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 568, "header": "tr|A0A8V0Z7G2-1|A0A8V0Z7G2_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 42003491, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045018.1", "url": "https://www.ensembl.org/id/ENSGALT00010045018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026891.1", "url": "https://www.ensembl.org/id/ENSGALP00010026891.1" } ] } }, { "isoform_ac": "A0A8V0Z7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H1/entry", "sequence": { "sequence": "MKVLWDRSVLLRKIQNDLEALPDVWPGKGMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 585, "header": "tr|A0A8V0Z7H1-1|A0A8V0Z7H1_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 42032791, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045030.1", "url": "https://www.ensembl.org/id/ENSGALT00010045030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026901.1", "url": "https://www.ensembl.org/id/ENSGALP00010026901.1" } ] } }, { "isoform_ac": "A0A8V0Z7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I7/entry", "sequence": { "sequence": "MMTRRVQIQLAGKGMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 570, "header": "tr|A0A8V0Z7I7-1|A0A8V0Z7I7_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 42076473, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045054.1", "url": "https://www.ensembl.org/id/ENSGALT00010045054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026917.1", "url": "https://www.ensembl.org/id/ENSGALP00010026917.1" } ] } }, { "isoform_ac": "A0A8V0Z8E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E6/entry", "sequence": { "sequence": "MDIVRDFYFLYPCSILPSPERLSKTSGEEGLLSEQVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 531, "header": "tr|A0A8V0Z8E6-1|A0A8V0Z8E6_CHICK Computationally mapped isoform of Copine 4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 41975602, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045009.1", "url": "https://www.ensembl.org/id/ENSGALT00010045009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026885.1", "url": "https://www.ensembl.org/id/ENSGALP00010026885.1" } ] } }, { "isoform_ac": "A0A8V0Z8H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H0/entry", "sequence": { "sequence": "MTEKKAGDKWPAEGNSSQGKGMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 577, "header": "tr|A0A8V0Z8H0-1|A0A8V0Z8H0_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 42054430, "end_pos": 41819366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045044.1", "url": "https://www.ensembl.org/id/ENSGALT00010045044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026911.1", "url": "https://www.ensembl.org/id/ENSGALP00010026911.1" } ] } }, { "isoform_ac": "A0A8V0ZEB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB9/entry", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHRDEMAADLHSAVSPGGCFLIDIQIPKFSKTEQSPQSILVACKPFLKFCTRIRPRTCCY", "length": 571, "header": "tr|A0A8V0ZEB9-1|A0A8V0ZEB9_CHICK Computationally mapped isoform of Copine-4 OS=Gallus gallus OX=9031 GN=CPNE4 PE=3 SV=1 CANONICAL=A0A1D5PNI0-1" }, "locus": { "chromosome": "2", "start_pos": 41995792, "end_pos": 41824607, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045027.1", "url": "https://www.ensembl.org/id/ENSGALT00010045027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026898.1", "url": "https://www.ensembl.org/id/ENSGALP00010026898.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MWQ1-1", "protein_name": "Copine-4", "gene_name": "Cpne4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 557 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LVU1-1", "protein_name": "Copine-4", "gene_name": "Cpne4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVEPSNPESMKKRVGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 575 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QJ75-1", "protein_name": "Copine-4", "gene_name": "cpne4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSNIYESAATTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVVLKMQSHGQWFEVDRTEVIRSSISPVFSKVFTVDYYFEEVQRLRFELHDISSNHNGLKEADFLGAMECTLGQIVSQRKLSKALLKQGNTAGKSSITVTAEELSGNDDYVELAFSAKKLDDKDFFSKSDPFLEIFRVNDDGTASLVHRTETIMNNLSPVWKSFKVSLNTLCSGDHDRELKCIVWDWDSNGKHDFIGEFQTTFKEMKSAMDGKQIQWECINPKYQVKKKNYRNSGMVILTLCKIIKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALIAVGEICQDYDSDKMFPAFGFGAQIPPDFKVSHDFAVNFDEDNPECAGVQGVIEAYQNCLPKIQLYGPTNIAPIIQKVANSASEEMHTKEAMEYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGIGSADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKGLSDYESSRAFSP", "length": 553 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54P51-1", "protein_name": "Copine-C", "gene_name": "cpnC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIPSSKPNSRVELRFRCHHLKNLDIVSKSDPQIFISEKRGPGGFQFVDCTEKIKNNLSPEFKKTITLDYYFEEIQTLTFTVMDIDKEITLFGDLDKNDKIGEFTTSLSNILSRPGRKIVADLIHHSKVTGKIEISAEEICQTNHHIFLSAEGIGLDKKDLFSSDPYYKIYKTNPNGEQLLVFQSIVIKSNVNPLWPELHMELEKFNGGDMFRELLIEVYDYDSIGAHDLIGITRTTTDAILRGVIEYPLINPKKTSKSGYKNSGILKFYKVRLEKTHTFLEFLAGGCEISLMTAIDCTGSNGSVNSFSGLHYNDLEKGGSAYARSIASVGSVLSSYDSDGFIDVFGFGGEYQGRTSHCFPFSLDPNVPSAFGVAGVLEMYNRNISKIPFSGPTNFASVIQEAIARASESRLPYQQKYTVLLIITDGEICDMDETIKCLVQASNLPLSVVIVGVGLSSFENMNLLDGDNGCLVDYKGNRAKRDIVQFVPFNKYSGNINALAQETLKEIPGQLLSYFKSIGVPPNPPRTFIPVDILPPPPQ", "length": 539 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BLR2-1", "protein_name": "Copine-4", "gene_name": "Cpne4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 557 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96A23-1", "protein_name": "Copine-4", "gene_name": "CPNE4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP", "length": 557 }, "evidence": [ { "id": "A0A1D5PNI0", "url": "https://omabrowser.org/oma/group/A0A1D5PNI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNI0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PNI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNI0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 131, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001289062" } ] }, { "name": "STMP1", "type": "synonym", "evidence": [ { "id": "NP_001289062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289062" } ] } ], "protein_names": [ { "name": "Short transmembrane mitochondrial protein 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PNN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNN4/entry#names_and_taxonomy" } ] }, { "name": "short transmembrane mitochondrial protein 1", "type": "synonym", "evidence": [ { "id": "NP_001289062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289062" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU246816.1, BU290970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992533, SAMN08016558 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Oct 2, 2014 this sequence version replaced XP_429551.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001289062", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289062" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNN4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C7orf73", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNN4", "locus": { "chromosome": "1", "start_pos": 58441811, "end_pos": 58450241, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010106", "url": "https://www.ensembl.org/id/ENSGALG00010010106" } ] } } ], "crossref": [ { "id": "A0A1D5PNN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNN4", "database": "AlphaFoldDB", 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regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNN4" } ], "pmid": "" }, { "name": "mitochondrial respirasome assembly", "id": "GO:0097250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097250", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PNN4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 49, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PNN4-F1.pdb", "url_external": 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"name": "LOC425347", "type": "synonym", "evidence": [ { "id": "XP_025000368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000368" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PNT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 532", "type": "synonym", "evidence": [ { "id": "XP_025000368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000368" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000368" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC425347", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000035785", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425347", "url": "https://www.ncbi.nlm.nih.gov/gene/425347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IMITINC", "url": "https://omabrowser.org/oma/group/IMITINC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNT1", "url": "https://www.orthodb.org/?gene=A0A1D5PNT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16622", "url": 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"length": 1292, "header": "tr|A0A1D5PNT1-1|A0A1D5PNT1_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC425347 PE=3 SV=2 CANONICAL=A0A1D5PNT1-1" }, "locus": { "chromosome": "W", "start_pos": 3931422, "end_pos": 3885114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029273.1", "url": "https://www.ensembl.org/id/ENSGALT00010029273.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016989.1", "url": "https://www.ensembl.org/id/ENSGALP00010016989.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 352, "start_aa": "Thr", "end_pos": 352, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr352", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNT1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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"n_glycosylation_sequon" }, { "start_pos": 992, "end_pos": 994, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PNT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNT1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 612, "end_pos": 630, "start_aa": "Tyr", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 352 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1229, "end_pos": 1231 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 992, "end_pos": 994 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PNW1-1", "uniprot_ac": "A0A1D5PNW1", "uniprot_id": "A0A1D5PNW1_CHICK", "mass": { "chemical_mass": 55925.0, "monoisotopic_mass": 55925.0 }, "refseq": { "ac": "XP_015128584", "name": "cysteine/serine-rich nuclear protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128584" }, "gene_names": [ { "name": "CSRNP2", "type": "recommended", "evidence": [ { "id": "A0A1D5PNW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ] }, { "name": "CSRNP2", "type": "synonym", "evidence": [ { "id": "XP_015128584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128584" } ] } ], "protein_names": [ { "name": "Cysteine and serine rich nuclear protein 2", "type": "synonym", "evidence": [ { "id": "A0A1D5PNW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1/entry#names_and_taxonomy" } ] }, { "name": "cysteine/serine-rich nuclear protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015128584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128584" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSRNP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1", "locus": { "chromosome": "34", "start_pos": 2332602, "end_pos": 2320459, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023931", "url": "https://www.ensembl.org/id/ENSGALG00010023931" } ] } } ], "crossref": [ { "id": "A0A1D5PNW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032004", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032004", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859835", "url": "https://www.ncbi.nlm.nih.gov/gene/100859835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859835", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFRTDHE", "url": "https://omabrowser.org/oma/group/PFRTDHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNW1", "url": "https://www.orthodb.org/?gene=A0A1D5PNW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13580:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13580:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128584", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPLDTPHHRPHPTGPPPTHGVPELHAIPMDAIASGRLKRKFEDVDVGSPASNSDDEISNSDSADSCDSVNPSSSSGFIPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAPRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESEEAEGLTLEDISDDDIDVENVEVDDYFFLQPLPTKQRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELENKRQGARPGDEELQGSGAAWPPGAQPPETQDFQEFMAENETAVMHLQTAEELERLKAEEDSSGGSGVESVGVCILEEPLAVPEALCPGLAAPILIQAQLPPGSSVLCFADGAEQPAATQPYLNAAPLLYYQVEPRSVLGPKGESGAEECPKDTGTVPAAPTGPCSRAAPAPSKGEGAKGVGQEGAQSCAASLGPSAPREAPGSEQPPQGV", "length": 519, "header": "tr|A0A1D5PNW1-1|A0A1D5PNW1_CHICK Isoform 1 of Cysteine and serine rich nuclear protein 2 OS=Gallus gallus OX=9031 GN=CSRNP2 PE=3 SV=1 CANONICAL=A0A1D5PNW1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1/entry", "sequence": { "sequence": "MGAPLDTPHHRPHPTGPPPTHGVPELHAIPMDAIASGRLKRKFEDVDVGSPASNSDDEISNSDSADSCDSVNPSSSSGFIPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAPRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESEEAEGLTLEDISDDDIDVENVEVDDYFFLQPLPTKQRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELENKRQGARPGDEELQGSGAAWPPGAQPPETQDFQEFMAENETAVMHLQTAEELERLKAEEDSSGGSGVESVGVCILEEPLAVPEALCPGLAAPILIQAQLPPGSSVLCFADGAEQPAATQPYLNAAPLLYYQVEPRSVLGPKGESGAEECPKDTGTVPAAPTGPCSRAAPAPSKGEGAKGVGQEGAQSCAASLGPSAPREAPGSEQPPQGV", "length": 519, "header": "tr|A0A1D5PNW1-1|A0A1D5PNW1_CHICK Isoform 1 of Cysteine and serine rich nuclear protein 2 OS=Gallus gallus OX=9031 GN=CSRNP2 PE=3 SV=1 CANONICAL=A0A1D5PNW1-1" }, "locus": { "chromosome": "34", "start_pos": 2331598, "end_pos": 2326461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058288.1", "url": "https://www.ensembl.org/id/ENSGALT00010058288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035410.1", "url": "https://www.ensembl.org/id/ENSGALP00010035410.1" } ] } }, { "isoform_ac": "A0A8V0ZUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ1/entry", "sequence": { "sequence": "MDAIASGRLKRKFEDVDVGSPASNSDDEISNSDSADSCDSVNPSSSSGFIPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAPRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESEEAEGLTLEDISDDDIDVENVEVDDYFFLQPLPTKQRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELENKRQGARPGDEELQGSGAAWPPGAQPPETQDFQEFMAENETAVMHLQTAEELERLKAEEDSSGGSGVESVGVCILEEPLAVPEALCPGLAAPILIQAQLPPGSSVLCFADGAEQPAATQPYLNAAPLLYYQVEPRSVLGPKGESGAEECPKDTGTVPAAPTGPCSRAAPAPSKGEGAKGVGQEGAQSCAASLGPSAPREAPGSEQPPQGV", "length": 489, "header": "tr|A0A8V0ZUZ1-1|A0A1D5PNW1_CHICK Computationally mapped isoform of Cysteine and serine rich nuclear protein 2 OS=Gallus gallus OX=9031 GN=CSRNP2 PE=3 SV=1 CANONICAL=A0A1D5PNW1-1" }, "locus": { "chromosome": "34", "start_pos": 2331598, "end_pos": 2326551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058292.1", "url": "https://www.ensembl.org/id/ENSGALT00010058292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035413.1", "url": "https://www.ensembl.org/id/ENSGALP00010035413.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 470, "start_aa": "Thr", "end_pos": 470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1W4-1", "protein_name": "Cysteine and serine rich nuclear protein 2", "gene_name": "Csrnp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKPLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAAEDEPLPGAQSSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGTASFPKEKDLSVFSLPVTSLVACSPSDSAALCKPEVGKAPSLNKLLPDDCNRKEPEREDFHPSWSPSSLPFRTDNEEGCGVQNSQQSEDRTPEDSALELPLAV", "length": 535 }, "evidence": [ { "id": "A0A1D5PNW1", "url": "https://omabrowser.org/oma/group/A0A1D5PNW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BM76-1", "protein_name": "Cysteine and serine rich nuclear protein 2", "gene_name": "CSRNP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTAASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPPAPDEEPSPTTSCSLAAAQGAETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSGIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFAENSDHPTASAVNNPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGPPSFPKEKDLNVFSLPVTSLVACGPTDPAALCKSEVGKTSTLEALVPEDCNPEEPGSEDCRPSWSPSSLPMCTDREEGCAVEKTAPQSADRPPEEPALELPLAV", "length": 543 }, "evidence": [ { "id": "A0A1D5PNW1", "url": "https://omabrowser.org/oma/group/A0A1D5PNW1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BGQ2-1", "protein_name": "Cysteine/serine-rich nuclear protein 2", "gene_name": "Csrnp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFSGSGLKRKFDDVDVGSSVSNSDDEMSSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAEEEPLPGAQSSQTQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSMESLGVCILEEPLAVPQELCPGLAAPILIQAQLPPGSSVLCFTENSEHPAASPMSSPSYLNSGPLVYYQVEQRPVVGVKAESGSEEGPASFPKEKDLSVFSLPVTSLVACGPSASAALCKPEVGKTSSLNKLLPEDCGLKEPESEDLHPSWSPSSLPFRTDNEEGCGVQNSQQSEDRTSEDSALELPLAV", "length": 534 }, "evidence": [ { "id": "A0A1D5PNW1", "url": "https://omabrowser.org/oma/group/A0A1D5PNW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H175-1", "protein_name": "Cysteine/serine-rich nuclear protein 2", "gene_name": "CSRNP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFTGSGLKRKFDDVDVGSSVSNSDDEISSSDSADSCDSLNPPTTASFTPTSILKRQKQLRRKNVRFDQVTVYYFARRQGFTSVPSQGGSSLGMAQRHNSVRSYTLCEFAQEQEVNHREILREHLKEEKLHAKKMKLTKNGTVESVEADGLTLDDVSDEDIDVENVEVDDYFFLQPLPTKRRRALLRASGVHRIDAEEKQELRAIRLSREECGCDCRLYCDPEACACSQAGIKCQVDRMSFPCGCSRDGCGNMAGRIEFNPIRVRTHYLHTIMKLELESKRQVSRPAAPDEEPSPTASCSLTGAQGSETQDFQEFIAENETAVMHLQSAEELERLKAEEDSSGSSASLDSSIESLGVCILEEPLAVPEELCPGLTAPILIQAQLPPGSSVLCFTENSDHPTASTVNSPSYLNSGPLVYYQVEQRPVLGVKGEPGTEEGSASFPKEKDLNVFSLPVTSLVACSSTDPAALCKSEVGKTPTLEALLPEDCNPEEPENEDFHPSWSPSSLPFRTDNEEGCGMVKTSQQNEDRPPEDSSLELPLAV", "length": 543 }, "evidence": [ { "id": "A0A1D5PNW1", "url": "https://omabrowser.org/oma/group/A0A1D5PNW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNW1" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNW1", "url": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0" } ] }, { "name": "TMEM52B", "type": "synonym", "evidence": [ { "id": "XP_424100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424100" } ] } ], "protein_names": [ { "name": "Transmembrane protein 52B", "type": "synonym", "evidence": [ { "id": "A0A1D5PNY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 52B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_424100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424100" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_424100.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424100" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNY0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM52B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0", "locus": { "chromosome": "1", "start_pos": 78475969, "end_pos": 78486661, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024114", "url": "https://www.ensembl.org/id/ENSGALG00010024114" } ] } } ], "crossref": [ { "id": "A0A1D5PNY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PNY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034698", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426455", "url": "https://www.ncbi.nlm.nih.gov/gene/426455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426455", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PNY0", "url": "https://www.orthodb.org/?gene=A0A1D5PNY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZQQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZQ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZZQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZR4", "url": "https://www.orthodb.org/?gene=A0A8V0ZZR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33955:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33955:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNY0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMHNSVIICFVLGCFLWFPKVRSEEGCLNAEFCSGTEWIRLWYIWLVVVIGGLLLLCGLVSVCVRCCLTHCRQAGEESGLQPYEVTVIAFDHDNTLQSTITSLHSVFGPAARRILAVSHSHNTAQGTPPLAASDTPPVYEEALHTSRFTVARAGQKVLDLDPVTKEKLQTSAEDKDAQPVFAEH", "length": 185, "header": "tr|A0A1D5PNY0-1|A0A1D5PNY0_CHICK Isoform 1 of Transmembrane protein 52B OS=Gallus gallus OX=9031 GN=TMEM52B PE=4 SV=1 CANONICAL=A0A1D5PNY0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNY0/entry", "sequence": { "sequence": "MGMHNSVIICFVLGCFLWFPKVRSEEGCLNAEFCSGTEWIRLWYIWLVVVIGGLLLLCGLVSVCVRCCLTHCRQAGEESGLQPYEVTVIAFDHDNTLQSTITSLHSVFGPAARRILAVSHSHNTAQGTPPLAASDTPPVYEEALHTSRFTVARAGQKVLDLDPVTKEKLQTSAEDKDAQPVFAEH", "length": 185, "header": "tr|A0A1D5PNY0-1|A0A1D5PNY0_CHICK Isoform 1 of Transmembrane protein 52B OS=Gallus gallus OX=9031 GN=TMEM52B PE=4 SV=1 CANONICAL=A0A1D5PNY0-1" }, "locus": { "chromosome": "1", "start_pos": 78481138, "end_pos": 78477472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058809.1", "url": "https://www.ensembl.org/id/ENSGALT00010058809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035774.1", "url": "https://www.ensembl.org/id/ENSGALP00010035774.1" } ] } }, { "isoform_ac": "A0A8V0ZQQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ6/entry", "sequence": { "sequence": "ERFEHSKSRHGEENPCCNSRGGNTEIKFPKVRSEEGCLNAEFCSGTEWIRLWYIWLVVVIGGLLLLCGLVSVCVRCCLTHCRQAGEESGLQPYEVTVIAFDHDNTLQSTITSLHSVFGPAARRILAVSHSHNTAQGTPPLAASDTPPVYEEALHTSRFTVARAGQKVLDLDPVTKEKLQTSAEDKDAQPVFAEH", "length": 194, "header": "tr|A0A8V0ZQQ6-1|A0A8V0ZQQ6_CHICK Computationally mapped isoform of Transmembrane protein 52B OS=Gallus gallus OX=9031 GN=TMEM52B PE=4 SV=1 CANONICAL=A0A1D5PNY0-1" }, "locus": { "chromosome": "1", "start_pos": 78480979, "end_pos": 78477472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058804.1", "url": "https://www.ensembl.org/id/ENSGALT00010058804.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035769.1", "url": "https://www.ensembl.org/id/ENSGALP00010035769.1" } ] } }, { "isoform_ac": "A0A8V0ZZQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZQ9/entry", "sequence": { "sequence": "MGMHNSVIICFVLGCFLWFPKVRSEEGCLNAELLVVVIGGLLLLCGLVSVCVRCCLTHCRQAGEESGLQPYEVTVIAFDHDNTLQSTITSLHSVFGPAARRILAVSHSHNTAQGTPPLAASDTPPVYEEALHTSRFTVARAGQKVLDLDPVTKEKLQTSAEDKDAQPVFAEH", "length": 172, "header": "tr|A0A8V0ZZQ9-1|A0A1D5PNY0_CHICK Computationally mapped isoform of Transmembrane protein 52B OS=Gallus gallus OX=9031 GN=TMEM52B PE=4 SV=1 CANONICAL=A0A1D5PNY0-1" }, "locus": { "chromosome": "1", "start_pos": 78481138, "end_pos": 78477472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058807.1", "url": "https://www.ensembl.org/id/ENSGALT00010058807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035772.1", "url": "https://www.ensembl.org/id/ENSGALP00010035772.1" } ] } }, { "isoform_ac": "A0A8V0ZZR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR4/entry", "sequence": { "sequence": "MMFPKVRSEEGCLNAEFCSGTEWIRLWYIWLVVVIGGLLLLCGLVSVCVRCCLTHCRQAGEESGLQPYEVTVIAFDHDNTLQSTITSLHSVFGPAARRILAVSHSHNTAQGTPPLAASDTPPVYEEALHTSRFTVARAGQKVLDLDPVTKEKLQTSAEDKDAQPVFAEH", "length": 169, "header": "tr|A0A8V0ZZR4-1|A0A1D5PNY0_CHICK Computationally mapped isoform of Transmembrane protein 52B OS=Gallus gallus OX=9031 GN=TMEM52B PE=4 SV=1 CANONICAL=A0A1D5PNY0-1" }, "locus": { "chromosome": "1", "start_pos": 78486462, "end_pos": 78477472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058813.1", "url": "https://www.ensembl.org/id/ENSGALT00010058813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035777.1", "url": "https://www.ensembl.org/id/ENSGALP00010035777.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426455", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "uniprot_ac": "A0A1D5PNZ8", "uniprot_id": "A0A1D5PNZ8_CHICK", "mass": { "chemical_mass": 27199.0, "monoisotopic_mass": 27199.0 }, "refseq": { "ac": "XP_040543440", "name": "outer dense fiber protein 3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543440" }, "gene_names": [ { "name": "LOC124417034", "type": "recommended", "evidence": [ { "id": "A0A1D5PNZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8" } ] }, { "name": "LOC124417034", "type": "synonym", "evidence": [ { "id": "XP_040543440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543440" } ] } ], "protein_names": [ { "name": "ODF3A protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PNZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8/entry#names_and_taxonomy" } ] }, { "name": "outer dense fiber protein 3-like", "type": "synonym", "evidence": [ { "id": "XP_040543440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040543440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543440" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNZ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC124417034", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000033320", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "124417034", "url": "https://www.ncbi.nlm.nih.gov/gene/124417034", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101751399", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RAPKYSM", "url": "https://omabrowser.org/oma/group/RAPKYSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNZ8", "url": "https://www.orthodb.org/?gene=A0A1D5PNZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040543440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PNZ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255, "header": "tr|A0A1D5PNZ8-1|A0A1D5PNZ8_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC124417034 PE=4 SV=2 CANONICAL=A0A1D5PNZ8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8/entry", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255, "header": "tr|A0A1D5PNZ8-1|A0A1D5PNZ8_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC124417034 PE=4 SV=2 CANONICAL=A0A1D5PNZ8-1" }, "locus": { "chromosome": "19", "start_pos": 25806, "end_pos": 23033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071205.1", "url": "https://www.ensembl.org/id/ENSGALT00010071205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043896.1", "url": "https://www.ensembl.org/id/ENSGALP00010043896.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101751399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751399", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7FRY9-1", "protein_name": "Outer dense fiber protein 3", "gene_name": "Odf3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEEIWVGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFVKHTPTKLRAPAYSFRGAPMLLAENCSPGPRYSVNPKILRTGKDLGPAYSILGRYQAKTLLTPGPGDYFPEKSTKHVFDSAPSHSISARTKTFRVDSTPGPAAYMLPVVMGPHTVGKVSQPSFSIKGRSKLGSFSDDLHKTPGPAAYRQTDVQVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVILNKPCAPIVTFGIKHSDYMTPLVVDVE", "length": 254 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A1D5PNZ8", "url": "https://omabrowser.org/oma/group/A0A1D5PNZ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PNZ8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PP02-1", "uniprot_ac": "A0A1D5PP02", "uniprot_id": "A0A1D5PP02_CHICK", "mass": { "chemical_mass": 35683.0, "monoisotopic_mass": 35683.0 }, "refseq": { "ac": "XP_419774", "name": "calcium homeostasis modulator protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419774" }, "gene_names": [ { "name": "FAM26D", "type": "recommended", "evidence": [ { "id": "A0A1D5PP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02" } ] }, { "name": "FAM26D", "type": "synonym", "evidence": [ { "id": "XP_419774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419774" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator family member 4", "type": "synonym", "evidence": [ { "id": "A0A1D5PP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02/entry#names_and_taxonomy" } ] }, { "name": "calcium 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by EST evidence. 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"isoforms": [ { "isoform_ac": "A0A1D5PP02-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02/entry", "sequence": { "sequence": "MTFLPKWLTFLKGKEVVIANAIIAILTIGGQQLFSFFTFSCPCRVGQNLIYGLAFLGVPALILLVIGYALNNQTWRLVTGKRSPLLAESTWNQLLQCKLTCFVLCSITGRALVAPVTWLAVTLINGSYYVCAVSEYVSGYYYGDIPNVTISERQRILAAFPCSQLVPPELSRARDEVILLLRYQSQVAGWLVIAVVVITVFLSYCLASCFSPLSFLHFRYWTSYVRNEQELFDEATDQHSKLYAMKHVKKFFGFVPGNENINEIRIPSLREWQAISGLAFLKLVDEEHYDYSLLHDWALKDSADRKYLKLDEDP", "length": 314, "header": "tr|A0A1D5PP02-1|A0A1D5PP02_CHICK Isoform 1 of Calcium homeostasis modulator family member 4 OS=Gallus gallus OX=9031 GN=FAM26D PE=3 SV=1 CANONICAL=A0A1D5PP02-1" }, "locus": { "chromosome": "3", "start_pos": 63516970, "end_pos": 63515202, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035729.1", "url": "https://www.ensembl.org/id/ENSGALT00010035729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020722.1", "url": "https://www.ensembl.org/id/ENSGALP00010020722.1" } ] } } ], 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"MSPDLNCIPSSLLRSEPCINSLIAILTVCGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWAVASEYCCCSCTPPYRRSSPLERRLACLMFFNITGRALVAPLTWLTVTLLTGTYYECAASEFASVDQYPMFANFTPSKREEMLAGFPCYTSAPSDVIPIRDEVALLHRYQSQMLGWILVVLATIAHLVSKCLARCCSPLTSLQHHYWANHLHNERMLFKQAAEEHSRLLIRHRIKKVFGFIPGSEDVKHIRIPSCQDWREISVPNLLCVGDTSQGPYSFLGDRVVEENEEDRQEGIELKP", "length": 315 }, "evidence": [ { "id": "A0A1D5PP02", "url": "https://omabrowser.org/oma/group/A0A1D5PP02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JW98-1", "protein_name": "Calcium homeostasis modulator protein 4", "gene_name": "CALHM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCPTLNNIVSSLQRNGIFINSLIAALTIGGQQLFSSSTFSCPCQVGKNFYYGSAFLVIPALILLVAGFALRSQMWTITGEYCCSCAPPYRRISPLECKLACLRFFSITGRAVIAPLTWLAVTLLTGTYYECAASEFASVDHYPMFDNVSASKREEILAGFPCCRSAPSDVILVRDEIALLHRYQSQMLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDRSRGIELKP", "length": 314 }, "evidence": [ { "id": "A0A1D5PP02", "url": "https://omabrowser.org/oma/group/A0A1D5PP02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CE93-1", "protein_name": "Calcium homeostasis modulator protein 4", "gene_name": "Calhm4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPDLNCISSSLLRSEPCINSLIAILTVCGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWTVASEYCCCSCTPPYRRSSPLERRLACLMFFDITGRALVAPLTWLTVTLLTGTYYECAASEFASVDQYPMFANVTPSKREEMLAGFPCYTSAPSDVIPIRDEVALLHRYQSQMLGWILVVLATIALLLSKCLARCCSPLTSLQHHYWTNHLHNERVLFEKAAEEHSQLLIRHRIKKVFGFVPGSEDIKHIRIPSCQDWREISVPNLLCVGDTSQGPYSFLGDRVVEENEEDRQEGIEMKP", "length": 315 }, "evidence": [ { "id": "A0A1D5PP02", "url": "https://omabrowser.org/oma/group/A0A1D5PP02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP02", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP02", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PP02", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PP02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, 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"XP_419221", "name": "carbonic anhydrase-related protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419221" }, "gene_names": [ { "name": "CA8", "type": "recommended", "evidence": [ { "id": "A0A1D5PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5" } ] }, { "name": "CA8", "type": "synonym", "evidence": [ { "id": "XP_419221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419221" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase-related protein", "type": "recommended", "evidence": [ { "id": "A0A1D5PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5/entry#names_and_taxonomy" } ] }, { "name": "Carbonic anhydrase VIII", "type": "synonym", "evidence": [ { "id": "A0A1D5PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5/entry#names_and_taxonomy" } ] }, { "name": "carbonic anhydrase-related protein", "type": "synonym", "evidence": [ { "id": "XP_419221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419221" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_419221.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419221" } ] }, { "annotation": "Does not have a carbonic anhydrase catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5#function" }, { "database": "UniProtKB", "id": "ARBA00060169", "url": "https://www.uniprot.org/uniprotkb/ARBA00060169#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CA8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5", "locus": { "chromosome": "2", "start_pos": 112403462, "end_pos": 112455650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002685", "url": "https://www.ensembl.org/id/ENSGALG00010002685" } ] } } ], "crossref": [ { "id": "A0A1D5PPM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039145", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03120", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03120", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421139", "url": "https://www.ncbi.nlm.nih.gov/gene/421139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CTEGIVW", "url": "https://omabrowser.org/oma/group/CTEGIVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPM5", "url": "https://www.orthodb.org/?gene=A0A1D5PPM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XE24", "url": "https://www.orthodb.org/?gene=A0A8V0XE24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGS5", "url": "https://www.orthodb.org/?gene=A0A8V0XGS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XE24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRSLIEGAEPFPRREEAPEWGYEEGVEWGLIFPDANGEYQSPINLNSREAKYDPSLLEVRLSPNYVVCRDCEVINDGHSIQIALKSKSVLIGGPLPRGHEFELHDVRFHWGRENQRGSEHTVNFKAFPMELHLMHWNSTLYSSIDEAVGKKHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNSLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTVSQVQIEEFRRLRTHVKGAELLEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 283, "header": "tr|A0A1D5PPM5-1|A0A1D5PPM5_CHICK Isoform 1 of Carbonic anhydrase-related protein OS=Gallus gallus OX=9031 GN=CA8 PE=1 SV=1 CANONICAL=A0A1D5PPM5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5/entry", "sequence": { "sequence": "MADRSLIEGAEPFPRREEAPEWGYEEGVEWGLIFPDANGEYQSPINLNSREAKYDPSLLEVRLSPNYVVCRDCEVINDGHSIQIALKSKSVLIGGPLPRGHEFELHDVRFHWGRENQRGSEHTVNFKAFPMELHLMHWNSTLYSSIDEAVGKKHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNSLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTVSQVQIEEFRRLRTHVKGAELLEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 283, "header": "tr|A0A1D5PPM5-1|A0A1D5PPM5_CHICK Isoform 1 of Carbonic anhydrase-related protein OS=Gallus gallus OX=9031 GN=CA8 PE=1 SV=1 CANONICAL=A0A1D5PPM5-1" }, "locus": { "chromosome": "2", "start_pos": 112455567, "end_pos": 112419017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006225.1", "url": "https://www.ensembl.org/id/ENSGALT00010006225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003867.1", "url": "https://www.ensembl.org/id/ENSGALP00010003867.1" } ] } }, { "isoform_ac": "A0A8V0XE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE24/entry", "sequence": { "sequence": "MLHLMHWNSTLYSSIDEAVGKKHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNSLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTVSQVQIEEFRRLRTHVKGAELLEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 152, "header": "tr|A0A8V0XE24-1|A0A1D5PPM5_CHICK Computationally mapped isoform of Carbonic anhydrase-related protein OS=Gallus gallus OX=9031 GN=CA8 PE=1 SV=1 CANONICAL=A0A1D5PPM5-1" }, "locus": { "chromosome": "2", "start_pos": 112443466, "end_pos": 112419017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006222.1", "url": "https://www.ensembl.org/id/ENSGALT00010006222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003865.1", "url": "https://www.ensembl.org/id/ENSGALP00010003865.1" } ] } }, { "isoform_ac": "A0A8V0XGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGS5/entry", "sequence": { "sequence": "MGPPFEFVEVSLDGISSSLHVGCISQLHLMHWNSTLYSSIDEAVGKKHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNSLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTVSQVQIEEFRRLRTHVKGAELLEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 177, "header": "tr|A0A8V0XGS5-1|A0A1D5PPM5_CHICK Computationally mapped isoform of Carbonic anhydrase-related protein OS=Gallus gallus OX=9031 GN=CA8 PE=1 SV=1 CANONICAL=A0A1D5PPM5-1" }, "locus": { "chromosome": "2", "start_pos": 112447656, "end_pos": 112419017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006224.1", "url": "https://www.ensembl.org/id/ENSGALT00010006224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003866.1", "url": "https://www.ensembl.org/id/ENSGALP00010003866.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SLG9-1", "protein_name": "Carbonic anhydrase-related protein", "gene_name": "CA8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADLSFIEDSVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 291 }, "evidence": [ { "id": "A0A1D5PPM5", "url": "https://omabrowser.org/oma/group/A0A1D5PPM5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P28651-1", "protein_name": "Carbonic anhydrase-related protein", "gene_name": "Ca8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADLSFIEDAVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 291 }, "evidence": [ { "id": "A0A1D5PPM5", "url": "https://omabrowser.org/oma/group/A0A1D5PPM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35219-1", "protein_name": "Carbonic anhydrase-related protein", "gene_name": "CA8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 290 }, "evidence": [ { "id": "A0A1D5PPM5", "url": "https://omabrowser.org/oma/group/A0A1D5PPM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PPN4-1", "protein_name": "Carbonic anhydrase-related protein", "gene_name": "Ca8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLSFIEDAVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIVIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ", "length": 290 }, "evidence": [ { "id": "A0A1D5PPM5", "url": "https://omabrowser.org/oma/group/A0A1D5PPM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PPM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 283, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PPM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPM5" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 282, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PPP9-1", "uniprot_ac": "A0A1D5PPP9", "uniprot_id": "A0A1D5PPP9_CHICK", "mass": { "chemical_mass": 12028.0, "monoisotopic_mass": 12028.0 }, "refseq": { "ac": "XP_015146987", "name": "prothymosin alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146987" }, "gene_names": [ { "name": "PTMA", "type": "recommended", "evidence": [ { "id": "A0A1D5PPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP9" } ] }, { "name": "PTMA", "type": "synonym", "evidence": [ { "id": "XP_015146987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146987" } ] } ], "protein_names": [ { "name": "Prothymosin alpha", "type": "synonym", "evidence": [ { "id": "A0A1D5PPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP9/entry#names_and_taxonomy" } ] }, { "name": "prothymosin alpha", "type": "synonym", "evidence": [ { "id": "XP_015146987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146987" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146987" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTMA", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPP9", "locus": {} } ], "crossref": [ { "id": "A0A1D5PPP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043329", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043329", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424931", "url": "https://www.ncbi.nlm.nih.gov/gene/424931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424931", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEESCPR", "url": "https://omabrowser.org/oma/group/VEESCPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22745", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22745", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22745:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22745:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03247", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03247", "database": "Pfam", "categories": [ 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PPY1-1", "uniprot_ac": "A0A1D5PPY1", "uniprot_id": "A0A1D5PPY1_CHICK", "mass": { "chemical_mass": 96253.0, "monoisotopic_mass": 96253.0 }, "refseq": { "ac": "XP_046785646", "name": "cAMP-regulated phosphoprotein 21 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046785646" }, "gene_names": [ { "name": "ARPP21", "type": "recommended", "evidence": [ { "id": "A0A1D5PPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1" } ] }, { "name": "ARPP21", "type": "synonym", "evidence": [ { "id": "XP_046785646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046785646" } ] } ], "protein_names": [ { "name": "cAMP regulated phosphoprotein 21", "type": "synonym", "evidence": [ { "id": "A0A1D5PPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1/entry#names_and_taxonomy" } ] }, { "name": "cAMP-regulated phosphoprotein 21 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046785646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046785646" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046785646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046785646" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARPP21", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1", "locus": { "chromosome": "2", "start_pos": 45463999, "end_pos": 45332954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018378", "url": "https://www.ensembl.org/id/ENSGALG00010018378" } ] } } ], "crossref": [ { "id": "A0A1D5PPY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043240", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043240", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02642", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02642", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428459", "url": "https://www.ncbi.nlm.nih.gov/gene/428459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428459", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5L3", "url": "https://www.orthodb.org/?gene=A0A8V0Z5L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15672:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15672:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046785646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046785646", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PPY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z652", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z652", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z652-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z652-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z736", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z736", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z736-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z736-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z764", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z764", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z764-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z764-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQVLLPTKSCFAKPKKKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIPEQRFSEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRILPFRDDRRSKSIEEREEEYQRVRERIFAQDSVCSQENLFVENSRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 870, "header": "tr|A0A1D5PPY1-1|A0A1D5PPY1_CHICK Isoform 1 of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQVLLPTKSCFAKPKKKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIPEQRFSEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRILPFRDDRRSKSIEEREEEYQRVRERIFAQDSVCSQENLFVENSRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 870, "header": "tr|A0A1D5PPY1-1|A0A1D5PPY1_CHICK Isoform 1 of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45463434, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044394.1", "url": "https://www.ensembl.org/id/ENSGALT00010044394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026422.1", "url": "https://www.ensembl.org/id/ENSGALP00010026422.1" } ] } }, { "isoform_ac": "A0A8V0Z5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J8/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQVLLPTKSCFAKPKKKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIQFAPRKTFLWKTVGSWKTVVYAMIPIRKDSCLAATGDDKTTGGGEELELAEKLHGLG", "length": 313, "header": "tr|A0A8V0Z5J8-1|A0A8V0Z5J8_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45400889, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044370.1", "url": "https://www.ensembl.org/id/ENSGALT00010044370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026403.1", "url": "https://www.ensembl.org/id/ENSGALP00010026403.1" } ] } }, { "isoform_ac": "A0A8V0Z5L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5L3/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIPEQRFSEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRILPFRDDRRSKSIEEREEEYQRVRERIFAQDSVCSQENLFVENSRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 857, "header": "tr|A0A8V0Z5L3-1|A0A8V0Z5L3_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45463434, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044390.1", "url": "https://www.ensembl.org/id/ENSGALT00010044390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026418.1", "url": "https://www.ensembl.org/id/ENSGALP00010026418.1" } ] } }, { "isoform_ac": "A0A8V0Z652-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z652/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 774, "header": "tr|A0A8V0Z652-1|A0A8V0Z652_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45463434, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044378.1", "url": "https://www.ensembl.org/id/ENSGALT00010044378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026410.1", "url": "https://www.ensembl.org/id/ENSGALP00010026410.1" } ] } }, { "isoform_ac": "A0A8V0Z736-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z736/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRISHRNHKVLRGYKVLLMVEMQCKIPGGLNVCWHVFCSPL", "length": 280, "header": "tr|A0A8V0Z736-1|A0A8V0Z736_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45375899, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044366.1", "url": "https://www.ensembl.org/id/ENSGALT00010044366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026399.1", "url": "https://www.ensembl.org/id/ENSGALP00010026399.1" } ] } }, { "isoform_ac": "A0A8V0Z764-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z764/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQVLLPTKSCFAKPKKKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIPEQRFSEHLKDEKGEESQKRFILKRDNSSIDKEDNQSVCSQENLFVENSRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 837, "header": "tr|A0A8V0Z764-1|A0A8V0Z764_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45463434, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044396.1", "url": "https://www.ensembl.org/id/ENSGALT00010044396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026424.1", "url": "https://www.ensembl.org/id/ENSGALP00010026424.1" } ] } }, { "isoform_ac": "A0A8V0ZD38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD38/entry", "sequence": { "sequence": "MSEQGKLSQETAEEAAKEQESAISEATPDNCILNKSESSELEEKEEKLSDGKTELQVLLPTKSCFAKPKKKRGANQQKKRSKSGAKGKLVRSLAVCEESSPRPGAETLHDNQESIQLQLSSFPSLQEEDKTNKDDSEKEKEKDKNKEKDKSSDKNKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNPRDRMILLKMEQEIIDFISDNNNHYKKFPQMSSYQRMLVHRVAAYFGMDHNVDQTGKSVIINKTSNTRIRLLEDSSICNDTHKKRQLFRGNRDSTGKASGSRQSSTENELKWTDHQRPWSSTDSDSSNRNLKPAITKTASFGGITVLTRGDSSSSNRSTGKLSKTGSSESSSSAGSSGSLSRIHQPLQSAPLVPGLTASNSGSVSYPENGMSGQVAPSNTSYIILPLEAAGIPPGSILLNPHTGQPFVNPDGTPAIYNPPSSQPTMRSQMVGQSQQQPSSQQPQQVQQPQQQMASHLVTQPVQAMQPSSQSVQYPAVSYPPQHLLPVSPTQQFSVRDDMTTQFNQMSLSRQSSGDNPESPSGPVYPSPILQQPAQQTGYIMASPTQQLPPGGFTGSGPPVSQQVLQPPPPPQGFVQQPPPPAQMPVYYYPSGQYPTSTTQQYRPIASVQYNAQRSQQIPQTAQQAGYQPVLPNQQQGFQGLMGMQQPPQSQSLMNNQQGNQVQGMMVQYPAMSSYQVPMTQGSQGLPQQSYQQPIMLPNQSGQGTLTATGMPVYCNVIPPAPQNNLRLIAPHCPSNNVPVISASCRTNCASINNAGWQVKY", "length": 788, "header": "tr|A0A8V0ZD38-1|A0A8V0ZD38_CHICK Computationally mapped isoform of cAMP regulated phosphoprotein 21 OS=Gallus gallus OX=9031 GN=ARPP21 PE=4 SV=1 CANONICAL=A0A1D5PPY1-1" }, "locus": { "chromosome": "2", "start_pos": 45463434, "end_pos": 45365196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044403.1", "url": "https://www.ensembl.org/id/ENSGALT00010044403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026427.1", "url": "https://www.ensembl.org/id/ENSGALP00010026427.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 522, "start_aa": "Thr", "end_pos": 522, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr522", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428459", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PPY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PPY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 870, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PPY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PPY1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 522, 599 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 808, "end_pos": 810 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQ65-1", "uniprot_ac": "A0A1D5PQ65", "uniprot_id": "A0A1D5PQ65_CHICK", "mass": { "chemical_mass": 48857.0, "monoisotopic_mass": 48857.0 }, "refseq": { "ac": "XP_418167", "name": "keratin, type I cytoskeletal 23", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418167" }, "gene_names": [ { "name": "KRT23", "type": "recommended", "evidence": [ { "id": "A0A1D5PQ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ] }, { "name": "KRT23", "type": "synonym", "evidence": [ { "id": "XP_418167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418167" } ] } ], "protein_names": [ { "name": "Keratin 23", "type": "synonym", "evidence": [ { "id": "A0A1D5PQ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65/entry#names_and_taxonomy" } ] }, { "name": "keratin, type I cytoskeletal 23", "type": "synonym", "evidence": [ { "id": "XP_418167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418167" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_418167.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418167" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KRT23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65", "locus": { "chromosome": "27", "start_pos": 4528504, "end_pos": 4538153, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022817", "url": "https://www.ensembl.org/id/ENSGALG00010022817" } ] } } ], "crossref": [ { "id": "A0A1D5PQ65", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQ65", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039447", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420044", "url": "https://www.ncbi.nlm.nih.gov/gene/420044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420044", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCILEWH", "url": "https://omabrowser.org/oma/group/SCILEWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQ65", "url": "https://www.orthodb.org/?gene=A0A1D5PQ65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZJT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418167", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTSQGPFQFYSGSLRGSAGCGLAQQGTSYRPPSADGASGTHTSFSSTRPLSLAAGGGASWGCFGEHHWESIFLGGNEKQTMQNLNDRLAAYLDKVRSLEAANAQLESCILEWHKTKSHGKRHDFNQYEQNVTDMQRQIEDGKITNASILLQIDNANMASEDFRLKYEAEKTRRQGVQCDLENLRKELDGLTIITTDLEMEIEGLREEHILRRKDHEEDMEANRSSQDFKVNVKVNAPPPEDLTKILAEIREDYEAIIEKNRQSLDSWYKELSTAVSLAADPNPEQVQSSENEIKDLTRTLQSLDIELQAQMSKKHMLEDTLADTRNYYAVALQNMQQTISKCEEELSQLRHDIRQQHNQYRVLLGIKTRLEKEISTYRLLLEGNVDRITRTCESKAEEYAELTNGKIKAIVHDSMNGQLLSSTTAIHQEE", "length": 431, "header": "tr|A0A1D5PQ65-1|A0A1D5PQ65_CHICK Isoform 1 of Keratin 23 OS=Gallus gallus OX=9031 GN=KRT23 PE=3 SV=2 CANONICAL=A0A1D5PQ65-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65/entry", "sequence": { "sequence": "MSTSQGPFQFYSGSLRGSAGCGLAQQGTSYRPPSADGASGTHTSFSSTRPLSLAAGGGASWGCFGEHHWESIFLGGNEKQTMQNLNDRLAAYLDKVRSLEAANAQLESCILEWHKTKSHGKRHDFNQYEQNVTDMQRQIEDGKITNASILLQIDNANMASEDFRLKYEAEKTRRQGVQCDLENLRKELDGLTIITTDLEMEIEGLREEHILRRKDHEEDMEANRSSQDFKVNVKVNAPPPEDLTKILAEIREDYEAIIEKNRQSLDSWYKELSTAVSLAADPNPEQVQSSENEIKDLTRTLQSLDIELQAQMSKKHMLEDTLADTRNYYAVALQNMQQTISKCEEELSQLRHDIRQQHNQYRVLLGIKTRLEKEISTYRLLLEGNVDRITRTCESKAEEYAELTNGKIKAIVHDSMNGQLLSSTTAIHQEE", "length": 431, "header": "tr|A0A1D5PQ65-1|A0A1D5PQ65_CHICK Isoform 1 of Keratin 23 OS=Gallus gallus OX=9031 GN=KRT23 PE=3 SV=2 CANONICAL=A0A1D5PQ65-1" }, "locus": { "chromosome": "27", "start_pos": 4538103, "end_pos": 4528910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055501.1", "url": "https://www.ensembl.org/id/ENSGALT00010055501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033619.1", "url": "https://www.ensembl.org/id/ENSGALP00010033619.1" } ] } }, { "isoform_ac": "A0A8V0ZJT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT4/entry", "sequence": { "sequence": "MSTSQGPFQFYSGSLRGSAGCGLAQQGTSYRPPSADGASGTHTSFSSTRPLSLAAGGGASWGCFGEHHWESIFLGGNEKQTMQNLNDRLAAYLDKVRSLEAANAQLESCILEWHKTKSHGKRHDFNQYEQNVTDMQRQIEDGKITNASILLQIDNANMASEDFRLKYEAEKTRRQGVQCDLENLRKELDGLTIITTDLEMEIEGLREEHILRRKDHEEDMEANRSSQDFKVNVKVNAPPPEDLTKILAEIREDYEAIIEKNRQSLDSWYKELSTAVSLAADPNPEQVQSSENEIKDLTRTLQSLDIELQAQMSKKHMLEDTLADTRNYYAVALQNMQQTISKCEEELSQLRHDIRQQHNQYRVLLGIKTRLEKEISTYRLLLEGNVDRITRTCESKAEGKSPLSCSL", "length": 407, "header": "tr|A0A8V0ZJT4-1|A0A8V0ZJT4_CHICK Computationally mapped isoform of Keratin 23 OS=Gallus gallus OX=9031 GN=KRT23 PE=3 SV=1 CANONICAL=A0A1D5PQ65-1" }, "locus": { "chromosome": "27", "start_pos": 4538103, "end_pos": 4529622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055496.1", "url": "https://www.ensembl.org/id/ENSGALT00010055496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033614.1", "url": "https://www.ensembl.org/id/ENSGALP00010033614.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420044", "resource": "KEGG Pathway" }, { "id": "R-GGA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-GGA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZLV8-1", "protein_name": "Keratin 23", "gene_name": "Krt23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSSHSFNQTYSASVHSLGSTWGQRGSCHRTPSVHGGAGGVRISLSFTTPGCLPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANSKLESRILQWHQEREPSTKKDYSQYEENISHLQEQIVDGKMANAHIVVLIDNARMAVDDFNLKFENEHSLKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEMEENHWPSDFKVNVKVDTTPGEDLIKVLEDMRQEYELIIKKKHQELDTWFREQSASMAQGVASPVPVQGSQSDIHELRRTFQALEIDLQAQHNRKSALENMLTETQARYSCRLQDMQQIISHYEEELIQLRQDLERQNNEHKVLLGIKTHLEKEIATYRRLLEGDTEGTRDEPESRLKGSPASMIKAITQESVNGRIVLSQVNEIQKHL", "length": 422 }, "evidence": [ { "id": "A0A1D5PQ65", "url": "https://omabrowser.org/oma/group/A0A1D5PQ65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MI65-1", "protein_name": "Keratin 23", "gene_name": "KRT23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSNQSFSQKRSGSLYATGGSWGRPGSFLRAPSVHGGAGGVRISLSFSSPSCPLPEGSWRSGRGSSLLGGNEKEMMQNLNDRLATYLEKVRALEEANVKLESCILKWHQQRDSGNKQDYSQYEESISHLQEQIADGKVNNAQIILLIDNARMAVDDFSLKYENEHSFKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEVEEHRVPNDFKVNVKVDTTPGEDLIKVLEDMRQEYEFIIKKKHQDLDTWYKQQSAAVAQEAASPTGVQSSQSDLHELKRTFQALEIDLQAQCSKKSALENMLSETQSRYSCQLQDMQQIISHYEEELTQLRHDLERQNNEYKVLLGIKTHLEKEITTYRQLLEGENGGKMEESKSNVKAPKIKAITQESVNGRIILSQVNEI", "length": 415 }, "evidence": [ { "id": "A0A1D5PQ65", "url": "https://omabrowser.org/oma/group/A0A1D5PQ65/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99PS0-1", "protein_name": "Keratin, type I cytoskeletal 23", "gene_name": "Krt23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSHSFNQTYSASVHSLGSTRGRQGSCHRAPSVHGGAGGVRISLSFTTPGCLPPGGSWGSGRSSPLLGGNGKATMQNLNDRLATYLEKVRALEEANSKLETRILRWHQEREPSHRKDYSQYEENISRLQEQIVDGKMANAHIVVLIDNARMAVDDFNLKFENEHSLKKDLEIEVEGLRKTLDDLTIVTTDLEQEVEGMRKELILMKKRHEQEMEENHLPSDFKVSVKVDTTPGEDLIKVLEDMRQEYELIIKKKHQELDTWFREQSAAMAQEVASPAPVQGNQSDIHELRRTFQALEIDLQAQHSRKTALENMLTETRARYSCRLQDMQQIISHYEEELIQLRQDLERQNNEHKVLLGIKTHLEKEIATYRRLLEGDTEGTMDGSESRLKGSEASTIKAITQESVNGRIVLSQVNEIQKHI", "length": 422 }, "evidence": [ { "id": "A0A1D5PQ65", "url": "https://omabrowser.org/oma/group/A0A1D5PQ65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C075-1", "protein_name": "Keratin, type I cytoskeletal 23", "gene_name": "KRT23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSMKVSATPKIKAITQETINGRLVLCQVNEIQKHA", "length": 422 }, "evidence": [ { "id": "A0A1D5PQ65", "url": "https://omabrowser.org/oma/group/A0A1D5PQ65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PQ65-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 431, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PQ65-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQ65" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQA4-1", "uniprot_ac": "A0A1D5PQA4", "uniprot_id": "A0A1D5PQA4_CHICK", "mass": { "chemical_mass": 28483.0, "monoisotopic_mass": 28483.0 }, "refseq": { "ac": "NP_001313428", "name": "uncharacterized protein LOC421419 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313428" }, "gene_names": [ { "name": "LOC421419", "type": "recommended", "evidence": [ { "id": "A0A1D5PQA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4" } ] }, { "name": "LOC421419", "type": "synonym", "evidence": [ { "id": "NP_001313428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313428" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A1D5PQA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC421419 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001313428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313428" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.24474.1, SRR13267655.16610.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On May 19, 2016 this sequence version replaced XP_419472.3. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. It encodes a shorter isoform (2) compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313428", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313428" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQA4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC421419", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4", "locus": {} } ], "crossref": [ { "id": "A0A1D5PQA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042797", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042797", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421419", "url": "https://www.ncbi.nlm.nih.gov/gene/421419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A1D5PQA4", "url": "https://www.orthodb.org/?gene=A0A1D5PQA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD18", "url": "https://www.orthodb.org/?gene=A0A8V0ZD18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR41142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41142:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41142:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001313428", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQA4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKVLTKKLRNQTLNEIQPFQLKISYPPSDEDSDDSEGENQELVQIDRERRRNCTLTPLATNQLQNQENQCCKVRALLHASLDRHSSEEELERINREFAAEKRKWSQVSRLACCSDSNNTSSSDEEVKNLCAMSFQPVAEQADGLHASPSPVLFSASPPKRLQPLVRNPASRPLILTGVGAGLEQVMPCKRHRQGYGDKICRPSLDLEKMQQSINGGRPPPHFVYDPSTFAFRSLSTLKPLSPIAPVEEPSCAY", "length": 254, "header": "tr|A0A1D5PQA4-1|A0A1D5PQA4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC421419 PE=4 SV=2 CANONICAL=A0A1D5PQA4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4/entry", "sequence": { "sequence": "MLKVLTKKLRNQTLNEIQPFQLKISYPPSDEDSDDSEGENQELVQIDRERRRNCTLTPLATNQLQNQENQCCKVRALLHASLDRHSSEEELERINREFAAEKRKWSQVSRLACCSDSNNTSSSDEEVKNLCAMSFQPVAEQADGLHASPSPVLFSASPPKRLQPLVRNPASRPLILTGVGAGLEQVMPCKRHRQGYGDKICRPSLDLEKMQQSINGGRPPPHFVYDPSTFAFRSLSTLKPLSPIAPVEEPSCAY", "length": 254, "header": "tr|A0A1D5PQA4-1|A0A1D5PQA4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC421419 PE=4 SV=2 CANONICAL=A0A1D5PQA4-1" }, "locus": { "chromosome": "3", "start_pos": 27445095, "end_pos": 27394005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048504.1", "url": "https://www.ensembl.org/id/ENSGALT00010048504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028601.1", "url": "https://www.ensembl.org/id/ENSGALP00010028601.1" } ] } }, { "isoform_ac": "A0A8V0ZD18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD18/entry", "sequence": { "sequence": "MKRQFFTGWLIFIRHCRKQLPLPSERRRNCTLTPLATNQLQNQENQCCKVRALLHASLDRHSSEEELERINREFAAEKRKWSQVSRLACCSDSNNTSSSDEEVKNLCAMSFQPVAEQADGLHASPSPVLFSASPPKRLQPLVRNPASRPLILTGVGAGLEQVMPCKRHRQGYGDKICRPSLDLEKMQQKMLLKKNSGMKTRVIKIRSINGGRPPPHFVYDPSTFAFRSLSTLKPLSPIAPVEEPSCAY", "length": 248, "header": "tr|A0A8V0ZD18-1|A0A8V0ZD18_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC421419 PE=4 SV=1 CANONICAL=A0A1D5PQA4-1" }, "locus": { "chromosome": "3", "start_pos": 27445095, "end_pos": 27384418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048509.1", "url": "https://www.ensembl.org/id/ENSGALT00010048509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028605.1", "url": "https://www.ensembl.org/id/ENSGALP00010028605.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQA4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQA4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PQA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PQA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQA4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 119, "end_pos": 121 }, { "start_pos": 11, "end_pos": 13 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A1D5PQB5-1", "uniprot_ac": "A0A1D5PQB5", "uniprot_id": "A0A1D5PQB5_CHICK", "mass": { "chemical_mass": 52082.0, "monoisotopic_mass": 52082.0 }, "refseq": { "ac": "NP_001138698", "name": "immunoglobulin superfamily member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" }, "gene_names": [ { "name": "IGSF1", "type": "recommended", "evidence": [ { "id": "A0A1D5PQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5" } ] }, { "name": "FCR", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] }, { "name": "IGSF1L3", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] }, { "name": "IGSF1", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] } ], "protein_names": [ { "name": "Fc Receptor", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] }, { "name": "Immunoglobulin superfamily member 1", "type": "synonym", "evidence": [ { "id": "A0A1D5PQB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5/entry#names_and_taxonomy" } ] }, { "name": "immunoglobulin superfamily member 1-like 3", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] }, { "name": "immunoglobulin superfamily member 1", "type": "synonym", "evidence": [ { "id": "NP_001138698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: FM200428.1, ERR2368565.327021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On Oct 29, 2010 this sequence version replaced NP_001138698.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ] }, { "annotation": "Gallus gallus FcR, an additional immunoglobulin (Ig)Y FcR present in chicken, is highly related to genes encoded in the leukocyte receptor complex and not to genes in the FcR region; Gallus gallus FcR selectively binds chicken IgY.", "evidence": [ { "database": "RefSeq", "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" }, { "database": "PubMed", "id": "19155501", "url": "https://glygen.org/publication/PubMed/19155501" } ] }, { "annotation": "Indicates that a substantial shift in the nature of Fc receptor binding occurred during the evolution of mammalian IgG and IgE.", "evidence": [ { "database": "RefSeq", "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" }, { "database": "PubMed", "id": "19733585", "url": "https://glygen.org/publication/PubMed/19733585" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQB5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGSF1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5", "locus": { "chromosome": "20", "start_pos": 384848, "end_pos": 381148, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021327", "url": "https://www.ensembl.org/id/ENSGALG00010021327" } ] } } ], "crossref": [ { "id": "A0A1D5PQB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030005", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030005", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419114", "url": "https://www.ncbi.nlm.nih.gov/gene/419114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419114", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWMWTHR", "url": "https://omabrowser.org/oma/group/GWMWTHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQB5", "url": "https://www.orthodb.org/?gene=A0A1D5PQB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC25", "url": "https://www.orthodb.org/?gene=A0A8V0ZC25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQB5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQSICKRTGSVSPASVFIRRNPALIEKYKRGMMLPATHMLAFSVWLVAQSKATASAPTVSIFLQPPGVIPLGGSTTICCRCLCHGGKMVLYKDGYQLRTLELHGNTAEFSISKATQMDRGLYSCHYVDGGNGTVLTRSDSMEVRVEEFCLPKPVLSVQPGHEVAAGADVMLHCTIRLSKVVCFLYLEGQATALKISVEHTDFYLSRMDHSKGGRYSCQCYTEGTPINWSGVSNMLELVVRESLLPGPSISVTPQEGAILGTSATVHCMCQCHQTVMLLYKSGNVSIQQRAWPVRGMATFIITQVAQEDGGAYACRYGNESDPSSLSQLSPFAELLVRDHKLVRPSLSLKPLGRVQLGTNVTLWCTSGVQRAQFYFWKNWEIVGVIEQESNVATFVLPHVMGHNGGTYTCSYRPWSQRYISSQPSNSVLLTVVDYTRSNIVRLALGVGVLILLGLMVAEAMNSQRNTPGQLPPLE", "length": 475, "header": "tr|A0A1D5PQB5-1|A0A1D5PQB5_CHICK Isoform 1 of Immunoglobulin superfamily member 1 OS=Gallus gallus OX=9031 GN=IGSF1 PE=4 SV=1 CANONICAL=A0A1D5PQB5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5/entry", "sequence": { "sequence": "MKQSICKRTGSVSPASVFIRRNPALIEKYKRGMMLPATHMLAFSVWLVAQSKATASAPTVSIFLQPPGVIPLGGSTTICCRCLCHGGKMVLYKDGYQLRTLELHGNTAEFSISKATQMDRGLYSCHYVDGGNGTVLTRSDSMEVRVEEFCLPKPVLSVQPGHEVAAGADVMLHCTIRLSKVVCFLYLEGQATALKISVEHTDFYLSRMDHSKGGRYSCQCYTEGTPINWSGVSNMLELVVRESLLPGPSISVTPQEGAILGTSATVHCMCQCHQTVMLLYKSGNVSIQQRAWPVRGMATFIITQVAQEDGGAYACRYGNESDPSSLSQLSPFAELLVRDHKLVRPSLSLKPLGRVQLGTNVTLWCTSGVQRAQFYFWKNWEIVGVIEQESNVATFVLPHVMGHNGGTYTCSYRPWSQRYISSQPSNSVLLTVVDYTRSNIVRLALGVGVLILLGLMVAEAMNSQRNTPGQLPPLE", "length": 475, "header": "tr|A0A1D5PQB5-1|A0A1D5PQB5_CHICK Isoform 1 of Immunoglobulin superfamily member 1 OS=Gallus gallus OX=9031 GN=IGSF1 PE=4 SV=1 CANONICAL=A0A1D5PQB5-1" }, "locus": { "chromosome": "20", "start_pos": 384153, "end_pos": 381321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051697.1", "url": "https://www.ensembl.org/id/ENSGALT00010051697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030835.1", "url": "https://www.ensembl.org/id/ENSGALP00010030835.1" } ] } }, { "isoform_ac": "A0A8V0ZC25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC25/entry", "sequence": { "sequence": "MMLPATHMLAFSDISVSTGAPTVSIFLQPPGVIPLGGSTTICCRCLCHGGKMVLYKDGYQLRTLELHGNTAEFSISKATQMDRGLYSCHYVDGGNGTVLTRSDSMEVRVEEFCLPKPVLSVQPGHEVAAGADVMLHCTIRLSKVVCFLYLEGQATALKISVEHTDFYLSRMDHSKGGRYSCQCYTEGTPINWSGVSNMLELVVRESLLPGPSISVTPQEGAILGTSATVHCMCQCHQTVMLLYKSGNVSIQQRAWPVRGMATFIITQVAQEDGGAYACRYGNESDPSSLSQLSPFAELLVRDHKLVRPSLSLKPLGRVQLGTNVTLWCTSGVQRAQFYFWKNWEIVGVIEQESNVATFVLPHVMGHNGGTYTCSYRPWSQRYISSQPSNSVLLTVVDYTRSNIVRLALGVGVLILLGLMVAEAMNSQRNTPGQLPPLE", "length": 438, "header": "tr|A0A8V0ZC25-1|A0A8V0ZC25_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 1 OS=Gallus gallus OX=9031 GN=IGSF1 PE=4 SV=1 CANONICAL=A0A1D5PQB5-1" }, "locus": { "chromosome": "20", "start_pos": 384153, "end_pos": 381417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051693.1", "url": "https://www.ensembl.org/id/ENSGALT00010051693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030832.1", "url": "https://www.ensembl.org/id/ENSGALP00010030832.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A novel activating chicken IgY FcR is related to leukocyte receptor complex (LRC) genes but is located on a chromosomal region distinct from the LRC and FcR gene clusters.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2009-02-01", "authors": "Viertlboeck Birgit C, Schmitt Ramona, Hanczaruk Matthias A, Crooijmans Richard P M A, Groenen Martien A M, G\u00f6bel Thomas W", "evidence": [ { "database": "RefSeq", "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ], "reference": [ { "type": "PubMed", "id": "19155501", "url": "https://glygen.org/publication/PubMed/19155501" } ] }, { "title": "Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites.", "journal": "Developmental and comparative immunology", "date": "2010-02", "authors": "Taylor Alexander I, Sutton Brian J, Calvert Rosaleen A", "evidence": [ { "database": "RefSeq", "id": "NP_001138698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138698" } ], "reference": [ { "type": "PubMed", "id": "19733585", "url": "https://glygen.org/publication/PubMed/19733585" } ] } ], "pathway": [ { "id": "gga:419114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419114", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8N149-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily A member 2", "gene_name": "LILRA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHPQDYTVENLIRMGVAGLVLVVLGILLFEAQHSQRSLQDAAGR", "length": 483 }, "evidence": [ { "id": "A0A1D5PQB5", "url": "https://omabrowser.org/oma/group/A0A1D5PQB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQB5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQB5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQB5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, 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"Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 360, "end_pos": 362 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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(ubiquinone) complex I, assembly factor 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138423" }, "gene_names": [ { "name": "NDUFAF6", "type": "recommended", "evidence": [ { "id": "A0A1D5PQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5" } ] }, { "name": "NDUFAF6", "type": "synonym", "evidence": [ { "id": "XP_015138423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138423" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "type": "recommended", "evidence": [ { "id": "A0A1D5PQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138423" } ] }, { "annotation": "Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of complex I subunit MT-ND1.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5#function" }, { "database": "UniProtKB", "id": "ARBA00056665", "url": "https://www.uniprot.org/uniprotkb/ARBA00056665#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFAF6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5", "locus": { "chromosome": "2", "start_pos": 126029311, "end_pos": 126012053, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012583", "url": "https://www.ensembl.org/id/ENSGALG00010012583" } ] } } ], "crossref": [ { "id": "A0A1D5PQC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040366", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040366", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420233", "url": "https://www.ncbi.nlm.nih.gov/gene/420233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MINAREQ", "url": "https://omabrowser.org/oma/group/MINAREQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQC5", "url": "https://www.orthodb.org/?gene=A0A1D5PQC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAATAAGGLRPVSFPRLLRAVGARGGLPWPRGGRAAAAGWSRPEPGGEAQYCAELLRKRDYEGFLCSLLLPAESRTSAFALRAFNVELAQIKDSITQKTTGLMRMQFWRKAVEDIYCDNPPHQPVAVALWRAVKRHNLSKMWFMKIIDEREKNLDDRAYRNIQELETYAENTQSALFYLTLEMLGVRDVHADHAASHIGKAQGIVTCLRATPYHCARRKVFLPMDICMLHGVSQEDFIRCKQEKHVRDVIYDIASQAHIHLEHARSFSKKVPVKAYPAFYYTVALDDYLYNIRKVDFNIFHPSLQKRNTLLPLYLYIRTWKKTY", "length": 325, "header": "tr|A0A1D5PQC5-1|A0A1D5PQC5_CHICK Isoform 1 of NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Gallus gallus OX=9031 GN=NDUFAF6 PE=3 SV=1 CANONICAL=A0A1D5PQC5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5/entry", "sequence": { "sequence": "MAAATAAGGLRPVSFPRLLRAVGARGGLPWPRGGRAAAAGWSRPEPGGEAQYCAELLRKRDYEGFLCSLLLPAESRTSAFALRAFNVELAQIKDSITQKTTGLMRMQFWRKAVEDIYCDNPPHQPVAVALWRAVKRHNLSKMWFMKIIDEREKNLDDRAYRNIQELETYAENTQSALFYLTLEMLGVRDVHADHAASHIGKAQGIVTCLRATPYHCARRKVFLPMDICMLHGVSQEDFIRCKQEKHVRDVIYDIASQAHIHLEHARSFSKKVPVKAYPAFYYTVALDDYLYNIRKVDFNIFHPSLQKRNTLLPLYLYIRTWKKTY", "length": 325, "header": "tr|A0A1D5PQC5-1|A0A1D5PQC5_CHICK Isoform 1 of NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Gallus gallus OX=9031 GN=NDUFAF6 PE=3 SV=1 CANONICAL=A0A1D5PQC5-1" }, "locus": { "chromosome": "2", "start_pos": 126029296, "end_pos": 126012075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030148.1", "url": "https://www.ensembl.org/id/ENSGALT00010030148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017510.1", "url": "https://www.ensembl.org/id/ENSGALP00010017510.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420233", "resource": "KEGG Pathway" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AIL4-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "Ndufaf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSMLGSVRGPRPFGLANLFHRQPPRDAWERVRRLPGPSAVRRSVAAASGPGIPGSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQVKDSVSEKTIGLMRMQFWKKAVEDMYCDNPPHQPVAIELWKAVKKHNLTKRWLMRIIDEREKNLDDKAYRSMQELENYAENTQGSLLYLTLEVLGVKDLHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLRRNQDKNVRDVVYDIASQAHLHLKHARSFHRSVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNMLLPLSLYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7YVD7-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "NDUFAF6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASTLGSAWGPLRLGVPGLCRRRPPRGLWARARRLSEPVASGRSVAAGSGLGASGTDRYCLELLRKRDYEGYLCSLLLPAESRSSAFALRAFNVELAQIKDSVSEKTIGLMRMQFWKKTVDDIYSDNPPHQPVAIELWKAVRRHNLTKRWLMKIIDEREKNLDDKAYRNIQELENYAENTQSSLLYLTLEILGIKDLHADHAASHIGKAQGIVTCLRATPYHGSRRRVFLPMDICMLHGVSQEDFLRKSQDRNVRDVVYDVASQAHLHLKHARSFHRSIPVKAFPAFLQTVALEDYLKKIQQVDFDLFHPSLQRKNTLLPLSLYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZN43-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "Ndufaf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSMLGSVPGPRPFGLAGLFRRRPPRDPWERVRRLPRLSAVRRSVAAASGPGIPDSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQVKDSVSEKTIGLMRMQFWRKAVEDMFCDNPPHQPVAMELWKAVKRHNLTKRWLLRIIDEREKNLDDKAYRSIRELETYAENTQSSLLYLTLEVLGVKDVHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLRRNQDKNVRDVVYDIASQAHLHLKHARSFHSRVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNTLLPLSLYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RY58-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "NDUFAF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASMLGSAWGPLRLGLPGLCRRRPPGGLWARARRLPGSAGSGRSVAAASGSGASGTDRYCMELLRKRDYEGYLCSLLFPAESRSSAFALRAFNVELAQVKDSVSEKTIGLMRMQFWKKTVDDIYCDSPPHQPVAIELWKAVKRHNLTKRWLMKIIDEREKNLDDKAYRNIQELENYAENTQSSLLYLTLEILGVKDLHADHAASHIGKAQGIVTCLRATPYHGSRRRVFLPMDICMLHGVSQEDFLRKSQDKNVRDVVYDIASQAHLHLKHARSFHKSVPAKAFPAFLQTVALEDYLKKIQQVDFDIFHPSLQQKNTLLPLSVYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q330K2-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "NDUFAF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASAHGSVWGPLRLGIPGLCCRRPPLGLYARMRRLPGPEVSGRSVAAASGPGAWGTDHYCLELLRKRDYEGYLCSLLLPAESRSSVFALRAFNVELAQVKDSVSEKTIGLMRMQFWKKTVEDIYCDNPPHQPVAIELWKAVKRHNLTKRWLMKIVDEREKNLDDKAYRNIKELENYAENTQSSLLYLTLEILGIKDLHADHAASHIGKAQGIVTCLRATPYHGSRRKVFLPMDICMLHGVSQEDFLRRNQDKNVRDVIYDIASQAHLHLKHARSFHKTVPVKAFPAFLQTVSLEDFLKKIQRVDFDIFHPSLQQKNTLLPLYLYIQSWRKTY", "length": 333 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54E48-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRNSGRILFNSLKNSNVKLINRNVIINSNIRLFSTSTNNTIKESVEKKAETISNKDNIASPSSKSIDVSDLAGNADYNFVFERIKTCDKENYINSLLISDPIARRVAYAIRAFNIETVANDHSPKSEKISRLRLSFWKDAINNIYNGKVYDQPLTRVLAQVIKEKKLTKTWFIKILNRREKDNQQVQIKDMEELEQYADDIHSSLMLLTLEGLGVKGNHDVEHCASHLGKAIGIMVLIRGTVYHLASRKTYIPVSLTTKYGINVESLYRGDPQIEKLQNAIYEMASCAKLHLDKAKQFRGKIPHPATEAFLSVSVVEDFLERLRKADFNIFEFPNTQQHPLLLIKLYKNKFFKQF", "length": 356 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SI77-1", "protein_name": "Terpenoid synthases superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNGGGSSSLRSALSYCVQQVRNYDYHHYLCLLELPTEMRKAAFALRAFNVETARAMDVASDPKIGLMRLLWWQEAIDKLYTKKPINHPAAQALSWAISEHNISKPWLKRSVDARIRDAQREVDDIPESIAELEKYAEDTVSTLLYNTLQAGGISSTTADHAASHIGKASGLVLLLKSLPYHCTRNRHQSYIPADLAEKHGLLVKQGGRLEILLDNDSREGLSNVVFEIASVANAHLLKARELAGKVPAEAKPVLLHSVPVQVLLDSLNKVQFDVFDPRIQRGVLGVPPLLFQFKLKWYSWRAMF", "length": 304 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VYS5-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog", "gene_name": "sicily", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRLVRNWNCRLLFNAKSGQEIVSHAGIHQEAKTNAIPREKKVIEADKNGYGAKHCMSLVEKYDYENYLCTLLLPRELRRAAFALRAFNVEVSRSVSGHQIEPQIAKMRLKFWHDSIDKCFEPDSQRSYVEDQPVLRELKHTVGSRKLNKVYLRRLVTARERPPTHAFESIRELEEYTEQTFSSLLLLLLEVGGVRDLNADHAASHLGKAQGIATLLRSIPLAGRQQAPCIPLEVLVLHGVSQERIIRSKSDDKGVEDCIFDVASAANTHLKLARQLHDKVPPQVRKIFLSAVATDAYLERLRRANFLLTHKSCVGRDTLLPARLFWKSLLNRF", "length": 334 }, "evidence": [ { "id": "A0A1D5PQC5", "url": "https://omabrowser.org/oma/group/A0A1D5PQC5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQC5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PQC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 325, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PQC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQC5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQD0-1", "uniprot_ac": "A0A1D5PQD0", "uniprot_id": "A0A1D5PQD0_CHICK", "mass": { "chemical_mass": 135617.0, "monoisotopic_mass": 135617.0 }, "refseq": { "ac": "XP_015148657", "name": "intraflagellar transport protein 122 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148657" }, "gene_names": [ { "name": "IFT122", "type": "recommended", "evidence": [ { "id": "A0A1D5PQD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0" } ] }, { "name": "IFT122", "type": "synonym", "evidence": [ { "id": "XP_015148657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148657" } ] } ], "protein_names": [ { "name": "Intraflagellar transport protein 122 homolog", "type": "recommended", "evidence": [ { "id": "A0A1D5PQD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0/entry#names_and_taxonomy" } ] }, { "name": "intraflagellar transport protein 122 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015148657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148657" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148657" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFT122", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0", "locus": { "chromosome": "12", "start_pos": 19693874, "end_pos": 19663071, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019144", "url": "https://www.ensembl.org/id/ENSGALG00010019144" } ] } } ], "crossref": [ { "id": "A0A1D5PQD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008452", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008452", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416123", "url": "https://www.ncbi.nlm.nih.gov/gene/416123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQD0", "url": "https://www.orthodb.org/?gene=A0A1D5PQD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG97", "url": "https://www.orthodb.org/?gene=A0A8V0ZG97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12764", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12764", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12764:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12764:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQD0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAALTWRDRAEHCIYDLAFKPDGTQLIIAAGNRLLVYDTSDGTLIQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTHNDSIQCVSYNPLTHQLASCSSSDFGLWSPEQKSVSKHKAGSKITCCSWTNDGQYLALGMFNGVISIRNKNGDEKVKIERTGAGSSPIWSICWNPSRDERNDTLAVADWGQRLSFYQLSGKQIGKDRMLNFDPCCVSYFTKGEYILLGGSDKQVSLFTKDGVRLGTIGEQSSWVWTCRAKPDSNYVAVGCQDGTIAFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKGRELVKKIAIYKNRLAIQMPEKILIYELYSDDSSDMYYRVKEKIVKKFECNLLVVCSDHIILCQEKRLQCLSFSGVKEREWLMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNVFAIVLLKQSTAVRCLDMSASRNKLAVVDENDTCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAGNFPVHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLERKMFKEAYQIACLGVTDADWRELAMEALEGLEFETAKKAFTRIRDLRYLELISSIEERKKHGENLNELFLADVYAYQGKFHEAAKLYKKSGRESLALDMYSDLRMFDYAKDFLRSGDPKDTKMLIKKQADWAKNINEPKAAVEMYLSAGEHMKAIEISGDHGWVDMLIEIARKLDKAEREPLSKCAFYFKKLDNPGYAAETYMKVGDLKALVSLHVETHHWEEAFALSEKHPEFKDEVYVPYAQWLAENDRFEEAQKAFHKAGRQREAVRVLEQLTHNAVVESRFNDAAYYYWMLSMQCLDIAQENEEQKTEMLQKFHHFQQLAEVYHVYHYIQRYTEEPFSFHLPETLFNISRFLLHSLTKETPLGISKVNTLFALAKQSKALGAYKLARHAYDKLQGLQIPARFQKSVELGSLTIRSKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFVFSASSYEVLHLVEFYLEEGITDEEAVSLIDLEAPRLNKSGNKWQEMMGDDAQSLRLNDSAVITEDDDPFTAKLSFEQGSSEFVPVIVNRAVLQSMSRRDVLIKRWPKPLRWQYYRSLLPDASITMCPSCFQMFHTEDYELLVLQHNCCPFCRRRIDESNQ", "length": 1184, "header": "tr|A0A1D5PQD0-1|A0A1D5PQD0_CHICK Isoform 1 of Intraflagellar transport protein 122 homolog OS=Gallus gallus OX=9031 GN=IFT122 PE=1 SV=2 CANONICAL=A0A1D5PQD0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQD0/entry", "sequence": { "sequence": 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"length": 1184, "header": "tr|A0A1D5PQD0-1|A0A1D5PQD0_CHICK Isoform 1 of Intraflagellar transport protein 122 homolog OS=Gallus gallus OX=9031 GN=IFT122 PE=1 SV=2 CANONICAL=A0A1D5PQD0-1" }, "locus": { "chromosome": "12", "start_pos": 19693516, "end_pos": 19663160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046336.1", "url": "https://www.ensembl.org/id/ENSGALT00010046336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027598.1", "url": "https://www.ensembl.org/id/ENSGALP00010027598.1" } ] } }, { "isoform_ac": "A0A8V0ZG97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG97/entry", "sequence": { "sequence": 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"length": 1172, "header": "tr|A0A8V0ZG97-1|A0A8V0ZG97_CHICK Computationally mapped isoform of Intraflagellar transport protein 122 homolog OS=Gallus gallus OX=9031 GN=IFT122 PE=1 SV=1 CANONICAL=A0A1D5PQD0-1" }, "locus": { "chromosome": "12", "start_pos": 19693516, "end_pos": 19663160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046324.1", "url": "https://www.ensembl.org/id/ENSGALT00010046324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027589.1", "url": "https://www.ensembl.org/id/ENSGALP00010027589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": 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"https://www.uniprot.org/uniprotkb/A0A1D5PQM9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 104 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150881" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150881" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM104", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9", "locus": { "chromosome": "18", "start_pos": 11128346, "end_pos": 11086688, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029667", "url": "https://www.ensembl.org/id/ENSGALG00010029667" } ] } } ], "crossref": [ { "id": "A0A1D5PQM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007747", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422110", "url": "https://www.ncbi.nlm.nih.gov/gene/422110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422110", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422110", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHREGHP", "url": "https://omabrowser.org/oma/group/GHREGHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQM9", "url": "https://www.orthodb.org/?gene=A0A1D5PQM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16189:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16189:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRX5", "url": "https://www.uniprot.org/uniprotkb/F1NRX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRX5-1", "url": "https://www.uniprot.org/uniprotkb/F1NRX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGITDTGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLMFLGFMSYMTTTFVVEAMAAANAQLRWKRMEKRKEDDEDEDSSSGVSDSDVLLRDSYERAETRPILSVQRRGSPNIFEITERVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPVSLMQVTCSAIGNHSCNVGDGTKYNDTDKCWGPIRRIDAYRLYLAAFTLLLGPFTFFNVQKTKYLQIMTSLMRWIAFILMIILALIRISRGQAEGHPSMAQLSGIRNLFGVCVYSFMCQHSLPSLITPISKKRHVNKLVLLDYILILAFYSLLSFTAIYCFRNDTLMDMYTLNFTNCEIINVAFIRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWLVDRIVFPAITLVPPVLVAFCTHDLESLVGITGAYAGNGIQYLIPAFLAYCSRKDTQLVFGSGTVNKHLSPFRHTFWIVFVLIWGFSCFVFVTANIVLSESKL", "length": 498, "header": "tr|A0A1D5PQM9-1|A0A1D5PQM9_CHICK Isoform 1 of Putative sodium-coupled neutral amino acid transporter 12 OS=Gallus gallus OX=9031 GN=TMEM104 PE=3 SV=1 CANONICAL=A0A1D5PQM9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9/entry", "sequence": { "sequence": "MAGGITDTGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLMFLGFMSYMTTTFVVEAMAAANAQLRWKRMEKRKEDDEDEDSSSGVSDSDVLLRDSYERAETRPILSVQRRGSPNIFEITERVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPVSLMQVTCSAIGNHSCNVGDGTKYNDTDKCWGPIRRIDAYRLYLAAFTLLLGPFTFFNVQKTKYLQIMTSLMRWIAFILMIILALIRISRGQAEGHPSMAQLSGIRNLFGVCVYSFMCQHSLPSLITPISKKRHVNKLVLLDYILILAFYSLLSFTAIYCFRNDTLMDMYTLNFTNCEIINVAFIRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWLVDRIVFPAITLVPPVLVAFCTHDLESLVGITGAYAGNGIQYLIPAFLAYCSRKDTQLVFGSGTVNKHLSPFRHTFWIVFVLIWGFSCFVFVTANIVLSESKL", "length": 498, "header": "tr|A0A1D5PQM9-1|A0A1D5PQM9_CHICK Isoform 1 of Putative sodium-coupled neutral amino acid transporter 12 OS=Gallus gallus OX=9031 GN=TMEM104 PE=3 SV=1 CANONICAL=A0A1D5PQM9-1" }, "locus": { "chromosome": "18", "start_pos": 11125102, "end_pos": 11087407, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071745.1", "url": "https://www.ensembl.org/id/ENSGALT00010071745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044435.1", "url": "https://www.ensembl.org/id/ENSGALP00010044435.1" } ] } }, { "isoform_ac": "F1NRX5-1", "url": "https://www.uniprot.org/uniprotkb/F1NRX5/entry", "sequence": { "sequence": "MAGGITDTGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLMFLGFMSYMTTTFVVEAMAAANAQLRWKRMEKRKEDDEDEDSSSGVSDSDVLLRDSYERAETRPILSVQRRGSPNIFEITERVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPVSLMQVTCAIGNHSCNVGDGTKYNDTDKCWGPIRRIDAYRLYLAAFTLLLGPFTFFNVQKTKYLQIMTSLMRWIAFILMIILALIRISRGQAEGHPSMAQLSGIRNLFGVCVYSFMCQHSLPSLITPISKKRHVNKLVLLDYILILAFYSLLSFTAIYCFRNDTLMDMYTLNFTNCEIINVAFIRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWLVDRIVFPAITLVPPVLVAFCTHDLESLVGITGAYAGNGIQYLIPAFLAYCSRKDTQLVFGSGTVNKHLSPFRHTFWIVFVLIWGFSCFVFVTANIVLSESKL", "length": 497, "header": "tr|F1NRX5-1|A0A1D5PQM9_CHICK Computationally mapped isoform of Putative sodium-coupled neutral amino acid transporter 12 OS=Gallus gallus OX=9031 GN=TMEM104 PE=3 SV=1 CANONICAL=A0A1D5PQM9-1" }, "locus": { "chromosome": "18", "start_pos": 11125102, "end_pos": 11087407, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071744.1", "url": "https://www.ensembl.org/id/ENSGALT00010071744.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044434.1", "url": "https://www.ensembl.org/id/ENSGALP00010044434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422110", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422110", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATA1-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "TMEM104", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGEITETGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFLGFMSFVTTTFVVEAMAAANAQLRWKRMENHQQEEDDDSSSASDSDVLIQNNYERAEKRPILSVQRRGSPNLFEITDRVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPFSLMQVTCALGNDSCGVEADAKYNDTDLCWGPLRRVDAYRIYLAVFTLLLGPFTFFDVQKTKYLQILTSLMRWIAFAIMIVLALVRIGQGRGEGHPPLADLSGVRNLFGVCVYSFMCQHSLPSLVTPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGDSLLDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWVVDRVVFPTITLLPPVLVAFCTHDLESLVGITGAYAGTGIQYIIPAFLVYLCRKDTQLAFGYGTVNKHRSPFRHTFWVGFVLLWAFSCFFFVTANIVLSETKL", "length": 495 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M5C4-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "Tmem104", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGEITETGELYSPYVGLVYMFNLIVGTGALTMPKAFASAGWLVSLVLLVFLGFMSFVTTTFVMEAMAAANAQLRWKRMETHKEEEDEDSSTASDSDILTQDNYERAEKRPILSVQRRSSANLFEITDRVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPFSLMQVTCSVSGNDSCGVDTDAKYNDTDLCWGPLRRVDAYRIYLAVFTLLLGPFTFFNVQKTKYLQILTSLMRWVAFAIMIVLALVRIGNRQGEGHPPLANFLGVRNLFGVCVYSFMCQHSLPSLITPISSKRHVTRLLFLDYGLILAFYGLLSFTAIFCFRGDSLMDMYTLNFARCDVVSLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWVVDRVVFPTITLVPPILVAFCTHDLESLVGITGAYAGTGIQYVIPAFLVYLCRKDTQLTFGYGTINKHRSPFRHTLWVAFVLLWAFSCFFFVTANIVLSETQL", "length": 496 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F9F2-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "slc38a12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGGITETGEPYSPFVGLVYMFNLIVGTGALTMPKAFAAAGWVVSVSLITFLAFMSFMTTTFVIEAMAAANAQLRWKRREQEEVNDSDSSSDYSDDEVIIRGRSEPVETRPILSVQRAANIDHFDIVERVEMGQMASMFFNKVGVNMFYICIIVYLYGDLAIYAAAVPVSLMEVACGNHSCSAGSVKYNDTESCWGPVRRKDAYRVFLAIFTLLLGPFTFFNAQKTKYLQILTSLMRWIAFTMMIILALIRIGKGHGEGKPSVAQISGVPNLFGVCVYSFMCQHSLPSLVTPISNKQRMSILVMADYILILCFYALLSLTAIFCFDSSLLRDMYTLNFTDNCDVLGVPVLRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHRDGGTYPWVVDRVVFPLITLVPPIIVAFCTHDLESLVGITGAYAGTGIQYIIPAFLVYFSRRHLEPVLGRDAVNKHRSPFRHTFWVCFVVLWATFCLMFVTANIVLNETKN", "length": 493 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3TB48-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "SLC38A12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGEITETGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFVGFMSFVTTTFAMEAMAAANAQLRWKRMETHKEEDDEDSSTASDSDLLSQDNYERAEKRPILSVQRRSSANLFEITDRVEMGQMASMFFNKVGVNLFYFCIITYLYGDLAIYAAAVPVSLMQVTCSVSGNDSCGVDTDARYNDTDLCWGPLRRVDVYRIYLAIFTVLLGPFTFFDVQKTKYLQILTSMMRWIAFAIMIVLALVRIGKGQGEGHPPLANFLGVQNLFGVCVYSFMCQHSLPSLITPISSKRHITRLLFLDYALILAFYGLLSFTAIFCFRGDSLMDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWVVDRVVFPTITLVPPILVAFCTHDLESLVAITGAYAGTGIQYVIPAFLVYLCRKDTQLTFGYGTVNKHRSPFRHTFWVAFVLLWAFSCFFFVTAYIVLKETQL", "length": 496 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54S12-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "tmem104", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAGGPSDGSTYSKKTAFVYIFNLIVGVGALALPYGFSKAGLVLGLLFLAAIGFLAFITATWLIEGLSIANFILVNKKEERIIGDDDNENYQKPPTENDSLINSEYSDNKILQSNAEDRNLLEPSGGSSSSDNEQFEIKKRVEVGEMSKMFLGNIGYKVFYGVLIIYLFGDLSIYAATVPTTLANVTGGWGKFTDHTVYYFYLFLFACFVGPFSLFNFQKTKYLQFATLITRNVAFLLMIILSIIFIAQGNGASIKQVPIFEISELASIFGVSIYSFMTHHSIPGFLTPISKKDRLFTLMGLDFILVFIAYGTLCVVSLFAFGAVTNPTCATASTSIHTFIPCQIQSLYIYNFTSYNSKFVSDFLSLFPVFTLSTNYILISITLRNNLLQLITWKQDKISSKVRNVVFSLTSSLIPVGVAFCTRNVSLLVNITGSYAGLGIMFVMPALISFYSNKILIEQYHISNPKKSPFSNKFFYLLILLISVICLILATWKIIITYK", "length": 499 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NE00-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "SLC38A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGEITETGELYSSYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFLGFMSFVTTTFVIEAMAAANAQLHWKRMENLKEEEDDDSSTASDSDVLIRDNYERAEKRPILSVQRRGSPNPFEITDRVEMGQMASMFFNKVGVNLFYFCIIVYLYGDLAIYAAAVPFSLMQVTCSATGNDSCGVEADTKYNDTDRCWGPLRRVDAYRIYLAIFTLLLGPFTFFDVQKTKYLQILTSLMRWIAFAVMIVLALIRIGHGQGEGHPPLADFSGVRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGDSLMDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWVVDRVVFPTITLVPPVLVAFCTHDLESLVGITGAYAGTGIQYVIPAFLVYHCRRDTQLAFGCGVSNKHRSPFRHTFWVGFVLLWAFSCFIFVTANIILSETKL", "length": 496 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPF8-1", "protein_name": "Putative sodium-coupled neutral amino acid transporter 12", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPRLVNGREAAPTYSNLVGFIFIFNLIVGTGALTLPGVFARAGWMLSLIVIVLLAIISYMTVTFIIEAMACANAIRNWQTLQALRQSRSSAENSENDDNADDVSLASGAEQVGDFERVPLTIQNREFHYYQLSHKFELGEMATLFFNEFGRVMFYLCLIVYLYGDLSIYSAAVARSLRDVVCDQTNGTDTNNLMYWPGDFENNTSLACWKEHTISRLNMYRVLLIGFTLIFGPFVYFNVQKTKYLQMLTAAFRWMAFTLMICISLKLLISRGAKGHPATFNVYGIPSLFGACVYSFMCHHSLPSLLAPIRHKSMVSKILSIDYIIICAFYILLAMTGIFAFERIEDLYTLDFLPYDVAYVDFWSGLLICIDYFLALFPIFTLSTSFPIVAITLKNNLQSLFLDMSQYESYSVILRLCFPLLAIIPPFCITYFTESLSSLVAFTGTYAGTGIQYIIPVFLVYFARRTCSELLGSGVVNRFKSPFKSSAWLVFVFIWSILCVCLVSINLFS", "length": 509 }, "evidence": [ { "id": "A0A1D5PQM9", "url": "https://omabrowser.org/oma/group/A0A1D5PQM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQM9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PQM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 498, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PQM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQM9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQM9" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 67, "start_aa": "Tyr", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PQZ9-1", "uniprot_ac": "A0A1D5PQZ9", "uniprot_id": "A0A1D5PQZ9_CHICK", "mass": { "chemical_mass": 69684.0, "monoisotopic_mass": 69684.0 }, "refseq": {}, "gene_names": [ { "name": "KLHL14", "type": "recommended", "evidence": [ { "id": "A0A1D5PQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ] } ], "protein_names": [ { "name": "Kelch-like protein 14", "type": "recommended", "evidence": [ { "id": "A0A1D5PQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9", "locus": { "chromosome": "2", "start_pos": 106239194, "end_pos": 106299791, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005252", "url": "https://www.ensembl.org/id/ENSGALG00010005252" } ] } } ], "crossref": [ { "id": "A0A1D5PQZ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036969", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036969", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18243", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18243", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421100", "url": "https://www.ncbi.nlm.nih.gov/gene/421100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421100", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RETRMQH", "url": "https://omabrowser.org/oma/group/RETRMQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQZ9", "url": "https://www.orthodb.org/?gene=A0A1D5PQZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012884", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSGGGHPHALALGPGAQDGLGGAPPKEPPPPPQEEPGTPSSSPEDKLLASPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLVLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKNLYVIGGRNETGYLSSVECYNLETNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYSPEKGTWTELEGDVAEPLAGPACSTVILPACVPYNK", "length": 622, "header": "tr|A0A1D5PQZ9-1|A0A1D5PQZ9_CHICK Isoform 1 of Kelch-like protein 14 OS=Gallus gallus OX=9031 GN=KLHL14 PE=4 SV=2 CANONICAL=A0A1D5PQZ9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9/entry", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSGGGHPHALALGPGAQDGLGGAPPKEPPPPPQEEPGTPSSSPEDKLLASPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLVLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKNLYVIGGRNETGYLSSVECYNLETNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYSPEKGTWTELEGDVAEPLAGPACSTVILPACVPYNK", "length": 622, "header": "tr|A0A1D5PQZ9-1|A0A1D5PQZ9_CHICK Isoform 1 of Kelch-like protein 14 OS=Gallus gallus OX=9031 GN=KLHL14 PE=4 SV=2 CANONICAL=A0A1D5PQZ9-1" }, "locus": { "chromosome": "2", "start_pos": 106299128, "end_pos": 106241777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012440.1", "url": "https://www.ensembl.org/id/ENSGALT00010012440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007004.1", "url": "https://www.ensembl.org/id/ENSGALP00010007004.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421100", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PS01-1", "protein_name": "Kelch-like protein 14", "gene_name": "klhl14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGVRSPEVMSRSGDRTSTFDPTHSDTLLHGLNLLWRKQLFCDVTLTAQGQQFHCHRAVLASCSQYFRSLFSTHSMLSREDGLAAKDQGSSGTPSSSPDDKLLPSPHSTINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILNIPQITKLSVQFLNDQISVQNYKQICKIAALHGLDETKKLANKYLVEDVLLLNFEEMCAMLDALPPPVESELALFQMSVLWLEHDRETRMHYAPDLMKRLRFALIPAPELVERVQSVDFMRSDPVCQKLLLDAMNYHLMPFRQHCRQTTASRIRSNKRMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLLLLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFFACCLDKHLYVVGGRNETGYLSSVEAYNLETNEWNYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVSWLYCYDPVMDVWARKQDMNTKRAIHALAGMNDRLYAIGGNHLKGFSHLDVMLVECYDPKADQWSILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYSPEKATWTEMEGEVAEPLAGPACATVILPACLPFNK", "length": 616 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZYQ7-1", "protein_name": "Kelch-like protein 14", "gene_name": "Klhl14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDQQQQQQPQQQPSQQQQQPPQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLDTNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACATVILPACVPYNK", "length": 630 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BPK1-1", "protein_name": "Kelch-like protein 14", "gene_name": "KLHL14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDPPQQPPQQQPPPPPAQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLETNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGSWTELEGDVAEPLAGPACATVILPACVPYNK", "length": 626 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SAK5-1", "protein_name": "Kelch-like protein 14", "gene_name": "KLHL14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDPQQQQQPPQQPPQQQQPPPQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLETNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACATVILPACVPYNK", "length": 630 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q69ZK5-1", "protein_name": "Kelch-like protein 14", "gene_name": "Klhl14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDQQQQQQPQQQPPQQQQPPPQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLDTNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACATVILPACVPYNK", "length": 630 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2G3-1", "protein_name": "Kelch-like protein 14", "gene_name": "KLHL14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDQQQPPQQQPSQQQQPPPQEEPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSVSKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNFEEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVERVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGPDRLPSNLVQYYDDEKKTWKILTIMPYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNSWIQLPPMQERRASFYACRLDKHLYVIGGRNETGYLSSVECYNLETNEWRYVSSLPQPLAAHAGAVHNGKIYISGGVHNGEYVPWLYCYDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWNILQTPILEGRSGPGCAVLDDSIYLVGGYSWSMGAYKSSTICYCPEKGTWTELEGDVAEPLAGPACVTVILPSCVPYNK", "length": 628 }, "evidence": [ { "id": "A0A1D5PQZ9", "url": "https://omabrowser.org/oma/group/A0A1D5PQZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PQZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 622, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PQZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PQZ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PQZ9", "database": "UniProtKB", "url": 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combination :: AJ851580.1, SRR12888497.431935.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On Sep 4, 2012 this sequence version replaced NP_001012573.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001012573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRH9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRH9", "locus": { "chromosome": "2", "start_pos": 135436769, "end_pos": 135425108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009273", "url": "https://www.ensembl.org/id/ENSGALG00010009273" } ] } } ], "crossref": [ { "id": "A0A1D5PRH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRH9", 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"MSAGGAVPPPPNPAVSFPAPRVTLPAGPDILRTYSGAFVCLEIVLGGLVWILVASSNVPLPLLQGWVMFVSVTAFFFSLLFLGLFLSGMVTQIDANWNFLDFVYHFIVFVFYFGAFLLEAAATSLHDLQCNTTMTVKPLLNDNQYNINVAATVFAFMTTACYGCSLGLALRRWRP", "length": 175 }, "evidence": [ { "id": "A0A1D5PRH9", "url": "https://omabrowser.org/oma/group/A0A1D5PRH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969L2-1", "protein_name": "Protein MAL2", "gene_name": "MAL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVPLPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLEAAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP", "length": 176 }, "evidence": [ { "id": "A0A1D5PRH9", "url": "https://omabrowser.org/oma/group/A0A1D5PRH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151696" } ] } ], "protein_names": [ { "name": "Smoothelin like 2", "type": "synonym", "evidence": [ { "id": "A0A1D5PRI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5/entry#names_and_taxonomy" } ] }, { "name": "smoothelin-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151696" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151696" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRI5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMTNL2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5", "locus": { "chromosome": "19", "start_pos": 10394010, "end_pos": 10430828, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029305", "url": "https://www.ensembl.org/id/ENSGALG00010029305" } ] } } ], "crossref": [ { "id": "A0A1D5PRI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006069", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006069", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417687", "url": "https://www.ncbi.nlm.nih.gov/gene/417687", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417687", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417687", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APHQGER", "url": "https://omabrowser.org/oma/group/APHQGER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PRI5", "url": "https://www.orthodb.org/?gene=A0A1D5PRI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHD4", "url": "https://www.orthodb.org/?gene=A0A8V1AHD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PRI5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEIDNLNSHEAKTVCEALGRYEDTLRGAVREIHVDIQVFKQGVSRQVDEVLRLASPLARTVSELQQENQRLRVQLERLARQVEALGRSAGLPQEWQEEAERSPPAVGPSSPVPAFSGDRFSTLAKLAVSGRSQSVDLDDHHKPEFRRVFSSSLIENGHQSSSGQAKASHELTSFYMSDSSPEAHAPAMTLQMPHLPVTAVTRISEKFSGENIHSAGTTNASTGLLGQNQSKNEMTLKTSNQSVRTMTSSANGVNATSVTKPVSTASYEASSGNKTGESAADSYCGMTPKAHSSPPTVHRQVERRRELVRSQTLPRTTGTQARKALFEKFEQDSGKGKGQSRAKLKRSQSFGVASASSIKQILLDWCRSKTIGYKHIDLQNFSSSWNDGMAFCALVHSFFPESFDYNKLDPANRKQNFELAFTMAEKMAHCDRLIEVDDMMMMGHKPDPMCVFTYVQSLYNHLRHFE", "length": 468, "header": "tr|A0A1D5PRI5-1|A0A1D5PRI5_CHICK Isoform 1 of Smoothelin like 2 OS=Gallus gallus OX=9031 GN=SMTNL2 PE=3 SV=1 CANONICAL=A0A1D5PRI5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5/entry", "sequence": { "sequence": "MASEIDNLNSHEAKTVCEALGRYEDTLRGAVREIHVDIQVFKQGVSRQVDEVLRLASPLARTVSELQQENQRLRVQLERLARQVEALGRSAGLPQEWQEEAERSPPAVGPSSPVPAFSGDRFSTLAKLAVSGRSQSVDLDDHHKPEFRRVFSSSLIENGHQSSSGQAKASHELTSFYMSDSSPEAHAPAMTLQMPHLPVTAVTRISEKFSGENIHSAGTTNASTGLLGQNQSKNEMTLKTSNQSVRTMTSSANGVNATSVTKPVSTASYEASSGNKTGESAADSYCGMTPKAHSSPPTVHRQVERRRELVRSQTLPRTTGTQARKALFEKFEQDSGKGKGQSRAKLKRSQSFGVASASSIKQILLDWCRSKTIGYKHIDLQNFSSSWNDGMAFCALVHSFFPESFDYNKLDPANRKQNFELAFTMAEKMAHCDRLIEVDDMMMMGHKPDPMCVFTYVQSLYNHLRHFE", "length": 468, "header": "tr|A0A1D5PRI5-1|A0A1D5PRI5_CHICK Isoform 1 of Smoothelin like 2 OS=Gallus gallus OX=9031 GN=SMTNL2 PE=3 SV=1 CANONICAL=A0A1D5PRI5-1" }, "locus": { "chromosome": "19", "start_pos": 10416471, "end_pos": 10395297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070873.1", "url": "https://www.ensembl.org/id/ENSGALT00010070873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043564.1", "url": "https://www.ensembl.org/id/ENSGALP00010043564.1" } ] } }, { "isoform_ac": "A0A8V1AHD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD4/entry", "sequence": { "sequence": "MASEIDNLNSHEAKTVCEALGRYEDTLRGAVREIHVDIQVFKQGVSRQVDEVLRLASPLARTVSELQQENQRLRVQLERLARQVEALGRSAGLPQEWQEEAERSPPAVGPSSPVPAFSGDRFSTLAKLAVSGRSQAKASHELTSFYMSDSSPEAHAPAMTLQMPHLPVTAVTRISEKFSGENIHSAGTTNASTGLLGQNQSKNEMTLKTSNQSVNATSVTKPVSTASYEASSGNKTGESAADSYCGMTPKAHSSPPTVHRQVERRRELVRSQTLPRTTGTQARKALFEKFEQDSGKGKGQSRAKLKRSQSFGVASASSIKQILLDWCRSKTIGYKHIDLQNFSSSWNDGMAFCALVHSFFPESFDYNKLDPANRKQNFELAFTMAEKMAHCDRLIEVDDMMMMGHKPDPMCVFTYVQSLYNHLRHFE", "length": 427, "header": "tr|A0A8V1AHD4-1|A0A1D5PRI5_CHICK Computationally mapped isoform of Smoothelin like 2 OS=Gallus gallus OX=9031 GN=SMTNL2 PE=3 SV=1 CANONICAL=A0A1D5PRI5-1" }, "locus": { "chromosome": "19", "start_pos": 10416471, "end_pos": 10395297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070872.1", "url": "https://www.ensembl.org/id/ENSGALT00010070872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043563.1", "url": "https://www.ensembl.org/id/ENSGALP00010043563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417687", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417687", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUC1-1", "protein_name": "Smoothelin-like 2", "gene_name": "Smtnl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPTPDAEEAHTVREALGRYEAALEGAVRALHEDMQGLQRGVERRVAEALRLAGPLARTVAELQRDNQRLQAQLERLTRQVEALGLATGVSPAPGTPSPPPATTVTDRAPRLGTARFSSHATFSLSGRSPSMEHDEVSDLEARRTSNSCIMENGHQLDAGSANGSSEVQASSAQESPRPRPVSLSLRLPHQPVTAVTRVSEKFSGETSASALSPTSAAIVGGFTPSPSEAISPWTPSPTEKSSSFTRSLSGSGYGAVTAGKRKDSPPLVTPPQSPPSSQPPAMTQAPRQGERRRELVRSQTLPRTSGAQARKALFEKWEQDTASKGKGETRAKLKRSQSFGVASASSIKQILLEWCRSKTVGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNALSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE", "length": 456 }, "evidence": [ { "id": "A0A1D5PRI5", "url": "https://omabrowser.org/oma/group/A0A1D5PRI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RGN8-1", "protein_name": "Smoothelin like 2", "gene_name": "SMTNL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPAPDAEEARTVREALGRYEAALEGAVRALHEDMQGLQRGVEQRVAEALRLAGPLARTVAELQRDNQRLQAQLERLTRQVEALGLATGMAPTPGTPSPPPAPSVPDRAPRLGTARFASHATFSLSGRSQSVDQHDEASGSETRRTSNSCIFENGHQPGAGLGDGPPEAPQTIPAPEPPKPRPVSLSLRLPHQPVTAVTRVSERFSGETSATALSATSAAKLGSPSEATTPWTPSPSEKNSSLSRSLSTLTASRNNDSSPPLVTPPQSPPSPQPPATTQAHRQGERRRELVRSQTLPRTSGAQARKALFEKWEQDTAGKGRSETRAKLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNALSPTQRRQNFELAFTMAENLANCERLIEVEDMMLMGRKPDPMCVFTYVQSLYNHLRRFE", "length": 450 }, "evidence": [ { "id": "A0A1D5PRI5", "url": "https://omabrowser.org/oma/group/A0A1D5PRI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2KI85-1", "protein_name": "Smoothelin-like protein 2", "gene_name": "SMTNL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESAPDAEEARTVREALGRYEAALEGAVRALHEDMQGLQRGVEQRVAEALRLAGPLARTVAELQRDNQRLQTQLERLTRQVESLGLTTGLAPAPGTPSPPPAPGVPNRAPRLGTARFASHATFSLSGRSQSLDHHDEASELEMRRTSNSCIIENGHQPGADPGDGPPEATQTIPAPEPPKPRPVSLSLRLPHQPVTAVTRVSERFSGETSATALSPTSAAILGGLSSSPSEATTPWTPSPSEKNSSLPRSLSSSGFGAMTASRNNNSPPLVTPPQSPPSPQPPATTQAHRPGERRRELVRSQTLPRTSGAQARKALFEKWEQDTAGKGKGETRAKLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNALSPTQRRQNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE", "length": 458 }, "evidence": [ { "id": "A0A1D5PRI5", "url": "https://omabrowser.org/oma/group/A0A1D5PRI5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2TAL5-1", "protein_name": "Smoothelin-like protein 2", "gene_name": "SMTNL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAMRLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSNSCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAITRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRRELVRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE", "length": 461 }, "evidence": [ { "id": "A0A1D5PRI5", "url": "https://omabrowser.org/oma/group/A0A1D5PRI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CI12-1", "protein_name": "Smoothelin-like protein 2", "gene_name": "Smtnl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSPDAEEAHTVREALGRYEAALEGAVRALHEDMQGLQRGVERRVAEALRLAGPLARTVAELQRDNQRLQAQLERLTRQVEALGLATGVSPAPGTPSPPPAATVTDRAPRLGTARFSSHATFSLSGRSPSVEHDEASDLEVRRASNSCILENGHQLDAGPANGSSEVQTSSAQEPPRPRPVSLSLRMPHQPVTAVTRVSEKFSGETSASALSPTSAAIVGGFTPSPSEAISPWTPSPTEKSSSFTRSLSGSGYGAVTAGKRKDSPPLVTPPQSPPSSQPPAMTQAPRQGERRRELVRSQTLPRTSGAQARKALFEKWEQDTASKGKGETRAKLKRSQSFGVASASSIKQILLEWCRSKTVGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNALSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE", "length": 456 }, "evidence": [ { "id": "A0A1D5PRI5", "url": "https://omabrowser.org/oma/group/A0A1D5PRI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRI5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PRI5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 468, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PRI5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRI5" } ], "lectin_list": [], 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PRJ7-1", "uniprot_ac": "A0A1D5PRJ7", "uniprot_id": "A0A1D5PRJ7_CHICK", "mass": { "chemical_mass": 28427.0, "monoisotopic_mass": 28427.0 }, "refseq": { "ac": "NP_001026146", "name": "protein FAM133", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146" }, "gene_names": [ { "name": "FAM133B", "type": "recommended", "evidence": [ { "id": "A0A1D5PRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7" } ] }, { "name": "FAM133B", "type": "synonym", "evidence": [ { "id": "NP_001026146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146" } ] }, { "name": "FAM133", "type": "synonym", "evidence": [ { "id": "NP_001026146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 133 member B", "type": "synonym", "evidence": [ { "id": "A0A1D5PRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7/entry#names_and_taxonomy" } ] }, { "name": "protein FAM133", "type": "synonym", "evidence": [ { "id": "NP_001026146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719706.1, SRR13267652.23638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992660 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000036.1. On Sep 23, 2021 this sequence version replaced NP_001026146.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM133B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7", "locus": { "chromosome": "2", "start_pos": 22587545, "end_pos": 22604109, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004991", "url": "https://www.ensembl.org/id/ENSGALG00010004991" } ] } } ], "crossref": [ { "id": "A0A1D5PRJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009475", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009475", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420557", "url": "https://www.ncbi.nlm.nih.gov/gene/420557", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420557", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420557", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPTWDDL", "url": "https://omabrowser.org/oma/group/RPTWDDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PRJ7", "url": "https://www.orthodb.org/?gene=A0A1D5PRJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEK5", "url": "https://www.orthodb.org/?gene=A0A8V0XEK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31911:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31911:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001026146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKRDNRVAYMNPIAMARARGPAQNSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSRALAEFEEKMNENWKKELEKHREKLLGGNESSSKKKEKKKKEKKKSSRLSSSSSSSSSSDSSSSASDSEDEDKKQGKKKKKKKHRSSRKSSSSSASESESDSKDSTKKKKSKEEHEKEKDGKNHHRKRKKADRGDGPLSSESLSEPDQTEEVQVKKKKSNEEKEKATDKAKKRKKHKKHSKKKKKKAAGSNSDLE", "length": 250, "header": "tr|A0A1D5PRJ7-1|A0A1D5PRJ7_CHICK Isoform 1 of Family with sequence similarity 133 member B OS=Gallus gallus OX=9031 GN=FAM133B PE=3 SV=2 CANONICAL=A0A1D5PRJ7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRJ7/entry", "sequence": { "sequence": "MGKRDNRVAYMNPIAMARARGPAQNSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSRALAEFEEKMNENWKKELEKHREKLLGGNESSSKKKEKKKKEKKKSSRLSSSSSSSSSSDSSSSASDSEDEDKKQGKKKKKKKHRSSRKSSSSSASESESDSKDSTKKKKSKEEHEKEKDGKNHHRKRKKADRGDGPLSSESLSEPDQTEEVQVKKKKSNEEKEKATDKAKKRKKHKKHSKKKKKKAAGSNSDLE", "length": 250, "header": "tr|A0A1D5PRJ7-1|A0A1D5PRJ7_CHICK Isoform 1 of Family with sequence similarity 133 member B OS=Gallus gallus OX=9031 GN=FAM133B PE=3 SV=2 CANONICAL=A0A1D5PRJ7-1" }, "locus": { "chromosome": "2", "start_pos": 22603986, "end_pos": 22589723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011728.1", "url": "https://www.ensembl.org/id/ENSGALT00010011728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006569.1", "url": "https://www.ensembl.org/id/ENSGALP00010006569.1" } ] } }, { "isoform_ac": "A0A8V0XEK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK5/entry", "sequence": { "sequence": "MGKRDNRVAYMNPIAMARARGPAQNSGPTIQDYLNRPRPTCSASDSEDEDKKQGKKKKKKKHRSSRKSSSSSASESESDSKDSTKKKKSKEEHEKEKVQVKKKKSNEEKEKATDKAKKRKKHKKHSKKKKKKAAGSNSDLE", "length": 141, "header": "tr|A0A8V0XEK5-1|A0A1D5PRJ7_CHICK Computationally mapped isoform of Family with sequence similarity 133 member B OS=Gallus gallus OX=9031 GN=FAM133B PE=3 SV=1 CANONICAL=A0A1D5PRJ7-1" }, "locus": { "chromosome": "2", "start_pos": 22603986, "end_pos": 22589723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011722.1", "url": "https://www.ensembl.org/id/ENSGALT00010011722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006567.1", "url": "https://www.ensembl.org/id/ENSGALP00010006567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420557", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420557", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5BKY9-1", "protein_name": "Protein FAM133B", "gene_name": "FAM133B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKRDNRVAYMNPIAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP", "length": 247 }, "evidence": [ { "id": "A0A1D5PRJ7", "url": "https://omabrowser.org/oma/group/A0A1D5PRJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CVI2-1", "protein_name": "Protein FAM133B", "gene_name": "Fam133b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKRDNRVAYMNPIAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGNESSSKKRQKKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQTKRRKKKKSRCHKSPESSGSDSASDSKDGSKKKKKSKDVTEREKDTKGLSKKRKMYEDKPLSSESLSESDCGEVQAKRKKSGEERERTTDKAKKRRKHKKHSKKKKKKAASSSSDSP", "length": 245 }, "evidence": [ { "id": "A0A1D5PRJ7", "url": "https://omabrowser.org/oma/group/A0A1D5PRJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PRJ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 250, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PRJ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRJ7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PRN8-1", "uniprot_ac": "A0A1D5PRN8", "uniprot_id": "A0A1D5PRN8_CHICK", "mass": { "chemical_mass": 53335.0, "monoisotopic_mass": 53335.0 }, "refseq": {}, "gene_names": [ { "name": "DAPK3", "type": "recommended", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DAPK3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8", "locus": {} } ], "crossref": [ { "id": "A0A1D5PRN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PRN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037733", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037733", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14105", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748881", "url": "https://www.ncbi.nlm.nih.gov/gene/101748881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748881", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748881", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PRN8", "url": "https://www.orthodb.org/?gene=A0A1D5PRN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTFRQESVEDFYEMGEELGSGQFAIVRKCRERKTGVEYAAKFIKKRRLSSSRRGVSREEIEREVDILREIQHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEEEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKKRMTIAQSLEHPWIKVIKRRNVRNEDSGKKAEQRRRLKTTRLKEYTIKSHSSMPPNNTYVNFERFSKVMEEVAAAEETLREIQRNKRSFREDIEALLSIYEEKESWYKEENESIGRDLRQIRQELLRAESARQRAQEESRNVMQAAGGLRRRYRRLEKRYGALAEQVASEVRFVQELLWSIEREKLQSGGEDGSIR", "length": 457, "header": "tr|A0A1D5PRN8-1|A0A1D5PRN8_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=DAPK3 PE=1 SV=2 CANONICAL=A0A1D5PRN8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8/entry", "sequence": { "sequence": "MSTFRQESVEDFYEMGEELGSGQFAIVRKCRERKTGVEYAAKFIKKRRLSSSRRGVSREEIEREVDILREIQHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEEEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKKRMTIAQSLEHPWIKVIKRRNVRNEDSGKKAEQRRRLKTTRLKEYTIKSHSSMPPNNTYVNFERFSKVMEEVAAAEETLREIQRNKRSFREDIEALLSIYEEKESWYKEENESIGRDLRQIRQELLRAESARQRAQEESRNVMQAAGGLRRRYRRLEKRYGALAEQVASEVRFVQELLWSIEREKLQSGGEDGSIR", "length": 457, "header": "tr|A0A1D5PRN8-1|A0A1D5PRN8_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=DAPK3 PE=1 SV=2 CANONICAL=A0A1D5PRN8-1" }, "locus": { "chromosome": "28", "start_pos": 1891018, "end_pos": 1886653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067384.1", "url": "https://www.ensembl.org/id/ENSGALT00010067384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041215.1", "url": "https://www.ensembl.org/id/ENSGALP00010041215.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:101748881", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748881", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "pmid": "" }, { "name": "myosin light chain kinase activity", "id": "GO:0004687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004687", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PRN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": 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{ "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { 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[ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { 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"https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ] } ], "protein_names": [ { "name": "Heat shock factor protein 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PS43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43/entry#names_and_taxonomy" } ] }, { "name": "heat shock factor protein 3", "type": "synonym", "evidence": [ { "id": "NP_001291970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ] }, { "name": "heat shock transcription factor 1", "type": "synonym", "evidence": [ { "id": "NP_001291970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ] }, { "name": "heat shock transcription factor 3", "type": "synonym", "evidence": [ { "id": "NP_001291970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.8255.1, SRR13267661.14885.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Feb 18, 2015 this sequence version replaced XP_004940584.1. Sequence Note: This RefSeq record was created from transcript data from different strains and from genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ] }, { "annotation": "As well as altering their basal mRNA levels during the first week post-hatch, thermal manipulation also altered the dynamics of the mRNA expression of heat shock factors, which was associated with improved acquisition of thermotolerance during thermal stress.", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" }, { "database": "PubMed", "id": "29917159", "url": "https://glygen.org/publication/PubMed/29917159" } ] }, { "annotation": "Data suggest that exposure to high environmental temperature up-regulates expression of heat shock factor 1 (HSF1) mRNA, HSF3 mRNA, and heat shock protein 70 (HSP70) mRNA/protein in liver, heart, and breast muscle; dietary supplementation with manganese down-regulates expression of HSP70 in breast muscle.", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" }, { "database": "PubMed", "id": "27890044", "url": "https://glygen.org/publication/PubMed/27890044" } ] }, { "annotation": "The expression of HSF3 and HSP70 mRNA in two chicken breeds exhibit species-specific and tissue-specific differences during heat stress. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" }, { "database": "PubMed", "id": "25501188", "url": "https://glygen.org/publication/PubMed/25501188" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSF3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43", "locus": { "chromosome": "4", "start_pos": 238096, "end_pos": 253564, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016823", "url": "https://www.ensembl.org/id/ENSGALG00010016823" } ] } } ], "crossref": [ { "id": "A0A1D5PS43", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS43-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREGSALPGAPGAAPVPGFLAKLWALVEDPQSDDVICWSRNGENFCILDEQRFAKELLPKYFKHNNISSFIRQLNMYGFRKVVALENGMITAEKNSVIEFQHPFFKQGNAHLLENIKRKVSAVRTEDLKVCAEDLHKVLSEVQEMREQQNNMDIRLANMKRENKALWKEVAVLRQKHSQQQKLLSKILQFILSLMRGNYIVGVKRKRSLTDAAGASPSKYSRQYVRIPVESGQAMAFSEHNSDDEDGNRTGLIIRDITDTLENATNGLLAVAHTSGRDRETQTALDPGLPICQVSQPNELSCAEPIPPVHINDVSKPNEMGNVAVELHTAQANAPEDPVSVIDSILNENNSGNQNDPLLDREEIQDFLNCIDASLEELQAMLSGKQYSFGSEAFSDVFNPELPALDMNLMETSPGMENIANMEDSTEDLGASERETAGSKDMQLIQYRANPLLSLFEELPSGEAGGKTEDPKDLLLAPLEEKPALHPPSGSETVLPLAVPANQAEPPVDALGMGDPPLLSEDGNGEYKLFPLLLLSPVANFIEEASEIETS", "length": 551, "header": "tr|A0A1D5PS43-1|A0A1D5PS43_CHICK Isoform 1 of Heat shock factor protein 3 OS=Gallus gallus OX=9031 GN=HSF3 PE=3 SV=1 CANONICAL=A0A1D5PS43-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PS43-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43/entry", "sequence": { "sequence": "MREGSALPGAPGAAPVPGFLAKLWALVEDPQSDDVICWSRNGENFCILDEQRFAKELLPKYFKHNNISSFIRQLNMYGFRKVVALENGMITAEKNSVIEFQHPFFKQGNAHLLENIKRKVSAVRTEDLKVCAEDLHKVLSEVQEMREQQNNMDIRLANMKRENKALWKEVAVLRQKHSQQQKLLSKILQFILSLMRGNYIVGVKRKRSLTDAAGASPSKYSRQYVRIPVESGQAMAFSEHNSDDEDGNRTGLIIRDITDTLENATNGLLAVAHTSGRDRETQTALDPGLPICQVSQPNELSCAEPIPPVHINDVSKPNEMGNVAVELHTAQANAPEDPVSVIDSILNENNSGNQNDPLLDREEIQDFLNCIDASLEELQAMLSGKQYSFGSEAFSDVFNPELPALDMNLMETSPGMENIANMEDSTEDLGASERETAGSKDMQLIQYRANPLLSLFEELPSGEAGGKTEDPKDLLLAPLEEKPALHPPSGSETVLPLAVPANQAEPPVDALGMGDPPLLSEDGNGEYKLFPLLLLSPVANFIEEASEIETS", "length": 551, "header": "tr|A0A1D5PS43-1|A0A1D5PS43_CHICK Isoform 1 of Heat shock factor protein 3 OS=Gallus gallus OX=9031 GN=HSF3 PE=3 SV=1 CANONICAL=A0A1D5PS43-1" }, "locus": { "chromosome": "4", "start_pos": 253424, "end_pos": 240476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040595.1", "url": "https://www.ensembl.org/id/ENSGALT00010040595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023569.1", "url": "https://www.ensembl.org/id/ENSGALP00010023569.1" } ] } }, { "isoform_ac": "A0A8V0YXP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXP9/entry", "sequence": { "sequence": "MREGSALPGAPGAAPVPGFLAKLWALVEDPQSDDVICWSRNGENFCILDEQRFAKELLPKYFKHNNISSFIRQLNMYGFRKVVALENGMITAEKNSVIEFQHPFFKQGNAHLLENIKRKVSAVRTEDLKVCAEDLHKVLSEVQEMREQQNNMDIRLANMKRENKALWKEVAVLRQKHSQQQKLLSKILQFILSLMRGNYIVGVKRKRSLTDAAGASPSKYSRQYVRIPVESGQAMAFSEHNSDDEDGNRTGLIIRDITDTLENATNGLLAVAHTSGRDRETQTALDPGLPICQVSQPNELSCAEPIPPVHINDVSKPNEMGNVAVELHTAQANAPEDPVSVIDSILNENNSGNQNDPLLDREEIQDFLNCIDASLEELQAMLSGKQYSFGSEAFSDVFNPELPALDMNLMETSPDRKHGRQHRRSGSK", "length": 428, "header": "tr|A0A8V0YXP9-1|A0A1D5PS43_CHICK Computationally mapped isoform of Heat shock factor protein 3 OS=Gallus gallus OX=9031 GN=HSF3 PE=3 SV=1 CANONICAL=A0A1D5PS43-1" }, "locus": { "chromosome": "4", "start_pos": 253424, "end_pos": 241418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040589.1", "url": "https://www.ensembl.org/id/ENSGALT00010040589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023566.1", "url": "https://www.ensembl.org/id/ENSGALP00010023566.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Alteration of HSF3 and HSP70 mRNA expression in the tissues of two chicken breeds during acute heat stress.", "journal": "Genetics and molecular research : GMR", "date": "2014-11-27", "authors": "Zhang W W, Kong L N, Zhang X Q, Luo Q B", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ], "reference": [ { "type": "PubMed", "id": "25501188", "url": "https://glygen.org/publication/PubMed/25501188" } ] }, { "title": "Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures.", "journal": "The British journal of nutrition", "date": "2016-12", "authors": "Zhu Yong-Wen, Lu Lin, Li Wen-Xiang, Zhang Li-Yang, Ji Cheng, Lin Xi, Liu Hsiao-Ching, Odle Jack, Luo Xu-Gang", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ], "reference": [ { "type": "PubMed", "id": "27890044", "url": "https://glygen.org/publication/PubMed/27890044" } ] }, { "title": "Thermal manipulation during broiler chicken embryogenesis increases basal mRNA levels and alters production dynamics of heat shock proteins 70 and 60 and heat shock factors 3 and 4 during thermal stress.", "journal": "Poultry science", "date": "2018-10-01", "authors": "Al-Zghoul M B", "evidence": [ { "database": "RefSeq", "id": "NP_001291970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291970" } ], "reference": [ { "type": "PubMed", "id": "29917159", "url": "https://glygen.org/publication/PubMed/29917159" } ] } ], "pathway": [ { "id": "gga:422169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422169", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS43" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS43", "url": 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"name": "LSM family member 14B", "type": "synonym", "evidence": [ { "id": "A0A1D5PS81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS81/entry#names_and_taxonomy" } ] }, { "name": "protein LSM14 homolog B isoform X5", "type": "synonym", "evidence": [ { "id": "XP_015152151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152151" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152151" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS81", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LSM14B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS81", "locus": { "chromosome": "20", "start_pos": 8076941, "end_pos": 8064196, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022801", "url": "https://www.ensembl.org/id/ENSGALG00010022801" } ] } } ], "crossref": [ { "id": "A0A1D5PS81", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS81", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZRX9/entry", "sequence": { "sequence": "MSSGTPYIGSKISLISKAQIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASTSSFQPHVPYSPFRGMPPYSQLAASSLLSQQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSEPDMSSEPHQLSSKGAGFPSVHPVRKSPMVEQAVQTGPVDNINSQKPLPVKVTPGVQRNGRQVPQSSTKAADAVPATPVQTQGQVNDENRRPQRRRSGNRGNRRTRNRSRGQNRPTTVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAETEEEKGDPGVATQNNDGNAEEDLLGPNCYYDKSKSFFDNISSELKSSSRRTTWAEERKLNTETFGVSGRFLRGRSFRGGFRGGRGSGAARRNQTTHRAGTGRV", "length": 427, "header": "tr|A0A8V0ZRX9-1|A0A8V0ZRX9_CHICK Computationally mapped isoform of LSM family member 14B OS=Gallus gallus OX=9031 GN=LSM14B PE=1 SV=1 CANONICAL=A0A1D5PS81-1" }, "locus": { "chromosome": "20", "start_pos": 8075260, "end_pos": 8064312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055447.1", "url": "https://www.ensembl.org/id/ENSGALT00010055447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033578.1", "url": "https://www.ensembl.org/id/ENSGALP00010033578.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001008676" } ] }, { "name": "interferon receptor", "type": "synonym", "evidence": [ { "id": "NP_001008676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676" } ] }, { "name": "second chain of IFN-gamma receptor", "type": "synonym", "evidence": [ { "id": "NP_001008676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY957508.1, AY820753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000020.1. On Sep 23, 2021 this sequence version replaced NP_001008676.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676" } ] }, { "annotation": "IFNGR-2 is localized on chromosome 1 of chicken in tandem with IFNAR-1, interleukin- 10 receptor (IL-10R-2), and IFNAR-2", "evidence": [ { "database": "RefSeq", "id": "NP_001008676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676" }, { "database": "PubMed", "id": "16800782", "url": "https://glygen.org/publication/PubMed/16800782" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFNGR2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87", "locus": { "chromosome": "1", "start_pos": 105405282, "end_pos": 105396793, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012077", "url": "https://www.ensembl.org/id/ENSGALG00010012077" } ] } } ], "crossref": [ { "id": "A0A1D5PS87", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032660", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418502", "url": "https://www.ncbi.nlm.nih.gov/gene/418502", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418502", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418502", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WATVPWF", "url": "https://omabrowser.org/oma/group/WATVPWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PS87", "url": "https://www.orthodb.org/?gene=A0A1D5PS87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-877300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-877312", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877312", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9732724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001008676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PS87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PS87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPWRPLLLFLVGIFLLGPARAPGTEASPHLPAPEDVMVYSFNFCNSLRWSPVKVDGGSVSYTVQFKTGAFNHWSEMNCTRITQTECSFLKSVKERRWTVVLRVRAEMGPRTSAWVETDPFVAERNTTIGPPKVNSVIVSSDSLLISVTPPFGPEPGYHLQYHVSYWENTTITTKKEIKTSNTLFKIKDLKQSTLYCFTIQIELMTYSRFHLIGLQTVPECYRTTISEATKAGYIVAIFMSVGLLLIVIIVGFFCLWRNQKAIKYLSQPPLRIPSHFEEYLRDPSMPQLEVLENHDEDPQDLLTVVYTGEGSSAYGDMLDGNTCSHSSSSSRDVT", "length": 334, "header": "tr|A0A1D5PS87-1|A0A1D5PS87_CHICK Isoform 1 of Interferon gamma receptor 2 (interferon gamma transducer 1) OS=Gallus gallus OX=9031 GN=IFNGR2 PE=4 SV=1 CANONICAL=A0A1D5PS87-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PS87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87/entry", "sequence": { "sequence": "MPWRPLLLFLVGIFLLGPARAPGTEASPHLPAPEDVMVYSFNFCNSLRWSPVKVDGGSVSYTVQFKTGAFNHWSEMNCTRITQTECSFLKSVKERRWTVVLRVRAEMGPRTSAWVETDPFVAERNTTIGPPKVNSVIVSSDSLLISVTPPFGPEPGYHLQYHVSYWENTTITTKKEIKTSNTLFKIKDLKQSTLYCFTIQIELMTYSRFHLIGLQTVPECYRTTISEATKAGYIVAIFMSVGLLLIVIIVGFFCLWRNQKAIKYLSQPPLRIPSHFEEYLRDPSMPQLEVLENHDEDPQDLLTVVYTGEGSSAYGDMLDGNTCSHSSSSSRDVT", "length": 334, "header": "tr|A0A1D5PS87-1|A0A1D5PS87_CHICK Isoform 1 of Interferon gamma receptor 2 (interferon gamma transducer 1) OS=Gallus gallus OX=9031 GN=IFNGR2 PE=4 SV=1 CANONICAL=A0A1D5PS87-1" }, "locus": { "chromosome": "1", "start_pos": 105404255, "end_pos": 105396978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028938.1", "url": "https://www.ensembl.org/id/ENSGALT00010028938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016697.1", "url": "https://www.ensembl.org/id/ENSGALP00010016697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A novel gene of beta chain of the IFN-gamma receptor of Huiyang chicken: cloning, distribution, and CD assay.", "journal": "Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research", "date": "2006-07", "authors": "Han Chun-Lai, Zhang Wei, Dong Hai-Tao, Han Xue, Wang Ming", "evidence": [ { "database": "RefSeq", "id": "NP_001008676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008676" } ], "reference": [ { "type": "PubMed", "id": "16800782", "url": "https://glygen.org/publication/PubMed/16800782" } ] } ], "pathway": [ { "id": "gga:418502", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418502", "resource": "KEGG Pathway" }, { "id": "R-GGA-877300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877300", "resource": "Reactome", "description": "Interferon gamma signaling" }, { "id": "R-GGA-877312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877312", "resource": "Reactome", "description": "Regulation of IFNG signaling" }, { "id": "R-GGA-9732724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9732724", "resource": "Reactome", "description": "IFNG signaling activates MAPKs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B963-1", "protein_name": "Interferon gamma receptor 2", "gene_name": "IFNGR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPLLVLLPLVLPPLLLFGRCGAAASPADAPPQLPPPQNLKVRLYNAQQALSWDPVTLSNDTRPVVYQVQYRYSTSHNWYDVNKRDSSVDCTNLSRTECDFTANSLSKGFPRQFNISLRVRAKLGDRVSPWVTAPWFEHYRNATIGPPENIWVTPEEGSLIIRFSSPFDVPASVAFFSYYVYYREMAGIQQVTQPFRNNFITLNDLKPLRVYCFQVKAELFLVKENISRSGHLSNISCSETTADASTKLQQVILIAVGTFLLLLVVVGACLFLVLKFRGLVKYWFHSPPRIPVQIEEYLKDPAQPILDALDKDSSSRDDAWDSVSIVSFPENHREDTLQSTLTQSTVSSHKPMDGAPSANTAADVSVPV", "length": 369 }, "evidence": [ { "id": "A0A1D5PS87", "url": "https://omabrowser.org/oma/group/A0A1D5PS87/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A109-1", "protein_name": "Interferon gamma receptor 2", "gene_name": "Ifngr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPPPLWLPLLLLCGLGAAVSSPDSLSQLAAPRKLKLHLYNDEQMLSWEPSPSSNDTRPVVYQVEYSYVDGSWHRLREPNCTDIAETKCDFTGGGRLKVFPYSYTVFLRVRARLGKHTSHWVKLDPFQHYENVTVGPPKNISVTPGKGSLVIHFSPPFDVVQEASFQYFVHYWEKTETQKVKGPYKSNSIVLDDLKPFRVYCLQTKAQLILKNRNIGPHGLLSNVSCHETTADASTSLQQVILILFGIFMLLLALTGACFILFLRYQSRVKYWFQAPPDIPEQIKEYLKDPDQLILEALDKDGSPKDEAWDSVSIISSPEKEQDDVLQIP", "length": 330 }, "evidence": [ { "id": "A0A1D5PS87", "url": "https://omabrowser.org/oma/group/A0A1D5PS87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38484-1", "protein_name": "Interferon gamma receptor 2", "gene_name": "IFNGR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL", "length": 337 }, "evidence": [ { "id": "A0A1D5PS87", "url": "https://omabrowser.org/oma/group/A0A1D5PS87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63953-1", "protein_name": "Interferon gamma receptor 2", "gene_name": "Ifngr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPLPLWLPSLLLCGLGAAASSPDSFSQLAAPLNPRLHLYNDEQILTWEPSPSSNDPRPVVYQVEYSFIDGSWHRLLEPNCTDITETKCDLTGGGRLKLFPHPFTVFLRVRAKRGNLTSKWVGLEPFQHYENVTVGPPKNISVTPGKGSLVIHFSPPFDVFHGATFQYLVHYWEKSETQQEQVEGPFKSNSIVLGNLKPYRVYCLQTEAQLILKNKKIRPHGLLSNVSCHETTANASARLQQVILIPLGIFALLLGLTGACFTLFLKYQSRVKYWFQAPPNIPEQIEEYLKDPDQFILEVLDKDGSPKEDSWDSVSIISSPEKERDDVLQTP", "length": 332 }, "evidence": [ { "id": "A0A1D5PS87", "url": "https://omabrowser.org/oma/group/A0A1D5PS87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PS87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PS87-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 334, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PS87-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PS87" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PTV5-1", "uniprot_ac": "A0A1D5PTV5", "uniprot_id": "A0A1D5PTV5_CHICK", "mass": { "chemical_mass": 63205.0, "monoisotopic_mass": 63205.0 }, "refseq": { "ac": "XP_416441", "name": "transmembrane 7 superfamily member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416441" }, "gene_names": [ { "name": "TM7SF3", "type": "recommended", "evidence": [ { "id": "A0A1D5PTV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ] }, { "name": "TM7SF3", "type": "synonym", "evidence": [ { "id": "XP_416441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416441" } ] } ], "protein_names": [ { "name": "Transmembrane 7 superfamily member 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PTV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 7 superfamily member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416441" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416441.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416441" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TM7SF3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5", "locus": { "chromosome": "1", "start_pos": 68081034, "end_pos": 68099013, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014839", "url": "https://www.ensembl.org/id/ENSGALG00010014839" } ] } } ], "crossref": [ { "id": "A0A1D5PTV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PTV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014085", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014085", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418215", "url": "https://www.ncbi.nlm.nih.gov/gene/418215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VCTWYLQ", "url": "https://omabrowser.org/oma/group/VCTWYLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PTV5", "url": "https://www.orthodb.org/?gene=A0A1D5PTV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15937:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15937:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFPPGAVLLLGLLGALLGGGASGLLELSLGKFRNVLLNQTNPVEAVIRNIASNVTVIIFQVHAQQSDVVISFDKNPSTNSSGTGVDRGLISILRPQQTVCTWYLRSLDANQVLSTAISIPYMEKDPIPGGCNLEFDLEVDPNIYLDYTLVDVRIKFAPANLGYMRGANPPSCDSGTGQNSRWRLRYDVYQYFLPENNLSEMVLMNHIRKMSEVQSIKANGVKMLTVTSDDKTDVYFSSLPGQGVIYNVIVWDPLWNTSAAYIPVHTYACSFADLVDNCSSLSKLSTKMFFTALAVLGLFTCFFGHRFWKTDLFFMGFIFTGFFFFVFITRVTGLGYDVRLVLTAVAGITGGILLVACWWRFGSVLLCMLIIGLVLGFLFSSMVFFTPLGDYRVFRDDVVFWVTFSSVALMIPVLFVGCPRILNILACGIVGSYSVVLAIACYVYTSLAYIALDLLRRILNDYFSRAYTNVPFQTNDFIVLAVWIMLALSGVTMQLRRERSEVPFPPHPYLTWKRERERRSTNVLDPSHHIPPLRERIHSKLLQIKELFQKEQPAGERTPLLL", "length": 563, "header": "tr|A0A1D5PTV5-1|A0A1D5PTV5_CHICK Isoform 1 of Transmembrane 7 superfamily member 3 OS=Gallus gallus OX=9031 GN=TM7SF3 PE=4 SV=3 CANONICAL=A0A1D5PTV5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PTV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5/entry", "sequence": { "sequence": "MRFPPGAVLLLGLLGALLGGGASGLLELSLGKFRNVLLNQTNPVEAVIRNIASNVTVIIFQVHAQQSDVVISFDKNPSTNSSGTGVDRGLISILRPQQTVCTWYLRSLDANQVLSTAISIPYMEKDPIPGGCNLEFDLEVDPNIYLDYTLVDVRIKFAPANLGYMRGANPPSCDSGTGQNSRWRLRYDVYQYFLPENNLSEMVLMNHIRKMSEVQSIKANGVKMLTVTSDDKTDVYFSSLPGQGVIYNVIVWDPLWNTSAAYIPVHTYACSFADLVDNCSSLSKLSTKMFFTALAVLGLFTCFFGHRFWKTDLFFMGFIFTGFFFFVFITRVTGLGYDVRLVLTAVAGITGGILLVACWWRFGSVLLCMLIIGLVLGFLFSSMVFFTPLGDYRVFRDDVVFWVTFSSVALMIPVLFVGCPRILNILACGIVGSYSVVLAIACYVYTSLAYIALDLLRRILNDYFSRAYTNVPFQTNDFIVLAVWIMLALSGVTMQLRRERSEVPFPPHPYLTWKRERERRSTNVLDPSHHIPPLRERIHSKLLQIKELFQKEQPAGERTPLLL", "length": 563, "header": "tr|A0A1D5PTV5-1|A0A1D5PTV5_CHICK Isoform 1 of Transmembrane 7 superfamily member 3 OS=Gallus gallus OX=9031 GN=TM7SF3 PE=4 SV=3 CANONICAL=A0A1D5PTV5-1" }, "locus": { "chromosome": "1", "start_pos": 68098136, "end_pos": 68083111, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035710.1", "url": "https://www.ensembl.org/id/ENSGALT00010035710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020718.1", "url": "https://www.ensembl.org/id/ENSGALP00010020718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1QC74-1", "protein_name": "Transmembrane 7 superfamily member 3", "gene_name": "tm7sf3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLKRECLVLLVLSWVGSLRAQDENRVVFSLGTFQNVSIPVNGTVQAVVSRIPADVSFITLQFHTQHRNVTLSYLQEPLFGFFVTAEDAGLLSTLIPSQFSISWFLNTPDGSSAAAIGVILPYTSTDPVPGACNQEFPMEIDPNIYLKYNLFETTITFAPANLGYGRGEIPPACDVQTDSSTRWRLVYEVYQFFLPEGDQSEQSLISSMERVANVQNVQDNSRKVVSLSSQEKTQFSFMSLPGQGVIFSVIVRDPVLNTSASYIPVHTYACSFNSTLDGCQDLDKVSTKVFFTVLGLAGLFVCFVGHRFFKCELFGMGFGFMAFLFFVLITRTTTLDYNIRLALTALMGVVGGVVLVMSWWRFGSVLACVLVVGLILGFLISSVVFFTPLGDLPVFHNDVVFWVVFVCIIVVVPLFFIRWPREGNIMTCGVVGAYTVVLAVNAYTYTSLSYITLDVLKRFLNHNFSRAFISVPLQDIDFVMITVWVVLGVSGIIVQLYREKSRPFFPPSPYVLWRQERERRKTNVLDPSYHKPSLPAQIMGRIRQLTRRAEPAGETTPLLL", "length": 561 }, "evidence": [ { "id": "A0A1D5PTV5", "url": "https://omabrowser.org/oma/group/A0A1D5PTV5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5FVF4-1", "protein_name": "Transmembrane 7 superfamily member 3", "gene_name": "Tm7sf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWRLRLLVLAVLAAGSAEAQANSSDGFLEFSVGKFTYFVLSRRFPQEAVLRHISSNVTFLLFQIHSQYQNTTVSYTKTLLPSTSGTGNDRGLVFILRPEQTVCTWYLETEDTKPVQSVAVTLSYSERDPIPGGCNLEFDLDIDPNIYLDYNFFETTIKFAPANIGYARAAEPPPCDVSTGQESRWRLRYHVYQYFLPEGDLTEASLLQHLQRMAQVVQVMASAVKVVTLTADDKTVVSFSSLPGQGVIYNVIVWDPSLNTSAAYVPVHTYACSFDSVDGNCVPPGRVSTKVFSTLFALLGLFTCFFGHRFWKTELFFVGFIFLGFFFYILITRLTALKYEVRLVLTAVAGSIGGLLLVASWWRFGILTLCMLCVGLVLGFLVSSGTFFTPLGNLNVFHDDGVFWVTFSCIALLVPVIFLGCLRILNILACGIVGSYSVVLAINSYMFTSLSYITLNVLRRALNADFRGAFIRVPFQTNDYIILAVWGMLAVTGITLQIRRERGRPPFPPHPYKLWKQERERRVTNILDPSHHIPPLRERLYGWVARIKELFQKEQPAGERTPLLL", "length": 565 }, "evidence": [ { "id": "A0A1D5PTV5", "url": "https://omabrowser.org/oma/group/A0A1D5PTV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CRG1-1", "protein_name": "Transmembrane 7 superfamily member 3", "gene_name": "Tm7sf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRLRLLVLAVLAAGSAEAQANSSDGFLEFSVGKFTYFVLSKSSPQEAVLRHISSNVTFLLFQIHSQYQNTTVSFTKTLLPSTSGTGNDRGLVFILRPEQAVCTWYLETGDTKPVQSVALTLSYSERDPIPGGCNLEFDLDIDPNLYLDYNFFETTIKFAPANIGYARATEPPPCDVSTSRESRWRLRYDVYQYFLPEGDLTEASLLHHLQRMAQVAQVKASAIKVATLTADDKTAVSFSSLPGQGVIYNVIVWDPSLNTSAAYVPVHTYACSFESVDGNCASPGRVSTKVFSTLFALLGLFVCFFGHRFWKTDLFFVGFIFLGFFFYILITRLTPLQYDVRLALTAVAGSFGGLLLVASWWRFGILTLCMLCVGLVLGFLVSSGTFFTPLGNLNVFHDDGVFWVTFSCIALLVPVIFMGCLRILNILACGVVGSYSVVLAVNSYMFTSLSYITLNVLRRALNTDFRGAFIRVPFQTNDYIILAVWGMLAVSGITLQIRRERGQPPFPPHPYKLWKQERERRVTNILDPSHHIPPLRERLYGRVARIKELFQKEQPAGERTPLLL", "length": 565 }, "evidence": [ { "id": "A0A1D5PTV5", "url": "https://omabrowser.org/oma/group/A0A1D5PTV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NS93-1", "protein_name": "Transmembrane 7 superfamily member 3", "gene_name": "TM7SF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFLQLLVVAVLASEHRVAGAAEVFGNSSEGLIEFSVGKFRYFELNRPFPEEAILHDISSNVTFLIFQIHSQYQNTTVSFSPTLLSNSSETGTASGLVFILRPEQSTCTWYLGTSGIQPVQNMAILLSYSERDPVPGGCNLEFDLDIDPNIYLEYNFFETTIKFAPANLGYARGVDPPPCDAGTDQDSRWRLQYDVYQYFLPENDLTEEMLLKHLQRMVSVPQVKASALKVVTLTANDKTSVSFSSLPGQGVIYNVIVWDPFLNTSAAYIPAHTYACSFEAGEGSCASLGRVSSKVFFTLFALLGFFICFFGHRFWKTELFFIGFIIMGFFFYILITRLTPIKYDVNLILTAVTGSVGGMFLVAVWWRFGILSICMLCVGLVLGFLISSVTFFTPLGNLKIFHDDGVFWVTFSCIAILIPVVFMGCLRILNILTCGVIGSYSVVLAIDSYWSTSLSYITLNVLKRALNKDFHRAFTNVPFQTNDFIILAVWGMLAVSGITLQIRRERGRPFFPPHPYKLWKQERERRVTNILDPSYHIPPLRERLYGRLTQIKGLFQKEQPAGERTPLLL", "length": 570 }, "evidence": [ { "id": "A0A1D5PTV5", "url": "https://omabrowser.org/oma/group/A0A1D5PTV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of insulin secretion", "id": "GO:0032024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032024", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" }, { "name": "cellular response to unfolded protein", "id": "GO:0034620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034620", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PTV5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PTV5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 563, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PTV5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PTV5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PTV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" }, { "id": "PF13886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM7S3/TM198-like", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 496, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PTV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTV5" }, { "id": "PF25992", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25992" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM7SF3-like N-terminal immunoglobulin-like", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 122, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PWW3-1", "uniprot_ac": "A0A1D5PWW3", "uniprot_id": "A0A1D5PWW3_CHICK", "mass": { "chemical_mass": 37356.0, "monoisotopic_mass": 37356.0 }, "refseq": { "ac": "NP_001264435", "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264435" }, "gene_names": [ { "name": "HSD17B7", "type": "recommended", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "name": "HSD17B7", "type": "synonym", "evidence": [ { "id": "NP_001264435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264435" } ] } ], "protein_names": [ { "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "type": "recommended", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.210", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.270", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.62", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "17-beta-hydroxysteroid dehydrogenase 7", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001264435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264435" } ] }, { "name": "3-keto-steroid reductase", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "Dihydrotestosterone oxidoreductase", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] }, { "name": "Estradiol 17-beta-dehydrogenase 7", "type": "synonym", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01008913.1, HAEL01000894.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Sep 23, 2021 this sequence version replaced NP_001264435.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264435" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSD17B7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3", "locus": { "chromosome": "8", "start_pos": 3807060, "end_pos": 3812949, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012978", "url": "https://www.ensembl.org/id/ENSGALG00010012978" } ] } } ], "crossref": [ { "id": "A0A1D5PWW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PWW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037852", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037852", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424367", "url": "https://www.ncbi.nlm.nih.gov/gene/424367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424367", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHNIDGY", "url": "https://omabrowser.org/oma/group/WHNIDGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PTW3", "url": "https://www.orthodb.org/?gene=A0A1D5PTW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWW3", "url": "https://www.orthodb.org/?gene=A0A1D5PWW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHX0", "url": "https://www.orthodb.org/?gene=A0A8V0YHX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44442:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44442:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807047", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807062", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16297", "url": "https://www.rhea-db.org/rhea/16297", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18409", "url": "https://www.rhea-db.org/rhea/18409", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24616", "url": "https://www.rhea-db.org/rhea/24616", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "33459", "url": "https://www.rhea-db.org/rhea/33459", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34787", "url": "https://www.rhea-db.org/rhea/34787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "36379", "url": "https://www.rhea-db.org/rhea/36379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46832", "url": "https://www.rhea-db.org/rhea/46832", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46852", "url": "https://www.rhea-db.org/rhea/46852", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PTW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVVLVTGASGGVGLALCRRLLGEDGRIHLCLACRNAQKAEATRDLVLQEYPAAQVSTVEVDLGNLASVLRAAQELRCRFQHLDFVYLNAGIMPNPHVNFKALWKGLLTGRLLHMLTTAEGVMTQTDRLNGDGLQEVFTTNLFGHFILIRQLESLLCGNEKPSRLIWTSSSNARESAFSLSDYQHAKGQESYSSSKYATDLTSVVLNRKFNKQGLYSSVVCPGLVMSNMTFKILPVFLWVLLMPIMFLIRFFAKTYTLTPYNGAEAHVWLFKQKPEYLDPLVKYHSCTSGLGKNFVEPRKLDVDEETAEKFYQKLLELEGQTLEKYGDLLD", "length": 332, "header": "tr|A0A1D5PWW3-1|A0A1D5PWW3_CHICK Isoform 1 of 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 OS=Gallus gallus OX=9031 GN=HSD17B7 PE=1 SV=1 CANONICAL=A0A1D5PWW3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PTW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTW3/entry", "sequence": { "sequence": "MERVVLVTGASGGVGLALCRRLLGEDGRIHLCLACRNAQKAEATRDLVLQEYPAAQVSTVEVDLGNLASVLRAAQELRCRRLLHMLTTAEGVMTQTDRLNGDGLQEVFTTNLFGHFILIRQLESLLCGNEKPSRLIWTSSSNARESAFSLSDYQHAKGQESYSSSKYATDLTSVVLNRKFNKQGLYSSVVCPGLVMSNMTFKILPVFLWVLLMPIMFLIRFFAKTYTLTPYNGAEAHVWLFKQKPEYLDPLVKYHSCTSGLGKNFVEPRKLDVDEETAEKFYQKLLELEGQTLEKYGDLLD", "length": 301, "header": "tr|A0A1D5PTW3-1|A0A1D5PWW3_CHICK Computationally mapped isoform of 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 OS=Gallus gallus OX=9031 GN=HSD17B7 PE=1 SV=1 CANONICAL=A0A1D5PWW3-1" }, "locus": { "chromosome": "8", "start_pos": 3812873, "end_pos": 3807962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031138.1", "url": "https://www.ensembl.org/id/ENSGALT00010031138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018132.1", "url": "https://www.ensembl.org/id/ENSGALP00010018132.1" } ] } }, { "isoform_ac": "A0A1D5PWW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3/entry", "sequence": { "sequence": "MERVVLVTGASGGVGLALCRRLLGEDGRIHLCLACRNAQKAEATRDLVLQEYPAAQVSTVEVDLGNLASVLRAAQELRCRFQHLDFVYLNAGIMPNPHVNFKALWKGLLTGRLLHMLTTAEGVMTQTDRLNGDGLQEVFTTNLFGHFILIRQLESLLCGNEKPSRLIWTSSSNARESAFSLSDYQHAKGQESYSSSKYATDLTSVVLNRKFNKQGLYSSVVCPGLVMSNMTFKILPVFLWVLLMPIMFLIRFFAKTYTLTPYNGAEAHVWLFKQKPEYLDPLVKYHSCTSGLGKNFVEPRKLDVDEETAEKFYQKLLELEGQTLEKYGDLLD", "length": 332, "header": "tr|A0A1D5PWW3-1|A0A1D5PWW3_CHICK Isoform 1 of 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 OS=Gallus gallus OX=9031 GN=HSD17B7 PE=1 SV=1 CANONICAL=A0A1D5PWW3-1" }, "locus": { "chromosome": "8", "start_pos": 3812873, "end_pos": 3807962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031143.1", "url": "https://www.ensembl.org/id/ENSGALT00010031143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018137.1", "url": "https://www.ensembl.org/id/ENSGALP00010018137.1" } ] } }, { "isoform_ac": "A0A8V0YHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX0/entry", "sequence": { "sequence": "MERVVLVTGASGGVGLALCRRLLGEDGRIHLCLACRNAQKAEATRDLVLQEYPAAQVSTVEVDLGNLASVLRAAQELRCRFQHLDFVYLNAGIMPNPHVNFKALWKGLLTGRLLHMLTTAEGVMTQTDRLNGDGLQEVFTTNLFGHFILIRQLESLLCGNEKPSRLIWTSSSNARESAFSLSDYQHAKGQESYSSSKYATDLTSVVLNRKFNKQGLYSSVVCPGLVMSNMTFKILPVFLWVLLMPIMFLVWLFKQKPEYLDPLVKYHSCTSGLGKNFVEPRKLDVDEETAEKFYQKLLELEGQTLEKYGDLLD", "length": 313, "header": "tr|A0A8V0YHX0-1|A0A1D5PWW3_CHICK Computationally mapped isoform of 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 OS=Gallus gallus OX=9031 GN=HSD17B7 PE=1 SV=1 CANONICAL=A0A1D5PWW3-1" }, "locus": { "chromosome": "8", "start_pos": 3812873, "end_pos": 3807962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031141.1", "url": "https://www.ensembl.org/id/ENSGALT00010031141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018135.1", "url": "https://www.ensembl.org/id/ENSGALP00010018135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424367", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424367", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "resource": "Reactome", "description": "Cholesterol biosynthesis via desmosterol (Bloch pathway)" }, { "id": "R-GGA-6807062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807062", "resource": "Reactome", "description": "Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0S8P5-1", "protein_name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "gene_name": "HSD17B7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRKVVLITGASSGVGLALCRRLLKEDDGLHLCLACRNLSKAEAVRASLLASHPDAEVTTVQVDVSSLSSVFRASKELKERFQRLDYVYLNAGIMPNPQLNIKALFCSLFSRKAIHVFSTAEGLLTQNDKITADGLQEVFETNIFGHFILIRELESLLCHSDSPSQLIWTSSRNARKSNFSLEDIQHSKGQEPYSSSKYAIDLLSVALNRKFNQRGLYSSVVCPGTMLTNLTYGILSPFMWMLIMPMIWLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLVKYLSATTGFGSNYVTSKKMDLDEDTAEKCYQNLLELEKHVRVTIKKTDNQS", "length": 334 }, "evidence": [ { "id": "A0A1D5PWW3", "url": "https://omabrowser.org/oma/group/A0A1D5PWW3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88736-1", "protein_name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "gene_name": "Hsd17b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIWTLLLPIMWLLRFFVNALTVTPYNGAEALVWLFHQKPESLNPLTKYASATSGFGTNYVTGQKMDIDEDTAEKFYEVLLELEKRVRTTVQKSDHPS", "length": 334 }, "evidence": [ { "id": "A0A1D5PWW3", "url": "https://omabrowser.org/oma/group/A0A1D5PWW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56937-1", "protein_name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "gene_name": "HSD17B7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIWTLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQKMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL", "length": 341 }, "evidence": [ { "id": "A0A1D5PWW3", "url": "https://omabrowser.org/oma/group/A0A1D5PWW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12452-1", "protein_name": "3-keto-steroid reductase ERG27", "gene_name": "ERG27", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNRKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRVEDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFTNPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRGKAYIVWISSIMSDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSEYLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSRDGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDEKLKDQIVETRTPI", "length": 347 }, "evidence": [ { "id": "A0A1D5PWW3", "url": "https://omabrowser.org/oma/group/A0A1D5PWW3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q62904-1", "protein_name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "gene_name": "Hsd17b7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKAGAVRDALLASHPSAEVSIVQMDVSNLQSVVRGAEEVKRRFQRLDYLYLNAGIMPNPQLNLKAFFCGIFSRNVIHMFSTAEGLLTQNDKITADGFQEVFETNLFGHFILIRELEPLLCHSDNPSQLIWTSSRNAKKSNFSLEDIQHAKGQEPYSSSKYATDLLNVALNRNFNQKGLYSSVTCPGVVMTNLTYGILPPFVWTLLLPVIWLLRFFAHAFTVTPYNGAEALVWLFHQKPESLNPLTKYLSGTTGLGTNYVKGQKMDVDEDTAEKFYKTLLELEKQVRITIQKSDHHS", "length": 334 }, "evidence": [ { "id": "A0A1D5PWW3", "url": "https://omabrowser.org/oma/group/A0A1D5PWW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "estrogen biosynthetic process", "id": "GO:0006703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006703", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "androgen metabolic process", "id": "GO:0008209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008209", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via lathosterol", "id": "GO:0033490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033490", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "zymosterol biosynthetic process", "id": "GO:0036197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036197", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity", "id": "GO:0000253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000253", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" }, { "name": "5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity", "id": "GO:0047024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047024", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWW3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16297", "name": "", "equation": "5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "16297", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16297" } ] }, { "id": "18409", "name": "", "equation": "4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "18409", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18409" } ] }, { "id": "24616", "name": "", "equation": "17beta-estradiol + NADP(+) = estrone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q71R50-1", "A0A8V0ZBE0-1", "A0A8V0XK46-1", "A0A8V0XL59-1", "A0A1D5PWW3-1" ], "evidence": [ { "id": "24616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24616" } ] }, { "id": "33459", "name": "", "equation": "zymosterone + NADPH + H(+) = zymosterol + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "33459", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33459" } ] }, { "id": "34787", "name": "", "equation": "a 3beta-hydroxysteroid + NADP(+) = a 3-oxosteroid + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q71R50-1", "A0A1D5PWW3-1" ], "evidence": [ { "id": "34787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34787" } ] }, { "id": "36379", "name": "", "equation": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "36379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36379" } ] }, { "id": "46832", "name": "", "equation": "4alpha-methyl-5alpha-cholest-8-en-3-one + NADPH + H(+) = 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "46832", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46832" } ] }, { "id": "46852", "name": "", "equation": "5alpha-cholest-8-en-3-one + NADPH + H(+) = 5alpha-cholest-8-en-3beta-ol + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "46852", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46852" } ] }, { "id": "R-GGA-194632", "name": "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-194691" ], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "R-GGA-194632", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194632" } ] }, { "id": "R-GGA-194689", "name": "4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "R-GGA-194689", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194689" } ] }, { "id": "R-GGA-9945784", "name": "HSD17B7 reduces 4a-methyl-5a-cholest-8-en-3-one to 4a-methyl-5a-cholest-8-en-3b-ol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-9945808" ], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "R-GGA-9945784", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9945784" } ] }, { "id": "R-GGA-9945804", "name": "HSD17B7 reduces 5a-cholest-8-en-3-one to ZYMSTNL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-9945794" ], "output_participant_list": [ "R-ALL-6807048" ], "enzyme_list": [ "A0A1D5PWW3-1" ], "evidence": [ { "id": "R-GGA-9945804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9945804" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-194691", "participant_name": "ZYMOL [endoplasmic reticulum membrane]", "crossref": [ { "id": "18252", "database": "ChEBI", "url": "" }, { "id": "ZINC000003824122", "database": "ZINC", "url": "" }, { "id": "HMDB0006271", "database": "HMDB Metabolite", "url": "" }, { "id": "C05437", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-6807048", "participant_name": "ZYMSTNL [endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000003869492", "database": "ZINC", "url": "" }, { "id": "16608", "database": "ChEBI", "url": "" }, { "id": "HMDB0006841", "database": "HMDB Metabolite", "url": "" }, { "id": "C03845", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-9945794", "participant_name": "5a-cholest-8-en-3-one [endoplasmic reticulum membrane]", "crossref": [ { "id": "87056", "database": "ChEBI", "url": "" }, { "id": "ZINC000040165516", "database": "ZINC", "url": "" }, { "id": "HMDB0062414", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-9945808", "participant_name": "4a-me-5a-cholest-8-en-3b-ol [endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000004096613", "database": "ZINC", "url": "" }, { "id": "HMDB0062394", "database": "HMDB Metabolite", "url": "" }, { "id": "87051", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PWW3", "gene_name": "HSD17B7", "activity": [ { "ec_number": "1.1.1.270", "activity": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+).", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "ec_number": "1.1.1.210", "activity": "5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+).", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "ec_number": "1.1.1.210", "activity": "", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] }, { "ec_number": "1.1.1.270", "activity": "", "evidence": [ { "id": "A0A1D5PWW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWW3" } ] } ] }, { "uniprot_ac": "A0A8V0XK46", "gene_name": "HSD17B13", "activity": [ { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A0A8V0XK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XK46" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A0A8V0XK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XK46" } ] } ] }, { "uniprot_ac": "A0A8V0XL59", "gene_name": "HSD17B11", "activity": [ { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A0A8V0XL59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL59" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A0A8V0XL59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL59" } ] } ] }, { "uniprot_ac": "A0A8V0ZBE0", "gene_name": "HSD17B12", "activity": [ { "ec_number": "1.1.1.330", "activity": "a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+).", "evidence": [ { "id": "A0A8V0ZBE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE0" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A0A8V0ZBE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE0" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A0A8V0ZBE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE0" } ] }, { "ec_number": "1.1.1.330", "activity": "", "evidence": [ { "id": "A0A8V0ZBE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE0" } ] } ] }, { "uniprot_ac": "Q71R50", "gene_name": "DHRS11", "activity": [ { "ec_number": "1.1.1.270", "activity": 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This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148815" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0", "locus": {} } ], "crossref": [ { "id": "A0A1L1RLR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RLR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041419", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11509", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11509", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100861584", "url": "https://www.ncbi.nlm.nih.gov/gene/100861584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100861584", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100861584", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKWCWLF", "url": "https://omabrowser.org/oma/group/MKWCWLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PU08", "url": "https://www.orthodb.org/?gene=A0A1D5PU08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RLR0", "url": "https://www.orthodb.org/?gene=A0A1L1RLR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PU08", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PU08-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RLR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPVPADTAAPQPPAAPSRDAAAPTGSEGTEPPAAGEERTVTAPLVGAPGPPKTAAPERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEVALGQFMKQGGIAAWNIAPLFKGLGLASMVIVFFCNSYYIMILVWGLFYLVHSLTDTLPWATCGHAWNTERCAEFFHLELCRNASANASAAVTALNVSCVDMADKRSPVIEFWENKVLRLSGDLSEPGEMNWQMILCLVTTWIIVYFCIWKGVKSTGKIVYFTALFPYVVLILLLVHGVTLPGALGGIVYYLKPDWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAVINSSTSFFAGFVVFSVLGFMASEQGVDISKVAESGPGLAFIAYPKAVTLMPLSPLWATLFFFMLLVLGLDSQFVGVEGFITGILDLFPQPGAGSLRREITAALCCLVCCLIDLSMVTQGGMYVFQLFDNYSASGITLLWQAFWECVVIAWVYGADRFMDDVARMIGYRPLPLMKWCWAVVTPLVCVGIFLFHVVNYKPLTYNKTYVYPWWGDAIGWVLALSSMLCIPCTVIYKLLRCKGSLRERWQLLTTPIWGHHHLEYLTPEAEAKLLAPEPPKEKTTLFETVI", "length": 647, "header": "tr|A0A1L1RLR0-1|A0A1L1RLR0_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A8 PE=3 SV=1 CANONICAL=A0A1L1RLR0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PU08-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PU08/entry", "sequence": { "sequence": "MDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEVALGQFMKQGGIAAWNIAPLFKGLGLASMVIVFFCNSYYIMILVWGLFYLVHSLTDTLPWATCGHAWNTERCAEFFHLELCRNASANASAAVTALNVSCVDMADKRSPVIEFWENKVLRLSGDLSEPGEMNWQMILCLVTTWIIVYFCIWKGVKSTGKIVYFTALFPYVVLILLLVHGVTLPGALGGIVYYLKPDWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAVINSSTSFFAGFVVFSVLGFMASEQGVDISKVAESGPGLAFIAYPKAVTLMPLSPLWATLFFFMLLVLGLDSQFVGVEGFITGILDLFPQPGAGSLRREITAALCCLVCCLIDLSMVTQGGMYVFQLFDNYSASGITLLWQAFWECVVIAWVYGADRFMDDVARMIGYRPLPLMKWCWAVVTPLVCVGIFLFHVVNYKPLTYNKTYVYPWWGDAIGWVLALSSMLCIPCTVIYKLLRCKGSLRERWQLLTTPIWGHHHLEYLTPEAEAKLLAPEPPKEKTTLFETVI", "length": 582, "header": "tr|A0A1D5PU08-1|A0A1L1RLR0_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A8 PE=3 SV=2 CANONICAL=A0A1L1RLR0-1" }, "locus": { "chromosome": "12", "start_pos": 11778104, "end_pos": 11774271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049737.1", "url": "https://www.ensembl.org/id/ENSGALT00010049737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029387.1", "url": "https://www.ensembl.org/id/ENSGALP00010029387.1" } ] } }, { "isoform_ac": "A0A1L1RLR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0/entry", "sequence": { "sequence": "MPPVPADTAAPQPPAAPSRDAAAPTGSEGTEPPAAGEERTVTAPLVGAPGPPKTAAPERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEVALGQFMKQGGIAAWNIAPLFKGLGLASMVIVFFCNSYYIMILVWGLFYLVHSLTDTLPWATCGHAWNTERCAEFFHLELCRNASANASAAVTALNVSCVDMADKRSPVIEFWENKVLRLSGDLSEPGEMNWQMILCLVTTWIIVYFCIWKGVKSTGKIVYFTALFPYVVLILLLVHGVTLPGALGGIVYYLKPDWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAVINSSTSFFAGFVVFSVLGFMASEQGVDISKVAESGPGLAFIAYPKAVTLMPLSPLWATLFFFMLLVLGLDSQFVGVEGFITGILDLFPQPGAGSLRREITAALCCLVCCLIDLSMVTQGGMYVFQLFDNYSASGITLLWQAFWECVVIAWVYGADRFMDDVARMIGYRPLPLMKWCWAVVTPLVCVGIFLFHVVNYKPLTYNKTYVYPWWGDAIGWVLALSSMLCIPCTVIYKLLRCKGSLRERWQLLTTPIWGHHHLEYLTPEAEAKLLAPEPPKEKTTLFETVI", "length": 647, "header": "tr|A0A1L1RLR0-1|A0A1L1RLR0_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A8 PE=3 SV=1 CANONICAL=A0A1L1RLR0-1" }, "locus": { "chromosome": "12", "start_pos": 11778104, "end_pos": 11773712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049741.1", "url": "https://www.ensembl.org/id/ENSGALT00010049741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029391.1", "url": "https://www.ensembl.org/id/ENSGALP00010029391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100861584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100861584", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7EXM3-1", "protein_name": "Transporter", "gene_name": "si:ch211-117c9.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPEEHFSNDGGSCEDESQEDAEVARPLVSETEGSNTDVAEPSVCAGLVDTGDPTAELGHSDRQTWSRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILMVFFGGIPVFFLEIALGQFMKQGGVATWNIAPLFKGLGLASMVIVFFCNTYYIMVLVWGLYFLAHSFTSSLPWATCGHEWNTINCTTNFSRVCFNQSPSHPNNSSLNISAGCLEPTGLRSSVMEFWERKVLRLSGGLDEVGDISGHMVLCLLATWIIVYFCIWKGVKSAGKVVYFTAVFPYLVLVVLFVHGVSLPGAINGIIYYLKPNWSKLSEAQVWIDAATQIFFSYAIGLGALTALGSYNRFNNNCYQDAFILALINSGTSFFAGFVVFSVLGFMAAEQDVDISNVAESGPGLAFIAYPKAVSLMPLAPLWAVLFFLMLLVLGLDSQFVGVEGFITGIMDMLPPKSFIGSLRREVVVAICCFTCFTIDLSMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVVAWVYGADRFMDDVACMIGYRPLPYMKWCWSYITPVVCMGVFLFHVVNYKRLVYNAVYVYPWWGEALGWFLALSSMLCIPLTVLYKLLHCKGSLMERWQHLTTPIWGRHHLEFLPPENEARLLAKAEENKSTLLYESVI", "length": 652 }, "evidence": [ { "id": "A0A1L1RLR0", "url": "https://omabrowser.org/oma/group/A0A1L1RLR0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid:sodium:chloride symporter activity", "id": "GO:0005332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005332", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RLR0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RLR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RLR0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 647, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RLR0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RLR0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 563, "end_pos": 565 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUB7-1", "uniprot_ac": "A0A1D5PUB7", "uniprot_id": "A0A1D5PUB7_CHICK", "mass": { "chemical_mass": 43583.0, "monoisotopic_mass": 43583.0 }, "refseq": { "ac": "XP_004934656", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934656" }, "gene_names": [ { "name": "AGPAT3", "type": "recommended", "evidence": [ { "id": "A0A1D5PUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ] }, { "name": "AGPAT3", "type": "synonym", "evidence": [ { "id": "XP_004934656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934656" } ] } ], "protein_names": [ { "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "type": "synonym", "evidence": [ { "id": "XP_004934656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934656" } ] }, { "name": "1-acylglycerol-3-phosphate O-acyltransferase 3", "type": "synonym", "evidence": [ { "id": "A0A1D5PUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934656", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934656" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AGPAT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7", "locus": { "chromosome": "1", "start_pos": 110333289, "end_pos": 110306279, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011961", "url": "https://www.ensembl.org/id/ENSGALG00010011961" } ] } } ], "crossref": [ { "id": "A0A1D5PUB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031932", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418550", "url": "https://www.ncbi.nlm.nih.gov/gene/418550", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418550", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418550", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMVMIAN", "url": "https://omabrowser.org/oma/group/RMVMIAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUB7", "url": "https://www.orthodb.org/?gene=A0A1D5PUB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004934656", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934656", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y713", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y713", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y713-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y713-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFIAFLKTQFIVHLLIGFVFVVSGLIINFIQLCTLVLWPINKQFYRRVNCRLAYSLWSQLVMLLEWWSGTECTLFSDEATVNTFGKEHVIIILNHNFEIDFLCGWTMTERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLKRLADYPEYMWFLLYCEGTRFTETKHRISMEVAESKGLPKLKYHLLPRTKGFTTAVQCLRGTVSAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPQDEKEAANWLHKLYQEKDALQEMYNQEGTFPGQQFKPPRRPWTLVNFLFWATVLLSPLFTFGFGVFASGSPLLILAFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376, "header": "tr|A0A1D5PUB7-1|A0A1D5PUB7_CHICK Isoform 1 of 1-acylglycerol-3-phosphate O-acyltransferase 3 OS=Gallus gallus OX=9031 GN=AGPAT3 PE=1 SV=1 CANONICAL=A0A1D5PUB7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7/entry", "sequence": { "sequence": "MGFIAFLKTQFIVHLLIGFVFVVSGLIINFIQLCTLVLWPINKQFYRRVNCRLAYSLWSQLVMLLEWWSGTECTLFSDEATVNTFGKEHVIIILNHNFEIDFLCGWTMTERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLKRLADYPEYMWFLLYCEGTRFTETKHRISMEVAESKGLPKLKYHLLPRTKGFTTAVQCLRGTVSAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPQDEKEAANWLHKLYQEKDALQEMYNQEGTFPGQQFKPPRRPWTLVNFLFWATVLLSPLFTFGFGVFASGSPLLILAFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376, "header": "tr|A0A1D5PUB7-1|A0A1D5PUB7_CHICK Isoform 1 of 1-acylglycerol-3-phosphate O-acyltransferase 3 OS=Gallus gallus OX=9031 GN=AGPAT3 PE=1 SV=1 CANONICAL=A0A1D5PUB7-1" }, "locus": { "chromosome": "1", "start_pos": 110330283, "end_pos": 110316046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028633.1", "url": "https://www.ensembl.org/id/ENSGALT00010028633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016449.1", "url": "https://www.ensembl.org/id/ENSGALP00010016449.1" } ] } }, { "isoform_ac": "A0A8V0Y713-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y713/entry", "sequence": { "sequence": "MGFIAFLKTQFIVHLLIGFVFVVSGLIINFIQLCTLVLWPINKQFYRRVNCRLAYSLWSQLVMLLEWWSGTECTLFSDEATVNTFGKEHVIIILNHNFEIDFLCGWTMTERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLKRLADYPEYMWFLLYCEGTRFTETKHRISMEVAESKGLPKLKYHLLPRTKGFTTAVQCLRGTAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPQDEKEAANWLHKLYQEKDALQEMYNQEGTFPGQQFKPPRRPWTLVNFLFWATVLLSPLFTFGFGVFASGSPLLILAFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 374, "header": "tr|A0A8V0Y713-1|A0A1D5PUB7_CHICK Computationally mapped isoform of 1-acylglycerol-3-phosphate O-acyltransferase 3 OS=Gallus gallus OX=9031 GN=AGPAT3 PE=1 SV=1 CANONICAL=A0A1D5PUB7-1" }, "locus": { "chromosome": "1", "start_pos": 110330283, "end_pos": 110316046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028637.1", "url": "https://www.ensembl.org/id/ENSGALT00010028637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016453.1", "url": "https://www.ensembl.org/id/ENSGALP00010016453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418550", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V648-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase 3", "gene_name": "Agpat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALWPISKNLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVNHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLANYPEYMWFLLYCEGTRFTETKHRVSMEVAASKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPADETGAAQWLHKLYQEKDALQEMYKQSGVFPGEQIKPARRPWTLLNFLCWATFLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A1D5PUB7", "url": "https://omabrowser.org/oma/group/A0A1D5PUB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E5P6-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase 3", "gene_name": "AGPAT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLLAFLKTQFVVHLLIGFVFVVSGLVINSIQLCTLVLWPVNKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDTFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIKGLKSLANYPEYMWFLLYCEGTRFTEKKHRVSMEVAASKGLPVLKYHLLPRTKGFTTAVQCLRGTVTAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEEIPLDEKEAAQWLHKLYQEKDALQEIYNQKGVFPGQQFKPTRRPWTLLNFLFWATLLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376 }, "evidence": [ { "id": "A0A1D5PUB7", "url": "https://omabrowser.org/oma/group/A0A1D5PUB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D517-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALWPISKHLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLADYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPADETSAAQWLHKLYQEKDALQEMYKQKGVFPGEQFKPARRPWTLLNFLCWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A1D5PUB7", "url": "https://omabrowser.org/oma/group/A0A1D5PUB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRZ7-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "AGPAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFKPARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376 }, "evidence": [ { "id": "A0A1D5PUB7", "url": "https://omabrowser.org/oma/group/A0A1D5PUB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PUB7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 376, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PUB7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUB7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUB7" }, { "id": "SM00563", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00563" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipid/glycerol acyltransferase", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 212, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUH8-1", "uniprot_ac": "A0A1D5PUH8", "uniprot_id": "A0A1D5PUH8_CHICK", "mass": { "chemical_mass": 32359.0, "monoisotopic_mass": 32359.0 }, "refseq": { "ac": "XP_423190", "name": "zinc finger matrin-type protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423190" }, "gene_names": [ { "name": "ZMAT3", "type": "recommended", "evidence": [ { "id": "A0A1D5PUH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ] }, { "name": "ZMAT3", "type": "synonym", "evidence": [ { "id": "XP_423190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423190" } ] } ], "protein_names": [ { "name": "Zinc finger matrin-type protein 3", "type": "recommended", "evidence": [ { "id": "A0A1D5PUH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger matrin-type protein 3", "type": "synonym", "evidence": [ { "id": "XP_423190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423190" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_423190.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423190" } ] }, { "annotation": "Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8#function" }, { "database": "UniProtKB", "id": "ARBA00054392", "url": "https://www.uniprot.org/uniprotkb/ARBA00054392#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMAT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8", "locus": { "chromosome": "9", "start_pos": 17288119, "end_pos": 17279277, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018317", "url": "https://www.ensembl.org/id/ENSGALG00010018317" } ] } } ], "crossref": [ { "id": "A0A1D5PUH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040948", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040948", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425428", "url": "https://www.ncbi.nlm.nih.gov/gene/425428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRGKNHA", "url": "https://omabrowser.org/oma/group/YRGKNHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUH8", "url": "https://www.orthodb.org/?gene=A0A1D5PUH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46786", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46786", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46786:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46786:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILLQQAGLLSHPEKPSSLPMSVATRPRATSPLSPPKSLGLGPSFYHAQDEELAKVVEQDPMLEELCKPLCCKLCNVTLNSAQQAQAHYQGKNHSKKLRNYYAANSCPAPTRMSNSVEPVPPQVVSLPAQMGSSKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQNNSFSDASELGKRRTRKEGNEYKMMQNRRNMYTVQNNTGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNAGASEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYVQ", "length": 289, "header": "tr|A0A1D5PUH8-1|A0A1D5PUH8_CHICK Isoform 1 of Zinc finger matrin-type protein 3 OS=Gallus gallus OX=9031 GN=ZMAT3 PE=4 SV=1 CANONICAL=A0A1D5PUH8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8/entry", "sequence": { "sequence": "MILLQQAGLLSHPEKPSSLPMSVATRPRATSPLSPPKSLGLGPSFYHAQDEELAKVVEQDPMLEELCKPLCCKLCNVTLNSAQQAQAHYQGKNHSKKLRNYYAANSCPAPTRMSNSVEPVPPQVVSLPAQMGSSKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQNNSFSDASELGKRRTRKEGNEYKMMQNRRNMYTVQNNTGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNAGASEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYVQ", "length": 289, "header": "tr|A0A1D5PUH8-1|A0A1D5PUH8_CHICK Isoform 1 of Zinc finger matrin-type protein 3 OS=Gallus gallus OX=9031 GN=ZMAT3 PE=4 SV=1 CANONICAL=A0A1D5PUH8-1" }, "locus": { "chromosome": "9", "start_pos": 17287982, "end_pos": 17282551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044183.1", "url": "https://www.ensembl.org/id/ENSGALT00010044183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026277.1", "url": "https://www.ensembl.org/id/ENSGALP00010026277.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 240, "start_aa": "Thr", "end_pos": 240, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr240", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:425428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425428", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BFA4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MILLQHAGLPPPKRPSSSLPMSVAARSTGTFQLPPPKAFGQEASLSLAGEEELPKGGEQDSALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNAVEPVATTAVPVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSEVGQRRTRKEGNEYKMMPNRRNMYAVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7EZ09-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "zmat3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMNVKNRDAFYSGADYCNIYSSQPVNYGDCSHYFPRITGPDPILKPPISLMCQQPPQPFQAMTPTQNLRPPPVMMPDPLPFPHCTPPIKPPPHLQLPPNPPLPPPPVISPKPPEEDAQAVAADQEATLEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHSKKLRNFYAGSQQPPPITIPEVVEPVSQQPSATTPTDSANATANQPLTKGASRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQQNATSSDLSDTQRRPRKEGYEYRLMKNRRAQFNTAMPGPYYNPRPRQRIPRDLAMCVTPSGQFYCSMCNSGASEEAEFRLHLESKQHKSRVSEQRYRSEMENLGYT", "length": 361 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I1C4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILLQQAGLPPPKRPSTSPPMSVAARSTRTLQLPPQKPFGQEASLPLAGEEELTKGEEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPTRMSTVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSDSAAEAGQRRTRKEGSEFKMVATRRNMHTVQNNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 290 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08781-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILLQQVWLPLPNRPSTSPPMSVAARSTGTLQLPPQKAFGQEASLPLAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSSVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVTTRRNMYTVQSNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 289 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54836-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILLQQVWLPLPNRPSTSPPMSVAARSTRTLQLPPQKAFGQEASLPLAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARVSSVVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVATRRNMNPVQSNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 290 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0IIC4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MILLQHAGLPPPKRPSSSPPMSVAARSTGALQLPPQKPFGQEASLPLAGEEEPPKGGEQDTALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNAVEAVAAPAVSVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSDSSEVGQRRTRKEGNEYKMMPNRRNMYAVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9HA38-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILLQHAVLPPPKQPSPSPPMSVATRSTGTLQLPPQKPFGQEASLPLAGEEELSKGGEQDCALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNVVEPAATPVVPVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSELGQRRARKEGNEFKMMPNRRNMYTVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "A0A1D5PUH8", "url": "https://omabrowser.org/oma/group/A0A1D5PUH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PUH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PUH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUH8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 240 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUJ3-1", "uniprot_ac": "A0A1D5PUJ3", "uniprot_id": "A0A1D5PUJ3_CHICK", "mass": { "chemical_mass": 106972.0, "monoisotopic_mass": 106972.0 }, "refseq": {}, "gene_names": [ { "name": "SYTL2L", "type": "recommended", "evidence": [ { "id": "A0A1D5PUJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ] } ], "protein_names": [ { "name": "Synaptotagmin-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A1D5PUJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYTL2L", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3", "locus": {} } ], "crossref": [ { "id": "A0A1D5PUJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008326", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422353", "url": "https://www.ncbi.nlm.nih.gov/gene/422353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422353", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWQEMML", "url": "https://omabrowser.org/oma/group/FWQEMML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUJ3", "url": "https://www.orthodb.org/?gene=A0A1D5PUJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTR3", "url": "https://www.orthodb.org/?gene=A0A8V0YTR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDLSFLTEEEYEKLMKVLQRDAELKKKDGDRIRRIQGSIKDEKKKKFVTGEWFSEVKAKRFQEDLEGSDLLRASIRRKKGKLENEVNEHVGRSLESKDAPGLPFHEHAAGTGEERSSTPALVTAEEHKILPKPKPRHSVLLSASHKRFSIHDVSSSESDTGASPFAAATDSLHLSRKGNGQSPPPAKLSDDAVPQPSCATGEAAEGATTAGPKSAPEEAHAPSRIPVKRKPNRSLSRSEQFANHLGPAENNLEKRELLASPRLLTTEGESSQTVKPGVNYTISSMSNKEEDIGLDREHFKNLKNFWEKGADSVMMGSMPESPGSLEADGRQFKLCRSLSVQSGHGQNSEEKPGAFTKTRTPYKRTITLSSSEEEPSYVAPVRKGSISIAPRSTYAKSKGGLVTRNSSLGESNGKPSVPEEEKAAQRSSKKSRLPVRVPSIKIESPTKEVSGSVFEPETPTEKFIVAEERKRTVSSLASRAQTLIEPALAGGDKDDEKAQRSDVGTHDNMQINGELPEEKTCQSTEQPTASAPAGGREAVQKMDSSVHSEEDGDHSPAAHALAQANSVILAKSMVNIYTTTETYSKPLLIPHQFLEAERVKELSRSSPLLLSETESDTASEISFQFSKHKKTPSIGSHSSDMASVSSVSGSVLSVYSGDFGSVDAQGTVEFALDYDEKNREFQVHVSQCKDLAVVDEKKDRTDPYVKTYLLPDKARMGKRKTSVKKRTVNPVYNEVLRYKIEKMVLLIQKLNLSVWHNDPLGRNSFLGEIELDLASWDWSNRKLNWYPLKPRSLSAVNGVDHRGVMNLSIKYVPPGSLGPKNPPSGEVHIWVKDVKDLLQLRPCGVDSFVKCYVLPDTSKKSYQKTRVVKRDTNPVFNHTIVYDGFHTEDLKDACVELTVWDHEKLTNHFLGGIRLGLGTGLSYGIPVDWMDSTQEEVAFWQDMMSATNEWIEGLLPLRSLAGRKKLK", "length": 968, "header": "tr|A0A1D5PUJ3-1|A0A1D5PUJ3_CHICK Isoform 1 of Synaptotagmin-like protein 2 OS=Gallus gallus OX=9031 GN=SYTL2L PE=1 SV=2 CANONICAL=A0A1D5PUJ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3/entry", "sequence": { "sequence": "MLDLSFLTEEEYEKLMKVLQRDAELKKKDGDRIRRIQGSIKDEKKKKFVTGEWFSEVKAKRFQEDLEGSDLLRASIRRKKGKLENEVNEHVGRSLESKDAPGLPFHEHAAGTGEERSSTPALVTAEEHKILPKPKPRHSVLLSASHKRFSIHDVSSSESDTGASPFAAATDSLHLSRKGNGQSPPPAKLSDDAVPQPSCATGEAAEGATTAGPKSAPEEAHAPSRIPVKRKPNRSLSRSEQFANHLGPAENNLEKRELLASPRLLTTEGESSQTVKPGVNYTISSMSNKEEDIGLDREHFKNLKNFWEKGADSVMMGSMPESPGSLEADGRQFKLCRSLSVQSGHGQNSEEKPGAFTKTRTPYKRTITLSSSEEEPSYVAPVRKGSISIAPRSTYAKSKGGLVTRNSSLGESNGKPSVPEEEKAAQRSSKKSRLPVRVPSIKIESPTKEVSGSVFEPETPTEKFIVAEERKRTVSSLASRAQTLIEPALAGGDKDDEKAQRSDVGTHDNMQINGELPEEKTCQSTEQPTASAPAGGREAVQKMDSSVHSEEDGDHSPAAHALAQANSVILAKSMVNIYTTTETYSKPLLIPHQFLEAERVKELSRSSPLLLSETESDTASEISFQFSKHKKTPSIGSHSSDMASVSSVSGSVLSVYSGDFGSVDAQGTVEFALDYDEKNREFQVHVSQCKDLAVVDEKKDRTDPYVKTYLLPDKARMGKRKTSVKKRTVNPVYNEVLRYKIEKMVLLIQKLNLSVWHNDPLGRNSFLGEIELDLASWDWSNRKLNWYPLKPRSLSAVNGVDHRGVMNLSIKYVPPGSLGPKNPPSGEVHIWVKDVKDLLQLRPCGVDSFVKCYVLPDTSKKSYQKTRVVKRDTNPVFNHTIVYDGFHTEDLKDACVELTVWDHEKLTNHFLGGIRLGLGTGLSYGIPVDWMDSTQEEVAFWQDMMSATNEWIEGLLPLRSLAGRKKLK", "length": 968, "header": "tr|A0A1D5PUJ3-1|A0A1D5PUJ3_CHICK Isoform 1 of Synaptotagmin-like protein 2 OS=Gallus gallus OX=9031 GN=SYTL2L PE=1 SV=2 CANONICAL=A0A1D5PUJ3-1" }, "locus": { "chromosome": "4", "start_pos": 14145644, "end_pos": 14121509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038114.1", "url": "https://www.ensembl.org/id/ENSGALT00010038114.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021992.1", "url": "https://www.ensembl.org/id/ENSGALP00010021992.1" } ] } }, { "isoform_ac": "A0A8V0YTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTR3/entry", "sequence": { "sequence": "MLDLSFLTEEEYEKLMKVLQRDAELKKKDGDRIRRIQGSIKDEKKKKFVTGEWFSEVKAKRFQEDLEGSDLLRASIRRKKGKLENEVNEHVGRSLESKDAPGLPFHEHAAGTGEERSSTPALVTAEEHKILPKPKPRHSVLLSASHKRFSIHDVSSSESDTGASPFAAATDSLHLSRKGNGQSPPPAKLSDDAVPQPSCATGEAAEGATTAGPKSAPEEAHAPSRIPVKRKPNRSLSRSEQFANHLGPAENNLEKRELLASPRLLTTEGESSQTVKPGVNYTISSMSNKEEDIGLDREHFKNLKNFWEKGADSVMMGSMPESPGSLEADGRQFKLCRSLSVQSGHGQNSEEKPGAFTKTRTPYKRTITLSSSEEEPSYVAPVRKGSISIAPRSTYAKSKGGLVTRNSSLGESNGKPSVPEEEKAAQRSSKKSRLPVRVPSIKIESPTKEVSGSVFEPETPTEKFIVAEERKRTVSSLASRAQTLIEPALAGGDKDDEKAQRSDVGTHDNMQINGELPEEKTCQSTEQPTASAPAGGREAVQKMDSSVHSEEDGDHSPAAHALAQANSVILAKSMVNIYTTTETYSKPLLIPHQFLEAERVKELSRSSPLLLSEVSGSVLSVYSGDFGSVDAQGTVEFALDYDEKNREFQVHVSQCKDLAVVDEKKDRTDPYVKTYLLPDKARMGKRKTSVKKRTVNPVYNEVLRYKIEKMVLLIQKLNLSVWHNDPLGRNSFLGEIELDLASWDWSNRKLNWYPLKPRSLSAVNGVDHRGVMNLSIKYVPPGSLGPKNPPSGEVHIWVKDVKDLLQLRPCGVDSFVKCYVLPDTSKKSYQKTRVVKRDTNPVFNHTIVYDGFHTEDLKDACVELTVWDHEKLTNHFLGGIRLGLGTGLSYGIPVDWMDSTQEEVAFWQDMMSATNEWIEGLLPLRSLAGRKKLK", "length": 934, "header": "tr|A0A8V0YTR3-1|A0A1D5PUJ3_CHICK Computationally mapped isoform of Synaptotagmin-like protein 2 OS=Gallus gallus OX=9031 GN=SYTL2L PE=1 SV=1 CANONICAL=A0A1D5PUJ3-1" }, "locus": { "chromosome": "4", "start_pos": 14145644, "end_pos": 14121509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038115.1", "url": "https://www.ensembl.org/id/ENSGALT00010038115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021993.1", "url": "https://www.ensembl.org/id/ENSGALP00010021993.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422353", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUJ3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PUJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 968, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PUJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUJ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 878, "end_pos": 880 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUM3-1", "uniprot_ac": "A0A1D5PUM3", "uniprot_id": "A0A1D5PUM3_CHICK", "mass": { "chemical_mass": 16403.0, "monoisotopic_mass": 16403.0 }, "refseq": { "ac": "XP_015139757", "name": "protein phosphatase 1 regulatory subunit 14C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139757" }, "gene_names": [ { "name": "PPP1R14C", "type": "recommended", "evidence": [ { "id": "A0A1D5PUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3" } ] }, { "name": "PPP1R14C", "type": "synonym", "evidence": [ { "id": "XP_015139757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139757" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory inhibitor subunit 14C", "type": "synonym", "evidence": [ { "id": "A0A1D5PUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 14C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139757" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139757" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R14C", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3", "locus": { "chromosome": "3", "start_pos": 48058028, "end_pos": 48006384, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005553", "url": "https://www.ensembl.org/id/ENSGALG00010005553" } ] } } ], "crossref": [ { "id": "A0A1D5PUM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041575", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041575", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421630", "url": "https://www.ncbi.nlm.nih.gov/gene/421630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421630", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PARVFFQ", "url": "https://omabrowser.org/oma/group/PARVFFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUM3", "url": "https://www.orthodb.org/?gene=A0A1D5PUM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XI66", "url": "https://www.orthodb.org/?gene=A0A8V0XI66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPN8", "url": "https://www.orthodb.org/?gene=A0A8V0XPN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16188:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16188:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05361", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05361", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVATGGSEAAAAAGGGGGGGRVFFQSPRGGGSGREDAVSAAAVQVQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCQEEEMPDVEIDIDDLLDAANEEERALKLQETLVDCYKPTEEFIKELLTRIRGMRKLSPPQKKSI", "length": 149, "header": "tr|A0A1D5PUM3-1|A0A1D5PUM3_CHICK Isoform 1 of Protein phosphatase 1 regulatory inhibitor subunit 14C OS=Gallus gallus OX=9031 GN=PPP1R14C PE=3 SV=1 CANONICAL=A0A1D5PUM3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3/entry", "sequence": { "sequence": "MSVATGGSEAAAAAGGGGGGGRVFFQSPRGGGSGREDAVSAAAVQVQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCQEEEMPDVEIDIDDLLDAANEEERALKLQETLVDCYKPTEEFIKELLTRIRGMRKLSPPQKKSI", "length": 149, "header": "tr|A0A1D5PUM3-1|A0A1D5PUM3_CHICK Isoform 1 of Protein phosphatase 1 regulatory inhibitor subunit 14C OS=Gallus gallus OX=9031 GN=PPP1R14C PE=3 SV=1 CANONICAL=A0A1D5PUM3-1" }, "locus": { "chromosome": "3", "start_pos": 48056777, "end_pos": 48006520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013290.1", "url": "https://www.ensembl.org/id/ENSGALT00010013290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007852.1", "url": "https://www.ensembl.org/id/ENSGALP00010007852.1" } ] } }, { "isoform_ac": "A0A8V0XI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI66/entry", "sequence": { "sequence": "MSVATGGSEAAAAAGGGGGGGRVFFQSPRGGGSGREDAVSAAAVQVQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCQEEEMPDVEIDIDDLLDAANEEERALKLQETLVDCYKPTEYRYALRASGCTPQRNNLNLSKSC", "length": 148, "header": "tr|A0A8V0XI66-1|A0A1D5PUM3_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory inhibitor subunit 14C OS=Gallus gallus OX=9031 GN=PPP1R14C PE=3 SV=1 CANONICAL=A0A1D5PUM3-1" }, "locus": { "chromosome": "3", "start_pos": 48056724, "end_pos": 48006520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013285.1", "url": "https://www.ensembl.org/id/ENSGALT00010013285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007847.1", "url": "https://www.ensembl.org/id/ENSGALP00010007847.1" } ] } }, { "isoform_ac": "A0A8V0XPN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPN8/entry", "sequence": { "sequence": "MSVATGGSEAAAAAGGGGGGGRVFFQSPRGGGSGREDAVSAAAVQVQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCQEEEMPDVEIDIDDLLDAANEEERALKLQEFIKELLTRIRGMRKLSPPQKKSI", "length": 138, "header": "tr|A0A8V0XPN8-1|A0A1D5PUM3_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory inhibitor subunit 14C OS=Gallus gallus OX=9031 GN=PPP1R14C PE=3 SV=1 CANONICAL=A0A1D5PUM3-1" }, "locus": { "chromosome": "3", "start_pos": 48056777, "end_pos": 48006520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013287.1", "url": "https://www.ensembl.org/id/ENSGALT00010013287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007849.1", "url": "https://www.ensembl.org/id/ENSGALP00010007849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421630", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RL03-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14", "gene_name": "PPP1R14C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVATGSNEAAGGAGGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAVATGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERALKLREALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKTV", "length": 165 }, "evidence": [ { "id": "A0A1D5PUM3", "url": "https://omabrowser.org/oma/group/A0A1D5PUM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R4S0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVVTGGGEAAGGGGGGGARVFFQSPRGGTGGSPGSSSSSGSSREDSAPVTTVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDANSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A1D5PUM3", "url": "https://omabrowser.org/oma/group/A0A1D5PUM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAE6-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "PPP1R14C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVATGSSETAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKSV", "length": 165 }, "evidence": [ { "id": "A0A1D5PUM3", "url": "https://omabrowser.org/oma/group/A0A1D5PUM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PUM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PUM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUM3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PUT3-1", "uniprot_ac": "A0A1D5PUT3", "uniprot_id": "A0A1D5PUT3_CHICK", "mass": { "chemical_mass": 37898.0, "monoisotopic_mass": 37898.0 }, "refseq": { "ac": "NP_001026192", "name": "DGAT1/2-independent enzyme synthesizing storage lipids", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" }, "gene_names": [ { "name": "TMEM68", "type": "recommended", "evidence": [ { "id": "A0A1D5PUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3" } ] }, { "name": "DIESL", "type": "synonym", "evidence": [ { "id": "NP_001026192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] }, { "name": "MGAT/DGAT", "type": "synonym", "evidence": [ { "id": "NP_001026192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] }, { "name": "TMEM68", "type": "synonym", "evidence": [ { "id": "NP_001026192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] } ], "protein_names": [ { "name": "DGAT1/2-independent enzyme synthesizing storage lipids", "type": "synonym", "evidence": [ { "id": "NP_001026192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] }, { "name": "Transmembrane protein 68", "type": "synonym", "evidence": [ { "id": "A0A1D5PUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3/entry#names_and_taxonomy" } ] }, { "name": "monoacylglycerol/Diacylglycerol O-acyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001026192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720496.1, SRR13267649.194468.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000043.1. On Sep 23, 2021 this sequence version replaced NP_001026192.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM68", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3", "locus": { "chromosome": "2", "start_pos": 110708526, "end_pos": 110724663, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006084", "url": "https://www.ensembl.org/id/ENSGALG00010006084" } ] } } ], "crossref": [ { "id": "A0A1D5PUT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031835", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031835", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421124", "url": "https://www.ncbi.nlm.nih.gov/gene/421124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYWNGAR", "url": "https://omabrowser.org/oma/group/SYWNGAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUT3", "url": "https://www.orthodb.org/?gene=A0A1D5PUT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XK78", "url": "https://www.orthodb.org/?gene=A0A8V0XK78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XK78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XK78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XK78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XK78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWVLFPLAIVFILPVAIFFFCFNTSLLLLHIYKRRKNGFNEGHSGDVWYGAKEMLANLWDGHGRVWHGYELHGDENIPEGPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED", "length": 332, "header": "tr|A0A1D5PUT3-1|A0A1D5PUT3_CHICK Isoform 1 of Transmembrane protein 68 OS=Gallus gallus OX=9031 GN=TMEM68 PE=4 SV=1 CANONICAL=A0A1D5PUT3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3/entry", "sequence": { "sequence": "MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWVLFPLAIVFILPVAIFFFCFNTSLLLLHIYKRRKNGFNEGHSGDVWYGAKEMLANLWDGHGRVWHGYELHGDENIPEGPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED", "length": 332, "header": "tr|A0A1D5PUT3-1|A0A1D5PUT3_CHICK Isoform 1 of Transmembrane protein 68 OS=Gallus gallus OX=9031 GN=TMEM68 PE=4 SV=1 CANONICAL=A0A1D5PUT3-1" }, "locus": { "chromosome": "2", "start_pos": 110724652, "end_pos": 110710540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014554.1", "url": "https://www.ensembl.org/id/ENSGALT00010014554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008571.1", "url": "https://www.ensembl.org/id/ENSGALP00010008571.1" } ] } }, { "isoform_ac": "A0A8V0XK78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XK78/entry", "sequence": { "sequence": "MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWRRKNGFNEGHSGDVWYGAKEMLANLWDGHGRVWHGYELHGDENIPEGPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED", "length": 301, "header": "tr|A0A8V0XK78-1|A0A1D5PUT3_CHICK Computationally mapped isoform of Transmembrane protein 68 OS=Gallus gallus OX=9031 GN=TMEM68 PE=4 SV=1 CANONICAL=A0A1D5PUT3-1" }, "locus": { "chromosome": "2", "start_pos": 110724652, "end_pos": 110710540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014556.1", "url": "https://www.ensembl.org/id/ENSGALT00010014556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008573.1", "url": "https://www.ensembl.org/id/ENSGALP00010008573.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IAZ3-1", "protein_name": "Transmembrane protein 68 isoform X1", "gene_name": "Tmem68", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLDNNQTCTVGQDCVPYMTCVVHMLEEWLGVEQLEDYLNFANYLLWVFTPLLLLILPYFTIFLLYITIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRACRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPLYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKNALQALIDKHQRIPGNIRSALLDRFHRGQQAN", "length": 329 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1WF85-1", "protein_name": "Transmembrane protein 68", "gene_name": "TMEM68", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIGKNQTCGTGQDSMPYMTCLVHILEGWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLREAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFHKKQKIN", "length": 330 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZF19-1", "protein_name": "Transmembrane protein 68", "gene_name": "Tmem68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MINNNQTCAAGQDSVPYVTCMLHVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPEVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAN", "length": 329 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VCR6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTNKNQSFGVGQDSMSSMTCLIHVLEAWFGVEHLEDYWNFANYLLWVFTPLLLLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCAIHGPREKCVEILQSGHLLAISPGGVREALMSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFRNKQKINQKTL", "length": 334 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96MH6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEDGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPQITAEELAEKTKNAVQALIDKHQRIPGNIMSALLERFH", "length": 324 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D850-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "Tmem68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDNNQTCAAGQDSVPYVTCMIYVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGAALIIFYHGAIPIDFYYFMAKIFIQKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPKVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAH", "length": 329 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZ05-1", "protein_name": "Phospholipid/glycerol acyltransferase domain-containing protein", "gene_name": "CG15197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEFLENLYKTLHSLLSSYIDLDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMRAVQGDRNFWRVGRKIVAAIWDAHARIYHGYEVIGLENVPQEGPALIVYYHGAIPIDMYYLNSRMLLQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYYELLWRNRVGFAKVAIEAKAPIIPCFTQNLREGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFPVKFRTYLGKPIPYDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFRRRVRRKEE", "length": 323 }, "evidence": [ { "id": "A0A1D5PUT3", "url": "https://omabrowser.org/oma/group/A0A1D5PUT3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PUT3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PUT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 332, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PUT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PUT3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUT3" }, { "id": "SM00563", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00563" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipid/glycerol acyltransferase", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 241, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PVL1-1", "uniprot_ac": "A0A1D5PVL1", "uniprot_id": "A0A1D5PVL1_CHICK", "mass": { "chemical_mass": 53434.0, "monoisotopic_mass": 53434.0 }, "refseq": { "ac": "XP_418315", "name": "solute carrier family 7 member 13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418315" }, "gene_names": [ { "name": "SLC7A13", "type": "recommended", "evidence": [ { "id": "A0A1D5PVL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1" } ] }, { "name": "SLC7A13", "type": "synonym", "evidence": [ { "id": "XP_418315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418315" } ] } ], "protein_names": [ { "name": "Solute carrier family 7 member 13", "type": "synonym", "evidence": [ { "id": "A0A1D5PVL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 7 member 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418315" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418315.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418315" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC7A13", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1", "locus": {} } ], "crossref": [ { "id": "A0A1D5PVL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041612", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420204", "url": "https://www.ncbi.nlm.nih.gov/gene/420204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GEACYVE", "url": "https://omabrowser.org/oma/group/GEACYVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVL1", "url": "https://www.orthodb.org/?gene=A0A1D5PVL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785:SF348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785:SF348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PVL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGKSNDPKDVKRKEKTKIQLKRRIGCFDGVSFIIGSIVGAGIFVSPTGVLKHSLLNVGVALTIWTASGLVSLMGSLCYAELGTALPFSGGEYSHIKRGLGSLPAFVFIWTSTFTKPASNAARALLFAEYATQPFYGICPAPEVLKKCLALAVLWSLGILNGRSVKVAAWVQTVFTLLKMMALSVIAIGGIVLLVGGRKENLTRFEDMFGSEMPNASQIAEAFFQGLYAYGGWWSLNYMAEEMKNPSRNIPLTVMTAVPAVIVFYLLVNISYLTVLTPKEIVSSVAVAVTWADRVIPSVAWIIPVSVAVSIFGALNSSMFTLGRLSYAGSQSGHLPVLISMLNVHTCTPAPAMIFSTTIASIFIIPSDLIMLTNYFGFSAWLMIGLTCASLIVLRYQEPNLHRPYKVFLPVPFVMVAMSFFLVLAPIVWSPNMQYFYAFLFMLGSLIVYIPFVHFKLHFAFFDKITCYLQLLLEVSPADGSDESKCE", "length": 488, "header": "tr|A0A1D5PVL1-1|A0A1D5PVL1_CHICK Isoform 1 of Solute carrier family 7 member 13 OS=Gallus gallus OX=9031 GN=SLC7A13 PE=3 SV=1 CANONICAL=A0A1D5PVL1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1/entry", "sequence": { "sequence": "MGRGKSNDPKDVKRKEKTKIQLKRRIGCFDGVSFIIGSIVGAGIFVSPTGVLKHSLLNVGVALTIWTASGLVSLMGSLCYAELGTALPFSGGEYSHIKRGLGSLPAFVFIWTSTFTKPASNAARALLFAEYATQPFYGICPAPEVLKKCLALAVLWSLGILNGRSVKVAAWVQTVFTLLKMMALSVIAIGGIVLLVGGRKENLTRFEDMFGSEMPNASQIAEAFFQGLYAYGGWWSLNYMAEEMKNPSRNIPLTVMTAVPAVIVFYLLVNISYLTVLTPKEIVSSVAVAVTWADRVIPSVAWIIPVSVAVSIFGALNSSMFTLGRLSYAGSQSGHLPVLISMLNVHTCTPAPAMIFSTTIASIFIIPSDLIMLTNYFGFSAWLMIGLTCASLIVLRYQEPNLHRPYKVFLPVPFVMVAMSFFLVLAPIVWSPNMQYFYAFLFMLGSLIVYIPFVHFKLHFAFFDKITCYLQLLLEVSPADGSDESKCE", "length": 488, "header": "tr|A0A1D5PVL1-1|A0A1D5PVL1_CHICK Isoform 1 of Solute carrier family 7 member 13 OS=Gallus gallus OX=9031 GN=SLC7A13 PE=3 SV=1 CANONICAL=A0A1D5PVL1-1" }, "locus": { "chromosome": "2", "start_pos": 122264755, "end_pos": 122259123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031705.1", "url": "https://www.ensembl.org/id/ENSGALT00010031705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018553.1", "url": "https://www.ensembl.org/id/ENSGALP00010018553.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PVL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 488, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PVL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVL1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 291 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PVS3-1", "uniprot_ac": "A0A1D5PVS3", "uniprot_id": "A0A1D5PVS3_CHICK", "mass": { "chemical_mass": 7896.0, "monoisotopic_mass": 7896.0 }, "refseq": { "ac": "NP_001289063", "name": "mitochondrial import receptor subunit TOM6 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063" }, "gene_names": [ { "name": "TOMM6", "type": "recommended", "evidence": [ { "id": "A0A1D5PVS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3" } ] }, { "name": "TOMM6", "type": "synonym", "evidence": [ { "id": "NP_001289063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063" } ] } ], "protein_names": [ { "name": "Translocase of outer mitochondrial membrane 6", "type": "synonym", "evidence": [ { "id": "A0A1D5PVS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import receptor subunit TOM6 homolog", "type": "synonym", "evidence": [ { "id": "NP_001289063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063" } ] }, { "name": "translocase of outer mitochondrial membrane 6 homolog", "type": "synonym", "evidence": [ { "id": "NP_001289063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN230088.1, AI981566.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000356.1. On Oct 2, 2014 this sequence version replaced XP_429722.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001289063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOMM6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3", "locus": { "chromosome": "26", "start_pos": 5028049, "end_pos": 5026438, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026438", "url": "https://www.ensembl.org/id/ENSGALG00010026438" } ] } } ], "crossref": [ { "id": "A0A1D5PVS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043002", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419924", "url": "https://www.ncbi.nlm.nih.gov/gene/419924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419924", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419924", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWANETL", "url": "https://omabrowser.org/oma/group/GWANETL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVS3", "url": "https://www.orthodb.org/?gene=A0A1D5PVS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15527", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15527", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15527:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15527:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001289063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGSAQAGGSVVSSPPPPPPPPQGLGGWLRAAYRFATDRNDFRRNLLVNVGLFAAGVWVARNLADIDLMAPQPVA", "length": 76, "header": "tr|A0A1D5PVS3-1|A0A1D5PVS3_CHICK Isoform 1 of Translocase of outer mitochondrial membrane 6 OS=Gallus gallus OX=9031 GN=TOMM6 PE=4 SV=1 CANONICAL=A0A1D5PVS3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3/entry", "sequence": { "sequence": "MAAGSAQAGGSVVSSPPPPPPPPQGLGGWLRAAYRFATDRNDFRRNLLVNVGLFAAGVWVARNLADIDLMAPQPVA", "length": 76, "header": "tr|A0A1D5PVS3-1|A0A1D5PVS3_CHICK Isoform 1 of Translocase of outer mitochondrial membrane 6 OS=Gallus gallus OX=9031 GN=TOMM6 PE=4 SV=1 CANONICAL=A0A1D5PVS3-1" }, "locus": { "chromosome": "26", "start_pos": 5026775, "end_pos": 5026468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064291.1", "url": "https://www.ensembl.org/id/ENSGALT00010064291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039492.1", "url": "https://www.ensembl.org/id/ENSGALP00010039492.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419924", "resource": "KEGG Pathway" }, { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PVS3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PVS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 76, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PVS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PVS3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002395", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002395", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PW43", "url": "https://www.orthodb.org/?gene=A0A1D5PW43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10957", "url": 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"METLSHHLDYLELCGDDPKAEEDIIASLNGILQALTEDKQRTFSLIKESGILLTLAKILKSNPRCAVKAAQVLSEIAKNDEMKKPCIEADLVLTLIPFLESTDQEMLLHAGRAIGRICYDNRDLQEELVKVGVIPSLVRILTDHAESEPLVHVDLLALCNLADLDTAKEALSKTKVAEQLVKQLRRAESHERLEIIFEVLQTLAENDALKVQLVEAGVQEVLSDILLRLQGSSQAEDTCIVKATSDLIVSLLLGDGNCVRMVQVGVIHQLLDLLEKHVESEDISVQHAALSALRNLAIPVVNKVQMLEEGVAERIQALLRSEMPPVQFKLLGTLRMLADGQADAAEILGQDPTLLNRLVQWCDVSDDSDVSGEANRLLASILRHNRSQEVVKAVQEAQGVKHLVSMTLSEHTAMQNEALNALAIASAIDLETLEESFKETQLVQSLHKLLQDNNTSAEVKYNSMSLLCSLLNSGHLRQEIEDSKIEETLEQLCSHNNADVVKEALTTLQILKRESPY", "length": 517, "header": "tr|A0A1D5PW43-1|A0A1D5PW43_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=RAP1GDS1L PE=4 SV=2 CANONICAL=A0A1D5PW43-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PW43-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW43/entry", "sequence": { "sequence": "METLSHHLDYLELCGDDPKAEEDIIASLNGILQALTEDKQRTFSLIKESGILLTLAKILKSNPRCAVKAAQVLSEIAKNDEMKKPCIEADLVLTLIPFLESTDQEMLLHAGRAIGRICYDNRDLQEELVKVGVIPSLVRILTDHAESEPLVHVDLLALCNLADLDTAKEALSKTKVAEQLVKQLRRAESHERLEIIFEVLQTLAENDALKVQLVEAGVQEVLSDILLRLQGSSQAEDTCIVKATSDLIVSLLLGDGNCVRMVQVGVIHQLLDLLEKHVESEDISVQHAALSALRNLAIPVVNKVQMLEEGVAERIQALLRSEMPPVQFKLLGTLRMLADGQADAAEILGQDPTLLNRLVQWCDVSDDSDVSGEANRLLASILRHNRSQEVVKAVQEAQGVKHLVSMTLSEHTAMQNEALNALAIASAIDLETLEESFKETQLVQSLHKLLQDNNTSAEVKYNSMSLLCSLLNSGHLRQEIEDSKIEETLEQLCSHNNADVVKEALTTLQILKRESPY", "length": 517, "header": "tr|A0A1D5PW43-1|A0A1D5PW43_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=RAP1GDS1L PE=4 SV=2 CANONICAL=A0A1D5PW43-1" }, "locus": { "chromosome": "6", "start_pos": 5016363, "end_pos": 4985467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026222.1", "url": "https://www.ensembl.org/id/ENSGALT00010026222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014846.1", "url": 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"name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PW43", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PW43-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 517, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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Computationally mapped isoform of Ninjurin 2 OS=Gallus gallus OX=9031 GN=NINJ2 PE=3 SV=1 CANONICAL=A0A1D5PWI1-1" }, "locus": { "chromosome": "1", "start_pos": 60422685, "end_pos": 60421563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029440.1", "url": "https://www.ensembl.org/id/ENSGALT00010029440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017103.1", "url": "https://www.ensembl.org/id/ENSGALP00010017103.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418151", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418151", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWI1", "url": 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"A0A1D5PWI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWI1" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWI1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PWI1-F1", "pdb_chain": "global", "start_pos": 1, 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The reference sequence was derived from JAENSK010000317.1. 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This record is derived from a genomic sequence (NC_052585.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PWP3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHARHRKRKRLRSSGGSGRCPGRRSAVVGMWWLLLLLAGLGRALPEGVVTETGAGSSAPISGEAVRYRTAEMADAMLGSGPPGQPPVVLSAVPGEAKEGRAAAACEAAAGGEECGAGSGPAAPPAPPGEAVVLETVLPAGEEPNGTAESVKAPKVSCEERNVTGISNFTLQILNVSQDLMEFLNPNSSDCTLVLFYTPWCRFSVSLAPHFNSLPRAFPTLRFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKDFIFNQTGIEANNDVTVTEEDWKGPLPSVLTKGVDWLLVFSVLFLASFIMYATIRTESIRWLIPGQEHEHQE", "length": 340, "header": "tr|A0A1D5PWP3-1|A0A1D5PWP3_CHICK Isoform 1 of Thioredoxin domain containing 15 OS=Gallus gallus OX=9031 GN=TXNDC15 PE=4 SV=3 CANONICAL=A0A1D5PWP3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWP3/entry", "sequence": { "sequence": 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PWT4-1", "uniprot_ac": "A0A1D5PWT4", "uniprot_id": "A0A1D5PWT4_CHICK", "mass": { "chemical_mass": 16259.0, "monoisotopic_mass": 16259.0 }, "refseq": { "ac": "NP_001383294", "name": "thioredoxin, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383294" }, "gene_names": [ { "name": "TXN2", "type": "recommended", "evidence": [ { "id": "A0A1D5PWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" } ] }, { "name": "TXN2", "type": "synonym", "evidence": [ { "id": "NP_001383294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383294" } ] } ], "protein_names": [ { "name": "Thioredoxin, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A1D5PWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4/entry#names_and_taxonomy" } ] }, { "name": "Thioredoxin-2", "type": "synonym", "evidence": [ { "id": "A0A1D5PWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4/entry#names_and_taxonomy" } ] }, { "name": "thioredoxin, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001383294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383294" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01110485.1, HAEK01000118.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Oct 17, 2021 this sequence version replaced XP_015141435.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383294" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TXN2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4", "locus": { "chromosome": "1", "start_pos": 51777147, "end_pos": 51769719, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014945", "url": "https://www.ensembl.org/id/ENSGALG00010014945" } ] } } ], "crossref": [ { "id": "A0A1D5PWT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PWT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012532", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012532", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426978", "url": "https://www.ncbi.nlm.nih.gov/gene/426978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VLVIMQN", "url": "https://omabrowser.org/oma/group/VLVIMQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWT4", "url": "https://www.orthodb.org/?gene=A0A1D5PWT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43601:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43601:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1614558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383294", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PWT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQRLALRRLLALGRRPLPLGPRPLASQGLPGRAFGSSAIRGSAFNVQDGGDFQERVVNSPKPVVVDFHAQWCGPCKILGPRLEKMVAKQDGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIGA", "length": 150, "header": "tr|A0A1D5PWT4-1|A0A1D5PWT4_CHICK Isoform 1 of Thioredoxin, mitochondrial OS=Gallus gallus OX=9031 GN=TXN2 PE=1 SV=1 CANONICAL=A0A1D5PWT4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4/entry", "sequence": { "sequence": "MAQRLALRRLLALGRRPLPLGPRPLASQGLPGRAFGSSAIRGSAFNVQDGGDFQERVVNSPKPVVVDFHAQWCGPCKILGPRLEKMVAKQDGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIGA", "length": 150, "header": "tr|A0A1D5PWT4-1|A0A1D5PWT4_CHICK Isoform 1 of Thioredoxin, mitochondrial OS=Gallus gallus OX=9031 GN=TXN2 PE=1 SV=1 CANONICAL=A0A1D5PWT4-1" }, "locus": { "chromosome": "1", "start_pos": 51776564, "end_pos": 51769723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035940.1", "url": "https://www.ensembl.org/id/ENSGALT00010035940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020859.1", "url": "https://www.ensembl.org/id/ENSGALP00010020859.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1614558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614558", "resource": "Reactome", "description": "Degradation of cysteine and homocysteine" }, { "id": "R-GGA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" } ], "orthologs": [ { "uniprot_canonical_ac": "P97493-1", "protein_name": "Thioredoxin, mitochondrial", "gene_name": "Txn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQRLLLGRFLTSVISRKPPQGVWASLTSKTLQTPQYNAGGLTVMPSPARTVHTTRVCLTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG", "length": 166 }, "evidence": [ { "id": "A0A1D5PWT4", "url": "https://omabrowser.org/oma/group/A0A1D5PWT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P97615-1", "protein_name": "Thioredoxin, mitochondrial", "gene_name": "Txn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQRLLLRRFLTSVISRKPPQGVWASLTSTSLQTPPYNAGGLTGTPSPARTFHTTRVCSTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG", "length": 166 }, "evidence": [ { "id": "A0A1D5PWT4", "url": "https://omabrowser.org/oma/group/A0A1D5PWT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q95108-1", "protein_name": "Thioredoxin, mitochondrial", "gene_name": "TXN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQRLLLRRFLTSIISGKPSQSRWAPVASRALQTPQYSPGYLTVTPSQARSIYTTRVCSTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKVVAKQHGKVVMAKVDIDDHTDLALEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG", "length": 166 }, "evidence": [ { "id": "A0A1D5PWT4", "url": "https://omabrowser.org/oma/group/A0A1D5PWT4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99757-1", "protein_name": "Thioredoxin, mitochondrial", "gene_name": "TXN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG", "length": 166 }, "evidence": [ { "id": "A0A1D5PWT4", "url": "https://omabrowser.org/oma/group/A0A1D5PWT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWT4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PWT4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 150, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PWT4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PWT4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWT4" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 149, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PXC2-1", "uniprot_ac": "A0A1D5PXC2", "uniprot_id": "A0A1D5PXC2_CHICK", "mass": { "chemical_mass": 61308.0, "monoisotopic_mass": 61308.0 }, "refseq": { "ac": "XP_414814", "name": "dynein regulatory complex subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414814" }, "gene_names": [ { "name": "DRC3", "type": "recommended", "evidence": [ { "id": "A0A1D5PXC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2" } ] }, { "name": "DRC3", "type": "synonym", "evidence": [ { "id": "XP_414814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414814" } ] } ], "protein_names": [ { "name": "Dynein regulatory complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A1D5PXC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2/entry#names_and_taxonomy" } ] }, { "name": "dynein regulatory complex subunit 3", "type": "synonym", "evidence": [ { "id": "XP_414814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414814" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414814" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DRC3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2", "locus": { "chromosome": "14", "start_pos": 4993874, "end_pos": 4978609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017570", "url": "https://www.ensembl.org/id/ENSGALG00010017570" } ] } } ], "crossref": [ { "id": "A0A1D5PXC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004916", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416510", "url": "https://www.ncbi.nlm.nih.gov/gene/416510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416510", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFMEMMT", "url": "https://omabrowser.org/oma/group/SFMEMMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXC2", "url": "https://www.orthodb.org/?gene=A0A1D5PXC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1L6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z229", "url": "https://www.orthodb.org/?gene=A0A8V0Z229", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PXC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z229", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z229", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z229-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z229-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSDNSFEPNVIDDEMLQKAVEEQWPEDIRKLAKAEGINFKDVMELQLSFRNILQIDNLWQFENLTKLQLDNNIIEKIEALESLVHLVWLDLSFNNIEVIEGLDTLVKLQDLSLYNNRISKIEHMDTLQELQIFSIGKNNLTTLENVVYLRKFKNLHTLNLTGNPFCNEEQYMLFVVAHLPGLVYLDFKLVSDTTREVAISNYHYLTDLLEHEEAQALAQLEEKQAQQKELEYHKTAFVEYLNGSFLFDSLYAEDTEAAKLAYLPGVDDLLQAYRKDFVSVCENLFNYCLKEHEKREAEVSDFYEGLREVLTANQEEGRRIILDFENQNRTRLDEIHHASSHDTAESMRAEYNEDILQLSETLMTLEMQMVDQLEELIKEFERNIAVITSTFIENVKGMMTQCRDLENRHHEKLLEISISALEKSLKNELDEELPDDVREFLVDKNTIVNMVNKSHNIHLLKISMRECDILLNMYHWEASVKEKALQNEIDRNRNRIKEIFQYIDDLQEQLDNTQIPDPTE", "length": 522, "header": "tr|A0A1D5PXC2-1|A0A1D5PXC2_CHICK Isoform 1 of Dynein regulatory complex subunit 3 OS=Gallus gallus OX=9031 GN=DRC3 PE=3 SV=3 CANONICAL=A0A1D5PXC2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2/entry", "sequence": { "sequence": "MSQSDNSFEPNVIDDEMLQKAVEEQWPEDIRKLAKAEGINFKDVMELQLSFRNILQIDNLWQFENLTKLQLDNNIIEKIEALESLVHLVWLDLSFNNIEVIEGLDTLVKLQDLSLYNNRISKIEHMDTLQELQIFSIGKNNLTTLENVVYLRKFKNLHTLNLTGNPFCNEEQYMLFVVAHLPGLVYLDFKLVSDTTREVAISNYHYLTDLLEHEEAQALAQLEEKQAQQKELEYHKTAFVEYLNGSFLFDSLYAEDTEAAKLAYLPGVDDLLQAYRKDFVSVCENLFNYCLKEHEKREAEVSDFYEGLREVLTANQEEGRRIILDFENQNRTRLDEIHHASSHDTAESMRAEYNEDILQLSETLMTLEMQMVDQLEELIKEFERNIAVITSTFIENVKGMMTQCRDLENRHHEKLLEISISALEKSLKNELDEELPDDVREFLVDKNTIVNMVNKSHNIHLLKISMRECDILLNMYHWEASVKEKALQNEIDRNRNRIKEIFQYIDDLQEQLDNTQIPDPTE", "length": 522, "header": "tr|A0A1D5PXC2-1|A0A1D5PXC2_CHICK Isoform 1 of Dynein regulatory complex subunit 3 OS=Gallus gallus OX=9031 GN=DRC3 PE=3 SV=3 CANONICAL=A0A1D5PXC2-1" }, "locus": { "chromosome": "14", "start_pos": 4993697, "end_pos": 4979435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042468.1", "url": "https://www.ensembl.org/id/ENSGALT00010042468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024958.1", "url": "https://www.ensembl.org/id/ENSGALP00010024958.1" } ] } }, { "isoform_ac": "A0A8V0Z1L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L6/entry", "sequence": { "sequence": "MSQSDNSFEPNVIDDEMLQKAVEEQWPEDIRKLAKAEGINFKDVMELQLSFRNILQIDNLWQFENLTKLQLDNNIIEKIEALESLVHLVWLDLSFNNIEVIEGLDTLVKLQDLSLYNNRISKIEHMDTLQELQIFSIGKNNLTTLENVVYLRKFKNLHTLNLTGNPFCNEEQYMLFVVAHLPGLVYLDFKLVSDTTREVAISNYHYLTDLLEHEEAQALAQLEEKQAQQKELEYHKIVTCSAHQYSSTGKELLGERHPKDWQQFVCRGYRSCQTGLPPRSG", "length": 281, "header": "tr|A0A8V0Z1L6-1|A0A1D5PXC2_CHICK Computationally mapped isoform of Dynein regulatory complex subunit 3 OS=Gallus gallus OX=9031 GN=DRC3 PE=3 SV=1 CANONICAL=A0A1D5PXC2-1" }, "locus": { "chromosome": "14", "start_pos": 4985696, "end_pos": 4979435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042465.1", "url": "https://www.ensembl.org/id/ENSGALT00010042465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024955.1", "url": "https://www.ensembl.org/id/ENSGALP00010024955.1" } ] } }, { "isoform_ac": "A0A8V0Z229-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z229/entry", "sequence": { "sequence": "MSQSDNSFEPNVIDDEMLQKAVEEQWPEDIRKLAKAEGINFKDVMELQLSFRNILQIDNLWQFENLTKLQLDNNIIEKIEALESLVHLVWLDLSFNNIEVIEGLDTLVKLQDLSLYNNRISKIEHMDTLQELQIFSIGKNNLTTLENVVYLRKFKNLHTLNLTGNPFCNEEQYMLFVVAHLPGLVYLDFKLVSDTTREVAISNYHYLTDLLEHEEAQALAQLEEKQAQQKELEYHKRLDEIHHASSHDTAESMRAEYNEDILQLSETLMTLEMQMVDQLEELIKEFERNIAVITSTFIENVKGMMTQCRDLENRHHEKLLEISISALEKSLKNELDEELPDDVREFLVDKNTIVNMVNKSHNIHLLKISMRECDILLNMYHWEASVKEKALQNEIDRNRNRIKEIFQYIDDLQEQLDNTQIPDPTE", "length": 426, "header": "tr|A0A8V0Z229-1|A0A1D5PXC2_CHICK Computationally mapped isoform of Dynein regulatory complex subunit 3 OS=Gallus gallus OX=9031 GN=DRC3 PE=3 SV=1 CANONICAL=A0A1D5PXC2-1" }, "locus": { "chromosome": "14", "start_pos": 4993697, "end_pos": 4979435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042472.1", "url": "https://www.ensembl.org/id/ENSGALT00010042472.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024962.1", "url": "https://www.ensembl.org/id/ENSGALP00010024962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GFT3-1", "protein_name": "Dynein regulatory complex subunit 3", "gene_name": "Drc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRPFDSMDPKVMDDDMLKVAVVEQGPQEEAGQLAKQEGILFKDVRSLQLDFRNILRIDNLWQFENLQKLQLNNNIIERIEGLENLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRIAKIDSLDALVKLQVLSLGNNQIGNIMNIIYLRQFSCLRTLTLSENPIAEAEEYKEFIYAYLPDLVYLDFRRIDEQAREASKLKHQYSIDEMKHREALMRARLEDEKAQRQMLEEHKLAFIERLNGPFLFNSMYSEDVEGNKLSSLPGVDELLETYKDKFVIICLNIFEYGLKQQEKRMAELDTFNECIQDAIRENQEQGKLKVTKFEEKHLLNLNAIREESDLPNIEKKLIECSDDITDLFNVLMTLEMQLVEQLEETINIFERNITDMVGLFIENVQSLMAQCRDLENHHHEKILEIAINTLEKILKNEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGINSWCAHLLDKIHREEIVRNRKRVKEINQYIDHMQSELDNLECGDIIDI", "length": 524 }, "evidence": [ { "id": "A0A1D5PXC2", "url": "https://omabrowser.org/oma/group/A0A1D5PXC2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XI54-1", "protein_name": "Dynein regulatory complex subunit 3", "gene_name": "Drc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRPYDSMEPKVMDDDMLKVAVGEQGPQEEAGQLAKQEGILFKDVLALQLDFQNILRIDNLWQFENLRKLQLNNNIIERIEGLENLTHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSHNRISKIDSLDPLVNLQVLSLGNNQINNMMNIIYLRRFPCLRTLSLSGNPVSEAEEYKVFIYAYLPDLVYLDFRRVDEQAREVAKMKHQYSIDELKHREALMQIRLEEEQAKQQKLAEHKMAFVEHLNGPFLFDSMYSDDVEGNKLSYLPGVGELLEAYKDKFVIICLNIFEYGLSQQEKRKIELDTFNECIQEAIQENQDQGKLKIAKFEEKHLLNLNAIREESDLFTMEQKLTECNESITELFNTLMILEMQLVEQLEETINVFERNITDLVGLFIENVQSLIAQCRDLENHHHEKLLEIAINTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGVNSWCAHLVDKIHKDEIMRNRKRVKEINQFVDHMQSELDNLECGDIID", "length": 523 }, "evidence": [ { "id": "A0A1D5PXC2", "url": "https://omabrowser.org/oma/group/A0A1D5PXC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D5E4-1", "protein_name": "Dynein regulatory complex subunit 3", "gene_name": "Drc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRPYDSMEPKVMDDDMLKAAVGEQGPQEEAGQLAKQEGILFKDVLSLQLDFQNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKLQVLSLGNNQISNMMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREMAKMKHQYSIDELKHREAQLQMKLEEEQAKQEKLEEHKMAFVEHLNGPFLFDSMYSEDVEGNKLSYLPGVRELLEAYKDKFVIICLNIFEYGLNQQEKRKVELDTFNECIQEAILENQDQGKLKVAKFEEKHLLNLNAIREETDLSNIEKKLTECTESIGELFNTLMILEMQLVEQLEETINIFERNITDLVGLFIENVQSLIAQCRDLENHHHEKLLEIAINTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGINSWCAHLVDKIHKDEIMRNRKRVKEINQFVDHMQSELDNLECGDIID", "length": 523 }, "evidence": [ { "id": "A0A1D5PXC2", "url": "https://omabrowser.org/oma/group/A0A1D5PXC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H069-1", "protein_name": "Dynein regulatory complex subunit 3", "gene_name": "DRC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTRINSWCTRLIDRIHKDEIMRNRKRVKEINQYIDHMQSELDNLECGDILD", "length": 523 }, "evidence": [ { "id": "A0A1D5PXC2", "url": "https://omabrowser.org/oma/group/A0A1D5PXC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VL65-1", "protein_name": "Dynein axonemal assembly factor 1 homolog", "gene_name": "TbCMF46", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDEPVSSQPGEDAVEETEEEPLRGFLEEINCPEPGIIDRQMIETAYLEEGKKGEARRLHQLEPVVYDRITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPIAKQPDFPLSLYVIAILPQLNYYEYVFIKTETREEAQKRFYRELREIEDKQEREIQGLETEAREMAEADRLASSFVEHLDGMQLYDSLWRDDEDGRILMLVGAPAQELCEEYSKDVYELTQQIYRLGLERFGERDEEIRDFNANLHEGQEELQAQGQRQIEDFLEYKERIFDEMRLKWRELDQRDDDLEQLQAQLDTLTANFEDSLNELWESLMAQELHLHEAVEDSTLKFNRKISDLMSNFVEQAQVIFLQLRDLCSYFADNMTDIVNQFLSTKLARNELNTIPEELKQCVDDREAVLQLVEGMRTTHTSRVDKREDRLAQRSRQFIDDMITNLNNKEVDRHRAKILEINSFMEMMTEALANLPGELHQEAPSD", "length": 566 }, "evidence": [ { "id": "A0A1D5PXC2", "url": "https://omabrowser.org/oma/group/A0A1D5PXC2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2" } ], "pmid": "" }, { "name": "axonemal doublet microtubule", "id": "GO:0097545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097545", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PXC2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PXC2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXC2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PXG6-1", "uniprot_ac": "A0A1D5PXG6", "uniprot_id": "A0A1D5PXG6_CHICK", "mass": { "chemical_mass": 42697.0, "monoisotopic_mass": 42697.0 }, "refseq": { "ac": "NP_001294926", "name": "ubiquitin specific peptidase 12-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001294926" }, "gene_names": [ { "name": "USP12-like", "type": "recommended", "evidence": [ { "id": "A0A1D5PXG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6" } ] }, { "name": "USP12-like", "type": "synonym", "evidence": [ { "id": "NP_001294926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001294926" } ] } ], "protein_names": [ { "name": "ubiquitinyl hydrolase 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PXG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A1D5PXG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin specific peptidase 12-like", "type": "synonym", "evidence": [ { "id": "NP_001294926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001294926" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.10375.1, SRR13267649.187221.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001294926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001294926" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP12-like", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6", "locus": { "chromosome": "4", "start_pos": 12235851, "end_pos": 12207495, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011545", "url": "https://www.ensembl.org/id/ENSGALG00010011545" } ] } } ], "crossref": [ { "id": "A0A1D5PXG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034769", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034769", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02663", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02663", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422322", "url": "https://www.ncbi.nlm.nih.gov/gene/422322", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422322", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422322", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIECLNC", "url": "https://omabrowser.org/oma/group/QIECLNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXG6", "url": "https://www.orthodb.org/?gene=A0A1D5PXG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001294926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001294926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PXG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVLMTVRRLASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKVQPRKKESLLTCLSDLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKKQEKQNGKLQNGSIESEEGDKTDLTWVHEIFQGTLTNETRCLNCEAVSSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 369, "header": "tr|A0A1D5PXG6-1|A0A1D5PXG6_CHICK Isoform 1 of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN=USP12-like PE=3 SV=1 CANONICAL=A0A1D5PXG6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6/entry", "sequence": { "sequence": "MDVLMTVRRLASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKVQPRKKESLLTCLSDLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKKQEKQNGKLQNGSIESEEGDKTDLTWVHEIFQGTLTNETRCLNCEAVSSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 369, "header": "tr|A0A1D5PXG6-1|A0A1D5PXG6_CHICK Isoform 1 of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN=USP12-like PE=3 SV=1 CANONICAL=A0A1D5PXG6-1" }, "locus": { "chromosome": "4", "start_pos": 12233607, "end_pos": 12207610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027692.1", "url": "https://www.ensembl.org/id/ENSGALT00010027692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015872.1", "url": "https://www.ensembl.org/id/ENSGALP00010015872.1" } ] } }, { "isoform_ac": "A0A8V0YDT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT2/entry", "sequence": { "sequence": "MSSDRQLFHFQYVTFLLSNHFLLLPFNRPNMKLFVFLLFCFNQFGNTCYCNSVLQALYFCRPFREKVLAYKVQPRKKESLLTCLSDLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKKQEKQNGKLQNGSIESEEGDKTDLTWVHEIFQGTLTNETRCLNCEAGR", "length": 192, "header": "tr|A0A8V0YDT2-1|A0A1D5PXG6_CHICK Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN=USP12-like PE=3 SV=1 CANONICAL=A0A1D5PXG6-1" }, "locus": { "chromosome": "4", "start_pos": 12224028, "end_pos": 12222408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027645.1", "url": "https://www.ensembl.org/id/ENSGALT00010027645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015844.1", "url": "https://www.ensembl.org/id/ENSGALP00010015844.1" } ] } }, { "isoform_ac": "A0A8V0YIL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL7/entry", "sequence": { "sequence": "MSSDRQLFHFQYVTFLLSNHFLLLPFNRPNMKLFVFLLFCFNQFGNTCYCNSVLQALYFCRPFREKVLAYKVQPRKKESLLTCLSDLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKKQEKQNGKLQNGSIESEEGDKTDLTWVHEIFQGTLTNETRCLNCEAVSSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGRYVIFGAF", "length": 317, "header": "tr|A0A8V0YIL7-1|A0A1D5PXG6_CHICK Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN=USP12-like PE=3 SV=1 CANONICAL=A0A1D5PXG6-1" }, "locus": { "chromosome": "4", "start_pos": 12226836, "end_pos": 12222408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027719.1", "url": "https://www.ensembl.org/id/ENSGALT00010027719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015887.1", "url": "https://www.ensembl.org/id/ENSGALP00010015887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422322", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F4N9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "usp12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEILMTVRKIASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKIQPRRKESLLTCLADLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKSQERQQNGKVVQNGGSGSGGGGSGSSTGEGETEEKTQQTWVHEIFQGTLTNETRCLNCEAVSSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRLYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 383 }, "evidence": [ { "id": "A0A1D5PXG6", "url": "https://omabrowser.org/oma/group/A0A1D5PXG6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { 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"" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXG6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, 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This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A001", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A001", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A001-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A001-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQQKYRRLNKGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGPGYGSRGGYGGGGGPGYGNPGGGYGGGGGGYDGYNEGGNFGGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 386, "header": "tr|A0A1D5PXH1-1|A0A1D5PXH1_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=2 CANONICAL=A0A1D5PXH1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQQKYRRLNKGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGPGYGSRGGYGGGGGPGYGNPGGGYGGGGGGYDGYNEGGNFGGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 386, "header": "tr|A0A1D5PXH1-1|A0A1D5PXH1_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=2 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058924.1", "url": "https://www.ensembl.org/id/ENSGALT00010058924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035889.1", "url": "https://www.ensembl.org/id/ENSGALP00010035889.1" } ] } }, { "isoform_ac": "A0A8V0ZQZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ3/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRVKYFSGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGPGYGSRGGYGGGGGPGYGNPGGGYGGGGGGYDGYNEGGNFGGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 383, "header": "tr|A0A8V0ZQZ3-1|A0A8V0ZQZ3_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058900.1", "url": "https://www.ensembl.org/id/ENSGALT00010058900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035865.1", "url": "https://www.ensembl.org/id/ENSGALP00010035865.1" } ] } }, { "isoform_ac": "A0A8V0ZY63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY63/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDVATMEVVLAMAAEGVMVVVEDQDMETQVVDMEVEEEDMMATMKEAILEVVIMEAVETTMTLVTTVDSSSPITVP", "length": 344, "header": "tr|A0A8V0ZY63-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058874.1", "url": "https://www.ensembl.org/id/ENSGALT00010058874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035839.1", "url": "https://www.ensembl.org/id/ENSGALP00010035839.1" } ] } }, { "isoform_ac": "A0A8V0ZY81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY81/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGYGGGGGGGGSRGSFVFLFSFYFPITSGILPCKLW", "length": 278, "header": "tr|A0A8V0ZY81-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15450722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058894.1", "url": "https://www.ensembl.org/id/ENSGALT00010058894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035859.1", "url": "https://www.ensembl.org/id/ENSGALP00010035859.1" } ] } }, { "isoform_ac": "A0A8V0ZY96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY96/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRVKYFSGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGGGGYDGYNEGGNFGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 355, "header": "tr|A0A8V0ZY96-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058909.1", "url": "https://www.ensembl.org/id/ENSGALT00010058909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035874.1", "url": "https://www.ensembl.org/id/ENSGALP00010035874.1" } ] } }, { "isoform_ac": "A0A8V1A001-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A001/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGPGYGSRGGYGGGGGPGYGNPGGGYGGGGGGYDGYNEGGNFGGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 347, "header": "tr|A0A8V1A001-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058888.1", "url": "https://www.ensembl.org/id/ENSGALT00010058888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035853.1", "url": "https://www.ensembl.org/id/ENSGALP00010035853.1" } ] } }, { "isoform_ac": "A0A8V1A3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K0/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQREYFSGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYDGYNEGGNFGGGNYGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSGSPYGGGYGSGSGSGGYGGRRF", "length": 320, "header": "tr|A0A8V1A3K0-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058881.1", "url": "https://www.ensembl.org/id/ENSGALT00010058881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035846.1", "url": "https://www.ensembl.org/id/ENSGALP00010035846.1" } ] } }, { "isoform_ac": "A0A8V1A3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K4/entry", "sequence": { "sequence": "MAAIKEEREVEDYKRKGRRSSQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLREYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASSQRGRGGGSGNFMGRGNFGGGGGNFGRGGNFGGRGGYGGGGGGGGSRGSFGGGDGYNGFGDGGNYGGGPGYGSRGGYGGGGGPGYGNPGGGYGGGGGGYDGYNEGGNFGGEVIMEAVETTMTLVTTVDSSSPITVP", "length": 345, "header": "tr|A0A8V1A3K4-1|A0A1D5PXH1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A3 OS=Gallus gallus OX=9031 GN=HNRNPA3 PE=1 SV=1 CANONICAL=A0A1D5PXH1-1" }, "locus": { "chromosome": "7", "start_pos": 15459571, "end_pos": 15451355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058886.1", "url": "https://www.ensembl.org/id/ENSGALT00010058886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035851.1", "url": "https://www.ensembl.org/id/ENSGALP00010035851.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXH1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PXH1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 386, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PXH1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXH1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PXH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXH1" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 124, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PXN7-1", "uniprot_ac": "A0A1D5PXN7", "uniprot_id": "A0A1D5PXN7_CHICK", "mass": { "chemical_mass": 88225.0, "monoisotopic_mass": 88225.0 }, "refseq": { "ac": "XP_414728", "name": "pyridoxal-dependent decarboxylase domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414728" }, "gene_names": [ { "name": "PDXDC1", "type": "recommended", "evidence": [ { "id": "A0A1D5PXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7" } ] }, { "name": "PDXDC1", "type": "synonym", "evidence": [ { "id": "XP_414728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414728" } ] } ], "protein_names": [ { "name": "Pyridoxal-dependent decarboxylase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7/entry#names_and_taxonomy" } ] }, { "name": "pyridoxal-dependent decarboxylase domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_414728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_414728.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414728" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDXDC1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7", "locus": { "chromosome": "14", "start_pos": 82351, "end_pos": 52727, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020130", "url": "https://www.ensembl.org/id/ENSGALG00010020130" } ] } } ], "crossref": [ { "id": "A0A1D5PXN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034829", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034829", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416413", "url": "https://www.ncbi.nlm.nih.gov/gene/416413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXN7", "url": "https://www.orthodb.org/?gene=A0A1D5PXN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z632", "url": "https://www.orthodb.org/?gene=A0A8V0Z632", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z650", "url": "https://www.orthodb.org/?gene=A0A8V0Z650", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCU7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42735:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42735:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PXN7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z632", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z632", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z632-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z632-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z650", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z650", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z650-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDATLEKVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTLGSWLGLPAVPAVTLYKHEDPSLSLVAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVRYSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLGQKIFKRSLRNSDAFSETSSVSHCDDMEKMDQRSPTLSPGQEQRPLEPEKTELLPKVVPQATNKDTEDIQSSKSLNDCTSVEEQGSQR", "length": 791, "header": "tr|A0A1D5PXN7-1|A0A1D5PXN7_CHICK Isoform 1 of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=3 CANONICAL=A0A1D5PXN7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7/entry", "sequence": { "sequence": "MDATLEKVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTLGSWLGLPAVPAVTLYKHEDPSLSLVAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVRYSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLGQKIFKRSLRNSDAFSETSSVSHCDDMEKMDQRSPTLSPGQEQRPLEPEKTELLPKVVPQATNKDTEDIQSSKSLNDCTSVEEQGSQR", "length": 791, "header": "tr|A0A1D5PXN7-1|A0A1D5PXN7_CHICK Isoform 1 of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=3 CANONICAL=A0A1D5PXN7-1" }, "locus": { "chromosome": "14", "start_pos": 80698, "end_pos": 55646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048626.1", "url": "https://www.ensembl.org/id/ENSGALT00010048626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028717.1", "url": "https://www.ensembl.org/id/ENSGALP00010028717.1" } ] } }, { "isoform_ac": "A0A8V0Z632-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z632/entry", "sequence": { "sequence": "MDATLEKVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLGQKIFKRSLRNSDAFSETSSVSHCDDMEKMDQRSPTLSPGQEQRPLEPEKTELLPKVVPQATNKDTEDIQSSKSLNDCTSVEEQGSQR", "length": 713, "header": "tr|A0A8V0Z632-1|A0A8V0Z632_CHICK Computationally mapped isoform of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=1 CANONICAL=A0A1D5PXN7-1" }, "locus": { "chromosome": "14", "start_pos": 80698, "end_pos": 55646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048621.1", "url": "https://www.ensembl.org/id/ENSGALT00010048621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028712.1", "url": "https://www.ensembl.org/id/ENSGALP00010028712.1" } ] } }, { "isoform_ac": "A0A8V0Z650-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z650/entry", "sequence": { "sequence": "MQVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTLGSWLGLPAVPAVTLYKHEDPSLSLVAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVRYSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLGQKIFKRSLRNSDAFSETSSVSHCDDMEKMDQRSPTLSPGQEQRPLEPEKTELLPKVVPQATNKDTEDIQSSKSLNDCTSVEEQGSQR", "length": 786, "header": "tr|A0A8V0Z650-1|A0A8V0Z650_CHICK Computationally mapped isoform of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=1 CANONICAL=A0A1D5PXN7-1" }, "locus": { "chromosome": "14", "start_pos": 80698, "end_pos": 53496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048636.1", "url": "https://www.ensembl.org/id/ENSGALT00010048636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028727.1", "url": "https://www.ensembl.org/id/ENSGALP00010028727.1" } ] } }, { "isoform_ac": "A0A8V0ZCU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU7/entry", "sequence": { "sequence": "MDATLEKVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTLGSWLGLPAVPAVTLYKHEDPSLSLVAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVRYSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLVHVKSGIFLWNSWWQPCLSQEVGTR", "length": 728, "header": "tr|A0A8V0ZCU7-1|A0A8V0ZCU7_CHICK Computationally mapped isoform of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=1 CANONICAL=A0A1D5PXN7-1" }, "locus": { "chromosome": "14", "start_pos": 79829, "end_pos": 55646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048625.1", "url": "https://www.ensembl.org/id/ENSGALT00010048625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028716.1", "url": "https://www.ensembl.org/id/ENSGALP00010028716.1" } ] } }, { "isoform_ac": "A0A8V0ZCV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV3/entry", "sequence": { "sequence": "MQQVVDPTLAEMGKNLNEAMKMLEDSQRKVEEENEKKYARKDIPGPLQGSGQDMVSILQLVQNLMHGEEEEESSQAYRLQNVGEQGHMALLGHSLAAYISVLDKERLRKLTTRILSDTTLWLCRLFRYENGSAYYHEDDREGLLKICRLVIHTCYEDYTVEGFNVLCTKQPVIYISSAARTGLGQALCNQLGLPLSCMCRVPCNTMFGSQHQMDVALLDRLIKDDVECGKLPLLLVANAGTPGAGHTDKLGRLKELCEQYNMWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTLGSWLGLPAVPAVTLYKHEDPSLSLVAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQRLLENLKNLDFIKTSVEDELSSPVVVFKFFQKYLNRDLTPHAAQTSAIQHPVISNEGHIYDTFNQWLGDQLAQMVPASGIDVVELEDEGTCVRFSPLMTSAVLGTEIQDVDQLVDCLKMKIPVLTSTLQLREEFEQEVRRTVGLLYIEDLSWPGLGVVSYHSDEKNNDNQEKELEKINTELLKKLNELESDLTFSLGPEFGGQKNCVYIGMVTEDLDVSELVETIAATGREIEENSRLLENMTEVVRKGIQEAQLQLQKANEERLLEEGLLRQIPVVGSVLNWFSPFQASPKGRTFNLTAGSLESTESTYVSKAQGTGITPPPTPTSSLTKQKHLGQKIFKRSLRNSDAFSETSSVSHCDDMEKMDQRSPTLSPGQEQRPLEPEKTELLPKVVPQATNKDTEDIQSSKSLNDCTSVEEQGSQR", "length": 785, "header": "tr|A0A8V0ZCV3-1|A0A8V0ZCV3_CHICK Computationally mapped isoform of Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDXDC1 PE=1 SV=1 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"AF-A0A1D5PXN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 791, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PXN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXN7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7" }, { "id": "PF22937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDXDC1-like third", "eco_id": "ECO_0000259", "start_pos": 500, "end_pos": 605, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN7" }, { "id": "PF22930", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22930" } ], 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXS7", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000041221", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "A0A1D5PXS7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGLCKNFARAFPLLCFPSACDRPRKRTRPPPASNRNHETLSHCGGNHLCIPVTNPCFSFLSFHYCFRHPTSHPQA", "length": 76, "header": "tr|A0A1D5PXS7-1|A0A1D5PXS7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A1D5PXS7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXS7/entry", "sequence": { "sequence": "MYGLCKNFARAFPLLCFPSACDRPRKRTRPPPASNRNHETLSHCGGNHLCIPVTNPCFSFLSFHYCFRHPTSHPQA", "length": 76, "header": "tr|A0A1D5PXS7-1|A0A1D5PXS7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A1D5PXS7-1" }, "locus": { "chromosome": "W", "start_pos": 2946168, "end_pos": 2945941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032617.1", "url": "https://www.ensembl.org/id/ENSGALT00010032617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019328.1", "url": "https://www.ensembl.org/id/ENSGALP00010019328.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PY53-1", "uniprot_ac": "A0A1D5PY53", "uniprot_id": "A0A1D5PY53_CHICK", "mass": { "chemical_mass": 19063.0, "monoisotopic_mass": 19063.0 }, "refseq": { "ac": "NP_001239017", "name": "probable peptide chain release factor C12orf65 homolog, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" }, "gene_names": [ { "name": "C12orf65", "type": "recommended", "evidence": [ { "id": "A0A1D5PY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY53" } ] }, { "name": "C12orf65", "type": "synonym", "evidence": [ { "id": "NP_001239017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" } ] }, { "name": "C15H12ORF65", "type": "synonym", "evidence": [ { "id": "NP_001239017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" } ] } ], "protein_names": [ { "name": "Mitochondrial translation release factor in rescue", "type": "recommended", "evidence": [ { "id": "A0A1D5PY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY53/entry#names_and_taxonomy" } ] }, { "name": "probable peptide chain release factor C12orf65 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001239017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" } ] }, { "name": "probable peptide chain release factor C12orf65, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001239017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932135.1, HAEK01167589.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992470, SAMEA103992533 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000260.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239017" } ] }, { "annotation": "Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY53", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY53#function" }, { "database": "UniProtKB", "id": "ARBA00055584", "url": "https://www.uniprot.org/uniprotkb/ARBA00055584#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PY53", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY53", "locus": { "chromosome": "15", "start_pos": 5072327, "end_pos": 5074822, "strand": "+", "evidence": [ { "database": "Ensembl 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025004130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004130" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYD8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC420480", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYD8", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000039186", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420480", "url": "https://www.ncbi.nlm.nih.gov/gene/420480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"url": "https://www.uniprot.org/uniprotkb/A0A1D5PYD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYD8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 } ] }, 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003642917.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642917" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLPPR3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6", "locus": { "chromosome": "28", "start_pos": 3259118, "end_pos": 3263560, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027421", "url": "https://www.ensembl.org/id/ENSGALG00010027421" } ] } } ], "crossref": [ { "id": "A0A1D5PYJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PYJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038529", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858410", "url": "https://www.ncbi.nlm.nih.gov/gene/100858410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858410", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHPVVQA", "url": "https://omabrowser.org/oma/group/HHPVVQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYJ6", "url": "https://www.orthodb.org/?gene=A0A1D5PYJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-419408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642917", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISPKDKAKAPKDSMTLLPCFYFVELPIVASSIVTLYFLELTDLFKPAKVGFQCHDRALSMPYVESSEELIPLLMLLSLAFAAPAASIMLGEGLVYCLQSRLKGRAGTEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHAPFFLTVCKPNYTLLGTPCDANPYITQDICAGTDKHAILSARKTFPSQHATLSAFAAVYVSMYFNSTISDSTKLLKPILVFAFAIAAGICGLTQITQYRSHPTDVYVGFLIGAGIAAYLAYHAVGNFRAPTERVPVPTPAKDALRVLTQRGHDAVYQQNKSVSTDELTPRLEEEEAAVRPVPRDKNSLGSLKRASVDVDLLAPRSPMAKENMVTFSNTLPRVSTPSMEDAARRHMTIHVPLDASRSKQLISEWKQKAMEGRGAEEVDEEVPPALYPTVQARPERTALGPRVLLPPRPGAAPLVHIPEESAAGGAGAVRAKWVMVAEKSAPRAANPPRLMQVIAMSKPQSAAPTTPKHSETSSSSTSSDSSQYRSPSERDSSSIVTIDAHAPHHPVVHLNAGNGPWEWKAAPKGAEDGYELGEVGKEFRAFHPAKSAGVSPGSSLSDVEQDEPRYGSLAAIHGAPGGAERGDVGEGLLGAASREATLRRKAAERDVLTDCDADGFYRKLPAGRRFKD", "length": 670, "header": "tr|A0A1D5PYJ6-1|A0A1D5PYJ6_CHICK Isoform 1 of Phospholipid phosphatase-related protein type 3 OS=Gallus gallus OX=9031 GN=PLPPR3 PE=3 SV=1 CANONICAL=A0A1D5PYJ6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PYJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6/entry", "sequence": { "sequence": "MISPKDKAKAPKDSMTLLPCFYFVELPIVASSIVTLYFLELTDLFKPAKVGFQCHDRALSMPYVESSEELIPLLMLLSLAFAAPAASIMLGEGLVYCLQSRLKGRAGTEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHAPFFLTVCKPNYTLLGTPCDANPYITQDICAGTDKHAILSARKTFPSQHATLSAFAAVYVSMYFNSTISDSTKLLKPILVFAFAIAAGICGLTQITQYRSHPTDVYVGFLIGAGIAAYLAYHAVGNFRAPTERVPVPTPAKDALRVLTQRGHDAVYQQNKSVSTDELTPRLEEEEAAVRPVPRDKNSLGSLKRASVDVDLLAPRSPMAKENMVTFSNTLPRVSTPSMEDAARRHMTIHVPLDASRSKQLISEWKQKAMEGRGAEEVDEEVPPALYPTVQARPERTALGPRVLLPPRPGAAPLVHIPEESAAGGAGAVRAKWVMVAEKSAPRAANPPRLMQVIAMSKPQSAAPTTPKHSETSSSSTSSDSSQYRSPSERDSSSIVTIDAHAPHHPVVHLNAGNGPWEWKAAPKGAEDGYELGEVGKEFRAFHPAKSAGVSPGSSLSDVEQDEPRYGSLAAIHGAPGGAERGDVGEGLLGAASREATLRRKAAERDVLTDCDADGFYRKLPAGRRFKD", "length": 670, "header": "tr|A0A1D5PYJ6-1|A0A1D5PYJ6_CHICK Isoform 1 of Phospholipid phosphatase-related protein type 3 OS=Gallus gallus OX=9031 GN=PLPPR3 PE=3 SV=1 CANONICAL=A0A1D5PYJ6-1" }, "locus": { "chromosome": "28", "start_pos": 3262328, "end_pos": 3259746, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066484.1", "url": "https://www.ensembl.org/id/ENSGALT00010066484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040734.1", "url": "https://www.ensembl.org/id/ENSGALP00010040734.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100858410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858410", "resource": "KEGG Pathway" }, { "id": "R-GGA-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BF79-1", "protein_name": "Phospholipid phosphatase-related protein type 3", "gene_name": "PLPPR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MISTKEKNKTPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETSEELIPLLMLLSLAFAAPAASIMVGEGVLYCLQSRLWGRGGGPGGAEGSIHAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHAPFFLTVCKPNYTLLGTSCEANPYITQDICSGHDAHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTKLLKPSLVFSFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPSEKPVAPAPAKDALRALTQRGHDSVYQQNKSVSTDELGPPGRLEGVPRPVARDKTSLGSLKRASVDVDLLAPRSPMGKENMVTFSHTLPRVSTPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDEASPGHLRPPAEPMAEEEEEEEEEDEEEDEEEEGEEGGPAPPSLYPTVQARPGLGPRVILPPRAGPQPLVHIPEEGAQAAASLSPKSSAAVRAKWLMMAEKSGAPMAAASTQPRVANPPRLLQVIAMSKAPGGPGPKVAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGNGPWEWKAAGGGAKGAECEGTYELGDLARGFRGGPKPSGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGMADGALGPASRESTLRRKAGSLALGEREAMEAEAEGYYRKLQAARRFKD", "length": 731 }, "evidence": [ { "id": "A0A1D5PYJ6", "url": "https://omabrowser.org/oma/group/A0A1D5PYJ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TJ85-1", "protein_name": "Phospholipid phosphatase-related protein type 3", "gene_name": "PLPPR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MISTKEKNKSPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETSEELIPLLMLLSLAFAAPAASIMVGEGMLYCLQSRLWGRSGGPGGPEGSIHAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHAPFFLTVCKPNYTLLGTSCEANPYITQDICSGHDTHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTKLLKPILVFSFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAERPVAVVPTKDALRALTQRGHDSVYQQNKSVSTDELGPPSRLEGVPRPVARDKTSLGSLKRASVDVDLLAPRSPMGKENMVTFSHTLPRVSTPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDEGSPAHLRAPAEPMAEEEEEEEEEEEEEEEEGEEGGPAPPSLYPTVQARPGLGPRVILPPRPGPQPLVHIPEEGAQAAAGLSPNSSAAVRAKWLMMAEKSGAAVATASAQPRMANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGNGPWEWKAAGVGAKVVEGEGGYELGDLARSFRGGAKPPGISPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGAVDGVLGPGSRESTLRRKAGPALGDREAAEAEAESYYRKMQAARRFKD", "length": 728 }, "evidence": [ { "id": "A0A1D5PYJ6", "url": "https://omabrowser.org/oma/group/A0A1D5PYJ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6T4P5-1", "protein_name": "Phospholipid phosphatase-related protein type 3", "gene_name": "PLPPR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISTKEKNKIPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIMVAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKDALRALTQRGHDSVYQQNKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSGAGVRAKWLMMAEKSGAAVANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHHPVVHLSAGGAPWEWKAAGGGAKAEADGGYELGDLARGFRGGAKPPGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAEREAEAEAEGYFRKMQARRFPD", "length": 718 }, "evidence": [ { "id": "A0A1D5PYJ6", "url": "https://omabrowser.org/oma/group/A0A1D5PYJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 292 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"uniprot_canonical_ac": "A0A1D5PYM3-1", "uniprot_ac": "A0A1D5PYM3", "uniprot_id": "A0A1D5PYM3_CHICK", "mass": { "chemical_mass": 35238.0, "monoisotopic_mass": 35238.0 }, "refseq": { "ac": "XP_001232812", "name": "multiple myeloma tumor-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232812" }, "gene_names": [ { "name": "C1orf35", "type": "recommended", "evidence": [ { "id": "A0A1D5PYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3" } ] }, { "name": "C1orf35", "type": "synonym", "evidence": [ { "id": "XP_001232812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232812" } ] } ], "protein_names": [ { "name": "Chromosome 1 open reading frame 35", "type": "synonym", "evidence": [ { "id": "A0A1D5PYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3/entry#names_and_taxonomy" } ] }, { "name": "multiple myeloma tumor-associated protein 2", "type": "synonym", "evidence": [ { "id": "XP_001232812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232812" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001232812.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232812" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PYM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf35", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3", "locus": { "chromosome": "2", "start_pos": 2383757, "end_pos": 2380311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026076", "url": "https://www.ensembl.org/id/ENSGALG00010026076" } ] } } ], "crossref": [ { "id": "A0A1D5PYM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PYM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037519", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769525", "url": "https://www.ncbi.nlm.nih.gov/gene/769525", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769525", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769525", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THHRVDR", "url": "https://omabrowser.org/oma/group/THHRVDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYM3", "url": "https://www.orthodb.org/?gene=A0A1D5PYM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14580:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14580:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PYM3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGSSRGGVRGGQDQFSWEDVKTDKQRENYLGNSLMAPVGRWQKGKDLTWYAKGKQEPAPLSREEELAAVRLAEQEAMMAALGYKNVKRQPTGLSKEDLAEVCKRDSTERAEDVDRLVGLGSSSGSAGRVMLSKEDKEAAKMGLSVFTHQKVCSSPEASGSKRKQDKEEKAEEKRTESSKKSKKEKKKKKKKKHKKEKKKDKHHKRDDTPSSSASSPDQDERRHRRKAQDRPASHSGRPEASRHRHRRDTDSSHSSGASGRSPSSRRRRARSRSRNGQRHPSPRHKGRRRSRSRSRSHRARQRHDTDSDD", "length": 310, "header": "tr|A0A1D5PYM3-1|A0A1D5PYM3_CHICK Isoform 1 of Chromosome 1 open reading frame 35 OS=Gallus gallus OX=9031 GN=C1orf35 PE=1 SV=2 CANONICAL=A0A1D5PYM3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PYM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYM3/entry", "sequence": { "sequence": "MFGSSRGGVRGGQDQFSWEDVKTDKQRENYLGNSLMAPVGRWQKGKDLTWYAKGKQEPAPLSREEELAAVRLAEQEAMMAALGYKNVKRQPTGLSKEDLAEVCKRDSTERAEDVDRLVGLGSSSGSAGRVMLSKEDKEAAKMGLSVFTHQKVCSSPEASGSKRKQDKEEKAEEKRTESSKKSKKEKKKKKKKKHKKEKKKDKHHKRDDTPSSSASSPDQDERRHRRKAQDRPASHSGRPEASRHRHRRDTDSSHSSGASGRSPSSRRRRARSRSRNGQRHPSPRHKGRRRSRSRSRSHRARQRHDTDSDD", "length": 310, "header": "tr|A0A1D5PYM3-1|A0A1D5PYM3_CHICK Isoform 1 of Chromosome 1 open reading frame 35 OS=Gallus gallus OX=9031 GN=C1orf35 PE=1 SV=2 CANONICAL=A0A1D5PYM3-1" }, "locus": { "chromosome": "2", "start_pos": 2383661, "end_pos": 2381183, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063566.1", "url": "https://www.ensembl.org/id/ENSGALT00010063566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039236.1", "url": "https://www.ensembl.org/id/ENSGALP00010039236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769525", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769525", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TZL9-1", "protein_name": "Multiple myeloma tumor-associated protein 2 isoform X1", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGSSRSGGVRGGQDQFNWDDVKVDKHRENYLGNSLMAPVGRWQKGKDLTWYAKDKKSGKALTKEQEMEAVREAEHEAMLAALGHKTIKRQPTGLTKEDLADVCRREGEGEERDVDRVSGLGSSSITNLTDRKKPVRGQRRTANLIKQIKGPTAKRKTKRKRRARRRKRKRKRKGSTEAGANLQIPTLKSTVKGGEKIPGTTTVLIHQGAVRVEPGPVTGIQEGGQRPSAGPRPPLHSATAADTTPTHPLRDTAQGGGPLNKLTGGAMIAAQTTDARFYPVFQTQTSHGEQIYCQHIYLDAVQLNILQVYTLYFAACAFKGVSSLKNVYLLTFKLL", "length": 336 }, "evidence": [ { "id": "A0A1D5PYM3", "url": "https://omabrowser.org/oma/group/A0A1D5PYM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5M9I6-1", "protein_name": "Multiple myeloma tumor-associated protein 2 homolog", "gene_name": "Mmtag2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGSSRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKDRAPCTGPSREEELAAVREAEREALLAALGYKNVRKQPTGLSKEDFVEICKREGGDPEEKGVDRLLGLGSASGSAGRVALSREDKEAAKLGLSVFTHHRVDSEGPSTAPSATRKKPRAEDKAELDAESHKKSKKEKKKKKKKHKKHKKKKDKEHKREADSCSSSPSPARPRRQRHSDFSPCYKRKREHSQDSGRNPSHRRQDRSSDD", "length": 260 }, "evidence": [ { "id": "A0A1D5PYM3", "url": "https://omabrowser.org/oma/group/A0A1D5PYM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99LX5-1", "protein_name": "Multiple myeloma tumor-associated protein 2 homolog", "gene_name": "Mmtag2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGSNRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKDRAPCTGPSREEELAAVREAEREALLAALGYKNVRKQPTGLSKEDFVEICKREGGDPEEKGVDRLLGLGSASGSAGRVALSREDKEAAKLGLSVFTHHRVDSEGPSTAPTAPRKKPRAEDKVEPDAESHKKSKKEKKKKKKKHKKHKKKKDKEHKREADSCSSSPSPPRPRHQRHSDFSPCSKRKREHSQDSGRNPSRRRQDRSSDD", "length": 260 }, "evidence": [ { "id": "A0A1D5PYM3", "url": "https://omabrowser.org/oma/group/A0A1D5PYM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BU76-1", "protein_name": "Multiple myeloma tumor-associated protein 2", "gene_name": "MMTAG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGSSRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAGPSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSEA", "length": 263 }, "evidence": [ { "id": "A0A1D5PYM3", "url": 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133819" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM155B", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05", "locus": {} } ], "crossref": [ { "id": "A0A1D5PZ05", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZ05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041437", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041437", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769051", 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"categories": [ "Protein Classification" ] }, { "id": "XP_015133819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRGAWMYPRGGAGGGAVCCAPRRSDKPVADPERAQKWRLSLASLLFFTVLLSDHLWLCAGAKLRARERSGAGRPRGRTPRALQEPPAGSCEAFLGNLSRAPGPAPCPAARADLDSACARLHSLQRLLGSFAGVPLRSPPATALFSSPSSKRNFLQAYFRNFNLSFCDTYTIWDLLREMGGPDSLDCSVENLMVDLVAAAAGALGGEACSSCVQAYQRLDQHAQEKYEEFDLLLEKYLQSDEYSVRSCIRDCKAVYKAWLCSEYFNVTQQQCRHRIPCKQYCLEVQTRCPFVLPDNDELIYGGLPGFICTGLLESQLPEEEAKCCEVQWDSCDHPPDSSSDTSPKSTASESLHYHHHDPHLHHQRQNHYHLYHHHQYHHSPSLLPVSAGSRLGSSRIRLCVLVLMLLHTMVSFSSVHSGGGGLGPEALPSLDESVARDE", "length": 439, "header": "tr|A0A1D5PZ05-1|A0A1D5PZ05_CHICK Isoform 1 of NALCN channel auxiliary factor 2 OS=Gallus gallus OX=9031 GN=FAM155B PE=3 SV=1 CANONICAL=A0A1D5PZ05-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05/entry", "sequence": { "sequence": "MIRGAWMYPRGGAGGGAVCCAPRRSDKPVADPERAQKWRLSLASLLFFTVLLSDHLWLCAGAKLRARERSGAGRPRGRTPRALQEPPAGSCEAFLGNLSRAPGPAPCPAARADLDSACARLHSLQRLLGSFAGVPLRSPPATALFSSPSSKRNFLQAYFRNFNLSFCDTYTIWDLLREMGGPDSLDCSVENLMVDLVAAAAGALGGEACSSCVQAYQRLDQHAQEKYEEFDLLLEKYLQSDEYSVRSCIRDCKAVYKAWLCSEYFNVTQQQCRHRIPCKQYCLEVQTRCPFVLPDNDELIYGGLPGFICTGLLESQLPEEEAKCCEVQWDSCDHPPDSSSDTSPKSTASESLHYHHHDPHLHHQRQNHYHLYHHHQYHHSPSLLPVSAGSRLGSSRIRLCVLVLMLLHTMVSFSSVHSGGGGLGPEALPSLDESVARDE", "length": 439, "header": "tr|A0A1D5PZ05-1|A0A1D5PZ05_CHICK Isoform 1 of NALCN channel auxiliary factor 2 OS=Gallus gallus OX=9031 GN=FAM155B PE=3 SV=1 CANONICAL=A0A1D5PZ05-1" }, "locus": { "chromosome": "4", "start_pos": 1077004, "end_pos": 1061498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042426.1", "url": "https://www.ensembl.org/id/ENSGALT00010042426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024916.1", "url": "https://www.ensembl.org/id/ENSGALP00010024916.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769051", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769051", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AWH2-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "nalf2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MITGAWRCGRKLDAELEICRVTEPIDKPCAESEKVQRWRMSLASLLFFTALLSDHLWLCAGGKLRSRDRTHRRTWNNASHDAQTGLRDEDCGVLLSNLTENGPDCVEADARRRAPLESACSTLYRQKSGSVSSSYSVTVPTVSPHAFLEYFRNFSLSFCDALTIADLLESMTSPDGLNCSLTHIIRDLFSGGPEDGDACSACVHAYTRLDQHAQEKYEEFDALTRKYMADDYSVRAQTHLCQVVYKAWLCAEYFPVPQRQCVRWLPCRHYCGEVTATCPFILPDNDRLLYAGSPSFLCAGFQEEYLSSQGPDCCDVRWSGCDSAVGAACALTHLPGSFSFHRRLSSGAMSCTNRLHGSKLKLCVLVLFLLHTFISITTLQHCSTGSLEAIVPLEEVPMREE", "length": 401 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2BDP1-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "Nalf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRQSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPPPPPSPGEPSASSGTCGPRYSNLTKAAPAAGSGPVCNGVPEPTGLDAACTKLESLQRLFEPTTPAPPLRPPDSPSRAPEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGTWEACSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQNWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLMDTSPKRPETKCCDVQWVSCESEKKKFKDSEPPKTHHQQFHHSYFHHYHHQYHHYHPRHEPPSRVSNKPSLLPVSGGSRLSPSRIRLCVLVLILLHTVVSFSSSQSGGGLGLETLPALEEGLTQEE", "length": 471 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A4E6-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "Nalf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRQSDKPCADSERAQRWRLSLASLLFFTVLLTDHLWLCAGARPRARELSSAMRPPWGAGRERQPVPRRAVLPLPPPSPGEPSASSGTCGPRYSNLTKAAPAAGSGPVCDGVPEPTGLDAACTKLESLQRLFEPTTPAPPLRPPDSPSRAPEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGTWEACSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECEHWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLIDTSPKRPETKCCDVQWVSCESEKKKFKDSEPPKTHHQQFHHSYFHHYHQQYHHYHPRHEPPSRVSNKPSLLPVSGGSRLSPSRIRLCVLVLMLLHTVVSFSSSQGGGGLGLETLPALEEGLTQEE", "length": 471 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RSX6-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "NALF2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRGRELSSAMRPPWGAGRERQPVPPRAVLPLPPPGQPSAPPGTCGPRHSNLTKAAPAAGPGPDCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSPSRAPAEFPTAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGAWEVCSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRPETKCCDVQWVSCESEKKKFKETEAPKTHHQQFHHSYFHHYHQQYHHYHPRHDPPGRLSHKPSLLPVSGSSRLSPSRIRLYVLVLMLLHTMVSFSSSQGGGGPGLEALPALDEGLTREE", "length": 470 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X7U0-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "NALF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPLPPPPPPPGQPSAPPGTCGPRYSNLTKAAAAAGPGPDCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSPSRAPAEFPTAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDNLLGDLLAVVASPGSGAWEVCSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRPETKCCDVQWISCESEKKFKESEAPKTHHQQFHHSYFHHYHQQYHHYHPRHEPPGRLGHKPSLLPVSGGSRLSSSRIRLYILVLVLLHTMVSFSSSQSGGGPGLEALPALDEGLAREE", "length": 473 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75949-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "NALF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPLPPPPPGEPSAPPGTCGPRYSNLTKAAPAAGSRPVCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSLSRAPAEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLMGDLLAVVASPGSGAWEACSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRLETKCCDVQWVSCEAKKKKFKESEAPKTHQQQFHHSYFHHYHQQYHHYHPHHDPPGRVSNKPALLPVSGGSRLSPSRIRLCVLVLMLLHTVVSFSSNQGGGGLGLETLPALEEGLTREE", "length": 472 }, "evidence": [ { "id": "A0A1D5PZ05", "url": "https://omabrowser.org/oma/group/A0A1D5PZ05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ05", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZ05-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZ05-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZ05" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZ57-1", "uniprot_ac": "A0A1D5PZ57", "uniprot_id": "A0A1D5PZ57_CHICK", "mass": { "chemical_mass": 43966.0, "monoisotopic_mass": 43966.0 }, "refseq": { "ac": "XP_015142170", "name": "F-box/LRR-repeat protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142170" }, "gene_names": [ { "name": "FBXL14", "type": "recommended", "evidence": [ { "id": "A0A1D5PZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" } ] }, { "name": "FBXL14", "type": "synonym", "evidence": [ { "id": "XP_015142170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142170" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 14", "type": "recommended", "evidence": [ { "id": "A0A1D5PZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 14", "type": "synonym", "evidence": [ { "id": "A0A1D5PZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 14", "type": "synonym", "evidence": [ { "id": "XP_015142170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142170" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142170" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57", "locus": { "chromosome": "1", "start_pos": 60936388, "end_pos": 60943937, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014909", "url": "https://www.ensembl.org/id/ENSGALG00010014909" } ] } } ], "crossref": [ { "id": "A0A1D5PZ57", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZ57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032159", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032159", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427926", "url": "https://www.ncbi.nlm.nih.gov/gene/427926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427926", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQALVHI", "url": "https://omabrowser.org/oma/group/DQALVHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZ57", "url": "https://www.orthodb.org/?gene=A0A1D5PZ57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METHISCLFPELLAMIFGYLEVRDKGRAAQVCTAWRDAAYHRSVWRGVEAKLHLRRANPSLFPSLAARGIRRVQILSLRRSLSYVIQGMADIESLNLSGCYNLTDNGLGHAFVAEISSLRSLNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLSDLSLKHLARGLGRLRQLNLSFCGGISDAGLLHLSHMSSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLRSLSLCSCHISDEGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKVLNLGLWEMTESEKVR", "length": 400, "header": "tr|A0A1D5PZ57-1|A0A1D5PZ57_CHICK Isoform 1 of F-box/LRR-repeat protein 14 OS=Gallus gallus OX=9031 GN=FBXL14 PE=4 SV=2 CANONICAL=A0A1D5PZ57-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57/entry", "sequence": { "sequence": "METHISCLFPELLAMIFGYLEVRDKGRAAQVCTAWRDAAYHRSVWRGVEAKLHLRRANPSLFPSLAARGIRRVQILSLRRSLSYVIQGMADIESLNLSGCYNLTDNGLGHAFVAEISSLRSLNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLSDLSLKHLARGLGRLRQLNLSFCGGISDAGLLHLSHMSSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLRSLSLCSCHISDEGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKVLNLGLWEMTESEKVR", "length": 400, "header": "tr|A0A1D5PZ57-1|A0A1D5PZ57_CHICK Isoform 1 of F-box/LRR-repeat protein 14 OS=Gallus gallus OX=9031 GN=FBXL14 PE=4 SV=2 CANONICAL=A0A1D5PZ57-1" }, "locus": { "chromosome": "1", "start_pos": 60943905, "end_pos": 60942706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035870.1", "url": "https://www.ensembl.org/id/ENSGALT00010035870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020808.1", "url": "https://www.ensembl.org/id/ENSGALP00010020808.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427926", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KF28-1", "protein_name": "Partner of paired, isoform B", "gene_name": "Ppa", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATNTELLPFHHQTIAVLNNLNSHCGGSGSNGAATSGGAAIGGAGAGGAPSWAMDELYQQTELPGLTRTGATTTHHHLLRFTPYALHHRPPHHQLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPPVEGTHISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQKLNLGLWLVRXCVHHDCNACAAKEAARGSYNSQP", "length": 562 }, "evidence": [ { "id": "A0A1D5PZ57", "url": "https://omabrowser.org/oma/group/A0A1D5PZ57/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0ABK0L9R6-1", "protein_name": "F-box and leucine-rich repeat protein 14", "gene_name": "Fbxl14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKSPPQQHERPWRNPETFIN", "length": 402 }, "evidence": [ { "id": "A0A1D5PZ57", "url": "https://omabrowser.org/oma/group/A0A1D5PZ57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BID8-1", "protein_name": "F-box/LRR-repeat protein 14", "gene_name": "Fbxl14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKVLNLGLWQMTDSEKVR", "length": 400 }, "evidence": [ { "id": "A0A1D5PZ57", "url": "https://omabrowser.org/oma/group/A0A1D5PZ57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1E6-1", "protein_name": "F-box/LRR-repeat protein 14", "gene_name": "FBXL14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLKVLNLGLWQMTDSEKEARGDFSPLFTVRTRGSSRR", "length": 418 }, "evidence": [ { "id": "A0A1D5PZ57", "url": "https://omabrowser.org/oma/group/A0A1D5PZ57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FMW7-1", "protein_name": "RNI-like superfamily protein", "gene_name": "MKD15.20", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSVCVNEALTDDELRWVLSRLDSDKDKEVFGLVCKRWLNLQSTDRKKLAARAGPHMLRRLASRFTQIVELDLSQSISRSFYPGVTDSDLAVISEGFKFLRVLNLHNCKGITDTGLASIGRCLSLLQFLDVSYCRKLSDKGLSAVAEGCHDLRALHLAGCRFITDESLKSLSERCRDLEALGLQGCTNITDSGLADLVKGCRKIKSLDINKCSNVGDAGVSSVAKACASSLKTLKLLDCYKVGNESISSLAQFCKNLETLIIGGCRDISDESIMLLADSCKDSLKNLRMDWCLNISDSSLSCILKQCKNLEALDIGCCEEVTDTAFRDLGSDDVLGLKVLKVSNCTKITVTGIGKLLDKCSSLEYIDVRSLPHVTEVRCSEAGLEFPKCCKVNFSGSLTEPDVLL", "length": 405 }, "evidence": [ { "id": "A0A1D5PZ57", "url": "https://omabrowser.org/oma/group/A0A1D5PZ57/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZ57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 400, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZ57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZ57" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" }, { "id": "PF12937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 46, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A1D5PZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZ57" }, { "id": "PF25372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box/LRR-repeat protein 15-like leucin rich repeat", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 190, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZK7-1", "uniprot_ac": "A0A1D5PZK7", "uniprot_id": "A0A1D5PZK7_CHICK", "mass": { "chemical_mass": 43213.0, "monoisotopic_mass": 43213.0 }, "refseq": { "ac": "XP_015146784", "name": "malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146784" }, "gene_names": [ { "name": "MCAT", "type": "recommended", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ] }, { "name": "MCAT", "type": "synonym", "evidence": [ { "id": "XP_015146784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146784" } ] } ], "protein_names": [ { "name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.39", "type": "synonym", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial malonyltransferase", "type": "synonym", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7/entry#names_and_taxonomy" } ] }, { "name": "[Acyl-carrier-protein] malonyltransferase", "type": "synonym", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7/entry#names_and_taxonomy" } ] }, { "name": "malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_015146784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146784" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146784" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCAT", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7", "locus": { "chromosome": "1", "start_pos": 68598694, "end_pos": 68603495, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011916", "url": "https://www.ensembl.org/id/ENSGALG00010011916" } ] } } ], "crossref": [ { "id": "A0A1D5PZK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034275", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427934", "url": "https://www.ncbi.nlm.nih.gov/gene/427934", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427934", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427934", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AANYNCP", "url": "https://omabrowser.org/oma/group/AANYNCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZK7", "url": "https://www.orthodb.org/?gene=A0A1D5PZK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47170:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47170:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146784", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41792", "url": "https://www.rhea-db.org/rhea/41792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSWAAATWRLAGCSGRGVLRGAARRRGSSLRGGGERAASLSELLQSSVGDEEPGEGEAEGERRERRSPREGAVLLFPGQGSQFVGMGRGLLRYPGVRDMYRLAEKVLGYDLLSLCLEGPRAELDRTRHCQPAVFVASLAAVEKLNHLQPKVVESCVAAAGYSVGEFAALVFAGAMDFAEALYAVKVRAEAMQAAAEAVPSGMLSVIGGREANYKYACLEARRHCESLGIDNPVCEISNYLFPDSRVIAGHIQALEFLQKNAPKFSFTRTKMLPVSGAFHTRLMEPAVEPLAEVLKSIEIQKPLICVYSNVDSKKYMHSKHIQKLLVKQLVSPVLWEQTMHSMYQRKQGMEFPYTYEVGPGKQLGAVLRKCNLKAWRQYSHVDVTEEEEAAET", "length": 393, "header": "tr|A0A1D5PZK7-1|A0A1D5PZK7_CHICK Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Gallus gallus OX=9031 GN=MCAT PE=1 SV=3 CANONICAL=A0A1D5PZK7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7/entry", "sequence": { "sequence": "MGSWAAATWRLAGCSGRGVLRGAARRRGSSLRGGGERAASLSELLQSSVGDEEPGEGEAEGERRERRSPREGAVLLFPGQGSQFVGMGRGLLRYPGVRDMYRLAEKVLGYDLLSLCLEGPRAELDRTRHCQPAVFVASLAAVEKLNHLQPKVVESCVAAAGYSVGEFAALVFAGAMDFAEALYAVKVRAEAMQAAAEAVPSGMLSVIGGREANYKYACLEARRHCESLGIDNPVCEISNYLFPDSRVIAGHIQALEFLQKNAPKFSFTRTKMLPVSGAFHTRLMEPAVEPLAEVLKSIEIQKPLICVYSNVDSKKYMHSKHIQKLLVKQLVSPVLWEQTMHSMYQRKQGMEFPYTYEVGPGKQLGAVLRKCNLKAWRQYSHVDVTEEEEAAET", "length": 393, "header": "tr|A0A1D5PZK7-1|A0A1D5PZK7_CHICK Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Gallus gallus OX=9031 GN=MCAT PE=1 SV=3 CANONICAL=A0A1D5PZK7-1" }, "locus": { "chromosome": "1", "start_pos": 68603296, "end_pos": 68600588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028494.1", "url": "https://www.ensembl.org/id/ENSGALT00010028494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016350.1", "url": "https://www.ensembl.org/id/ENSGALP00010016350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427934", "resource": "KEGG Pathway" }, { "id": "R-GGA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZXK8-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "MCAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVRVARAAWACGWRAGGHRSTSNFPLPPPGAVDVAELLRDAAAGEEGPRVAAARRLPGQCSVLLFPGQGSQVVGMGRGLLRYPRVRELYAAARRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFCEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFTVACREAREHCRTLGIENPVCEVANFLFPDCRVISGHLEALHYLRKNSYKYHFRRTKMVPVSGAFHTRLMEPALEPLAHVLKDIDLKKPLVSVHSNVTGNKYMHPKHIRQLLVQQVVSPVKWEQTMHAIYERRKGTDFPKTFEVGPGKQLGTILKSCNLQAWKSYSHVAVLEADQDEDQNL", "length": 384 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZPF2-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "Mcat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNARVARACWAWGSWGRRPASSLREPPPDAVDVAGLLRDSSVTEEGVQEAVARRPPSRCSVLLFPGQGSQAVGMGGGLLHFPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKVRAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCRSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRKNSAKFHFRRTKMLPVSGGFHTCLMEPAVEPLMKTLGSINIKKPLVAVHSNVSGHKYTHPQHIRKLLGQQVVSPVKWEQTMHCIYERKKGMEVLQPRGCDADPFGP", "length": 352 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55DQ6-1", "protein_name": "[acyl-carrier-protein] S-malonyltransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSMNSLIGKRIALLFPGQGSQIVGMGKDLIKDFPYISKIYNHSDKILNFSISNLMFNGPSEELKQTYNTQPALLLHSFSMIKILENELGFINKNKNNNNNNEDDEFKVSSEFLKRFDFALGHSLGEYSALTTSNSIKFSDALELVRYRGQLMSKCDPGVMFALLSKKNMIESGSLLELKSIINQINNKINETSNEIMICNISNINSPNQIVISGNEIGVSKVIELAKSKKLFTKSVKLEVSAAFHSDLMIPSSDKFKLKLNTINFKQPEIDVISNVNSLPYKNNIDKTSESSIQSLLSRQLSSTVEWTSSIQYCIEKWEKENIQLKDCYFVEIGSNNVLTQLLKQIYPNSNSYNIQSSNDLINFIKEFKD", "length": 370 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IVS2-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "MCAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKSCNMQAWKSYSAVDVLQTLEHVDLDPQEPPR", "length": 390 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R3F5-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "Mcat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARVARAGWAWRSWGRRAASSLREPPPDAVDVAELLRDSSVAEEGAQEAVARRRPPSQCSVLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFSEGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCKSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSINIKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDVMQNIMDPDP", "length": 381 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T3L6-1", "protein_name": "Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "beg", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLAARRLLRSPRITGALSWSRWSSDAAKATTETSALLQNAEKRQQLLNELSEPLEQKGRPAIDPKETSVMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFSLGEITALVYADALPFDKALRLVQVRATAMQAACDQAAGAMAMTLYGPDTNLGEACARAQQWCLDKGVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVRLQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKAAQSSFNVIA", "length": 379 }, "evidence": [ { "id": "A0A1D5PZK7", "url": "https://omabrowser.org/oma/group/A0A1D5PZK7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit assembly", "id": "GO:0180026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180026", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "[acyl-carrier-protein] S-malonyltransferase activity", "id": "GO:0004314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004314", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "pmid": "" }, { "name": "RNA folding chaperone", "id": "GO:0140691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140691", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZK7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41792", "name": "", "equation": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PZK7-1", "P12276-1", "A0A8V1AKX1-1" ], "evidence": [ { "id": "41792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41792" } ] }, { "id": "R-GGA-8933547", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-977314" ], "output_participant_list": [ "R-GGA-8934586" ], "enzyme_list": [ "A0A1D5PZK7-1" ], "evidence": [ { "id": "R-GGA-8933547", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8933547" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-977314", "participant_name": "Malonyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "57384", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551112", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-GGA-8934586", "participant_name": "phospho-NDUFAB1 [mitochondrial inner membrane]", "crossref": [ { "id": "ENSGALP00010024106", "database": "ENSEMBL", "url": "" }, { "id": "E1C4C0", "database": "PRO", "url": "" }, { "id": "E1C4C0", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010041185", "database": "ENSEMBL", "url": "" }, { "id": "XP_004945320.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010017057", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PZK7", "gene_name": "MCAT", "activity": [ { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ] }, { "ec_number": "2.3.1.39", "activity": "", "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" } ] } ] }, { "uniprot_ac": "A0A8V1AKX1", "gene_name": "FASN", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "4.2.1.59", "activity": "a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O.", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "1.1.1.100", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.39", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "4.2.1.59", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "2.3.1.85", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] }, { "ec_number": "1.3.1.39", "activity": "", "evidence": [ { "id": "A0A8V1AKX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX1" } ] } ] }, { "uniprot_ac": "P12276", "gene_name": "FASN", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "4.2.1.59", "activity": "a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O.", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] }, { "ec_number": "2.3.1.85", "activity": "", "evidence": [ { "id": "P12276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12276" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZK7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 393, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZK7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZK7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1D5PZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZK7" }, { "id": "SM00827", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malonyl-CoA:ACP transacylase (MAT)", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 387, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.39", "ec_name": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "2.3.1.39", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.39" }, { "id": "2.3.1.39", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.39" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZU0-1", "uniprot_ac": "A0A1D5PZU0", "uniprot_id": "A0A1D5PZU0_CHICK", "mass": { "chemical_mass": 100187.0, "monoisotopic_mass": 100187.0 }, "refseq": { "ac": "XP_015131586", "name": "integrator complex subunit 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131586" }, "gene_names": [ { "name": "INTS6", "type": "recommended", "evidence": [ { "id": "A0A1D5PZU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ] }, { "name": "INTS6", "type": "synonym", "evidence": [ { "id": "XP_015131586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131586" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 6", "type": "synonym", "evidence": [ { "id": "A0A1D5PZU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015131586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131586" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015131586.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131586" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0", "locus": { "chromosome": "1", "start_pos": 169978670, "end_pos": 170020436, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002925", "url": "https://www.ensembl.org/id/ENSGALG00010002925" } ] } } ], "crossref": [ { "id": "A0A1D5PZU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017018", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418876", "url": "https://www.ncbi.nlm.nih.gov/gene/418876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418876", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418876", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNQNHYG", "url": "https://omabrowser.org/oma/group/LNQNHYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZU0", "url": "https://www.orthodb.org/?gene=A0A1D5PZU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7R7", "url": "https://www.orthodb.org/?gene=A0A8V0X7R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHH9", "url": "https://www.orthodb.org/?gene=A0A8V0XHH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12957:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12957:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015131586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPILLFLIDTSASMNQRTHLGTTYLDIAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITVTDGSKLTTTSGIQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVSSPESEQMTGVPVDDSAITPMCEVTGGRSYCVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPIDDGQVDITRPFGPQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWLQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADNVEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVAQETGIKVRSRSHNLSMAHRNDFQHLLQGITGEIPHRPLDFNMKEYAGFQIALLNKDLKPQTFRNAYDIPRRNLLDQLTRMRSNLLKSTRKLLKGQDEDQVHSVPIAQMGNYQEYLKQIPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVSGPQNKHKRPGEPSMQGIPKRRRCMSPLLRGRPQTPPVVNNHIGGKGPPSPITQAQLDLVKPIPIHKTSEANNEIAMDDVVENHVIDPLSSDDFPDAVDSEFSMSSSPFNSLDRSATHIEGAGHEHLGNNLNVDGFLENHDESSSKEQNTEDSLPISSTSKGKKTVPCRSSREINIELRAKIMKEIRKPGRKYERIFSLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLESFLEEIHRRSNQVNHINSS", "length": 888, "header": "tr|A0A1D5PZU0-1|A0A1D5PZU0_CHICK Isoform 1 of Integrator complex subunit 6 OS=Gallus gallus OX=9031 GN=INTS6 PE=4 SV=2 CANONICAL=A0A1D5PZU0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0/entry", "sequence": { "sequence": "MPILLFLIDTSASMNQRTHLGTTYLDIAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITVTDGSKLTTTSGIQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVSSPESEQMTGVPVDDSAITPMCEVTGGRSYCVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPIDDGQVDITRPFGPQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWLQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADNVEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVAQETGIKVRSRSHNLSMAHRNDFQHLLQGITGEIPHRPLDFNMKEYAGFQIALLNKDLKPQTFRNAYDIPRRNLLDQLTRMRSNLLKSTRKLLKGQDEDQVHSVPIAQMGNYQEYLKQIPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVSGPQNKHKRPGEPSMQGIPKRRRCMSPLLRGRPQTPPVVNNHIGGKGPPSPITQAQLDLVKPIPIHKTSEANNEIAMDDVVENHVIDPLSSDDFPDAVDSEFSMSSSPFNSLDRSATHIEGAGHEHLGNNLNVDGFLENHDESSSKEQNTEDSLPISSTSKGKKTVPCRSSREINIELRAKIMKEIRKPGRKYERIFSLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLESFLEEIHRRSNQVNHINSS", "length": 888, "header": "tr|A0A1D5PZU0-1|A0A1D5PZU0_CHICK Isoform 1 of Integrator complex subunit 6 OS=Gallus gallus OX=9031 GN=INTS6 PE=4 SV=2 CANONICAL=A0A1D5PZU0-1" }, "locus": { "chromosome": "1", "start_pos": 170020030, "end_pos": 169979155, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006804.1", "url": "https://www.ensembl.org/id/ENSGALT00010006804.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004148.1", "url": "https://www.ensembl.org/id/ENSGALP00010004148.1" } ] } }, { "isoform_ac": "A0A8V0X7R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R7/entry", "sequence": { "sequence": "MPILLFLIDTSASMNQRTHLGTTYLDIAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITVTDGSKLTTTSGIQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVSSPESEQMTGVPVDDSAITPMCEVTGGRSYCVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPIDDGQVDITRPFGPQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWLQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADNVEYGLSYSVISYLKKLSQQDLKPQTFRNAYDIPRRNLLDQLTRMRSNLLKSTRKLLKGQDEDQVHSVPIAQMGNYQEYLKQIPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVSGPQNKHKRPGEPSMQGIPKRRRCMSPLLRGRPQTPPVVNNHIGGKGPPSPITQAQLDLVKPIPIHKTSEANNEIAMDDVVENHVIDPLSSDDFPDAVDSEFSMSSSPFNSLDRSATHIEGAGHEHLGNNLNVDGFLENHDESSSKEQNTEDSLPISSTSKGKKTVPCRSSREINIELRAKIMKEIRKPGRKYERIFSLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLESFLEEIHRRSNQVNHINSS", "length": 816, "header": "tr|A0A8V0X7R7-1|A0A1D5PZU0_CHICK Computationally mapped isoform of Integrator complex subunit 6 OS=Gallus gallus OX=9031 GN=INTS6 PE=4 SV=1 CANONICAL=A0A1D5PZU0-1" }, "locus": { "chromosome": "1", "start_pos": 170020030, "end_pos": 169979155, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006809.1", "url": "https://www.ensembl.org/id/ENSGALT00010006809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004153.1", "url": "https://www.ensembl.org/id/ENSGALP00010004153.1" } ] } }, { "isoform_ac": "A0A8V0XHH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHH9/entry", "sequence": { "sequence": "MVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWLQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADNVEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVAQETGIKVRSRSHNLSMAHRNDFQHLLQGITGEIPHRPLDFNMKEYAGFQIALLNKDLKPQTFRNAYDIPRRNLLDQLTRMRSNLLKSTRKLLKGQDEDQVHSVPIAQMGNYQEYLKQIPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVSGPQNKHKRPGEPSMQGIPKRRRCMSPLLRGRPQTPPVVNNHIGGKGPPSPITQAQLDLVKPIPIHKTSEANNEIAMDDVVENHVIDPLSSDDFPDAVDSEFSMSSSPFNSLDRSATHIEGAGHEHLGNNLNVDGFLENHDESSSKEQNTEDSLPISSTSKGKKTVPCRSSREINIELRAKIMKEIRKPGRKYERIFSLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLESFLEEIHRRSNQVNHINSS", "length": 572, "header": "tr|A0A8V0XHH9-1|A0A1D5PZU0_CHICK Computationally mapped isoform of Integrator complex subunit 6 OS=Gallus gallus OX=9031 GN=INTS6 PE=4 SV=1 CANONICAL=A0A1D5PZU0-1" }, "locus": { "chromosome": "1", "start_pos": 169990561, "end_pos": 169979155, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006802.1", "url": "https://www.ensembl.org/id/ENSGALT00010006802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004146.1", "url": "https://www.ensembl.org/id/ENSGALP00010004146.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418876", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418876", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AP01-1", "protein_name": "Integrator complex subunit 6", "gene_name": "Ints6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTVSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPAEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQVLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPSMQGIPKRRRCASPLLRGRRQSPAVNSHIGGKGPPAPMTQAQPGLIKPLPLHKEATNDSVVDDVVENHVADQLSSDMTTNAMDTEFLTSPANLLEPSTNHTEALGHEHLGNNDLTVGGFLENHEESRSKEQSAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN", "length": 883 }, "evidence": [ { "id": "A0A1D5PZU0", "url": "https://omabrowser.org/oma/group/A0A1D5PZU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BF57-1", "protein_name": "Integrator complex subunit 6", "gene_name": "INTS6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPVEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPIVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAYRKDFQQLLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRRFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPNMQGVPKRRRCMSPLLRGRQQSPVVNNHIGGKGPPAPMTQAQPDLIKPLPLHKISEATNDSTMDDVVENHVADQLSSDTTPNAMEAEFSGSSPANLLERPTNHTEALGHDHLGTNDLTVGGFLENHEEPRDKEQCPEENIPASSLNRGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN", "length": 887 }, "evidence": [ { "id": "A0A1D5PZU0", "url": "https://omabrowser.org/oma/group/A0A1D5PZU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PCM2-1", "protein_name": "Integrator complex subunit 6", "gene_name": "Ints6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPPPAEEGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQVLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPSMQGIPKRRRCASPLLRGRRQSPAVNSHIGGKGPPAPMTQAQPGLIKPLPLHKEATNDSIVDDVVENHVADQLSSDMTPNAMDTEFLTSPPNLLEPSTNHTEALGHEHLGNNDLTVGGFLENHEEPRNKEQSAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN", "length": 883 }, "evidence": [ { "id": "A0A1D5PZU0", "url": "https://omabrowser.org/oma/group/A0A1D5PZU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL03-1", "protein_name": "Integrator complex subunit 6", "gene_name": "INTS6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPVEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAYRKDFQQLLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRRFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPNMQGIPKRRRCMSPLLRGRQQNPVVNNHIGGKGPPAPTTQAQPDLIKPLPLHKISETTNDSIIHDVVENHVADQLSSDITPNAMDTEFSASSPASLLERPTNHMEALGHDHLGTNDLTVGGFLENHEEPRDKEQCAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN", "length": 887 }, "evidence": [ { "id": "A0A1D5PZU0", "url": "https://omabrowser.org/oma/group/A0A1D5PZU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZU0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZU0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 888, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZU0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZU0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 492, "end_pos": 494 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZV7-1", "uniprot_ac": "A0A1D5PZV7", "uniprot_id": "A0A1D5PZV7_CHICK", "mass": { "chemical_mass": 25136.0, "monoisotopic_mass": 25136.0 }, "refseq": { "ac": "XP_004941217", "name": "claudin-23", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941217" }, "gene_names": [ { "name": "CLDN23", "type": "recommended", "evidence": [ { "id": "A0A1D5PZV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7" } ] }, { "name": "CLDN23", "type": "synonym", "evidence": [ { "id": "XP_004941217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941217" } ] } ], "protein_names": [ { "name": "Claudin 23", "type": "synonym", "evidence": [ { "id": "A0A1D5PZV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7/entry#names_and_taxonomy" } ] }, { "name": "claudin-23", "type": "synonym", "evidence": [ { "id": "XP_004941217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941217" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004941217.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941217" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLDN23", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7", "locus": { "chromosome": "4", "start_pos": 49086045, "end_pos": 49087362, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004484", "url": "https://www.ensembl.org/id/ENSGALG00010004484" } ] } } ], "crossref": [ { "id": "A0A1D5PZV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042123", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042123", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428756", "url": "https://www.ncbi.nlm.nih.gov/gene/428756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428756", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRCWQDE", "url": "https://omabrowser.org/oma/group/VRCWQDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZV7", "url": "https://www.orthodb.org/?gene=A0A1D5PZV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTPAVMIVGLVLCPCGLLLTLTGTLAPNWRQVSLIPEQPSDLILEQGIWDLCRERQSSHDRLCGQEDELSYFKEVPVQVARGMMPSSLVLTVLGLVVAALGVRCWQKEPQHALAGASGLVLLLSGLLSLVPASWYTHELEVLPAPSGATLAVGYSLVLSYLGSCLEILGGVALTLSFHHCCKERRASKTTPSPVLEPGPRSVTGAYSNPWDVLEDERDGRHGRSTLPCDSDL", "length": 233, "header": "tr|A0A1D5PZV7-1|A0A1D5PZV7_CHICK Isoform 1 of Claudin 23 OS=Gallus gallus OX=9031 GN=CLDN23 PE=3 SV=2 CANONICAL=A0A1D5PZV7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7/entry", "sequence": { "sequence": "MRTPAVMIVGLVLCPCGLLLTLTGTLAPNWRQVSLIPEQPSDLILEQGIWDLCRERQSSHDRLCGQEDELSYFKEVPVQVARGMMPSSLVLTVLGLVVAALGVRCWQKEPQHALAGASGLVLLLSGLLSLVPASWYTHELEVLPAPSGATLAVGYSLVLSYLGSCLEILGGVALTLSFHHCCKERRASKTTPSPVLEPGPRSVTGAYSNPWDVLEDERDGRHGRSTLPCDSDL", "length": 233, "header": "tr|A0A1D5PZV7-1|A0A1D5PZV7_CHICK Isoform 1 of Claudin 23 OS=Gallus gallus OX=9031 GN=CLDN23 PE=3 SV=2 CANONICAL=A0A1D5PZV7-1" }, "locus": { "chromosome": "4", "start_pos": 49087229, "end_pos": 49086531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010453.1", "url": "https://www.ensembl.org/id/ENSGALT00010010453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006092.1", "url": "https://www.ensembl.org/id/ENSGALP00010006092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428756", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A288CFV8-1", "protein_name": "Claudin 23", "gene_name": "CLDN23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTPVVMTLGMVLAPCGLLLTLTSTLTPGWRLVKGFLDQPVDVVLYQGLWDMCREQSSRERQCGQPDELGYFAAEPVKVARGLMVTSLAVTALGLLLATLGVRCWQDEPHFALAGLSGVVLFAAGLLSLIPVSWYNHFLADRAVLPAQSSPVTVQVGYSLVLGYLGSCLLLLGGFSLALSFAPWCAERCRSCRKASPSSARRSSISTVHVDWLTPAIKYYSDGQHRPGPAQLGPTSRRKAGFPMPRPPPKAYSNQVDVLDGEKSPDSHLDGSSRSTRPCGSALPCDSDL", "length": 289 }, "evidence": [ { "id": "A0A1D5PZV7", "url": "https://omabrowser.org/oma/group/A0A1D5PZV7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MGT6-1", "protein_name": "Claudin 23", "gene_name": "CLDN23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRTPVVMTLGMVLAPCGLLLTLTSTLTPGWRLVKGFLDQPLDLVLYQGLWDMCREQSSRERQCGQPDDLGYFAAEPVRVARGLMVTSLAVTGLGLLLATLGVRCWRDEPHFVLAGLSGVVLFTAGLLSLIPVSWYNHFLADRTVLPAQPSPVTVQVGYSLVLGYLGSCLLLLGGFSLALSFAPWCAERCDSCRKAPSSSARRSSISTVYIDGPEPALTPAIKYYSDGQHRPRPDQLGATSQRKAGFPMPRPPPKAYSNPVDVLEGENATNSEPGSSSRSTRPCGSTLPCDSDV", "length": 293 }, "evidence": [ { "id": "A0A1D5PZV7", "url": "https://omabrowser.org/oma/group/A0A1D5PZV7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96B33-1", "protein_name": "Claudin-23", "gene_name": "CLDN23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPKPKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL", "length": 292 }, "evidence": [ { "id": "A0A1D5PZV7", "url": "https://omabrowser.org/oma/group/A0A1D5PZV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7D7-1", "protein_name": "Claudin-23", "gene_name": "Cldn23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRTPVVMTLGMVLTPCGLLLNLVSTLAPGWRLVKGFLDQPVDVVLYQGLWDICREQSSRERECGQPDEWNYFQTQPVQVARGLMITSLATTALGLLLASLGVRCWQDEPHYGLAGLSGVVFFVAGLFSLIPVSWYNHFLSDPDVLAAPSSPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCEERCRRCRKAPPAGPRRSSISTVYVDWPEPALTPAIKYYSDGQHRPPPTAEHRDTSKLKVGFPMPRPPPKSYTNPMDVLEGEEKKTATSQGGSSSRSTRPCQNSLPCDSDL", "length": 296 }, "evidence": [ { "id": "A0A1D5PZV7", "url": "https://omabrowser.org/oma/group/A0A1D5PZV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 233, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZV7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1D5PZX0-1", "uniprot_ac": "A0A1D5PZX0", "uniprot_id": "A0A1D5PZX0_CHICK", "mass": { "chemical_mass": 18865.0, "monoisotopic_mass": 18865.0 }, "refseq": { "ac": "XP_015138892", "name": "male-enhanced antigen 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138892" }, "gene_names": [ { "name": "MEA1", "type": "recommended", "evidence": [ { "id": "A0A1D5PZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0" } ] }, { "name": "MEA1", "type": "synonym", "evidence": [ { "id": "XP_015138892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138892" } ] } ], "protein_names": [ { "name": "Male-enhanced antigen 1", "type": "recommended", "evidence": [ { "id": "A0A1D5PZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0/entry#names_and_taxonomy" } ] }, { "name": "male-enhanced antigen 1", "type": "synonym", "evidence": [ { "id": "XP_015138892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138892" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138892" } ] }, { "annotation": "May play an important role in spermatogenesis and/or testis development.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0#function" }, { "database": "UniProtKB", "id": "ARBA00002540", "url": "https://www.uniprot.org/uniprotkb/ARBA00002540#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEA1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0", "locus": { "chromosome": "3", "start_pos": 4453037, "end_pos": 4454154, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018440", "url": "https://www.ensembl.org/id/ENSGALG00010018440" } ] } } ], "crossref": [ { "id": "A0A1D5PZX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033894", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033894", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107052849", "url": "https://www.ncbi.nlm.nih.gov/gene/107052849", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052849", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052849", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SIPMDPD", "url": "https://omabrowser.org/oma/group/SIPMDPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZX0", "url": "https://www.orthodb.org/?gene=A0A1D5PZX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZX0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVARRMGPERVCPEEPGPPEAPEGAAGWSGDEEDEEEEEEEEEEEEEGGGGYLYQPLSQEPEQGPAETGPPAGGAEPGPGLQERLQMLRLHLPEPPADSEDEEEEGAAAQSSRGSIPMDPEHVELVKRTMAGVKLPTLGIPAWASQISDEQWQAVVQRALQARHGAGSSRPEWK", "length": 175, "header": "tr|A0A1D5PZX0-1|A0A1D5PZX0_CHICK Isoform 1 of Male-enhanced antigen 1 OS=Gallus gallus OX=9031 GN=MEA1 PE=4 SV=2 CANONICAL=A0A1D5PZX0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX0/entry", "sequence": { "sequence": "MAVARRMGPERVCPEEPGPPEAPEGAAGWSGDEEDEEEEEEEEEEEEEGGGGYLYQPLSQEPEQGPAETGPPAGGAEPGPGLQERLQMLRLHLPEPPADSEDEEEEGAAAQSSRGSIPMDPEHVELVKRTMAGVKLPTLGIPAWASQISDEQWQAVVQRALQARHGAGSSRPEWK", "length": 175, "header": "tr|A0A1D5PZX0-1|A0A1D5PZX0_CHICK Isoform 1 of Male-enhanced antigen 1 OS=Gallus gallus OX=9031 GN=MEA1 PE=4 SV=2 CANONICAL=A0A1D5PZX0-1" }, "locus": { "chromosome": "3", "start_pos": 4454137, "end_pos": 4453462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044564.1", "url": "https://www.ensembl.org/id/ENSGALT00010044564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026525.1", "url": "https://www.ensembl.org/id/ENSGALP00010026525.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107052849", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052849", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q16626-1", "protein_name": "Male-enhanced antigen 1", "gene_name": "MEA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPERHLSGAPARMATVVLGGDTMGPERIFPNQTEELGHQGPSEGTGDWSSEEPEEEQEETGSGPAGYSYQPLNQDPEQEEVELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGATALNNHSSIPMDPEHVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQASPAWK", "length": 185 }, "evidence": [ { "id": "A0A1D5PZX0", "url": "https://omabrowser.org/oma/group/A0A1D5PZX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q29407-1", "protein_name": "Male-enhanced antigen 1", "gene_name": "MEA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVVLGGDTMGPERIFPNQTEELGPHQGPTEGTGDWSSEEPEEEQEETGAGPAGYSYQPLNQDPEQEEVELAPVGDGEDVVADIQDRIQALGLHLPDPPVESEDEDEQGATALNNHSSIPMDPEHVELVKRTMAGISLPAPGVPAWARELSDAQWEDVVQKALQARQAAPAWK", "length": 174 }, "evidence": [ { "id": "A0A1D5PZX0", "url": "https://omabrowser.org/oma/group/A0A1D5PZX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FVH7-1", "protein_name": "Male-enhanced antigen 1", "gene_name": "Mea1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVVLGGDTMGPERIFPNQTEDLGPHQGPTEGTGDWSSEEPEEEQEETGAGPAGYSYQPLNQDPEQEEVELAPVGEGEDGAADIQDRIQALGLHLPDPPLESEDEDEEGAAALSSHSSIPMDPEHVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQASPAWK", "length": 174 }, "evidence": [ { "id": "A0A1D5PZX0", "url": 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This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642903" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MOB3A", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9", "locus": { "chromosome": "28", "start_pos": 2554763, "end_pos": 2550702, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027901", "url": "https://www.ensembl.org/id/ENSGALG00010027901" } ] } } ], "crossref": [ { "id": "A0A1D5PZY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZY9", "database": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI63", "url": "https://www.orthodb.org/?gene=A0A8V1AI63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI63", "url": 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"MSHALKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLKVAVQLPPGEEQNDWVAVHVVDFFNRINLIYGTISDYCTEQSCPVMSGGPRYEYRWQDEHKYRKPTALSAPQYMNLLMDWIEVQINNEDIFPTNVGTPFPRNFLPVVKKILSRLFRVFVHVYIHHFDRITQMGSEAHVNTCYKHFYYFVKEFNLIDTKELEPRR", "length": 208, "header": "tr|A0A8V1AI63-1|A0A1D5PZY9_CHICK Computationally mapped isoform of MOB kinase activator 3A OS=Gallus gallus OX=9031 GN=MOB3A PE=4 SV=1 CANONICAL=A0A1D5PZY9-1" }, "locus": { "chromosome": "28", "start_pos": 2554390, "end_pos": 2552206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067636.1", "url": "https://www.ensembl.org/id/ENSGALT00010067636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041379.1", "url": "https://www.ensembl.org/id/ENSGALP00010041379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857182", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857182", "resource": "KEGG Pathway" } 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"uniprot_canonical_ac": "Q96BX8-1", "protein_name": "MOB kinase activator 3A", "gene_name": "MOB3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH", "length": 217 }, "evidence": [ { "id": "A0A1D5PZY9", "url": "https://omabrowser.org/oma/group/A0A1D5PZY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZY9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PZY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 216, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PZY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1D5PZY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A1D5PZY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZY9" }, { "id": "PIRSR605301-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605301-1" } ], "binding_site_uniprot": 164, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": 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"glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RIT3-1", "uniprot_ac": "A0A1L1RIT3", "uniprot_id": "A0A1L1RIT3_CHICK", "mass": { "chemical_mass": 49391.0, "monoisotopic_mass": 49391.0 }, "refseq": {}, "gene_names": [ { "name": "BSDC1", "type": "recommended", "evidence": [ { "id": "A0A1L1RIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3" } ] } ], "protein_names": [ { "name": "BSD domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A1L1RIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RIT3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BSDC1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3", "locus": { "chromosome": "23", "start_pos": 5557453, "end_pos": 5563868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017578", "url": "https://www.ensembl.org/id/ENSGALG00010017578" } ] } } ], "crossref": [ { "id": "A0A1L1RIT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RIT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003405", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003405", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419658", "url": "https://www.ncbi.nlm.nih.gov/gene/419658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCFLCWF", "url": "https://omabrowser.org/oma/group/TCFLCWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RIT3", "url": "https://www.orthodb.org/?gene=A0A1L1RIT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RIT3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RIT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGEDAGWWRSWLQQSYQAVKEKSTEALEFMKRDLAEFTQVVQHDTACTIAATASVVKDRLARTEASGATEKVRKGISDFLGVISDTFAPSPDKTIDCDVITLMATPTGTTEPYDSAKARLYSLQSDPATYCNEPDGPAELLEAWLSRFSLEEKKGEIAELLATSPSIRALYTKMVPAAVSHSEFWQRYFYKVHRLEQDEVRREALKQRAEQSIHQEEPGWEEDEEEFLGMSPLPCANVKFPQAAEKASASAALEGSQPSVHKGPSGESWAILPPELAPAEGSPSESSESVSLVTQIANPASVPVVQLQTGVQPSGNRDLSQRLLEATSEEQSPLPKPPEPGHPSAAAQEPAVCSEQTAVTGPKEVESKAQGRTETLKEEGPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQLALSKVEVSGELEDEEWEDWE", "length": 451, "header": "tr|A0A1L1RIT3-1|A0A1L1RIT3_CHICK Isoform 1 of BSD domain containing 1 OS=Gallus gallus OX=9031 GN=BSDC1 PE=1 SV=1 CANONICAL=A0A1L1RIT3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RIT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3/entry", "sequence": { "sequence": "MAEGEDAGWWRSWLQQSYQAVKEKSTEALEFMKRDLAEFTQVVQHDTACTIAATASVVKDRLARTEASGATEKVRKGISDFLGVISDTFAPSPDKTIDCDVITLMATPTGTTEPYDSAKARLYSLQSDPATYCNEPDGPAELLEAWLSRFSLEEKKGEIAELLATSPSIRALYTKMVPAAVSHSEFWQRYFYKVHRLEQDEVRREALKQRAEQSIHQEEPGWEEDEEEFLGMSPLPCANVKFPQAAEKASASAALEGSQPSVHKGPSGESWAILPPELAPAEGSPSESSESVSLVTQIANPASVPVVQLQTGVQPSGNRDLSQRLLEATSEEQSPLPKPPEPGHPSAAAQEPAVCSEQTAVTGPKEVESKAQGRTETLKEEGPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQLALSKVEVSGELEDEEWEDWE", "length": 451, "header": "tr|A0A1L1RIT3-1|A0A1L1RIT3_CHICK Isoform 1 of BSD domain containing 1 OS=Gallus gallus OX=9031 GN=BSDC1 PE=1 SV=1 CANONICAL=A0A1L1RIT3-1" }, "locus": { "chromosome": "23", "start_pos": 5563848, "end_pos": 5559227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042502.1", "url": "https://www.ensembl.org/id/ENSGALT00010042502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024993.1", "url": "https://www.ensembl.org/id/ENSGALP00010024993.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AS17-1", "protein_name": "BSD domain containing 1", "gene_name": "Bsdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGITVLDGRGREDVGWWRSWLQQSYQAVKEKSTEALEFMKRDLTEFTQVVQHDTACTIAATASVVKERLATEGSSGATEKVKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSRFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRADQSISEEPGWEEEEEELERIVPSPKEAKLPQETKTSTAPENEPAPQSPCEEIPVEAPAEATPSESSESISLATQIANPAAAPQPPELPKDLSQKLLEASLEEQSLAEDAGETGPPPPVTSKPLTPAGRASGLEPRPPARVETLREEVPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVEASGELEDVEWEDWE", "length": 434 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2BIJ3-1", "protein_name": "BSD domain-containing protein 1", "gene_name": "bsdc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADGEGGWWGGWLTQSFQSVKDKSAEAYEFIKRDLTEFSSVVQHDTACSVVATANAIKSKLAVEGSSETTEKVKKGITNILGVITDTLAPPPDKTIDCDVITLVATPTGTTEVYDSGKARLYSLQADPATYCNEPDGPPQQFDSWLSTFSLEERKAEISELLVSSPAIRALYTKMVPAAVAHAEFWQRYFYKVFQLEQEEARRVALKQRAEQTDHSESLGWEEEDEEGEFLGATSLSRLDFTPPVEESRVPAVTVADTPESSSPPQAVASLSNVASDVTPSVSSDSVSFPTQIENQAESVTIRVTQPSPAADELSQKLSDTGLQETFPEERPAPREETAREDMAQDLRVFELNSDSGKSTPSNNGKKGSSTDVSEDWEKDFDLDMTEEEVQMALSKVDATEELEDEDWENWE", "length": 412 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3H940-1", "protein_name": "BSD domain-containing protein 1 isoform X1", "gene_name": "Bsdc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEGEDVGWWRSWLQQSYQAVKEKSTEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRADQSISEEPRWEEEEEELEGIAPSPKDVKIPKETKTSTSPEDGPGPQSPCEDTPVEPPAEVTPSESSESISLMTQIANPATAPEAPVLPKDLSQKLLEASLEEQSLAEDEGETGPPPPVPSKPLTPAGRASGPDPRPPARVETLREEVPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASDELEDAEWEDWE", "length": 427 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SX22-1", "protein_name": "BSD domain-containing protein 1", "gene_name": "BSDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPGGDGAEDDVGAGIGPPAPGWCLRGRCRVGSQREDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQRDTACTIAATASVVKEKLTTEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELAGVSPTSLKEAKVPVARPSTSPEGGPGPQSPCEENLVTPVEPPTEVTPSESSESVSLVTQIAKPPPASEAPALPKDLSQKLLEASLEEQDLAVDTGETGPPPRAQSKPHTPACRPSGPEPRPPARVETLREEILTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWD", "length": 461 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80Y55-1", "protein_name": "BSD domain-containing protein 1", "gene_name": "Bsdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGEDVGWWRSWLQQSYQAVKEKSTEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATEGSSGATEKVKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSEFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRADQSISEEPGWEEEEEELEGIVPSPKEAKIPKETKTTTSPEDEPAPQSPCEETPVEPPAEATPSESSESISLVTQVANPAAAPEAPELPKDLSQKLFEASLEEQSLAEDEGETGPPPPPPSKPLTPAGRASGPEPRPPARVETLREEVPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE", "length": 427 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NW68-1", "protein_name": "BSD domain-containing protein 1", "gene_name": "BSDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE", "length": 430 }, "evidence": [ { "id": "A0A1L1RIT3", "url": "https://omabrowser.org/oma/group/A0A1L1RIT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RIT3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RIT3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RIT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 451, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RIT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RIT3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RIW4-1", "uniprot_ac": "A0A1L1RIW4", "uniprot_id": "A0A1L1RIW4_CHICK", "mass": { "chemical_mass": 28046.0, "monoisotopic_mass": 28046.0 }, "refseq": {}, "gene_names": [ { "name": "PLPP5", "type": "recommended", "evidence": [ { "id": "A0A1L1RIW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4" } ] } ], "protein_names": [ { "name": "Phospholipid phosphatase 5", "type": "synonym", "evidence": [ { "id": "A0A1L1RIW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RIW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLPP5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4", "locus": { "chromosome": "22", "start_pos": 2456738, "end_pos": 2459494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017825", "url": "https://www.ensembl.org/id/ENSGALG00010017825" } ] } } ], "crossref": [ { "id": "A0A1L1RIW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RIW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000044574", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044574", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RIW4", "url": "https://www.orthodb.org/?gene=A0A1L1RIW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3A7", "url": "https://www.orthodb.org/?gene=A0A8V0Z3A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029485", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029485", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RIW4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RIW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAVRSLRRAMELLPPFQRVVQPEEMWLYRNPYVEADRVPTAPMFFIAFLSPVLLIILARLFLGADHEDTREASLAASLALVLNGVFTNTLKLVVGRPRPDFFYRCFPDGRVNAELTCTGDPGVVAEGRKSFPSGHSSFAFAGLAFCAFYLAGKLHCFAPGRRGSALQLCAFLLPLFIATLIAVSRTCDYKHHWQDVLVGSAMGFVLAYLCYRQYYPPLMDSVCHKPFLSISKQLPAHQEKPAASSFHLDI", "length": 252, "header": "tr|A0A1L1RIW4-1|A0A1L1RIW4_CHICK Isoform 1 of Phospholipid phosphatase 5 OS=Gallus gallus OX=9031 GN=PLPP5 PE=3 SV=2 CANONICAL=A0A1L1RIW4-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RIW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIW4/entry", "sequence": { "sequence": "MPAAVRSLRRAMELLPPFQRVVQPEEMWLYRNPYVEADRVPTAPMFFIAFLSPVLLIILARLFLGADHEDTREASLAASLALVLNGVFTNTLKLVVGRPRPDFFYRCFPDGRVNAELTCTGDPGVVAEGRKSFPSGHSSFAFAGLAFCAFYLAGKLHCFAPGRRGSALQLCAFLLPLFIATLIAVSRTCDYKHHWQDVLVGSAMGFVLAYLCYRQYYPPLMDSVCHKPFLSISKQLPAHQEKPAASSFHLDI", "length": 252, "header": "tr|A0A1L1RIW4-1|A0A1L1RIW4_CHICK Isoform 1 of Phospholipid phosphatase 5 OS=Gallus gallus OX=9031 GN=PLPP5 PE=3 SV=2 CANONICAL=A0A1L1RIW4-1" }, "locus": { "chromosome": "22", "start_pos": 2459362, "end_pos": 2457322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043092.1", "url": "https://www.ensembl.org/id/ENSGALT00010043092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025582.1", "url": "https://www.ensembl.org/id/ENSGALP00010025582.1" } ] } }, { "isoform_ac": "A0A8V0Z3A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A7/entry", "sequence": { "sequence": "VPTPCCVQGRQPADQAAQGHIQPGLECLQGWGIHSLLGQAALTIRFIAFLSPVLLIILARLFLGADHEDTREASLAASLALVLNGVFTNTLKLVVGRPRPDFFYRCFPDGRVNAELTCTGDPGVVAEGRKSFPSGHSSFAFAGLAFCAFYLAGKLHCFAPGRRGSALQLCAFLLPLFIATLIAVSRTCDYKHHWQDVLVGSAMGFVLAYLCYRQYYPPLMDSVCHKPFLSISKQLPAHQEKPAASSFHLDI", "length": 251, "header": "tr|A0A8V0Z3A7-1|A0A8V0Z3A7_CHICK Computationally mapped isoform of Phospholipid phosphatase 5 OS=Gallus gallus OX=9031 GN=PLPP5 PE=3 SV=1 CANONICAL=A0A1L1RIW4-1" }, "locus": { "chromosome": "22", "start_pos": 2459011, "end_pos": 2457322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043085.1", "url": "https://www.ensembl.org/id/ENSGALT00010043085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025575.1", "url": "https://www.ensembl.org/id/ENSGALP00010025575.1" } ] } }, { "isoform_ac": "A0A8V0Z3B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B6/entry", "sequence": { "sequence": "MELLPPFQRVVQPEEMWLYRNPYVEADRVPTAPMFFIAFLSPVLLIILARLFLGADHEDTREASLAASLALVLNGVFTNTLKLVVGRPRPDFFYRCFPDGRVNAELTCTGDPGVVAEGRKSFPSGHSSFAFAGLAFCAFYLAGKLHCFAPGRRGSALQLCAFLLPLFIATLIAVSRTCDYKHHWQDVLVGSAMGFVLAYLCYRQYYPPLMDSVCHKPFLSISKQLPAHQEKPAASSFHLDI", "length": 241, "header": "tr|A0A8V0Z3B6-1|A0A8V0Z3B6_CHICK Computationally mapped isoform of Phospholipid phosphatase 5 OS=Gallus gallus OX=9031 GN=PLPP5 PE=3 SV=1 CANONICAL=A0A1L1RIW4-1" }, "locus": { "chromosome": "22", "start_pos": 2459329, "end_pos": 2457322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043096.1", "url": "https://www.ensembl.org/id/ENSGALT00010043096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025585.1", "url": "https://www.ensembl.org/id/ENSGALP00010025585.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2029485", "name": "", "url": 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"tr|A0A8V0Z9F1-1|A0A8V0Z9F1_CHICK Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 1 OS=Gallus gallus OX=9031 GN=CNIH1 PE=1 SV=1 CANONICAL=A0A1L1RJI1-1" }, "locus": { "chromosome": "5", "start_pos": 56069907, "end_pos": 56064817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045738.1", "url": "https://www.ensembl.org/id/ENSGALT00010045738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027263.1", "url": "https://www.ensembl.org/id/ENSGALP00010027263.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in 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This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144125" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RK18", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RK18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BORCS7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RK18", "locus": { "chromosome": "6", "start_pos": 24180773, "end_pos": 24177090, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018199", "url": "https://www.ensembl.org/id/ENSGALG00010018199" } ] } } ], "crossref": [ { "id": "A0A1L1RK18", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RK18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008124", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008124", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423869", "url": "https://www.ncbi.nlm.nih.gov/gene/423869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HAAKNFA", "url": "https://omabrowser.org/oma/group/HAAKNFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RK18", "url": "https://www.orthodb.org/?gene=A0A1L1RK18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4V6", "url": "https://www.orthodb.org/?gene=A0A8V0Z4V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31397", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31397", "database": 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[ { "database": "Ensembl Transcript", "id": "ENSGALT00010043983.1", "url": "https://www.ensembl.org/id/ENSGALT00010043983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026154.1", "url": "https://www.ensembl.org/id/ENSGALP00010026154.1" } ] } }, { "isoform_ac": "A0A8V0Z4V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4V6/entry", "sequence": { "sequence": "MAAGGAAEAQARFGHSVKGLLTEKVTSCGTDVIALTKQVLKGSRSAELLGQAARNMVMQEDAILHSEDSLRKMAIITTHLQYQILWRPPHAGLSAALPIAGHTLGLGS", "length": 108, "header": "tr|A0A8V0Z4V6-1|A0A8V0Z4V6_CHICK Computationally mapped isoform of BLOC-1-related complex subunit 7 OS=Gallus gallus OX=9031 GN=BORCS7 PE=3 SV=1 CANONICAL=A0A1L1RK18-1" }, "locus": { "chromosome": "6", "start_pos": 24178365, "end_pos": 24177702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043978.1", "url": "https://www.ensembl.org/id/ENSGALT00010043978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026151.1", "url": 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"id": "NP_001376584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376584" } ] }, { "name": "FMR1 neighbor", "type": "synonym", "evidence": [ { "id": "A0A1L1RKE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKE8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2286007.24890.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000071.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376584", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RKE8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FMR1NB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKE8", "locus": { "chromosome": "4", "start_pos": 18555383, "end_pos": 18570549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013923", "url": "https://www.ensembl.org/id/ENSGALG00010013923" } ] } } ], "crossref": [ { "id": "A0A1L1RKE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RKE8", "database": "AlphaFoldDB", 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RL16-1", "uniprot_ac": "A0A1L1RL16", "uniprot_id": "A0A1L1RL16_CHICK", "mass": { "chemical_mass": 48981.0, "monoisotopic_mass": 48981.0 }, "refseq": {}, "gene_names": [ { "name": "GPR19", "type": "recommended", "evidence": [ { "id": "A0A1L1RL16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 19", "type": "recommended", "evidence": [ { "id": "A0A1L1RL16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain. May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence. Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RL16", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16#function" }, { "database": "UniProtKB", "id": "ARBA00093282", "url": "https://www.uniprot.org/uniprotkb/ARBA00093282#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RL16", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR19", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16", "locus": { "chromosome": "1", "start_pos": 72063975, "end_pos": 72072470, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021891", "url": "https://www.ensembl.org/id/ENSGALG00010021891" } ] } } ], "crossref": [ { "id": "A0A1L1RL16", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RL16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000045619", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000045619", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857902", "url": "https://www.ncbi.nlm.nih.gov/gene/100857902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RL16", "url": "https://www.orthodb.org/?gene=A0A1L1RL16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RL16", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RL16-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWNRAQAGDMTVMLDHSTDNNASFVLPTLLLLLQNKSYPKTSLPAADHEMTESPQEPRPSRNRTVLQYELKPGEIVSASMVFGVLWLISIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVGSAPFVLLQLTSGRWTLGSVMCKLVRYIQYFTPGVQIYVLLSICMDRFYTIVYPLSFKVSREKAKKMIVAAWIFDLAFMSPVFFFYGSSEEDHCNFFLPNSWEGAIYSIIHLLVVFFTPSILIILFYQKVVKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLMLNLVFLLSWLPFYVVQLWHPQETDYRESSLVFMAITWISFSSSASKPTLYSVYNANFRRGMKETFCMSTMKCYRSNAYTITTSSRIAKKNYVGISEIPAPAKTVTKDSIYYSFNREAKEKKLAWPIHSNPPNTFV", "length": 426, "header": "tr|A0A1L1RL16-1|A0A1L1RL16_CHICK Isoform 1 of Probable G-protein coupled receptor 19 OS=Gallus gallus OX=9031 GN=GPR19 PE=4 SV=2 CANONICAL=A0A1L1RL16-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RL16-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL16/entry", "sequence": { "sequence": "MLWNRAQAGDMTVMLDHSTDNNASFVLPTLLLLLQNKSYPKTSLPAADHEMTESPQEPRPSRNRTVLQYELKPGEIVSASMVFGVLWLISIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVGSAPFVLLQLTSGRWTLGSVMCKLVRYIQYFTPGVQIYVLLSICMDRFYTIVYPLSFKVSREKAKKMIVAAWIFDLAFMSPVFFFYGSSEEDHCNFFLPNSWEGAIYSIIHLLVVFFTPSILIILFYQKVVKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLMLNLVFLLSWLPFYVVQLWHPQETDYRESSLVFMAITWISFSSSASKPTLYSVYNANFRRGMKETFCMSTMKCYRSNAYTITTSSRIAKKNYVGISEIPAPAKTVTKDSIYYSFNREAKEKKLAWPIHSNPPNTFV", "length": 426, "header": "tr|A0A1L1RL16-1|A0A1L1RL16_CHICK Isoform 1 of Probable G-protein coupled receptor 19 OS=Gallus gallus OX=9031 GN=GPR19 PE=4 SV=2 CANONICAL=A0A1L1RL16-1" }, "locus": { "chromosome": "1", "start_pos": 72072025, "end_pos": 72064328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053240.1", "url": "https://www.ensembl.org/id/ENSGALT00010053240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032086.1", "url": "https://www.ensembl.org/id/ENSGALP00010032086.1" } ] } } ], "glycosylation": [], 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512502" } ] } ], "protein_names": [ { "name": "Transmembrane protein 267", "type": "recommended", "evidence": [ { "id": "A0A1L1RL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL63/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 267 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040512502", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512502" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512502" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RL63", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM267", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL63", "locus": { "chromosome": "Z", "start_pos": 14229659, "end_pos": 14241981, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014427", "url": "https://www.ensembl.org/id/ENSGALG00010014427" } ] } } ], "crossref": [ { "id": "A0A1L1RL63", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RL63", "database": 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"url": "https://omabrowser.org/oma/group/A0A1L1RL63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZK9-1", "protein_name": "Transmembrane protein 267", "gene_name": "Dmel\\CG10866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPHCHTMVYMRIVLTTLVTITCLLGDNFVELTQHPLLKALADNATHAAIGALTGITFATQFYERTSQLFGWILIFTCFVVSSFIDLDHFVEARSLYLEDATNLSKRPFLHCSSIIVVMLLFYMCTACLNYFRTSLMLGSLLCAFITHHTRDAVRRGYWLCPLGHTDRMPQLAYILTTILTPHLLGCLHNVCRSATVLNFLGQYVKLSEGQYRSGSTANYRYMQV", "length": 224 }, "evidence": [ { "id": "A0A1L1RL63", "url": "https://omabrowser.org/oma/group/A0A1L1RL63/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RL63", "url": 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This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421458" } ] }, { "annotation": "Substrate-recognition component of a Cul5-RING (CRL5) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. 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} ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RN40", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RN40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RN40", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RN40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "id": "GO:0140627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140627", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RN40", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RN40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642579.3. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSHGMAHPAAPFSADGDSAAVIPRKQPRLQLPFQQEEQKTLRSYENIESKARKILSTSNQKMTHLFLLKDLPVHLTYLRDRFTTLDSRPALEPLYIGLFGSSGAGKSTLLNTILGKRFFLPVSGTRTCTSCQVHVSVCRSKHYEAKIFLLSDEEWKEEVRNLVMLLENRHENSETDGDLEHAIKVLKNIYGEGADEKSYEDLMRTKPVITIPPSRVITLRKTEAEDLSNELDPYIRNQDGLEGVGVVDNSQCSEQTRLWPLIKQVQVTLPSSDLVPEGVIFVDIPGTGDANKKRDEMWKESILQCTSIWIVADVERVSGAKAHEIMVQEAIKACQVGKCSDITFVITKMDKINEDEYLRSHPGTSRDVSKRDAILGMKQDLKARKSRTLRERMKRNLPSDAEVLQKQELVFPVSAQEYWNPTVLRREDTEIVELRAHIRKLYLDTKRSQLQDYMKEILVVFSLVDVYHSTQLSPNPSVKKDELDRFMSEKIQTLKNSIEVTFGHIDTPLMTGVRSARSKYKKNIEKVFMQGRTSSGFHRTLKAVCVRKGVYVSRVFSRIDINNCLAEPIYAEIGVMFANIFRKQALTRASLQTSINVFSKEVKDKFMDFGKVMNLSTSKLSFLEQETDIIMRAIDREILLKKKAIYESLELTIQSILSPCYEEAANIRGRDASVRIKATLENNIDLEVQRAMFERAKEKMMSQFQDLTEQITTKLSRDFLSMLGITFCHNDQLMGVLPDLREECQEIQNLLETLRQLE", "length": 760, "header": "tr|A0A1L1RPC1-1|A0A1L1RPC1_CHICK Isoform 1 of Nuclear GTPase, germinal center associated OS=Gallus gallus OX=9031 GN=NUGGC PE=1 SV=2 CANONICAL=A0A1L1RPC1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RPC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPC1/entry", "sequence": { "sequence": "MEGSHGMAHPAAPFSADGDSAAVIPRKQPRLQLPFQQEEQKTLRSYENIESKARKILSTSNQKMTHLFLLKDLPVHLTYLRDRFTTLDSRPALEPLYIGLFGSSGAGKSTLLNTILGKRFFLPVSGTRTCTSCQVHVSVCRSKHYEAKIFLLSDEEWKEEVRNLVMLLENRHENSETDGDLEHAIKVLKNIYGEGADEKSYEDLMRTKPVITIPPSRVITLRKTEAEDLSNELDPYIRNQDGLEGVGVVDNSQCSEQTRLWPLIKQVQVTLPSSDLVPEGVIFVDIPGTGDANKKRDEMWKESILQCTSIWIVADVERVSGAKAHEIMVQEAIKACQVGKCSDITFVITKMDKINEDEYLRSHPGTSRDVSKRDAILGMKQDLKARKSRTLRERMKRNLPSDAEVLQKQELVFPVSAQEYWNPTVLRREDTEIVELRAHIRKLYLDTKRSQLQDYMKEILVVFSLVDVYHSTQLSPNPSVKKDELDRFMSEKIQTLKNSIEVTFGHIDTPLMTGVRSARSKYKKNIEKVFMQGRTSSGFHRTLKAVCVRKGVYVSRVFSRIDINNCLAEPIYAEIGVMFANIFRKQALTRASLQTSINVFSKEVKDKFMDFGKVMNLSTSKLSFLEQETDIIMRAIDREILLKKKAIYESLELTIQSILSPCYEEAANIRGRDASVRIKATLENNIDLEVQRAMFERAKEKMMSQFQDLTEQITTKLSRDFLSMLGITFCHNDQLMGVLPDLREECQEIQNLLETLRQLE", "length": 760, "header": "tr|A0A1L1RPC1-1|A0A1L1RPC1_CHICK Isoform 1 of Nuclear GTPase, germinal center associated OS=Gallus gallus OX=9031 GN=NUGGC PE=1 SV=2 CANONICAL=A0A1L1RPC1-1" }, "locus": { "chromosome": "3", "start_pos": 104929391, "end_pos": 104919347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024179.1", "url": "https://www.ensembl.org/id/ENSGALT00010024179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013769.1", "url": "https://www.ensembl.org/id/ENSGALP00010013769.1" } ] } }, { "isoform_ac": "A0A8V0Y5X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X0/entry", "sequence": { "sequence": "MEGSHGMAHPAAPFSADGDSAAVIPRKQPRLQLPFQQEEQKTLRSYENIESKARKILSTSNQKMTHLFLLKDLPVHLTYLRDRFTTLDSRPALEPLYIGLFGSSGAGKSTLLNTILGKRFFLPVSGTRTCTSCQVHVSVCRSKHYEAKIFLLSDEEWKEEVRNLVMLLENRHENSETDGDLEHAIKVLKNIYGEGADEKSYEDLMRTKPVITIPPSRVITLRKTEAEDLSNELDPYIRNQDGLEGVGVVDNSQCSEQTRLWPLIKQVQVTLPSSDLVPEGVIFVDIPGTGDANKKRDEMWKESILQCTSIWIVADVERVSGAKAHEIMVQEAIKACQVGKCSDITFVITKMDKINEDEYLRSHPGTSRNLPSDAEVLQKQELVFPVSAQEYWNPTVLRREDTEIVELRAHIRKLYLDTKRSQLQDYMKEILVVFSLVDVYHSTQLSPNPSVKKDELDRFMSEKIQTLKNSIEVTFGHIDTPLMTGVRSARSKYKKNIEKVFMQGRTSSGFHRTLKAVCVRKGVYVSRVFSRIDINNCLAEPIYAEIGVMFANIFRKQALTRASLQTSINVFSKEVKDKFMDFGKVMNLSTSKLSFLEQETDIIMRAIDREILLKKKAIYESLELTIQSILSPCYEEAANIRGRDASVRIKATLENNIDLEVQRAMFERAKEKMMSQFQDLTEQITTKLSRDFLSMLGITFCHNDQLMGVLPDLREECQEIQNLLETLRQLE", "length": 731, "header": "tr|A0A8V0Y5X0-1|A0A1L1RPC1_CHICK Computationally mapped isoform of Nuclear GTPase, germinal center associated OS=Gallus gallus OX=9031 GN=NUGGC PE=1 SV=1 CANONICAL=A0A1L1RPC1-1" }, "locus": { "chromosome": "3", "start_pos": 104929391, "end_pos": 104919347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024185.1", "url": "https://www.ensembl.org/id/ENSGALT00010024185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013772.1", "url": "https://www.ensembl.org/id/ENSGALP00010013772.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422002", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422002", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TCH5-1", "protein_name": "Nuclear GTPase, germinal center associated, tandem duplicate 3 isoform X1", "gene_name": "nuggc.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASHTINFITWNVNGLKQNRDQKFQELQNADIVFLQETHIGVRDKQIEDYKKDWVVFYTKYTSSSRGTAILVRKSLDFECISHDKDNRGAYVVLKCKLAGQKYTLVSVYNHHTDAKTLDNLSRYLQKMTTGLLVIGGDFNTILNPFIDKKNNSNKIANKRNQKNLHLFVDKFMKSLQLADVWRRMNPVKQDFTFYIRDRPVSRLDYFFIPDECMWRVRSCEIMNSRSGELKDHQPVSLEINCVYTEPLLIDQTQLHFKIFNSKKLLLTDETSSLQCEESSSAVSEVDIVSAVQSLQVSDTVRPDDIPVSFYKDNIRDVIPYIKMLYDGIHMGEVNCSELYFQDPQDDIPHFFNADYLIIATILARRLDDFLKSQSKGTIKDTAIVMITPKTVCTEAMLCCLKDEIEDSHSVLYQDFLIVQNLLRDSKSLECVGCPLKPVLTALKLKSCALKLCKNLENYAVHVFKTNVIICIPSEDLDKMHAMESSNNEEEYDIMTLFRGQSVEGNESASEDYDGLSDDTEENCLGYSNTLFEDSVGSIEHEGKSKSIESDGRTTMYAVVTLEESEEVMVTASNWLSEDKKQCYWPPYKSSEKFIEAVQKGLAPQTGEKSWEKLAVLFHEEYGTYEEAKEKQKELNEQTEQAATAVNQVTETCPLFPGPSLGFSQNASGSKVFSIAVLAGTTLEIQGTKRKRESRDLNISAKSNSEMAILNMAKKKMNEVNVRLQNISSTDRTTNELKNTILDAIAKINEMEKDKRRKETIGVFGKTGEGKSSLLNAVLGLEGLLPSGSLGACTAVITQVEANLEDSEYKAEIELISKEEWEREIASKDERTDTDNERIIAVYGADADKKSLEELKKDAKYAEIDHFLSAGKKIISHTEVFDFLHDVKRNIEQSEYNPGGWYWPLVKSVTIKIPDRQELLEHIVLFDVPGTGDCNKIRNDLWKSKVRECSSVWIVNGINRAISSIEPWSIMEHCMQDLGPGGQCKTINFICTRTDDINIKEYQRSARPSGDQFTSGKNLKTACIHHRNKTAKDSVKNKFETMKSKDFRRFTADVFTVSSKAYFDADLQMDQNETEIPKLQDLLKNTNKSIRRELTRDYVNQAKGVLFFIQSIKLDTNEGMAKLKATVCKDYYESLEKALKELNSQFNSHYKIIEQCFSKGVEKSVEQCVSTTKPVIASVKPSDKTLQALCKNKGYYWPKNKDAPVDLNKCLAKHIYENIDEEFNLIFPVDSKIKTGKSVQEQIDKFSIIQNGTVYAPSSMLYHIQNFMKTEETKVKTFLKSDVVQRKINIYSLIQTTIQDQMTAGYKKAAEKRGLGAMGKRETTIIETIELLKDSMFKDAKIQFLKEFKSVTNYIGKTLKTELSKSVERSFSQSSKASLMDVSTEIETLETLSEHIAEI", "length": 1399 }, "evidence": [ { "id": "A0A1L1RPC1", "url": "https://omabrowser.org/oma/group/A0A1L1RPC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPC1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RPC1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 760, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RPC1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RPC1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RPC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPC1" }, { "id": "PF00350", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynamin N-terminal", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 323, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 616, "end_pos": 618 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RPU6-1", "uniprot_ac": "A0A1L1RPU6", "uniprot_id": "A0A1L1RPU6_CHICK", "mass": { "chemical_mass": 33410.0, "monoisotopic_mass": 33410.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM53", "type": "recommended", "evidence": [ { "id": "A0A1L1RPU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6" } ] } ], "protein_names": [ { "name": "Transmembrane protein 53", "type": "synonym", "evidence": [ { "id": "A0A1L1RPU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPU6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM53", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6", "locus": { "chromosome": "8", "start_pos": 20421653, "end_pos": 20425156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025612", "url": "https://www.ensembl.org/id/ENSGALG00010025612" } ] } } ], "crossref": [ { "id": "A0A1L1RPU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RPU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010110", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RPU6", "url": "https://www.orthodb.org/?gene=A0A1L1RPU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12265:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12265:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RPU6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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protein 53 OS=Gallus gallus OX=9031 GN=TMEM53 PE=1 SV=2 CANONICAL=A0A1L1RPU6-1" }, "locus": { "chromosome": "8", "start_pos": 20424957, "end_pos": 20422226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062496.1", "url": "https://www.ensembl.org/id/ENSGALT00010062496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038645.1", "url": "https://www.ensembl.org/id/ENSGALP00010038645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of nucleocytoplasmic transport", "id": "GO:0046822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046822", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPU6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPU6" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026744" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719334.1, SRR12888509.22412.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992531, SAMEA103992544 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000043.1. On Aug 8, 2005 this sequence version replaced XP_426962.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026744", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026744" } ] }, { "annotation": "In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XI45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI45#function" }, { "database": "UniProtKB", "id": "ARBA00023764", "url": "https://www.uniprot.org/uniprotkb/ARBA00023764#function" }, { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0#function" }, { "database": "UniProtKB", "id": "Q9NVT9", "url": "https://www.uniprot.org/uniprotkb/Q9NVT9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARMC1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0", "locus": { "chromosome": "2", "start_pos": 114479602, "end_pos": 114509822, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003121", "url": "https://www.ensembl.org/id/ENSGALG00010003121" } ] } } ], "crossref": [ { "id": "Q5ZMQ0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036567", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "429406", "url": "https://www.ncbi.nlm.nih.gov/gene/429406", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429406", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429406", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNEMNSC", "url": "https://omabrowser.org/oma/group/VNEMNSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XI45", "url": "https://www.orthodb.org/?gene=A0A8V0XI45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMQ0", "url": "https://www.orthodb.org/?gene=Q5ZMQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46840:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46840:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMQ0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMQ0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026744", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XI45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMQ0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSTMSDEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFLDHPSPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEVYDILQSSNMSDMDNVNEMNYRRRKAQFFLGSTNKRAKTVVLHIDGLDDSSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALATAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTDLPEYLPEDESPSKEQDKAVSRVGSHPEGAASWLSTAANFLSRSFYW", "length": 279, "header": "sp|Q5ZMQ0-1|ARMC1_CHICK Isoform 1 of Armadillo repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=ARMC1 PE=2 SV=1 CANONICAL=Q5ZMQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XI45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI45/entry", "sequence": { "sequence": "MNSTMSDEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFLDHPSPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEVYDILQSSNMSDMDNVNEMNYRRRKAQFFLGSTNKRAKTVVLHIDGLDDSSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALATAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTDLPEYLPEDESPSKEQDKAQTFYLDLSTGELVFGVKRLCEPTGGPVFHWCGELPSAICNKLSQKF", "length": 297, "header": "tr|A0A8V0XI45-1|ARMC1_CHICK Computationally mapped isoform of Armadillo repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=ARMC1 PE=2 SV=1 CANONICAL=Q5ZMQ0-1" }, "locus": { "chromosome": "2", "start_pos": 114507760, "end_pos": 114481568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007281.1", "url": "https://www.ensembl.org/id/ENSGALT00010007281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004370.1", "url": "https://www.ensembl.org/id/ENSGALP00010004370.1" } ] } }, { "isoform_ac": "Q5ZMQ0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0/entry#Q5ZMQ0-1", "sequence": { "sequence": "MNSTMSDEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFLDHPSPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEVYDILQSSNMSDMDNVNEMNYRRRKAQFFLGSTNKRAKTVVLHIDGLDDSSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALATAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTDLPEYLPEDESPSKEQDKAVSRVGSHPEGAASWLSTAANFLSRSFYW", "length": 279, "header": "sp|Q5ZMQ0-1|ARMC1_CHICK Isoform 1 of Armadillo repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=ARMC1 PE=2 SV=1 CANONICAL=Q5ZMQ0-1" }, "locus": { "chromosome": "2", "start_pos": 114507760, "end_pos": 114481677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007284.1", "url": "https://www.ensembl.org/id/ENSGALT00010007284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004371.1", "url": "https://www.ensembl.org/id/ENSGALP00010004371.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:429406", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429406", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BN83-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "Armc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSSSSTVNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPSVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEINSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDAPVEVEENTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTB0-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "ARMC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSSSSTMNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZBE1-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "ARMC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSSSSTMNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKSTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55CP4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSALSMVQSLHKLAKDVDNREHIVKDQGCLAVLVMLLGSNEEDVEMVLLCLETLELLSHNQNNKQPMLKEPGLVSTLKKLQQKDQYKSIVDKVLINIEGSSDKGTINETTKIDTTTTTNTATATSYSTAPKKSASTSFSMLIGEKLPIKDTPVKSNNTASQVSSSKSIDPALIKTLLLHVKGMNNESTKKQLEECLLKTKGVISFMIDLSQCHATVRTSLSSDEIKLVIRNNVGLSASLIIDGQEEVESTPDYLPEPYNPNNSNSSKRWGWGSIISFGAQEQKQEGNWGWNSFSKVLFG", "length": 299 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D7A8-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "Armc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSSTMNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNLADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDAPVEVEENTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVT9-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "ARMC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "Q5ZMQ0", "url": "https://omabrowser.org/oma/group/Q5ZMQ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMQ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMQ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 279, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMQ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMQ0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"tr|A0A8V0XK61-1|HMGN3_CHICK Computationally mapped isoform of High mobility group nucleosome-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=HMGN3 PE=3 SV=1 CANONICAL=Q5ZIR5-1" }, "locus": { "chromosome": "3", "start_pos": 79185964, "end_pos": 79162712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008812.1", "url": "https://www.ensembl.org/id/ENSGALT00010008812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005156.1", "url": "https://www.ensembl.org/id/ENSGALP00010005156.1" } ] } }, { "isoform_ac": "Q5ZIR5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR5/entry#Q5ZIR5-1", "sequence": { "sequence": "MPKRKSPEGAEGKDAAKVTKQEPTRRSARLSAKPAPPKPEPKPRKTTKKEPGTKANKGAKGKKDEKQEAAKEGTTPSENGENKAEEAQKTESVGDKNE", "length": 98, "header": "sp|Q5ZIR5-1|HMGN3_CHICK Isoform 1 of High mobility group nucleosome-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=HMGN3 PE=3 SV=1 CANONICAL=Q5ZIR5-1" }, "locus": { "chromosome": "3", "start_pos": 79185989, "end_pos": 79162712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008814.1", "url": "https://www.ensembl.org/id/ENSGALT00010008814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005158.1", "url": "https://www.ensembl.org/id/ENSGALP00010005158.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIR5", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": 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"id": "Q5ZJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ] }, { "name": "SLC10A7", "type": "synonym", "evidence": [ { "id": "NP_001026302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302" } ] } ], "protein_names": [ { "name": "Sodium/bile acid cotransporter 7", "type": "recommended", "evidence": [ { "id": "Q5ZJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/bile acid cotransporter 7", "type": "synonym", "evidence": [ { "id": "NP_001026302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302" }, { "id": "Q5ZJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 10 member 7", "type": "synonym", "evidence": [ { "id": "Q5ZJH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8/entry#names_and_taxonomy" } ] }, { "name": "sodium/bile acid cotransporter 7", "type": "synonym", "evidence": [ { "id": "NP_001026302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302" } ] }, { "name": "solute carrier family 10 (sodium/bile acid cotransporter family), member 7", "type": "synonym", "evidence": [ { "id": "NP_001026302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720456.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Aug 8, 2005 this sequence version replaced XP_420432.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302" } ] }, { "annotation": "Does not show transport activity towards bile acids or steroid sulfates.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XLN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLN1#function" }, { "database": "UniProtKB", "id": "PIRNR026166", "url": "https://www.uniprot.org/uniprotkb/PIRNR026166#function" }, { "database": "UniProtKB", "id": "A0A8V0XSZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSZ8#function" }, { "database": "UniProtKB", "id": "E1BU54", "url": "https://www.uniprot.org/uniprotkb/E1BU54#function" } ] }, { "annotation": "Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8#function" }, { "database": "UniProtKB", "id": "Q0GE19", "url": "https://www.uniprot.org/uniprotkb/Q0GE19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC10A7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8", "locus": { "chromosome": "4", "start_pos": 30974486, "end_pos": 31126217, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006564", "url": "https://www.ensembl.org/id/ENSGALG00010006564" } ] } } ], "crossref": [ { "id": "Q5ZJH8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010006", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422467", "url": "https://www.ncbi.nlm.nih.gov/gene/422467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422467", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422467", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPIMIYH", "url": "https://omabrowser.org/oma/group/LPIMIYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLN1", "url": "https://www.orthodb.org/?gene=A0A8V0XLN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSZ8", "url": "https://www.orthodb.org/?gene=A0A8V0XSZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BU54", "url": "https://www.orthodb.org/?gene=E1BU54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJH8", "url": "https://www.orthodb.org/?gene=Q5ZJH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18640:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18640:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJH8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJH8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XLN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU54", "url": "https://www.uniprot.org/uniprotkb/E1BU54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU54-1", "url": "https://www.uniprot.org/uniprotkb/E1BU54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJH8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV", "length": 333, "header": "sp|Q5ZJH8-1|NTCP7_CHICK Isoform 1 of Sodium/bile acid cotransporter 7 OS=Gallus gallus OX=9031 GN=SLC10A7 PE=2 SV=1 CANONICAL=Q5ZJH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XLN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLN1/entry", "sequence": { "sequence": "MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV", "length": 317, "header": "tr|A0A8V0XLN1-1|NTCP7_CHICK Computationally mapped isoform of Sodium/bile acid cotransporter 7 OS=Gallus gallus OX=9031 GN=SLC10A7 PE=2 SV=1 CANONICAL=Q5ZJH8-1" }, "locus": { "chromosome": "4", "start_pos": 31126130, "end_pos": 30978271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015630.1", "url": "https://www.ensembl.org/id/ENSGALT00010015630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009089.1", "url": "https://www.ensembl.org/id/ENSGALP00010009089.1" } ] } }, { "isoform_ac": "A0A8V0XSZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSZ8/entry", "sequence": { "sequence": "MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV", "length": 332, "header": "tr|A0A8V0XSZ8-1|NTCP7_CHICK Computationally mapped isoform of Sodium/bile acid cotransporter 7 OS=Gallus gallus OX=9031 GN=SLC10A7 PE=2 SV=1 CANONICAL=Q5ZJH8-1" }, "locus": { "chromosome": "4", "start_pos": 31126130, "end_pos": 30978271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015652.1", "url": "https://www.ensembl.org/id/ENSGALT00010015652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009097.1", "url": "https://www.ensembl.org/id/ENSGALP00010009097.1" } ] } }, { "isoform_ac": "E1BU54-1", "url": "https://www.uniprot.org/uniprotkb/E1BU54/entry", "sequence": { "sequence": "MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV", "length": 345, "header": "tr|E1BU54-1|NTCP7_CHICK Computationally mapped isoform of Sodium/bile acid cotransporter 7 OS=Gallus gallus OX=9031 GN=SLC10A7 PE=2 SV=2 CANONICAL=Q5ZJH8-1" }, "locus": { "chromosome": "4", "start_pos": 31126130, "end_pos": 30978271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015647.1", "url": "https://www.ensembl.org/id/ENSGALT00010015647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009095.1", "url": "https://www.ensembl.org/id/ENSGALP00010009095.1" } ] } }, { "isoform_ac": "Q5ZJH8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8/entry#Q5ZJH8-1", "sequence": { "sequence": "MGLLERLRKEWFIAGIALVIAAARLEPAVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTSALMHVKLHLFVQIFTLVFFPTAIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERRKPPFGTISSCVLLMIIYTTFCDTFANPNIDLDKFSLIIIVFIIFSVQMSFMFLTFLFSTRSNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGYEHLSLISVPLLIYHPAQILLGSLLVPTIKSWMVSRQKALKLTRQPKVPVKV", "length": 333, "header": "sp|Q5ZJH8-1|NTCP7_CHICK Isoform 1 of Sodium/bile acid cotransporter 7 OS=Gallus gallus OX=9031 GN=SLC10A7 PE=2 SV=1 CANONICAL=Q5ZJH8-1" }, "locus": { "chromosome": "4", "start_pos": 31126130, "end_pos": 30978271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015641.1", "url": "https://www.ensembl.org/id/ENSGALT00010015641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009091.1", "url": "https://www.ensembl.org/id/ENSGALP00010009091.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422467", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F4IZC4-1", "protein_name": "Probable sodium/metabolite cotransporter BASS4, chloroplastic", "gene_name": "BASS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIASTLASTQNPFLCLRQPPSPGNRSVVFRRCQDPCGRRWISRSIRACQPSDKVSGQFPFDFMYSSMLIPSSCGEWNRIHLGGDGGISASAQRLYFGKELLSFASDNFLPLALVSGVGLGFANPTLGCLADKYSFTKISTCGIFIISGLTLRTEAIGAAVKGWPLGLFGLISILLLTPSFSRLIMLVQLQPRELVTGLGIFCCMPTTLSSGVALTHLAGGNAALALAVTVASNLLGILTIPFWVSRYIAGGVGVSFPTDQLFRSLIVTLLIPLIIGKVIRESFKGFANFVDNNRKLFSKINAICLSLVPWIQVSRSRSLLLSVQPKVFLAAVGIGILLHLSLLAFNAVSIRILSGLTGGSKSSKENSTAVLLVSSQKTLPVMVAVVEQLGGAFGETGLLVLPCVAAHLNQIMIDSVLVNLWLRRGKDTSTKVKTA", "length": 436 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3H9H6-1", "protein_name": "Sodium/bile acid cotransporter", "gene_name": "Slc10a7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLLERARKEWFMVGIVVAIGAAKLQPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSVTPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIIVTPLLLLLFLGSSSSVPFTAIFSQLFMTVVVPLIIGQIIRRYIKDWLERKKPPFSAVSSSVLLMIIYTTFCDTFSNPHIDLDKFSLVLILFIIVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV", "length": 340 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q05131-1", "protein_name": "Solute carrier RCH1", "gene_name": "RCH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKTQYSLIRKIWAHSVTEFLKSQWFFICLAILIVIARFAPNFARDGGLIKGQYSIGYGCVAWIFLQSGLGMKSRSLMANMLNWRAHATILVLSFLITSSIVYGFCCAVKAANDPKIDDWVLIGLILTATCPTTVASNVIMTTNAGGNSLLCVCEVFIGNLLGAFITPALVQMFTNRAPFAYGNPATGNGIGALYGRVMKQVGLSVFVPLFVGQVIQNCFPKGTAYYLGFLKKYHIKIGSYMLLLIMFSSFSTAFYQDAFTSVSHVCIIFLCFFNLGIYIFFTGLSYLCARPWFILKLFPHEPIEGKSTRLYRYSYNIFRPFYYSKEDAICIMFCGPAKTAALGVSLITSQYGDKKEHLGKLLVPLVLYQVEQVMTANFFVSLFKRWIQKDAQADGSESSCANENEEVDLEKIISIGTGENQSVLSNNVPYTQPR", "length": 434 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0GE19-2", "protein_name": "Sodium/bile acid cotransporter 7", "gene_name": "SLC10A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLERMRKDWFMVGIVLAIAGAKLEPSIGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSSVLLMIIYTTFCDTFSNPNIDLDKFSLVLILFIIFSIQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV", "length": 340 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PT50-1", "protein_name": "Sodium/bile acid cotransporter 7", "gene_name": "Slc10a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLERVRKEWFMVGIVVAIGAAKLEPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQVFTLAFFPTTIWLFLQLLSVTSINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPVLLLLFLGSSSSVPFTSIFSQLFMTVVVPLVIGQIVRRYIKDWLERKKPPFGVVSSSVLLMIIYTTFCDTFSNPNIDLDKFSLILILFIIVSIQLSFMLLTFVFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISLPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV", "length": 340 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PT53-1", "protein_name": "Sodium/bile acid cotransporter 7", "gene_name": "Slc10a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLERARKEWFMVGIVVAIGAAKLEPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLRLHLFIQIFTLAFFPAAIWLFLQLLSVTSINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPVLLLLFLGSSSSVPFTSIFSQLFMTVVVPLVIGQIVRRYIKDWLERKKPPFGVVSSSVLLMIIYTTFCDTFSNPNIDLDKFSLILILFIIVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV", "length": 340 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DHK8-1", "protein_name": "Sodium/bile acid cotransporter 7", "gene_name": "slc10a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLIARVRKEWFIIGIVLVITFAKLQPSVGVKGGPLHPEITITYVAVSVIFFNSGLSLKTEELASALMHVKLHFFVQTFTLVFFPIAIWLLLKVLALTAINEWLLRGLQTVACMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPLLLLVFLGSSSSVPFTSIFSQLFMTVVVPLIVGQVCRRFLRECLDRRKPPFGAVSSVVLLMIIYSTFCDTFNNPNIELDHLSLLTVVFIIFSIQLSFMALIFFLSTRKSSGFSAADSVAIMFCATHKSLTLGIPMLKIVFEGYEHLSLISVPLLIYHPAQILLGSVLLPSIKTWMSGRQKTLTPI", "length": 336 }, "evidence": [ { "id": "Q5ZJH8", "url": "https://omabrowser.org/oma/group/Q5ZJH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" }, { "name": "heparin proteoglycan biosynthetic process", "id": "GO:0030210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030210", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJH8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJS6-1", "uniprot_ac": "Q5ZJS6", "uniprot_id": "PAIP2_CHICK", "mass": { "chemical_mass": 15043.0, "monoisotopic_mass": 15043.0 }, "refseq": { "ac": "NP_001007833", "name": "polyadenylate-binding protein-interacting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" }, "gene_names": [ { "name": "PAIP2B", "type": "recommended", "evidence": [ { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ] }, { "name": "PAIP2", "type": "recommended", "evidence": [ { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ] }, { "name": "PAIP2B", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" } ] }, { "name": "PAIP2", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" } ] }, { "name": "RCJMB04_16b5", "type": "synonym", "evidence": [ { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ] } ], "protein_names": [ { "name": "Polyadenylate-binding protein-interacting protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6/entry#names_and_taxonomy" } ] }, { "name": "PABP-interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" }, { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6/entry#names_and_taxonomy" } ] }, { "name": "PAIP-2", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" }, { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6/entry#names_and_taxonomy" } ] }, { "name": "Poly(A)-binding protein-interacting protein 2", "type": "synonym", "evidence": [ { "id": "Q5ZJS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6/entry#names_and_taxonomy" } ] }, { "name": "poly(A) binding protein interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" } ] }, { "name": "polyadenylate-binding protein-interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001007833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720358.1, HAEK01001199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992544, SAMN06140854 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000256.1. On Dec 15, 2004 this sequence version replaced XP_414515.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833" } ] }, { "annotation": "Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XTE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE6#function" }, { "database": "UniProtKB", "id": "ARBA00037448", "url": "https://www.uniprot.org/uniprotkb/ARBA00037448#function" }, { "database": "UniProtKB", "id": "A0A8V0XTG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTG2#function" }, { "database": "UniProtKB", "id": "A0A8V0XXS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXS4#function" }, { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAIP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6", "locus": {} } ], "crossref": [ { "id": "Q5ZJS6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002488", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416187", "url": "https://www.ncbi.nlm.nih.gov/gene/416187", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416187", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416187", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGIQKHN", "url": "https://omabrowser.org/oma/group/PGIQKHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTE6", "url": "https://www.orthodb.org/?gene=A0A8V0XTE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTG2", "url": "https://www.orthodb.org/?gene=A0A8V0XTG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXS4", "url": "https://www.orthodb.org/?gene=A0A8V0XXS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y253", "url": "https://www.orthodb.org/?gene=A0A8V0Y253", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y654", "url": "https://www.orthodb.org/?gene=A0A8V0Y654", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJS6", "url": "https://www.orthodb.org/?gene=Q5ZJS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13154:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13154:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJS6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJS6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007833", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XTE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y253", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y253", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y253-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y253-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y654", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y654", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y654-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y654-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJS6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI", "length": 127, "header": "sp|Q5ZJS6-1|PAIP2_CHICK Isoform 1 of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XTE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE6/entry", "sequence": { "sequence": "MRCAEPWHSAERLILLQIKDAAMKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI", "length": 149, "header": "tr|A0A8V0XTE6-1|PAIP2_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2089544, "end_pos": 2085428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019941.1", "url": "https://www.ensembl.org/id/ENSGALT00010019941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011488.1", "url": "https://www.ensembl.org/id/ENSGALP00010011488.1" } ] } }, { "isoform_ac": "A0A8V0XTG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTG2/entry", "sequence": { "sequence": "GHAGSGSDFTSGGAAALGGERGGGHGAERSGAEQLGAGGAARPSLSAQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI", "length": 129, "header": "tr|A0A8V0XTG2-1|PAIP2_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2092674, "end_pos": 2085428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019956.1", "url": "https://www.ensembl.org/id/ENSGALT00010019956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011504.1", "url": "https://www.ensembl.org/id/ENSGALP00010011504.1" } ] } }, { "isoform_ac": "A0A8V0XXS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXS4/entry", "sequence": { "sequence": "MLKSISGLSWGVTCCAFSRFVLSAACNPLQVCLERTSRGTCVLLLEYLSVSHLLPCQGAELTSARRLQIKDAAMKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI", "length": 200, "header": "tr|A0A8V0XXS4-1|PAIP2_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2090613, "end_pos": 2085428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019949.1", "url": "https://www.ensembl.org/id/ENSGALT00010019949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011497.1", "url": "https://www.ensembl.org/id/ENSGALP00010011497.1" } ] } }, { "isoform_ac": "A0A8V0Y253-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y253/entry", "sequence": { "sequence": "MKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQASRFPLSMPHALPCRVVAVGSGAVPPDQGAGLGILLWWHFRWVC", "length": 90, "header": "tr|A0A8V0Y253-1|PAIP2_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2087708, "end_pos": 2087439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019943.1", "url": "https://www.ensembl.org/id/ENSGALT00010019943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011491.1", "url": "https://www.ensembl.org/id/ENSGALP00010011491.1" } ] } }, { "isoform_ac": "A0A8V0Y654-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y654/entry", "sequence": { "sequence": "MCMSLITAFLNCRLQIKDAAMKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQASRFPLSMPHALPCRVVAVGSGAVPPDQGAGLGILLWWHFRWVC", "length": 110, "header": "tr|A0A8V0Y654-1|PAIP2_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2086623, "end_pos": 2086294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019957.1", "url": "https://www.ensembl.org/id/ENSGALT00010019957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011505.1", "url": "https://www.ensembl.org/id/ENSGALP00010011505.1" } ] } }, { "isoform_ac": "Q5ZJS6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6/entry#Q5ZJS6-1", "sequence": { "sequence": "MKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI", "length": 127, "header": "sp|Q5ZJS6-1|PAIP2_CHICK Isoform 1 of Polyadenylate-binding protein-interacting protein 2 OS=Gallus gallus OX=9031 GN=PAIP2 PE=2 SV=1 CANONICAL=Q5ZJS6-1" }, "locus": { "chromosome": "13", "start_pos": 2089356, "end_pos": 2085428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019951.1", "url": "https://www.ensembl.org/id/ENSGALT00010019951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011499.1", "url": "https://www.ensembl.org/id/ENSGALP00010011499.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416187", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VBZ4-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "PAIP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY", "length": 124 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LKF4-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "Paip2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY", "length": 124 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZC67-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "PAIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY", "length": 124 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXZ0-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "Paip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY", "length": 124 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BPZ3-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "PAIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI", "length": 127 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6V8-1", "protein_name": "Polyadenylate-binding protein-interacting protein 2", "gene_name": "Paip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY", "length": 124 }, "evidence": [ { "id": "Q5ZJS6", "url": "https://omabrowser.org/oma/group/Q5ZJS6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "pmid": "" }, { "name": "translation repressor activity", "id": "GO:0030371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "pmid": "" }, { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJS6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 127, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJS6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJS6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZMP3-1", "uniprot_ac": "Q5ZMP3", "uniprot_id": "T184C_CHICK", "mass": { "chemical_mass": 50930.0, "monoisotopic_mass": 50930.0 }, "refseq": { "ac": "NP_001008468", "name": "transmembrane protein 184C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" }, "gene_names": [ { "name": "TMEM184C", "type": "recommended", "evidence": [ { "id": "Q5ZMP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ] }, { "name": "RCJMB04_1i7", "type": "synonym", "evidence": [ { "id": "Q5ZMP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ] }, { "name": "TMEM184C", "type": "synonym", "evidence": [ { "id": "NP_001008468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" } ] }, { "name": "TMEM34", "type": "synonym", "evidence": [ { "id": "NP_001008468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" }, { "id": "Q5ZMP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ] } ], "protein_names": [ { "name": "Transmembrane protein 184C", "type": "recommended", "evidence": [ { "id": "Q5ZMP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 34", "type": "synonym", "evidence": [ { "id": "Q5ZMP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 184C", "type": "synonym", "evidence": [ { "id": "NP_001008468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" } ] }, { "name": "transmembrane protein 34", "type": "synonym", "evidence": [ { "id": "NP_001008468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719341.1, SRR13267652.24275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Dec 16, 2004 this sequence version replaced XP_420434.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468" } ] }, { "annotation": "May play a role in cell growth.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM184C", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3", "locus": { "chromosome": "4", "start_pos": 31542927, "end_pos": 31531638, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006614", "url": "https://www.ensembl.org/id/ENSGALG00010006614" } ] } } ], "crossref": [ { "id": "Q5ZMP3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010019", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422469", "url": "https://www.ncbi.nlm.nih.gov/gene/422469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422469", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422469", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHAFVFN", "url": "https://omabrowser.org/oma/group/AHAFVFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVW9", "url": "https://www.orthodb.org/?gene=A0A8V0XVW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMP3", "url": "https://www.orthodb.org/?gene=Q5ZMP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMP3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMP3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XVW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMP3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCTCGNWRRWIRPLVVLLYIVGLLVVVPLCVWELQKLEVGIHTKAWFIAGIFLLMTIPISLWGILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPNIAIYVDTCRECYEAYVIYNFMVFLSNYLTNRYPNLVLIIEAKDQQRHLPPLCCCPSWAMGEVLLFRCKLGVLQYTVVRPFTTIIALICELVGVYDEGNFSFDNAWTYLVILNNMSQLFAMYCLVLFYKVLREELNPIQPVGKFLCVKMVVFVSFWQAVLIALLVKVGVISEKHTWEWQSVEAVATGLQDFIICVEMFLAAIAHHYSFSYKPYVQEAEEGSCFDSFLAMWDISDIRADISEQVRNVGRTVLGQPRKMFFAEDHEQNEHTSLLSSSTQDPISDASSMPSSPMGHYQGFGHTVTPLTTPTTVPVVDGIYNTSATRDTEESPELMHNSSEKALDRS", "length": 445, "header": "sp|Q5ZMP3-1|T184C_CHICK Isoform 1 of Transmembrane protein 184C OS=Gallus gallus OX=9031 GN=TMEM184C PE=2 SV=1 CANONICAL=Q5ZMP3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVW9/entry", "sequence": { "sequence": "MPCTCGNWRRWIRPLVVLLYIVGLLVVVPLCVWELQKLEVGIHTKAWFIAGIFLLMTIPISLWGILQHLVHYTQPEFLPVLSLESFLPCLRVTFCVLLFLQWIALKYPNIAIYVDTCRECYEAYVIYNFMVFLSNYLTNRYPNLVLIIEAKDQQRHLPPLCCCPSWAMGEVLLFRCKLGVLQYTVVRPFTTIIALICELVGVYDEGNFSFDNAWTYLVILNNMSQLFAMYCLVLFYKVLREELNPIQPVGKFLCVKMVVFVSFWQAVLIALLVKVGVISEKHTWEWQSVEAVATGLQDFIICVEMFLAAIAHHYSFSYKPYVQEAEEGSCFDSFLAMWDISDIRADISEQVRNVGRTVLGQPRKMFFAEDHEQNEHTSLLSSSTQDPISDASSMPSSPMGHYQGFGHTVTPLTTPTTVPVVDGIYNTSATRDTEESPELMHNSSEKALDRS", "length": 451, "header": "tr|A0A8V0XVW9-1|T184C_CHICK Computationally mapped isoform of Transmembrane protein 184C OS=Gallus gallus OX=9031 GN=TMEM184C PE=2 SV=1 CANONICAL=Q5ZMP3-1" }, "locus": { "chromosome": "4", "start_pos": 31540597, "end_pos": 31531850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015806.1", "url": "https://www.ensembl.org/id/ENSGALT00010015806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009148.1", "url": "https://www.ensembl.org/id/ENSGALP00010009148.1" } ] } }, { "isoform_ac": "Q5ZMP3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3/entry#Q5ZMP3-1", "sequence": { "sequence": "MPCTCGNWRRWIRPLVVLLYIVGLLVVVPLCVWELQKLEVGIHTKAWFIAGIFLLMTIPISLWGILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPNIAIYVDTCRECYEAYVIYNFMVFLSNYLTNRYPNLVLIIEAKDQQRHLPPLCCCPSWAMGEVLLFRCKLGVLQYTVVRPFTTIIALICELVGVYDEGNFSFDNAWTYLVILNNMSQLFAMYCLVLFYKVLREELNPIQPVGKFLCVKMVVFVSFWQAVLIALLVKVGVISEKHTWEWQSVEAVATGLQDFIICVEMFLAAIAHHYSFSYKPYVQEAEEGSCFDSFLAMWDISDIRADISEQVRNVGRTVLGQPRKMFFAEDHEQNEHTSLLSSSTQDPISDASSMPSSPMGHYQGFGHTVTPLTTPTTVPVVDGIYNTSATRDTEESPELMHNSSEKALDRS", "length": 445, "header": "sp|Q5ZMP3-1|T184C_CHICK Isoform 1 of Transmembrane protein 184C OS=Gallus gallus OX=9031 GN=TMEM184C PE=2 SV=1 CANONICAL=Q5ZMP3-1" }, "locus": { "chromosome": "4", "start_pos": 31540597, "end_pos": 31531850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015810.1", "url": "https://www.ensembl.org/id/ENSGALT00010015810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009150.1", "url": "https://www.ensembl.org/id/ENSGALP00010009150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422469", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5BPZ5-1", "protein_name": "Protein LAZ1 homolog 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGVTETSTYRDLHLPSLIIGGSFATVAICLSLYSILQHLRFYTNPAEQKWIVSVLFMVPVYATESIISLSNSKFSLPCDILRNCYEAFALYSFGSYLVACLGGERRVVEYLENESKKPLLEEGANESKKKKKKNSFWKFLCDPYVLGRELFVIEKFGLVQYMILKTFCAFLTFLLELLGVYGDGEFKWYYGYPYIVVVLNFSQMWALFCLVQFYNVTHERLKEIKPLAKFISFKAIVFATWWQGFGIALLCYYGILPKEGRFQNGLQDFLICIEMAIAAVAHLFVFPAEPYHYIPVSECGKITAETSKTEVKLEEGGLVETTETQVEASGTSIKESVQDIVIDGGQHVVKDVVLTINQAIGPVEKGVTKIQDTIHQKLLDSDGKEETEVTEEVTVETSVPPKE", "length": 403 }, "evidence": [ { "id": "Q5ZMP3", "url": "https://omabrowser.org/oma/group/Q5ZMP3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NVA4-1", "protein_name": "Transmembrane protein 184C", "gene_name": "TMEM184C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPCTCTWRNWRQWIRPLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEEGSCFDSFLAMWDVSDIRDDISEQVRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAISIASSMPPSPMGHYQGFGHTVTPQTTPTTAKISDEILSDTIGEKKEPSDKSVDS", "length": 438 }, "evidence": [ { "id": "Q5ZMP3", "url": "https://omabrowser.org/oma/group/Q5ZMP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMP3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 445, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMP3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMP3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UFA6-1", "uniprot_ac": "A0A3Q2UFA6", "uniprot_id": "A0A3Q2UFA6_CHICK", "mass": { "chemical_mass": 21834.0, "monoisotopic_mass": 21834.0 }, "refseq": {}, "gene_names": [ { "name": "TIFA", "type": "recommended", "evidence": [ { "id": "A0A3Q2UFA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ] } ], "protein_names": [ { "name": "TRAF-interacting protein with FHA domain-containing protein A", "type": "recommended", "evidence": [ { "id": "A0A3Q2UFA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIFA", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6", "locus": { "chromosome": "4", "start_pos": 56696260, "end_pos": 56685953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004065", "url": "https://www.ensembl.org/id/ENSGALG00010004065" } ] } } ], "crossref": [ { "id": "ENSGALG00000012076", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012076", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422692", "url": "https://www.ncbi.nlm.nih.gov/gene/422692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422692", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TITCLQM", "url": "https://omabrowser.org/oma/group/TITCLQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UFA6", "url": "https://www.orthodb.org/?gene=A0A3Q2UFA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMX6", "url": "https://www.orthodb.org/?gene=A0A8V0XMX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXY0", "url": "https://www.orthodb.org/?gene=E1BXY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31266:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31266:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9645460", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9645460", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXY0", "url": "https://www.uniprot.org/uniprotkb/E1BXY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BXY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSFEEDETEETATCLHMTFYHPCQQDKMMFRCLNFCKREQVRADEMAKFGRDSNVCHYNLVDTRVSRIQFSLQFYRKLNSSEFCFEIKNMSKKTKLTVDQTELGYLNKVDLPWKCIICFGDYQILAEIQEGEAMDYFETHLHLAKVPILQERCLPSLQPVPEKGIFPSLSPSQGKSPIEIDENESC", "length": 187, "header": "tr|A0A3Q2UFA6-1|A0A3Q2UFA6_CHICK Isoform 1 of TRAF-interacting protein with FHA domain-containing protein A OS=Gallus gallus OX=9031 GN=TIFA PE=3 SV=1 CANONICAL=A0A3Q2UFA6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UFA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6/entry", "sequence": { "sequence": "MTSFEEDETEETATCLHMTFYHPCQQDKMMFRCLNFCKREQVRADEMAKFGRDSNVCHYNLVDTRVSRIQFSLQFYRKLNSSEFCFEIKNMSKKTKLTVDQTELGYLNKVDLPWKCIICFGDYQILAEIQEGEAMDYFETHLHLAKVPILQERCLPSLQPVPEKGIFPSLSPSQGKSPIEIDENESC", "length": 187, "header": "tr|A0A3Q2UFA6-1|A0A3Q2UFA6_CHICK Isoform 1 of TRAF-interacting protein with FHA domain-containing protein A OS=Gallus gallus OX=9031 GN=TIFA PE=3 SV=1 CANONICAL=A0A3Q2UFA6-1" }, "locus": { "chromosome": "4", "start_pos": 56693734, "end_pos": 56693174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009445.1", "url": "https://www.ensembl.org/id/ENSGALT00010009445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005578.1", "url": "https://www.ensembl.org/id/ENSGALP00010005578.1" } ] } }, { "isoform_ac": "A0A8V0XMX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX6/entry", "sequence": { "sequence": "MDHLFKLVSKTHFIMTSFEEDETEETATCLHMTFYHPCQQDKMMFRCLNFCKREQVRADEMAKFGRDSNVCHYNLVDTRVSRIQFSLQFYRKLNSSEFCFEIKNMSKKTKLTVDQTELGYLNKVDLPWKCIICFGDYQILAEIQEGEAMDYFETHLHLAKVPILQERCLPSLQPVPEKGIFPSLSPSQGKSPIEIDENESC", "length": 201, "header": "tr|A0A8V0XMX6-1|A0A3Q2UFA6_CHICK Computationally mapped isoform of TRAF-interacting protein with FHA domain-containing protein A OS=Gallus gallus OX=9031 GN=TIFA PE=3 SV=1 CANONICAL=A0A3Q2UFA6-1" }, "locus": { "chromosome": "4", "start_pos": 56693734, "end_pos": 56691642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009433.1", "url": "https://www.ensembl.org/id/ENSGALT00010009433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005570.1", "url": "https://www.ensembl.org/id/ENSGALP00010005570.1" } ] } }, { "isoform_ac": "E1BXY0-1", "url": "https://www.uniprot.org/uniprotkb/E1BXY0/entry", "sequence": { "sequence": "MQRCTTPGFPDGSEPRCAQPACCSPALGRAATCQIRLPTASSHLASILSRAQHLRATALHTHRTHFIMTSFEEDETEETATCLHMTFYHPCQQDKMMFRCLNFCKREQVRADEMAKFGRDSNVCHYNLVDTRVSRIQFSLQFYRKLNSSEFCFEIKNMSKKTKLTVDQTELGYLNKVDLPWKCIICFGDYQILAEIQEGEAMDYFETHLHLAKVPILQERCLPSLQPVPEKGIFPSLSPSQGKSPIEIDENESC", "length": 254, "header": "tr|E1BXY0-1|A0A3Q2UFA6_CHICK Computationally mapped isoform of TRAF-interacting protein with FHA domain-containing protein A OS=Gallus gallus OX=9031 GN=TIFA PE=3 SV=3 CANONICAL=A0A3Q2UFA6-1" }, "locus": { "chromosome": "4", "start_pos": 56693734, "end_pos": 56689033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009442.1", "url": "https://www.ensembl.org/id/ENSGALT00010009442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005575.1", "url": "https://www.ensembl.org/id/ENSGALP00010005575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422692", "resource": "KEGG Pathway" }, { "id": "R-GGA-9645460", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9645460", "resource": "Reactome", "description": "Alpha-protein kinase 1 signaling pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2VDM0-1", "protein_name": "TRAF-interacting protein with FHA domain-containing protein A", "gene_name": "TIFA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSFEDADTEEMVTCLQMTLYHPGHQRSGIFRSIKFFNREKLPTSEVVKFGRNSHTCNYIFQDKQVSRVQFSLQVFKKFNSSVVSFEIKNMSKKTSLLVDNKELGYLNKMDLPDKCMIRFGDYQFLVEKEDGESLEFFEIQFSLSKKPLLQENNWLSQEPIPECGSYSSCLTQNNSPMEVGENEW", "length": 185 }, "evidence": [ { "id": "A0A3Q2UFA6", "url": "https://omabrowser.org/oma/group/A0A3Q2UFA6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q793I8-1", "protein_name": "TRAF-interacting protein with FHA domain-containing protein A", "gene_name": "Tifa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTFEDADTEETVTCLQMTIYHPGQQSGIFKSIRFCSKEKFPSIEVVKFGRNSNMCQYTFQDKQVSRIQFVLQPFKQFNSSVLSFEIKNMSKKTSLMVDNQELGYLNKMDLPYKCMLRFGEYQFLLQKEDGESVESFETQFIMSSRPLLQENNWPTQNPIPEDGMYSSYFTHRSSPSEMDENEL", "length": 184 }, "evidence": [ { "id": "A0A3Q2UFA6", "url": "https://omabrowser.org/oma/group/A0A3Q2UFA6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CG3-1", "protein_name": "TRAF-interacting protein with FHA domain-containing protein A", "gene_name": "TIFA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSFEDADTEETVTCLQMTVYHPGQLQCGIFQSISFNREKLPSSEVVKFGRNSNICHYTFQDKQVSRVQFSLQLFKKFNSSVLSFEIKNMSKKTNLIVDSRELGYLNKMDLPYRCMVRFGEYQFLMEKEDGESLEFFETQFILSPRSLLQENNWPPHRPIPEYGTYSLCSSQSSSPTEMDENES", "length": 184 }, "evidence": [ { "id": "A0A3Q2UFA6", "url": "https://omabrowser.org/oma/group/A0A3Q2UFA6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFA6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2UFA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFA6" }, { "id": "PF00498", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 121, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UGW3-1", "uniprot_ac": "A0A3Q2UGW3", "uniprot_id": "A0A3Q2UGW3_CHICK", "mass": { "chemical_mass": 91866.0, "monoisotopic_mass": 91866.0 }, "refseq": { "ac": "NP_001385000", "name": "neuroligin-4, Y-linked isoform b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" }, "gene_names": [ { "name": "NLGN4", "type": "recommended", "evidence": [ { "id": "A0A3Q2UGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3" } ] }, { "name": "NLGN4L", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "NLGN4X", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "NLGN4Y", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "NLGN4", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "neuroligin-4", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] } ], "protein_names": [ { "name": "Neuroligin 4", "type": "synonym", "evidence": [ { "id": "A0A3Q2UGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3/entry#names_and_taxonomy" } ] }, { "name": "neuroligin 4 X-linked", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "neuroligin 4, Y-linked", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "neuroligin 4-like", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "name": "neuroligin-4, Y-linked isoform b", "type": "synonym", "evidence": [ { "id": "NP_001385000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.200237.1, SRR13267659.89798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000024.1. On Dec 7, 2021 this sequence version replaced XP_015129528.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001385000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ] }, { "annotation": "Neuroligin 3 and -4 transcripts are only detected in the inner retina.", "evidence": [ { "database": "RefSeq", "id": "NP_001385000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" }, { "database": "PubMed", "id": "21031560", "url": "https://glygen.org/publication/PubMed/21031560" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGW3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NLGN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3", "locus": { "chromosome": "1", "start_pos": 127160218, "end_pos": 126994266, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001477", "url": "https://www.ensembl.org/id/ENSGALG00010001477" } ] } } ], "crossref": [ { "id": "A0A3Q2UGW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UGW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016628", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428006", "url": "https://www.ncbi.nlm.nih.gov/gene/428006", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UGW3", "url": "https://www.orthodb.org/?gene=A0A3Q2UGW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001385000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGW3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKPMGLLWLPLIFTPVCVMLNSNFLLWITALAIKFTLIDGQAQYPVVTTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGVRNATQFAAVCPQYLDERSLLNDMLPVWFTANLDTVVTYVQDQNEDCLYLNIYVPTEDDIHDQNNKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGSFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCDMLDTTDLVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVSPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYVTRRSPGKLWPATKRPAMTPANNPKHSKDTHKTAPEDTTVLIENKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV", "length": 816, "header": "tr|A0A3Q2UGW3-1|A0A3Q2UGW3_CHICK Isoform 1 of Neuroligin 4 OS=Gallus gallus OX=9031 GN=NLGN4 PE=3 SV=1 CANONICAL=A0A3Q2UGW3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGW3/entry", "sequence": { "sequence": "MSKPMGLLWLPLIFTPVCVMLNSNFLLWITALAIKFTLIDGQAQYPVVTTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGVRNATQFAAVCPQYLDERSLLNDMLPVWFTANLDTVVTYVQDQNEDCLYLNIYVPTEDDIHDQNNKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGSFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCDMLDTTDLVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVSPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYVTRRSPGKLWPATKRPAMTPANNPKHSKDTHKTAPEDTTVLIENKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV", "length": 816, "header": "tr|A0A3Q2UGW3-1|A0A3Q2UGW3_CHICK Isoform 1 of Neuroligin 4 OS=Gallus gallus OX=9031 GN=NLGN4 PE=3 SV=1 CANONICAL=A0A3Q2UGW3-1" }, "locus": { "chromosome": "1", "start_pos": 127159610, "end_pos": 127040941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003420.1", "url": "https://www.ensembl.org/id/ENSGALT00010003420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001863.1", "url": "https://www.ensembl.org/id/ENSGALP00010001863.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.", "journal": "The Journal of comparative neurology", "date": "2010-12-15", "authors": "Wahlin Karl J, Hackler Laszlo, Adler Ruben, Zack Donald J", "evidence": [ { "database": "RefSeq", "id": "NP_001385000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385000" } ], "reference": [ { "type": "PubMed", "id": "21031560", "url": "https://glygen.org/publication/PubMed/21031560" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGW3", "url": 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"https://www.uniprot.org/uniprotkb/E1C479-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFIIGRQAFCWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVAALSVEDCDPQEETFYRAMQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV", "length": 519, "header": "tr|A0A3Q2UBI6-1|A0A3Q2UBI6_CHICK Isoform 1 of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=1 CANONICAL=A0A3Q2UBI6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UBI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6/entry", "sequence": { "sequence": "MFFIIGRQAFCWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVAALSVEDCDPQEETFYRAMQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV", "length": 519, "header": "tr|A0A3Q2UBI6-1|A0A3Q2UBI6_CHICK Isoform 1 of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=1 CANONICAL=A0A3Q2UBI6-1" }, "locus": { "chromosome": "2", "start_pos": 33845004, "end_pos": 33829999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004488.1", "url": "https://www.ensembl.org/id/ENSGALT00010004488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002733.1", "url": "https://www.ensembl.org/id/ENSGALP00010002733.1" } ] } }, { "isoform_ac": "A0A8V0X486-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X486/entry", "sequence": { "sequence": "MQFCLLGWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVAALSVEDCDPQEETFYRAMQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV", "length": 515, "header": "tr|A0A8V0X486-1|A0A3Q2UBI6_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=1 CANONICAL=A0A3Q2UBI6-1" }, "locus": { "chromosome": "2", "start_pos": 33845004, "end_pos": 33833528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004486.1", "url": "https://www.ensembl.org/id/ENSGALT00010004486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002729.1", "url": "https://www.ensembl.org/id/ENSGALP00010002729.1" } ] } }, { "isoform_ac": "A0A8V0X494-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X494/entry", "sequence": { "sequence": "MWGARPRASAGDRAPLAPPGVWLWWAQRRCSAARSGPSPSTLYLWITTLTLGRNSSPKELQGSGTAAQGGGAVTVPGGWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVAALSVEDCDPQEETFYRAMQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV", "length": 586, "header": "tr|A0A8V0X494-1|A0A3Q2UBI6_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=1 CANONICAL=A0A3Q2UBI6-1" }, "locus": { "chromosome": "2", "start_pos": 33845004, "end_pos": 33825354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004504.1", "url": "https://www.ensembl.org/id/ENSGALT00010004504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002739.1", "url": "https://www.ensembl.org/id/ENSGALP00010002739.1" } ] } }, { "isoform_ac": "A0A8V0X497-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X497/entry", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALRMGKQLTRLAAHSCRRLISTTWLNELCVVKMSLSHRKQELSENMMDGKV", "length": 485, "header": "tr|A0A8V0X497-1|A0A3Q2UBI6_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=1 CANONICAL=A0A3Q2UBI6-1" }, "locus": { "chromosome": "2", "start_pos": 33863215, "end_pos": 33824857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004513.1", "url": "https://www.ensembl.org/id/ENSGALT00010004513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002744.1", "url": "https://www.ensembl.org/id/ENSGALP00010002744.1" } ] } }, { "isoform_ac": "E1C479-1", "url": "https://www.uniprot.org/uniprotkb/E1C479/entry", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSQEDAWKGCKGSIQMAVCEIQVHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSRTQKEKEFTENTEALKTKMSELRLYCNLLVQQVHKTKEASISAVSEPESGIDVGALLKSTCDTFLKTLEECMQIANTAFTSELLHQTPPGSPHLAVLRTNKIKHSVLSSHTSTERQMELNPCENGSIKAENNQQEQTLIKSLACLNLETNERSSDVSVEDHIEEGSAVMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEGIPTEEFLESCYAIVPVLDKLGPTVFAPVKMDFVGNIKKINQKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVAALSVEDCDPQEETFYRAMQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV", "length": 522, "header": "tr|E1C479-1|A0A3Q2UBI6_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family A member 8 OS=Gallus gallus OX=9031 GN=PLEKHA8 PE=4 SV=2 CANONICAL=A0A3Q2UBI6-1" }, "locus": { "chromosome": "2", "start_pos": 33845004, "end_pos": 33824857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004507.1", "url": "https://www.ensembl.org/id/ENSGALT00010004507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002741.1", "url": "https://www.ensembl.org/id/ENSGALP00010002741.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZY60-1", "protein_name": "Pleckstrin homology domain-containing family A member 8", "gene_name": "Plekha8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVATAGVADSEEGIDVGTLLRSTCNTFLKTLEECMQIANAAFTSELLYHTPPGSPQLAVLKSSKMKHPIIPIHNSLERPIELNSCENGSLSVEVNGDEELLMKTKKSSLYLKSTKADCNISSEENTDGNTTVQGERMKEDGEENLESHDRDLAQPGSDSVCSPESPWEDSEEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVARVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTIKEGDHQKEAFSAGMQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV", "length": 520 }, "evidence": [ { "id": "A0A3Q2UBI6", "url": "https://omabrowser.org/oma/group/A0A3Q2UBI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MS15-1", "protein_name": "Pleckstrin homology domain-containing family A member 8", "gene_name": "PLEKHA8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVTTTGVSSSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSELLYRTPPGSPQLAMLKSNKMKHPIVPIHNSLERQMELNSCENGSLNMEINDDEEILVRNKSSLCLKPAETDCSISSEENTDDNITVQGEMMKENGEESLGNHDSDLAQPELHSTSSSPESHWEEDQEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTIKEGDHQKAAFSVGMQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV", "length": 520 }, "evidence": [ { "id": "A0A3Q2UBI6", "url": "https://omabrowser.org/oma/group/A0A3Q2UBI6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80W71-1", "protein_name": "Pleckstrin homology domain-containing family A member 8", "gene_name": "Plekha8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVATAGVTDSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSELLYHTPPGSPQLAVLKSSKMKHPIIPIHNSLERSMELNSCENGSLSIEVNGDEEILMKTKSSLYLKSTEVDCSISSEENTDDNVTVQGEIMKEDGEENLESHDKDPAQPGSDSVCSPESPWEDNEEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTIKEGDHQKEAFSAGMQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV", "length": 519 }, "evidence": [ { "id": "A0A3Q2UBI6", "url": "https://omabrowser.org/oma/group/A0A3Q2UBI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JA3-1", "protein_name": "Pleckstrin homology domain-containing family A member 8", "gene_name": "PLEKHA8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSELLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNKNSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECLWEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTVKEGDHQKEAFSIGMQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV", "length": 519 }, "evidence": [ { "id": "A0A3Q2UBI6", "url": "https://omabrowser.org/oma/group/A0A3Q2UBI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "ceramide 1-phosphate binding", "id": "GO:1902387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902387", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transfer activity", "id": "GO:1902388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902388", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "glycolipid binding", "id": "GO:0051861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051861", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "cerebroside transfer activity", "id": "GO:0140340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140340", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "globoside biosynthetic process", "id": "GO:0001576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "ER to Golgi ceramide transport", "id": "GO:0035621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035621", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TVJ3-1", "uniprot_ac": "A0A3Q2TVJ3", "uniprot_id": "A0A3Q2TVJ3_CHICK", "mass": { "chemical_mass": 42904.0, "monoisotopic_mass": 42904.0 }, "refseq": { "ac": "XP_425554", "name": "ATP-sensitive inward rectifier potassium channel 15 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425554" }, "gene_names": [ { "name": "KCNJ15", "type": "recommended", "evidence": [ { "id": "A0A3Q2TVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ] }, { "name": "KCNJ15", "type": "synonym", "evidence": [ { "id": "XP_425554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425554" } ] } ], "protein_names": [ { "name": "ATP-sensitive inward rectifier potassium channel 15 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_425554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425554" } ] }, { "name": "Potassium inwardly rectifying channel subfamily J member 15", "type": "synonym", "evidence": [ { "id": "A0A3Q2TVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_425554.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425554" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNJ15", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3", "locus": { "chromosome": "1", "start_pos": 107625209, "end_pos": 107585374, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013304", "url": "https://www.ensembl.org/id/ENSGALG00010013304" } ] } } ], "crossref": [ { "id": "ENSGALG00000016055", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016055", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427984", "url": "https://www.ncbi.nlm.nih.gov/gene/427984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TVJ3", "url": "https://www.orthodb.org/?gene=A0A3Q2TVJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_425554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 375, "header": "tr|A0A3Q2TVJ3-1|A0A3Q2TVJ3_CHICK Isoform 1 of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TVJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3/entry", "sequence": { "sequence": "MEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 375, "header": "tr|A0A3Q2TVJ3-1|A0A3Q2TVJ3_CHICK Isoform 1 of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "locus": { "chromosome": "1", "start_pos": 107622336, "end_pos": 107621212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032005.1", "url": "https://www.ensembl.org/id/ENSGALT00010032005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018795.1", "url": "https://www.ensembl.org/id/ENSGALP00010018795.1" } ] } }, { "isoform_ac": "A0A8V0YDD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDD8/entry", "sequence": { "sequence": "MERTEAVRMEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 383, "header": "tr|A0A8V0YDD8-1|A0A3Q2TVJ3_CHICK Computationally mapped isoform of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "locus": { "chromosome": "1", "start_pos": 107622336, "end_pos": 107585801, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032014.1", "url": "https://www.ensembl.org/id/ENSGALT00010032014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018804.1", "url": "https://www.ensembl.org/id/ENSGALP00010018804.1" } ] } }, { "isoform_ac": "A0A8V0YIZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ8/entry", "sequence": { "sequence": "MDKRTEAVRMEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 384, "header": "tr|A0A8V0YIZ8-1|A0A3Q2TVJ3_CHICK Computationally mapped isoform of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "locus": { "chromosome": "1", "start_pos": 107622336, "end_pos": 107602392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032008.1", "url": "https://www.ensembl.org/id/ENSGALT00010032008.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018798.1", "url": "https://www.ensembl.org/id/ENSGALP00010018798.1" } ] } }, { "isoform_ac": "A0A8V0YJ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ05/entry", "sequence": { "sequence": "MTSNQCQEHRWSRVLLWQNMEKLQTEAVRMEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 404, "header": "tr|A0A8V0YJ05-1|A0A3Q2TVJ3_CHICK Computationally mapped isoform of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "locus": { "chromosome": "1", "start_pos": 107622336, "end_pos": 107589128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032013.1", "url": "https://www.ensembl.org/id/ENSGALT00010032013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018803.1", "url": "https://www.ensembl.org/id/ENSGALP00010018803.1" } ] } }, { "isoform_ac": "A0A8V0YLM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM9/entry", "sequence": { "sequence": "MPIRTEAVRMEATQINMSRVPLVNGGISTALKAHKPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFLHGDLEINKFTSKREPCVKNVDSLTGAFLFSLESQTTIGYGFRFITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKHNGELCLVIRVANMRKSLLIQCQLSGKLLQTYETKEGERILLNQASVKFNVDSSSESPFLILPLTFYHILDESSPLRDLTPQNLKDKDFELVVLLNATVESTSAVCQSRTSYIPDEIHWGYEFVPVVSLSPNGKYVADFSQFEKIRRSTDSSFYSVDSEKQKLEEKYRQEDQRERELRTMLLQQSNV", "length": 384, "header": "tr|A0A8V0YLM9-1|A0A3Q2TVJ3_CHICK Computationally mapped isoform of Potassium inwardly rectifying channel subfamily J member 15 OS=Gallus gallus OX=9031 GN=KCNJ15 PE=3 SV=1 CANONICAL=A0A3Q2TVJ3-1" }, "locus": { "chromosome": "1", "start_pos": 107622336, "end_pos": 107608031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032007.1", "url": "https://www.ensembl.org/id/ENSGALT00010032007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018797.1", "url": "https://www.ensembl.org/id/ENSGALP00010018797.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1296041", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296041", "resource": "Reactome", "description": "Activation of G protein gated Potassium channels" }, { "id": "R-GGA-997272", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-997272", "resource": "Reactome", "description": "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" }, { "id": "PF17655", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Inward rectifier potassium channel C-terminal", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 346, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q2TVJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVJ3" }, { "id": "PF01007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel inwardly rectifying transmembrane", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 171, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RRQ3-1", "uniprot_ac": "A0A1L1RRQ3", "uniprot_id": "A0A1L1RRQ3_CHICK", "mass": { "chemical_mass": 91037.0, "monoisotopic_mass": 91037.0 }, "refseq": { "ac": "XP_015145925", "name": "kinesin-associated protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145925" }, "gene_names": [ { "name": "KIFAP3", "type": "recommended", "evidence": [ { "id": "A0A1L1RRQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ] }, { "name": "KIFAP3", "type": "synonym", "evidence": [ { "id": "XP_015145925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145925" } ] } ], "protein_names": [ { "name": "Kinesin associated protein 3", "type": "synonym", "evidence": [ { "id": "A0A1L1RRQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3/entry#names_and_taxonomy" } ] }, { "name": "kinesin-associated protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015145925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145925" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145925" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIFAP3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3", "locus": { "chromosome": "8", "start_pos": 5059459, "end_pos": 4991925, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014204", "url": "https://www.ensembl.org/id/ENSGALG00010014204" } ] } } ], "crossref": [ { "id": "A0A1L1RRQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RRQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021047", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021047", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424395", "url": "https://www.ncbi.nlm.nih.gov/gene/424395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RRQ3", "url": "https://www.orthodb.org/?gene=A0A1L1RRQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGU1", "url": "https://www.orthodb.org/?gene=A0A8V0YGU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGV2", "url": "https://www.orthodb.org/?gene=A0A8V0YGV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGV8", "url": "https://www.orthodb.org/?gene=A0A8V0YGV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN15", "url": "https://www.orthodb.org/?gene=A0A8V0YN15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN81", "url": "https://www.orthodb.org/?gene=A0A8V0YN81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ11", "url": "https://www.orthodb.org/?gene=A0A8V0YQ11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3C8", "url": "https://www.orthodb.org/?gene=E1C3C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15605:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15605:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983189", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015145925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RRQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3C8", "url": "https://www.uniprot.org/uniprotkb/E1C3C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3C8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 793, "header": "tr|A0A1L1RRQ3-1|A0A1L1RRQ3_CHICK Isoform 1 of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=2 CANONICAL=A0A1L1RRQ3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RRQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3/entry", "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 793, "header": "tr|A0A1L1RRQ3-1|A0A1L1RRQ3_CHICK Isoform 1 of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=2 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5057485, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034220.1", "url": "https://www.ensembl.org/id/ENSGALT00010034220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020102.1", "url": "https://www.ensembl.org/id/ENSGALP00010020102.1" } ] } }, { "isoform_ac": "A0A8V0YGU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU1/entry", "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSRVAWTSL", "length": 764, "header": "tr|A0A8V0YGU1-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5044134, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034197.1", "url": "https://www.ensembl.org/id/ENSGALT00010034197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020090.1", "url": "https://www.ensembl.org/id/ENSGALP00010020090.1" } ] } }, { "isoform_ac": "A0A8V0YGV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV2/entry", "sequence": { "sequence": "MQGEDARYLKSIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 749, "header": "tr|A0A8V0YGV2-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5057485, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034216.1", "url": "https://www.ensembl.org/id/ENSGALT00010034216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020100.1", "url": "https://www.ensembl.org/id/ENSGALP00010020100.1" } ] } }, { "isoform_ac": "A0A8V0YGV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV8/entry", "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNEAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 760, "header": "tr|A0A8V0YGV8-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5057485, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034223.1", "url": "https://www.ensembl.org/id/ENSGALT00010034223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020105.1", "url": "https://www.ensembl.org/id/ENSGALP00010020105.1" } ] } }, { "isoform_ac": "A0A8V0YN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN15/entry", "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSLYQEKLPSTQLMSAVQHTALATKSPRCAGAHR", "length": 790, "header": "tr|A0A8V0YN15-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5047547, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034205.1", "url": "https://www.ensembl.org/id/ENSGALT00010034205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020094.1", "url": "https://www.ensembl.org/id/ENSGALP00010020094.1" } ] } }, { "isoform_ac": "A0A8V0YN81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN81/entry", "sequence": { "sequence": "MVAVLRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 788, "header": "tr|A0A8V0YN81-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5057485, "end_pos": 4995255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034212.1", "url": "https://www.ensembl.org/id/ENSGALT00010034212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020097.1", "url": "https://www.ensembl.org/id/ENSGALP00010020097.1" } ] } }, { "isoform_ac": "A0A8V0YQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ11/entry", "sequence": { "sequence": "MSSLLQVNWHLTTFLLRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSIGVDGFGQSPGVPGRPATAYGYRPDEPYYYGYGAR", "length": 799, "header": "tr|A0A8V0YQ11-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=1 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5057485, "end_pos": 4992550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034226.1", "url": "https://www.ensembl.org/id/ENSGALT00010034226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020108.1", "url": "https://www.ensembl.org/id/ENSGALP00010020108.1" } ] } }, { "isoform_ac": "E1C3C8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3C8/entry", "sequence": { "sequence": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGETGDPMLGERKECQKIIRLKSLNANTDIASLARKVVEECKLIHPSKLAEVEQLLYYLQNRRDASAGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLINETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGIITHYKIGALCMNIIDHELKRHELWQEELAKKKKAVDEDPENQTLKKDYEKTYKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMVPCEHEDLLNITLRLLLNLSFDTSLRNKMVQVGLLPKLTALLANENYKQVAMCILYHISMDDRFKSMFAYTDCIPQLMKMLFECPDERVDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTLPDLDWELVLKEYKLVPYLKDKLKPGSAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNAEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDDSEQYLYGDDPIEPYIHEGDILERPDLYYNADGLIAPDGAVSPDFFSDYHLQNGDLVGQHPFSSSLCVFWEES", "length": 766, "header": "tr|E1C3C8-1|A0A1L1RRQ3_CHICK Computationally mapped isoform of Kinesin associated protein 3 OS=Gallus gallus OX=9031 GN=KIFAP3 PE=1 SV=4 CANONICAL=A0A1L1RRQ3-1" }, "locus": { "chromosome": "8", "start_pos": 5041933, "end_pos": 4995083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034192.1", "url": "https://www.ensembl.org/id/ENSGALT00010034192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020086.1", "url": "https://www.ensembl.org/id/ENSGALP00010020086.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 17, "go_terms": [ { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "kinesin II complex", "id": "GO:0016939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016939", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "periciliary membrane compartment", "id": "GO:1990075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990075", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "intraciliary transport particle B binding", "id": "GO:0120170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120170", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "anterograde dendritic transport of neurotransmitter receptor complex", "id": "GO:0098971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098971", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 530, "end_pos": 532 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U8C8-1", "uniprot_ac": "A0A3Q2U8C8", "uniprot_id": "A0A3Q2U8C8_CHICK", "mass": { "chemical_mass": 50073.0, "monoisotopic_mass": 50073.0 }, "refseq": { "ac": "XP_004949212", "name": "protein prenyltransferase alpha subunit repeat-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949212" }, "gene_names": [ { "name": "PTAR1", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8" } ] }, { "name": "PTAR1", "type": "synonym", "evidence": [ { "id": "XP_004949212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949212" } ] } ], "protein_names": [ { "name": "Protein prenyltransferase alpha subunit repeat containing 1", "type": "synonym", "evidence": [ { "id": "A0A3Q2U8C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8/entry#names_and_taxonomy" } ] }, { "name": "protein prenyltransferase alpha subunit repeat-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949212" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949212" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8C8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTAR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8", "locus": { "chromosome": "Z", "start_pos": 35381331, "end_pos": 35440327, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014914", "url": "https://www.ensembl.org/id/ENSGALG00010014914" } ] } } ], "crossref": [ { "id": "A0A3Q2U8C8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015113", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015113", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "431607", "url": "https://www.ncbi.nlm.nih.gov/gene/431607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431607", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCNTEQR", "url": "https://omabrowser.org/oma/group/CCNTEQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U8C8", "url": "https://www.orthodb.org/?gene=A0A3Q2U8C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIT2", "url": "https://www.orthodb.org/?gene=A0A8V0YIT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIU2", "url": "https://www.orthodb.org/?gene=A0A8V0YIU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ75", "url": "https://www.orthodb.org/?gene=A0A8V0YQ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ80", "url": "https://www.orthodb.org/?gene=A0A8V0YQ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX03", "url": "https://www.orthodb.org/?gene=A0A8V0YX03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NK31", "url": "https://www.orthodb.org/?gene=F1NK31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11129:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11129:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01239", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01239", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8C8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NK31", "url": "https://www.uniprot.org/uniprotkb/F1NK31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NK31-1", "url": "https://www.uniprot.org/uniprotkb/F1NK31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESPEEVAVLVQRVVKDIRNAFKRNPDIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 435, "header": "tr|A0A3Q2U8C8-1|A0A3Q2U8C8_CHICK Isoform 1 of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8/entry", "sequence": { "sequence": "MAESPEEVAVLVQRVVKDIRNAFKRNPDIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 435, "header": "tr|A0A3Q2U8C8-1|A0A3Q2U8C8_CHICK Isoform 1 of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35440267, "end_pos": 35413394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035884.1", "url": "https://www.ensembl.org/id/ENSGALT00010035884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020818.1", "url": "https://www.ensembl.org/id/ENSGALP00010020818.1" } ] } }, { "isoform_ac": "A0A8V0YIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT2/entry", "sequence": { "sequence": "MGDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 408, "header": "tr|A0A8V0YIT2-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35439851, "end_pos": 35413394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035882.1", "url": "https://www.ensembl.org/id/ENSGALT00010035882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020816.1", "url": "https://www.ensembl.org/id/ENSGALP00010020816.1" } ] } }, { "isoform_ac": "A0A8V0YIU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU2/entry", "sequence": { "sequence": "MAESPEEVAVLVQRVVKDIRNAFKRNPDIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKCEHVYVQVGKWRNGVHVTSGRE", "length": 449, "header": "tr|A0A8V0YIU2-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35440267, "end_pos": 35407034, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035893.1", "url": "https://www.ensembl.org/id/ENSGALT00010035893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020826.1", "url": "https://www.ensembl.org/id/ENSGALP00010020826.1" } ] } }, { "isoform_ac": "A0A8V0YQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ75/entry", "sequence": { "sequence": "MHYIMLCVRKYDLLLACLLRDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 426, "header": "tr|A0A8V0YQ75-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35438947, "end_pos": 35413394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035880.1", "url": "https://www.ensembl.org/id/ENSGALT00010035880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020815.1", "url": "https://www.ensembl.org/id/ENSGALP00010020815.1" } ] } }, { "isoform_ac": "A0A8V0YQ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ80/entry", "sequence": { "sequence": "MAESPEEVAVLVQRVVKDIRNAFKRNPDIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 400, "header": "tr|A0A8V0YQ80-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35440267, "end_pos": 35413394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035886.1", "url": "https://www.ensembl.org/id/ENSGALT00010035886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020820.1", "url": "https://www.ensembl.org/id/ENSGALP00010020820.1" } ] } }, { "isoform_ac": "A0A8V0YX03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX03/entry", "sequence": { "sequence": "MAESPEEVAVLVQRVVKDIRNAFKRNPDIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKCCVKLLQTFRTGRTVKWGGEDSIVSVAVYCTCIARPVE", "length": 465, "header": "tr|A0A8V0YX03-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=1 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35440267, "end_pos": 35381333, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035895.1", "url": "https://www.ensembl.org/id/ENSGALT00010035895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020827.1", "url": "https://www.ensembl.org/id/ENSGALP00010020827.1" } ] } }, { "isoform_ac": "F1NK31-1", "url": "https://www.uniprot.org/uniprotkb/F1NK31/entry", "sequence": { "sequence": "MSLDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLNKDELIDTTCTLLLLNPDFTTAWNVRKELILSGTLSPLKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQENSLPVLVNKGNLGAAPVERIHRLVQEEMDVCSEAAGRYPSNYNAWSHRIWVLQNVGKLTIKILLDELSSTKYWVSMHVSDHSGFHYRQFLLKSLIGRTVNDDNTLVQNQMGNEQNSSLQTEEECEGAEAVCVEEQSVDIPRYLEEELDFCTDLIDTYPGHETLWCHRRRVFYLQHHLINKLPLLSVVVSSVDSSDETLHNSHPNPATSHMAQAMDVDGLNESSSKQGYTQETKRLKRAPMQDSLGPEVEYRFIEKVLSTCRDVDQARFATAYRKWLVTFLGQ", "length": 409, "header": "tr|F1NK31-1|A0A3Q2U8C8_CHICK Computationally mapped isoform of Protein prenyltransferase alpha subunit repeat containing 1 OS=Gallus gallus OX=9031 GN=PTAR1 PE=3 SV=4 CANONICAL=A0A3Q2U8C8-1" }, "locus": { "chromosome": "Z", "start_pos": 35431916, "end_pos": 35413394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035890.1", "url": "https://www.ensembl.org/id/ENSGALT00010035890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020823.1", "url": "https://www.ensembl.org/id/ENSGALP00010020823.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5T5-1", "protein_name": "Protein prenyltransferase alpha subunit repeat containing 1", "gene_name": "PTAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNKDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLRQLIQETSLPSFMTKGNLGIIPAERTQQLIREEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVTDGSISEQNPLRSEPGIVLPKGEEAVASAEESRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHLNSPHTSQAMEVDGLSDSSKQGYSQETKRLKRTPAPDSLGLEMEHRFIDQVLSTCRNVEQARFANAYRKWLVTLSQ", "length": 401 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A494B9V8-1", "protein_name": "Protein prenyltransferase alpha subunit repeat containing 1", "gene_name": "Ptar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESNEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNKDELADVTCTLLLLNPDFTTAWNVRKELILSGTLSPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLSQETFLPSSVAKGSLGAVPAERTQRIIQEEMEVCSEAAGRYPSNYNAWSHRIWVLQNVAKLDLKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTTIDSAVPQHNSLKSEPKDEAAAASTEEPSVNLPQLLEEEVEFCTDLIDSYPGHETLWCHRRHVFYLQHHLNGRLPPNLTHLSPADCPGGALNDSLQIPTSPQLSQAMEVDGLSDSSKQGYSQETKRLKRTPAPDSLGLEMEHRFIDQVLSTCRNVEQVRYANAYRKWLVTLSQ", "length": 424 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KPW7-1", "protein_name": "Protein prenyltransferase alpha subunit repeat-containing protein 1", "gene_name": "ptar1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESEEEVDVLVQRVVKDITNAFKRNPNIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRQRKQWLDREALVDITSTLLLLNPDFTTAWNVRKELLQCGVLNPEKDLYLGKLALSKHPKSPETWIHRRWVLQRLQKECSPSGQELKDSAESRRQCERLQRALQEEMRVCAEAAGRYPSNYNAWSHRIWVLQNMAKGNLKVLHDELSSTRLWVSMHVSDHSGFHYRQHLLKALAKELSPAAEKDVHTSQQPNGENTATASDDNHHKDVMPRLFHEEIQLCTDLIESYPGHETLWCHRRHVFYLWHQWRREHMQGAGSQSPALTHTDVLLSKELCDNNSISQAMDIDCVLDGSKHGSYTQDTKRLKRGPLLLQPGFPSEHTFISRILTGCRNPEQSRFAIAYRKWLDSVIGQ", "length": 426 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZWG9-1", "protein_name": "Protein prenyltransferase alpha subunit repeat containing 1", "gene_name": "Ptar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VERPALPGSSGAGRGRALVHSPRPPGAHARFRQAERGWDCRARPAGRYQDAWRVSVGERPRRATSERGVFALPGASLELWQLFSPLPSAGVRLPGGPLLWGSVPWRRLSGCIQDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLHKDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLSPVKDLHLGKLALTKFPKSPETWIHRRWVLQQLSQETSLPSSVAKGSLGVVPAERTQRIIQEEMEVCSEAAGRYPSNYNAWSHRIWVLQNVAKLDLKILLDELSSTKHWASVHVSDHSGFHYRQFLLKSLISQTTTDNAVPQHNSLKCEPKEAAAAAASAEEPSVSLPQLLEEEVEFCTDLIDSYPGHETLWCHRRHVFYLQHHLNGRLPPSLTPLSPADCSGAALNDLHQIPTSPQLSQAMEVDGLSDSSKQGYSQETKRLKRTPAPDSLGLEMEHKFIDQVLSTCRNVEQARYANAYRKWLVTLSQ", "length": 509 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54KV5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASVESKVQESKKLYDELNLIFINNPEINEIGFVMSSKDYDGLENKPFVLVENKLGISFQWMIKLYSYALTYFTELKSAFEKKMNDLPERHQQLLVNELLQATRNVLLINAENLTALNLRKELINLKYIKHKDEISLLNLIFTKHPKSGEGWAHRKWVITDYFKKTGDYLDYEIELAVCKRVAEIYPKNYYSWTHRWWILQHLSVDIILKDLETMEDWVKRNISDYCGYHHRYLILTHLFNKCYNSNDDNNNNESKSEENSNEMKIHKLWEDEFNFIHKIINLYPGHESSWSYKRVLTLFWLQIAQPIVFQRNISTTVPITSLQQESQFVDSILEDIDSSYYEQQKSFAQRYLLSIYELKFKDSADFSIDIDQVKNNYSIIINDLKISFPNQLKVWEYKLNQFVGQ", "length": 406 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z6K3-1", "protein_name": "Protein prenyltransferase alpha subunit repeat-containing protein 1", "gene_name": "PTAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHLNAGSQLSQAMEVDGLNDSSKQGYSQETKRLKRTPVPDSLGLEMEHRFIDQVLSTCRNVEQARFASAYRKWLVTLSQ", "length": 402 }, "evidence": [ { "id": "A0A3Q2U8C8", "url": "https://omabrowser.org/oma/group/A0A3Q2U8C8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein prenyltransferase activity", "id": "GO:0008318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008318", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8C8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8C8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8C8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZM2-1", "uniprot_ac": "A0A1L1RZM2", "uniprot_id": "A0A1L1RZM2_CHICK", "mass": { "chemical_mass": 123392.0, "monoisotopic_mass": 123392.0 }, "refseq": { "ac": "NP_001309297", "name": "disheveled-associated activator of morphogenesis 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" }, "gene_names": [ { "name": "DAAM1", "type": "recommended", "evidence": [ { "id": "A0A1L1RZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ] }, { "name": "DAAM1", "type": "synonym", "evidence": [ { "id": "NP_001309297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" } ] } ], "protein_names": [ { "name": "Dishevelled associated activator of morphosis 1", "type": "synonym", "evidence": [ { "id": "A0A1L1RZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2/entry#names_and_taxonomy" } ] }, { "name": "disheveled-associated activator of morphogenesis 1", "type": "synonym", "evidence": [ { "id": "NP_001309297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: SRR13267649.186281.1 [ECO:0000331] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On Apr 12, 2016 this sequence version replaced XP_015142988.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001309297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" } ] }, { "annotation": "Involved in pivotal steps in neuronal cell differentiation and movement [Daam1]", "evidence": [ { "database": "RefSeq", "id": "NP_001309297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" }, { "database": "PubMed", "id": "15464228", "url": "https://glygen.org/publication/PubMed/15464228" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DAAM1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2", "locus": { "chromosome": "5", "start_pos": 54324214, "end_pos": 54405134, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017098", "url": "https://www.ensembl.org/id/ENSGALG00010017098" } ] } } ], "crossref": [ { "id": "A0A1L1RZM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RZM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012017", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012017", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423532", "url": "https://www.ncbi.nlm.nih.gov/gene/423532", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423532", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423532", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMLYFQE", "url": "https://omabrowser.org/oma/group/AMLYFQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZM2", "url": "https://www.orthodb.org/?gene=A0A1L1RZM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YSZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZD8", "url": "https://www.orthodb.org/?gene=A0A8V0YZD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45725:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45725:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001309297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRKRSGRGISFIFCCFRSSDHPEITYRLRNDSSFALQTMEPALPMPPVEELDVMFTELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLIALEKEEEEERNKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKSMDYETAESRIHTSLIGCIKALMNNSLGRAHVLAHSESINVIAQSLSTENIKTKVAVLEIMGAVCLVPGGHKKVLEAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHTEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQSDKGQDPDATPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHTELQQKLEKKERECDAKAQEKEEMMQTLNKMKEKLEKESSEHKQVKQQVADLTAQLHEMSRRAICAAGPGGPPLPPGAPGGPLPSPAPGSLLPPPPPPPPPGGCPPPPPPPPPPPGGPPPPPGPPPLDGVMPPPGAPLGFALKKKSIPQPTNALKSFNWSKLPENKLAGTVWTDIDDAKVFKILDLEDLERTFSAYQRQQDFFVSSNSRQKEDAIDDTLSSRHKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQLLKFVPEKGDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRAGSKAVLQSSSLQQLLEVVLAFGNYMNKGQRGNAFGFKISSLNKIADTKSSIDKNITLLHYLITIVEKKYPKVLRLHEELRDIPQAAKVNMTELEKEVNTLRSGLRAVETELDFQKSQVQQTGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFSKAVKHFGEDTDKMQPDEFFGIFDQFLQAVTEAKQENENMRRRKEEEERRARMEAQLKEQRERERKARKAKESGEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRIANQLADSGRERPITKLNF", "length": 1080, "header": "tr|A0A1L1RZM2-1|A0A1L1RZM2_CHICK Isoform 1 of Dishevelled associated activator of morphosis 1 OS=Gallus gallus OX=9031 GN=DAAM1 PE=4 SV=1 CANONICAL=A0A1L1RZM2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2/entry", "sequence": { "sequence": "MAPRKRSGRGISFIFCCFRSSDHPEITYRLRNDSSFALQTMEPALPMPPVEELDVMFTELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLIALEKEEEEERNKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKSMDYETAESRIHTSLIGCIKALMNNSLGRAHVLAHSESINVIAQSLSTENIKTKVAVLEIMGAVCLVPGGHKKVLEAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHTEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQSDKGQDPDATPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHTELQQKLEKKERECDAKAQEKEEMMQTLNKMKEKLEKESSEHKQVKQQVADLTAQLHEMSRRAICAAGPGGPPLPPGAPGGPLPSPAPGSLLPPPPPPPPPGGCPPPPPPPPPPPGGPPPPPGPPPLDGVMPPPGAPLGFALKKKSIPQPTNALKSFNWSKLPENKLAGTVWTDIDDAKVFKILDLEDLERTFSAYQRQQDFFVSSNSRQKEDAIDDTLSSRHKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQLLKFVPEKGDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRAGSKAVLQSSSLQQLLEVVLAFGNYMNKGQRGNAFGFKISSLNKIADTKSSIDKNITLLHYLITIVEKKYPKVLRLHEELRDIPQAAKVNMTELEKEVNTLRSGLRAVETELDFQKSQVQQTGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFSKAVKHFGEDTDKMQPDEFFGIFDQFLQAVTEAKQENENMRRRKEEEERRARMEAQLKEQRERERKARKAKESGEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRIANQLADSGRERPITKLNF", "length": 1080, "header": "tr|A0A1L1RZM2-1|A0A1L1RZM2_CHICK Isoform 1 of Dishevelled associated activator of morphosis 1 OS=Gallus gallus OX=9031 GN=DAAM1 PE=4 SV=1 CANONICAL=A0A1L1RZM2-1" }, "locus": { "chromosome": "5", "start_pos": 54374233, "end_pos": 54326741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041280.1", "url": "https://www.ensembl.org/id/ENSGALT00010041280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024168.1", "url": "https://www.ensembl.org/id/ENSGALP00010024168.1" } ] } }, { "isoform_ac": "A0A8V0YSZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ5/entry", "sequence": { "sequence": "MSHCAVWMIFSRKTDCSIVLPWAGLSSLLMHCRRDSCAVLLLGSSAQQGGTWSVLAMAPRKRSGRGISFIFCCFRSSDHPEITYRLRNDSSFALQTMEPALPMPPVEELDVMFTELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLIALEKEEEEERNKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKSMDYETAESRIHTSLIGCIKALMNNSLGRAHVLAHSESINVIAQSLSTENIKTKVAVLEIMGAVCLVPGGHKKVLEAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHTEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQSDKGQDPDATPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHTELQQKLEKKERECDAKAQEKEEMMQTLNKMKEKLEKESSEHKQVKQQVADLTAQLHEMSRRAICAAGPGGPPLPPGAPGGPLPSPAPGSLLPPPPPPPPPGGCPPPPPPPPPPPGGPPPPPGPPPLDGVMPPPGAPLGFALKKKSIPQPTNALKSFNWSKLPENKLAGTVWTDIDDAKVFKILDLEDLERTFSAYQRQQKEDAIDDTLSSRHKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQLLKFVPEKGDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRAGSKAVLQSSSLQQLLEVVLAFGNYMNKGQRGNAFGFKISSLNKIADTKSSIDKNITLLHYLITIVEKKYPKVLRLHEELRDIPQAAKVNMTELEKEVNTLRSGLRAVETELDFQKSQVQQTGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFSKAVKHFGEDTDKMQPDEFFGIFDQFLQAVTEAKQENENMRRRKEEEERRARMEAQLKEQRERERKARKAKESGEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRIANQLADSGRERPITKLNF", "length": 1126, "header": "tr|A0A8V0YSZ5-1|A0A1L1RZM2_CHICK Computationally mapped isoform of Dishevelled associated activator of morphosis 1 OS=Gallus gallus OX=9031 GN=DAAM1 PE=4 SV=1 CANONICAL=A0A1L1RZM2-1" }, "locus": { "chromosome": "5", "start_pos": 54381860, "end_pos": 54326741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041274.1", "url": "https://www.ensembl.org/id/ENSGALT00010041274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024165.1", "url": "https://www.ensembl.org/id/ENSGALP00010024165.1" } ] } }, { "isoform_ac": "A0A8V0YZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD8/entry", "sequence": { "sequence": "MKESLPTGGCWWMFRSAFKGSSAQQGGTWSVLAMAPRKRSGRGISFIFCCFRSSDHPEITYRLRNDSSFALQTMEPALPMPPVEELDVMFTELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLIALEKEEEEERNKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKSMDYETAESRIHTSLIGCIKALMNNSLGRAHVLAHSESINVIAQSLSTENIKTKVAVLEIMGAVCLVPGGHKKVLEAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHTEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQSDKGQDPDATPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHTELQQKLEKKERECDAKAQEKEEMMQTLNKMKEKLEKESSEHKQVKQQVADLTAQLHEMSRRAICAAGPGGPPLPPGAPGGPLPSPAPGSLLPPPPPPPPPGGCPPPPPPPPPPPGGPPPPPGPPPLDGVMPPPGAPLGFALKKKSIPQPTNALKSFNWSKLPENKLAGTVWTDIDDAKVFKILDLEDLERTFSAYQRQQKEDAIDDTLSSRHKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQLLKFVPEKGDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRAGSKAVLQSSSLQQLLEVVLAFGNYMNKGQRGNAFGFKISSLNKIADTKSSIDKNITLLHYLITIVEKKYPKVLRLHEELRDIPQAAKVNMTELEKEVNTLRSGLRAVETELDFQKSQVQQTGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFSKAVKHFGEDTDKMQPDEFFGIFDQFLQAVTEAKQENENMRRRKEEEERRARMEAQLKEQRERERKARKAKESGEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRIANQLADSGRERPITKLNF", "length": 1103, "header": "tr|A0A8V0YZD8-1|A0A1L1RZM2_CHICK Computationally mapped isoform of Dishevelled associated activator of morphosis 1 OS=Gallus gallus OX=9031 GN=DAAM1 PE=4 SV=1 CANONICAL=A0A1L1RZM2-1" }, "locus": { "chromosome": "5", "start_pos": 54374851, "end_pos": 54326741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041271.1", "url": "https://www.ensembl.org/id/ENSGALT00010041271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024162.1", "url": "https://www.ensembl.org/id/ENSGALP00010024162.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.", "journal": "Brain research. Developmental brain research", "date": "2004", "authors": "Kida Y, Shiraishi T, Ogura T", "evidence": [ { "database": "RefSeq", "id": "NP_001309297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001309297" } ], "reference": [ { "type": "PubMed", "id": "15464228", "url": "https://glygen.org/publication/PubMed/15464228" } ] } ], "pathway": [ { "id": "gga:423532", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423532", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A7V4-1", "protein_name": "Disheveled-associated activator of morphogenesis 1", "gene_name": "DAAM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCAAVPGGASPGAPGGPFPSSTPGSLLPPPPPPPLPGMPPPPPPPLPPGGPPPPPGPPPLGGIMPPPGAPLGLALKKKNIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDTLGSKLKVRELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSSALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVESKYPKVLNLNEELRDIPQAAKVNMTELDKEISTLRNGLKAVEMELEYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARLEAQLKEQRERERKMRKAKENSEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRITNQMTDSSRERPVTKLNF", "length": 1077 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MPI7-1", "protein_name": "Disheveled-associated activator of morphogenesis 1", "gene_name": "DAAM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVFAFAVSELRITRPSIIHQGSEQSLISQEIKQNSAMAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASLPGVSSPGAPGGPFPSSVPGSLLPPPPPPPLPGGMGPPPPPPLPPGGPPPPPGPPPLGGIMPPPGAPLGLALKKKNIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKVLDLEDLERTFSAYQRQQKEADAIDDTLGSKLKVRELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVEMELEYQKSQPSQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKENSEEGGEFDDLVSALRSGEVFDKDLSKLKRNRKRITNQMTDSSRERPVTKLNF", "length": 1104 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6GM04-1", "protein_name": "Disheveled-associated activator of morphogenesis 1", "gene_name": "Daam1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELNRRAVCASVPGGPSPGAPGGPFPPSGLGSLLPPPPPPLLSGGALPPPPPPLPPGGPPPPPGPPPLGGILPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNNSKQKEADAIDDALSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSSSEEVLRSSALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVTEAKQENENMRKRKEEEERRARLEAQLKEQRERERKMRKAKESSEESGEFDDLVSALRSGEVFDKDLSKLKRNRKRISNQVTDSSRERPITKLNF", "length": 1078 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSM5-1", "protein_name": "Dishevelled associated activator of morphogenesis, isoform D", "gene_name": "DAAM", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSMNQMSVLMDKINTTLQSCPIVCINEPDTHSANTEILQTSPESTLEKPKAAPSGGASTSVTSLNGSCIAINGGIGEGATATASAATSTAAGVTKITITSDNGNGNASTSTKAPTTGSSIDGYKNSSLVSITSLNSCSDLSQGSTATLPISSNSCSGNNVSRHPLSNNNSGSDTSSNNFQERFDFEHWKGLLSDYNCFHGLYRYWTQCSGRSSSANDNGGGSDQQQSQSNHENGLGSEAGSFYTHNILGYTFGYPFGLKEDLDGSGNCNSNCNGSSNTNGLGLRKWLSGNTSSNETPLQKHYRHQQKKKMPGFRGRRVWCGCFKDDEPPEICVVEGAFTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLLPYTGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAGLTGCNGAVSPPPAPPMLKAIPPPPPPMAPSMMPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGHTSPPRHGSLQREESGRERERTVRRQ", "length": 1463 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5RHJ3-1", "protein_name": "Disheveled-associated activator of morphogenesis 1b", "gene_name": "daam1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPRKRGGGGHGASFFFCCFQSSDHPEITYRLREDFALQTMEPALPIPSYDELDAMFSELVDELDLTEKHREAMFALPAEKKWQIYCSKKKEQEENKGATSWPEFYIDQLNSMAARKTLLALEKEEEEERNKTIESLKTALRTQPMRFVTRFIDLDGLTCILNFLKSMDYETTESQIHTSLIGCIKALMNNSQGRAHVLSHTESINIIAQSLATDNIKTKVAVLEIMGAVCLVPGGHKKILEAMLHYQKFACERTRFQTLLNDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGESSLEFRVHLRYEFLMLGIQPIIDKLRSHENSTLDRHLDYFEMLRNDDELTLSRRFEAIHIDTKSATQVFELVRKKLAHTDAYPHFMSVLHHCLLMPHKRSGNTVQYWLLLDRIVQQMVLQNDKGHDPDATPLENFNVKNVVRMLVNENEVKQWKEQAEKMRKDHHELQQKMEKKERECDAKTQEKEEMMQTLNKMKEKLEREMGEHKLVKQQVAEMTTRLHELSTRQIASVPGGPPVSGPLGGPLLPPPPPPPPGGMMPPPPPPPPCGAMMPPPPPPPPGGPPPPPGRPPFGSAPPPPGAPIGPSLKKKNIPQPSNPLKSFNWAKLSENKLEGTVWADVDDGRVFKILDLEDIEKTFSAYQRQQDFFMVNNNKQKETEDDTLSSKKVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQMLKFVPEKSDVDLLEEHKHELDRMAKADRFLYEMSRINHYQQRLQSLYFKKKFAERIAEIKPKVEALTKASKEVLHSRNFKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITILEKKYSKVMLFQEELKNVPEAAKVNMTELEKEINNLRSGLKSVESELDFQKKRPQEYGDKFVSVVSQFITVASFSFSDVEDSLCEAKELFIKTVKHFGEDADKMQPDEFFGIFDQFLQSFAEARQENENIRRRKEEEERRARMEAQLKEQREKERKARKAKENGEDDGGEFDDLVSALRSGEVFDKDLSKMKRNRKRINSQTSDSGRERPITKLNF", "length": 1079 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BPM0-1", "protein_name": "Disheveled-associated activator of morphogenesis 1", "gene_name": "Daam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELNRRAVCAAVPGGPSPGAPGGPFPSSGLGSLLPPPPPPLLSGGALPPPPPPLPPGGPPPPPGPPPLGGVLPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLDGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVAEAKQENENMRKRKEEEERRARLEAQLKEQRERERKVRKAKESSEESGEFDDLVSALRSGEVFDKDLSKLKRNRKRISNQVTDSSRERPITKLNF", "length": 1077 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4D1-1", "protein_name": "Disheveled-associated activator of morphogenesis 1", "gene_name": "DAAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGSLLPPPPPPPLPGGMLPPPPPPLPPGGPPPPPGPPPLGAIMPPPGAPMGLALKKKSIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKENSEESGEFDDLVSALRSGEVFDKDLSKLKRNRKRITNQMTDSSRERPITKLNF", "length": 1078 }, "evidence": [ { "id": "A0A1L1RZM2", "url": "https://omabrowser.org/oma/group/A0A1L1RZM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZM2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U652-1", "uniprot_ac": "A0A3Q2U652", "uniprot_id": "A0A3Q2U652_CHICK", "mass": { "chemical_mass": 49152.0, "monoisotopic_mass": 49152.0 }, "refseq": { "ac": "XP_422591", "name": "divergent protein kinase domain 2A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422591" }, "gene_names": [ { "name": "DIPK2A", "type": "recommended", "evidence": [ { "id": "A0A3Q2U652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ] }, { "name": "DIPK2A", "type": "synonym", "evidence": [ { "id": "XP_422591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422591" } ] } ], "protein_names": [ { "name": "Divergent protein kinase domain 2A", "type": "synonym", "evidence": [ { "id": "A0A3Q2U652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652/entry#names_and_taxonomy" } ] }, { "name": "divergent protein kinase domain 2A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422591" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_422591.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422591" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIPK2A", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652", "locus": { "chromosome": "9", "start_pos": 10596398, "end_pos": 10582277, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015963", "url": "https://www.ensembl.org/id/ENSGALG00010015963" } ] } } ], "crossref": [ { "id": "A0A3Q2U652", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U652", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002347", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002347", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424771", "url": "https://www.ncbi.nlm.nih.gov/gene/424771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424771", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424771", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWAACYI", "url": "https://omabrowser.org/oma/group/LWAACYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U652", "url": "https://www.orthodb.org/?gene=A0A3Q2U652", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUG0", "url": "https://www.orthodb.org/?gene=A0A8V0YUG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUG6", "url": "https://www.orthodb.org/?gene=A0A8V0YUG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32073:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32073:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U652-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLVSLKLGRLYRYVKLAVLGSLAAALVLNTHSLLASLQRNELAERRFLQLNKCPACWGTSWCRKFLNGQLRLESWGRLRLFDFFNVKNVYFARYGEPREGSRRVVLKRLGSAQELADIDAKICRRATGRGRCDLLQALHATEFASLNGDVRLLTPDAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLITLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPADIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVR", "length": 429, "header": "tr|A0A3Q2U652-1|A0A3Q2U652_CHICK Isoform 1 of Divergent protein kinase domain 2A OS=Gallus gallus OX=9031 GN=DIPK2A PE=3 SV=1 CANONICAL=A0A3Q2U652-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U652-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652/entry", "sequence": { "sequence": "MLRLVSLKLGRLYRYVKLAVLGSLAAALVLNTHSLLASLQRNELAERRFLQLNKCPACWGTSWCRKFLNGQLRLESWGRLRLFDFFNVKNVYFARYGEPREGSRRVVLKRLGSAQELADIDAKICRRATGRGRCDLLQALHATEFASLNGDVRLLTPDAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLITLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPADIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVR", "length": 429, "header": "tr|A0A3Q2U652-1|A0A3Q2U652_CHICK Isoform 1 of Divergent protein kinase domain 2A OS=Gallus gallus OX=9031 GN=DIPK2A PE=3 SV=1 CANONICAL=A0A3Q2U652-1" }, "locus": { "chromosome": "9", "start_pos": 10593743, "end_pos": 10582461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038471.1", "url": "https://www.ensembl.org/id/ENSGALT00010038471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022255.1", "url": "https://www.ensembl.org/id/ENSGALP00010022255.1" } ] } }, { "isoform_ac": "A0A8V0YUG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG0/entry", "sequence": { "sequence": "MLRLVSLKLGRLYRYVKLAVLGSLAAALVLNTHSLLASLQRNELAERRFLQLNKCPACWGTSWCRKFLNGQLRLESWGRLRLFDFFNVKNVYFARYGEPREGSRRVVLKRLGSAQELADIDAKICRRATGRGRCDLLQALHATEFASLNGDVRLLTPDAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLITLAFNPEPLVLQINLKTGMYGMKANLMTVIKKLVCPSQKRFFVLVSLWTTIIMLFVRTFYRDMPRGVALPEDYFMTPQLTLPKMAGLRPCWMSVPTQRSDMADSKQQRNCVNTLHNSVTM", "length": 326, "header": "tr|A0A8V0YUG0-1|A0A3Q2U652_CHICK Computationally mapped isoform of Divergent protein kinase domain 2A OS=Gallus gallus OX=9031 GN=DIPK2A PE=3 SV=1 CANONICAL=A0A3Q2U652-1" }, "locus": { "chromosome": "9", "start_pos": 10593738, "end_pos": 10582461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038462.1", "url": "https://www.ensembl.org/id/ENSGALT00010038462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022248.1", "url": "https://www.ensembl.org/id/ENSGALP00010022248.1" } ] } }, { "isoform_ac": "A0A8V0YUG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG6/entry", "sequence": { "sequence": "MLRLVSLKLGRLYRYVKLAVLGSLAAALVLNTHSLLASLQRNELAERRFLQLNKCPACWGTSWCRKFLNGQLRLESWGRLRLFDFFNVKNVYFARYGEPREGSRRVVLKRLGSAQELADIDAKICRRATGRGRCDLLQALHATEFASLNGDVRLLTPDAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLITLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPADIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVSSAIGDFTSCNYCTKFLSLIPVHSRDCSSENHGMSKPSFSRHSL", "length": 472, "header": "tr|A0A8V0YUG6-1|A0A3Q2U652_CHICK Computationally mapped isoform of Divergent protein kinase domain 2A OS=Gallus gallus OX=9031 GN=DIPK2A PE=3 SV=1 CANONICAL=A0A3Q2U652-1" }, "locus": { "chromosome": "9", "start_pos": 10594536, "end_pos": 10582461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038469.1", "url": "https://www.ensembl.org/id/ENSGALT00010038469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022253.1", "url": "https://www.ensembl.org/id/ENSGALP00010022253.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424771", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424771", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BRY2-1", "protein_name": "Divergent protein kinase domain 2A", "gene_name": "DIPK2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWRLVPPKLGRLSRSLKLAALGSLLVLMVLHSPSLLASWQRNELADRRFLQLNKCPACFGTSWCRRFLNGQVVFEAWGRLRLLDFLNVKNVYFAQYGEPREGGRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARATVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVR", "length": 430 }, "evidence": [ { "id": "A0A3Q2U652", "url": "https://omabrowser.org/oma/group/A0A3Q2U652/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BNC4-1", "protein_name": "Divergent protein kinase domain 2A", "gene_name": "DIPK2A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWRLVPPKLGRLSRSLKLAALGSLLVLMVLHSPSLLASWQRNELADRRFLQLNKCPACFGTSWCRRFLNGQVVFEAWGRLRLLDFLNVKNVYFAQYGEPREGGRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARATVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVR", "length": 430 }, "evidence": [ { "id": "A0A3Q2U652", "url": "https://omabrowser.org/oma/group/A0A3Q2U652/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3USZ8-1", "protein_name": "Divergent protein kinase domain 2A", "gene_name": "Dipk2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRLVPLKLGRLSRALKLAALGSLLVLMLLHSPSLLASWQRNELADRRFLQLNKCPACFGTSWCRRFLNGQVGFETWGRLRLLDFLNVKNVYFAQYGEPREGGRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARVTVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLDECTNPKKRYGRFQAAKELRGYLAQLSHNVR", "length": 430 }, "evidence": [ { "id": "A0A3Q2U652", "url": "https://omabrowser.org/oma/group/A0A3Q2U652/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDZ4-1", "protein_name": "Divergent protein kinase domain 2A", "gene_name": "DIPK2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWRLVPPKLGRLSRSLKLAALGSLLVLMVLHSPSLLASWQRNELTDRRFLQLNKCPACFGTSWCRRFLNGQVVFEAWGRLRLLDFLNVKNVYFAQYGEPREGGRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEAVEGWSDLVHCPSQRLLDRLVRRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVLQSFPSDEGWPFAKYLGACGRMVAVNYVGEELWSYFNAPWEKRVDLAWQLMEIAEQLTNNDFEFALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKEACLSFSKEILCARATVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLDECANPKKRYGRFQAAKELREYLAQLSNNVR", "length": 430 }, "evidence": [ { "id": "A0A3Q2U652", "url": "https://omabrowser.org/oma/group/A0A3Q2U652/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" }, { "name": "negative regulation of smooth muscle cell apoptotic process", "id": "GO:0034392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034392", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" }, { "name": "cardiac muscle cell proliferation", "id": "GO:0060038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060038", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U652", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U652" }, { "id": "PF12260", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM69 protein-kinase", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 404, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UB91-1", "uniprot_ac": "A0A3Q2UB91", "uniprot_id": "A0A3Q2UB91_CHICK", "mass": { "chemical_mass": 82861.0, "monoisotopic_mass": 82861.0 }, "refseq": { "ac": "XP_417479", "name": "engulfment and cell motility protein 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417479" }, "gene_names": [ { "name": "ELMO2", "type": "recommended", "evidence": [ { "id": "A0A3Q2UB91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ] }, { "name": "ELMO2", "type": "synonym", "evidence": [ { "id": "XP_417479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417479" } ] } ], "protein_names": [ { "name": "Engulfment and cell motility 2", "type": "synonym", "evidence": [ { "id": "A0A3Q2UB91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91/entry#names_and_taxonomy" } ] }, { "name": "engulfment and cell motility protein 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_417479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417479" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_417479.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417479" } ] }, { "annotation": "Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ4#function" }, { "database": "UniProtKB", "id": "ARBA00024863", "url": "https://www.uniprot.org/uniprotkb/ARBA00024863#function" }, { "database": "UniProtKB", "id": "A0A8V0Z1H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H3#function" }, { "database": "UniProtKB", "id": "E1C122", "url": "https://www.uniprot.org/uniprotkb/E1C122#function" }, { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ELMO2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91", "locus": { "chromosome": "20", "start_pos": 11074292, "end_pos": 11092792, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016182", "url": "https://www.ensembl.org/id/ENSGALG00010016182" } ] } } ], "crossref": [ { "id": "A0A3Q2UB91", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UB91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007246", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007246", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419307", "url": "https://www.ncbi.nlm.nih.gov/gene/419307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419307", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNHKMLH", "url": "https://omabrowser.org/oma/group/LNHKMLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UB91", "url": "https://www.orthodb.org/?gene=A0A3Q2UB91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUQ4", "url": "https://www.orthodb.org/?gene=A0A8V0YUQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1H3", "url": "https://www.orthodb.org/?gene=A0A8V0Z1H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C122", "url": "https://www.orthodb.org/?gene=E1C122", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8849471", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C122", "url": "https://www.uniprot.org/uniprotkb/E1C122", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C122-1", "url": "https://www.uniprot.org/uniprotkb/E1C122-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPSDIVKVAVEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRCDIKNGTILQLAVSPSRAARQLMERIQSHSMEVRLDAMKELAKLSADVTFATEFINMEGITVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQTLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQEMANSFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDSNTIPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKFHQDTYIRIVLENSSREDKHECPFGRSAIELTRMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFAICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLEDNAQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLNALLGKDMSSELTRSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 720, "header": "tr|A0A3Q2UB91-1|A0A3Q2UB91_CHICK Isoform 1 of Engulfment and cell motility 2 OS=Gallus gallus OX=9031 GN=ELMO2 PE=1 SV=1 CANONICAL=A0A3Q2UB91-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91/entry", "sequence": { "sequence": "MPPPSDIVKVAVEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRCDIKNGTILQLAVSPSRAARQLMERIQSHSMEVRLDAMKELAKLSADVTFATEFINMEGITVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQTLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQEMANSFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDSNTIPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKFHQDTYIRIVLENSSREDKHECPFGRSAIELTRMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFAICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLEDNAQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLNALLGKDMSSELTRSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 720, "header": "tr|A0A3Q2UB91-1|A0A3Q2UB91_CHICK Isoform 1 of Engulfment and cell motility 2 OS=Gallus gallus OX=9031 GN=ELMO2 PE=1 SV=1 CANONICAL=A0A3Q2UB91-1" }, "locus": { "chromosome": "20", "start_pos": 11086987, "end_pos": 11074413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038892.1", "url": "https://www.ensembl.org/id/ENSGALT00010038892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022477.1", "url": "https://www.ensembl.org/id/ENSGALP00010022477.1" } ] } }, { "isoform_ac": "A0A8V0YUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ4/entry", "sequence": { "sequence": "MPPPSDIVKVAVEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRCDIKNGTILQLAVSPSRAARQLMERIQSHSMEVRLDAMKELAKLSADVTFATEFINMEGITVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQTLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKLLNPLDLPITEMANSFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDSNTIPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKFHQDTYIRIVLENSSREDKHECPFGRSAIELTRMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFAICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQVPERFWYCRLALNHKVLHYGDLEDNAQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLNALLGKDMSSELTRSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 734, "header": "tr|A0A8V0YUQ4-1|A0A3Q2UB91_CHICK Computationally mapped isoform of Engulfment and cell motility 2 OS=Gallus gallus OX=9031 GN=ELMO2 PE=1 SV=1 CANONICAL=A0A3Q2UB91-1" }, "locus": { "chromosome": "20", "start_pos": 11086987, "end_pos": 11074413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038886.1", "url": "https://www.ensembl.org/id/ENSGALT00010038886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022475.1", "url": "https://www.ensembl.org/id/ENSGALP00010022475.1" } ] } }, { "isoform_ac": "A0A8V0Z1H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H3/entry", "sequence": { "sequence": "MPPPSDIVKVAVEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRCDIKNGTILQLAVSPSRAARQLMERIQSHSMEVRLDAMKELAKLSADVTFATEFINMEGITVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQTLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQEMANSFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDSNTIPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKFHQDTYIRIVLENSSREDKHECPFGRSAIELTRMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFAICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLEDNAQGEVTFESLQEKNEAAAAGLGEHPDPRGAAAHPQGAEQLRLRVPLRLTGAAARPGGPSRCAAVPGLLRRRLAAVRLLYEFE", "length": 669, "header": "tr|A0A8V0Z1H3-1|A0A3Q2UB91_CHICK Computationally mapped isoform of Engulfment and cell motility 2 OS=Gallus gallus OX=9031 GN=ELMO2 PE=1 SV=1 CANONICAL=A0A3Q2UB91-1" }, "locus": { "chromosome": "20", "start_pos": 11086987, "end_pos": 11074309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038896.1", "url": "https://www.ensembl.org/id/ENSGALT00010038896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022479.1", "url": "https://www.ensembl.org/id/ENSGALP00010022479.1" } ] } }, { "isoform_ac": "E1C122-1", "url": "https://www.uniprot.org/uniprotkb/E1C122/entry", "sequence": { "sequence": "MPPPSDIVKVAVEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRCDIKNGTILQLAVSPSRAARQLMERIQSHSMEVRLDAMKELAKLSADVTFATEFINMEGITVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQTLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKLLNPLDLPITEMANSFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDSNTIPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKFHQDTYIRIVLENSSREDKHECPFGRSAIELTRMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFAICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLEDNAQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLNALLGKDMSSELTRSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 732, "header": "tr|E1C122-1|A0A3Q2UB91_CHICK Computationally mapped isoform of Engulfment and cell motility 2 OS=Gallus gallus OX=9031 GN=ELMO2 PE=1 SV=4 CANONICAL=A0A3Q2UB91-1" }, "locus": { "chromosome": "20", "start_pos": 11086987, "end_pos": 11074413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038881.1", "url": "https://www.ensembl.org/id/ENSGALT00010038881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022471.1", "url": "https://www.ensembl.org/id/ENSGALP00010022471.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419307", "resource": "KEGG Pathway" }, { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-8849471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849471", "resource": "Reactome", "description": "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKS3-1", "protein_name": "Engulfment and cell motility 2", "gene_name": "ELMO2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRNDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNVPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 720 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6G6K9-1", "protein_name": "Engulfment and cell motility 2", "gene_name": "Elmo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQQLSPEVGPLGTMPPPSDIVKVAIEWPGANAQLLEIDQKRPLASVIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRSDIKNGTILQLAISPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDLVSITFIKQIAGYVSQPMADVSVLQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 734 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MUZ4-1", "protein_name": "Engulfment and cell motility 2", "gene_name": "ELMO2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKHLNPLDLPVTDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDADSDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 732 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H8U1-1", "protein_name": "Engulfment and cell motility protein 2 isoform X1", "gene_name": "Elmo2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEMDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRNDIKNGTILQLAISPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGILVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNVPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 720 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BHL5-1", "protein_name": "Engulfment and cell motility protein 2", "gene_name": "Elmo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRNDIKNGTILQLAVSPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSVTFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKHLNPLDLPVTDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNVPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 732 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JJ3-1", "protein_name": "Engulfment and cell motility protein 2", "gene_name": "ELMO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 720 }, "evidence": [ { "id": "A0A3Q2UB91", "url": "https://omabrowser.org/oma/group/A0A3Q2UB91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "cell motility", "id": "GO:0048870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048870", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "regulation of vasculogenesis", "id": "GO:2001212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001212", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 395, "end_pos": 397 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UG55-1", "uniprot_ac": "A0A3Q2UG55", "uniprot_id": "A0A3Q2UG55_CHICK", "mass": { "chemical_mass": 22761.0, "monoisotopic_mass": 22761.0 }, "refseq": { "ac": "NP_001376417", "name": "ras-related protein Rab-9B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376417" }, "gene_names": [ { "name": "RAB9B", "type": "recommended", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "name": "RAB9B", "type": "synonym", "evidence": [ { "id": "NP_001376417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376417" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-9B", "type": "synonym", "evidence": [ { "id": "NP_001376417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376417" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01103108.1, SRR13267656.9546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Dec 28, 2020 this sequence version replaced XP_420182.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB9B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55", "locus": { "chromosome": "4", "start_pos": 1952744, "end_pos": 1944898, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016473", "url": "https://www.ensembl.org/id/ENSGALG00010016473" } ] } } ], "crossref": [ { "id": "ENSGALG00000004918", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422187", "url": "https://www.ncbi.nlm.nih.gov/gene/422187", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422187", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422187", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKAWCME", "url": "https://omabrowser.org/oma/group/AKAWCME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UG55", "url": "https://www.orthodb.org/?gene=A0A3Q2UG55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW18", "url": "https://www.orthodb.org/?gene=A0A8V0YW18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWI0", "url": "https://www.orthodb.org/?gene=A0A8V0YWI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9706019", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLSNWQKEFVYYADVKDPERFPFVVLGNKIDKLERQVSTEEAQAWCMENGNYPYLETSAKDDTNVAVAFEEAVRQVLAVEEQLEHCMLGHTIDLHSSSKSGSSCC", "length": 201, "header": "tr|A0A3Q2UG55-1|A0A3Q2UG55_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB9B PE=3 SV=1 CANONICAL=A0A3Q2UG55-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55/entry", "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLSNWQKEFVYYADVKDPERFPFVVLGNKIDKLERQVSTEEAQAWCMENGNYPYLETSAKDDTNVAVAFEEAVRQVLAVEEQLEHCMLGHTIDLHSSSKSGSSCC", "length": 201, "header": "tr|A0A3Q2UG55-1|A0A3Q2UG55_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB9B PE=3 SV=1 CANONICAL=A0A3Q2UG55-1" }, "locus": { "chromosome": "4", "start_pos": 1949569, "end_pos": 1948967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039724.1", "url": "https://www.ensembl.org/id/ENSGALT00010039724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022981.1", "url": "https://www.ensembl.org/id/ENSGALP00010022981.1" } ] } }, { "isoform_ac": "A0A8V0YW18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW18/entry", "sequence": { "sequence": "MRVRRACAGRAGTCPRRVGSGRWAAAAAGGRLPRSRGRPSCCNEWEVLALKGHSARRWRRREELPHEPIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLSNWQKEFVYYADVKDPERFPFVVLGNKIDKLERQVSTEEAQAWCMENGNYPYLETSAKDDTNVAVAFEEAVRQVLAVEEQLEHCMLGHTIDLHSSSKSGSSCC", "length": 210, "header": "tr|A0A8V0YW18-1|A0A3Q2UG55_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB9B PE=3 SV=1 CANONICAL=A0A3Q2UG55-1" }, "locus": { "chromosome": "4", "start_pos": 1949569, "end_pos": 1946502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039693.1", "url": "https://www.ensembl.org/id/ENSGALT00010039693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022952.1", "url": "https://www.ensembl.org/id/ENSGALP00010022952.1" } ] } }, { "isoform_ac": "A0A8V0YWI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWI0/entry", "sequence": { "sequence": "MCTYLQWLSCWRKAFPAQSWRQKCPIARAGCLGPVAGRPAAMSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLSNWQKEFVYYADVKDPERFPFVVLGNKIDKLERQVSTEEAQAWCMENGNYPYLETSAKDDTNVAVAFEEAVRQVLAVEEQLEHCMLGHTIDLHSSSKSGSSCC", "length": 242, "header": "tr|A0A8V0YWI0-1|A0A3Q2UG55_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB9B PE=3 SV=1 CANONICAL=A0A3Q2UG55-1" }, "locus": { "chromosome": "4", "start_pos": 1949569, "end_pos": 1945110, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039729.1", "url": "https://www.ensembl.org/id/ENSGALT00010039729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022985.1", "url": "https://www.ensembl.org/id/ENSGALP00010022985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422187", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" }, { "id": "R-GGA-9706019", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "resource": "Reactome", "description": "RHOBTB3 ATPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W519-1", "protein_name": "small monomeric GTPase", "gene_name": "RAB9B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKEDRQVTTEEAQAWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTVDLNSGSKAGSSCC", "length": 201 }, "evidence": [ { "id": "A0A3Q2UG55", "url": "https://omabrowser.org/oma/group/A0A3Q2UG55/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZP15-1", "protein_name": "small monomeric GTPase", "gene_name": "Rab9b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKEDRQVTTEEAQAWCMENGNYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKASSSCC", "length": 201 }, "evidence": [ { "id": "A0A3Q2UG55", "url": "https://omabrowser.org/oma/group/A0A3Q2UG55/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHH2-1", "protein_name": "Ras-related protein Rab-9B", "gene_name": "Rab9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPDHFPFVVLGNKVDKEDRQVTTEEAQAWCMENGNYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKASSSCC", "length": 201 }, "evidence": [ { "id": "A0A3Q2UG55", "url": "https://omabrowser.org/oma/group/A0A3Q2UG55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP90-1", "protein_name": "Ras-related protein Rab-9B", "gene_name": "RAB9B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKEDRQVTTEEAQTWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKAGSSCC", "length": 201 }, "evidence": [ { "id": "A0A3Q2UG55", "url": "https://omabrowser.org/oma/group/A0A3Q2UG55/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UG55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, secretory granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1", "A0A8V0X882-1", "Q5ZHW4-1", "Q1KME6-1", "A0A8V0Z0I1-1", "A0A8V0Z8U4-1", "A0A8V0Y298-1", "A0A8V0Y2H3-1", "A0A8V0YFC8-1" ], "evidence": [ { "id": "R-GGA-6798743", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798743" } ] }, { "id": "R-GGA-6814670", "name": "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "transport vesicle", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1" ], "evidence": [ { "id": "R-GGA-6814670", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814670" } ] }, { "id": "R-GGA-6814671", "name": "Fusion of late-endosome derived vesicles at the TGN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1" ], "evidence": [ { "id": "R-GGA-6814671", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814671" } ] }, { "id": "R-GGA-6814675", "name": "RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1" ], "evidence": [ { "id": "R-GGA-6814675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814675" } ] }, { "id": "R-GGA-8876191", "name": "RAB9 GEFs exchange GTP for GDP on RAB9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1" ], "evidence": [ { "id": "R-GGA-8876191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876191" } ] }, { "id": "R-GGA-9706390", "name": "RHOBTB3 binds interacting proteins at trans-Golgi network", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, trans-Golgi network membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UG55-1" ], "evidence": [ { "id": "R-GGA-9706390", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706390" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X882", "gene_name": "MME", "activity": [ { "ec_number": "3.4.24.11", "activity": "Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1'.", "evidence": [ { "id": "A0A8V0X882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X882" } ] }, { "ec_number": "3.4.24.11", "activity": "", "evidence": [ { "id": "A0A8V0X882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X882" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y298", "gene_name": "B4GALT1", "activity": [ { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] }, { "ec_number": "2.4.1.90", "activity": "", "evidence": [ { "id": "A0A8V0Y298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y298" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": "A0A8V0Y4A4", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": 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"evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ] }, { "uniprot_ac": "A0A8V0YDX6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJA9-1", "uniprot_ac": "Q5ZJA9", "uniprot_id": "BORC5_CHICK", "mass": { "chemical_mass": 20934.0, "monoisotopic_mass": 20934.0 }, "refseq": { "ac": "NP_001026528", "name": "BLOC-1-related complex subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" }, "gene_names": [ { "name": "BORCS5", "type": "recommended", "evidence": [ { "id": "Q5ZJA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ] }, { "name": "BORCS5", "type": "synonym", "evidence": [ { "id": "NP_001026528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] }, { "name": "LOH12CR1", "type": "synonym", "evidence": [ { "id": "NP_001026528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] }, { "name": "RCJMB04_19j2", "type": "synonym", "evidence": [ { "id": "Q5ZJA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ] } ], "protein_names": [ { "name": "BLOC-1-related complex subunit 5", "type": "recommended", "evidence": [ { "id": "Q5ZJA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9/entry#names_and_taxonomy" } ] }, { "name": "BLOC-1-related complex subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001026528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] }, { "name": "loss of heterozygosity 12 chromosomal region 1 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001026528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] }, { "name": "loss of heterozygosity, 12, chromosomal region 1", "type": "synonym", "evidence": [ { "id": "NP_001026528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720525.1, HAEK01044188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Aug 8, 2005 this sequence version replaced XP_423787.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528" } ] }, { "annotation": "As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9#function" }, { "database": "UniProtKB", "id": "Q969J3", "url": "https://www.uniprot.org/uniprotkb/Q969J3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BORCS5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9", "locus": { "chromosome": "1", "start_pos": 71950870, "end_pos": 71888800, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021652", "url": "https://www.ensembl.org/id/ENSGALG00010021652" } ] } } ], "crossref": [ { "id": "Q5ZJA9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040393", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040393", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22789", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22789", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426116", "url": "https://www.ncbi.nlm.nih.gov/gene/426116", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426116", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426116", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGRPHDP", "url": "https://omabrowser.org/oma/group/EGRPHDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P955", "url": "https://www.orthodb.org/?gene=A0A1D5P955", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL33", "url": "https://www.orthodb.org/?gene=A0A8V0ZL33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJA9", "url": "https://www.orthodb.org/?gene=Q5ZJA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJA9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJA9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P955", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P955", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P955-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P955-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJA9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVNGSHASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS", "length": 185, "header": "sp|Q5ZJA9-1|BORC5_CHICK Isoform 1 of BLOC-1-related complex subunit 5 OS=Gallus gallus OX=9031 GN=BORCS5 PE=2 SV=1 CANONICAL=Q5ZJA9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P955-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P955/entry", "sequence": { "sequence": "MGAEQSAEAESRPGEPSASASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS", "length": 196, "header": "tr|A0A1D5P955-1|BORC5_CHICK Computationally mapped isoform of BLOC-1-related complex subunit 5 OS=Gallus gallus OX=9031 GN=BORCS5 PE=2 SV=1 CANONICAL=Q5ZJA9-1" }, "locus": { "chromosome": "1", "start_pos": 71947152, "end_pos": 71889479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052599.1", "url": "https://www.ensembl.org/id/ENSGALT00010052599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031505.1", "url": "https://www.ensembl.org/id/ENSGALP00010031505.1" } ] } }, { "isoform_ac": "A0A8V0ZL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL33/entry", "sequence": { "sequence": "MLQLSKASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS", "length": 183, "header": "tr|A0A8V0ZL33-1|A0A8V0ZL33_CHICK Computationally mapped isoform of BLOC-1-related complex subunit 5 OS=Gallus gallus OX=9031 GN=BORCS5 PE=1 SV=1 CANONICAL=Q5ZJA9-1" }, "locus": { "chromosome": "1", "start_pos": 71947152, "end_pos": 71888940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052604.1", "url": "https://www.ensembl.org/id/ENSGALT00010052604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031510.1", "url": "https://www.ensembl.org/id/ENSGALP00010031510.1" } ] } }, { "isoform_ac": "Q5ZJA9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9/entry#Q5ZJA9-1", "sequence": { "sequence": "MAGVNGSHASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS", "length": 185, "header": "sp|Q5ZJA9-1|BORC5_CHICK Isoform 1 of BLOC-1-related complex subunit 5 OS=Gallus gallus OX=9031 GN=BORCS5 PE=2 SV=1 CANONICAL=Q5ZJA9-1" }, "locus": { "chromosome": "1", "start_pos": 71947152, "end_pos": 71889766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052595.1", "url": "https://www.ensembl.org/id/ENSGALT00010052595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031501.1", "url": "https://www.ensembl.org/id/ENSGALP00010031501.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426116", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426116", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1H257-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "Borcs5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSEQSAEAESRPGDLNASVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNARLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFCFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPEAERLEPFSMRPERERH", "length": 195 }, "evidence": [ { "id": "Q5ZJA9", "url": "https://omabrowser.org/oma/group/Q5ZJA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08DP2-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLERLNSLLPEAERLEPFSVKPDRELRL", "length": 196 }, "evidence": [ { "id": "Q5ZJA9", "url": "https://omabrowser.org/oma/group/Q5ZJA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIX8-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "borcs5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGAEQSGDADHKHSDFSASVVPSPAKHRAKMDDIVVVAQGTQSLRNIHNDPDVIKLQEIPTFQPLLKGVLSGQTSPSTVCLEKLDSAQVLQLCVRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVEALFSIMQERQKRYAKYAEQIQKVNEMSMILRRIQMGIDQTVPLMERLNNMLPESLFWMLPMEHITFALDCLSYAWIRCFLA", "length": 207 }, "evidence": [ { "id": "Q5ZJA9", "url": "https://omabrowser.org/oma/group/Q5ZJA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q969J3-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPDRELRL", "length": 196 }, "evidence": [ { "id": "Q5ZJA9", "url": "https://omabrowser.org/oma/group/Q5ZJA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D920-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "Borcs5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSEQSAEAESRPGDLNASVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFCFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPEAERLEPFSMKPERERH", "length": 195 }, "evidence": [ { "id": "Q5ZJA9", "url": "https://omabrowser.org/oma/group/Q5ZJA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "cytoplasmic side of lysosomal membrane", "id": "GO:0098574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098574", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "BORC complex", "id": "GO:0099078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099078", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "plus-end kinesin complex", "id": "GO:0005873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005873", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "organelle transport along microtubule", "id": "GO:0072384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072384", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" }, { "name": "positive regulation of anterograde synaptic vesicle transport", "id": "GO:1903744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903744", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJA9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 185, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJA9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJA9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TZK0-1", "uniprot_ac": "A0A3Q2TZK0", "uniprot_id": "A0A3Q2TZK0_CHICK", "mass": { "chemical_mass": 43529.0, "monoisotopic_mass": 43529.0 }, "refseq": { "ac": "NP_001001747", "name": "alpha-2,8-sialyltransferase 8E isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" }, "gene_names": [ { "name": "ST8SIA5", "type": "recommended", "evidence": [ { "id": "A0A3Q2TZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ] }, { "name": "SIAT8E", "type": "synonym", "evidence": [ { "id": "NP_001001747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] }, { "name": "ST8SIA5", "type": "synonym", "evidence": [ { "id": "NP_001001747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] } ], "protein_names": [ { "name": "Alpha-2,8-sialyltransferase 8E", "type": "recommended", "evidence": [ { "id": "A0A3Q2TZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase 8E", "type": "synonym", "evidence": [ { "id": "A0A3Q2TZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase St8Sia V", "type": "synonym", "evidence": [ { "id": "A0A3Q2TZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0/entry#names_and_taxonomy" } ] }, { "name": "alpha-2,8-sialyltransferase 8E isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001001747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] }, { "name": "alpha-2,8-sialyltransferase 8E", "type": "synonym", "evidence": [ { "id": "NP_001001747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] }, { "name": "alpha-2,8-syalyltransferase ST8Sia-V", "type": "synonym", "evidence": [ { "id": "NP_001001747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: AJ704564.1, SRR12888497.624882.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000086.1. On or before Oct 17, 2021 this sequence version replaced XP_040511409.1, NP_001001747.1. Sequence Note:.", "evidence": [ { "database": "RefSeq", "id": "NP_001001747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747" } ] }, { "annotation": "Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PIR8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIR8#function" }, { "database": "UniProtKB", "id": "ARBA00056957", "url": "https://www.uniprot.org/uniprotkb/ARBA00056957#function" }, { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0#function" }, { "database": "UniProtKB", "id": "A0A8V0YC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC93#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST8SIA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0", "locus": { "chromosome": "Z", "start_pos": 2210183, "end_pos": 2153797, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009858", "url": "https://www.ensembl.org/id/ENSGALG00010009858" } ] } } ], "crossref": [ { "id": "A0A3Q2TZK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TZK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035927", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035927", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414797", "url": "https://www.ncbi.nlm.nih.gov/gene/414797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:414797", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFICAFG", "url": "https://omabrowser.org/oma/group/MFICAFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PIR8", "url": "https://www.orthodb.org/?gene=A0A1D5PIR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TZK0", "url": "https://www.orthodb.org/?gene=A0A3Q2TZK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC93", "url": "https://www.orthodb.org/?gene=A0A8V0YC93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001001747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "47592", "url": "https://www.rhea-db.org/rhea/47592", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PIR8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGYTDPSSGRDLLGNRTLFFIFICAFAVVTLLQQILYGRNYLKRYFEFYEGPLEYNSTKCLELRQDIIAVKVLSMVKQTELFDRWKSLQMCKWEMNVTEANILKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIFHINQEIFKMFPKDMPYHRSQFKKCAVVGNGGILKNSRCGREIDSADFVFRCNLPPISEKYLTDVGVKTDVVTVNPSIITERFHKLEKWRKPFYDVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESQQAVYYFHPQYLINVSRYWLGQGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGIFITHHYYDNVKPRPGFHAMPSEIFNFLHMHSKGILRVHTGTCGCC", "length": 376, "header": "tr|A0A3Q2TZK0-1|A0A3Q2TZK0_CHICK Isoform 1 of Alpha-2,8-sialyltransferase 8E OS=Gallus gallus OX=9031 GN=ST8SIA5 PE=3 SV=1 CANONICAL=A0A3Q2TZK0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIR8/entry", "sequence": { "sequence": "MGYTDPSSGRDLLGNRTLFFIFICAFAVVTLLQQILYGRNYLKRGLQFSWQNGEELANWTGTFNFTDDGAVKSGSDTGTRYFEFYEGPLEYNSTKCLELRQDIIAVKVLSMVKQTELFDRWKSLQMCKWEMNVTEANILKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIFHINQEIFKMFPKDMPYHRSQFKKCAVVGNGGILKNSRCGREIDSADFVFRCNLPPISEKYLTDVGVKTDVVTVNPSIITERFHKLEKWRKPFYDVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESQQAVYYFHPQYLINVSRYWLGQGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGIFITHHYYDNVKPRPGFHAMPSEIFNFLHMHSKGILRVHTGTCGCC", "length": 412, "header": "tr|A0A1D5PIR8-1|A0A3Q2TZK0_CHICK Computationally mapped isoform of Alpha-2,8-sialyltransferase 8E OS=Gallus gallus OX=9031 GN=ST8SIA5 PE=3 SV=1 CANONICAL=A0A3Q2TZK0-1" }, "locus": { "chromosome": "Z", "start_pos": 2207869, "end_pos": 2179049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023541.1", "url": "https://www.ensembl.org/id/ENSGALT00010023541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013563.1", "url": "https://www.ensembl.org/id/ENSGALP00010013563.1" } ] } }, { "isoform_ac": "A0A3Q2TZK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0/entry", "sequence": { "sequence": "MGYTDPSSGRDLLGNRTLFFIFICAFAVVTLLQQILYGRNYLKRYFEFYEGPLEYNSTKCLELRQDIIAVKVLSMVKQTELFDRWKSLQMCKWEMNVTEANILKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIFHINQEIFKMFPKDMPYHRSQFKKCAVVGNGGILKNSRCGREIDSADFVFRCNLPPISEKYLTDVGVKTDVVTVNPSIITERFHKLEKWRKPFYDVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESQQAVYYFHPQYLINVSRYWLGQGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGIFITHHYYDNVKPRPGFHAMPSEIFNFLHMHSKGILRVHTGTCGCC", "length": 376, "header": "tr|A0A3Q2TZK0-1|A0A3Q2TZK0_CHICK Isoform 1 of Alpha-2,8-sialyltransferase 8E OS=Gallus gallus OX=9031 GN=ST8SIA5 PE=3 SV=1 CANONICAL=A0A3Q2TZK0-1" }, "locus": { "chromosome": "Z", "start_pos": 2207869, "end_pos": 2179049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023546.1", "url": "https://www.ensembl.org/id/ENSGALT00010023546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013564.1", "url": "https://www.ensembl.org/id/ENSGALP00010013564.1" } ] } }, { "isoform_ac": "A0A8V0YC93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC93/entry", "sequence": { "sequence": "MSRGLQFSWQNGEELANWTGTFNFTDDGAVKSGSDTGTRYFEFYEGPLEYNSTKCLELRQDIIAVKVLSMVKQTELFDRWKSLQMCKWEMNVTEANILKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIFHINQEIFKMFPKDMPYHRSQFKKCAVVGNGGILKNSRCGREIDSADFVFRCNLPPISEKYLTDVGVKTDVVTVNPSIITERFHKLEKWRKPFYDVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESQQAVYYFHPQYLINVSRYWLGQGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGIFITHHYYDNVKPRPGFHAMPSEIFNFLHMHSKGILRVHTGTCGCC", "length": 371, "header": "tr|A0A8V0YC93-1|A0A3Q2TZK0_CHICK Computationally mapped isoform of Alpha-2,8-sialyltransferase 8E OS=Gallus gallus OX=9031 GN=ST8SIA5 PE=3 SV=1 CANONICAL=A0A3Q2TZK0-1" }, "locus": { "chromosome": "Z", "start_pos": 2207869, "end_pos": 2180502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023530.1", "url": "https://www.ensembl.org/id/ENSGALT00010023530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013560.1", "url": "https://www.ensembl.org/id/ENSGALP00010013560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:414797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414797", "resource": "KEGG Pathway" }, { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-GGA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LSD7-1", "protein_name": "Alpha-2,8-sialyltransferase 8E", "gene_name": "ST8SIA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRYADPSANRDLLGNRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRCLELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPSFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQLYENASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILATAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTCSCC", "length": 376 }, "evidence": [ { "id": "A0A3Q2TZK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TZK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8W4FIM2-1", "protein_name": "Alpha-2,8-sialyltransferase 8E", "gene_name": "ST8SIA5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRYADPSASRDLLGNRTLLFIFICAFALVTLLQQILYGRNYIKRGLQFGWQSGDPLANWTGLLNVTEDPAVQSGNDSSSRYFEFYEGPFEYNSTRCLELRHEILEVKVLSMSTLSRCCNAPSFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILATAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTCSCC", "length": 383 }, "evidence": [ { "id": "A0A3Q2TZK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TZK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15466-1", "protein_name": "Alpha-2,8-sialyltransferase 8E", "gene_name": "ST8SIA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRYADPSANRDLLGSRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRCLELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTCSCC", "length": 376 }, "evidence": [ { "id": "A0A3Q2TZK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TZK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70126-1", "protein_name": "Alpha-2,8-sialyltransferase 8E", "gene_name": "St8sia5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRYADPSANRDLLGNRTLLFIFICAFALVTLLQQILYSKSYIKRGFQFGWQRGDQQANWTGLFNDSDSPTEQNITGSSSRYFEFYKEPLEFNSTRCLELRQEILEVKVLSMVKQSELFERWKSLQICKWAMDTAEASLFKSTLSRCCNAPSFLFTTQKNTPVETNLRYEVESSGLYHIDQEIFKMFPKEMPYYRSQFKKCAVVGNGGILKNSGCGKEINSADFVFRCNLPPISGIYTTDVGEKTDVVTVNPSIIIDRFHKLEKWRRPFFSVLQRYENASVLLPAFYNVRNTLVSFRVKYMLDDFQSRQPVYFFHPQYLSSVSRYWLSLGVRARRISTGLILVTAALELCEEVHLFGFWAFPMNPSGFFITHHYYDNVKPKPGFHAMPSEIFTFLRMHSRGILRVHTGTCNCC", "length": 412 }, "evidence": [ { "id": "A0A3Q2TZK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TZK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZXC8-1", "protein_name": "Alpha-2,8-sialyltransferase 8E", "gene_name": "St8sia5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRYADPSANRDLLGNRTLLFIFICAFALVTLLQQILYSKSYIKRYFEFYKEPLEFNSTRCLELRQEILEVKVLSMVKQSELFERWKSLQICKWAMDASEASLFKSTLSRCCNAPNFLFTTQKNTPVETNLRYEVESSGLYHIDQEIFKMFPKEMPYYRSQFKKCAVVGNGGILKNSGCGKEINSADFVFRCNLPPISGIYTTDVGEKTDVVTVNPSIIIDRFHKLEKWRRPFFSVLQRYENASVLLPAFYNVRNTLVSFRVKYMLDDFQSRQPVYFFHPQYLSSVSRYWLSLGVRARRISTGLILVTAALELCEEVHLFGFWAFPMNPSGFFITHHYYDNVKPKPGFHAMPSEIFTFLRMHSRGILRVHTGTCNCC", "length": 376 }, "evidence": [ { "id": "A0A3Q2TZK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TZK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity", "id": "GO:0003828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003828", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" }, { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47592", "name": "", "equation": "a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GP1c (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47592", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47592" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TVN9-1", "uniprot_ac": "A0A3Q2TVN9", "uniprot_id": "A0A3Q2TVN9_CHICK", "mass": { "chemical_mass": 42328.0, "monoisotopic_mass": 42328.0 }, "refseq": { "ac": "XP_003641094", "name": "F-box only protein 25 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641094" }, "gene_names": [ { "name": "FBXO25", "type": "recommended", "evidence": [ { "id": "A0A3Q2TVN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ] }, { "name": "FBXO25", "type": "synonym", "evidence": [ { "id": "XP_003641094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641094" } ] } ], "protein_names": [ { "name": "F-box only protein 25", "type": "recommended", "evidence": [ { "id": "A0A3Q2TVN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 25 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003641094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641094" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003641094.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641094" } ] }, { "annotation": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RPL7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPL7#function" }, { "database": "UniProtKB", "id": "ARBA00037710", "url": "https://www.uniprot.org/uniprotkb/ARBA00037710#function" }, { "database": "UniProtKB", "id": "A0A8V0XEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEB8#function" }, { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9", "locus": { "chromosome": "3", "start_pos": 91336496, "end_pos": 91365115, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003727", "url": "https://www.ensembl.org/id/ENSGALG00010003727" } ] } } ], "crossref": [ { "id": "A0A3Q2TVN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TVN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016359", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016359", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22099", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22099", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421906", "url": "https://www.ncbi.nlm.nih.gov/gene/421906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421906", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWDTMAK", "url": "https://omabrowser.org/oma/group/AWDTMAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RPL7", "url": "https://www.orthodb.org/?gene=A0A1L1RPL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TVN9", "url": "https://www.orthodb.org/?gene=A0A3Q2TVN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEB8", "url": "https://www.orthodb.org/?gene=A0A8V0XEB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13123:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13123:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RPL7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFLGQDWRSPGWRWVKTEDGWKRFEPFGPALQGGNSQLNDISHTVILTGGDDDDEMYASEDCELAAKKRKKDHCRNNTDSQCFYRENWIYVHKESTRERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGAAQKNYFNILDKIVRKVMEDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWMCRLETIRLWQQQLKNLQMNKQVNNGLTLSDLPLHMLSNILHRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIDWKLMYFALQKYYPKKEQYGDTLHFCRHCSILFWKDSGHPCTASDPNTCLMPVSPQHFIDLFKF", "length": 361, "header": "tr|A0A3Q2TVN9-1|A0A3Q2TVN9_CHICK Isoform 1 of F-box only protein 25 OS=Gallus gallus OX=9031 GN=FBXO25 PE=4 SV=1 CANONICAL=A0A3Q2TVN9-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RPL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPL7/entry", "sequence": { "sequence": "MPFLGQDWRSPGWRWVKTEDGWKRFEPFGPALQGGNSQLNDISHTVILTGGDDDDEMYASEDCELAAKKRKKDHCRNNTDSQCFYRENWIYVHKESTRERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGAAQKNYFNILDKIVRKVMEDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWMCRLETIRLWQQQLKNLQMNKQVNNGLTLSDLPLHMLSNILHRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIDWKLMYFALQKYYPKKEQYGDTLHFCRHCSILFWKDYHLALLLKDSGHPCTASDPNTCLMPVSPQHFIDLFKF", "length": 370, "header": "tr|A0A1L1RPL7-1|A0A3Q2TVN9_CHICK Computationally mapped isoform of F-box only protein 25 OS=Gallus gallus OX=9031 GN=FBXO25 PE=4 SV=2 CANONICAL=A0A3Q2TVN9-1" }, "locus": { "chromosome": "3", "start_pos": 91360601, "end_pos": 91337545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008608.1", "url": "https://www.ensembl.org/id/ENSGALT00010008608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005038.1", "url": "https://www.ensembl.org/id/ENSGALP00010005038.1" } ] } }, { "isoform_ac": "A0A3Q2TVN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9/entry", "sequence": { "sequence": "MPFLGQDWRSPGWRWVKTEDGWKRFEPFGPALQGGNSQLNDISHTVILTGGDDDDEMYASEDCELAAKKRKKDHCRNNTDSQCFYRENWIYVHKESTRERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGAAQKNYFNILDKIVRKVMEDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWMCRLETIRLWQQQLKNLQMNKQVNNGLTLSDLPLHMLSNILHRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIDWKLMYFALQKYYPKKEQYGDTLHFCRHCSILFWKDSGHPCTASDPNTCLMPVSPQHFIDLFKF", "length": 361, "header": "tr|A0A3Q2TVN9-1|A0A3Q2TVN9_CHICK Isoform 1 of F-box only protein 25 OS=Gallus gallus OX=9031 GN=FBXO25 PE=4 SV=1 CANONICAL=A0A3Q2TVN9-1" }, "locus": { "chromosome": "3", "start_pos": 91360601, "end_pos": 91337545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008606.1", "url": "https://www.ensembl.org/id/ENSGALT00010008606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005037.1", "url": "https://www.ensembl.org/id/ENSGALP00010005037.1" } ] } }, { "isoform_ac": "A0A8V0XEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEB8/entry", "sequence": { "sequence": "MPFLGQDWRSPGWSILTGGDDDDEMYASEDCELAAKKRKKDHCRNNTDSQCFYRENWIYVHKESTRERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGAAQKNYFNILDKIVRKVMEDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWMCRLETIRLWQQQLKNLQMNKQVNNGLTLSDLPLHMLSNILHRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIDWKLMYFALQKYYPKKEQYGDTLHFCRHCSILFWKDSGHPCTASDPNTCLMPVSPQHFIDLFKF", "length": 329, "header": "tr|A0A8V0XEB8-1|A0A3Q2TVN9_CHICK Computationally mapped isoform of F-box only protein 25 OS=Gallus gallus OX=9031 GN=FBXO25 PE=4 SV=1 CANONICAL=A0A3Q2TVN9-1" }, "locus": { "chromosome": "3", "start_pos": 91360601, "end_pos": 91337545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008603.1", "url": "https://www.ensembl.org/id/ENSGALT00010008603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005035.1", "url": "https://www.ensembl.org/id/ENSGALP00010005035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421906", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BFY3-1", "protein_name": "F-box only protein 25", "gene_name": "FBXO25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRCESWSQELERQSNPCNVSHSIIINSEDEEIYNNEEHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVRLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHQNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILNWQQQLQNLQMTKQVDGGLTLSDLPVHMLSNILYRLSDGWDIVTLGQVTPTLSMLSEDRHLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPTKEQYGDTLHFCRHCSILFWKDSGHPCTAADPGSCFTPVSPQHFIDLFKF", "length": 358 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9PT00-1", "protein_name": "F-box only protein 25", "gene_name": "fbxo25", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRFDYFSHKLGDNINELGLEELDNDNKENVYVGDVCEVAAKKRKKDFFNNNTKSQFLFQERWIYVQKESTRERHGYCTLGEAFNRLDFSSAIQDVRRFNYVVKLLQLIAKSQLTSLSGAAQKNYFNVLEKIVRKVLEDHQNPRLIKALLHDLSSTLCILIREVGKSVLVGNINIWVCRLETILKWQQQLNNLQIPKQVSNGMTLSDLPLHMQTNILYQFTDAYDIINLGQATPTLQMLSEDRHLWKKLCQFHFAEKQFCRHLILSEKGHVDWKLMFFTLQKYYPQKEQYGDTLQFCRHCSILFWNDRHLALIFKDSGHPCTANDPDSCLTPVSPQHFIDLFKF", "length": 365 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GZN4-1", "protein_name": "F-box only protein 25", "gene_name": "Fbxo25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRCDSCSQELQSENGQYTINHSIILNNGEEEIFNNECEYAAKKRKKEHFGTDTAAHSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFTYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHQNPRLIKDLLQDLSSTLCILVRGVGKSVLVGNINIWICRLETVLSWQQQLQNLQMTKQVNSGLTLSDLPLHMLNNILYRFSDGWDIVTLGQVTPTLYMLSEDRRLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFTLQKYYPTKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF", "length": 357 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q641X7-1", "protein_name": "F-box only protein 25", "gene_name": "Fbxo25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRCDPCSHEIRSEDNQYPVNHSIILNSGEEEIFNNDCEYAAKKRKKQHFGNDTAAHSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFTYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHQNPRLIKDLLQDLSSTLCILVRGVGKSVLVGNINIWICRLETVLNWQEKLQNLQMTKQVNTGLTLSDLPLHMLNNILYRFSDGWDIVTLGQVTPTLYMLSEDRRLWKRLCQYHFAEKQFCRHLILSEKGHIEWKLMYFTLQKYYPTKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPEHFIDLFKF", "length": 357 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TCJ0-1", "protein_name": "F-box only protein 25", "gene_name": "FBXO25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNRCNISHSIILNSEDGEIFNNEEHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSPQHFIDLFKF", "length": 367 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2Y6-1", "protein_name": "F-box only protein 25", "gene_name": "Fbxo25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFLGQDWRSPGWSWIKTEDGWKRCDPCSHELRSEDSQYTINHSIILNSGEEEIFNNECEYAAKKRKKEHFGNDTAAHSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFTYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHQNPRLIKGLLQDLSSTLGILVRGVGKSVLVGNINIWICRLETVLSWQQQLQNLQVTKQVNTGLTLSDLPLHMLNNILYRFSDGWDIVTLGQVTPTLYMLSEDRRLWKRLCQYHFAEQQFCRHLILSEKGHIEWKLMYFTLQKYYPTKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPEHFIDLFKF", "length": 357 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTM4-1", "protein_name": "F-box only protein 32", "gene_name": "Dmel\\CG11658", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAFISKDFRSPGETWIKTDGGWERSKVLECGGKRKRHHSEGSSSYQDSDSSEEEAVMPPHYHITIRCTREIAGFNGLSEAVKRLDFRRSVRDRKRFHYICAFLLLVSNKGIASLPGSAQRQLLQMVEEVASHVNDSQQHPNVLRGLALKLEHIVSQENQKCWGKPLGSTYLWKEHMATIKRIQRVASQIEIREPDPEAKPKLHELPEECVREIILCIADHRDLESAAEAWETMAKLVSEQRIWRELTRFHFNQRQIHTILDLDKFKQMGEIKDWKQIYHQLRRTYGVNDDYQFAEVLALCRSCCCLFWPSDGHPCIVDQSPDYKQRLEEAGGQLALAQPVPPAQFLKYFSL", "length": 351 }, "evidence": [ { "id": "A0A3Q2TVN9", "url": "https://omabrowser.org/oma/group/A0A3Q2TVN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZHL0-1", "uniprot_ac": "Q5ZHL0", "uniprot_id": "VA0D2_CHICK", "mass": { "chemical_mass": 40400.0, "monoisotopic_mass": 40400.0 }, "refseq": { "ac": "NP_001008455", "name": "V-type proton ATPase subunit d 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" }, "gene_names": [ { "name": "ATP6V0D2", "type": "recommended", "evidence": [ { "id": "Q5ZHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ] }, { "name": "ATP6V0D2", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] }, { "name": "RCJMB04_37b12", "type": "synonym", "evidence": [ { "id": "Q5ZHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit d 2", "type": "recommended", "evidence": [ { "id": "Q5ZHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0/entry#names_and_taxonomy" } ] }, { "name": "ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] }, { "name": "ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] }, { "name": "V-ATPase subunit d 2", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" }, { "id": "Q5ZHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase subunit d 2", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] }, { "name": "Vacuolar proton pump subunit d 2", "type": "synonym", "evidence": [ { "id": "Q5ZHL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0/entry#names_and_taxonomy" } ] }, { "name": "vacuolar proton pump subunit d 2", "type": "synonym", "evidence": [ { "id": "NP_001008455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721124.1, SRR12888501.430536.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992428, SAMEA103992437 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000044.1. On Dec 16, 2004 this sequence version replaced XP_418321.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455" } ] }, { "annotation": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UC00", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC00#function" }, { "database": "UniProtKB", "id": "PIRNR018497", "url": "https://www.uniprot.org/uniprotkb/PIRNR018497#function" }, { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0#function" }, { "database": "UniProtKB", "id": "Q80SY3", "url": "https://www.uniprot.org/uniprotkb/Q80SY3#function" }, { "database": "UniProtKB", "id": "P61421", "url": "https://www.uniprot.org/uniprotkb/P61421#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP6V0D2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0", "locus": { "chromosome": "2", "start_pos": 122639524, "end_pos": 122621620, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013339", "url": "https://www.ensembl.org/id/ENSGALG00010013339" } ] } } ], "crossref": [ { "id": "Q5ZHL0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZHL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034294", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034294", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420210", "url": "https://www.ncbi.nlm.nih.gov/gene/420210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420210", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETLFPTC", "url": "https://omabrowser.org/oma/group/ETLFPTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UC00", "url": "https://www.orthodb.org/?gene=A0A3Q2UC00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZHL0", "url": "https://www.orthodb.org/?gene=Q5ZHL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZHL0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZHL0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001008455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UC00", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UC00-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHL0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGYSEFYFNVDHGYLEGLVRGFKAGILTSADYVNLAQCETLEDLKLHLQTTDYGNFLANESGPLTISTIDDKLKTKLLTEFHYFRNHAFEPLTTFLNFITYSYMIDNIILLITGTLHQRPIAELVPKCHPLGSFEQMEAVSIASNPTELFNAILVDTPLAAFFQDCLSENDLDEMNVEIMRNKLYKSYLEAFYKFCEKQGGTTAEIMKPILEFEADRRAFIITINSFGTELSKEDREKLYPTCGKLYPEGLHLLANADDYEQVKCVADYYAEYKAVFEGVGNDSGEKTLEDAFFEHEIKLNVLAFNNQFHFGVFYAYIKLKEQECRNIVWIAECISQRHRTKINNYIPIF", "length": 351, "header": "sp|Q5ZHL0-1|VA0D2_CHICK Isoform 1 of V-type proton ATPase subunit d 2 OS=Gallus gallus OX=9031 GN=ATP6V0D2 PE=2 SV=1 CANONICAL=Q5ZHL0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UC00-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC00/entry", "sequence": { "sequence": "MPGYSEFYFNVDHGYLEGLVRGFKAGILTSADYVNLAQCETLEDLKLHLQTTDYGNFLANESGPLTISTIDDKLKTKLLTEFHYFRNHAFEPLTTFLNFITYSYMIDNIILLITGTLHQRPIAELVPKCHPLGSFEQMEAVSIASNPTELFNAILVDTPLAAFFQDCLSENDLDEMNVEIMRNKLYKSYLEAFYKFCEKQGGTTAEIMKPILEFEADRRAFIITINSFGTELSKEDREKLYPTCGKLYPEGLHLLANADDYEQVKCVADYYAIKLNVLAFNNQFHFGVFYAYIKLKEQECRNIVWIAECISQRHRTKINNYIPIF", "length": 325, "header": "tr|A0A3Q2UC00-1|VA0D2_CHICK Computationally mapped isoform of V-type proton ATPase subunit d 2 OS=Gallus gallus OX=9031 GN=ATP6V0D2 PE=2 SV=1 CANONICAL=Q5ZHL0-1" }, "locus": { "chromosome": "2", "start_pos": 122638969, "end_pos": 122621775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032100.1", "url": "https://www.ensembl.org/id/ENSGALT00010032100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018890.1", "url": "https://www.ensembl.org/id/ENSGALP00010018890.1" } ] } }, { "isoform_ac": "Q5ZHL0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0/entry#Q5ZHL0-1", "sequence": { "sequence": "MPGYSEFYFNVDHGYLEGLVRGFKAGILTSADYVNLAQCETLEDLKLHLQTTDYGNFLANESGPLTISTIDDKLKTKLLTEFHYFRNHAFEPLTTFLNFITYSYMIDNIILLITGTLHQRPIAELVPKCHPLGSFEQMEAVSIASNPTELFNAILVDTPLAAFFQDCLSENDLDEMNVEIMRNKLYKSYLEAFYKFCEKQGGTTAEIMKPILEFEADRRAFIITINSFGTELSKEDREKLYPTCGKLYPEGLHLLANADDYEQVKCVADYYAEYKAVFEGVGNDSGEKTLEDAFFEHEIKLNVLAFNNQFHFGVFYAYIKLKEQECRNIVWIAECISQRHRTKINNYIPIF", "length": 351, "header": "sp|Q5ZHL0-1|VA0D2_CHICK Isoform 1 of V-type proton ATPase subunit d 2 OS=Gallus gallus OX=9031 GN=ATP6V0D2 PE=2 SV=1 CANONICAL=Q5ZHL0-1" }, "locus": { "chromosome": "2", "start_pos": 122638969, "end_pos": 122621775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032108.1", "url": "https://www.ensembl.org/id/ENSGALT00010032108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018898.1", "url": "https://www.ensembl.org/id/ENSGALP00010018898.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:420210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420210", "resource": "KEGG Pathway" }, { "id": "R-GGA-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-GGA-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-GGA-917977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917977", "resource": "Reactome", "description": "Transferrin endocytosis and recycling" }, { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RXD2-1", "protein_name": "V-type proton ATPase subunit", "gene_name": "ATP6V0D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFEGAELYFNVDHGYLEGLVRGCKAGLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANQPNPLTVSIIDTEMRKKLCREFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEILVKCHPLGRFTEMEAVNIAETPSDLFNAILVETPLAPFFQDCMSENTLDELNIEILRNKLYKSYIETFYKFCKNHGDVTAEIMCPILEFEADRRAFIITLNSFGTELSKEDRKTLYPTCGKLYPEGLRLLAQAEDFEQMKRVADHYGVYKPLFEAVGDGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYTKLKEQEIRNVVWIAECISQRHRTKINSYIPIL", "length": 351 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2KJB6-1", "protein_name": "V-type proton ATPase subunit d 2", "gene_name": "ATP6V0D2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLESAELNFNADHGYLEGLVRGCKAGLLTRRDYVNLVQCENLEDLKIHLQTTDYGNFLANQATPLTVSVIDTEMRKKLCREFEYFRNHSLEPLSTFFTYMTCSYMIDNVILLMNGALQNKPVKDVLVKCHPLGHFTEMEAVNIAETPSDLFNAILVETPLAPFFQDCTSENALDELNIEILRNKLYKSYIEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTCGKLHPEGLRLLAQAEDFEQMKRVADSYGVYKPLFEAVSDSSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYTKLKEQEMRNIVWIAECISQRQRTKINSYIPIL", "length": 351 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FVL0-1", "protein_name": "V-type proton ATPase subunit d 2", "gene_name": "Atp6v0d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETAELYFNVDHGYLEGLVRGCKASLLTQQDYVNLVQCETLEDLKIHLQTTDYGNFLAHETNPLTVSKIDTEMRKKLCREFDYFRNHSLEPLSTFFTYMTCSYMIDNIILLMNGALQKKSVKEVLAKCHPLGRFTEMEAVNIAESASELFKAVLVETPLAPFFQDCMSENTLDELNIELLRNKLYKSYLEAFYKFCKDHGDVTAEVMCPILEFEADRRALIITLNSFGTELSKEDRETLFPTCGKLYPEGLRLLAQAEDFEHMKRVADNYGVYKPLFDAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEMRNIVWIAECISQRHRTKINSYIPIL", "length": 350 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80SY3-1", "protein_name": "V-type proton ATPase subunit d 2", "gene_name": "Atp6v0d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLETAELYFNVDHGYLEGLVRGCKASLLTQQDYVNLVQCETLEDLKIHLQTTDYGNFLANETNPLTVSKIDTEMRKKLCREFDYFRNHSLEPLSTFLTYMTCSYMIDNIILLMNGALQKKSVKEVLAKCHPLGRFTEMEAVNIAETPSDLFKAVLVETPLAPFFQDCMSENTLDELNIELLRNKLYKSYLEAFYKFCKDHGDVTADVMCPILEFEADRRALIITLNSFGTELSKEDRETLFPTCGRLYPEGLRLLAQAEDFEQMKRVADNYGVYKPLFDAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEMRNIVWIAECISQRHRTKINSYIPIL", "length": 350 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8Y2-1", "protein_name": "V-type proton ATPase subunit d 2", "gene_name": "ATP6V0D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANHTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIELLRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL", "length": 350 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LJI5-1", "protein_name": "V-type proton ATPase subunit d1", "gene_name": "VHA-d1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYGFEALTFNIHGGYLEAIVRGHRAGLLTTADYNNLCQCENLDDIKMHLSATKYGSYLQNEPSPLHTTTIVEKCTLKLVDDYKHMLCQATEPMSTFLEYIRYGHMIDNVVLIVTGTLHERDVQELIEKCHPLGMFDSIATLAVAQNMRELYRLVLVDTPLAPYFSECLTSEDLDDMNIEIMRNTLYKAYLEDFYKFCQKLGGATAEIMSDLLAFEADRRAVNITINSIGTELTREDRKKLYSNFGLLYPYGHEELAICEDIDQVRGVMEKYPPYQAIFSKMSYGESQMLDKAFYEEEVRRLCLAFEQQFHYAVFFAYMRLREQEIRNLMWISECVAQNQKSRIHDSVVYMF", "length": 351 }, "evidence": [ { "id": "Q5ZHL0", "url": "https://omabrowser.org/oma/group/Q5ZHL0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" }, { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase complex", "id": "GO:0016471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016471", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" }, { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" }, { "name": "plasma membrane proton-transporting V-type ATPase complex", "id": "GO:0033181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033181", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZHL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], 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"glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RWJ7-1", "uniprot_ac": "A0A1L1RWJ7", "uniprot_id": "A0A1L1RWJ7_CHICK", "mass": { "chemical_mass": 87251.0, "monoisotopic_mass": 87251.0 }, "refseq": { "ac": "XP_424941", "name": "phospholipase A-2-activating protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424941" }, "gene_names": [ { "name": "PLAA", "type": "recommended", "evidence": [ { "id": "A0A1L1RWJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ] }, { "name": "PLAA", "type": "synonym", "evidence": [ { "id": "XP_424941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424941" } ] } ], "protein_names": [ { "name": "Phospholipase A-2-activating protein", "type": "recommended", "evidence": [ { "id": "A0A1L1RWJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7/entry#names_and_taxonomy" } ] }, { "name": "phospholipase A-2-activating protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424941" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_424941.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424941" } ] }, { "annotation": "Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XVG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG5#function" }, { "database": "UniProtKB", "id": "ARBA00094504", "url": "https://www.uniprot.org/uniprotkb/ARBA00094504#function" }, { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7#function" }, { "database": "UniProtKB", "id": "A0A8V0XQN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQN2#function" }, { "database": "UniProtKB", "id": "A0A8V0XSP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP5#function" }, { "database": "UniProtKB", "id": "A0A8V0XY99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY99#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLAA", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7", "locus": { "chromosome": "Z", "start_pos": 69082752, "end_pos": 69100193, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006465", "url": "https://www.ensembl.org/id/ENSGALG00010006465" } ] } } ], "crossref": [ { "id": "A0A1L1RWJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RWJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001782", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427365", "url": "https://www.ncbi.nlm.nih.gov/gene/427365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DKCIYYW", "url": "https://omabrowser.org/oma/group/DKCIYYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWJ7", "url": "https://www.orthodb.org/?gene=A0A1L1RWJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLD5", "url": "https://www.orthodb.org/?gene=A0A8V0XLD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQN2", "url": "https://www.orthodb.org/?gene=A0A8V0XQN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSP5", "url": "https://www.orthodb.org/?gene=A0A8V0XSP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVG5", "url": "https://www.orthodb.org/?gene=A0A8V0XVG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY99", "url": "https://www.orthodb.org/?gene=A0A8V0XY99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19849:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19849:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 794, "header": "tr|A0A1L1RWJ7-1|A0A1L1RWJ7_CHICK Isoform 1 of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=2 CANONICAL=A0A1L1RWJ7-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7/entry", "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 794, "header": "tr|A0A1L1RWJ7-1|A0A1L1RWJ7_CHICK Isoform 1 of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=2 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69099978, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015394.1", "url": "https://www.ensembl.org/id/ENSGALT00010015394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009000.1", "url": "https://www.ensembl.org/id/ENSGALP00010009000.1" } ] } }, { "isoform_ac": "A0A8V0XLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLD5/entry", "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYADFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 738, "header": "tr|A0A8V0XLD5-1|A0A1L1RWJ7_CHICK Computationally mapped isoform of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=1 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69099978, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015390.1", "url": "https://www.ensembl.org/id/ENSGALT00010015390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008999.1", "url": "https://www.ensembl.org/id/ENSGALP00010008999.1" } ] } }, { "isoform_ac": "A0A8V0XQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQN2/entry", "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 738, "header": "tr|A0A8V0XQN2-1|A0A1L1RWJ7_CHICK Computationally mapped isoform of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=1 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69099978, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015387.1", "url": "https://www.ensembl.org/id/ENSGALT00010015387.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008998.1", "url": "https://www.ensembl.org/id/ENSGALP00010008998.1" } ] } }, { "isoform_ac": "A0A8V0XSP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP5/entry", "sequence": { "sequence": "MFLKDLCLSSPGRQHCVAVLNAVSCSVLSSGKMESSGGSPVESHWDDLRPRGKLFPIWGKAKRPGTAWPGDYDGSHPCFLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 823, "header": "tr|A0A8V0XSP5-1|A0A1L1RWJ7_CHICK Computationally mapped isoform of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=1 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69099542, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015381.1", "url": "https://www.ensembl.org/id/ENSGALT00010015381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008996.1", "url": "https://www.ensembl.org/id/ENSGALP00010008996.1" } ] } }, { "isoform_ac": "A0A8V0XVG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG5/entry", "sequence": { "sequence": "MAGDGGVYRLRCSLLGHEQDVRGITRGLFPEGGFVSVSRDRTARLWTPDGSGKMESSGGSPVESHWDDLRPRGKLFPIWGKAKRPGTAWPGDYDGSHPCFLNRGFTEMHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGAGRYVPGSASNVVAPVGGHDPYTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 844, "header": "tr|A0A8V0XVG5-1|A0A1L1RWJ7_CHICK Computationally mapped isoform of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=1 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69099978, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015384.1", "url": "https://www.ensembl.org/id/ENSGALT00010015384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008997.1", "url": "https://www.ensembl.org/id/ENSGALP00010008997.1" } ] } }, { "isoform_ac": "A0A8V0XY99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY99/entry", "sequence": { "sequence": "MHCMRGHSNFVSCVCIIPPSDLYPRGLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCSLSSGKFGTLLSGSWDTTCKVWLNDRCMMTLQGHTAAIWAVKILPEQGLMLTGSADKTIKLWKAGRCERTYAGHEDCVRGLAILSEMEFLSCSNDASVRRWHISGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIWKQGECVQTIRLPAQSVWCCCVLDNDDIVVGASDGIIRVFTKSLERTASAEEIQAFENELSQASIDPKTGDLGDINADDLPGKEHLKDPGMRDGQTRLIKDNGKVEAYQWSVSEGRWIKIGDVVGSSGGTQQTSGKVLFEGKEYDYVFTIDVNESGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQAPLNTNTEFSDPFTGAGRYVPGSSSLSNTAPAADPFTGMGAYQSAKAENIYFPKKDAVTFDQANPTQILGKLKELNGNAAEEQKLTEDDLIILEKLLSATCNTSAEMPTAQQIQTLWKAINWPEDIVFPALDILRLSVRHPIVNENFCGEKAHVQFIHLLLKFLNPQGKPANQLLALRALCNCFVSQAGQKLLMEQRDEIMTQAIEVKSGNNKNVHIALATLTLNYAVCLHKVNNIEGKAQCLSVISTVMEVVKDLEAVFRLLVALGTLISDDKNAVQLAKSLGVDSQIKKYVSVSEPAKVKECCRFVLNLL", "length": 713, "header": "tr|A0A8V0XY99-1|A0A1L1RWJ7_CHICK Computationally mapped isoform of Phospholipase A-2-activating protein OS=Gallus gallus OX=9031 GN=PLAA PE=1 SV=1 CANONICAL=A0A1L1RWJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 69098079, "end_pos": 69082914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015377.1", "url": "https://www.ensembl.org/id/ENSGALT00010015377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008995.1", "url": "https://www.ensembl.org/id/ENSGALP00010008995.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R9S8-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "PLAA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASGATRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWVPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDMYPHGLIATGGNDHNICIFSLESPAPLYVLKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRKWQITGECLEVFYGHTNYIYSISVFPNCKDFVTTGEDRSLRIWKHGECAQTIRLPAQSIWCCCVLNNGDIVVGASDGIIRVFTESEDRTANAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSERRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNISDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTQGQMLGLGNTNFSDPFTGGGRYVPGSSSGSSNTLPVADPFTGGGRYVPGSANMGTMMAGVDPFTGNSAYQSAASKTVNIYFPKKEAVTFDQANPTQILGKLKELNGTASEDKKLTEEDLVLLEKILSLICNNSSEKPTAQQLQTLWKAVNWPEDIVFPALDILRLSIKHPSVNENFCNEKEGTQFSSHLINLLNPKGKPANQLLALRTFCNCFVGKAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTVLEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKFASVSEPAKVSECCRLILNLL", "length": 796 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4J9W8-1", "protein_name": "Transducin family protein / WD-40 repeat family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVMDIDFNEYKLRCELHGHDDDVRGICVCNDENIATSSRDRTIRVWSLDPSDKRKYTSEKILLGHTSFVGPLAWIPPTDEYPEGRLVSGSMDTFVFVWNLMNGENIQTLKGHQMQVTGVAIDNEDIVSSSVDQTLKRWRNGQLVESWDAHQSPIQAVIRLPSGELVSGSSDASLKLWKGKTSLQTLSGHTDTVRGLAVMPDLGFLSASHDGSIRLWALSGEVLLEMVGHTSLVYSVDAHSSGLIVSASEDRHAKIWKDGVCVQSLEHPGCIWDAKFLETGDIVTACSDGVVRVWTVRHDAIADQMEIDAYDSQISQYKLSRKKVGGLKLDELPGLDSLTSPGTSDGQTKVVREGDNGVAYAWNMKEQRWDKIGEVVDGPDGVADRPIHEGVQYDFVFDVDIGDGEPIRKLPYNRSDNPYDAADKWLLKENLPFAYRQQIVEFILQNSGQKDFNFNPSFRDPFTGANAYVPGQASRTAATPAKPLYKHIPKRGVLVFDAAQYDGILKKMTEFNTTLRSDAVNNDKSLTELEVSRVGAIVNILKDTSHYHSTNFADMDIALLLKVLQAWPPAMMFPATDIVRMLVLHHHGASLLIKHVENNNDLLLDLIKKVTEDSALPANLLTTVRVLVNLFKNSSFHYWLQTHHSQILDAFSNCYSSPNKNLQLAYSTLLLNYAVLLIEKKDQEGQAQVLSAALQVPEEEAADVDSKFRSLVAIGSLMLEGLVKKIAIDFDVESIAKSAKASKEAKIAEVGADIDLVIRQ", "length": 760 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3HH63-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSEIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESQDRTASVEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSEDPWLAAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQAADPFTGAGRYMPGSAGMGTSMAGVDPFTGSSAYRSAASKTVNIYFPKKEALTFDQANPIQILGKLKELNGTAPEDKKLTEDDLVLLEKILSLICNNSSEKPTAQQLQILWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLIHLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSQAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEPAKVSECCRLILNLL", "length": 795 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27612-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGASRYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLSEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMTGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGTAPEEKKLTEDDLVLLEKILSLICNNSSEKPTAQQLQILWKAINWPEDIVFPALDILRLSIKHPNVNENFCNEKGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYVSVSEPAKVSECCRLVLHLL", "length": 794 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54319-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "Plaa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPGAFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTEADERTASAEEIKAFERELSQATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGERVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTSFSDPFTGGGRYVPGTSGPSNTVQTADPFTGAGRYMPGSAGMDTTMAGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGSAPEEKKLTEDDLVLLEKILSLICGNASEKPTAQQLQVLWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHNIEGKAQCLSVISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEPAKVSECCRLILNLL", "length": 795 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VPY2-1", "protein_name": "Phospholipase A2 activator protein, isoform B", "gene_name": "Plap", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPSLDNYKLSCELLGHSMDVRAVAVGPPTPEGRQTILSGSRDKSTKVWKPHGNEYLESLTLQDHKNFISYICFLESERWICTASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFVALEGHEAAVWAVATLKEQRKYVTGGADRNIYYWNAKGEKLRLLKGHTDCVRGVMGLDANTLLSCGNDAVLRFWNEDGECVREMNGHSNYIYSMARNEALGDQVVVSCGEDSTLRMWNVITGDELGAPIIHPGISVWSVTCLQNGDIVTGCSDGVVRVFSHVPARQASEAVLKAFDLVVATRKSQINEEIGGVKKTDLPGPEALLSNGTREGQTKMVRHADGSVKCYTWTLGNWNLVGDVTGATGGTQSNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDDPWQAAQTFIHRHSLPQAYLDQVANFIIKNSEGPVLMEQAPTGYQDPFTGGSRYVPGSSNTNMGSGGNVDPFTGASSYSTASSNAQSQVDVNFVRSGDKHFPVSNYRIFDTCDAKKVLEKMIEFNGKLSLPDGRVGEEVLLAVIKLADQSPELDLTSLEALAILLKWPASMQFPVLDILRLAVRNEAIFSVLNNSHNFLATVIPQLSGSAPNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGSANLQIAVATFYLNLTISQTLDVAKSEVCHVVTSGIVELLKWAKDLEACYRSMQAIGNLTTTSCGQETIAQVVSVDYVMDKLRELTITPQDKNFSKVNSVGQALLAVF", "length": 787 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y263-1", "protein_name": "Phospholipase A-2-activating protein", "gene_name": "PLAA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGEKVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPGSSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEAVTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILWKAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLALRTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIEGKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSEPAKVSECCRFILNLL", "length": 795 }, "evidence": [ { "id": "A0A1L1RWJ7", "url": "https://omabrowser.org/oma/group/A0A1L1RWJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "cytoplasmic ubiquitin ligase complex", "id": "GO:0000153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000153", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "ubiquitin recycling", "id": "GO:0010992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010992", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWJ7" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWJ7", "url": 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"MAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 388, "header": "tr|A0A3Q2UCB0-1|A0A3Q2UCB0_CHICK Isoform 1 of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UCB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCB0/entry", "sequence": { "sequence": "MAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 388, "header": "tr|A0A3Q2UCB0-1|A0A3Q2UCB0_CHICK Isoform 1 of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68168885, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013696.1", "url": "https://www.ensembl.org/id/ENSGALT00010013696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008101.1", "url": "https://www.ensembl.org/id/ENSGALP00010008101.1" } ] } }, { "isoform_ac": "A0A8V0XIW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIW0/entry", "sequence": { "sequence": "MRAALSARRQLQTNMAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 402, "header": "tr|A0A8V0XIW0-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68202604, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013690.1", "url": "https://www.ensembl.org/id/ENSGALT00010013690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008098.1", "url": "https://www.ensembl.org/id/ENSGALP00010008098.1" } ] } }, { "isoform_ac": "A0A8V0XIW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIW4/entry", "sequence": { "sequence": "METQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 354, "header": "tr|A0A8V0XIW4-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68166468, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013700.1", "url": "https://www.ensembl.org/id/ENSGALT00010013700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008103.1", "url": "https://www.ensembl.org/id/ENSGALP00010008103.1" } ] } }, { "isoform_ac": "A0A8V0XN16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN16/entry", "sequence": { "sequence": "MGPVGQEQMHSAAVLKFPATLGSWEQSVCVWKYLLFAVRRQLQTNMAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 433, "header": "tr|A0A8V0XN16-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68198016, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013680.1", "url": "https://www.ensembl.org/id/ENSGALT00010013680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008092.1", "url": "https://www.ensembl.org/id/ENSGALP00010008092.1" } ] } }, { "isoform_ac": "A0A8V0XT02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT02/entry", "sequence": { "sequence": "MHPLTKEQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 358, "header": "tr|A0A8V0XT02-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68182057, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013678.1", "url": "https://www.ensembl.org/id/ENSGALT00010013678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008091.1", "url": "https://www.ensembl.org/id/ENSGALP00010008091.1" } ] } }, { "isoform_ac": "A0A8V0XT20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT20/entry", "sequence": { "sequence": "MAVRLCDVASLLRSGSWAAEPWTGVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 387, "header": "tr|A0A8V0XT20-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68168885, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013709.1", "url": "https://www.ensembl.org/id/ENSGALT00010013709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008111.1", "url": "https://www.ensembl.org/id/ENSGALP00010008111.1" } ] } }, { "isoform_ac": "A0A8V0XVM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVM9/entry", "sequence": { "sequence": "MSACFIILFLPFSTPFQNYPRFPSLRLVLSGRSHCPSLLTRESCAVTFCSEPSGRRKLGAECVCVEVLTVCCKQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 437, "header": "tr|A0A8V0XVM9-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=1 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68204174, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013685.1", "url": "https://www.ensembl.org/id/ENSGALT00010013685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008094.1", "url": "https://www.ensembl.org/id/ENSGALP00010008094.1" } ] } }, { "isoform_ac": "R4GFW0-1", "url": "https://www.uniprot.org/uniprotkb/R4GFW0/entry", "sequence": { "sequence": "MSACFIILFLPFSTPFQNYPRFPSLRLVLSGRSHCPSLLTRESCAVTFCSEPSGRRRQLQTNMAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTAHGSNAINNCSSPIDSGNTEDSKTNLIVNYLPQSMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGMSRGVGFIRFDKRIEAEEAIKGLNGQKPPAATEPITVKFANNPSQKTNQAILSQLYHSPNRRYPAPLAQQAQRFRLDNLLNMAYGVKSRFPPMTIDGMTSLAGINIPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 450, "header": "tr|R4GFW0-1|A0A3Q2UCB0_CHICK Computationally mapped isoform of ELAV-like protein OS=Gallus gallus OX=9031 GN=ELAVL2 PE=1 SV=3 CANONICAL=A0A3Q2UCB0-1" }, "locus": { "chromosome": "Z", "start_pos": 68204174, "end_pos": 68122016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013704.1", "url": "https://www.ensembl.org/id/ENSGALT00010013704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008106.1", "url": "https://www.ensembl.org/id/ENSGALP00010008106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770158", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LW62-1", "protein_name": "ELAV-like protein", "gene_name": "ELAVL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRPLGEELAISGLRWVALEGCGERQALIQSSAGFPTFAFEAENSTPHRRQLQTNMAVRLCDVASLLRSGSWAAEPWTGQVIAAMETQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 443 }, "evidence": [ { "id": "A0A3Q2UCB0", "url": "https://omabrowser.org/oma/group/A0A3Q2UCB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4I3B3-1", "protein_name": "Polyadenylate-binding protein RBP47A", "gene_name": "RBP47A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQTPNNNGSTDSVLPPTSAGTTPPPPLQQSTPPPQQQQQQQWQQQQQWMAAMQQYPAAAMAMMQQQQMMMYPHPQYAPYNQAAYQQHPQFQYAAYQQQQQQHHQSQQQPRGGSGGDDVKTLWVGDLLHWMDETYLHTCFSHTNEVSSVKVIRNKQTCQSEGYGFVEFLSRSAAEEALQSFSGVTMPNAEQPFRLNWASFSTGEKRASENGPDLSIFVGDLAPDVSDAVLLETFAGRYPSVKGAKVVIDSNTGRSKGYGFVRFGDENERSRAMTEMNGAFCSSRQMRVGIATPKRAAAYGQQNGSQALTLAGGHGGNGSMSDGESNNSTIFVGGLDADVTEEDLMQPFSDFGEVVSVKIPVGKGCGFVQFANRQSAEEAIGNLNGTVIGKNTVRLSWGRSPNKQWRSDSGNQWNGGYSRGQGYNNGYANQDSNMYATAAAAVPGAS", "length": 445 }, "evidence": [ { "id": "A0A3Q2UCB0", "url": "https://omabrowser.org/oma/group/A0A3Q2UCB0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q12926-1", "protein_name": "ELAV-like protein 2", "gene_name": "ELAVL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 359 }, "evidence": [ { "id": "A0A3Q2UCB0", "url": "https://omabrowser.org/oma/group/A0A3Q2UCB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60899-1", "protein_name": "ELAV-like protein 2", "gene_name": "Elavl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 360 }, "evidence": [ { "id": "A0A3Q2UCB0", "url": "https://omabrowser.org/oma/group/A0A3Q2UCB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CH84-1", "protein_name": "ELAV-like protein 2", "gene_name": "Elavl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIDNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA", "length": 359 }, "evidence": [ { "id": "A0A3Q2UCB0", "url": "https://omabrowser.org/oma/group/A0A3Q2UCB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCB0" } ], "pmid": "" }, { "name": "protein-RNA adaptor activity", "id": "GO:0140517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140517", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UCB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 383, "end_pos": 385 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TT83-1", "uniprot_ac": "A0A3Q2TT83", "uniprot_id": "A0A3Q2TT83_CHICK", "mass": { "chemical_mass": 13546.0, "monoisotopic_mass": 13546.0 }, "refseq": { "ac": "NP_001376356", "name": "short coiled-coil protein isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" }, "gene_names": [ { "name": "SCOC", "type": "recommended", "evidence": [ { "id": "A0A3Q2TT83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83" } ] }, { "name": "BERT", "type": "synonym", "evidence": [ { "id": "NP_001376356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" } ] }, { "name": "SCOC", "type": "synonym", "evidence": [ { "id": "NP_001376356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" } ] } ], "protein_names": [ { "name": "Short coiled-coil protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2TT83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83/entry#names_and_taxonomy" } ] }, { "name": "short coiled-coil protein A", "type": "synonym", "evidence": [ { "id": "NP_001376356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" } ] }, { "name": "short coiled-coil protein isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001376356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2365562.52595.1, SRR13267659.6484.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Dec 21, 2020 this sequence version replaced XP_015131652.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356" } ] }, { "annotation": "Positive regulator of amino acid starvation-induced autophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XW13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW13#function" }, { "database": "UniProtKB", "id": "ARBA00002743", "url": "https://www.uniprot.org/uniprotkb/ARBA00002743#function" }, { "database": "UniProtKB", "id": "A0A3Q2TT83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TT83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCOC", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83", "locus": { "chromosome": "4", "start_pos": 29214526, "end_pos": 29205973, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009127", "url": "https://www.ensembl.org/id/ENSGALG00010009127" } ] } } ], "crossref": [ { "id": "A0A3Q2TT83", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TT83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009813", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009813", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422446", "url": "https://www.ncbi.nlm.nih.gov/gene/422446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TT83", "url": "https://www.orthodb.org/?gene=A0A3Q2TT83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XW13", "url": "https://www.orthodb.org/?gene=A0A8V0XW13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21614:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21614:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10224", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10224", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TT83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TT83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLPVDEEDGSFTNISLADDPDRRSGRLSSKAERARSTMMNADMDAVEAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK", "length": 120, "header": "tr|A0A3Q2TT83-1|A0A3Q2TT83_CHICK Isoform 1 of Short coiled-coil protein OS=Gallus gallus OX=9031 GN=SCOC PE=1 SV=1 CANONICAL=A0A3Q2TT83-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TT83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83/entry", "sequence": { "sequence": "MDLPVDEEDGSFTNISLADDPDRRSGRLSSKAERARSTMMNADMDAVEAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK", "length": 120, "header": "tr|A0A3Q2TT83-1|A0A3Q2TT83_CHICK Isoform 1 of Short coiled-coil protein OS=Gallus gallus OX=9031 GN=SCOC PE=1 SV=1 CANONICAL=A0A3Q2TT83-1" }, "locus": { "chromosome": "4", "start_pos": 29212349, "end_pos": 29206145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021772.1", "url": "https://www.ensembl.org/id/ENSGALT00010021772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012448.1", "url": "https://www.ensembl.org/id/ENSGALP00010012448.1" } ] } }, { "isoform_ac": "A0A8V0XW13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW13/entry", "sequence": { "sequence": "TQVIPNLPQNIRISGHPAGLTNPHGPARCWDLSHHFCAPQREGKLQGSGCGPPHARPAFRRANRPPAGSGVQPPGYSTCDRRSGRLSSKAERARSTMMNADMDAVEAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK", "length": 178, "header": "tr|A0A8V0XW13-1|A0A3Q2TT83_CHICK Computationally mapped isoform of Short coiled-coil protein OS=Gallus gallus OX=9031 GN=SCOC PE=1 SV=1 CANONICAL=A0A3Q2TT83-1" }, "locus": { "chromosome": "4", "start_pos": 29212349, "end_pos": 29210602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021768.1", "url": "https://www.ensembl.org/id/ENSGALT00010021768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012444.1", "url": "https://www.ensembl.org/id/ENSGALP00010012444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TT83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TT83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TT83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 120, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TT83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TT83" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RVT9-1", "uniprot_ac": "A0A1L1RVT9", "uniprot_id": "A0A1L1RVT9_CHICK", "mass": { "chemical_mass": 35307.0, "monoisotopic_mass": 35307.0 }, "refseq": { "ac": "XP_024997905", "name": "transmembrane protein 248", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997905" }, "gene_names": [ { "name": "TMEM248", "type": "recommended", "evidence": [ { "id": "A0A1L1RVT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9" } ] }, { "name": "TMEM248", "type": "synonym", "evidence": [ { "id": "XP_024997905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997905" } ] } ], "protein_names": [ { "name": "Transmembrane protein 248", "type": "recommended", "evidence": [ { "id": "A0A1L1RVT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 248", "type": "synonym", "evidence": [ { "id": "XP_024997905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997905" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997905" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVT9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM248", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9", "locus": { "chromosome": "19", "start_pos": 5556599, "end_pos": 5541613, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029673", "url": "https://www.ensembl.org/id/ENSGALG00010029673" } ] } } ], "crossref": [ { "id": "A0A1L1RVT9", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RVT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033954", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417549", "url": "https://www.ncbi.nlm.nih.gov/gene/417549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039493", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039493", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417549", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLFCYAI", "url": "https://omabrowser.org/oma/group/TLFCYAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RVT9", "url": "https://www.orthodb.org/?gene=A0A1L1RVT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16002:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16002:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14940", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14940", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RVT9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RVT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNINLLENLKVYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMTEDWNTFLLRFNDLDFCISENETLKHLINDTTTPESTVTSGQARSSTQSPQTLEDSGPINISVTITLTLDPLRPFGGYSRNITHLSSTIFGHQIGLSGRESHEEINITFTLPAAWNSDDCVLHGHCEQVVFTTCMTVTAASNVFPVTVQPPHCVPETYSNATLWYKIFTTARDSNTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNTEFCSEKVALSEA", "length": 314, "header": "tr|A0A1L1RVT9-1|A0A1L1RVT9_CHICK Isoform 1 of Transmembrane protein 248 OS=Gallus gallus OX=9031 GN=TMEM248 PE=3 SV=2 CANONICAL=A0A1L1RVT9-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RVT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9/entry", "sequence": { "sequence": "MVNINLLENLKVYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMTEDWNTFLLRFNDLDFCISENETLKHLINDTTTPESTVTSGQARSSTQSPQTLEDSGPINISVTITLTLDPLRPFGGYSRNITHLSSTIFGHQIGLSGRESHEEINITFTLPAAWNSDDCVLHGHCEQVVFTTCMTVTAASNVFPVTVQPPHCVPETYSNATLWYKIFTTARDSNTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNTEFCSEKVALSEA", "length": 314, "header": "tr|A0A1L1RVT9-1|A0A1L1RVT9_CHICK Isoform 1 of Transmembrane protein 248 OS=Gallus gallus OX=9031 GN=TMEM248 PE=3 SV=2 CANONICAL=A0A1L1RVT9-1" }, "locus": { "chromosome": "19", "start_pos": 5553877, "end_pos": 5548953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071769.1", "url": "https://www.ensembl.org/id/ENSGALT00010071769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044459.1", "url": "https://www.ensembl.org/id/ENSGALP00010044459.1" } ] } }, { "isoform_ac": "A0A8V1AJX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX8/entry", "sequence": { "sequence": "MVNINLLENLKVYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMTEDWNTFLLRFNDLDFCISENETLKHLINDTTTPESTVTSGQARSSTQSPQTLEDSGPINISVTITLTLDPLRPFGGYSRNITHLSSTIFGHQIGLSGRESHEEINITFTLPAAWNSDDCVLHGHCEQVVFTTCMTVTAASNVFPVTVQPPHCVPETYSNATLWYKIFTTARDSNTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDVIIKGRPSKLRQSNTEFCSEKVALSEA", "length": 287, "header": "tr|A0A8V1AJX8-1|A0A1L1RVT9_CHICK Computationally mapped isoform of Transmembrane protein 248 OS=Gallus gallus OX=9031 GN=TMEM248 PE=3 SV=1 CANONICAL=A0A1L1RVT9-1" }, "locus": { "chromosome": "19", "start_pos": 5553877, "end_pos": 5548953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071768.1", "url": "https://www.ensembl.org/id/ENSGALT00010071768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044458.1", "url": "https://www.ensembl.org/id/ENSGALP00010044458.1" } ] } }, { "isoform_ac": "A0A8V1ALL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL8/entry", "sequence": { "sequence": "MVNINLLENLKVYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMTEDWNTFLLRFNDLDFCISENETLKHLINDTTTPESTVTSGQARSSTQSPQTLEDSGPINISVTITLTLDPLRPFGGYSRNITHLSSTIFGHQIGLSGRESHEEINITFTLPAAWNSDDCVLHGHCEQVVFTTCMTVTAASNVFPVTVQPPHCVPETYSNATLWYKIFTTARDSNTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNTEFCSEKVSLSIIHPLTLLRMTENRNHCLLNPEWVLTLCEYIILQCWFIPTKDISSACN", "length": 360, "header": "tr|A0A8V1ALL8-1|A0A1L1RVT9_CHICK Computationally mapped isoform of Transmembrane protein 248 OS=Gallus gallus OX=9031 GN=TMEM248 PE=3 SV=1 CANONICAL=A0A1L1RVT9-1" }, "locus": { "chromosome": "19", "start_pos": 5554020, "end_pos": 5548953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071770.1", "url": "https://www.ensembl.org/id/ENSGALT00010071770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044460.1", "url": "https://www.ensembl.org/id/ENSGALP00010044460.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417549", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417549", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJI0-1", "protein_name": "Transmembrane protein 248", "gene_name": "TMEM248", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRIMFSINPLENLKLYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMAEDWNTFLLRFNDLDLCVSENETLKHLTNDTTTPESTMTSGQARTSTQSPQSLEDSGPVNISVAITLTLDPLKPFGGYSRNVTHLYSTILGHQIGLSGREAHEEINITFTLPTAWSSDDCALHAHCEQVVFTACMTLTANPGVFPVTVQPPHCVPDTYSNATLWYKIFTTARDANTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNPEFCPEKVALADA", "length": 317 }, "evidence": [ { "id": "A0A1L1RVT9", "url": "https://omabrowser.org/oma/group/A0A1L1RVT9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2YDM0-1", "protein_name": "Transmembrane protein 248", "gene_name": "TMEM248", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFNINPLENLKLYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMAEDWNTFLLRFNDLDLCVSENETLKHLTNDTAAPESTVTSGQARTSTQSPQPLEDAGPVNISVAITLTLDPLKPFGGYSRNVTHLYSTILGHQIGLSGREAQEEINITFTLPTSWSSDDCALHGHCEQVVFTACMTLTAHPGVFPVTVQPPHCVPDTYSNATLWYKIFTTARDANTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNPEFCPEKVALADA", "length": 314 }, "evidence": [ { "id": "A0A1L1RVT9", "url": "https://omabrowser.org/oma/group/A0A1L1RVT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TBN1-1", "protein_name": "Transmembrane protein 248", "gene_name": "Tmem248", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSINPLENLKLYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMAEDWNTFLLRFNDLDLCVSENETLKHLSNDTTTPESTMTVGQARSSTQPPQSLEESGPINISVAITLTLDPLKPFGGYSRNVTHLYSTILGHQIGLSGREAHEEINITFTLPAAWNADDCALHGHCEQAVFTACMTLTAAPGVFPVTVQPPHCIPDTYSNATLWYKIFTTARDANTKYAQDYNPFWCYKGAIGKVYHALNPKLTVVVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNPEFCPEKVALADA", "length": 314 }, "evidence": [ { "id": "A0A1L1RVT9", "url": "https://omabrowser.org/oma/group/A0A1L1RVT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AY76-1", "protein_name": "Transmembrane protein 248", "gene_name": "Tmem248", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSINPLENLKLYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMAEDWNTFLLRFNDLDLCVSENETLKHLSNDTTTPESTMTIGQTRSSTQPPQSLEESGPINISVAITLTLDPLKPFGGYSRNVTHLYSTILGHQIGLSGREAHEEINITFTLPAAWNADDCALHGHCEQVVFTACMTLTAAPGVFPVTVQPPHCVPDTYSNATLWYKIFTTARDANTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNPEFCPEKVALADA", "length": 314 }, "evidence": [ { "id": "A0A1L1RVT9", "url": "https://omabrowser.org/oma/group/A0A1L1RVT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NWD8-1", "protein_name": "Transmembrane protein 248", "gene_name": "TMEM248", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSINPLENLKVYISSRPPLVVFMISVSAMAIAFLTLGYFFKIKEIKSPEMAEDWNTFLLRFNDLDLCVSENETLKHLTNDTTTPESTMTSGQARASTQSPQALEDSGPVNISVSITLTLDPLKPFGGYSRNVTHLYSTILGHQIGLSGREAHEEINITFTLPTAWSSDDCALHGHCEQVVFTACMTLTASPGVFPVTVQPPHCVPDTYSNATLWYKIFTTARDANTKYAQDYNPFWCYKGAIGKVYHALNPKLTVIVPDDDRSLINLHLMHTSYFLFVMVITMFCYAVIKGRPSKLRQSNPEFCPEKVALAEA", "length": 314 }, "evidence": [ { "id": "A0A1L1RVT9", "url": "https://omabrowser.org/oma/group/A0A1L1RVT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVT9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RVT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVT9" }, { "id": "PF14940", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14940" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM248/TMEM219", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 257, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RWS8-1", "uniprot_ac": "A0A1L1RWS8", "uniprot_id": "A0A1L1RWS8_CHICK", "mass": { "chemical_mass": 53711.0, "monoisotopic_mass": 53711.0 }, "refseq": { "ac": "XP_025011235", "name": "coronin-1C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235" }, "gene_names": [ { "name": "CORO1C", "type": "recommended", "evidence": [ { "id": "A0A1L1RWS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ] }, { "name": "CORO1C", "type": "synonym", "evidence": [ { "id": "XP_025011235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235" } ] }, { "name": "coronin-1C", "type": "synonym", "evidence": [ { "id": "XP_025011235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "A0A1L1RWS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8/entry#names_and_taxonomy" } ] }, { "name": "coronin-1C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025011235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CORO1C", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8", "locus": { "chromosome": "15", "start_pos": 6533527, "end_pos": 6589529, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022497", "url": "https://www.ensembl.org/id/ENSGALG00010022497" } ] } } ], "crossref": [ { "id": "A0A1L1RWS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RWS8", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWS8", "url": "https://www.orthodb.org/?gene=A0A1L1RWS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR80", "url": "https://www.orthodb.org/?gene=A0A8V0ZR80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025011235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011235", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKVRIIDPRKQEIIAEKEKTHEGARPMRAIFLADGNIFTTGFSRMSERQLALWNPKNMEEPIALHEMDTSNGVLLPFYDPDTNIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGFMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPLLISLKHGYIPGKNRDLKVVKKNILDNKPAANKKSDLISAPKKAADASDTQNEAKLDEILKELKSIKDTITNQDERISKLEQQMAKIAD", "length": 478, "header": "tr|A0A1L1RWS8-1|A0A1L1RWS8_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8/entry", "sequence": { "sequence": "MRDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKVRIIDPRKQEIIAEKEKTHEGARPMRAIFLADGNIFTTGFSRMSERQLALWNPKNMEEPIALHEMDTSNGVLLPFYDPDTNIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGFMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPLLISLKHGYIPGKNRDLKVVKKNILDNKPAANKKSDLISAPKKAADASDTQNEAKLDEILKELKSIKDTITNQDERISKLEQQMAKIAD", "length": 478, "header": "tr|A0A1L1RWS8-1|A0A1L1RWS8_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "locus": { "chromosome": "15", "start_pos": 6571733, "end_pos": 6551537, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054753.1", "url": "https://www.ensembl.org/id/ENSGALT00010054753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033090.1", "url": "https://www.ensembl.org/id/ENSGALP00010033090.1" } ] } }, { "isoform_ac": "A0A8V0ZIE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE4/entry", "sequence": { "sequence": "MCACRAQWEAGSPGLVASPWQHFARTKLCKGSGDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKVRIIDPRKQEIIAEKEKTHEGARPMRAIFLADGNIFTTGFSRMSERQLALWNPKNMEEPIALHEMDTSNGVLLPFYDPDTNIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGFMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPLLISLKHGYIPGKNRDLKVVKKNILDNKPAANKKSDLISAPKKAADASDTQNEAKLDEILKELKSIKDTITNQDERISKLEQQMAKIAD", "length": 509, "header": "tr|A0A8V0ZIE4-1|A0A8V0ZIE4_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "locus": { "chromosome": "15", "start_pos": 6589429, "end_pos": 6551537, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054773.1", "url": "https://www.ensembl.org/id/ENSGALT00010054773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033103.1", "url": "https://www.ensembl.org/id/ENSGALP00010033103.1" } ] } }, { "isoform_ac": "A0A8V0ZNQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ5/entry", "sequence": { "sequence": "MRDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKLEKKPSFSLVRIG", "length": 214, "header": "tr|A0A8V0ZNQ5-1|A0A8V0ZNQ5_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "locus": { "chromosome": "15", "start_pos": 6571733, "end_pos": 6555006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054747.1", "url": "https://www.ensembl.org/id/ENSGALT00010054747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033085.1", "url": "https://www.ensembl.org/id/ENSGALP00010033085.1" } ] } }, { "isoform_ac": "A0A8V0ZQJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ0/entry", "sequence": { "sequence": "MQQCVTLHCVAVVLGDSKVTSPWLCPLTSSRCLRVADHPLPFLCSTDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKVRIIDPRKQEIIAEKEKTHEGARPMRAIFLADGNIFTTGFSRMSERQLALWNPKNMEEPIALHEMDTSNGVLLPFYDPDTNIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGFMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPLLISLKHGYIPGKNRDLKVVKKNILDNKPAANKKSDLISAPKKAADASDTQNEAKLDEILKELKSIKDTITNQDERISKLEQQMAKIAD", "length": 522, "header": "tr|A0A8V0ZQJ0-1|A0A8V0ZQJ0_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "locus": { "chromosome": "15", "start_pos": 6568096, "end_pos": 6551537, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054763.1", "url": "https://www.ensembl.org/id/ENSGALT00010054763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033097.1", "url": "https://www.ensembl.org/id/ENSGALP00010033097.1" } ] } }, { "isoform_ac": "A0A8V0ZR80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR80/entry", "sequence": { "sequence": "MAASTWQSCGYLRDDTSQARGTDCATSRGGSAVARQECSLQPRQQGLGATIRAHGPAMSSAGMEGESPPKVYEMQVGQQWAGSGRTVRPVVYRLEESEYRRLLKEAEEGPEEDWEPENEGLGPQEGCSGNGVTASPRLHRIDVLRGAPLIRSYSESSVELRVASKAPGCPTEGGKPRVPARSDSFELMDYILQSRQEAGAPLSHSPRDGFMQVLGFAPCQNGEDGQLTKSRAARDAGKLTRQNSTQVPESSEWLGADVDMEMLESYSQKKSPPAPPVRSHSKESLALSMSKTVALSEALLEPCGPAARPGGKEPTGGGLKEQGRKSEEEEEEEEEKVLKVADAKKTFEKAKAEGKAAASSARKDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIVDASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVVLEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHVDVIYNVSWNRNGSLICTASKDKKVRIIDPRKQEIIAEKEKTHEGARPMRAIFLADGNIFTTGFSRMSERQLALWNPKNMEEPIALHEMDTSNGVLLPFYDPDTNIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGFMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPLLISLKHGYIPGKNRDLKVVKKNILDNKPAANKKSDLISAPKKAADASDTQNEAKLDEILKELKSIKDTITNQDERISKLEQQMAKIAD", "length": 839, "header": "tr|A0A8V0ZR80-1|A0A1L1RWS8_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO1C PE=1 SV=1 CANONICAL=A0A1L1RWS8-1" }, "locus": { "chromosome": "15", "start_pos": 6588139, "end_pos": 6551537, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054768.1", "url": "https://www.ensembl.org/id/ENSGALT00010054768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033101.1", "url": "https://www.ensembl.org/id/ENSGALP00010033101.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWS8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TU24-1", "uniprot_ac": "A0A3Q2TU24", "uniprot_id": "A0A3Q2TU24_CHICK", "mass": { "chemical_mass": 22618.0, "monoisotopic_mass": 22618.0 }, "refseq": {}, "gene_names": [ { "name": "PDGFA", "type": "recommended", "evidence": [ { "id": "A0A3Q2TU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU24" } ] } ], "protein_names": [ { "name": "Platelet-derived growth factor subunit A", "type": "recommended", "evidence": [ { "id": "A0A3Q2TU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU24/entry#names_and_taxonomy" } ] }, { "name": "Platelet-derived growth factor A chain", "type": "synonym", "evidence": [ { "id": "A0A3Q2TU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU24/entry#names_and_taxonomy" } ] }, { "name": "Platelet-derived growth 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"Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TWZ8-1", "uniprot_ac": "A0A3Q2TWZ8", "uniprot_id": "A0A3Q2TWZ8_CHICK", "mass": { "chemical_mass": 89596.0, "monoisotopic_mass": 89596.0 }, "refseq": { "ac": "XP_015145089", "name": "mitogen-activated protein kinase kinase kinase 20 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145089" }, "gene_names": [ { "name": "MAP3K20", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "name": "MAP3K20", "type": "synonym", "evidence": [ { "id": "XP_015145089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145089" } ] } ], "protein_names": [ { "name": "Mitogen-activated protein kinase kinase kinase 20", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.25", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "Leucine zipper- and sterile alpha motif-containing kinase", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "MLK-like mitogen-activated protein triple kinase", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "Mitogen-activated protein kinase kinase kinase MLT", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "Mixed lineage kinase-related kinase", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "Sterile alpha motif- and leucine zipper-containing kinase AZK", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase kinase kinase 20 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015145089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145089" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145089" } ] }, { "annotation": "Isoform that lacks the C-terminal region that mediates ribosome-binding: does not act as a sensor of ribosome collisions in response to ribotoxic stress. May act as an antagonist of isoform ZAKalpha: interacts with isoform ZAKalpha, leading to decrease the expression of isoform ZAKalpha.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8#function" }, { "database": "UniProtKB", "id": "ARBA00056730", "url": "https://www.uniprot.org/uniprotkb/ARBA00056730#function" } ] }, { "annotation": "Stress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to various stress, such as ribosomal stress, osmotic shock and ionizing radiation. Acts by catalyzing phosphorylation of MAP kinase kinases, leading to activation of the JNK (MAPK8/JNK1, MAPK9/JNK2 and/or MAPK10/JNK3) and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways. Activates JNK through phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7, and MAP kinase p38 gamma (MAPK12) via phosphorylation of MAP2K3/MKK3 and MAP2K6/MKK6. Involved in stress associated with adrenergic stimulation: contributes to cardiac decompensation during periods of acute cardiac stress. May be involved in regulation of S and G2 cell cycle checkpoint by mediating phosphorylation of CHEK2.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8#function" }, { "database": "UniProtKB", "id": "ARBA00058083", "url": "https://www.uniprot.org/uniprotkb/ARBA00058083#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP3K20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TWZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035237", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035237", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424149", "url": "https://www.ncbi.nlm.nih.gov/gene/424149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424149", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEMSCQI", "url": "https://omabrowser.org/oma/group/TEMSCQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TWZ8", "url": "https://www.orthodb.org/?gene=A0A3Q2TWZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5P7", "url": "https://www.orthodb.org/?gene=A0A3Q2U5P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK76", "url": "https://www.orthodb.org/?gene=A0A8V0ZK76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329:SF288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329:SF288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5P7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSTSASFVQIRFDDLQFFENCGGGSFGSVYRARWISQDKEVAVKKLLKIEKEAEILSVLSHKNIIQFYGAVIEPPNYGIVTEYASAGSLFDYINSNKSEEMDMDHIMTWATDIAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHSHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELMHQCWEADSKKRPSFKQIISILESMSNDSNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFDICAWTEEDVFFWMQQLTRKGDASGEMSAYASLFKEHHITGKRLLLLEEEDLKDMGIISRGHIIHLKTAIEKLTHDYLNLFHFPPLIKDSAGEAEENIEKVVNLELVFGYHLKLGNGPKDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDVEILKMTKPPFVMEKWIVGIEEHQSVECIVTYESDVRAPKSTRHVQAICWSKVKAQDEVKAVQLMIQTSLPNSEGHSRSRSVSSIDSQWMQTLRMHQIAKAISLQHGDPHSPTTVSHYLPYLQSQDSYAAAVRRTRGPVNYHYTSISHSRNSSPLSHSLVRNLSSLHINSKGSSTSSTASDTASERDRSTGKARNASHSGNSRSSSDGRRSGTSSPVPPRSSGRAGRTASMPPAHEQRRYPRNSPQPKAIPGMPLQGESEPRRSEGEGRASEGGWIKVQHVKKPHRQSTGKQGKERPKGSWRGRRAF", "length": 791, "header": "tr|A0A3Q2TWZ8-1|A0A3Q2TWZ8_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 20 OS=Gallus gallus OX=9031 GN=MAP3K20 PE=3 SV=1 CANONICAL=A0A3Q2TWZ8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8/entry", "sequence": { "sequence": "MSSTSASFVQIRFDDLQFFENCGGGSFGSVYRARWISQDKEVAVKKLLKIEKEAEILSVLSHKNIIQFYGAVIEPPNYGIVTEYASAGSLFDYINSNKSEEMDMDHIMTWATDIAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHSHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELMHQCWEADSKKRPSFKQIISILESMSNDSNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFDICAWTEEDVFFWMQQLTRKGDASGEMSAYASLFKEHHITGKRLLLLEEEDLKDMGIISRGHIIHLKTAIEKLTHDYLNLFHFPPLIKDSAGEAEENIEKVVNLELVFGYHLKLGNGPKDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDVEILKMTKPPFVMEKWIVGIEEHQSVECIVTYESDVRAPKSTRHVQAICWSKVKAQDEVKAVQLMIQTSLPNSEGHSRSRSVSSIDSQWMQTLRMHQIAKAISLQHGDPHSPTTVSHYLPYLQSQDSYAAAVRRTRGPVNYHYTSISHSRNSSPLSHSLVRNLSSLHINSKGSSTSSTASDTASERDRSTGKARNASHSGNSRSSSDGRRSGTSSPVPPRSSGRAGRTASMPPAHEQRRYPRNSPQPKAIPGMPLQGESEPRRSEGEGRASEGGWIKVQHVKKPHRQSTGKQGKERPKGSWRGRRAF", "length": 791, "header": "tr|A0A3Q2TWZ8-1|A0A3Q2TWZ8_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 20 OS=Gallus gallus OX=9031 GN=MAP3K20 PE=3 SV=1 CANONICAL=A0A3Q2TWZ8-1" }, "locus": { "chromosome": "7", "start_pos": 17048718, "end_pos": 16970564, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052893.1", "url": "https://www.ensembl.org/id/ENSGALT00010052893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031799.1", "url": "https://www.ensembl.org/id/ENSGALP00010031799.1" } ] } }, { "isoform_ac": "A0A3Q2U5P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5P7/entry", "sequence": { "sequence": "MSSTSASFVQIRFDDLQFFENCGGGSFGSVYRARWISQDKEVAVKKLLKIEKEAEILSVLSHKNIIQFYGAVIEPPNYGIVTEYASAGSLFDYINSNKSEEMDMDHIMTWATDIAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHSHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELMHQCWEADSKKRPSFKQIISILESMSNDSNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLYIIWKTSLGILSASCNPWSQVSPSVPQFRFLLPLAARMSEESYFESKTEESKSAEMSCQITATSNGEVAGMNQSLKALMMTGFGDIFSLNQAGSVLRSGMQINMQAKKNSSKTTSMRKGKKINMALGFSEFDWSDDDDDDDDFDDTDDSSE", "length": 481, "header": "tr|A0A3Q2U5P7-1|A0A3Q2U5P7_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 20 OS=Gallus gallus OX=9031 GN=MAP3K20 PE=4 SV=1 CANONICAL=A0A3Q2TWZ8-1" }, "locus": { "chromosome": "7", "start_pos": 17048718, "end_pos": 16996846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052890.1", "url": "https://www.ensembl.org/id/ENSGALT00010052890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031796.1", "url": "https://www.ensembl.org/id/ENSGALP00010031796.1" } ] } }, { "isoform_ac": "A0A8V0ZK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK76/entry", "sequence": { "sequence": "MLSRFLLQCACRNRFRCGIFCHYEMSSTSASFVQIRFDDLQFFENCGGGSFGSVYRARWISQDKEVAVKKLLKIEKEAEILSVLSHKNIIQFYGAVIEPPNYGIVTEYASAGSLFDYINSNKSEEMDMDHIMTWATDIAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHSHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELMHQCWEADSKKRPSFKQIISILESMSNDSNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPFLLPLAARMSEESYFESKTEESKSAEMSCQITATSNGEVAGMNQSLKALMMTGFGDIFSLNQAGSVLRSGMQINMQAKKNSSKTTSMRKGKKINMALGFSEFDWSDDDDDDDDFDDTDDSSE", "length": 475, "header": "tr|A0A8V0ZK76-1|A0A3Q2TWZ8_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 20 OS=Gallus gallus OX=9031 GN=MAP3K20 PE=3 SV=1 CANONICAL=A0A3Q2TWZ8-1" }, "locus": { "chromosome": "7", "start_pos": 17048877, "end_pos": 16996846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052888.1", "url": "https://www.ensembl.org/id/ENSGALT00010052888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031794.1", "url": "https://www.ensembl.org/id/ENSGALP00010031794.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424149", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LH95-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "MAP3K20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLGTSFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSLDSKLSDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYFWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIISKGHIIHLKSAIEKLTHDYLNLFHFPPLIKGSVGEPEENEEKIVNLELVFGFHLKPGTGLQDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDAEILKMTKPPFVMEKWIVGIVENQTVECTVTYESDVRTPKSTKHIHSIQWSRMKPQDEVKAVQLAIQTLFPNSEGTPGSRSDSNADCQWLDTLRMRQIASNTSLQRSQSNPILASQFFPYFNDQDSYAAAVRRTQVPIKYQQITPINQSRSSSPTQYGLTKNFSSLHLNSRDSGFSSVNTDSSLERGQYSGRSRNKYDRASHSLNSSPRGRHSGKSQHSTPSRERYSGKFYRVSRSALNAHQSPDFKRSPDASHQPRTIPGMPLCTDMDSRANEEESKVSEGGWTKVEYRKKPHRPSPAKSNRERPRGNFRGRRNF", "length": 800 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A5G2QJ76-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "MAP3K20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLGTSFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADPKKRPSFKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYFWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHLKSAIEKLTHDYLNLFHFPPLIKDSVGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDAEILKMTKPPFVMEKWIIGILENQTVECTVTYESDVRTPKSTKHVHSIKWSKTKPQDEVKAVQLAIQTSFSNSEGNPRSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSQFFPYFHDPDSYAAAVRRTQVPIKYQQITPINQSRSSSPTQYALTKHFSSLHLNSKDSSFSSLNSNSLERGRYSGRSRNKYDRGSVSLNSSPRGRYGGKSQHSTPSRERYSGKFYRVSQSALNTHSSPDLKRSPNDSQQPRTIPGMPLRFDTESRASEEESKVSEGGWTRVEYRKKPHRPSPAKTNRERPRGTYRGKRNF", "length": 799 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M4R2-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "Map3k20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSLGTSFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEISAWTEDDVYFWVQQLVRKGDSSVEMSGYASLFKENNITGKRLLLLDEEDLKDMGIVSKGHIIHFKSAIEKLAHDYLNLFHFPPLIKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNTSLPDAEILKMTKPPFVMEKWIIGIVANQTVECMVTYESDVRTPKLTKHVHSIQWSKTKPQDEVKAVQLAIQTVFSNSDGNPGSRSDSSADCQWLDTLRLRQIASHTTLQRSQSNPILGSPFFPYFANQDSYAAAVRRTQTPVKYQQITPINPSRSSSPTQYGLTKNFSSLHLNSRDSGFSSLNTDSSSERGRYSDRYSDRSRNKYSRGSVSLNSSPRGRYGGGRSQHSAPSRERYSGKFYRFPQSALNTHQSPDFKKNPNDRRVPRTIPGMPLHPEAVSRAGEEESRVSEGGWTKVEYRKKTHRQLPAKTSKERTRGNYRGRRNF", "length": 805 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AE17-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "Map3k20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNVIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEEDVYFWVQQLVGKGESSVEMSGYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYLNLFHFPPLIKDSGEEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEVAIAYIKDVTFNTSLPDAEILKMTKPPFVMEKWIVGIVKDQTVECTVTYESDVRTPKFTKHVHSIQWDRAKPQDEVKAVQLAIQTLFSSSEGNPGSRSDSSADCQWLDTLRMRQIASHSSLQRSQSNPILGSPFFQYFVNQDSYAAAVRRTQTPVKYQQITPSINPSRSSSPTQYGLTKNFSSLHLNSRDSGFSSLNDSSSERGRYSDRSRNKYYRGSVSLNSSPKGRYGGKSQHSTPSRERYPGKFYRLPQSALNTHQSPDFKRSPNDHDRRAPKTIPGMPLHPETAPKAGEEESRVSEGGWTKVEYRKKTHRQLSAKTSKDRTRGNYRGRRNF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESL4-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "Map3k20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYFWVQQLVRKGESSVEMSGYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYLNLFHFPPLIKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEVAITYIKDVTFNTSLPDAEILKMTKPPFVMEKWIVGIAEDQTVECTVTYENDVRTPKLTKHVHSIQWDRTKPQDEVKAVQLAIQTLFSSSEGNPGSRSDSSADCQWLDTLRMRQIASHTSLQRSQSNPILGSPFFPYFANQDSYAAAVRRTQTPVKYQQITPSINPSRSSSPTQYGLSRNFSSLNLSSRDSGFSSLNDSSSERGRYSDRSRNKYYRGSVSLNSSPKGRYGGKSQHSTPSRERYSGKFYRLPQSALNTHQSPDFKRSPNDHDRRVPRTIPGMPLHPETASKAGEEESRVSEGGWTKVEYRKKTHRQLSAKTSKERTRGNYRGRRNF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYL2-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "MAP3K20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPLIKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKPQDEVKAVQLAIQTLFTNSDGNPGSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSPFFSHFDGQDSYAAAVRRPQVPIKYQQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFSSGNTDTSSERGRYSDRSRNKYGRGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQSALNPHQSPDFKRSPRDLHQPNTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRPSPAKTNKERARGDHRGWRNF", "length": 800 }, "evidence": [ { "id": "A0A3Q2TWZ8", "url": "https://omabrowser.org/oma/group/A0A3Q2TWZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", 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"url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TWZ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 791, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TWZ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWZ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.25", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.25", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25" }, { "id": "2.7.11.25", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.25" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW3#function" }, { "database": "UniProtKB", "id": "ARBA00037467", "url": "https://www.uniprot.org/uniprotkb/ARBA00037467#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSME3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3", "locus": { "chromosome": "27", "start_pos": 5065866, "end_pos": 5058598, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022317", "url": "https://www.ensembl.org/id/ENSGALG00010022317" } ] } } ], "crossref": [ { "id": "A0A1L1RUZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RUZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002937", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RUZ3", "url": "https://www.orthodb.org/?gene=A0A1L1RUZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHJ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10660", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10660", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10660:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10660:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9907900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RUZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSRSRILKEVSSFSGWLQRWHTKLTCVVQAGARPPSMPCLSTPLSPEPAPPPSPPPDVTHRPARSYQECRSPSGGHFLFHVPLYFLPASCQDPAAWSGGERTSCYWRVRCVTSLPAAAEPVAVVGWAAGAARGTARPGFAPAAMASLLKVDPEVKLKVDSFRERITSEAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDREETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYEGTESLLGVLLGKVTFWGRSSSFAGAGCVWKKCGTVSLICSLHFPNRYYITRAKLVSKIAKYPHVVSKWGSGALQFTCCCFLGTLRATSSLFFLS", "length": 421, "header": "tr|A0A1L1RUZ3-1|A0A1L1RUZ3_CHICK Isoform 1 of Proteasome activator complex subunit 3 OS=Gallus gallus OX=9031 GN=PSME3 PE=3 SV=2 CANONICAL=A0A1L1RUZ3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RUZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3/entry", "sequence": { "sequence": "MVSRSRILKEVSSFSGWLQRWHTKLTCVVQAGARPPSMPCLSTPLSPEPAPPPSPPPDVTHRPARSYQECRSPSGGHFLFHVPLYFLPASCQDPAAWSGGERTSCYWRVRCVTSLPAAAEPVAVVGWAAGAARGTARPGFAPAAMASLLKVDPEVKLKVDSFRERITSEAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDREETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYEGTESLLGVLLGKVTFWGRSSSFAGAGCVWKKCGTVSLICSLHFPNRYYITRAKLVSKIAKYPHVVSKWGSGALQFTCCCFLGTLRATSSLFFLS", "length": 421, "header": "tr|A0A1L1RUZ3-1|A0A1L1RUZ3_CHICK Isoform 1 of Proteasome activator complex subunit 3 OS=Gallus gallus OX=9031 GN=PSME3 PE=3 SV=2 CANONICAL=A0A1L1RUZ3-1" }, "locus": { "chromosome": "27", "start_pos": 5063324, "end_pos": 5058797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054320.1", "url": "https://www.ensembl.org/id/ENSGALT00010054320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032809.1", "url": "https://www.ensembl.org/id/ENSGALP00010032809.1" } ] } }, { "isoform_ac": "A0A8V0ZHJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ9/entry", "sequence": { "sequence": "MASLLKVDPEVKLKVRLLLLAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDREETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 249, "header": "tr|A0A8V0ZHJ9-1|A0A8V0ZHJ9_CHICK Computationally mapped isoform of Proteasome activator complex subunit 3 OS=Gallus gallus OX=9031 GN=PSME3 PE=3 SV=1 CANONICAL=A0A1L1RUZ3-1" }, "locus": { "chromosome": "27", "start_pos": 5064185, "end_pos": 5059229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054304.1", "url": "https://www.ensembl.org/id/ENSGALT00010054304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032795.1", "url": "https://www.ensembl.org/id/ENSGALP00010032795.1" } ] } }, { "isoform_ac": "A0A8V0ZMW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW3/entry", "sequence": { "sequence": "MASLLKVDPEVKLKVDSFRERITSEAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDREETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 230, "header": "tr|A0A8V0ZMW3-1|A0A8V0ZMW3_CHICK Computationally mapped isoform of Proteasome activator complex subunit 1 OS=Gallus gallus OX=9031 GN=PSME3 PE=3 SV=1 CANONICAL=A0A1L1RUZ3-1" }, "locus": { "chromosome": "27", "start_pos": 5064185, "end_pos": 5059229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054311.1", "url": "https://www.ensembl.org/id/ENSGALT00010054311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032802.1", "url": "https://www.ensembl.org/id/ENSGALP00010032802.1" } ] } }, { "isoform_ac": "A0A8V0ZPP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP1/entry", "sequence": { "sequence": "MVSRSRILKEVSSFSGWLQRWHTKLTCVVQAGARPPSMPCLSTPLSPEPAPPPSPPPDVTHRPARSYQECRSPSGGHFLFHVPLYFLPASCQDPAAWSGGERTSCYWRVRCVTSLPAAAEPVAVVGWAAGAARGTARPGFAPAAMASLLKVDPEVKLKVDSFRERITSEAEDLVANFFPKKLLELDGFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPNMKKRKLEDREETFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY", "length": 398, "header": "tr|A0A8V0ZPP1-1|A0A1L1RUZ3_CHICK Computationally mapped isoform of Proteasome activator complex subunit 3 OS=Gallus gallus OX=9031 GN=PSME3 PE=3 SV=1 CANONICAL=A0A1L1RUZ3-1" }, "locus": { "chromosome": "27", "start_pos": 5064185, "end_pos": 5058797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054308.1", "url": "https://www.ensembl.org/id/ENSGALT00010054308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032799.1", "url": "https://www.ensembl.org/id/ENSGALP00010032799.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 377, "start_aa": "Thr", "end_pos": 377, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr377", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "proteasome activator complex", "id": "GO:0008537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008537", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "endopeptidase activator activity", "id": "GO:0061133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061133", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUZ3", "url": 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"https://www.uniprot.org/uniprotkb/Q5ZJD9/entry#names_and_taxonomy" } ] }, { "name": "OB-RGRP", "type": "synonym", "evidence": [ { "id": "Q5ZJD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9/entry#names_and_taxonomy" } ] }, { "name": "endospanin-1", "type": "synonym", "evidence": [ { "id": "NP_001007959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007959" } ] }, { "name": "leptin receptor gene-related protein", "type": "synonym", "evidence": [ { "id": "NP_001007959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007959" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720495.1, SRR13267661.22349.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000239.1. On Dec 15, 2004 this sequence version replaced XP_422528.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007959", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007959" } ] }, { "annotation": "Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJD9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJD9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LEPROT", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9", "locus": { "chromosome": "8", "start_pos": 28010094, "end_pos": 28004253, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024151", "url": "https://www.ensembl.org/id/ENSGALG00010024151" } ] } } ], "crossref": [ { "id": "Q5ZJD9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011047", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011047", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424699", "url": "https://www.ncbi.nlm.nih.gov/gene/424699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424699", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSHVDMT", "url": "https://omabrowser.org/oma/group/RSHVDMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3M0", "url": "https://www.orthodb.org/?gene=A0A8V1A3M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJD9", "url": "https://www.orthodb.org/?gene=Q5ZJD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12050:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12050:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJD9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJD9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007959", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY8", "url": 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receptor gene-related protein OS=Gallus gallus OX=9031 GN=LEPROT PE=2 SV=1 CANONICAL=Q5ZJD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY8/entry", "sequence": { "sequence": "MAGIKALVGLSFSGAIGLTFLMLGCALEYYGVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAPGEPRASVNPPFTFLVMFLDSDENNHCWELAYAAF", "length": 128, "header": "tr|A0A8V0ZQY8-1|OBRG_CHICK Computationally mapped isoform of Leptin receptor gene-related protein OS=Gallus gallus OX=9031 GN=LEPROT PE=2 SV=1 CANONICAL=Q5ZJD9-1" }, "locus": { "chromosome": "8", "start_pos": 28005785, "end_pos": 28004354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058895.1", "url": "https://www.ensembl.org/id/ENSGALT00010058895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035860.1", "url": "https://www.ensembl.org/id/ENSGALP00010035860.1" } ] } }, { "isoform_ac": "A0A8V1A3M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M0/entry", "sequence": { "sequence": "MAGIKGTERCRRSALRLGAAGGRTEPLPAAVSCSVPASWRSGLVALPFPSAGPGGSGGRVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAIKWGACGLVLAGNAVIFLTILGFFLVFGRGDDFSWEQW", "length": 159, "header": "tr|A0A8V1A3M0-1|OBRG_CHICK Computationally mapped isoform of Leptin receptor gene-related protein OS=Gallus gallus OX=9031 GN=LEPROT PE=2 SV=1 CANONICAL=Q5ZJD9-1" }, "locus": { "chromosome": "8", "start_pos": 28006963, "end_pos": 28004354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058901.1", "url": "https://www.ensembl.org/id/ENSGALT00010058901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035866.1", "url": "https://www.ensembl.org/id/ENSGALP00010035866.1" } ] } }, { "isoform_ac": "Q5ZJD9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9/entry#Q5ZJD9-1", "sequence": { "sequence": "MAGIKALVGLSFSGAIGLTFLMLGCALEYYGVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAIKWGACGLVLAGNAVIFLTILGFFLVFGRGDDFSWEQW", "length": 131, "header": "sp|Q5ZJD9-1|OBRG_CHICK Isoform 1 of Leptin receptor gene-related protein OS=Gallus gallus OX=9031 GN=LEPROT PE=2 SV=1 CANONICAL=Q5ZJD9-1" }, "locus": { "chromosome": "8", "start_pos": 28006963, "end_pos": 28004354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058912.1", "url": "https://www.ensembl.org/id/ENSGALT00010058912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035877.1", "url": "https://www.ensembl.org/id/ENSGALP00010035877.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJD9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B9TRX0-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "LEPROT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLVFHALSPIPHFIAKRATYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HY61-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "Leprot", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15243-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "LEPROT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLIFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O89013-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "Leprot", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGLPVVLARVDVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SYT0-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "LEPROT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRATYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVSVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JLS8-1", "protein_name": "Leptin receptor gene-related protein", "gene_name": "Leprot", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW", "length": 131 }, "evidence": [ { "id": "Q5ZJD9", "url": "https://omabrowser.org/oma/group/Q5ZJD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of growth hormone receptor signaling pathway", "id": "GO:0060400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060400", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJD9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJD9" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body 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"recommended", "evidence": [ { "id": "Q5ZJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64/entry#names_and_taxonomy" } ] }, { "name": "PCI domain containing 1 (herpesvirus entry mediator)", "type": "synonym", "evidence": [ { "id": "NP_001006406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006406" } ] }, { "name": "eIF3m", "type": "synonym", "evidence": [ { "id": "Q5ZJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 3 subunit M", "type": "synonym", "evidence": [ { "id": "NP_001006406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006406" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720570.1, HAEL01013389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000212.1. On Jan 13, 2005 this sequence version replaced XP_419639.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006406" } ] }, { "annotation": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZW50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW50#function" }, { "database": "HAMAP", "id": "MF_03012", "url": "https://hamap.expasy.org/signature/MF_03012" }, { "database": "UniProtKB", "id": "A0A8V1A1M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M0#function" }, { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF3M", "url": 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"IPR027528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421602", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421602", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCLKALW", "url": "https://omabrowser.org/oma/group/VCLKALW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW50", "url": "https://www.orthodb.org/?gene=A0A8V0ZW50", "database": "OrthoDB", "categories": [ "Protein 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ64-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPAFIDITEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEVCDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLLKVASSCGAIQYIPTELDQVRKWISDWNLSTDKKHTLLRLLYDVLVDCKKSDTAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTFLFDHLLALKPVKFLEGELIHDLLTIFVSAKLVSYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVKTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNTWKQNLNQVKNSLLSLSDT", "length": 374, "header": "sp|Q5ZJ64-1|EIF3M_CHICK Isoform 1 of Eukaryotic translation initiation factor 3 subunit M OS=Gallus gallus OX=9031 GN=EIF3M PE=2 SV=1 CANONICAL=Q5ZJ64-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZW50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW50/entry", "sequence": { "sequence": "KSAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEVCDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLLKVASSCGAIQYIPTELDQVRKWISDWNLSTDKKHTLLRLLYDVLVDCKKSDTAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTFLFDHLLALKPVKFLEGELIHDLLTIFVSAKLVSYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVKTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNTWKQNLNQVKNSLLSLSDT", "length": 362, "header": "tr|A0A8V0ZW50-1|EIF3M_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit M OS=Gallus gallus OX=9031 GN=EIF3M PE=2 SV=1 CANONICAL=Q5ZJ64-1" }, "locus": { "chromosome": "5", "start_pos": 5734245, "end_pos": 5721261, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057825.1", "url": "https://www.ensembl.org/id/ENSGALT00010057825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035092.1", "url": "https://www.ensembl.org/id/ENSGALP00010035092.1" } ] } }, { "isoform_ac": "A0A8V1A1M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1M0/entry", "sequence": { "sequence": "MSVPAFIDITEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEVCDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLLKVASSCGAIQYIPTELDQVRKWISDWNLSTDKKHTLLRLLYDVLVDCKKSDTAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTFLFDHLLALKPVKFLEGELIHDLLTIFVSAKLVSYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVKTKMVYCKIDQTQRKVVVRLFPHFSFRFFCNDEVGDAMTTQCRKKTDGQQLTRNK", "length": 371, "header": "tr|A0A8V1A1M0-1|EIF3M_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit M OS=Gallus gallus OX=9031 GN=EIF3M PE=2 SV=1 CANONICAL=Q5ZJ64-1" }, "locus": { "chromosome": "5", "start_pos": 5759054, "end_pos": 5720150, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057819.1", "url": "https://www.ensembl.org/id/ENSGALT00010057819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035089.1", "url": "https://www.ensembl.org/id/ENSGALP00010035089.1" } ] } }, { "isoform_ac": "Q5ZJ64-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64/entry#Q5ZJ64-1", "sequence": { "sequence": "MSVPAFIDITEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEVCDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLLKVASSCGAIQYIPTELDQVRKWISDWNLSTDKKHTLLRLLYDVLVDCKKSDTAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTFLFDHLLALKPVKFLEGELIHDLLTIFVSAKLVSYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVKTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNTWKQNLNQVKNSLLSLSDT", "length": 374, "header": "sp|Q5ZJ64-1|EIF3M_CHICK Isoform 1 of Eukaryotic translation initiation factor 3 subunit M OS=Gallus gallus OX=9031 GN=EIF3M PE=2 SV=1 CANONICAL=Q5ZJ64-1" }, "locus": { "chromosome": "5", "start_pos": 5734245, "end_pos": 5720150, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057830.1", "url": "https://www.ensembl.org/id/ENSGALT00010057830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035095.1", "url": "https://www.ensembl.org/id/ENSGALP00010035095.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421602", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421602", "resource": "KEGG Pathway" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABZ3NNS0-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "EIF3M", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT", "length": 374 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZAZ0-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "Eif3m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWKLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLFKCKRVCGGYSGLPWS", "length": 366 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SGR0-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "EIF3M", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLNTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT", "length": 374 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54KZ8-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "eif3m", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIFIDLASLEDLYNDLISHIETLRKKKGSEYSVADYQILIGEQRTVEFLSKIVSNETEFLFKECKDSDKDIEGFFNVILTILHKLENEDEINIVSQKIRDSLSAHPTENSQLKIKILTNLFNSFQPKSTQRYDIFFALVKLASDSNNLEFVKYQITDIDSWLEDWNVSIQQKRKLYKLISNIFKEKQRMLSHQFLVKYLQTFTKEDSQEAQEDAVRVCIESISLQELYQSDYLLDLPAVQYLEGSTVSANSLTYELMKIFATEQLDSFLQFQQKNPNFLSTIGLSNDDCLQKIRLLSLATLTSEQSKVPYSLISKMLQIDENEVEMWVINAMEGDLLDAKLDQLNRIVNVNSSTQRVFNKSQWSQLGQRFSVWKSSVKNLLQVIENAKTTQVKPFYFQTR", "length": 401 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7JVI3-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "eIF3m", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSHPVFIDLSLDEQVQELRKYFKKLGAEISSEKSNKGVEDDLHKIIGVCDVCFKDGEPSQIDGILNSIVSIMITIPLDRGENIVLAYCEKMTKAPNLPLGKVCLQSLWRLFNNLDTASPLRYHVYYHLVQVAKQCEQVLEVFSGVDQLKSQFANCPPSSEQMQKLYRLLHDVTKDTNLELSSKVMIELLGTYTADNACVAREDAMKCIVTALADPNTFLLDPLLSLKPVRFLEGDLIHDLLSIFVSEKLPAYVQFYEDHREFVNSQGLNHEQNMKKMRLLTFMQLAESSPEMTFETLTKELQINEDEVEPFVIEVLKTKLVRARLDQANQKVHISSTMHRTFGAPQWEQLRDLLQAWKENLSTVREGLTSVSSAQLDLARSQKLIH", "length": 387 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7L2H7-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "EIF3M", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT", "length": 374 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7T3B0-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "eif3m", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVPAFIDITEEDQASELRSYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKDDDKDVESVMNSIVSLLLILETEKQEALIESLCEKLVKFREGERPSLRMQLLSNLFHGMDENTPVRHTVYCSLIKVAATCNAITFMPTDLDQVRKWIVDWNLNTEKKHTLLRLVYEALVDCKKSEAAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTYLFDHLLALKPVRFLEGELIHDLLTIFVSAKLISYVKFYQSNKDFIESLGLSHEQNMSKMRLLTFMGMAVEMKEISFETMQQELQIGAEDVEAFVIDAVRTKMVYSKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLCSWKQNLSTVKSSLQTLSPTA", "length": 375 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99JX4-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "Eif3m", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPAFIDISEEDQAAELRAYLKSKGAELSEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWKLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT", "length": 374 }, "evidence": [ { "id": "Q5ZJ64", "url": "https://omabrowser.org/oma/group/Q5ZJ64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex, eIF3m", "id": "GO:0071541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071541", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ64", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJ64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 374, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJ64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJ64" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ64" }, { "id": "PRU01185", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01185" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000255", "start_pos": 180, "end_pos": 339, "start_aa": "Thr", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], 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"evidence": [ { "id": "A0A3Q2TVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NETO2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9", "locus": { "chromosome": "11", "start_pos": 7331552, "end_pos": 7302635, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024340", "url": "https://www.ensembl.org/id/ENSGALG00010024340" } ] } } ], "crossref": [ { "id": "A0A3Q2TVY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TVY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004071", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004071", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415743", "url": "https://www.ncbi.nlm.nih.gov/gene/415743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P8L8", "url": "https://www.orthodb.org/?gene=A0A1D5P8L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TVY9", "url": "https://www.orthodb.org/?gene=A0A3Q2TVY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX49", "url": "https://www.orthodb.org/?gene=A0A8V0ZX49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX52", "url": "https://www.orthodb.org/?gene=A0A8V0ZX52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4L5", "url": "https://www.orthodb.org/?gene=A0A8V1A4L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P8L8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGGLVLLVTILVVEGIAVAQKTQGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 520, "header": "tr|A0A3Q2TVY9-1|A0A3Q2TVY9_CHICK Isoform 1 of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8L8/entry", "sequence": { "sequence": "MSSHVLLVTILVVEGIAVAQKTQGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 518, "header": "tr|A0A1D5P8L8-1|A0A3Q2TVY9_CHICK Computationally mapped isoform of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "locus": { "chromosome": "11", "start_pos": 7329417, "end_pos": 7304449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059367.1", "url": "https://www.ensembl.org/id/ENSGALT00010059367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036241.1", "url": "https://www.ensembl.org/id/ENSGALP00010036241.1" } ] } }, { "isoform_ac": "A0A3Q2TVY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9/entry", "sequence": { "sequence": "MARGGLVLLVTILVVEGIAVAQKTQGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 520, "header": "tr|A0A3Q2TVY9-1|A0A3Q2TVY9_CHICK Isoform 1 of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "locus": { "chromosome": "11", "start_pos": 7329417, "end_pos": 7302689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059361.1", "url": "https://www.ensembl.org/id/ENSGALT00010059361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036235.1", "url": "https://www.ensembl.org/id/ENSGALP00010036235.1" } ] } }, { "isoform_ac": "A0A8V0ZX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX49/entry", "sequence": { "sequence": "MSSHGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 499, "header": "tr|A0A8V0ZX49-1|A0A3Q2TVY9_CHICK Computationally mapped isoform of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "locus": { "chromosome": "11", "start_pos": 7329417, "end_pos": 7304449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059364.1", "url": "https://www.ensembl.org/id/ENSGALT00010059364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036238.1", "url": "https://www.ensembl.org/id/ENSGALP00010036238.1" } ] } }, { "isoform_ac": "A0A8V0ZX52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX52/entry", "sequence": { "sequence": "MSSHVLLVTILVVEGIAVAQKTQGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 503, "header": "tr|A0A8V0ZX52-1|A0A3Q2TVY9_CHICK Computationally mapped isoform of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "locus": { "chromosome": "11", "start_pos": 7329417, "end_pos": 7304449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059369.1", "url": "https://www.ensembl.org/id/ENSGALT00010059369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036243.1", "url": "https://www.ensembl.org/id/ENSGALP00010036243.1" } ] } }, { "isoform_ac": "A0A8V1A4L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4L5/entry", "sequence": { "sequence": "MLHVLLVTILVVEGIAVAQKTQGGQNIGLNRIPPTQCDNWVRTSNGGHFASPNYPNTYPPNQECIYILEAAPRQRIELTFDEPYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGLKSPALIRSTGRFMWIKFTSDEELEGKGFQAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPNAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVMLQTGTGVVRMWADEGSRLSRFRMLFTSFVDPPCSGNTYFCHSNMCINNSLVCNGIQNCAYPWDENHCREKKKSGLFEQITRTHGTIIGITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELENYQKMRRSSTASRCIHDHHCGSQASNIKQSRTNLSSMELPFHNDFAQPQPMKTFNSTFKKSSYTFKQAHDCPEQVIEDRVMEEIPCEIYVRGREDTAQGSLSIDF", "length": 517, "header": "tr|A0A8V1A4L5-1|A0A3Q2TVY9_CHICK Computationally mapped isoform of Neuropilin and tolloid like 2 OS=Gallus gallus OX=9031 GN=NETO2 PE=4 SV=1 CANONICAL=A0A3Q2TVY9-1" }, "locus": { "chromosome": "11", "start_pos": 7329417, "end_pos": 7305393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059356.1", "url": "https://www.ensembl.org/id/ENSGALT00010059356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036232.1", "url": "https://www.ensembl.org/id/ENSGALP00010036232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0098696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098696", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TVY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 520, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TVY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TVY9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVY9" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 154, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLR6-1", "uniprot_ac": "Q5ZLR6", "uniprot_id": "ARHG6_CHICK", "mass": { "chemical_mass": 85908.0, "monoisotopic_mass": 85908.0 }, "refseq": { "ac": "NP_001006432", "name": "rho guanine nucleotide exchange factor 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432" }, "gene_names": [ { "name": "ARHGEF6", "type": "recommended", "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ] }, { "name": "ARHGEF6", "type": "synonym", "evidence": [ { "id": "NP_001006432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432" } ] }, { "name": "RCJMB04_5b15", "type": "synonym", "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 6", "type": "recommended", "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6/entry#names_and_taxonomy" } ] }, { "name": "Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6", "type": "synonym", "evidence": [ { "id": "NP_001006432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432" } ] }, { "name": "Rac/Cdc42 guanine nucleotide exchange factor 6", "type": "synonym", "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 6", "type": "synonym", "evidence": [ { "id": "NP_001006432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719668.1, ERR2365565.59413.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Jan 13, 2005 this sequence version replaced XP_420235.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432" } ] }, { "annotation": "Acts as a RAC1 guanine nucleotide exchange factor (GEF).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6", "locus": { "chromosome": "4", "start_pos": 4329627, "end_pos": 4360781, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015866", "url": "https://www.ensembl.org/id/ENSGALG00010015866" } ] } } ], "crossref": [ { "id": "Q5ZLR6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422247", "url": "https://www.ncbi.nlm.nih.gov/gene/422247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q5ZLR6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q5ZLR6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422247", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YTK9", "url": "https://www.orthodb.org/?gene=A0A8V0YTK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVF4", "url": "https://www.orthodb.org/?gene=A0A8V0YVF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVF9", "url": "https://www.orthodb.org/?gene=A0A8V0YVF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0A9", "url": "https://www.orthodb.org/?gene=A0A8V0Z0A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLR6", "url": "https://www.orthodb.org/?gene=Q5ZLR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46026:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46026:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLR6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLR6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006432", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLR6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPEEQVVTWLISLGVLNSPKKIVDDPEEFLKTSLKDGTVLCKLIHRLLPGSAEKYCLEPKNEADCISNIQEFLRGCAVLKVELFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKERMSYILKDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 764, "header": "sp|Q5ZLR6-1|ARHG6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK9/entry", "sequence": { "sequence": "MNPEEQVVTWLISLGVLNSPKKIVDDPEEFLKTSLKDGTVLCKLIHRLLPGSAEKYCLEPKNEADCISNIQEFLRGCAVLKVEEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKEDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 695, "header": "tr|A0A8V0YTK9-1|ARHG6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "locus": { "chromosome": "4", "start_pos": 4360750, "end_pos": 4331575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038236.1", "url": "https://www.ensembl.org/id/ENSGALT00010038236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022069.1", "url": "https://www.ensembl.org/id/ENSGALP00010022069.1" } ] } }, { "isoform_ac": "A0A8V0YVF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF4/entry", "sequence": { "sequence": "MRADAAASPAALCSRLAGGDGAAGILHPPVAASGLFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKVLRRQSKAVEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKEDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 717, "header": "tr|A0A8V0YVF4-1|ARHG6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "locus": { "chromosome": "4", "start_pos": 4355373, "end_pos": 4331575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038222.1", "url": "https://www.ensembl.org/id/ENSGALT00010038222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022060.1", "url": "https://www.ensembl.org/id/ENSGALP00010022060.1" } ] } }, { "isoform_ac": "A0A8V0YVF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF9/entry", "sequence": { "sequence": "MSGTIWNRATQRHSTELCGCLQGSIPSLHCEALGTHSSGAAFGGPSTRCSECVSTPSCSDPCALLQHCSYKNAVNTIYAVWIFLSFSILSPLFFSVIFLGAFPSFLSFLLSPFLSPFSLSFLLSQFPSFPVSFPISIFFPLPPSPPLPPHRVLSLPSLPHLPFPSPLRLPPAAGSGAERGGGAACHFPFPFLPIPRSAIRLRVRAAAPGPAPQQHRCRHAPGLLARPSAALFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKVLRRQSKAVEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKEDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 913, "header": "tr|A0A8V0YVF9-1|ARHG6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "locus": { "chromosome": "4", "start_pos": 4357153, "end_pos": 4331575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038229.1", "url": "https://www.ensembl.org/id/ENSGALT00010038229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022065.1", "url": "https://www.ensembl.org/id/ENSGALP00010022065.1" } ] } }, { "isoform_ac": "A0A8V0Z0A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0A9/entry", "sequence": { "sequence": "MSGTIWNRATQRHSTELCGCLQGSIPSLHCEALGTHSSGAAFGGPSTRCSECVSTPSCSDPCALLQHCSYKNAVNTIYAVWIFLSFSILSPLFFSVIFLGAFPSFLSFLLSPFLSPFSLSFLLSQFPSFPVSFPISIFFPLPPSPPLPPHRVLSLPSLPHLPFPSPLRLPPAAGSGAERGGGAACHFPFPFLPIPRSAIRLRVRAAAPGPAPQQHRCRHAPGLLARPSAALFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKVLRRQSKAVEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKERMSYILKDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 920, "header": "tr|A0A8V0Z0A9-1|ARHG6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "locus": { "chromosome": "4", "start_pos": 4357153, "end_pos": 4331575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038226.1", "url": "https://www.ensembl.org/id/ENSGALT00010038226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022063.1", "url": "https://www.ensembl.org/id/ENSGALP00010022063.1" } ] } }, { "isoform_ac": "Q5ZLR6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6/entry#Q5ZLR6-1", "sequence": { "sequence": "MNPEEQVVTWLISLGVLNSPKKIVDDPEEFLKTSLKDGTVLCKLIHRLLPGSAEKYCLEPKNEADCISNIQEFLRGCAVLKVELFEPHDLYSGEQFSKVLSTLTAVNKATEDQPSEGPCSHPSALSSAAGGAHTDSNSTASQSAKEMTENGSHQLVVKARFNFKQTNEDELSVNKGDIIYVTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTDKPLSPKALKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYDKLSAVDIASLLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEKEERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTKLEDAEGNEHMFEIAGNMMERITVSCSTSQDLHEWLEHLQRLTKGTCNTVSKTQSWSAHSTFGSTGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKERMSYILKDSSKSPKTMKKFLPKRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGFQQALSSGSRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQENKRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA", "length": 764, "header": "sp|Q5ZLR6-1|ARHG6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1 CANONICAL=Q5ZLR6-1" }, "locus": { "chromosome": "4", "start_pos": 4360750, "end_pos": 4331575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038240.1", "url": "https://www.ensembl.org/id/ENSGALT00010038240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022072.1", "url": "https://www.ensembl.org/id/ENSGALP00010022072.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422247", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" }, { "id": "R-GGA-8964616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964616", "resource": "Reactome", "description": "G beta:gamma signalling through CDC42" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR6", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLR6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 764, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLR6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLR6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" }, { "id": "PRU00044", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00044" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000255", "start_pos": 1, "end_pos": 110, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" }, { "id": "PRU00062", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00062" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000255", "start_pos": 233, "end_pos": 413, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 435, "end_pos": 540, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZLR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR6" }, { "id": "PRU00192", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000255", "start_pos": 152, "end_pos": 211, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZHM5-1", "uniprot_ac": "Q5ZHM5", "uniprot_id": "RER1_CHICK", "mass": { "chemical_mass": 23032.0, "monoisotopic_mass": 23032.0 }, "refseq": { "ac": "NP_001006300", "name": "protein RER1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300" }, "gene_names": [ { "name": "RER1", "type": "recommended", "evidence": [ { "id": "Q5ZHM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ] }, { "name": "RCJMB04_35f13", "type": "synonym", "evidence": [ { "id": "Q5ZHM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ] }, { "name": "RER1", "type": "synonym", "evidence": [ { "id": "NP_001006300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300" } ] } ], "protein_names": [ { "name": "Protein RER1", "type": "recommended", "evidence": [ { "id": "Q5ZHM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5/entry#names_and_taxonomy" } ] }, { "name": "RER1 retention in endoplasmic reticulum 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300" } ] }, { "name": "protein RER1", "type": "synonym", "evidence": [ { "id": "NP_001006300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721109.1, CR390617.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Jan 13, 2005 this sequence version replaced XP_417559.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006300", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300" } ] }, { "annotation": "Involved in the retention or retrieval of proteins localized in the endoplasmic reticulum from the early Golgi compartment, including the gamma-secretase complex subunit (By similarity). In addition to its role in the control of protein trafficking, the RER1-dependent Golgi apparatus-endoplasmic reticulum retrieval system may regulate proteasomal degradation of alpha-synuclein (SNCA) (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5#function" }, { "database": "UniProtKB", "id": "Q9CQU3", "url": "https://www.uniprot.org/uniprotkb/Q9CQU3#function" }, { "database": "UniProtKB", "id": "O15258", "url": "https://www.uniprot.org/uniprotkb/O15258#function" } ] }, { "annotation": "Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K5#function" }, { "database": "UniProtKB", "id": "PIRNR016013", "url": "https://www.uniprot.org/uniprotkb/PIRNR016013#function" }, { "database": "UniProtKB", "id": "ARBA00003348", "url": "https://www.uniprot.org/uniprotkb/ARBA00003348#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RER1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5", "locus": { "chromosome": "21", "start_pos": 1548432, "end_pos": 1558404, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020027", "url": "https://www.ensembl.org/id/ENSGALG00010020027" } ] } } ], "crossref": [ { "id": "Q5ZHM5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZHM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021683", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021683", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419397", "url": "https://www.ncbi.nlm.nih.gov/gene/419397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419397", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWYVVCY", "url": "https://omabrowser.org/oma/group/GWYVVCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5K5", "url": "https://www.orthodb.org/?gene=A0A8V0Z5K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCA9", "url": "https://www.orthodb.org/?gene=A0A8V0ZCA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZHM5", "url": "https://www.orthodb.org/?gene=Q5ZHM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10743", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10743", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10743:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10743:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZHM5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZHM5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006300", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006300", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHM5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTRQNEEFRPFIRRLPEFKFWHSATKGILVAMACTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRKYKGKEDVGKTFAS", "length": 196, "header": "sp|Q5ZHM5-1|RER1_CHICK Isoform 1 of Protein RER1 OS=Gallus gallus OX=9031 GN=RER1 PE=2 SV=1 CANONICAL=Q5ZHM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K5/entry", "sequence": { "sequence": "MLPICCFVFTATMSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTRQNEEFRPFIRRLPEFKFWHSATKGILVAMACTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRKYKGKEDVGKTFAS", "length": 208, "header": "tr|A0A8V0Z5K5-1|RER1_CHICK Computationally mapped isoform of Protein RER1 OS=Gallus gallus OX=9031 GN=RER1 PE=2 SV=1 CANONICAL=Q5ZHM5-1" }, "locus": { "chromosome": "21", "start_pos": 1555633, "end_pos": 1552137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048377.1", "url": "https://www.ensembl.org/id/ENSGALT00010048377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028523.1", "url": "https://www.ensembl.org/id/ENSGALP00010028523.1" } ] } }, { "isoform_ac": "A0A8V0ZCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA9/entry", "sequence": { "sequence": "MLYCLVTPYLKILSSLEEKNIYLFWFCSLSLDTEVTGVWCCSAYQCLDVITQLLPYQATMSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTRQNEEFRPFIRRLPEFKFWHSATKGILVAMACTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRKYKGKEDVGKTFAS", "length": 255, "header": "tr|A0A8V0ZCA9-1|RER1_CHICK Computationally mapped isoform of Protein RER1 OS=Gallus gallus OX=9031 GN=RER1 PE=2 SV=1 CANONICAL=Q5ZHM5-1" }, "locus": { "chromosome": "21", "start_pos": 1556062, "end_pos": 1552137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048383.1", "url": "https://www.ensembl.org/id/ENSGALT00010048383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028527.1", "url": "https://www.ensembl.org/id/ENSGALP00010028527.1" } ] } }, { "isoform_ac": "A0A8V0ZCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV1/entry", "sequence": { "sequence": "MSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQMMVLPYPQGKMKNFGLSFGGSQSLNSGTRPLKASWLLWHVHSLRLSTFLFFGQSL", "length": 117, "header": "tr|A0A8V0ZCV1-1|RER1_CHICK Computationally mapped isoform of Protein RER1 OS=Gallus gallus OX=9031 GN=RER1 PE=2 SV=1 CANONICAL=Q5ZHM5-1" }, "locus": { "chromosome": "21", "start_pos": 1555597, "end_pos": 1553057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048373.1", "url": "https://www.ensembl.org/id/ENSGALT00010048373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028521.1", "url": "https://www.ensembl.org/id/ENSGALP00010028521.1" } ] } }, { "isoform_ac": "Q5ZHM5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5/entry#Q5ZHM5-1", "sequence": { "sequence": "MSEGDSIGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWIVTLGLSFIYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTRQNEEFRPFIRRLPEFKFWHSATKGILVAMACTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRKYKGKEDVGKTFAS", "length": 196, "header": "sp|Q5ZHM5-1|RER1_CHICK Isoform 1 of Protein RER1 OS=Gallus gallus OX=9031 GN=RER1 PE=2 SV=1 CANONICAL=Q5ZHM5-1" }, "locus": { "chromosome": "21", "start_pos": 1555597, "end_pos": 1552137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048385.1", "url": "https://www.ensembl.org/id/ENSGALT00010048385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028529.1", "url": "https://www.ensembl.org/id/ENSGALP00010028529.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419397", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419397", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140SRF8-1", "protein_name": "Protein RER1", "gene_name": "Rer1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMNEDSSAAGGGGVKKFFQRLSQTYQSALDRSTPHTRMRWVFAGFLLLLFVLRIFIYQGWYIVCYALGIYHLNLFIAFLTPKIDPEFDPYSQDDEDEGPNLPTRSNEEFRPFIRRLPEFKFWLSVAKSTLIGLICTFFDFFNVPVFWPILVMYFITLFCITMKRQIKHMIKYKYLPFTRNKPRYQRVNDLAGSGPGSVAGNSKXQLAAQTSDTRATAAGSGDPSNASSAAAAPPSPTSDSAATKDVGSPTASSIKPPQIIAIEDY", "length": 265 }, "evidence": [ { "id": "Q5ZHM5", "url": "https://omabrowser.org/oma/group/Q5ZHM5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O15258-1", "protein_name": "Protein RER1", "gene_name": "RER1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEGDSVGESVHGKPSVVYRFFTRLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWHAATKGILVAMVCTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRRYRGKEDAGKAFAS", "length": 196 }, "evidence": [ { "id": "Q5ZHM5", "url": "https://omabrowser.org/oma/group/Q5ZHM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25560-1", "protein_name": "Protein RER1", "gene_name": "RER1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDYDSSDTMNGGSSNPLITKMNTMKLLYQHYLDKVTPHAKERWAVLGGLLCLFMVRITMAEGWYVICYGLGLFLLNQFLAFLTPKFDMSLQQDEENNELEAGEKSEEFRPFIRRLPEFKFWYNSIRATVISLLLSLFSIFDIPVFWPILLMYFILLFFLTMRRQIQHMIKYRYIPLDIGKKKYSHSSN", "length": 188 }, "evidence": [ { "id": "Q5ZHM5", "url": "https://omabrowser.org/oma/group/Q5ZHM5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q498C8-1", "protein_name": "Protein RER1", "gene_name": "Rer1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEGDSVGDSVHGKPSVVYRFFSRLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWHAATKGILVAMICTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRRYKGKEDVGKTFAS", "length": 196 }, "evidence": [ { "id": "Q5ZHM5", "url": "https://omabrowser.org/oma/group/Q5ZHM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CQU3-1", "protein_name": "Protein RER1", "gene_name": "Rer1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEGDSVGDSVHGKPSVVYRFFSRLGQIYQSWLDKSTPYTAVRWVVTLGLSFVYMIRVYLLQGWYIVTYALGIYHLNLFIAFLSPKVDPSLMEDSDDGPSLPTKQNEEFRPFIRRLPEFKFWHAATKGILVAMICTFFEAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYIPFTHGKRRYKGKEDVGKTFAS", "length": 196 }, "evidence": [ { "id": "Q5ZHM5", "url": "https://omabrowser.org/oma/group/Q5ZHM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "protein retention in ER lumen", "id": "GO:0006621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006621", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" }, { "name": "maintenance of protein localization in endoplasmic reticulum", "id": "GO:0035437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035437", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetylcholine receptor binding", "id": "GO:0033130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033130", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZHM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZHM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 196, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZHM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZHM5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZI58-1", "uniprot_ac": "Q5ZI58", "uniprot_id": "ATOSA_CHICK", "mass": { "chemical_mass": 122472.0, "monoisotopic_mass": 122472.0 }, "refseq": {}, "gene_names": [ { "name": "ATOSA", "type": "recommended", "evidence": [ { "id": "Q5ZI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ] }, { "name": "FAM214A", "type": "recommended", "evidence": [ { "id": "Q5ZI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ] }, { "name": "FAM214A", "type": "synonym", "evidence": [ { "id": "Q5ZI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ] }, { "name": "RCJMB04_30b20", "type": "synonym", "evidence": [ { "id": "Q5ZI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ] } ], "protein_names": [ { "name": "Atos homolog protein A", "type": "recommended", "evidence": [ { "id": "Q5ZI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB8#function" }, { "database": "UniProtKB", "id": "ARBA00037191", "url": "https://www.uniprot.org/uniprotkb/ARBA00037191#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN7#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG1#function" }, { "database": "UniProtKB", "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58#function" }, { "database": "UniProtKB", "id": "Q69ZK7", "url": "https://www.uniprot.org/uniprotkb/Q69ZK7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATOSA", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58", "locus": {} } ], "crossref": [ { "id": "Q5ZI58", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042839", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042839", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415416", "url": "https://www.ncbi.nlm.nih.gov/gene/415416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415416", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTHPRSQ", "url": "https://omabrowser.org/oma/group/QTHPRSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8I3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI58", "url": "https://www.orthodb.org/?gene=Q5ZI58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI58", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI58", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI58-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAERNGSSTDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1093, "header": "sp|Q5ZI58-1|ATOSA_CHICK Isoform 1 of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=2 CANONICAL=Q5ZI58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I3/entry", "sequence": { "sequence": "MGVTPAQRDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1091, "header": "tr|A0A8V0Z8I3-1|ATOSA_CHICK Computationally mapped isoform of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=1 CANONICAL=Q5ZI58-1" }, "locus": { "chromosome": "10", "start_pos": 8748109, "end_pos": 8724351, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050042.1", "url": "https://www.ensembl.org/id/ENSGALT00010050042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029564.1", "url": "https://www.ensembl.org/id/ENSGALP00010029564.1" } ] } }, { "isoform_ac": "A0A8V0ZEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB8/entry", "sequence": { "sequence": "MDRAPRGPDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1091, "header": "tr|A0A8V0ZEB8-1|ATOSA_CHICK Computationally mapped isoform of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=1 CANONICAL=Q5ZI58-1" }, "locus": { "chromosome": "10", "start_pos": 8748109, "end_pos": 8715587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050044.1", "url": "https://www.ensembl.org/id/ENSGALT00010050044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029566.1", "url": "https://www.ensembl.org/id/ENSGALP00010029566.1" } ] } }, { "isoform_ac": "A0A8V0ZFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG1/entry", "sequence": { "sequence": "MIKTSFRNKENLSEVRPLCACDMSSVSRSAPVKLGIFFPLRLVEPAMDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1130, "header": "tr|A0A8V0ZFG1-1|ATOSA_CHICK Computationally mapped isoform of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=1 CANONICAL=Q5ZI58-1" }, "locus": { "chromosome": "10", "start_pos": 8748109, "end_pos": 8711972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050047.1", "url": "https://www.ensembl.org/id/ENSGALT00010050047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029569.1", "url": "https://www.ensembl.org/id/ENSGALP00010029569.1" } ] } }, { "isoform_ac": "A0A8V0ZFN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN7/entry", "sequence": { "sequence": "MKAEKQSNTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPKTKGNVFIFYIYSLLFNSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1081, "header": "tr|A0A8V0ZFN7-1|ATOSA_CHICK Computationally mapped isoform of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=1 CANONICAL=Q5ZI58-1" }, "locus": { "chromosome": "10", "start_pos": 8748109, "end_pos": 8730012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050040.1", "url": "https://www.ensembl.org/id/ENSGALT00010050040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029562.1", "url": "https://www.ensembl.org/id/ENSGALP00010029562.1" } ] } }, { "isoform_ac": "Q5ZI58-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58/entry#Q5ZI58-1", "sequence": { "sequence": "MNAERNGSSTDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1093, "header": "sp|Q5ZI58-1|ATOSA_CHICK Isoform 1 of Atos homolog protein A OS=Gallus gallus OX=9031 GN=ATOSA PE=2 SV=2 CANONICAL=Q5ZI58-1" }, "locus": { "chromosome": "10", "start_pos": 8748109, "end_pos": 8717347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050046.1", "url": "https://www.ensembl.org/id/ENSGALT00010050046.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029568.1", "url": "https://www.ensembl.org/id/ENSGALP00010029568.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:415416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415416", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MUG2-1", "protein_name": "Atos homolog protein A", "gene_name": "Fam214a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKPDRDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGTARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGTDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNILYEKRIQEQELKAYQHRGPGEIEHRCPSSSQSLCNKHTWTMAPVSALHVRSGMTPEFTAAIRNVRLCPGTGSKSDHGASQASVLGFSGTMGEVRSQEASVRTLKSLSVIDSSVSSCQSSRQAVGEPNPLMDSLIQDRQEVIARIAQHLIHCDPSSSRMSEHPFSTQESTSLGSKLHRVPQEIEGVRRCKEAFSVSFGSPEIRSSDDTSEGKGRGKSETTQGETCTSHSPYPRQPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTAHIPRPAFSKHDSNSIPSKVFRSSYDDKTLLKVNRDNASLSAAHTEVSLLGDRGDGKSPQPSKCFRSFKYSPQEKSLKHEVRTQHQEHPDDIIHSTGQDAHKAAGLLTSSNMTLCNESNLDLISRLESTPCKSQHKEQEMSREIEKQCSHCNSIDKQFCTNKCTEKIKDENYNPGSPSQLQCDDSKGIDSKLKVTVSEMSDCFNKYKTNCSIKDSKRSKTCEQSSQLSTENDLSEDTEGFRCTASNQLKTEQEEKEDSAAGKPQRKSVKHCLSTSERLKSADVLRDTLKHSSVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDTSLLHLRSLSSRSSRPCLNIEEDPDAHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVMYDLRGMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1076 }, "evidence": [ { "id": "Q5ZI58", "url": "https://omabrowser.org/oma/group/Q5ZI58/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZMC3-1", "protein_name": "Atos homolog protein A", "gene_name": "Atosa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVFSGNKGLRRQDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGAARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGTDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWSFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNIGLYEKRIQEQELRACQHRGPGEVEYRCPSSSQSLCSKHTWTMAPVSALHVRSGMPPEYTAAIRNVRLCPGTGSKSDNGTPQASVLGFSGTGEVRSQEASVRTFKSLSVIDSSVSSCQSSRQPVGEPNPLIDSLIQDRQEVIARIAQHLIHCDPSSSRMSELPFNTPESTSLSPKLHPVSQESGYSRRCKEAFSVSFGSPEFGSPGDSKEGKVKEKLETRQGETCASHSPYPRQPAGEANPLIGSLLLERQDVIARIAQHLEHIDPTAHIPRPAFSKHDSNSIPSKVFRSSFHDKTMLKKDRENVSVSATHTEVSLLGDRGDGKSPKPSKCFRSFKNSPQEKSLKPEESAQHQNHPDDITHTARQELLNKAAGLLTSSNSSLCNESSLALIGRLESTSCKLQLRKQEMSHETEKQCLHCNSIDKQICTNKCTEKIKDENSPGSLSHLQCDESRGIDPKIKVTMLEMPDYLNKYKTNCSNKDSKRSKTCEQNIQLGTENYLSEDTEGSKSTISDQLKTEQEENKDSVAGKPPSVKHCLSTSERLKNADMLDFSSQRTTLKHSSVWRKHDFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDTSLLHLRSLSSKSSRPCLNIEADPGVHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVVYDLRSMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1086 }, "evidence": [ { "id": "Q5ZI58", "url": "https://omabrowser.org/oma/group/Q5ZI58/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32MH5-1", "protein_name": "Atos homolog protein A", "gene_name": "ATOSA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTAAVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETNPLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSVSISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICTNKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQLNSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGFTAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1076 }, "evidence": [ { "id": "Q5ZI58", "url": "https://omabrowser.org/oma/group/Q5ZI58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q69ZK7-1", "protein_name": "Atos homolog protein A", "gene_name": "Atosa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPDRDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGTARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGADLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWSFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNIGLYEKRIQEQELRACQHHGPGEVEYRCPSSSQSLCSKHTWTMAPVSALHVRSGMPPEYTAAIRNVRLCPGTGSKSDQGAPQASVLGFSGTGGEVRSQEASVRTFKSLPVVDSSVSSCQSSRQPVGEPNPLMDSLIQDRQEVIARIAQHLIHCDPSSSRMSELPFNTQESTSLSPKLHPVSQESGCVRRYKEAFSVSFGSPEFGSPGDSREGKVREKSETRPGETCTSHSLYPRQPAGEANPLIGSLLQERQDVIARIAQHLEHIDPAAHIPRPAFSKHDSNSIPSKVFRSSFDDKTLLKKGRENVSVSVSHTEVSLLGDRGDGESLKPSKCLRSFKYSPQEKPLKPEVRTQHQNHPDSITPTARQELLNKAAGLLTSSNTALCKESSLGLVSRLESTSCKLQLKEQEMSHETEKQCLHCNSIDKQICTNTCTEKINDEHSPGSLRHLQCDDSKGIDSKLKVTLLEMPDSLNKNKTNCSSKDSKRSKTCEQSIRVGTENDLSEENEGPGSTVSDRLKTEQEAKRDSGAGKPHSVKHCLSAGERLHSADMLRTTLKHSSVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDASLLHLRSLSSKSSRPCLNIDEDPDVHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVVYDLRGMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1075 }, "evidence": [ { "id": "Q5ZI58", "url": "https://omabrowser.org/oma/group/Q5ZI58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI58", "url": "https://www.uniprot.org/uniprotkb/Q5ZI58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI58-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1093, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI58-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI58" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 608, "end_pos": 610 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 982, "end_pos": 984 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZKB6-1", "uniprot_ac": "Q5ZKB6", "uniprot_id": "CRIPT_CHICK", "mass": { "chemical_mass": 11256.0, "monoisotopic_mass": 11256.0 }, "refseq": { "ac": "NP_001026225", "name": "cysteine-rich PDZ-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" }, "gene_names": [ { "name": "CRIPT", "type": "recommended", "evidence": [ { "id": "Q5ZKB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ] }, { "name": "CRIPT", "type": "synonym", "evidence": [ { "id": "NP_001026225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] }, { "name": "RCJMB04_11o12", "type": "synonym", "evidence": [ { "id": "Q5ZKB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ] } ], "protein_names": [ { "name": "Cysteine-rich PDZ-binding protein", "type": "recommended", "evidence": [ { "id": "Q5ZKB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6/entry#names_and_taxonomy" } ] }, { "name": "Cysteine-rich interactor of PDZ three", "type": "synonym", "evidence": [ { "id": "Q5ZKB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6/entry#names_and_taxonomy" } ] }, { "name": "Cysteine-rich interactor of PDZ3", "type": "synonym", "evidence": [ { "id": "Q5ZKB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6/entry#names_and_taxonomy" } ] }, { "name": "cysteine-rich PDZ-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001026225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] }, { "name": "cysteine-rich interactor of PDZ three", "type": "synonym", "evidence": [ { "id": "NP_001026225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] }, { "name": "cysteine-rich interactor of PDZ3", "type": "synonym", "evidence": [ { "id": "NP_001026225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] }, { "name": "postsynaptic protein CRIPT", "type": "synonym", "evidence": [ { "id": "NP_001026225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720168.1, HAEK01023852.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000063.1. On Aug 8, 2005 this sequence version replaced XP_419466.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026225", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225" } ] }, { "annotation": "As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6#function" }, { "database": "UniProtKB", "id": "Q9P021", "url": "https://www.uniprot.org/uniprotkb/Q9P021#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRIPT", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6", "locus": { "chromosome": "3", "start_pos": 26452504, "end_pos": 26446637, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018441", "url": "https://www.ensembl.org/id/ENSGALG00010018441" } ] } } ], "crossref": [ { "id": "Q5ZKB6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010014", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421412", "url": "https://www.ncbi.nlm.nih.gov/gene/421412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421412", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPCDKCE", "url": "https://omabrowser.org/oma/group/MPCDKCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDD0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKB6", "url": "https://www.orthodb.org/?gene=Q5ZKB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11805:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11805:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKB6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKB6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026225", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKB6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCEKCERKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKGICSMCGKKVLDTKNYKQTSV", "length": 101, "header": "sp|Q5ZKB6-1|CRIPT_CHICK Isoform 1 of Cysteine-rich PDZ-binding protein OS=Gallus gallus OX=9031 GN=CRIPT PE=3 SV=1 CANONICAL=Q5ZKB6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC5/entry", "sequence": { "sequence": "MVCEKCERKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKDASYWAEYLAPFCFRKRD", "length": 98, "header": "tr|A0A8V0ZDC5-1|A0A8V0ZDC5_CHICK Computationally mapped isoform of Cysteine-rich PDZ-binding protein OS=Gallus gallus OX=9031 GN=CRIPT PE=3 SV=1 CANONICAL=Q5ZKB6-1" }, "locus": { "chromosome": "3", "start_pos": 26449627, "end_pos": 26446981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044568.1", "url": "https://www.ensembl.org/id/ENSGALT00010044568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026527.1", "url": "https://www.ensembl.org/id/ENSGALP00010026527.1" } ] } }, { "isoform_ac": "A0A8V0ZDD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDD0/entry", "sequence": { "sequence": "ERSGGEKAFSWQNNDPRALTPSRAGLAPRGGLTTRRAHLALTRDAGRPATGWRQLRGGPGSGGCFAGPPWCARSRKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKGICSMCGKKVLDTKNYKQTSV", "length": 168, "header": "tr|A0A8V0ZDD0-1|CRIPT_CHICK Computationally mapped isoform of Cysteine-rich PDZ-binding protein OS=Gallus gallus OX=9031 GN=CRIPT PE=3 SV=1 CANONICAL=Q5ZKB6-1" }, "locus": { "chromosome": "3", "start_pos": 26450337, "end_pos": 26446775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044576.1", "url": "https://www.ensembl.org/id/ENSGALT00010044576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026533.1", "url": "https://www.ensembl.org/id/ENSGALP00010026533.1" } ] } }, { "isoform_ac": "Q5ZKB6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6/entry#Q5ZKB6-1", "sequence": { "sequence": "MVCEKCERKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFAICRICKSSVHQPGSHYCQGCAYKKGICSMCGKKVLDTKNYKQTSV", "length": 101, "header": "sp|Q5ZKB6-1|CRIPT_CHICK Isoform 1 of Cysteine-rich PDZ-binding protein OS=Gallus gallus OX=9031 GN=CRIPT PE=3 SV=1 CANONICAL=Q5ZKB6-1" }, "locus": { "chromosome": "3", "start_pos": 26450337, "end_pos": 26446981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044573.1", "url": "https://www.ensembl.org/id/ENSGALT00010044573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026530.1", "url": "https://www.ensembl.org/id/ENSGALP00010026530.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421412", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I8N1-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "Cript", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVCEKCEKKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70333-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "Cript", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZC66-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "CRIPT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVCEKCEKKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q567Z6-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "cript", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKMLTSKKARFDPYGKSGFATCRICKSSVHQSGSHYCQGCAYKKGICAMCGKKVIDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q792Q4-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "Cript", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCEKCEKKLGRVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P021-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "CRIPT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCEKCEKKLGTVITPDTWKDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICAMCGKKVLDTKNYKQTSV", "length": 101 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SYB4-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCDKCEKKLSKVIVPDKWKDGARNVTEGGGRKINENKLLSKKNRWSPYSTCTTKCMICKQQVHQDGKYCHTCAYSKGVCAMCGKQVLDTKMYKQSNV", "length": 98 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VL77-1", "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "Dmel\\CG4537", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVCEKCEAKLSKVSAPNPWRTSTAPAGGRKINENKALSSARERYNPIGTALPPCRICRQKVHQMGSHYCQACAYKKAICAMCGKKIMNTKNYKQSST", "length": 97 }, "evidence": [ { "id": "Q5ZKB6", "url": "https://omabrowser.org/oma/group/Q5ZKB6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKB6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 101, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKB6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKB6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZIF1-1", "uniprot_ac": "Q5ZIF1", "uniprot_id": "APMAP_CHICK", "mass": { "chemical_mass": 46115.0, "monoisotopic_mass": 46115.0 }, "refseq": { "ac": "NP_001006177", "name": "adipocyte plasma membrane-associated protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" }, "gene_names": [ { "name": "APMAP", "type": "recommended", "evidence": [ { "id": "Q5ZIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ] }, { "name": "APMAP", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] }, { "name": "BSCv", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] }, { "name": "C20orf3", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] }, { "name": "C3H20ORF3", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] }, { "name": "RCJMB04_27f14", "type": "synonym", "evidence": [ { "id": "Q5ZIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ] } ], "protein_names": [ { "name": "Adipocyte plasma membrane-associated protein", "type": "recommended", "evidence": [ { "id": "Q5ZIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1/entry#names_and_taxonomy" } ] }, { "name": "adipocyte plasma membrane-associated protein", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] }, { "name": "protein BSCv", "type": "synonym", "evidence": [ { "id": "NP_001006177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR389678.1, AJ720833.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000062.1. On Jan 13, 2005 this sequence version replaced XP_415012.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APMAP", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1", "locus": { "chromosome": "3", "start_pos": 15521269, "end_pos": 15536405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018892", "url": "https://www.ensembl.org/id/ENSGALG00010018892" } ] } } ], "crossref": [ { "id": "Q5ZIF1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008651", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416715", "url": "https://www.ncbi.nlm.nih.gov/gene/416715", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416715", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416715", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCRTRAQ", "url": "https://omabrowser.org/oma/group/CCRTRAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF82", "url": "https://www.orthodb.org/?gene=A0A8V0ZF82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIF1", "url": "https://www.orthodb.org/?gene=Q5ZIF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10426:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10426:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIF1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIF1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIF1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEAEGLRQRRPLRPQVITEDSPAQEAKEGSAYSSKVFRVTFLTLAASLAVPLLGATVLLDCPIDPQPISLKEPPLLTGVLEPNNKLQKAERLWENQLVGPESIVNIGDVLFTGTADGKILKIEDGEVQTVARIGHGPCGTPEDEPTCGRPLGIRVGPNNTLFVADAYYGLYEVNPGTGETKMLVSTKTLIEGQKLSFLNDLTVTQDGRKIYFTDSSSKWQRRDFLFLVMEGTDDGRLLEYDTVTKEVKVLMVGLRFPNGVQLSPAEDFVLVLETAMARIRRYYVSGLMKGGADMFVENMPGLPDNIRLSSSGGYWVAMPVVRPNPGFSMLDFLSEKPWIKRMIFKLLSQETVTKLLPKRSLVVELSETGSYRRSFHDPTGLTVPYVSEAHEHNGYLYLGSFRSPFICRLNLQHV", "length": 415, "header": "sp|Q5ZIF1-1|APMAP_CHICK Isoform 1 of Adipocyte plasma membrane-associated protein OS=Gallus gallus OX=9031 GN=APMAP PE=2 SV=1 CANONICAL=Q5ZIF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF82/entry", "sequence": { "sequence": "MNEAEGLRQRRPLRPQVITEDSPAQEAKEGSAYSSKVFRVTFLTLAASLAVPLLGATVLLDCPIDPQPISLKEPPLLTGVLEPNNKLQKAERLWENQLVGPESIVNIGDVLFTGTADGKILKIEDGEVQTVARIGHGPCGTPEDEPTCGRPLGIRVGPNNTLFVADAYYGLYEVNPGTGETKMLVSTKTLIEGQKLSFLNDLTVTQDGRKIYFTDSSSKWQRRDFLFLVMEGTDDGRLLEYDTVTKEVKVLMVGLRFPNGVQLSPAEDFVLVLETAMARIRRYYVSGLMKGGADMFVENMPGLPDNIRLSSSGGYWVAMPVVRPNPGFSMLDFLSEKPWIKRMIFKKKERGVISALAMQQNRICIWMYEGRFHLHT", "length": 376, "header": "tr|A0A8V0ZF82-1|APMAP_CHICK Computationally mapped isoform of Adipocyte plasma membrane-associated protein OS=Gallus gallus OX=9031 GN=APMAP PE=2 SV=1 CANONICAL=Q5ZIF1-1" }, "locus": { "chromosome": "3", "start_pos": 15536359, "end_pos": 15524883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045669.1", "url": "https://www.ensembl.org/id/ENSGALT00010045669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027229.1", "url": "https://www.ensembl.org/id/ENSGALP00010027229.1" } ] } }, { "isoform_ac": "Q5ZIF1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1/entry#Q5ZIF1-1", "sequence": { "sequence": "MNEAEGLRQRRPLRPQVITEDSPAQEAKEGSAYSSKVFRVTFLTLAASLAVPLLGATVLLDCPIDPQPISLKEPPLLTGVLEPNNKLQKAERLWENQLVGPESIVNIGDVLFTGTADGKILKIEDGEVQTVARIGHGPCGTPEDEPTCGRPLGIRVGPNNTLFVADAYYGLYEVNPGTGETKMLVSTKTLIEGQKLSFLNDLTVTQDGRKIYFTDSSSKWQRRDFLFLVMEGTDDGRLLEYDTVTKEVKVLMVGLRFPNGVQLSPAEDFVLVLETAMARIRRYYVSGLMKGGADMFVENMPGLPDNIRLSSSGGYWVAMPVVRPNPGFSMLDFLSEKPWIKRMIFKLLSQETVTKLLPKRSLVVELSETGSYRRSFHDPTGLTVPYVSEAHEHNGYLYLGSFRSPFICRLNLQHV", "length": 415, "header": "sp|Q5ZIF1-1|APMAP_CHICK Isoform 1 of Adipocyte plasma membrane-associated protein OS=Gallus gallus OX=9031 GN=APMAP PE=2 SV=1 CANONICAL=Q5ZIF1-1" }, "locus": { "chromosome": "3", "start_pos": 15536359, "end_pos": 15524000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045675.1", "url": "https://www.ensembl.org/id/ENSGALT00010045675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027233.1", "url": "https://www.ensembl.org/id/ENSGALP00010027233.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 159, "start_aa": "Asn", "end_pos": 159, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn159", "evidence": [ { "id": "Q5ZIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416715", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416715", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9HDC9-1", "protein_name": "Adipocyte plasma membrane-associated protein", "gene_name": "APMAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNGTLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFSQETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV", "length": 416 }, "evidence": [ { "id": "Q5ZIF1", "url": "https://omabrowser.org/oma/group/Q5ZIF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M1B4-1", "protein_name": "Protein STRICTOSIDINE SYNTHASE-LIKE 13", "gene_name": "SSL13", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKKGQHGTYESMMTHHPILCIIALSVLFIAIDPFHMSPIGGREFKPVKHEVAPYKEVMGSWPRDNLSRLGNHGKLEFVDQVFGPESLEFDSLGRGPYTGLADGRVVRWMGEAIGWETFSVVTSKWSEEACVRGVDSTTNKQWKHEKLCGRPLGLRFHKETGNLYIADAYYGLLVVGPEGGIATPLATHVEGKPILFANDLDIHRNGSIFFTDTSKRYDRANHFFILLEGESTGRLLRYDPPTKTTHIVLEGLAFPNGIQLSKDQSFLLFTETTNCRLVKYWLEGPKMGEVEVVADLPGFPDNVRINEEGQFWVAIDCCRTPAQEVLTNNPWIRSIYFRLPIPMKLLAKTMGMRMYTVISRFDEEGKVLEVLEDRQGKVMKLWIGTVAHNHIATLPYPLTMNQ", "length": 403 }, "evidence": [ { "id": "Q5ZIF1", "url": "https://omabrowser.org/oma/group/Q5ZIF1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "arylesterase activity", "id": "GO:0004064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004064", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIF1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 415, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIF1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIF1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 159 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TW69-1", "uniprot_ac": "A0A3Q2TW69", "uniprot_id": "A0A3Q2TW69_CHICK", "mass": { "chemical_mass": 27715.0, "monoisotopic_mass": 27715.0 }, "refseq": { "ac": "XP_015131967", "name": "transmembrane protein 150C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131967" }, "gene_names": [ { "name": "TMEM150C", "type": "recommended", "evidence": [ { "id": "A0A3Q2TW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ] }, { "name": "TMEM150C", "type": "synonym", "evidence": [ { "id": "XP_015131967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131967" } ] } ], "protein_names": [ { "name": "Transmembrane protein 150C", "type": "synonym", "evidence": [ { "id": "A0A3Q2TW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 150C", "type": "synonym", "evidence": [ { "id": "XP_015131967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131967" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131967" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM150C", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69", "locus": { "chromosome": "4", "start_pos": 45977333, "end_pos": 45958833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003981", "url": "https://www.ensembl.org/id/ENSGALG00010003981" } ] } } ], "crossref": [ { "id": "A0A3Q2TW69", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TW69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011175", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422599", "url": "https://www.ncbi.nlm.nih.gov/gene/422599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422599", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYFIAVY", "url": "https://omabrowser.org/oma/group/VYFIAVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW69", "url": "https://www.orthodb.org/?gene=A0A3Q2TW69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBE0", "url": "https://www.orthodb.org/?gene=A0A8V0XBE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XI73", "url": "https://www.orthodb.org/?gene=A0A8V0XI73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XKX9", "url": "https://www.orthodb.org/?gene=A0A8V0XKX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMJ4", "url": "https://www.orthodb.org/?gene=A0A8V0XMJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015131967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDNKIIALNVPERKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249, "header": "tr|A0A3Q2TW69-1|A0A3Q2TW69_CHICK Isoform 1 of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TW69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69/entry", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDNKIIALNVPERKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249, "header": "tr|A0A3Q2TW69-1|A0A3Q2TW69_CHICK Isoform 1 of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "locus": { "chromosome": "4", "start_pos": 45975321, "end_pos": 45968176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009216.1", "url": "https://www.ensembl.org/id/ENSGALT00010009216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005444.1", "url": "https://www.ensembl.org/id/ENSGALP00010005444.1" } ] } }, { "isoform_ac": "A0A8V0XBE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBE0/entry", "sequence": { "sequence": "MPHCIPSSFGWRQARSDGGGLPSVAGFSFPAGTSGPRRSLPGTSAQGSLQPRPLKPKVWTGRNAACGCFCPLCLPYLRQLGYGLYFIAVEDNKIIALNVPERKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 306, "header": "tr|A0A8V0XBE0-1|A0A3Q2TW69_CHICK Computationally mapped isoform of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "locus": { "chromosome": "4", "start_pos": 45975321, "end_pos": 45963823, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009215.1", "url": "https://www.ensembl.org/id/ENSGALT00010009215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005443.1", "url": "https://www.ensembl.org/id/ENSGALP00010005443.1" } ] } }, { "isoform_ac": "A0A8V0XI73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI73/entry", "sequence": { "sequence": "MQRVDVFAPCVYPIYVSWVMDCVLYSSGRQQNYCTKCTGEFLNLNSSALVSCRKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 257, "header": "tr|A0A8V0XI73-1|A0A3Q2TW69_CHICK Computationally mapped isoform of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "locus": { "chromosome": "4", "start_pos": 45975321, "end_pos": 45968190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009212.1", "url": "https://www.ensembl.org/id/ENSGALT00010009212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005440.1", "url": "https://www.ensembl.org/id/ENSGALP00010005440.1" } ] } }, { "isoform_ac": "A0A8V0XKX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKX9/entry", "sequence": { "sequence": "MGAGRVLCGGEERTCASISLCSADCAGMDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDNKIIALNVPERKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 276, "header": "tr|A0A8V0XKX9-1|A0A3Q2TW69_CHICK Computationally mapped isoform of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "locus": { "chromosome": "4", "start_pos": 45975321, "end_pos": 45967685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009208.1", "url": "https://www.ensembl.org/id/ENSGALT00010009208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005436.1", "url": "https://www.ensembl.org/id/ENSGALP00010005436.1" } ] } }, { "isoform_ac": "A0A8V0XMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMJ4/entry", "sequence": { "sequence": "MLYLGGGSRAGMDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDNKIIALNVPERKPGSKRPPYISIAGDAPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNVSGLVALCLASFGMTLLGNFQLSNDEEIHNVGTSLTFGFGTLACWIQSALTLKINLKNEGRKAGIPRVALSAGITLCVVLYFILMAQGIHMYAARIQWGLVMCFLCYFGTFAVEFRHYRFEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 260, "header": "tr|A0A8V0XMJ4-1|A0A3Q2TW69_CHICK Computationally mapped isoform of Transmembrane protein 150C OS=Gallus gallus OX=9031 GN=TMEM150C PE=3 SV=1 CANONICAL=A0A3Q2TW69-1" }, "locus": { "chromosome": "4", "start_pos": 45975321, "end_pos": 45966225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009211.1", "url": "https://www.ensembl.org/id/ENSGALT00010009211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005439.1", "url": "https://www.ensembl.org/id/ENSGALP00010005439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422599", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422599", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A5D7C9-1", "protein_name": "Transmembrane protein 150C", "gene_name": "TMEM150C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTVFTSAGLWIVYFIAVEDDKIFPLNSAERKPGVKHAPYISIAGDEPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRKVGIPRVILSASITLCVVLYFILMAQGIHMYAARVQWGLVMCFLSYFGTFAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249 }, "evidence": [ { "id": "A0A3Q2TW69", "url": "https://omabrowser.org/oma/group/A0A3Q2TW69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DFH9-1", "protein_name": "Transmembrane protein 150C", "gene_name": "Tmem150c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGVKHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRAGIPRVILSAVITLCVVLYFILMAQDIHMYAARVQWGLVMCFLAYFGTLAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249 }, "evidence": [ { "id": "A0A3Q2TW69", "url": "https://omabrowser.org/oma/group/A0A3Q2TW69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B9EJG8-1", "protein_name": "Transmembrane protein 150C", "gene_name": "TMEM150C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAERKPGVKHAPYISIAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRVGIPRVILSASITLCVVLYFILMAQSIHMYAARVQWGLVMCFLSYFGTFAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249 }, "evidence": [ { "id": "A0A3Q2TW69", "url": "https://omabrowser.org/oma/group/A0A3Q2TW69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3I786-1", "protein_name": "Transmembrane protein 150C isoform X2", "gene_name": "Tmem150c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGAKHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRVGIPRVILSAVITLCVVLYFILMAQDIHMYAARVQWGLVMCFLSYFGTLAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249 }, "evidence": [ { "id": "A0A3Q2TW69", "url": "https://omabrowser.org/oma/group/A0A3Q2TW69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8C8S3-1", "protein_name": "Transmembrane protein 150C", "gene_name": "Tmem150c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGAKHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLAALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRAGIPRVILSAVITLCVVLYFILMAQDIHMYAARVQWGLVMCFLAYFGTLAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV", "length": 249 }, "evidence": [ { "id": "A0A3Q2TW69", "url": "https://omabrowser.org/oma/group/A0A3Q2TW69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "pmid": "" }, { "name": "proprioception", "id": "GO:0019230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019230", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mechanosensitive monoatomic cation channel activity", "id": "GO:0140135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140135", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW69" }, { "id": "PF10277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWH43-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 217, "start_aa": "Trp", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U7F8-1", "uniprot_ac": "A0A3Q2U7F8", "uniprot_id": "A0A3Q2U7F8_CHICK", "mass": { "chemical_mass": 55321.0, "monoisotopic_mass": 55321.0 }, "refseq": { "ac": "XP_004941151", "name": "ras-GEF domain-containing family member 1B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941151" }, "gene_names": [ { "name": "RASGEF1B", "type": "recommended", "evidence": [ { "id": "A0A3Q2U7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ] }, { "name": "RASGEF1B", "type": "synonym", "evidence": [ { "id": "XP_004941151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941151" } ] } ], "protein_names": [ { "name": "RasGEF domain family member 1B", "type": "synonym", "evidence": [ { "id": "A0A3Q2U7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8/entry#names_and_taxonomy" } ] }, { "name": "ras-GEF domain-containing family member 1B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004941151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941151" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004941151.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941151" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASGEF1B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8", "locus": { "chromosome": "4", "start_pos": 45182305, "end_pos": 45072034, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002880", "url": "https://www.ensembl.org/id/ENSGALG00010002880" } ] } } ], "crossref": [ { "id": "A0A3Q2U7F8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U7F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010903", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010903", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859744", "url": "https://www.ncbi.nlm.nih.gov/gene/100859744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859744", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U7F8", "url": "https://www.orthodb.org/?gene=A0A3Q2U7F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBN7", "url": "https://www.orthodb.org/?gene=A0A8V0XBN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBP2", "url": "https://www.orthodb.org/?gene=A0A8V0XBP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEL8", "url": "https://www.orthodb.org/?gene=A0A8V0XEL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEM3", "url": "https://www.orthodb.org/?gene=A0A8V0XEM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHC0", "url": "https://www.orthodb.org/?gene=A0A8V0XHC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941151", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRSTLLGRV", "length": 472, "header": "tr|A0A3Q2U7F8-1|A0A3Q2U7F8_CHICK Isoform 1 of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8/entry", "sequence": { "sequence": "MPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRSTLLGRV", "length": 472, "header": "tr|A0A3Q2U7F8-1|A0A3Q2U7F8_CHICK Isoform 1 of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45180984, "end_pos": 45166560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006681.1", "url": "https://www.ensembl.org/id/ENSGALT00010006681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004090.1", "url": "https://www.ensembl.org/id/ENSGALP00010004090.1" } ] } }, { "isoform_ac": "A0A8V0XBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBN7/entry", "sequence": { "sequence": "MKKAFLSAFRRKMPFIAVHFLERMPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRSTLLGRV", "length": 495, "header": "tr|A0A8V0XBN7-1|A0A3Q2U7F8_CHICK Computationally mapped isoform of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45180984, "end_pos": 45163124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006675.1", "url": "https://www.ensembl.org/id/ENSGALT00010006675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004086.1", "url": "https://www.ensembl.org/id/ENSGALP00010004086.1" } ] } }, { "isoform_ac": "A0A8V0XBP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBP2/entry", "sequence": { "sequence": "MLLESVAMYQSKLISERAVHFGTSAHAKPLPAHKQERMPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRSTLLGRV", "length": 509, "header": "tr|A0A8V0XBP2-1|A0A3Q2U7F8_CHICK Computationally mapped isoform of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45180984, "end_pos": 45088828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006682.1", "url": "https://www.ensembl.org/id/ENSGALT00010006682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004091.1", "url": "https://www.ensembl.org/id/ENSGALP00010004091.1" } ] } }, { "isoform_ac": "A0A8V0XEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEL8/entry", "sequence": { "sequence": "MPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRSTLLGRV", "length": 470, "header": "tr|A0A8V0XEL8-1|A0A3Q2U7F8_CHICK Computationally mapped isoform of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45180984, "end_pos": 45166560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006671.1", "url": "https://www.ensembl.org/id/ENSGALT00010006671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004084.1", "url": "https://www.ensembl.org/id/ENSGALP00010004084.1" } ] } }, { "isoform_ac": "A0A8V0XEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM3/entry", "sequence": { "sequence": "MPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRFVNASGQSLMHGMAATSAVAVTEGHGVVYVFVHRVAFRVMKTVQSVEITCRQR", "length": 518, "header": "tr|A0A8V0XEM3-1|A0A3Q2U7F8_CHICK Computationally mapped isoform of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45181118, "end_pos": 45166560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006679.1", "url": "https://www.ensembl.org/id/ENSGALT00010006679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004089.1", "url": "https://www.ensembl.org/id/ENSGALP00010004089.1" } ] } }, { "isoform_ac": "A0A8V0XHC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHC0/entry", "sequence": { "sequence": "MPQTPPFAAMFDSSGYNRNLYQSKEDGCGGLYYHDNNLLSGSLEALIQHLVPSVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEQQRLSEPVQDKNRIRKIAPKILQLLTEWTETFPYDFRDERMMRNLKELAQRITSGDEMYRKNVQQLLQNLLRKLATVSQYEEVLAKINATSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYGDRKKSRNLEAYVEWFNRLSYLVATEICMPVKKKHRARVIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGATQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTIPVFSDDALYLASYESESPENHIEKDRWKTLRFVSKVTHINK", "length": 475, "header": "tr|A0A8V0XHC0-1|A0A3Q2U7F8_CHICK Computationally mapped isoform of RasGEF domain family member 1B OS=Gallus gallus OX=9031 GN=RASGEF1B PE=4 SV=1 CANONICAL=A0A3Q2U7F8-1" }, "locus": { "chromosome": "4", "start_pos": 45180180, "end_pos": 45166560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006666.1", "url": "https://www.ensembl.org/id/ENSGALT00010006666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004080.1", "url": "https://www.ensembl.org/id/ENSGALP00010004080.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859744", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7F8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 312, "end_pos": 314 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U8X6-1", "uniprot_ac": "A0A3Q2U8X6", "uniprot_id": "A0A3Q2U8X6_CHICK", "mass": { "chemical_mass": 12408.0, "monoisotopic_mass": 12408.0 }, "refseq": { "ac": "XP_419699", "name": "dynein light chain Tctex-type 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419699" }, "gene_names": [ { "name": "DYNLT1", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6" } ] }, { "name": "DYNLT1", "type": "synonym", "evidence": [ { "id": "XP_419699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419699" } ] } ], "protein_names": [ { "name": "Dynein light chain Tctex-type 1", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6/entry#names_and_taxonomy" } ] }, { "name": "dynein light chain Tctex-type 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_419699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419699" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419699" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8X6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DYNLT1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6", "locus": { "chromosome": "3", "start_pos": 51758116, "end_pos": 51769040, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005503", "url": "https://www.ensembl.org/id/ENSGALG00010005503" } ] } } ], "crossref": [ { "id": "A0A3Q2U8X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019979", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019979", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21462", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21462", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421660", "url": "https://www.ncbi.nlm.nih.gov/gene/421660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U8X6", "url": "https://www.orthodb.org/?gene=A0A3Q2U8X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHV5", "url": "https://www.orthodb.org/?gene=A0A8V0XHV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XS17", "url": "https://www.orthodb.org/?gene=A0A8V0XS17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XUM1", "url": "https://www.orthodb.org/?gene=A0A8V0XUM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21255:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419699", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8X6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDFQAGEETSFVVDEVSNIIKEAIESAIGGNAYQHSKVNQWTTSVVEQSLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDNSSDGTCTVRWENKTMYCIVSAFGLAI", "length": 113, "header": "tr|A0A3Q2U8X6-1|A0A3Q2U8X6_CHICK Isoform 1 of Dynein light chain Tctex-type 1 OS=Gallus gallus OX=9031 GN=DYNLT1 PE=1 SV=1 CANONICAL=A0A3Q2U8X6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U8X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8X6/entry", "sequence": { "sequence": "MDDFQAGEETSFVVDEVSNIIKEAIESAIGGNAYQHSKVNQWTTSVVEQSLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDNSSDGTCTVRWENKTMYCIVSAFGLAI", "length": 113, "header": "tr|A0A3Q2U8X6-1|A0A3Q2U8X6_CHICK Isoform 1 of Dynein light chain Tctex-type 1 OS=Gallus gallus OX=9031 GN=DYNLT1 PE=1 SV=1 CANONICAL=A0A3Q2U8X6-1" }, "locus": { "chromosome": "3", "start_pos": 51762391, "end_pos": 51759228, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013161.1", "url": "https://www.ensembl.org/id/ENSGALT00010013161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007723.1", "url": "https://www.ensembl.org/id/ENSGALP00010007723.1" } ] } }, { "isoform_ac": "A0A8V0XHV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHV5/entry", "sequence": { "sequence": "MTAKRKKSTPEKEKEQKYTKRGKTSFVVDEVSNIIKEAIESAIGGNAYQHSKVNQWTTSVVEQSLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDNSSDGTCTVRWENKTMYCIVSAFGLAI", "length": 127, "header": "tr|A0A8V0XHV5-1|A0A3Q2U8X6_CHICK Computationally mapped isoform of Dynein light chain Tctex-type 1 OS=Gallus gallus OX=9031 GN=DYNLT1 PE=1 SV=1 CANONICAL=A0A3Q2U8X6-1" }, "locus": { "chromosome": "3", "start_pos": 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Peptide", "id": "ENSGALP00010007722.1", "url": "https://www.ensembl.org/id/ENSGALP00010007722.1" } ] } }, { "isoform_ac": "A0A8V0XUM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM1/entry", "sequence": { "sequence": "RCRFHSTVSRVCTLRLSAARSTSFVVDEVSNIIKEAIESAIGGNAYQHSKVNQWTTSVVEQSLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDNSSDGTCTVRWENKTMYCIVSAFGLAI", "length": 125, "header": "tr|A0A8V0XUM1-1|A0A3Q2U8X6_CHICK Computationally mapped isoform of Dynein light chain Tctex-type 1 OS=Gallus gallus OX=9031 GN=DYNLT1 PE=1 SV=1 CANONICAL=A0A3Q2U8X6-1" }, "locus": { "chromosome": "3", "start_pos": 51761785, "end_pos": 51759228, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013158.1", "url": "https://www.ensembl.org/id/ENSGALT00010013158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007720.1", "url": "https://www.ensembl.org/id/ENSGALP00010007720.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], 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This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040517346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7", "locus": { "chromosome": "1", "start_pos": 154462524, "end_pos": 154395941, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000784", "url": "https://www.ensembl.org/id/ENSGALG00010000784" } ] } } ], "crossref": [ { "id": "A0A3Q2U3I7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3I7", "database": 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"A0A8V0X0X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X0X7/entry", "sequence": { "sequence": "MSCGSRMKRGRKTNEANNSSSEETAEKESKRHKSVDERTTVVRSPDWGNLLQDIILQVFQYLPLLDRAHASQVCRSWNQVFHMPDLWRCFEFELNQPATSYLRATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTQFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPVTHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKYLSAVGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 439, "header": "tr|A0A8V0X0X7-1|A0A3Q2U3I7_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 3 OS=Gallus gallus OX=9031 GN=FBXL3 PE=4 SV=1 CANONICAL=A0A3Q2U3I7-1" }, "locus": { "chromosome": "1", "start_pos": 154408827, "end_pos": 154398343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001711.1", "url": "https://www.ensembl.org/id/ENSGALT00010001711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000912.1", "url": "https://www.ensembl.org/id/ENSGALP00010000912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428048", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V7A7-1", "protein_name": "F-box/LRR-repeat protein 21", "gene_name": "FBXL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKRGGGRDSDHNSSEEGTAEKSKKLRTTSEPSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 429 }, "evidence": [ { "id": "A0A3Q2U3I7", "url": "https://omabrowser.org/oma/group/A0A3Q2U3I7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F3X0-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRGGRDSDLDSPEEGTAEKRKKLRTAHECSQPCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A3Q2U3I7", "url": "https://omabrowser.org/oma/group/A0A3Q2U3I7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LNB3-1", "protein_name": "F-box and leucine-rich repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMKRGGRDSDQDSPEEGTAEKPKKPRTTHECSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 430 }, "evidence": [ { "id": "A0A3Q2U3I7", "url": "https://omabrowser.org/oma/group/A0A3Q2U3I7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C4V4-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "Fbxl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRGGRDSDQDSAEEGTAEKPKRPRTTQERSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIKHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A3Q2U3I7", "url": "https://omabrowser.org/oma/group/A0A3Q2U3I7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKT7-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "FBXL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW", "length": 428 }, "evidence": [ { "id": "A0A3Q2U3I7", "url": "https://omabrowser.org/oma/group/A0A3Q2U3I7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3I7" } ], "pmid": "" }, { "name": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UHC2-1", "uniprot_ac": "A0A3Q2UHC2", "uniprot_id": "A0A3Q2UHC2_CHICK", "mass": { "chemical_mass": 151706.0, "monoisotopic_mass": 151706.0 }, "refseq": {}, "gene_names": [ { "name": "DENND5B", "type": "recommended", "evidence": [ { "id": "A0A3Q2UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ] } ], "protein_names": [ { "name": "DENN domain containing 5B", "type": "synonym", "evidence": [ { "id": "A0A3Q2UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ], "common_name": "Chicken", "glygen_name": 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"https://www.ebi.ac.uk/interpro/entry/IPR047293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LYQMHHA", "url": "https://omabrowser.org/oma/group/LYQMHHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RPK6", "url": "https://www.orthodb.org/?gene=A0A1L1RPK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UHC2", "url": "https://www.orthodb.org/?gene=A0A3Q2UHC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y782", "url": "https://www.orthodb.org/?gene=A0A8V0Y782", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7A3", "url": "https://www.orthodb.org/?gene=A0A8V0Y7A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC44", "url": "https://www.orthodb.org/?gene=A0A8V0YC44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDF2", "url": "https://www.orthodb.org/?gene=A0A8V0YDF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFM6", "url": "https://www.orthodb.org/?gene=A0A8V0YFM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN6", "url": "https://www.orthodb.org/?gene=A0A8V0YFN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKD5", "url": "https://www.orthodb.org/?gene=A0A8V0YKD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46070:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46070:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RPK6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RPK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y782", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y782", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y782-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y782-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSGAPGPGAAPCRFAHYFVLCGIDAESGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAGCLSIRRLVLVDIVAPEPHFLSLEMQQADTQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREPSEELLLRQNSMAFWEWDQGPPPPARPPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1335, "header": "tr|A0A3Q2UHC2-1|A0A3Q2UHC2_CHICK Isoform 1 of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RPK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RPK6/entry", "sequence": { "sequence": "MSGSGAPGPGAAPCRFAHYFVLCGIDAESGLEPDELAVLYKWLEADLHGKSSDTANKASGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1291, "header": "tr|A0A1L1RPK6-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=2 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59474806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028758.1", "url": "https://www.ensembl.org/id/ENSGALT00010028758.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016545.1", "url": "https://www.ensembl.org/id/ENSGALP00010016545.1" } ] } }, { "isoform_ac": "A0A3Q2UHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2/entry", "sequence": { "sequence": "MSGSGAPGPGAAPCRFAHYFVLCGIDAESGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAGCLSIRRLVLVDIVAPEPHFLSLEMQQADTQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREPSEELLLRQNSMAFWEWDQGPPPPARPPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1335, "header": "tr|A0A3Q2UHC2-1|A0A3Q2UHC2_CHICK Isoform 1 of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59474806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028751.1", "url": "https://www.ensembl.org/id/ENSGALT00010028751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016541.1", "url": "https://www.ensembl.org/id/ENSGALP00010016541.1" } ] } }, { "isoform_ac": "A0A8V0Y782-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y782/entry", "sequence": { "sequence": "MQQSNVGVIMPSKHLWRYHKALSQGWKKDLATRGRKGSGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1270, "header": "tr|A0A8V0Y782-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59477372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028731.1", "url": "https://www.ensembl.org/id/ENSGALT00010028731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016528.1", "url": "https://www.ensembl.org/id/ENSGALP00010016528.1" } ] } }, { "isoform_ac": "A0A8V0Y7A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7A3/entry", "sequence": { "sequence": "MSETSLWRRIKQKPAQPGGNILLSMEPHPVQTGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1264, "header": "tr|A0A8V0Y7A3-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59465573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028765.1", "url": "https://www.ensembl.org/id/ENSGALT00010028765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016549.1", "url": "https://www.ensembl.org/id/ENSGALP00010016549.1" } ] } }, { "isoform_ac": "A0A8V0YC44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC44/entry", "sequence": { "sequence": "MTWTSQCAFCCFLLSFPARCMGVLSGSTAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1261, "header": "tr|A0A8V0YC44-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59476136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028738.1", "url": "https://www.ensembl.org/id/ENSGALT00010028738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016532.1", "url": "https://www.ensembl.org/id/ENSGALP00010016532.1" } ] } }, { "isoform_ac": "A0A8V0YDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF2/entry", "sequence": { "sequence": "MGVLSGSTAVLYKWLEADLHGKSSDTANKASGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1263, "header": "tr|A0A8V0YDF2-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59476196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028735.1", "url": "https://www.ensembl.org/id/ENSGALT00010028735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016530.1", "url": "https://www.ensembl.org/id/ENSGALP00010016530.1" } ] } }, { "isoform_ac": "A0A8V0YFM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM6/entry", "sequence": { "sequence": "MARSRSPWQELRYCKQSLRSISSSKMQTLQGRYKGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1266, "header": "tr|A0A8V0YFM6-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59517046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028743.1", "url": "https://www.ensembl.org/id/ENSGALT00010028743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016536.1", "url": "https://www.ensembl.org/id/ENSGALP00010016536.1" } ] } }, { "isoform_ac": "A0A8V0YFN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN6/entry", "sequence": { "sequence": "MSETSLWRRIKQKPAQPGGNILLSMEPHPVQTVLYKWLEADLHGKSSDTANKASGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1286, "header": "tr|A0A8V0YFN6-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59465573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028760.1", "url": "https://www.ensembl.org/id/ENSGALT00010028760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016547.1", "url": "https://www.ensembl.org/id/ENSGALP00010016547.1" } ] } }, { "isoform_ac": "A0A8V0YKD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD5/entry", "sequence": { "sequence": "MMLFLYFARVLYKWLEADLHGKSSDTANKASGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNRDPQLHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVCASSSCSMDSLASSIDEGDATSLAKLQRYNSYDISRDTLYVSKCICLITPLPFMQACKKFLVQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPIICQRPGPNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKLEFIQEISEVLLQFGIPPEGNLHCSDSATKLKNLVLSDLVNDKKNGNIPGNALNMYELLKGNETIARLQALAKRTGVTMEKMTITAPLAEKEKDMKLQCEEVELRDYKLNVQLREVFANRFTQLFADYEAFVIQAAPDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIISQWEEKDPFLRVFDSRIEKIRLYNVRAPALRTSNYQKCSTLKEAAQSIEQRLMKIDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWASRSATTQRRKDRLRQHSEHIGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNSKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLQYQEREEKQEHSAESPVAVGTERRKSDTGITLPTLRVSLIQDMRHVQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLAKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIVIPYRAVIIPIKKLSNAITTSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERILIGELVSSTSDEELGKQCRTPPQQKSPTTARRLSITSLTGKNTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTILLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETSDQIGDNEEALLLQRSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPLITRMYEENALLRDRMTVNSLIRVLQTLQDFNIVLEGSLIKGVDV", "length": 1263, "header": "tr|A0A8V0YKD5-1|A0A3Q2UHC2_CHICK Computationally mapped isoform of DENN domain containing 5B OS=Gallus gallus OX=9031 GN=DENND5B PE=1 SV=1 CANONICAL=A0A3Q2UHC2-1" }, "locus": { "chromosome": "1", "start_pos": 59580889, "end_pos": 59508513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028724.1", "url": "https://www.ensembl.org/id/ENSGALT00010028724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016524.1", "url": "https://www.ensembl.org/id/ENSGALP00010016524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JZJ1-1", "protein_name": "DENN domain containing 5B", "gene_name": "DENND5B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGSGAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQNDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSIDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESTTKLKNLVLKDLVNDKKNGNVSANNISMYELLKGNETIARLQALAKRTGVTVEKMDLSASLSDKEKDLKLQCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWVSRSATAQRRKDRLRQHSEHVGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQLLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRAVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSAADEDLVKQCRTPPQQKSPTMARRLSITSLTGKSTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGESGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKAVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZYN4-1", "protein_name": "DENN domain containing 5B", "gene_name": "Dennd5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGSGAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACRKFLLQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESATKLKNMVLKDLANDKKNGNVPTNNVSVYELLKGSETIARLQALAKRTGVTVGKIDFPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKMRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREPSGELLVCQNSMAFWEWDQGPTPPARLPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHVQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDMLIQKPSCKTFCHYVNAVNTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1311 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2RSQ0-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "Dennd5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHSSESATKLKNMVLKDLANDKKNGNVPNNSVSVYELLKGSETIARLQALAKRTGVTMEKIDLPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDVLIQKPSSKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MQ87-1", "protein_name": "DENN domain containing 5B", "gene_name": "DENND5B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGSGAAPGPASGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSIDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGLNELPLSDYPLREVFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESATKLKNLVLKDLVNDKKNGNVSANSISMYELLKGNETIARLQALAKRTGVTMEKMDLSASLSEKEKDLKLQCEDAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDLESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTNNNRWVSRSATAQRRKDRLRQHSDHVGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKVLSQHLKQLLSNQLLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSAADEDLVKQCRTPPQQKSPTVARRLSITSLTGKTTKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGESGLVAALEQVFHHGFKSARIFHKNVFIWDFIERAVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6NXD8-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "dennd5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSATMSGSGSAPCRFAHYFIVCGLDDETGLEPDALAALYQWLEADRQGKDPEATAAGENFDQSPLKRTFKSKVLAHYPENIECNPFDQDAVNMLCMPKGLSFRTQRDSLAPHFHSFLITREDGSRTYGFVHTFYEEVTSPQICSAMQTLHQMHQAEHNTSAQNCTSSSSSSSSSSSSSSMDSLSSSLDDVDSPSAHGGRRTCEGYDSIRDTLYVSKAMCLIAPMPFMHACKRFLAQMHRAVSCSPPPPLPLESYIYNVLYEVPLPASGRSLKFHGVYEPILCQRPGVGELPLADFPLADAFRLLGVENLVQLFTCVLLEMQILLYSQDYQRLMVVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHCIELPEDFPQFPNRSEFIQELSEVLLSFGQSPEGGSSSPEPAVMSLQTSVLEKELKSTSLRELVDDKTNGNLGGEALDVLELLQGNPTLERLQALAKRTGVKVARLEALAAGQKGDEGVGGRSPVEEEELRNAKLNVQLREVFAARFATMFADYESFVIQNSPDLESWLTNREQMHNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIMSQWEEKEPLLRVFDGRIEKARLYNVRAPSLRSSVYQKCTFLKESAQAIEQRLRKIDHTAIHPHLLDMKIGQGKYQQGFFPKLQADVLASGPTSNKWSNRTCSTQRRVERHRQQNEHLVLDNELKEKYMQEARNLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECKMKTKRMLVEKMGREAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQAREEKNEQQLESPVSNGQERRKTESSVGLPGLRVSVIQDMRHIQNMAEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQALTKKLYKRYAFLRCEEEKEQFLFHLLSLNAVDYFCFTSVFTTIMIPYRAVIIPIKKLSNAMTTSNPWLCVSGELGDSGILQITKNILEMTFDCQNLGKLTTVQLGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERVLIGEFVVPCGDDEGGRGSKTPPLQRSPSQIRRISITSLTGKGNKPTTVQIQESIGEAVNNIIKHFHKPEKERGSLTVLLCGEGGLVWALEQFFHHGFRSARIFQKNVFVWDFFERIVAFMENRDQTGDLQESPEPLSLNSESLCRYVNAINNMPRNIGKDGKFQLLVCLGARDRLLPQWLPLLAESPVITRMYEENALLRDKLTVSSLLGVLETLHDFPITLETSLTKSVEL", "length": 1311 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZUT9-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "DENND5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGSCAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEGSLHCSESTSKLKNMVLKDLVNDKKNGNVCTNNISMYELLKGNETIARLQALAKRTGVAVEKMDLSASLGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSASDEDLVKQCRTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "A0A3Q2UHC2", "url": "https://omabrowser.org/oma/group/A0A3Q2UHC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of triglyceride transport", "id": "GO:1905885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905885", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UHC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 446, "end_pos": 448 }, { "start_pos": 829, "end_pos": 831 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U2D5-1", "uniprot_ac": "A0A3Q2U2D5", "uniprot_id": "A0A3Q2U2D5_CHICK", "mass": { "chemical_mass": 64247.0, "monoisotopic_mass": 64247.0 }, "refseq": {}, "gene_names": [ { "name": "THAP4", "type": "recommended", "evidence": [ { "id": "A0A3Q2U2D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ] } ], "protein_names": [ { "name": "THAP domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A3Q2U2D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo, possibly modulating the transcriptional activity residing in the N-terminal region.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E3#function" }, { "database": "UniProtKB", "id": "ARBA00054954", "url": "https://www.uniprot.org/uniprotkb/ARBA00054954#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THAP4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5", "locus": { "chromosome": "9", "start_pos": 4480757, "end_pos": 4466499, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024928", "url": "https://www.ensembl.org/id/ENSGALG00010024928" } ] } } ], "crossref": [ { "id": "A0A3Q2U2D5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U2D5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006283", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07828", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07828", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429271", "url": "https://www.ncbi.nlm.nih.gov/gene/429271", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U2D5", "url": "https://www.orthodb.org/?gene=A0A3Q2U2D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZVR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8E3", "url": "https://www.orthodb.org/?gene=A0A8V1A8E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15854:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15854:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "63116", "url": "https://www.rhea-db.org/rhea/63116", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVICCAAANCSNRQGKALRGAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDSFSRRLEDQHRLLKPTAVPTIFQLAEKKRDNLDYVRSRRKIASQVPLQDGEGPREGGCEVVQRTSSPEQDLMVMQGTDEMEEVTLQAEIGSMSEEEEHLHGQLEGPRRRTLGDSLVAKPGPQKKSDRSSAEGCPKGSWTGSWVADRSGISVDDFTPPASGACKFIGSLHSYSFSSKHTRERPSFPKEQLERKRPKRDVEPSCSSNLTGHDKTVAEDSPTSSLTATPQKPSQSLSASPADLTPQPAAEAVVGRKGDTDANPMSINEVIMSASGACKLIDSLHSYCFSSRQSKSQVCCLREQVEKKNGELKLLRQRISRSDSQVRKLKEKLDELKRISIPYLNSLLSQDCETPQLNPVMEPLSWMLGTWLSDPPGDGTFPTMKPFQYLEEVHISHVGQPMLNFSFNAFHPDTRKPMHRECGFIRLKPDTNKVAFISAQNTGLVEVEEGEVNGQELSIASHSIARISFAKKPHVEQITRKFRLNSDGKLEQTVSMATTTQPMTQHLHITYKKVTP", "length": 575, "header": "tr|A0A3Q2U2D5-1|A0A3Q2U2D5_CHICK Isoform 1 of THAP domain containing 4 OS=Gallus gallus OX=9031 GN=THAP4 PE=4 SV=1 CANONICAL=A0A3Q2U2D5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U2D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5/entry", "sequence": { "sequence": "MVICCAAANCSNRQGKALRGAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDSFSRRLEDQHRLLKPTAVPTIFQLAEKKRDNLDYVRSRRKIASQVPLQDGEGPREGGCEVVQRTSSPEQDLMVMQGTDEMEEVTLQAEIGSMSEEEEHLHGQLEGPRRRTLGDSLVAKPGPQKKSDRSSAEGCPKGSWTGSWVADRSGISVDDFTPPASGACKFIGSLHSYSFSSKHTRERPSFPKEQLERKRPKRDVEPSCSSNLTGHDKTVAEDSPTSSLTATPQKPSQSLSASPADLTPQPAAEAVVGRKGDTDANPMSINEVIMSASGACKLIDSLHSYCFSSRQSKSQVCCLREQVEKKNGELKLLRQRISRSDSQVRKLKEKLDELKRISIPYLNSLLSQDCETPQLNPVMEPLSWMLGTWLSDPPGDGTFPTMKPFQYLEEVHISHVGQPMLNFSFNAFHPDTRKPMHRECGFIRLKPDTNKVAFISAQNTGLVEVEEGEVNGQELSIASHSIARISFAKKPHVEQITRKFRLNSDGKLEQTVSMATTTQPMTQHLHITYKKVTP", "length": 575, "header": "tr|A0A3Q2U2D5-1|A0A3Q2U2D5_CHICK Isoform 1 of THAP domain containing 4 OS=Gallus gallus OX=9031 GN=THAP4 PE=4 SV=1 CANONICAL=A0A3Q2U2D5-1" }, "locus": { "chromosome": "9", "start_pos": 4480550, "end_pos": 4466992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060884.1", "url": "https://www.ensembl.org/id/ENSGALT00010060884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037641.1", "url": "https://www.ensembl.org/id/ENSGALP00010037641.1" } ] } }, { "isoform_ac": "A0A8V0ZVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVR0/entry", "sequence": { "sequence": "MGAARREYAPRNSGGRARPSCCTEAAGPRPSAPGKAAPDRLGQAGGGSSRSSGGGRPAARKRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDSFSRRLEDQHRLLKPTAVPTIFQLAEKKRDNLDYVRSRRKIASQVPLQDGEGPREGGCEVVQRTSSPEQDLMVMQGTDEMEEVTLQAEIGSMSEEEEHLHGQLEGPRRRTLGDSLVAKPGPQKKSDRSSAEGCPKGSWTGSWVADRSGISVDDFTPPASGACKFIGSLHSYSFSSKHTRERPSFPKEQLERKRPKRDVEPSCSSNLTGHDKTVAEDSPTSSLTATPQKPSQSLSASPADLTPQPAAEAVVGRKGDTDANPMSINEVIMSASGACKLIDSLHSYCFSSRQSKSQVCCLREQVEKKNGELKLLRQRISRSDSQVRKLKEKLDELKRISIPYLNSLLSQDCETPQLNPVMEPLSWMLGTWLSDPPGDGTFPTMKPFQYLEEVHISHVGQPMLNFSFNAFHPDTRKPMHRECGFIRLKPDTNKVAFISAQNTGLVEVEEGEVNGQELSIASHSIARISFAKKPHVEQIALRCSWKYCTASLLIFSWSFQKPFRRLQDEKGSLR", "length": 608, "header": "tr|A0A8V0ZVR0-1|A0A3Q2U2D5_CHICK Computationally mapped isoform of THAP domain containing 4 OS=Gallus gallus OX=9031 GN=THAP4 PE=4 SV=1 CANONICAL=A0A3Q2U2D5-1" }, "locus": { "chromosome": "9", "start_pos": 4478890, "end_pos": 4466564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060886.1", "url": "https://www.ensembl.org/id/ENSGALT00010060886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037643.1", "url": "https://www.ensembl.org/id/ENSGALP00010037643.1" } ] } }, { "isoform_ac": "A0A8V1A8E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8E3/entry", "sequence": { "sequence": "MHLQETPQLNPVMEPLSWMLGTWLSDPPGDGTFPTMKPFQYLEEVHISHVGQPMLNFSFNAFHPDTRKPMHRECGFIRLKPDTNKVAFISAQNTGLVEVEEGEVNGQELSIASHSIARISFAKKPHVEQITRKFRLNSDGKLEQTVSMATTTQPMTQHLHITYKKVTP", "length": 168, "header": "tr|A0A8V1A8E3-1|A0A3Q2U2D5_CHICK Computationally mapped isoform of THAP domain containing 4 OS=Gallus gallus OX=9031 GN=THAP4 PE=4 SV=1 CANONICAL=A0A3Q2U2D5-1" }, "locus": { "chromosome": "9", "start_pos": 4480550, "end_pos": 4475663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060882.1", "url": "https://www.ensembl.org/id/ENSGALT00010060882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037639.1", "url": "https://www.ensembl.org/id/ENSGALP00010037639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "nitric oxide binding", "id": "GO:0070026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070026", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "peroxynitrite isomerase activity", "id": "GO:0062213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062213", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nitrate metabolic process", "id": "GO:0042126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042126", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" }, { "name": "tyrosine metabolic process", "id": "GO:0006570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006570", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2D5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": 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"end_pos": 48 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TWA5-1", "uniprot_ac": "A0A3Q2TWA5", "uniprot_id": "A0A3Q2TWA5_CHICK", "mass": { "chemical_mass": 111135.0, "monoisotopic_mass": 111135.0 }, "refseq": { "ac": "XP_040504942", "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3 isoform X21", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504942" }, "gene_names": [ { "name": "GARNL3", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5" } ] }, { "name": "GARNL3", "type": "synonym", "evidence": [ { "id": "XP_040504942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504942" } ] } ], "protein_names": [ { "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5/entry#names_and_taxonomy" } ] }, { "name": "GTPase-activating Rap/Ran-GAP domain-like protein 3 isoform X21", "type": "synonym", "evidence": [ { "id": "XP_040504942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504942" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GARNL3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5", "locus": { "chromosome": "17", "start_pos": 11058454, "end_pos": 11011006, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028739", "url": "https://www.ensembl.org/id/ENSGALG00010028739" } ] } } ], "crossref": [ { "id": "A0A3Q2TWA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000847", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000847", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417087", "url": "https://www.ncbi.nlm.nih.gov/gene/417087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TWA5", "url": "https://www.orthodb.org/?gene=A0A3Q2TWA5", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3C8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U522", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U522", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U522-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U522-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEVSGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGLLDEPIPKTEGAQKQKKVSRRQSDPKQGAVRSTSSDRIISASFESYSEGRHLSTSSDPDSVANREESSPFSYPFHLTSLYDEDIIDLK", "length": 985, "header": "tr|A0A3Q2TWA5-1|A0A3Q2TWA5_CHICK Isoform 1 of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TWA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5/entry", "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEVSGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGLLDEPIPKTEGAQKQKKVSRRQSDPKQGAVRSTSSDRIISASFESYSEGRHLSTSSDPDSVANREESSPFSYPFHLTSLYDEDIIDLK", "length": 985, "header": "tr|A0A3Q2TWA5-1|A0A3Q2TWA5_CHICK Isoform 1 of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11050815, "end_pos": 11014786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069547.1", "url": "https://www.ensembl.org/id/ENSGALT00010069547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042808.1", "url": "https://www.ensembl.org/id/ENSGALP00010042808.1" } ] } }, { "isoform_ac": "A0A3Q2U3C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3C8/entry", "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEVSGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGLLDEPIPKTEGAQKQKKVSRRQSDPKQGAVRSTSSDRIISASFESYSEGRHLSTSSDPDSVANREESSPFSYPFHLTSLYDEDIIDLK", "length": 994, "header": "tr|A0A3Q2U3C8-1|A0A3Q2U3C8_CHICK Computationally mapped isoform of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11050815, "end_pos": 11014786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069550.1", "url": "https://www.ensembl.org/id/ENSGALT00010069550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042811.1", "url": "https://www.ensembl.org/id/ENSGALP00010042811.1" } ] } }, { "isoform_ac": "A0A3Q2U522-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U522/entry", "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGLLDEPIPKTEGAQKQKKVSRRQSDPKQGAVRSTSSDRTGDSTIRCRCYSWSPQIATLDVP", "length": 964, "header": "tr|A0A3Q2U522-1|A0A3Q2U522_CHICK Computationally mapped isoform of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11057450, "end_pos": 11014786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069553.1", "url": "https://www.ensembl.org/id/ENSGALT00010069553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042814.1", "url": "https://www.ensembl.org/id/ENSGALP00010042814.1" } ] } }, { "isoform_ac": "A0A8V1AA11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA11/entry", "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNDDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGKLPLFFSVYISYH", "length": 884, "header": "tr|A0A8V1AA11-1|A0A3Q2TWA5_CHICK Computationally mapped isoform of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11049497, "end_pos": 11014786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069546.1", "url": "https://www.ensembl.org/id/ENSGALT00010069546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042807.1", "url": "https://www.ensembl.org/id/ENSGALP00010042807.1" } ] } }, { "isoform_ac": "A0A8V1AA16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA16/entry", "sequence": { "sequence": "MPFSDAPGSFTASCCWCPAPLRVLCSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLGLLDEPIPKTEGAQKQKKVSRRQSDPKQGAVRSTSSDRIISASFESYSEGRHLSTSSDPDSVANREESSPFSYPFHLTSLYDEDIIDLK", "length": 998, "header": "tr|A0A8V1AA16-1|A0A3Q2TWA5_CHICK Computationally mapped isoform of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11050815, "end_pos": 11011106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069551.1", "url": "https://www.ensembl.org/id/ENSGALT00010069551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042812.1", "url": "https://www.ensembl.org/id/ENSGALP00010042812.1" } ] } }, { "isoform_ac": "A0A8V1AJS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJS0/entry", "sequence": { "sequence": "MELSSAEAVSTRFLGLTQRSVSEDLGCRRGEFSRKHYGSVELLISSDADGAIQRAGRFRVENGSSDENTGYTPGTWHRTDVHLENPEYYTRWYFKYFLGKVHQNYIGTDSEKNPFFLSVVLSDQNNQRVPQYHSILWRKTGTQKICLPYSPTKTLSVKSILSAMSLEKFEKGPREIFHPDIQKDLLVLEEQEGSVNFKFGVLYAKDGQLTDDEMFSNETGSESFQRFLHLLGDTITLKGWTGYRGGLDTKNDTTGTFSIYTVYQGHEIMFHVSTMLPYSRENKQQVERKRHIGNDIVTIVFQEGEETAPAFKPSMIRSHFTHIFALVRYNKQNDSYRLKIFSEESVPLFGPPLPSPPVFTNHQEFRDFVLVKLINGEKATLETPTFSQKRQRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPDSPKSTRKKEEARQAEFVRLGQALKLKTGVKGDAPTTLATTSFCKKEPWESQSFCSNFPHEVVCADSWGQSLLVSTDAGILLIDDGQTTVQVFDKTLQIKQMHVLEALDYLIARTDKGKDSRLLVFRLSSVQKDIETKQVIRSKYDCRENKLERTKGCHLYAINTHHSSELRIVVAIRNKLLLITKKYNPCNSLTGSSLSLSESPVEEFQYIREICLSDPPVVMTLVDGPTGDSDNMICVAYRHQFDLVNESTGESYRLHHIEANKVNFVAAIDVYEDGEAGLLLCYNYVCQYRKVYPFNGGSPLIQPSAYDFHFSWNQVPYAVVCAFPYILAFTTDSIEIRLVVNGNLVHTAVVPELQLVASRSDIYFKATAAVSGSSHSSSKEMSSRSSPQTPTAYDMLECSLSSSEVSGEVACKNLYKIPLSNLVGRSIERPLKSPLTPKVVTTPTSSGITSLPVTHSLSLSRMEIKEIANRTRKELLE", "length": 906, "header": "tr|A0A8V1AJS0-1|A0A3Q2TWA5_CHICK Computationally mapped isoform of GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus OX=9031 GN=GARNL3 PE=3 SV=1 CANONICAL=A0A3Q2TWA5-1" }, "locus": { "chromosome": "17", "start_pos": 11050663, "end_pos": 11014786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069549.1", "url": "https://www.ensembl.org/id/ENSGALT00010069549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042810.1", "url": "https://www.ensembl.org/id/ENSGALP00010042810.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 646, "start_aa": "Thr", "end_pos": 646, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr646", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 889, "end_pos": 891, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 646 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 889, "end_pos": 891 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RWB5-1", "uniprot_ac": "A0A1L1RWB5", "uniprot_id": "A0A1L1RWB5_CHICK", "mass": { "chemical_mass": 55126.0, "monoisotopic_mass": 55126.0 }, "refseq": { "ac": "XP_424748", "name": "spliceosome-associated protein CWC27 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424748" }, "gene_names": [ { "name": "CWC27", "type": "recommended", "evidence": [ { "id": "A0A1L1RWB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ] }, { "name": "CWC27", "type": "synonym", "evidence": [ { "id": "XP_424748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424748" } ] } ], "protein_names": [ { "name": "Spliceosome-associated protein CWC27 homolog", "type": "recommended", "evidence": [ { "id": "A0A1L1RWB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5/entry#names_and_taxonomy" } ] }, { "name": "Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog", "type": "synonym", "evidence": [ { "id": "A0A1L1RWB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5/entry#names_and_taxonomy" } ] }, { "name": "spliceosome-associated protein CWC27 homolog", "type": "synonym", "evidence": [ { "id": "XP_424748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424748" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_424748.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CWC27", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5", "locus": { "chromosome": "Z", "start_pos": 20879249, "end_pos": 20763301, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012154", "url": "https://www.ensembl.org/id/ENSGALG00010012154" } ] } } ], "crossref": [ { "id": "A0A1L1RWB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RWB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014747", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427159", "url": "https://www.ncbi.nlm.nih.gov/gene/427159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427159", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDWYDVY", "url": "https://omabrowser.org/oma/group/DDWYDVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWB5", "url": "https://www.orthodb.org/?gene=A0A1L1RWB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLD5", "url": "https://www.orthodb.org/?gene=A0A8V0YLD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNIYIQEPPTNGKVLLRTTAGDIDIELWSKEAPKACRNFIQLCMEEYYNNTIFHRVVPGFIVQGGDPTGTGSGGDSIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTIYNMLRLAEVEVDKEERPLSPHKIRSSEVLFNPFDDIVPRPNRKLKKEKPEEEDKKAKVKGTKNFNLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPAVKSDAANEESYLSEEEDENDEDVDSAEGEAASNERFQMKERVAKKLKMDTNETVKLQLPEEETKTEKKTTSRSEELRKEARQLKRELLEAKQKKEEQTLKPKEKEEEEPAPNSVVEEYLQEKRKYEDKRKQQPKKGVSREDQTLALLDRFKSKLTQAIEETPENEVSESEIDTDEGWMSHVLQFEDRSRKVKDASMQDEDTFEIYDPRNPVTKRRREESKKIMREKKERR", "length": 477, "header": "tr|A0A1L1RWB5-1|A0A1L1RWB5_CHICK Isoform 1 of Spliceosome-associated protein CWC27 homolog OS=Gallus gallus OX=9031 GN=CWC27 PE=1 SV=2 CANONICAL=A0A1L1RWB5-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5/entry", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLRTTAGDIDIELWSKEAPKACRNFIQLCMEEYYNNTIFHRVVPGFIVQGGDPTGTGSGGDSIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTIYNMLRLAEVEVDKEERPLSPHKIRSSEVLFNPFDDIVPRPNRKLKKEKPEEEDKKAKVKGTKNFNLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPAVKSDAANEESYLSEEEDENDEDVDSAEGEAASNERFQMKERVAKKLKMDTNETVKLQLPEEETKTEKKTTSRSEELRKEARQLKRELLEAKQKKEEQTLKPKEKEEEEPAPNSVVEEYLQEKRKYEDKRKQQPKKGVSREDQTLALLDRFKSKLTQAIEETPENEVSESEIDTDEGWMSHVLQFEDRSRKVKDASMQDEDTFEIYDPRNPVTKRRREESKKIMREKKERR", "length": 477, "header": "tr|A0A1L1RWB5-1|A0A1L1RWB5_CHICK Isoform 1 of Spliceosome-associated protein CWC27 homolog OS=Gallus gallus OX=9031 GN=CWC27 PE=1 SV=2 CANONICAL=A0A1L1RWB5-1" }, "locus": { "chromosome": "Z", "start_pos": 20876066, "end_pos": 20763412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029159.1", "url": "https://www.ensembl.org/id/ENSGALT00010029159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016906.1", "url": "https://www.ensembl.org/id/ENSGALP00010016906.1" } ] } }, { "isoform_ac": "A0A8V0YLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD5/entry", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLRTTAGDIDIELWSKEAPKACRNFIQLCMEEYYNNTIFHRVVPGFIVQGGDPTGTGSGGDSIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTIYNMLRLAEVEVDKEERPLSPHKIRSSEVLFNPFDDIVPRPNRKLKKEKPEEEDKKAKVKGTKNFNLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPAVKSDAANEESYLSEEEDENDEDVDSAEGEAASNERFQMKERVAKKLKMDTNETVKLQLPEEETKTEKKTTSRRWSSDATHFYEELRKEARQLKRELLEAKQKKEEQTLKPKEKEEEEPAPNSVVEEYLQEKRKYEDKRKQQPKKGVSREDQTLALLDRFKSKLTQAIEETPENEVSESEIDTDEGWMSHVLQFEDRSRKVKDASMQDEDTFEIYDPRNPVTKRRREESKKIMREKKERR", "length": 486, "header": "tr|A0A8V0YLD5-1|A0A1L1RWB5_CHICK Computationally mapped isoform of Spliceosome-associated protein CWC27 homolog OS=Gallus gallus OX=9031 GN=CWC27 PE=1 SV=1 CANONICAL=A0A1L1RWB5-1" }, "locus": { "chromosome": "Z", "start_pos": 20876066, "end_pos": 20763412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029152.1", "url": "https://www.ensembl.org/id/ENSGALT00010029152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016901.1", "url": "https://www.ensembl.org/id/ENSGALP00010016901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427159", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MBE0-1", "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "CWC27", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESIYGVPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNPHKIRSCEVLFNPFDDIIPREIKKPKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPAVESERGDAAEDSDDDGEYEGAEHDEYVDGDEKNQMRERIAKKLKKDTSENVKRAGEGEVEKKPVSRSEELRKEARQLKRELLAAKQKKAENSAIQAEKRSEEEEAAPDGAVAEYRREKQKYEALRKQQAKTGTSREDQTLALLNQFKSKLTQAIAETPENDISETEVEDDEGWMSHVLQFEDKSRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLMREKKERR", "length": 473 }, "evidence": [ { "id": "A0A1L1RWB5", "url": "https://omabrowser.org/oma/group/A0A1L1RWB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TKY6-1", "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "Cwc27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNPHRIKSCEVLFNPFDDITPREIKKPKNEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGRSKSSHDLLKDDPHLSSVPAVESEKDDATGDLEDDGEDDSAERDEYMEDDEKNLMRERIAKRLKKDASASVKSAGDGEKKPASRSEELRKEARQLKRELLAAKQKKETAIKVEEGREEEEAAPDGAVAEYRREKQKYEALRKQQPKKGTSREDQTLALLSQFKSKLTQAITETPENSVPEAEVEDDEGWMSHVLQFEDKTRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLLREKKERR", "length": 469 }, "evidence": [ { "id": "A0A1L1RWB5", "url": "https://omabrowser.org/oma/group/A0A1L1RWB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIB2-1", "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "Cwc27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESVYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLTEVDIDDEERPRNPHRIKSCEVLFNPFDDIIPREIKKPKKEKAEEEIKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGRSKSSHDLLKDDPHLSSVPAVESEKDDATGDLEDDAEDDSVEHDGSMEEDEKNLMRERIAKRLKKDASANVKSAGDGEKKPASRSEELRKEARQLKRELLAAKQKKESATKAEKGSEEEEAVPDGPVAEYRREKQKYEALRKQQPKKGTSREDQTLALLSQFKSKLTQAITEMPENCAEAEVEDDEGWMSHVLQFEDKTRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLLREKKERR", "length": 468 }, "evidence": [ { "id": "A0A1L1RWB5", "url": "https://omabrowser.org/oma/group/A0A1L1RWB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UX04-1", "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "CWC27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRLSEVDIDDDERPHNPHKIKSCEVLFNPFDDIIPREIKRLKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSSHDLLKDDPHLSSVPVVESEKGDAPDLVDDGEDESAEHDEYIDGDEKNLMRERIAKKLKKDTSANVKSAGEGEVEKKSVSRSEELRKEARQLKRELLAAKQKKVENAAKQAEKRSEEEEAPPDGAVAEYRREKQKYEALRKQQSKKGTSREDQTLALLNQFKSKLTQAIAETPENDIPETEVEDDEGWMSHVLQFEDKSRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLMREKKERR", "length": 472 }, "evidence": [ { "id": "A0A1L1RWB5", "url": "https://omabrowser.org/oma/group/A0A1L1RWB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTN7-1", "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "Dmel\\CG10907", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNIYIQEPPTSGKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVKGFIVQGGDPNGDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKITGDTIYNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILSQPSTKSKKTKKERQGVKNFGLLSFGEEAEGDEEETNVYVKQNAGKAKSLHDVTDDPKLSKEPIRVPKVEKADIEEHLSDDCPEDSVKDKPSTASSDLIKMKLSKRSKSGADKKVQPVEEKSDSEDDEDVLLTREEEQSRKVSEEKSKIREEIASLKKQYQMDKQSKDKLVNGQEKAAKSNEIKGSSENHYINDFIESKEKYTAKVKLQPKGQSREAFTLSLLSKFRTKLDNLKQKSSSDDGESEPKDIDDRVVEQEIIGDDWLSHTLNFNSTTPVLAKDANKKGDDWYDAYDPRNPLNKRKRGETGSSKSSSGKSKSSKRDF", "length": 502 }, "evidence": [ { "id": "A0A1L1RWB5", "url": "https://omabrowser.org/oma/group/A0A1L1RWB5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWB5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RWB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWB5" }, { "id": "PS50072", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase cyclophilin-type", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 166, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZI78-1", "uniprot_ac": "Q5ZI78", "uniprot_id": "TFIP8_CHICK", "mass": { "chemical_mass": 21776.0, "monoisotopic_mass": 21776.0 }, "refseq": { "ac": "NP_001026612", "name": "tumor necrosis factor alpha-induced protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612" }, "gene_names": [ { "name": "TNFAIP8", "type": "recommended", "evidence": [ { "id": "Q5ZI78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ] }, { "name": "RCJMB04_29h8", "type": "synonym", "evidence": [ { "id": "Q5ZI78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ] }, { "name": "TNFAIP8", "type": "synonym", "evidence": [ { "id": "NP_001026612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612" } ] } ], "protein_names": [ { "name": "Tumor necrosis factor alpha-induced protein 8", "type": "recommended", "evidence": [ { "id": "Q5ZI78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78/entry#names_and_taxonomy" } ] }, { "name": "TNF alpha-induced protein 8", "type": "synonym", "evidence": [ { "id": "Q5ZI78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78/entry#names_and_taxonomy" } ] }, { "name": "tumor necrosis factor alpha-induced protein 8", "type": "synonym", "evidence": [ { "id": "NP_001026612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612" } ] }, { "name": "tumor necrosis factor, alpha-induced protein 8", "type": "synonym", "evidence": [ { "id": "NP_001026612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720906.1, SRR12888532.60868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000096.1. On Aug 8, 2005 this sequence version replaced XP_424957.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612" } ] }, { "annotation": "Acts as a negative mediator of apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNFAIP8", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78", "locus": { "chromosome": "Z", "start_pos": 72156339, "end_pos": 72202549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009360", "url": "https://www.ensembl.org/id/ENSGALG00010009360" } ] } } ], "crossref": [ { "id": "Q5ZI78", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027761", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027761", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427384", "url": "https://www.ncbi.nlm.nih.gov/gene/427384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427384", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427384", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XX23", "url": "https://www.orthodb.org/?gene=A0A8V0XX23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1K3", "url": "https://www.orthodb.org/?gene=A0A8V0Y1K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3A6", "url": "https://www.orthodb.org/?gene=A0A8V0Y3A6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3B1", "url": "https://www.orthodb.org/?gene=A0A8V0Y3B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3C1", "url": "https://www.orthodb.org/?gene=A0A8V0Y3C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5L5", "url": "https://www.orthodb.org/?gene=A0A8V0Y5L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5M9", "url": "https://www.orthodb.org/?gene=A0A8V0Y5M9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5N4", "url": "https://www.orthodb.org/?gene=A0A8V0Y5N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI78", "url": "https://www.orthodb.org/?gene=Q5ZI78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12757:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12757:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05527", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05527", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI78", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI78", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1483255", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483255", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XX23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI78-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 188, "header": "sp|Q5ZI78-1|TFIP8_CHICK Isoform 1 of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XX23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX23/entry", "sequence": { "sequence": "MRFVLCFAWSAEAAEGQIYSELSALNRRAEVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 218, "header": "tr|A0A8V0XX23-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72198768, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022304.1", "url": "https://www.ensembl.org/id/ENSGALT00010022304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012826.1", "url": "https://www.ensembl.org/id/ENSGALP00010012826.1" } ] } }, { "isoform_ac": "A0A8V0Y1K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1K3/entry", "sequence": { "sequence": "MCPCERSPLVLQEISKCATAGPALCFTYRKLQTILQACLHLKLATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 230, "header": "tr|A0A8V0Y1K3-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72167903, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022315.1", "url": "https://www.ensembl.org/id/ENSGALT00010022315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012835.1", "url": "https://www.ensembl.org/id/ENSGALP00010012835.1" } ] } }, { "isoform_ac": "A0A8V0Y3A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3A6/entry", "sequence": { "sequence": "MVYHYGIVQSFSFPHTLLLHKTPEVAEECKRKAAQEDPGIITEGKCLSFEHSESIDSRVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 246, "header": "tr|A0A8V0Y3A6-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72196363, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022295.1", "url": "https://www.ensembl.org/id/ENSGALT00010022295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012817.1", "url": "https://www.ensembl.org/id/ENSGALP00010012817.1" } ] } }, { "isoform_ac": "A0A8V0Y3B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3B1/entry", "sequence": { "sequence": "MKIPGRRVFSPSENTARGAEGCSQNSKLAPQRRRNLEEIMSVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 229, "header": "tr|A0A8V0Y3B1-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72167476, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022300.1", "url": "https://www.ensembl.org/id/ENSGALT00010022300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012822.1", "url": "https://www.ensembl.org/id/ENSGALP00010012822.1" } ] } }, { "isoform_ac": "A0A8V0Y3C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3C1/entry", "sequence": { "sequence": "MLVQCVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 193, "header": "tr|A0A8V0Y3C1-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72197959, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022311.1", "url": "https://www.ensembl.org/id/ENSGALT00010022311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012833.1", "url": "https://www.ensembl.org/id/ENSGALP00010012833.1" } ] } }, { "isoform_ac": "A0A8V0Y5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5L5/entry", "sequence": { "sequence": "MHNQQLLAREVRVSVEVLLLFQTAAGVLAPKGAESPEQLSPDLLNSQTFPFKIPTLLFFLSSFPFFFFSSSIFQEVCLQLRRAHLGCWCPFAMSLEADESREVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 290, "header": "tr|A0A8V0Y5L5-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72169070, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022297.1", "url": "https://www.ensembl.org/id/ENSGALT00010022297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012818.1", "url": "https://www.ensembl.org/id/ENSGALP00010012818.1" } ] } }, { "isoform_ac": "A0A8V0Y5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M9/entry", "sequence": { "sequence": "MSPSYKHLMATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 196, "header": "tr|A0A8V0Y5M9-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72190791, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022313.1", "url": "https://www.ensembl.org/id/ENSGALT00010022313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012834.1", "url": "https://www.ensembl.org/id/ENSGALP00010012834.1" } ] } }, { "isoform_ac": "A0A8V0Y5N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N4/entry", "sequence": { "sequence": "MRSAGVATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 193, "header": "tr|A0A8V0Y5N4-1|TFIP8_CHICK Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72197045, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022320.1", "url": "https://www.ensembl.org/id/ENSGALT00010022320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012839.1", "url": "https://www.ensembl.org/id/ENSGALP00010012839.1" } ] } }, { "isoform_ac": "Q5ZI78-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78/entry#Q5ZI78-1", "sequence": { "sequence": "MATDVFNSKSLAIQAQKKILGKMVSKSIATTLIDDTSSDVLDELYRVTKEYTQNKKEAEKIIKNLIKIVLKLAILYRNNQFNQDEIALMEKFKKKVHQLAKTVVSFHQVDYTFDRNFLSKLLNDCRELLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGPYKLHLQKLCDGVNRMLDEGNI", "length": 188, "header": "sp|Q5ZI78-1|TFIP8_CHICK Isoform 1 of Tumor necrosis factor alpha-induced protein 8 OS=Gallus gallus OX=9031 GN=TNFAIP8 PE=2 SV=1 CANONICAL=Q5ZI78-1" }, "locus": { "chromosome": "Z", "start_pos": 72159602, "end_pos": 72157580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022291.1", "url": "https://www.ensembl.org/id/ENSGALT00010022291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012815.1", "url": "https://www.ensembl.org/id/ENSGALP00010012815.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:427384", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427384", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483255", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483255", "resource": "Reactome", "description": "PI Metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "id": "GO:0043027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI78", "url": "https://www.uniprot.org/uniprotkb/Q5ZI78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI78-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 188, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI78-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI78" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZMM3-1", "uniprot_ac": "Q5ZMM3", "uniprot_id": "RHG15_CHICK", "mass": { "chemical_mass": 54610.0, "monoisotopic_mass": 54610.0 }, "refseq": { "ac": "NP_001008476", "name": "rho GTPase-activating protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476" }, "gene_names": [ { "name": "ARHGAP15", "type": "recommended", "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ] }, { "name": "ARHGAP15", "type": "synonym", "evidence": [ { "id": "NP_001008476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476" } ] }, { "name": "RCJMB04_1j23", "type": "synonym", "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 15", "type": "recommended", "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3/entry#names_and_taxonomy" } ] }, { "name": "ArhGAP15", "type": "synonym", "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 15", "type": "synonym", "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 15", "type": "synonym", "evidence": [ { "id": "NP_001008476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476" } ] }, { "name": "rho-type GTPase-activating protein 15", "type": "synonym", "evidence": [ { "id": "NP_001008476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719361.1, ERR2365563.108896.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Dec 16, 2004 this sequence version replaced XP_422148.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476" } ] }, { "annotation": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP15", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3", "locus": { "chromosome": "7", "start_pos": 32639342, "end_pos": 32311141, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009373", "url": "https://www.ensembl.org/id/ENSGALG00010009373" } ] } } ], "crossref": [ { "id": "Q5ZMM3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012421", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424303", "url": "https://www.ncbi.nlm.nih.gov/gene/424303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424303", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHNQWED", "url": "https://omabrowser.org/oma/group/DHNQWED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX54", "url": "https://www.orthodb.org/?gene=A0A8V0XX54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX59", "url": "https://www.orthodb.org/?gene=A0A8V0XX59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX64", "url": "https://www.orthodb.org/?gene=A0A8V0XX64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5R4", "url": "https://www.orthodb.org/?gene=A0A8V0Y5R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA87", "url": "https://www.orthodb.org/?gene=A0A8V0YA87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMM3", "url": "https://www.orthodb.org/?gene=Q5ZMM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMM3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMM3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001008476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XX54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMM3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 475, "header": "sp|Q5ZMM3-1|RHG15_CHICK Isoform 1 of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XX54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX54/entry", "sequence": { "sequence": "MYQTVEVSPVAMERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 486, "header": "tr|A0A8V0XX54-1|RHG15_CHICK Computationally mapped isoform of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638247, "end_pos": 32335273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022352.1", "url": "https://www.ensembl.org/id/ENSGALT00010022352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012856.1", "url": "https://www.ensembl.org/id/ENSGALP00010012856.1" } ] } }, { "isoform_ac": "A0A8V0XX59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX59/entry", "sequence": { "sequence": "MTSIGPSQPQPFCHTLTSCYFLPHLWLKGIFWKKMIYWDQERIKVSPVAMERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 524, "header": "tr|A0A8V0XX59-1|RHG15_CHICK Computationally mapped isoform of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638247, "end_pos": 32334683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022357.1", "url": "https://www.ensembl.org/id/ENSGALT00010022357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012861.1", "url": "https://www.ensembl.org/id/ENSGALP00010012861.1" } ] } }, { "isoform_ac": "A0A8V0XX64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX64/entry", "sequence": { "sequence": "MGSGSSEKKEGSSCRITAENCCRYVWRRRERGLSCGANSSTSPESLGCSKITITTCLLQVSPVAMERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 539, "header": "tr|A0A8V0XX64-1|RHG15_CHICK Computationally mapped isoform of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638247, "end_pos": 32326617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022365.1", "url": "https://www.ensembl.org/id/ENSGALT00010022365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012866.1", "url": "https://www.ensembl.org/id/ENSGALP00010012866.1" } ] } }, { "isoform_ac": "A0A8V0Y5R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5R4/entry", "sequence": { "sequence": "MERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKNIANHQTRLPRATSSLALNASRDGASTTSLGKLFQCVTAFWDSSQGIRESYVNTKLRNCVWTNTP", "length": 479, "header": "tr|A0A8V0Y5R4-1|RHG15_CHICK Computationally mapped isoform of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638138, "end_pos": 32335698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022373.1", "url": "https://www.ensembl.org/id/ENSGALT00010022373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012874.1", "url": "https://www.ensembl.org/id/ENSGALP00010012874.1" } ] } }, { "isoform_ac": "A0A8V0YA87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA87/entry", "sequence": { "sequence": "MERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 442, "header": "tr|A0A8V0YA87-1|RHG15_CHICK Computationally mapped isoform of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638247, "end_pos": 32335698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022377.1", "url": "https://www.ensembl.org/id/ENSGALT00010022377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012878.1", "url": "https://www.ensembl.org/id/ENSGALP00010012878.1" } ] } }, { "isoform_ac": "Q5ZMM3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3/entry#Q5ZMM3-1", "sequence": { "sequence": "MERSTTSDTASEKPNPSHSTGAVQMRIKNANSHHDRLSQSKSMILSDNVKVLEPINRHRRNHSQHNLTLADIISTPDHTVVEKEGYLLKAKIADGGKKLRKNWSTSWIVLTSRKMEFYKESKQPALANLKPGYKPECVDLCGAHIEWTPEKSSRKNVFQITTVSGNEFLLQSDIDFLILDWFHAIKNAIDRLPKERSCTSRNLEFKLRRSSSTELLNSLDTESKESKPEHRKSLIFRLNYSASDSNDRSRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHLVCEHENSTVPQFVRQCIKAVERRGLEVDGIYRVSGNLATIQKLRFVVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYCFFEQFVEAIKIQDNATRIKAVKTLVKKLPRPNYDTMKVLFEHLKKIAAKESVNLMSTQSLGIVFGPTLLRPEKETGNMAVHMLYQNQIVELMLSEYSKIFGSEED", "length": 475, "header": "sp|Q5ZMM3-1|RHG15_CHICK Isoform 1 of Rho GTPase-activating protein 15 OS=Gallus gallus OX=9031 GN=ARHGAP15 PE=2 SV=1 CANONICAL=Q5ZMM3-1" }, "locus": { "chromosome": "7", "start_pos": 32638247, "end_pos": 32335698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022374.1", "url": "https://www.ensembl.org/id/ENSGALT00010022374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012875.1", "url": "https://www.ensembl.org/id/ENSGALP00010012875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424303", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A4IF90-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "ARHGAP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQKSTNSDIPVETLNPTRQGTGAVQMRIKNANSHHDRLSQSKSMILTEVGKVTEPISRHRRNHSQHILKDVIPPLEQLMVEKEGYLQKAKIADGGKKLRKNWTTSWIVLSSRKIEFYKESKQQALSNMKTGNKPESVDLCGAHIEWAKEKSSRKNVFQITTLSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDPSSHSRNLELFKIQRSSSTELLSHYDSDTKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHTLCEREKSTVPRFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRDLPEPLFPYSFFEQFVEAIKKQDNNTRIEAIKSLVQKLPPPNRDTMKVLFGHLTKIVARASKNLMSTHSLGIVFGPTLLRAEDESGNMAVHMVYQNQIAELMLSAYDQIFS", "length": 471 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0S8J8-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "arhgap15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQKPPALVLPGAVQLRIKNSQSSTGERLSQTKSMVLPEAETLQKPINRHRRNQSQHNSEVSVGLQPVLKGEYLNKAKIAEGGKKLRKNWTLTWVVLSSNQLLFYKESKQEAVSNLKPGGKPDGVDLNGAVIEWTTEKSSRKNVIQITTPTGHEFLLQADHFPTISKWHDAIKKAVDILSSGSGGQSCGRAALHRSNSTECLSRPTCESSKPKPKETKSEHRRSIMFKLNYSASDSADKNGVKNRLKKFISRRPSMKTLQEKGIIKDRVFGCHMLTLCDREKTTVPKFVKLCVEEVEKRGLEADGIYRVSGNLAIIQKLRFLVDQEEELDLGDSQWEDIHVITGALKMFFRELPEPLFPFRFFDLFVETIKIKEPTQKVQAMKKLIHQLPKPNHNTMKLLFHHLRRVLTKSQKNLMSTQGVSIVFGPTLMWPEFESGNMEVNMVYQNQIVECILIGCVEIFGPADK", "length": 465 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LUA7-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "ARHGAP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKSTNSDTSVETLNPTRQATGAVQMRIKNANSHHDRLSQSKSMILTDVGKVTEPISRHRRNHSQHILKDVIPPLEQLMVEKEGYLQKAKIADGGKKLRKNWSTSWVVLSSRKIEFYKESKQQALSNMKTGHKPENIDLCGAQIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDPSTPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHTVCERENSTVPRFVKQCIEAVEKRGLNVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFERFVEAIKKQDNNTRIETVKSLVQKLPPPNRDTMKVLFRHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENEAGNMAVHMVYQNQIVELMLSEYSKIFGLEED", "length": 475 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q53QZ3-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "ARHGAP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKSTNSDTSVETLNSTRQGTGAVQMRIKNANSHHDRLSQSKSMILTDVGKVTEPISRHRRNHSQHILKDVIPPLEQLMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNMKTGHKPESVDLCGAHIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED", "length": 475 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AYC5-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "Arhgap15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKRTSCSVQTSTNCDNSLETLNSAHQATGAVQMRIKNANSHPDRQSQTKSMILTDAGKVTEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGRKLEFYKDPKQQALPNVKPRPNAESVDLCGAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFGSLELFSFQRSSSSEQPSHCHIDRKEQKPENRKSFMFRLHHSVSDTSDKNRVKSRLKKFISRRPSLKTLQEKGIIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLEVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSDAKIETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQVAEFMLTEYDKIFSSEED", "length": 482 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q811M1-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "Arhgap15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRTSCSVQTSTNCDNSLEILNSAHQATGAVQMRIKNANSHQDRQSQTKSMILTDAGKVTEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGRKIEFYKDSKQQALPNMKTRHNVESVDLCGAHIEWAKEKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGSLELFNLQRSSSSELPSHCHIDRKEQKPEHRKSFMFRLHHSASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKIETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEED", "length": 481 }, "evidence": [ { "id": "Q5ZMM3", "url": "https://omabrowser.org/oma/group/Q5ZMM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 475, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMM3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 80, "end_pos": 190, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM3" }, { "id": "PRU00172", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00172" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000255", "start_pos": 281, "end_pos": 470, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLL0-1", "uniprot_ac": "Q5ZLL0", "uniprot_id": "VMA21_CHICK", "mass": { "chemical_mass": 11578.0, "monoisotopic_mass": 11578.0 }, "refseq": { "ac": "NP_001026298", "name": "vacuolar ATPase assembly integral membrane protein VMA21", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298" }, "gene_names": [ { "name": "VMA21", "type": "recommended", "evidence": [ { "id": "Q5ZLL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ] }, { "name": "RCJMB04_5k12", "type": "synonym", "evidence": [ { "id": "Q5ZLL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ] }, { "name": "VMA21", "type": "synonym", "evidence": [ { "id": "NP_001026298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298" } ] } ], "protein_names": [ { "name": "Vacuolar ATPase assembly integral membrane protein VMA21", "type": "recommended", "evidence": [ { "id": "Q5ZLL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0/entry#names_and_taxonomy" } ] }, { "name": "VMA21, vacuolar ATPase assembly factor", "type": "synonym", "evidence": [ { "id": "NP_001026298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298" } ] }, { "name": "vacuolar ATPase assembly integral membrane protein VMA21", "type": "synonym", "evidence": [ { "id": "NP_001026298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.2736.1, HAEK01018907.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Aug 8, 2005 this sequence version replaced XP_420354.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298" } ] }, { "annotation": "Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y942", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y942#function" }, { "database": "HAMAP", "id": "MF_03058", "url": "https://hamap.expasy.org/signature/MF_03058" }, { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0#function" }, { "database": "UniProtKB", "id": "Q78T54", "url": "https://www.uniprot.org/uniprotkb/Q78T54#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VMA21", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0", "locus": { "chromosome": "4", "start_pos": 17457878, "end_pos": 17463950, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011372", "url": "https://www.ensembl.org/id/ENSGALG00010011372" } ] } } ], "crossref": [ { "id": "Q5ZLL0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "422385", "url": "https://www.ncbi.nlm.nih.gov/gene/422385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422385", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422385", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYFRGNE", "url": "https://omabrowser.org/oma/group/PYFRGNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y942", "url": "https://www.orthodb.org/?gene=A0A8V0Y942", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLL0", "url": "https://www.orthodb.org/?gene=Q5ZLL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31792:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31792:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09446", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09446", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLL0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLL0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y942", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y942", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y942-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y942-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLL0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERYDKATLNAAFAPEFRQNEGSLTSTLRTLLFFTALMITLPVGLYFSSKAYIFEGTLGMSNRDSYFYAAIVAVVTVHVVLAMFVYVAWSEGTRQWREGKQD", "length": 102, "header": "sp|Q5ZLL0-1|VMA21_CHICK Isoform 1 of Vacuolar ATPase assembly integral membrane protein VMA21 OS=Gallus gallus OX=9031 GN=VMA21 PE=3 SV=1 CANONICAL=Q5ZLL0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y942-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y942/entry", "sequence": { "sequence": "MERYDKATLNAAFAPEFRQNEGSLTSTLRTLLFFTALMITLPVGLYFSSKAYIFEGMSNRDSYFYAAIVAVVTVHVVLAMFVYVAWSEGTRQWREGKQD", "length": 99, "header": "tr|A0A8V0Y942-1|VMA21_CHICK Computationally mapped isoform of Vacuolar ATPase assembly integral membrane protein VMA21 OS=Gallus gallus OX=9031 GN=VMA21 PE=3 SV=1 CANONICAL=Q5ZLL0-1" }, "locus": { "chromosome": "4", "start_pos": 17463897, "end_pos": 17460723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027203.1", "url": "https://www.ensembl.org/id/ENSGALT00010027203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015492.1", "url": "https://www.ensembl.org/id/ENSGALP00010015492.1" } ] } }, { "isoform_ac": "Q5ZLL0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0/entry#Q5ZLL0-1", "sequence": { "sequence": "MERYDKATLNAAFAPEFRQNEGSLTSTLRTLLFFTALMITLPVGLYFSSKAYIFEGTLGMSNRDSYFYAAIVAVVTVHVVLAMFVYVAWSEGTRQWREGKQD", "length": 102, "header": "sp|Q5ZLL0-1|VMA21_CHICK Isoform 1 of Vacuolar ATPase assembly integral membrane protein VMA21 OS=Gallus gallus OX=9031 GN=VMA21 PE=3 SV=1 CANONICAL=Q5ZLL0-1" }, "locus": { "chromosome": "4", "start_pos": 17463897, "end_pos": 17460723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027201.1", "url": "https://www.ensembl.org/id/ENSGALT00010027201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015490.1", "url": "https://www.ensembl.org/id/ENSGALP00010015490.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422385", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422385", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2VDK9-1", "protein_name": "Vacuolar ATPase assembly integral membrane protein VMA21", "gene_name": "VMA21", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERLDKAALNALQPSDFRNESSLASTLKTLLFFTALMITVPIGLYFTTKSYVFEGAFGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD", "length": 101 }, "evidence": [ { "id": "Q5ZLL0", "url": "https://omabrowser.org/oma/group/Q5ZLL0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZM03-1", "protein_name": "Vacuolar ATPase assembly factor VMA21", "gene_name": "Vma21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERLDKAALNALQPPEFRNENSLAATLKTLLFFTALMITVPIGLYFTTKSYIFEGALGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD", "length": 101 }, "evidence": [ { "id": "Q5ZLL0", "url": "https://omabrowser.org/oma/group/Q5ZLL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I4B1-1", "protein_name": "Vacuolar ATPase assembly integral membrane protein VMA21", "gene_name": "Vma21", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERLDKAALNAMQPPEFRNENSLASTLKTLLFFTALMITVPIGLYFTTKSYVFEGALGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD", "length": 101 }, "evidence": [ { "id": "Q5ZLL0", "url": "https://omabrowser.org/oma/group/Q5ZLL0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZAQ7-1", "protein_name": "Vacuolar ATPase assembly integral membrane protein VMA21", "gene_name": "VMA21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERPDKAALNALQPPEFRNESSLASTLKTLLFFTALMITVPIGLYFTTKSYIFEGALGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD", "length": 101 }, "evidence": [ { "id": "Q5ZLL0", "url": "https://omabrowser.org/oma/group/Q5ZLL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q78T54-1", "protein_name": "Vacuolar ATPase assembly integral membrane protein Vma21", "gene_name": "Vma21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERLDKAALNALQPPEFRNENSLAATLKTLLFFTALMITVPIGLYFTTKAYIFEGALGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD", "length": 101 }, "evidence": [ { "id": "Q5ZLL0", "url": "https://omabrowser.org/oma/group/Q5ZLL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vacuolar proton-transporting V-type ATPase complex assembly", "id": "GO:0070072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070072", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" }, { "name": "lysosomal lumen acidification", "id": "GO:0007042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007042", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLL0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 102, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLL0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLL0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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3 subunit L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" }, "gene_names": [ { "name": "EIF3L", "type": "recommended", "evidence": [ { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ] }, { "name": "EIF3EIP", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" }, { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ] }, { "name": "EIF3L", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" } ] }, { "name": "EIF3S6IP", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" }, { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ] }, { "name": "RCJMB04_3l6", "type": "synonym", "evidence": [ { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 3 subunit L", "type": "recommended", "evidence": [ { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428/entry#names_and_taxonomy" } ] }, { "name": "eIF3l", "type": "synonym", "evidence": [ { "id": "Q5F428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F428/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 3 subunit L", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" } ] }, { "name": "eukaryotic translation initiation factor 3, subunit 6 interacting protein", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" } ] }, { "name": "eukaryotic translation initiation factor 3, subunit E interacting protein", "type": "synonym", "evidence": [ { "id": "NP_001012553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851472.1, HAEL01000021.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Feb 28, 2005 this sequence version replaced XP_416270.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553" } ] }, { "annotation": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L1#function" }, { "database": "HAMAP", "id": "MF_03011", "url": "https://hamap.expasy.org/signature/MF_03011" }, { "database": "UniProtKB", "id": "A0A8V0Y9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L6#function" }, { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF3L", "url": "https://www.uniprot.org/uniprotkb/Q5F428", "locus": { "chromosome": "1", "start_pos": 51136941, "end_pos": 51146623, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010593", "url": "https://www.ensembl.org/id/ENSGALG00010010593" } ] } } ], "crossref": [ { "id": "Q5F428", "url": "https://alphafold.ebi.ac.uk/entry/Q5F428", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012296", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418033", "url": "https://www.ncbi.nlm.nih.gov/gene/418033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418033", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AGWFIRN", "url": "https://omabrowser.org/oma/group/AGWFIRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9L1", "url": "https://www.orthodb.org/?gene=A0A8V0Y9L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9L6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5F428", "url": "https://www.orthodb.org/?gene=Q5F428", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13242:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13242:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F428", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F428", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F428-1", "url": "https://www.uniprot.org/uniprotkb/Q5F428-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYPGEDYDNDAAYDPYAYSNDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPTLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDAQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFADEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564, "header": "sp|Q5F428-1|EIF3L_CHICK Isoform 1 of Eukaryotic translation initiation factor 3 subunit L OS=Gallus gallus OX=9031 GN=EIF3L PE=2 SV=1 CANONICAL=Q5F428-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L1/entry", "sequence": { "sequence": "MAYPGEDYDNDAAYDPYAYSNDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNGKCFFSTLFSYQRMKELNHFRRITEPGGPTLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDAQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFADEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 569, "header": "tr|A0A8V0Y9L1-1|EIF3L_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Gallus gallus OX=9031 GN=EIF3L PE=2 SV=1 CANONICAL=Q5F428-1" }, "locus": { "chromosome": "1", "start_pos": 51146530, "end_pos": 51137161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025220.1", "url": "https://www.ensembl.org/id/ENSGALT00010025220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014292.1", "url": "https://www.ensembl.org/id/ENSGALP00010014292.1" } ] } }, { "isoform_ac": "A0A8V0Y9L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9L6/entry", "sequence": { "sequence": "MAYPGEDYDNDAAYDPYAYSNDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPTLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDAQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFADEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 547, "header": "tr|A0A8V0Y9L6-1|EIF3L_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 3 subunit L OS=Gallus gallus OX=9031 GN=EIF3L PE=2 SV=1 CANONICAL=Q5F428-1" }, "locus": { "chromosome": "1", "start_pos": 51146530, "end_pos": 51137161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025230.1", "url": "https://www.ensembl.org/id/ENSGALT00010025230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014298.1", "url": "https://www.ensembl.org/id/ENSGALP00010014298.1" } ] } }, { "isoform_ac": "Q5F428-1", "url": "https://www.uniprot.org/uniprotkb/Q5F428/entry#Q5F428-1", "sequence": { "sequence": "MAYPGEDYDNDAAYDPYAYSNDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPTLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDAQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFADEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564, "header": "sp|Q5F428-1|EIF3L_CHICK Isoform 1 of Eukaryotic translation initiation factor 3 subunit L OS=Gallus gallus OX=9031 GN=EIF3L PE=2 SV=1 CANONICAL=Q5F428-1" }, "locus": { "chromosome": "1", "start_pos": 51146530, "end_pos": 51137161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025223.1", "url": "https://www.ensembl.org/id/ENSGALT00010025223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014295.1", "url": "https://www.ensembl.org/id/ENSGALP00010014295.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418033", "resource": "KEGG Pathway" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MQ91-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "Eif3l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYPADDYESEAAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F4JY76-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASSNEYEEGPGERESGYDPNMVPDSVKSFVSHMYRHIRDKNVYEIHQMCETSFQSISERLFKDTPWPSVEAIAPYVDNDHVFCLLYREMWFRHLYARLSPTLKQRIDSYDNYCSLFQVVLHGVVNMQLPNQWLWDMVDEFVYQFQSFCQFRAKLKNKTEEEIALLRQHDKAWNVYGVLNFLQALVEKSCIIQILEHDKDGLEFTETDGYDFSGGSNVLKVLGYFSMVGLLRVHCLLGDYHTALKWLQPIDITQPGVYTSVIGCHIATIYHYGFATLMLRRYVDAVREFNKILLYIFKTKQYHQKSPQYEQLLKKNEQMYALLALSLSLCPQTKLVDESVNSQLRDKYGEKMMRMLRSDDEAFGIYDELFSYACPKFITPSAPPTFEEPLVNYNQDAYRLQLKMFLYEVKQQQLLSGVRTFLKVYSSISLAKLANYMEVDEPTLRTILLTYKHKTHSVDSDGRIISNADIDFFINNDMIYVVESKPAKRYGDFFLRQIAKLEGVINDMDRVKLE", "length": 514 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3V7G9-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "Eif3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYPADDYESETAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ZCK1-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "EIF3L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYPADDYESEAAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAETIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7T2A5-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "eif3l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYPAEEEDVNYDPYSYPNDYDYHTGDPKADLAYERQYEHQQTYHVIPEVIKNFLQYFHKTISDLIDQKVYELQANRVSSESIEQKIYEIQDVYENSWNKLTDRFFKTSPWPEAEAIASLVGNDAVFLILYKELYYRHIYAKVSGGPTLDQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIEFLRNNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQITTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTRNMFQRTTYKYEMINKQNEQMHGLLAIALTMYPMRIDESIHTQLREKYGDKMLRMQKGDLQVFEELFSFACPKFLSPVVPNYENVHPNYHKEPFQQQLKVFAEEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDMSEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMPLNTGASISSSSTSRAT", "length": 576 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86LA2-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "eif3L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQTNNAGTTNTNTNQNNNRKGGNNKNYQNRNNNNQQQQGGQQQQQQQHRNKHQNQQGNQNQQGNQQGGGNQQQNKQGGHRGGKTPSNVESFPINLSQQQVQQLQAYQQQTQQNQSAQFQSNFLPPATALYTPVINYFINLYNNFKSQSHQDILVSYDSFFKSCETYYPHCALPTIENLIPILGDKFEESSFTDRFFVLLYKEIYYRYYYALVFQPNINTCVESWQNYYQIFHTLLSANSPNDVEIDLPNAWLWDLVDEFVYQYHTFAKFKLKKQDVDFLSENPEIWDTTNVIRYLYYIIKKSQIFSANTNRFESSSEDFCSHPVYKMLGYYSVISLVRVQCLLGDYTLALKTLELIDMGKKAMYTYVTACHITLYYYLGFAYLMSRKYNEATKALNTILVSVASKSKSQNFQSDHNEKKTDKMYALLTICQALYPNKIDENVSNNLKEKFGDKLLRLQKGDLSVYEELYTFAAPRCIGPVPPYISGFNVTALDPHRLQLSLFLEEVKQQSLLTTIRSYITLYSTISIQKLAGLLQIDPEDLRVKLTCYKHKLFNVLGKGETKWNNQLDIDFYIDQDMIHIDNRLYAKETDSFINSILKFEGSLTPSYNWM", "length": 611 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8QZY1-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "Eif3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYPADDYESEAAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEGEMDFLRSNPKVWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTU4-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "eIF3l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYGGDEYATNSDYYDDYAHTGDPQLDMEYERNYYAARMPDNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWSILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNINI", "length": 539 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y262-1", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "EIF3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYPADDYESEAAYDPYAYPSDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP", "length": 564 }, "evidence": [ { "id": "Q5F428", "url": "https://omabrowser.org/oma/group/Q5F428/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "pmid": "" }, { "name": "viral translational termination-reinitiation", "id": "GO:0075525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075525", "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q5F428", "url": "https://www.uniprot.org/uniprotkb/Q5F428" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U6Y4-1", "uniprot_ac": "A0A3Q2U6Y4", "uniprot_id": "A0A3Q2U6Y4_CHICK", "mass": { "chemical_mass": 79323.0, "monoisotopic_mass": 79323.0 }, "refseq": { "ac": "XP_003641480", "name": "pre-mRNA-processing factor 39 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641480" }, "gene_names": [ { "name": "FAM179B", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4" } ] }, { "name": "FAM179B", "type": "synonym", "evidence": [ { "id": "XP_003641480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641480" } ] } ], "protein_names": [ { "name": "Pre-mRNA-processing factor 39", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4/entry#names_and_taxonomy" } ] }, { "name": "PRP39 homolog", "type": 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641480" } ] }, { "annotation": "Involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4#function" }, { "database": "UniProtKB", "id": "ARBA00003777", "url": "https://www.uniprot.org/uniprotkb/ARBA00003777#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM179B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4", "locus": {} } ], "crossref": [ { 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factor 39 OS=Gallus gallus OX=9031 GN=FAM179B PE=1 SV=1 CANONICAL=A0A3Q2U6Y4-1" }, "locus": { "chromosome": "5", "start_pos": 58577275, "end_pos": 58564081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044193.1", "url": "https://www.ensembl.org/id/ENSGALT00010044193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026284.1", "url": "https://www.ensembl.org/id/ENSGALP00010026284.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858094", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6Y4", "url": 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"A0A3Q2U6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U6Y4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 680, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U6Y4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6Y4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 622, "end_pos": 624 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLD3-1", "uniprot_ac": "Q5ZLD3", "uniprot_id": "KLH13_CHICK", "mass": { "chemical_mass": 70970.0, "monoisotopic_mass": 70970.0 }, "refseq": { "ac": "NP_001026287", "name": "kelch-like protein 13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" }, "gene_names": [ { "name": "KLHL13", "type": "recommended", "evidence": [ { "id": "Q5ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ] }, { "name": "KLHL9", "type": "recommended", "evidence": [ { "id": "Q5ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ] }, { "name": "KLHL13", "type": "synonym", "evidence": [ { "id": "NP_001026287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" } ] }, { "name": "KLHL9", "type": "synonym", "evidence": [ { "id": "NP_001026287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" } ] }, { "name": "RCJMB04_6k12", "type": "synonym", "evidence": [ { "id": "Q5ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ] } ], "protein_names": [ { "name": "Kelch-like protein 13", "type": "recommended", "evidence": [ { "id": "Q5ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 13", "type": "synonym", "evidence": [ { "id": "NP_001026287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" } ] }, { "name": "kelch-like protein 13", "type": "synonym", "evidence": [ { "id": "NP_001026287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719801.1, SRR13267659.16753.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Aug 8, 2005 this sequence version replaced XP_420214.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287" } ] }, { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3#function" }, { "database": "UniProtKB", "id": "A0A1D5P647", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P647#function" }, { "database": "UniProtKB", "id": "ARBA00056604", "url": "https://www.uniprot.org/uniprotkb/ARBA00056604#function" }, { "database": "UniProtKB", "id": "A0A8V0YP37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP37#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL13", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3", "locus": {} } ], "crossref": [ { "id": "Q5ZLD3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005982", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005982", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18449", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18449", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422226", "url": "https://www.ncbi.nlm.nih.gov/gene/422226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422226", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422226", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P647", "url": "https://www.orthodb.org/?gene=A0A1D5P647", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP37", "url": "https://www.orthodb.org/?gene=A0A8V0YP37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLD3", "url": "https://www.orthodb.org/?gene=Q5ZLD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLD3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLD3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P647", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P647", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P647-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P647-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLD3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMWRDALSLVEEEDPHMKVSLGSSDMGVSAHLQSSKTGTTRFFTSNTHSSVVLQGFDQLRVEGLLCDVTLVPGDGDEVFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKIGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLENCVEVGRIANTYNLTEVDKYVNNFILKNFPALLSTGEFVKLPFERLAFVLSSNSLKHCTELELFKAACRWLRFEEPRMEYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRMNEWSYVAKMNEPHYGHAGTVYGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSTTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDNTGSPSRESPLSAP", "length": 629, "header": "sp|Q5ZLD3-1|KLH13_CHICK Isoform 1 of Kelch-like protein 13 OS=Gallus gallus OX=9031 GN=KLHL13 PE=2 SV=1 CANONICAL=Q5ZLD3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P647-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P647/entry", "sequence": { "sequence": "MLRFISHLYCCSSKEECSEDDKCILSRSLVEEEDPHMKVSLGSSDMGVSAHLQSSKTGTTRFFTSNTHSSVVLQGFDQLRVEGLLCDVTLVPGDGDEVFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKIGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLENCVEVGRIANTYNLTEVDKYVNNFILKNFPALLSTGEFVKLPFERLAFVLSSNSLKHCTELELFKAACRWLRFEEPRMEYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRMNEWSYVAKMNEPHYGHAGTVYGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSTTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDNTGSPSRESPLSAP", "length": 649, "header": "tr|A0A1D5P647-1|KLH13_CHICK Computationally mapped isoform of Kelch-like protein 13 OS=Gallus gallus OX=9031 GN=KLHL13 PE=2 SV=2 CANONICAL=Q5ZLD3-1" }, "locus": { "chromosome": "4", "start_pos": 3185451, "end_pos": 3155558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034819.1", "url": "https://www.ensembl.org/id/ENSGALT00010034819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020402.1", "url": "https://www.ensembl.org/id/ENSGALP00010020402.1" } ] } }, { "isoform_ac": "A0A8V0YP37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP37/entry", "sequence": { "sequence": "MDTCVPGCLPTSPGNASKEECSEDDKCILSRSLVEEEDPHMKVSLGSSDMGVSAHLQSSKTGTTRFFTSNTHSSVVLQGFDQLRVEGLLCDVTLVPGDGDEVFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKIGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLENCVEVGRIANTYNLTEVDKYVNNFILKNFPALLSTGEFVKLPFERLAFVLSSNSLKHCTELELFKAACRWLRFEEPRMEYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRMNEWSYVAKMNEPHYGHAGTVYGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSTTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDNTGSPSRESPLSAP", "length": 653, "header": "tr|A0A8V0YP37-1|KLH13_CHICK Computationally mapped isoform of Kelch-like protein 13 OS=Gallus gallus OX=9031 GN=KLHL13 PE=2 SV=1 CANONICAL=Q5ZLD3-1" }, "locus": { "chromosome": "4", "start_pos": 3185911, "end_pos": 3155558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034823.1", "url": "https://www.ensembl.org/id/ENSGALT00010034823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020403.1", "url": "https://www.ensembl.org/id/ENSGALP00010020403.1" } ] } }, { "isoform_ac": "Q5ZLD3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3/entry#Q5ZLD3-1", "sequence": { "sequence": "MMWRDALSLVEEEDPHMKVSLGSSDMGVSAHLQSSKTGTTRFFTSNTHSSVVLQGFDQLRVEGLLCDVTLVPGDGDEVFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKIGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLENCVEVGRIANTYNLTEVDKYVNNFILKNFPALLSTGEFVKLPFERLAFVLSSNSLKHCTELELFKAACRWLRFEEPRMEYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRMNEWSYVAKMNEPHYGHAGTVYGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSTTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDNTGSPSRESPLSAP", "length": 629, "header": "sp|Q5ZLD3-1|KLH13_CHICK Isoform 1 of Kelch-like protein 13 OS=Gallus gallus OX=9031 GN=KLHL13 PE=2 SV=1 CANONICAL=Q5ZLD3-1" }, "locus": { "chromosome": "4", "start_pos": 3207003, "end_pos": 3155558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034829.1", "url": "https://www.ensembl.org/id/ENSGALT00010034829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020405.1", "url": "https://www.ensembl.org/id/ENSGALP00010020405.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422226", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 629, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD3" }, { "id": "PRU00037", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000255", "start_pos": 66, "end_pos": 135, "start_aa": "Cys", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q5F476-1", "uniprot_ac": "Q5F476", "uniprot_id": "CDIN1_CHICK", "mass": { "chemical_mass": 31423.0, "monoisotopic_mass": 31423.0 }, "refseq": { "ac": "NP_001026371", "name": "CDAN1-interacting nuclease 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" }, "gene_names": [ { "name": "CDIN1", "type": "recommended", "evidence": [ { "id": "Q5F476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ] }, { "name": "C15orf41", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "name": "C5H15orf41", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "name": "CDIN1", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "name": "RCJMB04_2g23", "type": "synonym", "evidence": [ { "id": "Q5F476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ] } ], "protein_names": [ { "name": "CDAN1-interacting nuclease 1", "type": "recommended", "evidence": [ { "id": "Q5F476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F476/entry#names_and_taxonomy" } ] }, { "name": "CDAN1-interacting nuclease 1", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "name": "chromosome 5 C15orf41 homolog", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "name": "uncharacterized protein C15orf41 homolog", "type": "synonym", "evidence": [ { "id": "NP_001026371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851424.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Aug 8, 2005 this sequence version replaced XP_421213.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026371", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371" } ] }, { "annotation": "May play a role in erythroid cell differentiation.", "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476#function" }, { "database": "UniProtKB", "id": "Q9Y2V0", "url": "https://www.uniprot.org/uniprotkb/Q9Y2V0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDIN1", "url": "https://www.uniprot.org/uniprotkb/Q5F476", "locus": { "chromosome": "5", "start_pos": 30936355, "end_pos": 31051965, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005372", "url": "https://www.ensembl.org/id/ENSGALG00010005372" } ] } } ], "crossref": [ { "id": "Q5F476", "url": "https://alphafold.ebi.ac.uk/entry/Q5F476", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009801", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423293", "url": "https://www.ncbi.nlm.nih.gov/gene/423293", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423293", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423293", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYWNRFG", "url": "https://omabrowser.org/oma/group/CYWNRFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB74", "url": "https://www.orthodb.org/?gene=A0A1D5PB74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5F476", "url": "https://www.orthodb.org/?gene=Q5F476", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31661:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31661:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F476", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F476", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026371", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026371", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PB74", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB74-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F476-1", "url": "https://www.uniprot.org/uniprotkb/Q5F476-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLTKAQYDEIAQFLGHVQPTRQSLRKLKEKFPSQSQSTLLSIFSQEYQKQIKRTHAKHHTAEAVETYYQRYLNGVMKNAAAPVLLELANEMDFAPSLMARIVLERFLQEQEQAIPSKTLINSMLRDPSQIPDGVLANQIYQCTVNDCCYGPLVDCIKHFINNRSCSLCVAEDQLRAKGYDKTPDFILEVPVAVEGHIIHWIESKASFGDESSHQAYLQDQFWSYWNRFGPGLVIYWYGFIEELDCHRERGILLKDCFPTDIVTLRHSMAQR", "length": 272, "header": "sp|Q5F476-1|CDIN1_CHICK Isoform 1 of CDAN1-interacting nuclease 1 OS=Gallus gallus OX=9031 GN=CDIN1 PE=2 SV=1 CANONICAL=Q5F476-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB74-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB74/entry", "sequence": { "sequence": "MKLTKAQYDEIAQFLGHVQPTRQSLRKLKEKFPSQSQSTLLSIFSQEYQKQIKRTHAKHHTAEAVETYYQRYLNGVMKNAAAPVLLELANEMDFAPSLMARIVLERFLQEQEQAIPSKTLINSMLRDPSQIPDGVLANQIYQCTVNDCCYGPLVDCIKHAIGHEHEVLLREMLLEKNLSFIAEDQLRAKGYDKTPDFILEVPVAVEGHIIHWIESKASFGDESSHQAYLQDQFWSYWNRFGPGLVIYWYGFIEELDCHRERGILLKDCFPTDIVTLRHSMAQR", "length": 283, "header": "tr|A0A1D5PB74-1|CDIN1_CHICK Computationally mapped isoform of CDAN1-interacting nuclease 1 OS=Gallus gallus OX=9031 GN=CDIN1 PE=2 SV=1 CANONICAL=Q5F476-1" }, "locus": { "chromosome": "5", "start_pos": 31051678, "end_pos": 30939661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012780.1", "url": "https://www.ensembl.org/id/ENSGALT00010012780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007343.1", "url": "https://www.ensembl.org/id/ENSGALP00010007343.1" } ] } }, { "isoform_ac": "Q5F476-1", "url": "https://www.uniprot.org/uniprotkb/Q5F476/entry#Q5F476-1", "sequence": { "sequence": "MKLTKAQYDEIAQFLGHVQPTRQSLRKLKEKFPSQSQSTLLSIFSQEYQKQIKRTHAKHHTAEAVETYYQRYLNGVMKNAAAPVLLELANEMDFAPSLMARIVLERFLQEQEQAIPSKTLINSMLRDPSQIPDGVLANQIYQCTVNDCCYGPLVDCIKHFINNRSCSLCVAEDQLRAKGYDKTPDFILEVPVAVEGHIIHWIESKASFGDESSHQAYLQDQFWSYWNRFGPGLVIYWYGFIEELDCHRERGILLKDCFPTDIVTLRHSMAQR", "length": 272, "header": "sp|Q5F476-1|CDIN1_CHICK Isoform 1 of CDAN1-interacting nuclease 1 OS=Gallus gallus OX=9031 GN=CDIN1 PE=2 SV=1 CANONICAL=Q5F476-1" }, "locus": { "chromosome": "5", "start_pos": 31051678, "end_pos": 30939661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012772.1", "url": "https://www.ensembl.org/id/ENSGALT00010012772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007336.1", "url": "https://www.ensembl.org/id/ENSGALP00010007336.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423293", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423293", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JLZ3-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "Cdin1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILTKAQYEEIAQCLVSVPPTRQSLRKLKQRFPSSVHEHSNKWWLITQGKSQSQATLLSIFSQEYQKHIKRTHAKHHTPEAIESYYQRYLNGVGKNGAAPVLLELANEVDYAPSLMARIILERFLQGREQTPPSKSVINNMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGYEHEVLLRDLLLKKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHGQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKACFPTDIVTLCHSTA", "length": 298 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZYC4-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "Cdin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILTKAQYEEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTPEAIESYYQRYLSGVGKNGAAPVLLELANEVDYAPSLMARIILERFLQGHEQTPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGYEHEVLLRDLLLKKNLSFLDEDQLRAKGYDKTPDFILQVPVVMLCPLAVEGHIIHWIESKASFGDECSHHAYLHGQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKASFPTDIVTLCHSTA", "length": 287 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08BW6-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "cdin1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAVSGGSATGTGEQVNNLRICRAEYRSISRFVEQLRPTRQCMKTLQTHFTHLPASTLLSIFSQEYQKRMKRSMARHHSPEVLRVYYQRYRDEAETRATEPLLLELANQVDLSPALLARLMLECFLEERNASVPSRQVLNNMLREPYLIPDLVLAKHIEQCTVNDCCYGPLVDCIKHAIGLEHEDTLRDKLRERNLSFLDENQLRVKGYDKTPDIILEVPIAVDGHIVHWIESKASFGDDHSHNTYLNEQFWSYCNRFGPGLVIYWFGFISELDCQRERGILLKDGFPTDISSLCAGPQR", "length": 300 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U4G0-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "Cdin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILTKAQYEEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTPEAIESYYQRYLNGVGKNGAAPVLLELANEVDYAPSLMARIILERFLQGHEQTPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGYEHEVLLRDLLLKKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHGQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKASFPTDIVTLCHSTA", "length": 281 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5E9S8-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "CDIN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVRKNGAAPVLLELANEVDYAPSLMARIILERFLQKHEEAPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRARGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHDQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLHACFPTDIVTLCHSVA", "length": 281 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y2V0-1", "protein_name": "CDAN1-interacting nuclease 1", "gene_name": "CDIN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLANEVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHDQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKACFPTNIVTLCHSIA", "length": 281 }, "evidence": [ { "id": "Q5F476", "url": "https://omabrowser.org/oma/group/Q5F476/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "Q5F476", "url": "https://www.uniprot.org/uniprotkb/Q5F476" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F476-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 272, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F476-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F476" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJK0-1", "uniprot_ac": "Q5ZJK0", "uniprot_id": "RGPS1_CHICK", "mass": { "chemical_mass": 65153.0, "monoisotopic_mass": 65153.0 }, "refseq": { "ac": "NP_001006532", "name": "ras-specific guanine nucleotide-releasing factor RalGPS1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" }, "gene_names": [ { "name": "RALGPS1", "type": "recommended", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ] }, { "name": "RALGPS2", "type": "recommended", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ] }, { "name": "RALGPS1", "type": "synonym", "evidence": [ { "id": "NP_001006532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] }, { "name": "RALGPS2", "type": "synonym", "evidence": [ { "id": "NP_001006532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] }, { "name": "RCJMB04_17i24", "type": "synonym", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ] } ], "protein_names": [ { "name": "Ras-specific guanine nucleotide-releasing factor RalGPS1", "type": "recommended", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0/entry#names_and_taxonomy" } ] }, { "name": "Ral GEF with PH domain and SH3-binding motif 1", "type": "synonym", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0/entry#names_and_taxonomy" } ] }, { "name": "RalA exchange factor RalGPS1", "type": "synonym", "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0/entry#names_and_taxonomy" } ] }, { "name": "ral GEF with PH domain and SH3-binding motif 1", "type": "synonym", "evidence": [ { "id": "NP_001006532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] }, { "name": "ralA exchange factor RalGPS1", "type": "synonym", "evidence": [ { "id": "NP_001006532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] }, { "name": "ras-specific guanine nucleotide-releasing factor RalGPS1", "type": "synonym", "evidence": [ { "id": "NP_001006532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720434.1, SRR13267654.185423.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA103992290, SAMEA103992323 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000237.1. On Jan 13, 2005 this sequence version replaced XP_422272.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532" } ] }, { "annotation": "Guanine nucleotide exchange factor. May be involved in cytoskeletal organization.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RALGPS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0", "locus": { "chromosome": "17", "start_pos": 10969020, "end_pos": 10883511, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028692", "url": "https://www.ensembl.org/id/ENSGALG00010028692" } ] } } ], "crossref": [ { "id": "Q5ZJK0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004273", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004273", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13310", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13310", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424429", "url": "https://www.ncbi.nlm.nih.gov/gene/424429", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424429", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424429", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XSAESED", "url": "https://omabrowser.org/oma/group/XSAESED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PCW2", "url": "https://www.orthodb.org/?gene=A0A1D5PCW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3U8", "url": "https://www.orthodb.org/?gene=A0A8V0Y3U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA46", "url": "https://www.orthodb.org/?gene=A0A8V0YA46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJK0", "url": "https://www.orthodb.org/?gene=Q5ZJK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJK0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJK0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PCW2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJK0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLMNGQSSSVNIAATASEKSSSSESLSDKGSAELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPEELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILESEQRTNLMNNILRIISDLQQSCEYDIPLLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPHSAASREDLVASEVGASPQSGRKNAAAEGALLPPTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHVPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPGTRVSRNGYRGHMKASSSLESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWVALCGTQLFYYAAKSLKATERKHFKSTPSKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNRQQVPANLMTFE", "length": 584, "header": "sp|Q5ZJK0-1|RGPS1_CHICK Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=2 SV=1 CANONICAL=Q5ZJK0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCW2/entry", "sequence": { "sequence": "MDLMNGQSSSVNIAATASEKSSSSESLSDKGSAELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPEELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILESEQRTNLMNNILRIISDLQQSCEYDIPLLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPHSAASREDLVASEVGASPQSGRKNAAAEGALLPPTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHVPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFESSLESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWVALCGTQLFYYAAKSLKATERKHFKSTPSKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNRQQVPANLMTFE", "length": 558, "header": "tr|A0A1D5PCW2-1|RGPS1_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=2 SV=2 CANONICAL=Q5ZJK0-1" }, "locus": { "chromosome": "8", "start_pos": 6390043, "end_pos": 6305126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026846.1", "url": "https://www.ensembl.org/id/ENSGALT00010026846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015299.1", "url": "https://www.ensembl.org/id/ENSGALP00010015299.1" } ] } }, { "isoform_ac": "A0A8V0Y3U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3U8/entry", "sequence": { "sequence": "MGKKKSSSSESLSDKGSAELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPEELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILESEQRTNLMNNILRIISDLQQSCEYDIPLLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPHSAASREDLVASEVGASPQSGRKNAAAEGALLPPTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHVPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPGTRVSRNGYRGHMKASSSLESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWVALCGTQLFYYAAKSLKATERKHFKSTPSKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNRQQVPANLMTFE", "length": 569, "header": "tr|A0A8V0Y3U8-1|RGPS1_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=2 SV=1 CANONICAL=Q5ZJK0-1" }, "locus": { "chromosome": "8", "start_pos": 6387530, "end_pos": 6305126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026841.1", "url": "https://www.ensembl.org/id/ENSGALT00010026841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015295.1", "url": "https://www.ensembl.org/id/ENSGALP00010015295.1" } ] } }, { "isoform_ac": "A0A8V0YA46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA46/entry", "sequence": { "sequence": "MDLMNGQSSSVNIAATASECFCLLLQKSSSSESLSDKGSAELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPEELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILESEQRTNLMNNILRIISDLQQSCEYDIPLLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPHSAASREDLVASEVGASPQSGRKNAAAEGALLPPTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHVPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPGTRVSRNGYRGHMKASSSLESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWVALCGTQLFYYAAKSLKATERKHFKSTPSKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNRQQVPANLMTFE", "length": 591, "header": "tr|A0A8V0YA46-1|RGPS1_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=2 SV=1 CANONICAL=Q5ZJK0-1" }, "locus": { "chromosome": "8", "start_pos": 6390043, "end_pos": 6305126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026843.1", "url": "https://www.ensembl.org/id/ENSGALT00010026843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015297.1", "url": "https://www.ensembl.org/id/ENSGALP00010015297.1" } ] } }, { "isoform_ac": "Q5ZJK0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0/entry#Q5ZJK0-1", "sequence": { "sequence": "MDLMNGQSSSVNIAATASEKSSSSESLSDKGSAELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPEELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILESEQRTNLMNNILRIISDLQQSCEYDIPLLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPHSAASREDLVASEVGASPQSGRKNAAAEGALLPPTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHVPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPGTRVSRNGYRGHMKASSSLESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWVALCGTQLFYYAAKSLKATERKHFKSTPSKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNRQQVPANLMTFE", "length": 584, "header": "sp|Q5ZJK0-1|RGPS1_CHICK Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=2 SV=1 CANONICAL=Q5ZJK0-1" }, "locus": { "chromosome": "8", "start_pos": 6390043, "end_pos": 6305126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026838.1", "url": "https://www.ensembl.org/id/ENSGALT00010026838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015293.1", "url": "https://www.ensembl.org/id/ENSGALP00010015293.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 327, "start_aa": "Thr", "end_pos": 327, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr327", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424429", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424429", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTI5-1", "protein_name": "Ral GEF with PH domain and SH3 binding motif 2", "gene_name": "Ralgps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLMNGQASSVNIGATVSEKSSSSESLSEKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGASTPRSAASREDLAGPDVGASPQGGRKSSAAEGALLPQTPPSPRHLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRMPRNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYPAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQSNRQQIIGSNIMHYNFRRLNIALIFILLYQAICHDS", "length": 605 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2QNZ5-1", "protein_name": "Ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1", "gene_name": "Ralgps2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLMNGQASNVNIVATVSEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPILPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSRRKSSAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVPRNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVCVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQSNRQQVPTNLMTFE", "length": 583 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BNN3-1", "protein_name": "Ral GEF with PH domain and SH3 binding motif 2", "gene_name": "RALGPS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLMNGQASNVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELASCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSMAAEGALLPQTPPSPRNLIQHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQSNKQQVPTNLMTFE", "length": 583 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S6Y4-1", "protein_name": "Ral GEF with PH domain and SH3 binding motif 2", "gene_name": "RALGPS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLMNGQASSVNIAAAASEKSSSSESLSDRGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLTAACQSNKQQVPTNLMTFE", "length": 583 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0E949-1", "protein_name": "Ral GEF with PH domain and SH3 binding motif, isoform B", "gene_name": "RalGPS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMRYSEISRDLSTDNLRYSELSRKPTTDYNGYTGQAYAATQFKQSSPPPPPSQQQQQPTRVSKQRSPNTNGSAHTMACLRQEKTYKEQQMEPPSMQPQASKTLNIKSTRRKNSIGCLNSFSSSPDSPGCYYTIAASAAPPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPHKGGLEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQNIFEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKTIGSMRMASGTKFVPGHRKCRSLGTKFRSSSLPRNFAEKCQCCIVMIAPGIGTISNKRCRCRRIFGKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDSVLEHSDALSQADLTSLESAEGIMCDFTGSDCDLMSPEAAAAMHGCVRRKTVQKEGRKPAVASWQRYWLQIWANSLVYFPPKSFKGSERNDFKREPCKVCPLDGWYAHVSDNTKHKNTFELCHRTLGTVYRFRTDSPQMTHLWSNAICKLATMRVPKPLPTNLMSFE", "length": 702 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86X27-1", "protein_name": "Ras-specific guanine nucleotide-releasing factor RalGPS2", "gene_name": "RALGPS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE", "length": 583 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERD6-1", "protein_name": "Ras-specific guanine nucleotide-releasing factor RalGPS2", "gene_name": "Ralgps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLMNGQASSVTIAATVSEKSSSSESLSEKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPILPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGASTPRSAASREDLAGPDIGASPQGGRKSSAAAAAAAAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVPRNGYRSHTKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVVGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQSNKQQVPTNLMTFE", "length": 590 }, "evidence": [ { "id": "Q5ZJK0", "url": "https://omabrowser.org/oma/group/Q5ZJK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of Ral protein signal transduction", "id": "GO:0032485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032485", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 584, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJK0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 458, "end_pos": 570, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZJK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK0" }, { "id": "PRU00168", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00168" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000255", "start_pos": 50, "end_pos": 288, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 327 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U571-1", "uniprot_ac": "A0A3Q2U571", "uniprot_id": "A0A3Q2U571_CHICK", "mass": { "chemical_mass": 134647.0, "monoisotopic_mass": 134647.0 }, "refseq": { "ac": "XP_025008772", "name": "zinc finger protein 644 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008772" }, "gene_names": [ { "name": "ZNF644", "type": "recommended", "evidence": [ { "id": "A0A3Q2U571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ] }, { "name": "ZNF644", "type": "synonym", "evidence": [ { "id": "XP_025008772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008772" } ] } ], "protein_names": [ { "name": "Zinc finger protein 644", "type": "synonym", "evidence": [ { "id": "A0A3Q2U571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 644 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025008772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008772" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008772" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF644", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571", "locus": { "chromosome": "8", "start_pos": 14391825, "end_pos": 14319049, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022152", "url": "https://www.ensembl.org/id/ENSGALG00010022152" } ] } } ], "crossref": [ { "id": "A0A3Q2U571", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U571", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034253", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424510", "url": "https://www.ncbi.nlm.nih.gov/gene/424510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424510", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSKQANC", "url": "https://omabrowser.org/oma/group/SSKQANC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PEY0", "url": "https://www.orthodb.org/?gene=A0A1D5PEY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TTI8", "url": "https://www.orthodb.org/?gene=A0A3Q2TTI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U571", "url": "https://www.orthodb.org/?gene=A0A3Q2U571", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGL7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP26", "url": "https://www.orthodb.org/?gene=A0A8V0ZP26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUC9", "url": "https://www.orthodb.org/?gene=A0A8V0ZUC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025008772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008772", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PEY0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U571-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDLEINTEVTGAKEEEEEILCDFVSEEEGGIPESQESDTLFQKNNTLTLPEELSRDRSENALSGGQTSLFIHTGAPTVSSENFILSRGTAVNGPVSHSTSTKTSIMSKGSVSLTTGQPVGHHTDSCSTLTVVHDLQLPAKSSTENSNQHQVLFLLPDVAHAKNMTHSIKNLPTSASVGCDSQKSVGNSVDSTLVGQVEVCEDDKNLLVKDDCVDALTGISSGTGGFRSGCEPSWDPQKEFIQFLMTNEETIEKSPIHCKVGLEKKRKRKMDVSKITRYTEDCFGDTTYIPSKSKLLTVDFLEQNEELQIVEPQKYSLSKVKPESTDEELEAVDAIQQLIYSPTGSCAEDASPVHTSTFLSNTLKNKCEQNDSESPSTFSTDEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCSVIGSDISQRKSQKKASMKDPYLGSSKKSSTYMCKMCPFTTSARSILKKHMEYLHPASCIDPFGSHLRLEKRKGSIMEESLDFGSRTKQLIKQSSTFPKNSVLKQDVKRSFGSASQSSNFGKLHKRPYRIQKARKSVSQSSRLNSAEKKDSYETEDESSWDNAELCDYTTRSVEDESYSDINQEHVSLFPIFKGKMEDHEAGDKSSLSYEQNDGFYFEYYEDAESSNFLHDLHDAQNLENVGSALPKHNSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETSSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRVIPRPFVAQKFASNDDFLSQNVLPLEAYHNGLKTEDISVSASEEEGLSFLNECDETKAVLHNEKKNQSLTLIELLKNKRLGEERSPGISSQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMQSGMPVKLRTCVHCNTTFTSAVSLSNHLRAYARKKSAGLLTGTALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1198, "header": "tr|A0A3Q2U571-1|A0A3Q2U571_CHICK Isoform 1 of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEY0/entry", "sequence": { "sequence": "MDDLEINTEVTGAKEEEEEILCDFVSEEEGGIPESQESDTLFQKNNTLTLPEELSRDRSENALSGGQTSLFIHTGAPTVSSENFILSRGTAVNGPVSHSTSTKTSIMSKGSVSLTTGQPVGHHTDSCSTLTVVHDLQLPAKSSTENSNQHQVLFLLPDVAHAKNMTHSIKNLPTSASVGCDSQKSVGNSVDSTLVGQVEVCEDDKNLLVKDDCVDALTGISSGTGGFRSGCEPSWDPQKEFIQFLMTNEETIEKSPIHCKVGLEKKRKRKMDVSKITRYTEDCFGDTTYIPSKSKLLTVDFLEQNEELQIVEPQKYSLSKVKPESTDEELEAVDAIQQLIYSPTGSCAEDASPVHTSTFLSNTLKNKCEQNDSESPSTFSTDEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCSVIGSDISQRKSQKKASMKDPYLGSSKKSSTYMCKMCPFTTSARSILKKHMEYLHPASCIDPFGSHLRLEKRKGSIMEESLDFGSRTKQLIKQSSTFPKNSVLKQDVKRSFGSASQSSNFGKLHKRPYRIQKARKSVSQSSRLNSAEKKDSYETEDESSWDNAELCDYTTRSVEDESYSDINQEHVSLFPIFKGKMEDHEAGDKSSLSYEQNDGFYFEYYEDAESSNFLHDLHDAQNLENVGSALPKHNSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 955, "header": "tr|A0A1D5PEY0-1|A0A3Q2U571_CHICK Computationally mapped isoform of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14391434, "end_pos": 14377028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053884.1", "url": "https://www.ensembl.org/id/ENSGALT00010053884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032444.1", "url": "https://www.ensembl.org/id/ENSGALP00010032444.1" } ] } }, { "isoform_ac": "A0A3Q2TTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTI8/entry", "sequence": { "sequence": "MDDLEINTEVTGAKEEEEEILCDFVSEEEGGIPESQESDTLFQKNNTLTLPEELSRDRSENALSGGQTSLFIHTGAPTVSSENFILSRGTAVNGPVSHSTSTKTSIMSKGSVSLTTGQPVGHHTDSCSTLTVVHDLQLPAKSSTENSNQHQVLFLLPDVAHAKNMTHSIKNLPTSASVGCDSQKSVGNSVDSTLVGQVEVCEDDKNLLVKDDCVDALTGISSGTGGFRSGCEPSWDPQKEFIQFLMTNEETIEKSPIHCKVGLEKKRKRKMDVSKITRYTEDCFGDTTYIPSKSKLLTVDFLEQNEELQIVEPQKYSLSKVKPESTDEELEAVDAIQQLIYSPTGSCAEDASPVHTSTFLSNTLKNKCEQNDSESPSTFSTDEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCSVIGSDISQRKSQKKASMKDPYLGSSKKSSTYMCKMCPFTTSARSILKKHMEYLHPASCIDPFGSHLRLEKRKGSIMEESLDFGSRTKQLIKQSSTFPKNSVLKQDVKRSFGSASQSSNFGKLHKRPYRIQKARKSVSQSSRLNSAEKKDSYETEDESSWDNAELCDYTTRSVEDESYSDINQEHVSLFPIFKGKMEDHEAGDKSSLSYEQNDGFYFEYYEDAESSNFLHDLHDAQNLENVGSALPKHNSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETSSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRVIPRPFVAQKFASNDDFLSQNVLPLEAYHNGLKTEDISVSASEEEGLSFLNECDETKAVLHNEKKNQSLTLIELLKNKRLGEERSPGISSQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMQSALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1157, "header": "tr|A0A3Q2TTI8-1|A0A3Q2TTI8_CHICK Computationally mapped isoform of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14391434, "end_pos": 14377028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053891.1", "url": "https://www.ensembl.org/id/ENSGALT00010053891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032449.1", "url": "https://www.ensembl.org/id/ENSGALP00010032449.1" } ] } }, { "isoform_ac": "A0A3Q2U571-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571/entry", "sequence": { "sequence": "MDDLEINTEVTGAKEEEEEILCDFVSEEEGGIPESQESDTLFQKNNTLTLPEELSRDRSENALSGGQTSLFIHTGAPTVSSENFILSRGTAVNGPVSHSTSTKTSIMSKGSVSLTTGQPVGHHTDSCSTLTVVHDLQLPAKSSTENSNQHQVLFLLPDVAHAKNMTHSIKNLPTSASVGCDSQKSVGNSVDSTLVGQVEVCEDDKNLLVKDDCVDALTGISSGTGGFRSGCEPSWDPQKEFIQFLMTNEETIEKSPIHCKVGLEKKRKRKMDVSKITRYTEDCFGDTTYIPSKSKLLTVDFLEQNEELQIVEPQKYSLSKVKPESTDEELEAVDAIQQLIYSPTGSCAEDASPVHTSTFLSNTLKNKCEQNDSESPSTFSTDEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCSVIGSDISQRKSQKKASMKDPYLGSSKKSSTYMCKMCPFTTSARSILKKHMEYLHPASCIDPFGSHLRLEKRKGSIMEESLDFGSRTKQLIKQSSTFPKNSVLKQDVKRSFGSASQSSNFGKLHKRPYRIQKARKSVSQSSRLNSAEKKDSYETEDESSWDNAELCDYTTRSVEDESYSDINQEHVSLFPIFKGKMEDHEAGDKSSLSYEQNDGFYFEYYEDAESSNFLHDLHDAQNLENVGSALPKHNSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETSSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRVIPRPFVAQKFASNDDFLSQNVLPLEAYHNGLKTEDISVSASEEEGLSFLNECDETKAVLHNEKKNQSLTLIELLKNKRLGEERSPGISSQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMQSGMPVKLRTCVHCNTTFTSAVSLSNHLRAYARKKSAGLLTGTALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1198, "header": "tr|A0A3Q2U571-1|A0A3Q2U571_CHICK Isoform 1 of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14391434, "end_pos": 14377028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053897.1", "url": "https://www.ensembl.org/id/ENSGALT00010053897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032453.1", "url": "https://www.ensembl.org/id/ENSGALP00010032453.1" } ] } }, { "isoform_ac": "A0A8V0ZGL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL7/entry", "sequence": { "sequence": "MTPRAGRNPGVTHSPASPFVLMWKWISELNAKKTNKALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 134, "header": "tr|A0A8V0ZGL7-1|A0A8V0ZGL7_CHICK Computationally mapped isoform of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14391434, "end_pos": 14343519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053903.1", "url": "https://www.ensembl.org/id/ENSGALT00010053903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032458.1", "url": "https://www.ensembl.org/id/ENSGALP00010032458.1" } ] } }, { "isoform_ac": "A0A8V0ZP26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP26/entry", "sequence": { "sequence": "MDDLEINTEVTGAKEEEEEILCDFVSEEEGGIPESQESDTLFQKNNTLTLPEELSRDRSENALSGGQTSLFIHTGAPTVSSENFILSRGTAVNGPVSHSTSTKTSIMSKGSVSLTTGQPVGHHTDSCSTLTVVHDLQLPAKSSTENSNQHQVLFLLPDVAHAKNMTHSIKNLPTSASVGCDSQKSVGNSVDSTLVGQVEVCEDDKNLLVKDDCVDALTGISSGTGGFRSGCEPSWDPQKEFIQFLMTNEETIEKSPIHCKVGLEKKRKRKMDVSKITRYTEDCFGDTTYIPSKSKLLTVDFLEQNEELQIVEPQKYSLSKVKPESTDEELEAVDAIQQLIYSPTGSCAEDASPVHTSTFLSNTLKNKCEQNDSESPSTFSTDEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCSVIGSDISQRKSQKKASMKDPYLGSSKKSSTYMCKMCPFTTSARSILKKHMEYLHPASCIDPFGSHLRLEKRKGSIMEESLDFGSRTKQLIKQSSTFPKNSVLKQDVKRSFGSASQSSNFGKLHKRPYRIQKARKSVSQSSRLNSAEKKDSYETEDESSWDNAELCDYTTRSVEDESYSDINQEHVSLFPIFKGKMEDHEAGDKSSLSYEQNDGFYFEYYEDAESSNFLHDLHDAQNLENVGSALPKHNSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETSSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRVIPRPFVAQKFASNDDFLSQNVLPLEAYHNGLKTEDISVSASEEEGLSFLNECDETKAVLHNEKKNQSLTLIELLKNKRLGEERSPGISSQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMQSGKKVFLAVLTAFPNKCFNSQKMYKCRGF", "length": 1087, "header": "tr|A0A8V0ZP26-1|A0A8V0ZP26_CHICK Computationally mapped isoform of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14380909, "end_pos": 14377028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053880.1", "url": "https://www.ensembl.org/id/ENSGALT00010053880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032441.1", "url": "https://www.ensembl.org/id/ENSGALP00010032441.1" } ] } }, { "isoform_ac": "A0A8V0ZUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC9/entry", "sequence": { "sequence": "MKTNLSWLLQLHQLSATRFVLMWKWISELNAKKTNKALDCKQKKSRSRSGSKKKMLPLPHSADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 134, "header": "tr|A0A8V0ZUC9-1|A0A3Q2U571_CHICK Computationally mapped isoform of Zinc finger protein 644 OS=Gallus gallus OX=9031 GN=ZNF644 PE=4 SV=1 CANONICAL=A0A3Q2U571-1" }, "locus": { "chromosome": "8", "start_pos": 14391434, "end_pos": 14319111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053905.1", "url": "https://www.ensembl.org/id/ENSGALT00010053905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032459.1", "url": "https://www.ensembl.org/id/ENSGALP00010032459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LW98-1", "protein_name": "Zinc finger protein 644", "gene_name": "Zfp644", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLFLHRDVNKPNFRLNVLNDLANNMDDLKINTEVTGAKGELQDDNFISEKDSGVHKPKDCQTFQKNSALTLSEELSEAQSEQALSGVQSALFIPAGTAAVPSENFTVPTGAVANGPVSRSSSTKTCSMSEGSASLTSEQSTEQLATESCSTLKSVADRQLSTPPKASQHQVLFLLSDAAHTKSPTHSITKLPTSALVGHDGQNPVGNSLKSESTLLSQAEVGGGDAAAAVVRDDRVNALAAISSGTDKFRSENDTNWDPQKEFIQFLMTSEEAVDKSPAHSKVVGLEKKRKRKMDVSKITRYTEDCGGDLGRAPGKSKVLQADFLGQSEETQAIDSQSYTLPNMKPESADGDLETVDPFQHLVYSSDKCGEGNSPVHTRTLVSNSVKKKCEESDSESPVTFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTESELECHRGTAHGAAVKCPVVSSEVSQRKTQKKTVKDSVTGSSRKPAPYLCKMCPFTTSARSILKKHMEYLHSSPCMDSFGNPLGLDKRKSDSLEESVDVDSTKSLAKQQSSTFPKNSALKQDAKRTFGSSPQSSTFSKFHKRPHRVQKARKSIAQSGVNACSQSRSPHKNVMIKNSTDQKPKYFHQAPREKPNAKADGGYLYRYKCDDYRTVRKSGDSYPLPLKKEVSTLNSLHLFSSSNSHNNFISDPHNPDAKRPENEKDHKRVAVKRVLKASKESSGGEDLDSYPDFLHKMTVVVLQKLHSDKNDSYETEDDSPWDNVELGDYRAQAMEEDAYGDLTEEHVNLLPLLKSKMEGQGPGDSAALSYDQSDGFYFEYYEDGGTNNFLQDLHDPPHLENSDTPLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALSSRRIIPRPFVAQKLSSDDDFLSHNVLPLDEYHNGLKTEALSVSASEEEGLNFLNECDETKPDLPSGKKNQSLTLIELLKSRRIGEERNSALSPHKIHNQTARKRFVQKCVLPLNEDSPLIYQPHKMDLTVHSAIDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1321 }, "evidence": [ { "id": "A0A3Q2U571", "url": "https://omabrowser.org/oma/group/A0A3Q2U571/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QA22-1", "protein_name": "Zinc finger protein 644", "gene_name": "Zfp644", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLFLHQDVNKPKFRLKVLNDLANNMDDLKINTDITGAKEELQDDNNFISEKDSGVHKPKDCQTSFQKNSSLTRSEELSEDQSEQALSGGQSALFLPASTPAVPTENFPLPTGAVVNGPVSCSSSTKTSNMNEGSVSLTPGQPADQLAAESCSTLKAAADHQLSTPQKASQHQVLFLLSDVAHAKNPTHSIKKVPTSALVGCDVQNSVGNNMKSESTLLSQAEVGQGDASTVVRDDCVSALAVISSGTDEFRSENDTNWDPQKEFIQFLMTSEETVDKPPAHSKVVGLEKKRKRKMDVSKITRYTEDCYSDSGRAPGKSKILQVDFLGQNEEMQAIDSQNYTLSKVKPESAGGDLESVDTFQHLVYNSDKCGEDNSPVHTRTLISNTLKKKCEESDPESPVAFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAAVKCPVVSSEVTQRKTQKKTSVKDSVIGSSKKPATYLCKMCPFTTSARSILKKHTEYLHSSACVDSFGNPLGLDKRKNDSLEESVDVDSTKSLAKQQPSTFPKNSALKQDAKRTFGSSSQSSNFSKFHKRPHRIQKARKSIAQSGVNSCSQNKSPHKNVMVKSSTDQQPKYFHQAPREKPNARADSSYLYRHKYNNYRTIRKSGDSYPLPFKKEVNSLNSLHLFSSSNSHNFISDPHNADTKRPENEKDHKRVAVKRVAKASKKESSAGEDLDSYPDFLHKMTVVVLQKLHSDKKDSYETEDDSSWDNVELGDYTTQAMEEEAYSDLSQEHVNLLPLFKSKIEGQGPGDSAALSYDQNDGFYFEYYEDGGTNSFLQDIHDPQHLENPETPLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGNGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRIIPRPFVAQKLSSGDDFLSHNVLPLDEYHNGLKTEALSVSASEEEGLHFLSECGERKPELPSGRKNQSLTLIELLKSRRLGEERNSAVSPHKTHNQTARKRFVQKCVLPLNEDSPLIYQPQKMDLTVHSAIDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1323 }, "evidence": [ { "id": "A0A3Q2U571", "url": "https://omabrowser.org/oma/group/A0A3Q2U571/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H582-1", "protein_name": "Zinc finger protein 644", "gene_name": "ZNF644", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSFLQQDVNKTKSRLNVLNGLANNMDDLKINTDITGAKEELLDDNNFISDKESGVHKPKDCQTSFQKNNTLTLPEELSKDKSENALSGGQSSLFIHAGAPTVSSENFILPKGAAVNGPVSHSSLTKTSNMNKGSVSLTTGQPVDQPTTESCSTLKVAADLQLSTPQKASQHQVLFLLSDVAHAKNPTHSNKKLPTSASVGCDIQNSVGSNIKSDGTLINQVEVGEDGEDLLVKDDCVNTVTGISSGTDGFRSENDTNWDPQKEFIQFLMTNEETVDKAPPHSKIGLEKKRKRKMDVSKITRYTEDCFSDSNCVPNKSKMQEVDFLEQNEELQAVDSQKYALSKVKPESTDEDLESVDAFQHLIYNPDKCGEESSPVHTSTFLSNTLKKKCEESDSESPATFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAVVKCPMVTSDIAQRKTQKKTFMKDSVVGSSKKSATYICKMCPFTTSAKSVLKKHTEYLHSSSCVDSFGSPLGLDKRKNDILEEPVDSDSTKTLTKQQSTTFPKNSALKQDVKRTFGSTSQSSSFSKIHKRPHRIQKARKSIAQSGVNMCNQNSSPHKNVTIKSSVDQKPKYFHQAAKEKSNAKANSHYLYRHKYENYRMIKKSGESYPVHFKKEEASSLNSLHLFSSSSNSHNNFISDPHKPDAKRPESFKDHRRVAVKRVIKESKKESSVGGEDLDSYPDFLHKMTVVVLQKLNSAEKKDSYETEDESSWDNVELGDYTTQAIEDETYSDINQEHVNLFPLFKSKVEGQEPGENATLSYDQNDGFYFEYYEDTGSNNFLHEIHDPQHLETADASLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATSDKMQHFKRTGTGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRIIPRPFVAQKLASSDDFISQNVIPLEAYRNGLKTEALSVSASEEEGLNFLNEYDETKPELPSGKKNQSLTLIELLKNKRMGEERNSAISPQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQKMDLTMHSALDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "length": 1327 }, "evidence": [ { "id": "A0A3Q2U571", "url": "https://omabrowser.org/oma/group/A0A3Q2U571/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U571", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1072, "end_pos": 1074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U571-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1198, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U571-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U571" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U571" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 387, "end_pos": 414, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1072, "end_pos": 1074 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 45, "end_pos": 47 }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TW83-1", "uniprot_ac": "A0A3Q2TW83", "uniprot_id": "A0A3Q2TW83_CHICK", "mass": { "chemical_mass": 46203.0, "monoisotopic_mass": 46203.0 }, "refseq": { "ac": "XP_001233614", "name": "solute carrier family 35 member F1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233614" }, "gene_names": [ { "name": "SLC35F1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TW83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83" } ] }, { "name": "SLC35F1", "type": "synonym", "evidence": [ { "id": "XP_001233614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233614" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member F1", "type": "synonym", "evidence": [ { "id": "A0A3Q2TW83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member F1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233614" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83", "locus": { "chromosome": "3", "start_pos": 62751673, "end_pos": 63001451, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015035", "url": "https://www.ensembl.org/id/ENSGALG00010015035" } ] } } ], "crossref": [ { "id": "A0A3Q2TW83", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TW83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029011", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029011", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770279", "url": "https://www.ncbi.nlm.nih.gov/gene/770279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770279", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRYHWAQ", "url": "https://omabrowser.org/oma/group/VRYHWAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PIM4", "url": "https://www.orthodb.org/?gene=A0A1D5PIM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW83", "url": "https://www.orthodb.org/?gene=A0A3Q2TW83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJA4", "url": "https://www.orthodb.org/?gene=A0A8V0YJA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJC7", "url": "https://www.orthodb.org/?gene=A0A8V0YJC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR0", "url": "https://www.orthodb.org/?gene=A0A8V0YQR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GG47", "url": "https://www.orthodb.org/?gene=R4GG47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14233:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14233:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PIM4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GG47", "url": "https://www.uniprot.org/uniprotkb/R4GG47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GG47-1", "url": "https://www.uniprot.org/uniprotkb/R4GG47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSPERHRHPRHPPPPQPPPPPHLPPQPNHVVATIENLPAEGGGARSGISAPSNGVRQRIRKVLNRDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 416, "header": "tr|A0A3Q2TW83-1|A0A3Q2TW83_CHICK Isoform 1 of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PIM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIM4/entry", "sequence": { "sequence": "MRSLYLACIHAWLQRKKRTAPLHVRAVLGTGPRPAWRDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 387, "header": "tr|A0A1D5PIM4-1|A0A3Q2TW83_CHICK Computationally mapped isoform of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 62909941, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036162.1", "url": "https://www.ensembl.org/id/ENSGALT00010036162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021009.1", "url": "https://www.ensembl.org/id/ENSGALP00010021009.1" } ] } }, { "isoform_ac": "A0A3Q2TW83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83/entry", "sequence": { "sequence": "MLSPERHRHPRHPPPPQPPPPPHLPPQPNHVVATIENLPAEGGGARSGISAPSNGVRQRIRKVLNRDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 416, "header": "tr|A0A3Q2TW83-1|A0A3Q2TW83_CHICK Isoform 1 of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 62986913, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036174.1", "url": "https://www.ensembl.org/id/ENSGALT00010036174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021021.1", "url": "https://www.ensembl.org/id/ENSGALP00010021021.1" } ] } }, { "isoform_ac": "A0A8V0YJA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJA4/entry", "sequence": { "sequence": "MDRVTRDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 356, "header": "tr|A0A8V0YJA4-1|A0A3Q2TW83_CHICK Computationally mapped isoform of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 62899207, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036157.1", "url": "https://www.ensembl.org/id/ENSGALT00010036157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021006.1", "url": "https://www.ensembl.org/id/ENSGALP00010021006.1" } ] } }, { "isoform_ac": "A0A8V0YJC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC7/entry", "sequence": { "sequence": "MCCENNSRNLATDPAHNTSTSYTSAKDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 376, "header": "tr|A0A8V0YJC7-1|A0A3Q2TW83_CHICK Computationally mapped isoform of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 63001424, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036179.1", "url": "https://www.ensembl.org/id/ENSGALT00010036179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021026.1", "url": "https://www.ensembl.org/id/ENSGALP00010021026.1" } ] } }, { "isoform_ac": "A0A8V0YQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR0/entry", "sequence": { "sequence": "MILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 276, "header": "tr|A0A8V0YQR0-1|A0A3Q2TW83_CHICK Computationally mapped isoform of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=1 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 62801302, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036171.1", "url": "https://www.ensembl.org/id/ENSGALT00010036171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021018.1", "url": "https://www.ensembl.org/id/ENSGALP00010021018.1" } ] } }, { "isoform_ac": "R4GG47-1", "url": "https://www.uniprot.org/uniprotkb/R4GG47/entry", "sequence": { "sequence": "MRDLLLSVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGIVDIEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLVRYKAVHFIGIVVCILGMGCMAGADVLVGRQQGAGENKLIGDLLVLGGATLYGISNVCEEYIVRNLSRVEFLGMIGLFGSFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATAVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILVGLVLYSSTSTYVAQDPRVYKQFRNPSGPVVDLPTTGQLEPSVTYTSLGQETEEEPHVRVA", "length": 352, "header": "tr|R4GG47-1|A0A3Q2TW83_CHICK Computationally mapped isoform of Solute carrier family 35 member F1 OS=Gallus gallus OX=9031 GN=SLC35F1 PE=3 SV=2 CANONICAL=A0A3Q2TW83-1" }, "locus": { "chromosome": "3", "start_pos": 62970532, "end_pos": 62755549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036166.1", "url": "https://www.ensembl.org/id/ENSGALT00010036166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021013.1", "url": "https://www.ensembl.org/id/ENSGALP00010021013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770279", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0PA40-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": "SLC35F1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFISVALGQVLSLLICGISLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMAGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPAVDLPAAAQVEPSVTYTSLGQETEDEPHVRVA", "length": 349 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZFM3-1", "protein_name": "Solute carrier family 35, member F1", "gene_name": "Slc35f1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPPEPPQPQLQPPPPPAPPNHVVTTIENLPAEGSGCVSLSTSSRAGMRQRIRKVLNREMLISVALGQVLSLLVCGIGLTSKYLAEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGFIDLEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEESIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVSDLPSTAQVEPSVTYTSLGQETEEEPHVRVA", "length": 408 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MPY4-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": "SLC35F1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLISVALGQVLSLLICGISLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMAGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILLGLVLYSSTSTYIAQDPRVYKQFRNPSGPVVDLPATAQVEPSVTYTSLGQETEDEPHVRVA", "length": 349 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q4Z9-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": "slc35f1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMPEHQNHVVTTIETLPPESVGASTPSLYQRMKKVLNRELVLTLALGQVLSLLICGIGLTSKYLADDYHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILKRRWWKYMILGLIDIEANYLVIKAYQYTTLTSVQLLDCFVIPVVLLLSWFFLLVRYKVLHFVGVGVCLLGMGCMVGADVLVGRQQGLGDHKLLGDLLVLGGATLYGISNVCEEFIVKNLSRVEFLGMMGLFGSFFSGIQLAIMEHKELLKVQWDWQIGLLYIGFSACMFGLYSFMPVVIKRTSATAVNLSLLTADLYSLFCGLFLFQYKFSGLYLLSFFIIVLGLVLYSSSSTYVAQDPRVYKQFRNTGNALTDTPTSGHLEPSVTYTSLGQEIEEEPRIRVA", "length": 388 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F4J890-1", "protein_name": "Solute carrier family 35 protein (DUF914)", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGFDLKEIRTKKTLIGLGLGQLLSLLATSNGFTSSELARKGINVPTSQCFLNYVLLAIVYGSIMLYRRSDIKAKWYYYFLLAFVDVEANFLVVKAYQYTSLTSVMLLDCWAIPCVLVLTWFYLKTKYRLMKISGVFICIVGVFMVVFSDVHAGDRAGGSNPVKGDFLVLAGATLYAVSNTSEEFLVKNADTVELMTFLGFFGAIISAIQVSILERDELKAIHWSTGAVGFLAMAISILTSANQRRHILVYLLHFSRFQVFPFLRFTLTMFLFYPLVPVLLKTNGATMFNLSLLTSDMWAVLIRTFGYHEKVDWLYFLAFATTATGLIIYSMKEKDQEEHRFEEVGDEAAMQRKLLGEDDEPGT", "length": 363 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54KZ9-1", "protein_name": "Solute carrier family 35 member F2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGIISSIKESSFFKSGFIDKRLIKKRLTGLALGQLLSVMIAGTGIFSQLLVKKYGVNIPTTQSLLNYILLCVYLLVLVKRGVLWETIKTKSIYFAPLALVDLEANYIVVKAYQYTTITSVMLLDCFTIPCVVVLSRIFLKTRFTFVHIIAVLIALAGMAILVVSDIIEGESANGGSNPLLGDFLCLASSVCYAISNVGQEATVKKYDRVTYLAMIGLYGSIFCGIQIAILERNELATMAWSGGVVGYIVGFALCLFIMYSFTPTMMEIAGATVMNLSLLTSDMFGIIVAIFVFDRDLSWLYFLSFFVIVSALVIYNLSAPHVKSSEVQNLINNDNSNNNNISNYNNGSLNDSSNNNNNSNNNSSDLTNSSTNLILDNGDEITPGGADILSSTVDEITTSGESEENLNGLENNENNV", "length": 417 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5T1Q4-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": "SLC35F1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLNREMLISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEPSVTYTSLGQETEEEPHVRVA", "length": 408 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGK5-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": "Slc35f1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPPEPPQPQLQPPPPPAPPNHVVTTIENLPAEGSGGVSLSASSRASMRQRIRKVLNREMLISVALGQVLSLLVCGIGLTSKYLAEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSVQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEESIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYIAQDPRVYKQFRNPSGPVVDLPSTAQVEPSVTYTSLGQETEEEPHVRVA", "length": 408 }, "evidence": [ { "id": "A0A3Q2TW83", "url": "https://omabrowser.org/oma/group/A0A3Q2TW83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TW83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 416, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TW83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TW83" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U9E5-1", "uniprot_ac": "A0A3Q2U9E5", "uniprot_id": "A0A3Q2U9E5_CHICK", "mass": { "chemical_mass": 34562.0, "monoisotopic_mass": 34562.0 }, "refseq": { "ac": "XP_015148567", "name": "monoglyceride lipase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148567" }, "gene_names": [ { "name": "MGLL", "type": "recommended", "evidence": [ { "id": "A0A3Q2U9E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ] }, { "name": "MGLL", "type": "synonym", "evidence": [ { "id": "XP_015148567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148567" } ] } ], "protein_names": [ { "name": "Monoglyceride lipase", "type": "recommended", "evidence": [ { "id": "A0A3Q2U9E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.23", "type": "synonym", "evidence": [ { "id": "A0A3Q2U9E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5/entry#names_and_taxonomy" } ] }, { "name": "Monoacylglycerol lipase", "type": "synonym", "evidence": [ { "id": "A0A3Q2U9E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5/entry#names_and_taxonomy" } ] }, { "name": "monoglyceride lipase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015148567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148567" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148567" } ] }, { "annotation": "Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5#function" }, { "database": "UniProtKB", "id": "ARBA00058731", "url": "https://www.uniprot.org/uniprotkb/ARBA00058731#function" }, { "database": "UniProtKB", "id": "A0A1D5PK92", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK92#function" }, { "database": "UniProtKB", "id": "A0A8V1A991", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A991#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MGLL", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5", "locus": { "chromosome": "12", "start_pos": 9849233, "end_pos": 9756984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026973", "url": "https://www.ensembl.org/id/ENSGALG00010026973" } ] } } ], "crossref": [ { "id": "A0A3Q2U9E5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032736", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032736", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416024", "url": "https://www.ncbi.nlm.nih.gov/gene/416024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416024", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416024", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PK92", "url": "https://www.orthodb.org/?gene=A0A1D5PK92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9E5", "url": "https://www.orthodb.org/?gene=A0A3Q2U9E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A991", "url": "https://www.orthodb.org/?gene=A0A8V1A991", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1482883", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482883", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-426048", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "26132", "url": "https://www.rhea-db.org/rhea/26132", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34019", "url": "https://www.rhea-db.org/rhea/34019", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44688", "url": "https://www.rhea-db.org/rhea/44688", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PK92", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A991", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A991-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKHKGHSSRMPEESSPKRSPQNIPYKDLPHIVNADGQHLFCRYWKPAAAARALVFIAHGAGEHCGRYDDLAQRLTELNLFVFAHDHVGHGQSEGDRMVVSDFHVFIRDSLQHIDLMKKDHPGLPILILGHSMGGAISILTASERPGDFSGMLLISPLVVASPEVATPIKVFAAKVLNLVLPNLSLGSIDPSAISRNKKEMESYTSDPLVYHGGMKVSFVIQLMNAITRIERALPKLTLPILVLHGSSDKLCDIKGSYLLMDTVQSQDKTLKVYEEAYHALHKELPEVTTSVFTEILTWVSQKVSAAGETSQT", "length": 314, "header": "tr|A0A3Q2U9E5-1|A0A3Q2U9E5_CHICK Isoform 1 of Monoglyceride lipase OS=Gallus gallus OX=9031 GN=MGLL PE=1 SV=1 CANONICAL=A0A3Q2U9E5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK92/entry", "sequence": { "sequence": "MKTGHSSRMPEESSPKRSPQNIPYKDLPHIVNADGQHLFCRYWKPAAAARALVFIAHGAGEHCGRYDDLAQRLTELNLFVFAHDHVGHGQSEGDRMVVSDFHVFIRDSLQHIDLMKKDHPGLPILILGHSMGGAISILTASERPGDFSGMLLISPLVVASPEVATPIKVFAAKVLNLVLPNLSLGSIDPSAISRNKKEMESYTSDPLVYHGGMKVSFVIQLMNAITRIERALPKLTLPILVLHGSSDKLCDIKGSYLLMDTVQSQDKTLKVYEEAYHALHKELPEVTTSVFTEILTWVSQKVSAAGETSQT", "length": 311, "header": "tr|A0A1D5PK92-1|A0A3Q2U9E5_CHICK Computationally mapped isoform of Monoglyceride lipase OS=Gallus gallus OX=9031 GN=MGLL PE=1 SV=1 CANONICAL=A0A3Q2U9E5-1" }, "locus": { "chromosome": "12", "start_pos": 9846769, "end_pos": 9793747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065390.1", "url": "https://www.ensembl.org/id/ENSGALT00010065390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039793.1", "url": "https://www.ensembl.org/id/ENSGALP00010039793.1" } ] } }, { "isoform_ac": "A0A3Q2U9E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5/entry", "sequence": { "sequence": "MSSKHKGHSSRMPEESSPKRSPQNIPYKDLPHIVNADGQHLFCRYWKPAAAARALVFIAHGAGEHCGRYDDLAQRLTELNLFVFAHDHVGHGQSEGDRMVVSDFHVFIRDSLQHIDLMKKDHPGLPILILGHSMGGAISILTASERPGDFSGMLLISPLVVASPEVATPIKVFAAKVLNLVLPNLSLGSIDPSAISRNKKEMESYTSDPLVYHGGMKVSFVIQLMNAITRIERALPKLTLPILVLHGSSDKLCDIKGSYLLMDTVQSQDKTLKVYEEAYHALHKELPEVTTSVFTEILTWVSQKVSAAGETSQT", "length": 314, "header": "tr|A0A3Q2U9E5-1|A0A3Q2U9E5_CHICK Isoform 1 of Monoglyceride lipase OS=Gallus gallus OX=9031 GN=MGLL PE=1 SV=1 CANONICAL=A0A3Q2U9E5-1" }, "locus": { "chromosome": "12", "start_pos": 9846769, "end_pos": 9757514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065395.1", "url": "https://www.ensembl.org/id/ENSGALT00010065395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039796.1", "url": "https://www.ensembl.org/id/ENSGALP00010039796.1" } ] } }, { "isoform_ac": "A0A8V1A991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A991/entry", "sequence": { "sequence": "MRAAASGHSSRMPEESSPKRSPQNIPYKDLPHIVNADGQHLFCRYWKPAAAARALVFIAHGAGEHCGRYDDLAQRLTELNLFVFAHDHVGHGQSEGDRMVVSDFHVFIRDSLQHIDLMKKDHPGLPILILGHSMGGAISILTASERPGDFSGMLLISPLVVASPEVATPIKVFAAKVLNLVLPNLSLGSIDPSAISRNKKEMESYTSDPLVYHGGMKVSFVIQLMNAITRIERALPKLTLPILVLHGSSDKLCDIKGSYLLMDTVQSQDKTLKVYEEAYHALHKELPEVTTSVFTEILTWVSQKVSAAGETSQT", "length": 314, "header": "tr|A0A8V1A991-1|A0A3Q2U9E5_CHICK Computationally mapped isoform of Monoglyceride lipase OS=Gallus gallus OX=9031 GN=MGLL PE=1 SV=1 CANONICAL=A0A3Q2U9E5-1" }, "locus": { "chromosome": "12", "start_pos": 9846769, "end_pos": 9793369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065393.1", "url": "https://www.ensembl.org/id/ENSGALT00010065393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039794.1", "url": "https://www.ensembl.org/id/ENSGALP00010039794.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416024", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416024", "resource": "KEGG Pathway" }, { "id": "R-GGA-1482883", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482883", "resource": "Reactome", "description": "Acyl chain remodeling of DAG and TAG" }, { "id": "R-GGA-426048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426048", "resource": "Reactome", "description": "Arachidonate production from DAG" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "varicosity", "id": "GO:0043196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043196", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "cerebellar climbing fiber to Purkinje cell synapse", "id": "GO:0150053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150053", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "acylglycerol catabolic process", "id": "GO:0046464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046464", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "regulation of retrograde trans-synaptic signaling by endocanabinoid", "id": "GO:0099178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099178", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "regulation of sensory perception of pain", "id": "GO:0051930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "regulation of endocannabinoid signaling pathway", "id": "GO:2000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000124", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "monoacylglycerol catabolic process", "id": "GO:0052651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052651", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" }, { "name": "arachidonate metabolic process", "id": "GO:0019369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9E5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26132", "name": "", "equation": "2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C7F4-1", "A0A8V0X804-1", "Q5ZIN0-1", "A0A3Q2U9E5-1", "F1P1V6-1", "A0A8V0ZKJ9-1", "A0A8V1ACD9-1" ], "evidence": [ { "id": "26132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26132" } ] }, { "id": "34019", "name": "", "equation": "a 1-acylglycerol + H2O = glycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U9E5-1" ], "evidence": [ { "id": "34019", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34019" } ] }, { "id": "44688", "name": "", "equation": "a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U9E5-1" ], "evidence": [ { "id": "44688", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44688" } ] }, { "id": "R-GGA-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1500593" ], "enzyme_list": [ "A0A3Q2U9E5-1" ], "evidence": [ { "id": "R-GGA-1482543", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1482543" } ] }, { "id": "R-GGA-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"uniprot_id": "CYRIA_CHICK", "mass": { "chemical_mass": 37314.0, "monoisotopic_mass": 37314.0 }, "refseq": { "ac": "NP_001006418", "name": "CYFIP-related Rac1 interactor A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" }, "gene_names": [ { "name": "CYRIA", "type": "recommended", "evidence": [ { "id": "Q5ZI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ] }, { "name": "FAM49A", "type": "recommended", "evidence": [ { "id": "Q5ZI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ] }, { "name": "CYRIA", "type": "synonym", "evidence": [ { "id": "NP_001006418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" } ] }, { "name": "FAM49A", "type": "synonym", "evidence": [ { "id": "NP_001006418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" }, { "id": "Q5ZI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ] }, { "name": "RCJMB04_31l4", "type": "synonym", "evidence": [ { "id": "Q5ZI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ] } ], "protein_names": [ { "name": "CYFIP-related Rac1 interactor A", "type": "recommended", "evidence": [ { "id": "Q5ZI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04/entry#names_and_taxonomy" } ] }, { "name": "CYFIP-related Rac1 interactor A", "type": "synonym", "evidence": [ { "id": "NP_001006418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" } ] }, { "name": "protein FAM49A", "type": "synonym", "evidence": [ { "id": "NP_001006418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720980.1, SRR13267654.208236.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000066.1. On Jan 13, 2005 this sequence version replaced XP_419961.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418" } ] }, { "annotation": "May negatively regulate RAC1 signaling and RAC1-driven cytoskeletal remodeling. May regulate chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04#function" }, { "database": "UniProtKB", "id": "Q9H0Q0", "url": "https://www.uniprot.org/uniprotkb/Q9H0Q0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYRIA", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04", "locus": {} } ], "crossref": [ { "id": "Q5ZI04", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI04", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016463", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016463", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421949", "url": "https://www.ncbi.nlm.nih.gov/gene/421949", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421949", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421949", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PP47", "url": "https://www.orthodb.org/?gene=A0A1D5PP47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X918", "url": "https://www.orthodb.org/?gene=A0A8V0X918", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XC38", "url": "https://www.orthodb.org/?gene=A0A8V0XC38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XET4", "url": "https://www.orthodb.org/?gene=A0A8V0XET4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI04", "url": "https://www.orthodb.org/?gene=Q5ZI04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI04", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI04", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PP47", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PP47-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X918", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X918", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X918-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X918-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XET4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XET4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI04-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNLLKVLTREIENYPHFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 323, "header": "sp|Q5ZI04-1|CYRIA_CHICK Isoform 1 of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PP47-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PP47/entry", "sequence": { "sequence": "MGNLLKVLTCTELDQGPNFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 324, "header": "tr|A0A1D5PP47-1|CYRIA_CHICK Computationally mapped isoform of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "locus": { "chromosome": "3", "start_pos": 99304463, "end_pos": 99286265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005296.1", "url": "https://www.ensembl.org/id/ENSGALT00010005296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003135.1", "url": "https://www.ensembl.org/id/ENSGALP00010003135.1" } ] } }, { "isoform_ac": "A0A8V0X918-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X918/entry", "sequence": { "sequence": "MFALGCCLPAPEGGACVERINGDRGVFAVLFFSSPSARLPPLSKYQEGSGTSSTRQTLNVLHQHFGFSNVNWNYFISRFAGMGNLLKVLTREIENYPHFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 404, "header": "tr|A0A8V0X918-1|CYRIA_CHICK Computationally mapped isoform of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "locus": { "chromosome": "3", "start_pos": 99336764, "end_pos": 99286265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005300.1", "url": "https://www.ensembl.org/id/ENSGALT00010005300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003139.1", "url": "https://www.ensembl.org/id/ENSGALP00010003139.1" } ] } }, { "isoform_ac": "A0A8V0XC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC38/entry", "sequence": { "sequence": "MIIDLFLWGLPPLSKYQEGSGTSSTRQTLNVLHQHFGFSNVNWNYFISRFAGMGNLLKVLTREIENYPHFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 375, "header": "tr|A0A8V0XC38-1|CYRIA_CHICK Computationally mapped isoform of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "locus": { "chromosome": "3", "start_pos": 99321772, "end_pos": 99286265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005298.1", "url": "https://www.ensembl.org/id/ENSGALT00010005298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003137.1", "url": "https://www.ensembl.org/id/ENSGALP00010003137.1" } ] } }, { "isoform_ac": "A0A8V0XET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XET4/entry", "sequence": { "sequence": "MRFAGMGNLLKVLTREIENYPHFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 328, "header": "tr|A0A8V0XET4-1|CYRIA_CHICK Computationally mapped isoform of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "locus": { "chromosome": "3", "start_pos": 99306434, "end_pos": 99286265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005293.1", "url": "https://www.ensembl.org/id/ENSGALT00010005293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003132.1", "url": "https://www.ensembl.org/id/ENSGALP00010003132.1" } ] } }, { "isoform_ac": "Q5ZI04-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04/entry#Q5ZI04-1", "sequence": { "sequence": "MGNLLKVLTREIENYPHFFLDFENAQPTDGEREVWNQISAVLQDSESMLADLQAYKGAGQEIRDAIQNPNDIQLQEKAWNSVCPLVVRLKRFYEFSLRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATTHFVSENKTLPIENTTDCLSTMASVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFSKTSKIDMKGCIKVLKEQPPDTVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "length": 323, "header": "sp|Q5ZI04-1|CYRIA_CHICK Isoform 1 of CYFIP-related Rac1 interactor A OS=Gallus gallus OX=9031 GN=CYRIA PE=2 SV=1 CANONICAL=Q5ZI04-1" }, "locus": { "chromosome": "3", "start_pos": 99304729, "end_pos": 99286265, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005295.1", "url": "https://www.ensembl.org/id/ENSGALT00010005295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003134.1", "url": "https://www.ensembl.org/id/ENSGALP00010003134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421949", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421949", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI04", "url": "https://www.uniprot.org/uniprotkb/Q5ZI04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI04-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI04-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI04" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U6L6-1", "uniprot_ac": "A0A3Q2U6L6", "uniprot_id": "A0A3Q2U6L6_CHICK", "mass": { "chemical_mass": 124103.0, "monoisotopic_mass": 124103.0 }, "refseq": { "ac": "XP_004950876", "name": "GEM-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950876" }, "gene_names": [ { "name": "GMIP", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ] }, { "name": "GMIP", "type": "synonym", "evidence": [ { "id": "XP_004950876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950876" } ] } ], "protein_names": [ { "name": "GEM interacting protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2U6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6/entry#names_and_taxonomy" } ] }, { "name": "GEM-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004950876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950876" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052561.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004950876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950876" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GMIP", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6", "locus": { "chromosome": "30", "start_pos": 660232, "end_pos": 682083, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003439", "url": "https://www.ensembl.org/id/ENSGALG00010003439" } ] } } ], "crossref": [ { "id": "A0A3Q2U6L6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029354", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029354", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426010", "url": "https://www.ncbi.nlm.nih.gov/gene/426010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426010", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426010", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVKYYRH", "url": "https://omabrowser.org/oma/group/PVKYYRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PTT2", "url": "https://www.orthodb.org/?gene=A0A1D5PTT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U6L6", "url": "https://www.orthodb.org/?gene=A0A3Q2U6L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AP23", "url": "https://www.orthodb.org/?gene=A0A3Q3AP23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9K7", "url": "https://www.orthodb.org/?gene=A0A8V0X9K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGG2", "url": "https://www.orthodb.org/?gene=A0A8V0XGG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004950876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PTT2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PTT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U6L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AP23", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AP23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AP23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGLGSRDDARVADGFPAGFLPPEHNSHLGIPAASWAPSHCPTPEHRAGEVLRVTQHLKSIDGKFQCLRELFQKGEDFSGPVKAKLSDLLHSIFSFLNTYPAVTGDAIHLAIATLIANINGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGEQSVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLENPSSKHSSSVDDVSDISSSGEAMDGFMLESAHSSEGGEVNASVGSELEDAEEKADSDSEPVFGTQPRGHFSRQPVKYVRAQPKTRPNIPKPSSLPLRATTSPSMATDSGAEGSPIDSTCMGKEILEERTRSRNSSPDMSALRHKGKQHKHFQITEETARIISKFKADEVSAAPELSSGEKAVKFGPEIIPEKIL", "length": 1112, "header": "tr|A0A3Q2U6L6-1|A0A3Q2U6L6_CHICK Isoform 1 of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=1 CANONICAL=A0A3Q2U6L6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PTT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTT2/entry", "sequence": { "sequence": "MGDPEQSGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGEQSVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLENPSSKHSSSVDDVSDISSSGEAMDGFMLESAHSSEGGEVNASVGSELEDAEEKADSDSEPVFGTQPRGHFSRQPVKYVRAQPKTRPNIPKPSSLPLRATTSPSMATDSGAEGSPIDSTCMGKEILEERTRSRNSSPDMSALRHKGKQHKHFQITEETARIISKFKADEVSAAPELSSGEKAVKFGPEIIPEKIL", "length": 999, "header": "tr|A0A1D5PTT2-1|A0A3Q2U6L6_CHICK Computationally mapped isoform of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=2 CANONICAL=A0A3Q2U6L6-1" }, "locus": { "chromosome": "30", "start_pos": 677381, "end_pos": 661709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008017.1", "url": "https://www.ensembl.org/id/ENSGALT00010008017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004803.1", "url": "https://www.ensembl.org/id/ENSGALP00010004803.1" } ] } }, { "isoform_ac": "A0A3Q2U6L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6/entry", "sequence": { "sequence": "MNGLGSRDDARVADGFPAGFLPPEHNSHLGIPAASWAPSHCPTPEHRAGEVLRVTQHLKSIDGKFQCLRELFQKGEDFSGPVKAKLSDLLHSIFSFLNTYPAVTGDAIHLAIATLIANINGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGEQSVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLENPSSKHSSSVDDVSDISSSGEAMDGFMLESAHSSEGGEVNASVGSELEDAEEKADSDSEPVFGTQPRGHFSRQPVKYVRAQPKTRPNIPKPSSLPLRATTSPSMATDSGAEGSPIDSTCMGKEILEERTRSRNSSPDMSALRHKGKQHKHFQITEETARIISKFKADEVSAAPELSSGEKAVKFGPEIIPEKIL", "length": 1112, "header": "tr|A0A3Q2U6L6-1|A0A3Q2U6L6_CHICK Isoform 1 of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=1 CANONICAL=A0A3Q2U6L6-1" }, "locus": { "chromosome": "30", "start_pos": 681379, "end_pos": 661709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008020.1", "url": "https://www.ensembl.org/id/ENSGALT00010008020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004804.1", "url": "https://www.ensembl.org/id/ENSGALP00010004804.1" } ] } }, { "isoform_ac": "A0A3Q3AP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AP23/entry", "sequence": { "sequence": "MRTCRKPNDGIGNWDGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGEQSVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLEVELADTELGLLTLL", "length": 827, "header": "tr|A0A3Q3AP23-1|A0A3Q2U6L6_CHICK Computationally mapped isoform of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=1 CANONICAL=A0A3Q2U6L6-1" }, "locus": { "chromosome": "30", "start_pos": 678947, "end_pos": 663787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008010.1", "url": "https://www.ensembl.org/id/ENSGALT00010008010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004799.1", "url": "https://www.ensembl.org/id/ENSGALP00010004799.1" } ] } }, { "isoform_ac": "A0A8V0X9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9K7/entry", "sequence": { "sequence": "MGDPEQSGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGEQSVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLEVELADTELGLLTLL", "length": 819, "header": "tr|A0A8V0X9K7-1|A0A3Q2U6L6_CHICK Computationally mapped isoform of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=1 CANONICAL=A0A3Q2U6L6-1" }, "locus": { "chromosome": "30", "start_pos": 677381, "end_pos": 663787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008000.1", "url": "https://www.ensembl.org/id/ENSGALT00010008000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004792.1", "url": "https://www.ensembl.org/id/ENSGALP00010004792.1" } ] } }, { "isoform_ac": "A0A8V0XGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGG2/entry", "sequence": { "sequence": "MARLKGLDHQERAPENKKRYSEIFRSLDAIEISIGNAAVDMFIGDADGTGDAELSTEREIIVPSEDLSKSKSSLERQMQGDLTVEEADEMLIKCEGGIDAALEYAKMWCKYVKELLSWIEKRLNYETEFAKGIMKIAESGRNAIIHQSNMPLRMLYVMVLENDIKIGNAASETVGLLQQKEFYQPLSAKKNEIEKWRKEFKDQWTKEQKRMNESLSLLRKARLQYIQRCEEMEKAKQLSAKAEDEYQNSAIISPSSAIKHLEKRRRSCEEAQAKVQEAEALYRMCIGDANFRRQELEKVRARIVSHIRKLIYQGDEVLTWVTLRMFKQRQTQSEQIPVGYQHLSEVCKPYRVGEKYLEFIQALQKKDIPMEHFEFEPLSSGGQRSPPSNKKKTPLHYTGCSKDGSTPEDTPRRQFSPNGVNKSLCSDTESLSGSCESRSLDSPSSSPGNSTRKLLKASSTGTMSSSDDFEERDSLQTSENENGTSQQQFRNALLSSAAQTHRLRKLRGPTKCRECDTFMVNGFECEECYLTCHKKCLENLLITCGHKKLPNRVPLFGIDFTQVPRDFPEEVPFIVVKCTSEIEARALGVQGIYRISGSKARVEKLCQAFENGRSLVELSEHSPHDITGVLKHFLKELSGPILLYQLYDNLIALAKELQKAGEEKVDCTSFPSDPIQSMKDLLSKLPGSNYNTLRHLIAHLYRVAEKYEENKMSPNNLGIVFGPTLIRPGSGSDVSMSCLVDSGYQAQIVEFLIQNYERVFGMEDLPSSLSLGCENPLQEASTEKDEEHQSPNTAQNVTLEVELADTELGLLTLL", "length": 814, "header": "tr|A0A8V0XGG2-1|A0A3Q2U6L6_CHICK Computationally mapped isoform of GEM interacting protein OS=Gallus gallus OX=9031 GN=GMIP PE=4 SV=1 CANONICAL=A0A3Q2U6L6-1" }, "locus": { "chromosome": "30", "start_pos": 675554, "end_pos": 663787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007986.1", "url": "https://www.ensembl.org/id/ENSGALT00010007986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004784.1", "url": "https://www.ensembl.org/id/ENSGALP00010004784.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426010", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426010", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IQD4-1", "protein_name": "Endoplasmic reticulum transmembrane helix translocase", "gene_name": "Atp13a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVGNAVPCGTRPGAAGGNGPPQPGRRPRPLLAAGPALIASGDELVAAVWPYRRLALVRRLTVLPFAGLLYPAWLGAAASGCWGWGSSWTQVPEAALLALATICLAHALTVLSGHWSVHAHCALTCTPEYDPSRATFVKVVPTPNNGSTELVALHRDKGEDGLEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPVASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADARLHVIFGGTKVVQHMPPQKATSGLKSVDNGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWVEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPIETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIDKAHTLILHPPSEKGRPCEWRSIDSSIVLPLTLGSPKALALEHALCLTGDGLAHLQAVDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERIVERRRRPRDNQVLSNSGPRVSSRSTKQRSALLSPEEPPASHRDRLNQVLRDLEDESTPIVKLGDASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQGLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFSVHFLSLVYLYQEAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLVVSLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIGQVLALDFCLALLADRVLQFFLGTPKLKVPS", "length": 1201 }, "evidence": [ { "id": "A0A3Q2U6L6", "url": "https://omabrowser.org/oma/group/A0A3Q2U6L6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8W4FPG2-1", "protein_name": "GEM interacting protein", "gene_name": "GMIP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWQGLPPAPENRKRYSDIFRSLDNLEISLGNVTLEMLAADPVLSAGDPETDKTPTATLSNETSSWSGPSPEDPAPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASHELEFAKTIMKIAEAGKVSIHQQSHMPLQYIYTLFLEHDLSLGALAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYAQRSEDLRVRSQVSPEDPAPQASPALNKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEAAKQRIVSHVRKLVLQGDEVLRRVTLGLFRLREAQAERGPRAFAALAECCAPFEPGQRYQEFVRTMQPDAPPPPPPAFSFQEFSYSSPLDTRKKLSDPSPPRLDESGADPGPWEDTGTGWQGTLGSDVDSLGGGSESRSLDSPTSSPGSGTRRLVKVSSIGTESSDDFEERDPDLGDGLENGPGTPFKKWTLSNAAQTHRLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHRRLPARTPIFGVNFLQLPRDFPEEVPFVITRCTAEIEQRALGVQGIYRVSGSRVRVERLCQAFENGRALVDLSGNSPHDISSVLKRFLQELTDPVVPFHLYDAFISLAKTLHADPGRDPGTPSPSPEIICSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLLRPPDGPGAACAGPVTCLLDSGHQAQLIEFLIVHYEKIFGIDELPLTTEPLPRDPSPPPGALPTNTQPSYPQLVLDPLPLSLTSDPNPAPMPLSALEEHPEATLPEIPTLQCDQGEEVAKDTKDEGGEVSSQGLQDSPLGTQSRGHFSRQPVKYPRGGVRPVTHQLSGLALVASKLCEETPVTSVPQGSLRRRGPGPTATSCEGSPLRRAPLPKHFEITQETARLLSKLHSESVPKATCCPDPQPEEAEDHL", "length": 959 }, "evidence": [ { "id": "A0A3Q2U6L6", "url": "https://omabrowser.org/oma/group/A0A3Q2U6L6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZA46-1", "protein_name": "Gem-interacting protein", "gene_name": "Gmip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSTETELTPAPEGRKRYSDIFQSLDNLEISLGNVTFDPLAGDLVLREDLEPDKTDTAAVETEENSEASWSNPSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKNIMKIAEAGKGSILQQSQMPLQYIYTLFLEHDHSLGALAIDTVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMSEAEQALRRSQLQYIQRREDLRARTQGSPEDPPLQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANTRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRSLQPGAPPPPSPAFCFQEFAPVVHSFPQDTKKKFSGPLPTRLEEGPSEPGPWEVASLGSQGIPGSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLGDGMENGTGSPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHQRLPARMPLFGVDFLQLPRDFPEEVPFVVTRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHFYDAFISLAKTLHADPGDDPGTPSPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFKENKMSANNLGIVFGPTLLRPPDGPGATSASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLTSEPLTQDPALAPALLESSPQHPALLVAQDSQPLTIASDSSPDPKQHSALEKCPKVAPPELTALQSNRKEEEEEDTRDGAGDGSSHSPEDLLLVAQSRGHFSRQPVKYSRGGVRPVTHQLSSLALVASKLCEETPITVSAVHRGSLRARGLGPAAASPEGGTLRRNPLPKHFEITQETARLLSKLDSEAVSRTSCCADPEPEESEEHL", "length": 969 }, "evidence": [ { "id": "A0A3Q2U6L6", "url": "https://omabrowser.org/oma/group/A0A3Q2U6L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PGG2-1", "protein_name": "GEM-interacting protein", "gene_name": "Gmip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAETELTPAPEGRKRYSDIFQSLDNLEISLGNVTFDPLAGDPVRREDLEPDKADTATVVTEENSEASSWRDLSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKSIMKLAEAGKVSILQQSQMPLQYIYTLFLEHDLSLGALALETVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMNEAVQALRRSELQYIQRREDLRARSQGSPEDPPSQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANSRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRTLQPGAPPPPSPAFCFQEFTAVVHSFPQDTKKKFSGPLPPRLEEEGSPEPGPWEVASLGSQGIPGSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLGDGIENGVGSPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHRRLPARMSLFGVDFLQLPRDFPEEVPFVITRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHLYDAFISLAKTLHADPGDDPGTPNPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLLRPPDGPRATGASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLASEPLTQDPGLAPACLESSPQHPASLLAQDTQPLTIALDSSPDPKHHSALEKCPEVTPPELATLQRDQREEEVEDTRDGAGDGSSHCPEDLALGAQSRGHFSRQPVKYSRGGVRPVTHQLSSLALVASKLCEETPVTVSAVHRGSLRVRGLGPAAACPEGSPLRRNPLPKHFEITQETARLLSKLNSDAVSRTTCCADPEPEESEEHL", "length": 971 }, "evidence": [ { "id": "A0A3Q2U6L6", "url": "https://omabrowser.org/oma/group/A0A3Q2U6L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6L6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U6L6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1112, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U6L6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6L6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TWK9-1", "uniprot_ac": "A0A3Q2TWK9", "uniprot_id": "A0A3Q2TWK9_CHICK", "mass": { "chemical_mass": 35039.0, "monoisotopic_mass": 35039.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM241", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" } ] } ], "protein_names": [ { "name": "Transmembrane protein 241", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM241", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9", "locus": { "chromosome": "2", "start_pos": 102548730, "end_pos": 102636182, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004244", "url": "https://www.ensembl.org/id/ENSGALG00010004244" } ] } } ], "crossref": [ { "id": "A0A3Q2TWK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035384", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035384", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421073", "url": "https://www.ncbi.nlm.nih.gov/gene/421073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PUI3", "url": "https://www.orthodb.org/?gene=A0A1D5PUI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RP49", "url": "https://www.orthodb.org/?gene=A0A1L1RP49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TWK9", "url": "https://www.orthodb.org/?gene=A0A3Q2TWK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCE7", "url": "https://www.orthodb.org/?gene=A0A8V0XCE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCG7", "url": "https://www.orthodb.org/?gene=A0A8V0XCG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJ64", "url": "https://www.orthodb.org/?gene=A0A8V0XJ64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJ78", "url": "https://www.orthodb.org/?gene=A0A8V0XJ78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XM14", "url": "https://www.orthodb.org/?gene=A0A8V0XM14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XNM9", "url": "https://www.orthodb.org/?gene=A0A8V0XNM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XNP9", "url": "https://www.orthodb.org/?gene=A0A8V0XNP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PUI3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PUI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP49", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RP49-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XM14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XNP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISWDEDNDNFGKDVLPVRPKAEFPLTGTDRFNGLRVFVP", "length": 313, "header": "tr|A0A3Q2TWK9-1|A0A3Q2TWK9_CHICK Isoform 1 of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PUI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUI3/entry", "sequence": { "sequence": "SGRRAASPSASSTWRPASPTRWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISCLVISGVGEALLVYTERTGT", "length": 277, "header": "tr|A0A1D5PUI3-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=2 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636090, "end_pos": 102583579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009935.1", "url": "https://www.ensembl.org/id/ENSGALT00010009935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005818.1", "url": "https://www.ensembl.org/id/ENSGALP00010005818.1" } ] } }, { "isoform_ac": "A0A1L1RP49-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RP49/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISCLVISGVGEALLVYTERTGT", "length": 296, "header": "tr|A0A1L1RP49-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=2 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102583579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009937.1", "url": "https://www.ensembl.org/id/ENSGALT00010009937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005820.1", "url": "https://www.ensembl.org/id/ENSGALP00010005820.1" } ] } }, { "isoform_ac": "A0A3Q2TWK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISWDEDNDNFGKDVLPVRPKAEFPLTGTDRFNGLRVFVP", "length": 313, "header": "tr|A0A3Q2TWK9-1|A0A3Q2TWK9_CHICK Isoform 1 of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102550425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009949.1", "url": "https://www.ensembl.org/id/ENSGALT00010009949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005832.1", "url": "https://www.ensembl.org/id/ENSGALP00010005832.1" } ] } }, { "isoform_ac": "A0A8V0XCE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCE7/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKSENKGYAHQKFFSRCFEKMT", "length": 275, "header": "tr|A0A8V0XCE7-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102592541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009924.1", "url": "https://www.ensembl.org/id/ENSGALT00010009924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005807.1", "url": "https://www.ensembl.org/id/ENSGALP00010005807.1" } ] } }, { "isoform_ac": "A0A8V0XCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCG7/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKKKQKTLHGRVYGMQFQNRTGDMEWMISRTT", "length": 285, "header": "tr|A0A8V0XCG7-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102572250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009944.1", "url": "https://www.ensembl.org/id/ENSGALT00010009944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005827.1", "url": "https://www.ensembl.org/id/ENSGALP00010005827.1" } ] } }, { "isoform_ac": "A0A8V0XJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ64/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISWPSCHLYCECKNARRKIVIINFFQSCIWIL", "length": 306, "header": "tr|A0A8V0XJ64-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102586698, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009926.1", "url": "https://www.ensembl.org/id/ENSGALT00010009926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005809.1", "url": "https://www.ensembl.org/id/ENSGALP00010005809.1" } ] } }, { "isoform_ac": "A0A8V0XJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ78/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLVRSTQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISCLVISGVGEALLVYTERTGT", "length": 274, "header": "tr|A0A8V0XJ78-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102583579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009941.1", "url": "https://www.ensembl.org/id/ENSGALT00010009941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005824.1", "url": "https://www.ensembl.org/id/ENSGALP00010005824.1" } ] } }, { "isoform_ac": "A0A8V0XM14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM14/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLVRSTQPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISWLFLGITFRNATGKCTAFKARNFAAKK", "length": 308, "header": "tr|A0A8V0XM14-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102559725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009947.1", "url": "https://www.ensembl.org/id/ENSGALT00010009947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005830.1", "url": "https://www.ensembl.org/id/ENSGALP00010005830.1" } ] } }, { "isoform_ac": "A0A8V0XNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNM9/entry", "sequence": { "sequence": "MADVSWWTSASCLLEVGLGGDKLVFKYCQMREILTITVASTRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKVITASLSPFFFAMTANVLTISCLVISGVGEALLVYTERTGT", "length": 272, "header": "tr|A0A8V0XNM9-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102632506, "end_pos": 102583579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009930.1", "url": "https://www.ensembl.org/id/ENSGALT00010009930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005813.1", "url": "https://www.ensembl.org/id/ENSGALP00010005813.1" } ] } }, { "isoform_ac": "A0A8V0XNP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP9/entry", "sequence": { "sequence": "MYLKRPAGGLAFCLFYLASCFTNKYVLSVLKFTYPTLFQGWQTLVGGLLLHVSWKLGWVEISLCSRSEILSWLPASVIFVGIIYAGSRALSRLPIPVFLTIHNAAEVITCGFQKFVQKEQISHLKVCSVLFLLVAAVCLPLCDTQFDPNGYLWALIHLICVGAYKVFHKLWKPNSLSDLDQQYINYVFSVVLLASASHPAGDLFSALDFPFLYFYRFHSSCCASGLLGFFLMLHTVKLKSSTTLGQYAAWSFLAKMTISCVLLMLTQTCWEFFVIPQGCS", "length": 280, "header": "tr|A0A8V0XNP9-1|A0A3Q2TWK9_CHICK Computationally mapped isoform of Transmembrane protein 241 OS=Gallus gallus OX=9031 GN=TMEM241 PE=4 SV=1 CANONICAL=A0A3Q2TWK9-1" }, "locus": { "chromosome": "2", "start_pos": 102636100, "end_pos": 102564230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009945.1", "url": "https://www.ensembl.org/id/ENSGALT00010009945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005828.1", "url": "https://www.ensembl.org/id/ENSGALP00010005828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UDP-N-acetylglucosamine transmembrane transporter activity", "id": "GO:0005462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005462", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TWK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TWK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWK9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TWK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWK9" }, { "id": "PF03151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sugar phosphate transporter", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 193, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RR59-1", "uniprot_ac": "A0A1L1RR59", "uniprot_id": "A0A1L1RR59_CHICK", "mass": { "chemical_mass": 52643.0, "monoisotopic_mass": 52643.0 }, "refseq": { "ac": "XP_015138801", "name": "coiled-coil domain-containing protein 85A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138801" }, "gene_names": [ { "name": "CCDC85A", "type": "recommended", "evidence": [ { "id": "A0A1L1RR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59" } ] }, { "name": "CCDC85A", "type": "synonym", "evidence": [ { "id": "XP_015138801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138801" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 85A", "type": "synonym", "evidence": [ { "id": "A0A1L1RR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 85A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138801" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138801" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RR59", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC85A", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59", "locus": { "chromosome": "3", "start_pos": 539309, "end_pos": 475712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018897", "url": "https://www.ensembl.org/id/ENSGALG00010018897" } ] } } ], "crossref": [ { "id": "A0A1L1RR59", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RR59", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043080", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043080", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421205", "url": "https://www.ncbi.nlm.nih.gov/gene/421205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421205", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421205", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGNVCSP", "url": "https://omabrowser.org/oma/group/DGNVCSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RJ65", "url": "https://www.orthodb.org/?gene=A0A1L1RJ65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RR59", "url": "https://www.orthodb.org/?gene=A0A1L1RR59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13546:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13546:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RJ65", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RJ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RR59", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RR59-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKVAAESCGTAPAEDLSKVSDEELLQWSKEELIRSLRRAEAEKMSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYSASVMHKEVALYLQKLKELEVRQEEVVKENLELKELCVLLDEEKGGGAGSRSSIDSQISLCQLTATSTYMRDVGDGSSTSSTGSTDSPDHHKHHPSTSPEHLQKARGEGSPEHQKHRSISPEHLQKPRSSGSPDHHLKGPSPEHQKTIVKTPEQQKHSSSSPETLPKHVLSSSPEHFQKQRPGSSPEHQKHSSGSPDHLQKHTPSGSTEHLHKVRGTSPEHLKKHYGGSPEHLKHLSAGSREGTLRRQVTDDLSPHHRSIYNGMNESTLSYVRQLEARVRQLEEENRVLPQDPLRMPGGSEGSYCSANEPASISGHGSASQQSESVVNALKVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 473, "header": "tr|A0A1L1RR59-1|A0A1L1RR59_CHICK Isoform 1 of Coiled-coil domain containing 85A OS=Gallus gallus OX=9031 GN=CCDC85A PE=3 SV=2 CANONICAL=A0A1L1RR59-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RJ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ65/entry", "sequence": { "sequence": "MAKVAAESCGTAPAEDLSKVSDEELLQWSKEELIRSLRRAEAEKMSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYSASVMHKEVALYLQKLKELEVRQEEVVKENLELKELCVLLDEEKGGGAGSRSSIDSQISLCQLTATSTYMRDVGDGSSTSSTGSTDSPDHHKHHPSTSPEHLQKARGEGSPEHQKHRSISPEHLQKPRSSGSPDHHLKGPSPEHQKTIVKTPEQQKHSSSSPETLPKHVLSSSPEHFQKQRPGSSPEHQKHSSGSPDHLQKHTPSGSTEHLHKVRGTSPEHLKKHYGGSPEHLKHLSAGSREGTLRRQVTDDLSPHHRSIYNGMNESTLSYVRQLEARVRQLEEENRVLPQVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 433, "header": "tr|A0A1L1RJ65-1|A0A1L1RR59_CHICK Computationally mapped isoform of Coiled-coil domain containing 85A OS=Gallus gallus OX=9031 GN=CCDC85A PE=3 SV=2 CANONICAL=A0A1L1RR59-1" }, "locus": { "chromosome": "3", "start_pos": 537363, "end_pos": 475971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045686.1", "url": "https://www.ensembl.org/id/ENSGALT00010045686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027236.1", "url": "https://www.ensembl.org/id/ENSGALP00010027236.1" } ] } }, { "isoform_ac": "A0A1L1RR59-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59/entry", "sequence": { "sequence": "MAKVAAESCGTAPAEDLSKVSDEELLQWSKEELIRSLRRAEAEKMSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYSASVMHKEVALYLQKLKELEVRQEEVVKENLELKELCVLLDEEKGGGAGSRSSIDSQISLCQLTATSTYMRDVGDGSSTSSTGSTDSPDHHKHHPSTSPEHLQKARGEGSPEHQKHRSISPEHLQKPRSSGSPDHHLKGPSPEHQKTIVKTPEQQKHSSSSPETLPKHVLSSSPEHFQKQRPGSSPEHQKHSSGSPDHLQKHTPSGSTEHLHKVRGTSPEHLKKHYGGSPEHLKHLSAGSREGTLRRQVTDDLSPHHRSIYNGMNESTLSYVRQLEARVRQLEEENRVLPQDPLRMPGGSEGSYCSANEPASISGHGSASQQSESVVNALKVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 473, "header": "tr|A0A1L1RR59-1|A0A1L1RR59_CHICK Isoform 1 of Coiled-coil domain containing 85A OS=Gallus gallus OX=9031 GN=CCDC85A PE=3 SV=2 CANONICAL=A0A1L1RR59-1" }, "locus": { "chromosome": "3", "start_pos": 537363, "end_pos": 475971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045682.1", "url": "https://www.ensembl.org/id/ENSGALT00010045682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027235.1", "url": "https://www.ensembl.org/id/ENSGALP00010027235.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421205", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421205", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LS67-1", "protein_name": "Coiled-coil domain containing 85A", "gene_name": "Ccdc85a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKAAGGAAPAAESCPSAPAGVSTPAGVEDLSKVTDEELLQWSKEDLIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVVKENMELKELCVLLDEEKGTGCAGSRCSIDSQASLCQLVASAAPYVRDVGDGSSTSSTGSTDSPDHHKHHASGGSPEHLQKPRSEGSPEHNKHRSTSPEHLHKPRASGTPDHPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPEMLPKHKLSGSPEHFQKHRPGGSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHAGGGGGSGGGSREGTLRRPAQEDSSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQATQNRSQPPTRNSSNMEKGWGPRARRVLQWWQGCRGIGRCLPSLPGSFRLSSGADGNNSSPNSPASFSGHTTPSQQPEPVVHSLKVLDVEETVDRQQGKEYDHDLSETEKAIVREMCNVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 578 }, "evidence": [ { "id": "A0A1L1RR59", "url": "https://omabrowser.org/oma/group/A0A1L1RR59/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SP85-1", "protein_name": "Coiled-coil domain-containing protein 85A", "gene_name": "Ccdc85a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKAAGGSAPAAESCPSAPAGASTPTGVDDLSKVTDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVVKENMELKELCMLLDEEKGVGCAGSRCSIDSQASLCQLVASATPYVRDVGDGSSTSSTGSTDSPDHHKHHASGGSPEHLQKPRSEGSPEHTKHRSTSPEHLHKPRASGTPDHSKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPEVLPKHVLSGSPEHFQKHRPGGSPEHTRHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGASPDHKHASGSGGSGGGSREGTLRRPAQEDSSSHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQGSFRLSSGADGNNSSLNSPASFSGHTTPSQQPEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 500 }, "evidence": [ { "id": "A0A1L1RR59", "url": "https://omabrowser.org/oma/group/A0A1L1RR59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PX6-1", "protein_name": "Coiled-coil domain-containing protein 85A", "gene_name": "CCDC85A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "length": 553 }, "evidence": [ { "id": "A0A1L1RR59", "url": "https://omabrowser.org/oma/group/A0A1L1RR59/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RR59", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RR59" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RR59-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RR59-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RR59" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U027-1", "uniprot_ac": "A0A3Q2U027", "uniprot_id": "A0A3Q2U027_CHICK", "mass": { "chemical_mass": 40346.0, "monoisotopic_mass": 40346.0 }, "refseq": { "ac": "NP_001156810", "name": "muscleblind-like protein 3 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810" }, "gene_names": [ { "name": "MBNL3", "type": "recommended", "evidence": [ { "id": "A0A3Q2U027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ] }, { "name": "MBNL3", "type": "synonym", "evidence": [ { "id": "NP_001156810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810" } ] } ], "protein_names": [ { "name": "Muscleblind like splicing regulator 3", "type": "synonym", "evidence": [ { "id": "A0A3Q2U027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027/entry#names_and_taxonomy" } ] }, { "name": "muscleblind-like 3", "type": "synonym", "evidence": [ { "id": "NP_001156810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810" } ] }, { "name": "muscleblind-like protein 3 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001156810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2368565.384305.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001156810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MBNL3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027", "locus": { "chromosome": "4", "start_pos": 3446226, "end_pos": 3535183, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017338", "url": "https://www.ensembl.org/id/ENSGALG00010017338" } ] } } ], "crossref": [ { "id": "A0A3Q2U027", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U027", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000053597", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000053597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422233", "url": "https://www.ncbi.nlm.nih.gov/gene/422233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEMAMID", "url": "https://omabrowser.org/oma/group/LEMAMID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RMI2", "url": "https://www.orthodb.org/?gene=A0A1L1RMI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U027", "url": "https://www.orthodb.org/?gene=A0A3Q2U027", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAN5", "url": "https://www.orthodb.org/?gene=A0A3Q2UAN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTV9", "url": "https://www.orthodb.org/?gene=A0A8V0YTV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0U6", "url": "https://www.orthodb.org/?gene=A0A8V0Z0U6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z260", "url": "https://www.orthodb.org/?gene=A0A8V0Z260", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7Q4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7U5", "url": "https://www.orthodb.org/?gene=A0A8V0Z7U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12675:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001156810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RMI2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RMI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RMI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RMI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U027-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0U6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z260", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z260", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z260-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z260-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTGSVLCMTPTASVVPMMHGATPTTVSAATTPATSVPFAATATANQISQLSVDELSSSMFVSQM", "length": 371, "header": "tr|A0A3Q2U027-1|A0A3Q2U027_CHICK Isoform 1 of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RMI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RMI2/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTVPMMHGATPTTVSAATTPATSVPFAATATANQISQLSVDELSSSMFVSQM", "length": 359, "header": "tr|A0A1L1RMI2-1|A0A3Q2U027_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=2 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3456284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041934.1", "url": "https://www.ensembl.org/id/ENSGALT00010041934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024538.1", "url": "https://www.ensembl.org/id/ENSGALP00010024538.1" } ] } }, { "isoform_ac": "A0A3Q2U027-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTGSVLCMTPTASVVPMMHGATPTTVSAATTPATSVPFAATATANQISQLSVDELSSSMFVSQM", "length": 371, "header": "tr|A0A3Q2U027-1|A0A3Q2U027_CHICK Isoform 1 of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3456284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041938.1", "url": "https://www.ensembl.org/id/ENSGALT00010041938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024542.1", "url": "https://www.ensembl.org/id/ENSGALP00010024542.1" } ] } }, { "isoform_ac": "A0A3Q2UAN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAN5/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALANMQLQQPTFIPTDIPVISR", "length": 281, "header": "tr|A0A3Q2UAN5-1|A0A3Q2UAN5_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=3 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3456318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041947.1", "url": "https://www.ensembl.org/id/ENSGALT00010041947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024549.1", "url": "https://www.ensembl.org/id/ENSGALP00010024549.1" } ] } }, { "isoform_ac": "A0A8V0YTV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV9/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPIVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTGSVLCMTPTASVVPMMHGATPTTVSAATTPATSVPFAATATANQVWPFQWLSFTCVQISRTGRGLPVPPGSVQARARRGSVCLGIGEGAPAGTAAAGA", "length": 340, "header": "tr|A0A8V0YTV9-1|A0A3Q2U027_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3457568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041846.1", "url": "https://www.ensembl.org/id/ENSGALT00010041846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024474.1", "url": "https://www.ensembl.org/id/ENSGALP00010024474.1" } ] } }, { "isoform_ac": "A0A8V0Z0U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0U6/entry", "sequence": { "sequence": "MQPWQYLTWHMLLGPQMSFSNVTQWSECHRGSGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTVPMMHGATPTTVSAATTPATSVPFAATATANQISQLSVDELSSSMFVSQM", "length": 333, "header": "tr|A0A8V0Z0U6-1|A0A3Q2U027_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3510214, "end_pos": 3456284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041930.1", "url": "https://www.ensembl.org/id/ENSGALT00010041930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024534.1", "url": "https://www.ensembl.org/id/ENSGALP00010024534.1" } ] } }, { "isoform_ac": "A0A8V0Z260-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z260/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMVSGALINMKH", "length": 269, "header": "tr|A0A8V0Z260-1|A0A3Q2U027_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3469915, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041920.1", "url": "https://www.ensembl.org/id/ENSGALT00010041920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024528.1", "url": "https://www.ensembl.org/id/ENSGALP00010024528.1" } ] } }, { "isoform_ac": "A0A8V0Z7Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q4/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTADHVEILNRKITEHQDFLVGSCAWPFCIYPLFPSLVLYHLYSKPVAAYMLTKN", "length": 362, "header": "tr|A0A8V0Z7Q4-1|A0A8V0Z7Q4_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3453682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041860.1", "url": "https://www.ensembl.org/id/ENSGALT00010041860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024485.1", "url": "https://www.ensembl.org/id/ENSGALP00010024485.1" } ] } }, { "isoform_ac": "A0A8V0Z7U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U5/entry", "sequence": { "sequence": "MAVNVSLVRDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQFMLPGTQLQPITTFPVTPSLATSPTMAFSPYLSHVSPGMGLVPAELLPNTPVLVSGNPTVTVPGSSAGQKLMRTDKLEVCREFQRGNCTRGENDCRYAHPIDIAMIDTNENTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQHQVNQTAAAAMALPPGALQPLPKRPALEKNNGATTVFNPSVFHYQQALANMQLQQPTFIPTGKCLLAFSIVVFFV", "length": 323, "header": "tr|A0A8V0Z7U5-1|A0A8V0Z7U5_CHICK Computationally mapped isoform of Muscleblind like splicing regulator 3 OS=Gallus gallus OX=9031 GN=MBNL3 PE=1 SV=1 CANONICAL=A0A3Q2U027-1" }, "locus": { "chromosome": "4", "start_pos": 3504730, "end_pos": 3462221, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041926.1", "url": "https://www.ensembl.org/id/ENSGALT00010041926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024531.1", "url": "https://www.ensembl.org/id/ENSGALP00010024531.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 119, "start_aa": "Thr", "end_pos": 119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr119", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3AGP9-1", "protein_name": "Muscleblind-like protein 3 isoform X1", "gene_name": "mbnl3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVNVTMGRDTKWLTLEVCREFQRGTCSRSDSECKFAHPSRTCHVENGRVIACFDSLKGRCTRDNCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMLPGAQLQPITSFPVTPSLANSPSMAFSPYLSHVSPGISLMPELLPSAPVLVPGSPTGITMGNGNSTQKHVRTDKLEVCREFQRGNCTRGENDCRYAHPMEAAMVDGSENSVIVCMDYIKGRCTRDKCKYFHPPAHLQARIKAAQHQASQNAAAMALPPGAMQQLPKRPTLEKSNGAAAVFNPSMFHYQQALASMQLQQPAFIPTGSVFCMAPSGGIGLFKPPGPMTEGRWERRDWTGCRAPQSRYLSGPGHTVPMMHGATTSTVSSATTPVTNVPFAESATSNQTPPRY", "length": 393 }, "evidence": [ { "id": "A0A3Q2U027", "url": "https://omabrowser.org/oma/group/A0A3Q2U027/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U027", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U027-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 371, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U027-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U027" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U027" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 41, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 119 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RQ93-1", "uniprot_ac": "A0A1L1RQ93", "uniprot_id": "A0A1L1RQ93_CHICK", "mass": { "chemical_mass": 68154.0, "monoisotopic_mass": 68154.0 }, "refseq": { "ac": "XP_015155348", "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155348" }, "gene_names": [ { "name": "LINGO3", "type": "recommended", "evidence": [ { "id": "A0A1L1RQ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93" } ] }, { "name": "LINGO3", "type": "synonym", "evidence": [ { "id": "XP_015155348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155348" } ] } ], "protein_names": [ { "name": "Leucine rich repeat and Ig domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A1L1RQ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "type": "synonym", "evidence": [ { "id": "XP_015155348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155348" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155348" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQ93", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LINGO3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93", "locus": { "chromosome": "28", "start_pos": 2410638, "end_pos": 2386037, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028495", "url": "https://www.ensembl.org/id/ENSGALG00010028495" } ] } } ], "crossref": [ { "id": "ENSGALG00000000806", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420075", "url": "https://www.ncbi.nlm.nih.gov/gene/420075", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420075", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420075", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFTMKMI", "url": "https://omabrowser.org/oma/group/KFTMKMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RQ93", "url": "https://www.orthodb.org/?gene=A0A1L1RQ93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13306", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13306", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155348", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RQ93", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYTMTCWLPVLVLHLVLLSPLQVAACPARCECAPQIKSVVCHRKRLTAIPEGIPTETKILELNKNRIRCLNPGDLSPYPLLEELDFSENIITNVEPGAFSNLFNLQTLRLRGNQLKLIPPGVFTKLTNLTLLDISENKLVILLDYMFQDLRNLKSLEVGDNDLVYISQRAFSGLLGLEQLTIEKCNLTSISAESLSYLQNLEVLRLRHLSISALEEQNFKKLYNLLQLEIDNWPLLEDISPTSFQGLNLTSLSITYTNITAVPTAALRNLVYLRYLNLSYNPISTVLKGSFKDLIRLQELHIVGALLVSVEPQAFSGLRQIRLLNLSSNFLSTLEESTFHSVNTLETLRVDRNPLACDCRLLWILQRRKTLNFDGQQPMCSTPPEIQGNALRDFPDSVLFEYFTCQKPKIRDRKLQHVTAREGQSVSFLCRADGEPEPSIVWVSPQHRMITTRSTGRATVLPGGTLEIRFAQVQDSGTYICIASNAGGNDTYFATLTVKGHPNDGSSNANRTLYLNEFNDTYHNDTQVFLKFTLDLKTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPTTTTGQGGARKFNMKMI", "length": 605, "header": "tr|A0A1L1RQ93-1|A0A1L1RQ93_CHICK Isoform 1 of Leucine rich repeat and Ig domain containing 3 OS=Gallus gallus OX=9031 GN=LINGO3 PE=4 SV=1 CANONICAL=A0A1L1RQ93-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQ93/entry", "sequence": { "sequence": "MLYTMTCWLPVLVLHLVLLSPLQVAACPARCECAPQIKSVVCHRKRLTAIPEGIPTETKILELNKNRIRCLNPGDLSPYPLLEELDFSENIITNVEPGAFSNLFNLQTLRLRGNQLKLIPPGVFTKLTNLTLLDISENKLVILLDYMFQDLRNLKSLEVGDNDLVYISQRAFSGLLGLEQLTIEKCNLTSISAESLSYLQNLEVLRLRHLSISALEEQNFKKLYNLLQLEIDNWPLLEDISPTSFQGLNLTSLSITYTNITAVPTAALRNLVYLRYLNLSYNPISTVLKGSFKDLIRLQELHIVGALLVSVEPQAFSGLRQIRLLNLSSNFLSTLEESTFHSVNTLETLRVDRNPLACDCRLLWILQRRKTLNFDGQQPMCSTPPEIQGNALRDFPDSVLFEYFTCQKPKIRDRKLQHVTAREGQSVSFLCRADGEPEPSIVWVSPQHRMITTRSTGRATVLPGGTLEIRFAQVQDSGTYICIASNAGGNDTYFATLTVKGHPNDGSSNANRTLYLNEFNDTYHNDTQVFLKFTLDLKTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPTTTTGQGGARKFNMKMI", "length": 605, "header": "tr|A0A1L1RQ93-1|A0A1L1RQ93_CHICK Isoform 1 of Leucine rich repeat and Ig domain containing 3 OS=Gallus gallus OX=9031 GN=LINGO3 PE=4 SV=1 CANONICAL=A0A1L1RQ93-1" }, "locus": { "chromosome": "28", "start_pos": 2407391, "end_pos": 2405577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068998.1", "url": "https://www.ensembl.org/id/ENSGALT00010068998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042440.1", "url": "https://www.ensembl.org/id/ENSGALP00010042440.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420075", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M4X1-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "Lingo3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCWLHMLGLHLLLLPTAPLATGCPARCECSASTRTVACGRRRLTAVPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLEVGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKLPGLLHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVPRGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALHNLPDSVLFEYFVCRKPKIRERRLQHVTATEGDDVRFLCRAEGEPAPTVAWVTPQHHSVTAASRGRARVLPGGTLAITDTRPQDSGTYTCVASNAGGNDTYFATLTIHPAANRTQSDGHNETQVGVRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 589 }, "evidence": [ { "id": "A0A1L1RQ93", "url": "https://omabrowser.org/oma/group/A0A1L1RQ93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N3H2-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "LINGO3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCWLWVLSLQFLLLPAALPPAGGCPARCECTAQTRAVACPRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPLLEELDLSENVIAHVEPGAFANLPRLRVLRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPSAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWVVQRRKTLNFDGRPPACATPAEVRGDALRSLPDSALFEYFVCRKPKIRERRLQRITAAAGADVRFQCRAEGEPAPTVAWVTPRHRTVTAASAGRARVLPGGTLHIQDARPGDSGTYTCVASNAGGNDTYFATLSVQPEPAVNRTPGEGRNDTQVAARFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 592 }, "evidence": [ { "id": "A0A1L1RQ93", "url": "https://omabrowser.org/oma/group/A0A1L1RQ93/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S8I1-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "LINGO3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTCWLCVLSLQLLLLPAAPPPAGGCPARCECTAQTRAVACPRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPLLEELDLSDNVIAHVEPGAFANLPRLRELRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQHVTAAAGDDVRFQCRAEGEPAPTVAWVTPRHRAVTATSAGRARVLPGGTLQIRDAQPGDSGTYTCVASNAGGNDTYFATLSVQPEPATNRTLGEGRNDTQAAMRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQSGARKFNMKMI", "length": 592 }, "evidence": [ { "id": "A0A1L1RQ93", "url": "https://omabrowser.org/oma/group/A0A1L1RQ93/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C6S8-1", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "gene_name": "LINGO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTCWLCVLSLPLLLLPAAPPPAGGCPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPALEELDLSENAIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLHSLRRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLRSLGALRLRHLAIASLEDQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQRVTATAGEDVRFLCRAEGEPAPTVAWVTPQHRPVTATSAGRARVLPGGTLEIQDARPQDSGTYTCVASNAGGNDTYFATLTVRPEPAANRTPGEAHNETLAALRAPLDLTTILVSTAMGCITFLGVVLFCFVLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 592 }, "evidence": [ { "id": "A0A1L1RQ93", "url": "https://omabrowser.org/oma/group/A0A1L1RQ93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6GQU6-1", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "gene_name": "Lingo3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTCWLHMLGLHLLLLPTAPLAAGCPARCECSASTRTVACGRRRLTAIPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLEVGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKLPGLSHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVPRGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALHNLPDSVLFEYFVCRKPKIRERRLQHVTATEGDDVRFLCRAEGEPAPTVAWVTPQHHSVTAASRGRARVLPGGTLTIADTRPQDSGTYTCVASNAGGNDTYFATLTVQPAANRTQGDGHNETQVGVRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 589 }, "evidence": [ { "id": "A0A1L1RQ93", "url": "https://omabrowser.org/oma/group/A0A1L1RQ93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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"Protein" ] }, { "id": "A0A8V0X4W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNRAVSRLSRKRPPSEINDSEGHPSSSRQSLKGTSEWATSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEEFKKTQGKKQMREKAKEIYMTFLSNKASSQVNVEGQSRLNETILETPHPLMFQKLQDQIFNLMKYDSYSRFLKSDIFLNHKKSEEQEENSSEAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A1L1RQE4-1|A0A1L1RQE4_CHICK Isoform 1 of Regulator of G protein signaling 10 OS=Gallus gallus OX=9031 GN=RGS10 PE=1 SV=1 CANONICAL=A0A1L1RQE4-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RQE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4/entry", "sequence": { "sequence": "MFNRAVSRLSRKRPPSEINDSEGHPSSSRQSLKGTSEWATSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEEFKKTQGKKQMREKAKEIYMTFLSNKASSQVNVEGQSRLNETILETPHPLMFQKLQDQIFNLMKYDSYSRFLKSDIFLNHKKSEEQEENSSEAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A1L1RQE4-1|A0A1L1RQE4_CHICK Isoform 1 of Regulator of G protein signaling 10 OS=Gallus gallus OX=9031 GN=RGS10 PE=1 SV=1 CANONICAL=A0A1L1RQE4-1" }, "locus": { "chromosome": "6", "start_pos": 31020244, "end_pos": 31006214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005156.1", "url": "https://www.ensembl.org/id/ENSGALT00010005156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003032.1", "url": "https://www.ensembl.org/id/ENSGALP00010003032.1" } ] } }, { "isoform_ac": "A0A8V0X4W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4W8/entry", "sequence": { "sequence": "MFNRAVSRLSRKRPPSAEINDSEGHPSSSRQSLKGTSEWATSLENLLEDPEGVKRFRFLKKEFSEENVLFWLACEEFKKTQGKKQMREKAKEIYMTFLSNKASSQVNVEGQSRLNETILETPHPLMFQKLQDQIFNLMKYDSYSRFLKSDIFLNHKKSEEQEENSSEAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A8V0X4W8-1|A0A1L1RQE4_CHICK Computationally mapped isoform of Regulator of G protein signaling 10 OS=Gallus gallus OX=9031 GN=RGS10 PE=1 SV=1 CANONICAL=A0A1L1RQE4-1" }, "locus": { "chromosome": "6", "start_pos": 31020244, "end_pos": 31006214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005154.1", "url": "https://www.ensembl.org/id/ENSGALT00010005154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003031.1", "url": "https://www.ensembl.org/id/ENSGALP00010003031.1" } ] } }, { "isoform_ac": "A0A8V0XEJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEJ3/entry", "sequence": { "sequence": "MVLFSIFPEINDSEGHPSSSRQSLKGTSEWATSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEEFKKTQGKKQMREKAKEIYMTFLSNKASSQVNVEGQSRLNETILETPHPLMFQKLQDQIFNLMKYDSYSRFLKSDIFLNHKKSEEQEENSSEAQTAAKRASRIYNT", "length": 173, "header": "tr|A0A8V0XEJ3-1|A0A1L1RQE4_CHICK Computationally mapped isoform of Regulator of G protein signaling 10 OS=Gallus gallus OX=9031 GN=RGS10 PE=1 SV=1 CANONICAL=A0A1L1RQE4-1" }, "locus": { "chromosome": "6", "start_pos": 31015339, "end_pos": 31006214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005151.1", "url": "https://www.ensembl.org/id/ENSGALT00010005151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003029.1", "url": "https://www.ensembl.org/id/ENSGALP00010003029.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SUG4-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSASSSHQNPKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEDSTDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A1L1RQE4", "url": "https://omabrowser.org/oma/group/A0A1L1RQE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43665-3", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A1L1RQE4", "url": "https://omabrowser.org/oma/group/A0A1L1RQE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49806-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "Rgs10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDGDGSSSSGHQSLKSTAKWASSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTEDKKQMQEKAKKIYMTFLSNKASSQVNVEGQSRLTEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHRRTEEEEEDPPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A1L1RQE4", "url": "https://omabrowser.org/oma/group/A0A1L1RQE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHW7-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFNRAVSRLSRKRPPSDIHDSDGSSSSSHQTPKSTAKWASSLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKTQDKKQMQEKAKEIYMTFLSSKASSQVNVEGQSRLNEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEDEESPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A1L1RQE4", "url": "https://omabrowser.org/oma/group/A0A1L1RQE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQE5-1", "protein_name": "Regulator of G protein signaling 10", "gene_name": "Rgs10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDGDGSSSSGHQSLKSTAKWASSLENLLEDPEGVQRFREFLKKEFSEENVLFWLACEDFKKTEDRKQMQEKAKEIYMTFLSNKASSQVNVEGQSRLTEKILEEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKPKRTEEEEEEPPDAQTAAKRASRIYNT", "length": 181 }, "evidence": [ { "id": "A0A1L1RQE4", "url": "https://omabrowser.org/oma/group/A0A1L1RQE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" }, { "name": "G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007213", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQE4", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RQX0-1", "uniprot_ac": "A0A1L1RQX0", "uniprot_id": "A0A1L1RQX0_CHICK", "mass": { "chemical_mass": 42279.0, "monoisotopic_mass": 42279.0 }, "refseq": { "ac": "XP_424044", "name": "coiled-coil domain-containing protein 89", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424044" }, "gene_names": [ { "name": "CCDC89", "type": "recommended", "evidence": [ { "id": "A0A1L1RQX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0" } ] }, { "name": "CCDC89", "type": "synonym", "evidence": [ { "id": "XP_424044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424044" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 89", "type": "recommended", "evidence": [ { "id": "A0A1L1RQX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 89", "type": "synonym", "evidence": [ { "id": "XP_424044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424044" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_424044.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RQX0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC89", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0", "locus": { "chromosome": "1", "start_pos": 190165450, "end_pos": 190167793, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008102", "url": "https://www.ensembl.org/id/ENSGALG00010008102" } ] } } ], "crossref": [ { "id": "A0A1L1RQX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RQX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037520", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426393", "url": "https://www.ncbi.nlm.nih.gov/gene/426393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426393", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMLCSRI", "url": "https://omabrowser.org/oma/group/AMLCSRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RQX0", "url": "https://www.orthodb.org/?gene=A0A1L1RQX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34768:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34768:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RQX0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RQX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAACFGRNQSSSSGSVSMAHEDGEAVVANHTSDAEMGKDTEDPTKGTQTLCGSPEEKREKALLRARLEEQHRLICILKKKTDDARKRCKSLEQLNMELEKLRLEDAVKLKTQTQRIQYLEDLANNQEKMIYSKDEQEKQNTQLKEENQRLQQENKTLFSQAAKDNEAEMLQLAAQARELLQQLDTLHEKCAWERSRAQQLEKELLEAQSQQAHACTLEVDSLRQQLQRLQEEHQQMVEQLEHGESQQKAHDAELQAKLERANEEKEQLLNLAAERGKALQEKQQEILQLGRKLEMAERAKWRAEKHIVKEVAANYGLKVQELQQELKSSQQAYSKLSLQFDAYKKHSMDLLSKEKALNVKLRHFKA", "length": 366, "header": "tr|A0A1L1RQX0-1|A0A1L1RQX0_CHICK Isoform 1 of Coiled-coil domain-containing protein 89 OS=Gallus gallus OX=9031 GN=CCDC89 PE=3 SV=2 CANONICAL=A0A1L1RQX0-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RQX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RQX0/entry", "sequence": { "sequence": "MAACFGRNQSSSSGSVSMAHEDGEAVVANHTSDAEMGKDTEDPTKGTQTLCGSPEEKREKALLRARLEEQHRLICILKKKTDDARKRCKSLEQLNMELEKLRLEDAVKLKTQTQRIQYLEDLANNQEKMIYSKDEQEKQNTQLKEENQRLQQENKTLFSQAAKDNEAEMLQLAAQARELLQQLDTLHEKCAWERSRAQQLEKELLEAQSQQAHACTLEVDSLRQQLQRLQEEHQQMVEQLEHGESQQKAHDAELQAKLERANEEKEQLLNLAAERGKALQEKQQEILQLGRKLEMAERAKWRAEKHIVKEVAANYGLKVQELQQELKSSQQAYSKLSLQFDAYKKHSMDLLSKEKALNVKLRHFKA", "length": 366, "header": "tr|A0A1L1RQX0-1|A0A1L1RQX0_CHICK Isoform 1 of Coiled-coil domain-containing protein 89 OS=Gallus gallus OX=9031 GN=CCDC89 PE=3 SV=2 CANONICAL=A0A1L1RQX0-1" }, "locus": { "chromosome": "1", "start_pos": 190167673, "end_pos": 190165579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019325.1", "url": "https://www.ensembl.org/id/ENSGALT00010019325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010873.1", "url": "https://www.ensembl.org/id/ENSGALP00010010873.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426393", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IGN7-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "Ccdc89", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPQDEQTLRMDNPTPDESLGKQNENLQNQDEELGFKEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNNELEEKRMQEIEKMKVQSDHVQKLEDRFMTLAANHEMMIRFKDEHKNANLKLKEENEKLKQENSNLFSQALKDQEAKILQLTANNKALVEELEVLKLRCAHDTSQAQAREKELLGLQTQQACAHAKETEQLLSQLQSLKQLHRQATNKMAKDQEEHSSLSQDLQTRLQTVTREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNAKLRHLFP", "length": 370 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RZ86-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "Ccdc89", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQKEKTLRMDTPPPDEILGRQNENLENEDDELGFKEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEKRMQEMEKMKVQNEQVQKLESRFMTLAANHELMIRFKDEHKSENIKLKEENEKLRQENNSLFSQALKDQENKVLQLTAHNKALVEELEVLKQRCAHEAGQARAREEELLALQNQQACEHAKETEQLRSQLQSIKQQHRQATEQMGKDQEANINMNQELQARLHTVMREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRKVDGIQKAYDDLRLQSEAFKKHSLDLLSKERELNAKLRHLFP", "length": 370 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1STT3-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "CCDC89", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPQEETALGMDAPSAEKLLEKQNKKLENQEEEGLEFKELDGLREALANLRGLSEEEKGEKAMLCSRIQEQSQLICILKRRSDEALERCQVLELLNAELEEKRMLEAEKLKAKSEHAEKLEERFMTLAANHELMIRFKDEHKNQNIKLREENEKLRLENDHLFSQALKDQEVKVAQLTAQSEALAKELETLKQRSAQDACQAQAREKELLKLQSQQACAHARETEQLRSQLQSLKQQHQQATEQMAKAEQAHSLLNQELQARLQTVSREKEELLQLSMERGKVLQNKQAEIRQLEDKLETADVARRHAVERFEQEAVAVDSNLRVRELQRRVDGIQKAYDELRLQSEAFKRHSLDLLSKERELNAKLRHLFP", "length": 371 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q29RS0-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "CCDC89", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPQEESAPRMDTPSSEEPLDKQNRKLEDQEEEMGFKELDGLREALANLRGLSEEDKSERAMLCSRIQEQSQLICILKRRSDEALERCQTLELLNTELEEKRLLEAEELKAKNQQAQKLEERFMTLASNHELMIRFKDEHKRQNAKLREENEKLRLENDQLFSPALKAQEAKVVQLTAQSEALAKELETLQRKYAHDVCQAQAREQELLELQNRQACAHTEETEQLRMQLQSLQQQQQEALQQTAKAEQAHSQQNQELRARLQTVTREKEELLLLSMERGRVLQNKQAEIRQLEEKLKMADVARRHALERFEQEAVAVNSNLRVRELQRRVDGIQAAYDELRLQSEAFKKHSLDLLSKERELNAKLRHLFP", "length": 370 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8N998-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "CCDC89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAPMLQKQQAPRMDTPPPEERLEKQNEKLNNQEEETEFKELDGLREALANLRGLSEEERSEKAMLRSRIEEQSQLICILKRRSDEALERCQILELLNAELEEKMMQEAEKLKAQGEYSRKLEERFMTLAANHELMLRFKDEYKSENIKLREENEKLRLENSSLFSQALKDEEAKVLQLTVRCEALTGELETLKERCAQDACQAQAREKELLELQSQQACTHTKETEQLRSQLQTLKQQHQQAVEQIAKAEETHSSLSQELQARLQTVTREKEELLQLSIERGKVLQNKQAEICQLEEKLEIANEDRKHALERFEQEAVAVDSNLRVRELQRKVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNGKLRHLSP", "length": 374 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DA73-1", "protein_name": "Coiled-coil domain-containing protein 89", "gene_name": "Ccdc89", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQEEKTLRMDTPPPDEILGKQNENLQNQDEELGFKEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEKRLQEMEKLKAQSEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELTTLNKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNAKLRHLFP", "length": 370 }, "evidence": [ { "id": "A0A1L1RQX0", "url": "https://omabrowser.org/oma/group/A0A1L1RQX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RQX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 366, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RQX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RQX0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RS25-1", "uniprot_ac": "A0A1L1RS25", "uniprot_id": "A0A1L1RS25_CHICK", "mass": { "chemical_mass": 32234.0, "monoisotopic_mass": 32234.0 }, "refseq": { "ac": "XP_003640560", "name": "TLR adapter interacting with SLC15A4 on the lysosome", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640560" }, "gene_names": [ { "name": "CXorf21", "type": "recommended", "evidence": [ { "id": "A0A1L1RS25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ] }, { "name": "CXorf21", "type": "synonym", "evidence": [ { "id": "XP_003640560", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640560" } ] } ], "protein_names": [ { "name": "TLR adapter interacting with SLC15A4 on the lysosome", "type": "synonym", "evidence": [ { "id": "XP_003640560", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640560" } ] }, { "name": "TLR adaptor interacting with endolysosomal SLC15A4", "type": "synonym", "evidence": [ { "id": "A0A1L1RS25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640560" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CXorf21", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25", "locus": {} } ], "crossref": [ { "id": "A0A1L1RS25", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RS25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016286", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857674", "url": "https://www.ncbi.nlm.nih.gov/gene/100857674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857674", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFHDSSP", "url": "https://omabrowser.org/oma/group/MFHDSSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RS25", "url": "https://www.orthodb.org/?gene=A0A1L1RS25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14889:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14889:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9860276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003640560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640560", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RS25-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSEGYLYRIAYLCEDSELCTNQAVEEVVYEMRSINCSSRDEAQVKSLLQRCRSAGKCISAVHSRGSKHSRRQKDNLQQSVQNPLPEGQTSPTMDVCEGLVRKDTYLVPSSCKSICKNYNDLHIAGDCVVPISSVATDFTCDSGIGPFLESSEIPPPMESVRVPPSETGRKQAQGFSSCWRVASLVPHQQPLSDSALNDYLEQKLMELYKQYIMDSTVNRASPTQILASELIMTNVDQISTQISRERKMETTKAKDIVISRFLQIASEQIFSEISTPSLHISQYSNTNA", "length": 289, "header": "tr|A0A1L1RS25-1|A0A1L1RS25_CHICK Isoform 1 of TLR adaptor interacting with endolysosomal SLC15A4 OS=Gallus gallus OX=9031 GN=CXorf21 PE=4 SV=1 CANONICAL=A0A1L1RS25-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RS25-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25/entry", "sequence": { "sequence": "MLSEGYLYRIAYLCEDSELCTNQAVEEVVYEMRSINCSSRDEAQVKSLLQRCRSAGKCISAVHSRGSKHSRRQKDNLQQSVQNPLPEGQTSPTMDVCEGLVRKDTYLVPSSCKSICKNYNDLHIAGDCVVPISSVATDFTCDSGIGPFLESSEIPPPMESVRVPPSETGRKQAQGFSSCWRVASLVPHQQPLSDSALNDYLEQKLMELYKQYIMDSTVNRASPTQILASELIMTNVDQISTQISRERKMETTKAKDIVISRFLQIASEQIFSEISTPSLHISQYSNTNA", "length": 289, "header": "tr|A0A1L1RS25-1|A0A1L1RS25_CHICK Isoform 1 of TLR adaptor interacting with endolysosomal SLC15A4 OS=Gallus gallus OX=9031 GN=CXorf21 PE=4 SV=1 CANONICAL=A0A1L1RS25-1" }, "locus": { "chromosome": "1", "start_pos": 115886025, "end_pos": 115885159, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005112.1", "url": "https://www.ensembl.org/id/ENSGALT00010005112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003014.1", "url": "https://www.ensembl.org/id/ENSGALP00010003014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857674", "resource": "KEGG Pathway" }, { "id": "R-GGA-9860276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860276", "resource": "Reactome", "description": "SLC15A4:TASL-dependent IRF5 activation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SG28-1", "protein_name": "TLR adaptor interacting with endolysosomal SLC15A4", "gene_name": "TASL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSEGYLSGLAYRNDIQWSYPSSNEQVAEEKEEEMEATAAASLSYSSVDETQVQNLYVSCKSSGKVISSVYSRESQHSRNPRITVLQTNPNPVYESPNLAAVELYRDTSRETYLVPPSCKSICKNYNDLQIAGGQVMAINSATTDFPSEGSFQYGPLLKSSEIPLSMEDSMFTQPSDLPPTPIQRYSSYWRITSIKEKNSLQMQKPISNAVLNEYLEQKLVELYKQYFMDTGFHDSSPTQILASELIMTNVDQISIQVSIEKNLEISKARDIVINRLLQYGSTEISTPSLHISQYSNVNP", "length": 300 }, "evidence": [ { "id": "A0A1L1RS25", "url": "https://omabrowser.org/oma/group/A0A1L1RS25/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZRK2-1", "protein_name": "TLR adaptor interacting with endolysosomal SLC15A4", "gene_name": "Tasl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSEGYLSGLTYWNDIHWNCASYNEPVAGDQGEETSSVAALSYSSVDETQVQSVYVSCKSSGKFISSVHARASQHSRSQSRTVLQANSNPVFESPTLAAVGICRDVIRETYLVPPSCKSICKNYNDLHIAGGQVMAINSVMADFPSESSFEDGPLLKSSEISLSMEDSISTQFTELPLKPIQRYSSYWRITSIKEKNSLQMQKPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASEFIMTNVDQISLQVSKEKNLDTSKVKDIVISHLLQLVSSEISTPSLHISQYSDITP", "length": 298 }, "evidence": [ { "id": "A0A1L1RS25", "url": "https://omabrowser.org/oma/group/A0A1L1RS25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SPV1-1", "protein_name": "TLR adaptor interacting with endolysosomal SLC15A4", "gene_name": "TASL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSEGYLSGLAYQNDIYWNCTSCNEQVVEEKEETEATAATALYYSPVDKTQVRNLYVSCKSSDKFISSVHSRESHPSRNPMITVLQANPNPVFESPNLATVELYRDPSRETYLVPPSCKSICKNYNDLHIAGGQVMALNSVTTDFASEGSFEHGPLLKSSEIPLTMEDSISTQPSDLPPKPIQRYSSYWRITSVKEKSSLQMQKPISNAVLNEYLEQKVVELYKQYIMDNMFHDSSPTQILASELIMTSVDQISIQVSREKNLETSKARDIVINRLLQLVSTEISTPSLHISQYSNVNP", "length": 299 }, "evidence": [ { "id": "A0A1L1RS25", "url": "https://omabrowser.org/oma/group/A0A1L1RS25/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D3J9-1", "protein_name": "TLR adapter interacting with SLC15A4 on the lysosome", "gene_name": "Tasl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSEGYLSGLTYWNDIHWNCASYNEPVAGDQGKETSSVAALSYSSVDETQVQSLYVSCKSSGKFISSVHARASQHSRSQSRTVLQANSNPVFESPTLAAVGICRDVIRETYLVPPSCKSICKNYNDLHIAGGQVMAINSVMANFPSESSFEDGPLLKSSEISLSMEDSTSTQLTELPLKPIQRYSSYWRITSIKEKSSLQMQKPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASEFIMTNVDQISLQVSKEKNLDTSKVKDIVISHLLQLVSSEISTPSLHISQYSNITP", "length": 298 }, "evidence": [ { "id": "A0A1L1RS25", "url": "https://omabrowser.org/oma/group/A0A1L1RS25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAI6-1", "protein_name": "TLR adapter interacting with SLC15A4 on the lysosome", "gene_name": "TASL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP", "length": 301 }, "evidence": [ { "id": "A0A1L1RS25", "url": "https://omabrowser.org/oma/group/A0A1L1RS25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" }, { "name": "endolysosome membrane", "id": "GO:0036020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of toll-like receptor signaling pathway", "id": "GO:0034121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034121", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 7 signaling pathway", "id": "GO:0034157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034157", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" }, { "name": "regulation of lysosomal lumen pH", "id": "GO:0035751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035751", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 8 signaling pathway", "id": "GO:0034161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034161", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RS25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RS25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RS25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RS25" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RSA7-1", "uniprot_ac": "A0A1L1RSA7", "uniprot_id": "A0A1L1RSA7_CHICK", "mass": { "chemical_mass": 56596.0, "monoisotopic_mass": 56596.0 }, "refseq": { "ac": "XP_040512342", "name": "ankyrin repeat domain-containing protein 34B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512342" }, "gene_names": [ { "name": "ANKRD34B", "type": "recommended", "evidence": [ { "id": "A0A1L1RSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7" } ] }, { "name": "ANKRD34B", "type": "synonym", "evidence": [ { "id": "XP_040512342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512342" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 34B", "type": "synonym", "evidence": [ { "id": "A0A1L1RSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 34B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040512342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512342" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSA7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD34B", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7", "locus": { "chromosome": "Z", "start_pos": 64838118, "end_pos": 64801557, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007259", "url": "https://www.ensembl.org/id/ENSGALG00010007259" } ] } } ], "crossref": [ { "id": "ENSGALG00000044727", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044727", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "431626", "url": "https://www.ncbi.nlm.nih.gov/gene/431626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431626", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431626", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFPLDHN", "url": "https://omabrowser.org/oma/group/AFPLDHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RSA7", "url": "https://www.orthodb.org/?gene=A0A1L1RSA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XUC6", "url": "https://www.orthodb.org/?gene=A0A8V0XUC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040512342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RSA7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQTVELPTEGNSLIRAVYQSRLRLTRLLLEGGAYINESNNRGETPLMIACKTQHVDSQSVSKAKMVKYLLENKADPNIQDKSGKTALMHACIEKAGPEVVSLLLKSGADPSLQDHSDCSALVYAINSEDKETLKVLLNACRARGKEVIIITTDKSPSGRQTTKQYLNVSPADLEECCSTASCISPSEIELKSSPPLSGSDGTKRALFSFKDLEHPRSTDHSQPVPPRNSSSSDIGSSLAHLQQLQSEPWVKSSPSLFHQGKVSSLYEELQDITPEELSSKANGFALSKRFVTRHQNVDIKDTANVLKTADKNGSKKLYEEINYQTCYREEEHLPSGILGGKYENSSLKQISFISNLSTIIKKRNLGANHYSSDSQLTTTVHPAAAEDSKSVIGKKKTVSSSHSLFSSSRGLLEKIRSVPMSRKNETFRERRGSGALLLDNTAQTRPGFLPPLNVNLQPQIPAINFLHKVSGVISYGQKHLIPAAPASLSETKNTKTLLRRQSLQTEQIKQLVNF", "length": 515, "header": "tr|A0A1L1RSA7-1|A0A1L1RSA7_CHICK Isoform 1 of Ankyrin repeat domain 34B OS=Gallus gallus OX=9031 GN=ANKRD34B PE=3 SV=1 CANONICAL=A0A1L1RSA7-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7/entry", "sequence": { "sequence": "MNQTVELPTEGNSLIRAVYQSRLRLTRLLLEGGAYINESNNRGETPLMIACKTQHVDSQSVSKAKMVKYLLENKADPNIQDKSGKTALMHACIEKAGPEVVSLLLKSGADPSLQDHSDCSALVYAINSEDKETLKVLLNACRARGKEVIIITTDKSPSGRQTTKQYLNVSPADLEECCSTASCISPSEIELKSSPPLSGSDGTKRALFSFKDLEHPRSTDHSQPVPPRNSSSSDIGSSLAHLQQLQSEPWVKSSPSLFHQGKVSSLYEELQDITPEELSSKANGFALSKRFVTRHQNVDIKDTANVLKTADKNGSKKLYEEINYQTCYREEEHLPSGILGGKYENSSLKQISFISNLSTIIKKRNLGANHYSSDSQLTTTVHPAAAEDSKSVIGKKKTVSSSHSLFSSSRGLLEKIRSVPMSRKNETFRERRGSGALLLDNTAQTRPGFLPPLNVNLQPQIPAINFLHKVSGVISYGQKHLIPAAPASLSETKNTKTLLRRQSLQTEQIKQLVNF", "length": 515, "header": "tr|A0A1L1RSA7-1|A0A1L1RSA7_CHICK Isoform 1 of Ankyrin repeat domain 34B OS=Gallus gallus OX=9031 GN=ANKRD34B PE=3 SV=1 CANONICAL=A0A1L1RSA7-1" }, "locus": { "chromosome": "Z", "start_pos": 64810453, "end_pos": 64808909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017331.1", "url": "https://www.ensembl.org/id/ENSGALT00010017331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009599.1", "url": "https://www.ensembl.org/id/ENSGALP00010009599.1" } ] } }, { "isoform_ac": "A0A8V0XUC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUC6/entry", "sequence": { "sequence": "MNQTVELPTEGNSLIRAVYQSRLRLTRLLLEGGAYINESNNRGETPLMIACKTQHVDSQSVSKAKMVKYLLENKADPNIQDKSGKTALMHACIEKAGPEVVSLLLKSGADPSLQDHSDCSALVYAINSEDKETLKVLLNACRARGKEVIIITTDKSPSGRQTTKQYLNVSPADLEECCSTASCISPSEIELKSSPPLSGSDGTKRALFSFKDLEHPRSTDHSQPVPPRNSSSSDIGSSLAHLQQLQSEPWVKSSPSLFHQGKVSSLYEELQDITPEELSSKANGFALSKRFVTRHQNVDIKDTANVLKTADKNGSKKLYEEINYQTCYREEEHLPSGILGGKYENSSLKQISFISNLSTIIKKRNLGANHYSSDSQLTTTVHPAAAEDSKSVIGKKKTVSSSHSLFSSSRGLLEKIRSVPMSRKNETFRERRGSGALLLDNTAQTRPGFLPPLNVNLQPQIPAINFLHKVSGVISYG", "length": 477, "header": "tr|A0A8V0XUC6-1|A0A1L1RSA7_CHICK Computationally mapped isoform of Ankyrin repeat domain 34B OS=Gallus gallus OX=9031 GN=ANKRD34B PE=3 SV=1 CANONICAL=A0A1L1RSA7-1" }, "locus": { "chromosome": "Z", "start_pos": 64810339, "end_pos": 64808909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017327.1", "url": "https://www.ensembl.org/id/ENSGALT00010017327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009598.1", "url": "https://www.ensembl.org/id/ENSGALP00010009598.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BJQ9-1", "protein_name": "Ankyrin repeat domain 34Bb", "gene_name": "ankrd34bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDSVEVRTDGNSLLKAVYLCRLRLTRLLLEGGAYINESNERGETPLMVACKSHHSDAQSVPKPKIIRYLLENGADPNIQDKSGKTALMHACMERAGEEVLSLLLSSGADPSLEDHTGSSALVYAVNAGDKDALRVLLDACKAKGKEVIIITTDKLPSGRQMTKQYLNVPPPPNLEDRLHCAPASCMCPSEIKLCTPHISPPTNNRSEINLGSTQTLPISKPGSPTQVSSPLQAASVAKLLHLQRLHSEPWLKIPSSLLLQQSKSSSLTEELLDITPEEELSFGYNGCRPPMKAMVARHQSIDIKDTTGLLRAFEMTSDAERERKNEQKWLSRKMSYDGELLPHSTSHQNLKQASITDTLPVERDPDCLPNLAISSLRNVFRRRNIGMDHYSSDSQLPQFGSQPSEDLGKTGGGGTGGVEKRKLVISRSSTLSGSRESLESLVQRRSPAMLERRGSGALLLDHISQTRPGYLPPLNPHTPIPDIKANAGVGSKPVVGTAPIVAGSRHFVPCAPNHPRDYKNKKSLLRRHSMQTEQIKQLVNFEEIFGQ", "length": 548 }, "evidence": [ { "id": "A0A1L1RSA7", "url": "https://omabrowser.org/oma/group/A0A1L1RSA7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5PLL1-1", "protein_name": "Ankyrin repeat domain-containing protein 34B", "gene_name": "ANKRD34B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEGMEISSEGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQSVSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYSALVYAINSEDTETLKVLLSACKAKGKEVIIITTAKLPCGKHTTKQYLNMPPVDIDGCHSPATCTTPSEIDIKTASSPLSHSSETELTLFGFKDLELAGSNDDTWDPGSPVRKPALAPKGPKLPHAPPWVKSPPLLMHQNRVASLQEELQDITPEEELSYKTNGLALSKRFITRHQSIDVKDTAHLLRAFDQASSRKMSYDEINCQSYLSEGNQQCIEVPVDQDPDSNQTIFASTLRSIVQKRNLGANHYSSDSQLSAGLTPPTSEDGKALIGKKKILSPSPSQLSESKELLENIPPGPLSRRNHAVLERRGSGAFPLDHSVTQTRQGFLPPLNVNSHPPISDINVNNKICSLLSCGQKVLMPTVPIFPKEFKSKKMLLRRQSLQTEQIKQLVNF", "length": 514 }, "evidence": [ { "id": "A0A1L1RSA7", "url": "https://omabrowser.org/oma/group/A0A1L1RSA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZKP1-1", "protein_name": "Ankyrin repeat domain 34B", "gene_name": "Ankrd34b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEGSEVSTDGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDQQSVGRAKMVKYLLENSADPNIQDKSGKSALMHACLERAGPEVVSLLLKSGADLSLQDHSGYSALVYAINAEDRDTLKVLLSACQAKGKEVIIITTAKSPSGRHTTQQYLNMPPADMDGSHPPATPSEIDIKTASLPLSYSSETDLTLFGFKDRELSGSSDNTWDPDSPRRRPGMATNGPKLSQAPAWIKSTPSLKHQARVASLQEELQDISPEEEVAYKTNALALSKRFITRHQSIDVKDTVHLLRAFDQVNSRKMSYDEINYHSLFPEGNQSCVETPTDQDPDSSQIFASTLKNIVQKRNSGANHYSSDSQLAEGITPPTSEDGKASKKKIFAPSPSLLSGSKELVETAPPGPLSRRNHAVLERRGSGAFPIDHSLAQSRPGFLPPLNVNPHPPITDIGVNNKICGLLSCGQKVLMPTAPIFPKEFKTKKMLLRRQSLQTEQIKQLVNF", "length": 508 }, "evidence": [ { "id": "A0A1L1RSA7", "url": "https://omabrowser.org/oma/group/A0A1L1RSA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RF21-1", "protein_name": "Ankyrin repeat domain 34B", "gene_name": "ANKRD34B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDEGIEISSDGKSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQSVSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYSALVYAINSEDRETLKVLLSACKAKGKEVIIITTAKSPSGRHTTKQYLNMPPVDMDGCHPPATCATPSEIDLKTASSPPSHSSETEMTLFGFKDLEAPGSSDDTRDPDSPVRKPGMAPNGPKLPQASHWIKSPPLLMHQNRVASLQEELQDITPEEELSYKTNGLALSKRFITRHQSIDVKDTAHLLRAFDQASSRKMSYDEINYQSFFSEGNQQCIEIPVDQDSDSNQTIFASTLRNIVQKRNSGANHYSSDSQLSAGLTPTTLEDGKALIGKKKILSPSPSLLSGSKELLENIPPGPLSRRNHALLERRGSGAFSLDHNITQTRPGFLPPLNVNPHPPISDINVNKISNLLSCGQKVLMPTVPMYPKEFRSKKMLLRRQSLQTEQIKQLVNF", "length": 513 }, "evidence": [ { "id": "A0A1L1RSA7", "url": "https://omabrowser.org/oma/group/A0A1L1RSA7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UUF8-1", "protein_name": "Ankyrin repeat domain-containing protein 34B", "gene_name": "Ankrd34b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEGSEVSTDGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDQQSVGRAKMVKYLLENSADPNIQDKSGKSALMHACLERAGPEVVSLLLKSGADLSLQDHSGYSALVYAINAEDRDTLKVLLSACQAKGKEVIIITTAKSPSGRHTTQHHLNMPPADMDGSHPPATPSEIDIKTASLPLSYSSETDLTLFGFKDKELCGGSDNTWDPDSPPRKPVIATNGPKLSQAPAWIKSTPSLKHQARVASLQEELQDITPEEEIAYKTNALALSKRFITRHQSIDVKDTAHLLRAFDQVNSRKMSYDEINYHSLFPEGSQTSVEIPTDRDPDSNQIFASTLKSIVQKRNSGANHYSSDSQLAEGVTPPTVEDGKAAKKKIFAPSPSLLSGSKELVEPAPPGPLSRRNHAVLERRGSGAFPLDHSLAQSRPGFLPPLNVNPHPPITDIGVNNKICGLLSCGQKALMPTAPIFPKEFKTKKMLLRRQSLQTEQIKQLVNF", "length": 508 }, "evidence": [ { "id": "A0A1L1RSA7", "url": "https://omabrowser.org/oma/group/A0A1L1RSA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSA7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RSL3-1", "uniprot_ac": "A0A1L1RSL3", "uniprot_id": "A0A1L1RSL3_CHICK", "mass": { "chemical_mass": 39537.0, "monoisotopic_mass": 39537.0 }, "refseq": { "ac": "XP_004934660", "name": "probable G-protein coupled receptor 82", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934660" }, "gene_names": [ { "name": "GPR82", "type": "recommended", "evidence": [ { "id": "A0A1L1RSL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3" } ] }, { "name": "GPR82", "type": "synonym", "evidence": [ { "id": "XP_004934660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934660" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 82", "type": "synonym", "evidence": [ { "id": "A0A1L1RSL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 82", "type": "synonym", "evidence": [ { "id": "XP_004934660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934660" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934660" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSL3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR82", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3", "locus": { "chromosome": "1", "start_pos": 111979696, "end_pos": 111982521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002439", "url": "https://www.ensembl.org/id/ENSGALG00010002439" } ] } } ], "crossref": [ { "id": "A0A1L1RSL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RSL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000044763", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044763", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101750076", "url": "https://www.ncbi.nlm.nih.gov/gene/101750076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750076", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKNTCIG", "url": "https://omabrowser.org/oma/group/QKNTCIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RSL3", "url": "https://www.orthodb.org/?gene=A0A1L1RSL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47392", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47392", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47392:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47392:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RSL3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RSL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNSTCVLHPSIATTVALPVIYSLLFITGSFGNILTAWVFSRQASTKRTQYIYLVNLVTANLLVCSTMPFLAGYFAKGHEWTYSSDVCRAAYHLGTTVMHVCMYVTITILCTIALSQYATLKKNNNARHSPAVTKSLYKRGLQKFRQPKFAKYFCIFIWLIVLCATITAIAFDAQARREQIFHTCYNTKVEIGEFTAKTAASFATACFFLFFLTVLLSYYSLTRHLSKIQKNTHFGQNHMIYRTVKRNILVIQIILTVCFLPYHIFKPIFYVLLPEEDCSRINYLVEIKNFLTCLCVSRSSIDPVMTLLIDKTFKKSLYSLFKKSIPDHHQRRADIFTEEIPPM", "length": 344, "header": "tr|A0A1L1RSL3-1|A0A1L1RSL3_CHICK Isoform 1 of G protein-coupled receptor 82 OS=Gallus gallus OX=9031 GN=GPR82 PE=4 SV=1 CANONICAL=A0A1L1RSL3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RSL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3/entry", "sequence": { "sequence": "MRNSTCVLHPSIATTVALPVIYSLLFITGSFGNILTAWVFSRQASTKRTQYIYLVNLVTANLLVCSTMPFLAGYFAKGHEWTYSSDVCRAAYHLGTTVMHVCMYVTITILCTIALSQYATLKKNNNARHSPAVTKSLYKRGLQKFRQPKFAKYFCIFIWLIVLCATITAIAFDAQARREQIFHTCYNTKVEIGEFTAKTAASFATACFFLFFLTVLLSYYSLTRHLSKIQKNTHFGQNHMIYRTVKRNILVIQIILTVCFLPYHIFKPIFYVLLPEEDCSRINYLVEIKNFLTCLCVSRSSIDPVMTLLIDKTFKKSLYSLFKKSIPDHHQRRADIFTEEIPPM", "length": 344, "header": "tr|A0A1L1RSL3-1|A0A1L1RSL3_CHICK Isoform 1 of G protein-coupled receptor 82 OS=Gallus gallus OX=9031 GN=GPR82 PE=4 SV=1 CANONICAL=A0A1L1RSL3-1" }, "locus": { "chromosome": "1", "start_pos": 111980946, "end_pos": 111979915, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005614.1", "url": "https://www.ensembl.org/id/ENSGALT00010005614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003453.1", "url": "https://www.ensembl.org/id/ENSGALP00010003453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101750076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750076", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LTU5-1", "protein_name": "Probable G-protein coupled receptor 82", "gene_name": "Gpr82", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNNNSTCIQPSMISTTALPIIYIFLCIIGLFGNSLAQWVFLTKIGKKTSTHVYLANLVTANLLVCTAMPFMGIYFLKGFYWKYQSLQCRLVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKESMQEATSCYERMFYGHLLKRFRQPNFARKMCIYIWGVVLVIIIPVILYYSVVEATEEGESQCYNRRMELGASISQIAGLIGTTFIGFSFLVVVTSYYSFVSHLRRVRTCTSITERDLTYRSVRKHLLIIQVLLVVCFLPYSIFKPIFYVLHQREDCQQLNYLIEAKNILTCLASARSSTDPIIFLLLDKTFKKTLHNLLTKS", "length": 327 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A217-1", "protein_name": "G protein-coupled receptor 82", "gene_name": "Gpr82", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNNSTCIQPSVISTTALPITYIFLCIVGLFGNSLAQWVFLTKIGKKTSTHIYLANLVTANLLVCTAMPFMGAYFLRGFYWKYQSVQCRLVNFLGTLSLHVSMFVSLIILSWIAISRYATLMKKESMQEATSCYERIFYGHLLKRFRQPKFARATCIYIWGVVLVVIIPVILYYSVVEATEDGESHCYNRRMELGASPSQIAGLIGTTFIGFSFLVVVTSYYSFVSHLRRVRTCTSITERDLTYRSVKRHLLIIQVLLVVCFLPYSIFKPIFYVLHQKEEDCQQLNYLIEAKNILTCLASARSSTDPIIFLLLDKTFKKTLYDLITKS", "length": 328 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RX04-1", "protein_name": "G protein-coupled receptor 82", "gene_name": "GPR82", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNNSTCIQPSMISSMALPITYIFLCIIGLFGNSLSQWIFLTKIAKKTSTHIYLAHLVTANLLVCSAMPFMGIYFLKGFQWEYQSAQCRVVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKDSTQETTSCYEKIFYGHLLKKFRQPNFARKLCVYIWVVVLGIIIPVILYYSVVEATEGEEKVCYNRQMELGAMLSQIAGLIGTTFIGFSFLVVLTSYYSFVSHLRKIRTCTSITEKDLTYSSVKRHLLVIQILLVVCFLPYSIFKPIFFVLHQGKDCQQLNYLIEIKNILTCLASARSSTDPIIFLFLDKTFKKIVYNLFTKPDSPHIQTSG", "length": 336 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G5E6S1-1", "protein_name": "G protein-coupled receptor 82", "gene_name": "GPR82", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNNSTCIQPSKISYMALPIIYTFLCIIGLFGNSLSQWIFLTKIAKKTSTHIYLAHLVTANLLVCSAMPFMGIYFLKGFQWEYQSPQCRVVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKDSTQETTSCYEKVFYGHLLKKFRQPNFARKLCVYIWIVVLGIIIPIIIYYSVEETTKGEETKCYNSQMELGAEISQTAGLIGTTFIGFSFLVVLTSYYSFVNHLRKIRTCTSITEKDLTYSSVKRHLLVIQILLIVCFLPYSIFKPIFFVVHRRLDCQQLNDLIEIKNILTCLASARSSTDPIIFLFLDKTFKKTLYNLFTKPDAPHLQPSD", "length": 336 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BZR0-1", "protein_name": "Probable G protein-coupled receptor 82", "gene_name": "Gpr82", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNNSTCIQPSVISTTALPVTYIFLFIIGLFGNSLAQWVFLTKIGKKTSTHIYLANLVTANLLVCTAMPFMGIYFLRGFYWKYQSVQCRLVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKESKQEATSCYERMFYGHVLKRFRQPNFARTMCIYIWGVVLVIIIPVTLYYSVVEATEEGQSQCYNRQMELGARPSQIAGLIGTTFIGFSFLVVVTSYYSLVSHLRRVRTCTSITEKDLTYRSVKRHLLIIQVLLVVCFLPYSIFKPIFYVLHQREGDCQQLNYLIEAKNILTCLASARSSTDPIIFLLLDKTFKKTLYGLLTKS", "length": 328 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P67-1", "protein_name": "Probable G protein-coupled receptor 82", "gene_name": "GPR82", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNNTTCIQPSMISSMALPIIYILLCIVGVFGNTLSQWIFLTKIGKKTSTHIYLSHLVTANLLVCSAMPFMSIYFLKGFQWEYQSAQCRVVNFLGTLSMHASMFVSLLILSWIAISRYATLMQKDSSQETTSCYEKIFYGHLLKKFRQPNFARKLCIYIWGVVLGIIIPVTVYYSVIEATEGEESLCYNRQMELGAMISQIAGLIGTTFIGFSFLVVLTSYYSFVSHLRKIRTCTSIMEKDLTYSSVKRHLLVIQILLIVCFLPYSIFKPIFYVLHQRDNCQQLNYLIETKNILTCLASARSSTDPIIFLLLDKTFKKTLYNLFTKSNSAHMQSYG", "length": 336 }, "evidence": [ { "id": "A0A1L1RSL3", "url": "https://omabrowser.org/oma/group/A0A1L1RSL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSL3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSL3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RSL3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RSL3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RSL3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RSL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSL3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 307, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RSX7-1", "uniprot_ac": "A0A1L1RSX7", "uniprot_id": "A0A1L1RSX7_CHICK", "mass": { "chemical_mass": 18264.0, "monoisotopic_mass": 18264.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107055485", "type": "recommended", "evidence": [ { "id": "A0A1L1RSX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL22", "type": "recommended", "evidence": [ { "id": "A0A1L1RSX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L17", "type": "synonym", "evidence": [ { "id": "A0A1L1RSX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSX7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055485", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7", "locus": {} } ], "crossref": [ { "id": "A0A1L1RSX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RSX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041500", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041500", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RSX7", "url": "https://www.orthodb.org/?gene=A0A1L1RSX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11593:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11593:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RSX7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RSX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "NTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 157, "header": "tr|A0A1L1RSX7-1|A0A1L1RSX7_CHICK Isoform 1 of Large ribosomal subunit protein uL22 OS=Gallus gallus OX=9031 GN=LOC107055485 PE=3 SV=1 CANONICAL=A0A1L1RSX7-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RSX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7/entry", "sequence": { "sequence": "NTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 157, "header": "tr|A0A1L1RSX7-1|A0A1L1RSX7_CHICK Isoform 1 of Large ribosomal subunit protein uL22 OS=Gallus gallus OX=9031 GN=LOC107055485 PE=3 SV=1 CANONICAL=A0A1L1RSX7-1" }, "locus": { "chromosome": "W", "start_pos": 4063776, "end_pos": 4062040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029404.1", "url": "https://www.ensembl.org/id/ENSGALT00010029404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017079.1", "url": "https://www.ensembl.org/id/ENSGALP00010017079.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSX7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSX7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RSX7", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RSX7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 157, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RSX7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RSX7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A1L1RT00-1", "uniprot_ac": "A0A1L1RT00", "uniprot_id": "A0A1L1RT00_CHICK", "mass": { "chemical_mass": 35736.0, "monoisotopic_mass": 35736.0 }, "refseq": { "ac": "NP_990044", "name": "retinol dehydrogenase 5 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" }, "gene_names": [ { "name": "RDH5", "type": "recommended", "evidence": [ { "id": "A0A1L1RT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ] }, { "name": "RDH5", "type": "synonym", "evidence": [ { "id": "NP_990044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" } ] } ], "protein_names": [ { "name": "11-cis retinol dehydrogenase", "type": "synonym", "evidence": [ { "id": "NP_990044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" } ] }, { "name": "Retinol dehydrogenase 5", "type": "synonym", "evidence": [ { "id": "A0A1L1RT00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00/entry#names_and_taxonomy" } ] }, { "name": "retinol dehydrogenase 5 (11-cis/9-cis)", "type": "synonym", "evidence": [ { "id": "NP_990044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" } ] }, { "name": "retinol dehydrogenase 5 precursor", "type": "synonym", "evidence": [ { "id": "NP_990044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF285079.1, SRR13267659.311606.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738229 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000491.1. On Oct 29, 2021 this sequence version replaced NP_990044.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RDH5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00", "locus": { "chromosome": "34", "start_pos": 1813371, "end_pos": 1817309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022931", "url": "https://www.ensembl.org/id/ENSGALG00010022931" } ] } } ], "crossref": [ { "id": "A0A1L1RT00", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RT00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034988", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09805", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09805", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395452", "url": "https://www.ncbi.nlm.nih.gov/gene/395452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395452", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEDFHQV", "url": "https://omabrowser.org/oma/group/WEDFHQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RT00", "url": "https://www.orthodb.org/?gene=A0A1L1RT00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK90", "url": "https://www.orthodb.org/?gene=A0A8V0ZK90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43313", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43313", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43313:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43313:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLYLLLVVLAWALGWLVRDRQTLPSVKDKHVFITGCDSGFGNLLARRLAQRGFRVLAACLTPQGADGLQRGCAGHLRTTLLDVTRSDSIRRAAEWVREEVGEKGLFGLVNNAGVANPIGPTEWMRIEDYRQVMAVNTFGAIEVTLQLLPLLKRARGRVVNTSSVLGRLSANGGGYCVSKYCIEAFSDSLRRDMYHFGVKVSIVEPGFFKTAVTNLESIEASLRQLWERLAPETRLSYGEEFFHKYLKVQRFIMNIICDADLGKVTRCMEHALGACHPRTRYSAGWDAKLLWLPASYLPACIVDFVLATILPKPAHHVR", "length": 319, "header": "tr|A0A1L1RT00-1|A0A1L1RT00_CHICK Isoform 1 of Retinol dehydrogenase 5 OS=Gallus gallus OX=9031 GN=RDH5 PE=3 SV=2 CANONICAL=A0A1L1RT00-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00/entry", "sequence": { "sequence": "MWLYLLLVVLAWALGWLVRDRQTLPSVKDKHVFITGCDSGFGNLLARRLAQRGFRVLAACLTPQGADGLQRGCAGHLRTTLLDVTRSDSIRRAAEWVREEVGEKGLFGLVNNAGVANPIGPTEWMRIEDYRQVMAVNTFGAIEVTLQLLPLLKRARGRVVNTSSVLGRLSANGGGYCVSKYCIEAFSDSLRRDMYHFGVKVSIVEPGFFKTAVTNLESIEASLRQLWERLAPETRLSYGEEFFHKYLKVQRFIMNIICDADLGKVTRCMEHALGACHPRTRYSAGWDAKLLWLPASYLPACIVDFVLATILPKPAHHVR", "length": 319, "header": "tr|A0A1L1RT00-1|A0A1L1RT00_CHICK Isoform 1 of Retinol dehydrogenase 5 OS=Gallus gallus OX=9031 GN=RDH5 PE=3 SV=2 CANONICAL=A0A1L1RT00-1" }, "locus": { "chromosome": "34", "start_pos": 1816339, "end_pos": 1814157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055799.1", "url": "https://www.ensembl.org/id/ENSGALT00010055799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033779.1", "url": "https://www.ensembl.org/id/ENSGALP00010033779.1" } ] } }, { "isoform_ac": "A0A8V0ZK90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK90/entry", "sequence": { "sequence": "MWLYLLLVVLAWALGWLVRDRQTLPSVKDKHVFITGCDSGFGNLLARRLAQRGFRVLAACLTPQGADGLQRGCAGHLRTTLLDVTRSDSIRRAAEWVREEVGEKGLFGLVNNAGVANPIGPTEWMRIEDYRQVMAVNTFGAIEVTLQLLPLLKRARGRVVNTSSVLGRLSANGGGYCVSKYCIEAFSDSLRRDMYHFGVKVSIVEPGFFKTAVTNLESIEASLRQLWERLAPETRLSYGEEFFHKCEWWEGAAGPPPSWAPVGWPLPPWGPLGWPPPLPGPHWQHSSWTPVGLATPFFQGPRWVGHPLLLGAHWVGHPSSWAPLALATLFQGPPLGWPPPSSRALLGLATPSFLGPPLGWPPPPSWGPLALATLFLDPSWVGHSLLPWPPLGWPPPSSWTPTALATSFFLGPLGWPPLSSWGPLGWPPPSSWAPTGLATPFFLGPHWVGHTHGPTPQSSDPHQPNQT", "length": 467, "header": "tr|A0A8V0ZK90-1|A0A8V0ZK90_CHICK Computationally mapped isoform of Retinol dehydrogenase 5 OS=Gallus gallus OX=9031 GN=RDH5 PE=3 SV=1 CANONICAL=A0A1L1RT00-1" }, "locus": { "chromosome": "34", "start_pos": 1816339, "end_pos": 1814375, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055803.1", "url": "https://www.ensembl.org/id/ENSGALT00010055803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033783.1", "url": "https://www.ensembl.org/id/ENSGALP00010033783.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395452", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395452", "resource": "KEGG Pathway" }, { "id": "R-GGA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-GGA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZKU7-1", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "gene_name": "Bloc1s1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS", "length": 125 }, "evidence": [ { "id": "A0A1L1RT00", "url": "https://omabrowser.org/oma/group/A0A1L1RT00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55240-1", "protein_name": "Retinol dehydrogenase 5", "gene_name": "Rdh5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLPLLLGALLWAVLWLLRDRQSLPASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSGAEDLQQMASSRLHTTLLDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARGRVVNITSVLGRIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMNLICDPELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARVVDAVLTWILPRPAQSVS", "length": 318 }, "evidence": [ { "id": "A0A1L1RT00", "url": "https://omabrowser.org/oma/group/A0A1L1RT00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q27979-1", "protein_name": "Retinol dehydrogenase 5", "gene_name": "RDH5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLPLLLGVLLWAALWLLRDRQCLPASDAFIFITGCDSGFGRLLALRLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDVTDPQSIRQAVKWVETHVGEAGLFGLVNNAGVAGIIGPTPWQTREDFQRVLNVNTLGPIGVTLALLPLLLQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAPFGVRVSIVEPGFFRTPVTNLETLEDTLQACWARLPPATQALYGEAFLTKYLRVQQRIMNMICDPDLAKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARLVDAVLAWVLPKPAQTVY", "length": 318 }, "evidence": [ { "id": "A0A1L1RT00", "url": "https://omabrowser.org/oma/group/A0A1L1RT00/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q92781-1", "protein_name": "Retinol dehydrogenase 5", "gene_name": "RDH5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY", "length": 318 }, "evidence": [ { "id": "A0A1L1RT00", "url": "https://omabrowser.org/oma/group/A0A1L1RT00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "retinoid metabolic process", "id": "GO:0001523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001523", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ], "pmid": "" }, { "name": "steroid metabolic process", "id": "GO:0008202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT00", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 122 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RT72-1", "uniprot_ac": "A0A1L1RT72", "uniprot_id": "A0A1L1RT72_CHICK", "mass": { "chemical_mass": 26717.0, "monoisotopic_mass": 26717.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "UDP-N-acetylglucosamine transferase subunit ALG13", "type": "recommended", "evidence": [ { "id": "A0A1L1RT72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.141", "type": "synonym", "evidence": [ { "id": "A0A1L1RT72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT72", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72", "locus": {} } ], "crossref": [ { "id": "A0A1L1RT72", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RT72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030718", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12867", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12867", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12867:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12867:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446193", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446193", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RT72", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RT72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTVFVTVGTTSFDELIAAVSSPAAEQVRRRNARFGGRQEEGPSPPLAAGLPCLSSAPARWLRGRLWGAARSCTEGGKREPFCGEWEAVEGEPAVLSSGLSPASVPPPQVLRSRGCRQLVLQIGRGALQPAPQYGPAFVRDVFRFKESLAEDLRRADLVISHAGAGSCLETLEEGKPLLVVINEKLMDNHQLELARQLHKDGHVLYCNCSTLVETLQSMDLSTLKPFPPGQPEKFALFLDKVVGFE", "length": 246, "header": "tr|A0A1L1RT72-1|A0A1L1RT72_CHICK Isoform 1 of UDP-N-acetylglucosamine transferase subunit ALG13 OS=Gallus gallus OX=9031 GN= PE=1 SV=2 CANONICAL=A0A1L1RT72-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RT72-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72/entry", "sequence": { "sequence": "MKTVFVTVGTTSFDELIAAVSSPAAEQVRRRNARFGGRQEEGPSPPLAAGLPCLSSAPARWLRGRLWGAARSCTEGGKREPFCGEWEAVEGEPAVLSSGLSPASVPPPQVLRSRGCRQLVLQIGRGALQPAPQYGPAFVRDVFRFKESLAEDLRRADLVISHAGAGSCLETLEEGKPLLVVINEKLMDNHQLELARQLHKDGHVLYCNCSTLVETLQSMDLSTLKPFPPGQPEKFALFLDKVVGFE", "length": 246, "header": "tr|A0A1L1RT72-1|A0A1L1RT72_CHICK Isoform 1 of UDP-N-acetylglucosamine transferase subunit ALG13 OS=Gallus gallus OX=9031 GN= PE=1 SV=2 CANONICAL=A0A1L1RT72-1" }, "locus": { "chromosome": "4", "start_pos": 13140106, "end_pos": 13137012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036902.1", "url": "https://www.ensembl.org/id/ENSGALT00010036902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021489.1", "url": "https://www.ensembl.org/id/ENSGALP00010021489.1" } ] } }, { "isoform_ac": "A0A8V0YS04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS04/entry", "sequence": { "sequence": "MKTVFVTVGTTSFDELIAAVSSPAAEQVLRSRGCRQLVLQIGRGALQPAPQYGPAFVRDVFRFKESLAEDLRRADLVISHAGAGSCLETLEEGKPLLVVINEKLMDNHQLELARQLHKDGHVLYCNCRYGAAVAVTLDAVLRSITVITVLRM", "length": 152, "header": "tr|A0A8V0YS04-1|A0A1L1RT72_CHICK Computationally mapped isoform of UDP-N-acetylglucosamine transferase subunit ALG13 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1L1RT72-1" }, "locus": { "chromosome": "4", "start_pos": 13140106, "end_pos": 13139196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036904.1", "url": "https://www.ensembl.org/id/ENSGALT00010036904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021490.1", "url": "https://www.ensembl.org/id/ENSGALP00010021490.1" } ] } }, { "isoform_ac": "A0A8V0YTQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTQ5/entry", "sequence": { "sequence": "RWLRGRLWGAARSCTEGGKREPFCGEWEAVEGEPAVLSSGLSPASVPPPQIGRGALQPAPQYGPAFVRDVFRFKESLAEDLRRADLVISHAGAGSCLETLEEGKPLLVVINEKLMDNHQLELARQLHKDGHVLYCNCSTLVETLQSMDLSTLKPFPPGQPEKFALFLDKVVGFE", "length": 174, "header": "tr|A0A8V0YTQ5-1|A0A1L1RT72_CHICK Computationally mapped isoform of UDP-N-acetylglucosamine transferase subunit ALG13 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A1L1RT72-1" }, "locus": { "chromosome": "4", "start_pos": 13139929, "end_pos": 13137012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036898.1", "url": "https://www.ensembl.org/id/ENSGALT00010036898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021486.1", "url": "https://www.ensembl.org/id/ENSGALP00010021486.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-446193", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446193", "resource": "Reactome", "description": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT72", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT72", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity", "id": "GO:0004577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004577", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RT72", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RT72-1" ], "evidence": [ { "id": "R-GGA-446207", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446207" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1L1RT72", "gene_name": "", "activity": [ { "ec_number": "2.4.1.141", "activity": "an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+).", "evidence": [ { "id": "A0A1L1RT72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ] }, { "ec_number": "2.4.1.141", "activity": "", "evidence": [ { "id": "A0A1L1RT72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RT72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RT72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RT72" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RT72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RT72" }, { "id": "PF04101", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04101" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase family 28 C-terminal", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 228, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.141", "ec_name": "an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+).", "evidence": [ { "id": "2.4.1.141", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.141" }, { "id": "2.4.1.141", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.141" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 7 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642901" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUD0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859850", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD0", "locus": {} } ], "crossref": [ { "id": "A0A1L1RUD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RUD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859850", "url": "https://www.ncbi.nlm.nih.gov/gene/100859850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:100859850", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFCRISQ", "url": "https://omabrowser.org/oma/group/VFCRISQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RUD0", "url": "https://www.orthodb.org/?gene=A0A1L1RUD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_003642901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642901", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RUD0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RUD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQSAKPCTNPEWAELLQGLMVTSSEPGSFSSRFLHQVLQLGLVRSLLKMLQKVSVWVGFVVPVEAIISRVCPVQSPHRPTRFAKKRHGRLKRFLLAFIPTRIQAVLGRLPTDWGQNNMPKEVREALINPSSKANKRKRDDVALEEQESWVVVLEKDLPEDDPEDLSYEPSEVDTDTEEYKSQNNTETDLEFEEHEGAIMLKESLDLQLDDAQPSGDEDNPELLAVSSEQGQEDPAASGSAEDASNDDSGDSDTQTPRDVSSRDSSEQEADVERESSSSS", "length": 280, "header": "tr|A0A1L1RUD0-1|A0A1L1RUD0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC100859850 PE=1 SV=2 CANONICAL=A0A1L1RUD0-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RUD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD0/entry", "sequence": { "sequence": "MEQSAKPCTNPEWAELLQGLMVTSSEPGSFSSRFLHQVLQLGLVRSLLKMLQKVSVWVGFVVPVEAIISRVCPVQSPHRPTRFAKKRHGRLKRFLLAFIPTRIQAVLGRLPTDWGQNNMPKEVREALINPSSKANKRKRDDVALEEQESWVVVLEKDLPEDDPEDLSYEPSEVDTDTEEYKSQNNTETDLEFEEHEGAIMLKESLDLQLDDAQPSGDEDNPELLAVSSEQGQEDPAASGSAEDASNDDSGDSDTQTPRDVSSRDSSEQEADVERESSSSS", "length": 280, "header": "tr|A0A1L1RUD0-1|A0A1L1RUD0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC100859850 PE=1 SV=2 CANONICAL=A0A1L1RUD0-1" }, "locus": { "chromosome": "28", "start_pos": 2384290, "end_pos": 2382310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069039.1", "url": "https://www.ensembl.org/id/ENSGALT00010069039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042481.1", "url": "https://www.ensembl.org/id/ENSGALP00010042481.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859850", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RUD0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 280, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RUD0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RUD0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RUD3-1", "uniprot_ac": "A0A1L1RUD3", "uniprot_id": "A0A1L1RUD3_CHICK", "mass": { "chemical_mass": 23262.0, "monoisotopic_mass": 23262.0 }, "refseq": { "ac": "XP_421270", "name": "rRNA-processing protein FCF1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421270" }, "gene_names": [ { "name": "FCF1", "type": "recommended", "evidence": [ { "id": "A0A1L1RUD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3" } ] }, { "name": "FCF1", "type": "synonym", "evidence": [ { "id": "XP_421270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421270" } ] } ], "protein_names": [ { "name": "rRNA-processing protein FCF1 homolog", "type": "recommended", "evidence": [ { "id": "A0A1L1RUD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3/entry#names_and_taxonomy" } ] }, { "name": "rRNA-processing protein FCF1 homolog", "type": "synonym", "evidence": [ { "id": "XP_421270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421270" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421270" } ] }, { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUD3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3#function" }, { "database": "UniProtKB", "id": "ARBA00035000", "url": "https://www.uniprot.org/uniprotkb/ARBA00035000#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RUD3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FCF1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3", "locus": { "chromosome": "5", "start_pos": 37541684, "end_pos": 37536117, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005989", "url": "https://www.ensembl.org/id/ENSGALG00010005989" } ] } } ], "crossref": [ { "id": "A0A1L1RUD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RUD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010275", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423355", "url": "https://www.ncbi.nlm.nih.gov/gene/423355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423355", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMMDCLL", "url": "https://omabrowser.org/oma/group/GMMDCLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RUD3", "url": "https://www.orthodb.org/?gene=A0A1L1RUD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RUD3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RUD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKQKKARKYAVMKRMISLRDHRINEKDRAKAPAKKKEDPSAIKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQRYRVALRIAKDPRFERLPCMHKGTYADDCLVQRVTQHKCYIVATVDKELKRRIRKIPGVPIMYISRHRYNIERMPDDYGAPRF", "length": 198, "header": "tr|A0A1L1RUD3-1|A0A1L1RUD3_CHICK Isoform 1 of rRNA-processing protein FCF1 homolog OS=Gallus gallus OX=9031 GN=FCF1 PE=3 SV=2 CANONICAL=A0A1L1RUD3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RUD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUD3/entry", "sequence": { "sequence": "MGKQKKARKYAVMKRMISLRDHRINEKDRAKAPAKKKEDPSAIKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQRYRVALRIAKDPRFERLPCMHKGTYADDCLVQRVTQHKCYIVATVDKELKRRIRKIPGVPIMYISRHRYNIERMPDDYGAPRF", "length": 198, "header": "tr|A0A1L1RUD3-1|A0A1L1RUD3_CHICK Isoform 1 of rRNA-processing protein FCF1 homolog OS=Gallus gallus OX=9031 GN=FCF1 PE=3 SV=2 CANONICAL=A0A1L1RUD3-1" }, "locus": { "chromosome": "5", "start_pos": 37540023, "end_pos": 37536154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014321.1", "url": "https://www.ensembl.org/id/ENSGALT00010014321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008407.1", "url": "https://www.ensembl.org/id/ENSGALP00010008407.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423355", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TD48-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "FCF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKQKKTRKYAIMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MDU6-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Fcf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O82346-1", "protein_name": "PIN domain-like family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKAKKPQKFAVVKKMISHKALKHYKEEVLNPNKKDLTELPRNVPSVPAGLFFSYNSTLVPPYRVLVDTNFINFSIQNKIDLEKGMRDCLYANCTPCITDCVMAELEKLGQKYRVALRIAKDPHFERLPCIHKGTYADDCLVDRVTQHKCFIVATCDRDLKRRIRKIPGVPIMYVTNRKYSIEKLPEATLGGAPRY", "length": 196 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q05498-1", "protein_name": "rRNA-processing protein FCF1", "gene_name": "FCF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKAKKTRKFGLVKRTLNTKKDQRLKKNQENIKTKEDPELTRNIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF", "length": 189 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1RP75-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "Fcf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "GKQKKTRKYATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "length": 197 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32PD0-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "FCF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "length": 198 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55GM5-1", "protein_name": "rRNA-processing protein FCF1 homolog", "gene_name": "fcf1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARKPGLAPKKVPLQKLNKTNPNFSNRQKQIQRSKQEDEHRKKLEEIPEDNTSHMFFSYNEALVPPYHVIIDTNFINFSISHKLDIIHSLMDCLYAKCIPYISDCVAAEIERLGSKFKVALKISKDPRFQRLTCSHKGTYADDCIINRITMHRMFIVATCDADLRRRIRKIPGVPIVYLKGKKYTVERMPDLLQ", "length": 194 }, "evidence": [ { "id": "A0A1L1RUD3", "url": "https://omabrowser.org/oma/group/A0A1L1RUD3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { 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"uniprot_ac": "A0A1L1RUU9", "uniprot_id": "A0A1L1RUU9_CHICK", "mass": { "chemical_mass": 19883.0, "monoisotopic_mass": 19883.0 }, "refseq": { "ac": "XP_001233329", "name": "myosin regulatory light chain 2, smooth muscle minor isoform", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233329" }, "gene_names": [ { "name": "MYL12B", "type": "recommended", "evidence": [ { "id": "A0A1L1RUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUU9" } ] }, { "name": "MYL12B", "type": "synonym", "evidence": [ { "id": "XP_001233329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233329" } ] } ], "protein_names": [ { "name": "Myosin light chain 12B", "type": "synonym", "evidence": [ { "id": "A0A1L1RUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUU9/entry#names_and_taxonomy" } ] }, { "name": "myosin regulatory light chain 2, smooth muscle minor isoform", "type": "synonym", "evidence": [ { "id": "XP_001233329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233329" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233329.1. 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"tr|A0A1L1RUU9-1|A0A1L1RUU9_CHICK Isoform 1 of Myosin light chain 12B OS=Gallus gallus OX=9031 GN=MYL12B PE=4 SV=2 CANONICAL=A0A1L1RUU9-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RUU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUU9/entry", "sequence": { "sequence": "MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGFIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD", "length": 172, "header": "tr|A0A1L1RUU9-1|A0A1L1RUU9_CHICK Isoform 1 of Myosin light chain 12B OS=Gallus gallus OX=9031 GN=MYL12B PE=4 SV=2 CANONICAL=A0A1L1RUU9-1" }, "locus": { "chromosome": "2", "start_pos": 100494423, "end_pos": 100490205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005328.1", "url": "https://www.ensembl.org/id/ENSGALT00010005328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003167.1", "url": "https://www.ensembl.org/id/ENSGALP00010003167.1" } ] } }, { "isoform_ac": 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gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052596.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"Protein Classification" ] }, { "id": "PTHR12394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12394:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040546535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040546535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A527", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A527", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A527-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A527-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPLVSLEEEFEEGPGDNGGVPRRTMDPALAELESFSTEMMSFKSMEDLVQEFDEKLTVCFRNYDATTEGLAPVRGRLQAQEEEEHLQDEEVWDALTDGFVPRGSPRPWMHPEAEAPDGTDPQLCEKEDEELAERSEHDSGINEEPLLTAEQVIEELEELMQSSPDPEADPEGDEDEEEEEDEEEDAEANAEGDSGSRGMEPIVLHELHTFSPTFNNNCSHEGLEQLTAGELAAAAGRAEAASRALSAELVAQLARRDELAFEKEVKTAFIGALLAVQGEQREQREAARRRRRDRGLSLQGGRPERGGHMPRKRFSMEGISSILHSGLRQTFGPAANEKQYLNTVIPYEKKGSPPSVEDLQMLTNILFAMKEGNEKVPTLLTDYILKVLCPT", "length": 393, "header": "tr|A0A1L1RVA3-1|A0A1L1RVA3_CHICK Isoform 1 of Fasciculation and elongation protein zeta 1 OS=Gallus gallus OX=9031 GN=FEZ1 PE=3 SV=2 CANONICAL=A0A1L1RVA3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3/entry", "sequence": { "sequence": "MEAPLVSLEEEFEEGPGDNGGVPRRTMDPALAELESFSTEMMSFKSMEDLVQEFDEKLTVCFRNYDATTEGLAPVRGRLQAQEEEEHLQDEEVWDALTDGFVPRGSPRPWMHPEAEAPDGTDPQLCEKEDEELAERSEHDSGINEEPLLTAEQVIEELEELMQSSPDPEADPEGDEDEEEEEDEEEDAEANAEGDSGSRGMEPIVLHELHTFSPTFNNNCSHEGLEQLTAGELAAAAGRAEAASRALSAELVAQLARRDELAFEKEVKTAFIGALLAVQGEQREQREAARRRRRDRGLSLQGGRPERGGHMPRKRFSMEGISSILHSGLRQTFGPAANEKQYLNTVIPYEKKGSPPSVEDLQMLTNILFAMKEGNEKVPTLLTDYILKVLCPT", "length": 393, "header": "tr|A0A1L1RVA3-1|A0A1L1RVA3_CHICK Isoform 1 of Fasciculation and elongation protein zeta 1 OS=Gallus gallus OX=9031 GN=FEZ1 PE=3 SV=2 CANONICAL=A0A1L1RVA3-1" }, "locus": { "chromosome": "24", "start_pos": 188893, "end_pos": 180967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059610.1", "url": "https://www.ensembl.org/id/ENSGALT00010059610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036406.1", "url": "https://www.ensembl.org/id/ENSGALP00010036406.1" } ] } }, { "isoform_ac": "A0A8V0ZZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZR3/entry", "sequence": { "sequence": "MEAPLVSLEEEFEEGPGDNGGVPRRTMDPALAELESFSTEMMSFKSMEDLVQEFDEKLTVCFRNYDATTEGLAPVRGRLQAQEEEEHLQDEEVWDALTDGFVPRGSPRPWMHPEAEAPDGTDPQLCEKEDEELAERSEHDSGINEEPLLTAEQVIEELEELMQSSPDPEADPEGDEDEEEEEDEEEDAEANAEGDSGSRGMEPIVLHELHTFSPTFNNNCSHEGLEQLTAGELAASRALSAELVAQLARRDELAFEKEVKTAFIGALLAVQGEQREQREAARRRRRDRGLSLQGGRPERGGHMPRKRFSMEGISSILHSGLRQTFGPAANEKQYLNTVIPYEKKGSPPSVEDLQMLTNILFAMKEGNEKVPTLLTDYILKVLCPT", "length": 385, "header": "tr|A0A8V0ZZR3-1|A0A1L1RVA3_CHICK Computationally mapped isoform of Fasciculation and elongation protein zeta 1 OS=Gallus gallus OX=9031 GN=FEZ1 PE=3 SV=1 CANONICAL=A0A1L1RVA3-1" }, "locus": { "chromosome": "24", "start_pos": 188893, "end_pos": 180967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059613.1", "url": "https://www.ensembl.org/id/ENSGALT00010059613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036408.1", "url": "https://www.ensembl.org/id/ENSGALP00010036408.1" } ] } }, { "isoform_ac": "A0A8V1A527-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A527/entry", "sequence": { "sequence": "MEAPLVSLEEEFEEGPGDNGGVPRRTMDPALAELESFSTEMMSFKSMEDLVQEFDEKLTVCFRNYDATTEGLAPVRGRLQAQEEEEHLQDEEVWDALTDGFVPRGSPRPWMHPEAEAPDGTDPQLCEKEDEELAERSEHDSGINEEPLLTAEQVIEELEELMQSSPDPEADPEGDEDEEEEEDEEEDAEANAEGDSGSRGMEPIVLHELHTFSPTFNNNCSHEGLEQLTAGELAAAAGRAEAASRALSAELVAQLARRDELAFEKEVKTAFIGALLAVQGEQREQREAARRRRRDRGLSLQGGRPERGGHMPRKRFSMEGISSILHSGLRQTFGPAANEKQVPFPPNLPKSVPFHPLLCTLVCAIFALFHPFNPT", "length": 375, "header": "tr|A0A8V1A527-1|A0A1L1RVA3_CHICK Computationally mapped isoform of Fasciculation and elongation protein zeta 1 OS=Gallus gallus OX=9031 GN=FEZ1 PE=3 SV=1 CANONICAL=A0A1L1RVA3-1" }, "locus": { "chromosome": "24", "start_pos": 187025, "end_pos": 180967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059607.1", "url": "https://www.ensembl.org/id/ENSGALT00010059607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036405.1", "url": "https://www.ensembl.org/id/ENSGALP00010036405.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of autophagosome assembly", "id": "GO:1902902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902902", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RVA3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RVA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RVA3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 393, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RVA3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RVA3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RWA6-1", "uniprot_ac": "A0A1L1RWA6", "uniprot_id": "A0A1L1RWA6_CHICK", "mass": { "chemical_mass": 38226.0, "monoisotopic_mass": 38226.0 }, "refseq": { "ac": "XP_003640428", "name": "protein shisa-8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640428" }, "gene_names": [ { "name": "SHISA8", "type": "recommended", "evidence": [ { "id": "A0A1L1RWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ] }, { "name": "SHISA8", "type": "synonym", "evidence": [ { "id": "XP_003640428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640428" } ] } ], "protein_names": [ { "name": "Shisa family member 8", "type": "synonym", "evidence": [ { "id": "A0A1L1RWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6/entry#names_and_taxonomy" } ] }, { "name": "protein shisa-8", "type": "synonym", "evidence": [ { "id": "XP_003640428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640428" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640428" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHISA8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6", "locus": {} } ], "crossref": [ { "id": "A0A1L1RWA6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RWA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000045762", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000045762", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857803", "url": "https://www.ncbi.nlm.nih.gov/gene/100857803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857803", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWWGKIS", "url": "https://omabrowser.org/oma/group/VWWGKIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWA6", "url": "https://www.orthodb.org/?gene=A0A1L1RWA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31774:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31774:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRSRGRMERSYVVGICCLVLLERSWGAEPGTGDGGNSSRAPAVEDTAPAPTEPTPGGDRCRGYYDVMGQWDPPFNCNAGIYQYCCGTCGYRFCCQFKARRLDQSGCSNYDTPNWVNTGQPPARVDESPEGPTRDKTNMIVYIICGVVAIMVLVGIFTKLGLEKAQGPQTEMTVSRTLTDLLKQPGHGPSEHIDGLMGSMQVQLGEGLPRGPPRNSTDKLPLNNAVDSTGVTPLGRPHGHSKRPPLGSSLSPPAPSYTAYTTLTAGESIPEDFYMRFGGPEVPPTSTLPFPTTEGSDSCPPPGVTKAKGLPKTPGGPAFPGGWEGGLPRGLRRPGPTTPLYGRAHRHLATNSKTEVTV", "length": 359, "header": "tr|A0A1L1RWA6-1|A0A1L1RWA6_CHICK Isoform 1 of Shisa family member 8 OS=Gallus gallus OX=9031 GN=SHISA8 PE=4 SV=2 CANONICAL=A0A1L1RWA6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6/entry", "sequence": { "sequence": "MAPRSRGRMERSYVVGICCLVLLERSWGAEPGTGDGGNSSRAPAVEDTAPAPTEPTPGGDRCRGYYDVMGQWDPPFNCNAGIYQYCCGTCGYRFCCQFKARRLDQSGCSNYDTPNWVNTGQPPARVDESPEGPTRDKTNMIVYIICGVVAIMVLVGIFTKLGLEKAQGPQTEMTVSRTLTDLLKQPGHGPSEHIDGLMGSMQVQLGEGLPRGPPRNSTDKLPLNNAVDSTGVTPLGRPHGHSKRPPLGSSLSPPAPSYTAYTTLTAGESIPEDFYMRFGGPEVPPTSTLPFPTTEGSDSCPPPGVTKAKGLPKTPGGPAFPGGWEGGLPRGLRRPGPTTPLYGRAHRHLATNSKTEVTV", "length": 359, "header": "tr|A0A1L1RWA6-1|A0A1L1RWA6_CHICK Isoform 1 of Shisa family member 8 OS=Gallus gallus OX=9031 GN=SHISA8 PE=4 SV=2 CANONICAL=A0A1L1RWA6-1" }, "locus": { "chromosome": "1", "start_pos": 49531545, "end_pos": 49525770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025424.1", "url": "https://www.ensembl.org/id/ENSGALT00010025424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014369.1", "url": "https://www.ensembl.org/id/ENSGALP00010014369.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 134, "start_aa": "Thr", "end_pos": 134, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr134", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": 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"start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857803", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of short-term neuronal synaptic plasticity", "id": "GO:0048172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048172", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "pmid": "" }, { "name": "dendritic spine membrane", "id": "GO:0032591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032591", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWA6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RWA6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RWA6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RWA6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWA6" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U276-1", "uniprot_ac": "A0A3Q2U276", "uniprot_id": "A0A3Q2U276_CHICK", "mass": { "chemical_mass": 35281.0, "monoisotopic_mass": 35281.0 }, "refseq": { "ac": "XP_046770869", "name": "protein FAM228B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770869" }, "gene_names": [ { "name": "FAM228", "type": "recommended", "evidence": [ { "id": "A0A3Q2U276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276" } ] }, { "name": "FAM228", "type": "synonym", "evidence": [ { "id": "XP_046770869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770869" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2U276", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276/entry#names_and_taxonomy" } ] }, { "name": "protein FAM228B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046770869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770869" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046770869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770869" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U276", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM228", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U276", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U276", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000044479", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421978", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28584:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28584:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046770869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RWM1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U276", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U276-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVRPLLYWKPVLRGELRSSSTINASPQAMRTADSSETIPQATSSPPAAELSQQKLCQRYPTAPARSNTANTFDCSRFFGKTNTSRFWLTQKDFYHVKAAPDESTDIITSAQSILDRENYFVKEVDRYLRHHDFLNLRKKEILYKKWLEDVSEPLLWKIEDKMDSQSREEIQKRREEQLSLYLNYCKKKGYVALEAYDPSEYDPLFLKTCTDCWKVSIPALQDPLLKTVQKKFIETSIIKQCETGRPCSTRELQKLPLLPLGRQHMDAIEWLKVPYTYIASELHRTRRLRVVDHHKDSENR", "length": 301, "header": "tr|A0A3Q2U276-1|A0A3Q2U276_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=FAM228 PE=3 SV=1 CANONICAL=A0A3Q2U276-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWM1/entry", "sequence": { "sequence": "MRTADSSETIPQATSSPPAAELSQQKLCQRYPTAPARSNTANTFDCSRFFGKTNTSRFWLTQKDFYHVKAAPDESTDIITSAQSILDRENYFVKEVDRYLRHHDFLNLRKKEILYKKWLEDVSEPLLWKIEDKMDSQSREEIQKRREEQLSLYLNYCKKKGYVALEAYDPSEYDPLFLKTCTDCWKVSIPALQDPLLKTVQKKFIETSIIKQCETGRPCSTRELQKLPLLPLGRQHMDAIEWLKVPYTYIASELHRTRRLRVVDHHKDSENR", "length": 272, "header": "tr|A0A1L1RWM1-1|A0A3Q2U276_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=FAM228 PE=3 SV=1 CANONICAL=A0A3Q2U276-1" }, "locus": { "chromosome": "3", "start_pos": 104054503, "end_pos": 104048837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020287.1", "url": "https://www.ensembl.org/id/ENSGALT00010020287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011797.1", "url": "https://www.ensembl.org/id/ENSGALP00010011797.1" } ] } }, { "isoform_ac": "A0A3Q2U276-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U276/entry", "sequence": { "sequence": "MNVRPLLYWKPVLRGELRSSSTINASPQAMRTADSSETIPQATSSPPAAELSQQKLCQRYPTAPARSNTANTFDCSRFFGKTNTSRFWLTQKDFYHVKAAPDESTDIITSAQSILDRENYFVKEVDRYLRHHDFLNLRKKEILYKKWLEDVSEPLLWKIEDKMDSQSREEIQKRREEQLSLYLNYCKKKGYVALEAYDPSEYDPLFLKTCTDCWKVSIPALQDPLLKTVQKKFIETSIIKQCETGRPCSTRELQKLPLLPLGRQHMDAIEWLKVPYTYIASELHRTRRLRVVDHHKDSENR", "length": 301, "header": "tr|A0A3Q2U276-1|A0A3Q2U276_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=FAM228 PE=3 SV=1 CANONICAL=A0A3Q2U276-1" }, "locus": { "chromosome": "3", "start_pos": 104054503, "end_pos": 104046782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020284.1", "url": "https://www.ensembl.org/id/ENSGALT00010020284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011794.1", "url": "https://www.ensembl.org/id/ENSGALP00010011794.1" } ] } }, { "isoform_ac": "A0A8V0Y2X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2X3/entry", "sequence": { "sequence": "MGCRGAGGGRGGIRPLFFPPRPLGSGRPPLGACPADREPSRCLEGVSSSSEQLERYPTAPARSNTANTFDCSRFFGKTNTSRFWLTQKDFYHVKAAPDESTDIITSAQSILDRENYFVKEVDRYLRHHDFLNLRKKEILYKKWLEDVSEPLLWKIEDKMDSQSREEIQKRREEQLSLYLNYCKKKGYVALEAYDPSEYDPLFLKTCTDCWKVSIPALQDPLLKTVQKKFIETSIIKQCETGRPCSTRELQKLPLLPLGRQHMDAIEWLKVPYTYIASELHRTRRLRVVDHHKDSENR", "length": 297, "header": "tr|A0A8V0Y2X3-1|A0A3Q2U276_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=FAM228 PE=3 SV=1 CANONICAL=A0A3Q2U276-1" }, "locus": { "chromosome": "3", "start_pos": 104054503, "end_pos": 104047213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020278.1", "url": "https://www.ensembl.org/id/ENSGALT00010020278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011791.1", "url": "https://www.ensembl.org/id/ENSGALP00010011791.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421978", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QQ68-1", "protein_name": "Protein FAM228B", "gene_name": "FAM228B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSYENDPITDKLPKLKSSREWLEPQPLSFMEVLAKEDVDTAIQSILYRENYIIKELDKCLKHHDFLNARRKEILYKRWVDHVADPLQKKIIEKVTSYKKIKKRRQEELDGFLKYVNKKGNAFIEHYDPKEYDPFYMNRENPNFLKVTIPPFRDPLKKAQYDKDDGKRILLQCETGKIYTMKEFKEVEKAKLHSRFPGISNSRHLMTPNEWIRLPPNYIESEFCKRSRLKIKVNFNESSFDLKPSVRTPHPEFQKEDKAVHYKF", "length": 264 }, "evidence": [ { "id": "A0A3Q2U276", "url": "https://omabrowser.org/oma/group/A0A3Q2U276/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R8F7-1", "protein_name": "Family with sequence similarity 228, member B", "gene_name": "Fam228b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"url": "https://omabrowser.org/oma/group/A0A3Q2U276/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q497Q6-1", "protein_name": "Protein FAM228B", "gene_name": "Fam228b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTMKNRSQDDMVTGTLPKLKSSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKELDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVHSHKNIKKRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYMSKEDPNFLKVIMPPFRDPLKKAQYDQDDEKRTLLQCETGKIYTMKEFKEIEKAQLHSRFPSISNSRQSMTPNGWLKVPMSYIESEFCKKSR", "length": 232 }, "evidence": [ { "id": "A0A3Q2U276", "url": "https://omabrowser.org/oma/group/A0A3Q2U276/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"uniprot_canonical_ac": "A0A1L1RWV1-1", "uniprot_ac": "A0A1L1RWV1", "uniprot_id": "A0A1L1RWV1_CHICK", "mass": { "chemical_mass": 19915.0, "monoisotopic_mass": 19915.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107055873", "type": "recommended", "evidence": [ { "id": "A0A1L1RWV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1" } ] }, { "name": "LOC107052660", "type": "synonym", "evidence": [ { "id": "A0A1L1RWV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1" } ] } ], "protein_names": [ { "name": "SUN domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A1L1RWV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWV1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055873", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000045507", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000045507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWV1", "url": "https://www.orthodb.org/?gene=A0A1L1RWV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RWV1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 182, "header": "tr|A0A1L1RWV1-1|A0A1L1RWV1_CHICK Isoform 1 of SUN domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107055873 PE=4 SV=2 CANONICAL=A0A1L1RWV1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1/entry", "sequence": { "sequence": "MTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 182, "header": "tr|A0A1L1RWV1-1|A0A1L1RWV1_CHICK Isoform 1 of SUN domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107055873 PE=4 SV=2 CANONICAL=A0A1L1RWV1-1" }, "locus": { "chromosome": "2", "start_pos": 81427462, "end_pos": 81425126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018590.1", "url": "https://www.ensembl.org/id/ENSGALT00010018590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010174.1", "url": "https://www.ensembl.org/id/ENSGALP00010010174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], 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adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RWV1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RWV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWV1" }, { "id": "PS51469", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUN", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 171, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RXQ1-1", "uniprot_ac": "A0A1L1RXQ1", "uniprot_id": "A0A1L1RXQ1_CHICK", "mass": { "chemical_mass": 67701.0, "monoisotopic_mass": 67701.0 }, "refseq": { "ac": "XP_003642151", "name": "cell division cycle protein 23 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642151" }, "gene_names": [ { "name": "CDC23", "type": "recommended", "evidence": [ { "id": "A0A1L1RXQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ] }, { "name": "CDC23", "type": "synonym", "evidence": [ { "id": "XP_003642151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642151" } ] } ], "protein_names": [ { "name": "Cyclosome subunit 8", "type": "recommended", "evidence": [ { "id": "A0A1L1RXQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle protein 23 homolog", "type": "synonym", "evidence": [ { "id": "XP_003642151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642151" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642151" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC23", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1", "locus": { "chromosome": "13", "start_pos": 17692104, "end_pos": 17709958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014131", "url": "https://www.ensembl.org/id/ENSGALG00010014131" } ] } } ], "crossref": [ { "id": "A0A1L1RXQ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RXQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007610", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771857", "url": "https://www.ncbi.nlm.nih.gov/gene/771857", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "423661", "url": "https://www.iedb.org/epitope/423661", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR007192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771857", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771857", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERCLYHS", "url": "https://omabrowser.org/oma/group/ERCLYHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RXQ1", "url": "https://www.orthodb.org/?gene=A0A1L1RXQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMT7", "url": "https://www.orthodb.org/?gene=A0A8V0YMT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPL0", "url": "https://www.orthodb.org/?gene=A0A8V0YPL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642151", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVGAVVGLGNADFSDLREIKKQLLSVAERSRERGLQHSGKWASELAFALEPLLLSELPPPPALTEEDARDLDAYTLAKSYFDLKEYDRAAYFLRGCKSQKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHKAQELDGFGLYLYGVVLRKLDLAKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQSLIDAGFSKSTYIISQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKPELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLNESEQAAQCYIKYIQDIYSCGEIVEHLEVSTAFRYLAQYYFKCKLWDEASACAQKCCSFNDTREEGKALLRQILQLRNQGETSSTEIATPFFLPASLSANSTPTRRVSPLNLSSVTP", "length": 586, "header": "tr|A0A1L1RXQ1-1|A0A1L1RXQ1_CHICK Isoform 1 of Cyclosome subunit 8 OS=Gallus gallus OX=9031 GN=CDC23 PE=1 SV=1 CANONICAL=A0A1L1RXQ1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1/entry", "sequence": { "sequence": "MAAVGAVVGLGNADFSDLREIKKQLLSVAERSRERGLQHSGKWASELAFALEPLLLSELPPPPALTEEDARDLDAYTLAKSYFDLKEYDRAAYFLRGCKSQKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHKAQELDGFGLYLYGVVLRKLDLAKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQSLIDAGFSKSTYIISQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKPELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLNESEQAAQCYIKYIQDIYSCGEIVEHLEVSTAFRYLAQYYFKCKLWDEASACAQKCCSFNDTREEGKALLRQILQLRNQGETSSTEIATPFFLPASLSANSTPTRRVSPLNLSSVTP", "length": 586, "header": "tr|A0A1L1RXQ1-1|A0A1L1RXQ1_CHICK Isoform 1 of Cyclosome subunit 8 OS=Gallus gallus OX=9031 GN=CDC23 PE=1 SV=1 CANONICAL=A0A1L1RXQ1-1" }, "locus": { "chromosome": "13", "start_pos": 17703265, "end_pos": 17693474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033941.1", "url": "https://www.ensembl.org/id/ENSGALT00010033941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019948.1", "url": "https://www.ensembl.org/id/ENSGALP00010019948.1" } ] } }, { "isoform_ac": "A0A8V0YMT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT7/entry", "sequence": { "sequence": "MAAVGAVVGLGNADFSDLREIKKQLLSVAERSRERGLQHSGKWASELAFALEPLLLSELPPPPALTEEDARDLDAYTLAKSYFDLKEYDRAAYFLRGCKSQKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHKAQELDGFGLYLYGVVLRKLDLAKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQSLIDAGFSKSTYIISQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKPELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLNESEQAAQCYIKYIQDIYSCGEIVEHLEVSTAFRYLAQYYFKCKLWDEASACAQKCCSFNDTREEGKALLRQILQLRNQGETSSTEIATPFFLPASLSANSTPTRRVSPLNLSSVTP", "length": 546, "header": "tr|A0A8V0YMT7-1|A0A1L1RXQ1_CHICK Computationally mapped isoform of Cyclosome subunit 8 OS=Gallus gallus OX=9031 GN=CDC23 PE=1 SV=1 CANONICAL=A0A1L1RXQ1-1" }, "locus": { "chromosome": "13", "start_pos": 17703265, "end_pos": 17693474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033934.1", "url": "https://www.ensembl.org/id/ENSGALT00010033934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019946.1", "url": "https://www.ensembl.org/id/ENSGALP00010019946.1" } ] } }, { "isoform_ac": "A0A8V0YPL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL0/entry", "sequence": { "sequence": "MQGNSVGDSCQPEAFCWASELAFALEPLLLSELPPPPALTEEDARDLDAYTLAKSYFDLKEYDRAAYFLRGCKSQKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHKAQELDGFGLYLYGVVLRKLDLAKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQSLIDAGFSKSTYIISQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKPELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLNESEQAAQCYIKYIQDIYSCGEIVEHLEVSTAFRYLAQYYFKCKLWDEASACAQKCCSFNDTREEGKALLRQILQLRNQGETSSTEIATPFFLPASLSANSTPTRRVSPLNLSSVTP", "length": 560, "header": "tr|A0A8V0YPL0-1|A0A1L1RXQ1_CHICK Computationally mapped isoform of Cyclosome subunit 8 OS=Gallus gallus OX=9031 GN=CDC23 PE=1 SV=1 CANONICAL=A0A1L1RXQ1-1" }, "locus": { "chromosome": "13", "start_pos": 17709759, "end_pos": 17693474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033946.1", "url": "https://www.ensembl.org/id/ENSGALT00010033946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019952.1", "url": "https://www.ensembl.org/id/ENSGALP00010019952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Mass spectral data for 64 eluted peptides and structural modeling define peptide binding preferences for class I alleles in two chicken MHC-B haplotypes associated with opposite responses to Marek's disease.", "journal": "Immunogenetics", "date": "2008-09", "authors": "Sherman Mark A, Goto Ronald M, Moore Roger E, Hunt Henry D, Lee Terry D, Miller Marcia M", "evidence": [ { "database": "IEDB", "id": "423661", "url": "https://www.iedb.org/epitope/423661" } ], "reference": [ { "type": "PubMed", "id": "18612635", "url": "https://glygen.org/publication/PubMed/18612635" } ] } ], "pathway": [ { "id": "gga:771857", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771857", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-GGA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-GGA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-GGA-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-GGA-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-GGA-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AB31-1", "protein_name": "Cell division cycle protein 23 homolog", "gene_name": "Cdc23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAANSSVVSVAAAATTVPGVSTVADFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLSELQPPPPLTEEDAQDVDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSRKHQARGLDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGETVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTSDTPGTFFLPASLSANNTPTRRVSPLNLSSVTP", "length": 597 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A4R8-1", "protein_name": "Cell division cycle protein 23 homolog", "gene_name": "CDC23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASSSIVSVAPTASSVPVLPSSCDFSNLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLSELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASACAQKCCAFNDTREEGKALLRQILQLRNQGETPSTEIPAPFFLPASLSANNTPTRRVSPLNLSSVTP", "length": 597 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RH91-1", "protein_name": "Cell division cycle protein 23 homolog", "gene_name": "CDC23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASPSVVPVTAVMPVLSSSGDFSNLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLSELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPSTEMPAPFFLPASLSANNTPTRRVSPLNLSSVTP", "length": 594 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P16522-1", "protein_name": "Anaphase-promoting complex subunit CDC23", "gene_name": "CDC23", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNDDSQDKIIHDIRIQLRKAATELSRWKLYGSSKWAAEALAGLAEAIDVDQTHSLADESPLRNKQGVPKQMFEIPQNGFGLSETEYDLYLLGSTLFDAKEFDRCVFFLKDVTNPYLKFLKLYSKFLSWDKKSQESMENILTTGKFTDEMYRANKDGDGSGNEDINQSGHQRANLKMVSNEHESQSNISSILKEINTFLESYEIKIDDDEADLGLALLYYLRGVILKQEKNISKAMSSFLKSLSCYSFNWSCWLELMDCLQKVDDALLLNNYLYQNFQFKFSENLGSQRTIEFNIMIKFFKLKVFEELNGQLEDYFEDLEFLLQVFPNFTFLKAYNATISYNNLDYVTAESRFDDIVKQDPYRLNDLETYSNILYVMQKNSKLAYLAQFVSQIDRFRPETCCIIANYYSARQEHEKSIMYFRRALTLDKKTTNAWTLMGHEFVELSNSHAAIECYRRAVDICPRDFKAWFGLGQAYALLDMHLYSLYYFQKACTLKPWDRRIWQVLGECYSKTGNKVEAIKCYKRSIKASQTVDQNTSIYYRLAQLYEELEDLQECKKFMMKCVDVEELLEGIVTDETVKARLWLAIFEIKAGNYQLAYDYAMGVSSGTSQEIEEARMLARECRRHM", "length": 626 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q86B11-1", "protein_name": "Anaphase-promoting complex subunit 8", "gene_name": "anapc8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQIKIELIKSINDLNSRGLLLSSKWSSEQLNGLSPTILATPLTNEEQLSIISQPSISSPPIGSNEYYKYILAKNYFDLKEYRRCSDVLIDCNKYQLPIFLRSYATYLAIEKRREEDIIEQQAQQQQQQQQAQQQAQQAQQESQQNDKNNDTNNNNKTDQQQQQQQQQKIEQCQEFKQLFQFYKKLYIENKKDMDGFLLYFYSMLLKKQRDFTMARKVLIESVHKYPCNWSAWSDLSSLCSDSADIIMQLSLPDHFMKDFFLAHFKLELQQNNESLVIYQQLSRTLFTQSTYILAQTAIGNYNLRAYDIGEELFERLIELEPNRLENIDIYSNILYVRDKKASLSMLAHKAMKIEKYCPETCCIIGNYYSLKLEHDKAILYFQRALKLNDRYLSAWTLIGHEFLEIKNVSAAINAYRKAVDINPRDYRAWYGLGQTYQLLKLPLYSLYYFKKATTLRPYDPRMWCAAGGCYEFIERIPEAIKCYERAEENYDRERVAINKLAKLYQEIQNNEKAAFYYKKNLYYCDQEKIDGQEIIDALLFLANFYKNQNQTQSEQYCLRLLDYAGPEKEEAKSILREIHSKSKLSSKSKPK", "length": 592 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BGZ4-1", "protein_name": "Cell division cycle protein 23 homolog", "gene_name": "Cdc23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAANSSVVSVAAAATAVPGVSTVADFSDLQEIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLSELQPPPPLTEEDAQDVDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSRKHQARGLDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKKALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGETVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTSDTPGTFFLPASLSANNTPTRRVSPLNLSSVTP", "length": 597 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7L8-1", "protein_name": "Cyclosome subunit 8", "gene_name": "Cdc23", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMQKFFSVLLPDVKRELRRGIIECSKRGLLHSTKWLAEMHHGLADVHIDNEAPDEDRTFSECQLEGIAPEEYSDYFLAKSYYDVREYDRAAHAVRNCESSVPRFLHFYSSYMAREKRRLDSTTDQANLHEPNQMRDLADLLATLRMEYGKSRLDGYGIYLYGVVLKALNLNQAAEQMLVQAIRLVPMLWSAYLELSPLIMEKKKLLSLQLGGHWMRHFFMAHTYLELYLNDDGLKIYEDLQASGFSKSIYLIAQMALVYHNKRDVDKAIELYQALLESDPYRLDNVDTYSNLLFVKEMKTEMAQLAHKAVSINKYRPETCCVIGNYYSIRCDHQVAISYFQRALKLNPKYLAAWTLMGHEFMELKNTNAAIQSYRKAVEVNKRDYRAWYGLGQAYEIIKMHYYSLYYFKIAHQLRPYDSRMLVALGETYEKLDKCENAVKCYWKAIDVGDIEGIAMYKLANLHEKLGDHETAVHCYIMYCEDERAATDKQSLYQGFITLANYYEKKGEYERAAYYAYKCLDSEDRKMEAKALLKTIDWKRNAEGQKKVKTSTAVANADTSSEDEMEWELQDVRVRVPITSIATTTTSTTTVAAESASSSSLISLRPDRNLIQGMRRSQSSRTSLTAPASGTTTTPSATAVTMSTEETPGTSGGPSNPPEQAPSDDNSSMEISSVSID", "length": 678 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9STS3-1", "protein_name": "Anaphase-promoting complex subunit 8", "gene_name": "APC8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSKECCRNEIRAAIRQLSDRCLYSAAKWAGEQLVGIEQDPSNFTPANTRFQRGSSSIRRRFSTNESISTPLPSVGFSQAATPLPEEDEAIDGDIYLLAKSYFDCREYRRASHMLRDQVSKKSLFLRYYALYLAGEKRKEEEMIELEGPLGKSDAINRELVSLERDLSALRRTGAIDSFGLYLYGVVLKEKGNESLARASLVESVNSYPWNWSAWSELQSLCTSIEILNSLNLNNHWMKEFFLGNAYQELRMHTESLAKYEYLQGIFSFSNYIQAQTAKAQYSLREFDQVEIMFEELLRNDPYRVEDMDLYSNVLYAKEACAALSYLAHKVFLTDKYRPESCCIIGNYYSLKGQHEKAVMYFRRALKLNKKYLSAWTLMGHEYVEMKNTPAAIDAYRRAVDINPTDYRAWYGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKCYQTEQLYMLEEAIKCYKRAVNCTDTEGIALNQLAKLHQKLGRNEEAAYYFEKDLERMDAEGLEGPNMFEALVFLATHFKNHKKFEEAEVYCTRLLDYSGPEKEKAKSLLRGIRMAQTGFPSMDLEHFPI", "length": 579 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UJX2-1", "protein_name": "Cell division cycle protein 23 homolog", "gene_name": "CDC23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP", "length": 597 }, "evidence": [ { "id": "A0A1L1RXQ1", "url": "https://omabrowser.org/oma/group/A0A1L1RXQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RXQ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 586, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RXQ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RXQ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RXQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RXQ1" }, { "id": "PF04049", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04049" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cdc23", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 259, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 369, "end_pos": 371 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 580, "end_pos": 582 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RY66-1", "uniprot_ac": "A0A1L1RY66", "uniprot_id": "A0A1L1RY66_CHICK", "mass": { "chemical_mass": 64402.0, "monoisotopic_mass": 64402.0 }, "refseq": { "ac": "XP_040543453", "name": "Meckel syndrome type 1 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543453" }, "gene_names": [ { "name": "MKS1", "type": "recommended", "evidence": [ { "id": "A0A1L1RY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY66" } ] }, { "name": "MKS1", "type": "synonym", "evidence": [ { "id": "XP_040543453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543453" } ] } ], "protein_names": [ { "name": "MKS transition zone complex subunit 1", "type": "synonym", "evidence": [ { "id": "A0A1L1RY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY66/entry#names_and_taxonomy" } ] }, { "name": "Meckel syndrome type 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040543453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543453" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"length": 484, "header": "tr|A0A8V1AKL2-1|A0A1L1RY66_CHICK Computationally mapped isoform of MKS transition zone complex subunit 1 OS=Gallus gallus OX=9031 GN=MKS1 PE=4 SV=1 CANONICAL=A0A1L1RY66-1" }, "locus": { "chromosome": "19", "start_pos": 689000, "end_pos": 679945, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071357.1", "url": "https://www.ensembl.org/id/ENSGALT00010071357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044048.1", "url": "https://www.ensembl.org/id/ENSGALP00010044048.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RY66", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY66" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RY66", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY66" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RY66", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY66" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": 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"MEDVGSSVNADAEVRKLQELVKKLEKQNEQLRSRHGALPAAPASPKRLLSGGASPSPPAAAASPSPSDGRCLSPRAAARRQPPEEPGGGESDGLLDDAAPLRPDELERLAGCEEDETGWLYTSPKKRLTPMQKCVSPLVWCRQVLDYPSPDIECAKKSLIHRLEQTMSAMKRQSLYNSPFSAVSYASSYSPNTSSPYSSGFNSPSSTPVKSALVKQFISPGTSGHLKSSADRNPPLSPQSSVDSELSASEMDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAASASRRSSGSSCNSTRRGTFSDQELDAQSLEDEEDGTHHTVHPAVSRFSPSPRSSPWPSPKQSPRNSPRSRSPARSIEYSRVSPQPMISRLQQPRLSLQGHPTDMQTSNVKSEEKLRRSLPNLSRTSNIQAESVKNSRSDSNFQVPNGGIPRIQPQASATLQRQKNLPRAAFKTKQFLQTPSAKGVPSSSKFRSPAAPSPLALRQPVKAFSNHGPGSVAPLEATQLTHSSSSPGPLAAQSSGLPGPASGVNSTTLTRPAGTVGMRSSLPRPSAPSTGGIPVPRSKLAQPVRRSLPAPKTYSNMKDESWKDGCY", "length": 597, "header": "tr|A0A3Q2U2B3-1|A0A3Q2U2B3_CHICK Isoform 1 of SLAIN motif family member 2 OS=Gallus gallus OX=9031 GN=SLAIN2 PE=3 SV=1 CANONICAL=A0A3Q2U2B3-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RY85-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RY85/entry", "sequence": { "sequence": "MEDVGSSVNADAEVRKLQELVKKLEKQNEQLRSRHGALPAAPASPKRLLSGGASPSPPAAAASPSPSDGRCLSPRAAARRQPPEEPGGGESDGLLDDAAPLRPDELERLAGCEEDETGWLYTSPKKRLTPMQKCVSPLVWCRQVLDYPSPDIECAKKSLIHRLEQTMSAMKRQSLYNSPFSAVSYASSYSPNTSSPYSSGFNSPSSTPVKSALVKQFISPGTSGHLKSSADRNPPLSPQSSVDSELSASEMDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAASASRRSSGSSCNSTRRGTFSDQELDAQSLEDEEDGTHHTVHPAVSRFSPSPRSSPWPSPKQSPRNSPRSRSPARSIEYSRVSPQPMISRLQQPRLSLQGHPTDMQTSNVKSEEKLRRSLPNLSRTSNIQAESVKNSRSDSNFQVPNGGIPRIQPQASANHYLLPKPTAT", "length": 454, "header": "tr|A0A1L1RY85-1|A0A3Q2U2B3_CHICK Computationally mapped isoform of SLAIN motif family member 2 OS=Gallus gallus OX=9031 GN=SLAIN2 PE=3 SV=1 CANONICAL=A0A3Q2U2B3-1" }, "locus": { "chromosome": "4", "start_pos": 66003178, "end_pos": 65977574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040484.1", "url": "https://www.ensembl.org/id/ENSGALT00010040484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023496.1", "url": "https://www.ensembl.org/id/ENSGALP00010023496.1" } ] } }, { "isoform_ac": "A0A3Q2U2B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3/entry", "sequence": { "sequence": "MEDVGSSVNADAEVRKLQELVKKLEKQNEQLRSRHGALPAAPASPKRLLSGGASPSPPAAAASPSPSDGRCLSPRAAARRQPPEEPGGGESDGLLDDAAPLRPDELERLAGCEEDETGWLYTSPKKRLTPMQKCVSPLVWCRQVLDYPSPDIECAKKSLIHRLEQTMSAMKRQSLYNSPFSAVSYASSYSPNTSSPYSSGFNSPSSTPVKSALVKQFISPGTSGHLKSSADRNPPLSPQSSVDSELSASEMDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAASASRRSSGSSCNSTRRGTFSDQELDAQSLEDEEDGTHHTVHPAVSRFSPSPRSSPWPSPKQSPRNSPRSRSPARSIEYSRVSPQPMISRLQQPRLSLQGHPTDMQTSNVKSEEKLRRSLPNLSRTSNIQAESVKNSRSDSNFQVPNGGIPRIQPQASATLQRQKNLPRAAFKTKQFLQTPSAKGVPSSSKFRSPAAPSPLALRQPVKAFSNHGPGSVAPLEATQLTHSSSSPGPLAAQSSGLPGPASGVNSTTLTRPAGTVGMRSSLPRPSAPSTGGIPVPRSKLAQPVRRSLPAPKTYSNMKDESWKDGCY", "length": 597, "header": "tr|A0A3Q2U2B3-1|A0A3Q2U2B3_CHICK Isoform 1 of SLAIN motif family member 2 OS=Gallus gallus OX=9031 GN=SLAIN2 PE=3 SV=1 CANONICAL=A0A3Q2U2B3-1" }, "locus": { "chromosome": "4", "start_pos": 66003178, "end_pos": 65977542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040601.1", "url": "https://www.ensembl.org/id/ENSGALT00010040601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023575.1", "url": "https://www.ensembl.org/id/ENSGALP00010023575.1" } ] } }, { "isoform_ac": "F1NZZ4-1", "url": "https://www.uniprot.org/uniprotkb/F1NZZ4/entry", "sequence": { "sequence": "MEDVGSSVNADAEVRKLQELVKKLEKQNEQLRSRHGALPAAPASPKRLLSGGASPSPPAAAASPSPSDGRCLSPRAAARRQPPEEPGGGESDGLLDDAAPLRPDELERLAGCEEDETGWLYTSPKKRLTPMQKCVSPLVWCRQVLDYPSPDIECAKKSLIHRLEQTMSAMKRQSLYNSPFSAVSYASSYSPNTSSPYSSGFNSPSSTPVKSALVKQFISPGTSGHLKSSADRNPPLSPQSSVDSELSASEMDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAASASRRSSGSSCNSTRRGTFSDQELDAQSLEDEEDGTHHTVHPAVSRFSPSPRSSPWPSPKQSPRNSPRSRSPARSIEYSRVSPQPMISRLQQPRLSLQGHPTDMQTSNVKSEEKLRRSLPNLSRTSNIQAESVKNSRSDSNFQVPNGGIPRIQPQASAIPSSSKFRSPAAPSPLALRQPVKAFSNHGPGSVAPLEATQLTHSSSSPGPLAAQSSGLPGPASGVNSTTLTRPAGTVGMRSSLPRPSAPSTGGIPVPRSKLAQPVRRSLPAPKTYSNMKDESWKDGCY", "length": 571, "header": "tr|F1NZZ4-1|A0A3Q2U2B3_CHICK Computationally mapped isoform of SLAIN motif family member 2 OS=Gallus gallus OX=9031 GN=SLAIN2 PE=3 SV=2 CANONICAL=A0A3Q2U2B3-1" }, "locus": { "chromosome": "4", "start_pos": 66003178, "end_pos": 65977542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040640.1", "url": "https://www.ensembl.org/id/ENSGALT00010040640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023605.1", "url": "https://www.ensembl.org/id/ENSGALP00010023605.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422766", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422766", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2B3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2B3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U2B3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 597, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U2B3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U2B3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 535, "end_pos": 537 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RYD1-1", "uniprot_ac": "A0A1L1RYD1", "uniprot_id": "A0A1L1RYD1_CHICK", "mass": { "chemical_mass": 12301.0, "monoisotopic_mass": 12301.0 }, "refseq": { "ac": "NP_001264904", "name": "scale keratin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904" }, "gene_names": [ { "name": "LOC121107561", "type": "recommended", "evidence": [ { "id": "A0A1L1RYD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1" } ] }, { "name": "LOC100859722", "type": "synonym", "evidence": [ { "id": "NP_001264904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904" } ] }, { "name": "LOC121112087", "type": "synonym", "evidence": [ { "id": "A0A1L1RYD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A1L1RYD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1/entry#names_and_taxonomy" } ] }, { "name": "scale keratin-like", "type": "synonym", "evidence": [ { "id": "NP_001264904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904" } ] } ], "function": [ { "annotation": "VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Nov 16, 2021 this sequence version replaced NP_001264904.1. Sequence Note:.", "evidence": [ { "database": "RefSeq", "id": "NP_001264904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RYD1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121107561", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1", "locus": {} } ], "crossref": [ { "id": "121107561", "url": "https://www.ncbi.nlm.nih.gov/gene/121107561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859722", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RYD1", "url": "https://www.orthodb.org/?gene=A0A1L1RYD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264904", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RYD1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RYD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCALPRYSRKLWDTCGPC", "length": 121, "header": "tr|A0A1L1RYD1-1|A0A1L1RYD1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107561 PE=3 SV=1 CANONICAL=A0A1L1RYD1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RYD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYD1/entry", "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCALPRYSRKLWDTCGPC", "length": 121, "header": "tr|A0A1L1RYD1-1|A0A1L1RYD1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107561 PE=3 SV=1 CANONICAL=A0A1L1RYD1-1" }, "locus": { "chromosome": "25", "start_pos": 1452449, "end_pos": 1452087, "strand": "-", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RYS1-1", "uniprot_ac": "A0A1L1RYS1", "uniprot_id": "A0A1L1RYS1_CHICK", "mass": { "chemical_mass": 33795.0, "monoisotopic_mass": 33795.0 }, "refseq": {}, "gene_names": [ { "name": "PDCD1", "type": "recommended", "evidence": [ { "id": "A0A1L1RYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYS1" } ] } ], "protein_names": [ { "name": "Programmed cell death 1", "type": "synonym", "evidence": [ { "id": "A0A1L1RYS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYS1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", 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glycosylation and translocation to plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RYS1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RYS1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYS1" } ], "pmid": "" }, { "name": "negative regulation of immune response", "id": "GO:0050777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050777", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RYS1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RYS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RYS1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 304, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RYS1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RYS1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 85, "end_pos": 87 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZ25-1", "uniprot_ac": "A0A1L1RZ25", "uniprot_id": "A0A1L1RZ25_CHICK", "mass": { "chemical_mass": 26691.0, "monoisotopic_mass": 26691.0 }, "refseq": { "ac": "NP_001186597", "name": "leucine-rich repeat-containing protein 57", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186597" }, "gene_names": [ { "name": "LRRC57", "type": "recommended", "evidence": [ { "id": "A0A1L1RZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25" } ] }, { "name": "LRRC57", "type": "synonym", "evidence": [ { "id": "NP_001186597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186597" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 57", "type": "recommended", "evidence": [ { "id": "A0A1L1RZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 57", "type": "synonym", "evidence": [ { "id": "NP_001186597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186597" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01006093.1, HAEL01013431.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Dec 11, 2010 this sequence version replaced XP_421160.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001186597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186597" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25", "locus": { "chromosome": "5", "start_pos": 25240197, "end_pos": 25257252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019635", "url": "https://www.ensembl.org/id/ENSGALG00010019635" } ] } } ], "crossref": [ { "id": "A0A1L1RZ25", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RZ25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009112", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423236", "url": "https://www.ncbi.nlm.nih.gov/gene/423236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423236", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423236", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYMERYT", "url": "https://omabrowser.org/oma/group/AYMERYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZ25", "url": "https://www.orthodb.org/?gene=A0A1L1RZ25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA54", "url": "https://www.orthodb.org/?gene=A0A8V0ZA54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZAY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBN3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZ25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNSALKAHLETAQKTGVFQLTGKGLTEFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 238, "header": "tr|A0A1L1RZ25-1|A0A1L1RZ25_CHICK Isoform 1 of Leucine-rich repeat-containing protein 57 OS=Gallus gallus OX=9031 GN=LRRC57 PE=1 SV=1 CANONICAL=A0A1L1RZ25-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25/entry", "sequence": { "sequence": "MGNSALKAHLETAQKTGVFQLTGKGLTEFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 238, "header": "tr|A0A1L1RZ25-1|A0A1L1RZ25_CHICK Isoform 1 of Leucine-rich repeat-containing protein 57 OS=Gallus gallus OX=9031 GN=LRRC57 PE=1 SV=1 CANONICAL=A0A1L1RZ25-1" }, "locus": { "chromosome": "5", "start_pos": 25256613, "end_pos": 25253393, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047389.1", "url": "https://www.ensembl.org/id/ENSGALT00010047389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028080.1", "url": "https://www.ensembl.org/id/ENSGALP00010028080.1" } ] } }, { "isoform_ac": "A0A8V0ZA54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA54/entry", "sequence": { "sequence": "GLPALRVSKGGGKRGLRRFRREPRRPPDFVGIGTWLRRGSPRRFWGLAVLRPVARCGLCRRELREFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 275, "header": "tr|A0A8V0ZA54-1|A0A8V0ZA54_CHICK Computationally mapped isoform of Leucine rich repeat containing 57 OS=Gallus gallus OX=9031 GN=LRRC57 PE=1 SV=1 CANONICAL=A0A1L1RZ25-1" }, "locus": { "chromosome": "5", "start_pos": 25257223, "end_pos": 25253393, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047369.1", "url": "https://www.ensembl.org/id/ENSGALT00010047369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028069.1", "url": "https://www.ensembl.org/id/ENSGALP00010028069.1" } ] } }, { "isoform_ac": "A0A8V0ZAY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY0/entry", "sequence": { "sequence": "EIQHCAVKKKFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 220, "header": "tr|A0A8V0ZAY0-1|A0A8V0ZAY0_CHICK Computationally mapped isoform of Leucine rich repeat containing 57 OS=Gallus gallus OX=9031 GN=LRRC57 PE=1 SV=1 CANONICAL=A0A1L1RZ25-1" }, "locus": { "chromosome": "5", "start_pos": 25256263, "end_pos": 25253393, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047374.1", "url": "https://www.ensembl.org/id/ENSGALT00010047374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028071.1", "url": "https://www.ensembl.org/id/ENSGALP00010028071.1" } ] } }, { "isoform_ac": "A0A8V0ZBN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN3/entry", "sequence": { "sequence": "MGNSALKAHLETAQKTGVFQLTGKGLTEFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKLQRRSLRDFVLVVCIPGKKS", "length": 245, "header": "tr|A0A8V0ZBN3-1|A0A8V0ZBN3_CHICK Computationally mapped isoform of Leucine-rich repeat-containing protein 57 OS=Gallus gallus OX=9031 GN=LRRC57 PE=1 SV=1 CANONICAL=A0A1L1RZ25-1" }, "locus": { "chromosome": "5", "start_pos": 25256613, "end_pos": 25253353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047380.1", "url": "https://www.ensembl.org/id/ENSGALT00010047380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028075.1", "url": "https://www.ensembl.org/id/ENSGALP00010028075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423236", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423236", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G775-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMSQGVPARAEALGERLRRARVPGVPWRSLLCAERELSRSARMGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPQLIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNLLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSILDTVGELQAIELNLNQNQISQISVKISCCPRLKVLRLEENCLELSMLPQSILNDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 281 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SI25-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "LRRC57", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSSNKIESLPPMIIGKFTLLKSLSLNNNRLTVLPDELCHLKKLETLSLNNNHLRELPSTFGQLSALKTLSISGNQLRALPPQLCSLRHLDVVDLSKNQIRSIPDIVGELQVIELNLNQNQISQISVKISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FVI3-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQISVRISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DHL5-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "lrrc57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGNSALKAHLETSQKTGVFQLTGKGLTEFPEDLQKLTANLRTVDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVPAEVAELQAIEINLNQNQISSVTQEVSRTPRLKVLRLEENCLELSSIPLSILTDSQVSLLSVEGNLFEVKKMRDLEGYDKYMERFTATKKKFA", "length": 238 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D1G5-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKFRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W3T9-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Dmel\\CG3040", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNKQIKQQLETAQKTGILKISLQRLQEFPLQLRAYPNVLKTLDLSENRFERVPDELGKLTLLKHLNLSGNRLVELNEVVGELAKLEVLLLMDNMLTRLPKTLANCTHLKTVNLSNNQLKEFPSMLCGLKQLDVLDLSRNKITDVPADVGGLFVTELNLNQNQISSLAEEVADCPKLKTLRLEENCLQAAAFTPKILKDSKICNLAVDGNLFNSKQFTDLDGYDVYMERYTAVRKKMF", "length": 238 }, "evidence": [ { "id": "A0A1L1RZ25", "url": "https://omabrowser.org/oma/group/A0A1L1RZ25/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ25", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZ57-1", "uniprot_ac": "A0A1L1RZ57", "uniprot_id": "A0A1L1RZ57_CHICK", "mass": { "chemical_mass": 77153.0, "monoisotopic_mass": 77153.0 }, "refseq": { "ac": "XP_025009183", "name": "kyphoscoliosis peptidase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009183" }, "gene_names": [ { "name": "KY", "type": "recommended", "evidence": [ { "id": "A0A1L1RZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" } ] }, { "name": "KY", "type": "synonym", "evidence": [ { "id": "XP_025009183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009183" } ] } ], "protein_names": [ { "name": "Kyphoscoliosis peptidase", "type": "synonym", "evidence": [ { "id": "A0A1L1RZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57/entry#names_and_taxonomy" } ] }, { "name": "kyphoscoliosis peptidase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025009183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009183" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009183" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KY", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57", "locus": { "chromosome": "9", "start_pos": 3345903, "end_pos": 3367567, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024546", "url": "https://www.ensembl.org/id/ENSGALG00010024546" } ] } } ], "crossref": [ { "id": "A0A1L1RZ57", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RZ57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000044975", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769840", "url": "https://www.ncbi.nlm.nih.gov/gene/769840", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769840", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769840", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFTERQG", "url": "https://omabrowser.org/oma/group/WFTERQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZ57", "url": "https://www.orthodb.org/?gene=A0A1L1RZ57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TVX1", "url": "https://www.orthodb.org/?gene=A0A3Q2TVX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT23", "url": "https://www.orthodb.org/?gene=A0A8V0ZT23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY75", "url": "https://www.orthodb.org/?gene=A0A8V0ZY75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46333:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46333:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025009183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009183", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTERGSSARRQLGGGPAAMGTVELKDGANAVAINLLLIVRPERKGQRDGVTDGAGLQDDGNGNGRPQPPPKRDLSGQQDPKEPHKQKQTVTSYTNEGTHVTVEIHPKGTSPQFFKKLSFGKGPRRVPSLRGQDNKAFERTEAPRPPSTKDLHVYPWDKSSLKSLAVDLQKFEKLDAYALKVNTKGSVEELVQTLLKQARTDLEKVRVIWMWICHHIEYDVVGFHNKSLRLCKPTDVLRTGKSVCEGYAGLFQQMCSVAGIQCMKLSGYSKGYGYKIGQTFQGNSDHAWNAVYLDGRWHLLDSTWGSGTVDDALTKFTFKYNEFYFLTHPALFVNNHFPDNSNWQLLKPTLTLKQFESNLQHNSDFYNLGLLAAHPQTALIQTENGTATISVECRPSTLFTFKLEGTDEHGLLTLRKQGMKLELYPQKTGRQELQIFARPSKSTEDVYTCVLEYIVECKSVDKSRCFPKDLHQPVGPSWFTEKQGFLRPSHPDPIIHTNDGRCSLTFTLGKDISILASLHADSSSLSEEMSRQHIMQIHRGNQVEFKVHLPHAGSFVLKFFTKKKSDPGSYSFIFNYLITCLNTEVKWPAFPLRYSKWAEGYELLEPLSRLLPANRNVQFKLKMQGISKVLVQAGDTYTLTLSRDGFWEGTCNTAGCTELFVMVHENANHSYYSHILKYDVETQ", "length": 684, "header": "tr|A0A1L1RZ57-1|A0A1L1RZ57_CHICK Isoform 1 of Kyphoscoliosis peptidase OS=Gallus gallus OX=9031 GN=KY PE=4 SV=1 CANONICAL=A0A1L1RZ57-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57/entry", "sequence": { "sequence": "MVTERGSSARRQLGGGPAAMGTVELKDGANAVAINLLLIVRPERKGQRDGVTDGAGLQDDGNGNGRPQPPPKRDLSGQQDPKEPHKQKQTVTSYTNEGTHVTVEIHPKGTSPQFFKKLSFGKGPRRVPSLRGQDNKAFERTEAPRPPSTKDLHVYPWDKSSLKSLAVDLQKFEKLDAYALKVNTKGSVEELVQTLLKQARTDLEKVRVIWMWICHHIEYDVVGFHNKSLRLCKPTDVLRTGKSVCEGYAGLFQQMCSVAGIQCMKLSGYSKGYGYKIGQTFQGNSDHAWNAVYLDGRWHLLDSTWGSGTVDDALTKFTFKYNEFYFLTHPALFVNNHFPDNSNWQLLKPTLTLKQFESNLQHNSDFYNLGLLAAHPQTALIQTENGTATISVECRPSTLFTFKLEGTDEHGLLTLRKQGMKLELYPQKTGRQELQIFARPSKSTEDVYTCVLEYIVECKSVDKSRCFPKDLHQPVGPSWFTEKQGFLRPSHPDPIIHTNDGRCSLTFTLGKDISILASLHADSSSLSEEMSRQHIMQIHRGNQVEFKVHLPHAGSFVLKFFTKKKSDPGSYSFIFNYLITCLNTEVKWPAFPLRYSKWAEGYELLEPLSRLLPANRNVQFKLKMQGISKVLVQAGDTYTLTLSRDGFWEGTCNTAGCTELFVMVHENANHSYYSHILKYDVETQ", "length": 684, "header": "tr|A0A1L1RZ57-1|A0A1L1RZ57_CHICK Isoform 1 of Kyphoscoliosis peptidase OS=Gallus gallus OX=9031 GN=KY PE=4 SV=1 CANONICAL=A0A1L1RZ57-1" }, "locus": { "chromosome": "9", "start_pos": 3358491, "end_pos": 3346821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059874.1", "url": "https://www.ensembl.org/id/ENSGALT00010059874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036634.1", "url": "https://www.ensembl.org/id/ENSGALP00010036634.1" } ] } }, { "isoform_ac": "A0A3Q2TVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVX1/entry", "sequence": { "sequence": "MENIRSFCITWTQRLCCCCCKGGEDKSTELTQVEVRAATRQDQQPSSTGLQDDGNGNGRPQPPPKRDLSGQQDPKEPHKQKQTVTSYTNEGTHVTVEIHPKGTSPQFFKKLSFGKGPRRVPSLRGQDNKAFERTEAPRPPSTKDLHVYPWDKSSLKSLAVDLQKFEKLDAYALKVNTKGSVEELVQTLLKQARTDLEKVRVIWMWICHHIEYDVVGFHNKSLRLCKPTDVLRTGKSVCEGYAGLFQQMCSVAGIQCMKLSGYSKGYGYKIGQTFQGNSDHAWNAVYLDGRWHLLDSTWGSGTVDDALTKFTFKYNEFYFLTHPALFVNNHFPDNSNWQLLKPTLTLKQFESNLQHNSDFYNLGLLAAHPQTALIQTENGTATISVECRPSTLFTFKLEGTDEHGLLTLRKQGMKLELYPQKTGRQELQIFARPSKSTEDVYTCVLEYIVECKSVDKSRCFPKDLHQPVGPSWFTEKQGFLRPSHPDPIIHTNDGRCSLTFTLGKDISILASLHADSSSLSEEMSRQHIMQIHRGNQVEFKVHLPHAGSFVLKFFTKKKSDPGSYSFIFNYLITCLNTEVKWPAFPLRYSKWAEGYELLEPLSRLLPANRNVQFKLKMQGISKVLVQAGDTYTLTLSRDGFWEGTCNTAGCTELFVMVHENANHSYYSHILKYDVETQ", "length": 677, "header": "tr|A0A3Q2TVX1-1|A0A3Q2TVX1_CHICK Computationally mapped isoform of Kyphoscoliosis peptidase OS=Gallus gallus OX=9031 GN=KY PE=4 SV=1 CANONICAL=A0A1L1RZ57-1" }, "locus": { "chromosome": "9", "start_pos": 3367305, "end_pos": 3346821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059880.1", "url": "https://www.ensembl.org/id/ENSGALT00010059880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036640.1", "url": "https://www.ensembl.org/id/ENSGALP00010036640.1" } ] } }, { "isoform_ac": "A0A8V0ZT23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT23/entry", "sequence": { "sequence": "MHHGPSREGCAAAAAREAKTNPPSSVEVRAATRQDQQPSSTGLQDDGNGNGRPQPPPKRDLSGQQDPKEPHKQKQTVTSYTNEGTHVTVEIHPKGTSPQFFKKLSFGKGPRRVPSLRGQDNKAFERTEAPRPPSTKDLHVYPWDKSSLKSLAVDLQKFEKLDAYALKVNTKGSVEELVQTLLKQARTDLEKVRVIWMWICHHIEYDVVGFHNKSLRLCKPTDVLRTGKSVCEGYAGLFQQMCSVAGIQCMKLSGYSKGYGYKIGQTFQGNSDHAWNAVYLDGRWHLLDSTWGSGTVDDALTKFTFKYNEFYFLTHPALFVNNHFPDNSNWQLLKPTLTLKQFESNLQHNSDFYNLGLLAAHPQTALIQTENGTATISVECRPSTLFTFKLEGTDEHGLLTLRKQGMKLELYPQKTGRQELQIFARPSKSTEDVYTCVLEYIVECKSVDKSRCFPKDLHQPVGPSWFTEKQGFLRPSHPDPIIHTNDGRCSLTFTLGKDISILASLHADSSSLSEEMSRQHIMQIHRGNQVEFKVHLPHAGSFVLKFFTKKKSDPGSYSFIFNYLITCLNTEVKWPAFPLRYSKWAEGYELLEPLSRLLPANRNVQFKLKMQGISKVLVQAGDTYTLTLSRDGFWEGTCNTAGCTELFVMVHENANHSYYSHILKYDVETQ", "length": 670, "header": "tr|A0A8V0ZT23-1|A0A1L1RZ57_CHICK Computationally mapped isoform of Kyphoscoliosis peptidase OS=Gallus gallus OX=9031 GN=KY PE=4 SV=1 CANONICAL=A0A1L1RZ57-1" }, "locus": { "chromosome": "9", "start_pos": 3366761, "end_pos": 3346821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059885.1", "url": "https://www.ensembl.org/id/ENSGALT00010059885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036645.1", "url": "https://www.ensembl.org/id/ENSGALP00010036645.1" } ] } }, { "isoform_ac": "A0A8V0ZY75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY75/entry", "sequence": { "sequence": "MLYHGNGKDPRKEDVQFGSSKESTGMGGSSRVCLSGLQDDGNGNGRPQPPPKRDLSGQQDPKEPHKQKQTVTSYTNEGTHVTVEIHPKGTSPQFFKKLSFGKGPRRVPSLRGQDNKAFERTEAPRPPSTKDLHVYPWDKSSLKSLAVDLQKFEKLDAYALKVNTKGSVEELVQTLLKQARTDLEKVRVIWMWICHHIEYDVVGFHNKSLRLCKPTDVLRTGKSVCEGYAGLFQQMCSVAGIQCMKLSGYSKGYGYKIGQTFQGNSDHAWNAVYLDGRWHLLDSTWGSGTVDDALTKFTFKYNEFYFLTHPALFVNNHFPDNSNWQLLKPTLTLKQFESNLQHNSDFYNLGLLAAHPQTALIQTENGTATISVECRPSTLFTFKLEGTDEHGLLTLRKQGMKLELYPQKTGRQELQIFARPSKSTEDVYTCVLEYIVECKSVDKSRCFPKDLHQPVGPSWFTEKQGFLRPSHPDPIIHTNDGRCSLTFTLGKDISILASLHADSSSLSEEMSRQHIMQIHRGNQVEFKVHLPHAGSFVLKFFTKKKSDPGSYSFIFNYLITCLNTEVKWPAFPLRYSKWAEGYELLEPLSRLLPANRNVQFKLKMQGISKVLVQAGDTYTLTLSRDGFWEGTCNTAGCTELFVMVHENANHSYYSHILKYDVETQ", "length": 664, "header": "tr|A0A8V0ZY75-1|A0A1L1RZ57_CHICK Computationally mapped isoform of Kyphoscoliosis peptidase OS=Gallus gallus OX=9031 GN=KY PE=4 SV=1 CANONICAL=A0A1L1RZ57-1" }, "locus": { "chromosome": "9", "start_pos": 3359543, "end_pos": 3346821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059876.1", "url": "https://www.ensembl.org/id/ENSGALT00010059876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036636.1", "url": "https://www.ensembl.org/id/ENSGALP00010036636.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769840", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HPJ6-1", "protein_name": "Kyphoscoliosis peptidase", "gene_name": "Ky", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELKKDSNAVAIDMLLIVHSEKRRAAQATQLDSQTDPGALLQNRGGFQGVRNGIRKWQELERNGFQGNLSEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMPQLLKKFSLAKRLQGDKNGNMRPRQPGGKDAHAYPWDRSSLKSMPLDLRHFEKLDASASQVTVKSGLDELVSDLIQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRIAGVQCVTVPGYSKGFGYQTGQSFSGEFDHAWNAVYLEGHWHLLDSTWGSGLVDTTTSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVNGKATVTIESCAPTLFMFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSEIYSSVLEYTLKCNYVDLSVRLPAELHQPVGPSWFSEQMGITKPSHPDPIIHTSDGRCSISFGVEEGISVLASLHGDDGTITEETQRRYIFQLDREKRTELKVQLPHAGKFALKIFVKKRQEQGNFIFVFNYLLCCANTKVNWPMFPESFGNWGQGNELLEPLSGVLPANRNIPFKLKLHGIAKALVKGQDTWPLTLNPEGYWEGSCNTAGCQEIYVMVLENANHNFYSYILKYKVNDQ", "length": 661 }, "evidence": [ { "id": "A0A1L1RZ57", "url": "https://omabrowser.org/oma/group/A0A1L1RZ57/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A5G2RA24-1", "protein_name": "Kyphoscoliosis peptidase", "gene_name": "KY", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELKKDSNSVSIDMLLIVHSEKRRAAQGAHSDRQTDPGAPPQRRGGLQVIGNGIRRWQKLEGSDLHGTQLTVEVHPRDAMPQLLKKFSLAKRLQGDKNGNTRPRQPGGKDAHAYPWDRSSLKSMPLDLRQFEKLDAYASQVMVKSGLDELVSDLLQEAHSDLERVRAIWIWICHHIEYDIEAAQEKDRQAFKPTTILQTQKTNCDGYAGLFERMCRIAGVQCMTVPGYSKGFGYQPGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSGLVDSATSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSIIKTVNGKATVTIESCAPTLFMFMLNGKQEHGLLSLRKNGMKLDVYPPTVGTHKLQIFAKGNSEIYSSVLEYTLKCHYADIDVRLPAELHQPVGPSWFSEQMGITKPSHPEPVIYTSDGRCSISFGVEEGISVLASLHGDDGPITEETQRRYIFQLHREKHTELKVQLPHAGKFALKIFVKKRQEPGNYIFVFNYLLCCTNTKVNWPVFPESFGNWGQDNELLEPLSGVLPANRNVPFKLKLHGVAKALVKGQDTWPLTLNREGYWEGSCSTAGCQEVYVMVLENANHNFYSYILKYKVNDTQ", "length": 641 }, "evidence": [ { "id": "A0A1L1RZ57", "url": "https://omabrowser.org/oma/group/A0A1L1RZ57/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z953-1", "protein_name": "Kyphoscoliosis peptidase", "gene_name": "Ky", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELKKDSNAVAIDMLLIVHSEKRRAAQATHLDPQADPGALLQNRGGFQGVRNGIRKWQELEENGFQGNLPEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMPQLLKKFSLAKRLQGDKNGNMRPRQPGGKDAHAYPWDRSNLKSMPLDLRHFEKLDASASQVTLKSGLNELVSDLLQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTNILRTRKTNCDGYAGLFERMCRVAGVQCVTVPGYSKGFGYKTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSGLVDTATSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETPMIRTVNGKATVTIESRAPTLFMFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSEIYSSVLEYTLKCNYVDFSVRLPTELHQPVGPSWFSEQMGIRKPSHPDPIIHTSDGRCSISFVVEEGISILASLHGDDSPITEETKRRYIFQMNREKRTELKVQLPHAGKFALKIFVKKRQEQGNFVFVFNYLLCCANTKVNWPMFPEIYGHWGQDNELLEPLSGVLPANRNIPFKLKLHGIAKALVKGQDTWPLTLNPEGYWEGSCNTAGCQEVYVMVLENANHNFYSYILKYKVNDQ", "length": 661 }, "evidence": [ { "id": "A0A1L1RZ57", "url": "https://omabrowser.org/oma/group/A0A1L1RZ57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C8H8-1", "protein_name": "Kyphoscoliosis peptidase", "gene_name": "Ky", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELKKDSNAVAIDMLLIVHSEKRRAAQATHLDPQANPGALLQNRGGFQGVRNGIRKWQELEENSFQGNLPEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMPQLLKKFSLAKRLQGDKNGNMRPRQPGGKDAHAYPWDRSSLKSMPLDLRLFEKLDASASQVTVKSGLNELVSDLLQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRVAGVQCVTVPGYSKGFGYQTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSGLVDTTTSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENSMYHKSEFYNKGMLSAHPETSMIRTVNGKATITIESRAPTLFMFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSEIYSSVLEYTLKCNYVDFSVQLPSELHQPVGPSWFSEQMGITKPSHSDPIIHTSDGRCAISFSVEEGVSVLASLHGDDGPITEETQRRYIFQLNRGKRTELKVQLPHAGKFALKIFVKKRQEQGNFIFVFNYLLCCANTKVNWPMFPESFGNWGQDNELLEPLSGVLPANRNVAFKLKLHGIAKALVKGQDTWPLTLNPEGYWEGSCNTAGCQEVYVMVLENANHNFYSYILKYKVNDQ", "length": 661 }, "evidence": [ { "id": "A0A1L1RZ57", "url": "https://omabrowser.org/oma/group/A0A1L1RZ57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBH2-4", "protein_name": "Kyphoscoliosis peptidase", "gene_name": "KY", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELKKDINAVSIDMLLIVHSEKRRAAQGTLSDQQANPSSLLQRGGGFQGVGNGVRRWQKLEGNDFHENLVEKQHPQQPQVITSYNSQGTQLTVEVHPRDAMPQLLKKFSLAKRLQGDKNGNTRPRQPGGKDAHAYPWDRSSLKSMSLDLQQFEKLDIYASQVTAKSGLDELVSDLLQEAHTDLERVRAIWIWICHHIEYDIAAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRLAGVQCMTVPGYSKGFGYQTGQSFSGEFDHAWNAVYLEGRWHLVDSTWGSGLVDTITSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVNGKATVTIESCAPTLFMFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSDIYSSVLEYTLKCNYVDMGVQLPAELHQPVGPSWFSEQMGIMKPSHPDPIIHTSDGRCSISFSVEEGINVLASLHGDDGPITEETQRRYIFQLHREKQTELKVQLPHAGKFALKIFVKKRQEPGNYIFVFNYLVCCANTKVNWPMFPESFGNWGQDNELLEPLSGVLPANRNVPFKLKLHGIAKVLVKGQDTWPLTLNHEGYWEGSCSTAGCQEVYVMVLENANHNFYSYILKYKVNAQ", "length": 661 }, "evidence": [ { "id": "A0A1L1RZ57", "url": "https://omabrowser.org/oma/group/A0A1L1RZ57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZ57", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1L1RZ57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 684, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1L1RZ57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A1L1RZ57" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A1L1RZ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZ57" }, { "id": "SM00460", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00460" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transglutaminase-like", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 305, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 669, "end_pos": 671 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZQ0-1", "uniprot_ac": "A0A1L1RZQ0", "uniprot_id": "A0A1L1RZQ0_CHICK", "mass": { "chemical_mass": 9907.0, "monoisotopic_mass": 9907.0 }, "refseq": { "ac": "XP_040521197", "name": "feather keratin 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521197" }, "gene_names": [ { "name": "LOC121110033", "type": "recommended", "evidence": [ { "id": "A0A1L1RZQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0" } ] }, { "name": "LOC121110033", "type": "synonym", "evidence": [ { "id": "XP_040521197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521197" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A1L1RZQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0/entry#names_and_taxonomy" } ] }, { "name": "feather keratin 1-like", "type": "synonym", "evidence": [ { "id": "XP_040521197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521197" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040521197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZQ0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121110033", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000049723", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049723", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "121110033", "url": "https://www.ncbi.nlm.nih.gov/gene/121110033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZQ0", "url": "https://www.orthodb.org/?gene=A0A1L1RZQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040521197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZQ0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSNLCRPCGPTPLANSCNEPCVRQCQDSQVVIQPPAVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A1L1RZQ0-1|A0A1L1RZQ0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121110033 PE=3 SV=2 CANONICAL=A0A1L1RZQ0-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0/entry", "sequence": { "sequence": "MSCSNLCRPCGPTPLANSCNEPCVRQCQDSQVVIQPPAVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A1L1RZQ0-1|A0A1L1RZQ0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121110033 PE=3 SV=2 CANONICAL=A0A1L1RZQ0-1" }, "locus": { "chromosome": "2", "start_pos": 147963808, "end_pos": 147963515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023101.1", "url": "https://www.ensembl.org/id/ENSGALT00010023101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013366.1", "url": "https://www.ensembl.org/id/ENSGALP00010013366.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZQ0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZQ0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZT1-1", "uniprot_ac": "A0A1L1RZT1", "uniprot_id": "A0A1L1RZT1_CHICK", "mass": { "chemical_mass": 47012.0, "monoisotopic_mass": 47012.0 }, "refseq": { "ac": "XP_003643535", "name": "plasmalemma vesicle-associated protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643535" }, "gene_names": [ { "name": "PLVAP", "type": "recommended", "evidence": [ { "id": "A0A1L1RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1" } ] }, { "name": "PLVAP", "type": "synonym", "evidence": [ { "id": "XP_003643535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643535" } ] } ], "protein_names": [ { "name": "Plasmalemma vesicle associated protein", "type": "synonym", "evidence": [ { "id": "A0A1L1RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1/entry#names_and_taxonomy" } ] }, { "name": "plasmalemma vesicle-associated protein", "type": "synonym", "evidence": [ { "id": "XP_003643535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643535" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643535" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZT1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLVAP", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1", "locus": {} } ], "crossref": [ { "id": "A0A1L1RZT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1RZT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000045684", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000045684", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857417", "url": "https://www.ncbi.nlm.nih.gov/gene/100857417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857417", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETNKSCD", "url": "https://omabrowser.org/oma/group/ETNKSCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZT1", "url": "https://www.orthodb.org/?gene=A0A1L1RZT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9U1", "url": "https://www.orthodb.org/?gene=A0A8V1A9U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21687:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21687:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZT1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKNSYGMAKFGLESKQAMPKQDCAFYMRYIFLFTSLIQFLIILGLVLFMVYGNAHAGTDKHVRLLDEQLQEHYHKIISLSGRNANLTRTLNATLKANQGLQGQLQKVQGQLEKCNSSQAPHGSPRLEDIRRTVLLQKTYLDNCYVTTKIINASCNAEKAQLQEQLNTAMQQKKELGQNSSKAAAALGKARQEQERCQQELKATGVLCDTTKAQLEHLKGERDTLRSNVLYNLRTMSISNKNFGCSQVEEQLRLLMHRIDELFSRQQKHESDYVGKSICDLTLQQCHLNCSHEKLELGRRLQEVQQQLRGGQEEQRKLLAEKERLSKELGEKSKAAAQANYFSEQLNLCMSTKVGTYYTAPQVPGSAVGSVRPVPFPSSYADALQNQDKIGMEDIQKMVQNMMEQYTAMMRNLSG", "length": 415, "header": "tr|A0A1L1RZT1-1|A0A1L1RZT1_CHICK Isoform 1 of Plasmalemma vesicle associated protein OS=Gallus gallus OX=9031 GN=PLVAP PE=1 SV=1 CANONICAL=A0A1L1RZT1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZT1/entry", "sequence": { "sequence": "MEKNSYGMAKFGLESKQAMPKQDCAFYMRYIFLFTSLIQFLIILGLVLFMVYGNAHAGTDKHVRLLDEQLQEHYHKIISLSGRNANLTRTLNATLKANQGLQGQLQKVQGQLEKCNSSQAPHGSPRLEDIRRTVLLQKTYLDNCYVTTKIINASCNAEKAQLQEQLNTAMQQKKELGQNSSKAAAALGKARQEQERCQQELKATGVLCDTTKAQLEHLKGERDTLRSNVLYNLRTMSISNKNFGCSQVEEQLRLLMHRIDELFSRQQKHESDYVGKSICDLTLQQCHLNCSHEKLELGRRLQEVQQQLRGGQEEQRKLLAEKERLSKELGEKSKAAAQANYFSEQLNLCMSTKVGTYYTAPQVPGSAVGSVRPVPFPSSYADALQNQDKIGMEDIQKMVQNMMEQYTAMMRNLSG", "length": 415, "header": "tr|A0A1L1RZT1-1|A0A1L1RZT1_CHICK Isoform 1 of Plasmalemma vesicle associated protein OS=Gallus gallus OX=9031 GN=PLVAP PE=1 SV=1 CANONICAL=A0A1L1RZT1-1" }, "locus": { "chromosome": "28", "start_pos": 3876571, "end_pos": 3874396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069287.1", "url": "https://www.ensembl.org/id/ENSGALT00010069287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042729.1", "url": "https://www.ensembl.org/id/ENSGALP00010042729.1" } ] } }, { "isoform_ac": "A0A8V1A9U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9U1/entry", "sequence": { "sequence": "MEKNSYGMAKFGLESKQAMPKQDCAFYMRYIFLFTSLIQFLIILGLVLFMVYGNAHAGTDKHVRLLDEQLQEHYHKIISLSGRNANLTRTLNATLKANQGLQGQLQKVQGQLEKCNSSQAPHGSPRLEDIRRTVLLQKTYLDNCYVTTKIINASCNAEKAQLQEQLNTAMQQKKELGQNSSKAAAALGKARQEQERCQQELKATGVLCDTTKAQLEHLKGERDTLRSNVLYNLRTMSISNKNFGCSQVEEQLRLLMHRIDELFSRQQKHESDYVGKSICDLTLQQCHLNCSHEKLELGRRLQEEQRKLLAEKERLSKELGEKSKAAAQANYFSEQLNLCMSTKVGTYYTAPQVPGSAVGSVRPVPFPSSYADALQNQDKIGMEDIQKMVQNMMEQYTAMMRNLSG", "length": 405, "header": "tr|A0A8V1A9U1-1|A0A1L1RZT1_CHICK Computationally mapped isoform of Plasmalemma vesicle associated protein OS=Gallus gallus OX=9031 GN=PLVAP PE=1 SV=1 CANONICAL=A0A1L1RZT1-1" }, "locus": { "chromosome": "28", "start_pos": 3876571, "end_pos": 3874396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069290.1", "url": "https://www.ensembl.org/id/ENSGALT00010069290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042732.1", "url": "https://www.ensembl.org/id/ENSGALP00010042732.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857417", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857417", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AU22-1", "protein_name": "Plasmalemma vesicle associated protein", "gene_name": "PLVAP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLAMEHGGPYSRAGGSPRGCWYYMRYFFLFLSLIQFLIILGLVLFMVYGNVHVSTESNLQATERRADGLYGQVMGLTASQANLSKELNLTTRARDAIMQMLLSARREQDRINSSFRQCQADRAIHLNNQVYMAAIILSEKQCQEQLKETNKSCNDLNLMLNQKVKTLEVELSKEKLVCMKDKESLVLSKRVVEEQLVECSKAREQQRQERQLAEERLQKVQTLCLLLDKDKIETELRSLWRDSIISRSLDSLGYNMYHPLGSELASIRRTCDHMPTLMSAKVEEMARSLRAGIERVTRENSDLQRQKLEVQQGLQATQEAKEKVEKEAQAREAKLQAECTRQTQLALEEKAALRKEKDNLAKELEEKKREIEQLKMELAISKSALDTCIKAKSQPIPGPRPVGPVPNPPPIDSATLEEFKRRILESQRPPASNAIASASG", "length": 441 }, "evidence": [ { "id": "A0A1L1RZT1", "url": "https://omabrowser.org/oma/group/A0A1L1RZT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1Q8W5-1", "protein_name": "Plasmalemma vesicle associated protein b", "gene_name": "plvapb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYKNSYSQATFGLEAKKIHKAKKGKSCGYYMRIVFFFSSLIQSLIIASLVLFLVYGQPEKTAEEKRLEDLQQAYDTLSKDHTKLRKEKADLATALKTKSGEKDAADKEITKLKTDLNISIAGSKNWQRLNSQCEANAKLKLSSTRNTPLMCPPANPNQSGEVKTLNTLLDQQKALYGILKSNFSQTVEYLKSDLDHAVKDKNEHHSQVIKLRQENKDLKSQLDVYTKKCKEDFADSLQGIQTVTTAFLSKIDNFFTNSVTFHLTCPKQEEQMDRIRSNCSSLSRQVEDKFQSYLNNVGAKVSNIQKQSSWLEIQNEKLTSELDKCKTEAEKEASDSSKKLQDAQTTCDKQLEQLLKEQTRLRNAKDLVDTELSVKEATIISLQKGCTPQAKPSGFQPLGSAGQYPSTSG", "length": 409 }, "evidence": [ { "id": "A0A1L1RZT1", "url": "https://omabrowser.org/oma/group/A0A1L1RZT1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91VC4-1", "protein_name": "Plasmalemma vesicle-associated protein", "gene_name": "Plvap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSMDRSPYARTGDQQRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESSLRATEIRADSLYSQVVGLSASQANLSKQLNISLLVKETVMQQLLTTRREMERINASFRQCQGDLITYINYNRFIAAIILSEKQCQEQLKEVNKTCEALLFKLGEKVKTLEMEVAKEKAVCSKDKESLLAGKRQTEEQLEACGKARERQQQEQQVTEENLRKVQSLCIPLDQEKFQADVLSAWRDSLIYRTLETLPYHYQLMPEYASLRRTCESLPGIMTTKIEELARGLRAGIERVTRENAELRRQKLELERAAQAAQEARARAGTEAQARETQLRAECARQTQLALEEKAALRAQRDNLERELEARKRELEQLRTEVDVRISALDTCVKAKSLPAVPPRVSGPPPNPPPIDPASLEEFKKRILESQRLPVVNPAAQPSG", "length": 438 }, "evidence": [ { "id": "A0A1L1RZT1", "url": "https://omabrowser.org/oma/group/A0A1L1RZT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BX97-1", "protein_name": "Plasmalemma vesicle-associated protein", "gene_name": "PLVAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLAMEHGGSYARAGGSSRGCWYYLRYFFLFVSLIQFLIILGLVLFMVYGNVHVSTESNLQATERRAEGLYSQLLGLTASQSNLTKELNFTTRAKDAIMQMWLNARRDLDRINASFRQCQGDRVIYTNNQRYMAAIILSEKQCRDQFKDMNKSCDALLFMLNQKVKTLEVEIAKEKTICTKDKESVLLNKRVAEEQLVECVKTRELQHQERQLAKEQLQKVQALCLPLDKDKFEMDLRNLWRDSIIPRSLDNLGYNLYHPLGSELASIRRACDHMPSLMSSKVEELARSLRADIERVARENSDLQRQKLEAQQGLRASQEAKQKVEKEAQAREAKLQAECSRQTQLALEEKAVLRKERDNLAKELEEKKREAEQLRMELAIRNSALDTCIKTKSQPMMPVSRPMGPVPNPQPIDPASLEEFKRKILESQRPPAGIPVAPSSG", "length": 442 }, "evidence": [ { "id": "A0A1L1RZT1", "url": "https://omabrowser.org/oma/group/A0A1L1RZT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV78-1", "protein_name": "Plasmalemma vesicle-associated protein", "gene_name": "Plvap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A1L1RZU1-1", "uniprot_ac": "A0A1L1RZU1", "uniprot_id": "A0A1L1RZU1_CHICK", "mass": { "chemical_mass": 11700.0, "monoisotopic_mass": 11700.0 }, "refseq": {}, "gene_names": [ { "name": "POLR1D", "type": "recommended", "evidence": [ { "id": "A0A1L1RZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZU1" } ] } ], "protein_names": [ { "name": "RNA polymerase I and III subunit D", "type": "synonym", "evidence": [ { "id": "A0A1L1RZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZU1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1RZU1", "url": 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This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon. 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012855" } ] } ], "protein_names": [ { "name": "NECAP endocytosis associated 2", "type": "synonym", "evidence": [ { "id": "A0A1L1S0X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6/entry#names_and_taxonomy" } ] }, { "name": "adaptin ear-binding coat-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001012855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012855" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01001263.1, HAEK01010753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Sep 23, 2021 this sequence version replaced NP_001012855.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012855" } ] }, { "annotation": "Involved in endocytosis.", "evidence": [ { "database": "UniProtKB", "id": "F1NN78", "url": "https://www.uniprot.org/uniprotkb/F1NN78#function" }, { "database": "UniProtKB", "id": "ARBA00002550", "url": "https://www.uniprot.org/uniprotkb/ARBA00002550#function" }, { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NECAP2", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6", "locus": { "chromosome": "21", "start_pos": 4388832, "end_pos": 4381932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020338", "url": "https://www.ensembl.org/id/ENSGALG00010020338" } ] } } ], "crossref": [ { "id": "A0A1L1S0X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A1L1S0X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003745", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003745", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419464", "url": "https://www.ncbi.nlm.nih.gov/gene/419464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419464", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEGHRAQ", "url": "https://omabrowser.org/oma/group/NEGHRAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1S0X6", "url": "https://www.orthodb.org/?gene=A0A1L1S0X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDW5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKC4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NN78", "url": "https://www.orthodb.org/?gene=F1NN78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12847", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12847", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12847:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12847:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07933", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07933", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1S0X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NN78", "url": "https://www.uniprot.org/uniprotkb/F1NN78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NN78-1", "url": "https://www.uniprot.org/uniprotkb/F1NN78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDYEAVLCVKPAVHVYRVPPRASNRGYRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPGIAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNELAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGGLSLLPPPPGGKSSMPTLPSGEQLPSSLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGSDSNQTQANAGWVQF", "length": 266, "header": "tr|A0A1L1S0X6-1|A0A1L1S0X6_CHICK Isoform 1 of NECAP endocytosis associated 2 OS=Gallus gallus OX=9031 GN=NECAP2 PE=1 SV=1 CANONICAL=A0A1L1S0X6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1S0X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6/entry", "sequence": { "sequence": "MEEDYEAVLCVKPAVHVYRVPPRASNRGYRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPGIAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNELAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGGLSLLPPPPGGKSSMPTLPSGEQLPSSLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGSDSNQTQANAGWVQF", "length": 266, "header": "tr|A0A1L1S0X6-1|A0A1L1S0X6_CHICK Isoform 1 of NECAP endocytosis associated 2 OS=Gallus gallus OX=9031 GN=NECAP2 PE=1 SV=1 CANONICAL=A0A1L1S0X6-1" }, "locus": { "chromosome": "21", "start_pos": 4386463, "end_pos": 4381995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049133.1", "url": "https://www.ensembl.org/id/ENSGALT00010049133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029047.1", "url": "https://www.ensembl.org/id/ENSGALP00010029047.1" } ] } }, { "isoform_ac": "A0A8V0ZDW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW5/entry", "sequence": { "sequence": "MEEDYEAVLCVKPAVHVYRVPPRASNRGYRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPGIAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNELAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGGLSLLPPPPGGKSSMPTLPSGEQLPSSLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGVQTFFFSLFLSPGQIQTRRRQMQAGCSSEPAPRRHWRKIVLISAGPKQQWEVLLLPKDTSLVTYGGTVLP", "length": 321, "header": "tr|A0A8V0ZDW5-1|A0A8V0ZDW5_CHICK Computationally mapped isoform of NECAP endocytosis associated 2 OS=Gallus gallus OX=9031 GN=NECAP2 PE=1 SV=1 CANONICAL=A0A1L1S0X6-1" }, "locus": { "chromosome": "21", "start_pos": 4386590, "end_pos": 4381995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049126.1", "url": "https://www.ensembl.org/id/ENSGALT00010049126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029043.1", "url": "https://www.ensembl.org/id/ENSGALP00010029043.1" } ] } }, { "isoform_ac": "A0A8V0ZKC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC4/entry", "sequence": { "sequence": "MEEDYEAVLCVKPAVHVYRVPPRASNRGYRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPGIAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNELAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGGLSLLPPPPGGKSSMPTLPSGEQLPSSLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGAEAKP", "length": 256, "header": "tr|A0A8V0ZKC4-1|A0A8V0ZKC4_CHICK Computationally mapped isoform of NECAP endocytosis associated 2 OS=Gallus gallus OX=9031 GN=NECAP2 PE=1 SV=1 CANONICAL=A0A1L1S0X6-1" }, "locus": { "chromosome": "21", "start_pos": 4388779, "end_pos": 4381995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049137.1", "url": "https://www.ensembl.org/id/ENSGALT00010049137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029050.1", "url": "https://www.ensembl.org/id/ENSGALP00010029050.1" } ] } }, { "isoform_ac": "F1NN78-1", "url": "https://www.uniprot.org/uniprotkb/F1NN78/entry", "sequence": { "sequence": "MVQCRTTGLFPSASASGQQIWGVMRGLVMRLPVCSKPRAAEWQLDQPAWSGRLRITAKGKTAFIKLEDKTSGELFAQAPVEQFPGIAVESVTDSSRYFVLRIEDGNGRRAFIGVGFVDRGDAFDFNVALQDHFKWVRQQNELAKQSENPDQAPKLDLGFKEGQTIKLNIANMKKKEGATGNTRPRPAGPGGLSLLPPPPGGKSSMPTLPSGEQLPSSLSTPTRLPGTPITDSLLSWPQPTAAPSAPTTDVWGDFTKASGSDSNQTQANAGWVQF", "length": 274, "header": "tr|F1NN78-1|A0A1L1S0X6_CHICK Computationally mapped isoform of NECAP endocytosis associated 2 OS=Gallus gallus OX=9031 GN=NECAP2 PE=1 SV=3 CANONICAL=A0A1L1S0X6-1" }, "locus": { "chromosome": "21", "start_pos": 4386463, "end_pos": 4382654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049121.1", "url": "https://www.ensembl.org/id/ENSGALT00010049121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029038.1", "url": "https://www.ensembl.org/id/ENSGALP00010029038.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419464", "resource": "KEGG Pathway" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SUS2-1", "protein_name": "NECAP endocytosis associated 2", "gene_name": "NECAP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEGGYESVLCVKPEVHVYRIPPRATNRGYRASEWQLDQPSWSGRLRITAKGQVAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDQGPKLDLSFKEGQTIKLNIANMKKKEGAAGTPRARPASTGGLSLLPPPPGGRTSTLTAHPGEHLSVGGSVIQPAVVPSSGGATVSWPQPKPATAATADIWGDFTKSTGSTSSQPQPGTGWVQF", "length": 266 }, "evidence": [ { "id": "A0A1L1S0X6", "url": "https://omabrowser.org/oma/group/A0A1L1S0X6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q681Q7-1", "protein_name": "Uncharacterized protein At1g03900", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSFEEEEEEETFEHTLLVVREVSVYKIPPRTTSGGYKCGEWLQSDKIWSGRLRVVSCKDRCEIRLEDSNSGDLFAACFVDPGRRENSVEPSLDSSRYFVLRIDDGRGKYAFIGLGFAERNEAFDFNVALSDHEKYVRREKEKETGETSESDNHIDIHPAVNHRLKEGETIRINVKPKPTTNGTGMLSAALSGTGKPKPLALAPPPKAAGVTRSPLPPPPNDPVASRIASDGCKESRRNEPLSDLSQLKKNLPSTAGSGSSKSTGAASGWAAF", "length": 272 }, "evidence": [ { "id": "A0A1L1S0X6", "url": "https://omabrowser.org/oma/group/A0A1L1S0X6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D1J1-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "Necap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEESEYESVLCVKPEVHVYRIPPRATNRGYRASEWQLDQPSWSGRLRITAKGKVAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGLGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDEGPKLDLGFKDGQTIKINIANMRKKEGAAGTPRARPTSAGGLSLLPPPPGGKSSTVIPPSGEQLSVGGSLVQPAVVSGSGGATELWPQSKPAAAATADIWGDFTKSTGSPSSQSQPGTGWVQF", "length": 266 }, "evidence": [ { "id": "A0A1L1S0X6", "url": "https://omabrowser.org/oma/group/A0A1L1S0X6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGSTSSQTQPGTGWVQF", "length": 263 }, "evidence": [ { "id": "A0A1L1S0X6", "url": "https://omabrowser.org/oma/group/A0A1L1S0X6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXB0-1", "protein_name": "NECAP-like protein CG9132", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEYESVLIVKPEVFIYKIPPRASNRGYRAGDWNLKEPTWTGRMRLVAKGTAVVLKLEDKTSGALFANCPIDTYPGVAIEAVSDSSRYFVIRVQDDNGRSAFLGLGFGDRSDSFDLNVALQDHFKWVKNQEQIEKEKTEPKQELDLGFKEGETIKINMRITKKDGSEGSSRTGKNKGSSGVLPPPPGGLGKIAPPPAAAAANTTVRQSPGVSPAHRPAAGGSEWTDYASAGGNQGQQNSANANWVQF", "length": 246 }, "evidence": [ { "id": "A0A1L1S0X6", "url": "https://omabrowser.org/oma/group/A0A1L1S0X6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "pmid": "" }, { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "A0A1L1S0X6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1S0X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032780", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032780", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TRU5", "url": "https://www.orthodb.org/?gene=A0A3Q2TRU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVY7", "url": "https://www.orthodb.org/?gene=A0A8V0XVY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44523", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44523", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44523:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44523:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TRU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TRU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"MRRAKMAAAGGLGSVRGLWAPLLVLALARVAVALTEQYPTLSLLKQELNQQRQGLTGGCASAGEWTEQYSAECDSSFLHFQESDCDLRSSSSCESVLSLNTEKILSQAKSLAEQKRFPFATDNDNTNEELAIAYVLIGNGLYDEAIRQFSTMLQEEPELVSAIYGRGIAYGKKGLHDVKNAELALFELSRVISLEPDHPEVFEQRAEILSPLGRISEALSDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQHSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKADFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLKGMMLYHHGSLDEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDIDLPGNFKDHWAKNLPFLIENYEEQPGLQPHIKDVLFQNFESYRTDVQELICVADHLGSMMQYETPGFLPNKRIHRAMGLATLEVMQAVQRTWANSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLMEVREALEKVHKVEDLLPIMKFNSKTRDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKILVLSAELGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIMGALMASGKEVSGKIPKGKLVDFEAMTAPGSEAFSKIARSWMNLKSISPSYKSLPSVSETFPTLRTMIEGIQLFRGQNEEQ", "length": 840, "header": "tr|A0A3Q2TRU5-1|A0A3Q2TRU5_CHICK Isoform 1 of Tetratricopeptide repeat domain 13 OS=Gallus gallus OX=9031 GN=TTC13 PE=4 SV=1 CANONICAL=A0A3Q2TRU5-1" }, "locus": { "chromosome": "3", "start_pos": 40258318, "end_pos": 40222207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018584.1", "url": "https://www.ensembl.org/id/ENSGALT00010018584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010170.1", "url": "https://www.ensembl.org/id/ENSGALP00010010170.1" } ] } }, { "isoform_ac": "A0A8V0XVY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVY7/entry", "sequence": { "sequence": "MRRAKMAAAGGLGSVRGLWAPLLVLALARVAVALTEQYPTLSLLKQELNQQRQGLTGGCASAGEWTEQYSAECDSSFLHFQESDCDLRSSSSCESVLSLNTEKILSQAKSLAEQKRFPFATDNDNTNEELAIAYVLIGNGLYDEAIRQFSTMLQVAT", "length": 157, "header": "tr|A0A8V0XVY7-1|A0A3Q2TRU5_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 13 OS=Gallus gallus OX=9031 GN=TTC13 PE=4 SV=1 CANONICAL=A0A3Q2TRU5-1" }, "locus": { "chromosome": "3", "start_pos": 40258318, "end_pos": 40251703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018580.1", "url": "https://www.ensembl.org/id/ENSGALT00010018580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010167.1", "url": "https://www.ensembl.org/id/ENSGALP00010010167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TRU5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 840, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TRU5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TRU5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TRW9-1", "uniprot_ac": "A0A3Q2TRW9", "uniprot_id": "A0A3Q2TRW9_CHICK", "mass": { "chemical_mass": 28636.0, "monoisotopic_mass": 28636.0 }, "refseq": { "ac": "XP_015150906", "name": "uncharacterized protein LOC418355 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150906" }, "gene_names": [ { "name": "LOC418355", "type": "recommended", "evidence": [ { "id": "A0A3Q2TRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9" } ] }, { "name": "LOC418355", "type": "synonym", "evidence": [ { "id": "XP_015150906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150906" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2TRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC418355 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015150906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150906" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150906" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC418355", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TRW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TRW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000046548", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000046548", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00099", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00099", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418355", "url": "https://www.ncbi.nlm.nih.gov/gene/418355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418355", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TRW9", "url": "https://www.orthodb.org/?gene=A0A3Q2TRW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13869:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13869:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGPVAITYTYFFAHTTRAAFLPTLLTRSYISAAMSQHIGKPYGSAVSLFLFFLLMDVGVSDGNTSKENATLSHRRTQAPLLTTPEPWQVFLTQTPAKEKAKEGETVVLNCHFNSPRHPSLTGLTVGWYKEDEKGKTDLLENNKTMLPNNSRVFLSGDLSQAVVSLVILNVTTSDHGIYFCKITFPDGKVMTGDGTKLRIRRALGLFGIEESIGTIIGVVAAGIGGLGILIIILTPQLRRCILCMKQGSHQVLKNLIQPAES", "length": 262, "header": "tr|A0A3Q2TRW9-1|A0A3Q2TRW9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC418355 PE=4 SV=1 CANONICAL=A0A3Q2TRW9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9/entry", "sequence": { "sequence": "MRGPVAITYTYFFAHTTRAAFLPTLLTRSYISAAMSQHIGKPYGSAVSLFLFFLLMDVGVSDGNTSKENATLSHRRTQAPLLTTPEPWQVFLTQTPAKEKAKEGETVVLNCHFNSPRHPSLTGLTVGWYKEDEKGKTDLLENNKTMLPNNSRVFLSGDLSQAVVSLVILNVTTSDHGIYFCKITFPDGKVMTGDGTKLRIRRALGLFGIEESIGTIIGVVAAGIGGLGILIIILTPQLRRCILCMKQGSHQVLKNLIQPAES", "length": 262, "header": "tr|A0A3Q2TRW9-1|A0A3Q2TRW9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC418355 PE=4 SV=1 CANONICAL=A0A3Q2TRW9-1" }, "locus": { "chromosome": "1", "start_pos": 83143593, "end_pos": 83135611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015837.1", "url": "https://www.ensembl.org/id/ENSGALT00010015837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009166.1", "url": "https://www.ensembl.org/id/ENSGALP00010009166.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418355", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TRW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 262, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TRW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TRW9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TS11-1", "uniprot_ac": "A0A3Q2TS11", "uniprot_id": "A0A3Q2TS11_CHICK", "mass": { "chemical_mass": 40975.0, "monoisotopic_mass": 40975.0 }, "refseq": { "ac": "NP_001376433", "name": "xyloside xylosyltransferase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376433" }, "gene_names": [ { "name": "XXYLT1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ] }, { "name": "XXYLT1", "type": "synonym", "evidence": [ { "id": "NP_001376433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376433" } ] } ], "protein_names": [ { "name": "Xyloside xylosyltransferase 1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.62", "type": "synonym", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11/entry#names_and_taxonomy" } ] }, { "name": "UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase", "type": "synonym", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11/entry#names_and_taxonomy" } ] }, { "name": "xyloside xylosyltransferase 1", "type": "synonym", "evidence": [ { "id": "NP_001376433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376433" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01041372.1, SRR12888514.42299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000240.1. On Dec 29, 2020 this sequence version replaced XP_015147085.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376433" } ] }, { "annotation": "Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11#function" }, { "database": "UniProtKB", "id": "ARBA00059430", "url": "https://www.uniprot.org/uniprotkb/ARBA00059430#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XXYLT1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11", "locus": { "chromosome": "9", "start_pos": 12474224, "end_pos": 12437589, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017522", "url": "https://www.ensembl.org/id/ENSGALG00010017522" } ] } } ], "crossref": [ { "id": "A0A3Q2TS11", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TS11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054428", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424896", "url": "https://www.ncbi.nlm.nih.gov/gene/424896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424896", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVWCIFT", "url": "https://omabrowser.org/oma/group/NVWCIFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TS11", "url": "https://www.orthodb.org/?gene=A0A3Q2TS11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46612:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46612:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22820", "url": "https://www.rhea-db.org/rhea/22820", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWARSQPCALALAAALAVCAFYYLGGGGETFSSATRRLRATRAAAPPATPPGPARRERTAAGGEAGRALHLLMMFTKAERSPALRGKGQAALRSLLRHGRLRRGDALHLHLVTDGASRDIGEGLLRDALRGAAFRHQVIIHDVSELTEKLFPIVEAMQKHFSAGSGTYYSDSIFFLSVAMHRIMPKEITQIIQVDLDLKYKANIRDLFEEFDNFQEGAVIGIAREMQPVYRHTFWQYRRENPQTRVGEPPPDGLPGFNSGVLLLNLEAMRRSKLYNQLLEPGMVQKLTEKYHFKGHLGDQDFFTMVGMEHPELFHVLDCTWNRQLCTWWKDHGYSDVFDQYFRCEGEVKIYHGNCNTPIPED", "length": 363, "header": "tr|A0A3Q2TS11-1|A0A3Q2TS11_CHICK Isoform 1 of Xyloside xylosyltransferase 1 OS=Gallus gallus OX=9031 GN=XXYLT1 PE=3 SV=1 CANONICAL=A0A3Q2TS11-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TS11-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11/entry", "sequence": { "sequence": "MGWARSQPCALALAAALAVCAFYYLGGGGETFSSATRRLRATRAAAPPATPPGPARRERTAAGGEAGRALHLLMMFTKAERSPALRGKGQAALRSLLRHGRLRRGDALHLHLVTDGASRDIGEGLLRDALRGAAFRHQVIIHDVSELTEKLFPIVEAMQKHFSAGSGTYYSDSIFFLSVAMHRIMPKEITQIIQVDLDLKYKANIRDLFEEFDNFQEGAVIGIAREMQPVYRHTFWQYRRENPQTRVGEPPPDGLPGFNSGVLLLNLEAMRRSKLYNQLLEPGMVQKLTEKYHFKGHLGDQDFFTMVGMEHPELFHVLDCTWNRQLCTWWKDHGYSDVFDQYFRCEGEVKIYHGNCNTPIPED", "length": 363, "header": "tr|A0A3Q2TS11-1|A0A3Q2TS11_CHICK Isoform 1 of Xyloside xylosyltransferase 1 OS=Gallus gallus OX=9031 GN=XXYLT1 PE=3 SV=1 CANONICAL=A0A3Q2TS11-1" }, "locus": { "chromosome": "9", "start_pos": 12473460, "end_pos": 12437624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042356.1", "url": "https://www.ensembl.org/id/ENSGALT00010042356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024846.1", "url": "https://www.ensembl.org/id/ENSGALP00010024846.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424896", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424896", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZM39-1", "protein_name": "Xyloside xylosyltransferase 1", "gene_name": "XXYLT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLLRGVPPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAVPSPPVLEVARGSVAPALGAKAKSLESGGAGPVDYHLLMMFTKAEHNAALQAKARIALRSLLRLAKFEANEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVVFHDVGVLTDKLFPVVEAMQKHFSAGSGTYYSDSIFFLSVAMHQIMPKEILRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGGPPPDGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLAAKYRFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFDAYFRCEGHVKIYHGNCNTPIPEA", "length": 393 }, "evidence": [ { "id": "A0A3Q2TS11", "url": "https://omabrowser.org/oma/group/A0A3Q2TS11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADL7-1", "protein_name": "Xyloside xylosyltransferase 1", "gene_name": "Xxylt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPFRCPRSRLAPGSAVPPPLWPPPAAGLRALECCFEWARLLGRRLRRMDLLRGGAACARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAAAPTPPVPELARGSAAPASGAKAKNLEGGLAVPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEPHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEILRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYGHLLEPAWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFPAYFHCEGHVKIYHGNCNTPIPED", "length": 441 }, "evidence": [ { "id": "A0A3Q2TS11", "url": "https://omabrowser.org/oma/group/A0A3Q2TS11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F9V4-1", "protein_name": "Xyloside xylosyltransferase 1 isoform X1", "gene_name": "xxylt1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVLRVLWGIMGRISMFRSYQIVLLLAAALAVVAFYYFGSEKQNFSSTTKRIKETQASHNSNRDDADLSIDIQPGHLESRPGAGAELEGKPKRFHALMMFTKVDKSLSLQQKFQTAMRSMVKHGRFLEDEILVLHYVSDLGSQEFGEKMLPELLLDASFQYEVVFHNVDTLTEKLFPIVEAMQKHFSAGSGAYYSDAIFFLSVAMHRIMPAELKRIVQLDLDLKFRSNIRDLFQEFNHFPSDAVIGIAREMQPVYRHTFWQYRKENPKSRVGDPPPDGLPGFNSGVMLLNLDSMRRSTVYNQLLEPERVARLADKYHFRGHLGDQDFFTMIGMEHTELFYPLTCGWNRQLCTWWRDHGYGDVFQLYYHCDGPVHIHHGNCNTPIPDD", "length": 387 }, "evidence": [ { "id": "A0A3Q2TS11", "url": "https://omabrowser.org/oma/group/A0A3Q2TS11/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U4G3-1", "protein_name": "Xyloside xylosyltransferase 1", "gene_name": "Xxylt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLRGGAACARAMARLGALRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAAAPTPPAPELARGSAAPASGAKAKSLEGGVVVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPED", "length": 392 }, "evidence": [ { "id": "A0A3Q2TS11", "url": "https://omabrowser.org/oma/group/A0A3Q2TS11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBI6-1", "protein_name": "Xyloside xylosyltransferase 1", "gene_name": "XXYLT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPPEGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED", "length": 393 }, "evidence": [ { "id": "A0A3Q2TS11", "url": "https://omabrowser.org/oma/group/A0A3Q2TS11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" }, { "name": "xylosyl alpha-1,3-xylosyltransferase activity", "id": "GO:0140560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140560", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via glucose", "id": "GO:0180059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180059", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TS11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22820", "name": "", "equation": "3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2TS11-1" ], "evidence": [ { "id": "22820", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22820" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2TS11", "gene_name": "XXYLT1", "activity": [ { "ec_number": "2.4.2.62", "activity": "3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ] }, { "ec_number": "2.4.2.62", "activity": "", "evidence": [ { "id": "A0A3Q2TS11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TS11" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TS11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 363, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TS11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TS11" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.2.62", "ec_name": "3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "2.4.2.62", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.62" }, { "id": "2.4.2.62", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.2.62" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TSE5-1", "uniprot_ac": "A0A3Q2TSE5", "uniprot_id": "A0A3Q2TSE5_CHICK", "mass": { "chemical_mass": 7170.0, "monoisotopic_mass": 7170.0 }, "refseq": { "ac": "XP_015136174", "name": "small EDRK-rich factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136174" }, "gene_names": [ { "name": "LOC107052389", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5" } ] }, { "name": "LOC107052389", "type": "synonym", "evidence": [ { "id": "XP_015136174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136174" } ] } ], "protein_names": [ { "name": "Small EDRK-rich factor 1B", "type": "synonym", "evidence": [ { "id": "A0A3Q2TSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5/entry#names_and_taxonomy" } ] }, { "name": "small EDRK-rich factor 1", "type": "synonym", "evidence": [ { "id": "XP_015136174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136174" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015136174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136174" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSE5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107052389", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TSE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000051598", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000051598", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107052389", "url": "https://www.ncbi.nlm.nih.gov/gene/107052389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052389", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052389", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRDADIM", "url": "https://omabrowser.org/oma/group/NRDADIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSE5", "url": "https://www.orthodb.org/?gene=A0A3Q2TSE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y219", "url": "https://www.orthodb.org/?gene=A0A8V0Y219", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13596:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13596:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04419", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04419", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015136174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSE5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y219", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y219-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y219-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRGNQRELARQKNLKKTQETLKGKRKEDSLSASQRKQRDSEIMQQKQKAANERKSLQAGAK", "length": 62, "header": "tr|A0A3Q2TSE5-1|A0A3Q2TSE5_CHICK Isoform 1 of Small EDRK-rich factor 1B OS=Gallus gallus OX=9031 GN=LOC107052389 PE=3 SV=1 CANONICAL=A0A3Q2TSE5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5/entry", "sequence": { "sequence": "MTRGNQRELARQKNLKKTQETLKGKRKEDSLSASQRKQRDSEIMQQKQKAANERKSLQAGAK", "length": 62, "header": "tr|A0A3Q2TSE5-1|A0A3Q2TSE5_CHICK Isoform 1 of Small EDRK-rich factor 1B OS=Gallus gallus OX=9031 GN=LOC107052389 PE=3 SV=1 CANONICAL=A0A3Q2TSE5-1" }, "locus": { "chromosome": "Z", "start_pos": 73578353, "end_pos": 73572719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022553.1", "url": "https://www.ensembl.org/id/ENSGALT00010022553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012995.1", "url": "https://www.ensembl.org/id/ENSGALP00010012995.1" } ] } }, { "isoform_ac": "A0A8V0Y219-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y219/entry", "sequence": { "sequence": "MTRGNQRELARQKNLKKTQETLKGKRKEDSLSASQRKQRDSEIMQQKQKIIHKMACH", "length": 57, "header": "tr|A0A8V0Y219-1|A0A3Q2TSE5_CHICK Computationally mapped isoform of Small EDRK-rich factor 1B OS=Gallus gallus OX=9031 GN=LOC107052389 PE=3 SV=1 CANONICAL=A0A3Q2TSE5-1" }, "locus": { "chromosome": "Z", "start_pos": 73578353, "end_pos": 73572638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022558.1", "url": "https://www.ensembl.org/id/ENSGALT00010022558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013000.1", "url": "https://www.ensembl.org/id/ENSGALP00010013000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107052389", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052389", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O75920-1", "protein_name": "Small EDRK-rich factor 1", "gene_name": "SERF1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGNQRELARQKNMKKTQEISKGKRKEDSLTASQRKQSSGGQKSESKMSAGPHLPLKAPRENPCFPLPAAGGSRYYLAYGSITPISAFVFVVFFSVFFPSFYEDFCCWI", "length": 110 }, "evidence": [ { "id": "A0A3Q2TSE5", "url": "https://omabrowser.org/oma/group/A0A3Q2TSE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3E7B7-1", "protein_name": "SERF-like protein YDL085C-A", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARGNQRDLARQKNLKKQKDMAKNQKKSGDPKKRMESDAEILRQKQAAADARREAEKLEKLKAEKTRR", "length": 68 }, "evidence": [ { "id": "A0A3Q2TSE5", "url": "https://omabrowser.org/oma/group/A0A3Q2TSE5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9VEW2-1", "protein_name": "Putative SERF-like protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRGNQRDLARQKNQKKQADLTKGKRTDNLTVEQRKARDAELMREKQKKKEEAAAAGTSK", "length": 60 }, "evidence": [ { "id": "A0A3Q2TSE5", "url": "https://omabrowser.org/oma/group/A0A3Q2TSE5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TSE5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 62, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TSE5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSE5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSE5" }, { "id": "PF04419", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04419" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small EDRK-rich factor-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 37, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TSH3-1", "uniprot_ac": "A0A3Q2TSH3", "uniprot_id": "A0A3Q2TSH3_CHICK", "mass": { "chemical_mass": 270401.0, "monoisotopic_mass": 270401.0 }, "refseq": {}, "gene_names": [ { "name": "PCNX1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3" } ] } ], "protein_names": [ { "name": "Pecanex-like protein", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCNX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3", "locus": { "chromosome": "5", "start_pos": 26719981, "end_pos": 26802537, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021293", "url": "https://www.ensembl.org/id/ENSGALG00010021293" } ] } } ], "crossref": [ { "id": "ENSGALG00000000296", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSH3", "url": "https://www.orthodb.org/?gene=A0A3Q2TSH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U107", "url": "https://www.orthodb.org/?gene=A0A3Q2U107", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U2M2", "url": "https://www.orthodb.org/?gene=A0A3Q2U2M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TSH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U107", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U107", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U107-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U107-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2M2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAAGRPCASAVLVAPASSALSLPGDRERGRRPLPQGLPVYRRRGGGRPARGPDIRWRRRCWGGGGGDGCGCGRAGCRGARAARGSARAPRADRAGPARRSGAAMGSQVLQILRQGVWAALSGGWYQDPHQGAGVNALHLYLWLFLLGFPFTLYMALPSSMMIVAVYCPVIAALFIVLKMVNYRLHRALDEGEIVERNANERLDRGAKTEQSSVSAKRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGIDPNNQVGSGLSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSGQDLPRDNSDKVCLSNNQLVDQSKTSACDTEVASLITLHSHSYRKDHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDTVSELEASKPPSGSRESLAENSCISGVFQLDDILKSSSPQPLAKSGKSKSLKADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTISSYKSEHTSSTHIESVLSEHEEESPREEKKDGKKKDCGVDSEDDSSSTTDKRTSSERTAVEVSSISGVQEVKGSNASNEMHSQKGLSASASEEANKNPHANELTTQADRPPGKAAEQRDEQSEKLVLLVDSRASKETSGKQKEGDVRPKSSSLIHRTASTHKPSRRRTGKKRASSFDSSRHREYVSFRGVSGTKPHSAVFCHDEDSSDQSDLSRTSSMQSAHQFSSDSSSSTTSHSCQSPEGKYSALKTKYVSKERGGTDSENIHKTHVSSEGISKKRSTRRTSSTNSAKNRARVLSLDSGTVACLNDPNSLMTPGNIKQLTTSKSDLEAKEGEVLDELSLLGRASHLESVTRSRNSLPSQATFPEGEEQESASGAAQASEETVTFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSSSQAKVQSRSPSQAAVLSASTSLLVRNGSVHLEASHATASAVGGSSLHDGLGKFSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVHFYPHDLLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLQDHLQPQEEAAQKVKQYYRFWILPKLWISINFDRLTLLALFDRNREILENVLAVILAILVAFLGSVLLIEGFFKDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNISTTRFKLYGMAFTNPLLLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHVFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAMSYHLSRQSSDPSVLFSLVQSKFFPNSEDKNPEDPLSEVKDPLPEKLRNSVSERLQSDLIVCIVIGVLYFAIHVSTVFTVLQPILSYVLYALVGTVGFVTHYVLPQLRKQLPWHCFSHPLLKTKEYYQFEVRNAAHVMWFEKLHIWLLFIEKNVIYPLIVLNELSSSAKSIASPKKLDTELGALMITIAGLKLLRSSFSSPTCQYVTVIFTVLFFTFDYKSFTETMLLDLFFMSILFSKLWELFYKLRFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAAVSAFFSTPLNPFLGSAIFITSYARPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHLPHMLSFNAAFGQRWLAWEVLVTKYVLEGYSITDNSAASMLQVFDLRKILTTYYVKGIIYYVTTSPKLEEWLANETMQEGLRLCTDRNYVDVDPTFNPNIDEDYDHRLAGISRESFCMIYLNWIEYCCSRREKPLDSSKDSPLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSLKLHQDHFTSPDEYDDPSVLYEAITTHEENLVIAHEGDPAWRSAVLSNSPSLLALRHVMDDGTNEYKIIMLNKRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYSDSHEQLKEILGGAISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDAGGGASCTSNNATINESQSSVSQGGVNAPTGQGPGAVQHPPVAPHPGAHPTALPAAHPPAHPSTLGTSHSSHSVQSSLVRHSPARASVASHSSYCYGSRHSSLRTSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEPTGQSGVSMQHGLPSSSSSSQSIPACKQHALVGFLGTEGGSNAAETQSAGNASPANQMQAKKDDVIYRIQLMDPSQVLEGINVSKRKELQWPDEVIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPSSRSHIDKTILLVQIEDKYVAVVETGVLELGAEV", "length": 2457, "header": "tr|A0A3Q2TSH3-1|A0A3Q2TSH3_CHICK Isoform 1 of Pecanex-like protein OS=Gallus gallus OX=9031 GN=PCNX1 PE=3 SV=1 CANONICAL=A0A3Q2TSH3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3/entry", "sequence": { "sequence": "MKAAGRPCASAVLVAPASSALSLPGDRERGRRPLPQGLPVYRRRGGGRPARGPDIRWRRRCWGGGGGDGCGCGRAGCRGARAARGSARAPRADRAGPARRSGAAMGSQVLQILRQGVWAALSGGWYQDPHQGAGVNALHLYLWLFLLGFPFTLYMALPSSMMIVAVYCPVIAALFIVLKMVNYRLHRALDEGEIVERNANERLDRGAKTEQSSVSAKRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGIDPNNQVGSGLSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSGQDLPRDNSDKVCLSNNQLVDQSKTSACDTEVASLITLHSHSYRKDHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDTVSELEASKPPSGSRESLAENSCISGVFQLDDILKSSSPQPLAKSGKSKSLKADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTISSYKSEHTSSTHIESVLSEHEEESPREEKKDGKKKDCGVDSEDDSSSTTDKRTSSERTAVEVSSISGVQEVKGSNASNEMHSQKGLSASASEEANKNPHANELTTQADRPPGKAAEQRDEQSEKLVLLVDSRASKETSGKQKEGDVRPKSSSLIHRTASTHKPSRRRTGKKRASSFDSSRHREYVSFRGVSGTKPHSAVFCHDEDSSDQSDLSRTSSMQSAHQFSSDSSSSTTSHSCQSPEGKYSALKTKYVSKERGGTDSENIHKTHVSSEGISKKRSTRRTSSTNSAKNRARVLSLDSGTVACLNDPNSLMTPGNIKQLTTSKSDLEAKEGEVLDELSLLGRASHLESVTRSRNSLPSQATFPEGEEQESASGAAQASEETVTFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSSSQAKVQSRSPSQAAVLSASTSLLVRNGSVHLEASHATASAVGGSSLHDGLGKFSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVHFYPHDLLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLQDHLQPQEEAAQKVKQYYRFWILPKLWISINFDRLTLLALFDRNREILENVLAVILAILVAFLGSVLLIEGFFKDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNISTTRFKLYGMAFTNPLLLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHVFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAMSYHLSRQSSDPSVLFSLVQSKFFPNSEDKNPEDPLSEVKDPLPEKLRNSVSERLQSDLIVCIVIGVLYFAIHVSTVFTVLQPILSYVLYALVGTVGFVTHYVLPQLRKQLPWHCFSHPLLKTKEYYQFEVRNAAHVMWFEKLHIWLLFIEKNVIYPLIVLNELSSSAKSIASPKKLDTELGALMITIAGLKLLRSSFSSPTCQYVTVIFTVLFFTFDYKSFTETMLLDLFFMSILFSKLWELFYKLRFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAAVSAFFSTPLNPFLGSAIFITSYARPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHLPHMLSFNAAFGQRWLAWEVLVTKYVLEGYSITDNSAASMLQVFDLRKILTTYYVKGIIYYVTTSPKLEEWLANETMQEGLRLCTDRNYVDVDPTFNPNIDEDYDHRLAGISRESFCMIYLNWIEYCCSRREKPLDSSKDSPLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSLKLHQDHFTSPDEYDDPSVLYEAITTHEENLVIAHEGDPAWRSAVLSNSPSLLALRHVMDDGTNEYKIIMLNKRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYSDSHEQLKEILGGAISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDAGGGASCTSNNATINESQSSVSQGGVNAPTGQGPGAVQHPPVAPHPGAHPTALPAAHPPAHPSTLGTSHSSHSVQSSLVRHSPARASVASHSSYCYGSRHSSLRTSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEPTGQSGVSMQHGLPSSSSSSQSIPACKQHALVGFLGTEGGSNAAETQSAGNASPANQMQAKKDDVIYRIQLMDPSQVLEGINVSKRKELQWPDEVIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPSSRSHIDKTILLVQIEDKYVAVVETGVLELGAEV", "length": 2457, "header": "tr|A0A3Q2TSH3-1|A0A3Q2TSH3_CHICK Isoform 1 of Pecanex-like protein OS=Gallus gallus OX=9031 GN=PCNX1 PE=3 SV=1 CANONICAL=A0A3Q2TSH3-1" }, "locus": { "chromosome": "5", "start_pos": 26802534, "end_pos": 26720710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051610.1", "url": "https://www.ensembl.org/id/ENSGALT00010051610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030781.1", "url": "https://www.ensembl.org/id/ENSGALP00010030781.1" } ] } }, { "isoform_ac": "A0A3Q2U107-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U107/entry", "sequence": { "sequence": "MKAAGRPCASAVLVAPASSALSLPGDRERGRRPLPQGLPVYRRRGGGRPARGPDIRWRRRCWGGGGGDGCGCGRAGCRGARAARGSARAPRADRAGPARRSGAAMGSQVLQILRQGVWAALSGGWYQDPHQGAGVNALHLYLWLFLLGFPFTLYMALPSSMMIVAVYCPVIAALFIVLKMVNYRLHRALDEGEIVERNANERLDRGAKTEQSSVSAKRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGIDPNNQVGSGLSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSGQDLPRDNSDKVCLSNNQLVDQSKTSACDTEVASLITLHSHSYRKDHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDTVSELEASKPPSGSRESLAENSCISGVFQLDDILKSSSPQPLAKSGKSKSLKADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTISSYKSEHTSSTHIESVLSEHEEESPREEKKDGKKKDCGVDSEDDSSSTTDKRTSSERTAVEVSSISGVQEVKGSNASNEMHSQKGLSASASEEANKNPHANELTTQADRPPGKAAEQRDEQSEKLVLLVDSRASKETSGKQKEGDVRPKSSSLIHRTASTHKPSRRRTGKKRASSFDSSRHREYVSFRGVSGTKPHSAVFCHDEDSSDQSDLSRTSSMQSAHQFSSDSSSSTTSHSCQSPEGKYSALKTKYVSKERGGTDSENIHKTHVSSEGISKKRSTRRTSSTNSAKNRARVLSLDSGTVACLNDPNSLMTPGNIKQLTTSKSDLEAKEGEVLDELSLLGRASHLESVTRSRNSLPSQATFPEGEEQESASGGKFSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVHFYPHDLLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLQDHLQPQEEAAQKVKQYYRFWILPKLWISINFDRLTLLALFDRNREILENVLAVILAILVAFLGSVLLIEGFFKDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNISTTRFKLYGMAFTNPLLLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHVFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAMSYHLSRQSSDPSVLFSLVQSKFFPNSEDKNPEDPLSEVKDPLPEKLRNSVSERLQSDLIVCIVIGVLYFAIHVSTVFTVLQPILSYVLYALVGTVGFVTHYVLPQLRKQLPWHCFSHPLLKTKEYYQFEVRNAAHVMWFEKLHIWLLFIEKNVIYPLIVLNELSSSAKSIASPKKLDTELGALMITIAGLKLLRSSFSSPTCQYVTVIFTVLFFTFDYKSFTETMLLDLFFMSILFSKLWELFYKLRFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAAVSAFFSTPLNPFLGSAIFITSYARPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHLPHMLSFNAAFGQRWLAWEVLVTKYVLEGYSITDNSAASMLQVFDLRKILTTYYVKGIIYYVTTSPKLEEWLANETMQEGLRLCTDRNYVDVDPTFNPNIDEDYDHRLAGISRESFCMIYLNWIEYCCSRREKPLDSSKDSPLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSLKLHQDHFTSPDEYDDPSVLYEAITTHEENLVIAHEGDPAWRSAVLSNSPSLLALRHVMDDGTNEYKIIMLNKRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYSDSHEQLKEILGGAISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDAGGGASCTSNNATINESQSSVSQGGVNAPTGQGPGAVQHPPVAPHPGAHPTALPAAHPPAHPSTLGTSHSSHSVQSSLVRHSPARASVASHSSYCYGSRHSSLRTSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEPTGQSGVSMQHGLPSSSSSSQSIPACKQHALVGFLGTEGGSNAAETQSAGNASPANQMQAKKDDVIYRIQLMDPSQVLEGINVSKRKELQWPDEVIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPSSRSHIDKTILLVQIEDKYVAVVETGVLELGAEV", "length": 2351, "header": "tr|A0A3Q2U107-1|A0A3Q2U107_CHICK Computationally mapped isoform of Pecanex-like protein OS=Gallus gallus OX=9031 GN=PCNX1 PE=3 SV=1 CANONICAL=A0A3Q2TSH3-1" }, "locus": { "chromosome": "5", "start_pos": 26802534, "end_pos": 26720710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051623.1", "url": "https://www.ensembl.org/id/ENSGALT00010051623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030788.1", "url": "https://www.ensembl.org/id/ENSGALP00010030788.1" } ] } }, { "isoform_ac": "A0A3Q2U2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2M2/entry", "sequence": { "sequence": "MKAAGRPCASAVLVAPASSALSLPGDRERGRRPLPQGLPVYRRRGGGRPARGPDIRWRRRCWGGGGGDGCGCGRAGCRGARAARGSARAPRADRAGPARRSGAAMGSQVLQILRQGVWAALSGGWYQDPHQGAGVNALHLYLWLFLLGFPFTLYMALPSSMMIVAVYCPVIAALFIVLKMVNYRLHRALDEGEIVERNANERLDRGAKTEQSSVSAKRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGIDPNNQVGSGLSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSGQDLPRDNSDKVCLSNNQLVDQSKTSACDTEVASLITLHSHSYRKDHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDTVSELEASKPPSGSRESLAENSCISGVFQLDDILKSSSPQPLAKSGKSKSLKADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTISSYKSEHTSSTHIESVLSEHEEESPREEKKDGKKKDCGVDSEDDSSSTTDKRTSSERTAVEVSSISGVQEVKGSNASNEMHSQKGLSASASEEANKNPHANELTTQADRPPGKAAEQRDEQSEKLVLLVDSRASKETSGKQKEGDVRPKSSSLIHRTASTHKPSRRRTGKKRASSFDSSRHREYVSFRGVSGTKPHSAVFCHDEDSSDQSDLSRTSSMQSAHQFSSDSSSSTTSHSCQSPEGKYSALKTKYVSKERGGTDSENIHKTHVSSEGISKKRSTRRTSSTNSAKNRARVLSLDSGTVACLNDPNSLMTPGNIKQLTTSKSDLEAKEGEVLDELSLLGRASHLESVTRSRNSLPSQATFPEGEEQESASGAAQASEETVTFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSDTDSHVSSSTSVHFYPHDLLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLQDHLQPQEEAAQKVKQYYRFWILPKLWISINFDRLTLLALFDRNREILENVLAVILAILVAFLGSVLLIEGFFKDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNISTTRFKLYGMAFTNPLLLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHVFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAMSYHLSRQSSDPSVLFSLVQSKFFPNSEDKNPEDPLSEVKDPLPEKLRNSVSERLQSDLIVCIVIGVLYFAIHVSTVFTVLQPILSYVLYALVGTVGFVTHYVLPQLRKQLPWHCFSHPLLKTKEYYQFEVRNAAHVMWFEKLHIWLLFIEKNVIYPLIVLNELSSSAKSIASPKKLDTELGALMITIAGLKLLRSSFSSPTCQYVTVIFTVLFFTFDYKSFTETMLLDLFFMSILFSKLWELFYKLRFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAAVSAFFSTPLNPFLGSAIFITSYARPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHLPHMLSFNAAFGQRWLAWEVLVTKYVLEGYSITDNSAASMLQVFDLRKILTTYYVKGIIYYVTTSPKLEEWLANETMQEGLRLCTDRNYVDVDPTFNPNIDEDYDHRLAGISRESFCMIYLNWIEYCCSRREKPLDSSKDSPLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSLKLHQDHFTSPDEYDDPSVLYEAITTHEENLVIAHEGDPAWRSAVLSNSPSLLALRHVMDDGTNEYKIIMLNKRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYSDSHEQLKEILGGAISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDAGGGASCTSNNATINESQSSVSQGGVNAPTGQGPGAVQHPPVAPHPGAHPTALPAAHPPAHPSTLGTSHSSHSVQSSLVRHSPARASVASHSSYCYGSRHSSLRTSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEPTGQSGVSMQHGLPSSSSSSQSIPACKQHALVGFLGTEGGSNAAETQSAGNASPANQMQAKKDDVIYRIQLMDPSQVLEGINVSKRKELQWPDEVIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPSSRSHIDKTILLVQIEDKYVAVVETGVLELGAEV", "length": 2365, "header": "tr|A0A3Q2U2M2-1|A0A3Q2U2M2_CHICK Computationally mapped isoform of Pecanex-like protein OS=Gallus gallus OX=9031 GN=PCNX1 PE=3 SV=1 CANONICAL=A0A3Q2TSH3-1" }, "locus": { "chromosome": "5", "start_pos": 26802534, "end_pos": 26720710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051616.1", "url": "https://www.ensembl.org/id/ENSGALT00010051616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030785.1", "url": "https://www.ensembl.org/id/ENSGALP00010030785.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 906, "start_aa": "Thr", "end_pos": 906, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr906", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1257, "end_pos": 1259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1681, "end_pos": 1683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1822, "end_pos": 1824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2084, "end_pos": 2086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2164, "end_pos": 2166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2168, "end_pos": 2170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2345, "end_pos": 2347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2376, "end_pos": 2378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSH3" }, { "id": "PF05041", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pecanex C-terminal", "eco_id": "ECO_0000259", "start_pos": 1884, "end_pos": 2110, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 906 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1257, "end_pos": 1259 }, { "start_pos": 1681, "end_pos": 1683 }, { "start_pos": 1822, "end_pos": 1824 }, { "start_pos": 2084, "end_pos": 2086 }, { "start_pos": 2164, "end_pos": 2166 }, { "start_pos": 2168, "end_pos": 2170 }, { "start_pos": 2345, "end_pos": 2347 }, { "start_pos": 2376, "end_pos": 2378 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TSI6-1", "uniprot_ac": "A0A3Q2TSI6", "uniprot_id": "A0A3Q2TSI6_CHICK", "mass": { "chemical_mass": 93342.0, "monoisotopic_mass": 93342.0 }, "refseq": { "ac": "NP_001376283", "name": "DEP domain-containing protein 1A isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283" }, "gene_names": [ { "name": "DEPDC1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ] }, { "name": "DEPDC1", "type": "synonym", "evidence": [ { "id": "NP_001376283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283" } ] } ], "protein_names": [ { "name": "DEP domain-containing protein 1A", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6/entry#names_and_taxonomy" } ] }, { "name": "DEP domain-containing protein 1A isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001376283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283" } ] }, { "name": "DEP domain-containing protein 1A", "type": "synonym", "evidence": [ { "id": "NP_001376283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.1149.1, SRR13267654.244157.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Dec 15, 2020 this sequence version replaced XP_015146533.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DEPDC1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6", "locus": { "chromosome": "8", "start_pos": 28467764, "end_pos": 28479191, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023574", "url": "https://www.ensembl.org/id/ENSGALG00010023574" } ] } } ], "crossref": [ { "id": "A0A3Q2TSI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011275", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424710", "url": "https://www.ncbi.nlm.nih.gov/gene/424710", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HRRHMRT", "url": "https://omabrowser.org/oma/group/HRRHMRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSI6", "url": "https://www.orthodb.org/?gene=A0A3Q2TSI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVJ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZVJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A117", "url": "https://www.orthodb.org/?gene=A0A8V1A117", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A117", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A117", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A117-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A117-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRPAAPGPYRATELWNEITRYFRAGMPLRTHRQHFKKHGSCFTASEAADWLHEVLRSSSNFGPEVSRQQTVQLLRKFLKNHVIEDIKGRWGAENLEDNGALYRFPSTSPVKPLPAPCRQNENLQTFSKDRLLKLPHLSRRTLKKHQLLTPLDNVEKTKLDKTAENEEDALCRKEVSQEYVQETWRNIILIHLQTILGLPSLEEVLQPTQIVPEHVIYNMTHTSKHGVVILQNKSEDLPHWVLSAMKCLAYWPRNNDMSQPTYSGFERDVFRTVADYFVNLPEPLLTFEYYELFVNILVMCGFITIPNTCSGKHSVRDETRDPQSSKIPHLNSFKSTECLLLSLLRKEPKEIKEDYEASWKSSSEELADQTQRAKKLQQHKLASKQGSADNLIGGSCQNLSGFRNEQDLSLTFKTRCYSLERIGNTASRVHNKGELDSLRKTNVLSTRNEKQWLPCVSKTDSVLEFGFENTFQKQTDGSKRVSAPILQDRELFKENLKSKQICRSQGLLGSRSSRSCTSINVPIAEITVKPRSQLCGQGRPNTSVATSVGIRTEVSDITVSKRLCRSTIELSECSFTHSYVLTGTQNLLQPHLERIAVEALQICCLLLPPPNRRKMQLLMRMISRISENVDMPQLHDAMSTRSLMIQTFSRCVLCCAEEVDLDELLSTRLVSFLMDHQQEIFKVPTYLQVAVQDHLEYMKVAQCKYPGEEICAILPTYSYCEQITPQEFEEQKVSTSQAAVAELLENIIKDKNLSVKEKKKKLKQFQKEYPLIYQNRFPTTENEAMLFENKPTIKQPMLSLRKPKFRSLRH", "length": 812, "header": "tr|A0A3Q2TSI6-1|A0A3Q2TSI6_CHICK Isoform 1 of DEP domain-containing protein 1A OS=Gallus gallus OX=9031 GN=DEPDC1 PE=4 SV=1 CANONICAL=A0A3Q2TSI6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6/entry", "sequence": { "sequence": "MERRPAAPGPYRATELWNEITRYFRAGMPLRTHRQHFKKHGSCFTASEAADWLHEVLRSSSNFGPEVSRQQTVQLLRKFLKNHVIEDIKGRWGAENLEDNGALYRFPSTSPVKPLPAPCRQNENLQTFSKDRLLKLPHLSRRTLKKHQLLTPLDNVEKTKLDKTAENEEDALCRKEVSQEYVQETWRNIILIHLQTILGLPSLEEVLQPTQIVPEHVIYNMTHTSKHGVVILQNKSEDLPHWVLSAMKCLAYWPRNNDMSQPTYSGFERDVFRTVADYFVNLPEPLLTFEYYELFVNILVMCGFITIPNTCSGKHSVRDETRDPQSSKIPHLNSFKSTECLLLSLLRKEPKEIKEDYEASWKSSSEELADQTQRAKKLQQHKLASKQGSADNLIGGSCQNLSGFRNEQDLSLTFKTRCYSLERIGNTASRVHNKGELDSLRKTNVLSTRNEKQWLPCVSKTDSVLEFGFENTFQKQTDGSKRVSAPILQDRELFKENLKSKQICRSQGLLGSRSSRSCTSINVPIAEITVKPRSQLCGQGRPNTSVATSVGIRTEVSDITVSKRLCRSTIELSECSFTHSYVLTGTQNLLQPHLERIAVEALQICCLLLPPPNRRKMQLLMRMISRISENVDMPQLHDAMSTRSLMIQTFSRCVLCCAEEVDLDELLSTRLVSFLMDHQQEIFKVPTYLQVAVQDHLEYMKVAQCKYPGEEICAILPTYSYCEQITPQEFEEQKVSTSQAAVAELLENIIKDKNLSVKEKKKKLKQFQKEYPLIYQNRFPTTENEAMLFENKPTIKQPMLSLRKPKFRSLRH", "length": 812, "header": "tr|A0A3Q2TSI6-1|A0A3Q2TSI6_CHICK Isoform 1 of DEP domain-containing protein 1A OS=Gallus gallus OX=9031 GN=DEPDC1 PE=4 SV=1 CANONICAL=A0A3Q2TSI6-1" }, "locus": { "chromosome": "8", "start_pos": 28479071, "end_pos": 28469085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057389.1", "url": "https://www.ensembl.org/id/ENSGALT00010057389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034876.1", "url": "https://www.ensembl.org/id/ENSGALP00010034876.1" } ] } }, { "isoform_ac": "A0A8V0ZVJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVJ9/entry", "sequence": { "sequence": "MERRPAAPGPYRATELWNEITRYFRAGMPLRTHRQHFKKHGSCFTASEAADWLHEVLRSSSNFGPEVSRQQTVQLLRKFLKNHVIEDIKGRWGAENLEDNGALYRFPSTSPVKPLPAPCRQNENLQTFSKDRLLKLPHLSRRTLKKHQLLTPLDNVEKTKLDKTAENEEDALCRKEVSQEYVQETWRNIILIHLQTILGLPSLEEVLQPTQIVPEHVIYNMTHTSKHGVVILQNKSEDLPHWVLSAMKCLAYYLLQPHLERIAVEALQICCLLLPPPNRRKMQLLMRMISRISENVDMPQLHDAMSTRSLMIQTFSRCVLCCAEEVDLDELLSTRLVSFLMDHQQEIFKVPTYLQVAVQDHLEYMKVAQCKYPGEEICAILPTYSYCEQITPQEFEEQKVSTSQAAVAELLENIIKDKNLSVKEKKKKLKQFQKEYPLIYQNRFPTTENEAMLFENKPTIKQPMLSLRKPKFRSLRH", "length": 477, "header": "tr|A0A8V0ZVJ9-1|A0A3Q2TSI6_CHICK Computationally mapped isoform of DEP domain-containing protein 1A OS=Gallus gallus OX=9031 GN=DEPDC1 PE=4 SV=1 CANONICAL=A0A3Q2TSI6-1" }, "locus": { "chromosome": "8", "start_pos": 28479071, "end_pos": 28469085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057413.1", "url": "https://www.ensembl.org/id/ENSGALT00010057413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034888.1", "url": "https://www.ensembl.org/id/ENSGALP00010034888.1" } ] } }, { "isoform_ac": "A0A8V1A117-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A117/entry", "sequence": { "sequence": "MERRPAAPGPYRATELWNEITRYFRAGMPLRTHRQHFKKHGSCFTASEAADWLHEVLRSSSNFGPEVSRQQTVQLLRKFLKNHVIEDIKGRWGAENLEDNGALYRFPSTSPVKPLPAPCRQNENLQTFSKDRLLKLPHLSRRTLKKHQLLTPLDNVEKTKLDKTAENEEDALCRKEVSQEYVQETWRNIILIHLQTILGLPSLEEVLQPTQIVPEHVIYNMTHTSKHGVVIFFWVVNNDMSQPTYSGFERDVFRTVADYFVNLPEPLLTFEYYELFVNILDLLQPHLERIAVEALQICCLLLPPPNRRKMQLLMRMISRISENVDMPQLHDAMSTRSLMIQTFSRCVLCCAEEVDLDELLSTRLVSFLMDHQQEIFKVPTYLQVAVQDHLEYMKVAQCKYPGEEICAILPTYSYCEQITPQEFEEQKVSTSQAAVAELLENIIKDKNLSVKEKKKKLKQFQKEYPLIYQNRFPTTENEAMLFENKPTIKQPMLSLRKPKFRSLRH", "length": 505, "header": "tr|A0A8V1A117-1|A0A3Q2TSI6_CHICK Computationally mapped isoform of DEP domain-containing protein 1A OS=Gallus gallus OX=9031 GN=DEPDC1 PE=4 SV=1 CANONICAL=A0A3Q2TSI6-1" }, "locus": { "chromosome": "8", "start_pos": 28479071, "end_pos": 28469085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057408.1", "url": "https://www.ensembl.org/id/ENSGALT00010057408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034884.1", "url": "https://www.ensembl.org/id/ENSGALP00010034884.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B5S3-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "DEPDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENRSVPPGPYRATKLWNEVTTSFRSGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGKWGSENLDDNSQLFENTEKMNRDMISEDQENSVDNREINQKDVEEVWRHVVLIYLQTILGVSSLEEVINPKQVIPQYIMYNMTNTSKHGVVILQDKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYLTVSDRSSGLHKIQDDPQSSKILHLNSLNSFKSTECLLLSLLHKDKNKEESDTTERLQISDQGFQEKYAKKMQLVNLKYRRASANDIMGGSCHNLIGLSSMHGLCSNIKPRCYSLEGIIDLPGNSSKEVSSVFHQSVLNIEGQNNKHFLESKAKQESSLSLHSEQNIQKPLCVGFKRTSTLTIQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINMPVAEIIMKPNLGRGSTSVQTAMEGELRESSTTINKRLCKSTIELSENSLPPASSVLTGTQSLLQPHLERIAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPQLHDAMGTRSLMIHTFSRCVLRCAEEVDLDELLAARLVSFLMDHHQEILQVPSYLQTTVEEHLDYLRRGHIKNPSDVLIAPLPTYSYCKQISAQEFEEQKVSTSQAAIAELLENIIKNKSLPLKEKRKKLKQFQKEYPLIYQKRFPTSESEAALFDDKPTIKQPMLILRKPKFRSLRY", "length": 759 }, "evidence": [ { "id": "A0A3Q2TSI6", "url": "https://omabrowser.org/oma/group/A0A3Q2TSI6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MR79-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "Depdc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDRGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 808 }, "evidence": [ { "id": "A0A3Q2TSI6", "url": "https://omabrowser.org/oma/group/A0A3Q2TSI6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZGJ9-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "Depdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAVEAVDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTFPQRHTEIKKTSTEYFSKDRDSIFKLRNLSRKTPKKRGLQFSQENTEKINHERITNEDQENVPENKEISQEDVEDVWRYVTMIYLQTILGVPSIEELINPNQVIPQYIMYNMANTSKHGVVILQNKSEDLPHWVLSAMKCLANWPRCNDTNSLTYVGFERDVFKTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDKTSGIHKIQDDPRSSQIHDLSNLNSFKSTECLLLSLLSKDKSNEELDSTERLQRSDQGFQERCTKKMQLVNLRNRRASANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIIDMPVNSSEKKSSVFYLSVLNIEEHSSEQSLAPVPKQKSLLNLHSEEYAQQPHSVGFKRTSALTIEDQEDVCNGKYTSKQLCRSQSLLLRSSTRQNSSINKPVAEIIMKPNVGQGSTSVQSKLGGSITTINKRLCKSTIELSENSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDLPKLHEEIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQAAVEKHLDYIKKGHVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIAELLENIVRSKSLPLKEKRRKLKQFQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLNLRNPKLHSLRY", "length": 809 }, "evidence": [ { "id": "A0A3Q2TSI6", "url": "https://omabrowser.org/oma/group/A0A3Q2TSI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TB30-5", "protein_name": "DEP domain-containing protein 1A", "gene_name": "DEPDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYPELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESDSTERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRCCSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFSAGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQGSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR", "length": 811 }, "evidence": [ { "id": "A0A3Q2TSI6", "url": "https://omabrowser.org/oma/group/A0A3Q2TSI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIG0-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "Depdc1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAVEAIDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSESLDDNNQLFRFPATSPLKTFPQRHTEIKKTNTEYFSKDKDGIFKLRNLSQKTSKKRGLHFSQENTEKINHERITNEDLEIAPDNQEISQEDVEEVWRYVIMIYLQTILSLPSIEELLNPNQVIPQYIMYNMANTSKHGVVILQDKSDDLPHWVLSAMKCLANWPRSNDTNNLTYVGFERDVFKTIADYFLNLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIQDDPRSSKIHDLSNLNSFKSTECLLLSLLYKDKSNEELDSTKRLQRNDQGFQERCAKKMQLDNLRNRRASANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIVDRPVNSSEKKSSIFYQSVLNIEEQNSKQSLVSAPKQTPLFNLHSDENAQQPHCVGFNRTSALTVQDQEELCNEKYKSKQLCRSQSLLLRSSTRQNSCINKPVAEIIMKPNVGQGSTSELGESSTTINKRLCKSTIELSEKSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHEQIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQAAVEKHLDYIKKGNVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIAELLENIVRSKSLSLKEKRRKLKQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLNLRNPKLHSLRY", "length": 804 }, "evidence": [ { "id": "A0A3Q2TSI6", "url": "https://omabrowser.org/oma/group/A0A3Q2TSI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TSI6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 812, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TSI6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSI6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSI6" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 108, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 754, "end_pos": 756 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"yes" } }, { "uniprot_canonical_ac": "A0A3Q2TSR2-1", "uniprot_ac": "A0A3Q2TSR2", "uniprot_id": "A0A3Q2TSR2_CHICK", "mass": { "chemical_mass": 16939.0, "monoisotopic_mass": 16939.0 }, "refseq": { "ac": "XP_001231558", "name": "heat shock protein beta-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231558" }, "gene_names": [ { "name": "HSPB3", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2" } ] }, { "name": "HSPB3", "type": "synonym", "evidence": [ { "id": "XP_001231558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231558" } ] } ], "protein_names": [ { "name": "Heat shock protein family B (small) member 3", "type": "synonym", "evidence": [ { "id": "A0A3Q2TSR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2/entry#names_and_taxonomy" } ] }, { "name": "heat shock protein beta-3", "type": "synonym", "evidence": [ { "id": "XP_001231558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231558" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231558" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSPB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2", "locus": { "chromosome": "Z", "start_pos": 16984343, "end_pos": 16978264, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015006", "url": "https://www.ensembl.org/id/ENSGALG00010015006" } ] } } ], "crossref": [ { "id": "A0A3Q2TSR2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSR2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000047764", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000047764", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06477", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06477", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431593", "url": "https://www.ncbi.nlm.nih.gov/gene/431593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431593", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGPRMDE", "url": "https://omabrowser.org/oma/group/HGPRMDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSR2", "url": "https://www.orthodb.org/?gene=A0A3Q2TSR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47097", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47097", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47097:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47097:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231558", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAVIRHWVETPVRYQEQFAAEELEEHKLNHSLYALPGPFTAALSRRGQILESTDGAEATSQEEEKTGFQVLLDVVQFRPEDIIIQTFEGWLLIKAQHGPRMDEHGFISRSFTRQYKLPDGVENKDLSALFCHDGILVVEMKNSVGIN", "length": 149, "header": "tr|A0A3Q2TSR2-1|A0A3Q2TSR2_CHICK Isoform 1 of Heat shock protein family B (small) member 3 OS=Gallus gallus OX=9031 GN=HSPB3 PE=3 SV=1 CANONICAL=A0A3Q2TSR2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2/entry", "sequence": { "sequence": "MAEAVIRHWVETPVRYQEQFAAEELEEHKLNHSLYALPGPFTAALSRRGQILESTDGAEATSQEEEKTGFQVLLDVVQFRPEDIIIQTFEGWLLIKAQHGPRMDEHGFISRSFTRQYKLPDGVENKDLSALFCHDGILVVEMKNSVGIN", "length": 149, "header": "tr|A0A3Q2TSR2-1|A0A3Q2TSR2_CHICK Isoform 1 of Heat shock protein family B (small) member 3 OS=Gallus gallus OX=9031 GN=HSPB3 PE=3 SV=1 CANONICAL=A0A3Q2TSR2-1" }, "locus": { "chromosome": "Z", "start_pos": 16984343, "end_pos": 16983993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036089.1", "url": "https://www.ensembl.org/id/ENSGALT00010036089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020960.1", "url": "https://www.ensembl.org/id/ENSGALP00010020960.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431593", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SMX6-1", "protein_name": "Heat shock protein beta-3", "gene_name": "HSPB3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKIILRHLIETPVRYEEEFEARGLEDCRLDHALYALPGPTTLDLGKARATQAPPVDSAAEGPPQKGECRFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGIETKDLSATLCHDGILVVEVKDPVGTK", "length": 150 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HVF1-1", "protein_name": "Heat shock protein beta-3", "gene_name": "Hspb3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIILRHLIETPVRYQEEFEARGLEDCRLDHALYALPGPTIEDLRKVRGTPQALAEDSASTSTPPGEGKSRFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVETKDLSAILCHDGILVVEVKDPLATK", "length": 152 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12988-1", "protein_name": "Heat shock protein beta-3", "gene_name": "HSPB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKIILRHLIEIPVRYQEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAAETPPREGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVEIKDLSAVLCHDGILVVEVKDPVGTK", "length": 150 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KHU9-1", "protein_name": "Heat shock protein beta-3", "gene_name": "HSPB3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKIILRHLIETPVRYEQEFEARGLEDCRLDHALYALPGPTTVDLGKARAAQAPPVDAAEMPPQRGESRFQVLLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGIETKDLSAILCHDGILVVEVKDSAGTK", "length": 149 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QZ57-1", "protein_name": "Heat shock protein beta-3", "gene_name": "Hspb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKIILRHLIETPVRYQEEFEARGLEDCRLDHTLYALPGPTIEDLSKARGAGTPQALAEDSASTEKPPGEGKSRFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVETKDLSAILCHDGILVVEVKDSLGTK", "length": 154 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZ58-1", "protein_name": "Heat shock protein beta-3", "gene_name": "Hspb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIILRHLIETPVRYQEEFEARGLEDCRLDHALYALPGPTIEDLRKARGTPKALAEDSDSAETPPGEGKSRFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVETKDLSAILCHDGILVVEVKDPLETK", "length": 152 }, "evidence": [ { "id": "A0A3Q2TSR2", "url": "https://omabrowser.org/oma/group/A0A3Q2TSR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TSR2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TSR2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSR2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TSY7-1", "uniprot_ac": "A0A3Q2TSY7", "uniprot_id": "A0A3Q2TSY7_CHICK", "mass": { "chemical_mass": 102574.0, "monoisotopic_mass": 102574.0 }, "refseq": { "ac": "XP_015153175", "name": "serine/arginine repetitive matrix protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153175" }, "gene_names": [ { "name": "SRRM1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ] }, { "name": "SRRM1", "type": "synonym", "evidence": [ { "id": "XP_015153175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153175" } ] } ], "protein_names": [ { "name": "Serine/arginine repetitive matrix protein 1", "type": "recommended", "evidence": [ { "id": "A0A3Q2TSY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7/entry#names_and_taxonomy" } ] }, { "name": "serine/arginine repetitive matrix protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015153175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153175" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153175" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRRM1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7", "locus": { "chromosome": "23", "start_pos": 2890802, "end_pos": 2908253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015914", "url": "https://www.ensembl.org/id/ENSGALG00010015914" } ] } } ], "crossref": [ { "id": "A0A3Q2TSY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001283", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428216", "url": "https://www.ncbi.nlm.nih.gov/gene/428216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428216", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428216", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TSY7", "url": "https://www.orthodb.org/?gene=A0A3Q2TSY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMF4", "url": "https://www.orthodb.org/?gene=A0A8V0YMF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTV8", "url": "https://www.orthodb.org/?gene=A0A8V0YTV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVR1", "url": "https://www.orthodb.org/?gene=A0A8V0YVR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0K2", "url": "https://www.orthodb.org/?gene=A0A8V0Z0K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQL2", "url": "https://www.orthodb.org/?gene=E1BQL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23148:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23148:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015153175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153175", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQL2", "url": "https://www.uniprot.org/uniprotkb/E1BQL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRMQMEKRWQSPVMKSRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 902, "header": "tr|A0A3Q2TSY7-1|A0A3Q2TSY7_CHICK Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7/entry", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRMQMEKRWQSPVMKSRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 902, "header": "tr|A0A3Q2TSY7-1|A0A3Q2TSY7_CHICK Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2908154, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038354.1", "url": "https://www.ensembl.org/id/ENSGALT00010038354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022169.1", "url": "https://www.ensembl.org/id/ENSGALP00010022169.1" } ] } }, { "isoform_ac": "A0A8V0YMF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF4/entry", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 893, "header": "tr|A0A8V0YMF4-1|A0A3Q2TSY7_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2908154, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038349.1", "url": "https://www.ensembl.org/id/ENSGALT00010038349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022164.1", "url": "https://www.ensembl.org/id/ENSGALP00010022164.1" } ] } }, { "isoform_ac": "A0A8V0YTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTV8/entry", "sequence": { "sequence": "MYSSPHGSFNLILRQIVGCFFQITGLSSCHVSLQNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRMQMEKRWQSPVMKSRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 858, "header": "tr|A0A8V0YTV8-1|A0A3Q2TSY7_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2903085, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038356.1", "url": "https://www.ensembl.org/id/ENSGALT00010038356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022171.1", "url": "https://www.ensembl.org/id/ENSGALP00010022171.1" } ] } }, { "isoform_ac": "A0A8V0YVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR1/entry", "sequence": { "sequence": "MYSSPHGSFNLILRQIVGCFFQITGLSSCHVSLQNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 844, "header": "tr|A0A8V0YVR1-1|A0A3Q2TSY7_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2903085, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038342.1", "url": "https://www.ensembl.org/id/ENSGALT00010038342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022157.1", "url": "https://www.ensembl.org/id/ENSGALP00010022157.1" } ] } }, { "isoform_ac": "A0A8V0Z0K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0K2/entry", "sequence": { "sequence": "MMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 805, "header": "tr|A0A8V0Z0K2-1|A0A3Q2TSY7_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=1 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2902968, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038345.1", "url": "https://www.ensembl.org/id/ENSGALT00010038345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022160.1", "url": "https://www.ensembl.org/id/ENSGALP00010022160.1" } ] } }, { "isoform_ac": "E1BQL2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQL2/entry", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRHSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 888, "header": "tr|E1BQL2-1|A0A3Q2TSY7_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=3 SV=2 CANONICAL=A0A3Q2TSY7-1" }, "locus": { "chromosome": "23", "start_pos": 2908154, "end_pos": 2892349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038348.1", "url": "https://www.ensembl.org/id/ENSGALT00010038348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022163.1", "url": "https://www.ensembl.org/id/ENSGALP00010022163.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428216", "resource": "KEGG Pathway" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-GGA-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TSY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TSY7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 902, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TSY7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TSY7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TSY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSY7" }, { "id": "PS51025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWI", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 126, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 210 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 785, "end_pos": 787 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TTA1-1", "uniprot_ac": "A0A3Q2TTA1", "uniprot_id": "A0A3Q2TTA1_CHICK", "mass": { "chemical_mass": 7115.0, "monoisotopic_mass": 7115.0 }, "refseq": { "ac": "NP_001335440", "name": "gallinacin-14 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" }, "gene_names": [ { "name": "AvBD14", "type": "recommended", "evidence": [ { "id": "A0A3Q2TTA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTA1" } ] }, { "name": "AvBD14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "DEFB1", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "GAL14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "Gal-14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] } ], "protein_names": [ { "name": "Avian beta-defensin 14", "type": "synonym", "evidence": [ { "id": "A0A3Q2TTA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTA1/entry#names_and_taxonomy" } ] }, { "name": "Gallinacin-14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "beta-defensin 14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "defensin beta 1", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "gallinacin 14", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "gallinacin-14 precursor", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "name": "gallinacin-14-like", "type": "synonym", "evidence": [ { "id": "NP_001335440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01138827.1, HAEL01005216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000070.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001335440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" } ] }, { "annotation": "Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens.", "evidence": [ { "database": "RefSeq", "id": "NP_001335440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335440" }, { "database": "PubMed", "id": "32290685", "url": "https://glygen.org/publication/PubMed/32290685" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTA1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTA1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AvBD14", 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"A0A3Q2TTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6" } ] }, { "name": "LRRC18", "type": "synonym", "evidence": [ { "id": "XP_004942191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942191" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 18", "type": "synonym", "evidence": [ { "id": "A0A3Q2TTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 18", "type": "synonym", "evidence": [ { "id": "XP_004942191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942191" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942191" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC18", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6", "locus": { "chromosome": "6", "start_pos": 19280152, "end_pos": 19287425, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020115", "url": "https://www.ensembl.org/id/ENSGALG00010020115" } ] } } ], "crossref": [ { "id": "ENSGALG00000053919", "url": 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"id": "gga:101751830", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSQEDWR", "url": "https://omabrowser.org/oma/group/DSQEDWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TTF6", "url": "https://www.orthodb.org/?gene=A0A3Q2TTF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTF6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKGKGPKGKKITLKMAKNSIRISFDGGRRLDLSKMGITTFPKCILKLADVDELDLSRNMLKKIPNSIEKFQKLRWLDLHSNQLEELPKTVGTLQNLFYLNICNNKLTTKNLPEELNLLKNLRILNLGLNCLDSIPPTLGALKDLKELGLFDNFLTTIPNSVKRLPKLQKLNAERNPFPESKKEEYVDPIKRIESLYLVQEKDLCSSCLKTCQEERDKLNKFKNTTPCPSKKLSFPLLLTPNSTAMDNQEQWRLKDEDV", "length": 259, "header": "tr|A0A3Q2TTF6-1|A0A3Q2TTF6_CHICK Isoform 1 of Leucine rich repeat containing 18 OS=Gallus gallus OX=9031 GN=LRRC18 PE=4 SV=1 CANONICAL=A0A3Q2TTF6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6/entry", "sequence": { "sequence": "MAKGKGPKGKKITLKMAKNSIRISFDGGRRLDLSKMGITTFPKCILKLADVDELDLSRNMLKKIPNSIEKFQKLRWLDLHSNQLEELPKTVGTLQNLFYLNICNNKLTTKNLPEELNLLKNLRILNLGLNCLDSIPPTLGALKDLKELGLFDNFLTTIPNSVKRLPKLQKLNAERNPFPESKKEEYVDPIKRIESLYLVQEKDLCSSCLKTCQEERDKLNKFKNTTPCPSKKLSFPLLLTPNSTAMDNQEQWRLKDEDV", "length": 259, "header": "tr|A0A3Q2TTF6-1|A0A3Q2TTF6_CHICK Isoform 1 of Leucine rich repeat containing 18 OS=Gallus gallus OX=9031 GN=LRRC18 PE=4 SV=1 CANONICAL=A0A3Q2TTF6-1" }, "locus": { "chromosome": "6", "start_pos": 19283053, "end_pos": 19282277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048580.1", "url": "https://www.ensembl.org/id/ENSGALT00010048580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028671.1", "url": "https://www.ensembl.org/id/ENSGALP00010028671.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101751830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751830", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q66HD6-1", "protein_name": "Leucine-rich repeat-containing protein 18", "gene_name": "Lrrc18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGGKSPKGKKITLNVAKNCIKITFDGRKRLDLSKMGITTFPKCILRLNEIDELDLSRNMIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRLTTNGLPVELNQLKNIRTVNLGLNHLDSVPTTLGALKELHEVGLHDNLLTSIPAGISKLPKLKKLNVKRNPFPKPDESDMFVDSIKRLENLYLVEEKDLCSSCLQKCQQARDKLNKIRSMAPSAPRKAIFSNLVSPNSTAKESQEEWSV", "length": 256 }, "evidence": [ { "id": "A0A3Q2TTF6", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N456-1", "protein_name": "Leucine-rich repeat-containing protein 18", "gene_name": "LRRC18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKGEKGPKGKKITLKVARNCIKITFDGKKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKPGESEIFIDSIRRLENLYVVEEKDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNLISPNSMAKDSWEDWRIRLTSS", "length": 261 }, "evidence": [ { "id": "A0A3Q2TTF6", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQ07-1", "protein_name": "Leucine-rich repeat-containing protein 18", "gene_name": "Lrrc18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKGGKGPKGKKITLNVAKNCIKITFDGRKRLDLSKMGITTFPKCILRLSDIDELDLSRNMIRKIPDSIAKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRLTTNGLPVELNQLKNIRTVNLGLNHLDSVPTTLGALKELHEVGLHDNLLTTIPASIAKLPKLKKLNIKRNPFPNADESEMFVDSIKRLENLYLVEEKDMCSSCLQRCQQARDKLNKIKSMAPSAPRKALFSNLVSPNSTAKDAQEEWRLRSPSTF", "length": 262 }, "evidence": [ { "id": "A0A3Q2TTF6", "url": "https://omabrowser.org/oma/group/A0A3Q2TTF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TTF6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TTF6" }, { "id": "PF23598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disease resistance R13L4/SHOC-2-like LRR", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 188, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 242, "end_pos": 244 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TU83-1", "uniprot_ac": "A0A3Q2TU83", "uniprot_id": "A0A3Q2TU83_CHICK", "mass": { "chemical_mass": 63651.0, "monoisotopic_mass": 63651.0 }, "refseq": { "ac": "XP_015134939", "name": "far upstream element-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134939" }, "gene_names": [ { "name": "FUBP3", "type": "recommended", "evidence": [ { "id": "A0A3Q2TU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ] }, { "name": "FUBP3", "type": "synonym", "evidence": [ { "id": "XP_015134939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134939" } ] } ], "protein_names": [ { "name": "Far upstream element binding protein 3", "type": "synonym", "evidence": [ { "id": "A0A3Q2TU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83/entry#names_and_taxonomy" } ] }, { "name": "far upstream element-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134939" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134939" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FUBP3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83", "locus": { "chromosome": "17", "start_pos": 6554744, "end_pos": 6517312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028889", "url": "https://www.ensembl.org/id/ENSGALG00010028889" } ] } } ], "crossref": [ { "id": "A0A3Q2TU83", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TU83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003941", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003941", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22480", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22480", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22483", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22483", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22486", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22486", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417184", "url": "https://www.ncbi.nlm.nih.gov/gene/417184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HNDVDSN", "url": "https://omabrowser.org/oma/group/HNDVDSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TU83", "url": "https://www.orthodb.org/?gene=A0A3Q2TU83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AB26", "url": "https://www.orthodb.org/?gene=A0A3Q3AB26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAJ3", "url": "https://www.orthodb.org/?gene=A0A8V1AAJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAJ8", "url": "https://www.orthodb.org/?gene=A0A8V1AAJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFX5", "url": "https://www.orthodb.org/?gene=A0A8V1AFX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHY8", "url": "https://www.orthodb.org/?gene=A0A8V1AHY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHZ3", "url": "https://www.orthodb.org/?gene=A0A8V1AHZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK70", "url": "https://www.orthodb.org/?gene=A0A8V1AK70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AB26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AB26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AB26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AB26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGLRVSGLHGAQIRDTERIGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPNHNGTQSGQVEFTKAWEDYYRKLGQQSQQQNSHPDYSKAWEEYYKKQSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 586, "header": "tr|A0A3Q2TU83-1|A0A3Q2TU83_CHICK Isoform 1 of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TU83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGLRVSGLHGAQIRDTERIGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPNHNGTQSGQVEFTKAWEDYYRKLGQQSQQQNSHPDYSKAWEEYYKKQSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 586, "header": "tr|A0A3Q2TU83-1|A0A3Q2TU83_CHICK Isoform 1 of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069874.1", "url": "https://www.ensembl.org/id/ENSGALT00010069874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043000.1", "url": "https://www.ensembl.org/id/ENSGALP00010043000.1" } ] } }, { "isoform_ac": "A0A3Q3AB26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AB26/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGLRVSGLHGAQIRDTERIGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPSQQSQQQNSHPDYSKAWEEYYKKQSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 563, "header": "tr|A0A3Q3AB26-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069875.1", "url": "https://www.ensembl.org/id/ENSGALT00010069875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043001.1", "url": "https://www.ensembl.org/id/ENSGALP00010043001.1" } ] } }, { "isoform_ac": "A0A8V1AAJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ3/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQVSAGQGRAGGGRRPRGAARPRGRPEGVLNRLLPLTGLRVSGLHGAQIRDTERSMCEQSSMAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQHEQRDAEGWDASPLQAALPELSCWGCGHWRSTTLKQ", "length": 569, "header": "tr|A0A8V1AAJ3-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553017, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069873.1", "url": "https://www.ensembl.org/id/ENSGALT00010069873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042999.1", "url": "https://www.ensembl.org/id/ENSGALP00010042999.1" } ] } }, { "isoform_ac": "A0A8V1AAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAJ8/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGLRVSGLHGAQIRDTERIGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGWSSGVHDAGLGQYLPDVAAAWTASPKSCCQRCFSGELPAGLHDGLGRVLQTAGCLLWADTRAGAGPQPGAVEQRPRGHRRYLVSPSESLWKKTFL", "length": 539, "header": "tr|A0A8V1AAJ8-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553251, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069878.1", "url": "https://www.ensembl.org/id/ENSGALT00010069878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043004.1", "url": "https://www.ensembl.org/id/ENSGALP00010043004.1" } ] } }, { "isoform_ac": "A0A8V1AFX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX5/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 521, "header": "tr|A0A8V1AFX5-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069880.1", "url": "https://www.ensembl.org/id/ENSGALT00010069880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043006.1", "url": "https://www.ensembl.org/id/ENSGALP00010043006.1" } ] } }, { "isoform_ac": "A0A8V1AHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY8/entry", "sequence": { "sequence": "MQQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGGLRVSGLHGAQIRDTERIGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 513, "header": "tr|A0A8V1AHY8-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6523483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069872.1", "url": "https://www.ensembl.org/id/ENSGALT00010069872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042998.1", "url": "https://www.ensembl.org/id/ENSGALP00010042998.1" } ] } }, { "isoform_ac": "A0A8V1AHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ3/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRAVITEDFKVPDKMVGFIIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPNHNGTQSGQVEFTKAWEDYYRKLGHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 545, "header": "tr|A0A8V1AHZ3-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069877.1", "url": "https://www.ensembl.org/id/ENSGALT00010069877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043003.1", "url": "https://www.ensembl.org/id/ENSGALP00010043003.1" } ] } }, { "isoform_ac": "A0A8V1AK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK70/entry", "sequence": { "sequence": "MAELAQGQSAAPVGIKPEGFVDALHRVRQIAAKIGDIPHLNNSTTLVDPSVYGYGVQKRPLDDGVIGRGGEQISRIQIESGCKIQIAPDSGGMPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDVDGNSTIQEILIPASKVGLVIGKGGETIKQLQERTGVKMIMIQDGPMPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRNDFSSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERVAQVMGLPDRCQHAAHIISELILTAQERDGFGSLAVARGRGRGRGDWSVGTPGGMQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPGVRIFTIRGVPQQIELARHLIDEKVGGTSMGGPGGFGQSPFNQAPTTPHQNGPQAFMTQGWGSTYQTWQQPGQQVPSHAASAASQASSQPDYTMAWAEYYRQQAAYYGQTLGQAQAHSQEQ", "length": 494, "header": "tr|A0A8V1AK70-1|A0A3Q2TU83_CHICK Computationally mapped isoform of Far upstream element binding protein 3 OS=Gallus gallus OX=9031 GN=FUBP3 PE=1 SV=1 CANONICAL=A0A3Q2TU83-1" }, "locus": { "chromosome": "17", "start_pos": 6553177, "end_pos": 6517392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069876.1", "url": "https://www.ensembl.org/id/ENSGALT00010069876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043002.1", "url": "https://www.ensembl.org/id/ENSGALP00010043002.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8B7-1", "protein_name": "Far upstream element binding protein 3", "gene_name": "Fubp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELVQGQSAPVGLKAEDFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRAVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDGNSTIQELLIPASKVGLVIGKGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDPFKVQQAREMVLEIIREKDQADFRGVRSDFTSRAGGGSIEVSVPRFVVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAARIINELILTAQEREILGGLTGTRGRGRGRGDWSVGTPGGIQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPNLRIFTIRGAPQQIEVARHLIDEKVGGASLGAPTAFGQSPFSQPPAAPHQNTFPPRAFPNIAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQNSQPDYSKAWEDYYKKQGHTTSAAPQASSPPDYTMAWAEYYRQQAAFYGQTLGQAQAHSQEQ", "length": 569 }, "evidence": [ { "id": "A0A3Q2TU83", "url": "https://omabrowser.org/oma/group/A0A3Q2TU83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AJ72-1", "protein_name": "Far upstream element (FUSE) binding protein 3", "gene_name": "Fubp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRALDDGVGNQLGALVHQRAVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDMDGNSTIQELLIPASKVGLVIGKGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDPFKVQQAREMVLEIIREKDQADFRGVRSDFTSRAGGGSIEVSVPRFVVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAARIINELILTAQEREILGGLTVTRGRGRGRSDWSVGTPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNTDPNLRIFTIRGAPQQMEVARHLIDEKVGGASLGAPAAFGQSPFSQPPAAPHQNTFPPRGFPNIAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQNSQPDYSKAWEDYYKKQSHPTSAAPQASSPPDYTMAWAEYYRQQAAFYGQTLGQAQAHSQEQ", "length": 569 }, "evidence": [ { "id": "A0A3Q2TU83", "url": "https://omabrowser.org/oma/group/A0A3Q2TU83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96I24-1", "protein_name": "Far upstream element-binding protein 3", "gene_name": "FUBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSPPDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ", "length": 572 }, "evidence": [ { "id": "A0A3Q2TU83", "url": "https://omabrowser.org/oma/group/A0A3Q2TU83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TU83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TU83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 586, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TU83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TU83" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TU83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU83" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 164, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TUH4-1", "uniprot_ac": "A0A3Q2TUH4", "uniprot_id": "A0A3Q2TUH4_CHICK", "mass": { "chemical_mass": 54633.0, "monoisotopic_mass": 54633.0 }, "refseq": {}, "gene_names": [ { "name": "TNIP3", "type": "recommended", "evidence": [ { "id": "A0A3Q2TUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ] } ], "protein_names": [ { "name": "TNFAIP3 interacting protein 3", "type": "synonym", "evidence": [ { "id": "A0A3Q2TUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNIP3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4", "locus": { "chromosome": "4", "start_pos": 53688292, "end_pos": 53609610, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005357", "url": "https://www.ensembl.org/id/ENSGALG00010005357" } ] } } ], "crossref": [ { "id": "A0A3Q2TUH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TUH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011961", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011961", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771693", "url": "https://www.ncbi.nlm.nih.gov/gene/771693", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TUH4", "url": "https://www.orthodb.org/?gene=A0A3Q2TUH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGM0", "url": "https://www.orthodb.org/?gene=A0A8V0XGM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGN5", "url": "https://www.orthodb.org/?gene=A0A8V0XGN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XKQ3", "url": "https://www.orthodb.org/?gene=A0A8V0XKQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XN54", "url": "https://www.orthodb.org/?gene=A0A8V0XN54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQW0", "url": "https://www.orthodb.org/?gene=A0A8V0XQW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTB3", "url": "https://www.orthodb.org/?gene=A0A8V0XTB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTD6", "url": "https://www.orthodb.org/?gene=A0A8V0XTD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTE1", "url": "https://www.orthodb.org/?gene=A0A8V0XTE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31882:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31882:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689896", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XN54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XN54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHVYFLVNLRIYMNSKNLKQFISFRMNTNNHKNTFHNISSICIHCENFKRKNKEAEDLLELCSHQHAEMERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 465, "header": "tr|A0A3Q2TUH4-1|A0A3Q2TUH4_CHICK Isoform 1 of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4/entry", "sequence": { "sequence": "MKHVYFLVNLRIYMNSKNLKQFISFRMNTNNHKNTFHNISSICIHCENFKRKNKEAEDLLELCSHQHAEMERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 465, "header": "tr|A0A3Q2TUH4-1|A0A3Q2TUH4_CHICK Isoform 1 of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53641522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012724.1", "url": "https://www.ensembl.org/id/ENSGALT00010012724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007288.1", "url": "https://www.ensembl.org/id/ENSGALP00010007288.1" } ] } }, { "isoform_ac": "A0A8V0XGM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGM0/entry", "sequence": { "sequence": "MNTLPKMIHCENFKRKNKEAEDLLELCSHQHAEMERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 429, "header": "tr|A0A8V0XGM0-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53633515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012726.1", "url": "https://www.ensembl.org/id/ENSGALT00010012726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007290.1", "url": "https://www.ensembl.org/id/ENSGALP00010007290.1" } ] } }, { "isoform_ac": "A0A8V0XGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGN5/entry", "sequence": { "sequence": "MCCNSLPESIGSGVTDPQNQWIHCENFKRKNKEAEDLLELCSHQHAEMESRCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 444, "header": "tr|A0A8V0XGN5-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53609737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012741.1", "url": "https://www.ensembl.org/id/ENSGALT00010012741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007305.1", "url": "https://www.ensembl.org/id/ENSGALP00010007305.1" } ] } }, { "isoform_ac": "A0A8V0XKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKQ3/entry", "sequence": { "sequence": "MEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 329, "header": "tr|A0A8V0XKQ3-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53659754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012715.1", "url": "https://www.ensembl.org/id/ENSGALT00010012715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007279.1", "url": "https://www.ensembl.org/id/ENSGALP00010007279.1" } ] } }, { "isoform_ac": "A0A8V0XN54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN54/entry", "sequence": { "sequence": "MLTHRCGCARRNKRSLKAVPLSMIQEMHEETRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 379, "header": "tr|A0A8V0XN54-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53651639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012713.1", "url": "https://www.ensembl.org/id/ENSGALT00010012713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007277.1", "url": "https://www.ensembl.org/id/ENSGALP00010007277.1" } ] } }, { "isoform_ac": "A0A8V0XQW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQW0/entry", "sequence": { "sequence": "MIHCENFKRKNKEAEDLLELCSHQHAEMERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 423, "header": "tr|A0A8V0XQW0-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53641851, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012719.1", "url": "https://www.ensembl.org/id/ENSGALT00010012719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007283.1", "url": "https://www.ensembl.org/id/ENSGALP00010007283.1" } ] } }, { "isoform_ac": "A0A8V0XTB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTB3/entry", "sequence": { "sequence": "MEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANECPSASFSVEKFVVRKRSPSLTAFDLKMCTLKTAS", "length": 354, "header": "tr|A0A8V0XTB3-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687514, "end_pos": 53659754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012712.1", "url": "https://www.ensembl.org/id/ENSGALT00010012712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007276.1", "url": "https://www.ensembl.org/id/ENSGALP00010007276.1" } ] } }, { "isoform_ac": "A0A8V0XTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTD6/entry", "sequence": { "sequence": "MERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQVQIYEEDFRKERSDRERLNEEKEALQKANERLQTQLNKLNSQMRTCLKGKEQQERQLQQQSKDIPVQSERLTYPPPLFLSPCVNYGRCGLVLHYQDPRVHPVSRRAQEQQQHSPDCQWYVPDQFPPDVQHKANAPIKRNSQLVPS", "length": 398, "header": "tr|A0A8V0XTD6-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53681056, "end_pos": 53642038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012732.1", "url": "https://www.ensembl.org/id/ENSGALT00010012732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007296.1", "url": "https://www.ensembl.org/id/ENSGALP00010007296.1" } ] } }, { "isoform_ac": "A0A8V0XTE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTE1/entry", "sequence": { "sequence": "MERCESKELDVEIRNLIERSGTSKSREDLEPIAQGSVNHQRTSCSPKTRSETNAQGHLGSTWADVSEMEAPADPLESKHVLPSKQKTVLAKSQERHILSLERQKQELLEVNKQWDLQFRTMKELYEKQLAEVKAKLHLSERRVSDLEEERHRHPPEKERLQFLDRDRPSQETKETKVLSEALHEMKEENKLLKQKNASLIRKQEHYECEISRLNKALLDVLKKNCSVLGTPSEAGDKNSLDDMKTQLEVLKQQPDCQWYVPDQFPPDVQHKANDLSSEKGAHR", "length": 283, "header": "tr|A0A8V0XTE1-1|A0A3Q2TUH4_CHICK Computationally mapped isoform of TNFAIP3 interacting protein 3 OS=Gallus gallus OX=9031 GN=TNIP3 PE=4 SV=1 CANONICAL=A0A3Q2TUH4-1" }, "locus": { "chromosome": "4", "start_pos": 53687470, "end_pos": 53642038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012737.1", "url": "https://www.ensembl.org/id/ENSGALT00010012737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007301.1", "url": "https://www.ensembl.org/id/ENSGALP00010007301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5689896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689896", "resource": "Reactome", "description": "Ovarian tumor domain proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" }, { "name": "toll-like receptor 4 signaling pathway", "id": "GO:0034142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" }, { "name": "MyD88-independent toll-like receptor signaling pathway", "id": "GO:0002756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002756", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TUH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 465, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TUH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TUH4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUH4" }, { "id": "PF16516", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16516" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NF-kappa-B essential modulator NEMO CC2-LZ", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 362, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "uniprot_ac": "A0A3Q2TUK0", "uniprot_id": "A0A3Q2TUK0_CHICK", "mass": { "chemical_mass": 33810.0, "monoisotopic_mass": 33810.0 }, "refseq": { "ac": "XP_040520759", "name": "SUN domain-containing protein 3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520759" }, "gene_names": [ { "name": "LOC121109925", "type": "recommended", "evidence": [ { "id": "A0A3Q2TUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ] }, { "name": "LOC121109925", "type": "synonym", "evidence": [ { "id": "XP_040520759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520759" } ] } ], "protein_names": [ { "name": "SUN domain-containing protein 3-like", "type": "synonym", "evidence": [ { "id": "XP_040520759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520759" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2TUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040520759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520759" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121109925", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TUK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TUK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000049315", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049315", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "121109925", "url": "https://www.ncbi.nlm.nih.gov/gene/121109925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VICEYCT", "url": "https://omabrowser.org/oma/group/VICEYCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TUK0", "url": "https://www.orthodb.org/?gene=A0A3Q2TUK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040520759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306, "header": "tr|A0A3Q2TUK0-1|A0A3Q2TUK0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121109925 PE=4 SV=1 CANONICAL=A0A3Q2TUK0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TUK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0/entry", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306, "header": "tr|A0A3Q2TUK0-1|A0A3Q2TUK0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121109925 PE=4 SV=1 CANONICAL=A0A3Q2TUK0-1" }, "locus": { "chromosome": "2", "start_pos": 81441117, "end_pos": 81436734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018615.1", "url": "https://www.ensembl.org/id/ENSGALT00010018615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010185.1", "url": "https://www.ensembl.org/id/ENSGALP00010010185.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A3Q2TUK0", "url": "https://omabrowser.org/oma/group/A0A3Q2TUK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TUK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TUK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TUK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TUQ4-1", "uniprot_ac": "A0A3Q2TUQ4", "uniprot_id": "A0A3Q2TUQ4_CHICK", "mass": { "chemical_mass": 36966.0, "monoisotopic_mass": 36966.0 }, "refseq": { "ac": "XP_046754510", "name": "lysophosphatidic acid receptor 6-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754510" }, "gene_names": [ { "name": "LOC101748451", "type": "recommended", "evidence": [ { "id": "A0A3Q2TUQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4" } ] }, { "name": "LOC101748451", "type": "synonym", "evidence": [ { "id": "XP_046754510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754510" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q2TUQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4/entry#names_and_taxonomy" } ] }, { "name": "lysophosphatidic acid receptor 6-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046754510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754510" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754510" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101748451", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TUQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TUQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005543", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101748451", "url": "https://www.ncbi.nlm.nih.gov/gene/101748451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LDGVCYY", "url": "https://omabrowser.org/oma/group/LDGVCYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TUQ4", "url": "https://www.orthodb.org/?gene=A0A3Q2TUQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3Y1", "url": "https://www.orthodb.org/?gene=E1C3Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046754510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Y1", "url": "https://www.uniprot.org/uniprotkb/E1C3Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Y1-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFFNFSIPGDMNDTCTNSSINPRVELFQLIMYTPTFILGLLFNVMALSFLFFPAKKLSESTVYLIALIFLDTLLLFTLPFKIISYHLQNKWKLGSVFCSILESLYFINMYGSILISLCICVDRYIAIQHPFMAPTLRSTKKAALVCVVICLGISAGSVSTSQFHEESYNISSCFHNFSKSTWENTGLIIGLEMIFFGSMVAMAFCTTQIIRCLRNHRKSDNPQTHMTRAEKVVVTNFVTFLVCFTPYHVTFFLYFLVRNSIMHIPCHTVLRDILQVTLCWANLNCCLDAVCYYFVLKESAEGSLQNKARNHTEESFDPHTER", "length": 323, "header": "tr|A0A3Q2TUQ4-1|A0A3Q2TUQ4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101748451 PE=4 SV=1 CANONICAL=A0A3Q2TUQ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUQ4/entry", "sequence": { "sequence": "MIFFNFSIPGDMNDTCTNSSINPRVELFQLIMYTPTFILGLLFNVMALSFLFFPAKKLSESTVYLIALIFLDTLLLFTLPFKIISYHLQNKWKLGSVFCSILESLYFINMYGSILISLCICVDRYIAIQHPFMAPTLRSTKKAALVCVVICLGISAGSVSTSQFHEESYNISSCFHNFSKSTWENTGLIIGLEMIFFGSMVAMAFCTTQIIRCLRNHRKSDNPQTHMTRAEKVVVTNFVTFLVCFTPYHVTFFLYFLVRNSIMHIPCHTVLRDILQVTLCWANLNCCLDAVCYYFVLKESAEGSLQNKARNHTEESFDPHTER", "length": 323, "header": "tr|A0A3Q2TUQ4-1|A0A3Q2TUQ4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101748451 PE=4 SV=1 CANONICAL=A0A3Q2TUQ4-1" }, "locus": { "chromosome": "9", "start_pos": 5037592, "end_pos": 5036624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062708.1", "url": "https://www.ensembl.org/id/ENSGALT00010062708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038764.1", "url": "https://www.ensembl.org/id/ENSGALP00010038764.1" } ] } }, { "isoform_ac": "E1C3Y1-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Y1/entry", "sequence": { "sequence": "MNDTCTNSSINPRVELFQLIMYTPTFILGLLFNVMALSFLFFPAKKLSESTVYLIALIFLDTLLLFTLPFKIISYHLQNKWKLGSVFCSILESLYFINMYGSILISLCICVDRYIAIQHPFMAPTLRSTKKAALVCVVICLGISAGSVSTSQFHEESYNISSCFHNFSKSTWENTGLIIGLEMIFFGSMVAMAFCTTQIIRCLRNHRKSDNPQTHMTRAEKVVVTNFVTFLVCFTPYHVTFFLYFLVRNSIMHIPCHTVLRDILQVTLCWANLNCCLDAVCYYFVLKESAEGSLQNKARNHTEESFDPHTER", "length": 312, "header": "tr|E1C3Y1-1|A0A3Q2TUQ4_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101748451 PE=4 SV=4 CANONICAL=A0A3Q2TUQ4-1" }, "locus": { "chromosome": "9", "start_pos": 5037592, "end_pos": 5036657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062715.1", "url": "https://www.ensembl.org/id/ENSGALT00010062715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038767.1", "url": "https://www.ensembl.org/id/ENSGALP00010038767.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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"MATQDPSQVGARGSRQARDVNAWGEGGAVSQHLCAGDREAAGTGVSPLCQLLPWALAVPSKEPLCLQEPVSFADVAVYFSREEWALLDPAQRVLYRDVMLETYECVASLAPKPAMISLLEGGEEPWIPDVRGLEDTAGDLSPAGHGVAAAPDVLQKCDVTEGQWGIASVGEIRKAIQEDLEQGEHLKQQRGNPPGETARSPQDSSTGQKQPEGARSEEVCQEKRQNPNAECGNSLKRCSVLLNHHCVRSVKRLYKCSDCTKSFKWKSHLTCHQRIHTDERPFKCPDCPKCFKTNSHLTGHQRIHKGEKPIKYCECGKGFKYSSILQRHQRIHTGERPFKCPECPKSFKNSFHLTCHQRIHTGERPFKCCECGKHFKYSFVLKRHQRMHTAVGPFKCSECGKGFKFGYELQHHNRIHTEKRPFKCPECSKSFKSKSQLTYHQRTHTGERPFKCRECEMSFKYSFVLKRHQRIHTGERSIKCVARVYGVLRPGSVTDGAGGPTDPRPRKGIMGKGKRGKGKREKGRKTGLTSKQWQ", "length": 534, "header": "tr|A0A3Q2TVZ6-1|A0A3Q2TVZ6_CHICK Isoform 1 of MHCY region zinc finger protein 2 OS=Gallus gallus OX=9031 GN=ZNFY2 PE=3 SV=1 CANONICAL=A0A3Q2TVZ6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6/entry", "sequence": { "sequence": "MATQDPSQVGARGSRQARDVNAWGEGGAVSQHLCAGDREAAGTGVSPLCQLLPWALAVPSKEPLCLQEPVSFADVAVYFSREEWALLDPAQRVLYRDVMLETYECVASLAPKPAMISLLEGGEEPWIPDVRGLEDTAGDLSPAGHGVAAAPDVLQKCDVTEGQWGIASVGEIRKAIQEDLEQGEHLKQQRGNPPGETARSPQDSSTGQKQPEGARSEEVCQEKRQNPNAECGNSLKRCSVLLNHHCVRSVKRLYKCSDCTKSFKWKSHLTCHQRIHTDERPFKCPDCPKCFKTNSHLTGHQRIHKGEKPIKYCECGKGFKYSSILQRHQRIHTGERPFKCPECPKSFKNSFHLTCHQRIHTGERPFKCCECGKHFKYSFVLKRHQRMHTAVGPFKCSECGKGFKFGYELQHHNRIHTEKRPFKCPECSKSFKSKSQLTYHQRTHTGERPFKCRECEMSFKYSFVLKRHQRIHTGERSIKCVARVYGVLRPGSVTDGAGGPTDPRPRKGIMGKGKRGKGKREKGRKTGLTSKQWQ", "length": 534, "header": "tr|A0A3Q2TVZ6-1|A0A3Q2TVZ6_CHICK Isoform 1 of MHCY region zinc finger protein 2 OS=Gallus gallus OX=9031 GN=ZNFY2 PE=3 SV=1 CANONICAL=A0A3Q2TVZ6-1" }, "locus": { "chromosome": "16", "start_pos": 1672069, "end_pos": 1669731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008539.1", "url": "https://www.ensembl.org/id/ENSGALT00010008539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004997.1", "url": "https://www.ensembl.org/id/ENSGALP00010004997.1" } ] } }, { "isoform_ac": "A0A8V0XJS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJS1/entry", "sequence": { "sequence": "MATQDPSQLLPWALAVPSKEPLCLQEPVSFADVAVYFSREEWALLDPAQRVLYRDVMLETYECVASLAPKPAMISLLEGGEEPWIPDVRGLEDTAGDLSPAGHGVAAAPDVLQKCDVTEGQWGIASVGEIRKAIQEDLEQGEHLKQQRGNPPGETARSPQDSSTGQKQPEGARSEEVCQEKRQNPNAECGNSLKRCSVLLNHHCVRSVKRLYKCSDCTKSFKWKSHLTCHQRIHTDERPFKCPDCPKCFKTNSHLTGHQRIHKGEKPIKYCECGKGFKYSSILQRHQRIHTGERPFKCPECPKSFKNSFHLTCHQRIHTGERPFKCCECGKHFKYSFVLKRHQRMHTAVGPFKCSECGKGFKFGYELQHHNRIHTEKRPFKCPECSKSFKSKSQLTYHQRTHTGERPFKCRECEMSFKYSFVLKRHQRIHTGERSIKCVARVYGVLRPGSVTDGAGGPTDPRPRKGIMGKGKRGKGKREKGRKTGLTSKQWQ", "length": 492, "header": "tr|A0A8V0XJS1-1|A0A3Q2TVZ6_CHICK Computationally mapped isoform of MHCY region zinc finger protein 2 OS=Gallus gallus OX=9031 GN=ZNFY2 PE=3 SV=1 CANONICAL=A0A3Q2TVZ6-1" }, "locus": { "chromosome": "16", "start_pos": 1672069, "end_pos": 1669731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008532.1", "url": "https://www.ensembl.org/id/ENSGALT00010008532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004992.1", "url": "https://www.ensembl.org/id/ENSGALP00010004992.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-GGA-9843940", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843940", "resource": "Reactome", "description": "Regulation of endogenous retroelements by KRAB-ZFP proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TVZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TVZ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 534, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TVZ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TVZ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 501 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TW24-1", "uniprot_ac": "A0A3Q2TW24", "uniprot_id": "A0A3Q2TW24_CHICK", "mass": { "chemical_mass": 53356.0, "monoisotopic_mass": 53356.0 }, "refseq": { "ac": "XP_046755273", "name": "myocardial zonula adherens protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755273" }, "gene_names": [ { "name": "MYZAP", "type": "recommended", "evidence": [ { "id": "A0A3Q2TW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ] }, { "name": "MYZAP", "type": "synonym", "evidence": [ { "id": "XP_046755273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755273" } ] } ], "protein_names": [ { "name": "Myocardial zonula adherens protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2TW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24/entry#names_and_taxonomy" } ] }, { "name": "myocardial zonula adherens protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046755273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755273" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755273" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYZAP", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24", "locus": { "chromosome": "10", "start_pos": 7273583, "end_pos": 7332471, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023113", "url": "https://www.ensembl.org/id/ENSGALG00010023113" } ] } } ], "crossref": [ { "id": "A0A3Q2TW24", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TW24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036680", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036680", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415404", "url": "https://www.ncbi.nlm.nih.gov/gene/415404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW24", "url": "https://www.orthodb.org/?gene=A0A3Q2TW24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL68", "url": "https://www.orthodb.org/?gene=A0A8V0ZL68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZUH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_046755273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW24-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKFVKMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEVRATLEKVRKKMYGEYDEMKRKIQQLTNELKVTNAHQESLENHVRVQAAALDSFSEMNSSLTSASIDLQKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLEETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEIEMLRKKVKEKELFIIQLLEKISFLECENKELQDKLEYLMENQPKTNVETRDAGVGCDLPSSTSNDNGRSPESTRPMRTYTPFKRVLEYSTKNSTS", "length": 454, "header": "tr|A0A3Q2TW24-1|A0A3Q2TW24_CHICK Isoform 1 of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TW24-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24/entry", "sequence": { "sequence": "MRKFVKMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEVRATLEKVRKKMYGEYDEMKRKIQQLTNELKVTNAHQESLENHVRVQAAALDSFSEMNSSLTSASIDLQKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLEETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEIEMLRKKVKEKELFIIQLLEKISFLECENKELQDKLEYLMENQPKTNVETRDAGVGCDLPSSTSNDNGRSPESTRPMRTYTPFKRVLEYSTKNSTS", "length": 454, "header": "tr|A0A3Q2TW24-1|A0A3Q2TW24_CHICK Isoform 1 of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "locus": { "chromosome": "10", "start_pos": 7321813, "end_pos": 7277087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056340.1", "url": "https://www.ensembl.org/id/ENSGALT00010056340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034108.1", "url": "https://www.ensembl.org/id/ENSGALP00010034108.1" } ] } }, { "isoform_ac": "A0A8V0ZL68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL68/entry", "sequence": { "sequence": "MFCKRSGSVLSATHLRLKVFLCWLCKNQQTLWSAFAAEMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEVRATLEKVRKKMYGEYDEMKRKIQQLTNELKVTNAHQESLENHVRVQAAALDSFSEMNSSLTSASIDLQKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLEETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEIEMLRKKVKEKELFIIQLLEKISFLECENKELQDKLEYLMENQPKTNVETRDAGVGCDLPSSTSNDNGRSPESTRPMRTYTPFKRVLEYSTKNSTS", "length": 486, "header": "tr|A0A8V0ZL68-1|A0A8V0ZL68_CHICK Computationally mapped isoform of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "locus": { "chromosome": "10", "start_pos": 7332397, "end_pos": 7277087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056343.1", "url": "https://www.ensembl.org/id/ENSGALT00010056343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034110.1", "url": "https://www.ensembl.org/id/ENSGALP00010034110.1" } ] } }, { "isoform_ac": "A0A8V0ZRH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH1/entry", "sequence": { "sequence": "MLRYSSGLTVTATTPRRTAGDGGRARRKMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLEETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEIEMLRKKVKEKELFIIQLLEKISFLECENKELQDKLEYLMENQPKTNVETRDAGVGCDLPSSTSNDNGRSPESTRPMRTYTPFKRVLEYSTKNSTS", "length": 407, "header": "tr|A0A8V0ZRH1-1|A0A8V0ZRH1_CHICK Computationally mapped isoform of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "locus": { "chromosome": "10", "start_pos": 7317902, "end_pos": 7277087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056339.1", "url": "https://www.ensembl.org/id/ENSGALT00010056339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034107.1", "url": "https://www.ensembl.org/id/ENSGALP00010034107.1" } ] } }, { "isoform_ac": "A0A8V0ZTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTF6/entry", "sequence": { "sequence": "MRKFVKMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEVRATLEKVRKKMYGEYDEMKRKIQQLTNELKVTNAHQESLENHVRVQAAALDSFSEMNSSLTSASIDLQKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLEETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEVMAHELFSSFSLRFVG", "length": 374, "header": "tr|A0A8V0ZTF6-1|A0A3Q2TW24_CHICK Computationally mapped isoform of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "locus": { "chromosome": "10", "start_pos": 7321813, "end_pos": 7284736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056329.1", "url": "https://www.ensembl.org/id/ENSGALT00010056329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034099.1", "url": "https://www.ensembl.org/id/ENSGALP00010034099.1" } ] } }, { "isoform_ac": "A0A8V0ZUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUH4/entry", "sequence": { "sequence": "MLRYSSGLTVTATTPRRTAGDGGRARRKMNVCRLRLTVPPDEVSQPEQGAKEPERKKQELYHVPNGMSPGKLSHGMVYGVVHRTDNNHKREMVVYGWSADQLKEEMNYIKEVRATLEKVRKKMYGEYDEMKRKIQQLTNELKVTNAHQESLENHVRVQAAALDSFSEMNSSLTSASIDLQKTLVDVTLENTDIREQIRNLKHTHEQSMEKLREKQKQLETAQIENQLLKLKVESSQEANAEVMREMTRKLYNQYEEKMREEEQKHKAEKEILLETNRLLKAIEESNKKMQITETSIKEKDQRIGELDRLIERMEEERHQLQKQLELNEIQLSGAKSESNSDSERSQHLEEVAASLRERIKHLDDMVHCQQKKVKHMVEEIEMLRKKVKEKELFIIQLLEKISFLECENKELQDKLEYLMENQPKTNVETRDAGVGCDLPSSTSNDNGRSPESTRPMRTYTPFKRVLEYSTKNSTS", "length": 475, "header": "tr|A0A8V0ZUH4-1|A0A3Q2TW24_CHICK Computationally mapped isoform of Myocardial zonula adherens protein OS=Gallus gallus OX=9031 GN=MYZAP PE=4 SV=1 CANONICAL=A0A3Q2TW24-1" }, "locus": { "chromosome": "10", "start_pos": 7317902, "end_pos": 7277087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056335.1", "url": "https://www.ensembl.org/id/ENSGALT00010056335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034103.1", "url": "https://www.ensembl.org/id/ENSGALP00010034103.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 451, "end_pos": 453 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TWA0-1", "uniprot_ac": "A0A3Q2TWA0", "uniprot_id": "A0A3Q2TWA0_CHICK", "mass": { "chemical_mass": 9648.0, "monoisotopic_mass": 9648.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Inhibitor of growth protein N-terminal histone-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q2TWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0", "locus": {} } ], "crossref": [ { "id": "A0A3Q2TWA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000050398", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000050398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10333:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10333:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TWA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYLDMIKQRPMNLHDRFTKMHGMDLHMQNAMDQLEQSVNDFLMNIKKNKPELREEQMTSIKNNYYKTLEDADEKVQLAN", "length": 80, "header": "tr|A0A3Q2TWA0-1|A0A3Q2TWA0_CHICK Isoform 1 of Inhibitor of growth protein N-terminal histone-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2TWA0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0/entry", "sequence": { "sequence": "MLYLDMIKQRPMNLHDRFTKMHGMDLHMQNAMDQLEQSVNDFLMNIKKNKPELREEQMTSIKNNYYKTLEDADEKVQLAN", "length": 80, "header": "tr|A0A3Q2TWA0-1|A0A3Q2TWA0_CHICK Isoform 1 of Inhibitor of growth protein N-terminal histone-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2TWA0-1" }, "locus": { "chromosome": "1", "start_pos": 84433419, "end_pos": 84433180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015969.1", "url": "https://www.ensembl.org/id/ENSGALT00010015969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009204.1", "url": "https://www.ensembl.org/id/ENSGALP00010009204.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TWA0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 80, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TWA0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TWA0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA0" }, { "id": "PF12998", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Inhibitor of growth protein N-terminal histone-binding", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 80, "start_aa": "Tyr", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UFR3-1", "uniprot_ac": "A0A3Q2UFR3", "uniprot_id": "A0A3Q2UFR3_CHICK", "mass": { "chemical_mass": 153392.0, "monoisotopic_mass": 153392.0 }, "refseq": { "ac": "XP_421777", "name": "attractin-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421777" }, "gene_names": [ { "name": "ATRNL1", "type": "recommended", "evidence": [ { "id": "A0A3Q2UFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3" } ] }, { "name": "ATRNL1", "type": "synonym", "evidence": [ { "id": "XP_421777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421777" } ] } ], "protein_names": [ { "name": "Attractin like 1", "type": "synonym", "evidence": [ { "id": "A0A3Q2UFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3/entry#names_and_taxonomy" } ] }, { "name": "attractin-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421777" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_421777.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421777" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATRNL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3", "locus": { "chromosome": "6", "start_pos": 29345214, "end_pos": 28927754, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022603", "url": "https://www.ensembl.org/id/ENSGALG00010022603" } ] } } ], "crossref": [ { "id": "ENSGALG00000009152", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009152", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03597", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03597", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423915", "url": "https://www.ncbi.nlm.nih.gov/gene/423915", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423915", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423915", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSMSVRN", "url": "https://omabrowser.org/oma/group/CSMSVRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TWA8", "url": "https://www.orthodb.org/?gene=A0A3Q2TWA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UFR3", "url": "https://www.orthodb.org/?gene=A0A3Q2UFR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP54", "url": "https://www.orthodb.org/?gene=A0A8V0ZP54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR12", "url": "https://www.orthodb.org/?gene=A0A8V0ZR12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR22", "url": "https://www.orthodb.org/?gene=A0A8V0ZR22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZWM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZWM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYK5", "url": "https://www.orthodb.org/?gene=E1BYK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421777", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWA8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYK5", "url": "https://www.uniprot.org/uniprotkb/E1BYK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BYK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCSGNKAAVLTVFLCLPRGSSGVPPPGQSGLAIASALIDISQQKPTECKDKSSGVRNRKHHLSTRQGTCV", "length": 1383, "header": "tr|A0A3Q2UFR3-1|A0A3Q2UFR3_CHICK Isoform 1 of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TWA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWA8/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSNLCGSDSRWPAAPLLLSM", "length": 1260, "header": "tr|A0A3Q2TWA8-1|A0A3Q2UFR3_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29232347, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055014.1", "url": "https://www.ensembl.org/id/ENSGALT00010055014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033262.1", "url": "https://www.ensembl.org/id/ENSGALP00010033262.1" } ] } }, { "isoform_ac": "A0A3Q2UFR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCSGNKAAVLTVFLCLPRGSSGVPPPGQSGLAIASALIDISQQKPTECKDKSSGVRNRKHHLSTRQGTCV", "length": 1383, "header": "tr|A0A3Q2UFR3-1|A0A3Q2UFR3_CHICK Isoform 1 of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29344210, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055067.1", "url": "https://www.ensembl.org/id/ENSGALT00010055067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033297.1", "url": "https://www.ensembl.org/id/ENSGALP00010033297.1" } ] } }, { "isoform_ac": "A0A8V0ZP54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP54/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRRE", "length": 1268, "header": "tr|A0A8V0ZP54-1|A0A8V0ZP54_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29151495, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055007.1", "url": "https://www.ensembl.org/id/ENSGALT00010055007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033258.1", "url": "https://www.ensembl.org/id/ENSGALP00010033258.1" } ] } }, { "isoform_ac": "A0A8V0ZR12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR12/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCSGNKAAVLTVFLCLPRGSSGVPPPGQSDYQ", "length": 1345, "header": "tr|A0A8V0ZR12-1|A0A8V0ZR12_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29333860, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055036.1", "url": "https://www.ensembl.org/id/ENSGALT00010055036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033275.1", "url": "https://www.ensembl.org/id/ENSGALP00010033275.1" } ] } }, { "isoform_ac": "A0A8V0ZR22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR22/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQLFLILTAGSCRRLENQTNLLGFSTERGCSQTNCHRAVFRKQSCRPHSISVSAKRIIRSPTPGSVRSCNCKCTDRHFTTEAYGV", "length": 1304, "header": "tr|A0A8V0ZR22-1|A0A8V0ZR22_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29344143, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055049.1", "url": "https://www.ensembl.org/id/ENSGALT00010055049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033285.1", "url": "https://www.ensembl.org/id/ENSGALP00010033285.1" } ] } }, { "isoform_ac": "A0A8V0ZRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ6/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLELLCFL", "length": 1309, "header": "tr|A0A8V0ZRQ6-1|A0A8V0ZRQ6_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29236566, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055020.1", "url": "https://www.ensembl.org/id/ENSGALT00010055020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033264.1", "url": "https://www.ensembl.org/id/ENSGALP00010033264.1" } ] } }, { "isoform_ac": "A0A8V0ZRS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS3/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLEVLQLQVH", "length": 1311, "header": "tr|A0A8V0ZRS3-1|A0A8V0ZRS3_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29344109, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055042.1", "url": "https://www.ensembl.org/id/ENSGALT00010055042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033279.1", "url": "https://www.ensembl.org/id/ENSGALP00010033279.1" } ] } }, { "isoform_ac": "A0A8V0ZWM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM2/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLMRERQQMASRPFASVDVALEVGAEQTDFLRGPLEDRPQGPNNAPKEIHLDEDD", "length": 1323, "header": "tr|A0A8V0ZWM2-1|A0A3Q2UFR3_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29260453, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055023.1", "url": "https://www.ensembl.org/id/ENSGALT00010055023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033267.1", "url": "https://www.ensembl.org/id/ENSGALP00010033267.1" } ] } }, { "isoform_ac": "A0A8V0ZWM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWM7/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREDRPQGPNNAPKEIHLDEDD", "length": 1287, "header": "tr|A0A8V0ZWM7-1|A0A3Q2UFR3_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=1 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29260453, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055031.1", "url": "https://www.ensembl.org/id/ENSGALT00010055031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033272.1", "url": "https://www.ensembl.org/id/ENSGALP00010033272.1" } ] } }, { "isoform_ac": "E1BYK5-1", "url": "https://www.uniprot.org/uniprotkb/E1BYK5/entry", "sequence": { "sequence": "MAPAGSAEPGSALSRAGAAPPPLGAWRPFPSACCCCFSALLDVNSWLLFYGFLYLALYAQVSQSKSCDKISCFSGHCVNSTCVCDQGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAILRLRFNHFATECSWDHMYVYDGDSIYAPLIAVFSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSEHGKCTTSLSIPSRVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVVPVSKGPLQRYGHTLALYQEDIYMYGGKIETNNGNVTDELWIFNIHSQAWSIRTPAVLVHGQQYAVEGHSAHIVELDSRDVVMIIIFGYSAIYGYTSIVQEYYIRSNSWLVPETKGAIVQGGYGHTSVYDELTKSVYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHTAVVSNGSMYIFGGFSSVLLNDILVYKPPNCEAFRDEELCKNARPGIRCLWNKKHCESWESGNANNILRAKCPKKTAAADDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLHLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTLQKISPWVGLRKINISYWGWDDMSPFTNTTLQWLPGEPNDSGFCAYLERAEVAGLKANPCTAMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGKGQCLEGSSRGPMKPVGMHSAEMVLDATLCPKEKSYEWSFIQCPACQCNGHSTCINSNVCDQCKNLTTGKQCETCMPGYYGDPTNGGQCTACTCSGHANICHMQTGKCFCTTKGIKGDQCQLCDSENRYLGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSIGSTAGTISGEEIPVVSKANIKEYRDSFSCEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREGAPKPIAIEPCSGNKAAVLTVFLCLPRGSSGVPPPGQSGLAIASALIDISQQKPTECKDKSSGVRNRKHHLSTRQGTCV", "length": 1347, "header": "tr|E1BYK5-1|A0A3Q2UFR3_CHICK Computationally mapped isoform of Attractin like 1 OS=Gallus gallus OX=9031 GN=ATRNL1 PE=4 SV=4 CANONICAL=A0A3Q2UFR3-1" }, "locus": { "chromosome": "6", "start_pos": 29344210, "end_pos": 28927953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055073.1", "url": "https://www.ensembl.org/id/ENSGALT00010055073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033301.1", "url": "https://www.ensembl.org/id/ENSGALP00010033301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423915", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NAU7-1", "protein_name": "Attractin like 1", "gene_name": "ATRNL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPGGRARTGPPQPAAPGPWRARPAGGGGGGGASSWLLDGNSWLLCYGLIYLALYAQVSQSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVSNQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGAVSRGPLQRYGHSLALYQENIFMYGGRIETSDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYGLVDDLYKYEVNPKTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCIWNKNHCESWDSGNTNNILRAKCPLKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISSTSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWIHVGDACLRINSSRENYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTRRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLVGMLNNEMLLDTSLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHMHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETPIVSKTNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEHTDFLRGSLEGAPKPIAIEPCAGNRAAVLTVFLCLPRGPSGAPPPGQSGLAIASALIDISQQKPSDSKDKTSGVRNRKHHLSTRQGTCV", "length": 1381 }, "evidence": [ { "id": "A0A3Q2UFR3", "url": "https://omabrowser.org/oma/group/A0A3Q2UFR3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I5Y1Z3-1", "protein_name": "Attractin-like protein 1", "gene_name": "Atrnl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPGVGARSGAPQPAAPVLWRARPAGGGGASSWLLLDGNSWLLCYGFLYLALYAQVSQSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLVAVLSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVASQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGAVSRGPLQRYGHSLALYQENIFMYGGRMETSDGNVTDELWVFNVRSQSWSTKTPTILGHGQQYAVEGHSAHIMELDSGDVVMIVIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEMTKSVYVHGGYKALPGNKYGLVDDLYKYEVNSRTWTILKESGFARYLHSAVLISGAVLVFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKTLPKPNLHRDVNRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPSCKAFRDEELCRNAGPGIKCVWNKNHCESWESGNANLLRAKCPPRTAASDDRCYRYADCASCTANTNGCQWCDDKKCISASSNCSTSVRNYTKCHIRNEQICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWNHVGDSCLRINSSRESYDSAKLYCYNLSGNLASLTTSKEVGFVLDEIQKNTQQRVSPWVGLRKINISYWGWEDMSPFTNTSLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCSLRTSCANCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGYCIEGSSRGPMKLAGVHNSEVALDTSLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGRQCQDCMPGYYGDPTNGGQCTACTCGGHANVCHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTGGTISGEETPIVSKMNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCAGNRAAVLTVFLCLPRGTSGAPPPGQSGLAIASALIDISQQKPSDNKDKTSGVRNRKHLSTRQGTCV", "length": 1377 }, "evidence": [ { "id": "A0A3Q2UFR3", "url": "https://omabrowser.org/oma/group/A0A3Q2UFR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VV63-1", "protein_name": "Attractin-like protein 1", "gene_name": "ATRNL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGGRARTGTPQPAAPGVWRARPAGGGGGGASSWLLDGNSWLLCYGFLYLALYAQVSQSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSKNNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGPLEGAPKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSKDKTSGVRNRKHLSTRQGTCV", "length": 1379 }, "evidence": [ { "id": "A0A3Q2UFR3", "url": "https://omabrowser.org/oma/group/A0A3Q2UFR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6A051-1", "protein_name": "Attractin-like protein 1", "gene_name": "Atrnl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGVRARSGAPQPASPVLWRARPAGGGGASSWLLLDGNSWLLCYGFLYLALYAQVSQSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLVAVLSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVASQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGAVSRGPLQRYGHSLALYQENIFMYGGRMETSDGNVTDELWVFNVRSQSWSTKTPTVLGHSQQYAVEGHSAHIMELDSRDVVMIVIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEVTKSIYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKTLPKPNLHRDVNRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPNCKAFRDEELCRNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKTAATDDRCYRYADCASCTANTNGCQWCDDKKCISASSNCSTSVRNYTKCHIRNEQICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWNHVGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKFTQQKVSPWVGLRKINISYWGWEDMSPFTNTSLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCSLRTSCANCTSSGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGYCIEGSSRGPMKLAGVHNSDVVLDTSLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGRQCQECMPGYYGDPTNGGQCTACTCGGHANVCHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTGGTISGEETPIVSKTNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKPSDNKDKTSGVRNRKHLSTRQGTCV", "length": 1378 }, "evidence": [ { "id": "A0A3Q2UFR3", "url": "https://omabrowser.org/oma/group/A0A3Q2UFR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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}, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 707, "end_pos": 709 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 834, "end_pos": 836 }, { "start_pos": 845, "end_pos": 847 }, { "start_pos": 901, "end_pos": 903 }, { "start_pos": 945, "end_pos": 947 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"type": "synonym", "evidence": [ { "id": "NP_001384290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ] }, { "name": "NTN3", "type": "synonym", "evidence": [ { "id": "NP_001384290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ] }, { "name": "netrin-3", "type": "synonym", "evidence": [ { "id": "NP_001384290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ] } ], "protein_names": [ { "name": "Netrin 1", "type": "synonym", "evidence": [ { "id": "A0A3Q2TWG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9/entry#names_and_taxonomy" } ] }, { "name": "netrin 3", "type": "synonym", "evidence": [ { "id": "NP_001384290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ] }, { "name": "netrin-2", "type": "synonym", "evidence": [ { "id": "NP_001384290", "database": "RefSeq", "url": 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The reference sequence was derived from CD216115.1, JAENSK010000257.1 and L34550.1. On Nov 9, 2021 this sequence version replaced XP_040503256.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ] }, { "annotation": "In embryonic stem cell cultures Netrin-1 promoted neurite outgrowth.", "evidence": [ { "database": "RefSeq", "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" }, { "database": "PubMed", "id": "16840550", "url": "https://glygen.org/publication/PubMed/16840550" } ] }, { "annotation": "Netrin-1 plays an important role in promoting blood vessel formation in the central nervous system, and could have broad implication in cerebrovascular development and remodeling", "evidence": [ { "database": "RefSeq", "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" }, { "database": "PubMed", "id": "18461079", "url": "https://glygen.org/publication/PubMed/18461079" } ] } ], "disease": [], "snv": [], 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03579", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03579", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396387", "url": "https://www.ncbi.nlm.nih.gov/gene/396387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TWG9", "url": "https://www.orthodb.org/?gene=A0A3Q2TWG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z305", "url": "https://www.orthodb.org/?gene=A0A8V0Z305", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8R1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8R6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TWG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z305", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z305", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z305-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z305-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPQLLRLLLTTSVLRLAQTANPFVAQQTPPDPCYDESGAPRRCIPEFVNAAFGKEVQASSTCGKPPTRHCDASDPRRAHPPAYLTDLNTAANMTCWRSETLHHLPHNVTLTLSLGKKFEVVYVSLQFCSPRPESTAIFKSMDYGKTWVPYQYYSSQCRKIYGKPSKATVTKQNEQEALCTDGLTDLYPLTGGLIAFSTLDGRPSAQDFDSSPVLQDWVTATDIRVVFSRPHLFRELGGREAGEEDGGAGATPYYYSVGELQVGGRCKCNGHASRCVKDKEQKLVCDCKHNTEGPECDRCKPFHYDRPWQRASAREANECLACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKSITDRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAKGFQQSRSPVAPCIKIPAINPTSLVTSTEAPADCDSYCKPAKGNYKINMKKYCKKDYVVQVNILEMETVANWAKFTINILSVYKCRDERVKRGDNFLWIHLKDLSCKCPKIQISKKYLVMGISENSTDRPGLMADKNSLVIQWRDAWTRRLRKLQRREKKGKCVKP", "length": 587, "header": "tr|A0A3Q2TWG9-1|A0A3Q2TWG9_CHICK Isoform 1 of Netrin 1 OS=Gallus gallus OX=9031 GN=NTN3 PE=4 SV=1 CANONICAL=A0A3Q2TWG9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TWG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9/entry", "sequence": { "sequence": "MEAPQLLRLLLTTSVLRLAQTANPFVAQQTPPDPCYDESGAPRRCIPEFVNAAFGKEVQASSTCGKPPTRHCDASDPRRAHPPAYLTDLNTAANMTCWRSETLHHLPHNVTLTLSLGKKFEVVYVSLQFCSPRPESTAIFKSMDYGKTWVPYQYYSSQCRKIYGKPSKATVTKQNEQEALCTDGLTDLYPLTGGLIAFSTLDGRPSAQDFDSSPVLQDWVTATDIRVVFSRPHLFRELGGREAGEEDGGAGATPYYYSVGELQVGGRCKCNGHASRCVKDKEQKLVCDCKHNTEGPECDRCKPFHYDRPWQRASAREANECLACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKSITDRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAKGFQQSRSPVAPCIKIPAINPTSLVTSTEAPADCDSYCKPAKGNYKINMKKYCKKDYVVQVNILEMETVANWAKFTINILSVYKCRDERVKRGDNFLWIHLKDLSCKCPKIQISKKYLVMGISENSTDRPGLMADKNSLVIQWRDAWTRRLRKLQRREKKGKCVKP", "length": 587, "header": "tr|A0A3Q2TWG9-1|A0A3Q2TWG9_CHICK Isoform 1 of Netrin 1 OS=Gallus gallus OX=9031 GN=NTN3 PE=4 SV=1 CANONICAL=A0A3Q2TWG9-1" }, "locus": { "chromosome": "14", "start_pos": 14032994, "end_pos": 14014936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042344.1", "url": "https://www.ensembl.org/id/ENSGALT00010042344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024834.1", "url": "https://www.ensembl.org/id/ENSGALP00010024834.1" } ] } }, { "isoform_ac": "A0A8V0Z305-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z305/entry", "sequence": { "sequence": "MRAGAWRRWCSGRAAPAPRYRRALPQCPLRSSRSLQRHPRVGRGGRMEAPQLLRLLLTTSVLRLAQTANPFVAQQTPPDPCYDESGAPRRCIPEFVNAAFGKEVQASSTCGKPPTRHCDASDPRRAHPPAYLTDLNTAANMTCWRSETLHHLPHNVTLTLSLGKKFEVVYVSLQFCSPRPESTAIFKSMDYGKTWVPYQYYSSQCRKIYGKPSKATVTKQNEQEALCTDGLTDLYPLTGGLIAFSTLDGRPSAQDFDSSPVLQDWVTATDIRVVFSRPHLFRELGGREAGEEDGGAGATPYYYSVGELQVGGRCKCNGHASRCVKDKEQKLVCDCKHNTEGPECDRCKPFHYDRPWQRASAREANECLACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKSITDRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAKGFQQSRSPVAPCIKIPAINPTSLVTSTEAPADCDSYCKPAKGNYKINMKKYCKKDYVVQVNILEMETVANWAKFTINILSVYKCRDERVKRGDNFLWIHLKDLSCKCPKIQISKKYLVMGISENSTDRPGLMADKNSLVIQWRDAWTRRLRKLQRREKKGKCVKP", "length": 633, "header": "tr|A0A8V0Z305-1|A0A8V0Z305_CHICK Computationally mapped isoform of Netrin 1 OS=Gallus gallus OX=9031 GN=NTN3 PE=4 SV=1 CANONICAL=A0A3Q2TWG9-1" }, "locus": { "chromosome": "14", "start_pos": 14041724, "end_pos": 14014936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042350.1", "url": "https://www.ensembl.org/id/ENSGALT00010042350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024840.1", "url": "https://www.ensembl.org/id/ENSGALP00010024840.1" } ] } }, { "isoform_ac": "A0A8V0Z8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R1/entry", "sequence": { "sequence": "MGRAPLCASPRAPASPRHGCCSPAHCGCPASSSDAMCTEAGRMEAPQLLRLLLTTSVLRLAQTANPFVAQQTPPDPCYDESGAPRRCIPEFVNAAFGKEVQASSTCGKPPTRHCDASDPRRAHPPAYLTDLNTAANMTCWRSETLHHLPHNVTLTLSLGKKFEVVYVSLQFCSPRPESTAIFKSMDYGKTWVPYQYYSSQCRKIYGKPSKATVTKQNEQEALCTDGLTDLYPLTGGLIAFSTLDGRPSAQDFDSSPVLQDWVTATDIRVVFSRPHLFRELGGREAGEEDGGAGATPYYYSVGELQVGGRCKCNGHASRCVKDKEQKLVCDCKHNTEGPECDRCKPFHYDRPWQRASAREANECLACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKSITDRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAKGFQQSRSPVAPCIKIPAINPTSLVTSTEAPADCDSYCKPAKGNYKINMKKYCKKDYVVQVNILEMETVANWAKFTINILSVYKCRDERVKRGDNFLWIHLKDLSCKCPKIQISKKYLVMGISENSTDRPGLMADKNSLVIQWRDAWTRRLRKLQRREKKGKCVKP", "length": 629, "header": "tr|A0A8V0Z8R1-1|A0A8V0Z8R1_CHICK Computationally mapped isoform of Netrin 1 OS=Gallus gallus OX=9031 GN=NTN3 PE=4 SV=1 CANONICAL=A0A3Q2TWG9-1" }, "locus": { "chromosome": "14", "start_pos": 14034461, "end_pos": 14014936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042332.1", "url": "https://www.ensembl.org/id/ENSGALT00010042332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024823.1", "url": "https://www.ensembl.org/id/ENSGALP00010024823.1" } ] } }, { "isoform_ac": "A0A8V0Z8R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R6/entry", "sequence": { "sequence": "MEQCGSCWAALVCVFSSGRMEAPQLLRLLLTTSVLRLAQTANPFVAQQTPPDPCYDESGAPRRCIPEFVNAAFGKEVQASSTCGKPPTRHCDASDPRRAHPPAYLTDLNTAANMTCWRSETLHHLPHNVTLTLSLGKKFEVVYVSLQFCSPRPESTAIFKSMDYGKTWVPYQYYSSQCRKIYGKPSKATVTKQNEQEALCTDGLTDLYPLTGGLIAFSTLDGRPSAQDFDSSPVLQDWVTATDIRVVFSRPHLFRELGGREAGEEDGGAGATPYYYSVGELQVGGRCKCNGHASRCVKDKEQKLVCDCKHNTEGPECDRCKPFHYDRPWQRASAREANECLACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKSITDRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAKGFQQSRSPVAPCIKIPAINPTSLVTSTEAPADCDSYCKPAKGNYKINMKKYCKKDYVVQVNILEMETVANWAKFTINILSVYKCRDERVKRGDNFLWIHLKDLSCKCPKIQISKKYLVMGISENSTDRPGLMADKNSLVIQWRDAWTRRLRKLQRREKKGKCVKP", "length": 606, "header": "tr|A0A8V0Z8R6-1|A0A8V0Z8R6_CHICK Computationally mapped isoform of Netrin 1 OS=Gallus gallus OX=9031 GN=NTN3 PE=4 SV=1 CANONICAL=A0A3Q2TWG9-1" }, "locus": { "chromosome": "14", "start_pos": 14039300, "end_pos": 14014936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042338.1", "url": "https://www.ensembl.org/id/ENSGALT00010042338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024828.1", "url": "https://www.ensembl.org/id/ENSGALP00010024828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.", "journal": "Stem cells (Dayton, Ohio)", "date": "2006", "authors": "Lin L, Isacson O", "evidence": [ { "database": "RefSeq", "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ], "reference": [ { "type": "PubMed", "id": "16840550", "url": "https://glygen.org/publication/PubMed/16840550" } ] }, { "title": "Overexpression of netrin-1 induces neovascularization in the adult mouse brain.", "journal": "Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism", "date": "2008-09", "authors": "Fan Yongfeng, Shen Fanxia, Chen Yongmei, Hao Qi, Liu Weizhong, Su Hua, Young William L, Yang Guo-Yuan", "evidence": [ { "database": "RefSeq", "id": "NP_001384290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384290" } ], "reference": [ { "type": "PubMed", "id": "18461079", "url": "https://glygen.org/publication/PubMed/18461079" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9" } ], "pmid": "" }, { "name": "basement membrane", "id": 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"url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TWG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSLKPSKPTFKSYLLPLPQAEDNITSEPRIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLVCTNFKISFITDDPMPLQKFHYKNLLLGEHDVPLTCIEQIVTVNDTKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDEAGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGEIYHNPAKKVNGVDPGGGGSGGISSTSGQQTPLFETYSDWDREIKRTGASEWRVCSVNEGYMISTCLPEYFVVPSSLADQDLKLYSHSFIGRRMPLWSWNHPNGSALVRMANIKDVLQQRRIDQRICNAITRSHPLRSDVYKSDLDKCLPNIQEIQAAHIKLKQLCVNEPFEETEEKWLSSLENTRWLEYIRSFLKHSAELVYMMECKHVSVVLQEEEGRDLSCLAASLVQVMLDPYFRTIVGFQSLIQKEWVMAGYQFLDRCNHLKRSDKESPLFLMFLDCVWQLLEQYPAAFEFSEVYLMILYDSARISLFGTFLFNCPHQRVKESTEFAISKNIQLGDEKGLRFPCVWDWSLQFTSRDRLLFHNPLYIGKSAPCVQNGAVKSFKRSKKNYSSTLRGVPPALKNGIISEQEFLPRRNSLILKLKPDFLQQTESQSNSMEQYFRDWFAKPVDLHGVILPHLSGTQIKLWKLCYFRWVPEAQINHGGFIAAFHKVSLLADEVDMLNRNLRQCKSNSPLQGSCSELDQGRMYFRANGLNDTSGAPDFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED", "length": 771, "header": "tr|A0A3Q2TXM8-1|A0A3Q2TXM8_CHICK Isoform 1 of Myotubularin-related protein 10 OS=Gallus gallus OX=9031 GN=MTMR10 PE=1 SV=1 CANONICAL=A0A3Q2TXM8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TXM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8/entry", "sequence": { "sequence": "MFSLKPSKPTFKSYLLPLPQAEDNITSEPRIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLVCTNFKISFITDDPMPLQKFHYKNLLLGEHDVPLTCIEQIVTVNDTKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDEAGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGEIYHNPAKKVNGVDPGGGGSGGISSTSGQQTPLFETYSDWDREIKRTGASEWRVCSVNEGYMISTCLPEYFVVPSSLADQDLKLYSHSFIGRRMPLWSWNHPNGSALVRMANIKDVLQQRRIDQRICNAITRSHPLRSDVYKSDLDKCLPNIQEIQAAHIKLKQLCVNEPFEETEEKWLSSLENTRWLEYIRSFLKHSAELVYMMECKHVSVVLQEEEGRDLSCLAASLVQVMLDPYFRTIVGFQSLIQKEWVMAGYQFLDRCNHLKRSDKESPLFLMFLDCVWQLLEQYPAAFEFSEVYLMILYDSARISLFGTFLFNCPHQRVKESTEFAISKNIQLGDEKGLRFPCVWDWSLQFTSRDRLLFHNPLYIGKSAPCVQNGAVKSFKRSKKNYSSTLRGVPPALKNGIISEQEFLPRRNSLILKLKPDFLQQTESQSNSMEQYFRDWFAKPVDLHGVILPHLSGTQIKLWKLCYFRWVPEAQINHGGFIAAFHKVSLLADEVDMLNRNLRQCKSNSPLQGSCSELDQGRMYFRANGLNDTSGAPDFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED", "length": 771, "header": "tr|A0A3Q2TXM8-1|A0A3Q2TXM8_CHICK Isoform 1 of Myotubularin-related protein 10 OS=Gallus gallus OX=9031 GN=MTMR10 PE=1 SV=1 CANONICAL=A0A3Q2TXM8-1" }, "locus": { "chromosome": "10", "start_pos": 5786797, "end_pos": 5754092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060418.1", "url": "https://www.ensembl.org/id/ENSGALT00010060418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037177.1", "url": "https://www.ensembl.org/id/ENSGALP00010037177.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415382", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TXM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TXM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2TXM8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 771, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2TXM8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TXM8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2TXM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXM8" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 656, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 720, "end_pos": 722 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2TYS4-1", "uniprot_ac": "A0A3Q2TYS4", "uniprot_id": "A0A3Q2TYS4_CHICK", "mass": { "chemical_mass": 46140.0, "monoisotopic_mass": 46140.0 }, "refseq": {}, "gene_names": [ { "name": "GCNT2", "type": "recommended", "evidence": [ { "id": "A0A3Q2TYS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4" } ] } ], "protein_names": [ { "name": "Glucosaminyl (N-acetyl) transferase 2 (I blood group)", "type": "synonym", "evidence": [ { "id": "A0A3Q2TYS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GCNT2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4", "locus": { "chromosome": "2", "start_pos": 62989249, "end_pos": 63004305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010871", "url": "https://www.ensembl.org/id/ENSGALG00010010871" } ] } } ], "crossref": [ { "id": "A0A3Q2TYS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2TYS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000048035", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000048035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428479", "url": "https://www.ncbi.nlm.nih.gov/gene/428479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KTPVFLW", "url": "https://omabrowser.org/oma/group/KTPVFLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TYS4", "url": "https://www.orthodb.org/?gene=A0A3Q2TYS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAM3", "url": "https://www.orthodb.org/?gene=A0A8V0YAM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297:SF183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297:SF183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TYS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLRYCFFAVLILSISLPFVFYAINIHAQKSLRRLKFSVSSTLLEDCKALIEDKVSFLKENALKTSFGKFNCTEYITQNHYITRVLSAEEAAFPLAYIITMHKEFETFERLFRAVYMPQNVYCIHVDGKAPAALKQAVRRLVDCFPNAFLASRTERVVYGGVSRLRADLHCMRDLLASAVPWHYLLNACGQDFPLKTNWEIIQHLKAYRGKNITPGVLPPAHVTARTKYVHREQLYSLFSFMLPMFVHKAPPPHNLTLYFGSAYIAVTRPFAEFVLQDPRAIDLLAWSEDTYSPDEHFWVTLNRIPGVPGSMPNASWEGGLKAVKWIDMEDIHGGCHGHYVRGICVYGTGDLKWLFNSTCMFANKFELRTYPLTVECLELRHRKRTLAQSEVQVEPNWYF", "length": 401, "header": "tr|A0A3Q2TYS4-1|A0A3Q2TYS4_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase 2 (I blood group) OS=Gallus gallus OX=9031 GN=GCNT2 PE=3 SV=1 CANONICAL=A0A3Q2TYS4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TYS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYS4/entry", "sequence": { "sequence": "MSVLRYCFFAVLILSISLPFVFYAINIHAQKSLRRLKFSVSSTLLEDCKALIEDKVSFLKENALKTSFGKFNCTEYITQNHYITRVLSAEEAAFPLAYIITMHKEFETFERLFRAVYMPQNVYCIHVDGKAPAALKQAVRRLVDCFPNAFLASRTERVVYGGVSRLRADLHCMRDLLASAVPWHYLLNACGQDFPLKTNWEIIQHLKAYRGKNITPGVLPPAHVTARTKYVHREQLYSLFSFMLPMFVHKAPPPHNLTLYFGSAYIAVTRPFAEFVLQDPRAIDLLAWSEDTYSPDEHFWVTLNRIPGVPGSMPNASWEGGLKAVKWIDMEDIHGGCHGHYVRGICVYGTGDLKWLFNSTCMFANKFELRTYPLTVECLELRHRKRTLAQSEVQVEPNWYF", "length": 401, "header": "tr|A0A3Q2TYS4-1|A0A3Q2TYS4_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase 2 (I blood group) OS=Gallus gallus OX=9031 GN=GCNT2 PE=3 SV=1 CANONICAL=A0A3Q2TYS4-1" }, "locus": { "chromosome": "2", "start_pos": 63000525, "end_pos": 62990219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026015.1", "url": "https://www.ensembl.org/id/ENSGALT00010026015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014665.1", "url": "https://www.ensembl.org/id/ENSGALP00010014665.1" } ] } }, { "isoform_ac": "A0A8V0YAM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM3/entry", "sequence": { "sequence": "MSVLRYCFFAVLILSISLPFVFYAINIHAQKSLRRLKFSVSSTLLEDCKALIEDKVSFLKENALKTSFGKFNCTEYITQNHYITRVLSAEEAAFPLAYIITMHKEFETFERLFRAVYMPQNVYCIHVDGKAPAALKQAVRRLVDCFPNAFLASRTERVVYGGVSRLRADLHCMRDLLASAVPWHYLLNACGQDFPLKTNWEIIQHLKAYRGKNITPGVLPPAHVTARTKYVHREQLYSLFSFMLPMFVRKAPPPHNLTLYFGSAYIAVTRPFAEFVLQDPRAIDLLAWSEDTYSPDEHFWVTLNRIPGVPGSMPNASWEGGLKAVKWIDMEDIHGGCHGHYVRGICVYGTGDLKWLFNSTCMFANKFELRTYPLTVECLELRHRKRTLAQSEVQVEPNWYF", "length": 401, "header": "tr|A0A8V0YAM3-1|A0A3Q2TYS4_CHICK Computationally mapped isoform of Glucosaminyl (N-acetyl) transferase 2 (I blood group) OS=Gallus gallus OX=9031 GN=GCNT2 PE=3 SV=1 CANONICAL=A0A3Q2TYS4-1" }, "locus": { "chromosome": "2", "start_pos": 63000525, "end_pos": 62990219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026012.1", "url": "https://www.ensembl.org/id/ENSGALT00010026012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014662.1", "url": "https://www.ensembl.org/id/ENSGALP00010014662.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BBU6-1", "protein_name": "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSLMRFLFIASVSCVIIFIVFYAFHFGGEQSFQRLNNSDPLMLSQVCTSSIKGKTPFLWRDRLTIYEKSSCKEYLTQSHYITVPLSKEEADFPLAYIMVIHHNFDTFARLFRAVYMPQNVYCVHVDEKATTEFKDAVEHLLSCFPNAFLASKTEPVVYGGISRLQADLNCIKDLAASAVPWKYAINTCGQDFPLKTNREIVQYLKGLKGKNITPGVLPPAHAIGRTRYVHREHLGKELSYVIRTTALKPPPPHNLTIYFGSAYVALSREFATFVLQDPRAVDLLHWSKDTFSPDEHFWVTLNRIPGVPGSMPNASWAGNLRAVKWIDMEDKHGGCHGHYVHGICIYGNGDLKWLMNSSSLFANKFELSTYPLTVECLELRLRERTLNQSEIEIQPSWYF", "length": 400 }, "evidence": [ { "id": "A0A3Q2TYS4", "url": "https://omabrowser.org/oma/group/A0A3Q2TYS4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1N1F3-1", "protein_name": "Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)", "gene_name": "GCNT2", 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936735" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TZC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM125", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZC3", "locus": { "chromosome": "8", "start_pos": 19348240, "end_pos": 19333028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022581", "url": "https://www.ensembl.org/id/ENSGALG00010022581" } ] } } ], "crossref": [ { "id": "ENSGALG00000053697", "url": 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"id": "PTHR31416:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31416:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPELADLSSPRTPADADHIQRNILEEHVELWWFQDPKKSILCYGMAVVLILACGIGGIILLYSTSSRSGEWRLAVGTTLCLLALLVLLKQLLSSAIQDMNCIRSRHQIELLKSGGFSDCLVLLLSALVLLVCGVVLTILSTTTMQLSPARPLASMFTSGVVLLATGSALLLCLLLYLLCTSCCQAAPHGLETGEIRVFTISGRLAANRRLPPTSSMANLI", "length": 220, "header": "tr|A0A3Q2TZC3-1|A0A3Q2TZC3_CHICK Isoform 1 of Transmembrane protein 125 OS=Gallus gallus OX=9031 GN=TMEM125 PE=4 SV=1 CANONICAL=A0A3Q2TZC3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TZC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZC3/entry", "sequence": { "sequence": "MPELADLSSPRTPADADHIQRNILEEHVELWWFQDPKKSILCYGMAVVLILACGIGGIILLYSTSSRSGEWRLAVGTTLCLLALLVLLKQLLSSAIQDMNCIRSRHQIELLKSGGFSDCLVLLLSALVLLVCGVVLTILSTTTMQLSPARPLASMFTSGVVLLATGSALLLCLLLYLLCTSCCQAAPHGLETGEIRVFTISGRLAANRRLPPTSSMANLI", "length": 220, "header": "tr|A0A3Q2TZC3-1|A0A3Q2TZC3_CHICK Isoform 1 of Transmembrane protein 125 OS=Gallus gallus OX=9031 GN=TMEM125 PE=4 SV=1 CANONICAL=A0A3Q2TZC3-1" }, "locus": { "chromosome": "8", "start_pos": 19338000, "end_pos": 19337341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054966.1", "url": "https://www.ensembl.org/id/ENSGALT00010054966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033234.1", "url": 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"tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEGEAQAPRGRGLPPDVLAEQVELWWSQQPRRSALCFAVAVGLVAGCGAGGVALLSSTSSRSGEWRLAVGTALCLLALLVLVKQLMSSAVQDMNCIRQPHHVALLRSGGGADALVVLLSGLVLLVTGLTLAGLAAAPAPARPLAAMLSVGITLAASGALLLLGLLLYQVAVSGHCPPARTAAPTTRSDRSGNGSVFSISGQLSAGQRHETTSSIASLI", "length": 219 }, "evidence": [ { "id": "A0A3Q2TZC3", "url": "https://omabrowser.org/oma/group/A0A3Q2TZC3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CHQ6-1", "protein_name": "Transmembrane protein 125", "gene_name": "Tmem125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQQASVGRGLPPDVLAEQVELWWSQQPRRSLLCFSVAVILVAGCGAGGVALLSSTSSRSGEWRLAVGTVLCLLALLVLVKQLMSSAVQDMNCIRQAQHVALLRSGGGADAVVVLLSGFVLLVTGLTLAGLAAAPAPARPLAAMLSVGITLASLGSVLLLGLLLYQVGVSGHCPPICTEAFSAQNGHGDNSSIFSISGQLSSGQRHETTSSIASLI", "length": 216 }, "evidence": [ { "id": "A0A3Q2TZC3", "url": "https://omabrowser.org/oma/group/A0A3Q2TZC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AQ2-1", "protein_name": "Transmembrane protein 125", "gene_name": "TMEM125", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEQEAQAPGGRGLPPDMLAEQVELWWSQQPRRSALCFVVAVGLVAGCGAGGVALLSTTSSRSGEWRLATGTVLCLLALLVLVKQLMSSAVQDMNCIRQAHHVALLRSGGGADALVVLLSGLVLLVTGLTLAGLAAAPAPARPLAAMLSVGIALAALGSLLLLGLLLYQVGVSGHCPSICMATPSTHSGHGGHGSIFSISGQLSAGRRHETTSSIASLI", "length": 219 }, "evidence": [ { "id": "A0A3Q2TZC3", "url": "https://omabrowser.org/oma/group/A0A3Q2TZC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U045-1", "uniprot_ac": "A0A3Q2U045", "uniprot_id": "A0A3Q2U045_CHICK", "mass": { "chemical_mass": 8438.0, "monoisotopic_mass": 8438.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CEBPZ opposite strand", "type": "synonym", "evidence": [ { "id": "A0A3Q2U045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U045", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U045", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U045", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000052063", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000052063", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR037764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR38001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38001:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38001:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U045", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U045-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRRLVAGLVALEVAGLGGALLLYRAMDRSQDFRYTMQKRFPSVLEVYYKSNEWSGVHGIRENDQMAWLSSKN", "length": 73, "header": "tr|A0A3Q2U045-1|A0A3Q2U045_CHICK Isoform 1 of CEBPZ opposite strand OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U045-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U045-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U045/entry", "sequence": { "sequence": "MRRRLVAGLVALEVAGLGGALLLYRAMDRSQDFRYTMQKRFPSVLEVYYKSNEWSGVHGIRENDQMAWLSSKN", "length": 73, "header": "tr|A0A3Q2U045-1|A0A3Q2U045_CHICK Isoform 1 of CEBPZ opposite strand OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U045-1" }, "locus": { "chromosome": "3", "start_pos": 33195898, "end_pos": 33194272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016693.1", "url": "https://www.ensembl.org/id/ENSGALT00010016693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009422.1", "url": "https://www.ensembl.org/id/ENSGALP00010009422.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U045-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 73, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U045-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U045" } ], "lectin_list": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U0D0-1", "uniprot_ac": "A0A3Q2U0D0", "uniprot_id": "A0A3Q2U0D0_CHICK", "mass": { "chemical_mass": 15644.0, "monoisotopic_mass": 15644.0 }, "refseq": { "ac": "XP_414410", "name": "uncharacterized protein C3orf14 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414410" }, "gene_names": [ { "name": "C3orf14", "type": "recommended", "evidence": [ { "id": "A0A3Q2U0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0" } ] }, { "name": "C3orf14", "type": "synonym", "evidence": [ { "id": "XP_414410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414410" } ] } ], "protein_names": [ { "name": "Centrosomal protein 15", "type": "synonym", "evidence": [ { "id": "A0A3Q2U0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C3orf14 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_414410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414410" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414410" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0D0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C3orf14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U0D0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U0D0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000048873", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000048873", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416073", "url": "https://www.ncbi.nlm.nih.gov/gene/416073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416073", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEYIPKW", "url": "https://omabrowser.org/oma/group/KEYIPKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U0D0", "url": "https://www.orthodb.org/?gene=A0A3Q2U0D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA16", "url": "https://www.orthodb.org/?gene=A0A8V0ZA16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14286:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14286:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0D0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSYLAQEVHLARRHEEILSQRSALLQQMETYLGDKKTKKTWQTQAADAARRRNAALLNDIEAAEKKLQERMYLLPHPDTVKLETLYWASVKESLPNWEEFLLGRAEYPIGIKKLKTTKQNISYPEEDSQKQIL", "length": 134, "header": "tr|A0A3Q2U0D0-1|A0A3Q2U0D0_CHICK Isoform 1 of Centrosomal protein 15 OS=Gallus gallus OX=9031 GN=C3orf14 PE=4 SV=1 CANONICAL=A0A3Q2U0D0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0D0/entry", "sequence": { "sequence": "MSSYLAQEVHLARRHEEILSQRSALLQQMETYLGDKKTKKTWQTQAADAARRRNAALLNDIEAAEKKLQERMYLLPHPDTVKLETLYWASVKESLPNWEEFLLGRAEYPIGIKKLKTTKQNISYPEEDSQKQIL", "length": 134, "header": "tr|A0A3Q2U0D0-1|A0A3Q2U0D0_CHICK Isoform 1 of Centrosomal protein 15 OS=Gallus gallus OX=9031 GN=C3orf14 PE=4 SV=1 CANONICAL=A0A3Q2U0D0-1" }, "locus": { "chromosome": "12", "start_pos": 13314060, "end_pos": 13305608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050937.1", "url": "https://www.ensembl.org/id/ENSGALT00010050937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030128.1", "url": "https://www.ensembl.org/id/ENSGALP00010030128.1" } ] } }, { "isoform_ac": "A0A8V0ZA16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA16/entry", "sequence": { "sequence": "MSSYLAQEVHLARRHEEILSQRSALLQQMETYLGDKKTKKTWQTQAADAARRRNAALLNTLYWASVKESLPNWEEFLLGRAEYPIGIKKLKTTKQNISYPEEDSQKQIL", "length": 109, "header": "tr|A0A8V0ZA16-1|A0A8V0ZA16_CHICK Computationally mapped isoform of Centrosomal protein 15 OS=Gallus gallus OX=9031 GN=C3orf14 PE=4 SV=1 CANONICAL=A0A3Q2U0D0-1" }, "locus": { "chromosome": "12", "start_pos": 13314060, "end_pos": 13305608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050939.1", "url": "https://www.ensembl.org/id/ENSGALT00010050939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030130.1", "url": "https://www.ensembl.org/id/ENSGALP00010030130.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416073", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416073", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUN2-1", "protein_name": "Centrosomal protein 15", "gene_name": "Cep15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLFTQEVHLSKRHEEIVSQRLMLLQKMKNKFGDQSTERASLQATETACRRNLQLLQDIDVAEKAFQTKLTPHPQPEMLSLETRYWASVEEHVPKWEQFLLGKALIQYVPVSGRLRMVLKNESWEWLLNSDRLI", "length": 135 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EZM5-1", "protein_name": "Centrosomal protein 15", "gene_name": "cep15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASYTVEEFELSQKHEDILGKRALLLQQMEAHYEQQRAKRKQQFLMCQAAKQRNAQILKDLENVEKNLQTRQLLHPNIISLETRYWASVERNLPEWEQYLLGKGQPPLSESEKKLKQQRLKTAQQDPSPAQCRGKPPRPKP", "length": 141 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SGF9-1", "protein_name": "Centrosomal protein 15", "gene_name": "CEP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSLFAEEICLSKRHEEIVSQRLMLLQQMENKLGDQNKEKASQRQAAENAFKRNLSLLKDIEAAEESLQTRIHALPPPEVVSLETLYWASVEEYIPKWEQFLLGRAPYPIGVENQIEAENTIQNKAAIASSHTVSKNLSSKAEH", "length": 144 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q29S20-1", "protein_name": "Centrosomal protein 15", "gene_name": "CEP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSLFTQEIRLSKRHEKIVSQRLMLLQQMENKPEDQNKGRASQTQAAKAALQRNVSLLKDIEAAEKSLQTRMYPALPPEVAALETLYWASVEEYIPKWEQFLLGRAPYPACSENGNEAEDTIPKRAQQ", "length": 128 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BGD0-1", "protein_name": "Centrosomal protein 15", "gene_name": "Cep15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFTQEIHLSKRHEEILSQRLMLLQKMKNKFGDENTERASLLQATETASRRNLRLLKDIDAAEEAFQTKLIPHPQPSMLSLETRYWASVEEHIPKWELFLLGRAPYPIGAENQNEVPFVQTEAKL", "length": 127 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBI5-1", "protein_name": "Centrosomal protein 15", "gene_name": "CEP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSLFAQEIRLSKRHEEIVSQRLMLLQQMENKLGDQHTEKASQLQTVETAFKRNLSLLKDIEAAEKSLQTRIHPLPRPEVVSLETRYWASVEEYIPKWEQFLLGRAPYPFAVENQNEAENTIQNEAQR", "length": 128 }, "evidence": [ { "id": "A0A3Q2U0D0", "url": "https://omabrowser.org/oma/group/A0A3Q2U0D0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U0D0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 134, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U0D0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U0D0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U0F1-1", "uniprot_ac": "A0A3Q2U0F1", "uniprot_id": "A0A3Q2U0F1_CHICK", "mass": { "chemical_mass": 59557.0, "monoisotopic_mass": 59557.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2U0F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U0F1", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U0F1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000048907", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000048907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKGKIPSTHHATDATWSKWIALITQRARMGNFSRPGILEVIMDWPEGKKFETSPGEEVSRAKEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEATEGKGESSQFAEVKAVQLALDVAEREGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAARIKNMVVKVRHVDAHVPKSRATEEQKNNHHVDQAAKIEVAQIDLDWQNKGELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCETCAIIKQAKRMKPLWEEGRWQKYKYGEAWQIDYITLPRSCNGKRYVLTMVEATTGWLETYAVPHATARNTILGLEKQVLWRHGTPERIESDNGTHFKNSLINTWAKEHGIEWIYHIPYHAPASGKIERYNGLLKTMLKAMGGGTFKHWEKHLAEATWLVNTRGSINRDGPTHSSSLHTVEGDKVPVVHVKSMLGKAVWVLPASGKGRPLRGTVFAQGPGSTWWVMQKDGDVQCVPQGNLMLGECSQ", "length": 523, "header": "tr|A0A3Q2U0F1-1|A0A3Q2U0F1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U0F1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U0F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1/entry", "sequence": { "sequence": "MFKGKIPSTHHATDATWSKWIALITQRARMGNFSRPGILEVIMDWPEGKKFETSPGEEVSRAKEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEATEGKGESSQFAEVKAVQLALDVAEREGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAARIKNMVVKVRHVDAHVPKSRATEEQKNNHHVDQAAKIEVAQIDLDWQNKGELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCETCAIIKQAKRMKPLWEEGRWQKYKYGEAWQIDYITLPRSCNGKRYVLTMVEATTGWLETYAVPHATARNTILGLEKQVLWRHGTPERIESDNGTHFKNSLINTWAKEHGIEWIYHIPYHAPASGKIERYNGLLKTMLKAMGGGTFKHWEKHLAEATWLVNTRGSINRDGPTHSSSLHTVEGDKVPVVHVKSMLGKAVWVLPASGKGRPLRGTVFAQGPGSTWWVMQKDGDVQCVPQGNLMLGECSQ", "length": 523, "header": "tr|A0A3Q2U0F1-1|A0A3Q2U0F1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U0F1-1" }, "locus": { "chromosome": "4", "start_pos": 70749824, "end_pos": 70748256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027913.1", "url": "https://www.ensembl.org/id/ENSGALT00010027913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016015.1", "url": "https://www.ensembl.org/id/ENSGALP00010016015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0F1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U0F1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 523, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U0F1-F1.pdb", "url_external": 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"MDLNKHTWDGLPVSRDPVTIAMNVPFFNDPPGPVGVPGKPLRKLCDYEVVEAFFLSDRAEQDLEVELCKCSLLKNVTKTETKRAGRAHLPWSYCPLCTSKFNAFAIYGSREQRKYEVLFAVPQHKLCEGQKPDL", "length": 134, "header": "tr|A0A3Q2U0Q8-1|A0A3Q2U0Q8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A3Q2U0Q8-1" }, "locus": { "chromosome": "8", "start_pos": 16238673, "end_pos": 16236722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050478.1", "url": "https://www.ensembl.org/id/ENSGALT00010050478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029795.1", "url": "https://www.ensembl.org/id/ENSGALP00010029795.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_046770637" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046770637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770637" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0V5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPCEF1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U0V5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U0V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013625", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013625", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01260", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR12844:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12844:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046770637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0V5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UD10", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD10-1", 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"id": "A0A8V0XSP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVDRTSVALRQNSLVVPLRQKAKKKSQGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 432, "header": "tr|A0A3Q2U0V5-1|A0A3Q2U0V5_CHICK Isoform 1 of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5/entry", "sequence": { "sequence": "MGVDRTSVALRQNSLVVPLRQKAKKKSQGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 432, "header": "tr|A0A3Q2U0V5-1|A0A3Q2U0V5_CHICK Isoform 1 of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49815481, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012505.1", "url": "https://www.ensembl.org/id/ENSGALT00010012505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007069.1", "url": "https://www.ensembl.org/id/ENSGALP00010007069.1" } ] } }, { "isoform_ac": "A0A3Q2UD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UD10/entry", "sequence": { "sequence": "MEADGNALVPLRQKAKKKSQGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 424, "header": "tr|A0A3Q2UD10-1|A0A3Q2UD10_CHICK Computationally mapped isoform of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49800261, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012511.1", "url": "https://www.ensembl.org/id/ENSGALT00010012511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007075.1", "url": "https://www.ensembl.org/id/ENSGALP00010007075.1" } ] } }, { "isoform_ac": "A0A8V0XMM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMM3/entry", "sequence": { "sequence": "MPVRSKHATEVPLRQKAKKKSQGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 426, "header": "tr|A0A8V0XMM3-1|A0A3Q2U0V5_CHICK Computationally mapped isoform of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49820633, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012517.1", "url": "https://www.ensembl.org/id/ENSGALT00010012517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007081.1", "url": "https://www.ensembl.org/id/ENSGALP00010007081.1" } ] } }, { "isoform_ac": "A0A8V0XQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQB8/entry", "sequence": { "sequence": "MFLLKGSRGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 412, "header": "tr|A0A8V0XQB8-1|A0A3Q2U0V5_CHICK Computationally mapped isoform of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49795655, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012498.1", "url": "https://www.ensembl.org/id/ENSGALT00010012498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007062.1", "url": "https://www.ensembl.org/id/ENSGALP00010007062.1" } ] } }, { "isoform_ac": "A0A8V0XSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSN1/entry", "sequence": { "sequence": "MTTCCFFGRNLCGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 416, "header": "tr|A0A8V0XSN1-1|A0A3Q2U0V5_CHICK Computationally mapped isoform of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49795851, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012501.1", "url": "https://www.ensembl.org/id/ENSGALT00010012501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007065.1", "url": "https://www.ensembl.org/id/ENSGALP00010007065.1" } ] } }, { "isoform_ac": "A0A8V0XSP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSP6/entry", "sequence": { "sequence": "MMEFIAFWVPLRQKAKKKSQGFFIMSRRRISCKELGQADCQGWLYKKKEKGAFIGNKWKKFWCVLKESSLYWYSSQLAEKAEGFIRLPDFSVDRATECKKKHAIKISHPQIKTFYFAAENVLEMNTWLSKLGMAIDPQAPNGKSEEECYSESEHDDPEITDTPPHPYAAQPPPPHLDQQKSSLTSTLSSEASCSLSSPESTFNSQESSSSLTSKVVYSERQSLLDFVNNSAMEDCDQPLTFCVQIQSDEQPEVDCGETAQSQICPGSGPENTFLGLSTHCLTVPDAAGQISLAKDHEKCDDDEMERLYKSLEQASLSPIGDRRLSTKKELRKSFIKRSKNPSINEKLHKIRMLNSTLKCKEHDLATINQLLEDPKLTAMKYREWRNTNIMLVQDIYQQQEVQDVSTENSEEQETAPLPVTESAT", "length": 424, "header": "tr|A0A8V0XSP6-1|A0A3Q2U0V5_CHICK Computationally mapped isoform of Interaction protein for cytohesin exchange factors 1 OS=Gallus gallus OX=9031 GN=IPCEF1 PE=4 SV=1 CANONICAL=A0A3Q2U0V5-1" }, "locus": { "chromosome": "3", "start_pos": 49820241, "end_pos": 49761668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012516.1", "url": "https://www.ensembl.org/id/ENSGALT00010012516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007080.1", "url": "https://www.ensembl.org/id/ENSGALP00010007080.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421645", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421645", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5DU31-1", "protein_name": "Interactor protein for cytohesin exchange factors 1", "gene_name": "Ipcef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGSSLYWYSNQMAEKADGFVNLSDFTVERASECKKKNAFKINHPQIKAFYFAAENLQEMNVWLNKLGFAVTHQESITKDEECYSESEQEDPEVAVEAPPPPYASTTSSPVAAQWASSSSPKRRETSCSFSSLENTVKAPSQFSSSGSKERQSWHNIVNSSPATEDAGLPLTFAEQVHTLAFSEASNCQAPENNCITSEGGLLNLLSSDDTSSLNNNKDHLTVPDRAAGSRMADREEIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQAPQDPEVTPQEVMNPTSSDCVENSL", "length": 406 }, "evidence": [ { "id": "A0A3Q2U0V5", "url": "https://omabrowser.org/oma/group/A0A3Q2U0V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VL0-1", "protein_name": "Interactor protein for cytohesin exchange factors 1", "gene_name": "Ipcef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGSSLYWYGNQLAEKADGFVNLPDFTVERASECKKKNAFKINHPQIKTFYFAAENLQEMNMWLNKLGFAVTHKESTTKDEECYSESEQEDPETAVEAPPPPSASATSSPVAARRASSSSPKRRETSCSFSSLENTVKAPSRFSSSGSKERQSWLDIVNSSPATEDVGHPLSFAVQVHTLASSEASSCRVSENSSTTPESGCLNSLSSDDTSSLNNSQDHLTVPDRASGSRMTDRDEIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQVPQDPEVTPQEIMNPTSSDCVENSL", "length": 406 }, "evidence": [ { "id": "A0A3Q2U0V5", "url": "https://omabrowser.org/oma/group/A0A3Q2U0V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WWN9-1", "protein_name": "Interactor protein for cytohesin exchange factors 1", "gene_name": "IPCEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITFAVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIMDKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQRASPAPDDTDDTPQELKKSPSSPSVENSI", "length": 437 }, "evidence": [ { "id": "A0A3Q2U0V5", "url": "https://omabrowser.org/oma/group/A0A3Q2U0V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0V5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "enzyme-linked receptor protein signaling pathway", "id": "GO:0007167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007167", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U0V5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U0V5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 432, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U0V5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U0V5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U1C9-1", "uniprot_ac": "A0A3Q2U1C9", "uniprot_id": "A0A3Q2U1C9_CHICK", "mass": { "chemical_mass": 6915.0, "monoisotopic_mass": 6915.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A3Q2U1C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1C9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U1C9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U1C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000049209", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049209", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U1C9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLGTDGNTLIRVVVFRLKIDILDIGRELLTMYGKSLYSFIKGDCSGDYRNVLLKLCGSED", "length": 62, "header": "tr|A0A3Q2U1C9-1|A0A3Q2U1C9_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A3Q2U1C9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U1C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1C9/entry", "sequence": { "sequence": "MKGLGTDGNTLIRVVVFRLKIDILDIGRELLTMYGKSLYSFIKGDCSGDYRNVLLKLCGSED", "length": 62, "header": "tr|A0A3Q2U1C9-1|A0A3Q2U1C9_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A3Q2U1C9-1" }, "locus": { "chromosome": "6", "start_pos": 964217, "end_pos": 963051, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023491.1", "url": "https://www.ensembl.org/id/ENSGALT00010023491.1" }, { 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This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415054" } ] }, { "annotation": "Can influence paracellular permeability. 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} ], "crossref": [ { "id": "A0A3Q2U1Q9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U1Q9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029047", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029047", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416759", "url": "https://www.ncbi.nlm.nih.gov/gene/416759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416759", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKSCWLA", "url": "https://omabrowser.org/oma/group/WKSCWLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U1Q9", "url": "https://www.orthodb.org/?gene=A0A3Q2U1Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14627:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14627:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_415054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVQKLVATAVLVALVSLILNNAAAFTPNWVYQTLEDGRKRSVGLWKMCWLAERSRAGASTSSRHGQGEERECEALGWGSESAGFQESRSTVKLQFDMMRACNLIATVALTAGQLIFVLGLVEIPIISQDTQWWEEAIAAVFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAILIWNILHRREDCMAPRVIVISRTLTARFRRGLENDYVESPC", "length": 226, "header": "tr|A0A3Q2U1Q9-1|A0A3Q2U1Q9_CHICK Isoform 1 of Transmembrane protein 204 OS=Gallus gallus OX=9031 GN=TMEM204 PE=4 SV=1 CANONICAL=A0A3Q2U1Q9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U1Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9/entry", "sequence": { "sequence": "MTVQKLVATAVLVALVSLILNNAAAFTPNWVYQTLEDGRKRSVGLWKMCWLAERSRAGASTSSRHGQGEERECEALGWGSESAGFQESRSTVKLQFDMMRACNLIATVALTAGQLIFVLGLVEIPIISQDTQWWEEAIAAVFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAILIWNILHRREDCMAPRVIVISRTLTARFRRGLENDYVESPC", "length": 226, "header": "tr|A0A3Q2U1Q9-1|A0A3Q2U1Q9_CHICK Isoform 1 of Transmembrane protein 204 OS=Gallus gallus OX=9031 GN=TMEM204 PE=4 SV=1 CANONICAL=A0A3Q2U1Q9-1" }, "locus": { "chromosome": "14", "start_pos": 13796778, "end_pos": 13770829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042042.1", "url": "https://www.ensembl.org/id/ENSGALT00010042042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024612.1", "url": "https://www.ensembl.org/id/ENSGALP00010024612.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R6J6-1", "protein_name": "Transmembrane protein 204", "gene_name": "tmem204", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVRRLVELAAAVALLSLVLNSVATFSSGWVLQVLDDGRRRSVGLWRACVQEDTHTHELTACQRLSWGSELAGYQESRSTVKLQFDMMRACNLMATVALTVGQLIFLFGLLEISHITQDSQWWEEAIAALFQLASFVLVIGLVTFYRIGPYTHLSYSCYINIAACLFATLAAAMLIWNILHRRDDCLSPSVIVISRSLTTPFRPRLDNDYVESPC", "length": 215 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RG12-1", "protein_name": "Transmembrane protein 204", "gene_name": "TMEM204", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTVQKVVATAVLVALVSLVLNNVAALTPNWVYQTLEDGRRRSVGLWRSCWLLDRARGGPSPGARPGPADTRDCEALGWGSEAAGFQESRGTVKLQFDMMRACNLVATAALAAGQLTFVLGLTGLPLMSPDSQCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTNLSWSCYLDIGACLLATLAAAMLIWNVLHRREDCMAPRVIVISRSLAARFRRGLDNDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HBY0-1", "protein_name": "Transmembrane protein 204", "gene_name": "Tmem204", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTVQKLVATAVLVALVSLILNNAAAFTPNWVYQTLEDGRKRSVGLWRSCWLVDRGKGGTSPGARTGQVDTHDCEVLGWGSESAGFQESRGTVKLQFDMMRACNLVATAALAVGQLTFVLGLTGLPLVSPESQCWAEAMAAAFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAMLIWNILHRREDCMAPRVIVISRSLTARFRRGLENDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0IIE5-1", "protein_name": "Transmembrane protein 204", "gene_name": "TMEM204", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTVRKVVATAVLVALVSLVLNNAAAFTPNWVYQTLEDGRRRSVGLWWACWLVERPRGAPGPGARPGPADVRDCEALGWGSEAAGFQESRGTVKLQFDMMRACNLVATAALAAGQLTFVLGLTGLPLLSPDAQCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTSLSWSCYLNIGACLLATLAAAMLIWNVLHRREDCTAPRVIVISRSLTARFRRGLDNDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M962-1", "protein_name": "Transmembrane protein 204", "gene_name": "Tmem204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQKLVATAVLVALVSLILNNAAAFTPNWVYQTLEDGRKRSVGLWKSCWLVDRGKGGTSPGTRTGQVDTHDCEVLGWGSESAGFQESRGTVKLQFDMMRACNLVATAALAVGQITFILGLTGLPLMSPESQCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAMLIWNILHRREDCMAPRVIVISRSLTARFRRGLDNDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQI0-1", "protein_name": "Transmembrane protein 204", "gene_name": "Tmem204", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLQKLVATAVLVALVSLILNNAAAFTPNWVYQTLEDGRKRSVGLWKSCWLVDRGKGVTSPGTRTGQVDTHDCEVLGWGSESAGFQESRGTVKLQFDMMRACNLVATAALVVGQITFILGLTGLPLMSPESQCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAMLIWNILHRREDCMAPRVIVISRSLTARFRRGLDNDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSN7-1", "protein_name": "Transmembrane protein 204", "gene_name": "TMEM204", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVQRLVAAAVLVALVSLILNNVAAFTSNWVCQTLEDGRRRSVGLWRSCWLVDRTRGGPSPGARAGQVDAHDCEALGWGSEAAGFQESRGTVKLQFDMMRACNLVATAALTAGQLTFLLGLVGLPLLSPDAPCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTNLSWSCYLNIGACLLATLAAAMLIWNILHKREDCMAPRVIVISRSLTARFRRGLDNDYVESPC", "length": 226 }, "evidence": [ { "id": "A0A3Q2U1Q9", "url": "https://omabrowser.org/oma/group/A0A3Q2U1Q9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9" } ], "pmid": "" }, { "name": "regulation of vascular endothelial growth factor receptor signaling pathway", "id": "GO:0030947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030947", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U1Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U1Q9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 226, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U1Q9-F1.pdb", "url_external": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U207-1", "uniprot_ac": "A0A3Q2U207", "uniprot_id": "A0A3Q2U207_CHICK", "mass": { "chemical_mass": 8433.0, "monoisotopic_mass": 8433.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "protein-serine/threonine phosphatase", "type": "recommended", "evidence": [ { "id": "A0A3Q2U207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A3Q2U207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U207", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U207", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U207", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054217", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054217", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029052", "url": 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"isoform_ac": "A0A3Q2U207-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207/entry", "sequence": { "sequence": "MAEAEVRGSCIKSQEIFLSQPVLLELEVPLKTCGDVHGQHTALLQLCGYGRFYIRSLSWSPEGCAPRHSRAGSVLFG", "length": 77, "header": "tr|A0A3Q2U207-1|A0A3Q2U207_CHICK Isoform 1 of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U207-1" }, "locus": { "chromosome": "4", "start_pos": 48667158, "end_pos": 48666928, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010483.1", "url": "https://www.ensembl.org/id/ENSGALT00010010483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006111.1", "url": "https://www.ensembl.org/id/ENSGALP00010006111.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U207", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U207", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U207-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 77, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U207-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U207" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U207" }, { "id": "PF16891", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16891" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine-threonine protein phosphatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 27, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U8V0-1", "uniprot_ac": "A0A3Q2U8V0", "uniprot_id": "A0A3Q2U8V0_CHICK", "mass": { "chemical_mass": 134301.0, "monoisotopic_mass": 134301.0 }, "refseq": { "ac": "XP_004947642", "name": "rab11 family-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947642" }, "gene_names": [ { "name": "RAB11FIP1", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ] }, { "name": "RAB11FIP1", "type": "synonym", "evidence": [ { "id": "XP_004947642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947642" } ] } ], "protein_names": [ { "name": "Rab11 family-interacting protein 2", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0/entry#names_and_taxonomy" } ] }, { "name": "rab11 family-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004947642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947642" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947642" } ] }, { "annotation": "A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U263", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U263#function" }, { "database": "UniProtKB", "id": "ARBA00055128", "url": "https://www.uniprot.org/uniprotkb/ARBA00055128#function" }, { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB11FIP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0", "locus": { "chromosome": "22", "start_pos": 2390186, "end_pos": 2402142, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017411", "url": "https://www.ensembl.org/id/ENSGALG00010017411" } ] } } ], "crossref": [ { "id": "A0A3Q2U8V0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8V0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003129", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003129", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770622", "url": "https://www.ncbi.nlm.nih.gov/gene/770622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770622", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPFASEW", "url": "https://omabrowser.org/oma/group/NPFASEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U263", "url": "https://www.orthodb.org/?gene=A0A3Q2U263", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U8V0", "url": "https://www.orthodb.org/?gene=A0A3Q2U8V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U263", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U263", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U263-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U263-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPAPRWVPTHVQVTVLQARGLRSKAAEGQGGSDAYAVMAVGRDKFSTSVAERCQGQPLWREEATFELPPPPRPAALRLTVLHRALVGLDKFLGRADVDLAALREDGGRRHCRWYKLRSKPGKKEKERGEIEVDIQFMRSNLTASMFDLSMKDKARSPFGKLKDKLKGKRSSGLSDTASAIVPSTTHSPADSEDEASEKEKKKSKFKTLFSKPGLQKTSLSQSLSVLPTPQPVAAGVRLRPRDFQPQWDDEDLETSPTSERTFEIALDEKSSPVFKPRKAATLDSRQLNQPAAGNTKKEGLSLFSGLKSKNDPVSKSSLCINGSHVYMEENTLKDSTPASSPSPRNFRKKQGSASEENLSSRSTKGPEEMGRTSPSYALSGSASLETFKAMSLPSYKLLSGEEYVENSPPVSVEVTRETKKTDQKKSALLSLVTGKKEAVKNSDAESIPDRSQKEEENKDAEEKSEQEAKCLEPPADVSRGNPSEDTQPEVFTSKQLLNPFEEERKPEKAAAPAKTKAVKPRLGVSSEEETKATLPTLAPDSLPAYLSVHHISSDNNPFVSKMGQKVPDSEGVTSASLPSPFTEELLSGKNPFNPSWGRVSPALGSDHVVIPSSHHLAASTPKGQISRSGNNPFASEWGQGPEGSDAHASVSPLPVPSPRSGGHFNGNNPFISKTGWVADAPGLTAVTASSPVGLPGDGDNSSAGLSADLSYSAVTASGSSSSVASTHNVNAVANPPDAPSVNPGVAPKNQCDSVQVQVGPSLNRSKLVLFAENGAEQPPSSESELKEKQELWSEKRREEHSPPSEPQEAPPDTKESSPVGSVNPTLGAHTQPPRETAAGRAGREGAVTPQPAPRLSLMQKCPPVSQADELSVGPSGEGEGSACGLALQNEKAPGAHEYLPQNGSVTALVPPVKLRADSSSRCVKKEGDEDLFDSLTNLKSALSVTGDHSVRLAALPAIPEAGSDDELQGDCQENQGIAADGQNVLESVDRTPLHENQKESSLSSAAGGVTLSAGGGSAVPVLPAGGHGHGVSKQTPDSGMTSHSSEHSCCFEKQVISTGAGKRAESDFFEPSVSSSSLSCSSQPCSSSHSLSSDTPSQRAESPKKPTAEGFADKAGNSGKKKLLQAWVSPSETYPNQTQQSGETMSPKHRLHPVKPMNTTANKTQSKDLNVISAMNEKLLEMNIKKYNPSDPAYAYAQLTHDELIQLVLKQKDTITKKDLQVRELEDYIDNLLVRVMEETPNILRVSTSGNRKAGKM", "length": 1259, "header": "tr|A0A3Q2U8V0-1|A0A3Q2U8V0_CHICK Isoform 1 of Rab11 family-interacting protein 2 OS=Gallus gallus OX=9031 GN=RAB11FIP1 PE=1 SV=1 CANONICAL=A0A3Q2U8V0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U263-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U263/entry", "sequence": { "sequence": "MEAPAPRWVPTHVQVTVLQARGLRSKAAEGQGGSDAYAVMAVGRDKFSTSVAERCQGQPLWREEATFELPPPPRPAALRLTVLHRALVGLDKFLGRADVDLAALREDGGRRHCRWYKLRSKPGKKEKERGEIEVDIQFMRSNLTASMFDLSMKDKARSPFGKLKDKLKGKRSSGLSDTASAIVPSTTHSPADSEDEASEKEKKKSKFKTLFSKPGLQKTSLSQSLSVLPTPQPVAAGVRLRPRDFQPQWDDEDLETSPTSERTFEIALDEKSSPVFKPRKAATLDSRQLNQPAAGNTKKEGLSLFSGLKSKNDPVSKSSLCINGSHVYMEENTLKDSTPASSPSPRNFRKKQGSASEENLSSRSTKGPEEMGRTSPSYALSGSASLETFKAMSLPSYKLLSGEEYVENSPPVSVEVTRETKKTDQKKSALLSLVTGKKEAVKNSDAESIPDRSQKEEENKDAEEKSEQEAKCLEPPADVSRGNPSEDTQPEVFTSKQLLNPFEEERKPEKAAAPAKTKAVKPRLHPVKPMNTTANKTQSKDLNVISAMNEKLLEMNIKKYNPSDPAYAYAQLTHDELIQLVLKQKDTITKKDLQVRELEDYIDNLLVRVMEETPNILRVSTSGNRKAGKM", "length": 630, "header": "tr|A0A3Q2U263-1|A0A3Q2U8V0_CHICK Computationally mapped isoform of Rab11 family-interacting protein 2 OS=Gallus gallus OX=9031 GN=RAB11FIP1 PE=1 SV=1 CANONICAL=A0A3Q2U8V0-1" }, "locus": { "chromosome": "22", "start_pos": 2402045, "end_pos": 2392976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042019.1", "url": "https://www.ensembl.org/id/ENSGALT00010042019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024597.1", "url": "https://www.ensembl.org/id/ENSGALP00010024597.1" } ] } }, { "isoform_ac": "A0A3Q2U8V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0/entry", "sequence": { "sequence": "MEAPAPRWVPTHVQVTVLQARGLRSKAAEGQGGSDAYAVMAVGRDKFSTSVAERCQGQPLWREEATFELPPPPRPAALRLTVLHRALVGLDKFLGRADVDLAALREDGGRRHCRWYKLRSKPGKKEKERGEIEVDIQFMRSNLTASMFDLSMKDKARSPFGKLKDKLKGKRSSGLSDTASAIVPSTTHSPADSEDEASEKEKKKSKFKTLFSKPGLQKTSLSQSLSVLPTPQPVAAGVRLRPRDFQPQWDDEDLETSPTSERTFEIALDEKSSPVFKPRKAATLDSRQLNQPAAGNTKKEGLSLFSGLKSKNDPVSKSSLCINGSHVYMEENTLKDSTPASSPSPRNFRKKQGSASEENLSSRSTKGPEEMGRTSPSYALSGSASLETFKAMSLPSYKLLSGEEYVENSPPVSVEVTRETKKTDQKKSALLSLVTGKKEAVKNSDAESIPDRSQKEEENKDAEEKSEQEAKCLEPPADVSRGNPSEDTQPEVFTSKQLLNPFEEERKPEKAAAPAKTKAVKPRLGVSSEEETKATLPTLAPDSLPAYLSVHHISSDNNPFVSKMGQKVPDSEGVTSASLPSPFTEELLSGKNPFNPSWGRVSPALGSDHVVIPSSHHLAASTPKGQISRSGNNPFASEWGQGPEGSDAHASVSPLPVPSPRSGGHFNGNNPFISKTGWVADAPGLTAVTASSPVGLPGDGDNSSAGLSADLSYSAVTASGSSSSVASTHNVNAVANPPDAPSVNPGVAPKNQCDSVQVQVGPSLNRSKLVLFAENGAEQPPSSESELKEKQELWSEKRREEHSPPSEPQEAPPDTKESSPVGSVNPTLGAHTQPPRETAAGRAGREGAVTPQPAPRLSLMQKCPPVSQADELSVGPSGEGEGSACGLALQNEKAPGAHEYLPQNGSVTALVPPVKLRADSSSRCVKKEGDEDLFDSLTNLKSALSVTGDHSVRLAALPAIPEAGSDDELQGDCQENQGIAADGQNVLESVDRTPLHENQKESSLSSAAGGVTLSAGGGSAVPVLPAGGHGHGVSKQTPDSGMTSHSSEHSCCFEKQVISTGAGKRAESDFFEPSVSSSSLSCSSQPCSSSHSLSSDTPSQRAESPKKPTAEGFADKAGNSGKKKLLQAWVSPSETYPNQTQQSGETMSPKHRLHPVKPMNTTANKTQSKDLNVISAMNEKLLEMNIKKYNPSDPAYAYAQLTHDELIQLVLKQKDTITKKDLQVRELEDYIDNLLVRVMEETPNILRVSTSGNRKAGKM", "length": 1259, "header": "tr|A0A3Q2U8V0-1|A0A3Q2U8V0_CHICK Isoform 1 of Rab11 family-interacting protein 2 OS=Gallus gallus OX=9031 GN=RAB11FIP1 PE=1 SV=1 CANONICAL=A0A3Q2U8V0-1" }, "locus": { "chromosome": "22", "start_pos": 2402045, "end_pos": 2392976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042018.1", "url": "https://www.ensembl.org/id/ENSGALT00010042018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024596.1", "url": "https://www.ensembl.org/id/ENSGALP00010024596.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 230, "start_aa": "Thr", "end_pos": 230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr230", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 717, "start_aa": "Thr", "end_pos": 717, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr717", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:770622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770622", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N1R3-1", "protein_name": "Rab11 family-interacting protein 1", "gene_name": "RAB11FIP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLAASAGRGPGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPPLLSAEAAPAAAATLQLTVLHRALLGLDKFLGRAEVDLRGLHQNQGRRRTQWYTLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSASDTVSAIVPHVTPSADSDDEAPSKDKKKKSKIKTLFSKSNLQRTPLSQSMSVLPTSKSDKVMLRPGDFESRWEDDDEDESSSASDVLSHKRTASADPKQLNQVNFSLPKKEGLSFLGGLRSKNDALSRSNVCINGNHVYVEPPEAKTETKDVSPSPSPSPQDLRKKRWFSSTENLASRPWREPGEAGAVPPESSTKDALKSMSLPSYQPQVSRDLRENAAPATLEAAKETKESKKQENKKPALPFLVPGKKDTAKGSEGESPPAAASGKEREGAPTALRAGEHQPGPADDLVKKSDKEAAPVAAGPGRALNPFEDEQLPEPEADPEPKAAPVPPVFSPRAPQTRAVKPRLHPVKPMNTTAPKVSNSTSGTTAIVSENLINEAGMKKYKPSDPAFAYAQLTHDELIQLVLKQKETISKKECQVRQLEDYIDNLLVRVMEETPNILRVPSQVGKKAGKM", "length": 644 }, "evidence": [ { "id": "A0A3Q2U8V0", "url": "https://omabrowser.org/oma/group/A0A3Q2U8V0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3B7T9-1", "protein_name": "Rab11 family-interacting protein 1", "gene_name": "Rab11fip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLAASAGRGPGTMWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPPLLSSGTAPAAAAATLQLTVLHRALLGLDKFLGRAEVDLRELHRDQSRRKKQWYTLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDNTSDTASAIVPSTTPSVDSDDESFSKDKKKKSKIKTLFSKPSLQKTPLSQSMSVLPTSKPDKVLLRPGDFQSRWGDEGDNEDESSSASEVMSQKRTSSTDHTQPNQSNFSLPKKEGLSFLGGLRSKNDSLSRSNVCINGNHVYMEQPEAKSEIRESSPSNSPSPQGFRKRHLFSSTENLAARSPKEPGEGGGMSSDRRLSDSSTKDSMKSMSLPSYRPLTTADSREGLSPANMEVATKETKDSKKQESKKSSLLSLVTGKKDVAKGSEGEPLPPVSEKEKGRKGVLVEAQLREEDLVRRPEKDAVPVASQWGSSQNPFEDAQISDLEASVESKCEPKPPVPVPRTPQTRAVKPRPHPVKPMNTTAPKITNSSLGTATIISENLINEALMKKYQPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRVPAQTGKKAGKM", "length": 648 }, "evidence": [ { "id": "A0A3Q2U8V0", "url": "https://omabrowser.org/oma/group/A0A3Q2U8V0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6WKZ4-4", "protein_name": "Rab11 family-interacting protein 1", "gene_name": "RAB11FIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSALGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQVGKKAGKM", "length": 1283 }, "evidence": [ { "id": "A0A3Q2U8V0", "url": "https://omabrowser.org/oma/group/A0A3Q2U8V0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D620-1", "protein_name": "Rab11 family-interacting protein 1", "gene_name": "Rab11fip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLAASAGRGPGTMWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPPLLSSGAAPAAAATLQLTVLHRALLGLDKFLGRAEVDLRELHRDQGRRKKQWYTLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSASDTASAIVPSVTPSVDSDDESFSKDKKKKSKIKTLFSKSSLQKTPLSQSMSVLPTSKSDKVLLRAGDFQSQWDDDAHEDESSSASDVMSHKRTSSTDQQPNQSNFSLPKKEGLSFLGGLRSKNDSLSRSTVCINGNHVYMEQPEARSEIRESSPSNSPSPQGFRRKHLFSSTENLAARSPKEPGEGGGTSSDRRLSDSSTKDSMKSMSLPSYRPLTSGDNRESMSPANVEAARETKDSKKQESKKSSLLSLVTGKRDAAAKGSESEPLPTVSEKEKERKGALVEAQLREEDLMRRPEKDALPVASQWGSSLNPFEDVQISDPGATTESRSEPKPPVPAARVPQTKAVKPRPHPVKPMNTTATKIANSSLGTATIITENLISEALMKKYQPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRVPAQMGKKAGKM", "length": 645 }, "evidence": [ { "id": "A0A3Q2U8V0", "url": "https://omabrowser.org/oma/group/A0A3Q2U8V0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "negative regulation of adiponectin secretion", "id": "GO:0070164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070164", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8V0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1138, "end_pos": 1140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U8V0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1259, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U8V0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8V0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 230, 717 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1138, "end_pos": 1140 }, { "start_pos": 1160, "end_pos": 1162 }, { "start_pos": 1164, "end_pos": 1166 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 702, "end_pos": 704 }, { "start_pos": 765, "end_pos": 767 }, { "start_pos": 904, "end_pos": 906 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U2N2-1", "uniprot_ac": "A0A3Q2U2N2", "uniprot_id": "A0A3Q2U2N2_CHICK", "mass": { "chemical_mass": 33022.0, "monoisotopic_mass": 33022.0 }, "refseq": {}, "gene_names": [ { "name": "LOC428667", "type": "recommended", "evidence": [ { "id": "A0A3Q2U2N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N2" } ] } ], "protein_names": [ { "name": "Cysteine rich secretory protein 2", "type": "synonym", "evidence": [ { "id": "A0A3Q2U2N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U2N2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC428667", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N2", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U2N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U2N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000053699", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000053699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018244", "database": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U3D2-1", "uniprot_ac": "A0A3Q2U3D2", "uniprot_id": "A0A3Q2U3D2_CHICK", "mass": { "chemical_mass": 139339.0, "monoisotopic_mass": 139339.0 }, "refseq": { "ac": "XP_004940107", "name": "zinc finger protein ZFAT isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940107" }, "gene_names": [ { "name": "ZFAT", "type": "recommended", "evidence": [ { "id": "A0A3Q2U3D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ] }, { "name": "ZFAT", "type": "synonym", "evidence": [ { "id": "XP_004940107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940107" } ] } ], "protein_names": [ { "name": "Zinc finger protein ZFAT", "type": "recommended", "evidence": [ { "id": "A0A3Q2U3D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 406", "type": "synonym", "evidence": [ { "id": "A0A3Q2U3D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein ZFAT isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940107" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940107" } ] }, { "annotation": "May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2#function" }, { "database": "UniProtKB", "id": "ARBA00055129", "url": "https://www.uniprot.org/uniprotkb/ARBA00055129#function" }, { "database": "UniProtKB", "id": "A0A8V0Y1G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFAT", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2", "locus": { "chromosome": "2", "start_pos": 141537959, "end_pos": 141623973, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009345", "url": "https://www.ensembl.org/id/ENSGALG00010009345" } ] } } ], "crossref": [ { "id": "A0A3Q2U3D2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037698", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420319", "url": "https://www.ncbi.nlm.nih.gov/gene/420319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420319", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420319", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEQTTEI", "url": "https://omabrowser.org/oma/group/WEQTTEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3D2", "url": "https://www.orthodb.org/?gene=A0A3Q2U3D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1G8", "url": "https://www.orthodb.org/?gene=A0A8V0Y1G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAAGISSIFMCKLCNLFSPSQSELLSHVSAKHTEEGTNVDDIIIPLQPLTAPTDINRNGEELAVKKKRGRPKGSTKKLCVDEDVAENNSSLNEEAQTGTEEGPEVTEVSPGSLECRKCNRKFSNMRQLRKHICIIVLNEGEEEGDGGNDSDVDLDRKEDEREKTPKRPRVQKTEKTPSTKETEQVPGAKNPIISVVLTAHEAIPGATKIVPVEAAPQESEPTTPETVVQDPSQRRGYQEYAIQQTPYEQTMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSYCNYASAIKANLNVHMRKHTGEKFSCDYCTFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIKETHDLQDKKVKDVFDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDERPFACELCGHGATKYQALELHVRKHPFVYVCSVCLMKFVSSVRLRAHIKEVHADLQETSVFNSSINQSFCLLEPGGDIQPEALGEQLSQTADELTIMSTNPVNTPSTCADESIAADVNHNDQHNGDLKTNTIPSLECENPLVENARETVCEASTDTAVTNIQSCVMSDCFLLKNGTSAPDELKDSAANGEESSHCSSVNEQGEETQLLLTEDASLNVSQNNAVTEDLSGSEEKNQSVASSESETSNPSVLNSTGTTDPLLAPDANAAVSPQAASSNADKSDNRSGAVAFMQILDSLQKRQMNTELCERIRKVYGDLECEYCGKLFWYQVHYDMHVRTHTREHLYYCSQCSYSSITKNCLKRHVIQKHSNILLKCPTEHCDYSTPDKYKLQAHLKVHSELDKKSYSCPVCEKSFSEDRLIKSHIKINHPEVSMSTISEILGRRVQLKGLIGKRAVKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKSTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYVNVGSGEPAAEALIQQGGIKCPVCSFVYGTKWEFNRHLKNKHGMKLVEHDGEAKWELTAEVSEEASTQYVHITEAGEDDQGTQAAVAALQNLRYTSENGERLDPTAVNILQQIIELGSETHDATAVASVVTMAPGTVTVVKQVKEEEQSANHTLMIQETLQQASVELSEQHHLVVSSDEVEGIETVTVYTQGGEASEFIVYVQEAMQSVEEQTVEQSVQEL", "length": 1242, "header": "tr|A0A3Q2U3D2-1|A0A3Q2U3D2_CHICK Isoform 1 of Zinc finger protein ZFAT OS=Gallus gallus OX=9031 GN=ZFAT PE=4 SV=1 CANONICAL=A0A3Q2U3D2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2/entry", "sequence": { "sequence": "MEAAAAGISSIFMCKLCNLFSPSQSELLSHVSAKHTEEGTNVDDIIIPLQPLTAPTDINRNGEELAVKKKRGRPKGSTKKLCVDEDVAENNSSLNEEAQTGTEEGPEVTEVSPGSLECRKCNRKFSNMRQLRKHICIIVLNEGEEEGDGGNDSDVDLDRKEDEREKTPKRPRVQKTEKTPSTKETEQVPGAKNPIISVVLTAHEAIPGATKIVPVEAAPQESEPTTPETVVQDPSQRRGYQEYAIQQTPYEQTMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSYCNYASAIKANLNVHMRKHTGEKFSCDYCTFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIKETHDLQDKKVKDVFDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDERPFACELCGHGATKYQALELHVRKHPFVYVCSVCLMKFVSSVRLRAHIKEVHADLQETSVFNSSINQSFCLLEPGGDIQPEALGEQLSQTADELTIMSTNPVNTPSTCADESIAADVNHNDQHNGDLKTNTIPSLECENPLVENARETVCEASTDTAVTNIQSCVMSDCFLLKNGTSAPDELKDSAANGEESSHCSSVNEQGEETQLLLTEDASLNVSQNNAVTEDLSGSEEKNQSVASSESETSNPSVLNSTGTTDPLLAPDANAAVSPQAASSNADKSDNRSGAVAFMQILDSLQKRQMNTELCERIRKVYGDLECEYCGKLFWYQVHYDMHVRTHTREHLYYCSQCSYSSITKNCLKRHVIQKHSNILLKCPTEHCDYSTPDKYKLQAHLKVHSELDKKSYSCPVCEKSFSEDRLIKSHIKINHPEVSMSTISEILGRRVQLKGLIGKRAVKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKSTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYVNVGSGEPAAEALIQQGGIKCPVCSFVYGTKWEFNRHLKNKHGMKLVEHDGEAKWELTAEVSEEASTQYVHITEAGEDDQGTQAAVAALQNLRYTSENGERLDPTAVNILQQIIELGSETHDATAVASVVTMAPGTVTVVKQVKEEEQSANHTLMIQETLQQASVELSEQHHLVVSSDEVEGIETVTVYTQGGEASEFIVYVQEAMQSVEEQTVEQSVQEL", "length": 1242, "header": "tr|A0A3Q2U3D2-1|A0A3Q2U3D2_CHICK Isoform 1 of Zinc finger protein ZFAT OS=Gallus gallus OX=9031 GN=ZFAT PE=4 SV=1 CANONICAL=A0A3Q2U3D2-1" }, "locus": { "chromosome": "2", "start_pos": 141623904, "end_pos": 141539006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022261.1", "url": "https://www.ensembl.org/id/ENSGALT00010022261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012793.1", "url": "https://www.ensembl.org/id/ENSGALP00010012793.1" } ] } }, { "isoform_ac": "A0A8V0Y1G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1G8/entry", "sequence": { "sequence": "MEAAAAGISSIFMCKLCNLFSPSQSELLSHVSAKHTEEGTNVDDIIIPLQPLTAPTDINRNGEELAVKKKRGRPKGSTKKLCVDEDVAENNSSLNEEAQTGTEEGPEVTEVSPGSLECRKCNRKFSNMRQLRKHICIIVLNEGEEEGDGGATKIVPVEAAPQESEPTTPETVVQDPSQRRGYQEYAIQQTPYEQTMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSYCNYASAIKANLNVHMRKHTGEKFSCDYCTFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIKETHDLQDKKVKDVFDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDERPFACELCGHGATKYQALELHVRKHPFVYVCSVCLMKFVSSVRLRAHIKEVHADLQETSVFNSSINQSFCLLEPGGDIQPEALGEQLSQTADELTIMSTNPVNTPSTCADESIAADVNHNDQHNGDLKTNTIPSLECENPLVENARETVCEASTDTAVTNIQSCVMSDCFLLKNGTSAPDELKDSAANGEESSHCSSVNEQGEETQLLLTEDASLNVSQNNAVTEDLSGSEEKNQSVASSESETSNPSVLNSTGTTDPLLAPDANAAVSPQAASSNADKSDNRSGAVAFMQILDSLQKRQMNTELCERIRKVYGDLECEYCGKLFWYQVHYDMHVRTHTREHLYYCSQCSYSSITKNCLKRHVIQKHSNILLKCPTEHCDYSTPDKYKLQAHLKVHSELDKKSYSCPVCEKSFSEDRLIKSHIKINHPEVSMSTISEILGRRVQLKGLIGKRAVKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKSTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYVNVGSGEPAAEALIQQGGIKCPVCSFVYGTKWEFNRHLKNKHGMKLVEHDGEAKWELTAEVSEEASTQYVHITEAGEDDQGTQAAVAALQNLRYTSENGERLDPTAVNILQQIIELGSETHDATAVASVVTMAPGTVTVVKQVKEEEQSANHTLMIQETLQQASVELSEQHHLVVSSDEVEGIETVTVYTQGGEASEFIVYVQEAMQSVEEQTVEQSVQEL", "length": 1184, "header": "tr|A0A8V0Y1G8-1|A0A3Q2U3D2_CHICK Computationally mapped isoform of Zinc finger protein ZFAT OS=Gallus gallus OX=9031 GN=ZFAT PE=4 SV=1 CANONICAL=A0A3Q2U3D2-1" }, "locus": { "chromosome": "2", "start_pos": 141623904, "end_pos": 141539006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022265.1", "url": "https://www.ensembl.org/id/ENSGALT00010022265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012798.1", "url": "https://www.ensembl.org/id/ENSGALP00010012798.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420319", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420319", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A2U0-1", "protein_name": "Zinc finger protein ZFAT", "gene_name": "Zfat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METRAAENTAIFMCKCCNLFSPNQSELVTHVSEKHGEEGVNVDDVIIPLRPLNTPENPNPSKGGDEFLVMKRKRGRPKGSTKKPSTEEEVVENLVSPIEDGPLAPEEGSRLAPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEGDAGLEMIQEPGNESDLDLEKTYKEDDREKTSKRPRAQKTEKVQKISGKEAGQLSGAKKPIISVVLTAHEAIPGATKIIPVEAGPPETGAPPPETTAADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDMHDPQDKKVKEALDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCAICLKKFVSSIRLRSHIREVHGAAQETLVFTSSINQSFCLLEPGGDIQQEALGNQLPLAAEEFVCPEIDVRKGEVCPGEAQPEVGLRELEAPGEACAPAVPLANPQSVSVSLSPCKLETTVVNSDLNSLGVVSDDFLLKTDTSSAEPHAAAELTSDTQHRGSAQTQGEEVTLLLAKAKSTGPDSESPPSGGQNVGALPASESDSNRCLRANPAETSDLLPTVADGGDLGVCQPDSCTSSSEHHPGSTAFMKVLDSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTELDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMNTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTSDGKQFKCTVCDYTAAQKPQLLRHMEQHASFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGSGELAAEALIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWEPATETPEEPSTQYLYITEAEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGSETHDAAAVASVVAMAPGTVTVVKQVTDEEPNSNHTVMIQETLQQASVELAEQHHLVVSSDDVEGIETVTVYTQGGEASEFIVYVQEAVQPMEEQVGEQPAPEL", "length": 1243 }, "evidence": [ { "id": "A0A3Q2U3D2", "url": "https://omabrowser.org/oma/group/A0A3Q2U3D2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TS63-1", "protein_name": "Zinc finger protein ZFAT", "gene_name": "Zfat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METRTAENTAIFMCKCCNLFSPNQSELVTHVSEKHGEEGVNVDDVIIPLRPLNTPENPNPSKGGDEFLVMKRKRGRPKGSTKKPSTEEEVVENLVSPSEDGPLATEEGSRLAPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEDGDAGNESDLDLEKTYKEDDREKASKRPRAQKTEKVQKISGKEAGQLSGAKKPIISVVLTAHEAIPGATKIIPVEAGPPETGAPPPETTAADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCSQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDMHDPQDKKVKEALDELRLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCALCLKKFVSSIRLRSHIREVHGAAQETLVFTSSINQSFCLLEPGGDIQQEALGDQLQLAAEEFVCPEIDVRKEEACPGEAQPEVGLRELVVPGDAHAPPPGPLATPQSESSSLSPCKLETTVVSSDLNSLGVVSDDFLLKSDTSSAEPPAAAEATSDTQHRDSAQTQGEEVTLLLAKAKSAGPDPESSPGGRQKVGALPASESDSSTCLRANPTEASDLLPTVTDGGDLGVCQPDSCTPSSEHHPGSTAFMKVLDSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTELDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMNTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTSDGKQFKCTVCDYTAAQKPQLLRHMEQHASFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYTNVGSGELAAEALIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWEPAAETPEEPSTQYLYITEAEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGSETHDAAAVASVVAMAPGTVTVVKQVTDEEPSSNHTVMIQETLQQASVELAEQHHLVVSSDDVEGIETVTVYTQGGEASEFIVYVQEAVQPVEEQVGEQPAPEL", "length": 1237 }, "evidence": [ { "id": "A0A3Q2U3D2", "url": "https://omabrowser.org/oma/group/A0A3Q2U3D2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P243-1", "protein_name": "Zinc finger protein ZFAT", "gene_name": "ZFAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1243 }, "evidence": [ { "id": "A0A3Q2U3D2", "url": "https://omabrowser.org/oma/group/A0A3Q2U3D2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3D2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3D2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U3N0-1", "uniprot_ac": "A0A3Q2U3N0", "uniprot_id": "A0A3Q2U3N0_CHICK", "mass": { "chemical_mass": 59074.0, "monoisotopic_mass": 59074.0 }, "refseq": {}, "gene_names": [ { "name": "MFSD13A", "type": "recommended", "evidence": [ { "id": "A0A3Q2U3N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily domain containing 13A", "type": "synonym", "evidence": [ { "id": "A0A3Q2U3N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3N0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD13A", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0", "locus": { "chromosome": "6", "start_pos": 23953969, "end_pos": 23941029, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018532", "url": "https://www.ensembl.org/id/ENSGALG00010018532" } ] } } ], "crossref": [ { "id": "A0A3Q2U3N0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008039", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008039", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423861", "url": "https://www.ncbi.nlm.nih.gov/gene/423861", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423861", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423861", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNSVNDP", "url": "https://omabrowser.org/oma/group/WNSVNDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3N0", "url": "https://www.orthodb.org/?gene=A0A3Q2U3N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28658:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28658:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3N0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELNADPINMGLRLLACLFHLPTAVIYGSLSLFVSILHNVFLLYYVDTFVSVYKIDKLSFWIGETVFLIWNSLNDPLFGWLSDRVFLSTQQPGAEISSPEVVLKRLRALSHNGPLFAISFLAFWVAWAHPGLQFLLCLCMYDSFLTMVDLHHNALLADLAVSAKDRTSLNFYCSFFSAIGSLSVFMSYAVWNKEDFFSFRIFCIVLAFCSIVGFTLSTQLLRQRFETDGKAKWDQESTLKELYIEKLSVPQEKRITLVEYLQQLSRHRNFLWFVCMNLIQVFHCHFNSNFFPLFLEHLLSDKISVSTGSFLLGISYIAPHLNNLYFLSLCRRWGVYAVVRGLFFLKLALSVVMLLAGPDQVYLLCIFIASNRVFTEGTCKLLNLVVTDLVDEDLVLNRRKQAASALLFGMVALVTKPGQTFAPLIGTWLLCVYTGYDIFQRNPLSNVVSAQPKLESDTILEPTLRQGCFYLLVFVPITCALLQLLSWTQFSLHGKRLQMVKAQRQGLMQGRAPEIKMI", "length": 518, "header": "tr|A0A3Q2U3N0-1|A0A3Q2U3N0_CHICK Isoform 1 of Major facilitator superfamily domain containing 13A OS=Gallus gallus OX=9031 GN=MFSD13A PE=4 SV=1 CANONICAL=A0A3Q2U3N0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0/entry", "sequence": { "sequence": "MELNADPINMGLRLLACLFHLPTAVIYGSLSLFVSILHNVFLLYYVDTFVSVYKIDKLSFWIGETVFLIWNSLNDPLFGWLSDRVFLSTQQPGAEISSPEVVLKRLRALSHNGPLFAISFLAFWVAWAHPGLQFLLCLCMYDSFLTMVDLHHNALLADLAVSAKDRTSLNFYCSFFSAIGSLSVFMSYAVWNKEDFFSFRIFCIVLAFCSIVGFTLSTQLLRQRFETDGKAKWDQESTLKELYIEKLSVPQEKRITLVEYLQQLSRHRNFLWFVCMNLIQVFHCHFNSNFFPLFLEHLLSDKISVSTGSFLLGISYIAPHLNNLYFLSLCRRWGVYAVVRGLFFLKLALSVVMLLAGPDQVYLLCIFIASNRVFTEGTCKLLNLVVTDLVDEDLVLNRRKQAASALLFGMVALVTKPGQTFAPLIGTWLLCVYTGYDIFQRNPLSNVVSAQPKLESDTILEPTLRQGCFYLLVFVPITCALLQLLSWTQFSLHGKRLQMVKAQRQGLMQGRAPEIKMI", "length": 518, "header": "tr|A0A3Q2U3N0-1|A0A3Q2U3N0_CHICK Isoform 1 of Major facilitator superfamily domain containing 13A OS=Gallus gallus OX=9031 GN=MFSD13A PE=4 SV=1 CANONICAL=A0A3Q2U3N0-1" }, "locus": { "chromosome": "6", "start_pos": 23952492, "end_pos": 23946632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044837.1", "url": "https://www.ensembl.org/id/ENSGALT00010044837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026759.1", "url": "https://www.ensembl.org/id/ENSGALP00010026759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423861", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423861", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TUM7-1", "protein_name": "Major facilitator superfamily domain containing 13A", "gene_name": "MFSD13A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELGGPWAWLLGLPTAVVYGSLALFVSVLHNVFLLYYVDTFVSVYKINKAAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPWSGAGLSSRAVVLARVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVALAACSGLGFVGATRLLRRRVEAAGREPGCPSLAVDGGLGEEELLVGGKEAGSITLSQYLRQLARHRNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHPGLLCLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQPPLTPVGSAQPWPEPPAPPPAQAPALRQGCFYLLVLVPITCALLQLFTWSQFTLHGRRLHMVKAQRQNLARAQTLDVKTV", "length": 517 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0KYP0-1", "protein_name": "Major facilitator superfamily domain containing 13A", "gene_name": "Slc68a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARTSRRRGTTSLGLRHPAAGRPTRVAWRRRGPGPYHGSSGVLAAPCSGPPAGCRSCGSGWVAAAEGRAGSSSAALGGLAASSFLQMGVSLFSSFSPCLPMKSRDEDGRSGNGAEAPPAAMGLDWPPAWLLGLPTAVVYGSLAFFTTILHNVFLLYYVDTFVSVYKINKVSFWVGETVFLLWNSFNDPLFGWLSDRRFLSSQPRSGAGLSSRDVVLTRVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGAMSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGATQLLKRRIEATRKDRGCPGLVMDGGVCEEEPLVGGEEAGSITLGQYLRQLAHHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLLLLKLSLSLLMLLAGPDHPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQPPVTSVGSVQPWPEPPAPAPVQAPTLRQGCFYLLVLVPIICALLQLFTWSQFTLHGRRLRMVKAQRQNLAQIHTLNIKMV", "length": 637 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HXW7-1", "protein_name": "Transmembrane protein 180", "gene_name": "Mfsd13a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLDWPQAWLLGLPTAVVYGSLALFTSILHNVFLLYYVDTFVSVYKINKMSFWIGETVFLLWNSFNDPLFGWLSDRQFLSSQSRSGAGLSSRDVVLTRVRALSWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSMSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGATQLLRRRIEATRRDKGCPALVVDGGVCEEELLVGGEEAGSITLGQYLRQLARHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDRPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQPPVTTVGSVQPWPEPPAPAPAQAPTLRQGCFYLLVLVSISCALLQLFTWSRFTLHGRRLRVVKAQRQNLAQIHTLDIKTV", "length": 517 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q14CX5-1", "protein_name": "Solute carrier family 68 member 1", "gene_name": "SLC68A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLGQPQAWLLGLPTAVVYGSLALFTTILHNVFLLYYVDTFVSVYKINKMAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLSSRAVVLARVQALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVTLAVSSGLGFLGATQLLRRRVEAARKDPGCSGLVVDSGLCGEELLVGSEEADSITLGRYLRQLARHRNFLWFVSMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSILLGLSYVAPHLNNLYFLSLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHLSLLCLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQSLITPVGSAHPWPEPPAPAPAQAPTLRQGCFYLLVLVPITCALLQLFTWSQFTLHGRRLHMVKAQRQNLSQAQTLDVKMV", "length": 517 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q58CT4-1", "protein_name": "Solute carrier family 68 member 1", "gene_name": "SLC68A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLGGPWAWLLGLPTAVVYGSLALFVSVLHNVFLLYYVDTFVSVYKIDKAAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLSSRAVVLARVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCLALATGSGLGFVGAARLLRRRVEAAGREPGCPAMAVNDGLCEEELLVGGEEAGSITLGQYLQQLARHRNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHPGLLCLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQHPPAPVGSAQPWPEPPAPPPAQAPPLRQGCFYLLVLVPIACALLQLFTWSQFTLHGRRLHMVKAQRQSLSRAQTLDVKMV", "length": 517 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PDE8-1", "protein_name": "Solute carrier family 68 member 1", "gene_name": "Slc68a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLDWPQAWLLGLPIAVVYGSLALFTSILHNVFLLYYVDTFVSVYKINKVSFWVGETVFLLWNSFNDPLFGWLSDRQLLSSQPRSGAGLSSRDVVLTRVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSSHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGTTQLLKRQIEATRRDRGCPGLDLDGGVCEEEPPVGGEEAGNITLGQYLRQLARHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLSLSLLMLLAGPDHPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQSPMTPVGSVRPWPELPAPAPAPAQAPTLRQGCFYLLVFVPITCALLQLFTWSQFTLHGRRLRTVKAQRQNLAQIHTLNIKMV", "length": 519 }, "evidence": [ { "id": "A0A3Q2U3N0", "url": "https://omabrowser.org/oma/group/A0A3Q2U3N0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3N0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U3N0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 518, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U3N0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3N0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U3Q9-1", "uniprot_ac": "A0A3Q2U3Q9", "uniprot_id": "A0A3Q2U3Q9_CHICK", "mass": { "chemical_mass": 20564.0, "monoisotopic_mass": 20564.0 }, "refseq": { "ac": "XP_024999423", "name": "protein Flattop", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999423" }, "gene_names": [ { "name": "CFAP126", "type": "recommended", "evidence": [ { "id": "A0A3Q2U3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9" } ] }, { "name": "CFAP126", "type": "synonym", "evidence": [ { "id": "XP_024999423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999423" } ] } ], "protein_names": [ { "name": "Protein Flattop", "type": "recommended", "evidence": [ { "id": "A0A3Q2U3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9/entry#names_and_taxonomy" } ] }, { "name": "Cilia- and flagella-associated protein 126", "type": "synonym", "evidence": [ { "id": "A0A3Q2U3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9/entry#names_and_taxonomy" } ] }, { "name": "protein Flattop", "type": "synonym", "evidence": [ { "id": "XP_024999423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999423" } ] }, { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9#function" }, { "database": "UniProtKB", "id": "ARBA00045261", "url": "https://www.uniprot.org/uniprotkb/ARBA00045261#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP126", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9", "locus": { "chromosome": "25", "start_pos": 2471722, "end_pos": 2469520, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027446", "url": "https://www.ensembl.org/id/ENSGALG00010027446" } ] } } ], "crossref": [ { "id": "A0A3Q2U3Q9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3Q9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038231", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038231", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23705", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23705", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859681", "url": "https://www.ncbi.nlm.nih.gov/gene/100859681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859681", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTMIRAP", "url": "https://omabrowser.org/oma/group/HTMIRAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3Q9", "url": "https://www.orthodb.org/?gene=A0A3Q2U3Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34639:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34639:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARYGAGQYEDAFSAPRLQNWSVARHCRRRPSPRDGSTQPLANDRGHLLPSVRRSQVSPWGTFVGTWEMPARIPPPKLNLTARSAAAAAQLCGWIRTPTALSTACNGGGTVICGQPQESCRALSATAEPRSGNEDTRGAQPSPTAALEEQWGSDAVGQNAARGEPRGRGGAKAHPEGAAPSEGTERNPAERSQS", "length": 195, "header": "tr|A0A3Q2U3Q9-1|A0A3Q2U3Q9_CHICK Isoform 1 of Protein Flattop OS=Gallus gallus OX=9031 GN=CFAP126 PE=3 SV=1 CANONICAL=A0A3Q2U3Q9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9/entry", "sequence": { "sequence": "MAARYGAGQYEDAFSAPRLQNWSVARHCRRRPSPRDGSTQPLANDRGHLLPSVRRSQVSPWGTFVGTWEMPARIPPPKLNLTARSAAAAAQLCGWIRTPTALSTACNGGGTVICGQPQESCRALSATAEPRSGNEDTRGAQPSPTAALEEQWGSDAVGQNAARGEPRGRGGAKAHPEGAAPSEGTERNPAERSQS", "length": 195, "header": "tr|A0A3Q2U3Q9-1|A0A3Q2U3Q9_CHICK Isoform 1 of Protein Flattop OS=Gallus gallus OX=9031 GN=CFAP126 PE=3 SV=1 CANONICAL=A0A3Q2U3Q9-1" }, "locus": { "chromosome": "25", "start_pos": 2471660, "end_pos": 2469533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066531.1", "url": "https://www.ensembl.org/id/ENSGALT00010066531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040755.1", "url": "https://www.ensembl.org/id/ENSGALP00010040755.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859681", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859681", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U3Q9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U3Q9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 195, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U3Q9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U3Q9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 145 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { 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50194.0, "monoisotopic_mass": 50194.0 }, "refseq": { "ac": "NP_001376250", "name": "RUN domain-containing protein 3B isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" }, "gene_names": [ { "name": "RUNDC3B", "type": "recommended", "evidence": [ { "id": "A0A3Q2U409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409" } ] }, { "name": "RUNDC3B", "type": "synonym", "evidence": [ { "id": "NP_001376250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 3B", "type": "recommended", "evidence": [ { "id": "A0A3Q2U409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 3B isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001376250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" } ] }, { "name": "RUN domain-containing protein 3B", "type": "synonym", "evidence": [ { "id": "NP_001376250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" } ] }, { "name": "Rap2-binding protein 9", "type": "synonym", "evidence": [ { "id": "NP_001376250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01076098.1, SRR13267654.257864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000036.1. On Dec 11, 2020 this sequence version replaced XP_015136876.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U409", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUNDC3B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409", "locus": { "chromosome": "2", "start_pos": 20720751, "end_pos": 20675562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004226", "url": "https://www.ensembl.org/id/ENSGALG00010004226" } ] } } ], "crossref": [ { "id": "A0A3Q2U409", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U409", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008954", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420535", "url": "https://www.ncbi.nlm.nih.gov/gene/420535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KQWYDKS", "url": "https://omabrowser.org/oma/group/KQWYDKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U409", "url": "https://www.orthodb.org/?gene=A0A3Q2U409", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UB46", "url": "https://www.orthodb.org/?gene=A0A3Q2UB46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGC3", "url": "https://www.orthodb.org/?gene=A0A8V0XGC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJ15", "url": "https://www.orthodb.org/?gene=A0A8V0XJ15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U409", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U409-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB46", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLGLGGLGASARRKSVPSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQITWFGYESTRSFWDYIRVACRKVSHNCICSIENMENVGSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGKGLDGTFPAVIDYTPYLKFIQSSDSISSDEEELRTVGSSGSEGSTPENIVPPVIVDENIWYNKCKRVEQKYRLALEQKGYLEELVRLRENQLSESVSQNKLLLQRIEDMDLAHKMEKEQLEYIIMELQDQLTVLKNNDLRSRQELTTHLTNQWPSPGALDVNAVALDTLLYRKHNQQWDEKSFQSLDQLSADVSLSQTSLDPGHSQDGKQDGINLLNEGKEDTPSLLGLCGSLTSVASYKSLTSLKSSEYLASPTTEMTSPGLTPS", "length": 448, "header": "tr|A0A3Q2U409-1|A0A3Q2U409_CHICK Isoform 1 of RUN domain-containing protein 3B OS=Gallus gallus OX=9031 GN=RUNDC3B PE=3 SV=1 CANONICAL=A0A3Q2U409-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U409-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409/entry", "sequence": { "sequence": "MASLGLGGLGASARRKSVPSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQITWFGYESTRSFWDYIRVACRKVSHNCICSIENMENVGSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGKGLDGTFPAVIDYTPYLKFIQSSDSISSDEEELRTVGSSGSEGSTPENIVPPVIVDENIWYNKCKRVEQKYRLALEQKGYLEELVRLRENQLSESVSQNKLLLQRIEDMDLAHKMEKEQLEYIIMELQDQLTVLKNNDLRSRQELTTHLTNQWPSPGALDVNAVALDTLLYRKHNQQWDEKSFQSLDQLSADVSLSQTSLDPGHSQDGKQDGINLLNEGKEDTPSLLGLCGSLTSVASYKSLTSLKSSEYLASPTTEMTSPGLTPS", "length": 448, "header": "tr|A0A3Q2U409-1|A0A3Q2U409_CHICK Isoform 1 of RUN domain-containing protein 3B OS=Gallus gallus OX=9031 GN=RUNDC3B PE=3 SV=1 CANONICAL=A0A3Q2U409-1" }, "locus": { "chromosome": "2", "start_pos": 20718339, "end_pos": 20675781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009884.1", "url": "https://www.ensembl.org/id/ENSGALT00010009884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005767.1", "url": "https://www.ensembl.org/id/ENSGALP00010005767.1" } ] } }, { "isoform_ac": "A0A3Q2UB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB46/entry", "sequence": { "sequence": "MASLGLGGLGASARRKSVPSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQITWFGYESTRSFWDYIRVACRKVSHNCICSIENMENVGSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGKGLDGTFPAVIDYTPYLKFIQSSDSISSDEEELRTVGSSGSEGSTPENIVPPVIVDENIWYNKCKRVEQKYRLALEQKGYLEELVRLRENQLSESVSQNKLLLQRIEDMDLAHKMEKEQLEYIIMELQDQFGCH", "length": 316, "header": "tr|A0A3Q2UB46-1|A0A3Q2UB46_CHICK Computationally mapped isoform of RUN domain-containing protein 3B OS=Gallus gallus OX=9031 GN=RUNDC3B PE=3 SV=1 CANONICAL=A0A3Q2U409-1" }, "locus": { "chromosome": "2", "start_pos": 20709355, "end_pos": 20675781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009879.1", "url": "https://www.ensembl.org/id/ENSGALT00010009879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005762.1", "url": "https://www.ensembl.org/id/ENSGALP00010005762.1" } ] } }, { "isoform_ac": "A0A8V0XGC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGC3/entry", "sequence": { "sequence": "MASLGLGGLGASARRKSVPSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQITWFGYESTRSFWDYIRVACRKVSHNCICSIENMENVGSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGKGLDGTFPAVIDYTPYLKFIQSSDSISSDEEELRTVGSSGSEGSTPENIVPPVIVDENIWYNKCKRVEQKYRLALEQKGYLEELVRLRENQLSESVSQNKLLLQRIEDMDLAHKMEKEQLEYIIMELQDQLGADREQVLFRVRWEPEDREFPFGLKV", "length": 339, "header": "tr|A0A8V0XGC3-1|A0A3Q2U409_CHICK Computationally mapped isoform of RUN domain-containing protein 3B OS=Gallus gallus OX=9031 GN=RUNDC3B PE=3 SV=1 CANONICAL=A0A3Q2U409-1" }, "locus": { "chromosome": "2", "start_pos": 20706460, "end_pos": 20675781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009878.1", "url": "https://www.ensembl.org/id/ENSGALT00010009878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005761.1", "url": "https://www.ensembl.org/id/ENSGALP00010005761.1" } ] } }, { "isoform_ac": "A0A8V0XJ15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ15/entry", "sequence": { "sequence": "MASLGLGGLGASARRKSVPSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQITWFGYESTRSFWDYIRVACRKVSHNCICSIENMENVGSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGKGLDGTFPAVIDYTPYLKFIQSSDSISSDEEELRTVGSSGSEGSTPENIVPPVIVDENIWYNKCKRVEQKYRLALEQKGYLEELVRLRENQLSESVSQNKLLLQRIEDMDLAHKMEKEQLEYIIMELQDQLEVLPFFIDASWHCLKIRLNGKLTLR", "length": 338, "header": "tr|A0A8V0XJ15-1|A0A3Q2U409_CHICK Computationally mapped isoform of RUN domain-containing protein 3B OS=Gallus gallus OX=9031 GN=RUNDC3B PE=3 SV=1 CANONICAL=A0A3Q2U409-1" }, "locus": { "chromosome": "2", "start_pos": 20701486, "end_pos": 20675781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009876.1", "url": "https://www.ensembl.org/id/ENSGALT00010009876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005759.1", "url": "https://www.ensembl.org/id/ENSGALP00010005759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5J4-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "RUNDC3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASLSLGGLGGSRGAGGSGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGGLDGNFPAVIDYTPYLKFTQSSDSISSDEEELRTLGSSGSESSTPENVGPPFIMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSCQSLDQLSAEVSLSQSSLDPGQSQEGDGKQDTLSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS", "length": 402 }, "evidence": [ { "id": "A0A3Q2U409", "url": "https://omabrowser.org/oma/group/A0A3Q2U409/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08E29-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "RUNDC3B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRSLGGLGGSRGGGGGVKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKESSQSCRWLSHLQIPLQGQVTWFGYGSPRSFWDYIRVACRKVSQNCICSIENMEHVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGERLDGNLPAVIDYIPYLRFTQSSDSISSDEEELRTLGSSDSESSTPEKAGPPVIMDENSWFNKCKRVKQKYQLTLEQKGYLEELLQLRENQLSESVAQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNLISEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS", "length": 423 }, "evidence": [ { "id": "A0A3Q2U409", "url": "https://omabrowser.org/oma/group/A0A3Q2U409/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3B7K9-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "Rundc3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRSLGGLSGSRGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEEGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSEGSTPENVGPPLILDENSWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPGHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTEITSPGLTPS", "length": 403 }, "evidence": [ { "id": "A0A3Q2U409", "url": "https://omabrowser.org/oma/group/A0A3Q2U409/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PDC0-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "Rundc3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRSLGGLSGSRGGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSESSTPENVGPPLILDENTWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPSHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTELTSPGLTPS", "length": 408 }, "evidence": [ { "id": "A0A3Q2U409", "url": "https://omabrowser.org/oma/group/A0A3Q2U409/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NL0-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "RUNDC3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS", "length": 473 }, "evidence": [ { "id": "A0A3Q2U409", "url": "https://omabrowser.org/oma/group/A0A3Q2U409/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U409-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 448, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U409-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U409" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U409" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 183, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U419-1", "uniprot_ac": "A0A3Q2U419", "uniprot_id": "A0A3Q2U419_CHICK", "mass": { "chemical_mass": 36820.0, "monoisotopic_mass": 36820.0 }, "refseq": { "ac": "XP_015135781", "name": "methylglutaconyl-CoA hydratase, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135781" }, "gene_names": [ { "name": "AUH", "type": "recommended", "evidence": [ { "id": "A0A3Q2U419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ] }, { "name": "AUH", "type": "synonym", "evidence": [ { "id": "XP_015135781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135781" } ] } ], "protein_names": [ { "name": "AU RNA binding methylglutaconyl-CoA hydratase", "type": "synonym", "evidence": [ { "id": "A0A3Q2U419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419/entry#names_and_taxonomy" } ] }, { "name": "methylglutaconyl-CoA hydratase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135781" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135781" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AUH", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419", "locus": { "chromosome": "Z", "start_pos": 44819604, "end_pos": 44932335, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009396", "url": "https://www.ensembl.org/id/ENSGALG00010009396" } ] } } ], "crossref": [ { "id": "A0A3Q2U419", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U419", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021843", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021843", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427269", "url": "https://www.ncbi.nlm.nih.gov/gene/427269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YEQAHAW", "url": "https://omabrowser.org/oma/group/YEQAHAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U419", "url": "https://www.orthodb.org/?gene=A0A3Q2U419", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXB9", "url": "https://www.orthodb.org/?gene=A0A8V0XXB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XXC4", "url": "https://www.orthodb.org/?gene=A0A8V0XXC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1T8", "url": "https://www.orthodb.org/?gene=A0A8V0Y1T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5V0", "url": "https://www.orthodb.org/?gene=A0A8V0Y5V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5V4", "url": "https://www.orthodb.org/?gene=A0A8V0Y5V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5V9", "url": "https://www.orthodb.org/?gene=A0A8V0Y5V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAD4", "url": "https://www.orthodb.org/?gene=A0A8V0YAD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAD9", "url": "https://www.orthodb.org/?gene=A0A8V0YAD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTQ9", "url": "https://www.orthodb.org/?gene=E1BTQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941:SF12", "database": "PANTHER", "categories": [ "Protein 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}, { "id": "A0A8V0XXC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTQ9", "url": "https://www.uniprot.org/uniprotkb/E1BTQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGEGGNKTRIEKAPEAKLNIRGSARGGTQRLPRAIGVSLAKELIFSARIVDGEEAKSIGLISHVVEQNEAGDAAYRRALALAREFLPQGPVAMRVAKLAIDQGMEVDLVTGLAIEEACYAQTIPTKDRIEGLLAFKEKRSPRYKGE", "length": 350, "header": "tr|A0A3Q2U419-1|A0A3Q2U419_CHICK Isoform 1 of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U419-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGEGGNKTRIEKAPEAKLNIRGSARGGTQRLPRAIGVSLAKELIFSARIVDGEEAKSIGLISHVVEQNEAGDAAYRRALALAREFLPQGPVAMRVAKLAIDQGMEVDLVTGLAIEEACYAQTIPTKDRIEGLLAFKEKRSPRYKGE", "length": 350, "header": "tr|A0A3Q2U419-1|A0A3Q2U419_CHICK Isoform 1 of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44822692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022450.1", "url": "https://www.ensembl.org/id/ENSGALT00010022450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012926.1", "url": "https://www.ensembl.org/id/ENSGALP00010012926.1" } ] } }, { "isoform_ac": "A0A8V0XXB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB9/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAERTVES", "length": 211, "header": "tr|A0A8V0XXB9-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44873516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022435.1", "url": "https://www.ensembl.org/id/ENSGALT00010022435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012917.1", "url": "https://www.ensembl.org/id/ENSGALP00010012917.1" } ] } }, { "isoform_ac": "A0A8V0XXC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXC4/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGEGGNKTRIEKAPEAKLNIRGSARGLSEELLKSLLKCPGSSKMLLNCYGFRRALPLSRWIVAQAGSKDLHVKVP", "length": 250, "header": "tr|A0A8V0XXC4-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44834943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022443.1", "url": "https://www.ensembl.org/id/ENSGALT00010022443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012922.1", "url": "https://www.ensembl.org/id/ENSGALP00010012922.1" } ] } }, { "isoform_ac": "A0A8V0Y1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1T8/entry", "sequence": { "sequence": "QLGPPIFLPPQSGTPTSTIHKDERDAQRLLFSSQVPSLPHPHDYCTCPETVTPPFPCASPLLRRKRPNTQPQYRTPNFSALEASLLLQAPQLRSVSGAPQTHTAETRHPDASTSALNHAKPRNTERGTQSSRLGSGRGAGVGGVPCVAPLVTWVRERGWRLMSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGEDELRRGI", "length": 296, "header": "tr|A0A8V0Y1T8-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44932136, "end_pos": 44901708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022434.1", "url": "https://www.ensembl.org/id/ENSGALT00010022434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012916.1", "url": "https://www.ensembl.org/id/ENSGALP00010012916.1" } ] } }, { "isoform_ac": "A0A8V0Y5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V0/entry", "sequence": { "sequence": "QLGPPIFLPPQSGTPTSTIHKDERDAQRLLFSSQVPSLPHPHDYCTCPETVTPPFPCASPLLRRKRPNTQPQYRTPNFSALEASLLLQAPQLRSVSGAPQTHTAETRHPDASTSALNHAKPRNTERGTQSSRLGSGRGAGVGGVPCVAPLVTWVRERGWRLMSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGCN", "length": 290, "header": "tr|A0A8V0Y5V0-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44932136, "end_pos": 44905510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022433.1", "url": "https://www.ensembl.org/id/ENSGALT00010022433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012915.1", "url": "https://www.ensembl.org/id/ENSGALP00010012915.1" } ] } }, { "isoform_ac": "A0A8V0Y5V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V4/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAAYALGCWPWISTSARALLTLSNWPDIPVLLNIFYLVSPPHKYELASPTVNGTGHFSWLSF", "length": 265, "header": "tr|A0A8V0Y5V4-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44839241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022438.1", "url": "https://www.ensembl.org/id/ENSGALT00010022438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012920.1", "url": "https://www.ensembl.org/id/ENSGALP00010012920.1" } ] } }, { "isoform_ac": "A0A8V0Y5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5V9/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMGGTQRLPRAIGVSLAKELIFSARIVDGEEAKSIGLISHVVEQNEAGDAAYRRALALAREFLPQGPVAMRVAKLAIDQGMEVDLVTGLAIEEACYAQTIPTKDRIEGLLAFKEKRSPRYKGE", "length": 276, "header": "tr|A0A8V0Y5V9-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44822692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022448.1", "url": "https://www.ensembl.org/id/ENSGALT00010022448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012925.1", "url": "https://www.ensembl.org/id/ENSGALP00010012925.1" } ] } }, { "isoform_ac": "A0A8V0YAD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD4/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGPCSLQASSTSGQHEKLICPYLKADVSLLYSKHRLATTETLVSYQHYCHSKSKTAPYQLLARKLTLFQLKRGK", "length": 278, "header": "tr|A0A8V0YAD4-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44866094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022436.1", "url": "https://www.ensembl.org/id/ENSGALT00010022436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012918.1", "url": "https://www.ensembl.org/id/ENSGALP00010012918.1" } ] } }, { "isoform_ac": "A0A8V0YAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD9/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGLSEELLKSLLKCPGSSKMLLNCYGFRRALPLSRWIVAQAGSKDLHVKVP", "length": 226, "header": "tr|A0A8V0YAD9-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=1 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44834943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022444.1", "url": "https://www.ensembl.org/id/ENSGALT00010022444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012923.1", "url": "https://www.ensembl.org/id/ENSGALP00010012923.1" } ] } }, { "isoform_ac": "E1BTQ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTQ9/entry", "sequence": { "sequence": "MSAGSSMAAALGGLGLLHGRFRLAAAAAATSSALSPRAPVRGGAATFPSAGRNYGSEAKEEEELRVQYLDEEHKGIVVLGLNRSHAKNALNKNLLKMMSKAVDALKSDKKVRTVIFRSEVPGIFCAGADLKERAKMHSSEVGSFVSKARATINEMANLPVPTIAAIDGIALGGGLELALACDIRVAASSAKMGLVETKLAIIPGAGGTQRLPRAIGVSLAKELIFSARIVDGEEAKSIGLISHVVEQNEAGDAAYRRALALAREFLPQGPVAMRVAKLAIDQGMEVDLVTGLAIEEACYAQTIPTKDRIEGLLAFKEKRSPRYKGE", "length": 326, "header": "tr|E1BTQ9-1|A0A3Q2U419_CHICK Computationally mapped isoform of AU RNA binding methylglutaconyl-CoA hydratase OS=Gallus gallus OX=9031 GN=AUH PE=1 SV=2 CANONICAL=A0A3Q2U419-1" }, "locus": { "chromosome": "Z", "start_pos": 44931653, "end_pos": 44822692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022456.1", "url": "https://www.ensembl.org/id/ENSGALT00010022456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012930.1", "url": "https://www.ensembl.org/id/ENSGALP00010012930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z934-1", "protein_name": "Methylglutaconyl-CoA hydratase, mitochondrial", "gene_name": "Dmel\\CG8778", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSMLIKRASGLARQLARPLVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE", "length": 299 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1LU71-1", "protein_name": "Methylglutaconyl-CoA hydratase, mitochondrial", "gene_name": "Auh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAPGALGALSAGRVRLVAACCARLGSAAWARGTAPRRGYSSEVKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE", "length": 315 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RDX1-1", "protein_name": "4.2.1.18", "gene_name": "auh", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAIVRCRALFQLCRSQINISNGVYRSDSVLQTCLPKRLPCVHRAFSGGVRLYSSEVNSGDDLIVRYLDGDDSGIVVMGINRPEAKNAISKNLVSMMSEALESMKTDNTVRTVILCSMVPGIFCAGADLKERAKMQQSEVGPFVTKARTLISELGALPMPTIAAIDGAALGGGLEMALACDIRVAANSAKMGLVETKLAIIPGAGGTQRLPRTVGVSIAKELIFAARVLNGEEAKSLGLVNHAVEQNKGGDAAYLRALDLAREFIPQGPIAVRMAKLAINQGIEVDLKTGLAIEEACYSQVIPTKDRLEGLLAFKEKRPPRFKGE", "length": 325 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RN10-1", "protein_name": "AU RNA binding methylglutaconyl-CoA hydratase", "gene_name": "AUH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAGVPGALGTLRAGRARLVAAYCAGIGPGWRLPGSWTGLPVGPAIWARGWTPAAGGAAWRRGYSSEAKTEDELRVRYLEEENRGIVVLGINRAYAKNSLSKNLVKMLSKAVDALKSDKKVRTIIVRSEVPGIFCAGADLKERVKMHSSEVGPFVSKLRAVINEIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAIRVAKLAINQGMEVDLVTGLAIEEACYAQTVPTKDRLEGLLAFKEKRTPRYKGE", "length": 338 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JML5-1", "protein_name": "Probable enoyl-CoA hydratase 2, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSFVKYLRRDNLLQLAGKPSLSRNYILQTCRTLIIETSPPEFVKLNRLSGSDSGIIEVNLDRPVTKNAINKEMLKSLQNAFESIHQDNSARVVMIRSLVPGVFCAGADLKERRTMSPSEVHTYVNSLRYMFSFIEALSIPTIAAIEGAALGGGLEMALACDLRICGENAVFGLPETGLAIIPGAGGTQRLSRLVGRSVSKELIFTGRKIDAIEAANKGLVNICVTAGEAHEKAIEMAQQINEKGPLAIKMAKKAIDEGIETNMASGLEVEEMCYQKLLNTQDRLEGLAAFAEKRKPLYTGN", "length": 301 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q13825-1", "protein_name": "Methylglutaconyl-CoA hydratase, mitochondrial", "gene_name": "AUH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE", "length": 339 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54HG7-1", "protein_name": "Methylglutaconyl-CoA hydratase, mitochondrial", "gene_name": "auh", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKHLIKNVSNSVKYNNVTSNNILFSTSSSLKFGRKFTTETQQECILERLEGENKGISVISFNRGHVKNALGKNLMNQFRSHLNELRFCPDTRVVIVRSLVDGVFCSGADLKERALMSQVEASQFVHSLRSSFTELETLQMPTIAAIEGVAVGGGTEMVLACDFRVASKSSKMGLPETGLAIIPGAGGTQRLPRLIGIPRAKELIFTGAILDSKRALEIGLVQYETEKGEAFDKAIEIAKQIIPKGPIAIRMAKQAIDRGMNVDQASGMIIEQASYAQVIPTKDRIEGLTAFKEKRKPIYKGE", "length": 303 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JLZ3-1", "protein_name": "Methylglutaconyl-CoA hydratase, mitochondrial", "gene_name": "Auh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAPGALGALRTGRVRLVAACCARLGPAAWARGTAPRRGYSSEVKTEDELRVRHLEEENRGIVVLGINRAYGKNALSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRSVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE", "length": 314 }, "evidence": [ { "id": "A0A3Q2U419", "url": "https://omabrowser.org/oma/group/A0A3Q2U419/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" }, { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" }, { "name": "enoyl-CoA hydratase activity", "id": "GO:0004300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004300", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" }, { "name": "methylglutaconyl-CoA hydratase activity", "id": "GO:0004490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004490", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U419", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U419" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U419-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 350, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U419-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U419" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U489-1", "uniprot_ac": "A0A3Q2U489", "uniprot_id": "A0A3Q2U489_CHICK", "mass": { "chemical_mass": 61971.0, "monoisotopic_mass": 61971.0 }, "refseq": { "ac": "XP_015131905", "name": "something about silencing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131905" }, "gene_names": [ { "name": "UTP3", "type": "recommended", "evidence": [ { "id": "A0A3Q2U489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ] }, { "name": "UTP3", "type": "synonym", "evidence": [ { "id": "XP_015131905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131905" } ] } ], "protein_names": [ { "name": "UTP3 small subunit processome component", "type": "synonym", "evidence": [ { "id": "A0A3Q2U489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489/entry#names_and_taxonomy" } ] }, { "name": "something about silencing protein 10", "type": "synonym", "evidence": [ { "id": "XP_015131905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131905" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131905" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UTP3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489", "locus": { "chromosome": "4", "start_pos": 49532893, "end_pos": 49503976, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004086", "url": "https://www.ensembl.org/id/ENSGALG00010004086" } ] } } ], "crossref": [ { "id": "ENSGALG00000047103", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000047103", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422644", "url": "https://www.ncbi.nlm.nih.gov/gene/422644", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422644", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEYIRPQ", "url": "https://omabrowser.org/oma/group/EEYIRPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U489", "url": "https://www.orthodb.org/?gene=A0A3Q2U489", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFX0", "url": "https://www.orthodb.org/?gene=A0A8V0XFX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13237:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13237:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015131905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U489-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTRRGTVLRPPPRPANRHDAEDDDDEEVPGGEVGPEGLGDEVEDFHEAQFREVMAALESGEEAGDSEEEEEEEVLGLQLPEEDEEEEEEEEEEEEEEEGEPGEEVEEARESRFYEDRSAEEDGGDEEEEENEDEDEENEDEDEDLSMESDLEERGKDTDLPHELSWGRRKQLYYDTDYGGDAQAKGKRSQQDVDAEEEEEEQEAKVIQRRLVEDLGEDDYGLDVIQGYLAEQQKTHDSKGQKIAKDLQALSKKEQLKLLKQESPELLQLIEDFEVKLMELKDELHPLLQMVKNGTIPQGKGSRYLQTKYQLYLNYCANISFYLVLKSKRMPVHSHPIIERLVAYRNIINDLAVIDQKLSSQVRLLLKNYYDKKEEKLRERKKFPVLLQPTAKKTKRKREPALANGRLAAEELADESDLDGEAALKYYKMMEEKLKLKRKRTEEQETPEEPVTEEDPNQKRGVTYQMIKNKGLTPRRKKIDRNPRVKHREKFRRAKIRRKGQVREVRREIHRYSGELSGIRAGVKKSRKLQ", "length": 531, "header": "tr|A0A3Q2U489-1|A0A3Q2U489_CHICK Isoform 1 of UTP3 small subunit processome component OS=Gallus gallus OX=9031 GN=UTP3 PE=1 SV=1 CANONICAL=A0A3Q2U489-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U489-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489/entry", "sequence": { "sequence": "MRTRRGTVLRPPPRPANRHDAEDDDDEEVPGGEVGPEGLGDEVEDFHEAQFREVMAALESGEEAGDSEEEEEEEVLGLQLPEEDEEEEEEEEEEEEEEEGEPGEEVEEARESRFYEDRSAEEDGGDEEEEENEDEDEENEDEDEDLSMESDLEERGKDTDLPHELSWGRRKQLYYDTDYGGDAQAKGKRSQQDVDAEEEEEEQEAKVIQRRLVEDLGEDDYGLDVIQGYLAEQQKTHDSKGQKIAKDLQALSKKEQLKLLKQESPELLQLIEDFEVKLMELKDELHPLLQMVKNGTIPQGKGSRYLQTKYQLYLNYCANISFYLVLKSKRMPVHSHPIIERLVAYRNIINDLAVIDQKLSSQVRLLLKNYYDKKEEKLRERKKFPVLLQPTAKKTKRKREPALANGRLAAEELADESDLDGEAALKYYKMMEEKLKLKRKRTEEQETPEEPVTEEDPNQKRGVTYQMIKNKGLTPRRKKIDRNPRVKHREKFRRAKIRRKGQVREVRREIHRYSGELSGIRAGVKKSRKLQ", "length": 531, "header": "tr|A0A3Q2U489-1|A0A3Q2U489_CHICK Isoform 1 of UTP3 small subunit processome component OS=Gallus gallus OX=9031 GN=UTP3 PE=1 SV=1 CANONICAL=A0A3Q2U489-1" }, "locus": { "chromosome": "4", "start_pos": 49532893, "end_pos": 49532727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009499.1", "url": "https://www.ensembl.org/id/ENSGALT00010009499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005602.1", "url": "https://www.ensembl.org/id/ENSGALP00010005602.1" } ] } }, { "isoform_ac": "A0A8V0XFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX0/entry", "sequence": { "sequence": "MRTRRGTVLRPPPRPANRHDAEDDDDEEVPGGEVGPEGLGDEVEDFHEAQFREVMAALESGEEAGDSEEEEEEEVLGLQLPEEDEEEEEEEEEEEEEEEGEPGEEVEEARESRFYEDRSAEEDGGDEEEEENEDEDEENEDEDEDLSMESDLEERGKDTDLPHELSWGRRKQLYYDTDYGGDAQAKGKRSQQDVDAEEEEEEQEAKVIQRRLVEDLGEDDYGLDVIQGYLAEQQKTHDSKGQKIAKDLQALSKKEQLKLLKQESPELLQLIEDFEVKLMELKDELHPLLQMVKNGTIPQGKGSRYLQTKYQLYLNYCANISFYLVLKSKRMPVHSHPIIERLVAYRNIINDLAVIDQKLSSQVRLLLKNYYDKKEEKLRERKKFPVLLQPTAKKTKRKREPALANGRLAALKYYKMMEEKLKLKRKRTEEQETPEEPVTEEDPNQKRGVTYQMIKNKGLTPRRKKIDRNPRVKHREKFRRAKIRRKGQVREVRREIHRYSGELSGIRAGVKKSRKLQ", "length": 517, "header": "tr|A0A8V0XFX0-1|A0A3Q2U489_CHICK Computationally mapped isoform of UTP3 small subunit processome component OS=Gallus gallus OX=9031 GN=UTP3 PE=1 SV=1 CANONICAL=A0A3Q2U489-1" }, "locus": { "chromosome": "4", "start_pos": 49530198, "end_pos": 49528606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009495.1", "url": "https://www.ensembl.org/id/ENSGALT00010009495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005598.1", "url": "https://www.ensembl.org/id/ENSGALP00010005598.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422644", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TAU9-1", "protein_name": "UTP3 small subunit processome component", "gene_name": "UTP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRRSQRRGAAKWAALRSKAGRGPVEENEDDLESPPSPGDSSYYQDKVDDFHEARSRAALAKGWSEVESGDEEEDGDEEEEVLALDVADEDDEDGESAGDEEEEEEDGGSSVESEAEASVDPSLSWGQRKKVYYDTDYGSKSRGRRSQQEVEEEEREEEEEAQLIQRRLAQTLQEDDFGVTWVTAFAKPAPQVNEAETRVVKDLAKISVKEKLKMLRKESPELLELIDDLKVKLTEMKDELEPLLQLVEQRVIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDEKLSSEIRHLLTLKDGAGKKELTLKVKSTKAKPKSVSETSAAAVTDLSDDSDFDEEAALKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRREEQRYSGELSGIRAGVKKSIKLK", "length": 474 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MSF6-1", "protein_name": "UTP3 small subunit processome component", "gene_name": "UTP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGRSGRRARGAAKWAAVRAKASRDPADDDGEDLESPPSPGDSSYYQDKVDDFHEARSRAALAKGWSEIESGDEEDGDEEEEVLALDVADEDDEDGESEEGDDDDGGSSVQSETEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEVEEEEREEEAEAQLIQRRLAQALQEDDFGVTWVEAFAKPVPQVNEAETRVVKDLAKVSVKEKLKMLRKESPELLELIDDLKVKLTEMKDELEPLLQLVEQKIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRYMLTLKDGAGKKELNLKAKSMKAKPKSVSETSAAALAVRDLSDDSDFDEEAALKYYKEMEERQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRKAKIRRRGQVREVRREEQRYTGELSGIRAGVKKSIKLK", "length": 474 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXX4-1", "protein_name": "Something about silencing protein 10", "gene_name": "Utp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKRSRRRGAAQWATVRAKAGRTATDENEDDLGSPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDDDEEEEVLPLNIDDENDEDGESSEEEEDGEDDDGGSSVQSEAEASVDPSLSWGQRKRLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQVIQRRLTQALQEDDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEPLIQLVEKGVIPPGKGSQYLKTKYNLYLNYCANISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTAKEGAGKKDLNPKAKLTKTKPKSAKQTDVNADLTEEPEFDEAALEFYKEMEDRPELKRKKEENSAEEQALEEQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRREEQRYSGELSGIRAGVKKSIKLK", "length": 470 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8L3P4-1", "protein_name": "Protein THALLO", "gene_name": "THAL", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKKGGTLKRSSKSTKTRKDIVEDQYDDEIDAFHKQRDIVPLDVNDDTDESDEDDVQPVFDLQGVDDESEEDEDTEDEEEAENGLTAKMIRQKKYLRAKFGDGDDEMADDDKDKEEDKRSTWGGRSGLYHSGDNVDFDILSSDDEDIKAEEEEVIRLRAEQLGSITAADAGLDDDSEEDSDRELTMEEISDKGKQATKSITDKKEKGDKDTHVEEIKKDINSLSKEEQMDVVYSSAPEIVGLLSELNDAVEELESKINPVMNKLKEGEISLNGLARYLEVKQLLLLTYCQSITFYLLLKSEGQPIRDHPVLARLVEIKSLLDKIKELDEELPPGFEESLARSIANGAVQKVVKEDQLTSPVSDSVDRITQDTAKPMKIDNAREEKKKKGEKRKHQNDLVDVQSEEMLKLRAALEGKLRTNGVLGSTVSKSDKAQKRQKLANRKLETFDDYVDDADNSTHNVTADKLTKLVSTKRKPKTISGDDDLPQRDDIGERRRKFELRVLAGAGVKSSEGDGRNKNGAFASDDEDDNDGDNNDMVDNDGESEDEFYKQVKQKQQAKRAAKAEIYSRKPHLMPSSPEHVDGKRHISNQMVSNRGLTRQRNRDLKNPRKKYRKNYEKKVTRRKGQVRDIRKQTGPYAGEARGINPNTSRSIRM", "length": 654 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9I7W5-1", "protein_name": "Something about silencing protein 10", "gene_name": "Sas10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSDGDDYVMSGSDQEYDDEEREILEDLRKQRKKPHDPVQEVLGFSDDDDDDDDDDEEEQQDVAELMRDSDIEGAEDDDRDLPNTMDWGSKRSTYYNTDFVDQDYSSYNAQEEEQARAEEEEAKKIQLRLAKRMSEADFQLDNVEAAPAGSSDDNELSHITKVTSDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLLKPVLNYVRKHDVPMVPALQYAGLCHTVLTTYCSNVAFYLLLKARRIDVKAHPVIRRLVQLKDLIEELKPRYEEYIRPQLEALLERIEDGDAFTVLDVAQRKAKLQILNKYNDGQQASVSSDDDDNDDDDDAESKEKDLQEEAGEEEEEEDARRGITYQMAKNKGLTPHRKKELRNPRVKHRGKYRKALIRRKGAVRTVRKELQRYGGELSGIKAGVTKSVKFRT", "length": 428 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9JI13-1", "protein_name": "Something about silencing protein 10", "gene_name": "Utp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKKSRRRGAAQWAAVRAQAGLTATDENEDDLGLPPSPGDSSYYQDQVDEFHEARSRAVLAKGWNEVESGEEDGDEEEEVLPLDIDDGDDEDGESSEEEEVGEDDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEVEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLKKESPELLELIEDLQAKLTEVKDELEPLLQLVEKGVIPTGRGSEYLKTKYNLYLNYCANISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTAKDGAVKKEMTPKAKLTKTKPKSVKQAAAVALTDEPDFDGAALKYYKEMEDRQELKRKKEENSAEEQALEEQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRKAKIRRRGQVREVRREEQRYSGELSGIRAGVKKSIKLK", "length": 469 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQZ2-1", "protein_name": "Something about silencing protein 10", "gene_name": "UTP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGVKKSIKLK", "length": 479 }, "evidence": [ { "id": "A0A3Q2U489", "url": "https://omabrowser.org/oma/group/A0A3Q2U489/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U489", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U489" }, { "id": "PF09368", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09368" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sas10 C-terminal", "eco_id": "ECO_0000259", "start_pos": 458, "end_pos": 530, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 319, "end_pos": 321 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U4U2-1", "uniprot_ac": "A0A3Q2U4U2", "uniprot_id": "A0A3Q2U4U2_CHICK", "mass": { "chemical_mass": 42338.0, "monoisotopic_mass": 42338.0 }, "refseq": { "ac": "XP_003642076", "name": "probable G-protein coupled receptor 27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642076" }, "gene_names": [ { "name": "GPR27", "type": "recommended", "evidence": [ { "id": "A0A3Q2U4U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2" } ] }, { "name": "GPR27", "type": "synonym", "evidence": [ { "id": "XP_003642076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642076" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 27", "type": "synonym", "evidence": [ { "id": "A0A3Q2U4U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 27", "type": "synonym", "evidence": [ { "id": "XP_003642076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642076" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642076" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U4U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR27", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2", "locus": { "chromosome": "12", "start_pos": 16482445, "end_pos": 16478954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022232", "url": "https://www.ensembl.org/id/ENSGALG00010022232" } ] } } ], "crossref": [ { "id": "ENSGALG00000054150", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054150", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15005", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15005", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416094", "url": "https://www.ncbi.nlm.nih.gov/gene/416094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416094", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIHSHRK", "url": "https://omabrowser.org/oma/group/FIHSHRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U4U2", "url": "https://www.orthodb.org/?gene=A0A3Q2U4U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19268:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19268:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642076", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U4U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U4U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANSSELGSSSSPHLPSAGGLLSASGLKLATLGLILCVSLAGNVLFAWLILKDRHLHRAPYYLLLDLCLADGLRSLACFPFVMLSVRSGAAWPHGLLSCKVLAFLAVLFCFHAAFLLFCVGVTRYMAIAHHRFYAKRMTGWTCLAVVCMVWTLSMAMAFPPVFDVGTYKFIREEEQCIFEHRYVKANDTLGFMLMLAAVIAATHLVYIKLLFFIHGHRKMKPAQLVPAISQNWTFHGPGATGQAAANWTAGFGRGPTPPTLVGIRQATHSQIKRLLVLEEFKMEKRLCKMFYMITLLFLLLWSPYIVACYLRVFIKASSIPQVYLTTSVWMTFAQAGVNPILCFIFNKELRVCLRAHFPCCQSIQSTQGTILCDLKSFGM", "length": 380, "header": "tr|A0A3Q2U4U2-1|A0A3Q2U4U2_CHICK Isoform 1 of G protein-coupled receptor 27 OS=Gallus gallus OX=9031 GN=GPR27 PE=4 SV=1 CANONICAL=A0A3Q2U4U2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U4U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2/entry", "sequence": { "sequence": "MANSSELGSSSSPHLPSAGGLLSASGLKLATLGLILCVSLAGNVLFAWLILKDRHLHRAPYYLLLDLCLADGLRSLACFPFVMLSVRSGAAWPHGLLSCKVLAFLAVLFCFHAAFLLFCVGVTRYMAIAHHRFYAKRMTGWTCLAVVCMVWTLSMAMAFPPVFDVGTYKFIREEEQCIFEHRYVKANDTLGFMLMLAAVIAATHLVYIKLLFFIHGHRKMKPAQLVPAISQNWTFHGPGATGQAAANWTAGFGRGPTPPTLVGIRQATHSQIKRLLVLEEFKMEKRLCKMFYMITLLFLLLWSPYIVACYLRVFIKASSIPQVYLTTSVWMTFAQAGVNPILCFIFNKELRVCLRAHFPCCQSIQSTQGTILCDLKSFGM", "length": 380, "header": "tr|A0A3Q2U4U2-1|A0A3Q2U4U2_CHICK Isoform 1 of G protein-coupled receptor 27 OS=Gallus gallus OX=9031 GN=GPR27 PE=4 SV=1 CANONICAL=A0A3Q2U4U2-1" }, "locus": { "chromosome": "12", "start_pos": 16481821, "end_pos": 16480682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054096.1", "url": "https://www.ensembl.org/id/ENSGALT00010054096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032627.1", "url": "https://www.ensembl.org/id/ENSGALP00010032627.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 257, "start_aa": "Thr", "end_pos": 257, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr257", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416094", "resource": "KEGG Pathway" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U4U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U4U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U4U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4U2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 343, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 257 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U665-1", "uniprot_ac": "A0A3Q2U665", "uniprot_id": "A0A3Q2U665_CHICK", "mass": { "chemical_mass": 68250.0, "monoisotopic_mass": 68250.0 }, "refseq": { "ac": "NP_001376253", "name": "kelch-like protein 24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" }, "gene_names": [ { "name": "KLHL24", "type": "recommended", "evidence": [ { "id": "A0A3Q2U665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ] }, { "name": "KLHL24", "type": "synonym", "evidence": [ { "id": "NP_001376253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" } ] } ], "protein_names": [ { "name": "Kelch-like protein 24", "type": "recommended", "evidence": [ { "id": "A0A3Q2U665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665/entry#names_and_taxonomy" } ] }, { "name": "DRE1 protein", "type": "synonym", "evidence": [ { "id": "NP_001376253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" } ] }, { "name": "Kainate receptor-interacting protein for GluR6", "type": "synonym", "evidence": [ { "id": "A0A3Q2U665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 24", "type": "synonym", "evidence": [ { "id": "NP_001376253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" } ] }, { "name": "kelch-like protein 24", "type": "synonym", "evidence": [ { "id": "NP_001376253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.18593.1, SRR13267647.15533.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665", "locus": { "chromosome": "9", "start_pos": 2223049, "end_pos": 2209255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024326", "url": "https://www.ensembl.org/id/ENSGALG00010024326" } ] } } ], "crossref": [ { "id": "A0A3Q2U665", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U665", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002277", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002277", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424763", "url": "https://www.ncbi.nlm.nih.gov/gene/424763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030596", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030596", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NDCYDPV", "url": "https://omabrowser.org/oma/group/NDCYDPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U665", "url": "https://www.orthodb.org/?gene=A0A3Q2U665", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U665-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLILGRRLNREDSGIRDSPATKRKVFEMDPKSLSGPEFFDFSSGSSHAESILQIFNEFRDSRLFTDVIICVEGREFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMDCFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCRNFALQTFEDVSQHEEFLELGKDELIDYICSDELVITKEEMVFEAVMRWVYRAVELRRPVLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPDTNSWLLRATIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPIEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATGIITGVAAMPRPVSYHGCVTIHRYNEKGFKL", "length": 600, "header": "tr|A0A3Q2U665-1|A0A3Q2U665_CHICK Isoform 1 of Kelch-like protein 24 OS=Gallus gallus OX=9031 GN=KLHL24 PE=4 SV=1 CANONICAL=A0A3Q2U665-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U665-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665/entry", "sequence": { "sequence": "MVLILGRRLNREDSGIRDSPATKRKVFEMDPKSLSGPEFFDFSSGSSHAESILQIFNEFRDSRLFTDVIICVEGREFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMDCFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCRNFALQTFEDVSQHEEFLELGKDELIDYICSDELVITKEEMVFEAVMRWVYRAVELRRPVLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPDTNSWLLRATIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPIEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATGIITGVAAMPRPVSYHGCVTIHRYNEKGFKL", "length": 600, "header": "tr|A0A3Q2U665-1|A0A3Q2U665_CHICK Isoform 1 of Kelch-like protein 24 OS=Gallus gallus OX=9031 GN=KLHL24 PE=4 SV=1 CANONICAL=A0A3Q2U665-1" }, "locus": { "chromosome": "9", "start_pos": 2222606, "end_pos": 2213505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059320.1", "url": "https://www.ensembl.org/id/ENSGALT00010059320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036207.1", "url": "https://www.ensembl.org/id/ENSGALP00010036207.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BKJ8-1", "protein_name": "Kelch-like protein 24", "gene_name": "KLHL24", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGREFFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKNFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINGRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SGA5-1", "protein_name": "Kelch-like protein 24", "gene_name": "KLHL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGREFFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKNFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINGRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I3I7-1", "protein_name": "Kelch-like protein 24", "gene_name": "Klhl24", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGHEYFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKTFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCIGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAVYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q56A24-1", "protein_name": "Kelch-like protein 24", "gene_name": "Klhl24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGHEYFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKTFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCIGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAVYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TFL4-1", "protein_name": "Kelch-like protein 24", "gene_name": "KLHL24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGHEFFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKNFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BRG6-1", "protein_name": "Kelch-like protein 24", "gene_name": "Klhl24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGHEYFDFSSGSSHAENILQIFNEFRDSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSLKTLFTKCKTFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRAVDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMSPRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCALRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNRLSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCIGKLFVIGGGPDDNTCSDKVQSYDPETNSWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAVYCYDPVEDYWMHVQNTFSRQENCGMSVCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL", "length": 600 }, "evidence": [ { "id": "A0A3Q2U665", "url": "https://omabrowser.org/oma/group/A0A3Q2U665/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U665", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U665-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 600, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U665-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U665" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U665" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 133, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U6A4-1", "uniprot_ac": "A0A3Q2U6A4", "uniprot_id": "A0A3Q2U6A4_CHICK", "mass": { "chemical_mass": 6967.0, "monoisotopic_mass": 6967.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A3Q2U6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6A4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4", "locus": {} } ], "crossref": [ { "id": "A0A3Q2U6A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U6A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000051178", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000051178", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U6A4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLGTDGNTLIRVVVFRFKIDMLDIGRELLTMYGKSLYSFIKGDCSGDYRNVLLKLCGSED", "length": 62, "header": "tr|A0A3Q2U6A4-1|A0A3Q2U6A4_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A3Q2U6A4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4/entry", "sequence": { "sequence": "MKGLGTDGNTLIRVVVFRFKIDMLDIGRELLTMYGKSLYSFIKGDCSGDYRNVLLKLCGSED", "length": 62, "header": "tr|A0A3Q2U6A4-1|A0A3Q2U6A4_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A3Q2U6A4-1" }, "locus": { "chromosome": "12", "start_pos": 48582, "end_pos": 47417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067846.1", "url": "https://www.ensembl.org/id/ENSGALT00010067846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041589.1", "url": "https://www.ensembl.org/id/ENSGALP00010041589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6A4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U6A4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U6A4" } ], "pmid": "" } ] } 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"ENSGALG00000047167", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000047167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44873", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44873", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44873:SF1", "url": 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"A0A3Q2U7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7S5/entry", "sequence": { "sequence": "ISGEAPRRTLYEVLGVPPTATPAQIKAAYYQQSFRFHPDRNAGSAAAAERFATVSEAYRVLGSAALRRKYDLGALSREDLRDAPRPSGRAPAAPPPTRAAAARRGPAPPPFDFDAFYRAHYGEQLERERVLRARRERLRLYREEAAAQGRLRFLTDLTVGLVFVLGFAMLYGLK", "length": 174, "header": "tr|A0A3Q2U7S5-1|A0A3Q2U7S5_CHICK Isoform 1 of DnaJ homolog subfamily C member 30, mitochondrial OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A3Q2U7S5-1" }, "locus": { "chromosome": "19", "start_pos": 619285, "end_pos": 618011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071332.1", "url": "https://www.ensembl.org/id/ENSGALT00010071332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044023.1", "url": "https://www.ensembl.org/id/ENSGALP00010044023.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": 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"categories": [ "Protein Classification" ] }, { "id": "PF15248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U7W2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDPSMVDHVAQLKFKLLEKRLENEQKNIEKIESPLPTASNRHEDMLQSALKRRKNLLQELREQHLLEELSQPSVPARRHYTNYSAGCPHICQIPFPAPQAETPRIIQQAVRIVTLRKQWLKPALTSPFSFLIQMPPQPATIIQQLPQPPPLIAQIPPAQPFAHPRSGSIKEDMVEMMLMQNAQMHQIIMQNMMLKSLPPTAFAQPARPSYPLLQHTQQDLQISAPVAVKADRPWLSTVHHHHHYSPPRLPLHAMPAGFLMPGEGPPPASSAQGWTSSMPPAMQMWPMY", "length": 289, "header": "tr|A0A3Q2U7W2-1|A0A3Q2U7W2_CHICK Isoform 1 of Chromosome 21 open reading frame 58 OS=Gallus gallus OX=9031 GN=C21orf58 PE=4 SV=1 CANONICAL=A0A3Q2U7W2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U7W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7W2/entry", "sequence": { "sequence": "MTDPSMVDHVAQLKFKLLEKRLENEQKNIEKIESPLPTASNRHEDMLQSALKRRKNLLQELREQHLLEELSQPSVPARRHYTNYSAGCPHICQIPFPAPQAETPRIIQQAVRIVTLRKQWLKPALTSPFSFLIQMPPQPATIIQQLPQPPPLIAQIPPAQPFAHPRSGSIKEDMVEMMLMQNAQMHQIIMQNMMLKSLPPTAFAQPARPSYPLLQHTQQDLQISAPVAVKADRPWLSTVHHHHHYSPPRLPLHAMPAGFLMPGEGPPPASSAQGWTSSMPPAMQMWPMY", "length": 289, "header": "tr|A0A3Q2U7W2-1|A0A3Q2U7W2_CHICK Isoform 1 of Chromosome 21 open reading frame 58 OS=Gallus gallus OX=9031 GN=C21orf58 PE=4 SV=1 CANONICAL=A0A3Q2U7W2-1" }, "locus": { "chromosome": "7", "start_pos": 7194315, "end_pos": 7186164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035968.1", "url": "https://www.ensembl.org/id/ENSGALT00010035968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020875.1", "url": "https://www.ensembl.org/id/ENSGALP00010020875.1" } ] } }, { "isoform_ac": "A0A8V0YS39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS39/entry", "sequence": { "sequence": "MTDPSMVDHVAQLKFKLLEKRLENEQKNIEKIESPLPTASNRHEDMLQSALKRRKNLLQELREQHLLEELSQPSVPARRHYTNYSAGCPHICQIPFPAPQAETPRIIQQAMPPQPATIIQQLPQPPPLIAQIPPAQPFAHPRSGSIKEDMVEMMLMQNAQMHQIIMQNMMLKSLPPTAFAQPARPSYPLLQHTQQDLQISAPVAVKADRPWLSTVHHHHHYSPPRLPLHAMPAGFLMPGEGPPPASSAQGWTSSMPPAMQMWPMY", "length": 265, "header": "tr|A0A8V0YS39-1|A0A3Q2U7W2_CHICK Computationally mapped isoform of Chromosome 21 open reading frame 58 OS=Gallus gallus OX=9031 GN=C21orf58 PE=4 SV=1 CANONICAL=A0A3Q2U7W2-1" }, "locus": { "chromosome": "7", "start_pos": 7194315, "end_pos": 7186164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035973.1", "url": "https://www.ensembl.org/id/ENSGALT00010035973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020879.1", "url": "https://www.ensembl.org/id/ENSGALP00010020879.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424040", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424040", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G5E8K1-1", "protein_name": "RIKEN cDNA 2610028H24 gene", "gene_name": "2610028H24Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLDSSMADQMTRLRLQLLEQMLEQERDSMDRAGQQEKSDTALQSALRRRKDLLQRLWEQQLMDEHSPAHAWRMHGRAAVPTLNPEVPPTDVFPAASPPLPRPPEPPRIIQHPVPQAPATIIQQLPQQQPLIAQISPPQAFPTPRSGSIKEDMVEMMLMQNAQMHQILMQNMMLKALPPGSSGPRAATLQDQRWMHHGVPRAEKQKPPPVHHHHHYAPTTQLPAASTAGAPAGYAMWPPVVAATAFPHAASFLPTVSHLTEASTSHPSYP", "length": 270 }, "evidence": [ { "id": "A0A3Q2U7W2", "url": "https://omabrowser.org/oma/group/A0A3Q2U7W2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P58505-1", "protein_name": "Uncharacterized protein C21orf58", "gene_name": "C21orf58", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPASNRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP", "length": 322 }, "evidence": [ { "id": "A0A3Q2U7W2", "url": "https://omabrowser.org/oma/group/A0A3Q2U7W2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U7W2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U7W2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U7W2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U7Z3-1", "uniprot_ac": "A0A3Q2U7Z3", "uniprot_id": "A0A3Q2U7Z3_CHICK", "mass": { "chemical_mass": 150883.0, "monoisotopic_mass": 150883.0 }, "refseq": { "ac": "XP_004940474", "name": "inhibitor of Bruton tyrosine kinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940474" }, "gene_names": [ { "name": "IBTK", "type": "recommended", "evidence": [ { "id": "A0A3Q2U7Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ] }, { "name": "IBTK", "type": "synonym", "evidence": [ { "id": "XP_004940474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940474" } ] } ], "protein_names": [ { "name": "Inhibitor of Bruton tyrosine kinase", "type": "recommended", "evidence": [ { "id": "A0A3Q2U7Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3/entry#names_and_taxonomy" } ] }, { "name": "inhibitor of Bruton tyrosine kinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940474" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940474" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IBTK", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3", "locus": { "chromosome": "3", "start_pos": 78016109, "end_pos": 77948392, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003180", "url": "https://www.ensembl.org/id/ENSGALG00010003180" } ] } } ], "crossref": [ { "id": "ENSGALG00000015864", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015864", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18500", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18500", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421844", "url": "https://www.ncbi.nlm.nih.gov/gene/421844", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421844", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421844", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGINTDH", "url": "https://omabrowser.org/oma/group/CGINTDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U7Z3", "url": "https://www.orthodb.org/?gene=A0A3Q2U7Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AWN9", "url": "https://www.orthodb.org/?gene=A0A3Q3AWN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFJ0", "url": "https://www.orthodb.org/?gene=A0A8V0XFJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XIB5", "url": "https://www.orthodb.org/?gene=A0A8V0XIB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AWN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AWN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AWN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AWN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSLMPDCTSKCRSLQHALDVISVVTRGSEGQIKAFLSSYCYNAATIKDAFGRNVLHLASSCGKKGVLDWLAETKGVDLLAKDKESGWTALHRSIFYGYIDCVLSLLKHGVSLYIQDKEGLSALDLVMKDRPIHVVFKKTDLTEVYTWGNNINFTLGHGGQQSKHHPELVDLFPRNSVYIKQVVLCKFHSVFLSHKGQIYTCGHGQGGRLGHGDEQTCLVPRLVEGLSSHQCSQIAAAKDHTVVLTEDGCVYTFGLNTFHQLGILPPPANCSVPRQVQAKNLKGRMVIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDVSVSLVSASDGATVCVTERGDIYLLADYQCKKIASKQLNLKKVLVNGGYLEYKVDTQHLKENGGQKICILALDEAGRIFCWKSSNNSMKQCRWVYGRQVFMSDVALNRNEMMFVTQDGEAFTGKWLEEGRKVLEKKELVSSLPNASTEMSCSYDTNNAYERIRLQKLAFVHRAVSVATDPNGCNFAVLQSDPKTSLYEIPSVSLSSFGEDFGKLLDETDEMDSIHDVTLQIGTRTYAVHKYILAVRSDFFKKLFVSSDSQLETPDVYRKDEDAVGCDLYVIEKVHPDLFAYLLQFIYTDTCDLLTHGYKPKILHKEKSEEYQDTLISNLNKMSFDEDVNRKSAFEIYRNNQVQVLNEKQKNKSKKGKIVGGEANLIKMLQSAAKKFGLSNLSGRLDGVRLENGKINVVNRKNGNKLKFNQKKCSYLCDVTLKSSDGKEFPCHKCVLCARLDYFHSMLSSSWIEASSCSALEMPIHSDILQIIIDYLYTDEALAIKDSQNVEFICNVLVVADQLLISRLKEICEVAIAEKLTLKNAAELLEFSAMYNAEQLKLSCLQFIGLNMAALLETRTLDVLSDDVVKDLSVYYRKMIPAMVRRVITPYPDGPDLSCFEPEEGENFVFIREEMNTEQNSQEALFKRAKTKAKKKPRKRSDSSGGYNLSDIIQSPASTGSIKLDKTNSVESLPELLTSDSEGSYAGVSSPRDLQSPDFTKVFHPERTEMKDKACSLVMKASQQNKEMKSCKGSSALTQSVPQSIPRTKNSSATSPNWVASSFSPASPPAMDLRTIMEIEENMQKCGTMPKTNSSRMTSHGIKLSQKQRKMIALAAKDNVSVTTTAEPTPLVTIPPTPTKVAKLGNAWSSSLHSPLPKSFRDLVMEEEKYMSANNLPGTTIKRAGYKGAEDSPVQSTARCMARSSPGLEGHVLDSPQLESHNPWLATSPTNSPVMAPVMFASIVEEERQQEAALIRSREKPLALIQIEECAIQDLLIHYEAFDNPDEFVTVERAPQGPMATPMWNKH", "length": 1357, "header": "tr|A0A3Q2U7Z3-1|A0A3Q2U7Z3_CHICK Isoform 1 of Inhibitor of Bruton tyrosine kinase OS=Gallus gallus OX=9031 GN=IBTK PE=4 SV=1 CANONICAL=A0A3Q2U7Z3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3/entry", "sequence": { "sequence": "MNSLMPDCTSKCRSLQHALDVISVVTRGSEGQIKAFLSSYCYNAATIKDAFGRNVLHLASSCGKKGVLDWLAETKGVDLLAKDKESGWTALHRSIFYGYIDCVLSLLKHGVSLYIQDKEGLSALDLVMKDRPIHVVFKKTDLTEVYTWGNNINFTLGHGGQQSKHHPELVDLFPRNSVYIKQVVLCKFHSVFLSHKGQIYTCGHGQGGRLGHGDEQTCLVPRLVEGLSSHQCSQIAAAKDHTVVLTEDGCVYTFGLNTFHQLGILPPPANCSVPRQVQAKNLKGRMVIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDVSVSLVSASDGATVCVTERGDIYLLADYQCKKIASKQLNLKKVLVNGGYLEYKVDTQHLKENGGQKICILALDEAGRIFCWKSSNNSMKQCRWVYGRQVFMSDVALNRNEMMFVTQDGEAFTGKWLEEGRKVLEKKELVSSLPNASTEMSCSYDTNNAYERIRLQKLAFVHRAVSVATDPNGCNFAVLQSDPKTSLYEIPSVSLSSFGEDFGKLLDETDEMDSIHDVTLQIGTRTYAVHKYILAVRSDFFKKLFVSSDSQLETPDVYRKDEDAVGCDLYVIEKVHPDLFAYLLQFIYTDTCDLLTHGYKPKILHKEKSEEYQDTLISNLNKMSFDEDVNRKSAFEIYRNNQVQVLNEKQKNKSKKGKIVGGEANLIKMLQSAAKKFGLSNLSGRLDGVRLENGKINVVNRKNGNKLKFNQKKCSYLCDVTLKSSDGKEFPCHKCVLCARLDYFHSMLSSSWIEASSCSALEMPIHSDILQIIIDYLYTDEALAIKDSQNVEFICNVLVVADQLLISRLKEICEVAIAEKLTLKNAAELLEFSAMYNAEQLKLSCLQFIGLNMAALLETRTLDVLSDDVVKDLSVYYRKMIPAMVRRVITPYPDGPDLSCFEPEEGENFVFIREEMNTEQNSQEALFKRAKTKAKKKPRKRSDSSGGYNLSDIIQSPASTGSIKLDKTNSVESLPELLTSDSEGSYAGVSSPRDLQSPDFTKVFHPERTEMKDKACSLVMKASQQNKEMKSCKGSSALTQSVPQSIPRTKNSSATSPNWVASSFSPASPPAMDLRTIMEIEENMQKCGTMPKTNSSRMTSHGIKLSQKQRKMIALAAKDNVSVTTTAEPTPLVTIPPTPTKVAKLGNAWSSSLHSPLPKSFRDLVMEEEKYMSANNLPGTTIKRAGYKGAEDSPVQSTARCMARSSPGLEGHVLDSPQLESHNPWLATSPTNSPVMAPVMFASIVEEERQQEAALIRSREKPLALIQIEECAIQDLLIHYEAFDNPDEFVTVERAPQGPMATPMWNKH", "length": 1357, "header": "tr|A0A3Q2U7Z3-1|A0A3Q2U7Z3_CHICK Isoform 1 of Inhibitor of Bruton tyrosine kinase OS=Gallus gallus OX=9031 GN=IBTK PE=4 SV=1 CANONICAL=A0A3Q2U7Z3-1" }, "locus": { "chromosome": "3", "start_pos": 78001662, "end_pos": 77956429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007419.1", "url": "https://www.ensembl.org/id/ENSGALT00010007419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004436.1", "url": "https://www.ensembl.org/id/ENSGALP00010004436.1" } ] } }, { "isoform_ac": "A0A3Q3AWN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AWN9/entry", "sequence": { "sequence": "MNSLMPDCTSKCRSLQHALDVISVVTRGSEGQIKAFLSSYCYNAATIKDAFGRNVLHLASSCGKKGVLDWLAETKGVDLLAKDKESGWTALHRSIFYGYIDCVLSLLKHGVSLYIQDKEGLSALDLVMKDRPIHVVFKKTDLTEVYTWGNNINFTLGHGGQQSKHHPELVDLFPRNSVYIKQVVLCKFHSVFLSHKGQIYTCGHGQGGRLGHGDEQTCLVPRLVEGLSSHQCSQIAAAKDHTVVLTEDGCVYTFGLNTFHQLGILPPPANCSVPRQVQAKNLKGRMVIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDVSVSLVSASDGATVCVTERGDIYLLADYQCKKIASKQLNLKKVLVNGGYLEYKVDTQHLKENGGQKICILALDEAGRIFCWKSSNNSMKQCRWVYGRQVFMSDVALNRNEMMFVTQDGEAFTGKWLEEGRKVLEKKELVSSLPNASTEMSCSYDTNNAYERIRLQKLAFVHRAVSVATDPNGCNFAVLQSDPKTSLYEIPSVSLSSFGEDFGKLLDETDEMDSIHDVTLQIGTRTYAVHKYILAVRSDFFKKLFVSSDSQLETPDVYRKDEDAVGCDLYVIEKVHPDLFAYLLQFIYTDTCDLLTHGYKPKILHKEKSEEYQDTLISNLNKMSFDEDVNRKSAFEIYRNNQVQVLNEKQKNKSKKGKIVGGEANLIKMLQSAAKKFGLSNLSGRLDGVRLENGKINVVNRKNGNKLKFNQKKCSYLCDVTLKSSDGKEFPCHKCVLCARLDYFHSMLSSSWIEASSCSALEMPIHSDILQIIIDYLYTDEALAIKDSQNVEFICNVLVVADQLLISRLKEICEVAIAEKLTLKNAAELLEFSAMYNAEQLKLSCLQFIGLNMAALLETRTLDVLSDDVVKDLSVYYRKMIPAMVRRVITPYPDGPDLSCFEPEEGENFVFIREEMNTEQNSQEALFKRAKTKAKKKPRKRSDSSGGYNLSDIIQSPASTGSIKLDKTNSVESLPELLTSDSEGSYAGVSSPRDLQSPDFTKVFHPERTEMKDKACSLVMKASQQNKEMKSCKGSSALTQSVPQSIPRTKNSSATSPNWVASSFSPASPPAMDLRTIMEIEENMQKCGTMPKTNSRSSSLHSPLPKSFRDLVMEEEKYMSANNLPGTTIKRAGYKGAEDSPVQSTARCMARSSPGLEGHVLDSPQLESHNPWLATSPTNSPVMAPVMFASIVEEERQQEAALIRSREKPLALIQIEECAIQDLLIHYEAFDNPDEFVTVERAPQGPMATPMWNKH", "length": 1304, "header": "tr|A0A3Q3AWN9-1|A0A3Q2U7Z3_CHICK Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Gallus gallus OX=9031 GN=IBTK PE=4 SV=1 CANONICAL=A0A3Q2U7Z3-1" }, "locus": { "chromosome": "3", "start_pos": 78001662, "end_pos": 77956429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007426.1", "url": "https://www.ensembl.org/id/ENSGALT00010007426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004443.1", "url": "https://www.ensembl.org/id/ENSGALP00010004443.1" } ] } }, { "isoform_ac": "A0A8V0XFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFJ0/entry", "sequence": { "sequence": "MNSLMPDCTSKCRSLQHALDVISVVTRGSEGQIKAFLSSYCYNAATIKDAFGRNVLHLASSCGKKGVLDWLAETKGVDLLAKDKESGWTALHRSIFYGYIDCVLSLLKHGVSLYIQDKEGLSALDLVMKDRPIHVVFKKTDLTEVYTWGNNINFTLGHGGQQSKHHPELVDLFPRNSVYIKQVVLCKFHSVFLSHKGQIYTCGHGQGGRLGHGDEQTCLVPRLVEGLSSHQCSQIAAAKDHTVVLTEDGCVYTFGLNTFHQLGILPPPANCSVPRQVQAKNLKGRMVIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDVSVSLVSASDGATVCVTERGDIYLLADYQCKKIASKQLNLKKVLVNGGYLEYKVDTQHLKENGGQKICILALDEAGRIFCWKSSNNSMKQCRWVYGRQVFMSDVALNRNEMMFVTQDGEAFTGKWLEEGRKVLEKKELVSSLPNASTEMSCSYDTNNAYERIRLQKLAFVHRAVSVATDPNGCNFAVLQSDPKTSLYEIPSVSLSSFGEDFGKLLDETDEMDSIHDVTLQIGTRTYAVHKYILAVRSDFFKKLFVSSDSQLETPDVYRKDEDAVGCDLYVIEKVHPDLFAYLLQFIYTDTCDLLTHGYKPKILHKEKSEEYQDTLISNLNKMSFDEDVNRKSAFEIYRNNQVQVLNEKQKNKSKKGKIVGGEANLIKMLQSAAKKFGLSNLSGRLDGVRLENGKINVVNRKNGNKLKFNQKKCSYLCDVTLKSSDGKEFPCHKCVLCARLDYFHSMLSSSWIEASSCSALEMPIHSDILQIIIDYLYTDEALAIKDSQNVEFICNVLVVADQLLISRLKEICEVAIAEKLTLKNAAELLEFSAMYNAEQLKLSCLQFIGLNMAALLETRTLDVLSDDVVKDLSVYYRKMIPAMVRRVITPYPDGPDLSCFEPEEGENFVFIREEMNTEQNSQEALFKRAKTKAKKKPRKRSDSSGGYNLSDIIQSPASTGSIKLDKTNSVESLPELLTSDSEGSYAGVSSPRDLQSPDFTKVFHPERTEMKDKACSLVMKASQQNKEMKSCKGSSALTQSVPQSIPRTKNSSATSPNWVASSFSPASPPAMDLRTIMEIEENMQKCGTMPKTNSSRMTSHGIKLSQKQRKMIALAAKDNVSVTTTAEPTPLVTIPPTPTKVAKLGNAWSSSLHSPLPKSFRDLVMEEEKYMSANNLPGTTIKRAGYKGAEDSPVQSTARCMARSSPGLEGHVLDSPQLESHK", "length": 1272, "header": "tr|A0A8V0XFJ0-1|A0A3Q2U7Z3_CHICK Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Gallus gallus OX=9031 GN=IBTK PE=4 SV=1 CANONICAL=A0A3Q2U7Z3-1" }, "locus": { "chromosome": "3", "start_pos": 78000525, "end_pos": 77956429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007413.1", "url": "https://www.ensembl.org/id/ENSGALT00010007413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004433.1", "url": "https://www.ensembl.org/id/ENSGALP00010004433.1" } ] } }, { "isoform_ac": "A0A8V0XIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIB5/entry", "sequence": { "sequence": "MNSLMPDCTSKCRSLQHALDVISVVTRGSEGQIKAFLSSYCYNAATIKDAFGRNVLHLASSCGKKGVLDWLAETKGVDLLAKDKESGWTALHRSIFYGYIDCVLSLLKHGVSLYIQDKEGLSALDLVMKDRPIHVVFKKTDLTEVYTWGNNINFTLGHGGQQSKHHPELVDLFPRNSVYIKQVVLCKFHSVFLSHKGQIYTCGHGQGGRLGHGDEQTCLVPRLVEGLSSHQCSQIAAAKDHTVVLTEDGCVYTFGLNTFHQLGILPPPANCSVPRQVQAKNLKGRMVIGVAAGRFHTVLWTKEAVYTMGLNGGQLGYLLDPNGEKCVTAPRQVSALHHKDVSVSLVSASDGATVCVTERGDIYLLADYQCKKIASKQLNLKKVLVNGGYLEYKVDTQHLKENGGQKICILALDEAGRIFCWKSSNNSMKQCRWVYGRQVFMSDVALNRNEMMFVTQDGEAFTGKWLEEGRKVLEKKELVSSLPNASTEMSCSYDTNNAYERIRLQKLAFVHRAVSVATDPNGCNFAVLQSDPKTSLYEIPSVSLSSFGEDFGKLLDETDEMDSIHDVTLQIGTRTYAVHKYILAVRSDFFKKLFVSSDSQLETPDVYRKDEDAVGCDLYVIEKVHPDLFAYLLQFIYTDTCDLLTHGYKPKILHKEKSEEYQDTLISNLNKMSFDEDVNRKSAFEIYRNNQVQVLNEKQKNKSKKGKIVGGEANLIKMLQSAAKKFGLSNLSGRLDGVRLENGKINVVNRKNGNKLKFNQKKCSYLCDVTLKSSDGKEFPCHKCVLCARLDYFHSMLSSSWIEASSCSALEMPIHSDILQIIIDYLYTDEALAIKDSQNVEFICNVLVVADQLLISRLKEICEVAIAEKLTLKNAAELLEFSAMYNAEQLKLSCLQFIGLNMAALLETRTLDVLSDDVVKDLSVYYRKMIPAMVRRVITPYPDGPDLSCFEPEEGENFVFIREEMNTEQNSQEALFKRAKTKAKKKPRKRSDSSGGYNLSDIIQSPASTGSIKLDKTNSVESLPELLTSDSEGSYAGVSSPRDLQSPDFTKVFHPERTEMKDKACSLVMKASQQNKEMKSCKGSSALTQSVPQSIPRTKNSSATSPNWVASSFSPASPPAMDLRTIMEIEENMQKCGTMPKTNSSRMTSHGIKLSQKQRKMIALAAKDNVSVTTTAEPTPLVTIPPTPTKVAKLGNAWSSSLHSPLPKSFRDLVMEEEKYMSANNLPGTTIKRAGYKGAEDSPVQSTARCMARSSPGLEGHVLDSPQLESHNPWLATSPTNSPVMAPVMFASIVEEERQQEAALIRSREKPLALIQFLWLRWTNLLSRIILSVE", "length": 1334, "header": "tr|A0A8V0XIB5-1|A0A3Q2U7Z3_CHICK Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Gallus gallus OX=9031 GN=IBTK PE=4 SV=1 CANONICAL=A0A3Q2U7Z3-1" }, "locus": { "chromosome": "3", "start_pos": 78016107, "end_pos": 77956429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007427.1", "url": "https://www.ensembl.org/id/ENSGALT00010007427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004444.1", "url": "https://www.ensembl.org/id/ENSGALP00010004444.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1187, "start_aa": "Thr", "end_pos": 1187, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1187", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421844", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421844", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUJ7-1", "protein_name": "Inhibitor of Bruton tyrosine kinase", "gene_name": "Ibtk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSAAPDCTAKCRSLKHALDVLSVITKGSERQIKIFLSSYCYNAATVKDAFGRNALHLVSSCGKKAVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHINCVWSLLKHGVSLYMQDKEGLSPLDLLMKDRPAHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSRVYVKQVVLCKFHSVFLSQQGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHSCSQVAAAKDHTVVLTEDGCVYTFGLNTFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKNSEKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTLLELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRMIMNKKSEDSKGSPESRLHAVNCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGEDDPVKMLQNVAKKFGLSNLSSRLDGVRYENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQAEILKVILDYLYTDEAVVIKESQNVDFVCSVLVVADQLLITRLKEMCEVALAENLTLKNAAMLLEFASMYNAEQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMVPAMERRVITPYQDGPDISCVQAEDGEVFLKEEISLEPNHSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSAKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHSDKVEGKAKPYVNGTPLPWTREDLKPWEKSPTTKSAPQFIPSSRVDTSGSSSWVAGSCSPVSPPVVDLRTIMETEANRQKYGAAPKSNLGKIISHGIKLSQKQRKMMALTTKENNSGTNSMEPILTAPSKSPKPVNAWAPLHSPSSSSFRNFLLEEKKPVPGRGSGDHVKKVCFKGTENSPALNVARCSPHGTPGLESNHVSDFPLVDSPNPWLSSSLAASPAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVIVERTPQGPVAVPMWNKHGC", "length": 1352 }, "evidence": [ { "id": "A0A3Q2U7Z3", "url": "https://omabrowser.org/oma/group/A0A3Q2U7Z3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1ZAE2-1", "protein_name": "BTB domain-containing protein", "gene_name": "Dmel\\CG8060", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAARTQEYDCTAKCRLRQHGNAITAALTKRSIDNQKLASFIFKTCGNFANILDDLGRSAVHMSASTARYEILEWLLNHGAYINGQDYESGSSPLHRALYYGSIDCAVLLLRYGASLELLDEDTRCPLQAICRKCDDDDLATDSQNDVLVWGSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLEQVALGAYHSLFCDKKGHLYAVGHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLVFACGLNTDHQLGVRDAAEQLTQFKEVVALRDKGASDLVRVIACDQHSIAYGSRCVYVWGANQGQFGINSNTPSITVPTLIKLPAKTTIRFVEANNAATVIYNEEKIITLCYADKTRYIKTPNYEDLKSISVMGGNLKNSTKGSAAALKLLMLTETNVVYLWYENTQQFYRCNFSPIRLHQIKKILYKCNQVMVLSEDGCVYRGKCNQIALPSSALQEKSRGSLDNWQDNDQNKTEISREHVIRIELQRVPNIDRATYIFCDEGFSSFAVLQESHTKYFRKPSLPRREHSFKKLLHETSDCDAVHDVVFHVDGEKFAAHKFIIYSRAPGLRDLIRCYLDKDIYLNFDHLTGKMFELILNHIYSSYWPTEDDIDCIQQSLGPANPQQRTRTCEMFLPHLEKFQLVELTKYVQSYVRDHQFPLPNARKLFNRLYRSDHPELYDVRIVCKDGKVLGAHKCMLVARLEYFEMMFMHLWAERSSVTMEGVPAEYMEPVLDYLYSLDNEAFCKQGYLETFLYNMITICDQYFIESLQNVCESLILDKISIRKCGEMLEFAAMYNCKILQKGCMDFICQNLSRVLCYRSIEQCDGETLKCLNDHYRKMFKRVFDYRQITPFSEAIEDELLLSFVDGCDVDLNYRMDAESKLKQAAKHKQKDLRKQDARHQYEQQAISSMMRSLSISESTQGTEVPSSPQDSARSEDKNWSRVVDKKDQKRKLAETALKVNNTLKHEDPPTQELVPIERKPLKEQTPPPPSHETEPTTPLSKSYNLDFSSLTPQSQKLSQKQRKRLSSESKSWRTNNPPLVEQSSTPVAVPNAWGVTTTPSGSFNDSFTSPTTGSSTDPTSFANMMRGHATSSTTPTDQSQSFSRILADEKRQRESYERMRNKSLVHTQIEERAIAELREFYNVDNIDDETITIARVSRPSDINFSIWLRQ", "length": 1189 }, "evidence": [ { "id": "A0A3Q2U7Z3", "url": "https://omabrowser.org/oma/group/A0A3Q2U7Z3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6ZPR6-1", "protein_name": "Inhibitor of Bruton tyrosine kinase", "gene_name": "Ibtk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAATPDCTSKCRSLKHALDVLSVVTKGSESQIKSFLARYCYNAATVKDAFGRNAGHLASSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSVFYGHIDCVWSLLKHGVSLYMQDKEGLSPLDLLMKDRPTHVVFKDTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPPASCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICVLAMDGAGRVFCWRSISSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKNSEKKADILPNLHHSSSDVSCVPDTNSVYERIRLEKLPFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNRHFPAHKYILAVRSDFFQKLFLSDGSSLELTDVYQKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDLLTHGFKPRMIVKRKAEDCEGSPDSHLHTVNCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGDDDPVRMLQSVAKKFGLSNLSSRLEGVRLENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFSCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQSEILKVILDYLYTDEAVVIKESQNVDFVCSVLVVADQLLITRLKEICEVALTENLTLKNAAMLLEFAALYNAGQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISSMQVEDGEVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYTLSDVIQSPPSAGLLKSAKTNSVESLPELLTSDSEGSYAGVASPRDLQSPDFTAGFHSDKVEGKAKPYVNGIPPPCTREDVKPWEKSPTTKSAPQFIPSNRVDTAASSSWLAGSCSPVSPPVVDLRTIMETEENRQKYGAAPKSNLGKIISHGIKLSQKQRKMIALTTKENNSGTNSMEAILTAPSKSPKPANAWAPLHSPLSRSFRDFLLEEKKPVPGYGSGDHVKKVCFKGTENSPALNVARCSTHGTPGLESNHVSDFPLLDSPNPWQSSSLAASPAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPEEFVVVERAPQGPLAVPMWNKHGC", "length": 1352 }, "evidence": [ { "id": "A0A3Q2U7Z3", "url": "https://omabrowser.org/oma/group/A0A3Q2U7Z3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2D0-1", "protein_name": "Inhibitor of Bruton tyrosine kinase", "gene_name": "IBTK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPMPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCYNAATIKDVFGRNALHLVSSCGKKGVLDWLIQKGVDLLVKDKESGWTALHRSIFYGHIDCVWSLLKHGVSLYIQDKEGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGATVCVTTRGDIYLLADYQCKKMASKQLNLKKVLVSGGHMEYKVDPEHLKENGGQKICILAMDGAGRVFCWRSVNSSLKQCRWAYPRQVFISDIALNRNEILFVTQDGEGFRGRWFEEKRKSSEKKEILSNLHNSSSDVSYVSDINSVYERIRLEKLTFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPAVSSSSFFEEFGKLLREADEMDSIHDVTFQVGNRLFPAHKYILAVHSDFFQKLFLSDGNTSEFTDIYQKDEDSAGCHLFVVEKVHPDMFEYLLQFIYTDTCDFLTHGFKPRIHLNKNPEEYQGTLNSHLNKVNFHEDDNQKSAFEVYKSNQAQTVSERQKSKPKSCKKGKNIREDDPVRMLQTVAKKFDFSNLSSRLDGVRFENEKINVIAKNTGNKLKLSQKKCSFLCDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIHSDILKVILDYLYTDEAVVIKESQNVDFICSVLVVADQLLITRLKEICEVALTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFIGLNMAALLEARSLDVLSDGVLKDLSEFYRKMIPAMDRRVITPYQDGPDISYLEVEDGDIFLKEEINMEQNHSETMFKKAKTKAKKKPRKRSDSSGGYNLSDIIQSPSSTGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTTGFHSDKIEAKVKPYVNGTSPVYSREDLKPWEKSPILKISAPQPIPSNRIDTTSSASWVAGSFSPVSPPVVDLRTIMEIEESRQKCGATPKSHLGKTVSHGVKLSQKQRKMIALTTKENNSGMNSMETVLFTPSKAPKPVNAWASSLHSVSSKSFRDFLLEEKKSVTSHSSGDHVKKVSFKGIENSQAPKIVRCSTHGTPGPEGNHISDLPLLDSPNPWLSSSVTAPSMVAPVTFASIVEEELQQEAALIRSREKPLALIQIEEHAIQDLLVFYEAFGNPEEFVIVERTPQGPLAVPMWNKHGC", "length": 1353 }, "evidence": [ { "id": "A0A3Q2U7Z3", "url": "https://omabrowser.org/oma/group/A0A3Q2U7Z3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" }, { "name": "protein tyrosine kinase inhibitor activity", "id": "GO:0030292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030292", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1100, "end_pos": 1102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1169, "end_pos": 1171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U7Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z3" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 565, "end_pos": 645, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1187 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1100, "end_pos": 1102 }, { "start_pos": 1143, "end_pos": 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"start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A3Q2U8D9", "uniprot_id": "A0A3Q2U8D9_CHICK", "mass": { "chemical_mass": 59053.0, "monoisotopic_mass": 59053.0 }, "refseq": {}, "gene_names": [ { "name": "DNAJC11", "type": "recommended", "evidence": [ { "id": "A0A3Q2U8D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9" } ] } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member C11", "type": "synonym", "evidence": [ { "id": "A0A3Q2U8D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8D9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9", "locus": { "chromosome": "21", "start_pos": 543879, "end_pos": 528995, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018917", "url": "https://www.ensembl.org/id/ENSGALG00010018917" } ] } } ], "crossref": [ { "id": "A0A3Q2U8D9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8D9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000627", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000627", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428173", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428173", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U8D9", "url": "https://www.orthodb.org/?gene=A0A3Q2U8D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44157:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44157:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U8D9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U8D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQTRAIYDIYGRRGLEMEGWEVVERKRTPAEIREEFERLQREREERRLQQRTNPKGTISVGIDATDLFDRYDEEYEDVQGSSFPQIEINKMHISQSIEAPLTSTDTAILSGNLSTQNGNGGGSINLALRRVTSAKGWGELEFGAGDLQGPLFGLKIFRNLTPRCFITTNCALQFSSRGVRPGLTTVLARNLDKNTMGYLQWRWGIQSAMNTSIVRDTKTSHFTVALQLGIPHSFMMVSYQHKFQDEDQTRIKGSLKAGFFGTIVEYGAERKISRHSILGATVSVGVPQGVSLKIKLNRASQTYFFPVHLTDQLLPSAVFYATVGPLVIYFAMHRLIIKPYLRAQKERELEKQRESTASDILQKKQEAEAAVRLMQESVRRIIEAEEARMGLIVVNAWYGKFVNDNSRKNEKVKVIDVTVPLQCLVKDSKLILTEASKVGLPGFYDPCVGEEKSLKVLYQFRGVLHQVMSADNEALRIPKQSHRIDADG", "length": 521, "header": "tr|A0A3Q2U8D9-1|A0A3Q2U8D9_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C11 OS=Gallus gallus OX=9031 GN=DNAJC11 PE=1 SV=1 CANONICAL=A0A3Q2U8D9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U8D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9/entry", "sequence": { "sequence": "MLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQTRAIYDIYGRRGLEMEGWEVVERKRTPAEIREEFERLQREREERRLQQRTNPKGTISVGIDATDLFDRYDEEYEDVQGSSFPQIEINKMHISQSIEAPLTSTDTAILSGNLSTQNGNGGGSINLALRRVTSAKGWGELEFGAGDLQGPLFGLKIFRNLTPRCFITTNCALQFSSRGVRPGLTTVLARNLDKNTMGYLQWRWGIQSAMNTSIVRDTKTSHFTVALQLGIPHSFMMVSYQHKFQDEDQTRIKGSLKAGFFGTIVEYGAERKISRHSILGATVSVGVPQGVSLKIKLNRASQTYFFPVHLTDQLLPSAVFYATVGPLVIYFAMHRLIIKPYLRAQKERELEKQRESTASDILQKKQEAEAAVRLMQESVRRIIEAEEARMGLIVVNAWYGKFVNDNSRKNEKVKVIDVTVPLQCLVKDSKLILTEASKVGLPGFYDPCVGEEKSLKVLYQFRGVLHQVMSADNEALRIPKQSHRIDADG", "length": 521, "header": "tr|A0A3Q2U8D9-1|A0A3Q2U8D9_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C11 OS=Gallus gallus OX=9031 GN=DNAJC11 PE=1 SV=1 CANONICAL=A0A3Q2U8D9-1" }, "locus": { "chromosome": "21", "start_pos": 542420, "end_pos": 530920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045765.1", "url": "https://www.ensembl.org/id/ENSGALT00010045765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027283.1", "url": "https://www.ensembl.org/id/ENSGALP00010027283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428173", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428173", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "SAM complex", "id": "GO:0001401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001401", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8D9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9" } ], "pmid": "" }, { "name": "MICOS complex", "id": "GO:0061617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061617", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8D9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8D9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cristae 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"name": "CREG2", "type": "synonym", "evidence": [ { "id": "XP_001233982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233982" } ] } ], "protein_names": [ { "name": "Cellular repressor of E1A stimulateds 2", "type": "synonym", "evidence": [ { "id": "A0A3Q2U8T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8T7/entry#names_and_taxonomy" } ] }, { "name": "protein CREG2", "type": "synonym", "evidence": [ { "id": "XP_001233982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001233982.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U8T7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8T7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CREG2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U8T7", "locus": { "chromosome": "1", "start_pos": 133594556, "end_pos": 133610087, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013520", "url": "https://www.ensembl.org/id/ENSGALG00010013520" } ] } } ], "crossref": [ { "id": "A0A3Q2U8T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U8T7", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"evidence": [ { "id": "A0A3Q2U8T7", "url": "https://omabrowser.org/oma/group/A0A3Q2U8T7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1STG3-1", "protein_name": "Cellular repressor of E1A stimulateds 2", "gene_name": "CREG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRRGQRPGHCLCWLLCCVLLSPAAGYVIVSSVSWAVTNEVDEELDSASTEETLPTMLEDSGSIWQRSFPASAHKEDAHLPPPVGAAGARPPPEPPGMFSYRREGGARLRPGTARFLAHASAWGCLATVSAHEKMPGLPFGNCLPISDGPFNNSTGIPFFYVTPKDPVVADLLKNPMASLLLPESEGEFCRKNIVDPEDPRCARLTLTGQMVAVSPEEVEFAKQAVFSRHPVMRKWPRQYEWFFMKLKIEHIWLQKWYGGVADISQEEYFKATPRKA", "length": 278 }, "evidence": [ { "id": "A0A3Q2U8T7", "url": "https://omabrowser.org/oma/group/A0A3Q2U8T7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BGC9-1", "protein_name": "Protein CREG2", "gene_name": "Creg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938764" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYSLTR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6", "locus": { "chromosome": "1", "start_pos": 168795646, "end_pos": 168785413, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003958", "url": "https://www.ensembl.org/id/ENSGALG00010003958" } ] } } ], "crossref": [ { "id": "ENSGALG00000050065", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000050065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15157", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15157", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428071", "url": "https://www.ncbi.nlm.nih.gov/gene/428071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428071", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCTIIVC", "url": "https://omabrowser.org/oma/group/FCTIIVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9B6", "url": "https://www.orthodb.org/?gene=A0A3Q2U9B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-391906", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSSEMMLNDSSTNSSFNCSTDAFKQVIYPIVYLLIFFLGSVGNSLSIYVFLQPSQRKTSVNTYMQNLAVSDLMFVSTLPFRATYYLLGSQWVFGDILCRIMTYTMYVNMYCSIYFLTVLSVVRFTAIVYPFKSWKVSNMKYAKIMCAVIWVFVLAASSPLLSKAIAGYENPAKCLDLHPSSTHRLLMMNSFVLVVGFILPFCTIIVCYIFAIRALLKSKTPQRKKAVCHKKALSTIIITLILFLLCFLPYHILRTVYLVFGGCSPDNLFVHKAQVVSLCLAATNSCLDPVLYYFAAENFKARIRSLYRR", "length": 310, "header": "tr|A0A3Q2U9B6-1|A0A3Q2U9B6_CHICK Isoform 1 of Cysteinyl leukotriene receptor 2 OS=Gallus gallus OX=9031 GN=CYSLTR2 PE=4 SV=1 CANONICAL=A0A3Q2U9B6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U9B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6/entry", "sequence": { "sequence": "MNSSEMMLNDSSTNSSFNCSTDAFKQVIYPIVYLLIFFLGSVGNSLSIYVFLQPSQRKTSVNTYMQNLAVSDLMFVSTLPFRATYYLLGSQWVFGDILCRIMTYTMYVNMYCSIYFLTVLSVVRFTAIVYPFKSWKVSNMKYAKIMCAVIWVFVLAASSPLLSKAIAGYENPAKCLDLHPSSTHRLLMMNSFVLVVGFILPFCTIIVCYIFAIRALLKSKTPQRKKAVCHKKALSTIIITLILFLLCFLPYHILRTVYLVFGGCSPDNLFVHKAQVVSLCLAATNSCLDPVLYYFAAENFKARIRSLYRR", "length": 310, "header": "tr|A0A3Q2U9B6-1|A0A3Q2U9B6_CHICK Isoform 1 of Cysteinyl leukotriene receptor 2 OS=Gallus gallus OX=9031 GN=CYSLTR2 PE=4 SV=1 CANONICAL=A0A3Q2U9B6-1" }, "locus": { "chromosome": "1", "start_pos": 168792270, "end_pos": 168791341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009152.1", "url": "https://www.ensembl.org/id/ENSGALT00010009152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005406.1", "url": "https://www.ensembl.org/id/ENSGALP00010005406.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428071", "resource": "KEGG Pathway" }, { "id": "R-GGA-391906", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "resource": "Reactome", "description": "Leukotriene receptors" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HR84-1", "protein_name": "Cysteinyl leukotriene receptor 2", "gene_name": "Cysltr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPTGAFSNNSDRNCTIESFKKEFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYYFRESNWIFGDLACRIMSYSLYVNMYTSIYFLTVLSVVRFLATVHPFQQLHVTSVRSAWILCGVIWIFIMASSAMLLKNGYEKKDNIILCLELTPQKFSKLLIMNHIALVAGFLLPFVTLTICYLLIIRVLLKVEIPESGLRASHRKALITIIIAMLIFLLCFLPYHALRTLHLVTWNADSCGDEIHKAMVITLALAATNSCFNPFLYYFAGENFKDRLRDVFSKDRLQKSKAKCGLPFCV", "length": 322 }, "evidence": [ { "id": "A0A3Q2U9B6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9B6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q920A1-1", "protein_name": "Cysteinyl leukotriene receptor 2", "gene_name": "Cysltr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVTGTPSSYSNRNCTIENFKKEFYPIIYLIIFFWGALGNGFSIYVFLQTCKKSTSVNVFMLNLATSDFLFISTLPFRADYYFRGSNWIFGDLACRVMSYSLYVNMYTSIYFLTVLSVVRFLATVHPFRMFHVTSVRSAWILCGIIWVFIMASSALLLVNGQEEKDNIISCLELSPQKFKSLLIMNHIAVAVGFLLPFLTLTVCYLLIIRILLKAEIPESGPRAAHRKALTTIVIAMITFLLCFLPYHALRTLHLVTWDKDSCGDVLHKATVITLTMAAANSCFNPFLYYFAGENFKARLRAIFSKVHL", "length": 309 }, "evidence": [ { "id": "A0A3Q2U9B6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9B6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924T9-1", "protein_name": "Cysteinyl leukotriene receptor 2", "gene_name": "Cysltr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL", "length": 309 }, "evidence": [ { "id": "A0A3Q2U9B6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9B6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NS75-1", "protein_name": "Cysteinyl leukotriene receptor 2", "gene_name": "CYSLTR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV", "length": 346 }, "evidence": [ { "id": "A0A3Q2U9B6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9B6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteinyl leukotriene receptor activity", "id": "GO:0001631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001631", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9B6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2U9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9B6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U9J5-1", "uniprot_ac": "A0A3Q2U9J5", "uniprot_id": "A0A3Q2U9J5_CHICK", "mass": { "chemical_mass": 11120.0, "monoisotopic_mass": 11120.0 }, "refseq": { "ac": "XP_046776644", "name": "neuropeptide S", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776644" }, "gene_names": [ { "name": "NPS", "type": "recommended", "evidence": [ { "id": "A0A3Q2U9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ] }, { "name": "NPS", "type": "synonym", "evidence": [ { "id": "XP_046776644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776644" } ] } ], "protein_names": [ { "name": "Neuropeptide S", "type": "synonym", "evidence": [ { "id": "A0A3Q2U9J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide S", "type": "synonym", "evidence": [ { "id": "XP_046776644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776644" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046776644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776644" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPS", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5", "locus": { "chromosome": "6", "start_pos": 33986003, "end_pos": 33982915, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002611", "url": "https://www.ensembl.org/id/ENSGALG00010002611" } ] } } ], "crossref": [ { "id": "A0A3Q2U9J5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858023", "url": "https://www.ncbi.nlm.nih.gov/gene/100858023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MFVCSGY", "url": "https://omabrowser.org/oma/group/MFVCSGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9J5", "url": "https://www.orthodb.org/?gene=A0A3Q2U9J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36679:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36679:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14993", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14993", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046776644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776644", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISLCRLNLLFILWMSAMFVCSGYPVGPSMSSNPFYLNCQLYGKSDYCLVLLNSCLAKVGRSEEVALLEPHLEMPFNKRSFRNGVGSGIKKTSFRRAKS", "length": 99, "header": "tr|A0A3Q2U9J5-1|A0A3Q2U9J5_CHICK Isoform 1 of Neuropeptide S OS=Gallus gallus OX=9031 GN=NPS PE=4 SV=1 CANONICAL=A0A3Q2U9J5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5/entry", "sequence": { "sequence": "MISLCRLNLLFILWMSAMFVCSGYPVGPSMSSNPFYLNCQLYGKSDYCLVLLNSCLAKVGRSEEVALLEPHLEMPFNKRSFRNGVGSGIKKTSFRRAKS", "length": 99, "header": "tr|A0A3Q2U9J5-1|A0A3Q2U9J5_CHICK Isoform 1 of Neuropeptide S OS=Gallus gallus OX=9031 GN=NPS PE=4 SV=1 CANONICAL=A0A3Q2U9J5-1" }, "locus": { "chromosome": "6", "start_pos": 33985139, "end_pos": 33982979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006035.1", "url": "https://www.ensembl.org/id/ENSGALT00010006035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003761.1", "url": "https://www.ensembl.org/id/ENSGALP00010003761.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "P0C0P6-1", "protein_name": "Neuropeptide S", "gene_name": "NPS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISSVKLNLILVLSLSTMHVFWCYPVPSSKVSGKSDYFLILLNSCPTRLDRSKELAFLKPILEKMFVKRSFRNGVGTGMKKTSFQRAKS", "length": 89 }, "evidence": [ { "id": "A0A3Q2U9J5", "url": "https://omabrowser.org/oma/group/A0A3Q2U9J5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C0P7-1", "protein_name": "Neuropeptide S", "gene_name": "Nps", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIGSLKLNLILALSLSVVHVIWSYPVLSSKVPGKPDYFLILLSTCPARLEGSDGLAFLKPILEKTSMKRSFRNGVGSGVKKTSFRRAKQ", "length": 89 }, "evidence": [ { "id": "A0A3Q2U9J5", "url": "https://omabrowser.org/oma/group/A0A3Q2U9J5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0P8-1", "protein_name": "Neuropeptide S", "gene_name": "Nps", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIGSLKLSFVLALSLSVMHVLWCYPVLSSKVPGKPDYFLILLSSCPARLEGSDRLAFLKPILEKTSMKRSFRNGVGSGAKKTSFRRAKQ", "length": 89 }, "evidence": [ { "id": "A0A3Q2U9J5", "url": "https://omabrowser.org/oma/group/A0A3Q2U9J5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "positive regulation of synaptic transmission, GABAergic", "id": "GO:0032230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032230", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "positive regulation of synaptic transmission, glutamatergic", "id": "GO:0051968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051968", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "positive regulation of action potential", "id": "GO:0045760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045760", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" }, { "name": "positive regulation of cAMP/PKA signal transduction", "id": "GO:0141163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141163", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neuropeptide activity", "id": "GO:0160041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160041", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9J5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U9J5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 99, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U9J5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9J5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U9M6-1", "uniprot_ac": "A0A3Q2U9M6", "uniprot_id": "A0A3Q2U9M6_CHICK", "mass": { "chemical_mass": 27877.0, "monoisotopic_mass": 27877.0 }, "refseq": { "ac": "NP_001264766", "name": "BTB/POZ domain-containing protein KCTD14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766" }, "gene_names": [ { "name": "KCTD14", "type": "recommended", "evidence": [ { "id": "A0A3Q2U9M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6" } ] }, { "name": "KCTD14", "type": "synonym", "evidence": [ { "id": "NP_001264766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD14", "type": "synonym", "evidence": [ { "id": "NP_001264766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766" } ] }, { "name": "Potassium channel tetramerization domain containing 14", "type": "synonym", "evidence": [ { "id": "A0A3Q2U9M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6/entry#names_and_taxonomy" } ] }, { "name": "potassium channel tetramerisation domain containing 14", "type": "synonym", "evidence": [ { "id": "NP_001264766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01026281.1, BX950733.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000028.1. On Apr 21, 2013 this sequence version replaced XP_003640645.1. Sequence Note: This RefSeq record was created with transcript data from different strains to make the sequence consistent with the transcript data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264766", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9M6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6", "locus": { "chromosome": "1", "start_pos": 192766473, "end_pos": 192762138, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001987", "url": "https://www.ensembl.org/id/ENSGALG00010001987" } ] } } ], "crossref": [ { "id": "A0A3Q2U9M6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9M6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000055000", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000055000", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18371", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18371", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419029", "url": "https://www.ncbi.nlm.nih.gov/gene/419029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419029", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVGGEMY", "url": "https://omabrowser.org/oma/group/NVGGEMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9M6", "url": "https://www.orthodb.org/?gene=A0A3Q2U9M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264766", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264766", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9M6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSISSEHKPLGKQVTGSLPTLPPIVELNVGGEMYTTTLSTLKKHPGSKLAEMFTGQHKLRTDSKGRIFIDRPGTYFKYILEYLRSNKVPTQCIQDVYKEALFYDIEPLIKQLEDSPQIFGERVARKQFLARVPNYSENIELMIRIARAEAVASRYSRVIICVVRTEEDAARCQDALNSLDMDKKSVVKFGPWKAAPSIYDLLDCIQMDVKDKGYTISLQAHVAEKGFRFKSQDFFHIIQFTWW", "length": 243, "header": "tr|A0A3Q2U9M6-1|A0A3Q2U9M6_CHICK Isoform 1 of Potassium channel tetramerization domain containing 14 OS=Gallus gallus OX=9031 GN=KCTD14 PE=1 SV=1 CANONICAL=A0A3Q2U9M6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U9M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6/entry", "sequence": { "sequence": "MSISSEHKPLGKQVTGSLPTLPPIVELNVGGEMYTTTLSTLKKHPGSKLAEMFTGQHKLRTDSKGRIFIDRPGTYFKYILEYLRSNKVPTQCIQDVYKEALFYDIEPLIKQLEDSPQIFGERVARKQFLARVPNYSENIELMIRIARAEAVASRYSRVIICVVRTEEDAARCQDALNSLDMDKKSVVKFGPWKAAPSIYDLLDCIQMDVKDKGYTISLQAHVAEKGFRFKSQDFFHIIQFTWW", "length": 243, "header": "tr|A0A3Q2U9M6-1|A0A3Q2U9M6_CHICK Isoform 1 of Potassium channel tetramerization domain containing 14 OS=Gallus gallus OX=9031 GN=KCTD14 PE=1 SV=1 CANONICAL=A0A3Q2U9M6-1" }, "locus": { "chromosome": "1", "start_pos": 192765267, "end_pos": 192762222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004518.1", "url": "https://www.ensembl.org/id/ENSGALT00010004518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002747.1", "url": "https://www.ensembl.org/id/ENSGALP00010002747.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RPG8-1", "protein_name": "Potassium channel tetramerisation domain containing 14", "gene_name": "Kctd14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLPANQIKEPGKQSQPAKSLKEPSQEALPVNLLKESSQESRILCPDPAIVVELNVGGQFYTTTMGTLMKHPGSKFSEILSRSARHYKDAQGRFFIDRPGTYFGLLLDYLRTGQVPTEYVPEVYQEAKFYQIHLLVKILEDMPQIFGEQVARTQFLMGVPNYRENLEVLLHLARAEAVAMRSSKVVVCVVRTEEEDAKCVEPLHILEAKKTPVVKFGPWKAGPMTEDFVCCLEKDIRAKGYKVTSQRYHLSRDPYTCFWIFVFTWW", "length": 266 }, "evidence": [ { "id": "A0A3Q2U9M6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9M6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A287AC80-1", "protein_name": "Potassium channel tetramerization domain containing 14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSLVSAPGSRPLGRAAPTAGPRRESPVVELNVGGEFYTTTLGTLRKIPGSKLAEMFSSSAKACTDAEGRFFIDRPGTYFGPILEYLRSGQLPRQHIPEVYREAQYYEIEPLVKLLEDMPQIFGEQVARKQFLLRVPGYSENLQLMVRLARAEAVAARYSEVLVCVVHNEKDDANCVDTLRLLEADKRSVVKFGPWKAAPTIDHLLDCVKMDIKAQGYQVQCSKHLGLPANYFYTFCFTWW", "length": 241 }, "evidence": [ { "id": "A0A3Q2U9M6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9M6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8RRJ7-1", "protein_name": "BTB/POZ domain-containing protein KCTD14", "gene_name": "kctd14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLPDYKTIGKQSSAPVQSKSQVVHLNIGGHVFSTTLGTIRKFPNSTLAELINGSSKRMDSEGRYFIDRDGTLFTHILEYLRTEKLPCEHLQEVHKEAIYYDIKPLVKAIEETPQFFGETVGRQQFLARVPNYRENLEVIVRVARAEAIASRHSNIIVCVLRTEDDLSRYNDAIDSLDAPRESVVSFGPWKAPASVEDLLDCVKMDIEAKGYKVKIQAHSVDKGFLFKSYDFFYKLVFTWW", "length": 241 }, "evidence": [ { "id": "A0A3Q2U9M6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9M6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M0C4-1", "protein_name": "Potassium channel tetramerization domain containing 14", "gene_name": "Kctd14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLNSDPLFFLPLPPRCWNYRMSLPANQIKEPGKQFQPAKSLKEPSQESLPGNLLKEPSQESRILCPDPDIVVELNVGGQFYTTTMGTLMKHPGSKFSEILSRSAKHYKDAQGRFFIDRPGTYFGPLLDYLRTGQVPTEYIPEVYQEAKFYQIHPLVKLLEDKPQIFGEQVARMQFLMGVPNYRENLEVLLHLARAEAVAMRSSKVVVCVVRTEEDDAKCTEPLHILEAKKTPVVKFGPWKAGPVTEDFVYCLEKDIRAKGYTVASQRYHLSRDPYTCFWILVFTWW", "length": 287 }, "evidence": [ { "id": "A0A3Q2U9M6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9M6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQ13-1", "protein_name": "BTB/POZ domain-containing protein KCTD14", "gene_name": "KCTD14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFTWW", "length": 255 }, "evidence": [ { "id": "A0A3Q2U9M6", "url": "https://omabrowser.org/oma/group/A0A3Q2U9M6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9M6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U9M6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U9M6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9M6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2U9R7-1", "uniprot_ac": "A0A3Q2U9R7", "uniprot_id": "A0A3Q2U9R7_CHICK", "mass": { "chemical_mass": 48500.0, "monoisotopic_mass": 48500.0 }, "refseq": { "ac": "XP_015146982", "name": "ras association domain-containing protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146982" }, "gene_names": [ { "name": "RASSF8", "type": "recommended", "evidence": [ { "id": "A0A3Q2U9R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7" } ] }, { "name": "RASSF8", "type": "synonym", "evidence": [ { "id": "XP_015146982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146982" } ] } ], "protein_names": [ { "name": "Ras association domain family member 8", "type": "synonym", "evidence": [ { "id": "A0A3Q2U9R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7/entry#names_and_taxonomy" } ] }, { "name": "ras association domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "XP_015146982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9R7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7", "locus": { "chromosome": "1", "start_pos": 67653703, "end_pos": 67578462, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014328", "url": "https://www.ensembl.org/id/ENSGALG00010014328" } ] } } ], "crossref": [ { "id": "A0A3Q2U9R7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9R7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054273", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054273", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16134", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16134", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418210", "url": "https://www.ncbi.nlm.nih.gov/gene/418210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418210", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEIRYWE", "url": "https://omabrowser.org/oma/group/VEIRYWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U9R7", "url": "https://www.orthodb.org/?gene=A0A3Q2U9R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNP4", "url": "https://www.orthodb.org/?gene=A0A8V0YNP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15286:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15286:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9R7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQNDKAMKRREPKRKSLTFTGGAKGLMDIFGKSKESEFKQKVLNNCKTTADELKKLIHLQTEKLQCIEKQLESNEAEIRYWEQKYNASLEEEILKLEQKIKRNEVEIEEEEFWENELQIEQENEKQLKEQLQEMRQRILECEGKLKDYMSQIHNMESGLEAEKLHREVQESQVNEEEVKEKIEKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDREQELEQLTKELRQVNLQQFIQQTGTKVTVLPADPVEVEAPPVELEREPTFQSGSLKRPGSSRQLPSNLRILQNPLSSGFNPEGIYV", "length": 419, "header": "tr|A0A3Q2U9R7-1|A0A3Q2U9R7_CHICK Isoform 1 of Ras association domain family member 8 OS=Gallus gallus OX=9031 GN=RASSF8 PE=4 SV=1 CANONICAL=A0A3Q2U9R7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7/entry", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQNDKAMKRREPKRKSLTFTGGAKGLMDIFGKSKESEFKQKVLNNCKTTADELKKLIHLQTEKLQCIEKQLESNEAEIRYWEQKYNASLEEEILKLEQKIKRNEVEIEEEEFWENELQIEQENEKQLKEQLQEMRQRILECEGKLKDYMSQIHNMESGLEAEKLHREVQESQVNEEEVKEKIEKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDREQELEQLTKELRQVNLQQFIQQTGTKVTVLPADPVEVEAPPVELEREPTFQSGSLKRPGSSRQLPSNLRILQNPLSSGFNPEGIYV", "length": 419, "header": "tr|A0A3Q2U9R7-1|A0A3Q2U9R7_CHICK Isoform 1 of Ras association domain family member 8 OS=Gallus gallus OX=9031 GN=RASSF8 PE=4 SV=1 CANONICAL=A0A3Q2U9R7-1" }, "locus": { "chromosome": "1", "start_pos": 67652454, "end_pos": 67638194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034518.1", "url": "https://www.ensembl.org/id/ENSGALT00010034518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020276.1", "url": "https://www.ensembl.org/id/ENSGALP00010020276.1" } ] } }, { "isoform_ac": "A0A8V0YNP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP4/entry", "sequence": { "sequence": "MRVKSDADVRIVAREKEGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQNDKAMKRREPKRKSLTFTGGAKGLMDIFGKSKESEFKQKVLNNCKTTADELKKLIHLQTEKLQCIEKQLESNEAEIRYWEQKYNASLEEEILKLEQKIKRNEVEIEEEEFWENELQIEQENEKQLKEQLQEMRQRILECEGKLKDYMSQIHNMESGLEAEKLHREVQESQVNEEEVKEKIEKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDREQELEQLTKELRQVNLQQFIQQTGTKVTVLPADPVEVEAPPVELEREPTFQSGSLKRPGSSRQLPSNLRILQNPLSSGFNPEGIYV", "length": 402, "header": "tr|A0A8V0YNP4-1|A0A3Q2U9R7_CHICK Computationally mapped isoform of Ras association domain family member 8 OS=Gallus gallus OX=9031 GN=RASSF8 PE=4 SV=1 CANONICAL=A0A3Q2U9R7-1" }, "locus": { "chromosome": "1", "start_pos": 67652454, "end_pos": 67629510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034514.1", "url": "https://www.ensembl.org/id/ENSGALT00010034514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020274.1", "url": "https://www.ensembl.org/id/ENSGALP00010020274.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418210", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0F4-1", "protein_name": "Ras association domain family member 8", "gene_name": "Rassf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQVDKSIRRREPKRKSLTFTGGAKGLTDIFGKGKETEFRQKVLSNCRATAEELTRLIRLQTGKLQAIEKQLESSEAEIRFWEQKYSCSLEEEIVRLEQRIKRNDVEIEEEEFWENELQIEQENEKQLQDQLEEMRQKVADCEGRLKDYLAQIHTMESGLQAEKLHREVQEAQVNEEEVKGKIEKVKGEVDLQGQQSLRLENGIRAVARSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQADIETEAPFPSGSLKRPGSSRQLPSNLRILQNPVSSGFNPEGIYV", "length": 419 }, "evidence": [ { "id": "A0A3Q2U9R7", "url": "https://omabrowser.org/oma/group/A0A3Q2U9R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SG73-1", "protein_name": "Ras association domain family member 8", "gene_name": "RASSF8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKTIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKELESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECESKLKDYLAQIQTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVRGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEVEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISAGFNPEGIYV", "length": 419 }, "evidence": [ { "id": "A0A3Q2U9R7", "url": "https://omabrowser.org/oma/group/A0A3Q2U9R7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HXQ4-1", "protein_name": "Ras association domain-containing protein 8 isoform X1", "gene_name": "Rassf8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQVDKSMKRREPKRKSLTFTGGAKGLMDIFGKGKEAEFRQKVLSNCRSTAEELRRLIRLQTDKLLAIEQQLESSETEIRFWEQKYNSSLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLQDQLDEIRQKVTDCDSKLKDYLAQIQKMESGLEAEKLHLEVEEAQVNEEEMKGKIEKVRGEMDLQGQQSLRLENGIRAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQADIETETPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV", "length": 419 }, "evidence": [ { "id": "A0A3Q2U9R7", "url": "https://omabrowser.org/oma/group/A0A3Q2U9R7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CJ96-1", "protein_name": "Ras association domain-containing protein 8", "gene_name": "Rassf8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQADKSIRRREPKRKSLTFTGGAKGLTDIFGKGKETEFRQKVLSNCRATAEELKRLIRLQTGKLQAIEKQLESSEAEIRFWEQKYSCSLEEEIVRLEQRIKRNDVEIEEEEFWENELQIEQENEKQLQDQLEEIRQKVTDCEGRLKDYLAQIHTMESGLQAEKLHREVQEAQVNEEEVKGKIEKVKGEMDLQGQQSLRLENGIRAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQADIETEAPFQSGSLKRPGSSRQLPSNLRILQNPVSSGFNPEGIYV", "length": 419 }, "evidence": [ { "id": "A0A3Q2U9R7", "url": "https://omabrowser.org/oma/group/A0A3Q2U9R7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NHQ8-1", "protein_name": "Ras association domain-containing protein 8", "gene_name": "RASSF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV", "length": 419 }, "evidence": [ { "id": "A0A3Q2U9R7", "url": "https://omabrowser.org/oma/group/A0A3Q2U9R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U9R7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2U9R7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 419, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2U9R7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2U9R7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UAQ0-1", "uniprot_ac": "A0A3Q2UAQ0", "uniprot_id": "A0A3Q2UAQ0_CHICK", "mass": { "chemical_mass": 73775.0, "monoisotopic_mass": 73775.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100859084", "type": "recommended", "evidence": [ { "id": "A0A3Q2UAQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q2UAQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859084", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0", "locus": {} } ], "crossref": [ { "id": "A0A3Q2UAQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000051428", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000051428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAQ0", "url": "https://www.orthodb.org/?gene=A0A3Q2UAQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQENYENVISLAEEIAISWPRITAFAESQRRRGMVPGTDADCDPHPTEAAPPAPPGSGSGVGGTPDLRRQLGLLLQTAGRCQVERMLRELVREQGPGGARRGRRRATRSPRDGGAGAEDASPNGADPSPSPSPSPSQPEPVAKTQRRSTKKSEPTPAPCAECARGAATKLRCCPGCSRRCRTAVAAEKPHRCVECGKGFSRGSNLTQHRRIHTGERPHRCGDCGKGFIQRSDLERHRRVHTGERPYPCGDCGKSFSVSSHLDRHRRTHAGAVVGARTTHRPVPVNDVGSSAPHRCPECGKGFGQRSALSKHRKTHGGERPHRCGDCGKSFSRGSNLTQHRRIHTGERPFACGDCGKGFIQRSDLERHRRVHTGERPYQCGECGKSFSVSSHLERHRKIHVAERCHEHVEEFLAAHRHGRAYKCGECGRCFGQGAALLKHQRAHAGGRPPPHQCSHQSDGDGDGAVPPAPPEKPYKCGDCGKGFGQRSALVKHRRIHTGEKPYACGDCGKGFIQKSDLTIHRRMHTGEKPYRCGECGKCFSVSSNLLTHRRTHLGEKPYGCPECGKSFIQRSELTIHRRVHTGEKPYACPACGKCFSRSSHLNRHRRTHSGEKTPAPPPADLRADAGPPPAPPPFPAAGPPLPLSPLELPWALSFPARAFVPPGFPPPAGAAPGAPAPSLAE", "length": 681, "header": "tr|A0A3Q2UAQ0-1|A0A3Q2UAQ0_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100859084 PE=3 SV=1 CANONICAL=A0A3Q2UAQ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UAQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0/entry", "sequence": { "sequence": "MQENYENVISLAEEIAISWPRITAFAESQRRRGMVPGTDADCDPHPTEAAPPAPPGSGSGVGGTPDLRRQLGLLLQTAGRCQVERMLRELVREQGPGGARRGRRRATRSPRDGGAGAEDASPNGADPSPSPSPSPSQPEPVAKTQRRSTKKSEPTPAPCAECARGAATKLRCCPGCSRRCRTAVAAEKPHRCVECGKGFSRGSNLTQHRRIHTGERPHRCGDCGKGFIQRSDLERHRRVHTGERPYPCGDCGKSFSVSSHLDRHRRTHAGAVVGARTTHRPVPVNDVGSSAPHRCPECGKGFGQRSALSKHRKTHGGERPHRCGDCGKSFSRGSNLTQHRRIHTGERPFACGDCGKGFIQRSDLERHRRVHTGERPYQCGECGKSFSVSSHLERHRKIHVAERCHEHVEEFLAAHRHGRAYKCGECGRCFGQGAALLKHQRAHAGGRPPPHQCSHQSDGDGDGAVPPAPPEKPYKCGDCGKGFGQRSALVKHRRIHTGEKPYACGDCGKGFIQKSDLTIHRRMHTGEKPYRCGECGKCFSVSSNLLTHRRTHLGEKPYGCPECGKSFIQRSELTIHRRVHTGEKPYACPACGKCFSRSSHLNRHRRTHSGEKTPAPPPADLRADAGPPPAPPPFPAAGPPLPLSPLELPWALSFPARAFVPPGFPPPAGAAPGAPAPSLAE", "length": 681, "header": "tr|A0A3Q2UAQ0-1|A0A3Q2UAQ0_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100859084 PE=3 SV=1 CANONICAL=A0A3Q2UAQ0-1" }, "locus": { "chromosome": "MU179258.1", "start_pos": 72960, "end_pos": 67149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000656.1", "url": "https://www.ensembl.org/id/ENSGALT00010000656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000372.1", "url": "https://www.ensembl.org/id/ENSGALP00010000372.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UAQ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UAQ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAQ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2UAQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAQ0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 217, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 64, 155 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UAW2-1", "uniprot_ac": "A0A3Q2UAW2", "uniprot_id": "A0A3Q2UAW2_CHICK", "mass": { "chemical_mass": 89547.0, "monoisotopic_mass": 89547.0 }, "refseq": { "ac": "XP_025001521", "name": "rho GTPase-activating protein SYDE1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001521" }, "gene_names": [ { "name": "SYDE1", "type": "recommended", "evidence": [ { "id": "A0A3Q2UAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ] }, { "name": "SYDE1", "type": "synonym", "evidence": [ { "id": "XP_025001521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001521" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein SYDE1", "type": "recommended", "evidence": [ { "id": "A0A3Q2UAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2/entry#names_and_taxonomy" } ] }, { "name": "Synapse defective protein 1 homolog 1", "type": "synonym", "evidence": [ { "id": "A0A3Q2UAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein SYDE1", "type": "synonym", "evidence": [ { "id": "XP_025001521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001521" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052561.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025001521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001521" } ] }, { "annotation": "GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2#function" }, { "database": "UniProtKB", "id": "ARBA00057607", "url": "https://www.uniprot.org/uniprotkb/ARBA00057607#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYDE1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2", "locus": { "chromosome": "30", "start_pos": 201692, "end_pos": 209697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003479", "url": "https://www.ensembl.org/id/ENSGALG00010003479" } ] } } ], "crossref": [ { "id": "A0A3Q2UAW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000050416", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000050416", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "429892", "url": "https://www.ncbi.nlm.nih.gov/gene/429892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429892", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLQLDHT", "url": "https://omabrowser.org/oma/group/FLQLDHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAW2", "url": "https://www.orthodb.org/?gene=A0A3Q2UAW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46150:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46150:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025001521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPLLRRTFSRLRGRDRPRRKKSDGKEREHPQPGPDPLPAPEASPAPPEPSASRRQNWTRFSGRHPPPRAPLEGLEPTEQDATSSTPPSAADPPGEEPSELAEEADAAELCGPGRSPGHGAYLQSLERSSRHWVLSSGKAAGLDEAGGGTEMEVGTGGSEGEIWYNPIPEDEDPPKPCREDGKGMAESPGAHGMEEPAAGRSQACAKMPIPCVSSGAGLPSPSPPSSPGATKKGRSLSKVKSPGTVRRLSMKMKKLPELRRKLSLRSPRPRGQEGSTSPSDARKESSNVISRYHLDTSVASLPRSKAASKGGYLSDGDSPELPAKTGVLAEPEDGESGLDVAAFRPYSCGELPRGGQHISGLVSVHLYGVRDLKPPRAETREVFCVLQVDAANRARTALLPCKAAFLGLNHTFNLELEGAQLLKVMVFSWDPSSCRNRLCCHGSVLLPHIFRGSRAQQLAVQLQPRGVLFTKLTLVEQWEGPGEREPRVFGVELGQLVEREKTASKVPLLIQKCVAEIEKRGLKVVGLYRLCGSAAVKKELRDAFERDSAAVTLSEQLYPDINVITGILKDYLRELPTPLITPTLYHVVLEAMAKRPPRTPPAERDAVPLLDCLPDVEKATLTRLLDHLSLVASFHDFNRMNSQNIAVCFGPVLLTQSQEPRRGGTAAAVPRSYARSEDIASAVDFKRHIEVLHYLLQAWPAPRSPLTPQVPPTHPRQPPPRLDLPDTTVVARHRPRGPESPPSNRYAGDWSVCGHQLGGGYEEVTTGDNDSRAAHRRTLFVADFGLGDDPEAPFGPRLNLKDFDALILDLERELAKQINVCL", "length": 824, "header": "tr|A0A3Q2UAW2-1|A0A3Q2UAW2_CHICK Isoform 1 of Rho GTPase-activating protein SYDE1 OS=Gallus gallus OX=9031 GN=SYDE1 PE=4 SV=1 CANONICAL=A0A3Q2UAW2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2/entry", "sequence": { "sequence": "MAEPLLRRTFSRLRGRDRPRRKKSDGKEREHPQPGPDPLPAPEASPAPPEPSASRRQNWTRFSGRHPPPRAPLEGLEPTEQDATSSTPPSAADPPGEEPSELAEEADAAELCGPGRSPGHGAYLQSLERSSRHWVLSSGKAAGLDEAGGGTEMEVGTGGSEGEIWYNPIPEDEDPPKPCREDGKGMAESPGAHGMEEPAAGRSQACAKMPIPCVSSGAGLPSPSPPSSPGATKKGRSLSKVKSPGTVRRLSMKMKKLPELRRKLSLRSPRPRGQEGSTSPSDARKESSNVISRYHLDTSVASLPRSKAASKGGYLSDGDSPELPAKTGVLAEPEDGESGLDVAAFRPYSCGELPRGGQHISGLVSVHLYGVRDLKPPRAETREVFCVLQVDAANRARTALLPCKAAFLGLNHTFNLELEGAQLLKVMVFSWDPSSCRNRLCCHGSVLLPHIFRGSRAQQLAVQLQPRGVLFTKLTLVEQWEGPGEREPRVFGVELGQLVEREKTASKVPLLIQKCVAEIEKRGLKVVGLYRLCGSAAVKKELRDAFERDSAAVTLSEQLYPDINVITGILKDYLRELPTPLITPTLYHVVLEAMAKRPPRTPPAERDAVPLLDCLPDVEKATLTRLLDHLSLVASFHDFNRMNSQNIAVCFGPVLLTQSQEPRRGGTAAAVPRSYARSEDIASAVDFKRHIEVLHYLLQAWPAPRSPLTPQVPPTHPRQPPPRLDLPDTTVVARHRPRGPESPPSNRYAGDWSVCGHQLGGGYEEVTTGDNDSRAAHRRTLFVADFGLGDDPEAPFGPRLNLKDFDALILDLERELAKQINVCL", "length": 824, "header": "tr|A0A3Q2UAW2-1|A0A3Q2UAW2_CHICK Isoform 1 of Rho GTPase-activating protein SYDE1 OS=Gallus gallus OX=9031 GN=SYDE1 PE=4 SV=1 CANONICAL=A0A3Q2UAW2-1" }, "locus": { "chromosome": "30", "start_pos": 209158, "end_pos": 202778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008084.1", "url": "https://www.ensembl.org/id/ENSGALT00010008084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004841.1", "url": "https://www.ensembl.org/id/ENSGALP00010004841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429892", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429892", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZN9-1", "protein_name": "Rho GTPase-activating protein SYDE1", "gene_name": "Syde1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPLLRKTFSRLRGREKLPRKKSDAKDRGRPAQRSEPKPPEPEPRVLEGSQAGAEVPLSPETPRSPARGAYLQSLEPSSRRWVLGGAKPPEEISLGPRTPSSGEPAGEIWYNPIPEEDPRPPAPEPVGSQLASSEPEGPILQGAAPTSPPTKTSRTKSPGPARRLSMKMKKLPELRRRLSLRSTRTSRERERTAPAGSVISRYHLDSSVATPGQASVAGGTRSPRGGYLSDGDSPERPGGPPSPTAFRPYEVGPSARAPPAALWGRLSLHLYGLGGLRPTPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTIFRGCQAQQLAVRLEPQGLLYAKLTLSEQQEAPATVEPRVFGLPLQLLVEREQSPGQVPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNLAVCFGPVLLPARQTPSRTRLRGSGPGVSSAVDFKRHIEVLHYLLQSWPDTRRPSETPDVAPYLRPKRQPPLHLPLDGPEVVTRPRGRGGPESPPSNRYAGDWSVCGGDLLPRGRDFLSGPDYDHVTGSDSEEDEDESGEPRGTTDFEDEFDAPFNPHLNLKDFDALILDLERELSKQINVCL", "length": 735 }, "evidence": [ { "id": "A0A3Q2UAW2", "url": "https://omabrowser.org/oma/group/A0A3Q2UAW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SAN7-1", "protein_name": "Rho GTPase-activating protein SYDE1", "gene_name": "SYDE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEPLLRKTFSRLRGREKLPRKKSDAKERGRPAQRQEPSPPEPEPQALEGSQPGAEGPPSPEESRSPARGAYLQSLEPSSRRWVLGGAKPPEEAALGPGAPGSGEPAGEIWYNPIPEEDPRPPTAEPPGLQPGSAEPESLTSPGTAPASPPTKASRTKSPGPARRLSMKMKKLPELRRRLSLRSTRAGRERERAAPEGSVISRYHLDSSVGTPGRAAVAEGARGLRAGYLSDGDSPERPAGPPSPTAFRPYEVGPSARSPPAALWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDGVARARTGPLRGGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQGLLYAKLTLSEQHEAPSTAEPRVFGLPLPLLVEREQSPGQVPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSTAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMARGPPSRAPQSTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAHNRMTPQNLAVCFGPVLLPARQTPTRPRIRSSGPGLSNAVDFKRHIEVLHYLLQAWPDPRRPPEAPELVPYLRPKPQPPLHLPLAGPDVVTRPRDRSGPESPPSNRYAGDWSVCGRDFLPCGRDFLPGPDYDHVTGSDSEDEEEVGGETTGATDFEDDFEAPFNPHLNLKDFDALILDLERELSKQINVCL", "length": 735 }, "evidence": [ { "id": "A0A3Q2UAW2", "url": "https://omabrowser.org/oma/group/A0A3Q2UAW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZW31-1", "protein_name": "Rho GTPase-activating protein SYDE1", "gene_name": "SYDE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPLLRKTFSRLRGREKLPRKKSDAKERGHPAQRPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKPAEDTSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPGSAESEGLAPQGAAPASPPTKASRTKSPGPARRLSIKMKKLPELRRRLSLRGPRAGRERERAAPAGSVISRYHLDSSVGGPGPAAGPGGTRSPRAGYLSDGDSPERPAGPPSPTSFRPYEVGPAARAPPAALWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDGEARARTGPLRGGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQGLLYAKLTLSEQQEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDINVITGILKDYLRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHHIEVLHYLLQSWPDPRLPRQSPDVAPYLRPKRQPPLHLPLADPEVVTRPRGRGGPESPPSNRYAGDWSVCGRDFLPCGRDFLSGPDYDHVTGSDSEDEDEEVGEPRVTGDFEDDFDAPFNPHLNLKDFDALILDLERELSKQINVCL", "length": 735 }, "evidence": [ { "id": "A0A3Q2UAW2", "url": "https://omabrowser.org/oma/group/A0A3Q2UAW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBZ9-1", "protein_name": "Rho GTPase-activating protein SYDE1", "gene_name": "Syde1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPLLRKTFSRLRGREKLPRKKSEAKDRGHPAQRSEPKPPEPEPRVLEGSQAGAEVPPSPETPRSPTRGAYLQSLEPSSRRWVLGGAKPPEEISLGPRTPSSGEPAGEIWYNPIPEEDPRPPAPEPLGSQLASSEPEGPNIQGAAPTSPPTKTSRTKSPGPARRLSMKMKKLPELRRRLSLRSTRTGRDRERTAPAGSVISRYRLDSSVGTPGQASVAGGSRSPRGGYLSDGDSPERPGGPPSPTAFRPYEVGPSARTPPAALWGRLSLHLYGLGGLRPSPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTIFRGCQAQQLAVRLEPQGFLYAKLTLSEQQEAPATAEPRVFGLPLQLLVEREQSPGQVPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLRCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNXAVCFGPVLLPARQTPSRPRLRSSGPGVTSAVDFKRHIEVLHYLLQSWPDTRRPSDTPDGAVAPYLRPKRQPPLHLPLAGPEVVTRPRGRGGPESPPSNRYAGDWSVCGGDLLPCGRDFLSGPDYDHVTGSDSEEDDDETGEPRGTTDFEDEFDAPFNPHLNLKDFDALILDLERELSKQINVCL", "length": 737 }, "evidence": [ { "id": "A0A3Q2UAW2", "url": "https://omabrowser.org/oma/group/A0A3Q2UAW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" }, { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UAW2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 824, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UAW2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAW2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2UAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAW2" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 493, "end_pos": 705, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 411, "end_pos": 413 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 771, "end_pos": 773 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UAZ3-1", "uniprot_ac": "A0A3Q2UAZ3", "uniprot_id": "A0A3Q2UAZ3_CHICK", "mass": { "chemical_mass": 52925.0, "monoisotopic_mass": 52925.0 }, "refseq": {}, "gene_names": [ { "name": "RP1-27O5.3", "type": "recommended", "evidence": [ { "id": "A0A3Q2UAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain containing 8B", "type": "synonym", "evidence": [ { "id": "A0A3Q2UAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RP1-27O5.3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3", "locus": { "chromosome": "23", "start_pos": 5570521, "end_pos": 5563972, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017373", "url": "https://www.ensembl.org/id/ENSGALG00010017373" } ] } } ], "crossref": [ { "id": "A0A3Q2UAZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003408", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003408", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419659", "url": "https://www.ncbi.nlm.nih.gov/gene/419659", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419659", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419659", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKEANWP", "url": "https://omabrowser.org/oma/group/DKEANWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UAZ3", "url": "https://www.orthodb.org/?gene=A0A3Q2UAZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU00", "url": "https://www.orthodb.org/?gene=A0A8V0YU00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSP0", "url": "https://www.orthodb.org/?gene=F1NSP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSP0", "url": "https://www.uniprot.org/uniprotkb/F1NSP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSP0-1", "url": "https://www.uniprot.org/uniprotkb/F1NSP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMQSYYTKLLGELNEQRKRDFFCDCSIIVEGRIFKAHKNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSEAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMTDVVNFCKTYIRSSLDICRKIEREAAFYQADSGSGGSAREGPSHSTKGQGSTSALREKERMVGCQSDPPCGDCSSCHPLELVVRDLGGSDSPDDANSSLPKGVEPKVEFDADEVEVDVGGRLQQYPNALSLEQVDEGLHGGQAMDLACNNYHMKQFLEALLRNSSAQRKDDVVHHFVRGFEGRPEDAGVAMSSMMDIHSDWYGEDTGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNKPIICKGCRRTFTSSLSQGLRRFGLCDSCTCVTTTHEDSMPINLSLMEPSSEGQEKGDTDNDWPIYVESGEENDPAADDAEDKQEIHRSLADRETLT", "length": 475, "header": "tr|A0A3Q2UAZ3-1|A0A3Q2UAZ3_CHICK Isoform 1 of Zinc finger and BTB domain containing 8B OS=Gallus gallus OX=9031 GN=RP1-27O5.3 PE=4 SV=1 CANONICAL=A0A3Q2UAZ3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3/entry", "sequence": { "sequence": "MEMQSYYTKLLGELNEQRKRDFFCDCSIIVEGRIFKAHKNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSEAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMTDVVNFCKTYIRSSLDICRKIEREAAFYQADSGSGGSAREGPSHSTKGQGSTSALREKERMVGCQSDPPCGDCSSCHPLELVVRDLGGSDSPDDANSSLPKGVEPKVEFDADEVEVDVGGRLQQYPNALSLEQVDEGLHGGQAMDLACNNYHMKQFLEALLRNSSAQRKDDVVHHFVRGFEGRPEDAGVAMSSMMDIHSDWYGEDTGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNKPIICKGCRRTFTSSLSQGLRRFGLCDSCTCVTTTHEDSMPINLSLMEPSSEGQEKGDTDNDWPIYVESGEENDPAADDAEDKQEIHRSLADRETLT", "length": 475, "header": "tr|A0A3Q2UAZ3-1|A0A3Q2UAZ3_CHICK Isoform 1 of Zinc finger and BTB domain containing 8B OS=Gallus gallus OX=9031 GN=RP1-27O5.3 PE=4 SV=1 CANONICAL=A0A3Q2UAZ3-1" }, "locus": { "chromosome": "23", "start_pos": 5567796, "end_pos": 5564091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041918.1", "url": "https://www.ensembl.org/id/ENSGALT00010041918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024526.1", "url": "https://www.ensembl.org/id/ENSGALP00010024526.1" } ] } }, { "isoform_ac": "A0A8V0YU00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU00/entry", "sequence": { "sequence": "MEMQSYYTKLLGELNEQRKRDFFCDCSIIVEGRIFKAHKNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSEAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMTDVVNFCKTYIRSSLDICRKIEREAAFYQADSGSGGSAREGPSHSTKGQGSTSALREKERMVGCQSDPPCGDCSSCHPLELVVRDLGGSDSPDDANSSLPKGVEPKVEFDADEVEVDVGGRLQQYPNALSLEQVDEGLHGGQAMDLACNNYHMKQFLEALLRNSSAQRKDDVVHHFVRGFEGRPEDAGVAMSSMMDIHSDWYGEDTEADLFFICWSPEVLLLSQAWCPLGCSALTGMSPSSNVRDLEKKVVMSLSISAEMDSKDLGILSTYCNVGKQLTLSKLSYKEGRQLIHTPSDKTVQDMAHGIVLQAAERKSFMECSVLDSKLSHSCYFQFKYASMILKPIKTLYSPNAFR", "length": 462, "header": "tr|A0A8V0YU00-1|A0A3Q2UAZ3_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8B OS=Gallus gallus OX=9031 GN=RP1-27O5.3 PE=4 SV=1 CANONICAL=A0A3Q2UAZ3-1" }, "locus": { "chromosome": "23", "start_pos": 5566050, "end_pos": 5564091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041912.1", "url": "https://www.ensembl.org/id/ENSGALT00010041912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024520.1", "url": "https://www.ensembl.org/id/ENSGALP00010024520.1" } ] } }, { "isoform_ac": "F1NSP0-1", "url": "https://www.uniprot.org/uniprotkb/F1NSP0/entry", "sequence": { "sequence": "MEMQSYYTKLLGELNEQRKRDFFCDCSIIVEGRIFKAHKNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSEAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMTDVVNFCKTYIRSSLDICRKIEREAAFYQADSGSGGSAREGPSHSTKGQGSTSALREKERMVGCQSDPPCGDCSSCHPLELVVRDLGGSDSPDDANSSLPKGVEPKVEFDADEVEVDVGGRLQQYPNALSLEQVDEGLHGGQAMDLACNNYHMKQFLEALLRNSSAQRKDDVVHHFVRGFEGRPEDAGVAMSSMMDIHSDWYGEDTGERTRGSVVVIGEETISRVTSVTLSCSGIHC", "length": 344, "header": "tr|F1NSP0-1|A0A3Q2UAZ3_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8B OS=Gallus gallus OX=9031 GN=RP1-27O5.3 PE=4 SV=1 CANONICAL=A0A3Q2UAZ3-1" }, "locus": { "chromosome": "23", "start_pos": 5565122, "end_pos": 5564091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041907.1", "url": "https://www.ensembl.org/id/ENSGALT00010041907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024516.1", "url": "https://www.ensembl.org/id/ENSGALP00010024516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419659", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419659", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NAP8-1", "protein_name": "Zinc finger and BTB domain-containing protein 8B", "gene_name": "ZBTB8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDDKPQIQPNLSDRETLT", "length": 495 }, "evidence": [ { "id": "A0A3Q2UAZ3", "url": "https://omabrowser.org/oma/group/A0A3Q2UAZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UAZ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 475, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UAZ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UAZ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 421, "end_pos": 423 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UB88-1", "uniprot_ac": "A0A3Q2UB88", "uniprot_id": "A0A3Q2UB88_CHICK", "mass": { "chemical_mass": 69129.0, "monoisotopic_mass": 69129.0 }, "refseq": { "ac": "XP_040503315", "name": "interleukin-21 receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503315" }, "gene_names": [ { "name": "IL21R", "type": "recommended", "evidence": [ { "id": "A0A3Q2UB88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88" } ] }, { "name": "IL21R", "type": "synonym", "evidence": [ { "id": "XP_040503315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503315" } ] } ], "protein_names": [ { "name": "Interleukin 21 receptor", "type": "synonym", "evidence": [ { "id": "A0A3Q2UB88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88/entry#names_and_taxonomy" } ] }, { "name": "interleukin-21 receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040503315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503315" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503315" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UB88", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL21R", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88", "locus": { "chromosome": "14", "start_pos": 7332561, "end_pos": 7316727, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017285", "url": "https://www.ensembl.org/id/ENSGALG00010017285" } ] } } ], "crossref": [ { "id": "A0A3Q2UB88", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UB88", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006318", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006318", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416586", "url": "https://www.ncbi.nlm.nih.gov/gene/416586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416586", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGWAAPL", "url": "https://omabrowser.org/oma/group/CGWAAPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UB88", "url": "https://www.orthodb.org/?gene=A0A3Q2UB88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P495", "url": "https://www.orthodb.org/?gene=F1P495", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-9020958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040503315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB88", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB88-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P495", "url": "https://www.uniprot.org/uniprotkb/F1P495", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P495-1", "url": "https://www.uniprot.org/uniprotkb/F1P495-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQCEEASHLQGTVPMGQLGHPVRTKMRNKLWLQSISFFLLFQYSTCHENLTCFVDYVQTLSCLLRNDLGASPYNITATWVDEDDPENTVAACSLLELSRNANHTEYVCTVDMTELLADIRVQVDATEIADRQHVISIGFYMKDNIRPQPPFNLTAVFTEGYNISWETIHQNPLFYLLNGELEYQLRYKRRADTWETQKIKSVPEDKRTVVILPQEFQGNTEYEFQVRARPRGGTGYFGFWSEWSSRLTLKTSPAAVTQRAGMGWMLFFVVAMVITASITAFLAKQQSLWKKIACIPDPSAFFKPLYLMYNGDFKKWVGTSHMKMTIDLFEWEIVPSEVLEVFSMRPSNCTSQEEIRELKNDLPCKPCVSCLTTPVQDSLLSSVNSSSVTPDRSYGHLSIDTVTVADEFTPCNCQCNCNRMYKEQKHNGDEDSAEESGYPKVNIDDEDRRPSSALHLSDLSSQDKILASGSMSTDHLRTTGAPGHQKVEGALEGGMGSILEALCLHPNQWDLENPASLPSPDGESVSYSEGSCDFFPRGARPGGSYPMICLDLDTIDSGFVDSDCGSPVDFEFEQNSQTNAESVPLEQEGEDFPRSYVKQWISCHADSPASGTQTD", "length": 616, "header": "tr|A0A3Q2UB88-1|A0A3Q2UB88_CHICK Isoform 1 of Interleukin 21 receptor OS=Gallus gallus OX=9031 GN=IL21R PE=4 SV=1 CANONICAL=A0A3Q2UB88-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UB88-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB88/entry", "sequence": { "sequence": "MLQCEEASHLQGTVPMGQLGHPVRTKMRNKLWLQSISFFLLFQYSTCHENLTCFVDYVQTLSCLLRNDLGASPYNITATWVDEDDPENTVAACSLLELSRNANHTEYVCTVDMTELLADIRVQVDATEIADRQHVISIGFYMKDNIRPQPPFNLTAVFTEGYNISWETIHQNPLFYLLNGELEYQLRYKRRADTWETQKIKSVPEDKRTVVILPQEFQGNTEYEFQVRARPRGGTGYFGFWSEWSSRLTLKTSPAAVTQRAGMGWMLFFVVAMVITASITAFLAKQQSLWKKIACIPDPSAFFKPLYLMYNGDFKKWVGTSHMKMTIDLFEWEIVPSEVLEVFSMRPSNCTSQEEIRELKNDLPCKPCVSCLTTPVQDSLLSSVNSSSVTPDRSYGHLSIDTVTVADEFTPCNCQCNCNRMYKEQKHNGDEDSAEESGYPKVNIDDEDRRPSSALHLSDLSSQDKILASGSMSTDHLRTTGAPGHQKVEGALEGGMGSILEALCLHPNQWDLENPASLPSPDGESVSYSEGSCDFFPRGARPGGSYPMICLDLDTIDSGFVDSDCGSPVDFEFEQNSQTNAESVPLEQEGEDFPRSYVKQWISCHADSPASGTQTD", "length": 616, "header": "tr|A0A3Q2UB88-1|A0A3Q2UB88_CHICK Isoform 1 of Interleukin 21 receptor OS=Gallus gallus OX=9031 GN=IL21R PE=4 SV=1 CANONICAL=A0A3Q2UB88-1" }, "locus": { "chromosome": "14", "start_pos": 7332077, "end_pos": 7321447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041663.1", "url": "https://www.ensembl.org/id/ENSGALT00010041663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024370.1", "url": "https://www.ensembl.org/id/ENSGALP00010024370.1" } ] } }, { "isoform_ac": "F1P495-1", "url": "https://www.uniprot.org/uniprotkb/F1P495/entry", "sequence": { "sequence": "MRNKLWLQSISFFLLFQYSTCHENLTCFVDYVQTLSCLLRNDLGASPYNITATWVDEDDPENTVAACSLLELSRNANHTEYVCTVDMTELLADIRVQVDATEIADRQHVISIGFYMKDNIRPQPPFNLTAVFTEGYNISWETIHQNPLFYLLNGELEYQLRYKRRADTWETQKIKSVPEDKRTVVILPQEFQGNTEYEFQVRARPRGGTGYFGFWSEWSSRLTLKTSPAAVTQRAGMGWMLFFVVAMVITASITAFLAKQQSLWKKIACIPDPSAFFKPLYLMYNGDFKKWVGTSHMKMTIDLFEWEIVPSEVLEVFSMRPSNCTSQEEIRELKNDLPCKPCVSCLTTPVQDSLLSSVNSSSVTPDRSYGHLSIDTVTVADEFTPCNCQCNCNRMYKEQKHNGDEDSAEESGYPKVNIDDEDRRPSSALHLSDLSSQDKILASGSMSTDHLRTTGAPGHQKVEGALEGGMGSILEALCLHPNQWDLENPASLPSPDGESVSYSEGSCDFFPRGARPGGSYPMICLDLDTIDSGFVDSDCGSPVDFEFEQNSQTNAESVPLEQEGEDFPRSYVKQWISCHADSPASGTQTD", "length": 590, "header": "tr|F1P495-1|A0A3Q2UB88_CHICK Computationally mapped isoform of Interleukin 21 receptor OS=Gallus gallus OX=9031 GN=IL21R PE=4 SV=1 CANONICAL=A0A3Q2UB88-1" }, "locus": { "chromosome": "14", "start_pos": 7332077, "end_pos": 7322900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041671.1", "url": "https://www.ensembl.org/id/ENSGALT00010041671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024375.1", "url": "https://www.ensembl.org/id/ENSGALP00010024375.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416586", "resource": "KEGG Pathway" }, { "id": "R-GGA-9020958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020958", "resource": "Reactome", "description": "Interleukin-21 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AE50-1", "protein_name": "Interleukin 21 receptor", "gene_name": "IL21R", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLCGWAAPLLLLLLQGAWGCSDLVCYTDYLHTVTCVLETWTLHPSALTLTWQDLYGEMEEEVTSCSLRLSTRNATHAEYTCHMDVFQFMADDIFSINMTDQSGNHSQECGSFVLANSIKPSPPFNVTVTFSGHYNISWSSDYNVFALKGKLQYELRYRKLGDPWAQSPGRKLISVDSRSVSLLPLEFHKGSSYELQLRAGPQPDSSFQGTWSEWSDPVIFHTQPEEMKRNWYPHLLLILILVCPVLVFLGLKIHLPWRLWKKVWVQVPSPEPFFQPLYVGHSGDFKRWVGTPFPPSSLELRSWSVGVPSILEMHSQCPAQRAAKGLAPMELPEPADLVEADGVPEPGSWDPAPSTASTLGGSAYSQERDRPYGKLSIETVTVRDAEGPCAWPCTCGDDDSYPALNLEPGSGTEDPLLDPEATFLSCGCVSARGSVGLGGPAGSVLARVKPSPEDEAGWAPGPPWGDGPPRGVSDSEAGSPPAGLDMDTFDSGFADSDCGSPVECDFSSPRDEGPPRSYLRQWVVMSPPLAESGPQAS", "length": 537 }, "evidence": [ { "id": "A0A3Q2UB88", "url": "https://omabrowser.org/oma/group/A0A3Q2UB88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BBE5-1", "protein_name": "Interleukin 21 receptor", "gene_name": "IL21R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040524233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524233" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UBE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121110414", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBE2", "locus": {} } ], "crossref": [ { "id": "A0A3Q2UBE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UBE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054781", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": 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] } ], "sequence": { "sequence": "MMGPSKPPLSDAPLRPTTQLYRSEAKSLQTQLQFNRNVPAVPENLSLRFSNPHPIIIEKLKLSNDQRNLAESDDPSVRSSGMFSVISEERLKLAIHLAKRDIKRRQLEEQAKQQVFGDAVNKSLLAQKSQEQKNKVSESLEKKSGLEFQTRLKCHQKLVQPPKMKTTTSDTKVYLYTPNEGMLIPAVLGSSLTHNTRPDPKTNVKIKENKNIFEIQRLQKELRSCVQKIEDLTKKERDEENLDADEEQQVCTQRQKQAARSAQMLYVLQQQVKEIQGDLEKLSPHKIKHTKKSRAVSRLAAAHRGVIRALQAFANQFTHQTAQWIPTHYKELGSLIRQLSLCSAKLELDSSTSDVIIDILMQVEDLISLLEKKQTPKKVKKCLSTSHCKSPVNTVTFPARKQLTIPKGENKPLIVKERHGQEPRKSSAARGLLIDKHQHVAKNSAVQKMNNHAHILHDKFQEANDLPTPESNTVLQGSLDALVRSRAVKKDPILQTGSLKKKDILLPAKSQGMPKSLKPRQVQPPGKHARFQETTIAFQLKENKRFVKESSIPWMPPSPTSLPASPKRLAWREAEASRRMKVLTDLSRGEMKKVQELRLQGASPTQYADKVDKAVCEHLEHPLNRAQQINISLESNGHLKDSSIISQLSTHAAEKAAANADILSEKVLDDLLEDTAQEFWNMEQHKRLQAESLFVADSLSLETMLQRMEEIERYQETVCRRFTQIVYSDSEFRAQEDKIDQQMALIAQIPTSPHSIQITKLTRQIEPETDILFEKLFDDNGTDENKEAQEKLLTGNYILQPLTQNSVQKESYVSLSVTMHMLQSILDYNSKYKHHLKLIFHEAVGSFNPWQIAESLADELTDESLFDVAAELQDVCEDYAEAVFTSEFLQPAQSDTPATGEGVLFITCVLANCQTNSLLQYIS", "length": 923, "header": "tr|A0A3Q2UE38-1|A0A3Q2UE38_CHICK Isoform 1 of KIAA0753 OS=Gallus gallus OX=9031 GN=KIAA0753 PE=4 SV=1 CANONICAL=A0A3Q2UE38-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UE38-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38/entry", "sequence": { "sequence": "MMGPSKPPLSDAPLRPTTQLYRSEAKSLQTQLQFNRNVPAVPENLSLRFSNPHPIIIEKLKLSNDQRNLAESDDPSVRSSGMFSVISEERLKLAIHLAKRDIKRRQLEEQAKQQVFGDAVNKSLLAQKSQEQKNKVSESLEKKSGLEFQTRLKCHQKLVQPPKMKTTTSDTKVYLYTPNEGMLIPAVLGSSLTHNTRPDPKTNVKIKENKNIFEIQRLQKELRSCVQKIEDLTKKERDEENLDADEEQQVCTQRQKQAARSAQMLYVLQQQVKEIQGDLEKLSPHKIKHTKKSRAVSRLAAAHRGVIRALQAFANQFTHQTAQWIPTHYKELGSLIRQLSLCSAKLELDSSTSDVIIDILMQVEDLISLLEKKQTPKKVKKCLSTSHCKSPVNTVTFPARKQLTIPKGENKPLIVKERHGQEPRKSSAARGLLIDKHQHVAKNSAVQKMNNHAHILHDKFQEANDLPTPESNTVLQGSLDALVRSRAVKKDPILQTGSLKKKDILLPAKSQGMPKSLKPRQVQPPGKHARFQETTIAFQLKENKRFVKESSIPWMPPSPTSLPASPKRLAWREAEASRRMKVLTDLSRGEMKKVQELRLQGASPTQYADKVDKAVCEHLEHPLNRAQQINISLESNGHLKDSSIISQLSTHAAEKAAANADILSEKVLDDLLEDTAQEFWNMEQHKRLQAESLFVADSLSLETMLQRMEEIERYQETVCRRFTQIVYSDSEFRAQEDKIDQQMALIAQIPTSPHSIQITKLTRQIEPETDILFEKLFDDNGTDENKEAQEKLLTGNYILQPLTQNSVQKESYVSLSVTMHMLQSILDYNSKYKHHLKLIFHEAVGSFNPWQIAESLADELTDESLFDVAAELQDVCEDYAEAVFTSEFLQPAQSDTPATGEGVLFITCVLANCQTNSLLQYIS", "length": 923, "header": "tr|A0A3Q2UE38-1|A0A3Q2UE38_CHICK Isoform 1 of KIAA0753 OS=Gallus gallus OX=9031 GN=KIAA0753 PE=4 SV=1 CANONICAL=A0A3Q2UE38-1" }, "locus": { "chromosome": "19", "start_pos": 10311555, "end_pos": 10290867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070812.1", "url": "https://www.ensembl.org/id/ENSGALT00010070812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043503.1", "url": "https://www.ensembl.org/id/ENSGALP00010043503.1" } ] } }, { "isoform_ac": "A0A8V1AJA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA0/entry", "sequence": { "sequence": "MMGPSKPPLSDAPLRPTTQLYRSEAKSLQTQLQFNRNVPAVPENLSLRFSNPHPIIIEKLKLSNDQRNLAESDDPSVRSSGMFSVISEERLKLAIHLAKRDIKRRQLEEQAKQQVFGDAVNKSLLAQKSQEQKNKVSESLEKKSGLEFQTRLKCHQKLVQPPKMKTTTSDTKVYLYTPNEGMLIPAVLGSSLTHNTRPDPKTNVKIKENKNIFEIQRLQKELRSCVQKIEDLTKKERDEENLDADEEQQVCTQRQKQAARSAQMLYVLQQQVKEIQGDLEKLSPHKIKHTKKSRAVSRLAAAHRGVIRALQAFANQFTHQTAQWIPTHYKELGSLIRQLSLCSAKLELDSSTSDVIIDILMQVEDLISLLEKKQTPKKVKKCLSTSHCKSPVNTVTFPARKQLTIPKGENKPLIVKERHGQEPRKSSAARGLLIDKHQHVAKNSAVQKMNNHAHILHDKFQEANDLPTPESNTVLQGSLDALVRSRAVKKDPILQTGSLKKKDILLPAKSQGMPKSLKPRQVQPPGKHARFQETTIAFQLKENKRFVKESSIPWMPPSPTSLPASPKRLAWREAEASRRMKVLTDLSRGEMKKVQELRLQGASPTQYADKVDKAVCEHLEHPLNRAQQINISLESNGHLKDSSIISQLSTHAAEKAAANADILSEKVLDDLLEDTAQEFWNMEQHKRLQAESLFVADSLSLETMLQRMEEIERYQETVCRRFTQIVYSDSEFRAQEDKIDQQMALIAQIPTSPHSIQITKLTRQIEPETDILFEKLFDDNGTDENKEAQEKLLTGNYILQPLTQNSVQKESYVSLSVTMHMLQSILDYNSKYKHHLKLIFHEAVGSFNPWQIAESLADELTDESLFDVAAELQDVCEDYAEAVFTSEFLQPAQ", "length": 893, "header": "tr|A0A8V1AJA0-1|A0A3Q2UE38_CHICK Computationally mapped isoform of KIAA0753 OS=Gallus gallus OX=9031 GN=KIAA0753 PE=4 SV=1 CANONICAL=A0A3Q2UE38-1" }, "locus": { "chromosome": "19", "start_pos": 10308405, "end_pos": 10290867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070811.1", "url": "https://www.ensembl.org/id/ENSGALT00010070811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043502.1", "url": "https://www.ensembl.org/id/ENSGALP00010043502.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE38", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE38", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE38", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE38", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38" } ], "pmid": "" }, { "name": "cytosolic ciliogenesis", "id": "GO:0061824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061824", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UE38", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UE38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 923, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UE38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UE38" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UES0-1", "uniprot_ac": "A0A3Q2UES0", "uniprot_id": "A0A3Q2UES0_CHICK", "mass": { "chemical_mass": 9897.0, "monoisotopic_mass": 9897.0 }, "refseq": { "ac": "XP_040552025", "name": "feather keratin 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552025" }, "gene_names": [ { "name": "LOC107052805", "type": "recommended", "evidence": [ { "id": "A0A3Q2UES0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0" } ] }, { "name": "LOC107052805", "type": "synonym", "evidence": [ { "id": "XP_040552025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552025" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A3Q2UES0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0/entry#names_and_taxonomy" } ] }, { "name": "feather keratin 1-like", "type": "synonym", "evidence": [ { "id": "XP_040552025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552025" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040552025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552025" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UES0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107052805", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000047317", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000047317", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107052805", "url": "https://www.ncbi.nlm.nih.gov/gene/107052805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425781", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425781", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UES0", "url": "https://www.orthodb.org/?gene=A0A3Q2UES0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040552025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UES0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSNLCRPCGPAPLANSCNEPCVRQCQDSQVVIQPSTVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A3Q2UES0-1|A0A3Q2UES0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC107052805 PE=3 SV=1 CANONICAL=A0A3Q2UES0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UES0/entry", "sequence": { "sequence": "MSCSNLCRPCGPAPLANSCNEPCVRQCQDSQVVIQPSTVVVTLPGPILSSFPQNTAVGSSSSAAVGSELSAQGVAISSGGFGFGGLGCFNGWRARYPC", "length": 98, "header": "tr|A0A3Q2UES0-1|A0A3Q2UES0_CHICK Isoform 1 of Keratin OS=Gallus gallus 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31785:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31785:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UF71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAAAAKSEKLDEAQALARSCAGRPDFQPCDGLSLCATHSHGRCFRLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPVRPRESTNTIQISVSLTEHFLKFAPVFQPPLPPDSPQFCTIADLFIDNYRVKCINGKMCYVQRQPPPVPHKTKPEEVSVRNALITKESNTPKTDHCSSPSSSEDSGINAVGVHYMESCDEDTEGVAELSSEEDYSPDSSWEPDECPLLSPSQCEMEVIETIETTV", "length": 243, "header": "tr|A0A3Q2UF71-1|A0A3Q2UF71_CHICK Isoform 1 of Chromosome 3 open reading frame 70 OS=Gallus gallus OX=9031 GN=C3orf70 PE=3 SV=1 CANONICAL=A0A3Q2UF71-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF71/entry", "sequence": { "sequence": "MSGAAAAKSEKLDEAQALARSCAGRPDFQPCDGLSLCATHSHGRCFRLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPVRPRESTNTIQISVSLTEHFLKFAPVFQPPLPPDSPQFCTIADLFIDNYRVKCINGKMCYVQRQPPPVPHKTKPEEVSVRNALITKESNTPKTDHCSSPSSSEDSGINAVGVHYMESCDEDTEGVAELSSEEDYSPDSSWEPDECPLLSPSQCEMEVIETIETTV", "length": 243, "header": "tr|A0A3Q2UF71-1|A0A3Q2UF71_CHICK Isoform 1 of Chromosome 3 open reading frame 70 OS=Gallus gallus OX=9031 GN=C3orf70 PE=3 SV=1 CANONICAL=A0A3Q2UF71-1" }, "locus": { "chromosome": "9", "start_pos": 3208945, "end_pos": 3191554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059803.1", "url": "https://www.ensembl.org/id/ENSGALT00010059803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036563.1", "url": "https://www.ensembl.org/id/ENSGALP00010036563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424878", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UIT0-1", "protein_name": "Chromosome 13 C3orf70 homolog", "gene_name": "C3orf70", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAAAPVSERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPAKPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHKMSPEEVSAHDALISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIETTV", "length": 250 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A3M1-1", "protein_name": "Similar to human chromosome 3 open reading frame 70", "gene_name": "C11h3orf70", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAATAPERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVGQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPHSQKMSPEEVSAHDALISKESDTPKLGHCSSPSGSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETMETTV", "length": 246 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KNX6-1", "protein_name": "UPF0524 protein C3orf70 homolog B", "gene_name": "c3orf70b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYSGAQKALKSDKLDEAQALAKSCAGRPDFLPCDGLSICATHSHGKCFKLHWCCYLGWCHCKYVYQPMTNVAQLPSTPVPAAPSDCPDTIDLSISLTERFLRISPCFQAPPCPESPKYCNIAELFIDDYIVKRINGKMCYVQRPQAHVEPAQMNPIQKQHTEDKQIVEETVKGPKMGHCSSPSTSEDSGINALGGHFLESCEEESEEEDELSTDGHSSPGSLWDQDECTLLSPSKSMVEIIENIETTV", "length": 249 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NLC5-1", "protein_name": "UPF0524 protein C3orf70", "gene_name": "C3orf70", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAAASPASERGWKSEKLDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYMYQPMTPVEQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHRMSPEEVSAHDALISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIETTV", "length": 250 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7E369-1", "protein_name": "UPF0524 protein C3orf70 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAAAAPAPERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPAKPREPANTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHKMSPEEVSAHDAFISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIETTV", "length": 250 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6GQU0-1", "protein_name": "UPF0524 protein C3orf70 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAATAPERGWKSEKVDEAQALARSCAARRPDFQPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTPVEQLPSTEIPAKPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQQAPHSQKMSPEEVSAHDALISKESDTPKLGHCSSPSGSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETMETTV", "length": 248 }, "evidence": [ { "id": "A0A3Q2UF71", "url": "https://omabrowser.org/oma/group/A0A3Q2UF71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UF71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UF71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UF71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UF71" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UFR1-1", "uniprot_ac": "A0A3Q2UFR1", "uniprot_id": "A0A3Q2UFR1_CHICK", "mass": { "chemical_mass": 6242.0, "monoisotopic_mass": 6242.0 }, "refseq": { "ac": "NP_001338410", "name": "epidermal differentiation protein containing glutamine (Q) repeats-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338410" }, "gene_names": [ { "name": "LOC107055098", "type": "recommended", "evidence": [ { "id": "A0A3Q2UFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1" } ] }, { "name": "LOC107055098", "type": "synonym", "evidence": [ { "id": "NP_001338410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338410" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A3Q2UFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein containing glutamine (Q) repeats-like", "type": "synonym", "evidence": [ { "id": "NP_001338410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338410" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888551.2025.1, SRR12888552.126409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000349.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001338410", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338410" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055098", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1", "locus": {} } ], "crossref": [ { "id": "A0A3Q2UFR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UFR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055098", "url": "https://www.ncbi.nlm.nih.gov/gene/107055098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:107055098", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055098", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001338410", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSHQQKQQQQIPAQCQQKCPPKGVEQCQAPKGQTKCPVKSIPQQQQQQQCPKQK", "length": 55, "header": "tr|A0A3Q2UFR1-1|A0A3Q2UFR1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC107055098 PE=4 SV=1 CANONICAL=A0A3Q2UFR1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UFR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFR1/entry", "sequence": { "sequence": "MSSHQQKQQQQIPAQCQQKCPPKGVEQCQAPKGQTKCPVKSIPQQQQQQQCPKQK", "length": 55, "header": "tr|A0A3Q2UFR1-1|A0A3Q2UFR1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC107055098 PE=4 SV=1 CANONICAL=A0A3Q2UFR1-1" }, "locus": { "chromosome": "25", "start_pos": 1320906, "end_pos": 1320742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067265.1", "url": "https://www.ensembl.org/id/ENSGALT00010067265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041169.1", "url": "https://www.ensembl.org/id/ENSGALP00010041169.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107055098", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055098", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UFR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 55, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UFR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UFR1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UFT5-1", "uniprot_ac": "A0A3Q2UFT5", "uniprot_id": "A0A3Q2UFT5_CHICK", "mass": { "chemical_mass": 21826.0, "monoisotopic_mass": 21826.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM252", "type": "recommended", "evidence": [ { "id": "A0A3Q2UFT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5" } ] } ], "protein_names": [ { "name": "Transmembrane protein 252", "type": "synonym", "evidence": [ { "id": "A0A3Q2UFT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM252", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5", "locus": { "chromosome": "Z", "start_pos": 26068829, "end_pos": 26065126, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011444", "url": "https://www.ensembl.org/id/ENSGALG00010011444" } ] } } ], "crossref": [ { "id": "A0A3Q2UFT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UFT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000049973", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049973", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR031363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UFT5", "url": "https://www.orthodb.org/?gene=A0A3Q2UFT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35682:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35682:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2UFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UFT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSTAETDSKQTAGGSFVLCLLGNMKKVFFSLIRLSVLLLSFSIICLGVLCIYTGSPACGCGNKKLVAYCLLTLGLLLLVAGVFWSTVHEAMKYGGLSSIFMRNPDLTELRVSTIDRPDFYPPSYEDSTDPGKQTFPLPVGSAPKEQEVINMPPPLYSESSTESITEMNEPEQPPPYELPGQVLSPVRESDACALTQDSVC", "length": 201, "header": "tr|A0A3Q2UFT5-1|A0A3Q2UFT5_CHICK Isoform 1 of Transmembrane protein 252 OS=Gallus gallus OX=9031 GN=TMEM252 PE=4 SV=1 CANONICAL=A0A3Q2UFT5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UFT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UFT5/entry", "sequence": { "sequence": "MRSTAETDSKQTAGGSFVLCLLGNMKKVFFSLIRLSVLLLSFSIICLGVLCIYTGSPACGCGNKKLVAYCLLTLGLLLLVAGVFWSTVHEAMKYGGLSSIFMRNPDLTELRVSTIDRPDFYPPSYEDSTDPGKQTFPLPVGSAPKEQEVINMPPPLYSESSTESITEMNEPEQPPPYELPGQVLSPVRESDACALTQDSVC", "length": 201, "header": "tr|A0A3Q2UFT5-1|A0A3Q2UFT5_CHICK Isoform 1 of Transmembrane protein 252 OS=Gallus gallus OX=9031 GN=TMEM252 PE=4 SV=1 CANONICAL=A0A3Q2UFT5-1" }, "locus": { "chromosome": "Z", "start_pos": 26066891, "end_pos": 26065304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027385.1", "url": "https://www.ensembl.org/id/ENSGALT00010027385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015639.1", "url": "https://www.ensembl.org/id/ENSGALP00010015639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UFT5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 201, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UFT5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UFT5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UGE4-1", "uniprot_ac": "A0A3Q2UGE4", "uniprot_id": "A0A3Q2UGE4_CHICK", "mass": { "chemical_mass": 15188.0, "monoisotopic_mass": 15188.0 }, "refseq": { "ac": "NP_001264795", "name": "large ribosomal subunit protein mL41", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264795" }, "gene_names": [ { "name": "MRPL41", "type": "recommended", "evidence": [ { "id": "A0A3Q2UGE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4" } ] }, { "name": "MRPL41", "type": "synonym", "evidence": [ { "id": "NP_001264795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264795" } ] } ], "protein_names": [ { "name": "Mitochondrial ribosomal protein L41", "type": "synonym", "evidence": [ { "id": "A0A3Q2UGE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein mL41", "type": "synonym", "evidence": [ { "id": "NP_001264795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264795" } ] } ], "function": [ { "annotation": "##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU270193.1, CN210617.1 and BU329295.1. On Apr 25, 2013 this sequence version replaced XP_415536.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264795", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264795" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4", "locus": { "chromosome": "17", "start_pos": 2248140, "end_pos": 2259166, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028921", "url": "https://www.ensembl.org/id/ENSGALG00010028921" } ] } } ], "crossref": [ { "id": "A0A3Q2UGE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UGE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000051567", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000051567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417261", "url": "https://www.ncbi.nlm.nih.gov/gene/417261", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417261", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417261", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRMSAWT", "url": "https://omabrowser.org/oma/group/DRMSAWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UGE4", "url": "https://www.orthodb.org/?gene=A0A3Q2UGE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21338:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21338:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264795", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLTELARGLVRGADRMSPFTSKRGPRSYNKGRGAKKMGVLTSSKKFILIKEMVPQFVVPDLAGFKLKPYVSYRAPEGSEPPMTAKQLFTELVAPRIEKDVKEGTFDPNALEKYGFEPTQEGKLFQLFPKNYVR", "length": 135, "header": "tr|A0A3Q2UGE4-1|A0A3Q2UGE4_CHICK Isoform 1 of Mitochondrial ribosomal protein L41 OS=Gallus gallus OX=9031 GN=MRPL41 PE=1 SV=1 CANONICAL=A0A3Q2UGE4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UGE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4/entry", "sequence": { "sequence": "MGLLTELARGLVRGADRMSPFTSKRGPRSYNKGRGAKKMGVLTSSKKFILIKEMVPQFVVPDLAGFKLKPYVSYRAPEGSEPPMTAKQLFTELVAPRIEKDVKEGTFDPNALEKYGFEPTQEGKLFQLFPKNYVR", "length": 135, "header": "tr|A0A3Q2UGE4-1|A0A3Q2UGE4_CHICK Isoform 1 of Mitochondrial ribosomal protein L41 OS=Gallus gallus OX=9031 GN=MRPL41 PE=1 SV=1 CANONICAL=A0A3Q2UGE4-1" }, "locus": { "chromosome": "17", "start_pos": 2258954, "end_pos": 2258550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069973.1", "url": "https://www.ensembl.org/id/ENSGALT00010069973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043099.1", "url": "https://www.ensembl.org/id/ENSGALP00010043099.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417261", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1F1K9-1", "protein_name": "Mitochondrial ribosomal protein L41", "gene_name": "MRPL41", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLLSGAARALVRGADRMSKWTSKRGPRTFCKGRGAKGTGFHGRDGKFVQIKEMIPELVVPELAGFKLKPYVNYRAPEGTDTPLTAKQLFLETAAPAIEKDFKAGTFDPEHLEKYGFEPTQEGKLFQLYPKNFPR", "length": 135 }, "evidence": [ { "id": "A0A3Q2UGE4", "url": "https://omabrowser.org/oma/group/A0A3Q2UGE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I5Y6-1", "protein_name": "39S ribosomal protein L41, mitochondrial", "gene_name": "Mrpl41", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLTAVTQGLVRGADRMSKWTSKRGPRTFVKSRGAKRTGIYTSNGKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAPAGIDTPLTAKELFLQTAAPAIEKDFIEGTFDADNLEKYGFEPTQEGKLFQLYPKNFPR", "length": 135 }, "evidence": [ { "id": "A0A3Q2UGE4", "url": "https://omabrowser.org/oma/group/A0A3Q2UGE4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BJX1-1", "protein_name": "Large ribosomal subunit protein mL41", "gene_name": "Mrpl41", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFLTAVTQGLVRGADRMSKWTSKRGPRTFTKSRGAKKTGFYTNRKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAPAGIDTPLTAKALFLETVAPAIEKDFKEGTFDANNLEKYGFEPTQEGKLFQLYPKNFPR", "length": 134 }, "evidence": [ { "id": "A0A3Q2UGE4", "url": "https://omabrowser.org/oma/group/A0A3Q2UGE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXM3-1", "protein_name": "Large ribosomal subunit protein mL41", "gene_name": "MRPL41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVLAAAARCLVRGADRMSKWTSKRGPRSFRGRKGRGAKGIGFLTSGWRFVQIKEMVPEFVVPDLTGFKLKPYVSYLAPESEETPLTAAQLFSEAVAPAIEKDFKDGTFDPDNLEKYGFEPTQEGKLFQLYPRNFLR", "length": 137 }, "evidence": [ { "id": "A0A3Q2UGE4", "url": "https://omabrowser.org/oma/group/A0A3Q2UGE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQN7-1", "protein_name": "Large ribosomal subunit protein mL41", "gene_name": "Mrpl41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFLTAVTQGLVRGADRMSKWTSKRGPRTFTKSRGAKKTGIYTSDRKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAPAGIDTPLTAKALFQETVAPAIEKDFKEGTFDANNLEKYGFEPTQEGKLFQLYPKNFPR", "length": 135 }, "evidence": [ { "id": "A0A3Q2UGE4", "url": "https://omabrowser.org/oma/group/A0A3Q2UGE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UGE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UGE4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 135, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UGE4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UGE4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UH26-1", "uniprot_ac": "A0A3Q2UH26", "uniprot_id": "A0A3Q2UH26_CHICK", "mass": { "chemical_mass": 12391.0, "monoisotopic_mass": 12391.0 }, "refseq": { "ac": "NP_001264902", "name": "scale keratin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264902" }, "gene_names": [ { "name": "LOC100859616", "type": "recommended", "evidence": [ { "id": "A0A3Q2UH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26" } ] }, { "name": "LOC100859616", "type": "synonym", "evidence": [ { "id": "NP_001264902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264902" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A3Q2UH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26/entry#names_and_taxonomy" } ] }, { "name": "scale keratin-like", "type": "synonym", "evidence": [ { "id": "NP_001264902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264902" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX277226.4, BX277225.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000349.1. On Dec 1, 2021 this sequence version replaced NP_001264902.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UH26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859616", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26", "locus": {} } ], "crossref": [ { "id": "A0A3Q2UH26", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UH26", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859616", "url": "https://www.ncbi.nlm.nih.gov/gene/100859616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859616", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859616", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "gga:426912", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRECRLC", "url": "https://omabrowser.org/oma/group/IRECRLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UH26", "url": "https://www.orthodb.org/?gene=A0A3Q2UH26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264902", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UH26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UH26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRRYASPACSPCPLPRYSRKFWNTCGPC", "length": 121, "header": "tr|A0A3Q2UH26-1|A0A3Q2UH26_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859616 PE=3 SV=1 CANONICAL=A0A3Q2UH26-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UH26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26/entry", "sequence": { "sequence": "MSCYDLCPPKTSVAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRRYASPACSPCPLPRYSRKFWNTCGPC", "length": 121, "header": "tr|A0A3Q2UH26-1|A0A3Q2UH26_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC100859616 PE=3 SV=1 CANONICAL=A0A3Q2UH26-1" }, "locus": { "chromosome": "25", "start_pos": 1450975, "end_pos": 1450613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069084.1", "url": "https://www.ensembl.org/id/ENSGALT00010069084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042526.1", "url": "https://www.ensembl.org/id/ENSGALP00010042526.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859616", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859616", "resource": "KEGG Pathway" }, { "id": "gga:426912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426912", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UH26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UH26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q2UH26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 121, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q2UH26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q2UH26" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q2UH76-1", "uniprot_ac": "A0A3Q2UH76", "uniprot_id": "A0A3Q2UH76_CHICK", "mass": { "chemical_mass": 36746.0, "monoisotopic_mass": 36746.0 }, "refseq": { "ac": "XP_423953", "name": "coiled-coil domain-containing protein 166", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423953" }, "gene_names": [ { "name": "CCDC166", "type": "recommended", "evidence": [ { "id": "A0A3Q2UH76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76" } ] }, { "name": "CCDC166", "type": "synonym", "evidence": [ { "id": "XP_423953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423953" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 166", "type": "synonym", "evidence": [ { "id": "A0A3Q2UH76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 166", "type": "synonym", "evidence": [ { "id": "XP_423953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_423953.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423953" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UH76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC166", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000053276", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000053276", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426291", "url": "https://www.ncbi.nlm.nih.gov/gene/426291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426291", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHTRRQL", "url": "https://omabrowser.org/oma/group/HHTRRQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UH76", "url": "https://www.orthodb.org/?gene=A0A3Q2UH76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UH76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UH76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKARQRKQDGVGAGKNKEVRTGNKEELKRIKSGDTSMEMPVRERNSYLQKEYEILTGHMNTYMGRVERFLQENKFLEEEAKRNRKESNIYLSYLAKHSQRCQNLIITLNEQNEANLSQVQKEKEQLISQYTEKEKEVRNCLVEVEAKYSLMNSEVEDLQPFKDLQVEQTKKIKELEKELLVTKIHHSEEMHKIKSRFLQAKADREEDSRQQILALTKRAEEAAIQSLIQHIKQVKAENRHLRQELLRLIQCSKVLKEMQVELREQQQQLLREKHCTQDMAHARHRLHQQEARRANQGACSSHGPFKRGY", "length": 311, "header": "tr|A0A3Q2UH76-1|A0A3Q2UH76_CHICK Isoform 1 of Coiled-coil domain containing 166 OS=Gallus gallus OX=9031 GN=CCDC166 PE=4 SV=1 CANONICAL=A0A3Q2UH76-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UH76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76/entry", "sequence": { "sequence": "MASKARQRKQDGVGAGKNKEVRTGNKEELKRIKSGDTSMEMPVRERNSYLQKEYEILTGHMNTYMGRVERFLQENKFLEEEAKRNRKESNIYLSYLAKHSQRCQNLIITLNEQNEANLSQVQKEKEQLISQYTEKEKEVRNCLVEVEAKYSLMNSEVEDLQPFKDLQVEQTKKIKELEKELLVTKIHHSEEMHKIKSRFLQAKADREEDSRQQILALTKRAEEAAIQSLIQHIKQVKAENRHLRQELLRLIQCSKVLKEMQVELREQQQQLLREKHCTQDMAHARHRLHQQEARRANQGACSSHGPFKRGY", "length": 311, "header": "tr|A0A3Q2UH76-1|A0A3Q2UH76_CHICK Isoform 1 of Coiled-coil domain containing 166 OS=Gallus gallus OX=9031 GN=CCDC166 PE=4 SV=1 CANONICAL=A0A3Q2UH76-1" }, "locus": { "chromosome": "2", "start_pos": 148854657, "end_pos": 148853725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019776.1", "url": "https://www.ensembl.org/id/ENSGALT00010019776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011324.1", "url": "https://www.ensembl.org/id/ENSGALP00010011324.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426291", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3MXG2-1", "protein_name": "Coiled-coil domain containing 166", "gene_name": "CCDC166", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKKKRGPGAGRRGGAAGEGTEPPLSERAQYLQREHKLLSEELEACKQRVDQVLQENDFLDSEAPRLREENRLYASYASTRAQRCANAIVRLEEQNRVSLSQIHWQRAELASIYRGREDGVRAQLLEMEARAAQMAQQVQELQPYKELQLEQLARIRALERELLHMRVEHTQLLHRVKRRFLEDKAAFEREARQRVQSLARRAEREAARALLAHTQAIRVDNGRLRQELLRLLRRAQVLQDTRRQLLEQREQLRREHEDTRDLARVHGWLRRGPEGPPLWEPSPAASDPESFPSKTPSNATFRVPSVPASHNPSQVLCRADSWTPSLPSKVSVPRVPSLVPSRVGTRVLSLAPSKASLRVPSHVGSRVQSLSVSRPGSRVPSLTPSGPGSGVASLTTDSQFSSRSSLRAASQNTILSGKLVPRSSSYPLPVEGDGDRDAADEAASGRA", "length": 449 }, "evidence": [ { "id": "A0A3Q2UH76", "url": "https://omabrowser.org/oma/group/A0A3Q2UH76/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R4R5-1", "protein_name": "Coiled-coil domain containing 166", "gene_name": "Ccdc166", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKKRGQNAGRKQAGQSGEPQLSERGQYLQREYAMLSESLAVCEQRIDEVLQSNAFLNSEAQRLKEENRLFVGYVSAHALRCANAIVRLEDQNRTDLAQIRWQRAELASFYHGREDGVRAQLQEMKKRAENMTQQVQELQPYKELQLEQLARIRTLERELLHMRVEHTQLLHQVKQRFLDDKSAFEREARLHVQSLTRRAEREAALSLISHAQALKADNGRLRQELMRLLQRAQLLQNMRQQLLEQREQLRREHVDMQNLEHMHGWLHRGPGGPPLWQPPQSHQPNLRIGSFVTALDSTQHMLRAQAAPQSFSSSRVPSVDQSHRASRSPSVLSSESFPGRSLKAGSVIAPRSSSGLRSRVSSLTPSRRGSRISSVTPSRKGSTVPSMTSGPLRPREDSRLSPQPSLREMSSETDTPAKSSSKLFSGLSEDHFPLSPQLEETENTVDNTQTVLEQA", "length": 458 }, "evidence": [ { "id": "A0A3Q2UH76", "url": "https://omabrowser.org/oma/group/A0A3Q2UH76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0CW27-1", "protein_name": "Coiled-coil domain-containing protein 166", "gene_name": "CCDC166", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKKRGPSAGSQPGGAAAAGAEQPLSERAQYLQREHALLSEQLDTCEESVDQVLRENAFLDREALRLREENRLYASYVSARAQRCAKAIVRLDEQNRVDLAQIHWQRAELASLYHGREDGVRAQLLEMEARAAQMAQQVQELQPYKVLQLEQLARIRALERELLHMRVEHTQLLHRVKRRFLEDKAAFEREARQRVQSLARRAEREAVRALVAHTQAIKADNGRLRQELLLLLRRTQLLHHTRRQLLEQREQLHREHEDTRDLARVHGWLRRGPGGPPLWERPAFSQPTSRPGSLAAPISPSRAASQTPSVVPSRAAPRASSVVPSREASRVPSLVLSSMDSRVPSLATSKVGSRMPSLTASRAGSRALSLVQSLEGSGISSGSSPRVSSQDTLRSTKSGPKLLSGLSRDRDPALLPPQSEDSVNAEAAAEASPGRA", "length": 439 }, "evidence": [ { "id": "A0A3Q2UH76", "url": "https://omabrowser.org/oma/group/A0A3Q2UH76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "S4R181-1", "protein_name": "Coiled-coil domain containing 166", "gene_name": "Ccdc166", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKRGQNAGRKQETTEQPLSERAQYLQREYALLSESLVACEQRIDEVLQDNEFLNREAQRLREENRLYVGYVSAHALRCANAVVRVEDQNRMDLAQIRWQRAELASFYHGREDGVRAQLQEMKKRAENMTQRVQELQPYKELQLEQLARIRTLERELLHMRVEHTQLLHGVKRRFLDEKTAFEREARLQVQSLTRRSEREAARSLISHAQALKADNGYLRQELMRLLQRTQLLQDMRQQLLEQREQLRREHVDLKNLEQMHGWLQRGPGGPPLWQPPQSLQPSLRIGSTSHVLKAQATPQSVPTSRGQSMDLSHRPSKTPSILSSESLPGLSQKAGSVIALRSPSHPGSRVSSLTPSRKDSRVSSATPSRKGSRVPSMTSGTLRSREGSRISPQPSLREVSPEIDTPAKSSSKLPTALLEDQAPLSPQLEEAENAEDDTETVLEQA", "length": 449 }, "evidence": [ { "id": "A0A3Q2UH76", "url": "https://omabrowser.org/oma/group/A0A3Q2UH76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q2UH76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UH76" }, { "id": "PF14988", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14988" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4515", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 277, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLW3-1", "uniprot_ac": "Q5ZLW3", "uniprot_id": "DYM_CHICK", "mass": { "chemical_mass": 76161.0, "monoisotopic_mass": 76161.0 }, "refseq": { "ac": "NP_001026569", "name": "dymeclin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026569" }, "gene_names": [ { "name": "DYM", "type": "recommended", "evidence": [ { "id": "Q5ZLW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ] }, { "name": "DYM", "type": "synonym", "evidence": [ { "id": "NP_001026569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026569" } ] }, { "name": "RCJMB04_4k4", "type": "synonym", "evidence": [ { "id": "Q5ZLW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ] } ], "protein_names": [ { "name": "Dymeclin", "type": "recommended", "evidence": [ { "id": "Q5ZLW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3/entry#names_and_taxonomy" } ] }, { "name": "dymeclin", "type": "synonym", "evidence": [ { "id": "NP_001026569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026569" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719621.1, SRR13267652.22737.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000086.1. On Aug 8, 2005 this sequence version replaced XP_424452.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026569" } ] }, { "annotation": "Necessary for correct organization of Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DYM", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3", "locus": { "chromosome": "Z", "start_pos": 1564202, "end_pos": 1416644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010922", "url": "https://www.ensembl.org/id/ENSGALG00010010922" } ] } } ], "crossref": [ { "id": "Q5ZLW3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037426", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426843", "url": "https://www.ncbi.nlm.nih.gov/gene/426843", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426843", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426843", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWTLVCK", "url": "https://omabrowser.org/oma/group/VWTLVCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3ASW2", "url": "https://www.orthodb.org/?gene=A0A3Q3ASW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAV7", "url": "https://www.orthodb.org/?gene=A0A8V0YAV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLW3", "url": "https://www.orthodb.org/?gene=Q5ZLW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12895", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12895", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12895:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12895:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLW3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLW3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3ASW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ASW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ASW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ASW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLW3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGANSSSISELPDNEYLKKLSGAEPISENDPFWNQLLSFSFTTPTNSADLKLLEEATVSVCKSLVEKNPRTGNLGSLIKVFLSRTKELKISAECQNHLFIWQAHNALFIICCLLKVFISRMSEEELQLHFTYEDKTPGSYGTECEDLIEELLCCLIQLIVEIPLLDITYSISLEAVTTLIVFLSCQLFHKEILRESLIHKYLMRGRCLPYTSRLVKTLLYNFIRQERSPPPGSHVFQQQTDGGGLLYGIASGVATGLWTVFTLGGVGSKATPQLDQCSPLANQSLLLLLVLANLTDAPDTPNPYRQAIMSFKNTQDSSAFSSSHPHVFQINFNSLYTALCEQQKSDQATLLLYMLLHQNGNVRTYVLARTDIENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYAERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLDSNDSPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLEHAGAELSVERVLEIIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALYWNPRDIQLFTMDSG", "length": 669, "header": "sp|Q5ZLW3-1|DYM_CHICK Isoform 1 of Dymeclin OS=Gallus gallus OX=9031 GN=DYM PE=2 SV=1 CANONICAL=Q5ZLW3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3ASW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ASW2/entry", "sequence": { "sequence": "MGANSSSISELPDNEYLKKLSGAEPISENDPFWNQLLSFSFTTPTNSADLKLLEEATVSVCKSLVEKNPRTGNLGSLIKVFLSRTKELKISAECQNHLFIWQAHNALFIICCLLKVFISRMSEEELQLHFTYEDKTPGSYGTECEDLIEELLCCLIQLIVEIPLLDITYSISLEAVTTLIVFLSCQLFHKEILRESLIHKYLMRGRCLPYTSRLVKTLLYNFIRQERSPPPGSHVFQQQTDGGGLLYGIASGVATGLWTVFTLGGVGSKATPQLDQCSPLANQSLLLLLVLANLTDAPDTPNPYRQAIMSFKNTQDSSAFSSSHPHVFQINFNSLYTALCEQQKSDQATLLLYMLLHQNGNVRTYVLARTDIENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYAERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISYTCRHLRRYVYVLDKLYFPHSHCSTLQHCFSTLSDNGEELLSLTCSHILRSYAASLFSLLSKKHNKVLEQATQSLRGSLDSNDSPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLEHAGAELSVERVLEIIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALYWNPRDIQLFTMDSG", "length": 724, "header": "tr|A0A3Q3ASW2-1|DYM_CHICK Computationally mapped isoform of Dymeclin OS=Gallus gallus OX=9031 GN=DYM PE=2 SV=1 CANONICAL=Q5ZLW3-1" }, "locus": { "chromosome": "Z", "start_pos": 1563159, "end_pos": 1424027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026139.1", "url": "https://www.ensembl.org/id/ENSGALT00010026139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014763.1", "url": "https://www.ensembl.org/id/ENSGALP00010014763.1" } ] } }, { "isoform_ac": "A0A8V0YAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV7/entry", "sequence": { "sequence": "MGANSSSISELPDNEYLKKLSGAEPISENDPFWNQLLSFSFTTPTNSADLKLLEEATVSVCKSLVEKNPRTGNLGSLIKVFLSRTKELKISAECQNHLFIWQAHNALFIICCLLKVFISRMSEEELQLHFTYEDKTPGSYGTECEDLIEELLCCLIQLIVEIPLLDITYSISLEAVTTLIVFLSCQLFHKEILRESLIHKYLMRGRCLPYTSRLVKTLLYNFIRQERSPPPGSHVFQQQTDGGGLLYGIASGVATGLWTVFTLGGVGSKATPQLDQCSPLANQSLLLLLVLANLTDAPDTPNPYRQAIMSFKNTQDSSAFSSSHPHVFQINFNSLYTALCEQQKSDQATLLLYMLLHQNGNVRTYVLARTDIENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYAERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLDSNDSPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALYWNPRDIQLFTMDSG", "length": 631, "header": "tr|A0A8V0YAV7-1|DYM_CHICK Computationally mapped isoform of Dymeclin OS=Gallus gallus OX=9031 GN=DYM PE=2 SV=1 CANONICAL=Q5ZLW3-1" }, "locus": { "chromosome": "Z", "start_pos": 1563159, "end_pos": 1424027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026135.1", "url": "https://www.ensembl.org/id/ENSGALT00010026135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014758.1", "url": "https://www.ensembl.org/id/ENSGALP00010014758.1" } ] } }, { "isoform_ac": "Q5ZLW3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3/entry#Q5ZLW3-1", "sequence": { "sequence": "MGANSSSISELPDNEYLKKLSGAEPISENDPFWNQLLSFSFTTPTNSADLKLLEEATVSVCKSLVEKNPRTGNLGSLIKVFLSRTKELKISAECQNHLFIWQAHNALFIICCLLKVFISRMSEEELQLHFTYEDKTPGSYGTECEDLIEELLCCLIQLIVEIPLLDITYSISLEAVTTLIVFLSCQLFHKEILRESLIHKYLMRGRCLPYTSRLVKTLLYNFIRQERSPPPGSHVFQQQTDGGGLLYGIASGVATGLWTVFTLGGVGSKATPQLDQCSPLANQSLLLLLVLANLTDAPDTPNPYRQAIMSFKNTQDSSAFSSSHPHVFQINFNSLYTALCEQQKSDQATLLLYMLLHQNGNVRTYVLARTDIENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYAERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLDSNDSPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLEHAGAELSVERVLEIIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALYWNPRDIQLFTMDSG", "length": 669, "header": "sp|Q5ZLW3-1|DYM_CHICK Isoform 1 of Dymeclin OS=Gallus gallus OX=9031 GN=DYM PE=2 SV=1 CANONICAL=Q5ZLW3-1" }, "locus": { "chromosome": "Z", "start_pos": 1563159, "end_pos": 1424027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026140.1", "url": "https://www.ensembl.org/id/ENSGALT00010026140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014764.1", "url": "https://www.ensembl.org/id/ENSGALP00010014764.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426843", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426843", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JQY8-1", "protein_name": "Dymeclin", "gene_name": "DYM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSNSSRIGDLPKNEYLKKLSGTESVSENDPFWNQLLSFSFPAPTSSTELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFTYEEKSPGSYSSDSEDLLEELLCCLMQLITDIPLLDITYEISVEAVSTMVVFLSCQLFHKEVLRQSISHKYLMRGRCLPYTSKLVKTLLYNFIRQEKPPPPGAHVLPQQSDSGGLLYGLASGVATGLWTVFTLGGVGSKAAAAPELSSPLANQSLLLLLVLANLTDAADAPNPYRQAIMSFKNTQDSSPFPSSNPHAFQINFNSLYMALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVITFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNTAVGLYWNPQDIQLFTMDSD", "length": 669 }, "evidence": [ { "id": "Q5ZLW3", "url": "https://omabrowser.org/oma/group/Q5ZLW3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SU98-1", "protein_name": "Dymeclin", "gene_name": "DYM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSNSSRIGDLPKNEYLKKLSGTESVSENDPFWNQLLSFSFPAPTSSTELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFTYEEKSPGSYSSDSEDLLEELLCCLMQLITDIPLLDITYEISVEAVSTMVVFLSCQLFHKEVLRQSISHKYLMRGRCLPYTSKLVKTLLYNFIRQEKPPPPGTHVLPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKVAAASELSSPLANQSLLLLLVLANLTDAADAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYMALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVMLKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIVSLFSLLSKKHNKVLEQATQSLRGSLSSSDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVITFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKMQVFHGKEDHCAATYKTPGSMTKTFCHLHEPCPHT", "length": 655 }, "evidence": [ { "id": "Q5ZLW3", "url": "https://omabrowser.org/oma/group/Q5ZLW3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7KNA0-1", "protein_name": "Dymeclin", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGINVSRTADLGSNQWLQRFVGRQHIAHDDEAFWNGLLNYNIVLPENSQDQLNLDSRLEALCQSFIGNNLKTGNFGSLVTVFLEKTSELLSLSDQESNMHVWQTFNALFIIRSLVKYINETGSEFQLLQHFEAMPNAELLQAALEQQQQTPAESATIAMEATEQSAAAAVPVIVDGSKFETFIDALVNLIVVIPVKEFTYHLHLEAVNMLITLLSVHLFAQQPTDKSIVFRTVFKCQHANVLMSALLHFVARIVEVPHTMFGSSSAGSFVFGIAESLLSIFTFRKQPDILKAGQAAGGGELSQRFRTHYPLANQSLLLILILTNHCTAQDNAYRTSLFSCADSKDSPKQGAVSFQIDFSAVYETLCTIVTIDQATLLLYLLLHRNERFYRFVMQQQDLEQLVIPILQTLYNAPDSNSHHIYMSLIVLLILSEDEGFNKNVHTIMLKNITWYTERTISEISLGGILILIVIRTIQYNMLKMRDKYLHTNCLAALANMSGHFRALHPYVAQRLVSLFETLARKHTRLDAQLKEPADSAVFVNVSTTPEDMLQDLSVLEEVLRMVLEILNSCLTNQLVYCPNLVYTLLYKRSVFEGFRSHHAFQDVIQNIDMVVGFFSSRLQRVQEQRGELGVNEVLEVISKGASQWSSDRLRKFPDLKFKYVEEDAPEEFFIPYVWTLVCKYGCVHFSSESIKSVTTDIAC", "length": 699 }, "evidence": [ { "id": "Q5ZLW3", "url": "https://omabrowser.org/oma/group/Q5ZLW3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7RTS9-1", "protein_name": "Dymeclin", "gene_name": "DYM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSNSSRIGDLPKNEYLKKLSGTESISENDPFWNQLLSFSFPAPTSSSELKLLEEATISVCRSLVENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICQMSEEELQLHFTYEEKSPGNYSSDSEDLLEELLCCLMQLITDIPLLDITYEISVEAISTMVVFLSCQLFHKEVLRQSISHKYLMRGPCLPYTSKLVKTLLYNFIRQEKPPPPGAHVFPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKAAASPELSSPLANQSLLLLLVLANLTDASDAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFTMDSD", "length": 669 }, "evidence": [ { "id": "Q5ZLW3", "url": "https://omabrowser.org/oma/group/Q5ZLW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 669, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLW3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q1T765-1", "uniprot_ac": "Q1T765", "uniprot_id": "CENPN_CHICK", "mass": { "chemical_mass": 40344.0, "monoisotopic_mass": 40344.0 }, "refseq": { "ac": "NP_001038135", "name": "centromere protein N isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" }, "gene_names": [ { "name": "CENPN", "type": "recommended", "evidence": [ { "id": "Q1T765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ] }, { "name": "CENP-N", "type": "synonym", "evidence": [ { "id": "NP_001038135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" } ] }, { "name": "CENPN", "type": "synonym", "evidence": [ { "id": "NP_001038135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" } ] } ], "protein_names": [ { "name": "Centromere protein N", "type": "recommended", "evidence": [ { "id": "Q1T765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T765/entry#names_and_taxonomy" } ] }, { "name": "CENP-N", "type": "synonym", "evidence": [ { "id": "Q1T765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T765/entry#names_and_taxonomy" } ] }, { "name": "centromere protein N isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001038135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01064543.1, SRR12888512.948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Dec 14, 2021 this sequence version replaced XP_040563072.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" } ] }, { "annotation": "Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765#function" } ] }, { "annotation": "The CENP-H-I complex may function, in part, as a marker directing CENP-A deposition to centromeres.[CENPA, CENPI]", "evidence": [ { "database": "RefSeq", "id": "NP_001038135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" }, { "database": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CENPN", "url": "https://www.uniprot.org/uniprotkb/Q1T765", "locus": { "chromosome": "11", "start_pos": 15022181, "end_pos": 15014558, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007859", "url": "https://www.ensembl.org/id/ENSGALG00010007859" } ] } } ], "crossref": [ { "id": "Q1T765", "url": "https://alphafold.ebi.ac.uk/entry/Q1T765", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013494", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013494", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "693246", "url": "https://www.ncbi.nlm.nih.gov/gene/693246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "7BXT", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7BXT&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "Q1T765", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q1T765*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR007902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:693246", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:693246", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSVYQMK", "url": "https://omabrowser.org/oma/group/WSVYQMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452J7Y9", "url": "https://www.orthodb.org/?gene=A0A452J7Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XW75", "url": "https://www.orthodb.org/?gene=A0A8V0XW75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q1T765", "url": "https://www.orthodb.org/?gene=Q1T765", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46790", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46790", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46790:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46790:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00007bxt", "url": "https://www.rcsb.org/structure/pdb_00007bxt", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7BXT", "url": "https://www.rcsb.org/structure/7BXT", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF05238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q1T765", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q1T765", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001038135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452J7Y9", "url": "https://www.uniprot.org/uniprotkb/A0A452J7Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452J7Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452J7Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1T765-1", "url": "https://www.uniprot.org/uniprotkb/Q1T765-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEVIVEYIRRTVLKIPRDEIMAVLQKWGFLSEAQLQTINFRQTKEGISHSVAQLCEESSADLKQAALLDIIYNHIYPNKRVWSVYHMNKTGEETDFFDFRDFKKKFRRQIQSALINVTINFREYEDNAIWIRIAWGTPYTKPNQYKTSYVVYHSQTPYVFISASVLRSNLPLLCQAMVVASNYHDIHEMELRSHCLNSLKDIVFKRYSQNFQTNYPLQERNVLTENVDLRINDENRSEKERIYRLNQESFGNGPQPKLDFAQYKLETMFKSDPKWDVLEKKEPFRCLVKFSSPHLLESLKSLAPAGLADAPLSPLLTCIPQKARNYFKIREKKSLHPGSFVSP", "length": 344, "header": "sp|Q1T765-1|CENPN_CHICK Isoform 1 of Centromere protein N OS=Gallus gallus OX=9031 GN=CENPN PE=1 SV=1 CANONICAL=Q1T765-1" }, "isoforms": [ { "isoform_ac": "A0A452J7Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452J7Y9/entry", "sequence": { "sequence": "MDEVIVEYIRRTVLKIPRDEIMAVLQKWGFLSEAQLQTINFRQTKEGISHSVAQLCEESSADLKQAALLDIIYNHIYPNKRVWSVYHMNKTGEETDFFDFRDFKKKFRRQIQSALINVTINFREYEDNAIWIRIAWGTPYTKPNQYKTSYVVYHSQTPYVFISASVLRSNLPLLCQAMVVASNYHDIHEMELRSHCLNSLKDIVFKRYSQNFQTNYPLQERNVLTENVDLRINDENRSEKERIYRLNQESFGNGPQPKLDFAQYKLETMFKSDPKWDVLEKKEPFRCLVKFSSPHLLESLKSLAPAGLADAPLSPLLTCIPQKARNYFKIREKKSLHPGSFMQITFKDHCRV", "length": 352, "header": "tr|A0A452J7Y9-1|CENPN_CHICK Computationally mapped isoform of Centromere protein N OS=Gallus gallus OX=9031 GN=CENPN PE=1 SV=1 CANONICAL=Q1T765-1" }, "locus": { "chromosome": "11", "start_pos": 15021548, "end_pos": 15015006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018705.1", "url": "https://www.ensembl.org/id/ENSGALT00010018705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010255.1", "url": "https://www.ensembl.org/id/ENSGALP00010010255.1" } ] } }, { "isoform_ac": "A0A8V0XW75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW75/entry", "sequence": { "sequence": "MDEVIVEYIRRTVLKIPRDEIMAVLQKWGFLSEAQLQTINFRQTKEGISHSVAQLCEESSADLKQAALLDIIYNHIYPNKRVWSVYHMNKTGEETDFFDFRDFKKKFRRQIQSALINVTINFREYEDNAIWIRIAWGTPYTKPNQYKTSYVVYHSQTPYVFISASVLRSNLPLLCQAMVVASNYHDIHEMELRSHCLNSLKDIVFKRYSQNFQTNYPLQERNVLTENVDLRINDENRSEKERIYRLNQESFGNGPQPKLDFAQYKLETMFKSDPKWDVLEKKEPFRCLVKFSSPHLLESLKSLAPAGKYSNSVKREEKSTVKHFNHFTFCLCIA", "length": 334, "header": "tr|A0A8V0XW75-1|CENPN_CHICK Computationally mapped isoform of Centromere protein N OS=Gallus gallus OX=9031 GN=CENPN PE=1 SV=1 CANONICAL=Q1T765-1" }, "locus": { "chromosome": "11", "start_pos": 15020769, "end_pos": 15015006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018709.1", "url": "https://www.ensembl.org/id/ENSGALT00010018709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010259.1", "url": "https://www.ensembl.org/id/ENSGALP00010010259.1" } ] } }, { "isoform_ac": "Q1T765-1", "url": "https://www.uniprot.org/uniprotkb/Q1T765/entry#Q1T765-1", "sequence": { "sequence": "MDEVIVEYIRRTVLKIPRDEIMAVLQKWGFLSEAQLQTINFRQTKEGISHSVAQLCEESSADLKQAALLDIIYNHIYPNKRVWSVYHMNKTGEETDFFDFRDFKKKFRRQIQSALINVTINFREYEDNAIWIRIAWGTPYTKPNQYKTSYVVYHSQTPYVFISASVLRSNLPLLCQAMVVASNYHDIHEMELRSHCLNSLKDIVFKRYSQNFQTNYPLQERNVLTENVDLRINDENRSEKERIYRLNQESFGNGPQPKLDFAQYKLETMFKSDPKWDVLEKKEPFRCLVKFSSPHLLESLKSLAPAGLADAPLSPLLTCIPQKARNYFKIREKKSLHPGSFVSP", "length": 344, "header": "sp|Q1T765-1|CENPN_CHICK Isoform 1 of Centromere protein N OS=Gallus gallus OX=9031 GN=CENPN PE=1 SV=1 CANONICAL=Q1T765-1" }, "locus": { "chromosome": "11", "start_pos": 15021074, "end_pos": 15015006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018712.1", "url": "https://www.ensembl.org/id/ENSGALT00010018712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010262.1", "url": "https://www.ensembl.org/id/ENSGALP00010010262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.", "journal": "Nat. Cell Biol.", "date": "2006", "authors": "Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" }, { "database": "RefSeq", "id": "NP_001038135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038135" } ], "reference": [ { "type": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "pathway": [ { "id": "gga:693246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:693246", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SYA1-1", "protein_name": "Centromere protein N", "gene_name": "CENPN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDIVAEFFRRTILKIPMTEMMTILKAWDFLSESQLQAVNFRQRKESLAQDLVLLCQEKRARLQDAALLDIIYTQFHRHQKVWDAFQMSKGAGGDTDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENAVWIRIAWGTQYRKPNQYKPTYVVYYSQAPYAFISSSQLKSNLPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQNFETHNSSIPLQERSLGLDIHMDSRIIHENRIEKERVQGVTREIFGDYPQPRLEFAQYKLETKFRSDLNGGILADREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPSKGMNYFKIRDK", "length": 339 }, "evidence": [ { "id": "Q1T765", "url": "https://omabrowser.org/oma/group/Q1T765/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MXD2-1", "protein_name": "Centromere protein N isoform X1", "gene_name": "Cenpn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDENVAEFIRRSILKIPLCEMKTILKAWNFLSEDQLQTINFRQRKEFLAQEVILMCEEKCARLDDMALLDIVYTQVHRHRKLWNVFEMSKEPGEDVDLFDMKWFQCSFKKILQRALRNVTVSFRVDGKNAVWIRIAWGTQYSQPNQYKPTFVVYYPQTPYAFISSCHLKSNVPLLHQALKVASKHHQIVQMDLRSRHLDSLKAIVFREYDQTFESHNSTVPLQEGNLGLDMNLDSNIIHENLEEKERIHRVTQETFGAHPQPQLEFAQYKLETKFKSGISGGILADRKEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIANKKMNYFKIRDK", "length": 339 }, "evidence": [ { "id": "Q1T765", "url": "https://omabrowser.org/oma/group/Q1T765/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5U2W4-1", "protein_name": "Centromere protein N", "gene_name": "Cenpn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDENVAEFLRRIILKIPLCEMKTILEAWDFLSEDQLQSINLKQRKEFLAQEVILLCEDKCASLDDMALLDLMYTQFHRHQKLWNVFQMSKEPGGNDVDLFDMEQFQSSFKRILQRALKNVTVSFRVYEKNSVWIRVAWGTQYSQPNQYKPTFVVYYPQTPYVFISSCYLKSTVPLLHQALKVASKHHQMAQLDLRSRHLDSLTAIVFNEYDQTFENYNSTASWREGSLGLKTDLDSKIIHENTEEKVRIHRATQEAFGAYPQPQLEFAQYKLETKFKSDVGGGILADRKEPLRCLVKFSSPHLLEALKSLAPAGIADTPLSPLLTCIPSKKMNYFKIRDK", "length": 340 }, "evidence": [ { "id": "Q1T765", "url": "https://omabrowser.org/oma/group/Q1T765/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96H22-1", "protein_name": "Centromere protein N", "gene_name": "CENPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK", "length": 339 }, "evidence": [ { "id": "Q1T765", "url": "https://omabrowser.org/oma/group/Q1T765/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZW2-1", "protein_name": "Centromere protein N", "gene_name": "Cenpn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKENVAEFLRRTILKIPLSEMKSILEAWDFLSEDQLQTINLKQRKDYLAQEVILLCEDKRASLDDVVLLDIVYTQFHRHQKLWNVFQMSKEPGEDVDLFDMEQFQSSFKRILQRALKNVTVSFRVYEKDSVWIRVAWGTQYSQPNQYKPTFVVYYPQTPYAFISSCHLKNTVPLLHQALKVASKHHQIVHLDLRSRHLDSLKAIVFREYNQTCENYSSTTSLQEASLSMCLDSKITHENTEEKVRVHRVTQETFGTYPQPQLEFAQYKLETKFKSNIGGGLLADRKEPFRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPSKKMNYFKIRDK", "length": 337 }, "evidence": [ { "id": "Q1T765", "url": "https://omabrowser.org/oma/group/Q1T765/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "Q1T765", "url": "https://www.uniprot.org/uniprotkb/Q1T765" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { 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introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000023.1. 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F359-1", "uniprot_ac": "Q5F359", "uniprot_id": "TPPC5_CHICK", "mass": { "chemical_mass": 21018.0, "monoisotopic_mass": 21018.0 }, "refseq": { "ac": "NP_001258088", "name": "trafficking protein particle complex subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258088" }, "gene_names": [ { "name": "TRAPPC5", "type": "recommended", "evidence": [ { "id": "Q5F359", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ] }, { "name": "RCJMB04_33f11", "type": "synonym", "evidence": [ { "id": "Q5F359", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ] }, { "name": "TRAPPC5", "type": "synonym", "evidence": [ { "id": "NP_001258088", "database": "RefSeq", "url": 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The reference sequence was derived from JAENSK010000386.1. On Sep 5, 2012 this sequence version replaced XP_003643602.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001258088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258088" } ] }, { "annotation": "May play a role in vesicular transport from endoplasmic reticulum to Golgi.", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359#function" }, { "database": "UniProtKB", "id": "A0A8V0XE83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE83#function" }, { "database": "UniProtKB", "id": "ARBA00002910", "url": "https://www.uniprot.org/uniprotkb/ARBA00002910#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC5", "url": "https://www.uniprot.org/uniprotkb/Q5F359", "locus": { "chromosome": "30", "start_pos": 59769, "end_pos": 54637, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003680", "url": "https://www.ensembl.org/id/ENSGALG00010003680" } ] } } ], "crossref": [ { "id": "Q5F359", "url": "https://alphafold.ebi.ac.uk/entry/Q5F359", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858483", "url": "https://www.ncbi.nlm.nih.gov/gene/100858483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTEVTVW", "url": "https://omabrowser.org/oma/group/KTEVTVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XE83", "url": "https://www.orthodb.org/?gene=A0A8V0XE83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5F359", "url": "https://www.orthodb.org/?gene=Q5F359", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20902:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20902:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F359", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F359", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001258088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XE83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XE83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F359-1", "url": "https://www.uniprot.org/uniprotkb/Q5F359-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESRFTRGKSPLLERPLGRPRGEVSLSAFALLFCELVQYCQRRVYSVAELQSKLAQLGHQVGLRLLDPLVSRERGGRRETKVLSVLLFVKGPVWRALFGKEADKLEQANDDDKTYYVIEREPLVNTFISVPRENSTLNCAAFTAGLVEAVLGASGFPAKVTAHWHKGTTLMIKFEEGVIARDKSLEGR", "length": 188, "header": "sp|Q5F359-1|TPPC5_CHICK Isoform 1 of Trafficking protein particle complex subunit 5 OS=Gallus gallus OX=9031 GN=TRAPPC5 PE=2 SV=1 CANONICAL=Q5F359-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XE83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE83/entry", "sequence": { "sequence": "MGFLYGSPLWGLSMGSLWVTLWDLCGISLWVSLWDLWVSVGHSVGSVGLHGSPWGSAPPERHVHPPFRLGAELSAPGPAPSAPARPSLPPRSGRRFYDSGGRKAEAQRFYDSGGRKATERNDNSVGGPMESRFTRGKSPLLERPLGRPRGEVSLSAFALLFCELVQYCQRRVYSVAELQSKLAQLGHQVGLRLLDPLVSRERGGRRETKVLSVLLFVKGPVWRALFGKEADKLEQANDDDKTYYVIEREPLVNTFISVPRENSTLNCAAFTAGLVEAVLGASGFPAKVTAHWHKGTTLMIKFEEGVIARDKSLEGR", "length": 316, "header": "tr|A0A8V0XE83-1|TPPC5_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 5 OS=Gallus gallus OX=9031 GN=TRAPPC5 PE=2 SV=1 CANONICAL=Q5F359-1" }, "locus": { "chromosome": "30", "start_pos": 57656, "end_pos": 54836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008525.1", "url": "https://www.ensembl.org/id/ENSGALT00010008525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004988.1", "url": "https://www.ensembl.org/id/ENSGALP00010004988.1" } ] } }, { "isoform_ac": "Q5F359-1", "url": "https://www.uniprot.org/uniprotkb/Q5F359/entry#Q5F359-1", "sequence": { "sequence": "MESRFTRGKSPLLERPLGRPRGEVSLSAFALLFCELVQYCQRRVYSVAELQSKLAQLGHQVGLRLLDPLVSRERGGRRETKVLSVLLFVKGPVWRALFGKEADKLEQANDDDKTYYVIEREPLVNTFISVPRENSTLNCAAFTAGLVEAVLGASGFPAKVTAHWHKGTTLMIKFEEGVIARDKSLEGR", "length": 188, "header": "sp|Q5F359-1|TPPC5_CHICK Isoform 1 of Trafficking protein particle complex subunit 5 OS=Gallus gallus OX=9031 GN=TRAPPC5 PE=2 SV=1 CANONICAL=Q5F359-1" }, "locus": { "chromosome": "30", "start_pos": 59769, "end_pos": 59399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008518.1", "url": "https://www.ensembl.org/id/ENSGALT00010008518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004985.1", "url": "https://www.ensembl.org/id/ENSGALP00010004985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:100858483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858483", "resource": "KEGG Pathway" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "TRAPPI protein complex", "id": "GO:1990070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990070", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q5F359", "url": "https://www.uniprot.org/uniprotkb/Q5F359" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F359-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 188, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F359-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F359" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLJ4-1", "uniprot_ac": "Q5ZLJ4", "uniprot_id": "TMM70_CHICK", "mass": { "chemical_mass": 27432.0, "monoisotopic_mass": 27432.0 }, "refseq": { "ac": "NP_001012866", "name": "transmembrane protein 70, mitochondrial precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866" }, "gene_names": [ { "name": "TMEM70", "type": "recommended", "evidence": [ { "id": "Q5ZLJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ] }, { "name": "RCJMB04_5o22", "type": "synonym", "evidence": [ { "id": "Q5ZLJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ] }, { "name": "TMEM70", "type": "synonym", "evidence": [ { "id": "NP_001012866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866" } ] } ], "protein_names": [ { "name": "Transmembrane protein 70, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q5ZLJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 70, mitochondrial precursor", "type": "synonym", "evidence": [ { "id": "NP_001012866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866" } ] }, { "name": "transmembrane protein 70, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001012866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719740.1, SRR12888529.341399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000043.1. On Mar 14, 2005 this sequence version replaced XP_418300.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866" } ] }, { "annotation": "Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4#function" }, { "database": "UniProtKB", "id": "Q9BUB7", "url": "https://www.uniprot.org/uniprotkb/Q9BUB7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM70", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4", "locus": { "chromosome": "2", "start_pos": 117749021, "end_pos": 117744589, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003860", "url": "https://www.ensembl.org/id/ENSGALG00010003860" } ] } } ], "crossref": [ { "id": "Q5ZLJ4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "420188", "url": "https://www.ncbi.nlm.nih.gov/gene/420188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420188", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTFYVKR", "url": "https://omabrowser.org/oma/group/TTFYVKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHR0", "url": "https://www.orthodb.org/?gene=A0A8V0XHR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLJ4", "url": "https://www.orthodb.org/?gene=Q5ZLJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13281:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13281:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLJ4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLJ4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XHR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLJ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLRAAGCWRAAASRPGPVWLRGAEHRGLPLASRRLGLPLPLPLAAGGRRLRSGCGALPEVASFQGVAVRSLSTSAPSDHPEHGRLVYKGNLAKAVLGVRFFSYSTSIFNLFMAPYLMLKTGIGFDSLFLQAAFYGLIGFFTFVTPVTLHILTKGYVIRLYYKEEMDTYTAITYNAILAEKATVFHQKDVKIPDITKMFTTFYAKTKSMLVNPTLFPDPQDYNRLMGYDKAFCFDFEEEEKDGESK", "length": 246, "header": "sp|Q5ZLJ4-1|TMM70_CHICK Isoform 1 of Transmembrane protein 70, mitochondrial OS=Gallus gallus OX=9031 GN=TMEM70 PE=2 SV=1 CANONICAL=Q5ZLJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHR0/entry", "sequence": { "sequence": "MITAAAASGSVTPVGESRAGPSCGGTKGWGCAAAAEAALVHRAVPVPFRSVPFPARLAVGCCGTGRGCHAAPRRRLLACRRLPARPRLAAGCGAPWAPACQPPSGPAPASASGRGGTAAAERLRGAPRGVRFFSYSTSIFNLFMAPYLMLKTGIGFDSLFLQAAFYGLIGFFTFVTPVTLHILTKGYVIRLYYKEEMDTYTAITYNAILAEKATVFHQKDVKIPDITKMFTTFYAKTKSMLVNPTLFPDPQDYNRLMGYDKAFCFDFEEEEKDGESK", "length": 277, "header": "tr|A0A8V0XHR0-1|TMM70_CHICK Computationally mapped isoform of Transmembrane protein 70, mitochondrial OS=Gallus gallus OX=9031 GN=TMEM70 PE=2 SV=1 CANONICAL=Q5ZLJ4-1" }, "locus": { "chromosome": "2", "start_pos": 117747721, "end_pos": 117744788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008933.1", "url": "https://www.ensembl.org/id/ENSGALT00010008933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005268.1", "url": "https://www.ensembl.org/id/ENSGALP00010005268.1" } ] } }, { "isoform_ac": "Q5ZLJ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4/entry#Q5ZLJ4-1", "sequence": { "sequence": "MLLRAAGCWRAAASRPGPVWLRGAEHRGLPLASRRLGLPLPLPLAAGGRRLRSGCGALPEVASFQGVAVRSLSTSAPSDHPEHGRLVYKGNLAKAVLGVRFFSYSTSIFNLFMAPYLMLKTGIGFDSLFLQAAFYGLIGFFTFVTPVTLHILTKGYVIRLYYKEEMDTYTAITYNAILAEKATVFHQKDVKIPDITKMFTTFYAKTKSMLVNPTLFPDPQDYNRLMGYDKAFCFDFEEEEKDGESK", "length": 246, "header": "sp|Q5ZLJ4-1|TMM70_CHICK Isoform 1 of Transmembrane protein 70, mitochondrial OS=Gallus gallus OX=9031 GN=TMEM70 PE=2 SV=1 CANONICAL=Q5ZLJ4-1" }, "locus": { "chromosome": "2", "start_pos": 117747721, "end_pos": 117744993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008930.1", "url": "https://www.ensembl.org/id/ENSGALT00010008930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005266.1", "url": "https://www.ensembl.org/id/ENSGALP00010005266.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:420188", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420188", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "mitochondrial crista", "id": "GO:0030061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030061", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "mitochondrial proton-transporting ATP synthase complex assembly", "id": "GO:0033615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033615", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mitochondrial proton-transporting ATP synthase complex binding", "id": "GO:0140260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140260", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLJ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLJ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLJ4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3Z3-1", "uniprot_ac": "Q5F3Z3", "uniprot_id": "UB2V2_CHICK", "mass": { "chemical_mass": 16305.0, "monoisotopic_mass": 16305.0 }, "refseq": { "ac": "NP_001026189", "name": "ubiquitin-conjugating enzyme E2 variant 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026189" }, "gene_names": [ { "name": "UBE2V2", "type": "recommended", "evidence": [ { "id": "Q5F3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3" } ] }, { "name": "RCJMB04_4b12", "type": "synonym", "evidence": [ { "id": "Q5F3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3" } ] }, { "name": "UBE2V2", "type": "synonym", "evidence": [ { "id": "NP_001026189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026189" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2 variant 2", "type": "recommended", "evidence": [ { "id": "Q5F3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 variant 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026189" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851507.1, HAEK01000071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000043.1. On Aug 8, 2005 this sequence version replaced XP_419193.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026189" } ] }, { "annotation": "Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z3", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z3", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2V2", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3", "locus": { "chromosome": "2", "start_pos": 107740554, "end_pos": 107705806, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005441", "url": "https://www.ensembl.org/id/ENSGALG00010005441" } ] } } ], "crossref": [ { "id": "Q5F3Z3", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3Z3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23807", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23807", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421109", "url": "https://www.ncbi.nlm.nih.gov/gene/421109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421109", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWSREST", "url": "https://omabrowser.org/oma/group/NWSREST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XNV9", "url": 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}, { "id": "R-GGA-5693571", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69473", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026189", "url": 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"MAGSTVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "length": 144, "header": "sp|Q5F3Z3-1|UB2V2_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallus gallus OX=9031 GN=UBE2V2 PE=2 SV=1 CANONICAL=Q5F3Z3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNV9/entry", "sequence": { "sequence": "KQIQTGNVPYALKIHSRIAIKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "length": 158, "header": "tr|A0A8V0XNV9-1|UB2V2_CHICK Computationally mapped isoform of Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallus gallus OX=9031 GN=UBE2V2 PE=2 SV=1 CANONICAL=Q5F3Z3-1" }, "locus": { "chromosome": "2", "start_pos": 107735491, "end_pos": 107724623, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012977.1", "url": "https://www.ensembl.org/id/ENSGALT00010012977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007539.1", "url": "https://www.ensembl.org/id/ENSGALP00010007539.1" } ] } }, { "isoform_ac": "A0A8V0XRK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRK9/entry", "sequence": { "sequence": "MNPVSVTSIESVEWNVMVAVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "length": 158, "header": "tr|A0A8V0XRK9-1|UB2V2_CHICK Computationally mapped isoform of Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallus gallus OX=9031 GN=UBE2V2 PE=2 SV=1 CANONICAL=Q5F3Z3-1" }, "locus": { "chromosome": "2", "start_pos": 107735491, "end_pos": 107706568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012978.1", "url": "https://www.ensembl.org/id/ENSGALT00010012978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007540.1", "url": "https://www.ensembl.org/id/ENSGALP00010007540.1" } ] } }, { "isoform_ac": "Q5F3Z3-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3/entry#Q5F3Z3-1", "sequence": { "sequence": "MAGSTVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "length": 144, "header": "sp|Q5F3Z3-1|UB2V2_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallus gallus OX=9031 GN=UBE2V2 PE=2 SV=1 CANONICAL=Q5F3Z3-1" }, "locus": { "chromosome": "2", "start_pos": 107735491, "end_pos": 107705841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012979.1", "url": "https://www.ensembl.org/id/ENSGALT00010012979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007541.1", "url": "https://www.ensembl.org/id/ENSGALP00010007541.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z3", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421109", "resource": "KEGG Pathway" }, { "id": "R-GGA-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" }, { "id": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHC8-1", "protein_name": "Ubiquitin conjugating enzyme E2 V2", "gene_name": "UBE2V2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FKRDVPFSCLVPVCVLGLAGEEEVLQSQRGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKIECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "length": 169 }, "evidence": [ { "id": "Q5F3Z3", "url": "https://omabrowser.org/oma/group/Q5F3Z3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZKP2-1", "uniprot_ac": "Q5ZKP2", "uniprot_id": "MMAD_CHICK", "mass": { "chemical_mass": 33131.0, "monoisotopic_mass": 33131.0 }, "refseq": { "ac": "NP_001008477", "name": "cobalamin trafficking protein CblD precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" }, "gene_names": [ { "name": "MMADHC", "type": "recommended", "evidence": [ { "id": "Q5ZKP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ] }, { "name": "C2orf25", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "CblD", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "MMADHC", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "RCJMB04_9n6", "type": "synonym", "evidence": [ { "id": "Q5ZKP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ] } ], "protein_names": [ { "name": "Cobalamin trafficking protein CblD", "type": "recommended", "evidence": [ { "id": "Q5ZKP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2/entry#names_and_taxonomy" } ] }, { "name": "CblD", "type": "synonym", "evidence": [ { "id": "Q5ZKP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2/entry#names_and_taxonomy" } ] }, { "name": "Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "Q5ZKP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2/entry#names_and_taxonomy" } ] }, { "name": "cobalamin trafficking protein CblD precursor", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "cobalamin trafficking protein CblD", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "name": "methylmalonic aciduria and homocystinuria type D homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001008477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720042.1, HAEL01005376.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Dec 16, 2004 this sequence version replaced XP_422157.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477" } ] }, { "annotation": "Involved in cobalamin metabolism and trafficking. Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl). Promotes oxidation of cob(II)alamin bound to MMACHC. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2#function" }, { "database": "UniProtKB", "id": "Q9H3L0", "url": "https://www.uniprot.org/uniprotkb/Q9H3L0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MMADHC", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2", "locus": { "chromosome": "7", "start_pos": 34532159, "end_pos": 34545898, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009609", "url": "https://www.ensembl.org/id/ENSGALG00010009609" } ] } } ], "crossref": [ { "id": "Q5ZKP2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012473", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424311", "url": "https://www.ncbi.nlm.nih.gov/gene/424311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424311", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PECCGMI", "url": "https://omabrowser.org/oma/group/PECCGMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6Q1", "url": "https://www.orthodb.org/?gene=A0A8V0Y6Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKP2", "url": "https://www.orthodb.org/?gene=Q5ZKP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13192:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13192:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKP2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKP2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9759218", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9759218", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001008477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKP2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANVLCNRARLVTYLPGFYSLVKRVVNPKAFSTAGSSGSDEPHVAATPPDLCPRTVWPDEVMGPFGPQDQRFQLPGNIGFDCHLNGTAAQRKSQASKSLPDILAEPSPNERHEFVMAQYINEFQGSDVPQKQQVNNAETYFENAKVECAVQACPELLRKDFESMFPEVNANHLTVLTVTQKTKNDMTVWSQEVEDEREMLLENFINGAKEICYAICSEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHFGFSVDDLGCCKVIRHNIWGTHVVVGSIFTNAEPDSPIMRKLSGN", "length": 296, "header": "sp|Q5ZKP2-1|MMAD_CHICK Isoform 1 of Cobalamin trafficking protein CblD OS=Gallus gallus OX=9031 GN=MMADHC PE=2 SV=1 CANONICAL=Q5ZKP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q1/entry", "sequence": { "sequence": "MANVLCNRARLVTYLPGFYSLVKRVVNPKAFSTAGSSGSDEPHVAATPPDLCPRTVWPDEVMGPFGPQDQRFQLPGNIGFDCHLNGTAAQRKSQASKSLPDILAEPSPNERHEFVMAQYINEFQGSDVPQKQQVNNAETYFENAKVECAVQACPELLRKDFESMFPEVNANHLTVLTVTQKTKNDMTVWSQEVEDEREMLLENFINGAKEICYAICSEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHFGFSVDDLGCCKVIRHNIWAESYVSCYPGEVLHCCEVKNPILLPPAATWLELKCSK", "length": 307, "header": "tr|A0A8V0Y6Q1-1|MMAD_CHICK Computationally mapped isoform of Cobalamin trafficking protein CblD OS=Gallus gallus OX=9031 GN=MMADHC PE=2 SV=1 CANONICAL=Q5ZKP2-1" }, "locus": { "chromosome": "7", "start_pos": 34545691, "end_pos": 34532671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022916.1", "url": "https://www.ensembl.org/id/ENSGALT00010022916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013244.1", "url": "https://www.ensembl.org/id/ENSGALP00010013244.1" } ] } }, { "isoform_ac": "Q5ZKP2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2/entry#Q5ZKP2-1", "sequence": { "sequence": "MANVLCNRARLVTYLPGFYSLVKRVVNPKAFSTAGSSGSDEPHVAATPPDLCPRTVWPDEVMGPFGPQDQRFQLPGNIGFDCHLNGTAAQRKSQASKSLPDILAEPSPNERHEFVMAQYINEFQGSDVPQKQQVNNAETYFENAKVECAVQACPELLRKDFESMFPEVNANHLTVLTVTQKTKNDMTVWSQEVEDEREMLLENFINGAKEICYAICSEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHFGFSVDDLGCCKVIRHNIWGTHVVVGSIFTNAEPDSPIMRKLSGN", "length": 296, "header": "sp|Q5ZKP2-1|MMAD_CHICK Isoform 1 of Cobalamin trafficking protein CblD OS=Gallus gallus OX=9031 GN=MMADHC PE=2 SV=1 CANONICAL=Q5ZKP2-1" }, "locus": { "chromosome": "7", "start_pos": 34545691, "end_pos": 34535675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022912.1", "url": "https://www.ensembl.org/id/ENSGALT00010022912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013242.1", "url": "https://www.ensembl.org/id/ENSGALP00010013242.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424311", "resource": "KEGG Pathway" }, { "id": "R-GGA-9759218", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9759218", "resource": "Reactome", "description": "Cobalamin (Cbl) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G878-1", "protein_name": "Cobalamin trafficking protein CblD isoform X3", "gene_name": "Mmadhc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVPARGLPCTSRGDRNPAGFFAKGRNLRPSSSLEMAHVLCNRARLVSYLPGFCSLVKRVISPKAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRFQLPGNMGFDCHLNGTASQKKSLTHKTLPDVLAEPLSTERHEFVMAQYVNEFQSSDAPVEQEINSAETYFESARVECVIQTCPELLQRDFETLFPEVANNKLMILTVTQKTENDMTAWSEEVEVEREMLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVFVGSIFTNAAADSHIMRKLSGN", "length": 330 }, "evidence": [ { "id": "Q5ZKP2", "url": "https://omabrowser.org/oma/group/Q5ZKP2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0UYB6-1", "protein_name": "Metabolism of cobalamin associated Db", "gene_name": "mmadhcb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASVLCSRARLVTYLPGLHVLVHRVVGARSFSGASGSDEPHLNTSTPDIAPRTVWPDESMGPFGPQDKRFQLPGNVGFDCHLESPVEQRTTSVHSVMPDVLTAQSNNQRHDFILAQFINELHEDDKTSTAQNMDKAEQFFDHSSVECAIQSCPELLKRDFESMFPEAPSTGMMVVTVTQRTQNDMTAWTEQVDQEREELLAKFIEGAKEICHALRNEGFWADFIDPSSGLAYFGSYTNNTLFETDDRYRHLGFQIEDLGCCKVIRHVMWGTHAFVGTLFTSAPPNSQIMKKLQGDLS", "length": 297 }, "evidence": [ { "id": "Q5ZKP2", "url": "https://omabrowser.org/oma/group/Q5ZKP2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LE45-1", "protein_name": "Metabolism of cobalamin associated D", "gene_name": "MMADHC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANVLCNRARLVSYLPGFCSLVKKVVNPRAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTTSQKKSQVHRTLPDILAEPLSSERHEFVMAQYVNEFQNNDAPVEQEINSAETYFESAKVECAIQTCPELLRKDFESLFPEVATNKLMILTVTQKTKNDMTVWSEEVENEREMLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMRKLSGN", "length": 296 }, "evidence": [ { "id": "Q5ZKP2", "url": "https://omabrowser.org/oma/group/Q5ZKP2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99LS1-1", "protein_name": "Cobalamin trafficking protein CblD", "gene_name": "Mmadhc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHVLCNRARLVSYLPGFCSLVKRVINPRAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSQAHKTLPDVLAEPLSTERHEFVMAQYVNEFQDSDAPVEQEINSAETYFESAKVECAIQTCPELLRRDFESLFPEVANSKLMILTVTQKTENDMTVWSEEVEVEREVLLEKFISGAKEICYALRAEGYWADFIDPSSGVAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATADSSIMRKLSGN", "length": 296 }, "evidence": [ { "id": "Q5ZKP2", "url": "https://omabrowser.org/oma/group/Q5ZKP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3L0-1", "protein_name": "Cobalamin trafficking protein CblD", "gene_name": "MMADHC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANVLCNRARLVSYLPGFCSLVKRVVNPKAFSTAGSSGSDESHVAAAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYVNEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQKTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN", "length": 296 }, "evidence": [ { "id": "Q5ZKP2", "url": "https://omabrowser.org/oma/group/Q5ZKP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKP2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZI42-1", "uniprot_ac": "Q5ZI42", "uniprot_id": "MCTS1_CHICK", "mass": { "chemical_mass": 20571.0, "monoisotopic_mass": 20571.0 }, "refseq": { "ac": "NP_001099145", "name": "malignant T-cell-amplified sequence 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" }, "gene_names": [ { "name": "MCTS1", "type": "recommended", "evidence": [ { "id": "Q5ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ] }, { "name": "MCTS1", "type": "synonym", "evidence": [ { "id": "NP_001099145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" } ] }, { "name": "RCJMB04_30h12", "type": "synonym", "evidence": [ { "id": "Q5ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ] } ], "protein_names": [ { "name": "Malignant T-cell-amplified sequence 1", "type": "recommended", "evidence": [ { "id": "Q5ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42/entry#names_and_taxonomy" } ] }, { "name": "MCT-1", "type": "synonym", "evidence": [ { "id": "NP_001099145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" }, { "id": "Q5ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42/entry#names_and_taxonomy" } ] }, { "name": "malignant T-cell amplified sequence 1", "type": "synonym", "evidence": [ { "id": "NP_001099145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" } ] }, { "name": "malignant T-cell-amplified sequence 1", "type": "synonym", "evidence": [ { "id": "NP_001099145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720942.1, HAEK01045234.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Oct 2, 2007 this sequence version replaced XP_420334.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001099145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" } ] }, { "annotation": "Altered expression of lactate dehydrogenase and monocarboxylate transporter involved in lactate metabolism in broiler wooden breast.", "evidence": [ { "database": "RefSeq", "id": "NP_001099145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" }, { "database": "PubMed", "id": "32416791", "url": "https://glygen.org/publication/PubMed/32416791" } ] }, { "annotation": "Plays a role as translation enhancer and involved in cell cycle regulation.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCTS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42", "locus": { "chromosome": "4", "start_pos": 16341132, "end_pos": 16350133, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012288", "url": "https://www.ensembl.org/id/ENSGALG00010012288" } ] } } ], "crossref": [ { "id": "Q5ZI42", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008517", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008517", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11609", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11609", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422363", "url": "https://www.ncbi.nlm.nih.gov/gene/422363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422363", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GVENIHY", "url": "https://omabrowser.org/oma/group/GVENIHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8Q8", "url": "https://www.orthodb.org/?gene=A0A8V0Y8Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDS9", "url": "https://www.orthodb.org/?gene=A0A8V0YDS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI42", "url": "https://www.orthodb.org/?gene=Q5ZI42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22798:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22798:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01472", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01472", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI42", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI42", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001099145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI42-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLIDQFPVIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGIFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTVVAIMAEGKQHALCVGVMKMSADDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181, "header": "sp|Q5ZI42-1|MCTS1_CHICK Isoform 1 of Malignant T-cell-amplified sequence 1 OS=Gallus gallus OX=9031 GN=MCTS1 PE=2 SV=1 CANONICAL=Q5ZI42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Q8/entry", "sequence": { "sequence": "MFLLGRFDEKENVSNCIQLKTSVIKGIKNQLIDQFPVIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGIFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTVVAIMAEGKQHALCVGVMKMSADDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 183, "header": "tr|A0A8V0Y8Q8-1|MCTS1_CHICK Computationally mapped isoform of Malignant T-cell-amplified sequence 1 OS=Gallus gallus OX=9031 GN=MCTS1 PE=2 SV=1 CANONICAL=Q5ZI42-1" }, "locus": { "chromosome": "4", "start_pos": 16348098, "end_pos": 16343054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029414.1", "url": "https://www.ensembl.org/id/ENSGALT00010029414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017085.1", "url": "https://www.ensembl.org/id/ENSGALP00010017085.1" } ] } }, { "isoform_ac": "A0A8V0YDS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDS9/entry", "sequence": { "sequence": "MSPCQWCAATGRGAAVANWNPASSIQTFDEKENVSNCIQLKTSVIKGIKNQLIDQFPVIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGIFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTVVAIMAEGKQHALCVGVMKMSADDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 204, "header": "tr|A0A8V0YDS9-1|MCTS1_CHICK Computationally mapped isoform of Malignant T-cell-amplified sequence 1 OS=Gallus gallus OX=9031 GN=MCTS1 PE=2 SV=1 CANONICAL=Q5ZI42-1" }, "locus": { "chromosome": "4", "start_pos": 16349334, "end_pos": 16343054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029420.1", "url": "https://www.ensembl.org/id/ENSGALT00010029420.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017090.1", "url": "https://www.ensembl.org/id/ENSGALP00010017090.1" } ] } }, { "isoform_ac": "Q5ZI42-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42/entry#Q5ZI42-1", "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLIDQFPVIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGIFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTVVAIMAEGKQHALCVGVMKMSADDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181, "header": "sp|Q5ZI42-1|MCTS1_CHICK Isoform 1 of Malignant T-cell-amplified sequence 1 OS=Gallus gallus OX=9031 GN=MCTS1 PE=2 SV=1 CANONICAL=Q5ZI42-1" }, "locus": { "chromosome": "4", "start_pos": 16348687, "end_pos": 16343054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029418.1", "url": "https://www.ensembl.org/id/ENSGALT00010029418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017088.1", "url": "https://www.ensembl.org/id/ENSGALP00010017088.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Altered expression of lactate dehydrogenase and monocarboxylate transporter involved in lactate metabolism in broiler wooden breast.", "journal": "Poultry science", "date": "2020-01", "authors": "Zhao Dan, Kogut Michael H, Genovese Kenneth J, Hsu Chuan-Yu, Lee Jason T, Farnell Yuhua Z", "evidence": [ { "database": "RefSeq", "id": "NP_001099145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099145" } ], "reference": [ { "type": "PubMed", "id": "32416791", "url": "https://glygen.org/publication/PubMed/32416791" } ] } ], "pathway": [ { "id": "gga:422363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJU5-1", "protein_name": "Malignant T-cell-amplified sequence", "gene_name": "LOC100738684", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPRQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAADTVVAIMAEGKQHALCVGVMKMSAEEIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7H1Q9-1", "protein_name": "Malignant T-cell-amplified sequence", "gene_name": "Mcts1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKGRFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 182 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P89886-1", "protein_name": "Translation machinery-associated protein 20", "gene_name": "TMA20", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFKKFTREDVHSRSKVKSSIQRTLKAKLVKQYPKIEDVIDELIPKKSQIELIKCEDKIQLYSVDGEVLFFQKFDELIPSLKLVHKFPEAYPTVQVDRGAIKFVLSGANIMCPGLTSAGADLPPAPGYEKGTIVVINAENKENALAIGELMMGTEEIKSVNKGHSIELIHHLGDPLWNFSVE", "length": 181 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KIE4-1", "protein_name": "Malignant T-cell-amplified sequence 1", "gene_name": "MCTS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86KL4-1", "protein_name": "Malignant T-cell-amplified sequence 1 homolog", "gene_name": "mcts1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFKKLSLKGSSNTNNQIKSSLQRNIKNSILAQYPKLKDIEEDVFPKKVPIVQVKCQNHINLVLINNEVLFFNEREGPYYPTLRFLHKYPNILPHVQVDKGAIKFVLQGANIMCRGLTSPGAKMEVDLPVDAIVAVMAEGKDHASAIGVMKMSTNDIRTINNDIGINNIHYLGDSLYMSPNLE", "length": 182 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB27-1", "protein_name": "Malignant T-cell-amplified sequence 1", "gene_name": "Mcts1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLLEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULC4-1", "protein_name": "Malignant T-cell-amplified sequence 1", "gene_name": "MCTS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK", "length": 181 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W445-1", "protein_name": "Malignant T-cell-amplified sequence 1 homolog", "gene_name": "MCTS1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKKFEEKDSISSIQQLKSSVQKGIRAKLLEAYPKLESHIDLILPKKDSYRIAKCHDHIELLLNGAGDQVFFRHRDGPWMPTLRLLHKFPYFVTMQQVDKGAIRFVLSGANVMCPGLTSPGACMTPADKDTVVAIMAEGKEHALAVGLLTLSTQEILAKNKGIGIETYHFLNDGLWKSKPVK", "length": 182 }, "evidence": [ { "id": "Q5ZI42", "url": "https://omabrowser.org/oma/group/Q5ZI42/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": "https://www.uniprot.org/uniprotkb/Q5ZI42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI42", "url": 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This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. On Nov 28, 2010 this sequence version replaced XP_001233978.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186160", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186160" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F409", "url": "https://www.uniprot.org/uniprotkb/Q5F409" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMIM15", "url": "https://www.uniprot.org/uniprotkb/Q5F409", "locus": { "chromosome": "Z", "start_pos": 19567111, "end_pos": 19571366, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012704", "url": "https://www.ensembl.org/id/ENSGALG00010012704" } ] } } ], "crossref": [ { "id": "Q5F409", "url": "https://alphafold.ebi.ac.uk/entry/Q5F409", "database": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR28644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28644:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28644:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F409", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F409", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001186160", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186160", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK1-1", "url": 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isoform of Small integral membrane protein 15 OS=Gallus gallus OX=9031 GN=SMIM15 PE=3 SV=1 CANONICAL=Q5F409-1" }, "locus": { "chromosome": "Z", "start_pos": 19571366, "end_pos": 19569963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030432.1", "url": "https://www.ensembl.org/id/ENSGALT00010030432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017651.1", "url": "https://www.ensembl.org/id/ENSGALP00010017651.1" } ] } }, { "isoform_ac": "Q5F409-1", "url": "https://www.uniprot.org/uniprotkb/Q5F409/entry#Q5F409-1", "sequence": { "sequence": "MFDVKAWAVYIVEWAAKDPYGFLTTVILVLTPLFIISAALSWKLAKMIETREREQKKKRKRQENIVKAKRAKKD", "length": 74, "header": "sp|Q5F409-1|SIM15_CHICK Isoform 1 of Small integral membrane protein 15 OS=Gallus gallus OX=9031 GN=SMIM15 PE=3 SV=1 CANONICAL=Q5F409-1" }, "locus": { "chromosome": "Z", "start_pos": 19570184, "end_pos": 19569963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030390.1", "url": "https://www.ensembl.org/id/ENSGALT00010030390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017626.1", "url": "https://www.ensembl.org/id/ENSGALP00010017626.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F409", "url": "https://www.uniprot.org/uniprotkb/Q5F409" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:770642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770642", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JWM3-1", "protein_name": "Small integral membrane protein 15", "gene_name": "Smim15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDVKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENISKYRCAKNT", "length": 74 }, "evidence": [ { "id": "Q5F409", "url": "https://omabrowser.org/oma/group/Q5F409/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BL25-1", "protein_name": "Small integral membrane protein 15", "gene_name": "SMIM15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD", "length": 74 }, "evidence": [ { "id": "Q5F409", "url": "https://omabrowser.org/oma/group/Q5F409/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A3KNM5-1", "protein_name": "Small integral membrane protein 15", "gene_name": "smim15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFIASALLSWKLAKMIEAKDREQKKKQKRQENIAKAKRAKKD", "length": 74 }, "evidence": [ { "id": "Q5F409", "url": "https://omabrowser.org/oma/group/Q5F409/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3MX14-1", "protein_name": "Small integral membrane protein 15", "gene_name": "LOC100850100", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFDLKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD", "length": 74 }, "evidence": [ { "id": "Q5F409", "url": "https://omabrowser.org/oma/group/Q5F409/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UTD9-1", "protein_name": "Small integral membrane protein 15", "gene_name": "Smim15", 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"Q5F409", "url": "https://www.uniprot.org/uniprotkb/Q5F409" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F409-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 74, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F409-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F409" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZKJ4-1", "uniprot_ac": "Q5ZKJ4", "uniprot_id": "FGOP2_CHICK", "mass": { "chemical_mass": 25198.0, "monoisotopic_mass": 25198.0 }, "refseq": { "ac": "NP_001007856", "name": "FGFR1 oncogene partner 2 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007856" }, "gene_names": [ { "name": "FGFR1OP2", "type": "recommended", "evidence": [ { "id": "Q5ZKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ] }, { "name": "FGFR1OP2", "type": "synonym", "evidence": [ { "id": "NP_001007856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007856" } ] }, { "name": "RCJMB04_10g7", "type": "synonym", "evidence": [ { "id": "Q5ZKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ] } ], "protein_names": [ { "name": "FGFR1 oncogene partner 2 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4/entry#names_and_taxonomy" } ] }, { "name": "FGFR1 oncogene partner 2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007856" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720090.1, HAEK01065694.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Dec 15, 2004 this sequence version replaced XP_416440.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007856" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGFR1OP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4", "locus": { "chromosome": "1", "start_pos": 68077262, "end_pos": 68065955, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014748", "url": "https://www.ensembl.org/id/ENSGALG00010014748" } ] } } ], "crossref": [ { "id": "Q5ZKJ4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014084", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418214", "url": "https://www.ncbi.nlm.nih.gov/gene/418214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418214", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418214", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYRQHTE", "url": "https://omabrowser.org/oma/group/KYRQHTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIA6", "url": "https://www.orthodb.org/?gene=A0A8V0YIA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPQ0", "url": "https://www.orthodb.org/?gene=A0A8V0YPQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKJ4", "url": "https://www.orthodb.org/?gene=Q5ZKJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12186:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12186:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKJ4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKJ4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKJ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMSCTIEKALADAKALVERLREHDNAAEALIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPSIIMKLKEQHSKELQVHVDQITEMAAVMRKAIEIDDKHGCKEQERIIQLEQENKGLREILQITRESFLNLKKEDASESTSLSGLVTSSDLSLRKS", "length": 217, "header": "sp|Q5ZKJ4-1|FGOP2_CHICK Isoform 1 of FGFR1 oncogene partner 2 homolog OS=Gallus gallus OX=9031 GN=FGFR1OP2 PE=2 SV=1 CANONICAL=Q5ZKJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA6/entry", "sequence": { "sequence": "MSCTIEKALADAKALVERLREHDNAAEALIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPSIIMKLKEQHSKELQVHVDQITEMAAVMRKAIEIDDKHGCKEQERIIQLEQENKGLREILQITRESFLNLKKEDASESTSLSGLVTSSDLSLRKS", "length": 215, "header": "tr|A0A8V0YIA6-1|FGOP2_CHICK Computationally mapped isoform of FGFR1 oncogene partner 2 homolog OS=Gallus gallus OX=9031 GN=FGFR1OP2 PE=2 SV=1 CANONICAL=Q5ZKJ4-1" }, "locus": { "chromosome": "1", "start_pos": 68074874, "end_pos": 68068464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035456.1", "url": "https://www.ensembl.org/id/ENSGALT00010035456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020629.1", "url": "https://www.ensembl.org/id/ENSGALP00010020629.1" } ] } }, { "isoform_ac": "A0A8V0YPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ0/entry", "sequence": { "sequence": "MICKEMSCTIEKALADAKALVERLREHDNAAEALIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPSIIMKLKEQHSKELQVHVDQITEMAAVMRKAIEIDDKHGCKEQERIIQLEQENKGLREILQITRESFLNLKKEDASESTSLSGLVTSSDLSLRKS", "length": 220, "header": "tr|A0A8V0YPQ0-1|FGOP2_CHICK Computationally mapped isoform of FGFR1 oncogene partner 2 homolog OS=Gallus gallus OX=9031 GN=FGFR1OP2 PE=2 SV=1 CANONICAL=Q5ZKJ4-1" }, "locus": { "chromosome": "1", "start_pos": 68074874, "end_pos": 68067416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035443.1", "url": "https://www.ensembl.org/id/ENSGALT00010035443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020625.1", "url": "https://www.ensembl.org/id/ENSGALP00010020625.1" } ] } }, { "isoform_ac": "Q5ZKJ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4/entry#Q5ZKJ4-1", "sequence": { "sequence": "MKMSCTIEKALADAKALVERLREHDNAAEALIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPSIIMKLKEQHSKELQVHVDQITEMAAVMRKAIEIDDKHGCKEQERIIQLEQENKGLREILQITRESFLNLKKEDASESTSLSGLVTSSDLSLRKS", "length": 217, "header": "sp|Q5ZKJ4-1|FGOP2_CHICK Isoform 1 of FGFR1 oncogene partner 2 homolog OS=Gallus gallus OX=9031 GN=FGFR1OP2 PE=2 SV=1 CANONICAL=Q5ZKJ4-1" }, "locus": { "chromosome": "1", "start_pos": 68074874, "end_pos": 68066021, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035451.1", "url": "https://www.ensembl.org/id/ENSGALT00010035451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020627.1", "url": "https://www.ensembl.org/id/ENSGALP00010020627.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418214", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418214", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VJ49-1", "protein_name": "FGFR1 onco partner 2", "gene_name": "FGFR1OP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERILQLEQENKGLREILQITRESFLNLRKDDVSESTSLSALVTNSDLSLRKS", "length": 215 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MD82-1", "protein_name": "FGFR1 oncogene partner 2 isoform X1", "gene_name": "Fgfr1op2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRSSREGVFLDASRRILEAPQHGLERRHLEANQNELQAHADQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS", "length": 253 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BBF9-1", "protein_name": "FGFR1 onco partner 2", "gene_name": "FGFR1OP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHTKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKEDVSESTSLSALVTSSDLSLRKS", "length": 215 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6TA25-1", "protein_name": "FGFR1 oncogene partner 2 homolog", "gene_name": "Fgfr1op2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNSCEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS", "length": 253 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T338-1", "protein_name": "FGFR1 oncogene partner 2 homolog", "gene_name": "fgfr1op2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTCTLEKVLADAKSLVERLRDHDSAAEILIEQTTLLNKRVEAMKQYQEEIEVLNQVARHRPRSTLVMGIQQENRQIRELQQENKELHTSLEEHQSALELIMSKYREQVFRLLMASKKEDPTIVTQLREQHTNEMQAHIEKINEMATVMRKAIEVDEGRLCEDEERIKRLELENSGLRELLGISREAFLLLKRDDTSDSTSLSPLLTSTDISLRKS", "length": 215 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CRA9-1", "protein_name": "FGFR1 oncogene partner 2 homolog", "gene_name": "Fgfr1op2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNSCEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS", "length": 253 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVK5-1", "protein_name": "FGFR1 oncogene partner 2", "gene_name": "FGFR1OP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS", "length": 253 }, "evidence": [ { "id": "Q5ZKJ4", "url": "https://omabrowser.org/oma/group/Q5ZKJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKJ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 217, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKJ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKJ4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJL8-1", "uniprot_ac": "Q5ZJL8", "uniprot_id": "ABHDD_CHICK", "mass": { "chemical_mass": 38360.0, "monoisotopic_mass": 38360.0 }, "refseq": { "ac": "NP_001008681", "name": "protein ABHD13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" }, "gene_names": [ { "name": "ABHD13", "type": "recommended", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ] }, { "name": "ABHD13", "type": "synonym", "evidence": [ { "id": "NP_001008681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" } ] }, { "name": "RCJMB04_17d11", "type": "synonym", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ] } ], "protein_names": [ { "name": "Protein ABHD13", "type": "recommended", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8/entry#names_and_taxonomy" } ] }, { "name": "3.-.-.-", "type": "synonym", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8/entry#names_and_taxonomy" } ] }, { "name": "Abhydrolase domain-containing protein 13", "type": "synonym", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8/entry#names_and_taxonomy" } ] }, { "name": "Alpha/beta hydrolase domain-containing protein 13", "type": "synonym", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8/entry#names_and_taxonomy" } ] }, { "name": "abhydrolase domain-containing protein 13", "type": "synonym", "evidence": [ { "id": "NP_001008681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" } ] }, { "name": "alpha/beta hydrolase domain-containing protein 13", "type": "synonym", "evidence": [ { "id": "NP_001008681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" } ] }, { "name": "protein ABHD13", "type": "synonym", "evidence": [ { "id": "NP_001008681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.99579.1, HAEK01045430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000025.1. On or before Dec 11, 2020 this sequence version replaced XP_015129648.1, XP_416959.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABHD13", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8", "locus": { "chromosome": "1", "start_pos": 140227563, "end_pos": 140242826, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014965", "url": "https://www.ensembl.org/id/ENSGALG00010014965" } ] } } ], "crossref": [ { "id": "Q5ZJL8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016853", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016853", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418763", "url": "https://www.ncbi.nlm.nih.gov/gene/418763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418763", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYWTSED", "url": "https://omabrowser.org/oma/group/QYWTSED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ03", "url": "https://www.orthodb.org/?gene=A0A8V0YJ03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJL8", "url": "https://www.orthodb.org/?gene=Q5ZJL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJL8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJL8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008681", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJL8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKSRMLWTFVERWLLALASWSWGLCRISLLPLIVTFHLYGGIILLLLIFVSIAGILYKFQDMLLYFPEQPSSSRLYVPMPTGIPHENIFIKTKDGVLLNLILLRYTGDNAAYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLILVDYRGYGKSEGEASEEGLYIDSEAVLDYVMTRSDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPARTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSSEEMAKTSSNVTII", "length": 337, "header": "sp|Q5ZJL8-1|ABHDD_CHICK Isoform 1 of Protein ABHD13 OS=Gallus gallus OX=9031 GN=ABHD13 PE=2 SV=1 CANONICAL=Q5ZJL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ03/entry", "sequence": { "sequence": "MGFTWSRRSLTTTMEKSRMLWTFVERWLLALASWSWGLCRISLLPLIVTFHLYGGIILLLLIFVSIAGILYKFQDMLLYFPEQPSSSRLYVPMPTGIPHENIFIKTKDGVLLNLILLRYTGDNAAYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLILVDYRGYGKSEGEASEEGLYIDSEAVLDYVMTRSDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPARTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSSEEMAKTSSNVTII", "length": 350, "header": "tr|A0A8V0YJ03-1|ABHDD_CHICK Computationally mapped isoform of Protein ABHD13 OS=Gallus gallus OX=9031 GN=ABHD13 PE=2 SV=1 CANONICAL=Q5ZJL8-1" }, "locus": { "chromosome": "1", "start_pos": 140233462, "end_pos": 140232087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035995.1", "url": "https://www.ensembl.org/id/ENSGALT00010035995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020892.1", "url": "https://www.ensembl.org/id/ENSGALP00010020892.1" } ] } }, { "isoform_ac": "Q5ZJL8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8/entry#Q5ZJL8-1", "sequence": { "sequence": "MEKSRMLWTFVERWLLALASWSWGLCRISLLPLIVTFHLYGGIILLLLIFVSIAGILYKFQDMLLYFPEQPSSSRLYVPMPTGIPHENIFIKTKDGVLLNLILLRYTGDNAAYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLILVDYRGYGKSEGEASEEGLYIDSEAVLDYVMTRSDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPARTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSSEEMAKTSSNVTII", "length": 337, "header": "sp|Q5ZJL8-1|ABHDD_CHICK Isoform 1 of Protein ABHD13 OS=Gallus gallus OX=9031 GN=ABHD13 PE=2 SV=1 CANONICAL=Q5ZJL8-1" }, "locus": { "chromosome": "1", "start_pos": 140233097, "end_pos": 140232087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035996.1", "url": "https://www.ensembl.org/id/ENSGALT00010035996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020893.1", "url": "https://www.ensembl.org/id/ENSGALP00010020893.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1B6-1", "protein_name": "Protein ABHD13", "gene_name": "Abhd13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKPWMLWSFIERWLLALVSWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII", "length": 337 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GTP1-1", "protein_name": "Protein ABHD13", "gene_name": "Abhd13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKSWMLWSFIERWLLALASWSWALCRISLLPLIVTFHLYGGIILLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGVRLNLILVRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII", "length": 337 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P42840-1", "protein_name": "Uncharacterized membrane protein YNL320W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLWKVSKMFLGGLVALTTISVATLYHYQNRLVYPSWAQGARNHVDTPDSRGIPYEKLTLITQDHIKLEAWDIKNENSTSTVLILCPNAGNIGYFILIIDIFYRQFGMSVFIYSYRGYGNSEGSPSEKGLKLDADCVISHLSTDSFHSKRKLVLYGRSLGGANALYIASKFRDLCDGVILENTFLSIRKVIPYIFPLLKRFTLLCHEIWNSEGLMGSCSSETPFLFLSGLKDEIVPPFHMRKLYETCPSSNKKIFEFPLGSHNDTIIQDGYWDIIRDFLIEKGFI", "length": 284 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q32LS6-1", "protein_name": "Protein ABHD13", "gene_name": "abhd13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKPWRLWGPLEACLLSVCAWSWGFCRVSLLALILTFHLYGGFVLLGLILASLAGILYKFQDVLLYFPDQPSSSRLYVPMPTGIPHENVYIRTKDGIRLNLILLRYTGENPAGAPTILYFHGNAGNIGHRVPNALLMLVNLKANVVLVDYRGYGKSEGDPSEDGLYQDAEATLDYVMTRPDIDKTKVVLFGRSLGGAVAIRLASCNPHRVAAIMVENTFLSIPHMAATLFSFFPMRYLPLWCYKNKFLSYRHVVPCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPEGTHNDTWQCQGYFSALEQFMKELLKSHAREETTQGTASVTII", "length": 337 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54H73-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYSTLISTAYWGSIIAATGLICIASIIYASQEKLLYIPDRNIVLHPSQFGLEDNFEEIFLTTSDGIKIQTWFFRQENSKSVPTLLFCHSNAGNLSHRLDNIRHLFENVRCNVLILSYRGYGKSQGSPTEIGLKKDIDACMEYLLNDPTIDPNTIMCFGRSLGGAVAIDTAYRYPNNIKALILENTFASVPDMVDAVLPMLKLFKPFCRSRWDSKETIKHITCDILFLSAKNDELVPASHMKLLEKHAHQCKKKTIVFENGRHMDLMFQHNYYKYIKEFMLEKFGDYI", "length": 287 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7L211-1", "protein_name": "Protein ABHD13", "gene_name": "ABHD13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGIILLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGIRLNLILIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNVTII", "length": 337 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80UX8-1", "protein_name": "Protein ABHD13", "gene_name": "Abhd13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKSWMLWSFIERWLLALASWSWALCRISLLPLIVTFHLYGGIVLLLLIFVSIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGVRLNLILVRYTGDNSPYCPTIIYFHGNAGNIGHRLPNALLMLVNLRVNLVLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKVFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVIKSHSPEDMTKTSSNVTII", "length": 337 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RXP6-1", "protein_name": "Alpha/beta hydrolase domain-containing protein WAV2", "gene_name": "WAV2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVTYVSALFYGFGGIVVAGVALLVAFQEKLVYVPVLPGLSKSYPITPARLNLIYEDIWLQSSDGVRLHAWFIKMFPECRGPTILFFQENAGNIAHRLEMVRIMIQKLKCNVFMLSYRGYGASEGYPSQQGIIKDAQAALDHLSGRTDIDTSRIVVFGRSLGGAVGAVLTKNNPDKVSALILENTFTSILDMAGVLLPFLKWFIGGSGTKSLKLLNFVVRSPWKTIDAIAEIKQPVLFLSGLQDEMVPPFHMKMLYAKAAARNPQCTFVEFPSGMHMDTWLSGGEVYWKTNLQFLEKYAPEKRKEDTGR", "length": 308 }, "evidence": [ { "id": "Q5ZJL8", "url": "https://omabrowser.org/oma/group/Q5ZJL8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJL8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJL8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJL8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJL8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJL8" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000255", "start_pos": 115, "end_pos": 222, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 299 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 }, { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLN7-1", "uniprot_ac": "Q5ZLN7", "uniprot_id": "PBIR1_CHICK", "mass": { "chemical_mass": 30523.0, "monoisotopic_mass": 30523.0 }, "refseq": { "ac": "NP_001026289", "name": "uncharacterized protein LOC422237", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" }, "gene_names": [ { "name": "PABIR1", "type": "recommended", "evidence": [ { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ] }, { "name": "PABIR3", "type": "recommended", "evidence": [ { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ] }, { "name": "FAM122A", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" }, { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ] }, { "name": "FAM122C", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "PABIR1", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "PABIR3", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "RCJMB04_5g5", "type": "synonym", "evidence": [ { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ] } ], "protein_names": [ { "name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "type": "recommended", "evidence": [ { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7/entry#names_and_taxonomy" } ] }, { "name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "PABIR family member 1", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" }, { "id": "Q5ZLN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7/entry#names_and_taxonomy" } ] }, { "name": "PABIR family member 3", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "family with sequence similarity 122C", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "protein FAM122A", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "protein FAM122C", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "name": "uncharacterized protein LOC422237", "type": "synonym", "evidence": [ { "id": "NP_001026289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719697.1, HAEK01029299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Aug 8, 2005 this sequence version replaced XP_420225.1. Sequence Note: This sequence has been modified as follows: removed 27 bp suspected to be vector contamination from the 3' end.", "evidence": [ { "database": "RefSeq", "id": "NP_001026289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289" } ] }, { "annotation": "Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin-mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7#function" }, { "database": "UniProtKB", "id": "Q96E09", "url": "https://www.uniprot.org/uniprotkb/Q96E09#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PABIR1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7", "locus": {} } ], "crossref": [ { "id": "Q5ZLN7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006127", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006127", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422237", "url": "https://www.ncbi.nlm.nih.gov/gene/422237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422237", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISHHTDS", "url": "https://omabrowser.org/oma/group/ISHHTDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLN7", "url": "https://www.orthodb.org/?gene=Q5ZLN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22227:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22227:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLN7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLN7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLN7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDNSQVFQGSVLRTRRNSTTVMNRHSLFVPSSPIRIPSSRLHQIKQEEGMNLMNRETVHEREVQVAMQMSQSWEESLSLSNNDFEKSSSPKQVDFVPVSPAPSPTRGIGKQCFSPSLQSLVSSSGLPPSPSPSPTRRFSSRRSQSPINCIRPSVLGPIKRKGVTEMEDHPKRLFQGSTNMLSSEALHQPDLGGCLSAHTLDDNRSSAGSSCDSPAEAGASTGSPVSLSDSRSPFLPVDLTAKLPID", "length": 284, "header": "sp|Q5ZLN7-1|PBIR1_CHICK Isoform 1 of P2R1A-PPP2R2A-interacting phosphatase regulator 1 OS=Gallus gallus OX=9031 GN=PABIR1 PE=2 SV=1 CANONICAL=Q5ZLN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT8/entry", "sequence": { "sequence": "MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDNSQVFQGSVLRTRRNSTTVMNRHSLEEGMNLMNRETVHEREVQVAMQMSQSWEESLSLSNNDFEKSSSPKQVDFVPVSPAPSPTRGIGKQCFSPSLQSLVSSSGLPPSPSPSPTRRFSSRRSQSPINCIRPSVLGPIKRKGVTEMEDHPKRLFQGSTNMLSSEALHQPDLGGCLSAHTLDDNRSSAGSSCDSPAEAGASTGSPVSLSDSRSPFLPVDLTAKLPID", "length": 265, "header": "tr|A0A8V0YLT8-1|PBIR1_CHICK Computationally mapped isoform of P2R1A-PPP2R2A-interacting phosphatase regulator 1 OS=Gallus gallus OX=9031 GN=PABIR1 PE=2 SV=1 CANONICAL=Q5ZLN7-1" }, "locus": { "chromosome": "4", "start_pos": 4048665, "end_pos": 4037278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037988.1", "url": "https://www.ensembl.org/id/ENSGALT00010037988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021916.1", "url": "https://www.ensembl.org/id/ENSGALP00010021916.1" } ] } }, { "isoform_ac": "Q5ZLN7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7/entry#Q5ZLN7-1", "sequence": { "sequence": "MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDNSQVFQGSVLRTRRNSTTVMNRHSLFVPSSPIRIPSSRLHQIKQEEGMNLMNRETVHEREVQVAMQMSQSWEESLSLSNNDFEKSSSPKQVDFVPVSPAPSPTRGIGKQCFSPSLQSLVSSSGLPPSPSPSPTRRFSSRRSQSPINCIRPSVLGPIKRKGVTEMEDHPKRLFQGSTNMLSSEALHQPDLGGCLSAHTLDDNRSSAGSSCDSPAEAGASTGSPVSLSDSRSPFLPVDLTAKLPID", "length": 284, "header": "sp|Q5ZLN7-1|PBIR1_CHICK Isoform 1 of P2R1A-PPP2R2A-interacting phosphatase regulator 1 OS=Gallus gallus OX=9031 GN=PABIR1 PE=2 SV=1 CANONICAL=Q5ZLN7-1" }, "locus": { "chromosome": "4", "start_pos": 4048665, "end_pos": 4037278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037987.1", "url": "https://www.ensembl.org/id/ENSGALT00010037987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021915.1", "url": "https://www.ensembl.org/id/ENSGALP00010021915.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422237", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYT4-1", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEKMELDLELPAGTGASPAEGGGPGSGGLRRSNSAPLIHGLSDSSPVFQAEAPSARRNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEESFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFSPSLQSFVSSNGLPPSPIPSPTTRFTTRRSQSPINCIRPSVLGPLKRKCEMETDYQPKRFFQGITNMLSSDVAQLSEPGVCVSSDTLDGNSSSAGSSCNSPAKVSTTTDSPVSPAQAASPFIPVDELSSK", "length": 286 }, "evidence": [ { "id": "Q5ZLN7", "url": "https://omabrowser.org/oma/group/Q5ZLN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96E09-1", "protein_name": "PPP2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "PABIR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQEKMELDLELPPGTGGSPAEGGGSGGGGGLRRSNSAPLIHGLSDTSPVFQAEAPSARRNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEESFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFSPSLQSFVSSNGLPPSPIPSPTTRFTTRRSQSPINCIRPSVLGPLKRKCEMETEYQPKRFFQGITNMLSSDVAQLSDPGVCVSSDTLDGNSSSAGSSCNSPAKVSTTTDSPVSPAQAASPFIPLDELSSK", "length": 287 }, "evidence": [ { "id": "Q5ZLN7", "url": "https://omabrowser.org/oma/group/Q5ZLN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB52-1", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEKMELDLELPAGASPAEGGGPGGGGLRRSNSAPLIHGLSDSSPVFQAEAPSARRNSTTFPSRHGLLLPASPVRMHSSRLHQIKQEEGMDLINRETVHEREVQTAMQISHSWEESFSLSDNDVEKSASPKRIDFIPVSPAPSPTRGIGKQCFSPSLQSFVSSNGLPPSPIPSPTTRFTTRRSQSPINCIRPSVLGPLKRKCEMETDYQPKRFFQGITNMLSSDVAQLSDPGVCVSSDTLDGNSSSAGSSCNSPAKVSTTTDSPVSPAQAASPFIPVDELSSK", "length": 284 }, "evidence": [ { "id": "Q5ZLN7", "url": "https://omabrowser.org/oma/group/Q5ZLN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" }, { "name": "mitotic G2/M transition checkpoint", "id": "GO:0044818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044818", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLN7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLN7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLN7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 143 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZKU1-1", "uniprot_ac": "Q5ZKU1", "uniprot_id": "DCNL1_CHICK", "mass": { "chemical_mass": 30109.0, "monoisotopic_mass": 30109.0 }, "refseq": { "ac": "NP_001026489", "name": "DCN1-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" }, "gene_names": [ { "name": "DCUN1D1", "type": "recommended", "evidence": [ { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1" } ] }, { "name": "DCUN1D1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" } ] }, { "name": "DCUN1L1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" }, { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1" } ] }, { "name": "RCJMB04_9c8", "type": "synonym", "evidence": [ { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1" } ] } ], "protein_names": [ { "name": "DCN1-like protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1/entry#names_and_taxonomy" } ] }, { "name": "DCN1, defective in cullin neddylation 1, domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" } ] }, { "name": "DCN1-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" } ] }, { "name": "DCUN1 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" }, { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1/entry#names_and_taxonomy" } ] }, { "name": "Defective in cullin neddylation protein 1-like protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZKU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1/entry#names_and_taxonomy" } ] }, { "name": "defective in cullin neddylation protein 1-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719993.1, HAEK01045182.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ719993.1. On Aug 8, 2005 this sequence version replaced XP_422772.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489" } ] }, { "annotation": "Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1#function" }, { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCUN1D1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1", "locus": { "chromosome": "9", "start_pos": 16182632, "end_pos": 16112922, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016529", "url": "https://www.ensembl.org/id/ENSGALG00010016529" } ] } } ], "crossref": [ { "id": "Q5ZKU1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008807", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008807", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424963", "url": "https://www.ncbi.nlm.nih.gov/gene/424963", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424963", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424963", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHEPDKM", "url": "https://omabrowser.org/oma/group/PHEPDKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPV5", "url": "https://www.orthodb.org/?gene=A0A8V0YPV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWM6", "url": "https://www.orthodb.org/?gene=A0A8V0YWM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY81", "url": "https://www.orthodb.org/?gene=A0A8V0YY81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKU1", "url": "https://www.orthodb.org/?gene=Q5ZKU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKU1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKU1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKU1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKLKSSQKDKVRQFMVFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV", "length": 259, "header": "sp|Q5ZKU1-1|DCNL1_CHICK Isoform 1 of DCN1-like protein 1 OS=Gallus gallus OX=9031 GN=DCUN1D1 PE=2 SV=1 CANONICAL=Q5ZKU1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV5/entry", "sequence": { "sequence": "MNKLKSSQKDKVRQFMVFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSII", "length": 258, "header": "tr|A0A8V0YPV5-1|DCNL1_CHICK Computationally mapped isoform of DCN1-like protein 1 OS=Gallus gallus OX=9031 GN=DCUN1D1 PE=2 SV=1 CANONICAL=Q5ZKU1-1" }, "locus": { "chromosome": "9", "start_pos": 16128119, "end_pos": 16113120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039822.1", "url": "https://www.ensembl.org/id/ENSGALT00010039822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023042.1", "url": "https://www.ensembl.org/id/ENSGALP00010023042.1" } ] } }, { "isoform_ac": "A0A8V0YWM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM6/entry", "sequence": { "sequence": "MNKLKSSQKDKVRQFMVFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGKNFHFLSLTSNCVMLHLLLCVCFGTAAELEDQW", "length": 267, "header": "tr|A0A8V0YWM6-1|DCNL1_CHICK Computationally mapped isoform of DCN1-like protein 1 OS=Gallus gallus OX=9031 GN=DCUN1D1 PE=2 SV=1 CANONICAL=Q5ZKU1-1" }, "locus": { "chromosome": "9", "start_pos": 16126138, "end_pos": 16113120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039809.1", "url": "https://www.ensembl.org/id/ENSGALT00010039809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023031.1", "url": "https://www.ensembl.org/id/ENSGALP00010023031.1" } ] } }, { "isoform_ac": "A0A8V0YY81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY81/entry", "sequence": { "sequence": "MQLELQTGRCCGVSAVPEDLSFSHRLCPKVRVGKRSRALQCHKECSPMNKLKSSQKDKVRQFMVFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV", "length": 306, "header": "tr|A0A8V0YY81-1|DCNL1_CHICK Computationally mapped isoform of DCN1-like protein 1 OS=Gallus gallus OX=9031 GN=DCUN1D1 PE=2 SV=1 CANONICAL=Q5ZKU1-1" }, "locus": { "chromosome": "9", "start_pos": 16127545, "end_pos": 16119233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039826.1", "url": "https://www.ensembl.org/id/ENSGALT00010039826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023045.1", "url": "https://www.ensembl.org/id/ENSGALP00010023045.1" } ] } }, { "isoform_ac": "Q5ZKU1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1/entry#Q5ZKU1-1", "sequence": { "sequence": "MNKLKSSQKDKVRQFMVFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASITVLIIAWKFRAATQCEFSKLEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV", "length": 259, "header": "sp|Q5ZKU1-1|DCNL1_CHICK Isoform 1 of DCN1-like protein 1 OS=Gallus gallus OX=9031 GN=DCUN1D1 PE=2 SV=1 CANONICAL=Q5ZKU1-1" }, "locus": { "chromosome": "9", "start_pos": 16127545, "end_pos": 16113120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039837.1", "url": "https://www.ensembl.org/id/ENSGALT00010039837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023054.1", "url": "https://www.ensembl.org/id/ENSGALP00010023054.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424963", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1Y7VP24-1", "protein_name": "DCN1-like protein", "gene_name": "Tes3-ps", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKLKSSQKDKVSQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYTRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQFEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSSMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTL", "length": 259 }, "evidence": [ { "id": "Q5ZKU1", "url": "https://omabrowser.org/oma/group/Q5ZKU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6AI94-1", "protein_name": "DCN1-like protein", "gene_name": "Dcun1d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSVEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSSMIADDMSNYDEEGAWPVLIDDFVEFARPQISGTKSTTV", "length": 259 }, "evidence": [ { "id": "Q5ZKU1", "url": "https://omabrowser.org/oma/group/Q5ZKU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96GG9-1", "protein_name": "DCN1-like protein 1", "gene_name": "DCUN1D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV", "length": 259 }, "evidence": [ { "id": "Q5ZKU1", "url": "https://omabrowser.org/oma/group/Q5ZKU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZ73-1", "protein_name": "DCN1-like protein 1", "gene_name": "Dcun1d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F413-1", "uniprot_ac": "Q5F413", "uniprot_id": "SMAP2_CHICK", "mass": { "chemical_mass": 46315.0, "monoisotopic_mass": 46315.0 }, "refseq": { "ac": "NP_001026073", "name": "stromal membrane-associated protein 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" }, "gene_names": [ { "name": "SMAP2", "type": "recommended", "evidence": [ { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ] }, { "name": "RCJMB04_3n15", "type": "synonym", "evidence": [ { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ] }, { "name": "SMAP1L", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" }, { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ] }, { "name": "SMAP2", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] } ], "protein_names": [ { "name": "Stromal membrane-associated protein 2", "type": "recommended", "evidence": [ { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413/entry#names_and_taxonomy" } ] }, { "name": "Stromal membrane-associated protein 1-like", "type": "synonym", "evidence": [ { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413/entry#names_and_taxonomy" } ] }, { "name": "stromal membrane-associated GTPase-activating protein 2", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] }, { "name": "stromal membrane-associated protein 1-like", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] }, { "name": "stromal membrane-associated protein 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] }, { "name": "stromal membrane-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001026073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851487.1, HAEK01020902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Aug 8, 2005 this sequence version replaced XP_417789.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073" } ] }, { "annotation": "GTPase activating protein. May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMAP2", "url": "https://www.uniprot.org/uniprotkb/Q5F413", "locus": { "chromosome": "23", "start_pos": 5258830, "end_pos": 5245442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017167", "url": "https://www.ensembl.org/id/ENSGALG00010017167" } ] } } ], "crossref": [ { "id": "Q5F413", "url": "https://alphafold.ebi.ac.uk/entry/Q5F413", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029244", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029244", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08859", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08859", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419641", "url": "https://www.ncbi.nlm.nih.gov/gene/419641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419641", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMGYGQS", "url": "https://omabrowser.org/oma/group/MMGYGQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT89", "url": "https://www.orthodb.org/?gene=A0A8V0YT89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5F413", "url": "https://www.orthodb.org/?gene=Q5F413", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45705:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45705:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F413", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F413", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YT89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F413-1", "url": "https://www.uniprot.org/uniprotkb/Q5F413-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKSVRDVERYQAVLGSLLSEEENKYCADCQAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAFLPENFRRPQTDQAVEGFIRDKYEKKKYMDRSIDINTFRKEKDDKWKKSNEPVSERKLEPIVFEKVKMPQKKEETQQSRKSSPKSTEPVIDLLGLDAPVPSTLTNGRPCSLEKDLDLFASVGLNSDSRKVSGSMPTSGSAGSVPENLNLFPEPGGKGEEAGKKQLSKDSILSLYGSQTPQLPAQGAMFMAPAQMAYPAAAYTSFPGVPPSSSMMGGMMAPSVGVMAQHGAAGMVTPMAIPAGYVGNVQAAVIGVPNGMMAAQQAGYVAGMAAVPQPVYGVQPAQQLQWNITQMTQQMAGMNFYGANGVMGYGQSMGGGGAQGSNQSLSTQLWK", "length": 428, "header": "sp|Q5F413-1|SMAP2_CHICK Isoform 1 of Stromal membrane-associated protein 2 OS=Gallus gallus OX=9031 GN=SMAP2 PE=2 SV=1 CANONICAL=Q5F413-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YT89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT89/entry", "sequence": { "sequence": "MLLPLCVAKLLLMLTVGAEGDVTKREQTGVFSRAALSTLRIPVALLRSTESWHSMGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAFLPENFRRPQTDQAVEGFIRDKYEKKKYMDRSIDINTFRKEKDDKWKKSNEPVSERKLEPIVFEKVKMPQKKEETQQSRKSSPKSTEPVIDLLGLDAPVPSTLTNGRPCSLEKDLDLFASVGLNSDSRKVSGSMPTSGSAGSVPENLNLFPEPGGKGEEAGKKQLSKDSILSLYGSQTPQLPAQGAMFMAPAQMAYPAAAYTSFPGVPPSSSMMGGMMAPSVGVMAQHGAAGMVTPMAIPAGYVGNVQAAVIGVPNGMMAAQQAGYVAGMAAVPQPVYGVQPAQQLQWNITQMTQQMAGMNFYGANGVMGYGQSMGGGGAQGSNQSLSTQLWK", "length": 449, "header": "tr|A0A8V0YT89-1|SMAP2_CHICK Computationally mapped isoform of Stromal membrane-associated protein 2 OS=Gallus gallus OX=9031 GN=SMAP2 PE=2 SV=1 CANONICAL=Q5F413-1" }, "locus": { "chromosome": "23", "start_pos": 5256978, "end_pos": 5247259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041415.1", "url": "https://www.ensembl.org/id/ENSGALT00010041415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024261.1", "url": "https://www.ensembl.org/id/ENSGALP00010024261.1" } ] } }, { "isoform_ac": "Q5F413-1", "url": "https://www.uniprot.org/uniprotkb/Q5F413/entry#Q5F413-1", "sequence": { "sequence": "MTGKSVRDVERYQAVLGSLLSEEENKYCADCQAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAFLPENFRRPQTDQAVEGFIRDKYEKKKYMDRSIDINTFRKEKDDKWKKSNEPVSERKLEPIVFEKVKMPQKKEETQQSRKSSPKSTEPVIDLLGLDAPVPSTLTNGRPCSLEKDLDLFASVGLNSDSRKVSGSMPTSGSAGSVPENLNLFPEPGGKGEEAGKKQLSKDSILSLYGSQTPQLPAQGAMFMAPAQMAYPAAAYTSFPGVPPSSSMMGGMMAPSVGVMAQHGAAGMVTPMAIPAGYVGNVQAAVIGVPNGMMAAQQAGYVAGMAAVPQPVYGVQPAQQLQWNITQMTQQMAGMNFYGANGVMGYGQSMGGGGAQGSNQSLSTQLWK", "length": 428, "header": "sp|Q5F413-1|SMAP2_CHICK Isoform 1 of Stromal membrane-associated protein 2 OS=Gallus gallus OX=9031 GN=SMAP2 PE=2 SV=1 CANONICAL=Q5F413-1" }, "locus": { "chromosome": "23", "start_pos": 5256978, "end_pos": 5245487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041419.1", "url": "https://www.ensembl.org/id/ENSGALT00010041419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024262.1", "url": "https://www.ensembl.org/id/ENSGALP00010024262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419641", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XM71-1", "protein_name": "Small ArfGAP2", "gene_name": "Smap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPFFDSSLISVCRAVEGFIRDKYEKKKYMDRSLDINVLRKEKDDKWKRGSEPAPEKKMEPVVFEKVKMPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKTSNALEKDLDLLASVPSPSSVSRKAVGSMPTAGSAGSVPENLNLFPEPGSKSEETGKKQLSKDSILSLYGSQTPQMPAQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAHPGASGMVTPMAMPAGYMGGMQASMAGVPSGMMTTQQAGYMASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMSYGQSMGGGNGQAANQTLSPQMWK", "length": 439 }, "evidence": [ { "id": "Q5F413", "url": "https://omabrowser.org/oma/group/Q5F413/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EA00-1", "protein_name": "Stromal membrane-associated protein 2", "gene_name": "SMAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDHAVEGFIRDKYEKKKYMDRSLDINAFRKEKDNKWKRGSEPAPEKKMEPVVFEKVKMPQKKEDPQLPRKTSPKSKAPVVDLLGLDAPVSCSIANGKTSNTLEKDLDLLASVSSPSSSVSRKVVGSMPTPGSAGSVPENLNLFPEPGSKSEETSKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSLMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQASYMAGMAAMPQTMYGVQPAQQLQWNLTQMTQQMAGMNFCGTNGMLSYGQSMNGGNGQAANQTLSPQMWK", "length": 429 }, "evidence": [ { "id": "Q5F413", "url": "https://omabrowser.org/oma/group/Q5F413/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TN29-1", "protein_name": "Stromal membrane-associated protein 2", "gene_name": "Smap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINVLRKEKDDKWKRGNEPAPEKKMEPVVFEKVKMPQKKEDAQLPRKSSPKSAAPVMDLLGLDAPVACSIANSKTSNALEKDLDLLASVPSPSSVSRKAVGSMPTAGSAGSVPENLNLFPEPGSKSEETGKKQLSKDSILSLYGSQTPQMPAQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGGMVPPPVGMVAQPGASGMLTPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMASMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMGGGNGQAANQTLSPQMWK", "length": 428 }, "evidence": [ { "id": "Q5F413", "url": "https://omabrowser.org/oma/group/Q5F413/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WU79-1", "protein_name": "Stromal membrane-associated protein 2", "gene_name": "SMAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK", "length": 429 }, "evidence": [ { "id": "Q5F413", "url": "https://omabrowser.org/oma/group/Q5F413/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5F413", "url": "https://www.uniprot.org/uniprotkb/Q5F413" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F413-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 428, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F413-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F413" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F413" }, { "id": "PRU00288", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00288" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000255", "start_pos": 13, "end_pos": 139, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 384, "end_pos": 386 }, { "start_pos": 419, "end_pos": 421 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZK21-1", "uniprot_ac": "Q5ZK21", "uniprot_id": "INT14_CHICK", "mass": { "chemical_mass": 57533.0, "monoisotopic_mass": 57533.0 }, "refseq": { "ac": "NP_001005825", "name": "integrator complex subunit 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" }, "gene_names": [ { "name": "INTS14", "type": "recommended", "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ] }, { "name": "VWA9", "type": "recommended", "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ] }, { "name": "C10H15ORF44", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "name": "C15orf44", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "name": "INTS14", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "name": "RCJMB04_13l3", "type": "synonym", "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ] }, { "name": "VWA9", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" }, { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 14", "type": "recommended", "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21/entry#names_and_taxonomy" } ] }, { "name": "UPF0464 protein C15orf44 homolog", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "name": "integrator complex subunit 14", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "name": "von Willebrand factor A domain-containing protein 9", "type": "synonym", "evidence": [ { "id": "NP_001005825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" }, { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720263.1, HAEK01031739.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000246.1. On Jan 13, 2005 this sequence version replaced XP_413909.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001005825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825" } ] }, { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs). Within the integrator complex, INTS14 is part of the integrator tail module that acts as a platform for the recruitment of transcription factors at promoters.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21#function" }, { "database": "UniProtKB", "id": "Q96SY0", "url": "https://www.uniprot.org/uniprotkb/Q96SY0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS14", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21", "locus": {} } ], "crossref": [ { "id": "Q5ZK21", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZK21", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007491", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415540", "url": "https://www.ncbi.nlm.nih.gov/gene/415540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415540", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSSVVWI", "url": "https://omabrowser.org/oma/group/QSSVVWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWU1", "url": "https://www.orthodb.org/?gene=A0A8V0YWU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZK21", "url": "https://www.orthodb.org/?gene=Q5ZK21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13532:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13532:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZK21", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZK21", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001005825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YWU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK21-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAVHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALLGVCNIVQQEWGAAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTSDVQVFPRPEPFIIDEEIDPIPKAINTDLEIVGFVDIADISSPPVLSRHLVLPIALNREGDEVGPGITDDTEDENSANQIAGKIPNFCVLLHGSLKVEGMVAVVQLGPEWYGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGDDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKVASTGASEYTAYDHNIAPLQTDFPTTSTERM", "length": 518, "header": "sp|Q5ZK21-1|INT14_CHICK Isoform 1 of Integrator complex subunit 14 OS=Gallus gallus OX=9031 GN=INTS14 PE=2 SV=1 CANONICAL=Q5ZK21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWU1/entry", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAVHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALLGVCNIVQQEWGAAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTSDVQVFPRPEPFIIDEEIDPIPKAINTDLEIVGFVDIADISSPPVLSRHLVLPIALNRGDEVGPGITDDTEDENSANQIAGKIPNFCVLLHGSLKVEGMVAVVQLGPEWYGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGDDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKVASTGASEYTAYDHNIAPLQTDFPTTSTERM", "length": 517, "header": "tr|A0A8V0YWU1-1|INT14_CHICK Computationally mapped isoform of Integrator complex subunit 14 OS=Gallus gallus OX=9031 GN=INTS14 PE=2 SV=1 CANONICAL=Q5ZK21-1" }, "locus": { "chromosome": "10", "start_pos": 18092440, "end_pos": 18083671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043057.1", "url": "https://www.ensembl.org/id/ENSGALT00010043057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025547.1", "url": "https://www.ensembl.org/id/ENSGALP00010025547.1" } ] } }, { "isoform_ac": "Q5ZK21-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21/entry#Q5ZK21-1", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAVHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALLGVCNIVQQEWGAAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTSDVQVFPRPEPFIIDEEIDPIPKAINTDLEIVGFVDIADISSPPVLSRHLVLPIALNREGDEVGPGITDDTEDENSANQIAGKIPNFCVLLHGSLKVEGMVAVVQLGPEWYGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGDDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKVASTGASEYTAYDHNIAPLQTDFPTTSTERM", "length": 518, "header": "sp|Q5ZK21-1|INT14_CHICK Isoform 1 of Integrator complex subunit 14 OS=Gallus gallus OX=9031 GN=INTS14 PE=2 SV=1 CANONICAL=Q5ZK21-1" }, "locus": { "chromosome": "10", "start_pos": 18092440, "end_pos": 18083671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043060.1", "url": "https://www.ensembl.org/id/ENSGALT00010043060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025550.1", "url": "https://www.ensembl.org/id/ENSGALP00010025550.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:415540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415540", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1THU5-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHSQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPESFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSTERM", "length": 518 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HUX8-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVVKCGHLTADVQVFPRPEPFVTDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAAYDHNITPLHTDFSGSSTERM", "length": 518 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LWK5-1", "protein_name": "Integrator complex subunit 14", "gene_name": "ints14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVVLMDSSLSMTRPVSVEGSEEFQRKNLAVHGLTMLFEHMATNYKLEFTSLVAFSSLWELMVPFTRDYNTLQEALNNLEDYDKTCLEGALQGVSNVVQQEWGSACPCQVVLVTDGALGIGRGSLRHSLQTVKQRGEDKKFPLPFPFPSKLYIMCIANAEELQATDGMDNLEQLINLNGGDGQIYTMEGPLCLKSVQSMFGKLIDQAYSPFHAVLRCGNLTSDVQVFPRPEPVIIDEEVDPMPKNVQTDLEIVGFIEIGDISSPPVLSRHLVLPIAVNKEGDEIGTGTTDDTEEDTSTNQMAGKSPNFCVLLHGSLKVEGMVALVQLGPDWYGMLYSQADSKKKSNLMMSLFDPGSEPLPWLGRMSQLGPASDAAENPYGEDDSKSPFPIQPKHKRSYAQNVTVWIKASGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFWELLKSMAELLERECTLLPDSAHPDAAFQLSHAAQQLKLASSIDSKYAAFEHNITPMLTDFSGGGGDRI", "length": 518 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5EA76-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATHNQRGESNRFPLPFPFPSKLYIMCMANLEELQSTDSLDCLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMVQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTGTSEYAGYDHNITPLQTDFSGSSAERI", "length": 518 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66H58-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESSRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAALKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAVYDLNITPLHTDFSGSSTERM", "length": 515 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R3P6-1", "protein_name": "Integrator complex subunit 14", "gene_name": "Ints14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAIYDHNITPLHTDFSGSSTERM", "length": 515 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96SY0-1", "protein_name": "Integrator complex subunit 14", "gene_name": "INTS14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTVVVMDVSLSMTRPVSIEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPETAHPDAAFQLTHAAQQLKLASTGTSEYAAYDQNITPLHTDFSGSSTERI", "length": 518 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPY0-1", "protein_name": "Integrator complex subunit 14", "gene_name": "IntS14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTLIALDASLSMLRPVPGRNEHTYQSLATKGIQHLLDNLTAAGKLEHVALLSYSTTAELKVDFTRDYDQVRQAVKKVEPVDKACLMSMLKAVVSIMSPWGNQNILQVVVFTDCGLGFGNTSITGFLEAYAEKESEPEFGFLKTLANYNLNFICLGLHGDYYFTRGLAVYQQLLDKVSLKGQLFMTKPAKSSDAVEGNPNPNPNPSHKSELGRTTVFELIERLCEASYKSSEVTLKCGSYFRMEASVLLWPPTAPYEQKSHIFGREPTIRHTDQKIEVCGFLSLSDIGSPATLSRHWVLPKVEREKSGSSRRSGNLSAAAKPPKLNLDTSNPNYELEKLEADIKEFYAKDSKDTEESGDDDVTIVLKPGPQTEQQKENLCVLLHGALKMENMAALVRVGDKWYGFIYAFTDSKKKSNLMLNILPPGTNVIPWLGDLESLGFPEDLAPGETASFPVRADRRSYSQSSVVWIRQASLQSDVQKVLRHAKKMPDKTQHFYKELNRIRRAALALGFVELLEALAMLLEKECAHLSLNGASNDCTLQLQHAATELRKTSNRDMKSMIVPLQKVGASDAGSTAATAPAPAYMY", "length": 587 }, "evidence": [ { "id": "Q5ZK21", "url": "https://omabrowser.org/oma/group/Q5ZK21/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK21", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZK21-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 518, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZK21-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZK21" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "binding_site_uniprot": 10, "amino_acid": "Ser", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 10, "end_pos": 10, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "binding_site_uniprot": 12, "amino_acid": "Ser", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 12, "end_pos": 12, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZK21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK21" } ], "binding_site_uniprot": 86, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 86, "end_pos": 86, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZL35-1", "uniprot_ac": "Q5ZL35", "uniprot_id": "ARGL1_CHICK", "mass": { "chemical_mass": 33544.0, "monoisotopic_mass": 33544.0 }, "refseq": { "ac": "NP_001006267", "name": "arginine and glutamate-rich protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006267" }, "gene_names": [ { "name": "ARGLU1", "type": "recommended", "evidence": [ { "id": "Q5ZL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ] }, { "name": "ARGLU1", "type": "synonym", "evidence": [ { "id": "NP_001006267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006267" } ] }, { "name": "RCJMB04_7p10", "type": "synonym", "evidence": [ { "id": "Q5ZL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ] } ], "protein_names": [ { "name": "Arginine and glutamate-rich protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35/entry#names_and_taxonomy" } ] }, { "name": "arginine and glutamate-rich protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006267" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719899.1, HAEL01007942.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000025.1. On Jan 13, 2005 this sequence version replaced XP_416961.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006267", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006267" } ] }, { "annotation": "Dual function regulator of gene expression; regulator of transcription and modulator of alternative splicing. General coactivator of nuclear receptor-induced gene expression.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35#function" }, { "database": "UniProtKB", "id": "Q9NWB6", "url": "https://www.uniprot.org/uniprotkb/Q9NWB6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARGLU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35", "locus": { "chromosome": "1", "start_pos": 141084089, "end_pos": 141073870, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015016", "url": "https://www.ensembl.org/id/ENSGALG00010015016" } ] } } ], "crossref": [ { "id": "Q5ZL35", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL35", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016855", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016855", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418765", "url": "https://www.ncbi.nlm.nih.gov/gene/418765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418765", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNSHGRH", "url": "https://omabrowser.org/oma/group/VNSHGRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31711:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31711:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL35", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL35", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006267", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YXC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL35-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKNRSRSRSRSREKERARKRSKSRESKRNRRRESRSRSRSNTAPSSRRDRERERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLKIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKSQD", "length": 276, "header": "sp|Q5ZL35-1|ARGL1_CHICK Isoform 1 of Arginine and glutamate-rich protein 1 OS=Gallus gallus OX=9031 GN=ARGLU1 PE=2 SV=1 CANONICAL=Q5ZL35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC7/entry", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKNRSRSRSRSREKERARKRSKSRESKRNRRRESRSRSRSNTAPSSRRDRERERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREVTLGRLESRDSPWQNFQCRFVPPVRFRKRWNTTNLIPFSYKLLLLRNSIFSLFRGAH", "length": 251, "header": "tr|A0A8V0YXC7-1|ARGL1_CHICK Computationally mapped isoform of Arginine and glutamate-rich protein 1 OS=Gallus gallus OX=9031 GN=ARGLU1 PE=2 SV=1 CANONICAL=Q5ZL35-1" }, "locus": { "chromosome": "1", "start_pos": 141079878, "end_pos": 141074140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036103.1", "url": "https://www.ensembl.org/id/ENSGALT00010036103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020966.1", "url": "https://www.ensembl.org/id/ENSGALP00010020966.1" } ] } }, { "isoform_ac": "Q5ZL35-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35/entry#Q5ZL35-1", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKNRSRSRSRSREKERARKRSKSRESKRNRRRESRSRSRSNTAPSSRRDRERERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLKIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKSQD", "length": 276, "header": "sp|Q5ZL35-1|ARGL1_CHICK Isoform 1 of Arginine and glutamate-rich protein 1 OS=Gallus gallus OX=9031 GN=ARGLU1 PE=2 SV=1 CANONICAL=Q5ZL35-1" }, "locus": { "chromosome": "1", "start_pos": 141083371, "end_pos": 141074140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036110.1", "url": "https://www.ensembl.org/id/ENSGALT00010036110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020974.1", "url": "https://www.ensembl.org/id/ENSGALP00010020974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RFB3-1", "protein_name": "Arginine and glutamate rich 1", "gene_name": "ARGLU1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "PGTCGARNQRLVTASSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD", "length": 279 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TA42-1", "protein_name": "Arginine and glutamate-rich protein 1", "gene_name": "ARGLU1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD", "length": 273 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UL36-1", "protein_name": "Arginine and glutamate-rich protein 1", "gene_name": "Arglu1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNAAASRRERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD", "length": 271 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BJT0-1", "protein_name": "Arginine and glutamate-rich protein 1", "gene_name": "Arglu1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNAAASRRERERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD", "length": 271 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7ZVW9-1", "protein_name": "Arginine and glutamate-rich protein 1-B", "gene_name": "arglu1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGRSRSRSSSRSKHSKTSKHSKKRSRSRSRSRDRERKRRSKSRESKRNRRRESRSRSRSNTATSRRDRERAASPPERIDIFGRALSKRSAVDEKQKKEEEEKKVEMERQRRIRQQEIEERLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRHAELAAQKAREEEEKSKREELEKILVDNNRKIADAQAKLAEDQLRIVEEQRKIHEERMKLEQERQKQQKEEQKMILGKGKSRPKLSFSLKASE", "length": 269 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9LYU2-1", "protein_name": "Arginine/glutamate-rich 1 protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARNDSRSRSPSHRRRYSRSPVTHRSSRRTRRDRSRSPYTSRHKKSRSPAPRQHQRDRSSSLSPSEHRIAIEVKKEQEDKARLQHEAELKRLEEETAQRIEEAVRKNVEERMKTEEVKEEIERRTKEAYEKMFLDVEIQLKKEKEAALNEARRKEEQARREREELDKMLEENSRRVEESQRREAMELQRKEEERYRELELLQRQKEEAARRKKLEEEEEIRNSSKLSNGNRSRSKLHFGMGL", "length": 242 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NWB6-1", "protein_name": "Arginine and glutamate-rich protein 1", "gene_name": "ARGLU1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRSRSRSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD", "length": 273 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VL63-1", "protein_name": "Arginine and glutamate-rich protein 1", "gene_name": "Arglu1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSRSRTPSPSGKRRHHKSKHKKRSKSHHDHERPSTRTDRDKSSEVNNHGRHRERDRDRERDRHRSDRHTERDYRHSPSILKSRKRSSSSSSDSQYSEQESQRSKQKRSRFKKLDEQNQMQVERLAEMERQRRAKELEQKTIEEEAAKRIEMLVKKRVEEELEKRRDEIEQEVNRRVETAKAEMEREMMLELERRREQIREEERRREEDEKQKREELEEILAENNRKIEEAQRKLAEERLAIIEEQRLMDEERQRMRKEQEKRVKEEQKVILGKNNSRPKLSFSLKPGAL", "length": 290 }, "evidence": [ { "id": "Q5ZL35", "url": "https://omabrowser.org/oma/group/Q5ZL35/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL35", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZL35-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 276, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZL35-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZL35" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL35" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "LXXLL motif 1; degenerate", "eco_id": "ECO_0000250", "start_pos": 175, "end_pos": 179, "start_aa": "Leu", "end_aa": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLR7-1", "uniprot_ac": "Q5ZLR7", "uniprot_id": "LYSET_CHICK", "mass": { "chemical_mass": 15363.0, "monoisotopic_mass": 15363.0 }, "refseq": {}, "gene_names": [ { "name": "LYSET", "type": "recommended", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ] }, { "name": "TMEM251", "type": "recommended", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ] }, { "name": "C14orf109", "type": "synonym", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ] }, { "name": "RCJMB04_5b13", "type": "synonym", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ] }, { "name": "TMEM251", "type": "synonym", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ] } ], "protein_names": [ { "name": "Lysosomal enzyme trafficking factor", "type": "recommended", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 251", "type": "synonym", "evidence": [ { "id": "Q5ZLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for mannose-6-phosphate-dependent trafficking of lysosomal enzymes. LYSET bridges GlcNAc-1-phosphate transferase (GNPTAB), to the membrane-bound transcription factor site-1 protease (MBTPS1), thus allowing proteolytic activation of the GNPTAB. GNPTAB is involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes. LYSET is thus an essential factor for maturation and delivery of lysosomal hydrolases.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7#function" }, { "database": "UniProtKB", "id": "Q8N6I4", "url": "https://www.uniprot.org/uniprotkb/Q8N6I4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYSET", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7", "locus": {} } ], "crossref": [ { "id": "Q5ZLR7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000051040", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000051040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423422", "url": "https://www.ncbi.nlm.nih.gov/gene/423422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423422", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYYIFEV", "url": "https://omabrowser.org/oma/group/AYYIFEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY25", "url": "https://www.orthodb.org/?gene=A0A8V0YY25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLR7", "url": "https://www.orthodb.org/?gene=Q5ZLR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31925", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31925", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31925:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31925:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLR7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLR7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A8V0YY25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLR7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNKLALEHIQQHPQEPQEGTTWTHSLKVRLLSLPFWLWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQTFVKASNQISRLQLIDT", "length": 131, "header": "sp|Q5ZLR7-1|LYSET_CHICK Isoform 1 of Lysosomal enzyme trafficking factor OS=Gallus gallus OX=9031 GN=LYSET PE=2 SV=2 CANONICAL=Q5ZLR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY25/entry", "sequence": { "sequence": "MGCRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNKLALEHIQQHPQEPQEGTTWTHSLKVRLLSLPFWLWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQTFVKASNQISRLQLIDT", "length": 138, "header": "tr|A0A8V0YY25-1|LYSET_CHICK Computationally mapped isoform of Lysosomal enzyme trafficking factor OS=Gallus gallus OX=9031 GN=LYSET PE=2 SV=1 CANONICAL=Q5ZLR7-1" }, "locus": { "chromosome": "5", "start_pos": 44566853, "end_pos": 44566142, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040728.1", "url": "https://www.ensembl.org/id/ENSGALT00010040728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023693.1", "url": "https://www.ensembl.org/id/ENSGALP00010023693.1" } ] } }, { "isoform_ac": "Q5ZLR7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7/entry#Q5ZLR7-1", "sequence": { "sequence": "MMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNKLALEHIQQHPQEPQEGTTWTHSLKVRLLSLPFWLWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQTFVKASNQISRLQLIDT", "length": 131, "header": "sp|Q5ZLR7-1|LYSET_CHICK Isoform 1 of Lysosomal enzyme trafficking factor OS=Gallus gallus OX=9031 GN=LYSET PE=2 SV=2 CANONICAL=Q5ZLR7-1" }, "locus": { "chromosome": "5", "start_pos": 44566853, "end_pos": 44566461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040734.1", "url": "https://www.ensembl.org/id/ENSGALT00010040734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023699.1", "url": "https://www.ensembl.org/id/ENSGALP00010023699.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423422", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2C9F370-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "LYSET", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVASSEMPKPPDYSELSDSLTLPVGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHIQQHPEEPLEGTTWTHSLKSRLLSLPFWFWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "length": 169 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LXS7-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "Lyset", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKAPDYSELSDSCTLAGGTARFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHIQQHPEEPREGTTWTHSLKARLLSLPFWLWTVIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAIICNRHQAFVKASNQISRLQLIDT", "length": 163 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2HJ69-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "LYSET", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKPPDYSELSDSLTLAVGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHIQQHPEEPLEGTTWTHSLKTRLLSLPFWFWTVVFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "length": 163 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TZA3-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "tmem251", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMNFRQRMGWIGVGLYLLASVAAVYYIFEISQTYNRLALAQVEKTSGAQAKWPGDASSSSPSSTSWIVTLKTRLLLLPFWVWATIFLLPYLQVFLFLYSCTRADPKTVGYCILPICLAVLCNRHQTFTKASNQISRLQLIDT", "length": 142 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BH26-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "Lyset", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKAPDCSELSDSCSLAGGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHILQHPEEPREGTTWTHSLKARLLSLPFWLWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "length": 163 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N6I4-1", "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "LYSET", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKPPDYSELSDSLTLAVGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEISETYNRLALEHIQQHPEEPLEGTTWTHSLKAQLLSLPFWVWTVIFLVPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "length": 163 }, "evidence": [ { "id": "Q5ZLR7", "url": "https://omabrowser.org/oma/group/Q5ZLR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" }, { "name": "regulation of vesicle-mediated transport", "id": "GO:0060627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060627", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" }, { "name": "lysosomal transport", "id": "GO:0007041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007041", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLR7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 131, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLR7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLY2-1", "uniprot_ac": "Q5ZLY2", "uniprot_id": "HAGHL_CHICK", "mass": { "chemical_mass": 32228.0, "monoisotopic_mass": 32228.0 }, "refseq": { "ac": "NP_001025808", "name": "hydroxyacylglutathione hydrolase-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808" }, "gene_names": [ { "name": "HAGHL", "type": "recommended", "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ] }, { "name": "HAGHL", "type": "synonym", "evidence": [ { "id": "NP_001025808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808" } ] }, { "name": "RCJMB04_21j14", "type": "synonym", "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ] }, { "name": "RCJMB04_4h5", "type": "synonym", "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ] } ], "protein_names": [ { "name": "Hydroxyacylglutathione hydrolase-like protein", "type": "recommended", "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.-", "type": "synonym", "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2/entry#names_and_taxonomy" } ] }, { "name": "RCJMB04_4h5", "type": "synonym", "evidence": [ { "id": "NP_001025808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808" } ] }, { "name": "hydroxyacylglutathione hydrolase-like protein", "type": "synonym", "evidence": [ { "id": "NP_001025808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719602.1, AJ851726.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Aug 8, 2005 this sequence version replaced XP_414837.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808" } ] }, { "annotation": "Hydrolase acting on ester bonds.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAGHL", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2", "locus": { "chromosome": "14", "start_pos": 6042277, "end_pos": 6046026, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018607", "url": "https://www.ensembl.org/id/ENSGALG00010018607" } ] } } ], "crossref": [ { "id": "Q5ZLY2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021040", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416536", "url": "https://www.ncbi.nlm.nih.gov/gene/416536", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416536", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416536", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKERARF", "url": "https://omabrowser.org/oma/group/CKERARF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z105", "url": "https://www.orthodb.org/?gene=A0A8V0Z105", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Y5", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLY2", "url": "https://www.orthodb.org/?gene=Q5ZLY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11935:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11935:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLY2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLY2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z105", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z105", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z105-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z105-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLY2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVKVISVLEDNYMYLVIEESTRDAVAVDAAVPKRLLEIVRKEDVVLRAVLITHHHWDHARGNEELVRLCPGLRVYGADERIGALTHRVAPDEELTFGAIRVRCLFTPCHTKGHMCYFMWEDGSLDAPALFSGDTLFVGGCGQFLEGTAEQMYTNLTQVLGDLPKETKVFCGHECTVRNLKFALKVEPENEAVKKKLAWARQRDDEDLPTVPSTLQEEFLYNPFLRVTEEAVQKFTGRKEPVEVLRALRTEKDNFKKPKERPHPQAMLAFDWGLFAPFLEKK", "length": 282, "header": "sp|Q5ZLY2-1|HAGHL_CHICK Isoform 1 of Hydroxyacylglutathione hydrolase-like protein OS=Gallus gallus OX=9031 GN=HAGHL PE=2 SV=1 CANONICAL=Q5ZLY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z105-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z105/entry", "sequence": { "sequence": "MKVKVISVLEDNYMYLVIEESTRDAVAVDAAVPKRLLEIVRKEDVVLRAVLITHHHWDHARGNEELVRLCPGLRVYGADERIGALTHRVAPDEELTFGAIRVRCLFTPCHTKGHMCYFMWEDGSLDAPALFSGDTLFVGGCGQFLEGTAEQMYTNLTQVLGDLPKETKVFCGHECTVRNLKFALKVEPENEAVKKKLAWARGGGCAEVHRQEGAGGSAAGSTHREGQLQEAQGAAPSPGHARLRLGALCPFPGEEVRLHHPTTQGSTERRHTLGSAAQNPQCCTDGPAQVSLSPRLGQGRDPGTAPLRVHCISFSQGRTQESYCTKH", "length": 327, "header": "tr|A0A8V0Z105-1|HAGHL_CHICK Computationally mapped isoform of Hydroxyacylglutathione hydrolase-like protein OS=Gallus gallus OX=9031 GN=HAGHL PE=2 SV=1 CANONICAL=Q5ZLY2-1" }, "locus": { "chromosome": "14", "start_pos": 6045894, "end_pos": 6043657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045026.1", "url": "https://www.ensembl.org/id/ENSGALT00010045026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026897.1", "url": "https://www.ensembl.org/id/ENSGALP00010026897.1" } ] } }, { "isoform_ac": "A0A8V0Z6Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Y5/entry", "sequence": { "sequence": "MKVKVISVLEDNYMYLVIEESTRDAVAVDAAVPKRLLEIVRKEDVVLRAVLITHHHCPFVGVPGAHCPVLSPSRAQRSSLSPQFGAIRVRCLFTPCHTKGHMCYFMWEDGSLDAPALFSGDTLFVGGCGQFLEGTAEQMYTNLTQVLGDLPKETKVFCGHECTVRNLKFALKVEPENEAVKKKLAWARQRDDEDLPTVPSTLQEEFLYNPFLRVTEEAVQKFTGRKEPVEVLRALRTEKDNFKKPKERPHPQAMLAFDWGLFAPFLEKK", "length": 269, "header": "tr|A0A8V0Z6Y5-1|A0A8V0Z6Y5_CHICK Computationally mapped isoform of Hydroxyacylglutathione hydrolase like OS=Gallus gallus OX=9031 GN=HAGHL PE=1 SV=1 CANONICAL=Q5ZLY2-1" }, "locus": { "chromosome": "14", "start_pos": 6045894, "end_pos": 6043872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045043.1", "url": "https://www.ensembl.org/id/ENSGALT00010045043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026910.1", "url": "https://www.ensembl.org/id/ENSGALP00010026910.1" } ] } }, { "isoform_ac": "Q5ZLY2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2/entry#Q5ZLY2-1", "sequence": { "sequence": "MKVKVISVLEDNYMYLVIEESTRDAVAVDAAVPKRLLEIVRKEDVVLRAVLITHHHWDHARGNEELVRLCPGLRVYGADERIGALTHRVAPDEELTFGAIRVRCLFTPCHTKGHMCYFMWEDGSLDAPALFSGDTLFVGGCGQFLEGTAEQMYTNLTQVLGDLPKETKVFCGHECTVRNLKFALKVEPENEAVKKKLAWARQRDDEDLPTVPSTLQEEFLYNPFLRVTEEAVQKFTGRKEPVEVLRALRTEKDNFKKPKERPHPQAMLAFDWGLFAPFLEKK", "length": 282, "header": "sp|Q5ZLY2-1|HAGHL_CHICK Isoform 1 of Hydroxyacylglutathione hydrolase-like protein OS=Gallus gallus OX=9031 GN=HAGHL PE=2 SV=1 CANONICAL=Q5ZLY2-1" }, "locus": { "chromosome": "14", "start_pos": 6045894, "end_pos": 6043872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045037.1", "url": "https://www.ensembl.org/id/ENSGALT00010045037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026906.1", "url": "https://www.ensembl.org/id/ENSGALP00010026906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416536", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L628-1", "protein_name": "Hydroxyacylglutathione hydrolase-like", "gene_name": "Haghl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVKVIPVLEDNYMYLIIEEHTREAVAVDVAVPKRLLEIAGREGVSLTTVLSTHHHWDHTRGNAELARLQPGLAIMGADERICALTRRLEHGEELQFGAIHVRCLLTPGHTSGHMSYFLWEDECPDPPALFSGTLQPGLTYQPNSTVSSRPPSDPLCSLGDALSVAGCGWHLEDTAQQMYQSLAKTLGTLPPQTKVFCGHEHTLSNLEFAQKVEPCNSHVQAKLSWAQKRDDDDVPTVPSTLGEELMYNPFLRVTEDPVRAFTGQVAPAQVLEVLCRERARFQLASEPPQPQVRALLALQWGLLSTGQEK", "length": 310 }, "evidence": [ { "id": "Q5ZLY2", "url": "https://omabrowser.org/oma/group/Q5ZLY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05584-1", "protein_name": "Hydroxyacylglutathione hydrolase, cytoplasmic isozyme", "gene_name": "GLO2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQVKSIKMRWESGGVNYCYLLSDSKNKKSWLIDPAEPPEVLPELTEDEKISVEAIVNTHHHYDHADGNADILKYLKEKNPTSKVEVIGGSKDCPKVTIIPENLKKLHLGDLEITCIRTPCHTRDSICYYVKDPTTDERCIFTGDTLFTAGCGRFFEGTGEEMDIALNNSILETVGRQNWSKTRVYPGHEYTSDNVKFVRKIYPQVGENKALDELEQFCSKHEVTAGRFTLKDEVEFNPFMRLEDPKVQKAAGDTNNSWDRAQIMDKLRAMKNRM", "length": 274 }, "evidence": [ { "id": "Q5ZLY2", "url": "https://omabrowser.org/oma/group/Q5ZLY2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6PII5-1", "protein_name": "Hydroxyacylglutathione hydrolase-like protein", "gene_name": "HAGHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAELGTLPPETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACGHSRRGMRMTCPLCRRLWARSASTTPSCGWREYGCCPGASTVTWTLRKASGDCVLG", "length": 290 }, "evidence": [ { "id": "Q5ZLY2", "url": "https://omabrowser.org/oma/group/Q5ZLY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB32-1", "protein_name": "Hydroxyacylglutathione hydrolase-like protein", "gene_name": "Haghl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVKVIPVLEDNYMYLIIEEHTREAVAIDVAVAERLLEIAGREGVSLTMVLSTHHHWDHTRGNAELAHILPGLAVLGADERICALTRRLEHGEGLQFGAIHVRCLLTPGHTSGHMSYFLWEDDCPDSPALFSGDALSVAGCGWHLEDTAQQMYQSLAKTLGTLPPETKVFCGHEHTLSNLEFAQKVEPCNEHVQAKLSWAQERDDEDIPTVPSTLGEELMYNPFLRVTEDAVRAFTGQVAPAQVLEALCRERARFQPAVEPPQPQVRALLALQWGLLSTHQKK", "length": 283 }, "evidence": [ { "id": "Q5ZLY2", "url": "https://omabrowser.org/oma/group/Q5ZLY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydroxyacylglutathione hydrolase activity", "id": "GO:0004416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004416", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "id": "GO:0019243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019243", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLY2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLY2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 282, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLY2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLY2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "binding_site_uniprot": 110, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 110, "end_pos": 110, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "binding_site_uniprot": 134, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 134, "end_pos": 134, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLY2" } ], "binding_site_uniprot": 173, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": 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record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Aug 8, 2005 this sequence version replaced XP_417620.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026051", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026051" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK25", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SZRD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25", "locus": { "chromosome": "21", "start_pos": 4381469, "end_pos": 4367297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020321", "url": "https://www.ensembl.org/id/ENSGALG00010020321" } ] } } ], "crossref": [ { "id": "Q5ZK25", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZK25", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZK25", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZK25", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026051", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026051", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z701", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z701-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z701-1", "database": 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"MEDEEVAESWEEAADSGEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 152, "header": "sp|Q5ZK25-1|SZRD1_CHICK Isoform 1 of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=2 SV=1 CANONICAL=Q5ZK25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z8/entry", "sequence": { "sequence": "MNASQLPFHPALRLQPAEIDRRLEKKLKITQKESSRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 153, "header": "tr|A0A8V0Z6Z8-1|A0A8V0Z6Z8_CHICK Computationally mapped isoform of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=3 SV=1 CANONICAL=Q5ZK25-1" }, "locus": { "chromosome": "21", "start_pos": 4379005, "end_pos": 4376849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049059.1", "url": "https://www.ensembl.org/id/ENSGALT00010049059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029008.1", "url": "https://www.ensembl.org/id/ENSGALP00010029008.1" } ] } }, { "isoform_ac": "A0A8V0Z701-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z701/entry", "sequence": { "sequence": "MLGRSNRPAVRSLRWERVAMSSAFQGGTWVVLPPCWEGRQGEAAMLGEEGSCEEKVAGWFLGCERTVLWLCARPAAGQHSFSFPLEKARGWEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 226, "header": "tr|A0A8V0Z701-1|A0A8V0Z701_CHICK Computationally mapped isoform of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=3 SV=1 CANONICAL=Q5ZK25-1" }, "locus": { "chromosome": "21", "start_pos": 4379005, "end_pos": 4367364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049071.1", "url": "https://www.ensembl.org/id/ENSGALT00010049071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029014.1", "url": "https://www.ensembl.org/id/ENSGALP00010029014.1" } ] } }, { "isoform_ac": "A0A8V0ZCS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS6/entry", "sequence": { "sequence": "MLSAFGKLRSLISGSSELQWGLLGDGIEMTPCNYRIWPSEEIDRRLEKKLKITQKESSRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 176, "header": "tr|A0A8V0ZCS6-1|A0A8V0ZCS6_CHICK Computationally mapped isoform of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=3 SV=1 CANONICAL=Q5ZK25-1" }, "locus": { "chromosome": "21", "start_pos": 4379005, "end_pos": 4373365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049066.1", "url": "https://www.ensembl.org/id/ENSGALT00010049066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029010.1", "url": "https://www.ensembl.org/id/ENSGALP00010029010.1" } ] } }, { "isoform_ac": "A0A8V0ZE70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE70/entry", "sequence": { "sequence": "MALSAEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 140, "header": "tr|A0A8V0ZE70-1|A0A8V0ZE70_CHICK Computationally mapped isoform of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=3 SV=1 CANONICAL=Q5ZK25-1" }, "locus": { "chromosome": "21", "start_pos": 4379005, "end_pos": 4369392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049067.1", "url": "https://www.ensembl.org/id/ENSGALT00010049067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029011.1", "url": "https://www.ensembl.org/id/ENSGALP00010029011.1" } ] } }, { "isoform_ac": "Q5ZK25-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25/entry#Q5ZK25-1", "sequence": { "sequence": "MEDEEVAESWEEAADSGEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSVPSGPPPQIRILKRPATNGVLSNPNSTTRPAFPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDIRQPNNVIRQPLGPDGSQGFKQRR", "length": 152, "header": "sp|Q5ZK25-1|SZRD1_CHICK Isoform 1 of SUZ RNA-binding domain-containing OS=Gallus gallus OX=9031 GN=SZRD1 PE=2 SV=1 CANONICAL=Q5ZK25-1" }, "locus": { "chromosome": "21", "start_pos": 4379005, "end_pos": 4369057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049069.1", "url": "https://www.ensembl.org/id/ENSGALT00010049069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029013.1", "url": "https://www.ensembl.org/id/ENSGALP00010029013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK25", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419462", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419462", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZK25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 152, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZK25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZK25" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZK25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25" }, { "id": "PRU01009", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUZ", "eco_id": "ECO_0000255", "start_pos": 42, "end_pos": 107, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5ZK25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK25" }, { "id": "PRU01287", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUZ-C", "eco_id": "ECO_0000255", "start_pos": 111, "end_pos": 152, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000257.1. 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"id": "ENSGALT00010052355.1", "url": "https://www.ensembl.org/id/ENSGALT00010052355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031283.1", "url": "https://www.ensembl.org/id/ENSGALP00010031283.1" } ] } }, { "isoform_ac": "A0A8V0ZR94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR94/entry", "sequence": { "sequence": "MAHSAPLGLLEQGCPIQVEHDRKRRQFTVRLNGTCQALCRAACVPGDSSLGLLLCHPAPRTPSQRTALQSPLFPCQGCHDRAVLLYEYVGKRIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVKENPLPQYLEHLQP", "length": 154, "header": "tr|A0A8V0ZR94-1|A0A8V0ZR94_CHICK Computationally mapped isoform of Protein NATD1 OS=Gallus gallus OX=9031 GN=NATD1 PE=3 SV=1 CANONICAL=Q5ZJI6-1" }, "locus": { "chromosome": "14", "start_pos": 4526768, "end_pos": 4523453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052356.1", "url": "https://www.ensembl.org/id/ENSGALT00010052356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031284.1", "url": "https://www.ensembl.org/id/ENSGALP00010031284.1" } ] } }, { "isoform_ac": "Q5ZJI6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJI6/entry#Q5ZJI6-1", "sequence": { "sequence": "MAHSAPLGLLEQGCPIQVEHDRKRRQFTVRLNGCHDRAVLLYEYVGKRIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVKENPLPQYLEHLQP", "length": 110, "header": "sp|Q5ZJI6-1|NATD1_CHICK Isoform 1 of Protein NATD1 OS=Gallus gallus OX=9031 GN=NATD1 PE=3 SV=1 CANONICAL=Q5ZJI6-1" }, "locus": { "chromosome": "14", "start_pos": 4526768, "end_pos": 4523453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052358.1", "url": "https://www.ensembl.org/id/ENSGALT00010052358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031286.1", "url": "https://www.ensembl.org/id/ENSGALP00010031286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZIL9-1", "uniprot_ac": "Q5ZIL9", "uniprot_id": "KBP_CHICK", "mass": { "chemical_mass": 69081.0, "monoisotopic_mass": 69081.0 }, "refseq": { "ac": "NP_001007945", "name": "KIF-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" }, "gene_names": [ { "name": "KIF1BP", "type": "recommended", "evidence": [ { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ] }, { "name": "Kifbp", "type": "recommended", "evidence": [ { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ] }, { "name": "KIAA1279", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "name": "KIF1BP", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "name": "Kifbp", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "name": "RCJMB04_25c4", "type": "synonym", "evidence": [ { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ] }, { "name": "kbp", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" }, { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ] } ], "protein_names": [ { "name": "KIF-binding protein", "type": "recommended", "evidence": [ { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9/entry#names_and_taxonomy" } ] }, { "name": "KIF-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "name": "KIF1-binding protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001007945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "name": "KIF1-binding protein", "type": "synonym", "evidence": [ { "id": "Q5ZIL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720765.1, HAEK01017664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000229.1. On Dec 15, 2004 this sequence version replaced XP_421575.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007945", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945" } ] }, { "annotation": "Activator of KIF1B plus-end-directed microtubule motor activity. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9#function" }, { "database": "UniProtKB", "id": "Q96EK5", "url": "https://www.uniprot.org/uniprotkb/Q96EK5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZUW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW0#function" }, { "database": "UniProtKB", "id": "ARBA00045179", "url": "https://www.uniprot.org/uniprotkb/ARBA00045179#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "Kifbp", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9", "locus": {} } ], "crossref": [ { "id": "Q5ZIL9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004156", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004156", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423694", "url": "https://www.ncbi.nlm.nih.gov/gene/423694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423694", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICRECWY", "url": "https://omabrowser.org/oma/group/ICRECWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUW0", "url": "https://www.orthodb.org/?gene=A0A8V0ZUW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIL9", "url": "https://www.orthodb.org/?gene=Q5ZIL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46321:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46321:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIL9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIL9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007945", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007945", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIL9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGGWAAACEKFRSARTLSAVESRKDPETEPYRSKYSARALLQEVKQQLSAAEDCGEARLLAVRRAVLEYELGVNHTDTEELSAGEEHLQRCTQLLEPHRLSRDCVSLYIQAQNNLGILWSERDEIKTAQTYLESAEALYNQYMKEDGNPPLDPSEHFMAEEEKLTDQERSKRFEKAYTHTLYYLAQVYQHLEMIEKAAQYCHTTLKRQLEYCGYYPVEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQAGQVPSTEDNETEQDQQDLRQRKAEIARCWIKYCLNLLQSARKLLEDNIGELDPDRQLELKAQRKKEEDEKENGRKKAVLFGTSDICDSVLAMEEKVSSVYPLDFQEAREIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYADLNPQYYLLISRQLQFELADTYYEMMDLKVAIGNRLEELDSHTIKKINSLAQLAIKYYELFLDSLRNPDKVFPEELEEDVLRPAMVAKFHIARLYGKLITSDSKKQLENMQTSLEYYTFLVDYCEKHPDAVRAVETELELSKEMVGLLPTRMERLRAKLCPFI", "length": 594, "header": "sp|Q5ZIL9-1|KBP_CHICK Isoform 1 of KIF-binding protein OS=Gallus gallus OX=9031 GN=Kifbp PE=2 SV=1 CANONICAL=Q5ZIL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW0/entry", "sequence": { "sequence": "MAAAGGGWAAACEKFRSARTLSAVESRKDPETEPYRSKYSARALLQELGVNHTDTEELSAGEEHLQRCTQLLEPHRLSRDCVSLYIQAQNNLGILWSERDEIKTAQTYLESAEALYNQYMKEDGNPPLDPSEHFMAEEEKLTDQERSKRFEKAYTHTLYYLAQVYQHLEMIEKAAQYCHTTLKRQLEYCGYYPVEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQAGQVPSTEDNETEQDQQDLRQRKAEIARCWIKYCLNLLQSARKLLEDNIGELDPDRQLELKAQRKKEEDEKENGRKKAVLFGTSDICDSVLAMEEKVSSVYPLDFQEAREIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYADLNPQYYLLISRQLQFELADTYYEMMDLKVAIGNRLEELDSHTIKKINSLAQLAIKYYELFLDSLRNPDKVFPEELEEDVLRPAMVAKFHIARLYGKLITSDSKKQLENMQTSLEYYTFLVDYCEKHPDAVRAVETELELSKEMVGLLPTRMERLRAKLCPFI", "length": 567, "header": "tr|A0A8V0ZUW0-1|KBP_CHICK Computationally mapped isoform of KIF-binding protein OS=Gallus gallus OX=9031 GN=Kifbp PE=2 SV=1 CANONICAL=Q5ZIL9-1" }, "locus": { "chromosome": "6", "start_pos": 11567556, "end_pos": 11559344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056511.1", "url": "https://www.ensembl.org/id/ENSGALT00010056511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034253.1", "url": "https://www.ensembl.org/id/ENSGALP00010034253.1" } ] } }, { "isoform_ac": "Q5ZIL9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9/entry#Q5ZIL9-1", "sequence": { "sequence": "MAAAGGGWAAACEKFRSARTLSAVESRKDPETEPYRSKYSARALLQEVKQQLSAAEDCGEARLLAVRRAVLEYELGVNHTDTEELSAGEEHLQRCTQLLEPHRLSRDCVSLYIQAQNNLGILWSERDEIKTAQTYLESAEALYNQYMKEDGNPPLDPSEHFMAEEEKLTDQERSKRFEKAYTHTLYYLAQVYQHLEMIEKAAQYCHTTLKRQLEYCGYYPVEWALNAATLSQYYLSKQCFMESRHCLAAASVIFSQAGQVPSTEDNETEQDQQDLRQRKAEIARCWIKYCLNLLQSARKLLEDNIGELDPDRQLELKAQRKKEEDEKENGRKKAVLFGTSDICDSVLAMEEKVSSVYPLDFQEAREIFLVGQNYVQEAKEFFQVDGYVTDHIEIVQDHSALFKVLAFFEEDYERRCKMHKRRIDMLEPIYADLNPQYYLLISRQLQFELADTYYEMMDLKVAIGNRLEELDSHTIKKINSLAQLAIKYYELFLDSLRNPDKVFPEELEEDVLRPAMVAKFHIARLYGKLITSDSKKQLENMQTSLEYYTFLVDYCEKHPDAVRAVETELELSKEMVGLLPTRMERLRAKLCPFI", "length": 594, "header": "sp|Q5ZIL9-1|KBP_CHICK Isoform 1 of KIF-binding protein OS=Gallus gallus OX=9031 GN=Kifbp PE=2 SV=1 CANONICAL=Q5ZIL9-1" }, "locus": { "chromosome": "6", "start_pos": 11567556, "end_pos": 11559344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056514.1", "url": "https://www.ensembl.org/id/ENSGALT00010056514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034256.1", "url": "https://www.ensembl.org/id/ENSGALP00010034256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423694", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423694", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TLJ5-1", "protein_name": "KIF-binding protein", "gene_name": "KIFBP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADAPWVELREKFQAALALSRVELHKNPEKEPYKSKYHARALLEEVKALLGPAPEDEDDRPQAEDSLGTGDHTLGLPAELVEAEGPIALGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRMSQDCVSLYIQAQNNLGILWSEREEIESAQAYLESSEALYNQYMKEIGSPPLDPTEHFLSEEEKLAEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQTGKISTMEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCERHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3SYS9-1", "protein_name": "KIF-binding protein", "gene_name": "KIFBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADSPWDEIREKFQTALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPQADDSLGAGEHALGLPAELVEAEGPVAQGAVRRAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRKYRLSHDCVSLYIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEIGSPPLDPTEHFLPEEEKLPEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKQCFMEARHCLSAANVIFGQIGKIRTTEDTTEAEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLTGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G074-1", "protein_name": "KIF-binding protein", "gene_name": "Kifbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDDDERAADDGPVDQALGAGEPRDAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLFIQAQNNLGILWSEREEIETARTYLESSEALYNQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKITATEDTPEVEGDMPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRRKELDEEESVRKRAVQFGTGELRDAISAVEEKVRYLRPLDFEEARELFLLGQHYVYEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFEADMERRCKMHKRRIAMLEPLIVDLNPQYYQLVNRQIQFEIAHAYYDMMDLKVAIADKLREPDSHTVKKINSLNQSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT", "length": 617 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZPU9-1", "protein_name": "KIF-binding protein", "gene_name": "Kifbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDEDEPAADDGPGDQALGAGEPREAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLYIQAQNNLGILWSEREEIETARTYLESSEALYSQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKIPATEDTPEVEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKRAVQFGTGELCDAISAVEEKVRYLRPLDFEEARELFLLGQHYVCEAKEFFQIDGYVTDHIEVVQDHSALFKVLSFFEADMERRCKMHKRRIAMLEPLTVDLNPQYYLLVSRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINSLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT", "length": 617 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EK5-1", "protein_name": "KIF-binding protein", "gene_name": "KIFBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT", "length": 621 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VMX1-1", "protein_name": "KIF-binding protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVIPKEILSDFKELYEKANRLVEEESRNDPPTDPFRSHYKARDVLIVLKKQLDDQLVSVQASEEDGGQDDRCYHSLLAFVCRDLGRIYIYTEEQAEGEKMLNRCLELVTPFKECPEGIIPFIGAINELSIVLASKEEYNKGLEILLEAEKIYEDFKASGLKPLAIQDVFNPPEEGQQSHEAGPKELESLYTLVSFYMAQMYGHLGEPEKSAKCCHRTLHRQLESKTYDPIDFALNTATLSQFYIGEKRFEEARHHLAAATLIMAEYEVHMLEPEMSEKQRQDVSETFKHRYADVARCWAKYGLYLMNTSKLRLMRDEDDEDAKNLEIVLRNMRLVEAEQSRFPGLDLTACENRISCEYCLTFDDAKLVFHFVNEWLDIAKDYYKAENEATEYSKIMQDYAEAYEHIAFFEENPENQAKMQKRRAKYLEDLLDLLDPIFYMKICRECWYGAGTAHAAVMDVRLDIIRATSTPAPEDIKKVNQSCMKAIKHFESYVKSYLVKPPSEEWRPNMDVEEQRHMLYAHFHIGRIYYKLISGHPLQQLEHLTSCHTYYQRFDAGCQLHKEAAETLQGEIGVVREMLQLLPLKINTIKARLNKAGLTA", "length": 600 }, "evidence": [ { "id": "Q5ZIL9", "url": "https://omabrowser.org/oma/group/Q5ZIL9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" }, { "name": "neuron projection maintenance", "id": "GO:1990535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990535", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 594, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIL9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3S2-1", "uniprot_ac": "Q5F3S2", "uniprot_id": "PKHB2_CHICK", "mass": { "chemical_mass": 25410.0, "monoisotopic_mass": 25410.0 }, "refseq": { "ac": "NP_001026473", "name": "pleckstrin homology domain-containing family B member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" }, "gene_names": [ { "name": "PLEKHB2", "type": "recommended", "evidence": [ { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ] }, { "name": "EVT2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" }, { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ] }, { "name": "PLEKHB2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" } ] }, { "name": "RCJMB04_8b5", "type": "synonym", "evidence": [ { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family B member 2", "type": "recommended", "evidence": [ { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2/entry#names_and_taxonomy" } ] }, { "name": "Evectin-2", "type": "synonym", "evidence": [ { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2/entry#names_and_taxonomy" } ] }, { "name": "PH domain-containing family B member 2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" }, { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2/entry#names_and_taxonomy" } ] }, { "name": "evectin-2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" } ] }, { "name": "pleckstrin homology domain containing, family B (evectins) member 2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" } ] }, { "name": "pleckstrin homology domain-containing family B member 2", "type": "synonym", "evidence": [ { "id": "NP_001026473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851578.1, SRR13267649.140609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992639 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Aug 8, 2005 this sequence version replaced XP_422580.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026473", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473" } ] }, { "annotation": "Involved in retrograde transport of recycling endosomes.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHB2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2", "locus": { "chromosome": "9", "start_pos": 1851722, "end_pos": 1865952, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024174", "url": "https://www.ensembl.org/id/ENSGALG00010024174" } ] } } ], "crossref": [ { "id": "Q5F3S2", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424758", "url": "https://www.ncbi.nlm.nih.gov/gene/424758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424758", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424758", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIGSEVM", "url": "https://omabrowser.org/oma/group/YIGSEVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWB6", "url": "https://www.orthodb.org/?gene=A0A8V0ZWB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5F3S2", "url": "https://www.orthodb.org/?gene=Q5F3S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14309:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14309:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3S2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3S2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026473", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3S2-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFVKSGWLLRQSTILRRWKKNWFDLWSDGRLIFYDDQNRHDIEDKIHMRIHCINLRVGNECRDFQPPEGKQRDCLLQIVCRDGKTVNLCAESADDCLAWKIALQDARTNTGYVGSDVMYDETAISSAPPPYTAYATPSPEVYGYGYGQYHGAYPTVGPQVFYASNGQAYDVPYQYPYHGPYGQPPANHVIIRERYRDNDGDLALGMLAGAATGMALGSLFWVF", "length": 224, "header": "sp|Q5F3S2-1|PKHB2_CHICK Isoform 1 of Pleckstrin homology domain-containing family B member 2 OS=Gallus gallus OX=9031 GN=PLEKHB2 PE=2 SV=1 CANONICAL=Q5F3S2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZWB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWB6/entry", "sequence": { "sequence": "MAFVKSGWLLRQSTILRRWKKNWFDLWSDGRLIFYDDQNRHDIEDKIHMRIHCINLRVGNECRDFQPPEGKQRDCLLQIVCRDGKTVNLCAESADDCLAWKIALQDARTNTGYVGSDVMYDETAISSAPPPYTAYATPSPEVYGYGYGQYHGAYPTVGPQVFYASNGQAYDVPYQYPYHGPYGQPPANHVIIRERYRDNDGDLALGMLAGAATGMALGSLFWAELSEHVRSEWLRSSSGLFLFSQKCE", "length": 248, "header": "tr|A0A8V0ZWB6-1|PKHB2_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family B member 2 OS=Gallus gallus OX=9031 GN=PLEKHB2 PE=2 SV=1 CANONICAL=Q5F3S2-1" }, "locus": { "chromosome": "9", "start_pos": 1862530, "end_pos": 1854592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058970.1", "url": "https://www.ensembl.org/id/ENSGALT00010058970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035935.1", "url": "https://www.ensembl.org/id/ENSGALP00010035935.1" } ] } }, { "isoform_ac": "Q5F3S2-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2/entry#Q5F3S2-1", "sequence": { "sequence": "MAFVKSGWLLRQSTILRRWKKNWFDLWSDGRLIFYDDQNRHDIEDKIHMRIHCINLRVGNECRDFQPPEGKQRDCLLQIVCRDGKTVNLCAESADDCLAWKIALQDARTNTGYVGSDVMYDETAISSAPPPYTAYATPSPEVYGYGYGQYHGAYPTVGPQVFYASNGQAYDVPYQYPYHGPYGQPPANHVIIRERYRDNDGDLALGMLAGAATGMALGSLFWVF", "length": 224, "header": "sp|Q5F3S2-1|PKHB2_CHICK Isoform 1 of Pleckstrin homology domain-containing family B member 2 OS=Gallus gallus OX=9031 GN=PLEKHB2 PE=2 SV=1 CANONICAL=Q5F3S2-1" }, "locus": { "chromosome": "9", "start_pos": 1862530, "end_pos": 1855231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058974.1", "url": "https://www.ensembl.org/id/ENSGALT00010058974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035939.1", "url": "https://www.ensembl.org/id/ENSGALP00010035939.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 137, "start_aa": "Thr", "end_pos": 137, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr137", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424758", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424758", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1WZZ6-1", "protein_name": "Pleckstrin homology domain containing B2", "gene_name": "PLEKHB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSVEDKVHMPVDCINIRTGHECRDIQPPDGKPKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSEVMYDETAVASSPPPYTAYAAPTPEQAYGYGPYSGAYPPGTQVVYAANGQAYAIPYQYPYAGLYGQQPANQVIIRERYRDNDSDLALGMLAGAATGMALGSLFWVF", "length": 222 }, "evidence": [ { "id": "Q5F3S2", "url": "https://omabrowser.org/oma/group/Q5F3S2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AN59-1", "protein_name": "Pleckstrin homology domain containing B2", "gene_name": "Plekhb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLRARAPAPAPAPERRARGARMLGRLPRLRSSAQVPVKTRLETESWNVVMVRSDFGRRCTPASFYLVPAFTCIMTSSYTQDFRGRNTRSASNLKPSGPHAEEMAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRTGHECRDIQPPDGKPRDCLLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAILSEETAVAASPPPYAAYATPTPEVYGYGPYSGAYPAGTQVVYAANGQAYAVPYQYPYAGVYGQQPANQVIIRERYRDSDSDLALGMLAGAATGMALGSLFWVF", "length": 324 }, "evidence": [ { "id": "Q5F3S2", "url": "https://omabrowser.org/oma/group/Q5F3S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H1S7-1", "protein_name": "Pleckstrin homology domain-containing family B member 2 isoform X1", "gene_name": "Plekhb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRMGHECRDIQPPDGKPRDCLLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAILSEETAVAASPPPYAAYAAPTPEVYGYGPYSGAYPAGTQVVYAANGQAYAVPYQYPYAGVYGQQPANQVIIRERYRDNDSDLALGMLAGAATGMALGSLFWVF", "length": 221 }, "evidence": [ { "id": "Q5F3S2", "url": "https://omabrowser.org/oma/group/Q5F3S2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q96CS7-1", "protein_name": "Pleckstrin homology domain-containing family B member 2", "gene_name": "PLEKHB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEQAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAGLYGQQPANQVIIRERYRDNDSDLALGMLAGAATGMALGSLFWVF", "length": 222 }, "evidence": [ { "id": "Q5F3S2", "url": "https://omabrowser.org/oma/group/Q5F3S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZC7-1", "protein_name": "Pleckstrin homology domain-containing family B member 2", "gene_name": "Plekhb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRTGHECRDIQPPDGKPRDCLLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAILSEETAVAASPPPYAAYATPTPEVYGYGPYSGAYPAGTQVVYAANGQAYAVPYQYPYAGVYGQQPANQVIIRERYRDNDSDLALGMLAGAATGMALGSLFWVF", "length": 221 }, "evidence": [ { "id": "Q5F3S2", "url": "https://omabrowser.org/oma/group/Q5F3S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "Q5F3S2", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3S2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 224, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3S2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3S2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F3S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3S2" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 2, "end_pos": 109, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 137, 156 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZKP7-1", "uniprot_ac": "Q5ZKP7", "uniprot_id": "S2536_CHICK", "mass": { "chemical_mass": 34557.0, "monoisotopic_mass": 34557.0 }, "refseq": { "ac": "NP_001007961", "name": "solute carrier family 25 member 36", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961" }, "gene_names": [ { "name": "SLC25A36", "type": "recommended", "evidence": [ { "id": "Q5ZKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ] }, { "name": "RCJMB04_9m7", "type": "synonym", "evidence": [ { "id": "Q5ZKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ] }, { "name": "SLC25A36", "type": "synonym", "evidence": [ { "id": "NP_001007961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 36", "type": "recommended", "evidence": [ { "id": "Q5ZKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 (pyrimidine nucleotide carrier), member 36", "type": "synonym", "evidence": [ { "id": "NP_001007961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961" } ] }, { "name": "solute carrier family 25 member 36", "type": "synonym", "evidence": [ { "id": "NP_001007961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720037.1, SRR13267658.354.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Dec 15, 2004 this sequence version replaced XP_422631.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961" } ] }, { "annotation": "Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7#function" }, { "database": "UniProtKB", "id": "Q96CQ1", "url": "https://www.uniprot.org/uniprotkb/Q96CQ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A36", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7", "locus": { "chromosome": "9", "start_pos": 6422430, "end_pos": 6452929, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025316", "url": "https://www.ensembl.org/id/ENSGALG00010025316" } ] } } ], "crossref": [ { "id": "Q5ZKP7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005283", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424817", "url": "https://www.ncbi.nlm.nih.gov/gene/424817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424817", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVMYEQM", "url": "https://omabrowser.org/oma/group/WVMYEQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX50", "url": "https://www.orthodb.org/?gene=A0A8V0ZX50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2C6", "url": "https://www.orthodb.org/?gene=A0A8V1A2C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKP7", "url": "https://www.orthodb.org/?gene=Q5ZKP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45829:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45829:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKP7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKP7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007961", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKP7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGASVNRVTRVSPGPLHCLKMILQKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNNIFNPDSTQVHMISAGVAGFTAITMTNPIWLVKTRLQLDARNRGEKRMSAFECVRKVYRSDGIKGFYRGMSASYAGISETVIHFVIYESIKRKLLEHKTASAMDSEDESAKEASDFVGMMMAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVREEGYGSLYRGLTTHLVRQIPNTAIMMSTYEVVVYLLDG", "length": 313, "header": "sp|Q5ZKP7-1|S2536_CHICK Isoform 1 of Solute carrier family 25 member 36 OS=Gallus gallus OX=9031 GN=SLC25A36 PE=2 SV=1 CANONICAL=Q5ZKP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZX50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX50/entry", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGASVNRVTRVSPGPLHCLKAIYFAAYSNCKEKLNNIFNPDSTQVHMISAGVAGFTAITMTNPIWLVKTRLQLDARNRGEKRMSAFECVRKVYRSDGIKGFYRGMSASYAGISETVIHFVIYESIKRKLLEHKTASAMDSEDESAKEASDFVGMMMAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVREEGYGSLYRGLTTHLVRQIPNTAIMMSTYEVVVYLLDG", "length": 287, "header": "tr|A0A8V0ZX50-1|S2536_CHICK Computationally mapped isoform of Solute carrier family 25 member 36 OS=Gallus gallus OX=9031 GN=SLC25A36 PE=2 SV=1 CANONICAL=Q5ZKP7-1" }, "locus": { "chromosome": "9", "start_pos": 6452808, "end_pos": 6426453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061809.1", "url": "https://www.ensembl.org/id/ENSGALT00010061809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038153.1", "url": "https://www.ensembl.org/id/ENSGALP00010038153.1" } ] } }, { "isoform_ac": "A0A8V1A2C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2C6/entry", "sequence": { "sequence": "SFARLNHVHLCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGAMYMILEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNNIFNPDSTQVHMISAGVAGFTAITMTNPIWLVKTRLQLDARNRGEKRMSAFECVRKVYRSDGIKGFYRGMSASYAGISETVIHFVIYESIKRKLLEHKTASAMDSEDESAKEASDFVGMMMAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVREEGYGSLYRGLTTHLVRQIPNTAIMMSTYEVVVYLLDG", "length": 292, "header": "tr|A0A8V1A2C6-1|S2536_CHICK Computationally mapped isoform of Solute carrier family 25 member 36 OS=Gallus gallus OX=9031 GN=SLC25A36 PE=2 SV=1 CANONICAL=Q5ZKP7-1" }, "locus": { "chromosome": "9", "start_pos": 6446476, "end_pos": 6426453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061803.1", "url": "https://www.ensembl.org/id/ENSGALT00010061803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038149.1", "url": "https://www.ensembl.org/id/ENSGALP00010038149.1" } ] } }, { "isoform_ac": "Q5ZKP7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7/entry#Q5ZKP7-1", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGASVNRVTRVSPGPLHCLKMILQKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNNIFNPDSTQVHMISAGVAGFTAITMTNPIWLVKTRLQLDARNRGEKRMSAFECVRKVYRSDGIKGFYRGMSASYAGISETVIHFVIYESIKRKLLEHKTASAMDSEDESAKEASDFVGMMMAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVREEGYGSLYRGLTTHLVRQIPNTAIMMSTYEVVVYLLDG", "length": 313, "header": "sp|Q5ZKP7-1|S2536_CHICK Isoform 1 of Solute carrier family 25 member 36 OS=Gallus gallus OX=9031 GN=SLC25A36 PE=2 SV=1 CANONICAL=Q5ZKP7-1" }, "locus": { "chromosome": "9", "start_pos": 6452808, "end_pos": 6426453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061808.1", "url": "https://www.ensembl.org/id/ENSGALT00010061808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038152.1", "url": "https://www.ensembl.org/id/ENSGALP00010038152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R7Y0-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMETEEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ACN9-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "Slc25a36", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEESVKEASDFVRMMLAAATSKTCATTVAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MU04-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLSTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGLFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGEKRMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKIASTMENEEESVKEVSDFVGMMLAAATSKTCATSIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P38127-1", "protein_name": "Mitochondrial pyrimidine nucleotide transporter RIM2", "gene_name": "RIM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPKKSIEEWEEDAIESVPYLASDEKGSNYKEATQIPLNLKQSEIENHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFNNGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQMKRLIKERSIEKFGYQAEGTKSTSEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLLS", "length": 377 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54Z02-1", "protein_name": "Mitochondrial substrate carrier family protein", "gene_name": "rimA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFPTFINYTTLSVPNSIQIPNNLNNINNIINIQNNNNNINNNNNNNNRKKRSKNALLHFIAGGIGGAAGVICTSPLEVIKTQLQAKNSNLLVKDKPRFVPTTAYSLYHLVKRDGKSGLWKGLGAHLLGVAPARAIHFSSYSFTKSIMNKLGYTDGPILWITSAVSSGAAVAITTSPIWLIKTRMQLQTSLKNFNEGTQYRGMFHCCLSILREEGPLGFYKGLGASLISVSESAFQFVLYEGFKNRIITEKRLKGYENPNELSTSEYLISAGIAKLIAAITTYPHEVVRTRLREQTKPGVKSKYTGVIQGLTLIAREEGIRGLFGGAGPHIIRVVPNSCIMFLTYELVLDIAHGVSLLFDTNHYRQ", "length": 365 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DG32-1", "protein_name": "Solute carrier family 25 member 36-A", "gene_name": "slc25a36a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTFYISEVQLSTVNGASVARMAPPGPLHCLKLILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSTSKEKLNNVFDPDSTQVHMLSAGLAGFTAITATNPIWLIKTRLQLDARNRGERRMSAFECVRRVYQSDGLRGFYRGMSASYAGISETVIHFVIYESIKRKLIEHKANSNMDDEDESVKDASDFVGMMLAAATSKTCATSIAYPHEVIRTRLREEGSKYRSFFQTLNMVFREEGYRALYRGLTTHLVRQIPNTAIMMCTYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7XA87-1", "protein_name": "Folate transporter 1, chloroplastic", "gene_name": "FOLT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAASWQWENATAGAVAGFATVAAMHSLDVVRTRFQVNDGRGSSLPTYKNTAHAVFTIARLEGLRGLYAGFFPAVIGSTVSWGLYFFFYGRAKQRYARGRDDEKLSPALHLASAAEAGALVCLCTNPIWLVKTRLQLQTPLHQTQPYSGLLDAFRTIVKEEGPRALYKGIVPGLVLVSHGAIQFTAYEELRKIIVDLKERRRKSESTDNLLNSADYAALGGSSKVAAVLLTYPFQVIRARLQQRPSTNGIPRYIDSLHVIRETARYEGLRGFYRGLTANLLKNVPASSITFIVYENVLKLLKQHPTTKD", "length": 308 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q922G0-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "Slc25a36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKAILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGVFDPDSTQVHMASAAMAGFTAITATNPIWLIKTRLQLDARTRGEKQMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEESVKEASDFVRMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CQ1-1", "protein_name": "Solute carrier family 25 member 36", "gene_name": "SLC25A36", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG", "length": 311 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQ37-1", "protein_name": "Mitochondrial carrier protein Rim2", "gene_name": "Rim2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQNTADTLIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQRRKLSTTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNLVGVAPSRAIYFCTYSQTKNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYNSKVQMTVRQCIERVYAQGGVAAFYKGITASYFGICETMVHFVIYEFIKSKLLEQRNQRHTDTKGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREEGNKYNSFWQTLHTVWKEEGRAGLYRGLATQLVRQIPNTAIMMATYEAVVYVLTRRFNNKSNEFYDF", "length": 365 }, "evidence": [ { "id": "Q5ZKP7", "url": "https://omabrowser.org/oma/group/Q5ZKP7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pyrimidine nucleotide transmembrane transporter activity", "id": "GO:0015218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015218", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyrimidine nucleotide import into mitochondrion", "id": "GO:1990519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990519", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKP7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q6RFL5-1", "uniprot_ac": "Q6RFL5", "uniprot_id": "BSH_CHICK", "mass": { "chemical_mass": 26452.0, "monoisotopic_mass": 26452.0 }, "refseq": { "ac": "NP_989843", "name": "brain-specific homeobox protein homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843" }, "gene_names": [ { "name": "BSX", "type": "recommended", "evidence": [ { "id": "Q6RFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ] }, { "name": "BSX", "type": "synonym", "evidence": [ { "id": "NP_989843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843" } ] } ], "protein_names": [ { "name": "Brain-specific homeobox protein homolog", "type": "recommended", "evidence": [ { "id": "Q6RFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5/entry#names_and_taxonomy" } ] }, { "name": "brain-specific homeobox protein homolog", "type": "synonym", "evidence": [ { "id": "NP_989843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843" } ] }, { "name": "brain-specific homeodomain protein", "type": "synonym", "evidence": [ { "id": "NP_989843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY500594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03579563, SAMN08016555 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY500594.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843" } ] }, { "annotation": "DNA binding protein that function as transcriptional activator. May play a role in the determination and function of cell types in the brain.", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BSX", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5", "locus": { "chromosome": "24", "start_pos": 3161916, "end_pos": 3136361, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025614", "url": "https://www.ensembl.org/id/ENSGALG00010025614" } ] } } ], "crossref": [ { "id": "Q6RFL5", "url": "https://alphafold.ebi.ac.uk/entry/Q6RFL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006515", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395183", "url": "https://www.ncbi.nlm.nih.gov/gene/395183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395183", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLPGKHC", "url": "https://omabrowser.org/oma/group/DLPGKHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3Q2", "url": "https://www.orthodb.org/?gene=A0A8V1A3Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A623", "url": "https://www.orthodb.org/?gene=A0A8V1A623", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q6RFL5", "url": "https://www.orthodb.org/?gene=Q6RFL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24333:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24333:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q6RFL5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q6RFL5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A623", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A623", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A623-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A623-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6RFL5-1", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLNFTSPVHPVPAPRPTSFFIEDILLHKPKPLREVPPEHFAGSLASRVPLLDYGYPLMPAPALLAPHPHPALHKPEHHHHHPYFLTTSGVPVPALFPHHAHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDDPIHEENREQSSPEPELPEPAAAEPRKGPPGPFLLQDPEDEVDILEEGDILAAPHRL", "length": 233, "header": "sp|Q6RFL5-1|BSH_CHICK Isoform 1 of Brain-specific homeobox protein homolog OS=Gallus gallus OX=9031 GN=BSX PE=2 SV=1 CANONICAL=Q6RFL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Q2/entry", "sequence": { "sequence": "MNLNFTSPVHPVPAPRPTSFFIEDILLHKPKPLREVPPEHFAGSLASRVPLLDYGYPLMPAPALLAPHPHPALHKPEHHHHHPYFLTTSGENLVPEPADETQKTAAEKPGRPHTRREPRAELPRARAPRAGRSRAPKGPPRPLLAAGPRGRGGHPGGGGYPRRPTPPLGALRAALRSPASLPQPRVLPGCRSLVSVRRGTKPPGSFRPFGCIPASPQA", "length": 218, "header": "tr|A0A8V1A3Q2-1|BSH_CHICK Computationally mapped isoform of Brain-specific homeobox protein homolog OS=Gallus gallus OX=9031 GN=BSX PE=2 SV=1 CANONICAL=Q6RFL5-1" }, "locus": { "chromosome": "24", "start_pos": 3155429, "end_pos": 3153599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062507.1", "url": "https://www.ensembl.org/id/ENSGALT00010062507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038652.1", "url": "https://www.ensembl.org/id/ENSGALP00010038652.1" } ] } }, { "isoform_ac": "A0A8V1A623-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A623/entry", "sequence": { "sequence": "MNLNFTSPVHPVPAPRPTSFFIEDILLHKPKPLREVPPEHFAGSLASRVPLLDYGYPLMPAPALLAPHPHPALHKPEHHHHHPYFLTTSGKCGALRGSPRVGREMGKGSSAPRRERVYTLGLRVPALPSPRLRQRRSEISTSRDLEPRDPRVSFSPFARLFRFELFLYLDREHYGSGMGPGFSFPPPPAVPGPCRTIPWPGRLSAPVRPPEPFPGPLPPKFLLGRPKFLSLWPLSPCPHFSRLFSRLPRFSWVHFVGF", "length": 258, "header": "tr|A0A8V1A623-1|BSH_CHICK Computationally mapped isoform of Brain-specific homeobox protein homolog OS=Gallus gallus OX=9031 GN=BSX PE=2 SV=1 CANONICAL=Q6RFL5-1" }, "locus": { "chromosome": "24", "start_pos": 3156115, "end_pos": 3155342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062509.1", "url": "https://www.ensembl.org/id/ENSGALT00010062509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038654.1", "url": "https://www.ensembl.org/id/ENSGALP00010038654.1" } ] } }, { "isoform_ac": "Q6RFL5-1", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5/entry#Q6RFL5-1", "sequence": { "sequence": "MNLNFTSPVHPVPAPRPTSFFIEDILLHKPKPLREVPPEHFAGSLASRVPLLDYGYPLMPAPALLAPHPHPALHKPEHHHHHPYFLTTSGVPVPALFPHHAHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDDPIHEENREQSSPEPELPEPAAAEPRKGPPGPFLLQDPEDEVDILEEGDILAAPHRL", "length": 233, "header": "sp|Q6RFL5-1|BSH_CHICK Isoform 1 of Brain-specific homeobox protein homolog OS=Gallus gallus OX=9031 GN=BSX PE=2 SV=1 CANONICAL=Q6RFL5-1" }, "locus": { "chromosome": "24", "start_pos": 3155277, "end_pos": 3153599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062501.1", "url": "https://www.ensembl.org/id/ENSGALT00010062501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038648.1", "url": "https://www.ensembl.org/id/ENSGALP00010038648.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A5F6-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "Bsx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHTHHPLHKGEHHHPYFLATSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPESPEGSPRAPEGAPADARLSLPAGAFVLTEPEDEVDIGDEGELSSGPHVL", "length": 232 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAF5-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "BSX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFTSTLASRVPLLDYGYPLMPTPTLLAPHPHHPLHKGDHHHPYFLTTSGVPVPALFPHPQHPELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAPDGPESPEGSPRGPEAAPAEARLGLPAGSFVLTEPEDEVDIGDEAELGSGPHVL", "length": 232 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S9Q4-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "BSX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLAPHPHHPLHKGDHHHPYFLTTSGVPVPALFPHPQHTELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAPDGPESPEGSPRGAEAAPAEARLGLPAGPFVLTEPEDEVDIGDEGELGSGPHVL", "length": 232 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3C1V8-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "BSX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLAPHAHHPLHKGDHHHPYFLTTSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAPDGPESPEGSPRGSEAATAAEARLSLPAGPFVLTEPEDEVDIGDEGELGSGPHVL", "length": 233 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6R3Q6-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "bsx", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNLNYTSPVPQMPTQRSTSFFIEDILLHKPKPLREVFPSPFSNSIASRMPLLEYGYPLMPTPILAPHPHHPLHKPEHHPYFFTSGMQMPALFQHHPELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKTQDDQKTPNDVDRSLENTSESEMHEKNTDGKNGMSPDRYTLDDNEDDVDIEDDICSPEHLL", "length": 227 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q810B3-1", "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "Bsx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHAHHPLHKGDHHHPYFLTTSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPESPEGSPRAPEGAPADARLSLPAGAFVLTEPEDEVDIGDEGELSSGPHVL", "length": 232 }, "evidence": [ { "id": "Q6RFL5", "url": "https://omabrowser.org/oma/group/Q6RFL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "eating behavior", "id": "GO:0042755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042755", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "Q6RFL5", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q6RFL5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 233, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q6RFL5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q6RFL5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q6RFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6RFL5" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000255", "start_pos": 110, "end_pos": 170, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJZ4-1", "uniprot_ac": "Q5ZJZ4", "uniprot_id": "S35G2_CHICK", "mass": { "chemical_mass": 45740.0, "monoisotopic_mass": 45740.0 }, "refseq": { "ac": "NP_001026470", "name": "solute carrier family 35 member G2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" }, "gene_names": [ { "name": "SLC35G2", "type": "recommended", "evidence": [ { "id": "Q5ZJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ] }, { "name": "RCJMB04_14e7", "type": "synonym", "evidence": [ { "id": "Q5ZJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ] }, { "name": "SLC35G2", "type": "synonym", "evidence": [ { "id": "NP_001026470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" } ] }, { "name": "TMEM22", "type": "synonym", "evidence": [ { "id": "NP_001026470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" }, { "id": "Q5ZJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member G2", "type": "recommended", "evidence": [ { "id": "Q5ZJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 22", "type": "synonym", "evidence": [ { "id": "Q5ZJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member G2", "type": "synonym", "evidence": [ { "id": "NP_001026470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" } ] }, { "name": "transmembrane protein 22", "type": "synonym", "evidence": [ { "id": "NP_001026470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720290.1, HAEK01078336.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720290.1. On Aug 8, 2005 this sequence version replaced XP_422560.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35G2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4", "locus": { "chromosome": "9", "start_pos": 488523, "end_pos": 478473, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025427", "url": "https://www.ensembl.org/id/ENSGALG00010025427" } ] } } ], "crossref": [ { "id": "Q5ZJZ4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "424738", "url": "https://www.ncbi.nlm.nih.gov/gene/424738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424738", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424738", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYHHEPP", "url": "https://omabrowser.org/oma/group/CYHHEPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7N5", "url": "https://www.orthodb.org/?gene=A0A8V1A7N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7P1", "url": "https://www.orthodb.org/?gene=A0A8V1A7P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJZ4", "url": "https://www.orthodb.org/?gene=Q5ZJZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22911:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22911:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJZ4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJZ4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7P1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJZ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSSSQKYLVKKRVKIHPNTVTVKYTSHYPQPGEEGYEDGNEDTGVFMEDSPKTRLLNAGKKRERTFFGTIDTQLQPAQLPKPREMGHFQNFPEGNILQSRKMWIVLFGSAVAHGCVALITRLISDRSKVPSLELIFIRSILQVLSVTAVCYYHEPPFGPKGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTIMWRATTTVFSAILAFLLVDEGMASVDIVTVVGSVFGVCLVMIPNIVKEENSLLSTWKEAFGYTMTVMAGLTTALSMIVYRSIKDNISMWTALFTFSWTGTVWGASTMFLLQEPIVPLDGETWSYLLAICLCSTAAFLGVYYALSKFHPALVSTVQHLEIVIAMVLQLVVLRILPGTYDLVGGAVILVSVVFLACHKLSWKNLGRQDYQEIVDSSIK", "length": 411, "header": "sp|Q5ZJZ4-1|S35G2_CHICK Isoform 1 of Solute carrier family 35 member G2 OS=Gallus gallus OX=9031 GN=SLC35G2 PE=2 SV=1 CANONICAL=Q5ZJZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N5/entry", "sequence": { "sequence": "MAHSHGFLPTLYVDKDVDDREVFSPSGLESNLSRAGHSSKEMDSSSQKYLVKKRVKIHPNTVTVKYTSHYPQPGEEGYEDGNEDTGVFMEDSPKTRLLNAGKKRERTFFGTIDTQLQPAQLPKPREMGHFQNFPEGNILQSRKMWIVLFGSAVAHGCVALITRLISDRSKVPSLELIFIRSILQVLSVTAVCYYHEPPFGPKGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTIMWRATTTVFSAILAFLLVDEGMASVDIVTVVGSVFGVCLVMIPNIVKEENSLLSTWKEAFGYTMTVMAGLTTALSMIVYRSIKDNISMWTALFTFSWTGTVWGASTMFLLQEPIVPLDGETWSYLLAICLCSTAAFLGVYYALSKFHPALVSTVQHLEIVIAMVLQLVVLRILPGTYDLVGGAVILVSVVFLACHKLSWKNLGRQDYQEIVDSSIK", "length": 452, "header": "tr|A0A8V1A7N5-1|S35G2_CHICK Computationally mapped isoform of Solute carrier family 35 member G2 OS=Gallus gallus OX=9031 GN=SLC35G2 PE=2 SV=1 CANONICAL=Q5ZJZ4-1" }, "locus": { "chromosome": "9", "start_pos": 484072, "end_pos": 479781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062069.1", "url": "https://www.ensembl.org/id/ENSGALT00010062069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038350.1", "url": "https://www.ensembl.org/id/ENSGALP00010038350.1" } ] } }, { "isoform_ac": "A0A8V1A7P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P1/entry", "sequence": { "sequence": "MRADRLAGKTKVPRFRSVHPFSSVTETSAVAVPWHVAARRAPRVPPRSAVSQPSPLSPRCAHGWELRAGSCRQPEGQSGASAGKGQREVLLRPVGKAALRGVGAPCAEAVRQRHRPSPVTGLRRYVDKDVDDREVFSPSGLESNLSRAGHSSKEMDSSSQKYLVKKRVKIHPNTVTVKYTSHYPQPGEEGYEDGNEDTGVFMEDSPKTRLLNAGKKRERTFFGTIDTQLQPAQLPKPREMGHFQNFPEGNILQSRKMWIVLFGSAVAHGCVALITRLISDRSKVPSLELIFIRSILQVLSVTAVCYYHEPPFGPKGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTIMWRATTTVFSAILAFLLVDEGMASVDIVTVVGSVFGVCLVMIPNIVKEENSLLSTWKEAFGYTMTVMAGLTTALSMIVYRSIKDNISMWTALFTFSWTGTVWGASTMFLLQEPIVPLDGETWSYLLAICLCSTAAFLGVYYALSKFHPALVSTVQHLEIVIAMVLQLVVLRILPGTYDLVGGAVILVSVVFLACHKLSWKNLGRQDYQEIVDSSIK", "length": 565, "header": "tr|A0A8V1A7P1-1|S35G2_CHICK Computationally mapped isoform of Solute carrier family 35 member G2 OS=Gallus gallus OX=9031 GN=SLC35G2 PE=2 SV=1 CANONICAL=Q5ZJZ4-1" }, "locus": { "chromosome": "9", "start_pos": 484072, "end_pos": 479032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062074.1", "url": "https://www.ensembl.org/id/ENSGALT00010062074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038355.1", "url": "https://www.ensembl.org/id/ENSGALP00010038355.1" } ] } }, { "isoform_ac": "Q5ZJZ4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4/entry#Q5ZJZ4-1", "sequence": { "sequence": "MDSSSQKYLVKKRVKIHPNTVTVKYTSHYPQPGEEGYEDGNEDTGVFMEDSPKTRLLNAGKKRERTFFGTIDTQLQPAQLPKPREMGHFQNFPEGNILQSRKMWIVLFGSAVAHGCVALITRLISDRSKVPSLELIFIRSILQVLSVTAVCYYHEPPFGPKGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTIMWRATTTVFSAILAFLLVDEGMASVDIVTVVGSVFGVCLVMIPNIVKEENSLLSTWKEAFGYTMTVMAGLTTALSMIVYRSIKDNISMWTALFTFSWTGTVWGASTMFLLQEPIVPLDGETWSYLLAICLCSTAAFLGVYYALSKFHPALVSTVQHLEIVIAMVLQLVVLRILPGTYDLVGGAVILVSVVFLACHKLSWKNLGRQDYQEIVDSSIK", "length": 411, "header": "sp|Q5ZJZ4-1|S35G2_CHICK Isoform 1 of Solute carrier family 35 member G2 OS=Gallus gallus OX=9031 GN=SLC35G2 PE=2 SV=1 CANONICAL=Q5ZJZ4-1" }, "locus": { "chromosome": "9", "start_pos": 484072, "end_pos": 482840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062078.1", "url": "https://www.ensembl.org/id/ENSGALT00010062078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038359.1", "url": "https://www.ensembl.org/id/ENSGALP00010038359.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424738", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424738", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YVE8-1", "protein_name": "Solute carrier family 35 member G2", "gene_name": "Slc35g2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSPSKKYPIKKRVKIHPNTVMVKYTSHYPQPGDDGYEEINEDYGRFMEENPKKSLLSEMRRKGRTLFGTMDTQPSSSEDPRASGMGQFQSFAEKNIFQSRKMWLVLFGSALAHGCVALITRLISDRSKVPSLELIFIRSVLQVLSVIVVCYYQEAPFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIADEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIREKISMWTALFTFGWTGTIWGLSTMFVLQEPIIPLDGATWSYLIAICLCSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSVYDVFGGVIIMISVFVLAGYKLYWRNVRREDYQEILDSPIK", "length": 412 }, "evidence": [ { "id": "Q5ZJZ4", "url": "https://omabrowser.org/oma/group/Q5ZJZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3HEY7-1", "protein_name": "Solute carrier family 35 member G2", "gene_name": "Slc35g2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTSPSKQSPVKKRVKIHPNTVMVKYTSHYPQPGDDGYEEINEDYGKFMEENPKKSLLSEIKRKGRTLFGTMDTQPPLTEDLRASGIAQFHSFAEKNIFQSRKMWIVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVLQVLSVLVVCYYQEAPFGPSGYRLRLFFYGICNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIVDEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIREKISMWTALFTFGWTGTIWGVSTMFVLQEPIIPLDGETWSYLIAICICSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSVYDVFGGVIIMISVFVLAGYKLYWRNVRREDYQEILDSPIK", "length": 412 }, "evidence": [ { "id": "Q5ZJZ4", "url": "https://omabrowser.org/oma/group/Q5ZJZ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LKR9-1", "protein_name": "Solute carrier family 35 member G2", "gene_name": "SLC35G2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTSPSKKYPVKKRVKIHPNTVMVKYTSHYPQPGDNGYEEINEDYGNFMEENPKKGLLSEMKRKGRTFFGTMDTRPPPTEDPVINETGQLQSFAEKNIFQSRKMWIVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVLQVLSVLVVCYYQEAPFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIVDEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIKEKISMWTALFTFGWTGTVWGVSTMFVLQEPIIPLDGETWSYLIAICVCSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSVYDVFGGVIIMISVFVLAGYKLYWRNLRRQDYQEILDSPIK", "length": 412 }, "evidence": [ { "id": "Q5ZJZ4", "url": "https://omabrowser.org/oma/group/Q5ZJZ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5M7A3-1", "protein_name": "Solute carrier family 35 member G2", "gene_name": "Slc35g2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSPSKKYPIKKRVKIHPNTVMVKYTSHYPQPGEDGYEEINEDYGRFMEENPKKSLLSEMRRKGRTLFGTMDTQPPRSEDPRASSRGQFQSFAEKNIFQSRKMWLVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVLQVLSVIVVCYYQEAPFGPSGYRLRLFLYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAVLAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIADEDNSLLNVWKEAFGYTMTVMAGLTTALSMIVYRSIREKISMWTALFTFGWTGTIWGLSTMFVLQEPIIPLDGETWSYLIAICICSTVAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSVYDVFGGVIIMISVFVLAGYKLYWRNVRREDYQEILDSPIK", "length": 412 }, "evidence": [ { "id": "Q5ZJZ4", "url": "https://omabrowser.org/oma/group/Q5ZJZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TBE7-1", "protein_name": "Solute carrier family 35 member G2", "gene_name": "SLC35G2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSPSRKYPVKKRVKIHPNTVMVKYTSHYPQPGDDGYEEINEGYGNFMEENPKKGLLSEMKKKGRAFFGTMDTLPPPTEDPMINEIGQFQSFAEKNIFQSRKMWIVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVFQVLSVLVVCYYQEAPFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIVDEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIKEKISMWTALFTFGWTGTIWGISTMFILQEPIIPLDGETWSYLIAICVCSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSIYDVFGGVIIMISVFVLAGYKLYWRNLRKQDYQEILDSPIK", "length": 412 }, "evidence": [ { "id": "Q5ZJZ4", "url": "https://omabrowser.org/oma/group/Q5ZJZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJZ4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJZ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 411, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJZ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJZ4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZJ39-1", "uniprot_ac": "Q5ZJ39", "uniprot_id": "DENR_CHICK", "mass": { "chemical_mass": 22158.0, "monoisotopic_mass": 22158.0 }, "refseq": { "ac": "NP_001072973", "name": "density-regulated protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973" }, "gene_names": [ { "name": "DENR", "type": "recommended", "evidence": [ { "id": "Q5ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ] }, { "name": "DENR", "type": "synonym", "evidence": [ { "id": "NP_001072973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973" } ] }, { "name": "RCJMB04_20p1", "type": "synonym", "evidence": [ { "id": "Q5ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ] } ], "protein_names": [ { "name": "Density-regulated protein", "type": "recommended", "evidence": [ { "id": "Q5ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39/entry#names_and_taxonomy" } ] }, { "name": "DRP", "type": "synonym", "evidence": [ { "id": "NP_001072973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973" }, { "id": "Q5ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39/entry#names_and_taxonomy" } ] }, { "name": "density-regulated protein", "type": "synonym", "evidence": [ { "id": "NP_001072973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01194995.1, AJ449131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06143078, SAMN08016552 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Dec 9, 2006 this sequence version replaced XP_001233651.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001072973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973" } ] }, { "annotation": "May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENR", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39", "locus": { "chromosome": "15", "start_pos": 5285462, "end_pos": 5291588, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025026", "url": "https://www.ensembl.org/id/ENSGALG00010025026" } ] } } ], "crossref": [ { "id": "Q5ZJ39", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJ39", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003795", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003795", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11607", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11607", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771794", "url": "https://www.ncbi.nlm.nih.gov/gene/771794", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771794", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771794", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVFEIDM", "url": "https://omabrowser.org/oma/group/EVFEIDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8V4", "url": "https://www.orthodb.org/?gene=A0A8V1A8V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJ39", "url": "https://www.orthodb.org/?gene=Q5ZJ39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12789:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12789:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJ39", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJ39", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001072973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ39-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDVAEPVVPDCRGDIRSGARSDADYPLRVLYCGVCSLPTEYCEYMPDVTKCRQWLEKNFPDEFAKLTVENSPKQEAGVGEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198, "header": "sp|Q5ZJ39-1|DENR_CHICK Isoform 1 of Density-regulated protein OS=Gallus gallus OX=9031 GN=DENR PE=2 SV=1 CANONICAL=Q5ZJ39-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8V4/entry", "sequence": { "sequence": "MCASKPPLRAFDMATDVAEPVVPDCRGDIRSGARSDADYPLRVLYCGVCSLPTEYCEYMPDVTKCRQWLEKNFPDEFAKLTVENSPKQEAGVGEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 210, "header": "tr|A0A8V1A8V4-1|DENR_CHICK Computationally mapped isoform of Density-regulated protein OS=Gallus gallus OX=9031 GN=DENR PE=2 SV=1 CANONICAL=Q5ZJ39-1" }, "locus": { "chromosome": "15", "start_pos": 5291127, "end_pos": 5285694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061100.1", "url": "https://www.ensembl.org/id/ENSGALT00010061100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037803.1", "url": "https://www.ensembl.org/id/ENSGALP00010037803.1" } ] } }, { "isoform_ac": "Q5ZJ39-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39/entry#Q5ZJ39-1", "sequence": { "sequence": "MATDVAEPVVPDCRGDIRSGARSDADYPLRVLYCGVCSLPTEYCEYMPDVTKCRQWLEKNFPDEFAKLTVENSPKQEAGVGEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198, "header": "sp|Q5ZJ39-1|DENR_CHICK Isoform 1 of Density-regulated protein OS=Gallus gallus OX=9031 GN=DENR PE=2 SV=1 CANONICAL=Q5ZJ39-1" }, "locus": { "chromosome": "15", "start_pos": 5290560, "end_pos": 5285694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061105.1", "url": "https://www.ensembl.org/id/ENSGALT00010061105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037806.1", "url": "https://www.ensembl.org/id/ENSGALP00010037806.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:771794", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771794", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UG52-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAADISESGGHDCKGDLKSNTKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGITEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N3T0-1", "protein_name": "Density-regulated protein", "gene_name": "Denr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATDVSESSGADCKGDTRNSAKLDSEYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKPETGVSESQGTLGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZU54-1", "protein_name": "Density-regulated protein", "gene_name": "Denr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATDISESSGADTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGISEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 194 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43583-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADISESSGADCKGDPRNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47089-1", "protein_name": "Translation machinery-associated protein 22", "gene_name": "TMA22", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLREVIYCGICSYPPEYCEFSGKLKRCKVWLSENHADLYAKLYGTDDNTQEVEAVTNKLAESSIGEAREEKLEKDLLKIQKKQENREQRELAKKLSSKVIIKREARTKRKFIVAISGLEVFDIDMKKLAKTFASRFATGCSVSKNAEKKEEVVIQGDVMDEVETYIHSLLEEKGLKDVKVETIDAKKKKKPAAEGAAK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2HJ47-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAADISESGGHDCRGDQRSNTKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54WG0-1", "protein_name": "Density-regulated protein homolog", "gene_name": "denr", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDTESSTPSQPIVVVEYCKICSLPTEYCEYGPSAKQCLKENGPHPNNNKNTASGKDSSNTTATTTTTDTTTTTTTSTENTEEKLKDLKIVDDSKEVSHVDAGKSESKEATGEEKEKEKVSKKKKEVKPQIIIEVNQRNKRKHVTKITGLELYGIKLSDAAKVMAKKFSCGCSVVKSISNPNSEDIDIQGDFGEELVDLIEEKYPTVPLSEIYFLEDKKKVKAR", "length": 224 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CQJ6-1", "protein_name": "Density-regulated protein", "gene_name": "Denr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATDISESSGADCKGDTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "Q5ZJ39", "url": "https://omabrowser.org/oma/group/Q5ZJ39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" }, { "name": "IRES-dependent viral translational initiation", "id": "GO:0075522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075522", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ39", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJ39-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 198, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJ39-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJ39" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ39" }, { "id": "PRU00200", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUI1", "eco_id": "ECO_0000255", "start_pos": 115, "end_pos": 182, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZLT5-1", "uniprot_ac": "Q5ZLT5", "uniprot_id": "PKHJ1_CHICK", "mass": { "chemical_mass": 17778.0, "monoisotopic_mass": 17778.0 }, "refseq": { "ac": "NP_001026674", "name": "pleckstrin homology domain-containing family J member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674" }, "gene_names": [ { "name": "PLEKHJ1", "type": "recommended", "evidence": [ { "id": "Q5ZLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ] }, { "name": "PLEKHJ1", "type": "synonym", "evidence": [ { "id": "NP_001026674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674" } ] }, { "name": "RCJMB04_4o19", "type": "synonym", "evidence": [ { "id": "Q5ZLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family J member 1", "type": "recommended", "evidence": [ { "id": "Q5ZLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5/entry#names_and_taxonomy" } ] }, { "name": "PH domain-containing family J member 1", "type": "synonym", "evidence": [ { "id": "NP_001026674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674" }, { "id": "Q5ZLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family J member 1", "type": "synonym", "evidence": [ { "id": "NP_001026674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719649.1, SRR13267652.2052.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000375.1. On Aug 8, 2005 this sequence version replaced XP_425884.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5", "locus": { "chromosome": "28", "start_pos": 2461721, "end_pos": 2454597, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027885", "url": "https://www.ensembl.org/id/ENSGALG00010027885" } ] } } ], "crossref": [ { "id": "Q5ZLT5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000835", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000835", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13258", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13258", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428324", "url": "https://www.ncbi.nlm.nih.gov/gene/428324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428324", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEQCKEW", "url": "https://omabrowser.org/oma/group/EEQCKEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAV6", "url": "https://www.orthodb.org/?gene=A0A8V1AAV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLT5", "url": "https://www.orthodb.org/?gene=Q5ZLT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22902:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22902:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLT5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLT5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLT5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRYNERELLSLSRQPAEKAAEILMRVPKKGSVLKKRLVKLVVNFLFYFRTDEAEPIGALLLEHCRITKEEENVFSISFIEEPERKYCFECDSEEQCQEWIEALKRASYEFMRRSLIFYRNEIQKMTGKDPLEQFGISEEARFQLASHKQ", "length": 149, "header": "sp|Q5ZLT5-1|PKHJ1_CHICK Isoform 1 of Pleckstrin homology domain-containing family J member 1 OS=Gallus gallus OX=9031 GN=PLEKHJ1 PE=2 SV=1 CANONICAL=Q5ZLT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV6/entry", "sequence": { "sequence": "MRYNERELLSLSRQPAEKAAEILMRVPKKGSVLKKRLVKLVVNFLFYFRTDEAEVRILLLLTQLCQDLTYTFSLSLVGFIEEPERKYCFECDSEEQCQEWIEALKRASYEFMRRSLIFYRNEIQKMTGKDPLEQFGISEEARFQLASHKQ", "length": 150, "header": "tr|A0A8V1AAV6-1|PKHJ1_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family J member 1 OS=Gallus gallus OX=9031 GN=PLEKHJ1 PE=2 SV=1 CANONICAL=Q5ZLT5-1" }, "locus": { "chromosome": "28", "start_pos": 2459145, "end_pos": 2454674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067586.1", "url": "https://www.ensembl.org/id/ENSGALT00010067586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041329.1", "url": "https://www.ensembl.org/id/ENSGALP00010041329.1" } ] } }, { "isoform_ac": "Q5ZLT5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5/entry#Q5ZLT5-1", "sequence": { "sequence": "MRYNERELLSLSRQPAEKAAEILMRVPKKGSVLKKRLVKLVVNFLFYFRTDEAEPIGALLLEHCRITKEEENVFSISFIEEPERKYCFECDSEEQCQEWIEALKRASYEFMRRSLIFYRNEIQKMTGKDPLEQFGISEEARFQLASHKQ", "length": 149, "header": "sp|Q5ZLT5-1|PKHJ1_CHICK Isoform 1 of Pleckstrin homology domain-containing family J member 1 OS=Gallus gallus OX=9031 GN=PLEKHJ1 PE=2 SV=1 CANONICAL=Q5ZLT5-1" }, "locus": { "chromosome": "28", "start_pos": 2459145, "end_pos": 2454674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067587.1", "url": "https://www.ensembl.org/id/ENSGALT00010067587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041330.1", "url": "https://www.ensembl.org/id/ENSGALP00010041330.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428324", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S8I9-1", "protein_name": "Pleckstrin homology domain-containing family J member 1", "gene_name": "PLEKHJ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRFNEKELQALSRQPAEMAAELGMRGPKKGSVVKRRLVKLVVNFLFYFRTDEAEPVGALLLEHCRVTQEEPSGFSISFLEDPERKYHFECCSEEQCQEWMAALRRASYEFMRRSLVFYRNEIQKVTGKDPLEQFGISEEARFQLSGLKA", "length": 149 }, "evidence": [ { "id": "Q5ZLT5", "url": "https://omabrowser.org/oma/group/Q5ZLT5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZCI3-1", "protein_name": "Pleckstrin homology domain-containing family J member 1", "gene_name": "PLEKHJ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRYNDKELQALSRQPAEMAAELGMRGPKKGSVVKRRLVKLVVNFLFYFRTDEAEPIGALLLEHCRVIHEEPNSFSISFLEDPERKYHFECCSEEQCQQWMAALRQASYEFMRRSLIFYRNEIQKMTGKDPLEQYGISEEARFQLSGLKA", "length": 149 }, "evidence": [ { "id": "Q5ZLT5", "url": "https://omabrowser.org/oma/group/Q5ZLT5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D240-1", "protein_name": "Pleckstrin homology domain-containing family J member 1", "gene_name": "Plekhj1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRYNEKELQALSRQPAEMAAELGMRGPKKGSVAKRRLVKLVVNFLFYFRPDEAEPLGALLLERCRVAQEEPGGFSISFVEDLSRKYHFECCSQEQCQDWMEALQRASYEYMRQSLIFYRNEIRKMTGKDPLEQFGISEEARFQLNSLPKDGRTTCIGSQLNVLD", "length": 164 }, "evidence": [ { "id": "Q5ZLT5", "url": "https://omabrowser.org/oma/group/Q5ZLT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NW61-1", "protein_name": "Pleckstrin homology domain-containing family J member 1", "gene_name": "PLEKHJ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRYNEKELQALSRQPAEMAAELGMRGPKKGSVLKRRLVKLVVNFLFYFRTDEAEPVGALLLERCRVVREEPGTFSISFIEDPERKYHFECSSEEQCQEWMEALRRASYEFMRRSLIFYRNEIRKVTGKDPLEQFGISEEARFQLSGLQA", "length": 149 }, "evidence": [ { "id": "Q5ZLT5", "url": "https://omabrowser.org/oma/group/Q5ZLT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" } ], "pmid": "" } ] }, { "name": "Biological 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"pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLT5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLT5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZLT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT5" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 15, "end_pos": 108, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5ZMC0-1", "uniprot_ac": "Q5ZMC0", "uniprot_id": "EDF1_CHICK", "mass": { "chemical_mass": 16364.0, "monoisotopic_mass": 16364.0 }, "refseq": { "ac": "NP_001006203", "name": "endothelial differentiation-related factor 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203" }, "gene_names": [ { "name": "EDF1", "type": "recommended", "evidence": [ { "id": "Q5ZMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0" } ] }, { "name": "EDF1", "type": "synonym", "evidence": [ { "id": "NP_001006203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203" } ] }, { "name": "RCJMB04_2j2", "type": "synonym", "evidence": [ { "id": "Q5ZMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0" } ] } ], "protein_names": [ { "name": "Endothelial differentiation-related factor 1 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0/entry#names_and_taxonomy" } ] }, { "name": "EDF-1", "type": "synonym", "evidence": [ { "id": "NP_001006203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203" }, { "id": "Q5ZMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0/entry#names_and_taxonomy" } ] }, { "name": "endothelial differentiation-related factor 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719464.1, HAEK01000096.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Jan 13, 2005 this sequence version replaced XP_415559.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203" } ] }, { "annotation": "Probable transcriptional coactivator.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMC0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMC0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EDF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0", "locus": { "chromosome": "17", "start_pos": 1229365, "end_pos": 1225878, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028462", "url": "https://www.ensembl.org/id/ENSGALG00010028462" } ] } } ], "crossref": [ { "id": "Q5ZMC0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038003", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038003", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00093", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417286", "url": "https://www.ncbi.nlm.nih.gov/gene/417286", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417286", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417286", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKNKSCK", "url": "https://omabrowser.org/oma/group/GKNKSCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIP8", "url": "https://www.orthodb.org/?gene=A0A8V1AIP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMC0", "url": "https://www.orthodb.org/?gene=Q5ZMC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10245:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10245:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMC0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMC0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMC0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMC0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESDWDTVTVLRKKGPSAAQAKSKQAVLAAQRRGEDVETSKKWAAGQNKQHFITKNTAKLDRETEELHHDRVPLEVGKVIQQGRQSKGMTQKDLATKINEKPQVIADYESGRAIPNNQVMGKIERAIGLKLRGKDIGKPLETGPKGK", "length": 148, "header": "sp|Q5ZMC0-1|EDF1_CHICK Isoform 1 of Endothelial differentiation-related factor 1 homolog OS=Gallus gallus OX=9031 GN=EDF1 PE=2 SV=1 CANONICAL=Q5ZMC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP8/entry", "sequence": { "sequence": "AQTYRRARRPVGGRQGPPRAQSAGGAAGSAGAAPRRGRGEQRRRRHGGERLGHGDGAAQEGPQRGPGQVQAGAAGQNKQHFITKNTAKLDRETEELHHDRVPLEVGKVIQQGRQSKGMTQKDLATKINEKPQVIADYESGRAIPNNQVMGKIERAIGLKLRGKDIGKPLETGPKGK", "length": 176, "header": "tr|A0A8V1AIP8-1|EDF1_CHICK Computationally mapped isoform of Endothelial differentiation-related factor 1 homolog OS=Gallus gallus OX=9031 GN=EDF1 PE=2 SV=1 CANONICAL=Q5ZMC0-1" }, "locus": { "chromosome": "17", "start_pos": 1228832, "end_pos": 1226077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068925.1", "url": "https://www.ensembl.org/id/ENSGALT00010068925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042367.1", "url": "https://www.ensembl.org/id/ENSGALP00010042367.1" } ] } }, { "isoform_ac": "Q5ZMC0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0/entry#Q5ZMC0-1", "sequence": { "sequence": "MAESDWDTVTVLRKKGPSAAQAKSKQAVLAAQRRGEDVETSKKWAAGQNKQHFITKNTAKLDRETEELHHDRVPLEVGKVIQQGRQSKGMTQKDLATKINEKPQVIADYESGRAIPNNQVMGKIERAIGLKLRGKDIGKPLETGPKGK", "length": 148, "header": "sp|Q5ZMC0-1|EDF1_CHICK Isoform 1 of Endothelial differentiation-related factor 1 homolog OS=Gallus gallus OX=9031 GN=EDF1 PE=2 SV=1 CANONICAL=Q5ZMC0-1" }, "locus": { "chromosome": "17", "start_pos": 1228832, "end_pos": 1226213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068924.1", "url": "https://www.ensembl.org/id/ENSGALT00010068924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042366.1", "url": "https://www.ensembl.org/id/ENSGALP00010042366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMC0", "url": "https://www.uniprot.org/uniprotkb/Q5ZMC0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417286", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417286", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M9PFR6-1", "protein_name": "Multiprotein bridging factor 1, isoform E", "gene_name": "mbf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDWDSVTVLRKKAPKSSTLKTESAVNQARRQGVAVDTQQKYGAGTNKQHVTTKNTAKLDRETEELRHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLRGKERGQPIAPPGKKXNDAAASAASGAPHTVTSGRSARQQNHQHTDSGGWSTVSGRRK", "length": 188 }, "evidence": [ { "id": "Q5ZMC0", "url": "https://omabrowser.org/oma/group/Q5ZMC0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O14467-1", "protein_name": "Multiprotein-bridging factor 1", "gene_name": "MBF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDWDTNTIIGSRARAGGSGPRANVARSQGQINAARRQGLVVSVDKKYGSTNTRGDNEGQRLTKVDRETDIVKPKKLDPNVGRAISRARTDKKMSQKDLATKINEKPTVVNDYEAARAIPNQQVLSKLERALGVKLRGNNIGSPLGAPKKK", "length": 151 }, "evidence": [ { "id": "Q5ZMC0", "url": "https://omabrowser.org/oma/group/Q5ZMC0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "O60869-1", "protein_name": "Endothelial differentiation-related factor 1", "gene_name": "EDF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK", "length": 148 }, "evidence": [ { "id": "Q5ZMC0", "url": "https://omabrowser.org/oma/group/Q5ZMC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P69736-1", "protein_name": "Endothelial differentiation-related factor 1", "gene_name": "Edf1", "tax_id": 10116, 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P80897-1", "uniprot_ac": "P80897", "uniprot_id": "RPN2_CHICK", "mass": { "chemical_mass": 3927.0, "monoisotopic_mass": 3927.0 }, "refseq": {}, "gene_names": [ { "name": "RPN2", "type": "recommended", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897" } ] } ], "protein_names": [ { "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "type": "recommended", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#names_and_taxonomy" } ] }, { "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 65-II kDa subunit", "type": "synonym", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#names_and_taxonomy" } ] }, { "name": "RPN-II", "type": "synonym", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#names_and_taxonomy" } ] }, { "name": "Ribophorin II", "type": "synonym", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#names_and_taxonomy" } ] }, { "name": "Ribophorin-2", "type": "synonym", "evidence": [ { "id": "P80897", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P80897", "url": "https://www.uniprot.org/uniprotkb/P80897#function" }, { "database": "UniProtKB", "id": "F1PCT7", "url": "https://www.uniprot.org/uniprotkb/F1PCT7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P80897", "url": "https://www.uniprot.org/uniprotkb/P80897" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPN2", "url": "https://www.uniprot.org/uniprotkb/P80897", "locus": { "chromosome": "20", "start_pos": 5398783, "end_pos": 5350853, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022438", "url": "https://www.ensembl.org/id/ENSGALG00010022438" } ] } } ], "crossref": [ { "id": "P80897", "url": "https://alphafold.ebi.ac.uk/entry/P80897", "database": "AlphaFoldDB", "categories": [] }, { "id": "P80897", "url": "https://www.orthodb.org/?gene=P80897", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P80897", "url": "https://www.uniprot.org/uniprotkb/P80897", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P80897-1", "url": "https://www.uniprot.org/uniprotkb/P80897-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "NAIFSKKNFETLSEAFSVFQTLKYLAILGGVTFLAG", "length": 36, "header": "sp|P80897-1|RPN2_CHICK Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Gallus gallus OX=9031 GN=RPN2 PE=1 SV=1 CANONICAL=P80897-1" }, "isoforms": [ { "isoform_ac": "P80897-1", "url": "https://www.uniprot.org/uniprotkb/P80897/entry#P80897-1", "sequence": { "sequence": "NAIFSKKNFETLSEAFSVFQTLKYLAILGGVTFLAG", "length": 36, "header": "sp|P80897-1|RPN2_CHICK Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Gallus gallus OX=9031 GN=RPN2 PE=1 SV=1 CANONICAL=P80897-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Purification and characterization of avian oligosaccharyltransferase. Complete amino acid sequence of the 50-kDa subunit.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Kumar V, Heinemann F S, Ozols J", "evidence": [ { "database": "UniProtKB", "id": "P80897", "url": "https://www.uniprot.org/uniprotkb/P80897" } ], "reference": [ { "type": "PubMed", "id": "8175777", "url": "https://glygen.org/publication/PubMed/8175777" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P80897", "url": "https://www.uniprot.org/uniprotkb/P80897" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P80897-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 36, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P80897-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P80897" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P81021-1", "uniprot_ac": "P81021", "uniprot_id": "VIGLN_CHICK", "mass": { "chemical_mass": 142221.0, "monoisotopic_mass": 142221.0 }, "refseq": {}, "gene_names": [ { "name": "HDLBP", "type": "recommended", "evidence": [ { "id": "P81021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81021" } ] }, { "name": "VGL", "type": "synonym", "evidence": [ { "id": "P81021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81021" } ] } ], "protein_names": [ { "name": "Vigilin", "type": "recommended", "evidence": [ { "id": "P81021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81021/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P81021", "url": "https://www.uniprot.org/uniprotkb/P81021" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HDLBP", "url": "https://www.uniprot.org/uniprotkb/P81021", "locus": { "chromosome": "9", "start_pos": 4604678, "end_pos": 4638006, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023338", "url": "https://www.ensembl.org/id/ENSGALG00010023338" } ] } } ], "crossref": [ { "id": "P81021", "url": "https://alphafold.ebi.ac.uk/entry/P81021", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22406", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22406", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22410", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22410", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22413", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22413", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22418", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22418", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "P81021", "url": "https://www.orthodb.org/?gene=P81021", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10627:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10627:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "P81021", "url": "https://www.uniprot.org/uniprotkb/P81021", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P81021-1", "url": "https://www.uniprot.org/uniprotkb/P81021-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSVAVLTQESFAEHRSGLTQQQVKVTALNSEEENDPPTYKEAFPPLPEKAPCLEAAQEPSGPWSKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLDIMQKTGAHLELSLAKDQGLSIMVSGKLEAVMKARKEIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEILLISAEQDKRAVERLDVEKVYHPFIAGPYNKLVSELMQDTGTRINIPPPSVNKTEIVFTGEKEQLAQAVARVKKIYEEKKKKTTTIAVEVKKSQHKYVIGRKGNSLQEILEKTGVSVEIPPTDSSSETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGLFGQNLAKITQQMPKIHIEFTEGEDKITSEGPTEDVNVAQEQIEVMVKDLINRTDYAEINVDHKFHRHLIGKNGANINRIKDLYKVSVRIPPDNEKSNLIRIEGDPQGVQQAKKELLELASRMENERTKDLIIEQKFHRTIIGQKGERIREIREKFPEVIINFPDPAHKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSFSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPGREQATQRQLLSQGREQTVKLLRHRILAIQKELANITEVEVSIPSKLHNSLIGAKGRFIRSIMEECGGVHIHFPTEGSGSATVTIRAQPRTWRKPRSSCCTWAEEKQTKSYTVDLRAKPEYHKFLIGKGGGNIRKVRDNTGARIIFPTSEDKDQELITIMGTEEAVKEAQKELEALIKNLDNVVEDSMVVDPKHHRHFVIRRGQVLREIADEYGGVMVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTIECTIPQKFHRSIMGPKGSRIQQITRDYGVQIKFPDREENPAPVAEPALQENGEEGGEGKDGKDADPSSPRKCDIIIISGRREKCEAAKEALQALVPVTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLTVTVDPKYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYEKNAEAARDAIMKIVGELEQMVSEDVTLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDNEAMQVYMKPSSHEESKVPSKGFVVRDAPCGTVNNEKAPDMSSSEDFPSFGAQVAPKTLPWGPKR", "length": 1270, "header": "sp|P81021-1|VIGLN_CHICK Isoform 1 of Vigilin OS=Gallus gallus OX=9031 GN=HDLBP PE=2 SV=1 CANONICAL=P81021-1" }, "isoforms": [ { "isoform_ac": "P81021-1", "url": "https://www.uniprot.org/uniprotkb/P81021/entry#P81021-1", "sequence": { "sequence": 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"length": 1270, "header": "sp|P81021-1|VIGLN_CHICK Isoform 1 of Vigilin OS=Gallus gallus OX=9031 GN=HDLBP PE=2 SV=1 CANONICAL=P81021-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Complete cDNA sequence of chicken vigilin, a novel protein with amplified and evolutionary conserved domains.", "journal": "Eur. J. Biochem.", "date": "1992", "authors": "Schmidt C, Henkel B, P\u00f6schl E, Zorbas H, Purschke W G, Gloe T R, M\u00fcller P K", "evidence": [ { "database": "UniProtKB", "id": "P81021", "url": "https://www.uniprot.org/uniprotkb/P81021" } ], "reference": [ { "type": "PubMed", "id": "1606952", "url": "https://glygen.org/publication/PubMed/1606952" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P81021", "url": "https://www.uniprot.org/uniprotkb/P81021" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P81021", "url": "https://www.uniprot.org/uniprotkb/P81021" } ], "pmid": "" } ] } ] 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P81628-1", "uniprot_ac": "P81628", "uniprot_id": "ERP29_CHICK", "mass": { "chemical_mass": 25373.0, "monoisotopic_mass": 25373.0 }, "refseq": { "ac": "NP_001263253", "name": "endoplasmic reticulum resident protein 29 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" }, "gene_names": [ { "name": "ERP29", "type": "recommended", "evidence": [ { "id": "P81628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81628" } ] }, { "name": "C12orf8", "type": "synonym", "evidence": [ { "id": "NP_001263253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" } ] }, { "name": "ERP29", "type": "synonym", "evidence": [ { "id": "NP_001263253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" } ] }, { "name": "RCJMB04_24f23", "type": "synonym", "evidence": [ { "id": "P81628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81628" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum resident protein 29", "type": "recommended", "evidence": [ { "id": "P81628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81628/entry#names_and_taxonomy" } ] }, { "name": "ERp29", "type": "synonym", "evidence": [ { "id": "P81628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81628/entry#names_and_taxonomy" } ] }, { "name": "endoplasmic reticulum resident protein 29 precursor", "type": "synonym", "evidence": [ { "id": "NP_001263253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" } ] }, { "name": "endoplasmic reticulum resident protein 29", "type": "synonym", "evidence": [ { "id": "NP_001263253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720735.1, BU369995.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992432, SAMEA103992533 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ720735.1, BU401484.1, AJ397785.1, BU350207.1, BU139356.1 and CK607880.1. On Feb 2, 2013 this sequence version replaced XP_415173.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001263253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253" } ] }, { "annotation": "Does not seem to be a disulfide isomerase. 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"evidence": [ { "database": "UniProtKB", "id": "Q02173", "url": "https://www.uniprot.org/uniprotkb/Q02173" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "Q02173", "url": "https://www.uniprot.org/uniprotkb/Q02173" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1032, "end_pos": 1034, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1154, "end_pos": 1156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1288, "end_pos": 1290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1351, "end_pos": 1353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, 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] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: HAEL01009114.1, AB253764.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Dec 9, 2021 this sequence version replaced NP_001038142.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001038142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038142" } ] }, { "annotation": "Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. 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The reference sequence was derived from JAENSK010000012.1. On Aug 29, 2006 this sequence version replaced XP_416221.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038103" } ] }, { "annotation": "Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.", "evidence": [ { "database": "UniProtKB", "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9#function" } ] }, { "annotation": "The CENP-H-I complex may function, in part, as a marker directing CENP-A deposition to centromeres.[CENPA, CENPI]", "evidence": [ { "database": "RefSeq", "id": "NP_001038103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038103" }, { "database": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CENPM", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9", "locus": { "chromosome": "1", "start_pos": 49506761, "end_pos": 49500272, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010648", "url": "https://www.ensembl.org/id/ENSGALG00010010648" } ] } } ], "crossref": [ { "id": "Q1T7B9", "url": "https://alphafold.ebi.ac.uk/entry/Q1T7B9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011914", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417982", "url": "https://www.ncbi.nlm.nih.gov/gene/417982", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q1T7B9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q1T7B9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR020987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417982", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417982", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTLPLDI", "url": "https://omabrowser.org/oma/group/CTLPLDI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q1T7B9", "url": "https://www.orthodb.org/?gene=Q1T7B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34436:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34436:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q1T7B9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q1T7B9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001038103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038103", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1T7B9-1", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLRPFDKLPELNSATILLVGAEGGPQQQLAEAMLREKKDFNINIHLASSLPLPSERDHLRPRIDLIAFVIDIKSKYSLKNVQASLAYVDVRFFLGKVCFLVTGVGRANNCSVEMNAIWKLGEDYCSPVIFCELELEGIRVATAQRLLRMLQICAGRVPGVSALYFSLLMRNSAGD", "length": 177, "header": "sp|Q1T7B9-1|CENPM_CHICK Isoform 1 of Centromere protein M OS=Gallus gallus OX=9031 GN=CENPM PE=1 SV=1 CANONICAL=Q1T7B9-1" }, "isoforms": [ { "isoform_ac": "Q1T7B9-1", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9/entry#Q1T7B9-1", "sequence": { "sequence": "MAVLRPFDKLPELNSATILLVGAEGGPQQQLAEAMLREKKDFNINIHLASSLPLPSERDHLRPRIDLIAFVIDIKSKYSLKNVQASLAYVDVRFFLGKVCFLVTGVGRANNCSVEMNAIWKLGEDYCSPVIFCELELEGIRVATAQRLLRMLQICAGRVPGVSALYFSLLMRNSAGD", "length": 177, "header": "sp|Q1T7B9-1|CENPM_CHICK Isoform 1 of Centromere protein M OS=Gallus gallus OX=9031 GN=CENPM PE=1 SV=1 CANONICAL=Q1T7B9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.", "journal": "Nat. Cell Biol.", "date": "2006", "authors": "Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T", "evidence": [ { "database": "UniProtKB", "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9" }, { "database": "RefSeq", "id": "NP_001038103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038103" } ], "reference": [ { "type": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "pathway": [ { "id": "gga:417982", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417982", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L681-1", "protein_name": "Centromere protein M", "gene_name": "Cenpm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VGVPVRTWLSRVSRRRPADPSELVSTEDALLQQLAESVLKIDCATELRVHLANSLPLPSNANRPRIDLIVFVINLHSKYSLQKVEESLNHVDSSFFLGKVCFLVTGAGRESHCSVHQNTVMKLAHTYRSPLLFCDLQVESFRAAMAQRLVRVLQVCAGHVPGISALNLLSLLRSPENPPSKEL", "length": 183 }, "evidence": [ { "id": "Q1T7B9", "url": "https://omabrowser.org/oma/group/Q1T7B9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IBR2-1", "protein_name": "Centromere protein M", "gene_name": "Cenpm", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVLRSMDKLPDLNRATILLVGTEDALLQKLAESMLQEHCASELRVHLANSLPLPSTVNRPRIDLIVFVINLHSKYSLRKVEECLSHVDSSFFLGKVCFLATGAGRESHCSIHQNTVIKLARTYRSPLLFCDLEVGSFRATMAQRLVRMLQICAGHVPGISAVNLLSLLRCSDSTPSKEL", "length": 180 }, "evidence": [ { "id": "Q1T7B9", "url": "https://omabrowser.org/oma/group/Q1T7B9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TBH1-1", "protein_name": "Centromere protein M", "gene_name": "CENPM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSALRPLDKLPGLNTATILLVGTEDALLQQLADSMLKADCTSELKVHLARSLPLPCSVNRPRIDLIVFVVNLHSKLSLQSVEESLCHLDAAFFLGKVAFLATGAGRDSHCSIHRNTVVKLAHTYRSPLLFCDLEIEDFRAAMAQRLVRLLQICAGHVPGVSALNLLSLMRGSENPSLEDL", "length": 180 }, "evidence": [ { "id": "Q1T7B9", "url": "https://omabrowser.org/oma/group/Q1T7B9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQA0-1", "protein_name": "Centromere protein M", "gene_name": "Cenpm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVLRSMDKLPDLNRATVLLVSTEDALLQQLAESMLKDDCASELRVHLANSLPLPSNVNRPRIDLIVFVINLHSKYSLQKVEEFLQHVDSSFFLGKVCFLVTGAGQESHCSVHQNTVIKLAHTYRSPLLLCDLQVESFRAAMARRLVRILQICAGHVPGVSALNLMSLLRSPENPPSKEL", "length": 180 }, "evidence": [ { "id": "Q1T7B9", "url": "https://omabrowser.org/oma/group/Q1T7B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSP4-1", "protein_name": "Centromere protein M", "gene_name": "CENPM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVLRPLDKLPGLNTATILLVGTEDALLQQLADSMLKEDCASELKVHLAKSLPLPSSVNRPRIDLIVFVVNLHSKYSLQNTEESLRHVDASFFLGKVCFLATGAGRESHCSIHRHTVVKLAHTYQSPLLYCDLEVEGFRATMAQRLVRVLQICAGHVPGVSALNLLSLLRSSEGPSLEDL", "length": 180 }, "evidence": [ { "id": "Q1T7B9", "url": "https://omabrowser.org/oma/group/Q1T7B9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q1T7B9", "url": "https://www.uniprot.org/uniprotkb/Q1T7B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q1T7B9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 177, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q1T7B9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q1T7B9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q1T7C0-1", "uniprot_ac": "Q1T7C0", "uniprot_id": "CENPL_CHICK", "mass": { "chemical_mass": 37893.0, "monoisotopic_mass": 37893.0 }, "refseq": { "ac": "NP_001006569", "name": "centromere protein L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" }, "gene_names": [ { "name": "CENPL", "type": "recommended", "evidence": [ { "id": "Q1T7C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ] }, { "name": "CENPL", "type": "synonym", "evidence": [ { "id": "NP_001006569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" } ] }, { "name": "RCJMB04_9b13", "type": "synonym", "evidence": [ { "id": "Q1T7C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ] } ], "protein_names": [ { "name": "Centromere protein L", "type": "recommended", "evidence": [ { "id": "Q1T7C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0/entry#names_and_taxonomy" } ] }, { "name": "CENP-L", "type": "synonym", "evidence": [ { "id": "NP_001006569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" }, { "id": "Q1T7C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0/entry#names_and_taxonomy" } ] }, { "name": "centromere protein L", "type": "synonym", "evidence": [ { "id": "NP_001006569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01007473.1, HAEL01001254.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000237.1. On Sep 23, 2021 this sequence version replaced NP_001006569.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001006569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" } ] }, { "annotation": "Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0#function" } ] }, { "annotation": "The CENP-H-I complex may function, in part, as a marker directing CENP-A deposition to centromeres.[CENPA, CENPI]", "evidence": [ { "database": "RefSeq", "id": "NP_001006569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" }, { "database": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CENPL", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0", "locus": { "chromosome": "8", "start_pos": 5549387, "end_pos": 5554652, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010756", "url": "https://www.ensembl.org/id/ENSGALG00010010756" } ] } } ], "crossref": [ { "id": "Q1T7C0", "url": "https://alphafold.ebi.ac.uk/entry/Q1T7C0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038411", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038411", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426563", "url": "https://www.ncbi.nlm.nih.gov/gene/426563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q1T7C0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q1T7C0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR025204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426563", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426563", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TACKMDQ", "url": "https://omabrowser.org/oma/group/TACKMDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q1T7C0", "url": "https://www.orthodb.org/?gene=Q1T7C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31740:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31740:SF2", "database": "PANTHER", "categories": [ "Protein 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"https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1T7C0-1", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGRPAGSAIEMEGAMRTLPSSGRPSGTGWQSRGPLFGRNYGLSPGSRLLPPRCQENADPQKMAFLLRKQWTLYSVSPLYKFSSADLKDYARMLGVFIAAEKQKGLAVDVDGELGIKVAMSGLPELRGSEQDPAAVLVQLSLRSSVSPKNSEEKLIWSGWFCCVAGDDLLENLPENFTCLPLFLVNGAESYTAIVGSWFQKTFDCCFRRLAISPLNLTWMAAMWTGCKVDKNTAATELLFSVPHLPQPLDISYAIHPEDAKALWDTVQKTPGEITQEEVDVFMECLYSHFHRHFKIHLSATKLVKVSTGIASAHCDGIIKFLQSQYLIGVLMLLTELAISQIQ", "length": 344, "header": "sp|Q1T7C0-1|CENPL_CHICK Isoform 1 of Centromere protein L OS=Gallus gallus OX=9031 GN=CENPL PE=1 SV=1 CANONICAL=Q1T7C0-1" }, "isoforms": [ { "isoform_ac": "Q1T7C0-1", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0/entry#Q1T7C0-1", "sequence": { "sequence": "MAGGRPAGSAIEMEGAMRTLPSSGRPSGTGWQSRGPLFGRNYGLSPGSRLLPPRCQENADPQKMAFLLRKQWTLYSVSPLYKFSSADLKDYARMLGVFIAAEKQKGLAVDVDGELGIKVAMSGLPELRGSEQDPAAVLVQLSLRSSVSPKNSEEKLIWSGWFCCVAGDDLLENLPENFTCLPLFLVNGAESYTAIVGSWFQKTFDCCFRRLAISPLNLTWMAAMWTGCKVDKNTAATELLFSVPHLPQPLDISYAIHPEDAKALWDTVQKTPGEITQEEVDVFMECLYSHFHRHFKIHLSATKLVKVSTGIASAHCDGIIKFLQSQYLIGVLMLLTELAISQIQ", "length": 344, "header": "sp|Q1T7C0-1|CENPL_CHICK Isoform 1 of Centromere protein L OS=Gallus gallus OX=9031 GN=CENPL PE=1 SV=1 CANONICAL=Q1T7C0-1" }, "locus": { "chromosome": "8", "start_pos": 5554631, "end_pos": 5552710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025682.1", "url": "https://www.ensembl.org/id/ENSGALT00010025682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014474.1", "url": "https://www.ensembl.org/id/ENSGALP00010014474.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.", "journal": "Nat. Cell Biol.", "date": "2006", "authors": "Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" }, { "database": "RefSeq", "id": "NP_001006569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006569" } ], "reference": [ { "type": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "pathway": [ { "id": "gga:426563", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426563", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GZL1-1", "protein_name": "Centromere protein L", "gene_name": "Cenpl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPYDSQGSTSRRRTSNLKDYFVGATPLQKRLESIRRQSSFFPSPPRRKIPQGTELQEEIDPQKVGFLLHKQWTVYSLTPLYKFSYTNFKEYSRLLSAFIAAEKQKGLAVQVGEDFNIKVIFSNLVGVRGTQRDPEAFLVQILSKSQSSREHREGRVLWTGWFCCVFGESLLETVSEDFTCLPLFLANGAESNTSLIGGWFQKTFDCCFSPLAISAFHLSWMAAMWTACEMDHYMATTEFFWSVPCSPQSLDISYAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFRIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYMTELAIFKTE", "length": 345 }, "evidence": [ { "id": "Q1T7C0", "url": "https://omabrowser.org/oma/group/Q1T7C0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZAU7-1", "protein_name": "Centromere protein L", "gene_name": "Cenpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTYDSQGPTSRRRTSNLKDYFVSATPLQKRLKLARRQSSVFPSPSRRKIPQCSQLQEDIDPQKVAFLLHKQWTVYSLTPLYKFSYSNLKDYSRLLSAFIAAEKQKGLAVEVGEDFNIKVIFSTLLGVKGTQRDPEAFLVQIRSESQSSREHRQDKVLWTGWFCCVFGENLQETVSEDFTCLPLFLAHGAESNTSLIGGWFQKTFDCCFSPLAISAFNLSWMAAMWTACKMDHYMATTEFFWSVPCSPQSLDISYAIHPEDAKALWDSVHKTPGEVTQEEVDLFMNCLYSHFHRHFRIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYMTELAIFQIE", "length": 345 }, "evidence": [ { "id": "Q1T7C0", "url": "https://omabrowser.org/oma/group/Q1T7C0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EA18-1", "protein_name": "Centromere protein L", "gene_name": "CENPL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSYDAPELTPRQDASSRLKDFFVGATPLQKRLESVRKQTSFIPTPPRRKIPQGSQLQEDVDPQKFAFLLHKQWTLYSLTPLYKFSYTNFKEYSKLLNAFIAAEKQKGLAVEVGDDFNIKVVFSTLMGVKGTQRDPEAFLVQILSKSQLPSEHKEGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLVNGAETNTAIIGTWFQKTFDCYFRPLAINAFNLSWMAAMWTACKMDHYMATTEFLWSVPCSPHSLDISYAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASAHTDGKIKILCPKYLIGVLAYLTELAVFQIE", "length": 346 }, "evidence": [ { "id": "Q1T7C0", "url": "https://omabrowser.org/oma/group/Q1T7C0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DRD4-1", "protein_name": "Centromere protein L", "gene_name": "cenpl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFNLLPAFSLGVLLIVMEGRGSAVNTPASRPVTRKSKSYGRSCVEAPSYFWQTPGHLTVLKVPTSRGAAKSQIITNKVDPEHIALLVKNEWKLSYVTPLHHFRHTQLKSYAKHLSAFIVAEKQQGVAVEVGLDAGFKVTFTAVLGLAETDEDAETVFIQIQSKPVFAAAADAPKVVWRGWLTCVNGDPEYLRSLPPDFVSLPLFCTSGPESLTNLVKSWFERAFDCNFGSLALNSSTLNWLAALWTGCHPACNIRYLKLSWSLPTEPPLDVLYTVNPQDAWELWNSIHPQENTDDRIDIKDVQAFMSGMETHFFRHFKIHLSAGTLLKVSTALGSAHHDGKIKIGNSDYITTLLALLTECALLKMPT", "length": 367 }, "evidence": [ { "id": "Q1T7C0", "url": "https://omabrowser.org/oma/group/Q1T7C0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N0S6-1", "protein_name": "Centromere protein L", "gene_name": "CENPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVIFSTLLGMKGTQRDPEAFLVQIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFLWSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYLTELAIFQIE", "length": 344 }, "evidence": [ { "id": "Q1T7C0", "url": "https://omabrowser.org/oma/group/Q1T7C0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C0", "url": "https://www.uniprot.org/uniprotkb/Q1T7C0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q1T7C0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q1T7C0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q1T7C0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q1T7C1-1", "uniprot_ac": "Q1T7C1", "uniprot_id": "CENPK_CHICK", "mass": { "chemical_mass": 30720.0, "monoisotopic_mass": 30720.0 }, "refseq": { "ac": "NP_001038128", "name": "centromere protein K isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" }, "gene_names": [ { "name": "CENPK", "type": "recommended", "evidence": [ { "id": "Q1T7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C1" } ] }, { "name": "CENP-K", "type": "synonym", "evidence": [ { "id": "NP_001038128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] }, { "name": "CENPK", "type": "synonym", "evidence": [ { "id": "NP_001038128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] }, { "name": "FKSG14", "type": "synonym", "evidence": [ { "id": "NP_001038128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] } ], "protein_names": [ { "name": "Centromere protein K", "type": "recommended", "evidence": [ { "id": "Q1T7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C1/entry#names_and_taxonomy" } ] }, { "name": "CENP-K", "type": "synonym", "evidence": [ { "id": "Q1T7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1T7C1/entry#names_and_taxonomy" } ] }, { "name": "centromere protein K isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001038128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] }, { "name": "leucine zipper protein FKSG14", "type": "synonym", "evidence": [ { "id": "NP_001038128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX936045.1, BX930956.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. On Aug 29, 2006 this sequence version replaced XP_424750.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" } ] }, { "annotation": "Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.", "evidence": [ { "database": "UniProtKB", "id": "Q1T7C1", "url": "https://www.uniprot.org/uniprotkb/Q1T7C1#function" } ] }, { "annotation": "The CENP-H-I complex may function, in part, as a marker directing CENP-A deposition to centromeres.[CENPA, CENPI]", "evidence": [ { "database": "RefSeq", "id": "NP_001038128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038128" }, { "database": "PubMed", "id": "16622420", "url": "https://glygen.org/publication/PubMed/16622420" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, 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"https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420367", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q2PC93", "url": "https://www.orthodb.org/?gene=Q2PC93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q2PC93", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q2PC93", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q2PC93", "url": "https://www.uniprot.org/uniprotkb/Q2PC93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2PC93-1", "url": "https://www.uniprot.org/uniprotkb/Q2PC93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIVATVLLWVVTEAARGRWCERTEQVTEEEVVMPRREDVVPCPSMYQYSLAGWRIDLNRMRQVYGGERGVPPTSTHPGAAMCYIYRPPETQLVVRNRTVRACCAGWSGPHCTEVEGSLGQCHASWQCQDALGAHNLSTVSMAECCRQPWGHSWRNGSSALCFACSRQPLTGDVPLPTAPRGPAARHRGPTASCTVWAGSRYRSFDGRHFGFQGECAYSLAASTDSTWAVSITPGSPPVLHMTFGLDTVVAQGHNISVNGVAVPEGRQHLHGGISVTWLGDFVAVESGLGVHLKLDGRGTVYVTVSAELRGSTKGLCGPYNDDPIDDFLRVEGDVAPLAASFGNSWRIPDANPELSCSDAVEPSPGCAMGSTAQRAAEAMCGMLLTDPFRQCHEAVDPHGFYEACLELHCREGGTGPSPPPAVCDTLATYVRDCAQRRAYIEWRRPGLCEQQCGHGQRYSDCVSSCPASCMAAGTAEEGHCRDDCASGCECTPGLLLDRGACIPQSACPCLHRGHIYAPGQSIRQRCNQCTCRGGRWLCTQDRCAAECAVLGDLHYITFDRRRFSFPGACEYTLVQDFVEGTLRITAEQEACGGHQPLSCLRALSITVPGASARLHSTGEVVVDGRVVPLPFASAALTVRRASSSFLLLQTFGAHLLWGLETPAAYITLQPAFANKVRGLCGTYNWDQRDDFATPAGDVEVGVTAFANKYRVSTDCPVLSPVPFEPCSTYAPRRELAAAACAILHGASFQPCHHLVDREPFHQLCLYDVCACPAGKHCLCPALAAYARECAQEGAALSWRNESFCGTQCRGGQVYQECSSPCGRTCADLRLDGASSCPSLDNICVSGCNCPEGPVLDDGGQCVPPGVCPCQHSSQLYPAGSKIRQGCNACMCTAGTWSCTDAPCPDAAFCPGDLVYVFGSCLRTCDSAEPNGTCTGIADGCVCPPGTVFLDERCVPPEECPCQHNGRLYHPNDTIVRDCNTCVCRQQRWQCSSEDCMGTCVATGDPHYITFDGRAFSFLGDCEYVLVREANGLFTVTAENVPCGTSGVTCTKSVVVEMGNTVVHMLRGRDVTVNGVSVRPPKVYSGNGLTLQRAGIFLLLLSRLGLAVLWDGGTRVYIRLQPQHRGRVVGLCGNFDRDAENDLASQQGVLEPTAELFGNSWRVSLLCPEVDGTTAQHPCTDNPHRATWARKRCSILTQRLFAPCHDEVPCQHFYDWCIFDACGCDSGGDCECLCTAIATYAEECSQRGIHIRWRSQDLCPMQCDGGQEYSACGPPCPQTCRNLGLELPEHCDTMSCLEGCFCPEGKVLHEGSCIDPAECPCFWQGIAFPDSAVVQQGCRNCSCTAGLWQCVPTAEPCPAQPHCPDSEFPCRSGGRCVPGAWLCDNEDDCGDGSDEVCALHCAPHQHRCADGQCVPWGARCDGLSDCGDGSDERGCPPPPCAPPEFRCASGRCIPRAHVCNGELDCGFADDSDEAGCSPSCSVGEFQCAAGRCVPYPHRCNGHDDCGDFSDERGCVCPAGHFQCPDAQCLPPAALCDGMQDCGDGTDEAFCPDRITCAPGQLPCPDGSCVSQVKLCDGIWDCRDGWDESSVRCMVSWAPPAPTQLPTVPANGTAAPVCGPYEFPCRSGQCVPRGWVCDSEADCPDNSDELGCNRSCVLGHFPCALGAHCIHYDHLCDGIPHCPDHSDESDDNCGSTQIPPCPGHFVCNNRVCVNATRVCDGALDCPQGEDELACEGYVPTGERNQTVGPCAEYSCRDGDCITFKQVCNGLPDCRDGDMASGWLPSDEWDCGQWGPWAPWGICSHSCGLGQQLRARECSQRTPGVLHQCHGEATQARPCFSTACPVDGAWSEWTMWSNCTQGCEGVVVRQRHCQPPRDGGRPCAALPATAHATLEIGTCQQDGCPPASCPGGLQPRPCAPCPASCADLASRAPCRREQCTPGCWCAEGLVLDGERGCVRPRECRCEVDGLRYWPGQRMKLNCRLCTCLDGQPRRCRHNPACSVSCSWSAWSPWGECLGPCGVQSIQWSFRSPSHPGKHGTNRQCRGIYRKARRCQTEPCQECEHQGRSRAQGDRWRWGPCHVCQCLPGPEVRCSPYCARSAVGCPQGQVLVEGKGDSCCFCAQIGDNVTAIPTALTMEPPSTMPGEPSDSPLPTFPLPSPGDPCYSPLGIASLPDSSFTASAEQQQHPARAARLHHVSPGLELQGWAPPADTVPGLPSHLPFLQLDLLQTTNLTGVVVQGAGAGDAFITAFQLQFSTDGNRWHNYQQLFQGNWDATTPVVQPLDHMVQARYIRILPQGFHNAIFLRAELLGCPTVPLDLAVTTAVTPAPCGTGEFWCGVSCVTASRRCDGATDCPGGADEAGCEPPSSTTLPTHPASLTTPGSAGILGLTAEPPVAPPAAVPEGTSAWLTVGSTSPAVPSTTGLPGVPTATITPRGPPSAGPPSPGMAAVTVSHPVMGPPALPMPPTGVPTPTSAEPPLPRLLCPPDQFLCDALGCVDAAMVCDGQQDCLDGSDEAHCGALPTSGSSPSPLAWPSSPPPTCSPKQFSCGTGECLALEKRCDLSRDCADGSDESSCADCILSPWGGWSQCSHSCGLGVTSRQRVLLRGALPGGTCHTPRLDTRACFLRACPVPGAWAAWGVWSSCDAECGGGMRSRTRSCTDPPPKNGGQPCAGEALQSQPCNLQPCGDTRECGPGMVLVQEGDCVQGLVPPCPQVCGDLSATSSCQSPCQEGCRCPPGLFLQEGTCVNASQCHCHQGQQRWLPSQVFLRDGCSQCVCRDGVVTCEDTACPIACAWSAWSLWTLCDRSCGVGMQERFRSPSNPAAANGGAPCDGDTREVRECHTPCATAEPSSGWSSWTPWSPCSRSCFHHVDQRGRRHRFRHCEGMGTCPGLGVQEEPCDTAPCPVAGVWMPWSAWSECSAPCDAGVQTRSRTCTPPAFGGAECTGPHLQTRNCNTRPCGAQCPDTMQYLTAEECRHSEGRCPWICQDLGAGVACTAQCQPGCHCPAGLLLQNGTCVPPSHCLCHHRGHLYQPGDINALDTCNNCTCVTGQMVCSTETCPVPCTWSNWTAWSTCSHSCDVGMRRRYRVPIVPPLAGGGPPCQGPSMEVEFCSLQPCRAVAPWGPWSECSVSCGGGYRNRTRDGPPLHSLEFSTCNPAPCPGKEPGVCPPGKQWQACAQGAASCAELSAAPPADGSCHPGCYCPPGALLLNNECVAEAACPCAVDGVLYQPGDVVPQGCHNCSCIAGRVTNCSQEDCGDVDGPWTPWTPWSECSASCGPGRQRRYRFCSAHPGVPCAEPQPQERPCARQPCHSPDCAAVPGSVFSHCRPPCPRSCDDISHCVWHRQPGCYCTNGTLLDATGTACVALENCTCLDAHSGQRHQPGQSVPRGDGCNNCTCTQGRLLCTGLPCPVPGAWCEWSPWTPCSRSCGDEAATRHRVCSCPAPQQGGAGCPGGLEGHGDTGMQLQHQECPSVPPCPEDGAWAAWGPWSGCGGCGGQAVRTRSCSSPPARFGGLPCAGEARQSRACPWATSSCPECAGGLVAFTCGKPCPHSCEDLREDTACMATPRCLPACACPHGQLLQDGDCVPPELCRCAWAPSKNGSIWEQDGAVPMQELQPGETVQRHCQNCTCKSGTLQCHAEPGCRADGGWSPWGPWSPCSPGCQAGTQLASRQCNNPTPQLGGRGCSGHSQRQRPCPATEGCPEEEPWGEWSPWGPCSASCGGGEQLRHRDCPPPGGCPGLALQSKTCNTHVCREAGCPPGRLYRECQQGEGCPYSCAHLAGRIACFPGGCQEGCHCPTGTLLHHGHCLQECPCVLTAEVLRKLRNSSADLQAAPHLLGTRGPPLALDQELPPGSTIHSACTSCTCLHGRLNCSEPVCPRDGGFSPWGPWSSCSRSCGGLGVMTRRRGCTNPEPARGGRDCAGPRSDSKYCQSPECPAVPTTEPGPGVAGAEEEEGFGPWSPWSPCSKTCTHPERPATKTRERPCVGTAVCSGDGFQEQPCNLPLCSDVPPCQGEDCAGLNCSWAPWGPWTECSRSCGVGRQQRLRAYSPPGASGRWCPGILSAFVQRRFCSLQACKVDGAWSAWSPWSRCDRTCGGGRAVRTRSCTRPPPKNGGQRCPGERHQLHLCNAQPCDDSCPPGMALVTCANHCPRHCGDLQEGIVCREEEHCEPGCRCPNGTLEQDGGCVPLAHCECTDAQGHGWVPGSTHHDGCNNCTCLEGRLRCTDRLCPPLRCPWSRWSRWSPCSVTCGDGQQTRFRTPTAGSWDEECQGEQMENRGCAAGPCPPLCPQGSWERRLGDMWLQGECQRCTCTPEGTVCEDTTCAGAEHCTWGTWSPCSRSCGTGLASREGSCPCPFPGPPGAVCNASTGDGARPHREVQACYLRPCPAECSWSAWSSWGGCSCSSPLQHRYRHRHGTGLCVGLDVELHPCNTSGCSESSCEPPFEFQPCSPPCARLCSTLQHPELCPAQSHCLPGCFCPQGLLEQRSACVPPEQCDCLHTNESGDLVTLSPGDIILLGCKECVCQDGALQCSSEGCQGLLPLSPWSEWTPCSTCLPLFPSHLGDATPHVSVQHRYRACLDPQSGQPWSGDTAVCSAELQQQRLCPDPDICQELCLWSPWGPWGPCQQPCSGSFRLRHRHLQRLAGSGQCQGAQTQSESCNTAVCPGEDCEKQGRVFATTCANSCPRACADLWQHVECVQGGCKPGCRCPQGQLLQDGLCVPTAQCRCGLSGDNGTQELWPGQEATIECHNCTCENGTMVCPALPCPSYGPWSTWSPCSSSCGSGRTSRHRTCEPNPGGVPCMASGMQETAECSPQPCPAGCQLSPWSPWSPCSSSCGGGRSERSRELLGGEEEPCPIPALRQHRVCNVHNCTQECPRSQVHRECANACPHACADLRPQTQCLPQPCQPGCACPPGQVLQDGACVPPEECRCTLDSTMPGVLNLSREEQEQEHAPGSRLQHRCNTCICIRGTFNCSQEECNVDCLWSPWSPWSPCSVTCGMGERLSHRHPLRQRLYEGAECLGPPVRRAACHLPDCACPEGERWQGHEVPPGCEQSCRDILDETPANCTPSPSPGCTCEPGHYRNSSGHCVPSTLCECLHQGQLHQPGSEWQEQCARCRCVDGKANCTDGCTPLSCPEGEVKVREPGRCCPVCRMEWPEEPSSMCRRFTELRNITKGPCSLPNVEVSFCSGRCPSRTAVTPEEPYLQTLCECCSYRLDPGSPVRILSLPCAGGAAEPVVLPIIHSCECSSCQGGDFSKR", "length": 5255, "header": "sp|Q2PC93-1|SSPO_CHICK Isoform 1 of SCO-spondin OS=Gallus gallus OX=9031 GN=SSPO PE=2 SV=1 CANONICAL=Q2PC93-1" }, "isoforms": [ { "isoform_ac": "Q2PC93-1", "url": "https://www.uniprot.org/uniprotkb/Q2PC93/entry#Q2PC93-1", "sequence": { "sequence": "MGIVATVLLWVVTEAARGRWCERTEQVTEEEVVMPRREDVVPCPSMYQYSLAGWRIDLNRMRQVYGGERGVPPTSTHPGAAMCYIYRPPETQLVVRNRTVRACCAGWSGPHCTEVEGSLGQCHASWQCQDALGAHNLSTVSMAECCRQPWGHSWRNGSSALCFACSRQPLTGDVPLPTAPRGPAARHRGPTASCTVWAGSRYRSFDGRHFGFQGECAYSLAASTDSTWAVSITPGSPPVLHMTFGLDTVVAQGHNISVNGVAVPEGRQHLHGGISVTWLGDFVAVESGLGVHLKLDGRGTVYVTVSAELRGSTKGLCGPYNDDPIDDFLRVEGDVAPLAASFGNSWRIPDANPELSCSDAVEPSPGCAMGSTAQRAAEAMCGMLLTDPFRQCHEAVDPHGFYEACLELHCREGGTGPSPPPAVCDTLATYVRDCAQRRAYIEWRRPGLCEQQCGHGQRYSDCVSSCPASCMAAGTAEEGHCRDDCASGCECTPGLLLDRGACIPQSACPCLHRGHIYAPGQSIRQRCNQCTCRGGRWLCTQDRCAAECAVLGDLHYITFDRRRFSFPGACEYTLVQDFVEGTLRITAEQEACGGHQPLSCLRALSITVPGASARLHSTGEVVVDGRVVPLPFASAALTVRRASSSFLLLQTFGAHLLWGLETPAAYITLQPAFANKVRGLCGTYNWDQRDDFATPAGDVEVGVTAFANKYRVSTDCPVLSPVPFEPCSTYAPRRELAAAACAILHGASFQPCHHLVDREPFHQLCLYDVCACPAGKHCLCPALAAYARECAQEGAALSWRNESFCGTQCRGGQVYQECSSPCGRTCADLRLDGASSCPSLDNICVSGCNCPEGPVLDDGGQCVPPGVCPCQHSSQLYPAGSKIRQGCNACMCTAGTWSCTDAPCPDAAFCPGDLVYVFGSCLRTCDSAEPNGTCTGIADGCVCPPGTVFLDERCVPPEECPCQHNGRLYHPNDTIVRDCNTCVCRQQRWQCSSEDCMGTCVATGDPHYITFDGRAFSFLGDCEYVLVREANGLFTVTAENVPCGTSGVTCTKSVVVEMGNTVVHMLRGRDVTVNGVSVRPPKVYSGNGLTLQRAGIFLLLLSRLGLAVLWDGGTRVYIRLQPQHRGRVVGLCGNFDRDAENDLASQQGVLEPTAELFGNSWRVSLLCPEVDGTTAQHPCTDNPHRATWARKRCSILTQRLFAPCHDEVPCQHFYDWCIFDACGCDSGGDCECLCTAIATYAEECSQRGIHIRWRSQDLCPMQCDGGQEYSACGPPCPQTCRNLGLELPEHCDTMSCLEGCFCPEGKVLHEGSCIDPAECPCFWQGIAFPDSAVVQQGCRNCSCTAGLWQCVPTAEPCPAQPHCPDSEFPCRSGGRCVPGAWLCDNEDDCGDGSDEVCALHCAPHQHRCADGQCVPWGARCDGLSDCGDGSDERGCPPPPCAPPEFRCASGRCIPRAHVCNGELDCGFADDSDEAGCSPSCSVGEFQCAAGRCVPYPHRCNGHDDCGDFSDERGCVCPAGHFQCPDAQCLPPAALCDGMQDCGDGTDEAFCPDRITCAPGQLPCPDGSCVSQVKLCDGIWDCRDGWDESSVRCMVSWAPPAPTQLPTVPANGTAAPVCGPYEFPCRSGQCVPRGWVCDSEADCPDNSDELGCNRSCVLGHFPCALGAHCIHYDHLCDGIPHCPDHSDESDDNCGSTQIPPCPGHFVCNNRVCVNATRVCDGALDCPQGEDELACEGYVPTGERNQTVGPCAEYSCRDGDCITFKQVCNGLPDCRDGDMASGWLPSDEWDCGQWGPWAPWGICSHSCGLGQQLRARECSQRTPGVLHQCHGEATQARPCFSTACPVDGAWSEWTMWSNCTQGCEGVVVRQRHCQPPRDGGRPCAALPATAHATLEIGTCQQDGCPPASCPGGLQPRPCAPCPASCADLASRAPCRREQCTPGCWCAEGLVLDGERGCVRPRECRCEVDGLRYWPGQRMKLNCRLCTCLDGQPRRCRHNPACSVSCSWSAWSPWGECLGPCGVQSIQWSFRSPSHPGKHGTNRQCRGIYRKARRCQTEPCQECEHQGRSRAQGDRWRWGPCHVCQCLPGPEVRCSPYCARSAVGCPQGQVLVEGKGDSCCFCAQIGDNVTAIPTALTMEPPSTMPGEPSDSPLPTFPLPSPGDPCYSPLGIASLPDSSFTASAEQQQHPARAARLHHVSPGLELQGWAPPADTVPGLPSHLPFLQLDLLQTTNLTGVVVQGAGAGDAFITAFQLQFSTDGNRWHNYQQLFQGNWDATTPVVQPLDHMVQARYIRILPQGFHNAIFLRAELLGCPTVPLDLAVTTAVTPAPCGTGEFWCGVSCVTASRRCDGATDCPGGADEAGCEPPSSTTLPTHPASLTTPGSAGILGLTAEPPVAPPAAVPEGTSAWLTVGSTSPAVPSTTGLPGVPTATITPRGPPSAGPPSPGMAAVTVSHPVMGPPALPMPPTGVPTPTSAEPPLPRLLCPPDQFLCDALGCVDAAMVCDGQQDCLDGSDEAHCGALPTSGSSPSPLAWPSSPPPTCSPKQFSCGTGECLALEKRCDLSRDCADGSDESSCADCILSPWGGWSQCSHSCGLGVTSRQRVLLRGALPGGTCHTPRLDTRACFLRACPVPGAWAAWGVWSSCDAECGGGMRSRTRSCTDPPPKNGGQPCAGEALQSQPCNLQPCGDTRECGPGMVLVQEGDCVQGLVPPCPQVCGDLSATSSCQSPCQEGCRCPPGLFLQEGTCVNASQCHCHQGQQRWLPSQVFLRDGCSQCVCRDGVVTCEDTACPIACAWSAWSLWTLCDRSCGVGMQERFRSPSNPAAANGGAPCDGDTREVRECHTPCATAEPSSGWSSWTPWSPCSRSCFHHVDQRGRRHRFRHCEGMGTCPGLGVQEEPCDTAPCPVAGVWMPWSAWSECSAPCDAGVQTRSRTCTPPAFGGAECTGPHLQTRNCNTRPCGAQCPDTMQYLTAEECRHSEGRCPWICQDLGAGVACTAQCQPGCHCPAGLLLQNGTCVPPSHCLCHHRGHLYQPGDINALDTCNNCTCVTGQMVCSTETCPVPCTWSNWTAWSTCSHSCDVGMRRRYRVPIVPPLAGGGPPCQGPSMEVEFCSLQPCRAVAPWGPWSECSVSCGGGYRNRTRDGPPLHSLEFSTCNPAPCPGKEPGVCPPGKQWQACAQGAASCAELSAAPPADGSCHPGCYCPPGALLLNNECVAEAACPCAVDGVLYQPGDVVPQGCHNCSCIAGRVTNCSQEDCGDVDGPWTPWTPWSECSASCGPGRQRRYRFCSAHPGVPCAEPQPQERPCARQPCHSPDCAAVPGSVFSHCRPPCPRSCDDISHCVWHRQPGCYCTNGTLLDATGTACVALENCTCLDAHSGQRHQPGQSVPRGDGCNNCTCTQGRLLCTGLPCPVPGAWCEWSPWTPCSRSCGDEAATRHRVCSCPAPQQGGAGCPGGLEGHGDTGMQLQHQECPSVPPCPEDGAWAAWGPWSGCGGCGGQAVRTRSCSSPPARFGGLPCAGEARQSRACPWATSSCPECAGGLVAFTCGKPCPHSCEDLREDTACMATPRCLPACACPHGQLLQDGDCVPPELCRCAWAPSKNGSIWEQDGAVPMQELQPGETVQRHCQNCTCKSGTLQCHAEPGCRADGGWSPWGPWSPCSPGCQAGTQLASRQCNNPTPQLGGRGCSGHSQRQRPCPATEGCPEEEPWGEWSPWGPCSASCGGGEQLRHRDCPPPGGCPGLALQSKTCNTHVCREAGCPPGRLYRECQQGEGCPYSCAHLAGRIACFPGGCQEGCHCPTGTLLHHGHCLQECPCVLTAEVLRKLRNSSADLQAAPHLLGTRGPPLALDQELPPGSTIHSACTSCTCLHGRLNCSEPVCPRDGGFSPWGPWSSCSRSCGGLGVMTRRRGCTNPEPARGGRDCAGPRSDSKYCQSPECPAVPTTEPGPGVAGAEEEEGFGPWSPWSPCSKTCTHPERPATKTRERPCVGTAVCSGDGFQEQPCNLPLCSDVPPCQGEDCAGLNCSWAPWGPWTECSRSCGVGRQQRLRAYSPPGASGRWCPGILSAFVQRRFCSLQACKVDGAWSAWSPWSRCDRTCGGGRAVRTRSCTRPPPKNGGQRCPGERHQLHLCNAQPCDDSCPPGMALVTCANHCPRHCGDLQEGIVCREEEHCEPGCRCPNGTLEQDGGCVPLAHCECTDAQGHGWVPGSTHHDGCNNCTCLEGRLRCTDRLCPPLRCPWSRWSRWSPCSVTCGDGQQTRFRTPTAGSWDEECQGEQMENRGCAAGPCPPLCPQGSWERRLGDMWLQGECQRCTCTPEGTVCEDTTCAGAEHCTWGTWSPCSRSCGTGLASREGSCPCPFPGPPGAVCNASTGDGARPHREVQACYLRPCPAECSWSAWSSWGGCSCSSPLQHRYRHRHGTGLCVGLDVELHPCNTSGCSESSCEPPFEFQPCSPPCARLCSTLQHPELCPAQSHCLPGCFCPQGLLEQRSACVPPEQCDCLHTNESGDLVTLSPGDIILLGCKECVCQDGALQCSSEGCQGLLPLSPWSEWTPCSTCLPLFPSHLGDATPHVSVQHRYRACLDPQSGQPWSGDTAVCSAELQQQRLCPDPDICQELCLWSPWGPWGPCQQPCSGSFRLRHRHLQRLAGSGQCQGAQTQSESCNTAVCPGEDCEKQGRVFATTCANSCPRACADLWQHVECVQGGCKPGCRCPQGQLLQDGLCVPTAQCRCGLSGDNGTQELWPGQEATIECHNCTCENGTMVCPALPCPSYGPWSTWSPCSSSCGSGRTSRHRTCEPNPGGVPCMASGMQETAECSPQPCPAGCQLSPWSPWSPCSSSCGGGRSERSRELLGGEEEPCPIPALRQHRVCNVHNCTQECPRSQVHRECANACPHACADLRPQTQCLPQPCQPGCACPPGQVLQDGACVPPEECRCTLDSTMPGVLNLSREEQEQEHAPGSRLQHRCNTCICIRGTFNCSQEECNVDCLWSPWSPWSPCSVTCGMGE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"table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q30D05-1", "uniprot_ac": "Q30D05", "uniprot_id": "Q30D05_CHICK", "mass": { "chemical_mass": 43558.0, "monoisotopic_mass": 43558.0 }, "refseq": { "ac": "NP_001032913", "name": "neuropeptide Y7 receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" }, "gene_names": [ { "name": "NPY7R", "type": "recommended", "evidence": [ { "id": "Q30D05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ] }, { "name": "NPY7R", "type": "synonym", "evidence": [ { "id": "NP_001032913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] }, { "name": "NPY7", "type": "synonym", "evidence": [ { "id": "NP_001032913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] }, { "name": "Y7", "type": "synonym", "evidence": [ { "id": "NP_001032913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] }, { "name": "cY7", "type": "synonym", "evidence": [ { "id": "NP_001032913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] } ], "protein_names": [ { "name": "Neuropeptide Y receptor type 2", "type": "recommended", "evidence": [ { "id": "Q30D05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q30D05/entry#names_and_taxonomy" } ] }, { "name": "NPY-Y2 receptor", "type": "synonym", "evidence": [ { "id": "Q30D05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q30D05/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide Y7 receptor", "type": "synonym", "evidence": [ { "id": "NP_001032913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01013300.1, HAEL01002723.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On or before Dec 10, 2021 this sequence version replaced XP_015149277.1, XP_414599.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001032913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ] }, { "annotation": "Phylogenetic and chromosomal analysis of chicken Y7 receptor supports the ancient origin of this Y receptor gene by chromosome duplications in an early (pregnathostome) vertebrate ancestor.", "evidence": [ { "database": "RefSeq", "id": "NP_001032913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" }, { "database": "PubMed", "id": "16640567", "url": "https://glygen.org/publication/PubMed/16640567" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPY7R", "url": "https://www.uniprot.org/uniprotkb/Q30D05", "locus": { "chromosome": "13", "start_pos": 12926509, "end_pos": 12949987, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016842", "url": "https://www.ensembl.org/id/ENSGALG00010016842" } ] } } ], "crossref": [ { "id": "ENSGALG00000021303", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021303", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416280", "url": "https://www.ncbi.nlm.nih.gov/gene/416280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416280", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEKWPSG", "url": "https://omabrowser.org/oma/group/SEKWPSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q30D05", "url": "https://www.orthodb.org/?gene=Q30D05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001032913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q30D05-1", "url": "https://www.uniprot.org/uniprotkb/Q30D05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLEGANSTLTMEKLAVDEKLPQGWHTEDSVTPSLDLSGSHSVMMDSTKIPGVQVVLIAAYSLIILLGFIGNSLVIYIIVKYKTMRTVTNLFIANLALADLMVDTLCLPFTLVYTLLDEWKFGAVLCHLVPYAQALSVHVSTLTLTVIALDRYRCIVFHLDSRISRRLSFTIIAIMWLAAAILAGPLAIFREFRYEEIPSINLKMAVCSEKWPSGNNRDATIYSLSMLLLQYVFPLAVICYAYTRIWFKLKNHVSPTSRNENQCRRRKTTKMLVMVVVVFAVCWLPFHIFQLAIDLDLVLIFHEYKLLYTVFHVGAMCSTFVNPLLYGWMNKNYRNGFLMFFRCQNKPESIHAEGSVRGRSYIFRASTLNGSIKHAAGNGPTEV", "length": 385, "header": "tr|Q30D05-1|Q30D05_CHICK Isoform 1 of Neuropeptide Y receptor type 2 OS=Gallus gallus OX=9031 GN=NPY7R PE=3 SV=1 CANONICAL=Q30D05-1" }, "isoforms": [ { "isoform_ac": "Q30D05-1", "url": "https://www.uniprot.org/uniprotkb/Q30D05/entry", "sequence": { "sequence": "MGLLEGANSTLTMEKLAVDEKLPQGWHTEDSVTPSLDLSGSHSVMMDSTKIPGVQVVLIAAYSLIILLGFIGNSLVIYIIVKYKTMRTVTNLFIANLALADLMVDTLCLPFTLVYTLLDEWKFGAVLCHLVPYAQALSVHVSTLTLTVIALDRYRCIVFHLDSRISRRLSFTIIAIMWLAAAILAGPLAIFREFRYEEIPSINLKMAVCSEKWPSGNNRDATIYSLSMLLLQYVFPLAVICYAYTRIWFKLKNHVSPTSRNENQCRRRKTTKMLVMVVVVFAVCWLPFHIFQLAIDLDLVLIFHEYKLLYTVFHVGAMCSTFVNPLLYGWMNKNYRNGFLMFFRCQNKPESIHAEGSVRGRSYIFRASTLNGSIKHAAGNGPTEV", "length": 385, "header": "tr|Q30D05-1|Q30D05_CHICK Isoform 1 of Neuropeptide Y receptor type 2 OS=Gallus gallus OX=9031 GN=NPY7R PE=3 SV=1 CANONICAL=Q30D05-1" }, "locus": { "chromosome": "13", "start_pos": 12930204, "end_pos": 12929541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040625.1", "url": "https://www.ensembl.org/id/ENSGALT00010040625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023592.1", "url": "https://www.ensembl.org/id/ENSGALP00010023592.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Neuropeptide Y-family receptors Y6 and Y7 in chicken. Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region.", "journal": "The FEBS journal", "date": "2006-05", "authors": "Brom\u00e9e Torun, Sj\u00f6din Paula, Fredriksson Robert, Boswell Tim, Larsson Tomas A, Salaneck Erik, Zoorob Rima, Mohell Nina, Larhammar Dan", "evidence": [ { "database": "RefSeq", "id": "NP_001032913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032913" } ], "reference": [ { "type": "PubMed", "id": "16640567", "url": "https://glygen.org/publication/PubMed/16640567" } ] } ], "pathway": [ { "id": "gga:416280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416280", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "Q30D05", "url": "https://www.uniprot.org/uniprotkb/Q30D05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q30D05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q30D05" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 328, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q32TG3-1", "uniprot_ac": "Q32TG3", "uniprot_id": "EFHC2_CHICK", "mass": { "chemical_mass": 86661.0, "monoisotopic_mass": 86661.0 }, "refseq": {}, "gene_names": [ { "name": "EFHC2", "type": "recommended", "evidence": [ { "id": "Q32TG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" } ] } ], "protein_names": [ { "name": "EF-hand domain-containing family member C2", "type": "recommended", "evidence": [ { "id": "Q32TG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32TG3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3#function" }, { "database": "UniProtKB", "id": "A0A3Q1N1R0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1R0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFHC2", "url": "https://www.uniprot.org/uniprotkb/Q32TG3", "locus": { "chromosome": "1", "start_pos": 111193344, "end_pos": 111131909, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011468", "url": "https://www.ensembl.org/id/ENSGALG00010011468" } ] } } ], "crossref": [ { "id": "Q32TG3", "url": "https://alphafold.ebi.ac.uk/entry/Q32TG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q32TG3", "url": "https://www.orthodb.org/?gene=Q32TG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32TG3-1", "url": "https://www.uniprot.org/uniprotkb/Q32TG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPLLPGFSLGRNVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLIPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSMNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLMMPLYSVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 746, "header": "sp|Q32TG3-1|EFHC2_CHICK Isoform 1 of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=2 SV=1 CANONICAL=Q32TG3-1" }, "isoforms": [ { "isoform_ac": "Q32TG3-1", "url": 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CANONICAL=Q32TG3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A new EF-hand containing gene EFHC2 on Xp11.4: tentative evidence for association with juvenile myoclonic epilepsy.", "journal": "Epilepsy Res.", "date": "2005", "authors": "Gu W, Sander T, Heils A, Lenzen KP, Steinlein OK", "evidence": [ { "database": "UniProtKB", "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" } ], "reference": [ { "type": "PubMed", "id": "16112844", "url": "https://glygen.org/publication/PubMed/16112844" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "Q32TG3", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32TG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 746, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32TG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32TG3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q32TG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32TG3" }, { "id": "PRU00665", "database": "PROSITE", "url": 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"end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000236.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001269361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269361" } ] }, { "annotation": "CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) look equally like orthologues of human CXCL8 and are ligands for chicken CXCR1", "evidence": [ { "database": "RefSeq", "id": "NP_001269361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269361" }, { "database": "PubMed", "id": "18417470", "url": "https://glygen.org/publication/PubMed/18417470" } ] }, { "annotation": "Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. 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Involved in the control of actin-cytoskeleton organization (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361#function" }, { "database": "UniProtKB", "id": "Q8TEA7", "url": "https://www.uniprot.org/uniprotkb/Q8TEA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBCK", "url": "https://www.uniprot.org/uniprotkb/Q5F361", "locus": { "chromosome": "4", "start_pos": 38121117, "end_pos": 38005796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006077", "url": "https://www.ensembl.org/id/ENSGALG00010006077" } ] } } ], "crossref": [ { "id": 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"https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422534", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F361", "url": "https://www.orthodb.org/?gene=Q5F361", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24345:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24345:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F361", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F361", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F361-1", "url": "https://www.uniprot.org/uniprotkb/Q5F361-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPLRDTEMGASTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDITRGKHERLVVAAEHCENSLEDLLREGKLVSSSRILCIAYEVLQGLQYMNKHGMVHRALSPRNILLDRKGHVKLAKFGLYHMTAQGVDVDFPIGYPSYLAPEVIAQGMVKPSDHTQCEKPLPSGPKSDLWSLGIILFELCVGRKLFQTLEIAERLKFVITLGYVDDIVTVLAEEHGCLDIIKDLSENVITLLKKCLTFQPSKRPTPEELMHDHLFSEVSLTYPPFHKPAGLFSSSPRCADLTLPEDISQLCKDEDNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPVCTLPNFVLEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSTLPHSNSSSELSAAANLPLIIRERDTEYQLNRIVLFDRLLKAYPYKKNQIWKEARVDIPPLLRGITWAALLGVEGAIQAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFRWTPKSATYRQYAQPPRQANESNGTRSSMSCFSVDYQEAPRGDLSRDSIKLDDLKAEVSPRISAEDLIDLCELTGPSHSKTPIKKTKSSKPKLLVVDIRNSEDFNRGHISGSINVPFASAFTAEGDLIQCPATATLQSFKGRVVVIVGNAVKNTAAFAAHLVKSKYPRVCILDGGINKIKPTGLLTVPSPQI", "length": 893, "header": "sp|Q5F361-1|TBCK_CHICK Isoform 1 of TBC domain-containing protein kinase-like protein OS=Gallus gallus OX=9031 GN=TBCK PE=2 SV=2 CANONICAL=Q5F361-1" }, "isoforms": [ { "isoform_ac": "Q5F361-1", "url": "https://www.uniprot.org/uniprotkb/Q5F361/entry#Q5F361-1", "sequence": { "sequence": "MFPLRDTEMGASTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDITRGKHERLVVAAEHCENSLEDLLREGKLVSSSRILCIAYEVLQGLQYMNKHGMVHRALSPRNILLDRKGHVKLAKFGLYHMTAQGVDVDFPIGYPSYLAPEVIAQGMVKPSDHTQCEKPLPSGPKSDLWSLGIILFELCVGRKLFQTLEIAERLKFVITLGYVDDIVTVLAEEHGCLDIIKDLSENVITLLKKCLTFQPSKRPTPEELMHDHLFSEVSLTYPPFHKPAGLFSSSPRCADLTLPEDISQLCKDEDNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPVCTLPNFVLEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSTLPHSNSSSELSAAANLPLIIRERDTEYQLNRIVLFDRLLKAYPYKKNQIWKEARVDIPPLLRGITWAALLGVEGAIQAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFRWTPKSATYRQYAQPPRQANESNGTRSSMSCFSVDYQEAPRGDLSRDSIKLDDLKAEVSPRISAEDLIDLCELTGPSHSKTPIKKTKSSKPKLLVVDIRNSEDFNRGHISGSINVPFASAFTAEGDLIQCPATATLQSFKGRVVVIVGNAVKNTAAFAAHLVKSKYPRVCILDGGINKIKPTGLLTVPSPQI", "length": 893, "header": "sp|Q5F361-1|TBCK_CHICK Isoform 1 of TBC domain-containing protein kinase-like protein OS=Gallus gallus OX=9031 GN=TBCK PE=2 SV=2 CANONICAL=Q5F361-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Mass spectral data for 64 eluted peptides and structural modeling define peptide binding preferences for class I alleles in two chicken MHC-B haplotypes associated with opposite responses to Marek's disease.", "journal": "Immunogenetics", "date": "2008-09", "authors": "Sherman Mark A, Goto Ronald M, Moore Roger E, Hunt Henry D, Lee Terry D, Miller Marcia M", "evidence": [ { "database": "IEDB", "id": "423711", "url": "https://www.iedb.org/epitope/423711" } ], "reference": [ { "type": "PubMed", "id": "18612635", "url": "https://glygen.org/publication/PubMed/18612635" } ] } ], "pathway": [ { "id": "gga:422534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422534", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q5F361", "url": "https://www.uniprot.org/uniprotkb/Q5F361" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F361-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 893, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F361-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F361" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F361" }, { "id": "PRU00159", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000255", "start_pos": 1, "end_pos": 274, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5F361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F361" }, { "id": "PRU00163", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00163" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000255", "start_pos": 466, "end_pos": 651, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q5F361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F361" }, { "id": "PRU00173", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00173" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000255", "start_pos": 790, "end_pos": 889, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 415, "end_pos": 417 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 724, "end_pos": 726 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F368-1", "uniprot_ac": "Q5F368", "uniprot_id": "P33MX_CHICK", "mass": { "chemical_mass": 31527.0, "monoisotopic_mass": 31527.0 }, "refseq": { "ac": "NP_001025781", "name": "putative monooxygenase p33MONOX", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781" }, "gene_names": [ { "name": "P33MONOX", "type": "recommended", "evidence": [ { "id": "Q5F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ] }, { "name": "KIAA1191", "type": "synonym", "evidence": [ { "id": "NP_001025781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781" } ] }, { "name": "P33MONOX", "type": "synonym", "evidence": [ { "id": "NP_001025781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781" } ] }, { "name": "RCJMB04_31b20", "type": "synonym", "evidence": [ { "id": "Q5F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ] } ], "protein_names": [ { "name": "Putative monooxygenase p33MONOX", "type": "recommended", "evidence": [ { "id": "Q5F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F368/entry#names_and_taxonomy" } ] }, { "name": "1.-.-.-", "type": "synonym", "evidence": [ { "id": "Q5F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F368/entry#names_and_taxonomy" } ] }, { "name": "putative monooxygenase p33MONOX", "type": "synonym", "evidence": [ { "id": "NP_001025781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851782.1, SRR13267655.89359.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ851782.1. On Aug 8, 2005 this sequence version replaced XP_414553.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781" } ] }, { "annotation": "Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "P33MONOX", "url": "https://www.uniprot.org/uniprotkb/Q5F368", "locus": {} } ], "crossref": [ { "id": "Q5F368", "url": "https://alphafold.ebi.ac.uk/entry/Q5F368", "database": "AlphaFoldDB", "categories": [] }, { "id": "416230", "url": "https://www.ncbi.nlm.nih.gov/gene/416230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416230", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F368", "url": "https://www.orthodb.org/?gene=Q5F368", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F368", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F368", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025781", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F368-1", "url": "https://www.uniprot.org/uniprotkb/Q5F368-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGETTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 287, "header": "sp|Q5F368-1|P33MX_CHICK Isoform 1 of Putative monooxygenase p33MONOX OS=Gallus gallus OX=9031 GN=P33MONOX PE=2 SV=1 CANONICAL=Q5F368-1" }, "isoforms": [ { "isoform_ac": "Q5F368-1", "url": "https://www.uniprot.org/uniprotkb/Q5F368/entry#Q5F368-1", "sequence": { "sequence": "MSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGETTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 287, "header": "sp|Q5F368-1|P33MX_CHICK Isoform 1 of Putative monooxygenase p33MONOX OS=Gallus gallus OX=9031 GN=P33MONOX PE=2 SV=1 CANONICAL=Q5F368-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416230", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q5F368", "url": "https://www.uniprot.org/uniprotkb/Q5F368" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F368-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 287, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F368-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F368" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 25, 158 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F371-1", "uniprot_ac": "Q5F371", "uniprot_id": "SBNO1_CHICK", "mass": { "chemical_mass": 137186.0, "monoisotopic_mass": 137186.0 }, "refseq": { "ac": "NP_001026640", "name": "protein strawberry notch homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640" }, "gene_names": [ { "name": "SBNO1", "type": "recommended", "evidence": [ { "id": "Q5F371", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F371" } ] }, { "name": "RCJMB04_30k7", "type": "synonym", "evidence": [ { "id": "Q5F371", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F371" } ] }, { "name": "SBNO1", "type": "synonym", "evidence": [ { "id": "NP_001026640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640" } ] } ], "protein_names": [ { "name": "Protein strawberry notch homolog 1", "type": "recommended", "evidence": [ { "id": "Q5F371", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F371/entry#names_and_taxonomy" } ] }, { "name": "protein strawberry notch homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001026640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640" } ] }, { "name": "sno, strawberry notch homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001026640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851779.1, SRR13267655.9478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Dec 17, 2020 this sequence version replaced NP_001026640.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640" } ] }, { "annotation": "Plays a crucial role in the regulation of neural stem cells (NSCs) proliferation. Enhances the phosphorylation of GSK3B through the PI3K-Akt signaling pathway, thereby upregulating the Wnt/beta-catenin signaling pathway and promoting the proliferation of NSCs.", "evidence": [ { "database": "UniProtKB", "id": "Q5F371", "url": "https://www.uniprot.org/uniprotkb/Q5F371#function" }, { "database": "UniProtKB", "id": "Q689Z5", "url": "https://www.uniprot.org/uniprotkb/Q689Z5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F371", "url": "https://www.uniprot.org/uniprotkb/Q5F371" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SBNO1", "url": "https://www.uniprot.org/uniprotkb/Q5F371", "locus": { "chromosome": "15", "start_pos": 5047465, "end_pos": 5018287, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024812", "url": "https://www.ensembl.org/id/ENSGALG00010024812" } ] } } ], "crossref": [ { "id": "Q5F371", "url": "https://alphafold.ebi.ac.uk/entry/Q5F371", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003392", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003392", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427694", "url": "https://www.ncbi.nlm.nih.gov/gene/427694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427694", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F371", "url": "https://www.orthodb.org/?gene=Q5F371", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12706:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12706:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13871", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13871", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13872", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13872", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F371", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F371", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F371", "url": "https://www.uniprot.org/uniprotkb/Q5F371", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F371-1", "url": "https://www.uniprot.org/uniprotkb/Q5F371-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1239, "header": "sp|Q5F371-1|SBNO1_CHICK Isoform 1 of Protein strawberry notch homolog 1 OS=Gallus gallus OX=9031 GN=SBNO1 PE=2 SV=1 CANONICAL=Q5F371-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function 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The reference sequence was derived from JAENSK010000074.1. 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protein 1 OS=Gallus gallus OX=9031 GN=RELL1 PE=2 SV=1 CANONICAL=Q5F3A4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 25, "start_aa": "Asn", "end_pos": 25, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn25", "evidence": [ { "id": "Q5F3A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3A4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3A4", "url": "https://www.uniprot.org/uniprotkb/Q5F3A4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422795", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QK31-1", "protein_name": "RELT-like protein 1", "gene_name": "rell1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGSSLSTNSTTRGGNGHSGDGHPENIAFILVPFFFLMGLLGVLICHILKRKGYRCTTEAEEEEQLEKERRDEELEKGDLNDTFSEGNADTVGQIVHYIMKNEANSDALKAMVQDSIDSEGGPVTPTTPNTPTSPESPAAPGLPPTAAKHTCNHLHTIGGISGHKNICHRCNQKKWPLLRRSSSKKLDRRSHVGEVTVLSVGRFRVTKCDPKTARERRTLLITEPNGSVSPSPASTHPPEHTPVLQLPKIDVIEEHEN", "length": 258 }, "evidence": [ { "id": "Q5F3A4", "url": "https://omabrowser.org/oma/group/Q5F3A4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S4K9-1", "protein_name": "RELT like 1", "gene_name": "RELL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRGLPGSAVLAAAVFVGGAVSSPLVAPDNGGSRILHSGTKTTPSPTNNTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDVEEEKVEKIEMNDSVNENSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPSTPGSPPVSPGPLSPGGTPGKHICGHHLHTVGGAVERDVCHRCRHKRWHFIRPANKSKEGRPRRQGEVTVLSVGRFRVTKVEHKANQKERRSLMSTGGTESVNGEVPATPVKREQSGPEEQE", "length": 274 }, "evidence": [ { "id": "Q5F3A4", "url": "https://omabrowser.org/oma/group/Q5F3A4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08DP3-1", "protein_name": "RELT-like protein 1", "gene_name": "RELL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPRGLPGSAVLAAAVFVGGAVSSPLVRSDHSGSHPLPSKTETTPSPTNNNGNGHPEYIAYALVPVFFVMGLFGVLICHLLKKKGYRCTTEAEQDVEGEKVEKIELNDSVNENSDTVGQIVQYIMKNEANVDILAAMVEDNNVCDPESPVTPSTPGSPPVSPGPLSPGVTPGKHICGHHLHTVGGPVERDVCHRCRHKRWHFIKPTNKSKEGRPRRQGEVTVLSVGRFRVTKVEPKSNQKERRSLMSVSGTDSVNGEVPVTPVKRQQSDSE", "length": 271 }, "evidence": [ { "id": "Q5F3A4", "url": "https://omabrowser.org/oma/group/Q5F3A4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IUW5-1", "protein_name": "RELT-like protein 1", "gene_name": "RELL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRALPGSAVLAAAVFVGGAVSSPLVAPDNGSSRTLHSRTETTPSPSNDTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDIEEEKVEKIELNDSVNENSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPSTPGSPPVSPGPLSPGGTPGKHVCGHHLHTVGGVVERDVCHRCRHKRWHFIKPTNKSRESRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGAETVNGEVPATPVKRERSGTE", "length": 271 }, "evidence": [ { "id": "Q5F3A4", "url": "https://omabrowser.org/oma/group/Q5F3A4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2J7-1", "protein_name": "RELT-like protein 1", "gene_name": "Rell1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALWGLPGSAVLAASVFVGGAVSSPLVAADNTGSHTLHSRAETTPSSPTNNPGNGHPEYIAYVLVPVFFVMGLLGVLICHLLKKKGYRCTTEAEQEVEEEKVEKIELNDSINENSDTVGQIVQYIMKNEANADILKAMVADNSVGDIESPVTPSTPGSPPVSPGPLSPGATPGKHVCGHHLHTVGGVVERDVCQRCRHKRWHFIKPTNKTKEGRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGIESVNGDVPATPVKRERSDTE", "length": 272 }, "evidence": [ { "id": "Q5F3A4", "url": "https://omabrowser.org/oma/group/Q5F3A4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5F3A4", "url": "https://www.uniprot.org/uniprotkb/Q5F3A4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "Q5F3A4", "url": "https://www.uniprot.org/uniprotkb/Q5F3A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3A4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 288, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3A4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3A4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 25 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3C8-1", "uniprot_ac": "Q5F3C8", "uniprot_id": "PKHO1_CHICK", "mass": { "chemical_mass": 48152.0, "monoisotopic_mass": 48152.0 }, "refseq": { "ac": "NP_001026527", "name": "pleckstrin homology domain-containing family O member 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" }, "gene_names": [ { "name": "PLEKHO1", "type": "recommended", "evidence": [ { "id": "Q5F3C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" } ] }, { "name": "PLEKHO1", "type": "synonym", "evidence": [ { "id": "NP_001026527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" } ] }, { "name": "RCJMB04_21c20", "type": "synonym", "evidence": [ { "id": "Q5F3C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family O member 1", "type": "recommended", "evidence": [ { "id": "Q5F3C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8/entry#names_and_taxonomy" } ] }, { "name": "PH domain-containing family O member 1", "type": "synonym", "evidence": [ { "id": "NP_001026527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" }, { "id": "Q5F3C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8/entry#names_and_taxonomy" } ] }, { "name": "casein kinase-2 interacting protein-1", "type": "synonym", "evidence": [ { "id": "NP_001026527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" } ] }, { "name": "pleckstrin homology domain-containing family O member 1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" } ] }, { "name": "pleckstrin homology domain-containing family O member 1", "type": "synonym", "evidence": [ { "id": "NP_001026527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851722.1, SRR13267655.256176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000344.1. On Nov 10, 2021 this sequence version replaced NP_001026527.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527" } ] }, { "annotation": "Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP).", "evidence": [ { "database": "UniProtKB", "id": "Q5F3C8", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3C8", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHO1", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8", "locus": { "chromosome": "25", "start_pos": 211586, "end_pos": 196075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028502", "url": "https://www.ensembl.org/id/ENSGALG00010028502" } ] } } ], "crossref": [ { "id": "Q5F3C8", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13317", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13317", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426108", "url": "https://www.ncbi.nlm.nih.gov/gene/426108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426108", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3C8", "url": "https://www.orthodb.org/?gene=Q5F3C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15871:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15871:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3C8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3C8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026527", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3C8", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3C8-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKNNSAKRGQQDGNQQSAQPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNVQEAFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSRQPGNMAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDASPEEHSTCEESFRVDLDKSVAQLAAGRRRSDSENVKLSEKGRSGTLPRHEVTSWDKPTQRKDSLDKGTVYTPQVPKKLSHSEKNKCASMEEILSRRDSAHRAVLRRGLEAHCTAAEPEQLSRLQELVALKLEKTQELLTEVKGYGEGKRKVKDCATSTTTSSSSSSSRSDCERILQESERLLGEASSTWSQARRVLQEVRELRDLYRQIELQQVDCNPKQSSQYRKSMM", "length": 423, "header": "sp|Q5F3C8-1|PKHO1_CHICK Isoform 1 of Pleckstrin homology domain-containing family O member 1 OS=Gallus gallus OX=9031 GN=PLEKHO1 PE=2 SV=1 CANONICAL=Q5F3C8-1" }, "isoforms": [ { "isoform_ac": "Q5F3C8-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8/entry#Q5F3C8-1", "sequence": { "sequence": "MEKNNSAKRGQQDGNQQSAQPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNVQEAFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSRQPGNMAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDASPEEHSTCEESFRVDLDKSVAQLAAGRRRSDSENVKLSEKGRSGTLPRHEVTSWDKPTQRKDSLDKGTVYTPQVPKKLSHSEKNKCASMEEILSRRDSAHRAVLRRGLEAHCTAAEPEQLSRLQELVALKLEKTQELLTEVKGYGEGKRKVKDCATSTTTSSSSSSSRSDCERILQESERLLGEASSTWSQARRVLQEVRELRDLYRQIELQQVDCNPKQSSQYRKSMM", "length": 423, "header": "sp|Q5F3C8-1|PKHO1_CHICK Isoform 1 of Pleckstrin homology domain-containing family O member 1 OS=Gallus gallus OX=9031 GN=PLEKHO1 PE=2 SV=1 CANONICAL=Q5F3C8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3C8", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426108", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F3C8", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": 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"site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3C8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 423, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3C8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3C8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F3C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3C8" }, { "id": "PRU00145", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000255", "start_pos": 20, "end_pos": 131, 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NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. 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"MVISKQYHQEIEDFVFNLVHKYEDQQRDEQEKTHFSLKPQPSSVVLEEDYKTASSNSVKKIKEAFSVVGSVLYFTNFCLDKLGQPILNENPQLTEGWEIPKYQQVFSQILSLDGQEIQVKPKRPKSHCFNCGSEEHQIKDCPKPRNAARISEKRKEFMEAYGEASNQNFQQRYHAEEVEERFGKFKPGVISGELQDALGVTAKSLPPFIYRMRQLGYPPGWLKEAEMEHSGLALYDGKDDNETEDEGYLQPKHVTYDVSKLINYPGFNISTPSGIPDEWQIFGSIPMQPSQQKDVFAHYLSNFHAPSSKSSNKRTAPQPSSHHSKRPKDDLEVAVADMDIDSDVEVSQRSQTTNSFQFQPPLPPGPPVISTPPPLPQGTPPLTPRSLTPTQPSTPTHPPLPNTVSSLNPSSDVSQPKIVDSTMDEDTLTLEELEEQQRLIWAALEQAESTNSDSDIPVDTPLTGNSVTSSPSRNEVDVVAEVRSDKMVTLETKFSSISEQVPENEHSLTSPNPDNSSLNLKEIPDNSDSEGLLDNTVPAPNHEVNDGESIVDNKVVTSTESSAKNSNPVPDMSKFAVGIAPFEFENMTESTGTYLRIRSVLKNSPRNQQKKKT", "length": 613, "header": "sp|Q5F3D1-1|ZCHC8_CHICK Isoform 1 of Zinc finger CCHC domain-containing protein 8 OS=Gallus gallus OX=9031 GN=ZCCHC8 PE=2 SV=1 CANONICAL=Q5F3D1-1" }, "isoforms": [ { "isoform_ac": "Q5F3D1-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D1/entry#Q5F3D1-1", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "Q5F3D1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D1" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D1" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": 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"evidence": [ { "id": "NP_001012624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012624" } ] }, { "name": "UTP15, U3 small nucleolar ribonucleoprotein, homolog", "type": "synonym", "evidence": [ { "id": "NP_001012624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012624" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01006062.1, AJ851713.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000089.1. On Feb 28, 2005 this sequence version replaced XP_423821.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012624" } ] }, { "annotation": "Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D7", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7#function" }, { "database": "UniProtKB", "id": "Q8TED0", "url": "https://www.uniprot.org/uniprotkb/Q8TED0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3D7", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UTP15", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7", "locus": { "chromosome": "Z", "start_pos": 25260547, "end_pos": 25270164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011747", "url": "https://www.ensembl.org/id/ENSGALG00010011747" } ] } } ], "crossref": [ { "id": "Q5F3D7", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3D7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013510", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426152", "url": "https://www.ncbi.nlm.nih.gov/gene/426152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426152", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATYQVVH", "url": "https://omabrowser.org/oma/group/ATYQVVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F3D7", "url": "https://www.orthodb.org/?gene=Q5F3D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3D7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3D7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012624", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3D7", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3D7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 520, "header": "sp|Q5F3D7-1|UTP15_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Gallus gallus OX=9031 GN=UTP15 PE=2 SV=1 CANONICAL=Q5F3D7-1" }, "isoforms": [ { "isoform_ac": "Q5F3D7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7/entry#Q5F3D7-1", "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 520, "header": "sp|Q5F3D7-1|UTP15_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Gallus gallus OX=9031 GN=UTP15 PE=2 SV=1 CANONICAL=Q5F3D7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D7", "url": "https://www.uniprot.org/uniprotkb/Q5F3D7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426152", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RRU3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDYAASILSLALSHQDETVVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKIYTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPEEKTESPRQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7MB12-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGYKPVSIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHSVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNTDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYTASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKDSVPRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPTCTIKTPEVTVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLILQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQHNTSDGFLENNKIES", "length": 519 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S2K2-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGYKPVAIQIYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLIAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESVSRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPSCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQQTPDGFLENKRIES", "length": 518 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O82266-1", "protein_name": "Protein SLOW WALKER 1", "gene_name": "SWA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEELRVRLNDHQVSKVFPVKPKSTAKPVSESETPESRYWSSFKNHSTPNLVSSVAALAFSPVHPHSLAVAHSATVSLFSSQSLSSSRRFSFRDVVSSVCFRSDGALFAACDLSGVVQVFDIKERMALRTLRSHSAPARFVKYPVQDKLHLVSGGDDGVVKYWDVAGATVISDLLGHKDYVRCGDCSPVNDSMLVTGSYDHTVKVWDARVHTSNWIAEINHGLPVEDVVYLPSGGLIATAGGNSVKVWDLIGGGKMVCSMESHNKTVTSLRVARMESAESRLVSVALDGYMKVFDYGRAKVTYSMRFPAPLMSLGLSPDGSTRVIGGSNGMVFAGKKKVRDVVGGQKKSLNLWSLISDVDESRRRALRPTYFRYFQRGQSEKPSKDDYLVKEKKGLKLTRHDKLLKKFRHKEALVSVLEEKKPANVVAVMEELVARRKLMKCVSNMEEGELGMLLGFLQRYCTVQRYSGLLMGLTKKVLETRAEDIKGKNEFKGLLRNLKREVNQEIRIQQSLLEIQGVIAPLMRIAGRS", "length": 530 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q04305-1", "protein_name": "U3 small nucleolar RNA-associated protein 15", "gene_name": "UTP15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSPTQIVSCGGNNFKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKEKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPGMAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLELYGNTLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS", "length": 513 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54QV4-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "utp15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMNDYTFLHNLPDVPIPYINPVVTGDSWKLKELQNKKYSSMITRVESNPINSKEVCVTFGNCVRIITSNSKKVEEREITSFRDTPYGASYRDDGKLIVVGGEDPIIKLIDVSSKNTLRKFQGHTGGIQCTRFIEKGSLISGSNDNTVRTWAIETGEQLQMVGKHKDKVHCMTRHPTNGDNIWMTGGYDHCVKLWDIRGNKTQSSTITLDHGAPVEDLIMLGASGTMAISVGGNYFKVWDLLNGSTGKQVYQGTHSMKSLTSIHLSNSKDRFITSGLDHTVRVFSTQSYSLINSYEFSEPLLSLTLINDRKIIAGSAKGTLFYARKTNPITISKAKLSNSDLKNNNIDPVIQLKLKKSQQHNQTLVIDDTLGIYKSSHLDRLLRKFEHKTAFDTAVLLNKNIDFIFKVVCELSRRDALDIVLKNREVSELDSILQMVNKLVNTIKYQQCGILLLEKIVEFYHPSIFQENKSIISTMNSIKINLIKEQKKQSQLLELSGALDLLYSNSTNSNIPKTIQKRKFEEDEQEQEN", "length": 529 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7ZW33-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "utp15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGGRVSLRQFKGHSKAVHATSFLSDGFRVLSGSDDLTCRVWDVASAVELSSITEHTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGNSVMTMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSSNKLLTASLDRHVKVYNSSYKVVHNFDCASSILSLAVAPDDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRGPSYRFFVKGKNFVPRQDDFLVSKPVRQHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQVIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA", "length": 517 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C7V3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKIFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHQDETIVVGMTNGILSVKHRKSEAKKTSLPRRRRPAYRTFIKGKNYLKQRDDIMVSRPAKKHLEGYDKDLKSFRVSQALDRVLEPKCVIRTPEVTVSIIKELTRRGVLANALAGRDEKEVTRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQELVEKEIDYQRELLETLGMMDMLFATMTRNDSDPVPEHVPAELPEEKTESPTQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TED0-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGYKPVAIQTYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILINRPAKKHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMRRKEGTSVLEHTSDGFPENKKIES", "length": 518 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4Z9-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Dmel\\CG3071", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPNAVVSMAVADGDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRADRARKYFVSTKRTNNTQEVDHTIKDHVKGPGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "length": 535 }, "evidence": [ { "id": "Q5F3D7", "url": "https://omabrowser.org/oma/group/Q5F3D7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5F3D7", "url": 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"Protein" ] }, { "id": "Q5F3G0-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3G0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGAPAAGARRGGSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLTLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDSTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 495, "header": "sp|Q5F3G0-1|RHG19_CHICK Isoform 1 of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=2 SV=1 CANONICAL=Q5F3G0-1" }, "isoforms": [ { "isoform_ac": "Q5F3G0-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3G0/entry#Q5F3G0-1", "sequence": { "sequence": 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Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G0", "url": "https://www.uniprot.org/uniprotkb/Q5F3G0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423846", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G0", "url": "https://www.uniprot.org/uniprotkb/Q5F3G0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": 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"id": "IPR043449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q5F3G6", "url": "https://www.orthodb.org/?gene=Q5F3G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15856:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15856:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16660", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16660", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q5F3G6", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3G6-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPALRKEGLKDDEEFVDFKPGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKSMPEDAKGQAREREQIAPELRLVTEVEPKEDWIALVKAAAAAAAKNKAGTKPRTSANSNKDKEERKWLKVPSKKEETSTSTIMQEVQKKEEEPTSSDTFVGFPIVDVPKMAFVQAESTLSHKRKSNLGNSFQAKRARLNKITGLLASKAVVADGAEKKEGNKETAPVLEQEISPKPQIQKKNEADISSSANIQKPALLSSTLSSGKARSKKCKQESGDSSGCIKPPKSPLCPELIQVEDLTLVSQLPSSVINKTSPSQPLNSPRSYKHSQRRRRSQRLATCSLPDDSVEKVSSPSSVTDGKVFSISAQNQQSKLEVPDVAHMSLEKRGPCLPLDLSRSSEVTAPLSTESTFRNEYPSKDKEDIQMITYLSSKAVTDGRVATTASAPSSHVHALHLELPLTNSLKLPKGSSKKKRSSTSVSSEGTEIQYSVPVKEKCFESLKEKILKNVIEKDKHSEVGAVRVERKGKVEEKSSTTYDFLSGKKKEKEKEKKEKKEKDHKSKQKKKKKKKKKSKQHDYSDYEDSSVEFLDRCSSPLTRSSGSSLTLRSMFSEKNTSYQYPRAILSVDLSGENLSDMEFLDDSSTESLLLSGDEYNQDFDSTILKSLRMKTMLSMKLLDAFVNWMKKMAL", "length": 762, "header": "sp|Q5F3G6-1|P20L1_CHICK Isoform 1 of PHD finger protein 20-like protein 1 OS=Gallus gallus OX=9031 GN=PHF20L1 PE=2 SV=1 CANONICAL=Q5F3G6-1" }, "isoforms": [ { "isoform_ac": "Q5F3G6-1", "url": 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CANONICAL=Q5F3G6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G6", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G6", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6" } ], "pmid": "" }, { "name": "NSL complex", "id": "GO:0044545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044545", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G6", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5F3G6", "url": "https://www.uniprot.org/uniprotkb/Q5F3G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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during embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0#function" }, { "database": "UniProtKB", "id": "Q5XJA3", "url": "https://www.uniprot.org/uniprotkb/Q5XJA3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRRC1", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0", "locus": { "chromosome": "Z", "start_pos": 57292122, "end_pos": 57265430, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012640", "url": "https://www.ensembl.org/id/ENSGALG00010012640" } ] } } ], "crossref": [ { "id": "Q5F3I0", "url": 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"MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPIMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTSGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV", "length": 442, "header": "sp|Q5F3I0-1|PRRC1_CHICK Isoform 1 of Protein PRRC1 OS=Gallus gallus OX=9031 GN=PRRC1 PE=2 SV=2 CANONICAL=Q5F3I0-1" }, "isoforms": [ { "isoform_ac": "Q5F3I0-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0/entry#Q5F3I0-1", "sequence": { "sequence": "MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPIMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTSGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV", "length": 442, "header": "sp|Q5F3I0-1|PRRC1_CHICK Isoform 1 of Protein PRRC1 OS=Gallus gallus OX=9031 GN=PRRC1 PE=2 SV=2 CANONICAL=Q5F3I0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:427127", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427127", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I0", "url": "https://www.uniprot.org/uniprotkb/Q5F3I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3I0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 442, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3I0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3I0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 40, 122 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3I6-1", "uniprot_ac": "Q5F3I6", "uniprot_id": "S38AC_CHICK", "mass": { "chemical_mass": 56119.0, "monoisotopic_mass": 56119.0 }, "refseq": { "ac": "NP_001026278", "name": "putative sodium-coupled neutral amino acid transporter 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" }, "gene_names": [ { "name": "SLC38A12", "type": "recommended", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ] }, { "name": "RCJMB04_15p16", "type": "synonym", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ] }, { "name": "SLC38A12", "type": "synonym", "evidence": [ { "id": "NP_001026278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" } ] }, { "name": "TMEM104", "type": "synonym", "evidence": [ { "id": "NP_001026278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" }, { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ] } ], "protein_names": [ { "name": "Putative sodium-coupled neutral amino acid transporter 12", "type": "recommended", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 38 member 12", "type": "synonym", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 104", "type": "synonym", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6/entry#names_and_taxonomy" } ] }, { "name": "putative sodium-coupled neutral amino acid transporter 12", "type": "synonym", "evidence": [ { "id": "NP_001026278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" } ] }, { "name": "solute carrier family 38 member 12", "type": "synonym", "evidence": [ { "id": "NP_001026278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851664.1, SRR13267654.13233.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000317.1. On Sep 23, 2021 this sequence version replaced NP_001026278.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026278" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3I6", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A12", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6", "locus": {} } ], "crossref": [ { "id": "Q5F3I6", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3I6", "database": "AlphaFoldDB", "categories": [] }, { "id": "422110", "url": "https://www.ncbi.nlm.nih.gov/gene/422110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422110", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422110", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3I6", "url": "https://www.orthodb.org/?gene=Q5F3I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16189:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16189:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3I6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3I6", "database": "PRO", "categories": [ "Protein" ] }, { "id": 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neutral amino acid transporter 12 OS=Gallus gallus OX=9031 GN=SLC38A12 PE=2 SV=1 CANONICAL=Q5F3I6-1" }, "isoforms": [ { "isoform_ac": "Q5F3I6-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6/entry#Q5F3I6-1", "sequence": { "sequence": "MAGGITDTGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLMFLGFMSYMTTTFVVEAMAAANAQLRWKRMEKRKEDDEDEDSSSGVSDSDVLLRDSYERAETRPILSVQRRGSPNIFEITERVEMGQMASMFFNKVGVNLFYFCIIIYLYGDLAIYAAAVPVSLMQVTCAIGNHSCNVGDGTKYNDTDKCWGPIRRIDAYRLYLAAFTLLLGPFTFFNVQKTKYLQIMTSLMRWIAFILMIILALIRISRGQAEGHPSMAQLSGIRNLFGVCVYSFMCQHSLPSLITPISKKRHVNKLVLLDYILILAFYSLLSFTAIYCFRNDTLMDMYTLNFTNCEIINVAFIRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPWLVDRIVFPAITLVPPVLVVFCTHDLESLVGITGAYAGNGIQYLIPAFLAYCSRKDTQLVFGSGTVNKHLSPFRHTFWIVFVLIWGFSCFVFVTANIVLSESKL", "length": 497, "header": "sp|Q5F3I6-1|S38AC_CHICK Isoform 1 of Putative sodium-coupled neutral amino acid transporter 12 OS=Gallus gallus OX=9031 GN=SLC38A12 PE=2 SV=1 CANONICAL=Q5F3I6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 194, "start_aa": "Asn", "end_pos": 194, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn194", "evidence": [ { "id": "Q5F3I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I6", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422110", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422110", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I6", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I6", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q5F3I6", "url": "https://www.uniprot.org/uniprotkb/Q5F3I6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3I6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 497, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3I6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3I6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 194 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3L3-1", "uniprot_ac": "Q5F3L3", "uniprot_id": "F234B_CHICK", "mass": { "chemical_mass": 67647.0, "monoisotopic_mass": 67647.0 }, "refseq": { "ac": "NP_001012830", "name": "protein FAM234B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830" }, "gene_names": [ { "name": "FAM234B", "type": "recommended", "evidence": [ { "id": "Q5F3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ] }, { "name": "FAM234B", "type": "synonym", "evidence": [ { "id": "NP_001012830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830" } ] }, { "name": "KIAA1467", "type": "synonym", "evidence": [ { "id": "NP_001012830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830" }, { "id": "Q5F3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ] }, { "name": "RCJMB04_14d19", "type": "synonym", "evidence": [ { "id": "Q5F3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ] } ], "protein_names": [ { "name": "Protein FAM234B", "type": "recommended", "evidence": [ { "id": "Q5F3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM234B", "type": "synonym", "evidence": [ { "id": "NP_001012830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851637.1, SRR13267656.1226.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Mar 14, 2005 this sequence version replaced XP_416202.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3L3", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM234B", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3", "locus": { "chromosome": "1", "start_pos": 48328268, "end_pos": 48306429, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011027", "url": "https://www.ensembl.org/id/ENSGALG00010011027" } ] } } ], "crossref": [ { "id": "Q5F3L3", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417963", "url": "https://www.ncbi.nlm.nih.gov/gene/417963", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417963", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417963", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFQHSAN", "url": "https://omabrowser.org/oma/group/FFQHSAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F3L3", "url": "https://www.orthodb.org/?gene=Q5F3L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21419:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21419:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3L3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3L3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3L3", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3L3-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNIQKNGGVKNGKSPPEEMQDPDSDVEVGMTKQHTSERAPEGYPAEAAGSLEQKAAPSLMPYLRTAVFLLTVVISMILVLVCAFLIPCPPRDLHNTWNHNLGQGAGGVLSPLELCDVNGDGLPDILIVFTALMNASVMGVSTPSVTVVALSGMNGSTLWSIQLPEETRSVQCKGLSLGSPAEPICLVTGTAKFLSLLSASTGKTIWTLNSIHLSDGILAAPAATLPDVDGDGIRDIVVLALKETQPDVFFVLVSGKTGAALGGPVKYNVIGEGKVIGPQVHITSRGAIYILFGFGNVQAIALRDIFTQARNRDSFPMMLHQEEPEWEKRRSVNLSELIDIYSGGVDFLQTIKAPDTNCSNLLITTKEGLILLQGQDLEPRWTLEIQNISSQPVLGYFSADQTLDFMLQAQTGNGKKKVVVVDGKSGLPVWKQELPWQKQQLDALSVMTLDKKSVFLFWADEAQPVLHSLHPGPRSERPGLHHLYLLHPVFPTVLLDLTNATDKVIASAVGINDLQKDAFHITVTTTATSEKQPGFLSVSKLGLKWAMMTQGRMVWLKDTTTPKISRGEVRRFLARLKFVDFPHKL", "length": 623, "header": "sp|Q5F3L3-1|F234B_CHICK Isoform 1 of Protein FAM234B OS=Gallus gallus OX=9031 GN=FAM234B PE=2 SV=1 CANONICAL=Q5F3L3-1" }, "isoforms": [ { "isoform_ac": "Q5F3L3-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3/entry#Q5F3L3-1", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNIQKNGGVKNGKSPPEEMQDPDSDVEVGMTKQHTSERAPEGYPAEAAGSLEQKAAPSLMPYLRTAVFLLTVVISMILVLVCAFLIPCPPRDLHNTWNHNLGQGAGGVLSPLELCDVNGDGLPDILIVFTALMNASVMGVSTPSVTVVALSGMNGSTLWSIQLPEETRSVQCKGLSLGSPAEPICLVTGTAKFLSLLSASTGKTIWTLNSIHLSDGILAAPAATLPDVDGDGIRDIVVLALKETQPDVFFVLVSGKTGAALGGPVKYNVIGEGKVIGPQVHITSRGAIYILFGFGNVQAIALRDIFTQARNRDSFPMMLHQEEPEWEKRRSVNLSELIDIYSGGVDFLQTIKAPDTNCSNLLITTKEGLILLQGQDLEPRWTLEIQNISSQPVLGYFSADQTLDFMLQAQTGNGKKKVVVVDGKSGLPVWKQELPWQKQQLDALSVMTLDKKSVFLFWADEAQPVLHSLHPGPRSERPGLHHLYLLHPVFPTVLLDLTNATDKVIASAVGINDLQKDAFHITVTTTATSEKQPGFLSVSKLGLKWAMMTQGRMVWLKDTTTPKISRGEVRRFLARLKFVDFPHKL", "length": 623, "header": "sp|Q5F3L3-1|F234B_CHICK Isoform 1 of Protein FAM234B OS=Gallus gallus OX=9031 GN=FAM234B PE=2 SV=1 CANONICAL=Q5F3L3-1" }, "locus": { "chromosome": "1", "start_pos": 48326190, "end_pos": 48306437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026414.1", "url": "https://www.ensembl.org/id/ENSGALT00010026414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015028.1", "url": "https://www.ensembl.org/id/ENSGALP00010015028.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L3", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417963", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZWF4-1", "protein_name": "Family with sequence similarity 234 member B", "gene_name": "FAM234B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGQSPLGEAPEPDSDAEPAGSAKPHLSEVTTEGYPLEPLGGLEQKAASSMASYVRTSVFLLMLVVSTVLVLVCAFLIPCPPRDLHSTWSRRLGPQGGGDLNPLELADVNGDGLRDVLLSFVTLRNGSTAGVSRPPALLVCLSGMNGSTLWSSPLPEEARDVTCLDLMPGSGAGTVCLVTGTHKMLSAFNGTSGKAIWTLNPNYLSNGTLAAPGVMLPDLDEDGVRDLVVLAIGEVQPDLCFLLVSGRTGSPVGRPVKYSIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSYGVELLQMVKAADSNCSNLLITTRQGLVLLRGQNLTPSWTLSLQGLRSQPTPGYFTDDETLDFLLQIPSGTGMKKVMVVDGDSGLVTWSYSVPCRMRETPTTSAATVDQKSVFLFWAEGLSAPSPSSDVTLGTEAPDLHHLYLLHPAFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQVVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 623 }, "evidence": [ { "id": "Q5F3L3", "url": "https://omabrowser.org/oma/group/Q5F3L3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TTA4-1", "protein_name": "Family with sequence similarity 234 member B", "gene_name": "FAM234B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSPLGEAPEPDSDAEVAGAGKPRLSEVTPEGYPLEPLGALEQKAASSVVSCVRTSVFLLMLVVSMVLVLVCAFLIPCPPRDLHSTWSRHLGPQGGGDLSPLDLADVNGDGLRDVLLSFVPAGNGSAAGVSRPPAVLVCLSGMNGSTLWSSPLPEEARDITCLDLTPGNMAKTVCLVTGTHKMLSAFNGTSGKAMWTLNPNYLSNGTLAAPAVVLPDVDEDGVRDLAVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITTSGAAYILFGFGNIQAVALRDIFVQAQNRDSLPPSLQIEEPEWEKRRSVNLSELIDVYSDGVELLQMVKAPDSNSSNLLITTTQGLVLLRGQNLTPSWVLGLQGLHSQPTPGYFTDDETIDFLLQIPNGVGMKKVMVVDGDSGLVTWSYSIPCHMKETPATSAATVEQKSVFLFWAEGLSAASPNPDVVLGTEPPSLHHLYLLHPTFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQMVQLEETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 623 }, "evidence": [ { "id": "Q5F3L3", "url": "https://omabrowser.org/oma/group/Q5F3L3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2RU67-1", "protein_name": "Protein FAM234B", "gene_name": "FAM234B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQKNGGVKNGKSPLGEAPEPDSDAEVAEAAKPHLSEVTTEGYPSEPLGGLEQKAASSLVSYVRTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNGDGLRDVLLSFVMSRNGSAVGVSRPAANLVCLSGMNGSTLWSSLLPEEARDITCLELMPGSLAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGNPVGRPVKYNIVGVGNLIGPQVYITTNGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSDGVELLQMVKAPDSNCSNLLITTRQSLVLLRGQNLTPYWALRLQGLRSQPTPGYFTDDQTLDFLLQIQDGVGMKKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSVFLFWAEGLSAASPNSDIILGTEPPSLHHLYLLHPAFPSILLDLANTTGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAALVVSKLSLRWALMEGQMAQLQESTPKIGRGELRRFLSRIKFVEAPYEI", "length": 622 }, "evidence": [ { "id": "Q5F3L3", "url": "https://omabrowser.org/oma/group/Q5F3L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZWJ9-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDPPEPDSDADVAGASKPHLSEVTPEGFPSEPLGGLEQKATSSLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSTWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGGGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKILWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGVGMKKMTVVDGSSGSIVWSYRVPCHVKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPSGLYHLYLLHPAFPSVLLDLSNTTGIVTAAEVGVNDIWKDAFYVTRTTGMSPEGHTTSLVVSKLSLRWGLMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 624 }, "evidence": [ { "id": "Q5F3L3", "url": "https://omabrowser.org/oma/group/Q5F3L3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BYI8-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDLPEPDSDADVAGAAKPHLSEVTPEGFPSEPLGGLEQKATSPLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSAWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGVGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNPNHLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGDGMKKMTVVDGGSGSIVWSYSIPCHMKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPPGLYHLYLLHPAFPSILLDLSNTTGIVTASEVGINDIWKDAFYVTRTTGMSPEGHPTSLVVSKLSLRWALMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 624 }, "evidence": [ { "id": "Q5F3L3", "url": "https://omabrowser.org/oma/group/Q5F3L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L3", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L3", "url": "https://www.uniprot.org/uniprotkb/Q5F3L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3L3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3L3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3L3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5F3L4-1", "uniprot_ac": "Q5F3L4", "uniprot_id": "DEN6A_CHICK", "mass": { "chemical_mass": 67051.0, "monoisotopic_mass": 67051.0 }, "refseq": { "ac": "NP_001012799", "name": "protein DENND6A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" }, "gene_names": [ { "name": "DENND6A", "type": "recommended", "evidence": [ { "id": "Q5F3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4" } ] }, { "name": "DENND6A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "name": "FAM116A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "name": "RCJMB04_14d15", "type": "synonym", "evidence": [ { "id": "Q5F3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4" } ] } ], "protein_names": [ { "name": "Protein DENND6A", "type": "recommended", "evidence": [ { "id": "Q5F3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 6A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" }, { "id": "Q5F3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4/entry#names_and_taxonomy" } ] }, { "name": "DENN/MADD domain containing 6A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "name": "family with sequence similarity 116, member A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "name": "protein DENND6A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "name": "protein FAM116A", "type": "synonym", "evidence": [ { "id": "NP_001012799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851636.1, SRR13267655.77682.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Oct 20, 2021 this sequence version replaced NP_001012799.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799" } ] }, { "annotation": "Guanine nucleotide exchange factor (GEF) for RAB14.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L4", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3L4", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND6A", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4", "locus": { "chromosome": "12", "start_pos": 8915601, "end_pos": 8938839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027083", "url": "https://www.ensembl.org/id/ENSGALG00010027083" } ] } } ], "crossref": [ { "id": "Q5F3L4", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3L4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416006", "url": "https://www.ncbi.nlm.nih.gov/gene/416006", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416006", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416006", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3L4", "url": "https://www.orthodb.org/?gene=Q5F3L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3L4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3L4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3L4", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3L4-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLDKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQNLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 584, "header": "sp|Q5F3L4-1|DEN6A_CHICK Isoform 1 of Protein DENND6A OS=Gallus gallus OX=9031 GN=DENND6A PE=2 SV=1 CANONICAL=Q5F3L4-1" }, "isoforms": [ { "isoform_ac": "Q5F3L4-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4/entry#Q5F3L4-1", "sequence": { "sequence": "MALWERGAGGAAEAGEDATEEPERGLPLLPWDRFSAWLHCVCVVGFDLELGQAVEVIYPPHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRRSSGRKASLCCFLDHLDRDLPVYLKKDPAYYYGYVYFRQVRDKSLKRGYFQKSLVLISKLPYIHLFRTVLKQIAPEYFEKSEAFLEAVCSDVDRWPPPVPGEVLHLPIMGVVMKLRIPTYRDKPGTTPVVQNMHQADAQISMTLPTVHEVDLFRCFCPVFFHIQMLWELVLLGEPLVVMAPSPAESSETVLALVSCISPLKYCSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDMKLPGDVPKQVKVKKLKNLKTLDSKPGVYTSYKPYLDKDEEIVKQLQKGVQQKRPTEAQSAILRRYFLELTESFIIPLERYVASLMPLQKCISPWKSPPQLRHFSQDDFMKTLEKAGPQLTSGLKGDWIGLYRHFLKSPNFDGWFRSRQKEMTQNLEALHLEALCNENLVFWSQKHTEVETVDLVLKLKNKLLQADREHLPVKTDTLKKLQTHIRDIILALPDDLQDILLKTGTA", "length": 584, "header": "sp|Q5F3L4-1|DEN6A_CHICK Isoform 1 of Protein DENND6A OS=Gallus gallus OX=9031 GN=DENND6A PE=2 SV=1 CANONICAL=Q5F3L4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L4", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416006", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416006", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L4", "url": "https://www.uniprot.org/uniprotkb/Q5F3L4" } ], "pmid": "" } ] }, { "name": "Biological 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